FedInvent™ Patents

Patent Details for Tuesday, January 01, 2019 

This page was updated on Monday, March 27, 2023 at 05:42 AM GMT

Department of Health and Human Services (HHS) 

US 10165773 Neff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
U.S. State Government
State of Oregon
APPLICANT(S) Jennifer A. Neff (Rancho Santa Margarita, California);  Joseph McGuire (Corvallis, Oregon);  Pranav Joshi (Bangalore, India)
ASSIGNEE(S) Allvivio Vascular, Inc. (Lake Forest, California);  State of Oregon acting by and through the State Board of Higher Ed. on Behalf of Oregon State Univ. (Corvallis, Oregon)
INVENTOR(S) Jennifer A. Neff (Rancho Santa Margarita, California);  Joseph McGuire (Corvallis, Oregon);  Pranav R. Joshi (Bangalore, India)
ABSTRACT The invention is based on the recognition that known antimicrobial compounds, such as nisin or other lantibiotics, can be made to form a long lasting antimicrobial surface coating by linking the peptide with a block polymer, such as PLURONIC® F108 or an end group activated polymer (EGAP) in a manner to form a flexible tether and/or entrap the peptide. The entrapped peptide provides antimicrobial action by early release from entrapment while the tethered peptide provides longer lasting antimicrobial protection. Antimicrobial gels and foams may be prepared using the antimicrobial peptide containing block copolymers.
FILED Wednesday, August 20, 2014
APPL NO 14/464589
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 25/10 (20130101) Original (OR) Class
A01N 25/10 (20130101)
A01N 25/10 (20130101)
A01N 25/34 (20130101)
A01N 25/34 (20130101)
A01N 25/34 (20130101)
A01N 37/46 (20130101)
A01N 43/90 (20130101)
A01N 43/90 (20130101)
A01N 63/02 (20130101)
A01N 63/02 (20130101)
A01N 2300/00 (20130101)

Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 3/3463 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 47/48215 (20130101)
A61K 47/48992 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/232 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 65/3348 (20130101)
C08G 2650/58 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 9/08 (20130101)
C08K 2201/013 (20130101)

Compositions of Macromolecular Compounds
C08L 71/02 (20130101)
C08L 71/02 (20130101)
C08L 2205/05 (20130101)
C08L 2666/02 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/1352 (20150115)
Y10T 428/1376 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10165781 Dimopoulos et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) George Dimopoulos (Baltimore, Maryland);  Sarah M. Short (Baltimore, Maryland);  Jose L. Ramirez (Rockville, Maryland)
ABSTRACT The present invention relates to the fields of malaria and dengue virus. More specifically, the present invention provides compositions and methods useful for the treatment and prevention of malaria and dengue virus. In particular embodiments, a composition comprises mosquito nectar feed and Chromobacterium sp_Panamam (Csp_P).
FILED Friday, August 28, 2015
APPL NO 15/507332
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 63/02 (20130101) Original (OR) Class

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7004 (20130101)
A61K 35/74 (20130101)
A61K 2300/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 1/01 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/385 (20180101)
Y02A 50/411 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10165788 Mills et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) David Mills (Davis, California);  Daniel Garrido (Santiago, Chile);  Santiago Ruiz-Moyano (Badajoz, Spain);  Carlito Lebrilla (Davis, California);  J. Bruce German (Davis, California)
ABSTRACT Pre-biotic compositions containing oligosaccharides and probiotic compositions useful for treatment of a subject are provided herein. Also provided are methods for administering probiotic or pre-biotic compositions.
FILED Monday, June 16, 2014
APPL NO 14/305868
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 1/3014 (20130101) Original (OR) Class
A23L 33/135 (20160801)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)
A23V 2002/00 (20130101)
A23V 2200/32 (20130101)
A23V 2200/3202 (20130101)
A23V 2200/3204 (20130101)
A23V 2250/28 (20130101)

Indexing Scheme Relating to Lactic or Propionic Acid Bacteria Used in Foodstuffs or Food Preparation
A23Y 2220/17 (20130101)
A23Y 2220/63 (20130101)
A23Y 2220/73 (20130101)
A23Y 2300/19 (20130101)
A23Y 2300/29 (20130101)
A23Y 2300/31 (20130101)
A23Y 2300/39 (20130101)
A23Y 2300/55 (20130101)
A23Y 2300/59 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 35/745 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166204 Spiegel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Enzo Therapeutics, Inc. (Farmingdale, New York);  Virginia Commonwealth University (Richmond, Virginia)
ASSIGNEE(S) Enzo Therapeutics, Inc. (Farmingdale, New York)
INVENTOR(S) Sarah Spiegel (Richmond, Virginia);  Robert Elliot Zipkin (Wynnewood, Pennsylvania);  Jeffrey Kroll Adams (Fort Washington, Pennsylvania)
ABSTRACT Provided are inhibitors of sphingosine kinase Type I that are useful in a number of applications, indications and diseases, as well as for monitoring pharmacokinetics and patient management. These compounds are applicable to treating tumors of the central nervous system, such as glioblastoma multiforme (GBM).
FILED Monday, April 16, 2018
APPL NO 15/954131
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/40 (20130101)
A61K 31/135 (20130101) Original (OR) Class

Acyclic or Carbocyclic Compounds
C07C 215/28 (20130101)
C07C 217/64 (20130101)
C07C 233/18 (20130101)
C07C 323/32 (20130101)

Heterocyclic Compounds
C07D 263/06 (20130101)
C07D 295/092 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166244 Simard
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Maryland, Baltimore (Baltimore, Maryland);  The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University of Maryland, Baltimore (Baltimore, Maryland);  The United States of America as Represented by the Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S) J. Marc Simard (Baltimore, Maryland)
ABSTRACT The present invention concerns protection of an organ or tissue outside of the central nervous system following an ischemic episode. In particular aspects, the invention concerns organ preservation for transplantation, angina pectoris, kidney reperfusion injury, and so forth. In specific embodiments, the organ is subjected to an inhibitor of an NCCa-ATP channel that is regulated by SUR1. Exemplary inhibitors include sulfonylurea compounds, such as glibenclamide, for example.
FILED Monday, December 05, 2016
APPL NO 15/369056
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/57 (20130101) Original (OR) Class
A61K 31/427 (20130101)
A61K 31/565 (20130101)
A61K 38/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6872 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166248 Oates et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) John A. Oates (Nashville, Tennessee);  Olivier Boutaud (Nashville, Tennessee);  Irene Zagol-Ikapitte (Nashville, Tennessee)
ABSTRACT A method of preventing or reducing the occurrence of malondiadehyde and/or levuglandin protein modification in a subject in need thereof, comprising administering to said subject an effective amount of at least one γ-KA scavenger compound, or a pharmaceutically acceptable salt thereof.
FILED Wednesday, December 21, 2016
APPL NO 15/387507
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0226 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/609 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/00 (20180101)
A61P 7/02 (20180101)
A61P 7/06 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166251 Wasik et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Mariusz A. Wasik (Ardmore, Pennsylvania);  Qian Zhang (Philadelphia, Pennsylvania)
ABSTRACT The invention provides methods of inhibiting epigenetic gene silencing in a cell expressing NPM/ALK or decreasing NPM/ALK content in a cell, by contacting a cell with an agent capable of increasing the concentration of Stat5a protein or its functional analog. Further, the invention provides a method of treating malignancies expressing oncogenic kinase by administering to a patient affected with a malignancy an agent capable of increasing the concentration of Stat5a protein or its epigenetically silenced functional tumor suppressor analog in a malignant cell. Finally, it provides a method to diagnose malignancy and monitor patient's response to therapy by analysis of the degree of DNA methylation of the gene encoding for Stat5a or its analog, their mRNA, or protein.
FILED Thursday, October 13, 2016
APPL NO 15/292434
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/706 (20130101) Original (OR) Class
A61K 31/5355 (20130101)
A61K 38/1709 (20130101)
A61K 39/3955 (20130101)

Peptides
C07K 16/18 (20130101)
C07K 16/3061 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1135 (20130101)
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/485 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57484 (20130101)
G01N 2333/91011 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166254 Hematti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Peiman Hematti (Middleton, Wisconsin);  Myriam N. Bouchlaka (Madison, Wisconsin);  Christian M. Capitini (Madison, Wisconsin)
ABSTRACT The present invention relates to methods for treating and preventing graft-versus-host disease (GVHD) and radiation-induced tissue damage or organ failure. More particularly, methods of the present invention comprise administering a therapeutically effective amount of mesenchymal stem cell-educated macrophages (MEMs) to a subject to treat or prevent GVHD, bone marrow failure, radiation-induced tissue damage or organ failure, or a condition associated with aberrant inflammation.
FILED Friday, September 18, 2015
APPL NO 14/858896
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/15 (20130101) Original (OR) Class
A61K 35/15 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166255 Moriarity et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota);  INTIMA BIOSCIENCE, INC. (New York, New York);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota);  INTIMA BIOSCIENCE, INC. (New York, New York);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH and HUMAN SERVICES (Washington, District of Columbia)
INVENTOR(S) Branden Moriarity (Shoreview, Minnesota);  Beau Webber (Coon Rapids, Minnesota);  R. Scott McIvor (St. Louis Park, Minnesota);  Modassir Choudhry (New York, New York);  Steven A. Rosenberg (Potomac, Maryland);  Douglas C. Palmer (North Bethesda, Maryland);  Nicholas P. Restifo (Chevy Chase, Maryland)
ABSTRACT Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.
FILED Friday, July 29, 2016
APPL NO 15/224151
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class

Peptides
C07K 14/4718 (20130101)
C07K 14/7051 (20130101)
C07K 14/7158 (20130101)
C07K 14/70503 (20130101)
C07K 14/70521 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 9/22 (20130101)
C12N 9/96 (20130101)
C12N 15/87 (20130101)
C12N 15/113 (20130101)
C12N 15/907 (20130101)
C12N 2310/20 (20170501)
C12N 2510/00 (20130101)
C12N 2800/80 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/463 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166268 Mendelowitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) David Mendelowitz (Vienna, Virginia);  Vivek Jain (McLean, Virginia);  Heather Jameson (Arlington, Virginia);  Jay Shawn Kimbro (Stevensville, Maryland)
ASSIGNEE(S) THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia)
INVENTOR(S) David Mendelowitz (Vienna, Virginia);  Vivek Jain (McLean, Virginia);  Heather Jameson (Arlington, Virginia);  Jay Shawn Kimbro (Stevensville, Maryland)
ABSTRACT The present disclosure provides methods for treating obstructive sleep apnea (OSA) and OSA induced cardiorespiratory diseases. The disclosure provides, inter alia, methods for treating or alleviating: OSA or OSA induced hypertension, cardiac arrhythmias, myocardial ischemia, sudden cardiac death or stroke, by administering oxytocin. The disclosure further provides methods for improving sleep satisfaction in OSA patients by administering oxytocin.
FILED Thursday, July 02, 2015
APPL NO 15/327252
ART UNIT 1676 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0043 (20130101)
A61K 38/11 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166271 Mulugeta et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Million Mulugeta (Culver City, California);  Lixin Wang (Los Angeles, California);  Yvette Taché (Los Angeles, California);  Jean Rivier (La Jolla, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California)
INVENTOR(S) Million Mulugeta (Culver City, California);  Lixin Wang (Los Angeles, California);  Yvette Taché (Los Angeles, California);  Jean Rivier (La Jolla, California)
ABSTRACT This disclosure reveals that cyclic corticotrophin releasing factor (CRF) antagonist peptides (such as astressin B, its functional fragments, and their derivatives) induce hair growth and prevent hair loss in vivo. This important discovery enables, for instance, methods of promoting hair growth, and methods of treating hair loss (such as the hair loss that occurs normally in some individuals or that is the result of a health disorder or therapeutic treatment). Exemplary cyclic CRF antagonist peptides useful in the disclosed methods are provided throughout the disclosure.
FILED Wednesday, June 20, 2007
APPL NO 11/766012
ART UNIT 1676 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/17 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166273 Wittrup et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Karl Dane Wittrup (Chestnut Hill, Massachusetts);  Jennifer R. Cochran (Stanford, California);  Byron Hua Kwan (Boston, Massachusetts)
ABSTRACT The present invention provides a method of treating cancer with a combination of IL-2 and an integrin-binding-Fc fusion protein. The methods of the invention can be applied to a broad range of cancer types.
FILED Wednesday, August 12, 2015
APPL NO 15/501028
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/16 (20130101)
A61K 38/179 (20130101)
A61K 38/179 (20130101)
A61K 38/385 (20130101)
A61K 38/2013 (20130101) Original (OR) Class
A61K 38/2013 (20130101)
A61K 39/39558 (20130101)
A61K 39/39558 (20130101)
A61K 45/06 (20130101)
A61K 47/48215 (20130101)
A61K 2039/505 (20130101)
A61K 2039/507 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 14/55 (20130101)
C07K 16/22 (20130101)
C07K 16/28 (20130101)
C07K 16/30 (20130101)
C07K 16/40 (20130101)
C07K 16/249 (20130101)
C07K 16/2803 (20130101)
C07K 16/2812 (20130101)
C07K 16/2815 (20130101)
C07K 16/2818 (20130101)
C07K 16/3053 (20130101)
C07K 2317/52 (20130101)
C07K 2317/71 (20130101)
C07K 2317/76 (20130101)
C07K 2319/30 (20130101)
C07K 2319/31 (20130101)
C07K 2319/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166277 Rome et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The United States of America represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Leonard H. Rome (Los Angeles, California);  Valerie A. Kickhoefer (Sherman Oaks, California);  Sherven Sharma (Oakland, California);  Steven M. Dubinett (Los Angeles, California);  Isaac Yang (Los Angeles, California);  Linda M. Liau (Los Angeles, California);  Kathleen A. Kelly (Pacific Palisades, California);  Jian Yang (Los Angeles, California);  Upendra K. Kar (Oakland, California);  Cheryl Champion (Greensboro, Georgia);  Janina Jiang (Los Angeles, California)
ABSTRACT The invention relates to compositions of vault complexes for use as adjuvants for stimulating a cellular immune response to an antigen, for example a tumor antigen, and methods of using the vault complexes in the treatment of diseases, such as cancer.
FILED Monday, September 05, 2016
APPL NO 15/256683
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5052 (20130101)
A61K 38/19 (20130101)
A61K 38/45 (20130101)
A61K 38/177 (20130101)
A61K 38/195 (20130101)
A61K 39/0011 (20130101) Original (OR) Class
A61K 47/646 (20170801)
A61K 47/6925 (20170801)
A61K 2039/57 (20130101)
A61K 2039/64 (20130101)
A61K 2039/572 (20130101)
A61K 2039/575 (20130101)
A61K 2039/645 (20130101)
A61K 2039/6031 (20130101)
A61K 2039/6081 (20130101)
A61K 2039/55516 (20130101)

Peptides
C07K 14/00 (20130101)
C07K 14/77 (20130101)
C07K 2319/00 (20130101)
C07K 2319/01 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2710/14043 (20130101)

Enzymes
C12Y 204/0203 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166285 Cohen et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Jeffrey I. Cohen (Silver Spring, Maryland);  Lesley Pesnicak (Stafford, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Jeffrey I. Cohen (Silver Spring, Maryland);  Lesley Pesnicak (Stafford, Virginia)
ABSTRACT The disclosure provides recombinant herpes virus with diminished latency. In embodiments, the recombinant herpes virus comprises a latency gene or transcript linked to an altered or heterologous promoter. The disclosure also provides compositions and methods for inducing immunity in animals using the recombinant herpes viruses.
FILED Friday, November 09, 2007
APPL NO 12/514011
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/25 (20130101) Original (OR) Class
A61K 39/245 (20130101)
A61K 2039/5254 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 2710/16022 (20130101)
C12N 2710/16722 (20130101)
C12N 2710/16734 (20130101)
C12N 2710/16743 (20130101)
C12N 2710/16761 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166291 Davis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Mark E. Davis (Pasadena, California);  Han Han (Belmont, California)
ABSTRACT Described herein are carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a nitroboronic boronic acid and a linkage cleavable under reducing conditions, configured to present the polymer containing the nitroboronic acid to an environment external to the nanoparticle. Targeted versions of the described nanoparticles are also described, as are related compositions, methods and systems.
FILED Wednesday, October 12, 2016
APPL NO 15/291485
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5161 (20130101)
A61K 31/337 (20130101)
A61K 31/337 (20130101)
A61K 31/727 (20130101)
A61K 31/727 (20130101)
A61K 31/4745 (20130101)
A61K 31/4745 (20130101)
A61K 45/06 (20130101) Original (OR) Class
A61K 47/60 (20170801)
A61K 47/6935 (20170801)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166292 Hoelzinger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota);  Flory Mitrani (Scottsdale, Arizona)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Dominique B. Hoelzinger (Phoenix, Arizona);  Sandra J. Gendler (Scottsdale, Arizona);  Peter A. Cohen (Scottsdale, Arizona);  Ana L. Dominguez (Scottsdale, Arizona);  Shannon E. Smith (Spring Valley, California);  Joseph Lustgarten (Scottsdale, Arizona)
ABSTRACT This document provides methods and materials related to using inhibitors of IL-9 signaling in conjunction with chemotherapy to treat cancer (e.g., solid tumors). For example, methods and materials for using inhibitors of IL-9 signaling (e.g., anti-IL9 antibody preparations) in conjunction with chemotherapy to treat cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) or to reduce the growth rate of cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) within a mammal are provided.
FILED Monday, October 30, 2017
APPL NO 15/797977
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101) Original (OR) Class
A61K 2039/505 (20130101)

Peptides
C07K 16/244 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166297 Gao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Guangping Gao (Westborough, Massachusetts);  Phillip D. Zamore (Northborough, Massachusetts)
ABSTRACT The invention in some aspects relates to isolated nucleic acids, compositions, and kits useful for identifying adeno-associated viruses in cells. In some aspects, the invention provides kits and methods for producing somatic transgenic animal models using recombinant AAV (rAAV) to an animal having at least one transgene that expresses a small interfering nucleic acid or at least one binding site for a miRNA.
FILED Friday, February 03, 2017
APPL NO 15/423702
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0275 (20130101)
A01K 2207/05 (20130101)
A01K 2217/058 (20130101)
A01K 2227/105 (20130101)
A01K 2267/03 (20130101)
A01K 2267/0331 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 38/00 (20130101)
A61K 48/0008 (20130101) Original (OR) Class
A61K 48/0058 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 15/8509 (20130101)
C12N 2015/8527 (20130101)
C12N 2310/13 (20130101)
C12N 2310/141 (20130101)
C12N 2320/32 (20130101)
C12N 2330/51 (20130101)
C12N 2710/10342 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14145 (20130101)
C12N 2820/002 (20130101)
C12N 2840/007 (20130101)
C12N 2840/102 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166299 Chiorini
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia)
ASSIGNEE(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPT. OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH (Washington, District of Columbia)
INVENTOR(S) John Chiorini (Dayton, Maryland)
ABSTRACT The invention relates to a gene transfer-based method to protect a subject from Sjogren's syndrome. The method comprises administering to the subject an AAV virion comprising an AAV vector that encodes aquaporin-1 (AQP-1) protein. Also provided are AQP-1 proteins and nucleic acid molecules that encode such proteins. Also provided are AAV vectors and AAV virions that encode an AQP-1 protein.
FILED Friday, August 30, 2013
APPL NO 14/423774
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/177 (20130101)
A61K 48/00 (20130101)
A61K 48/005 (20130101) Original (OR) Class

Peptides
C07K 14/47 (20130101)
C07K 14/705 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166301 Berkman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Cancer Targeted Technology (Woodinville, Washington)
ASSIGNEE(S) CANCER TARGETED TECHNOLOGY LLC (Woodinville, Washington)
INVENTOR(S) Clifford Berkman (Pullman, Washington);  Bea Langton-Webster (Woodinville, Washington);  Xiaobing Wang (Redmond, Washington)
ABSTRACT Compounds as defined herein are provided which are useful in (1) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable diluent; and (3) methods for imaging prostate cancer cells.
FILED Wednesday, January 17, 2018
APPL NO 15/873249
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/04 (20130101)
A61K 51/0489 (20130101) Original (OR) Class
A61K 51/0497 (20130101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 59/004 (20130101)
C07B 2200/05 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/2458 (20130101)
C07F 9/6515 (20130101)
C07F 9/6524 (20130101)
C07F 9/6527 (20130101)
C07F 9/6561 (20130101)
C07F 9/65583 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166379 Konofagou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Elisa E. Konofagou (New York, New York);  James J. Choi (Englewood, New Jersey)
ABSTRACT Systems and methods for opening a tissue to a target value using microbubbles are disclosed herein. In an embodiment of a method for opening a tissue to a target value using microbubbles, a region of the tissue is targeted for opening, an acoustic parameter corresponding to the target value is determined, and an ultrasound beam is applied to the target region at the acoustic parameter such that the tissue at the target region is opened to the target value with the microbubbles. The acoustic parameter can be selected to control an acoustic cavitation event and, in some embodiments, controlling an acoustic cavitation event can include controlling a location, number and/or magnitude of acoustic cavitation events.
FILED Thursday, May 26, 2016
APPL NO 15/165942
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/0071 (20130101)
A61B 8/481 (20130101)
A61B 8/0808 (20130101)
A61B 8/0816 (20130101)
A61B 17/225 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/0092 (20130101) Original (OR) Class
A61M 2202/0007 (20130101)
A61M 2205/058 (20130101)
A61M 2205/0244 (20130101)
A61M 2210/12 (20130101)
A61M 2210/0693 (20130101)
A61M 2250/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166542 Ros et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Alexandra Ros (Phoenix, Arizona);  Bahige G. Abdallah (Casa Grande, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Alexandra Ros (Phoenix, Arizona);  Bahige G. Abdallah (Casa Grande, Arizona)
ABSTRACT A microfluidic apparatus, systems and methods for microfluidic crystallization based on gradient mixing. In one embodiment, the apparatus includes (a) a first layer, (b) a plurality of first channels and a plurality of vacuum chambers both arranged in the first layer, where the plurality of vacuum chambers are each coupled to at least one of the first channels, (c) a membrane having first and second surfaces, where the first surface of the membrane is coupled to the first layer, (d) a second layer coupled to the second surface of the membrane, (e) a plurality of wells and a plurality of second channels both arranged in the second layer, where the wells are each coupled to at least one of the plurality of second channels and (f) a plurality of barrier walls each disposed in the plurality of second channels and arranged opposite to one of the plurality of vacuum chambers.
FILED Thursday, September 17, 2015
APPL NO 15/510126
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101)
B01L 3/502715 (20130101)
B01L 3/502738 (20130101)
B01L 3/502761 (20130101) Original (OR) Class
B01L 2200/0652 (20130101)
B01L 2300/16 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0654 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0848 (20130101)
B01L 2300/0861 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2300/0887 (20130101)
B01L 2300/0896 (20130101)
B01L 2400/049 (20130101)
B01L 2400/0424 (20130101)
B01L 2400/0487 (20130101)
B01L 2400/0655 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167258 Chuang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) David T. Chuang (Dallas, Texas);  Shih-Chia Tso (Carrolton, Texas);  Xiangbing Qi (Beijing, China PRC);  Wen-Jun Gui (Dallas, Texas);  Cheng-Yang Wu (Dallas, Texas);  Jacinta L. Chuang (Dallas, Texas);  Uttam K. Tambar (Dallas, Texas);  R. Max Wynn (Hurst, Texas)
ABSTRACT The present disclosure relates to the identification of PDK inhibitors and their use in the treatment of diseases such as diabetes, cardiovascular disease and cancer. The invention relates to the development of robust PDK inhibitors that can be used to improve glucose metabolism and correct metabolic dysfunction in vivo. Based on the unique structural features present in the ATP-binding pocket of PDK2, a single functional-group change was made in a known Hsp90 inhibitor that binds to the corresponding pocket of the latter protein from the GHKL family. This approach efficiently converted the Hsp90 inhibitor to a highly specific inhibitor for all PDK isoforms. These final PDK inhibitors of this series robustly augments PDC activity with reduced phosphorylation in tissues.
FILED Friday, December 12, 2014
APPL NO 15/103619
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 209/44 (20130101) Original (OR) Class
C07D 401/06 (20130101)
C07D 401/12 (20130101)
C07D 401/14 (20130101)
C07D 487/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167260 Silverman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Richard B. Silverman (Winnetka, Illinois);  Qing Jing (Morton Grove, Illinois)
ABSTRACT Aminopyridine compounds, as can be used in conjunction with methods for modulation of nitric oxide synthase activity.
FILED Friday, June 30, 2017
APPL NO 15/639824
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 213/73 (20130101) Original (OR) Class
C07D 401/12 (20130101)
C07D 401/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167265 Reddy
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Raju Reddy (Cheswick, Pennsylvania)
ABSTRACT Disclosed is a compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of:
X1-L-X2 wherein L is a linking moiety comprising an enone; and X1 and X2 are each independently an optionally-substituted N-heterocycle. Also disclosed are method for treating pulmonary conditions and other organ or system conditions with the compounds.
FILED Thursday, November 30, 2017
APPL NO 15/828163
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 239/26 (20130101)
C07D 239/30 (20130101)
C07D 239/34 (20130101)
C07D 239/38 (20130101)
C07D 239/42 (20130101)
C07D 239/47 (20130101)
C07D 239/52 (20130101)
C07D 241/12 (20130101)
C07D 241/16 (20130101)
C07D 241/18 (20130101)
C07D 241/20 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167277 Tsai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Li-Huei Tsai (Cambridge, Massachusetts);  Ling Pan (Charlestown, Massachusetts);  Stephen J. Haggarty (Gloucester, Massachusetts);  Debasis Patnaik (Weymouth, Massachusetts)
ABSTRACT The present invention provides compounds of Formulae (A), (B), (C), and (D), pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof, pharmaceutical compositions thereof, and kits thereof. The present invention further provides methods of using the compounds to treat or prevent neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, ALS (amyotrophic lateral sclerosis), traumatic brain injury, ischemic brain injury, stroke, frontal temporal dementia, Pick's disease, corticobasal degeneration, supra cerebral palsy, prion diseases (e.g., Creutzfeldt-Jakob disease, Gerstmann-Straussler-Scheinker syndrome, Fatal Familial Insomnia, and Kuru), Nieman Pick type C, spinal cerebellar ataxia, spinal muscular dystrophy, ataxia telangiectasia, hippocampal sclerosis, Cockayne syndrome, Werner syndrome, xeroderma pigmentosaum, and Bloom syndrome. In one aspect, the methods include administering to a subject in need of treatment for a neurological disorder a therapeutically effective amount of DAC-001, DAC-002, DAC-003, DAC-009, or DAC-012, or a compound of Formula (A), (B), (C), or (D).
FILED Tuesday, August 25, 2015
APPL NO 14/834587
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 217/58 (20130101)
C07C 219/28 (20130101)

Heterocyclic Compounds
C07D 307/40 (20130101)
C07D 307/52 (20130101)
C07D 405/12 (20130101) Original (OR) Class
C07D 409/12 (20130101)
C07D 411/12 (20130101)
C07D 487/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167287 Gangjee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania);  Wayne State University (Detroit, Michigan)
ASSIGNEE(S) Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania)
INVENTOR(S) Aleem Gangjee (Allison Park, Pennsylvania);  Larry H. Matherly (Novi, Michigan)
ABSTRACT This invention provides substituted pyrimidine compounds having the formula:
wherein X is absent, CH2, S, or O, and R is an alkyl group having from one to ten carbon atoms, and optionally salts, hydrates, or solvates thereof, that are useful in treating a patient having a disease or cancer. The compounds of this invention are useful as multi-enzyme antifolates selectively targeting the folate receptor (FR). Further, a method of making 5- and 6-substituted cyclopenta[d]pyrimidine for nonclassical and classical antifolates as TS and DHFR inhibitors is provided.
FILED Wednesday, April 05, 2017
APPL NO 15/479938
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 239/70 (20130101)
C07D 487/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167295 Levine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jon D. Levine (San Francisco, California);  Alejandra Gallardo-Godoy (Brisbane, Australia)
ABSTRACT Provided herein, inter alia, are methods and compositions for achieving an analgesic effect in subjects in need thereof.
FILED Friday, September 11, 2015
APPL NO 14/851248
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 207/06 (20130101)
C07D 207/09 (20130101)
C07D 207/263 (20130101)
C07D 211/06 (20130101)
C07D 211/12 (20130101)
C07D 401/06 (20130101)
C07D 403/12 (20130101)
C07D 405/12 (20130101)
C07D 405/14 (20130101)
C07D 489/00 (20130101)
C07D 489/02 (20130101)
C07D 491/107 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167311 Caligiuri et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Michael Caligiuri (Columbus, Ohio);  Robert Lee (Columbus, Ohio);  Guido Marcucci (Columbus, Ohio)
ABSTRACT Provided herein are boronic acid esters of boronic acid therapeutic agents, such as bortezomib. The boronic acid esters can be used to prepare liposomal formulations of boronic acid therapeutic agents with improved properties, such as enhanced stability. This disclosure, in one aspect, relates to compositions and methods of making and using the compositions.
FILED Tuesday, February 03, 2015
APPL NO 15/116312
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 38/05 (20130101)
A61K 47/543 (20170801)
A61K 47/544 (20170801)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/04 (20130101)

Peptides
C07K 5/06191 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167315 Servoss et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas);  UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas);  UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina)
INVENTOR(S) Shannon Servoss (Fayetteville, Arkansas);  Melissa Moss (Columbia, South Carolina);  James Phillip Turner, Jr. (Fayetteville, Arkansas)
ABSTRACT Provided herein are peptoids capable of inhibiting or reversing amyloid β (Aβ) fibril or plaque production. The peptoids form a helical structure with three monomers per helical turn and have at least four monomers with a side-chain having an arylalkyl or aryl group. The peptoid may be achiral. Also provided are methods of using the peptoids to inhibit or reverse aggregation of Aβ and methods of treating subjects with Alzheimer's disease (AD) or slowing the progression of AD.
FILED Friday, June 24, 2016
APPL NO 15/191925
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 7/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167326 Andersen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) ALBANY MEDICAL COLLEGE (Albany, New York)
ASSIGNEE(S) ALBANY MEDICAL COLLEGE (Albany, New York)
INVENTOR(S) Thomas T. Andersen (Albany, New York);  Herbert I. Jacobson (Albany, New York);  James A. Bennett (Delmar, New York);  Leroy Joseph (Brooklyn, New York);  Alberto Bryan (Philadelphia, Pennsylvania)
ABSTRACT The invention relates to compounds that are analogs of a cyclic peptide, cyclo[EKTOVNOGN], AFPep, that has anti-estrotrophic activity. The analogs of the invention include peptides and peptidomimetics that inhibit estrogen receptor-dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwanted estrogen induced cell proliferation, including breast cancer.
FILED Friday, January 29, 2016
APPL NO 15/010724
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 7/52 (20130101)
C07K 7/64 (20130101)
C07K 14/4715 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167328 Fu
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Yang-Xin Fu (Chicago, Illinois)
ABSTRACT Methods and compositions are disclosed to target tumor cells with embodiments of the LIGHT proteins linked fused or conjugated to a targeting agent. These compositions bind to both human and mouse receptors with affinity sufficient to conduct preclinical and clinical trials, and with increased affinity as compared to the wild type human LIGHT protein. The targeting of embodiments of LIGHT to tumor cells reduces tumor growth and reduces metastases.
FILED Wednesday, November 02, 2016
APPL NO 15/341678
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 38/191 (20130101)
A61K 45/06 (20130101)
A61K 47/6803 (20170801)
A61K 47/6813 (20170801)
A61K 47/6851 (20170801)
A61K 47/6855 (20170801)
A61K 47/6863 (20170801)

Peptides
C07K 14/525 (20130101) Original (OR) Class
C07K 14/625 (20130101)
C07K 16/32 (20130101)
C07K 16/46 (20130101)
C07K 16/2863 (20130101)
C07K 16/3015 (20130101)
C07K 16/3046 (20130101)
C07K 2317/14 (20130101)
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)
C07K 2317/622 (20130101)
C07K 2319/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167330 Herrin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Emory University (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Brantley R. Herrin (Decatur, Georgia);  Max Dale Cooper (Atlanta, Georgia);  Rudolf Ehrhardt (Decatur, Georgia)
ABSTRACT This disclosure relates to variable lymphocyte receptors (VLRs) modifications such as humanized sequences and polypeptides comprising such sequences that specifically bind a target molecule and uses related thereto. In certain embodiments, the disclosure relates to recombinant polypeptide VLRs disclosed herein and variants thereof. In certain embodiments, this disclosure relates to treating or preventing a disease or condition comprising administering an effective amount of a recombinant polypeptide or variant disclosed herein to a subject in need thereof.
FILED Thursday, April 30, 2015
APPL NO 15/308535
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/7051 (20130101) Original (OR) Class
C07K 2319/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167332 Ravetch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Jeffrey V. Ravetch (New York, New York);  Yoshikatsu Kaneko (Niigata, Japan);  Nimmerjahn Falk (Erlangen, Germany)
ASSIGNEE(S) The Rockefeller University (New York, New York)
INVENTOR(S) Jeffrey V. Ravetch (New York, New York);  Yoshikatsu Kaneko (Niigata, Japan);  Nimmerjahn Falk (Erlangen, Germany)
ABSTRACT The invention provides a polypeptide containing at least one IgG Fc region region, said polypeptide having a higher anti-inflammatory activity and a lower cytotoxic activity as compared to an unpurified antibody and methods of production of such polypeptide.
FILED Tuesday, April 03, 2007
APPL NO 12/294883
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/68 (20170801)
A61K 2039/505 (20130101)

Peptides
C07K 16/00 (20130101) Original (OR) Class
C07K 16/06 (20130101)
C07K 16/18 (20130101)
C07K 2317/41 (20130101)
C07K 2317/52 (20130101)
C07K 2317/71 (20130101)
C07K 2317/76 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/005 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6854 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167334 Mirza et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) XOMA TECHNOLOGY LTD. (Berkeley, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) XOMA TECHNOLOGY LTD. (Berkeley, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Amer M. Mirza (San Francisco, California);  Rosemary J. Akhurst (Tiburon, California);  Ou Li (San Francisco, California)
ABSTRACT The present disclosure relates, in general, to combination therapy using an inhibitor of transforming growth factor beta (TGFβ) and an inhibitor of programmed cell death protein 1 (PD-1) for treating cancer or preventing recurrence of cancer diseases such as lung cancer, prostate cancer, breast cancer, hepatocellular cancer, esophageal cancer, colorectal cancer, pancreatic cancer, bladder cancer, kidney cancer, ovarian cancer, stomach cancer, fibrotic cancer, glioma and melanoma, and metastases thereof.
FILED Sunday, April 03, 2016
APPL NO 15/089579
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/57 (20130101)
A61K 2039/507 (20130101)

Peptides
C07K 16/22 (20130101) Original (OR) Class
C07K 16/2803 (20130101)
C07K 16/2818 (20130101)
C07K 2317/51 (20130101)
C07K 2317/56 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/515 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167339 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) BAYLOR RESEARCH INSTITUTE (Dallas, Texas)
ASSIGNEE(S) Baylor Research Institute (Dallas, Texas)
INVENTOR(S) Yong-Jun Liu (Gaithersburg, Maryland);  Sandra Zurawski (Midlothian, Texas);  SangKon Oh (Baltimore, Maryland);  Shino Hanabuchi (Gaithersburg, Maryland);  Haruyuki Fujita (Gaithersburg, Maryland);  Hideki Ueno (Plano, Texas);  Patrick Blanco (Verdelais, France);  Hyemee Joo (Dallas, Texas)
ABSTRACT Described herein are methods and compositions for treating autoimmunity and inflammatory conditions without non-specific suppression of the host immune system. In particular, the anti-OX40L antibodies described herein are unique in that they not only inhibit the differentiation of inflammatory T cells but also promote the generation and function of regulatory T cells by inducing IL-10 and inhibiting TNF-α and by reducing aberrant Th2 cell responses. Furthermore, the methods and compositions described herein eliminate or reduce aberrant T follicular helper cell—(Tfh) responses that may contribute to the pathogenicity of autoimmune disease.
FILED Monday, August 03, 2015
APPL NO 15/501526
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)
A61K 2039/545 (20130101)

Peptides
C07K 16/2875 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167454 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Child Health and Human Development (NICHD)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Lili Wang (Phoenixville, Pennsylvania);  James M. Wilson (Glen Mills, Pennsylvania)
ABSTRACT Viral vectors comprising engineered hOTC DNA and RNA sequences are provided which when delivered to a subject in need thereof are useful for treating hyperammonemia, ornithine transcarbamylase deficiency and symptoms associated therewith. Also provided are methods of using hOTC for treatment of liver fibrosis cirrhosis in OTCD patients by administering hOTC.
FILED Monday, March 09, 2015
APPL NO 15/122853
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/0058 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1018 (20130101) Original (OR) Class
C12N 15/86 (20130101)
C12N 2710/10343 (20130101)
C12N 2740/15043 (20130101)
C12N 2750/14032 (20130101)
C12N 2750/14033 (20130101)
C12N 2750/14043 (20130101)
C12N 2750/14071 (20130101)
C12N 2750/14143 (20130101)
C12N 2800/22 (20130101)

Enzymes
C12Y 201/03003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167457 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David R. Liu (Lexington, Massachusetts);  Alexis Christine Komor (Pasadena, California);  Holly A. Rees (Cambridge, Massachusetts);  Yongjoo Kim (Cambridge, Massachusetts)
ABSTRACT Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins of Cas9 and nucleic acid editing proteins or protein domains, e.g., deaminase domains, are provided. In some embodiments, methods for targeted nucleic acid editing are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of Cas9 and nucleic acid editing proteins or domains, are provided.
FILED Saturday, October 22, 2016
APPL NO 15/331852
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/32 (20130101)
C07K 2319/00 (20130101)
C07K 2319/09 (20130101)
C07K 2319/80 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101) Original (OR) Class
C12N 9/78 (20130101)
C12N 9/2497 (20130101)
C12N 15/907 (20130101)

Enzymes
C12Y 305/04005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167469 Merbl et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Yifat Merbl (Boston, Massachusetts);  Marc W. Kirschner (Newton, Massachusetts)
ABSTRACT Described herein are methods of inhibiting mitosis, treating cancer and/or treating immune disorders through the use of agents that inhibit FAT10 and/or the FAT10 pathway.
FILED Thursday, March 30, 2017
APPL NO 15/474320
ART UNIT 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0276 (20130101)
A01K 2217/075 (20130101)
A01K 2227/105 (20130101)
A01K 2267/0331 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 31/7105 (20130101)

Peptides
C07K 14/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)
C12N 2320/30 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/68 (20130101)
G01N 33/5011 (20130101)
G01N 2333/70539 (20130101)
G01N 2500/02 (20130101)
G01N 2800/24 (20130101)
G01N 2800/7028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167474 Rossi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) City of Hope (Duarte, California);  The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) City of Hope (Duarte, California);  The Scripps Research Institute (La Jolla, California)
INVENTOR(S) John Rossi (Alta Loma, California);  Jiehua Zhou (Monrovia, California);  Marc Weinberg (Encinitas, California);  Kevin Morris (Sierra Madre, California)
ABSTRACT Provided herein are fluoropyrimidine-modified RNA aptamers capable of binding CCR5. The compositions and methods provided herein are, inter alia, useful for the delivery of antiviral drugs (e.g., siRNAs) and preventing HIV entry into a target cell.
FILED Friday, March 24, 2017
APPL NO 15/469320
ART UNIT 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/115 (20130101) Original (OR) Class
C12N 2310/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167478 Williams
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Nature Technology Corporation (Lincoln, Nebraska)
ASSIGNEE(S) Nature Technology Corporation (Lincoln, Nebraska)
INVENTOR(S) James A. Williams (Lincoln, Nebraska)
ABSTRACT The present invention relates to the production and use of covalently closed circular (ccc) recombinant DNA molecules such as plasmids, cosmids, bacterial artificial chromosomes (BACs), bacteriophages, viral vectors and hybrids thereof, and more particularly to vector modifications that improve expression of said DNA molecules.
FILED Tuesday, April 12, 2016
APPL NO 15/096517
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/63 (20130101)
C12N 15/64 (20130101)
C12N 15/67 (20130101)
C12N 15/79 (20130101) Original (OR) Class
C12N 15/85 (20130101)
C12N 2800/24 (20130101)
C12N 2800/107 (20130101)
C12N 2820/55 (20130101)
C12N 2830/42 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)
C12P 21/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167485 Chamberlain et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Jeffrey S. Chamberlain (Seattle, Washington);  Dennis J. Hartigan-O'Connor (Ann Arbor, Michigan)
ABSTRACT The present invention relates to methods and compositions for the production of viral vectors. In particular, the present invention provides methods and compositions for faster, higher titer and higher purity production of viral vectors (e.g. adenoviral vectors). In some embodiments, the present invention provides gutted and helper viruses with identical or similar termini. In other embodiments, the present invention provides terminal protein linked adenoviral DNA. In certain embodiments, the present invention provides template extended adenoviral DNA.
FILED Friday, August 12, 2016
APPL NO 15/236205
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101) Original (OR) Class
C12N 2710/10043 (20130101)
C12N 2710/10322 (20130101)
C12N 2710/10343 (20130101)
C12N 2710/10351 (20130101)
C12N 2800/30 (20130101)
C12N 2830/002 (20130101)
C12N 2830/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167488 Keasling et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jay D. Keasling (Berkeley, California);  Christopher B. Eiben (Berkeley, California)
ABSTRACT Cells comprising a heterologous metabolic pathway are configured to produce a terpene product containing non-multiples of five carbon, particularly wherein the pathway comprises heterologous Lepidoptera insect juvenile hormone biosynthetic pathway enzymes of the insect's mevalonate pathway.
FILED Friday, November 03, 2017
APPL NO 15/803735
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0006 (20130101)
C12N 9/88 (20130101)
C12N 9/90 (20130101)
C12N 9/1025 (20130101)
C12N 9/1029 (20130101)
C12N 9/1085 (20130101)
C12N 9/1205 (20130101)
C12N 15/52 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 5/007 (20130101) Original (OR) Class
C12P 9/00 (20130101)

Enzymes
C12Y 101/01034 (20130101)
C12Y 203/0301 (20130101)
C12Y 203/01009 (20130101)
C12Y 205/01001 (20130101)
C12Y 207/01036 (20130101)
C12Y 402/03027 (20130101)
C12Y 503/03002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167490 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Pinghua Liu (Newton, Massachusetts);  Heng Song (Allston, Massachusetts);  Wen Hu (Boston, Massachusetts)
ASSIGNEE(S) Ergo Health LLC (Newton, Massachusetts)
INVENTOR(S) Pinghua Liu (Newton, Massachusetts);  Heng Song (Allston, Massachusetts);  Wen Hu (Boston, Massachusetts)
ABSTRACT The present disclosure relates to the production of ergothioneine through either in vitro enzymatic transformations or fermentations using microbials created by metabolic engineering. Also disclosed are transformed cells useful in such methods and ergothioneine produced by such methods. Transformed cells of the disclosure are capable of converting histidine and cysteine or hercynine and cysteine into ergothioneine in greater efficiency than the untransformed wild-type cells.
FILED Friday, December 20, 2013
APPL NO 14/428061
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Heterocyclic Compounds
C07D 233/42 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/52 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 13/04 (20130101)
C12P 17/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167506 Ronaghi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) ILLUMINA, INC. (San Diego, California)
ASSIGNEE(S) Illumina, Inc. (San Diego, California)
INVENTOR(S) Mostafa Ronaghi (San Diego, California);  Helmy A. Eltoukhy (Atherton, California)
ABSTRACT A method of sequencing nucleic acids, which can include steps of contacting a substrate having spatially distinguishable features with a plurality of nucleic acids to seed a subset of the features, thereby generating a seeded subset; amplifying the nucleic acids in the seeded subset to form nucleic acid colonies; repeating the preceding steps to increase the number of seeded features, thereby generating an array of nucleic acid colonies; and sequencing the array of nucleic acid colonies.
FILED Monday, October 02, 2017
APPL NO 15/722500
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6837 (20130101)
C12Q 1/6837 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6874 (20130101) Original (OR) Class
C12Q 1/6874 (20130101)
C12Q 2535/122 (20130101)
C12Q 2565/543 (20130101)
C12Q 2565/543 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167510 Ozelius et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Icahn School of Medicine of Mount Sinai (New York, New York)
ASSIGNEE(S) Icahn School of Medicine at Mount Sinai (New York, New York)
INVENTOR(S) Laurie Ozelius (White Plains, New York);  Susan Bressman (New York, New York)
ABSTRACT The invention relates generally to the THAP1 gene and mutations in this gene, as well as the THAP1 protein and mutations in this protein, that are associated with dystonia. The invention relates to the identification, isolation, cloning and characterization of the DNA sequence corresponding to the wild type and mutant THAP1 genes, as well as isolation and characterization of their transcripts and gene products. The invention further relates to methods and kits useful for detecting mutations in THAP1 that are associated with dystonia, as well as to methods and kits useful for diagnosing dystonia. The present invention also relates to therapies for treating dystonia, including gene therapeutics and protein/antibody based therapeutics.
FILED Thursday, March 17, 2016
APPL NO 15/072686
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/47 (20130101)
C07K 14/4747 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)
C12Q 2600/172 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167512 Nagarkatti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Complementary and Integrative Health (NCCIH)
APPLICANT(S) University of South Carolina (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Mitzi Nagarkatti (Columbia, South Carolina);  Juhua Zhou (Lexington, South Carolina);  Bruce A. Lessey (Greenville, South Carolina);  Prakash Nagarkatti (Columbia, South Carolina)
ABSTRACT Methods for diagnosis and treatment of endometriosis are described. Methods utilize the recognition that leukocyte miRNAs can be dramatically dysregulated subjects suffering from endometriosis. Accordingly, leukocyte miRNAs, as well as polynucleotides encoding the miRNAs, can be utilized in the diagnosis and treatment of endometriosis.
FILED Thursday, May 11, 2017
APPL NO 15/592428
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/158 (20130101)
C12Q 2600/178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167513 Ahuja et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Nita Ahuja (Lutherville, Maryland);  Stephen Baylin (Baltimore, Maryland);  James G. Herman (Lutherville, Maryland);  Jeff Wang (Timonium, Maryland);  Vasudev Bailey (Baltimore, Maryland);  Mi J. Yi (Laurel, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Nita Ahuja (Lutherville, Maryland);  Stephen Baylin (Baltimore, Maryland);  James G. Herman (Lutherville, Maryland);  Jeff Wang (Timonium, Maryland);  Vasudev Bailey (Baltimore, Maryland);  Mi J. Yi (Laurel, Maryland)
ABSTRACT The invention provides compositions and methods for detecting a neoplasia (e.g., pancreatic cancer, lung cancer, colon cancer) in a subject sample (e.g., serum, blood, plasma, tissue). In particular embodiments, the invention provides methods for detecting BNC1 and ADAMTS1 promoter methylation in circulating DNA in serum.
FILED Wednesday, May 25, 2011
APPL NO 13/699452
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/154 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57407 (20130101)
G01N 33/57419 (20130101)
G01N 33/57423 (20130101)
G01N 33/57438 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167514 Newman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Aaron M. Newman (Palo Alto, California);  Arash Ash Alizadeh (San Mateo, California)
ABSTRACT Methods of deconvolving a feature profile of a physical system are provided herein. The present method may include: optimizing a regression between a) a feature profile of a first plurality of distinct components and b) a reference matrix of feature signatures for a second plurality of distinct components, wherein the feature profile is modeled as a linear combination of the reference matrix, and wherein the optimizing includes solving a set of regression coefficients of the regression, wherein the solution minimizes 1) a linear loss function and 2) an L2-norm penalty function; and estimating the fractional representation of one or more distinct components among the second plurality of distinct components present in the sample based on the set of regression coefficients. Systems and computer readable media for performing the subject methods are also provided.
FILED Friday, January 22, 2016
APPL NO 15/004611
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6809 (20130101)
C12Q 1/6809 (20130101)
C12Q 1/6881 (20130101)
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2537/165 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5005 (20130101)

Electric Digital Data Processing
G06F 19/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167515 Park et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Seung-min Park (Menlo Park, California);  Dawson Wong (San Jose, California);  Chin Chun Ooi (Menlo Park, California);  Sanjiv Sam Gambhir (Portola Valley, California);  Viswam S. Nair (Menlo Park, California);  Shan X. Wang (Portola Valley, California)
ABSTRACT A method for identification of circulating tumor cells (CTCs) in a blood sample uses magnetic enrichment and a nanowell assay. The CTCs are magnetically labeled with cancer cell markers conjugated to magnetic nanoparticles and then separated by passing the blood sample through a magnetic sifter. The enriched CTCs are then loaded into a microfluidic single-cell molecular assay comprising an array of 25,600 or more nanowells, each containing at most a single one of the CTCs. Using multiple fluorescent gene markers, simultaneous multiple-color multiplexed gene expression of the CTCs is performed, preferably using RT-PCR. Images of fluorescence signals from individual nanowells are analyzed to identify CTCs.
FILED Wednesday, April 20, 2016
APPL NO 15/133996
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/686 (20130101)
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2521/107 (20130101)
C12Q 2537/143 (20130101)
C12Q 2600/158 (20130101)

Electric Digital Data Processing
G06F 17/30132 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167516 Newton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin);  The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Christina Kendziorski Newton (Madison, Wisconsin);  Kevin Hasegawa Eng (Williamsville, New York);  Janet S. Rader (Whitefish Bay, Wisconsin);  William H. Bradley (Wauwatosa, Wisconsin)
ABSTRACT Described herein are methods of predicting the risk of developing ovarian cancer recurrence of a subject comprising the steps of detecting the expression levels of at least four of the six genes selected from the group consisting of AKT2, KRAS, RAC1, CALM3, RPS6KA2 and YWHAB or the gene products thereof, wherein the presence of increased expression levels of the genes or the gene products is predictive of the increased risk of developing ovarian cancer recurrence in the subject. Kits for practicing the methods are also disclosed.
FILED Monday, October 31, 2016
APPL NO 15/339109
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/138 (20130101)
A61K 31/337 (20130101)
A61K 31/519 (20130101)
A61K 31/704 (20130101)
A61K 31/4745 (20130101)
A61K 31/7068 (20130101)
A61K 33/24 (20130101)
A61K 39/3955 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/118 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)
C12Q 2600/178 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57449 (20130101)
G01N 2800/50 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167517 Chinnaiyan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Arul M. Chinnaiyan (Plymouth, Michigan);  Scott Tomlins (Ann Arbor, Michigan);  Saravana Mohan Dhanasekaran (Ann Arbor, Michigan)
ABSTRACT Compositions and methods associated with recurrent MIPOL1-ETV1 genetic rearrangements that are useful for cancer diagnosis and therapy are disclosed.
FILED Friday, June 30, 2017
APPL NO 15/639583
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/118 (20130101)
C12Q 2600/136 (20130101)
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167519 Luo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Jianhua Luo (Wexford, Pennsylvania);  Yangping Yu (Wexford, Pennsylvania);  Joel B. Nelson (Pittsburgh, Pennsylvania);  George Konstantine Michalopoulos (Pittsburgh, Pennsylvania);  Chien-Cheng Tseng (Pittsburgh, Pennsylvania);  Ying Ding (San Diego, California)
ABSTRACT The present invention relates to methods and compositions for determining whether a subject having prostate cancer is at greater risk of developing progressive disease, and methods of treating the subjects. It is based, at least in part, on the discovery that approximately 90% of men carrying at least one of the following fusion genes: TRMT11-GRIK2, SLC45A2-AMACR, MTOR-TP53BP1, LRRC59-FLJ60017, TMEM135-CCDC67 and CCNH-05orf30 experienced prostate cancer recurrence, metastases and/or prostate cancer-specific death after radical prostatectomy (each examples of “progressive prostate cancer”), while these outcomes occurred in only 36% of men not carrying any of these fusion genes. It is also based, at least in part, on the discovery that no patient studied survived five years without recurrence if their primary prostate cancer contained a TRMT11-GRIK2 or MTOR-TP53BP1 fusion gene. It is also based, at least in part, on the discovery that the protein encoded by the MAN2A1-FER fusion gene exhibits kinase activity.
FILED Wednesday, February 14, 2018
APPL NO 15/896818
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168317 Mak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Michael Mak (Boston, Massachusetts);  David Erickson (Ithaca, New York)
ABSTRACT The present invention relates to a microfluidic device, a microfluidic system, and methods for tracking single cells, multiple cells, single cell lineages, and multiple cell lineages in series and/or in parallel. The microfluidic device comprises a substrate having one microfluidic channel formed therein or a plurality of microfluidic channels formed therein and arranged in parallel. The microfluidic system comprises: a microfluidic device according to the present invention; a cell loading reservoir in fluid communication with the inlet end of each microfluidic channel of the microfluidic device; and an outlet reservoir in fluid communication with the outlet end of each microfluidic channel of the microfluidic device. The present invention also relates to a high throughput microfluidic system and a kit for tracking single cells and/or single cell lineages.
FILED Monday, June 10, 2013
APPL NO 14/406310
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502761 (20130101)
B01L 2200/0668 (20130101)
B01L 2300/087 (20130101)
B01L 2300/0861 (20130101)
B01L 2400/086 (20130101)
B01L 2400/0457 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
G01N 33/5005 (20130101) Original (OR) Class
G01N 33/5008 (20130101)
G01N 2500/10 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168337 Brasier et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Allan Brasier (Galveston, Texas);  Adrian Recinos (Galveston, Texas);  John E. Wiktorowicz (League City, Texas);  Heidi Spratt (Galveston, Texas);  Hyunsu Ju (League City, Texas);  Nikos Vasilakis (Galveston, Texas);  Ernesto E. T. Marquez (Pittsburgh, Pennsylvania);  Marli Tenorio (Recife, Brazil);  Laura H. V. G. Gil (Recife, Brazil);  Eduardo Nascimento (Allentown, Pennsylvania)
ASSIGNEE(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Allan Brasier (Galveston, Texas);  Adrian Recinos (Galveston, Texas);  John E. Wiktorowicz (League City, Texas);  Heidi Spratt (Galveston, Texas);  Hyunsu Ju (League City, Texas);  Nikos Vasilakis (Galveston, Texas);  Ernesto E. T. Marquez (Pittsburgh, Pennsylvania);  Marli Tenorio (Recife, Brazil);  Laura H. V. G. Gil (Recife, Brazil);  Eduardo Nascimento (Allentown, Pennsylvania)
ABSTRACT The present invention provides compositions and methods for detecting, analyzing, and identifying biomolecules used to diagnose patient with risk of DHF. More particularly, the invention provides plasma biomarkers including complement factor D to complement factor H (FactorD/FactorH) ratio and levels of one or more of IL2, desmoplakin, and high molecular weight albumin, which are used to detect risk of developing DHF.
FILED Wednesday, June 06, 2012
APPL NO 14/124343
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/564 (20130101)
G01N 33/6851 (20130101)
G01N 33/6869 (20130101) Original (OR) Class
G01N 33/56983 (20130101)
G01N 2333/47 (20130101)
G01N 2333/55 (20130101)
G01N 2333/76 (20130101)
G01N 2333/185 (20130101)
G01N 2333/4716 (20130101)
G01N 2333/5428 (20130101)
G01N 2800/26 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/53 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168338 Sabatini et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Congressionally Directed Medical Research Programs (CDMRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S) David M. Sabatini (Cambridge, Massachusetts);  Lynne Chantranupong (Cambridge, Massachusetts);  Rachel L. Wolfson (Cambridge, Massachusetts);  Jose Orozco (Boston, Massachusetts);  Robert A. Saxton (Cambridge, Massachusetts);  Shomit Sengupta (Belmont, Massachusetts)
ABSTRACT The present invention provides methods of identifying modulators of mTORC1 based upon their effect on GATOR2-Sestrin binding or Sestrin-leucine binding; and the use of such modulators to alter mTORC1 activity in a cell and to treat disease and conditions that are effected by mTORC1 activity.
FILED Friday, September 11, 2015
APPL NO 15/511007
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
G01N 33/5041 (20130101)
G01N 33/6872 (20130101) Original (OR) Class
G01N 2500/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168342 Cravatt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Benjamin F. Cravatt (La Jolla, California);  Micah J. Niphakis (San Diego, California);  Kenneth Lum (San Diego, California);  Bruno Correia (Bremblens, Switzerland);  Armand Cognetta (San Diego, California);  Jonathan Hulce (Libertyville, Illinois)
ABSTRACT Disclosed herein are methods, compositions, probes, assays and kits for identifying a lipid binding protein as a drug binding target. Also disclosed herein are methods, compositions, and probes for mapping a ligand binding site on a lipid binding protein, identification of lipid binding proteins, generating drug-lipid binding protein profiles, high throughput drug screening, and identification of drugs as potential lipid binding protein ligands.
FILED Friday, March 25, 2016
APPL NO 15/080767
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/92 (20130101) Original (OR) Class
G01N 33/6842 (20130101)
G01N 2500/04 (20130101)
G01N 2570/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168410 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Nan-kuei Chen (Cary, North Carolina);  Trong-Kha Truong (Durham, North Carolina);  Allen W. Song (Chapel Hill, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Nan-kuei Chen (Cary, North Carolina);  Trong-Kha Truong (Durham, North Carolina);  Allen W. Song (Chapel Hill, North Carolina)
ABSTRACT Methods, systems, computer programs, circuits and workstations are configured to generate MRI images using gradient blips for signal acquisition and reconstruction using dynamic field mapping, TE corrections and/or multischeme partial Fourier images.
FILED Tuesday, December 20, 2011
APPL NO 13/992537
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/561 (20130101)
G01R 33/583 (20130101) Original (OR) Class
G01R 33/5616 (20130101)
G01R 33/56341 (20130101)
G01R 33/56518 (20130101)
G01R 33/56536 (20130101)
G01R 33/56554 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168525 Kim et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Jinho Kim (Pasadena, California);  Changhuei Yang (Alhambra, California)
ABSTRACT Certain aspects pertain to multi-well systems, devices, and methods of Fourier ptychographic and fluorescence imaging.
FILED Tuesday, January 26, 2016
APPL NO 15/007159
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6452 (20130101)
G01N 21/6456 (20130101)
G01N 21/6458 (20130101)
G01N 2021/6478 (20130101)
G01N 2201/0446 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/16 (20130101)
G02B 21/0076 (20130101)
G02B 21/365 (20130101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 5/2258 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 10165817 Redpath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) David Redpath (Beaconsfield, Canada);  Marie-Pierre Gendron (Mercier, Canada);  Stéphane Lebel (St. Redempteur, Canada)
ASSIGNEE(S) Revision Military S.a.r.l. (Luxembourg, Luxembourg)
INVENTOR(S) David Redpath (Beaconsfield, Canada);  Marie-Pierre Gendron (Mercier, Canada);  Stéphane Lebel (St. Redempteur, Canada)
ABSTRACT Methods and devices for attaching a battery to a helmet and attaching a battery to an additional device are disclosed. A battery may be mounted to the rear center of a helmet. Attaching and detaching a battery to and from a helmet may be performed with a tool or by hand. The battery may be used to power multiple devices through separate contacts, and a device may be attached to the battery while the battery mounted to a helmet. The battery also may be detached from the helmet and serve as a portable energy source.
FILED Thursday, June 28, 2012
APPL NO 13/536980
ART UNIT 3765 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Hats; Head Coverings
A42B 3/04 (20130101)
A42B 3/0406 (20130101) Original (OR) Class

Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 1/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166310 Brown et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) AEROCLAVE, LLC (Winter Park, Florida)
ASSIGNEE(S) AEROCLAVE, LLC (Winter Park, Florida)
INVENTOR(S) Ronald D. Brown (Maitland, Florida);  Paul M. Gray (Ocoee, Florida);  James S. Amrhein (Oviedo, Florida)
ABSTRACT A decontamination system (10), including: a plurality of interconnected and insulated panels (18) configured to form walls (14) and a roof (16) and to define an interior (24) of an enclosure (12) configured to enclose a transportation asset; a humidifying module (30) in fluid communication with the interior of the enclosure and configured to raise a temperature and a humidity of the interior of the enclosure to a predetermined temperature level and a predetermined humidity level for a timed duration; and a dehumidifying module (50) in fluid communication with the interior of the enclosure and configured to lower the temperature and the humidity of the interior of the enclosure from the predetermined temperature level and the predetermined humidity level to ambient levels.
FILED Tuesday, October 13, 2015
APPL NO 14/881285
ART UNIT 1799 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/22 (20130101) Original (OR) Class
A61L 2/24 (20130101)
A61L 2/208 (20130101)
A61L 2202/25 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167090 Brookhart et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aviation Applied Technology Directorate (AATD)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Andrew Brookhart (Wallingford, Connecticut);  Raymond J. Beale, Jr. (Stratford, Connecticut);  Matthew Harrigan (Horseheads, New York)
ABSTRACT A method of monitoring usage to determine accumulated component fatigue damage includes evaluating available data for calculating an accumulated component fatigue damage for a component over a pre-determined time frame. The method includes determining at least one available method for calculating the accumulated component fatigue damage based on the available data. The method includes determining the accumulated component fatigue damage for the component using the at least one available method.
FILED Wednesday, November 23, 2016
APPL NO 15/359667
ART UNIT 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 45/00 (20130101) Original (OR) Class
B64D 2045/0085 (20130101)

Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for
B64F 5/0045 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 5/0033 (20130101)
G01M 17/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 3/02 (20130101)

Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 5/085 (20130101)
G07C 5/0808 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167192 In et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Hyun Jin In (Alexandria, Virginia);  Christopher Field (Arlington, Virginia);  Pehr E. Pehrsson (Fairfax Station, Virginia)
ABSTRACT Disclosed herein is a structure having: a support, a plurality of nanowires perpendicular to the support, and an electrode in contact with a first end of each nanowire. Each nanowire has a second end in contact with the support. The electrode contains a plurality of perforations. The electrode contains a plurality of perforations. Also disclosed herein is a method of: providing the above support and nanowires; depositing a layer of a filler material that covers a portion of each nanowire and leaves a first end of each nanowire exposed; depositing a plurality of nanoparticles onto the filler material; depositing an electrode material on the nanoparticles, the ends of the nanowires, and any exposed filler material; and removing the nanoparticles and filler material to form an electrode in contact with the first end of each nanowire; wherein the electrode contains a plurality of perforations.
FILED Monday, February 22, 2016
APPL NO 15/049404
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101) Original (OR) Class
B82Y 15/00 (20130101)
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/127 (20130101)
G01N 27/4146 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 1/06744 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/456 (20130101)
H01L 29/0665 (20130101)
H01L 29/0676 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167326 Andersen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) ALBANY MEDICAL COLLEGE (Albany, New York)
ASSIGNEE(S) ALBANY MEDICAL COLLEGE (Albany, New York)
INVENTOR(S) Thomas T. Andersen (Albany, New York);  Herbert I. Jacobson (Albany, New York);  James A. Bennett (Delmar, New York);  Leroy Joseph (Brooklyn, New York);  Alberto Bryan (Philadelphia, Pennsylvania)
ABSTRACT The invention relates to compounds that are analogs of a cyclic peptide, cyclo[EKTOVNOGN], AFPep, that has anti-estrotrophic activity. The analogs of the invention include peptides and peptidomimetics that inhibit estrogen receptor-dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwanted estrogen induced cell proliferation, including breast cancer.
FILED Friday, January 29, 2016
APPL NO 15/010724
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 7/52 (20130101)
C07K 7/64 (20130101)
C07K 14/4715 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167464 Ringeisen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Bradley R. Ringeisen (Lorton, Virginia);  Russell Kirk Pirlo (Washington, District of Columbia);  Peter K. Wu (Ashland, Oregon)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Bradley R. Ringeisen (Lorton, Virginia);  Russell Kirk Pirlo (Washington, District of Columbia);  Peter K. Wu (Ashland, Oregon)
ABSTRACT Disclosed herein is a structure having: a porous polymeric film permeated by a first extracellular matrix material; and a topcoat layer comprising a second extracellular matrix gel disposed on the film. Also disclosed herein is a method of: providing a porous polymeric film; permeating the film with a first extracellular matrix material; and applying a topcoat layer of a second extracellular matrix material to the film. Also disclosed herein is a method of: laser-machining holes through a film comprising collagen to form a web-like structure.
FILED Tuesday, February 11, 2014
APPL NO 14/177240
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 7/63 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 11/02 (20130101) Original (OR) Class
C12N 11/08 (20130101)
C12N 2533/40 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49826 (20150115)
Y10T 428/24273 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167514 Newman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Aaron M. Newman (Palo Alto, California);  Arash Ash Alizadeh (San Mateo, California)
ABSTRACT Methods of deconvolving a feature profile of a physical system are provided herein. The present method may include: optimizing a regression between a) a feature profile of a first plurality of distinct components and b) a reference matrix of feature signatures for a second plurality of distinct components, wherein the feature profile is modeled as a linear combination of the reference matrix, and wherein the optimizing includes solving a set of regression coefficients of the regression, wherein the solution minimizes 1) a linear loss function and 2) an L2-norm penalty function; and estimating the fractional representation of one or more distinct components among the second plurality of distinct components present in the sample based on the set of regression coefficients. Systems and computer readable media for performing the subject methods are also provided.
FILED Friday, January 22, 2016
APPL NO 15/004611
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6809 (20130101)
C12Q 1/6809 (20130101)
C12Q 1/6881 (20130101)
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2537/165 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5005 (20130101)

Electric Digital Data Processing
G06F 19/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167540 Tuncer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Nihan Tuncer (Somerville, Massachusetts);  Christopher A. Schuh (Wayland, Massachusetts)
ABSTRACT There is provided herein a shape memory alloy wire that includes an alloy composition of CuAlMnNi and excluding grain refiner elements. The alloy composition includes 20 at %-28 at % Al, 2 at %-4 at % Ni, 3 at %-5 at % Mn with Cu as a remaining balance of the alloy composition. The alloy composition is disposed as an elongated wire of at least about 1 meter in length, having a wire diameter of less than about 150 microns. At least about 50 vol % of said alloy composition along said wire length has an oligocrystalline microstructure as-disposed in the wire and without thermal treatment of the wire.
FILED Wednesday, May 06, 2015
APPL NO 14/705247
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material
B21C 37/045 (20130101)

Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 11/005 (20130101)

Alloys
C22C 9/01 (20130101)

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/08 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 428/12 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167550 Wen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Aurora Flight Sciences Corporation (Manassas, Virginia)
ASSIGNEE(S) Aurora Flight Sciences Corporation (Manassas, Virginia)
INVENTOR(S) Ed Wen (Manassas, Virginia);  Dan Cottrell (Manassas, Virginia);  Adam Ehrmantraut (Manassas, Virginia);  Mark Blehar (Manassas, Virginia);  David Kordonowy (Manassas, Virginia)
ABSTRACT A multi-functional composite system generally comprises a core, a plurality of structural composite fiber layers, a matrix material, a connector configured to interface with one or more electrical devices and a composite conductor assembly, the composite conductor assembly having one or more conductors disposed between two or more insulating layers.
FILED Monday, June 01, 2015
APPL NO 14/726964
ART UNIT 2847 — Electrical Circuits and Systems
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 70/885 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/3076 (20130101)

Aeroplanes; Helicopters
B64C 3/20 (20130101)
B64C 3/26 (20130101)
B64C 3/185 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 45/00 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/06 (20130101) Original (OR) Class

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 7/0018 (20130101)
H01B 7/0823 (20130101)
H01B 7/0838 (20130101)
H01B 7/0861 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 2924/14 (20130101)
H01L 2924/01079 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/0393 (20130101)
H05K 3/281 (20130101)
H05K 3/321 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167722 Hough et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Matthew Andrew Hough (West Hartford, Connecticut);  Jeffrey S. Beattie (South Glastonbury, Connecticut)
ABSTRACT A turbine section comprises a rotor, blade and rim seal. The rotor comprises a rim defining an outer diameter surface, and a slot in the outer diameter surface. The blade comprises an airfoil, a platform surrounding the airfoil, a shank extending from the platform, a root extending from the shank for connecting to the slot, and a nub extending from the shank beneath the platform. The rim seal is disposed between the outer diameter surface and the nub. A method for cooling an outer diameter of a rotor disk comprises bleeding cooling air in a gas turbine engine, passing the flow of cooling air through a cover plate that retains a seal plate against the rotor disk, leaking the cooing air between a rotor disk rim and the seal plate, and guiding the cooling air across an outer diameter surface of the rotor disk rim utilizing a rim seal.
FILED Wednesday, September 10, 2014
APPL NO 15/021374
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/12 (20130101)
F01D 5/081 (20130101)
F01D 5/082 (20130101) Original (OR) Class
F01D 5/084 (20130101)
F01D 5/085 (20130101)
F01D 5/3007 (20130101)
F01D 5/3015 (20130101)
F01D 11/006 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2260/232 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167726 Devore et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S) United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Matthew A. Devore (Cromwell, Connecticut);  Matthew S. Gleiner (Norwalk, Connecticut);  Douglas C. Jenne (Ashford, Connecticut)
ABSTRACT A gas turbine engine component according to an exemplary aspect of the present disclosure includes, among other things, at least one cooling passage. The at least one cooling passage includes a first wall and a second wall bounding the at least one cooling passage, the first wall having a plurality of first surface features and the second wall having a plurality of second surface features. The plurality of first surface features and the plurality of second surface features are arranged such that a width of the cooling passage varies along a length of the cooling passage defined by the plurality of first surface features and the plurality of second surface features. The plurality of first surface features has a first profile, and the plurality of second surface features has a second, different profile. A casting core for forming cooling passages in an aircraft component is also disclosed.
FILED Monday, August 10, 2015
APPL NO 14/821831
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Foundry Moulding
B22C 9/10 (20130101)
B22C 9/106 (20130101)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/186 (20130101) Original (OR) Class
F01D 5/187 (20130101)
F01D 9/041 (20130101)
F01D 11/08 (20130101)
F01D 25/12 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2230/211 (20130101)
F05D 2240/12 (20130101)
F05D 2240/30 (20130101)
F05D 2240/55 (20130101)
F05D 2240/81 (20130101)
F05D 2240/126 (20130101)
F05D 2260/202 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/676 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168309 Motayed et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia);  GEORGE MASON UNIVERSITY (Fairfax, Virginia);  THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERICE (Washington, District of Columbia);  GEORGE MASON UNIVERSITY (Fairfax, Virginia);  THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia)
INVENTOR(S) Abhishek Motayed (Rockville, Maryland);  Geetha Aluri (Clifton Park, New York);  Albert V. Davydov (North Potomac, Maryland);  Mulpuri V. Rao (Fairfax Station, Virginia);  Vladimir P. Oleshko (Gaithersburg, Maryland);  Ritu Bajpai (Santa Clara, California);  Mona E. Zaghloul (Bethesda, Maryland)
ABSTRACT A nanostructure sensing device comprises a semiconductor nanostructure having an outer surface, and at least one of metal or metal-oxide nanoparticle clusters functionalizing the outer surface of the nanostructure and forming a photoconductive nanostructure/nanocluster hybrid sensor enabling light-assisted sensing of a target analyte.
FILED Thursday, February 08, 2018
APPL NO 15/891699
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/127 (20130101)
G01N 33/004 (20130101)
G01N 33/005 (20130101)
G01N 33/0031 (20130101)
G01N 33/0037 (20130101)
G01N 33/0042 (20130101)
G01N 33/0044 (20130101)
G01N 33/0047 (20130101)
G01N 33/0049 (20130101)
G01N 33/0054 (20130101)
G01N 33/0057 (20130101) Original (OR) Class

Technologies for Adaptation to Climate Change
Y02A 50/245 (20180101)
Y02A 50/246 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168338 Sabatini et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Congressionally Directed Medical Research Programs (CDMRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S) David M. Sabatini (Cambridge, Massachusetts);  Lynne Chantranupong (Cambridge, Massachusetts);  Rachel L. Wolfson (Cambridge, Massachusetts);  Jose Orozco (Boston, Massachusetts);  Robert A. Saxton (Cambridge, Massachusetts);  Shomit Sengupta (Belmont, Massachusetts)
ABSTRACT The present invention provides methods of identifying modulators of mTORC1 based upon their effect on GATOR2-Sestrin binding or Sestrin-leucine binding; and the use of such modulators to alter mTORC1 activity in a cell and to treat disease and conditions that are effected by mTORC1 activity.
FILED Friday, September 11, 2015
APPL NO 15/511007
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
G01N 33/5041 (20130101)
G01N 33/6872 (20130101) Original (OR) Class
G01N 2500/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168382 Hodges et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Eric Hodges (Simi Valley, California);  Ernest Coates (Ventura, California);  Angel Rosales-Ayala (Oxnard, California);  Masato Taniguchi (Camarillo, California);  Justin Cheung (Camarillo, California)
ABSTRACT Electronic test set embodiments and related methods are provided that can include a variety of safety components and/or processes which permit expandable or scalable automated testing of different types of equipment with or without installed sensitive, dangerous, vulnerable or expendable equipment. Embodiments can programmably or interface share measuring systems using expandable programmable interface systems that can scalably test a large number of components or electrical channels or bus lines. Embodiments can include multiple circuit board slot connectors adapted to receive programmable relay circuit cards that can selectively couple individual pins on ETS interface structures (e.g., cable connectors) to selected test equipment. Programmable relay circuit cards can be added to the ETS based on how many channels or bus connections are needed to interface with a system under test.
FILED Tuesday, August 09, 2016
APPL NO 15/232756
ART UNIT 2862 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/04 (20130101)
G01R 31/14 (20130101)
G01R 31/021 (20130101)
G01R 31/28 (20130101) Original (OR) Class
G01R 31/041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168392 Leary et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania);  SPANG, INC. (Pittsburgh, Pennsylvania);  U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Alex M. Leary (Pittsburgh, Pennsylvania);  Paul R. Ohodnicki (Pittsburgh, Pennsylvania);  Michael E. McHenry (Pittsburgh, Pennsylvania);  Vladimir Keylin (Pittsburgh, Pennsylvania);  Joseph Huth (Pittsburgh, Pennsylvania);  Samuel J. Kernion (Pittsburgh, Pennsylvania)
ABSTRACT A method includes producing an amorphous precursor to a nanocomposite, the amorphous precursor comprising a material that is substantially without crystals not exceeding 20% volume fraction; performing devitrification of the amorphous precursor, wherein the devitrification comprises a process of crystallization; forming, based on the devitrification, the nanocomposite with nano-crystals that contains an induced magnetic anisotropy; tuning, based on one or more of composition, temperature, configuration, and magnitude of stress applied during annealing and modification, the magnetic anisotropy of the nanocomposite; and adjusting, based on the tuned magnetic anisotropy, a magnetic permeability of the nanocomposite.
FILED Thursday, May 15, 2014
APPL NO 14/278836
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/02 (20130101) Original (OR) Class
G01R 33/0052 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/15333 (20130101)
H01F 41/0226 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168420 Fluhler et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Herbert U. Fluhler (Huntsville, Alabama);  Michael J. Guthrie (Huntsville, Alabama)
ASSIGNEE(S)
INVENTOR(S) Herbert U. Fluhler (Huntsville, Alabama);  Michael J. Guthrie (Huntsville, Alabama)
ABSTRACT A new radar is disclosed possessing desirable attributes for close range, short event time, high data rate sensing and data collection applications. A Continuous Wave (CW) or very high Pulse Repetition Frequency (PRF) Pulse based waveform, nominally with very high duty cycle (i.e. highly range aliased), is amplified and transmitted from one antenna, and after reflection from targets of interest, is received by one or a plurality of receive antennas. Both transmit and receive are optimally synchronous and phase coherent. The received signals are down converted to baseband leaving only the Doppler frequency from the targets of interest. These Doppler frequencies change over Fast Time as a function of the specific target trajectory and speed. A bank of time dependent correlation filters, each tuned to a different trajectory hypothesis, are used to integrate up the Doppler Signal for targets traveling the hypothesized trajectory, and decorrelated those that are not.
FILED Wednesday, July 15, 2015
APPL NO 14/800669
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 11/02 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/414 (20130101) Original (OR) Class
G01S 13/52 (20130101)
G01S 13/536 (20130101)
G01S 13/9023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168421 Bharatia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Pinkesh D. Bharatia (Cherry Hill, New Jersey);  Robert J. Santoro (Cherry Hill, New Jersey);  Nicholas R. Cifelli (Bloomington, Indiana);  Scott A. Storms (Woolwich Township, New Jersey);  Patrick J. Violante (Voorhees, New Jersey)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Pinkesh D. Bharatia (Cherry Hill, New Jersey);  Robert J. Santoro (Cherry Hill, New Jersey);  Nicholas R. Cifelli (Bloomington, Indiana);  Scott A. Storms (Woolwich Township, New Jersey);  Patrick J. Violante (Voorhees, New Jersey)
ABSTRACT Exemplary practice of the present invention provides a carriage including a body having a void, a vertical rod passing through the void, four legs arranged rectangularly and projecting obliquely downward and outward from the body, and a vertical coil spring coaxially encompassing a lower portion of the vertical rod. The carriage is coupled with a retroreflective laser target at the bottom of the vertical rod whereby the top of the spring pushes against the bottom of the body and the bottom of the spring pushes against the top of the target. The target continuously adjusts in height so that the bottom of the target remains in constant spring-tension contact with the surface on which the carriage sits or travels, supported by its legs. The carriage is electromechanically propelled, and laser tracking is conducted to direct laser beams at and receive laser retroreflections from the target at various surface locations. According to some inventive embodiments, one or more weights are implemented, in lieu of or in addition to a spring, to exert a downward force upon the target.
FILED Thursday, April 20, 2017
APPL NO 15/492926
ART UNIT 2878 — Optics
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 3/786 (20130101)
G01S 7/481 (20130101) Original (OR) Class
G01S 17/66 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/12 (20130101)
G02B 7/182 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168597 Frantz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jesse A. Frantz (Washington, District of Columbia);  Jason D. Myers (Alexandria, Virginia);  Christopher M. Spillmann (Annandale, Virginia);  Jawad Naciri (Arlington, Virginia);  Banahalli R. Ratna (Alexandria, Virginia);  Leslie Brandon Shaw (Woodbridge, Virginia);  Jasbinder S. Sanghera (Ashburn, Virginia);  Robel Y. Bekele (Washington, District of Columbia);  Jakub Kolacz (Alexandria, Virginia)
ABSTRACT A method for achieving alignment and optical switching of a liquid crystal (LC) layer that is deposited on chalcogenide glass (ChG). Direct brushing of ChG produces an effective LC alignment layer. Also disclosed is the related waveguide assembly for achieving alignment and optical switching of a liquid crystal (LC) layer deposited on chalcogenide glass (ChG).
FILED Tuesday, July 18, 2017
APPL NO 15/652604
ART UNIT 2871 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/313 (20130101) Original (OR) Class
G02F 1/1303 (20130101)
G02F 1/13378 (20130101)
G02F 1/133784 (20130101)
G02F 2201/12 (20130101)
G02F 2202/09 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10169251 Whelihan
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) David Whelihan (Framingham, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David Whelihan (Framingham, Massachusetts)
ABSTRACT A method for limiting execution of an encrypted computer program on a secure processor includes executing a first set of instructions encoding a test for determining whether a value of a register of the secure processor belongs to a set of valid register values encoded in the encrypted computer program. Execution of the first set of instructions causes the secure processor to read a first register value from the register of the secure processor, the register of the secure processor preventing repeated reads of a same value of the register, and determine whether the first register value belongs to the set of valid register values encoded in the encrypted computer program. Execution of further instructions of the encrypted computer program is prevented if the first register value does not belong to the set of valid register values encoded in the encrypted computer program.
FILED Monday, December 14, 2015
APPL NO 14/967856
ART UNIT 2438 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 12/1408 (20130101) Original (OR) Class
G06F 2212/1052 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/3234 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10169328 Beller et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charles E. Beller (Baltimore, Maryland);  Michael Drzewucki (Chantilly, Virginia);  Christopher Phipps (Arlington, Virginia);  Kristen M. Summers (Takoma Park, Maryland);  Julie T. Yu (Chantilly, Virginia)
ABSTRACT A mechanism is provided in a data processing system for identifying nonsense passages. The mechanism annotates an input passage with linguistic features to form an annotated passage. The mechanism counts a number of instances of each type of linguistic feature in the annotated passage to form a set of feature counts. The mechanism determines a value for a metric based on the set of feature counts and compares the value for the metric to a predetermined model threshold. The mechanism identifies whether the input passage is a nonsense passage based on a result of the comparison.
FILED Thursday, May 12, 2016
APPL NO 15/152747
ART UNIT 2176 — Graphical User Interface and Document Processing
CURRENT CPC
Electric Digital Data Processing
G06F 17/2715 (20130101)
G06F 17/2785 (20130101) Original (OR) Class
G06F 17/30734 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10169700 Alvarez-Icaza Rivera et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Rodrigo Alvarez-Icaza Rivera (San Jose, California);  John V. Arthur (Mountain View, California);  Andrew S. Cassidy (San Jose, California);  Paul A. Merolla (Palo Alto, California);  Dharmendra S. Modha (San Jose, California)
ABSTRACT Embodiments of the invention relate to a globally asynchronous and locally synchronous neuromorphic network. One embodiment comprises generating a synchronization signal that is distributed to a plurality of neural core circuits. In response to the synchronization signal, in at least one core circuit, incoming spike events maintained by said at least one core circuit are processed to generate an outgoing spike event. Spike events are asynchronously communicated between the core circuits via a routing fabric comprising multiple asynchronous routers.
FILED Tuesday, November 29, 2016
APPL NO 15/362948
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101) Original (OR) Class
G06N 3/049 (20130101)
G06N 3/063 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10169844 Andreopoulos et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Alexander Andreopoulos (San Jose, California);  Daniel F. Gruhl (San Jose, California);  Michael Karasick (White Plains, New York);  Dharmendra S. Modha (San Jose, California)
ABSTRACT One or more embodiments provide a neurosynaptic circuit that includes multiple neurosynaptic core circuits that: perform image distortion correction by converting a source image to a destination image by: taking as input a sequence of image frames of a video with one or more channels per frame, and converting dimensions and pixel distortion coefficients of each frame as one or more corresponding neuronal firing events. Each distorted pixel is mapped to zero or more undistorted pixels by processing each neuronal firing event corresponding to each pixel of each image frame. Corresponding pixel intensity values of each distorted pixel are processed to output undistorted pixels for each image frame as neuronal firing events for a spike representation of the destination image.
FILED Monday, April 30, 2018
APPL NO 15/967362
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/66 (20130101)
G06K 9/4604 (20130101)

Image Data Processing or Generation, in General
G06T 3/4046 (20130101) Original (OR) Class
G06T 5/006 (20130101)
G06T 2207/20084 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170392 Chainer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Timothy Joseph Chainer (Putnam Valley, New York);  Pritish Ranjan Parida (Fishkill, New York);  Mark Delorman Schultz (Ossining, New York)
ABSTRACT Techniques for wafer level integration of embedded cooling structures for integrated circuit devices are provided. In one embodiment, a method includes forming channel structures on a first surface of a silicon first wafer, wherein the channel structures respectively include radial channels that extend from central fluid distribution areas, and wherein integrated circuits are formed on a second surface of the silicon first wafer that opposes the first surface. The method can further include bonding a manifold wafer to the first surface of the silicon wafer such that inlet openings formed through the manifold wafer respectively connect to the central fluid distribution areas, thereby enclosing the radial channels and forming a bonded structure.
FILED Wednesday, April 05, 2017
APPL NO 15/479810
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/82 (20130101)
H01L 23/427 (20130101) Original (OR) Class
H01L 25/50 (20130101)
H01L 25/0655 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170611 Tang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Yan Tang (Oak Park, California);  Keisuke Shinohara (Thousand Oaks, California);  Dean C. Regan (Simi Valley, California);  Helen Hor Ka Fung (Agoura Hills, California);  Miroslav Micovic (Thousand Oaks, California)
ABSTRACT Semiconductor devices, such as transistors, FETs and HEMTs having a non-linear gate foot region and non-linear channel width are disclosed as well as methods of making and using such devices and the operational benefits of the devices.
FILED Friday, June 24, 2016
APPL NO 15/192942
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/0605 (20130101)
H01L 29/7786 (20130101) Original (OR) Class
H01L 29/42376 (20130101)
H01L 29/66431 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170656 Newman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Space Vehicles Directorate Contracting Division (AFRL/RVK)
APPLICANT(S) SolAero Technologies Corp. (Albuquerque, New Mexico)
ASSIGNEE(S) SolAero Technologies Corp. (Albuquerque, New Mexico)
INVENTOR(S) Fred Newman (Albuquerque, New Mexico);  Benjamin Cho (Albuquerque, New Mexico);  Mark A. Stan (Albuquerque, New Mexico);  Paul Sharps (Albuquerque, New Mexico)
ABSTRACT The present disclosure provides a multijunction solar cell that includes: a first sequence of layers of semiconductor material forming a first set of one or more solar subcells; a graded interlayer adjacent to said first sequence of layers; a second sequence of layers of semiconductor material forming a second set of one or more solar subcells; and a high band gap contact layer adjacent said second sequence of layers, wherein the high band gap contact layer is composed of p++ type InGaAlAs or InGaAs.
FILED Tuesday, February 17, 2015
APPL NO 14/623883
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0693 (20130101)
H01L 31/0725 (20130101)
H01L 31/0735 (20130101)
H01L 31/1844 (20130101)
H01L 31/1892 (20130101)
H01L 31/03046 (20130101)
H01L 31/03529 (20130101)
H01L 31/06875 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/544 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170729 Kim et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Woohong Kim (Lorton, Virginia);  Gary P. Kushto (Crofton, Maryland);  Zakya H. Kafafi (Alexandria, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Woohong Kim (Lorton, Virginia);  Gary P. Kushto (Crofton, Maryland);  Zakya H. Kafafi (Alexandria, Virginia)
ABSTRACT An electrically conductive film suited to use as a transparent anode, a method of forming the film, and an electronic device comprising the film are disclosed. The device includes a conductive polymer electrode defining first and second surfaces and having an electrical conductivity gradient between the first and second surfaces. A second electrode is spaced from the second surface by at least one organic material layer, such as a light emitting layer.
FILED Tuesday, May 06, 2014
APPL NO 14/270654
ART UNIT 2848 — Electrical Circuits and Systems
CURRENT CPC
Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/128 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/006 (20130101)
H01L 51/0021 (20130101)
H01L 51/0037 (20130101)
H01L 51/56 (20130101) Original (OR) Class
H01L 51/0094 (20130101)
H01L 51/5206 (20130101)
H01L 51/5215 (20130101)
H01L 2251/5346 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 33/28 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170817 Chang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Josephine B. Chang (Bedford Hills, New York);  John M. Cotte (New Fairfield, Connecticut)
ABSTRACT A technique relates to a superconducting airbridge on a structure. A first ground plane, resonator, and second ground plane are formed on a substrate. A first lift-off pattern is formed of a first lift-off resist and a first photoresist. The first photoresist is deposited on the first lift-off resist. A superconducting sacrificial layer is deposited while using the first lift-off pattern. The first lift-off pattern is removed. A cross-over lift-off pattern is formed of a second lift-off resist and a second photoresist. The second photoresist is deposited on the second lift-off resist. A cross-over superconducting material is deposited to be formed as the superconducting airbridge while using the cross-over lift-off pattern. The cross-over lift-off pattern is removed. The superconducting airbridge is formed to connect the first and second ground planes by removing the superconducting sacrificial layer underneath the cross-over superconducting material. The superconducting airbridge crosses over the resonator.
FILED Wednesday, June 24, 2015
APPL NO 14/749143
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 3/08 (20130101)
H01P 5/028 (20130101)
H01P 7/06 (20130101)
H01P 7/08 (20130101) Original (OR) Class
H01P 11/003 (20130101)
H01P 11/008 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/09 (20130101)
H05K 1/0237 (20130101)
H05K 3/00 (20130101)
H05K 3/4685 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49014 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170838 Garcia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Alberto V. Garcia (Hartsdale, New York);  Xiaoxiong Gu (White Plains, New York);  Duixian Liu (Scarsdale, New York)
ABSTRACT Package structures are provided having antenna-in-packages that are integrated with semiconductor RFIC (radio frequency integrated circuit) chips to form compact integrated radio/wireless communications systems that operate in the millimeter wave (mmWave) frequency range with radiation in broadside and end-fire directions.
FILED Friday, July 10, 2015
APPL NO 14/796062
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 19/077 (20130101)
G06K 19/07749 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 24/13 (20130101)
H01L 24/16 (20130101)
H01L 24/17 (20130101)
H01L 24/32 (20130101)
H01L 24/33 (20130101)
H01L 2224/131 (20130101)
H01L 2224/131 (20130101)
H01L 2224/16225 (20130101)
H01L 2224/16225 (20130101)
H01L 2224/16225 (20130101)
H01L 2224/16227 (20130101)
H01L 2224/17517 (20130101)
H01L 2224/32013 (20130101)
H01L 2224/32014 (20130101)
H01L 2224/32225 (20130101)
H01L 2224/32225 (20130101)
H01L 2224/33181 (20130101)
H01L 2224/73204 (20130101)
H01L 2224/73204 (20130101)
H01L 2224/73253 (20130101)
H01L 2924/00 (20130101)
H01L 2924/00012 (20130101)
H01L 2924/014 (20130101)
H01L 2924/15192 (20130101)
H01L 2924/15321 (20130101)
H01L 2924/15322 (20130101)

Antennas, i.e Radio Aerials
H01Q 1/38 (20130101)
H01Q 9/0407 (20130101) Original (OR) Class
H01Q 19/30 (20130101)
H01Q 21/28 (20130101)
H01Q 23/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170841 Tonn
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) David A Tonn (Charlestown, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) David A Tonn (Charlestown, Rhode Island)
ABSTRACT A dual mode antenna can be joined to an antenna feed. The antenna includes a slotted cylinder radiator that can be connected to the first conductor of the antenna feed and an electrically conductive ground plane that can be connected to the second conductor. The radiator axially extends perpendicularly from the ground plane and is electrically insulated therefrom. The first conductor can be joined to the radiator near one side of the slot. A reactive load is joined between the ground plane and the radiator near an opposite side of the slot. The reactive load impedes lower frequencies from the ground plane to the radiator. This allows the radiator to function as a monopole at lower frequencies and a slotted cylinder at higher frequencies.
FILED Thursday, January 05, 2017
APPL NO 15/398799
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/48 (20130101)
H01Q 13/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170888 Zheng et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Oracle International Corporation (Redwood Shores, California)
ASSIGNEE(S) Oracle International Corporation (Redwood Shore, California)
INVENTOR(S) Xuezhe Zheng (San Diego, California);  Ying Luo (San Diego, California);  Ashok V. Krishnamoorthy (San Diego, California);  Kannan Raj (San Diego, California)
ABSTRACT The disclosed embodiments provide a laser source comprising a silicon waveguide formed in a silicon layer, and a cascaded array of hybrid distributed feedback (DFB) lasers formed by locating sections of III-V gain material over the silicon waveguide. Each DFB laser in the cascaded array comprises a section of III-V gain material located over the silicon waveguide, wherein the section of III-V gain material includes an active region that generates light, and a Bragg grating located between the III-V gain material and the silicon waveguide. This Bragg grating has a resonance frequency within a gain bandwidth of the section of III-V material and is transparent to frequencies that differ from the resonance frequency. Moreover, each DFB laser has a hybrid mode that resides partially in the III-V gain material and partially in silicon.
FILED Thursday, November 03, 2016
APPL NO 15/343080
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/025 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/125 (20130101)
H01S 5/1228 (20130101) Original (OR) Class
H01S 5/4025 (20130101)

Transmission
H04B 10/506 (20130101)

Multiplex Communication
H04J 14/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10171031 Chakrabarti et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Anandaroop Chakrabarti (New York, New York);  Mark Ferriss (Tarrytown, New York);  Bodhisatwa Sadhu (White Plains, New York)
ABSTRACT An integrated electronic circuit is provided. The integrated electronic circuit includes a transconductance cell formed from transconductance cell devices. The integrated electronic circuit further includes active and passive decoupling circuits. The integrated electronic circuit also includes an oscillator having a tank that is direct current decoupled from the transconductance cell devices using the active and passive decoupling circuits to increase voltage swing and decrease phase noise of the oscillator.
FILED Monday, May 01, 2017
APPL NO 15/583458
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 1/04 (20130101) Original (OR) Class
H03B 5/1212 (20130101)
H03B 5/1215 (20130101)
H03B 5/1221 (20130101)
H03B 5/1228 (20130101)
H03B 5/1231 (20130101)
H03B 5/1265 (20130101)
H03B 2200/009 (20130101)

Pulse Technique
H03K 3/013 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10171050 Chakrabarti et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Anandaroop Chakrabarti (New York, New York);  Harish Krishnaswamy (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Anandaroop Chakrabarti (New York, New York);  Harish Krishnaswamy (New York, New York)
ABSTRACT In some embodiments, circuits for providing Class-E power amplifiers are provided, the circuits comprising: a first switch having a first side and a second side; a first Class-E load network coupled to the first side of the first switch; a second Class-E load network; and a second switch having a first side and a second side, the first side of the second switch being coupled the second side of the first switch and the second Class-E load network. In some embodiments, the circuits further comprise: a third switch having a first side and a second side; a third Class-E load network coupled to the first side of the third switch; a fourth Class-E load network; and a fourth switch having a first side and a second side, the first side of the fourth switch being coupled the second side of the third switch and the fourth Class-E load network.
FILED Monday, August 29, 2016
APPL NO 15/250447
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Amplifiers
H03F 1/56 (20130101)
H03F 3/2176 (20130101) Original (OR) Class
H03F 2200/222 (20130101)
H03F 2200/387 (20130101)
H03F 2200/402 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10171081 Bose et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Pradip Bose (Yorktown Heights, New York);  Alper Buyuktosunoglu (White Plains, New York);  Pierce I-Jen Chuang (Briarcliff Manor, New York);  Phillip John Restle (Katonah, New York);  Christos Vezyrtzis (New Rochelle, New York)
ABSTRACT Techniques facilitating on-chip supply noise voltage reduction and/or mitigation using local detection loops in a processor core are provided. In one example, a computer-implemented method can comprise detecting, by a processor core, a voltage droop at a first area of the processor core. The computer-implemented method can also comprise transmitting, by the processor core, voltage droop information to a local controller located in the first area and to a global controller located in the processor core. Further, the computer-implemented method can comprise applying, by the processor core, a first mitigation countermeasure at the first area of the processor core in response to a local instruction received from the local controller. The local instruction can comprise an indication of the first mitigation countermeasure.
FILED Friday, July 28, 2017
APPL NO 15/663033
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Pulse Technique
H03K 17/162 (20130101)
H03K 19/00361 (20130101) Original (OR) Class
H03K 19/00384 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10171084 Lu et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Wei Lu (Ann Arbor, Michigan);  Fuxi Cai (Ann Arbor, Michigan);  Patrick Sheridan (Ann Arbor, Michigan);  Chao Du (Ann Arbor, Michigan)
ABSTRACT Sparse representation of information performs powerful feature extraction on high-dimensional data and is of interest for applications in signal processing, machine vision, object recognition, and neurobiology. Sparse coding is a mechanism by which biological neural systems can efficiently process complex sensory data while consuming very little power. Sparse coding algorithms in a bio-inspired approach can be implemented in a crossbar array of memristors (resistive memory devices). This network enables efficient implementation of pattern matching and lateral neuron inhibition, allowing input data to be sparsely encoded using neuron activities and stored dictionary elements. The reconstructed input can be obtained by performing a backward pass through the same crossbar matrix using the neuron activity vector as input. Different dictionary sets can be trained and stored in the same system, depending on the nature of the input signals. Using the sparse coding algorithm, natural image processing is performed based on a learned dictionary.
FILED Tuesday, April 24, 2018
APPL NO 15/960772
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Static Stores
G11C 13/0069 (20130101)

Pulse Technique
H03K 19/17748 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 49/101 (20130101)

Selecting
H04Q 3/0004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10171589 Verma
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Dinesh C. Verma (New Castle, New York)
ABSTRACT Techniques for reducing interference in a network from management and control traffic to functional applications are provided. In one aspect, a method for regulating information flow between monitoring agents and a management server in a network includes the steps of: inserting an interface in the network to access stream based communications in the network; exporting control and data ports to each of the monitoring agents; receiving requests from one or more of the monitoring agents to establish sessions; and limiting a number of the sessions to open. A system for limiting interference in a network is also provided.
FILED Friday, October 23, 2015
APPL NO 14/921498
ART UNIT 2449 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/046 (20130101)
H04L 41/0896 (20130101)
H04L 43/10 (20130101)
H04L 67/141 (20130101) Original (OR) Class
H04L 69/329 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10172068 Mosko et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) CISCO TECHNOLOGY, INC. (San Jose, California)
ASSIGNEE(S) Cisco Technology, Inc. (San Jose, California)
INVENTOR(S) Marc E. Mosko (Santa Cruz, California);  Jose J. Garcia-Luna-Aceves (San Mateo, California)
ABSTRACT One embodiment provides a mobile ad-hoc network (MANET). The MANET includes a plurality of mobile nodes and a centralized controller node. The controller node includes a receiving mechanism configured to receive, from a source mobile node, a request for a service, with the request including an identifier associated with the requested service; an identification mechanism configured to identify a destination mobile node that provides the service associated with the identifier; a path-computation mechanism configured to compute a path between the source mobile node and the destination mobile node using a network graph for the mobile nodes; and a path-sending mechanism configured to send the computed path to at least the destination mobile node, which facilitates establishing a route between the source mobile node and the destination mobile node.
FILED Wednesday, January 22, 2014
APPL NO 14/161406
ART UNIT 2415 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/12 (20130101)
H04L 45/42 (20130101)
H04L 45/124 (20130101)

Wireless Communication Networks
H04W 40/04 (20130101) Original (OR) Class
H04W 40/24 (20130101)
H04W 40/32 (20130101)
H04W 84/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 10166503 Coleman et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Research Triangle Institute (Research Triangle Park, North Carolina)
ASSIGNEE(S) Research Triangle Institute (Research Triangle Park, North Carolina)
INVENTOR(S) Luke Coleman (Durham, North Carolina);  Marty Lail (Raleigh, North Carolina);  Kelly E. Amato (Cary, North Carolina);  Jak Tanthana (Durham, North Carolina)
ABSTRACT This invention is directed to methods and systems for controlling water in acid gas removal processes comprising the steps of a) treating the gas stream in an absorption zone with the NAS absorption liquid; b) direction the acid gas-loaded NAS absorption liquid to a regeneration zone; c) directing the regenerated NAS absorption liquid to step a); and d) controlling the first and second set of conditions.
FILED Friday, February 13, 2015
APPL NO 15/118722
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/1412 (20130101) Original (OR) Class
B01D 53/1425 (20130101)
B01D 53/1475 (20130101)
B01D 53/1493 (20130101)
B01D 2252/30 (20130101)
B01D 2252/40 (20130101)
B01D 2252/202 (20130101)
B01D 2252/204 (20130101)
B01D 2252/2026 (20130101)
B01D 2252/2028 (20130101)
B01D 2252/20405 (20130101)
B01D 2252/20421 (20130101)
B01D 2252/20426 (20130101)
B01D 2258/0233 (20130101)
B01D 2258/0283 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 10/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166751 Kramer et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Kevin J. Kramer (Pleasanton, California);  Andrew Bayramian (Manteca, California);  Bassem S. El-Dasher (Livermore, California);  Joseph C. Farmer (Tracy, California);  John C. Post (Livermore, California);  James A. Demuth (Mountain View, California)
ABSTRACT Systems and methods are disclosed for manufacturing a three dimensional (3D) part. In one implementation a system in accordance with the present disclosure may make use of an additive manufacturing (AM) subsystem for performing an AM operation to form the 3D part. The 3D part may be formed using a plurality of distinct material layers layered one on top of another. The system may also involve at least one of a laser peening (LP) subsystem and a High Velocity Laser Accelerated Deposition (HVLAD) subsystem. The LP subsystem may be used for laser peening a selected subquantity of the layers, to impart improved hardness to the selected subquantity of the layers and/or to the overall 3D part. The HVLAD subsystem may be used to bond at least one of the material layers to a previously laid down one of the material layers.
FILED Friday, June 13, 2014
APPL NO 14/303642
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/323 (20151001)
B23K 26/342 (20151001)
B23K 26/356 (20151001)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 9/007 (20130101)
B32B 15/08 (20130101)
B32B 15/043 (20130101)
B32B 2605/00 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201) Original (OR) Class
B33Y 99/00 (20141201)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/522 (20130101)
C04B 35/565 (20130101)
C04B 2235/6026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167209 Cho et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Young I. Cho (Cherry Hill, New Jersey);  Alexander Fridman (Philadelphia, Pennsylvania);  Daniel J. Cho (Wayne, Pennsylvania);  Alexander Rabinovich (Cherry Hill, New Jersey)
ASSIGNEE(S) DREXEL UNIVERISITY (Philadelphia, Pennsylvania)
INVENTOR(S) Young I. Cho (Cherry Hill, New Jersey);  Alexander Fridman (Philadelphia, Pennsylvania);  Daniel J. Cho (Wayne, Pennsylvania);  Alexander Rabinovich (Cherry Hill, New Jersey)
ABSTRACT A treatment system for treating water, such as produced water that is produced during hydraulic fracturing. The system employs a combination of a plasma spark discharge and an RF oscillating electric field. The plasma spark discharge and the RF oscillating electric field may be employed simultaneously or in an overlapping manner within a chamber to treat the water. The treatment system is able to kill microorganisms as well as reduce or eliminate fouling due to, for example, bicarbonates. In some embodiments, grids are employed to further enhance the heat produced by the RF oscillating electric field.
FILED Monday, November 30, 2015
APPL NO 14/954495
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/487 (20130101) Original (OR) Class
C02F 1/4608 (20130101)
C02F 2303/04 (20130101)
C02F 2305/023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167430 Hart et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Todd R. Hart (Kennewick, Washington);  Douglas C. Elliott (Richland, Washington);  Andrew J. Schmidt (Richland, Washington);  Richard T. Hallen (Richland, Washington)
ABSTRACT Embodiments of a method for producing bio-oil include hydrothermal liquefaction of a biomass (e.g., a lignocellulosic biomass) feedstock to provide a process stream comprising crude oil and an aqueous fraction. The process stream is catalytically upgraded by contact with a sulfided-ruthenium catalyst, in the absence of added hydrogen, at a temperature and pressure effective to reduce an oxygen content of the crude oil, reduce a nitrogen content of the crude oil, reduce a total acid number of the crude oil, increase a H:C mole ratio of the crude oil, reduce a density of the crude oil, reduce a moisture content of the crude oil, reduce viscosity of the crude oil, or any combination thereof, thereby producing an upgraded oil and an upgraded aqueous fraction, which are subsequently separated. The catalytic upgrading process may be a plug-flow process and/or may be performed at or near liquefaction conditions.
FILED Tuesday, June 28, 2016
APPL NO 15/195553
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 1/06 (20130101)
C10G 3/47 (20130101) Original (OR) Class
C10G 3/50 (20130101)
C10G 2300/202 (20130101)
C10G 2300/1014 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167460 Foukaraki et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) DANISCO US INC (Palo Alto, California)
ASSIGNEE(S) DANISCO US INC (, California)
INVENTOR(S) Maria Foukaraki (Rotterdam, Netherlands);  Ronaldus Wilhelmus Hommes (Haarlem, Netherlands);  Thijs Kaper (Half Moon Bay, California);  Bradley R. Kelemen (Menlo Park, California);  Slavko Kralj (Oegstgeest, Netherlands);  Suzanne E. Lantz (San Carlos, California);  Igor Nikolaev (Noordwijk, Netherlands);  Wilhelmus Van Der Kley (The Hague, Netherlands);  Johan Franciscus Thomas Van Lieshout (Utrecht, Netherlands);  Sander Van Stigt Thans (Zevenbergen, Netherlands)
ABSTRACT Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.
FILED Thursday, July 24, 2014
APPL NO 14/909031
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0083 (20130101)
C12N 9/2434 (20130101)
C12N 9/2437 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/02 (20130101)
C12P 19/14 (20130101)

Enzymes
C12Y 302/01004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167461 Schnorr et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Novozymes, Inc. (Davis, California);  Novoyzmes A/S (Bagsvaerd, Denmark)
ASSIGNEE(S) Novozymes, Inc. (Davis, California);  Novozymes A/S (Bagsvaerd, Denmark)
INVENTOR(S) Kirk Schnorr (Holt, Denmark);  Randall Kramer (Lincoln, California)
ABSTRACT The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
FILED Monday, February 22, 2016
APPL NO 15/049860
ART UNIT 1663 — Plants
CURRENT CPC
Peptides
C07K 14/38 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2434 (20130101)
C12N 9/2437 (20130101) Original (OR) Class
C12N 15/62 (20130101)
C12N 15/8246 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/02 (20130101)
C12P 19/12 (20130101)
C12P 19/14 (20130101)

Enzymes
C12Y 302/01004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167488 Keasling et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jay D. Keasling (Berkeley, California);  Christopher B. Eiben (Berkeley, California)
ABSTRACT Cells comprising a heterologous metabolic pathway are configured to produce a terpene product containing non-multiples of five carbon, particularly wherein the pathway comprises heterologous Lepidoptera insect juvenile hormone biosynthetic pathway enzymes of the insect's mevalonate pathway.
FILED Friday, November 03, 2017
APPL NO 15/803735
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0006 (20130101)
C12N 9/88 (20130101)
C12N 9/90 (20130101)
C12N 9/1025 (20130101)
C12N 9/1029 (20130101)
C12N 9/1085 (20130101)
C12N 9/1205 (20130101)
C12N 15/52 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 5/007 (20130101) Original (OR) Class
C12P 9/00 (20130101)

Enzymes
C12Y 101/01034 (20130101)
C12Y 203/0301 (20130101)
C12Y 203/01009 (20130101)
C12Y 205/01001 (20130101)
C12Y 207/01036 (20130101)
C12Y 402/03027 (20130101)
C12Y 503/03002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167523 Tuskan et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Gerald A. Tuskan (Oak Ridge, Tennessee);  Udaya C. Kalluri (Knoxville, Tennessee)
ABSTRACT The invention provides plants having improved biomass properties of increased biomass quantity and density, increased cellulose content and deceased lignin content and improved sugar release efficiency, methods of generating (genetically modifying) and/or selecting (natural variant collections) plants with such preferred attributes of cellulose, lignin and sugar release, and uses of such plants. The inventors have determined that the expression of the gene, Potri.001G375700 (belonging to IQD signaling protein family containing a canonical calmodulin-binding domain) and/or activity of Potri.001G375700, modulates cellulose, lignin synthesis, sugar release and growth in plants.
FILED Wednesday, May 04, 2016
APPL NO 15/145996
ART UNIT 1663 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8218 (20130101)
C12N 15/8261 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6895 (20130101) Original (OR) Class
C12Q 2600/13 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Technologies for Adaptation to Climate Change
Y02A 40/146 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167925 Sanders et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Amber Kinetics, Inc. (Fremont, California)
ASSIGNEE(S) Amber Kinetics, Inc. (Fremont, California)
INVENTOR(S) Seth Sanders (Berkeley, California);  Eric Sun (Union City, California);  Mike He (San Jose, California);  Matthew Senesky (Berkeley, California);  Edward Young Chiao (San Jose, California)
ABSTRACT An energy storage system including a solid steel flywheel rotor, journals, and separate stub shafts for connecting to the journals has improved material properties offers improved energy storage at reduced cost.
FILED Tuesday, July 28, 2015
APPL NO 14/811012
ART UNIT 3656 — Material and Article Handling
CURRENT CPC
Springs; Shock-absorbers; Means for Damping Vibration
F16F 15/30 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168087 Munk et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Jeffrey D. Munk (Knoxville, Tennessee);  Moonis R. Ally (Oak Ridge, Tennessee)
ABSTRACT A heat pump including an integrated system for the management of refrigerant charge is provided. The heat pump includes an indoor line and an outdoor line that are connected to a compressor through a reversing valve. Refrigerant charge is managed by coupling the inactive line to the suction side of the compressor. For example, the heat pump can include an expansion valve to couple the inactive line to the compressor to supplement the flow-rate of refrigerant. The heat pump is operable in a dedicated water heating mode and a space cooling and water heating mode in some embodiments, while other modes of operation are contemplated in other embodiments.
FILED Thursday, September 03, 2015
APPL NO 14/844757
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 5/02 (20130101)
F25B 13/00 (20130101)
F25B 41/003 (20130101)
F25B 41/04 (20130101)
F25B 45/00 (20130101) Original (OR) Class
F25B 2313/021 (20130101)
F25B 2313/02741 (20130101)
F25B 2339/047 (20130101)
F25B 2400/19 (20130101)
F25B 2400/0409 (20130101)
F25B 2400/0411 (20130101)
F25B 2600/05 (20130101)
F25B 2600/2501 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168108 Schultz
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Mark D. Schultz (Ossining, New York)
ABSTRACT Methods of using heat sinks include placing a pin fin compliant heat sink on a non-flat surface. The pin fin complaint heat sink has top and bottom plates connected by a plurality of pins arranged vertically between the top and bottom plates. The top and bottom plates are vertically conformed to local deviations of the non-flat surface. The top and bottom plates are laterally conformed to an overall shape of the surface. At least either the top or bottom plate is corrugated.
FILED Thursday, January 25, 2018
APPL NO 15/879913
ART UNIT 3744 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 15/26 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 3/022 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168245 McCallen et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE CSU, CHICO RESEARCH FOUNDATION (Chico, California);  Jason Coates (Chico, California);  Nick Repanich (Chico, California);  William Harvey Wattenburg (Chico, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) David B. McCallen (Livermore, California);  Jason Coates (Chico, California);  Nick Repanich (Chico, California);  William Harvey Wattenburg (Chico, California)
ABSTRACT A sensor system provides measurement of building interstory drift based on a laser beam impinging on a discrete diode sensor array. The diode sensor array determines the location at which a projected laser bean strikes the array, which provides a direct measurement of interstory drift. The diode sensor array is a two dimensional array of discrete diodes that allow the location of an impinging laser beam to be very accurately tracked as the beam moves back-and-forth across the diode array. Local rotations of the laser source that result from rotations of structural members (e.g. floor beam rotation) are appropriately corrected for. This allows accurate, dynamic measurements of the interstory drift between two floor levels of a shaking building.
FILED Wednesday, April 27, 2016
APPL NO 15/509757
ART UNIT 2877 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/16 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 5/0025 (20130101)
G01M 5/0041 (20130101) Original (OR) Class
G01M 7/02 (20130101)
G01M 7/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168275 Orcutt
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Jason S. Orcutt (Katonah, New York)
ABSTRACT Methods and systems for detecting a gas or liquid in an environment include measuring a reference signal at each of a set of wavelengths by passing a signal at each wavelength through a reference cell having a gas or liquid to be detected. A sensing signal is measured at each of the plurality of wavelengths by coupling each wavelength to a ring resonator in the environment. A set of wavelengths that correspond to an absorption curve of the gas or liquid to be detected is determined. A concentration of the gas or liquid to be detected in the environment is determined based on amplitudes of the sensing signal at each of the set of wavelengths.
FILED Tuesday, May 23, 2017
APPL NO 15/603084
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/27 (20130101)
G01N 21/31 (20130101)
G01N 21/255 (20130101) Original (OR) Class
G01N 33/0022 (20130101)
G01N 33/0047 (20130101)
G01N 2201/0873 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/29338 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168334 Mor et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Gil G. Mor (Cheshire, Connecticut);  David C. Ward (Las Vegas, Nevada);  Patricia Bray-Ward (Las Vegas, Nevada)
ABSTRACT The claimed invention describes methods to diagnose or aid in the diagnosis of cancer. The claimed methods are based on the identification of biomarkers which are particularly well suited to discriminate between cancer subjects and healthy subjects. These biomarkers were identified using a unique and novel screening method described herein. The biomarkers identified herein can also be used in the prognosis and monitoring of cancer. The invention comprises the use of leptin, prolactin, OPN and IGF-II for diagnosing, prognosis and monitoring of ovarian cancer.
FILED Friday, September 16, 2016
APPL NO 15/268134
ART UNIT 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/112 (20130101)
C12Q 2600/136 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57415 (20130101)
G01N 33/57419 (20130101)
G01N 33/57449 (20130101)
G01N 33/57484 (20130101) Original (OR) Class
G01N 2333/65 (20130101)
G01N 2333/99 (20130101)
G01N 2333/575 (20130101)
G01N 2333/4703 (20130101)
G01N 2333/5756 (20130101)
G01N 2500/04 (20130101)
G01N 2800/52 (20130101)

Electric Digital Data Processing
G06F 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168358 Sappok et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Filter Sensing Technologies, Inc. (Malden, Massachusetts)
ASSIGNEE(S) CTS CORPORATION (Lisle, Illinois)
INVENTOR(S) Alexander Sappok (Cambridge, Massachusetts);  Roland Smith, III (Medford, Massachusetts);  Leslie Bromberg (Sharon, Massachusetts)
ABSTRACT A radio-frequency probe system with a transmitting or receiving element integrated into a cable assembly is disclosed. In some embodiments a preferred configuration may contain one or more sensing elements integrated into the transmitting or receiving element. In another embodiment, the radio frequency probe comprises an antenna body fixed to a coaxial cable, in which the center conductor of the coaxial cable serves as the transmitting or receiving element. A method for monitoring, transmitting, or detecting one or more parameters using a single radio frequency probe is also disclosed.
FILED Friday, November 07, 2014
APPL NO 14/535398
ART UNIT 2868 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 22/00 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 1/06772 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168392 Leary et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania);  SPANG, INC. (Pittsburgh, Pennsylvania);  U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Alex M. Leary (Pittsburgh, Pennsylvania);  Paul R. Ohodnicki (Pittsburgh, Pennsylvania);  Michael E. McHenry (Pittsburgh, Pennsylvania);  Vladimir Keylin (Pittsburgh, Pennsylvania);  Joseph Huth (Pittsburgh, Pennsylvania);  Samuel J. Kernion (Pittsburgh, Pennsylvania)
ABSTRACT A method includes producing an amorphous precursor to a nanocomposite, the amorphous precursor comprising a material that is substantially without crystals not exceeding 20% volume fraction; performing devitrification of the amorphous precursor, wherein the devitrification comprises a process of crystallization; forming, based on the devitrification, the nanocomposite with nano-crystals that contains an induced magnetic anisotropy; tuning, based on one or more of composition, temperature, configuration, and magnitude of stress applied during annealing and modification, the magnetic anisotropy of the nanocomposite; and adjusting, based on the tuned magnetic anisotropy, a magnetic permeability of the nanocomposite.
FILED Thursday, May 15, 2014
APPL NO 14/278836
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/02 (20130101) Original (OR) Class
G01R 33/0052 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/15333 (20130101)
H01F 41/0226 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168674 Buerger et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Stephen Buerger (Albuquerque, New Mexico);  Joshua Alan Love (Albuquerque, New Mexico);  Jason C. Neely (Albuquerque, New Mexico);  Wendy A. Amai (Albuquerque, New Mexico);  Charles Q. Little (Peralta, New Mexico)
ABSTRACT A control architecture and associated control methods are under development to allow a single user to control a team of multiple heterogeneous UMS as they conduct multi-faceted (i.e. multi-objective) missions in real time is disclosed. The control architecture is hierarchical, modular and layered and enables operator interaction at each layer, ensuring the human operator is in close control of the unmanned team at all times. The architecture and key data structures are introduced. Two approaches to distributed collaborative control of heterogeneous unmanned systems are described, including an extension of homogeneous swarm control and a novel application of distributed model predictive control. Initial results are presented, demonstrating heterogeneous UMS teams conducting collaborative missions.
FILED Tuesday, April 22, 2014
APPL NO 14/258986
ART UNIT 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 15/02 (20130101) Original (OR) Class

Systems for Controlling or Regulating Non-electric Variables
G05D 1/027 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/47 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10169445 Weinstein et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
Office of Science (DOE-SC)
SLAC National Accelerator Laboratory (SLAC)
Federally Funded Research and Development Center (FFRDC)
Operated by Stanford University (LSJU) at Menlo Park, CA
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California);  Ramot at Tel Aviv University Ltd. (Tel Aviv, Israel)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California);  Ramot at Tel Aviv University Ltd. (Tel Aviv, Israel)
INVENTOR(S) Marvin Weinstein (Palo Alto, California);  David Horn (Tel Aviv, Israel)
ABSTRACT In the present work, quantum clustering is extended to provide a dynamical approach for data clustering using a time-dependent Schrödinger equation. To expedite computations, we can approximate the time-dependent Hamiltonian formalism by a truncated calculation within a set of Gaussian wave-functions (coherent states) centered around the original points. This allows for analytic evaluation of the time evolution of all such states, opening up the possibility of exploration of relationships among data points through observation of varying dynamical-distances among points and convergence of points into clusters. This formalism may be further supplemented by preprocessing, such as dimensional reduction through singular value decomposition and/or feature filtering. Additionally, the parameters of the analysis can be modified in order to improve the efficiency of the dynamic quantum clustering processes.
FILED Monday, September 22, 2014
APPL NO 14/492677
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/30601 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/622 (20130101)
G06K 9/6247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170274 Stevens et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Andrew J. Stevens (Richland, Washington);  Libor Kovarik (West Richland, Washington);  Nigel D. Browning (Richland, Washington)
ABSTRACT Transmission microscopy imaging systems include a mask and/or other modulator situated to encode image beams, e.g., by deflecting the image beam with respect to the mask and/or sensor. The beam is modulated/masked either before or after transmission through a sample to induce a spatially and/or temporally encoded signal by modifying any of the beam/image components including the phase/coherence, intensity, or position of the beam at the sensor. For example, a mask can be placed/translated through the beam so that several masked beams are received by a sensor during a single sensor integration time. Images associated with multiple mask displacements are then used to reconstruct a video sequence using a compressive sensing method. Another example of masked modulation involves a mechanism for phase-retrieval, whereby the beam is modulated by a set of different masks in the image plane and each masked image is recorded in the diffraction plane.
FILED Wednesday, October 05, 2016
APPL NO 15/286502
ART UNIT 2881 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/00 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/20 (20130101)
G03F 7/30 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 37/09 (20130101)
H01J 37/20 (20130101)
H01J 37/26 (20130101)
H01J 37/28 (20130101)
H01J 37/222 (20130101) Original (OR) Class
H01J 37/244 (20130101)
H01J 2237/226 (20130101)
H01J 2237/0453 (20130101)
H01J 2237/2802 (20130101)
H01J 2237/24455 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170650 Curran et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Seamus Curran (Houston, Texas);  Sampath Dias (Houston, Texas);  Kang-Shyang Liao (Houston, Texas);  Soniya Devi Yambem (Houston, Texas);  Amrita Haldar (Houston, Texas);  Nigel Alley (Houston, Texas)
ASSIGNEE(S) UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S) Seamus Curran (Houston, Texas);  Sampath Dias (Houston, Texas);  Kang-Shyang Liao (Houston, Texas);  Soniya Devi Yambem (Houston, Texas);  Amrita Haldar (Houston, Texas);  Nigel Alley (Houston, Texas)
ABSTRACT According to some embodiments, the present invention provides a novel photovoltaic solar cell system from photovoltaic modules that are vertically arrayed in a stack format using thin film semiconductors selected from among organic and inorganic thin film semiconductors. The stack cells may be cells that are produced in a planar manner, then vertically oriented in an angular form, also termed herein tilted, to maximize the light capturing aspects. The use of a stack configuration system as described herein allows for the use of a variety of electrode materials, such as transparent materials or semitransparent metals. Light concentration can be achieved by using fresnel lens, parabolic mirrors or derivatives of such structures. The light capturing can be controlled by being reflected back and forth in the photovoltaic system until significant quantities of the resonant light is absorbed. Light that passes to the very end and can be reflected back through the device by beveling or capping the end of the device with a different refractive index material, or alternatively using a reflective surface. The contacting between stacked cells can be done in series or parallel. According to some embodiments, the present invention uses a concentrator architecture where the light is channeled into the cells that contain thermal fluid channels (using a transparent fluid such as water) to absorb and hence reduce the thermal energy generation.
FILED Tuesday, December 21, 2010
APPL NO 12/975038
ART UNIT 1757 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/302 (20130101)
H01L 31/043 (20141201)
H01L 31/055 (20130101)
H01L 31/0322 (20130101) Original (OR) Class
H01L 31/0521 (20130101)
H01L 31/0543 (20141201)
H01L 31/0749 (20130101)
H01L 51/426 (20130101)
H01L 51/4253 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/52 (20130101)
Y02E 10/541 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170652 King et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Richard R. King (Thousand Oaks, California);  Christopher M. Fetzer (Valencia, California);  Dimitri D. Krut (Encino, California);  Nasser H. Karam (La Canada, California)
ASSIGNEE(S) THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S) Richard R. King (Thousand Oaks, California);  Christopher M. Fetzer (Valencia, California);  Dimitri D. Krut (Encino, California);  Nasser H. Karam (La Canada, California)
ABSTRACT A semiconductor device structure having increased photogenerated current density, and increased current output is disclosed. The device includes low bandgap absorber regions that increase the range of wavelengths at which photogeneration of charge carriers takes place, and for which useful current can be collected. The low bandgap absorber regions may be strain balanced by strain-compensation regions, and the low bandgap absorber regions and strain-compensation regions may be formed from the same ternary semiconductor family. The device may be a solar cell, subcell, or other optoelectronic device with a metamorphic or lattice-mismatched base layer, for which the low bandgap absorber region improves the effective bandgap combination of subcells and current balance within the multijunction cell, for higher efficiency conversion of the solar spectrum.
FILED Tuesday, March 22, 2011
APPL NO 13/069274
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0687 (20130101)
H01L 31/0725 (20130101)
H01L 31/035236 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/544 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170750 Liang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Chengdu Liang (Knoxville, Tennessee);  Nancy J. Dudney (Knoxville, Tennessee);  Zhan Lin (Albany, California);  Zengcai Liu (Savoy, Illinois)
ABSTRACT A lithium sulfur cell has a cathode including Li3PS4+n (0<n<9), an electrolyte, and an anode comprising lithium. A cathode for a lithium sulfur cell is also disclosed.
FILED Tuesday, September 13, 2016
APPL NO 15/264321
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/136 (20130101)
H01M 4/0407 (20130101)
H01M 4/622 (20130101)
H01M 4/625 (20130101)
H01M 4/1397 (20130101) Original (OR) Class
H01M 4/5815 (20130101)
H01M 10/058 (20130101)
H01M 10/0525 (20130101)
H01M 10/0562 (20130101)
H01M 2004/028 (20130101)
H01M 2220/20 (20130101)
H01M 2300/0068 (20130101)
H01M 2300/0071 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/122 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/54 (20151101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/7011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170756 Lu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Jun Lu (Bolingbrook, Illinois);  Rui Xu (Westmont, Illinois);  Khalil Amine (Oakbrook, Illinois);  Xiulei Ji (Corvallis, Oregon)
ABSTRACT An electrochemical device includes a cathode containing graphene-wrapped Li2S nanoparticles. The graphene-wrapped Li2S nanoparticles are prepared by a method including heating lithium metal, and a carbon-sulfur source or a carbon source and a sulfur source in a sealed container at a temperature to produce lithium vapors, and vapors of the carbon-sulfur source or vapors of the carbon source and vapors of the sulfur source; and cooling the sealed container to produce the graphene-wrapped Li2S nanoparticles.
FILED Wednesday, December 16, 2015
APPL NO 14/971676
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/366 (20130101) Original (OR) Class
H01M 4/0471 (20130101)
H01M 4/587 (20130101)
H01M 4/625 (20130101)
H01M 4/5815 (20130101)
H01M 10/052 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/735 (20130101)
Y10S 977/842 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170759 Seo et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Dong-Kyun Seo (Chandler, Arizona);  Daniel Mieritz (Tempe, Arizona);  Candace Chan (Phoenix, Arizona);  Ran Zhao (Mesa, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Dong-Kyun Seo (Chandler, Arizona);  Daniel Mieritz (Tempe, Arizona);  Candace Chan (Phoenix, Arizona);  Ran Zhao (Mesa, Arizona)
ABSTRACT Forming a metal oxide by treating an acidic solution containing a metal to yield a precursor in the form of a semi-liquid, semi-solid or solid, and treating the precursor to yield a product including the metal oxide. An organic or inorganic component may be combined with the precursor to yield a second semi-liquid, semi-solid or solid. The product may be treated to yield a new material. In some cases, the metal oxide has an empirical formula HxM2A1y-A2z, where M represents a transition metal or any combination of transition metals in Groups 3-12; A1 is a first oxyanion; A2 is a second oxyanion; 0≤x≤3; 0≤y≤3; 0≤z≤3; and y+z>0.
FILED Thursday, June 12, 2014
APPL NO 14/899953
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 25/45 (20130101)
C01B 25/372 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 23/053 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101)
H01M 4/136 (20130101)
H01M 4/485 (20130101) Original (OR) Class
H01M 10/05 (20130101)
H01M 10/052 (20130101)
H01M 10/054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170765 Liu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Gao Liu (Piedmont, California);  Vincent S. Battaglia (San Anselmo, California);  Sang-Jae Park (Walnut Creek, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Gao Liu (Piedmont, California);  Vincent S. Battaglia (San Anselmo, California);  Sang-Jae Park (Walnut Creek, California)
ABSTRACT A family of carboxylic acid groups containing fluorene/fluorenon copolymers is disclosed as binders of silicon particles in the fabrication of negative electrodes for use with lithium ion batteries. Triethyleneoxide side chains provide improved adhesion to materials such as, graphite, silicon, silicon alloy, tin, tin alloy. These binders enable the use of silicon as an electrode material as they significantly improve the cycle-ability of silicon by preventing electrode degradation over time. In particular, these polymers, which become conductive on first charge, bind to the silicon particles of the electrode, are flexible so as to better accommodate the expansion and contraction of the electrode during charge/discharge, and being conductive promote the flow battery current.
FILED Thursday, September 24, 2015
APPL NO 14/863486
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 212/32 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/02 (20130101)
C08G 2261/312 (20130101)
C08G 2261/411 (20130101)
C08G 2261/516 (20130101)
C08G 2261/1412 (20130101)
C08G 2261/3142 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/005 (20130101)
C08J 2365/00 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/08 (20130101)
C08K 3/08 (20130101)

Compositions of Macromolecular Compounds
C08L 65/00 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/24 (20130101)
C09D 133/10 (20130101)
C09D 133/14 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/12 (20130101)
H01B 1/22 (20130101)
H01B 1/24 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/134 (20130101)
H01M 4/364 (20130101)
H01M 4/386 (20130101)
H01M 4/387 (20130101)
H01M 4/0402 (20130101)
H01M 4/587 (20130101)
H01M 4/622 (20130101)
H01M 4/623 (20130101) Original (OR) Class
H01M 4/624 (20130101)
H01M 4/1395 (20130101)
H01M 10/0525 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/122 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170795 Zhang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Ji-Guang Zhang (Richland, Washington);  Ruiguo Cao (Richland, Washington);  Wesley A. Henderson (Richland, Washington);  Kuber Mishra (Columbia, South Carolina);  Wu Xu (Richland, Washington)
ABSTRACT Embodiments of a non-aqueous electrolyte for a rechargeable sodium (Na)-based battery comprise a sodium salt and a nonaqueous solvent, the electrolyte having a sodium salt concentration ≥2.5 M or a solvent-sodium salt mole ratio ≤4:1. Na-based rechargeable batteries including the electrolyte exhibit both high cycling stability and high coulombic efficiency (CE). Some embodiments of the disclosed batteries attain a CE≥80% within 10-30 charge-discharge cycles and maintain a CE≥80% for at least 100 charge-discharge cycles. In certain embodiments, the battery is an anode-free battery in the as-assembled initial state.
FILED Tuesday, September 29, 2015
APPL NO 14/869647
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/381 (20130101)
H01M 4/661 (20130101)
H01M 4/663 (20130101)
H01M 4/5815 (20130101)
H01M 10/054 (20130101)
H01M 10/0568 (20130101) Original (OR) Class
H01M 10/0569 (20130101)
H01M 2300/0025 (20130101)
H01M 2300/0028 (20130101)
H01M 2300/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170799 Ouchi et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Takanari Ouchi (Brookline, Massachusetts);  Hojong Kim (State College, Pennsylvania);  Donald R. Sadoway (Cambridge, Massachusetts)
ABSTRACT An electrochemical cell includes a negative electrode having at least two active metals, a positive electrode having a metal or alloy, and an electrolyte having a cation of each of the active metals. The electrolyte defines first and second interfaces with the positive electrode being in contact with the first interface and the negative electrode being in contact with the second interface. The electrolyte is configured to allow the cations of the active metals to be transferred from the negative electrode to the positive electrode during discharging and to be transferred from the positive electrode to the negative electrode during charging. The electrolyte exists as a liquid phase and the negative electrode and the positive electrode exist as liquid or partially liquid phases at operating temperatures of the electrochemical cell.
FILED Monday, December 14, 2015
APPL NO 14/968381
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/399 (20130101) Original (OR) Class
H01M 2220/10 (20130101)
H01M 2300/0048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10171189 Musgrove et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Cameron H. Musgrove (Tulsa, Oklahoma);  Douglas Thompson (Albuquerque, New Mexico)
ABSTRACT Various technologies for isolating a signal of interest from signals received contemporaneously by an antenna are described herein. A time period for which a signal of interest is present in a second signal can be identified based upon ratios of values of the second signal to the mean value of the second signal. When the ratio of the value of the second signal at a particular time to the mean of the second signal exceeds a threshold value, the signal of interest is considered to be present in the second signal.
FILED Thursday, January 04, 2018
APPL NO 15/862316
ART UNIT 2656 — Digital Audio Data Processing
CURRENT CPC
Transmission
H04B 15/02 (20130101)
H04B 17/23 (20150115)
H04B 17/345 (20150115) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10172226 Nebel et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Tibbar Plasma Technologies, Inc. (Los Alamos, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Richard Nebel (Los Alamos, New Mexico);  Cihan Akcay (Los Alamos, New Mexico);  Daniel Barnes (Lamy, New Mexico);  Juan Fernandez (Los Alamos, New Mexico);  John Finn (Los Alamos, New Mexico);  William Gibson (Los Alamos, New Mexico);  Aaron McEvoy (Los Alamos, New Mexico);  Keith Moser (Libertyville, Illinois);  Liviu Popa-Simil (Los Alamos, New Mexico)
ABSTRACT An apparatus and corresponding systems and methods for managing electric power, particularly a transformer system and method, and more specifically a transformer for transforming direct current to alternating current. An example apparatus includes a chamber configured to contain plasma. The apparatus includes input electrodes disposed at least partially within the chamber, and configured to receive direct current input into the chamber. The input electrodes are configured to cause the input direct current to induce motion in the plasma. Motion induced in the plasma transforms current flowing there-through. Output electrodes extend from the chamber, which output electrodes may rotated in a controlled manner. The output electrodes conduct a three or one phase alternating current, from the induced motion in the plasma, for delivery from the chamber.
FILED Friday, October 28, 2016
APPL NO 15/338197
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 7/42 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/16 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 10166080 Balicki et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Marcin Arkadiusz Balicki (Baltimore, Maryland);  Kevin C. Olds (Baltimore, Maryland);  Russell H. Taylor (Severna Park, Maryland)
ABSTRACT A cooperatively controlled robotic system includes a main robot assembly, and an arm assembly comprising a proximal end and a distal end. The arm assembly is connected to the main robot assembly at the proximal end. The system also includes a tool assembly connected to the arm assembly at the distal end, a first force sensor between the distal end of the arm assembly and the tool assembly, and a second force sensor between the proximal end of the arm assembly and the main robot assembly. The system includes a control system that is configured to determine a force applied at the first force sensor based on a force detected by the second force sensor, and to compare the determined force to a force detected by the first force sensor to detect a failure of at least one of the first and second force sensors.
FILED Friday, June 10, 2016
APPL NO 15/179438
ART UNIT 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/30 (20160201) Original (OR) Class
A61B 2017/0003 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1676 (20130101)
B25J 13/085 (20130101)
B25J 19/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166379 Konofagou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Elisa E. Konofagou (New York, New York);  James J. Choi (Englewood, New Jersey)
ABSTRACT Systems and methods for opening a tissue to a target value using microbubbles are disclosed herein. In an embodiment of a method for opening a tissue to a target value using microbubbles, a region of the tissue is targeted for opening, an acoustic parameter corresponding to the target value is determined, and an ultrasound beam is applied to the target region at the acoustic parameter such that the tissue at the target region is opened to the target value with the microbubbles. The acoustic parameter can be selected to control an acoustic cavitation event and, in some embodiments, controlling an acoustic cavitation event can include controlling a location, number and/or magnitude of acoustic cavitation events.
FILED Thursday, May 26, 2016
APPL NO 15/165942
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/0071 (20130101)
A61B 8/481 (20130101)
A61B 8/0808 (20130101)
A61B 8/0816 (20130101)
A61B 17/225 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/0092 (20130101) Original (OR) Class
A61M 2202/0007 (20130101)
A61M 2205/058 (20130101)
A61M 2205/0244 (20130101)
A61M 2210/12 (20130101)
A61M 2210/0693 (20130101)
A61M 2250/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166542 Ros et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Alexandra Ros (Phoenix, Arizona);  Bahige G. Abdallah (Casa Grande, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Alexandra Ros (Phoenix, Arizona);  Bahige G. Abdallah (Casa Grande, Arizona)
ABSTRACT A microfluidic apparatus, systems and methods for microfluidic crystallization based on gradient mixing. In one embodiment, the apparatus includes (a) a first layer, (b) a plurality of first channels and a plurality of vacuum chambers both arranged in the first layer, where the plurality of vacuum chambers are each coupled to at least one of the first channels, (c) a membrane having first and second surfaces, where the first surface of the membrane is coupled to the first layer, (d) a second layer coupled to the second surface of the membrane, (e) a plurality of wells and a plurality of second channels both arranged in the second layer, where the wells are each coupled to at least one of the plurality of second channels and (f) a plurality of barrier walls each disposed in the plurality of second channels and arranged opposite to one of the plurality of vacuum chambers.
FILED Thursday, September 17, 2015
APPL NO 15/510126
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101)
B01L 3/502715 (20130101)
B01L 3/502738 (20130101)
B01L 3/502761 (20130101) Original (OR) Class
B01L 2200/0652 (20130101)
B01L 2300/16 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0654 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0848 (20130101)
B01L 2300/0861 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2300/0887 (20130101)
B01L 2300/0896 (20130101)
B01L 2400/049 (20130101)
B01L 2400/0424 (20130101)
B01L 2400/0487 (20130101)
B01L 2400/0655 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167193 Rosenthal et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
Division of Materials Research (DMR)
Office of The Director (OD)
Office of Experimental Program to Stimulate Competitive Research (EPSCOR)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Sandra J. Rosenthal (Nashville, Tennessee);  Toshia Wrenn (La Vergne, Tennessee)
ABSTRACT Disclosed herein are ferroelectric agglomerates and methods related thereto. In certain aspects, the ferroelectric agglomerates can be made from particles that have been treated with SbX3 or SbX5, wherein X is a halogen. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Wednesday, September 23, 2015
APPL NO 14/863388
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101) Original (OR) Class

Non-metallic Elements; Compounds Thereof;
C01B 19/007 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167326 Andersen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) ALBANY MEDICAL COLLEGE (Albany, New York)
ASSIGNEE(S) ALBANY MEDICAL COLLEGE (Albany, New York)
INVENTOR(S) Thomas T. Andersen (Albany, New York);  Herbert I. Jacobson (Albany, New York);  James A. Bennett (Delmar, New York);  Leroy Joseph (Brooklyn, New York);  Alberto Bryan (Philadelphia, Pennsylvania)
ABSTRACT The invention relates to compounds that are analogs of a cyclic peptide, cyclo[EKTOVNOGN], AFPep, that has anti-estrotrophic activity. The analogs of the invention include peptides and peptidomimetics that inhibit estrogen receptor-dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwanted estrogen induced cell proliferation, including breast cancer.
FILED Friday, January 29, 2016
APPL NO 15/010724
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 7/52 (20130101)
C07K 7/64 (20130101)
C07K 14/4715 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167362 Lee et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Byoung Hoon Lee (Goleta, California);  Alan J. Heeger (Santa Barbara, California)
ABSTRACT A method of fabricating an organic field effect transistor (OFET), including forming a source contact, a drain contact, and a gate connection to a channel comprising semiconducting polymers, wherein the gate connection applies a field to the semiconductor polymers across a dielectric layer to modulate conduction along the semiconducting polymers between the source contact and the drain contact; and treating the semiconducting polymers, wherein the treating includes a chemical treatment that controls a carrier density, carrier mobility, threshold voltage, and/or contact resistance of the OFET.
FILED Friday, September 02, 2016
APPL NO 15/256160
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/126 (20130101) Original (OR) Class
C08G 2261/18 (20130101)
C08G 2261/51 (20130101)
C08G 2261/92 (20130101)
C08G 2261/124 (20130101)
C08G 2261/146 (20130101)
C08G 2261/212 (20130101)
C08G 2261/228 (20130101)
C08G 2261/1412 (20130101)
C08G 2261/1646 (20130101)
C08G 2261/3241 (20130101)
C08G 2261/3246 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0036 (20130101)
H01L 51/0043 (20130101)
H01L 51/0512 (20130101)
H01L 51/0545 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167488 Keasling et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jay D. Keasling (Berkeley, California);  Christopher B. Eiben (Berkeley, California)
ABSTRACT Cells comprising a heterologous metabolic pathway are configured to produce a terpene product containing non-multiples of five carbon, particularly wherein the pathway comprises heterologous Lepidoptera insect juvenile hormone biosynthetic pathway enzymes of the insect's mevalonate pathway.
FILED Friday, November 03, 2017
APPL NO 15/803735
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0006 (20130101)
C12N 9/88 (20130101)
C12N 9/90 (20130101)
C12N 9/1025 (20130101)
C12N 9/1029 (20130101)
C12N 9/1085 (20130101)
C12N 9/1205 (20130101)
C12N 15/52 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 5/007 (20130101) Original (OR) Class
C12P 9/00 (20130101)

Enzymes
C12Y 101/01034 (20130101)
C12Y 203/0301 (20130101)
C12Y 203/01009 (20130101)
C12Y 205/01001 (20130101)
C12Y 207/01036 (20130101)
C12Y 402/03027 (20130101)
C12Y 503/03002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167490 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Pinghua Liu (Newton, Massachusetts);  Heng Song (Allston, Massachusetts);  Wen Hu (Boston, Massachusetts)
ASSIGNEE(S) Ergo Health LLC (Newton, Massachusetts)
INVENTOR(S) Pinghua Liu (Newton, Massachusetts);  Heng Song (Allston, Massachusetts);  Wen Hu (Boston, Massachusetts)
ABSTRACT The present disclosure relates to the production of ergothioneine through either in vitro enzymatic transformations or fermentations using microbials created by metabolic engineering. Also disclosed are transformed cells useful in such methods and ergothioneine produced by such methods. Transformed cells of the disclosure are capable of converting histidine and cysteine or hercynine and cysteine into ergothioneine in greater efficiency than the untransformed wild-type cells.
FILED Friday, December 20, 2013
APPL NO 14/428061
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Heterocyclic Compounds
C07D 233/42 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/52 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 13/04 (20130101)
C12P 17/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168297 Johnson, Jr. et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Alan T. Johnson, Jr. (Philadelphia, Pennsylvania);  Ye Lu (Philadelphia, Pennsylvania);  Brett R. Goldsmith (Philadelphia, Pennsylvania);  Nicholas J. Kybert (Haverford, Pennsylvania)
ABSTRACT The present invention provides a broad response single-stranded DNA-graphene chemical sensor device. The present invention also provides methods for improving the ability of graphene to work as a chemical sensor by using single-stranded DNA as a sensitizing agent.
FILED Monday, August 17, 2015
APPL NO 14/827691
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/414 (20130101)
G01N 27/3278 (20130101)
G01N 27/4145 (20130101) Original (OR) Class
G01N 33/5308 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168309 Motayed et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia);  GEORGE MASON UNIVERSITY (Fairfax, Virginia);  THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERICE (Washington, District of Columbia);  GEORGE MASON UNIVERSITY (Fairfax, Virginia);  THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia)
INVENTOR(S) Abhishek Motayed (Rockville, Maryland);  Geetha Aluri (Clifton Park, New York);  Albert V. Davydov (North Potomac, Maryland);  Mulpuri V. Rao (Fairfax Station, Virginia);  Vladimir P. Oleshko (Gaithersburg, Maryland);  Ritu Bajpai (Santa Clara, California);  Mona E. Zaghloul (Bethesda, Maryland)
ABSTRACT A nanostructure sensing device comprises a semiconductor nanostructure having an outer surface, and at least one of metal or metal-oxide nanoparticle clusters functionalizing the outer surface of the nanostructure and forming a photoconductive nanostructure/nanocluster hybrid sensor enabling light-assisted sensing of a target analyte.
FILED Thursday, February 08, 2018
APPL NO 15/891699
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/127 (20130101)
G01N 33/004 (20130101)
G01N 33/005 (20130101)
G01N 33/0031 (20130101)
G01N 33/0037 (20130101)
G01N 33/0042 (20130101)
G01N 33/0044 (20130101)
G01N 33/0047 (20130101)
G01N 33/0049 (20130101)
G01N 33/0054 (20130101)
G01N 33/0057 (20130101) Original (OR) Class

Technologies for Adaptation to Climate Change
Y02A 50/245 (20180101)
Y02A 50/246 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168317 Mak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Michael Mak (Boston, Massachusetts);  David Erickson (Ithaca, New York)
ABSTRACT The present invention relates to a microfluidic device, a microfluidic system, and methods for tracking single cells, multiple cells, single cell lineages, and multiple cell lineages in series and/or in parallel. The microfluidic device comprises a substrate having one microfluidic channel formed therein or a plurality of microfluidic channels formed therein and arranged in parallel. The microfluidic system comprises: a microfluidic device according to the present invention; a cell loading reservoir in fluid communication with the inlet end of each microfluidic channel of the microfluidic device; and an outlet reservoir in fluid communication with the outlet end of each microfluidic channel of the microfluidic device. The present invention also relates to a high throughput microfluidic system and a kit for tracking single cells and/or single cell lineages.
FILED Monday, June 10, 2013
APPL NO 14/406310
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502761 (20130101)
B01L 2200/0668 (20130101)
B01L 2300/087 (20130101)
B01L 2300/0861 (20130101)
B01L 2400/086 (20130101)
B01L 2400/0457 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
G01N 33/5005 (20130101) Original (OR) Class
G01N 33/5008 (20130101)
G01N 2500/10 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168341 Lam et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) EMORY UNIVERSITY (Atlanta, Georgia);  CHILDREN'S HEALTHCARE OF ATLANTA, INC. (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, None);  Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia)
INVENTOR(S) Wilbur A. Lam (Decatur, Georgia);  David Myers (Atlanta, Georgia);  Yongzhi Qiu (Atlanta, Georgia)
ABSTRACT A device may be configured to allow individual measuring of at least one property of at least one cell, such as measuring a contraction force of a platelet. The device may include a plurality of wells. Each well may include a hydrogel layer, the hydrogel layer including a hydrogel having a top surface that includes a pattern of cell interaction regions. The wells may differ in stiffness properties of the hydrogel and/or biochemical conditions. Each cell interaction region may include a group of at least two cell interaction sites. The spacing between each cell interaction region may be greater than a spacing between the at least two cell interaction sites of each cell interaction region. In this way, cell-cell interactions may be reduced and thereby increasing number of individual cells capable of being measured.
FILED Monday, March 10, 2014
APPL NO 14/202946
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/86 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10169498 Desbrun et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Mathieu Desbrun (Pasadena, California);  Fernando De Goes (Berkeley, California)
ABSTRACT The use of power diagrams in accordance with embodiments of the invention enable particle based fluid simulation. One embodiment includes a processor, a memory containing a model of a fluid, where the fluid is broken into a set of cells each defining a volume with boundaries that are relative to a distance of a set of points, where the process is configured by the power particle application to: calculate a plurality of forces acting on the set of cells, move the set of cells within the model of the fluid based upon the plurality of forces, and update the model of the fluid with a new set of cells.
FILED Thursday, April 14, 2016
APPL NO 15/099312
ART UNIT 2617 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/5009 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10169535 Mentis
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF MARYLAND BALTMORE COUNTY (Baltimore, Maryland)
ASSIGNEE(S) The University of Maryland, Baltimore County (Baltimore, Maryland)
INVENTOR(S) Helena Mentis (Baltimore, Maryland)
ABSTRACT The invention relates to annotating live video during endoscopy medical procedures.
FILED Tuesday, January 19, 2016
APPL NO 15/001218
ART UNIT 2485 — Recording and Compression
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/0005 (20130101)
A61B 1/00041 (20130101)

Electric Digital Data Processing
G06F 3/017 (20130101)
G06F 3/167 (20130101)
G06F 3/0482 (20130101)
G06F 3/04842 (20130101)
G06F 19/321 (20130101) Original (OR) Class

Information Storage Based on Relative Movement Between Record Carrier and Transducer
G11B 27/34 (20130101)

Pictorial Communication, e.g Television
H04N 2005/2255 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10169833 Barooah et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Prabir Barooah (Gainesville, Florida);  Sean Meyn (Gainesville, Florida)
ABSTRACT Techniques for providing ancillary services to a power grid using customer premises such as commercial buildings. The techniques may involve receiving a regulation signal from a grid operator that is specific to a commercial building and modifying power consumption by at least one power consumption component in the building based on the regulation signal. The power consumption component may be a fan of a Heating, Ventilation, and Air Conditioning (HVAC) system. Conducted experiments demonstrate that up to 15% of fan power capacity may be deployed for regulation purposes while maintaining indoor temperature deviation to no more than 0.2° C. The regulation signal may be tracked in a frequency band from about 4 seconds to 10 minutes.
FILED Wednesday, May 14, 2014
APPL NO 14/120367
ART UNIT 2199 — Interprocess Communication and Software Development
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 50/06 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 307/406 (20150401)
Y10T 307/549 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170678 McKinley et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ian McKinley (Venice, California);  Laurent G. Pilon (Sherman Oaks, California)
ABSTRACT A system for generating electrical energy includes a thermal source, an electric field source, a stress source, a piezoelectric component, and a cycle controller coupled to the thermal source, the electric field source, and the stress source. The cycle controller provides control signals to the thermal source, the electric field source, and the stress source to repeatedly cycle the piezoelectric component through the sequence: (a) application of: a first temperature, a first electric field, and a first stress; (b) application of: the first temperature, a second electric field greater than the first electric field, and the first stress; (c) application of: a second temperature, the second electric field, and a second stress greater than the first stress; and (d) application of: the second temperature, the first electric field, and the second stress.
FILED Wednesday, March 19, 2014
APPL NO 14/219958
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 37/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170946 Krishnasamy et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Persimmon Technologies, Corp. (Wakefield, Massachusetts)
ASSIGNEE(S) Persimmon Technologies Corporation (Wakefield, Massachusetts)
INVENTOR(S) Jayaraman Krishnasamy (Boxborough, Massachusetts);  Martin Hosek (Lowell, Massachusetts);  Dennis Poole (East Derry, New Hampshire)
ABSTRACT An apparatus includes a motor having a rotor; and a stator, where the rotor is located at least partially in a rotor receiving area of the stator, where the stator includes at least one coil winding and teeth, where the at least one coil winding is located on at least some of the teeth, where the teeth include a first set of the teeth and a second set of the teeth, where the teeth of the first set of teeth are longer in a radial direction from the rotor receiving area than the teeth of the second set of teeth.
FILED Monday, February 01, 2016
APPL NO 15/011802
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Dynamo-electric Machines
H02K 1/146 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10171086 McCaughan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Adam N. McCaughan (Cambridge, Massachusetts);  Karl K. Berggren (Arlington, Massachusetts)
ABSTRACT A three-terminal device that exhibits transistor-like functionality at cryogenic temperatures may be formed from a single layer of superconducting material. A main current-carrying channel of the device may be toggled between superconducting and normal conduction states by applying a control signal to a control terminal of the device. Critical-current suppression and device geometry are used to propagate a normal-conduction hotspot from a gate constriction across and along a portion of the main current-carrying channel. The three-terminal device may be used in various superconducting signal-processing circuitry.
FILED Tuesday, March 11, 2014
APPL NO 14/775118
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 39/10 (20130101)
H01L 39/12 (20130101)
H01L 39/025 (20130101)
H01L 39/125 (20130101)
H01L 39/126 (20130101)
H01L 39/145 (20130101)

Pulse Technique
H03K 19/20 (20130101)
H03K 19/195 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 10166244 Simard
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Maryland, Baltimore (Baltimore, Maryland);  The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University of Maryland, Baltimore (Baltimore, Maryland);  The United States of America as Represented by the Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S) J. Marc Simard (Baltimore, Maryland)
ABSTRACT The present invention concerns protection of an organ or tissue outside of the central nervous system following an ischemic episode. In particular aspects, the invention concerns organ preservation for transplantation, angina pectoris, kidney reperfusion injury, and so forth. In specific embodiments, the organ is subjected to an inhibitor of an NCCa-ATP channel that is regulated by SUR1. Exemplary inhibitors include sulfonylurea compounds, such as glibenclamide, for example.
FILED Monday, December 05, 2016
APPL NO 15/369056
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/57 (20130101) Original (OR) Class
A61K 31/427 (20130101)
A61K 31/565 (20130101)
A61K 38/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6872 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166271 Mulugeta et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Million Mulugeta (Culver City, California);  Lixin Wang (Los Angeles, California);  Yvette Taché (Los Angeles, California);  Jean Rivier (La Jolla, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California)
INVENTOR(S) Million Mulugeta (Culver City, California);  Lixin Wang (Los Angeles, California);  Yvette Taché (Los Angeles, California);  Jean Rivier (La Jolla, California)
ABSTRACT This disclosure reveals that cyclic corticotrophin releasing factor (CRF) antagonist peptides (such as astressin B, its functional fragments, and their derivatives) induce hair growth and prevent hair loss in vivo. This important discovery enables, for instance, methods of promoting hair growth, and methods of treating hair loss (such as the hair loss that occurs normally in some individuals or that is the result of a health disorder or therapeutic treatment). Exemplary cyclic CRF antagonist peptides useful in the disclosed methods are provided throughout the disclosure.
FILED Wednesday, June 20, 2007
APPL NO 11/766012
ART UNIT 1676 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/17 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10166277 Rome et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The United States of America represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Leonard H. Rome (Los Angeles, California);  Valerie A. Kickhoefer (Sherman Oaks, California);  Sherven Sharma (Oakland, California);  Steven M. Dubinett (Los Angeles, California);  Isaac Yang (Los Angeles, California);  Linda M. Liau (Los Angeles, California);  Kathleen A. Kelly (Pacific Palisades, California);  Jian Yang (Los Angeles, California);  Upendra K. Kar (Oakland, California);  Cheryl Champion (Greensboro, Georgia);  Janina Jiang (Los Angeles, California)
ABSTRACT The invention relates to compositions of vault complexes for use as adjuvants for stimulating a cellular immune response to an antigen, for example a tumor antigen, and methods of using the vault complexes in the treatment of diseases, such as cancer.
FILED Monday, September 05, 2016
APPL NO 15/256683
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5052 (20130101)
A61K 38/19 (20130101)
A61K 38/45 (20130101)
A61K 38/177 (20130101)
A61K 38/195 (20130101)
A61K 39/0011 (20130101) Original (OR) Class
A61K 47/646 (20170801)
A61K 47/6925 (20170801)
A61K 2039/57 (20130101)
A61K 2039/64 (20130101)
A61K 2039/572 (20130101)
A61K 2039/575 (20130101)
A61K 2039/645 (20130101)
A61K 2039/6031 (20130101)
A61K 2039/6081 (20130101)
A61K 2039/55516 (20130101)

Peptides
C07K 14/00 (20130101)
C07K 14/77 (20130101)
C07K 2319/00 (20130101)
C07K 2319/01 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2710/14043 (20130101)

Enzymes
C12Y 204/0203 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167265 Reddy
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Raju Reddy (Cheswick, Pennsylvania)
ABSTRACT Disclosed is a compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of:
X1-L-X2 wherein L is a linking moiety comprising an enone; and X1 and X2 are each independently an optionally-substituted N-heterocycle. Also disclosed are method for treating pulmonary conditions and other organ or system conditions with the compounds.
FILED Thursday, November 30, 2017
APPL NO 15/828163
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 239/26 (20130101)
C07D 239/30 (20130101)
C07D 239/34 (20130101)
C07D 239/38 (20130101)
C07D 239/42 (20130101)
C07D 239/47 (20130101)
C07D 239/52 (20130101)
C07D 241/12 (20130101)
C07D 241/16 (20130101)
C07D 241/18 (20130101)
C07D 241/20 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 10167379 Barnell et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Cornerstone Research Group, Inc. (Miamisburg, Ohio)
ASSIGNEE(S) Cornerstone Research Group, Inc. (Miamisburg, Ohio)
INVENTOR(S) Thomas J. Barnell (Dayton, Ohio);  Sean P. Garrigan (Beavercreek, Ohio);  Michael D. Rauscher (Beavercreek, Ohio);  Benjamin A. Dietsch (Dayton, Ohio);  Gary N. Cupp (Waynesville, Ohio)
ABSTRACT Embodiments of a hybrid fiber layup used to form a fiber-reinforced polymeric composite, and a fiber-reinforced polymeric composite produced therefrom are disclosed. The hybrid fiber layup comprises one or more dry fiber strips and one or more prepreg fiber strips arranged side by side within each layer, wherein the prepreg fiber strips comprise fiber material impregnated with polymer resin and the dry fiber strips comprise fiber material without impregnated polymer resin.
FILED Thursday, January 18, 2018
APPL NO 15/874458
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 70/02 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2063/00 (20130101)
B29K 2067/00 (20130101)
B29K 2079/085 (20130101)
B29K 2507/04 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2009/00 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 7/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10169847 Heineck et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) James Thomas Heineck (San Jose, California);  Daniel William Banks (Carmichael, California);  Edward Treanor Schairer (Palo Alto, California);  Paul Stewart Bean (Lancaster, California);  Edward Andrew Haering, Jr. (Lancaster, California);  Brett Arnold Pauer (Tehachapi, California);  Brittany Joan Martin (Edwards, California);  David Nils Larson (Lancaster, California)
ABSTRACT An air-to-air background-oriented Schlieren system and method for measuring and rendering visible density changes in air that cause a refractive index change by an airborne vehicle. A sensor aircraft equipped with a high-speed visible spectrum camera travels at low airspeed on a predetermined route and on a level altitude over a background having consistent contrast and sunlight reflectivity. The target aircraft, traveling on the same predetermined route but at an altitude between the sensor aircraft and the ground (background) passes beneath the sensor aircraft. The camera on the sensor aircraft captures a series of images including a reference image immediately before the target aircraft enters the image frame followed by several data images as the target aircraft passes through the image frame. The data images are processed to calculate density gradients around the target aircraft. These density gradients include shockwaves, vortices, engine exhaust, and wakes. Air density gradients cause a refractive index change in the fluid and a slight distortion in the background pattern of the data image. Image processing that compares the data image to the reference image yields the difference caused by the density gradient.
FILED Friday, August 05, 2016
APPL NO 15/229555
ART UNIT 2485 — Recording and Compression
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 47/08 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6202 (20130101)

Image Data Processing or Generation, in General
G06T 5/002 (20130101) Original (OR) Class
G06T 5/50 (20130101)
G06T 7/0026 (20130101)
G06T 2207/10032 (20130101)
G06T 2207/20224 (20130101)

Pictorial Communication, e.g Television
H04N 7/183 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170843 Thomson et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Mark W. Thomson (Pasadena, California);  Richard E. Hodges (Pasadena, California);  Nacer E. Chahat (Pasadena, California);  Jonathan Sauder (Pasadena, California);  Yahya Rahmat-Samii (Pasadena, California);  Brian Hirsh (Long Beach, California)
ABSTRACT A deployable antenna is described. The antenna comprises a mesh attached to foldable ribs, a hub and a sub-reflector. The antenna can be stowed in a tight space for launching in space, and later deployed by extending out of its container. The antenna is designed to work in the Ka band or other bands and can increase data rates and function as a radio antenna.
FILED Friday, May 27, 2016
APPL NO 15/167703
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/288 (20130101)
H01Q 13/02 (20130101)
H01Q 15/162 (20130101)
H01Q 19/19 (20130101) Original (OR) Class
H01Q 19/132 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10171756 Moore et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Andrew J. Moore (Williamsburg, Virginia);  Matthew R. Schubert (Newport News, Virginia)
ABSTRACT Systems and methods for identifying a fault in an electrical distribution system may include capturing an image of a corona event associated with a component of the electrical distribution system and processing the image of the corona event to identify the center and boundary of the corona event. An overlay for display with the image of the corona event may be generated, where the overlay identifying at least a center of the corona event and may be displayed to a user via a user interface device. In some cases, an unmanned aerial vehicle may comprise one or more image sensors capable of capturing the image of the corona event and communicate the images to a remote device for processing and display to the user. The image captured by the image sensors may include an ultraviolet image, a visible spectrum image, an infrared image, or a combination of image types.
FILED Wednesday, April 27, 2016
APPL NO 15/139808
ART UNIT 2487 — Recording and Compression
CURRENT CPC
Image Data Processing or Generation, in General
G06T 3/0087 (20130101)
G06T 2207/10032 (20130101)
G06T 2207/10048 (20130101)

Transmission
H04B 7/18506 (20130101)

Pictorial Communication, e.g Television
H04N 5/33 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 10169288 Colgan et al.
FUNDED BY
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Evan G. Colgan (Chestnut Ridge, New York);  Monty M. Denneau (Brewster, New York);  Daniel M. Kuchta (Patterson, New York)
ABSTRACT Node interconnect architectures to implement a high performance supercomputer are provided. For example, a node interconnect architecture for connecting a multitude of nodes (or processors) of a supercomputer is implemented using an all-to-all electrical and optical connection network which provides two independent communication paths between any two processors of the supercomputer, wherein a communication path includes at most two electrical links and one optical link.
FILED Wednesday, April 27, 2016
APPL NO 15/140034
ART UNIT 2874 — Optics
CURRENT CPC
Electric Digital Data Processing
G06F 15/161 (20130101)
G06F 15/163 (20130101)
G06F 15/173 (20130101) Original (OR) Class
G06F 15/17337 (20130101)

Transmission
H04B 10/2503 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 5/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10171105 Singh et al.
FUNDED BY
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Deepak K. Singh (Apex, North Carolina);  Monty M. Denneau (Brewster, New York);  Brian M. Rogers (Durham, North Carolina)
ABSTRACT Technical solutions are described for determining a population count of an input bit-string. In an example, a population count circuit receives a single n-bit input data word including of bits A[n−1:0]. The population count circuit isolates a pair of 4-bit nibbles. The population count circuit includes a carryless counter circuit that determines a pair of counts of 1s, one for each 4-bit nibble. The population circuit further includes an adder circuit that determines the population count by summing the pair of counts of 1s from the carryless counter circuit, where the adder circuit determines the most significant bit (MSB) of the sum based on the MSBs of the counts of 1s only, without depending on carry propagation.
FILED Thursday, August 25, 2016
APPL NO 15/247192
ART UNIT 2182 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 7/00 (20130101)
G06F 7/607 (20130101)

Coding; Decoding; Code Conversion in General
H03M 7/46 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10171281 Dickson et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Timothy O. Dickson (Danbury, Connecticut);  Bongjin Kim (Falcon Heights, Minnesota)
ABSTRACT A four-level pulse amplitude modulation transmitter and corresponding method are provided. The transmitter includes a most significant bit processing section and a least significant bit processing section. The transmitter further includes at least one termination resistor connected to respective outputs of the processing sections to provide a transmitter output. Each of the processing sections include a set of retiming latches arranged in a parallel for aligning input parallel data and providing parallel aligned latched outputs responsive to one phase of a quarter-rate four-phase quadrature clock. Each of the processing sections further includes a serializer for serializing the parallel aligned latched outputs to provide a serialized output using quarter-rates of the quarter-rate four-phase quadrature clock. Each of the processing sections also include an output driver for driving the serialized output.
FILED Wednesday, August 02, 2017
APPL NO 15/667251
ART UNIT 2632 — Digital Communications
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 25/03878 (20130101)
H04L 27/01 (20130101)
H04L 27/364 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 10167498 Henry et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Applied Research Associates, Inc. (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Alyssa Catharyn Henry (Arlington, Virginia);  David Judson Ross (Silver Spring, Maryland)
ABSTRACT Methods of detecting the presence of toxins in a sample using electrophoretic separations and of performing electrophoretic separation of complex samples are provided. The method of detecting the presence of toxins includes reacting a sample and a substrate with a signaling enzyme which converts the substrate to the product in a reaction medium, introducing a run buffer into a separation channel having an inlet end, selectively introducing at least one of the substrate and the product of the reaction medium into the inlet end of the separation channel, electrophoretically separating the substrate and the product, and determining the rate of conversion of the substrate to the product, wherein a change in the rate of conversion is indicative of the presence of toxins. The method of performing electrophoretic separations of complex samples having charged particulates and oppositely charged analytes comprising introducing a run buffer into a separation channel having an inlet end, selectively introducing the oppositely charged analytes in the complex sample into the separation channel, and electrophoretically separating the charged particulates and the oppositely charged analytes. Additionally, a device for varying with respect to time the bulk flow of a fluid in a separation channel of an electrophoretic device having a buffer reservoir in fluid contact with the separation channel is provided. The device includes a pressure sensor in fluid contact with a buffer reservoir, a high pressure reservoir in selective fluidic communication with the buffer reservoir, a low pressure reservoir in selective fluidic communication with the buffer reservoir and in fluidic communication with the high pressure reservoir, and a pumping device for pumping a gas from the low pressure reservoir to the high pressure reservoir.
FILED Tuesday, January 05, 2016
APPL NO 14/988373
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101)
B01L 3/502715 (20130101)
B01L 3/502723 (20130101)
B01L 3/502738 (20130101)
B01L 3/502753 (20130101)
B01L 2300/14 (20130101)
B01L 2400/082 (20130101)
B01L 2400/0421 (20130101)
B01L 2400/0605 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/46 (20130101) Original (OR) Class
C12Q 1/527 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4476 (20130101)
G01N 27/44704 (20130101)
G01N 27/44791 (20130101)
G01N 2333/918 (20130101)
G01N 2333/988 (20130101)
G01N 2550/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168309 Motayed et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia);  GEORGE MASON UNIVERSITY (Fairfax, Virginia);  THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERICE (Washington, District of Columbia);  GEORGE MASON UNIVERSITY (Fairfax, Virginia);  THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia)
INVENTOR(S) Abhishek Motayed (Rockville, Maryland);  Geetha Aluri (Clifton Park, New York);  Albert V. Davydov (North Potomac, Maryland);  Mulpuri V. Rao (Fairfax Station, Virginia);  Vladimir P. Oleshko (Gaithersburg, Maryland);  Ritu Bajpai (Santa Clara, California);  Mona E. Zaghloul (Bethesda, Maryland)
ABSTRACT A nanostructure sensing device comprises a semiconductor nanostructure having an outer surface, and at least one of metal or metal-oxide nanoparticle clusters functionalizing the outer surface of the nanostructure and forming a photoconductive nanostructure/nanocluster hybrid sensor enabling light-assisted sensing of a target analyte.
FILED Thursday, February 08, 2018
APPL NO 15/891699
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/127 (20130101)
G01N 33/004 (20130101)
G01N 33/005 (20130101)
G01N 33/0031 (20130101)
G01N 33/0037 (20130101)
G01N 33/0042 (20130101)
G01N 33/0044 (20130101)
G01N 33/0047 (20130101)
G01N 33/0049 (20130101)
G01N 33/0054 (20130101)
G01N 33/0057 (20130101) Original (OR) Class

Technologies for Adaptation to Climate Change
Y02A 50/245 (20180101)
Y02A 50/246 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 10168420 Fluhler et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Herbert U. Fluhler (Huntsville, Alabama);  Michael J. Guthrie (Huntsville, Alabama)
ASSIGNEE(S)
INVENTOR(S) Herbert U. Fluhler (Huntsville, Alabama);  Michael J. Guthrie (Huntsville, Alabama)
ABSTRACT A new radar is disclosed possessing desirable attributes for close range, short event time, high data rate sensing and data collection applications. A Continuous Wave (CW) or very high Pulse Repetition Frequency (PRF) Pulse based waveform, nominally with very high duty cycle (i.e. highly range aliased), is amplified and transmitted from one antenna, and after reflection from targets of interest, is received by one or a plurality of receive antennas. Both transmit and receive are optimally synchronous and phase coherent. The received signals are down converted to baseband leaving only the Doppler frequency from the targets of interest. These Doppler frequencies change over Fast Time as a function of the specific target trajectory and speed. A bank of time dependent correlation filters, each tuned to a different trajectory hypothesis, are used to integrate up the Doppler Signal for targets traveling the hypothesized trajectory, and decorrelated those that are not.
FILED Wednesday, July 15, 2015
APPL NO 14/800669
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 11/02 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/414 (20130101) Original (OR) Class
G01S 13/52 (20130101)
G01S 13/536 (20130101)
G01S 13/9023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10170946 Krishnasamy et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Persimmon Technologies, Corp. (Wakefield, Massachusetts)
ASSIGNEE(S) Persimmon Technologies Corporation (Wakefield, Massachusetts)
INVENTOR(S) Jayaraman Krishnasamy (Boxborough, Massachusetts);  Martin Hosek (Lowell, Massachusetts);  Dennis Poole (East Derry, New Hampshire)
ABSTRACT An apparatus includes a motor having a rotor; and a stator, where the rotor is located at least partially in a rotor receiving area of the stator, where the stator includes at least one coil winding and teeth, where the at least one coil winding is located on at least some of the teeth, where the teeth include a first set of the teeth and a second set of the teeth, where the teeth of the first set of teeth are longer in a radial direction from the rotor receiving area than the teeth of the second set of teeth.
FILED Monday, February 01, 2016
APPL NO 15/011802
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Dynamo-electric Machines
H02K 1/146 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Treasury (TREASURY) 

US 10166741 Ying et al.
FUNDED BY
Department of the Treasury (TREASURY)
APPLICANT(S) The United States of America, as Represented by the Secretary of Treasury (Washington, District of Columbia)
ASSIGNEE(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE TREASURY (Washington, District of Columbia)
INVENTOR(S) Tsineng Tony Ying (Gaithersburg, Maryland);  Richard R. Robidoux (Washington, District of Columbia)
ABSTRACT An alloy includes: steel; manganese; aluminum; and silicon in an amount such that the alloy has an electrical conductivity from 2% IACS to 6% IACS measured in accordance with ASTM E1004-09 (2009).
FILED Thursday, July 27, 2017
APPL NO 15/661141
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 15/04 (20130101)
B32B 15/013 (20130101)
B32B 15/015 (20130101) Original (OR) Class
B32B 15/043 (20130101)
B32B 2255/06 (20130101)
B32B 2255/205 (20130101)

Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 6/005 (20130101)
C21D 6/008 (20130101)

Alloys
C22C 38/002 (20130101)
C22C 38/02 (20130101)
C22C 38/04 (20130101)
C22C 38/06 (20130101)
C22C 2202/02 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 18/32 (20130101)
C23C 30/00 (20130101)
C23C 30/005 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/26 (20150115)
Y10T 428/1291 (20150115)
Y10T 428/12882 (20150115)
Y10T 428/12903 (20150115)
Y10T 428/12917 (20150115)
Y10T 428/12924 (20150115)
Y10T 428/12931 (20150115)
Y10T 428/12937 (20150115)
Y10T 428/12972 (20150115)
Y10T 428/12979 (20150115)
Y10T 428/12993 (20150115)
Y10T 428/24942 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 10165773 Neff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
U.S. State Government
State of Oregon
APPLICANT(S) Jennifer A. Neff (Rancho Santa Margarita, California);  Joseph McGuire (Corvallis, Oregon);  Pranav Joshi (Bangalore, India)
ASSIGNEE(S) Allvivio Vascular, Inc. (Lake Forest, California);  State of Oregon acting by and through the State Board of Higher Ed. on Behalf of Oregon State Univ. (Corvallis, Oregon)
INVENTOR(S) Jennifer A. Neff (Rancho Santa Margarita, California);  Joseph McGuire (Corvallis, Oregon);  Pranav R. Joshi (Bangalore, India)
ABSTRACT The invention is based on the recognition that known antimicrobial compounds, such as nisin or other lantibiotics, can be made to form a long lasting antimicrobial surface coating by linking the peptide with a block polymer, such as PLURONIC® F108 or an end group activated polymer (EGAP) in a manner to form a flexible tether and/or entrap the peptide. The entrapped peptide provides antimicrobial action by early release from entrapment while the tethered peptide provides longer lasting antimicrobial protection. Antimicrobial gels and foams may be prepared using the antimicrobial peptide containing block copolymers.
FILED Wednesday, August 20, 2014
APPL NO 14/464589
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 25/10 (20130101) Original (OR) Class
A01N 25/10 (20130101)
A01N 25/10 (20130101)
A01N 25/34 (20130101)
A01N 25/34 (20130101)
A01N 25/34 (20130101)
A01N 37/46 (20130101)
A01N 43/90 (20130101)
A01N 43/90 (20130101)
A01N 63/02 (20130101)
A01N 63/02 (20130101)
A01N 2300/00 (20130101)

Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 3/3463 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 47/48215 (20130101)
A61K 47/48992 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/232 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 65/3348 (20130101)
C08G 2650/58 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 9/08 (20130101)
C08K 2201/013 (20130101)

Compositions of Macromolecular Compounds
C08L 71/02 (20130101)
C08L 71/02 (20130101)
C08L 2205/05 (20130101)
C08L 2666/02 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/1352 (20150115)
Y10T 428/1376 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 10166280 Tam et al.
FUNDED BY
APPLICANT(S) EPITOPIX LLC (Willmar, Minnesota)
ASSIGNEE(S) EPITOPIX, LLC (Willmar, Minnesota)
INVENTOR(S) Patricia E. Tam (Golden Valley, Minnesota);  Michael Nathan Harris (Los Alamos, New Mexico);  Timothy James Tripp (Eden Prairie, Minnesota);  Sandra Lobo (Sandy Hook, Connecticut)
ABSTRACT The present invention provides isolated polypeptides isolatable from a Bacillus spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.
FILED Thursday, June 08, 2017
APPL NO 15/617541
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/07 (20130101) Original (OR) Class
A61K 2039/57 (20130101)
A61K 2039/70 (20130101)
A61K 2039/55561 (20130101)
A61K 2039/55566 (20130101)

Peptides
C07K 14/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10167075 Kennedy et al.
FUNDED BY
APPLICANT(S) The Boeing Company (Seal Beach, California)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Dennis K. Kennedy (Mesa, Arizona);  Zach K. Stahlecker (Chandler, Arizona);  Saul Opie (Mesa, Arizona)
ABSTRACT A joint assembly includes a first component formed from a first material and a second component including a portion that extends at least partially into the first component and that has an uneven outer profile. The first material is configured to form the first component into a shape that is substantially complementary to a shape of the portion to facilitate restricting movement of the second component in an axial direction.
FILED Tuesday, June 25, 2013
APPL NO 13/926377
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 11/26 (20130101) Original (OR) Class
B64C 27/473 (20130101)
B64C 2027/4736 (20130101)

Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing
F16B 11/002 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49337 (20150115)
Y10T 403/4966 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10168209 Spencer et al.
FUNDED BY
APPLICANT(S) RAYTHEON COMPANY (Waltham, Massachusetts)
ASSIGNEE(S) RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S) Susan B. Spencer (Rolling Hills Estates, California);  Lacy G. Cook (El Segundo, California);  Andrew L. Bullard (Manhattan Beach, California);  John F. Silny (Playa Vista, California)
ABSTRACT Aspects and embodiments are generally directed to modular imaging spectrometer assemblies and methods of operation thereof. In one example, a modular imaging spectrometer assembly includes foreoptics to receive electromagnetic radiation and produce a real exit pupil, the foreoptics having a first f-number, a first imaging spectrometer to receive and disperse the electromagnetic radiation into a first plurality of spectral bands at a first image plane, the first imaging spectrometer having a second f-number independent of the first f-number, a second imaging spectrometer separated from the first imaging spectrometer, the second imaging spectrometer to receive and disperse the electromagnetic radiation into a second plurality of spectral bands, the second imaging spectrometer having a third f-number independent of the first f-number, and at least one slit aperture positioned to receive the electromagnetic radiation from the real exit pupil and direct the electromagnetic radiation to the first and second imaging spectrometers.
FILED Friday, April 07, 2017
APPL NO 15/481834
ART UNIT 2877 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/0202 (20130101) Original (OR) Class
G01J 3/0208 (20130101)
G01J 3/0235 (20130101)
G01J 3/0291 (20130101)
G01J 3/0294 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10169297 Buchanan
FUNDED BY
APPLICANT(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
ASSIGNEE(S) HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas)
INVENTOR(S) Brent Buchanan (Palo Alto, California)
ABSTRACT In one example in accordance with the present disclosure a resistive memory array is described. The array includes a number of resistive memory elements to receive a common-valued read signal. The array also includes a number of multiplication engines to perform a multiply operation by receiving a memory element output from a corresponding resistive memory element, receiving an input signal, and generating a multiplication output based on a received memory element output and a received input signal. The array also includes an accumulation engine to sum multiplication outputs from the number of multiplication engines.
FILED Thursday, April 16, 2015
APPL NO 15/500486
ART UNIT 2182 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 7/50 (20130101)
G06F 7/523 (20130101)
G06F 7/5443 (20130101)
G06F 17/16 (20130101) Original (OR) Class
G06F 2207/4802 (20130101)

Static Stores
G11C 7/1006 (20130101)
G11C 13/004 (20130101)
G11C 2213/77 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

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Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, January 01, 2019.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

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FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190101.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital