FedInvent™ Patents
Patent Details for Tuesday, January 08, 2019
This page was updated on Monday, March 27, 2023 at 05:42 AM GMT
Department of Health and Human Services (HHS)
| US 10172333 | Rogers et al. |
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| FUNDED BY |
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| APPLICANT(S) | Exemplar Genetics, LLC (Sioux Center, Iowa) |
| ASSIGNEE(S) | EXEMPLAR GENETICS, LLC (Sioux Center, Iowa) |
| INVENTOR(S) | Christopher Rogers (Coralville, Iowa); John Swart (Sioux Center, Iowa) |
| ABSTRACT | The present invention provides transgenic, large non-human animal models of cancer, as well as methods of using such animal models in the identification and characterization of therapies for cancer. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/776564 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class A01K 67/0278 (20130101) A01K 2217/15 (20130101) A01K 2217/052 (20130101) A01K 2217/072 (20130101) A01K 2227/108 (20130101) A01K 2267/0331 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8509 (20130101) C12N 2015/8572 (20130101) C12N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172555 | Cam et al. |
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| APPLICANT(S) | Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Bruce Cam (Stanford, California); David B. Camarillo (Aptos, California); Lyndia Chun Wu (Stanford, California) |
| ABSTRACT | Provided is a device for placement on a human subject to detect impacts on the human subject. The device includes a base member, one or more engagement sensors to detect whether the device is properly placed on the human subject, and one or more motion sensors to detect the kinematics of the human subject. The device also includes a processing unit that includes methodology to detect false positives such as chewing, dropping, and throwing. |
| FILED | Thursday, March 06, 2014 |
| APPL NO | 14/199716 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0004 (20130101) A61B 5/038 (20130101) A61B 5/0205 (20130101) A61B 5/682 (20130101) Original (OR) Class A61B 5/746 (20130101) A61B 5/1121 (20130101) A61B 5/02438 (20130101) A61B 5/6817 (20130101) A61B 5/6819 (20130101) A61B 5/7267 (20130101) A61B 5/7282 (20130101) A61B 2562/0257 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 71/085 (20130101) A63B 2071/0627 (20130101) A63B 2220/34 (20130101) A63B 2220/40 (20130101) A63B 2220/803 (20130101) A63B 2220/805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172558 | Negi et al. |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Sandeep Negi (Salt Lake City, Utah); Rajmohan Bhandari (Salt Lake City, Utah); Mobashir Hasan Shandi (Salt Lake City, Utah) |
| ABSTRACT | A high aspect ratio shadow mask and a method of making and using the high aspect ratio shadow mask can provide multiple conductive trace pathways along high aspect ratio electrodes. The high aspect ratio shadow mask can include a substantially planar base layer and a plurality of hollow high aspect ratio projections extending from the substantially planar base layer. The high aspect ratio shadow mask can further include a plurality of openings along the hollow projections which define trace deposition patterns. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/261648 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/685 (20130101) Original (OR) Class A61B 5/04001 (20130101) A61B 2562/046 (20130101) A61B 2562/125 (20130101) A61B 2562/0209 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/0502 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 1/008 (20130101) B81B 2201/055 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00111 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/003 (20130101) C25D 1/08 (20130101) C25D 5/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172581 | Nishino et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Mizuki Nishino (Newton, Massachusetts); Bruce E. Johnson (Brookline, Massachusetts); Hiroto Hatabu (Newton, Massachusetts); Suzanne E. Dahlberg (Chelmsford, Massachusetts) |
| ABSTRACT | The present invention provides method of assessing tumor growth. |
| FILED | Tuesday, September 09, 2014 |
| APPL NO | 14/917720 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/50 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 2800/52 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172791 | Ma et al. |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Minglin Ma (Ithaca, New York); Daniel G. Anderson (Framingham, Massachusetts); Robert S. Langer (Newton, Massachusetts); Omid Veiseh (Cambridge, Massachusetts); Joshua Charles Doloff (Quincy, Massachusetts); Delai Chen (Cambridge, Massachusetts); Christian J. Kastrup (Vancouver, Canada); Arturo Jose Vegas (Cambridge, Massachusetts) |
| ABSTRACT | Biomedical devices for implantation with decreased pericapsular fibrotic overgrowth are disclosed. The device includes biocompatible materials and has specific characteristics that allow the device to elicit less of a fibrotic reaction after implantation than the same device lacking one or more of these characteristic that are present on the device. Biocompatible hydrogel capsules encapsulating mammalian cells having a diameter of greater than 1 mm, and optionally a cell free core, are disclosed which have reduced fibrotic overgrowth after implantation in a subject. Methods of treating a disease in a subject are also disclosed that involve administering a therapeutically effective amount of the disclosed encapsulated cells to the subject. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/776639 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) Original (OR) Class A61K 9/4833 (20130101) A61K 9/4866 (20130101) A61K 9/5036 (20130101) A61K 9/5078 (20130101) A61K 9/5089 (20130101) A61K 35/39 (20130101) A61K 45/06 (20130101) A61K 2035/126 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172795 | Gao et al. |
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| APPLICANT(S) | University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Xiang Gao (Pittsburgh, Pennsylvania); Song Li (Wexford, Pennsylvania); Peter Wipf (Pittsburgh, Pennsylvania); Michael Wayne Epperly (Pittsburgh, Pennsylvania); Joel S. Greenberger (Sewickley, Pennsylvania) |
| ABSTRACT | A method of creating a formulation for a compound includes determining a compound interactive agent comprising at least one group that interacts with the compound, creating a carrier agent by conjugating at least one compound interactive domain comprising the at least one group that interacts with the compound with at least one hydrophilic domain, and combining the compound and the carrier agent to create the formulation. Creating the carrier agent may further include conjugating the at least one compound interactive domain with at least one hydrophobic domain so that the at least one compound interactive domain is positioned between the at least one hydrophilic domain and the at least one hydrophobic domain. |
| FILED | Thursday, December 12, 2013 |
| APPL NO | 14/651840 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) Original (OR) Class A61K 9/1271 (20130101) A61K 31/45 (20130101) A61K 31/337 (20130101) A61K 31/704 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172817 | Tavazoie et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Sohail Tavazoie (New York, New York); Jia M. Loo (New York, New York) |
| ABSTRACT | The present invention discloses novel agents and methods for diagnosis and treatment of colon cancer. Also disclosed are related arrays, kits, and screening methods. |
| FILED | Thursday, June 22, 2017 |
| APPL NO | 15/630024 |
| ART UNIT | 1674 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/197 (20130101) Original (OR) Class A61K 31/337 (20130101) A61K 31/513 (20130101) A61K 31/555 (20130101) A61K 31/4168 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 31/7072 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172827 | McKnight et al. |
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| APPLICANT(S) | Board of Regents of The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Steven L. McKnight (Dallas, Texas); Joseph M. Ready (Carrollton, Texas); Andrew A. Pieper (Iowa City, Iowa); Jef K. De Brabander (Flower Mound, Texas) |
| ABSTRACT | This invention relates generally to stimulating neurogenesis (e.g., post-natal neurogenesis, e.g., post-natal hippocampal neurogenesis) and protecting from neuron cell death. |
| FILED | Friday, January 15, 2016 |
| APPL NO | 14/996596 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/44 (20130101) A61K 31/403 (20130101) Original (OR) Class A61K 31/404 (20130101) A61K 31/415 (20130101) A61K 31/422 (20130101) A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/4155 (20130101) A61K 31/4192 (20130101) A61K 31/4439 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/18 (20180101) A61P 25/28 (20180101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 209/86 (20130101) C07D 209/88 (20130101) C07D 401/06 (20130101) C07D 401/12 (20130101) C07D 403/06 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 413/06 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172831 | Taylor et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Palmer Taylor (La Jolla, California); Zoran Radic (La Jolla, California); Valery Fokin (Lo Jolla, California) |
| ABSTRACT | Provided are N-alkyl imidazole 2-aldoximes, including cationic imidazolium and uncharged tertiary imidazole aldoximes, and compositions and methods for making and using them, including methods for reactivating human butyrylcholinesterase (hBChE) or acetylcholinesterase (hAChE) inhibited by organophosphate (OP). By administration of a composition of the invention, the inactive or conjugated hBChE-OP or hAChE-OP is reactivated and the catalytic cycle of turnover and inactivation of the OP is completed; and in alternative embodiments, secondary mechanisms of reversible protection of hBChE and hAChE from irreversible inactivation by OPs and reactivation of tissue AChE also contribute to overall efficacy. |
| FILED | Wednesday, October 15, 2014 |
| APPL NO | 15/028669 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4164 (20130101) Original (OR) Class A61K 31/4439 (20130101) A61K 31/5377 (20130101) A61K 38/465 (20130101) A61K 45/06 (20130101) Enzymes C12Y 301/01008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172839 | Longo et al. |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Valter D. Longo (Playa del Rey, California); Stefano Di Biase (Redondo Beach, California) |
| ABSTRACT | A method of alleviating or treating symptoms of cancer and/or effects of chemotherapy or of kinase inhibitors includes a step of identifying a subject having cancer. A reduced caloric diet is administered to the subject for a first time period, the reduced caloric diet providing at most 1000 kcal per day. A kinase inhibitor is administered to the subject. |
| FILED | Friday, March 27, 2015 |
| APPL NO | 14/671622 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) Original (OR) Class A61K 31/436 (20130101) A61K 31/475 (20130101) A61K 31/475 (20130101) A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172855 | Wise et al. |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas) |
| INVENTOR(S) | John G. Wise (Allen, Texas); Pia D. Vogel (Allen, Texas); Frances K. Brewer (Waxahachie, Texas); Courtney A. Follit (Dallas, Texas) |
| ABSTRACT | The present disclosure provides a method of treating a subject that is resistant to one or more drugs by identifying a subject having one or more drug resistant cells; administering to the subject a pharmaceutically effective amount of an inhibitor compound, and contacting one or more drug resistant cells with the inhibitor compound to reduce the export of the inhibitor compound from the one or more drug resistant tumor cells and to block the transport of drug(s) from the one or more drug resistant cells. |
| FILED | Friday, January 13, 2017 |
| APPL NO | 15/406036 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) A61K 31/353 (20130101) A61K 31/4196 (20130101) A61K 31/4525 (20130101) A61K 31/5025 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172863 | Chiosis et al. |
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| APPLICANT(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| ASSIGNEE(S) | Sloan-Kettering Institute For Cancer Research (New York, New York) |
| INVENTOR(S) | Gabriela Chiosis (New York, New York); Tony Taldone (Forest Hills, New York); Weilin Sun (Princeton, New Jersey) |
| ABSTRACT | The present application provides substituted purine derivatives and related compounds of the formulas shown. These compounds are useful as inhibitors of HSP90, and hence in the treatment of related diseases. (Formulae) Z1-Z3, Xa-Xc, X2, X4, Y and R are as defined in the specification. |
| FILED | Thursday, April 21, 2016 |
| APPL NO | 15/135121 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) Original (OR) Class A61K 31/538 (20130101) Heterocyclic Compounds C07D 473/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172870 | Reddy |
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| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Doodipala Samba Reddy (College Station, Texas) |
| ABSTRACT | The present invention provides new compositions and methods for treating and/or reversing organophosphate intoxication, manifested by both cholinergic and non-cholinergic crisis, in a mammal resulting from exposure to organophosphate compounds. The neurosteroidal compounds of this invention are those having the general structural formula of pregnane, androstane, 19-norandrostanes, and norpregnane with further moieties as defined herein. These compounds include, but are not limited to, ganaxolone, pregnanolone, and androstanediol and their analogs, salts and prodrugs. The present invention further relates to combining a therapeutically effective amount of a neurosteroidal compound with a standard organophosphate antidote (e.g. atropine, pralidoxime). The data suggests that neurosteroids are effective or more effective than benzodiazepines, whether given earlier or later than 40-min (up to several hours) after organophosphate compound exposure. Neurosteroids are effective to attenuate long-term neuropsychiatric deficits caused by organophosphate exposure. |
| FILED | Tuesday, September 01, 2015 |
| APPL NO | 15/508233 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/57 (20130101) Original (OR) Class A61K 31/565 (20130101) A61K 31/573 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172873 | Slusher et al. |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Barbara Slusher (Kingsville, Maryland); Rana Rais (West Friendship, Maryland); XUHANG Li (Clarksville, Maryland) |
| ABSTRACT | Methods and compounds are disclosed for treating inflammatory bowel disease (IBD) by using Prostate Specific Membrane Antigen (PSMA) inhibitors. |
| FILED | Thursday, August 06, 2015 |
| APPL NO | 15/502009 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/02 (20130101) A61K 9/0031 (20130101) A61K 9/0053 (20130101) A61K 31/194 (20130101) A61K 31/662 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172880 | Osborn et al. |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Mark Osborn (Minneapolis, Minnesota); Jakub Tolar (Minneapolis, Minnesota); Bruce Robert Blazar (Golden Valley, Minnesota); Daniel Voytas (Falcon Heights, Minnesota) |
| ABSTRACT | The invention is directed to transcription activator-like effector nuclease (TALEN)-mediated DNA editing of disease-causing mutations in the context of the human genome and human cells to treat patients with compromised genetic disorders. |
| FILED | Wednesday, June 15, 2016 |
| APPL NO | 15/182773 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Original (OR) Class A61K 31/7088 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172893 | Uchida et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Hiroaki Uchida (Kanagawa, Japan); Justus B. Cohen (Allison Park, Pennsylvania); Joseph C. Glorioso, III (Pittsburgh, Pennsylvania); Paola Grandi (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention provides a recombinant herpes simplex virus (HSV), comprising (a) a mutation of the glycoprotein B (gB) at position 285 or 549, (b) a plurality of copies of one or more microRNA target sequences inserted into a locus of an HSV gene required for HSV replication, wherein said target sequence is the reverse complement of microRNA miR-124 and wherein said target sequence is present in the ICP4 gene, and (c) a transgene encoding a matrix metalloproteinase. The present invention also provides a method of killing a cancerous cell using a recombinant HSV according to the invention and a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a recombinant HSV according to the invention. |
| FILED | Wednesday, June 07, 2017 |
| APPL NO | 15/616585 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/763 (20130101) Original (OR) Class Peptides C07K 14/005 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16621 (20130101) C12N 2710/16622 (20130101) C12N 2710/16632 (20130101) C12N 2710/16641 (20130101) C12N 2710/16643 (20130101) C12N 2710/16645 (20130101) C12N 2710/16662 (20130101) C12N 2710/16671 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172905 | Anderson et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kenneth C. Anderson (Wellesley, Massachusetts); James E. Bradner (Weston, Massachusetts); Edward Franklin Greenberg (Cleveland, Ohio); Teru Hideshima (Brookline, Massachusetts); Nicholas Paul Kwiatkowski (Brookline, Massachusetts); Ralph Mazitschek (Belmont, Massachusetts); Stuart L. Schreiber (Boston, Massachusetts); Jared Shaw (Davis, California); Stephen J. Haggarty (Gloucester, Massachusetts) |
| ABSTRACT | The invention relates to methods of treating protein degradation disorders, such cellular proliferative disorders (e.g., cancer) and protein deposition disorders (e.g., neurodegenerative disorders). The invention provides methods and pharmaceutical compositions for treating these diseases using aggresome inhibitors or combinations of aggresome inhibitors and proteasome inhibitors. The invention further relates to methods and pharmaceutical compositions for treating multiple myeloma. New HDAC/TDAC inhibitors and aggresome inhibitors are also provided as well as synthetic methodologies for preparing these compounds. |
| FILED | Monday, January 09, 2017 |
| APPL NO | 15/401902 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/35 (20130101) A61K 31/69 (20130101) A61K 31/357 (20130101) A61K 31/422 (20130101) A61K 31/4965 (20130101) A61K 38/05 (20130101) Original (OR) Class A61K 38/50 (20130101) A61K 45/06 (20130101) A61K 49/0008 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172911 | Mezey et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Eva M. Mezey (Rockville, Maryland); Balazs Mayer (Budakeszi, Hungary); Krisztian Nemeth (Budapest, Hungary); Miklos Krepuska (Rockville, Maryland) |
| ABSTRACT | Disclosed are methods of modulating erythropoiesis with arginine vasopressin receptor 1B (AVPR1B) molecules, such as AVPR1B agonists or antagonists. In one example, a method of stimulating erythropoiesis is disclosed including administering an effective amount of an AVPR1B stimulatory molecule to a subject in need thereof, thereby stimulating erythropoiesis. Also disclosed is a method of stimulating hematopoetic stem cell (HSC) proliferation which includes administering an effective amount of an AVPR1B stimulatory molecule to a subject in need thereof, thereby stimulating HSC proliferation. A method of inhibiting HSC proliferation including administering an effective amount of an AVPR1B inhibitory molecule to a subject in need thereof, thereby inhibiting HSC proliferation is provided. |
| FILED | Wednesday, October 01, 2014 |
| APPL NO | 15/022531 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/465 (20130101) A61K 31/465 (20130101) A61K 38/11 (20130101) Original (OR) Class A61K 38/11 (20130101) A61K 38/1816 (20130101) A61K 38/1816 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172915 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Zhiquan Zhang (Durham, North Carolina); Mihai V. Podgoreanu (Chapel Hill, North Carolina); Qing Ma (Durham, North Carolina); David S. Warner (Chapel Hill, North Carolina); Mark F. Newman (Durham, North Carolina) |
| ABSTRACT | The present invention provides a method of treating, ameliorating or inhibiting sirtuin-associated disorders and/or conditions in a subject in need thereof, by administering to the subject an effective amount of an ANXA1 peptide. |
| FILED | Monday, October 20, 2014 |
| APPL NO | 14/519000 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172923 | Feghali-Bostwick et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Carol A. Feghali-Bostwick (Mt Pleasant, South Carolina); Yukie Yamaguchi (Kanagawa, Japan) |
| ABSTRACT | C-terminal endostatin polypeptides are disclosed herein. Polynucleotides encoding these polypeptide, host cells transformed with the polynucleotides, and methods of using these polypeptides and polynucleotides are disclosed. Uses of these polypeptide, polynucleotides and expression vectors include the treatment of fibrosis in a subject. Thus, methods are provided for treating fibrosis, including fibrosis of the skin and/or the lung. |
| FILED | Tuesday, December 20, 2016 |
| APPL NO | 15/385705 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/08 (20130101) A61K 38/39 (20130101) Original (OR) Class Peptides C07K 7/06 (20130101) C07K 14/47 (20130101) C07K 14/78 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172934 | Kawaoka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Gabriele Neumann (Madison, Wisconsin); Jihui Ping (Madison, Wisconsin) |
| ABSTRACT | The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, that confer enhanced growth in cells in culture, such as MDCK cells, or in eggs. |
| FILED | Thursday, May 11, 2017 |
| APPL NO | 15/593039 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16121 (20130101) C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172938 | Kiick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kristi L. Kiick (Rising Sun, Maryland); April M. Kloxin (Landenberg, Pennsylvania); Prathamesh M. Kharkar (Newark, Delaware); Raja Sivamani (Sacramento, California); Emanual Maverakis (Sacramento, California) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kristi L. Kiick (Rising Sun, Maryland); April M. Kloxin (Landenberg, Pennsylvania); Prathamesh M. Kharkar (Newark, Delaware); Raja Sivamani (Sacramento, California); Emanual Maverakis (Sacramento, California) |
| ABSTRACT | A responsive hydrogel-based material may be used as a carrier system for the in situ delivery of various cargo substances, including bioactive moieties. The hydrogel structure, which includes photodegradable and thioether moieties in its three dimensional network, enables finely tuned local release of cargo substances as a function of the in vivo tissue environment (e.g., enzyme concentration or reducing environment) and externally applied stimuli (e.g., light) by selective spatiotemporal hydrogel degradation. |
| FILED | Tuesday, April 28, 2015 |
| APPL NO | 15/307701 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 41/0019 (20130101) A61K 41/0042 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/34 (20130101) A61K 47/42 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/3344 (20130101) C08G 65/33327 (20130101) C08G 2210/00 (20130101) C08G 2650/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172951 | Rangaramanujam et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan); The United States of America as Represented by the Secretary, Department of Health and Human Service (Washington, District of Columbia) |
| INVENTOR(S) | Kannan Rangaramanujam (Detroit, Michigan); Sujatha Kannan (Detroit, Michigan); Roberto Romero (Grosse Pointe, Michigan); Raghavendra S. Navath (Somerset, New Jersey); Hui Dai (Rochester Hills, Michigan); Anupa R. Menjoge (Hayward, California) |
| ABSTRACT | A nanodevice composition including N-acetyl cysteine linked to a dendrimer, such as a PAMAM dendrimer or a multiarm PEG polymer, is provided. Also provided is a nanodevice for targeted delivery of a compound to a location in need of treatment. The nanodevice includes a PAMAM dendrimer or multiarm PEG polymer, linked to the compound via a disulfide bond. There is provided a nanodevice composition for localizing and delivering therapeutically active agents, the nanodevice includes a PAMAM dendrimer or multiarm PEG polymer and at least one therapeutically active agent attached to the PAMAM dendrimer or multiarm PEG polymer. A method of site-specific delivery of a therapeutically active agent, by attaching a therapeutically active agent to a PAMAM dendrimer or multiarm PEG polymer using a disulfide bond, administering the PAMAM dendrimer or multiarm PEG polymer to a patient in need of treatment, localizing the dendrimer or multiarm PEG polymer to a site in need of treatment, and releasing the therapeutically active agent at the site in need of treatment. |
| FILED | Thursday, September 04, 2014 |
| APPL NO | 14/477725 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/57 (20130101) A61K 31/65 (20130101) A61K 31/198 (20130101) A61K 31/405 (20130101) A61K 31/573 (20130101) A61K 38/10 (20130101) A61K 47/60 (20170801) A61K 47/64 (20170801) A61K 47/595 (20170801) A61K 47/48215 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172956 | Duvall et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Craig L. Duvall (Nashville, Tennessee); Christopher E. Nelson (Nashville, Tennessee); James Kintzing (Nashville, Tennessee); Joshua M. Shannon (Nashville, Tennessee); Mukesh K. Gupta (Nashville, Tennessee); Scott A. Guelcher (Thompsons Station, Tennessee); Elizabeth J. Adolph (Nashville, Tennessee); Jeffrey M. Davidson (Nashville, Tennessee) |
| ABSTRACT | The presently-disclosed subject matter includes nanoparticles that comprise a plurality of assembled polymers. In some embodiments the polymers comprise a first block that includes hydrophilic monomers, the first block substantially forming an outer shell of the nanoparticle, and a second block that includes cationic monomers and hydrophobic monomers, the second block substantially forming a core of the nanoparticle. In some embodiments a polynucleotide is provided that is bound to the cationic monomers of the nanoparticle. The presently-disclosed subject matter also comprises methods for using the present nanoparticles to include RNAi in a cell as well as methods for making the present nanoparticles. |
| FILED | Monday, October 28, 2013 |
| APPL NO | 14/438596 |
| ART UNIT | 1674 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5138 (20130101) A61K 47/489 (20130101) Original (OR) Class A61K 47/48176 (20130101) A61K 47/48215 (20130101) A61K 47/48869 (20130101) A61K 48/00 (20130101) A61K 48/0041 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/34 (20130101) C08F 283/06 (20130101) C08F 2220/1825 (20130101) C08F 2438/03 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/126 (20130101) C08J 2353/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) C12N 15/113 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2310/351 (20130101) C12N 2320/30 (20130101) Enzymes C12Y 502/01008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172959 | Alhamadsheh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mamoun M Alhamadsheh (Stockton, California) |
| ASSIGNEE(S) | Mamoun M. Alhamadsheh (Stockton, California) |
| INVENTOR(S) | Mamoun M. Alhamadsheh (Stockton, California); Miki S. Park (Stockton, California); William K. Chan (Elk Grove, California); Xiaoling Li (Dublin, California); Sravan C. Penchala (Stockton, California); Mark R. Miller (Stockton, California) |
| ABSTRACT | A delivery system for active agents, and methods of making and using the systems, are provided. The delivery systems have (i) a ligand that is selective for an endogeneous plasma protein in the serum of a subject; and, (ii) a linker configured for operatively attaching the ligand covalently to an active agent to increase the half-life of the active agent in the serum. |
| FILED | Wednesday, March 01, 2017 |
| APPL NO | 15/446212 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/4745 (20130101) A61K 38/00 (20130101) A61K 47/64 (20170801) Original (OR) Class A61K 47/545 (20170801) A61K 49/0052 (20130101) Heterocyclic Compounds C07D 231/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172961 | Porotto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York); INSERM (Paris, France) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); INSERM (Paris, France) |
| INVENTOR(S) | Matteo Porotto (New York, New York); Anne Moscona (New York, New York); Branka Horvat (Lyons, France); Cyrille Mathieu (Lyons, France) |
| ABSTRACT | The present application relates to an inhibitor of fusion between a viral membrane from an enveloped virus and a cell membrane, where the viral membrane comprises a fusion mediating protein including a C-terminal peptide. The inhibitor comprises the C-terminal peptide of the fusion mediating protein from an enveloped virus and tocopherol or a derivative or pharmaceutically acceptable salt thereof attached to the C-terminal peptide. Also disclosed is a pharmaceutical composition including the inhibitor as well as methods of inhibiting viral fusion, blocking viral spread, and preventing or treating viral infection, with the inhibitor or pharmaceutical composition. |
| FILED | Thursday, May 07, 2015 |
| APPL NO | 15/330795 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 31/355 (20130101) A61K 38/162 (20130101) A61K 47/02 (20130101) A61K 47/10 (20130101) A61K 47/16 (20130101) A61K 47/24 (20130101) A61K 47/26 (20130101) A61K 47/42 (20130101) A61K 47/65 (20170801) Original (OR) Class A61K 47/551 (20170801) A61K 47/645 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172962 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Dong Wang (Omaha, Nebraska); Jindrich Kopecek (Salt Lake City, Utah); Scott C. Miller (Salt Lake City, Utah); Pavla Kopeckova (Salt Lake City, Utah) |
| ABSTRACT | This invention relates to biotechnology, more particularly, to water-soluble polymeric delivery systems for the imaging, evaluation and/or treatment of rheumatoid arthritis and other inflammatory diseases. Using modern MR imaging techniques, the specific accumulation of macromolecules in arthritic joints in adjuvant-induced arthritis in rats is demonstrated. The strong correlation between the uptake and retention of the MR contrast agent labeled polymer with histopathological features of inflammation and local tissue damage demonstrates the practical applications of the macromolecular delivery system of the invention. |
| FILED | Friday, January 19, 2018 |
| APPL NO | 15/875015 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/58 (20170801) A61K 49/0041 (20130101) A61K 49/0054 (20130101) Original (OR) Class A61K 49/128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172967 | Norenberg |
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| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Jeffrey P. Norenberg (Albuquerque, New Mexico) |
| ABSTRACT | A subject afflicted with a cancer or precancerous condition is treated by administering an agent that increases expression of somatostatin receptors, and a cytotoxic recognition ligand. In an alternative embodiment, somatostatin analogs, which are radiolabeled are used to treat cancer or precancerous conditions. |
| FILED | Wednesday, February 08, 2017 |
| APPL NO | 15/427355 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7068 (20130101) A61K 31/7068 (20130101) A61K 38/31 (20130101) A61K 38/31 (20130101) A61K 45/06 (20130101) A61K 51/08 (20130101) Original (OR) Class A61K 51/083 (20130101) A61K 51/088 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173074 | Li |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Harbor, Michigan) |
| INVENTOR(S) | Qiao Li (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to methods, systems, and compositions for treating and preventing cancer in a subject with the combination of radiation therapy and antigen presenting cells that have been exposed cancer stem cells or a portion thereof. In certain embodiments, the antigen presenting cells are dendritic cells that have been pulsed with ALDHhigh cancer stem cells. |
| FILED | Thursday, October 24, 2013 |
| APPL NO | 14/437064 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/0011 (20130101) A61K 45/06 (20130101) A61K 51/00 (20130101) A61K 2039/5154 (20130101) A61K 2039/5158 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1001 (20130101) Original (OR) Class A61N 5/1077 (20130101) A61N 2005/1024 (20130101) A61N 2005/1098 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173208 | Schrock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston College (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Richard R. Schrock (Winchester, Massachusetts); Annie J. King (Cambridge, Massachusetts); Yu Zhao (Brighton, Massachusetts); Margaret M. Flook (Cambridge, Massachusetts); Amir H. Hoveyda (Lincoln, Massachusetts) |
| ABSTRACT | The present invention relates generally to catalysts and processes for the Z-selective formation of internal olefin(s) from terminal olefin(s) via homo-metathesis reactions. |
| FILED | Thursday, January 05, 2017 |
| APPL NO | 15/399485 |
| ART UNIT | 1673 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/181 (20130101) B01J 31/1805 (20130101) B01J 31/1825 (20130101) B01J 31/2226 (20130101) B01J 31/2265 (20130101) B01J 31/2278 (20130101) B01J 31/2295 (20130101) Original (OR) Class B01J 2231/54 (20130101) B01J 2231/543 (20130101) B01J 2531/64 (20130101) B01J 2531/66 (20130101) B01J 2531/0266 (20130101) B01J 2531/0288 (20130101) B01J 2540/40 (20130101) B01J 2540/225 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/09 (20130101) Acyclic or Carbocyclic Compounds C07C 6/04 (20130101) C07C 6/04 (20130101) C07C 6/04 (20130101) C07C 6/04 (20130101) C07C 11/02 (20130101) C07C 13/28 (20130101) C07C 15/50 (20130101) C07C 41/30 (20130101) C07C 41/30 (20130101) C07C 43/166 (20130101) C07C 67/475 (20130101) C07C 67/475 (20130101) C07C 69/593 (20130101) C07C 209/64 (20130101) C07C 209/68 (20130101) C07C 209/68 (20130101) C07C 211/53 (20130101) C07C 303/40 (20130101) C07C 303/40 (20130101) C07C 311/18 (20130101) C07C 2531/18 (20130101) C07C 2531/22 (20130101) C07C 2601/14 (20170501) C07C 2601/16 (20170501) C07C 2602/10 (20170501) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) C07F 7/083 (20130101) C07F 11/00 (20130101) C07F 11/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173968 | Garneau-Tsodikova et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Sylvie Garneau-Tsodikova (Lexington, Kentucky); David S. Watt (Lexington, Kentucky) |
| ABSTRACT | Hydrazone compounds and pharmaceutical compositions including same are disclosed as having antifungal activity. Such compounds are useful for treating or preventing fungal conditions in a subject in need thereof by administering same. |
| FILED | Friday, July 07, 2017 |
| APPL NO | 15/644677 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 251/82 (20130101) C07C 251/86 (20130101) Original (OR) Class C07C 281/18 (20130101) C07C 2603/18 (20170501) Heterocyclic Compounds C07D 279/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173974 | Rodríguez Pierluissi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Abimael D. Rodríguez Pierluissi (San Juan, Puerto Rico); Karinel Nieves Merced (San Juan, Puerto Rico) |
| ASSIGNEE(S) | University of Puerto Rico (San Juan, Puerto Rico) |
| INVENTOR(S) | Abimael D. Rodríguez Pierluissi (San Juan, Puerto Rico); Karinel Nieves Merced (San Juan, Puerto Rico) |
| ABSTRACT | The marine natural product (−)-8,15-diisocyano-11(20)-amphilectene, isolated from the Caribbean sponge Svenzea flava, was used as scaffold to synthesize five new products, all of which were tested against laboratory strains of Plasmodium falciparum and Mycobacterium tuberculosis H37Rv. The scaffold contains two isocyanide units that are amenable to chemical manipulation, enabling them to be elaborated into a small library of sulfur and selenium compounds. The scaffold along with its isothio- and isoselenocyanate analogs has low to sub-micro molar antiplasmodial activity. |
| FILED | Monday, November 07, 2016 |
| APPL NO | 15/345402 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) A61P 33/00 (20180101) Acyclic or Carbocyclic Compounds C07C 331/02 (20130101) Original (OR) Class C07C 391/00 (20130101) C07C 2603/28 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173978 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Milton L. Brown (Brookeville, Maryland); Shujie Hou (Gaithersburg, Maryland); Partha Banerjee (Rockville, Maryland); Karishma Amin (San Francisco, California) |
| ABSTRACT | Small molecule carbazole compounds for use as androgen receptor inhibitors are provided herein. Also provided herein are methods for using the carbazole compounds in treating prostate cancer, including castration-resistant prostate cancer and enzalutamide-resistant prostate cancer. The methods include administering to a subject an effective amount of a compound or composition as described herein. |
| FILED | Tuesday, August 02, 2016 |
| APPL NO | 15/749383 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/403 (20130101) A61K 31/403 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 209/88 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173984 | Shen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | Binghui Shen (La Verne, California); Judith Campbell (Pasadena, California); Li Zheng (Arcadia, California); Hongzhi Li (Duarte, California); David Horne (Duarte, California); Jun Xie (Duarte, California); Kenneth Karanja (Maple Grove, Minnesota) |
| ABSTRACT | Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2. |
| FILED | Tuesday, January 09, 2018 |
| APPL NO | 15/866268 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 215/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173998 | Hoekstra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mycovia Pharmaceuticals, Inc. (Durham, North Carolina); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | Mycovia Pharmaceuticals, Inc. (Durham, North Carolina); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | William J. Hoekstra (Durham, North Carolina); Christopher M. Yates (Raleigh, North Carolina); Mark Behnke (Poolesville, Maryland); Asaf Alimardanov (North Bethesda, Maryland); Scott A. David (Huntsburg, Ohio); Douglas Franklin Fry (Euclid, Ohio) |
| ABSTRACT | The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof. |
| FILED | Thursday, March 19, 2015 |
| APPL NO | 15/126402 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 213/26 (20130101) C07D 213/38 (20130101) C07D 401/06 (20130101) Original (OR) Class C07D 405/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174008 | Tang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Weiping Tang (Middleton, Wisconsin); Xiaoxun Li (Mountain View, California) |
| ABSTRACT | Methods of making indole analogs using a rhodium-containing catalyst are described, along with methods of using the compounds to treat hyperglycemic, hyperlipidemic, or autoimmune disorders in mammals, and corresponding pharmaceutical compositions. Disclosed herein is a method of making indoles. The method comprises contacting a reactant of formula I wherein E is a protecting group, —SO2-Aryl, or —SO2-substituted-Aryl; and R and R2 are independently selected from the group consisting of hydrogen, halo, C1-C12-alkyl and aryl; with a rhodium(1)-containing catalyst. |
| FILED | Thursday, December 03, 2015 |
| APPL NO | 15/545858 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2265 (20130101) B01J 31/4046 (20130101) B01J 2231/325 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 37/10 (20130101) C07B 51/00 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 405/08 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/55 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174031 | Wipf et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Peter Wipf (Pittsburgh, Pennsylvania); Stephen D. Meriney (Pittsburgh, Pennsylvania); Mary Liang (Pittsburgh, Pennsylvania) |
| ABSTRACT | Embodiments of calcium channel agonists, as well as methods of making and using the calcium channel agonists, are disclosed. The disclosed calcium channel agonists and corresponding salt forms have a structure according to general formula I: wherein each bond depicted as “ |
| FILED | Thursday, September 21, 2017 |
| APPL NO | 15/711715 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/52 (20130101) A61K 31/53 (20130101) A61K 31/53 (20130101) A61K 31/375 (20130101) A61K 31/375 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 473/16 (20130101) Original (OR) Class C07D 487/04 (20130101) Technologies for Adaptation to Climate Change Y02A 50/469 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174072 | Satoskar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Abhay R. Satoskar (Upper Arlington, Ohio); James F. Fuchs (Columbus, Ohio); Alan Douglas Kinghorn (Columbus, Ohio); Li Pan (Upper Arlington, Ohio); Claudio M. Lezama-Davila (Columbus, Ohio); Eric Bachelder (Dublin, Ohio) |
| ABSTRACT | In one aspect, the invention relates methods and compositions for treating parasitic diseases, for example, leishmaniasis. In a further aspect, the compounds of the methods and compositions are isolated from Pentalinon andrieuxii. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, January 20, 2017 |
| APPL NO | 15/411249 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/10 (20130101) A61K 9/0019 (20130101) A61K 9/1075 (20130101) A61K 9/1271 (20130101) A61K 9/1273 (20130101) A61K 9/1647 (20130101) A61K 9/2018 (20130101) A61K 9/2054 (20130101) A61K 9/2059 (20130101) A61K 9/5153 (20130101) A61K 31/57 (20130101) A61K 31/575 (20130101) A61K 45/06 (20130101) A61K 47/34 (20130101) A61K 47/40 (20130101) A61K 47/44 (20130101) Steroids C07J 7/002 (20130101) C07J 9/00 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/409 (20180101) Y02A 50/411 (20180101) Y02A 50/414 (20180101) Y02A 50/415 (20180101) Y02A 50/492 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174077 | McKee et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Patrick A. McKee (Oklahoma City, Oklahoma); Kenneth W. Jackson (Edmond, Oklahoma); Kyung N. Lee (Oklahoma City, Oklahoma); Victoria J. Christiansen (Oklahoma City, Oklahoma) |
| ABSTRACT | The presently disclosed inventive concept(s) include inhibitors of antiplasmin cleaving enzyme (APCE) and fibroblast activation protein alpha (FAP) which can be used in various therapies related to disorders of fibrin and α2-antiplasmin and abnormal cell proliferation. The presently disclosed inventive concept(s) also include substrates of APCE and FAP, which may be used, for example, in screening methods for identifying such inhibitors. The presently disclosed inventive concept(s) further include, but are not limited to, methods of treating or inhibiting atherosclerosis and thrombus disorders by altering the ratios of types of plasma α2-antiplasmin and to methods of treating conditions involving abnormal cell proliferation such as cancers. |
| FILED | Monday, November 21, 2016 |
| APPL NO | 15/357435 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 5/02 (20130101) C07K 5/021 (20130101) C07K 5/081 (20130101) C07K 5/1019 (20130101) C07K 5/06026 (20130101) Original (OR) Class C07K 7/02 (20130101) C07K 14/8121 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174079 | Lambris et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | John D. Lambris (Philadelphia, Pennsylvania); Hongchang Qu (Carmel, Indiana); Daniel Ricklin (Therwil, Switzerland) |
| ABSTRACT | Compounds comprising peptides capable of binding C3 protein and inhibiting complement activation are disclosed. The compounds comprise compstatin analogs in which the N-terminus contains an added or substituted component that improves (1) the peptide's binding affinity to C3 or its fragments, (2) the peptide's solubility in aqueous liquids, (3) the peptide's plasma stability, (4) the peptide's in vivo retention and/or (5) the peptide's bioavailability, as compared with an unmodified compstatin peptide under equivalent conditions. Pharmaceutical compositions and methods of using the compounds are also disclosed. |
| FILED | Wednesday, April 19, 2017 |
| APPL NO | 15/491142 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/10 (20130101) A61K 38/12 (20130101) A61K 45/06 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 7/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174090 | Mohammadi et al. |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Moosa Mohammadi (Scarsdale, New York); Regina Goetz (New York, New York) |
| ABSTRACT | The present invention relates to chimeric proteins that include an N-terminus coupled to a C-terminus, where the N-terminus includes an N-terminal portion of fibroblast growth factor 21 (“FGF21”) and the C-terminus includes a C-terminal portion of fibroblast growth factor 19 (“FGF19”). The present invention also relates to pharmaceutical compositions including chimeric proteins according to the present invention, as well as methods for treating a subject suffering from diabetes, obesity, or metabolic syndrome, methods of treating a subject in need of increased FGF21-βKlotho-FGF receptor complex formation, methods of causing increased FGF21 receptor agonist-βKlotho-FGF receptor complex formation, and methods of screening for compounds with enhanced binding affinity for the βKlotho-FGF receptor complex involving the use of chimeric proteins of the present invention. |
| FILED | Monday, October 03, 2016 |
| APPL NO | 15/283862 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1825 (20130101) A61K 45/06 (20130101) Peptides C07K 14/50 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/21 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 2333/50 (20130101) G01N 2500/02 (20130101) G01N 2800/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174098 | Hinrichs et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Christian S. Hinrichs (Bethesda, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed is a synthetic T cell receptor (TCR) having antigenic specificity for an HLA-A2-restricted epitope of human papillomavirus (HPV) 16 E7, E711-19. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, and populations of cells are also provided. Antibodies, or an antigen binding portion thereof, and pharmaceutical compositions relating to the TCRs of the invention are also provided. Also disclosed are methods of detecting the presence of a condition in a mammal and methods of treating or preventing a condition in a mammal, wherein the condition is cancer, HPV 16 infection, or HPV-positive premalignancy. |
| FILED | Friday, May 29, 2015 |
| APPL NO | 15/313673 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1774 (20130101) Peptides C07K 14/7051 (20130101) Original (OR) Class C07K 16/2809 (20130101) C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 33/57484 (20130101) G01N 2333/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174114 | Goldenberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | David M. Goldenberg (Mendham, New Jersey); Hans J. Hansen (Picayune, Mississippi); Chien-Hsing Chang (Downingtown, Pennsylvania) |
| ABSTRACT | The present invention concerns compositions and methods of use of humanized anti-HLA-DR antibodies. In preferred embodiments, the antibodies induce apoptosis and inhibit proliferation of lymphoma cells without inducing CDC or ADCC. In more preferred embodiments, the humanized anti-HLA-DR antibodies bind to the same epitope of HLA-DR as, or compete for binding to HLA-DR with, a murine L243 antibody. Most preferably, the humanized anti-HLA-DR antibody exhibits a higher affinity for HLA-DR than the parental murine antibody. The humanized HLA-DR antibody is of use for therapy of various diseases such as cancer, autoimmune disease or immune dysregulatory function, and is of particular use for therapy of B cell lymphomas and leukemias. In most preferred embodiments, the humanized anti-HLA-DR antibody is capable of inducing at least partial remission of lymphomas that are resistant to other B cell antibodies, such as rituximab. |
| FILED | Wednesday, November 16, 2016 |
| APPL NO | 15/353141 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 47/6849 (20170801) A61K 47/6867 (20170801) A61K 51/1027 (20130101) A61K 51/1093 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/28 (20130101) C07K 16/2833 (20130101) Original (OR) Class C07K 16/2887 (20130101) C07K 16/4241 (20130101) C07K 19/00 (20130101) C07K 2317/24 (20130101) C07K 2317/52 (20130101) C07K 2317/56 (20130101) C07K 2317/71 (20130101) C07K 2317/73 (20130101) C07K 2317/75 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/732 (20130101) C07K 2317/734 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174120 | Buckanovich et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Ronald J Buckanovich (Ann Arbor, Michigan); George Coukos (Wynnewood, Pennsylvania); Andrea Facciabene (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention provides methods of treating and enhancing efficacy of immunotherapy for a solid tumor in a subject, comprising the step of contacting the subject with a compound or composition that modulates the expression or activity of ETRB, ET-1, ICAM-1, or another protein found herein to play a role in homing of T cells to a solid tumor. The present invention also provides methods of prognosticating a solid tumor in a subject, comprising the step of measuring an expression level of a protein found herein to play a role in homing of T cells to a solid tumor, or a nucleotide molecule encoding same. |
| FILED | Wednesday, January 20, 2016 |
| APPL NO | 15/001241 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/7105 (20130101) A61K 38/06 (20130101) Peptides C07K 16/2869 (20130101) Original (OR) Class C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2320/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 33/57492 (20130101) G01N 2333/726 (20130101) G01N 2333/70525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174132 | Boons et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| ASSIGNEE(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| INVENTOR(S) | Geert-Jan Boons (Athens, Georgia); Andre Venot (Boulder, Colorado); Sailaja Arungundram (Kirkland, Washington); Kanar al-Mafraji (Nijmegen, Netherlands) |
| ABSTRACT | The invention provides an efficient modular chemical synthesis for heparan sulfate oligosaccharides based on orthogonal protection strategies. Modular disaccharide building blocks, themselves the product of a novel combinatorial synthesis, are combined in numerous ways to produce a range of oligosaccharides. |
| FILED | Monday, June 29, 2015 |
| APPL NO | 14/754175 |
| ART UNIT | 1673 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 5/04 (20130101) C07H 15/04 (20130101) C07H 15/203 (20130101) C07H 23/00 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0075 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174243 | Greytak et al. |
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| FUNDED BY |
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| APPLICANT(S) | Andrew B. Greytak (Columbia, South Carolina); Wenhao Liu (Somerville, Massachusetts); Peter M. Allen (Cambridge, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts); Daniel G. Nocera (Winchester, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Andrew B. Greytak (Columbia, South Carolina); Wenhao Liu (Somerville, Massachusetts); Peter M. Allen (Cambridge, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts); Daniel G. Nocera (Winchester, Massachusetts) |
| ABSTRACT | A semiconductor nanocrystal can have a photoluminescent quantum yield of at least 90%, at least 95%, or at least 98%. The nanocrystal can be made by sequentially contacting a nanocrystal core with an M-containing compound and an X donor, where at least one of the M-containing compound and the X donor is substoichiometric with respect to forming a monolayer on the nanocrystal core. |
| FILED | Tuesday, August 24, 2010 |
| APPL NO | 12/862195 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/584 (20130101) Original (OR) Class C09K 11/883 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174289 | Wells et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | James Macormack Wells (Cincinnati, Ohio); Kyle William McCracken (Cincinnati, Ohio) |
| ABSTRACT | Disclosed are methods of inducing formation of a gastric cells and/or a gastric tissue, such as in the form of a gastric organoid. The formation of gastric cells and/or tissue may be carried out by the activating and/or inhibiting of one or more signaling pathways within a precursor cell. Also disclosed are methods for using the disclosed gastric cells, gastric tissues, and/or gastric organoids derived from precursor cells. |
| FILED | Wednesday, May 27, 2015 |
| APPL NO | 15/312939 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0679 (20130101) C12N 5/0697 (20130101) Original (OR) Class C12N 2501/11 (20130101) C12N 2501/16 (20130101) C12N 2501/113 (20130101) C12N 2501/115 (20130101) C12N 2501/119 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174290 | Shenk et al. |
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| FUNDED BY |
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| APPLICANT(S) | Thomas Shenk (Princeton, New Jersey); Nicole Gudleski O'Regan (Hatboro, Pennsylvania); Todd M. Greco (Philadelphia, Pennsylvania); Ileana M. Cristea (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Thomas Shenk (Princeton, New Jersey); Nicole Gudleski O'Regan (Hatboro, Pennsylvania); Todd M. Greco (Philadelphia, Pennsylvania); Ileana M. Cristea (Princeton, New Jersey) |
| ABSTRACT | A method for enhancing infectivity of HCMV virus particles is provided. |
| FILED | Friday, July 20, 2012 |
| APPL NO | 14/233810 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/25 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2710/16151 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174313 | Kartalov et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California); CURATE BIOSCIENCES LLC (San Diego, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California); CURATE BIOSCIENCES LLC (San Diego, California) |
| INVENTOR(S) | Emil P. Kartalov (Pasadena, California); Cheng-Chung Lee (Irvine, California); Paul Predki (Carlsbad, California) |
| ABSTRACT | Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation device can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation device can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation device can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device. Also included are methods for selectively isolating cellular material using the devices described herein, as are methods for biochemical analysis of individual regions of interest of cellular material using the devices described herein. Further included are methods of making masking arrays useful for the methods described herein. The micro-isolation devices can comprise a unique combination of barcodes in each microfluidics well, allowing two-dimensional mapping of genetic information. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/885736 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 2300/0816 (20130101) B01L 2300/0887 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1093 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 1/6874 (20130101) C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174315 | Krieg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Translate Bio MA, Inc. (Lexington, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Translate Bio MA, Inc. (Lexington, Massachusetts) |
| INVENTOR(S) | Arthur M. Krieg (Cambridge, Massachusetts); Romesh Subramanian (Framingham, Massachusetts); James McSwiggen (Arlington, Massachusetts); Jeannie T. Lee (Boston, Massachusetts) |
| ABSTRACT | Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of hemoglobin genes (HBB, HBD, HBE1, HBG1 or HBG2). Further aspects provide compositions and kits comprising single stranded oligonucleotides for activating or enhancing expression of hemoglobin genes. Methods for modulating expression of hemoglobin genes using the single stranded oligonucleotides are also provided. Further aspects of the invention provide methods for selecting a candidate oligonucleotide for activating or enhancing expression of hemoglobin genes. |
| FILED | Thursday, May 16, 2013 |
| APPL NO | 14/401201 |
| ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/712 (20130101) A61K 31/7088 (20130101) A61K 31/7125 (20130101) A61K 47/28 (20130101) A61K 47/64 (20170801) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) C07H 21/02 (20130101) C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/341 (20130101) C12N 2310/3231 (20130101) C12N 2310/3341 (20130101) C12N 2310/3521 (20130101) C12N 2310/3533 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174323 | Krieg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Translate Bio MA, Inc. (Lexington, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Translate Bio MA, Inc. (Lexington, Massachusetts) |
| INVENTOR(S) | Arthur M. Krieg (Cambridge, Massachusetts); Romesh Subramanian (Framingham, Massachusetts); James McSwiggen (Arlington, Massachusetts); Jeannie T. Lee (Boston, Massachusetts) |
| ABSTRACT | Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of ATP2A2. Further aspects provide compositions and kits comprising single stranded oligonucleotides for activating or enhancing expression of ATP2A2. Methods for modulating expression of ATP2A2 using the single stranded oligonucleotides are also provided. Further aspects of the invention provide methods for selecting a candidate oligonucleotide for activating or enhancing expression of ATP2A2. |
| FILED | Thursday, May 16, 2013 |
| APPL NO | 14/401214 |
| ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) C07H 21/02 (20130101) C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/52 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/321 (20130101) C12N 2310/351 (20130101) C12N 2310/3231 (20130101) C12N 2310/3513 (20130101) C12N 2310/3515 (20130101) C12N 2310/3521 (20130101) Enzymes C12Y 306/03008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174338 | Carrington et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | James C. Carrington (St. Louis, Missouri); Edwards Allen (O'Fallon, Missouri) |
| ABSTRACT | A method to generate siRNAs in vivo is described, as are constructs and compositions useful in the method. The method does not depend on the use of DNA or synthetic constructs that contain inverted duplications or dual promoters so as to form perfect or largely double-stranded RNA. Rather, the method depends on constructs that yield single-stranded RNA transcripts, and exploits endogenous or in vivo-produced miRNAs or siRNAs to initiate production of siRNAs. The miRNAs or siRNAs guide cleavage of the transcript and set the register for production of siRNAs (usually 21 nucleotides in length) encoded adjacent to the initiation cleavage site within the construct. The method results in specific formation of siRNAs of predictable size and register (phase) relative to the initiation cleavage site. The method can be used to produce specific siRNAs in vivo for inactivation or suppression of one or more target genes or other entities, such as pathogens. |
| FILED | Tuesday, May 24, 2016 |
| APPL NO | 15/163573 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/8218 (20130101) C12N 15/8245 (20130101) C12N 15/8246 (20130101) C12N 15/8247 (20130101) C12N 15/8251 (20130101) C12N 15/8261 (20130101) C12N 15/8271 (20130101) C12N 15/8274 (20130101) C12N 15/8279 (20130101) Original (OR) Class C12N 15/8281 (20130101) C12N 15/8283 (20130101) C12N 15/8285 (20130101) C12N 2310/14 (20130101) C12N 2320/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174341 | Glorioso, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); Joseph C. Glorioso, III (Pittsburgh, Pennsylvania); Justus Cohen (Pittsburgh, Pennsylvania); Yoshitaka Miyagawa (Pittsburgh, Pennsylvania); David Krisky (Sewickley, Pennsylvania); James Wechuck (Glenshaw, Pennsylvania); Darren Wolfe (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Joseph C. Glorioso, III (Pittsburgh, Pennsylvania); Justus Cohen (Pittsburgh, Pennsylvania); Yoshitaka Miyagawa (Pittsburgh, Pennsylvania); David Krisky (Sewickley, Pennsylvania); James Wechuck (Glenshaw, Pennsylvania); Darren Wolfe (Pittsburgh, Pennsylvania) |
| ABSTRACT | The invention provides a herpes simplex virus (HSV) vector that does not express toxic HSV genes in non-complementing cells and which comprises a genome comprising one or more transgenes, wherein the vector is capable of expression of a transgene for at least 28 days in non-complementing cells. The disclosed vectors include vectors having deletions in the genes ICP0, ICP4, TCP22, TCP27 and TCP47, or alternative inactivating mutations, or vectors which express one or more of these genes with modified kinetics. The invention also relates to viral stocks of the inventive vectors, compositions thereof suitable for use therapeutically or for in vitro applications, and methods relating thereto. In another aspect, the invention provides a complementing cell, in particular a U20S cell, engineered to express ICP4 and ICP27 when the cell is infected with HSV for the production of the inventive vector. Said cells are disclosed as naturally complementing ICP0. |
| FILED | Thursday, July 17, 2014 |
| APPL NO | 14/905708 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/763 (20130101) A61K 48/0066 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2710/16621 (20130101) C12N 2710/16643 (20130101) C12N 2710/16671 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174358 | Mandecki et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Wlodek Mandecki (Princeton Jct., New Jersey); Emanuel Goldman (Montclair, New Jersey); Maxim Chudaev (Providence, New Jersey) |
| ABSTRACT | The present invention provides a novel assay that allows high-throughput screening of chemical compounds for the inhibition of binding between EF-Tu and tRNA. |
| FILED | Friday, October 31, 2014 |
| APPL NO | 14/529618 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) C12Q 1/34 (20130101) Original (OR) Class Enzymes C12Y 306/05003 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 2500/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174377 | Whitcomb |
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| FUNDED BY |
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| APPLICANT(S) | University Of Pittsburgh Of The Commonwealth System Of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University Of Pittsburgh Of The Commonwealth System Of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | David C. Whitcomb (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present application discloses methods for predicting the risk of developing, or the presence of, recurrent acute pancreatitis and/or chronic pancreatitis, in a subject, by identifying the presence of an rs12688220 T allele, an rs7057398 T allele, and/or an rs10273639 C allele in a sample from the subject. The present application also discloses methods for treating or preventing pancreatitis in a human subject in need thereof. |
| FILED | Friday, May 08, 2015 |
| APPL NO | 14/707515 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/273 (20130101) A61B 5/055 (20130101) A61B 5/425 (20130101) A61B 6/032 (20130101) A61B 8/08 (20130101) A61B 17/00234 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/00 (20130101) A61M 27/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2535/131 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174381 | Chinnaiyan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Arul M. Chinnaiyan (Plymouth, Michigan); Dan Robinson (Ann Arbor, Michigan); Yi-Mi Wu (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure relates to methods of determining a treatment course of action. In particular, the present disclosure relates to mutations in the gene encoding estrogen receptor and their association with responsiveness to estrogen therapies for cancer. |
| FILED | Tuesday, October 14, 2014 |
| APPL NO | 14/513501 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/721 (20130101) C07K 14/70567 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) G01N 33/57442 (20130101) G01N 2333/723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174382 | Buechler et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame (Notre Dame, Indiana); Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | University of Notre Dame (Sound Bend, Indiana); Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Steven Buechler (Granger, Indiana); Sunil Badve (Indianapolis, Indiana); Yesim Gokmen-Polar (Indianapolis, Indiana) |
| ABSTRACT | A genetic biomarker panel is provided for prognosing late onset ER+ breast cancer relapse, in a breast cancer survivor patient. Kits are also provided for measuring levels or the presence of an identified panel of genetic biomarkers. Methods are also provided for identifying a breast cancer survivor patient at a relatively high risk of suffering a breast cancer relapse within 8 years of diagnosis, and therefore suitable for treatment with an aggressive chemotherapeutic regimen. The method may also be used for identifying a breast cancer survivor patient not at high risk of suffering a breast cancer relapse within 8 years of diagnosis, and thus not suitable for treatment with an aggressive chemotherapeutic regimen. The genetic biomarker panel includes an oligonucleotide/nucleic acid sequence specific for the following genes: MKI67, SPAG5, ESPL1, PLK1, or a genetic panel for MKI67, SPAG5, ESPL1, PLK1 and PGR. |
| FILED | Wednesday, May 13, 2015 |
| APPL NO | 14/711566 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175195 | Bashir et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rashid Bashir (Champaign, Illinois); Bala Murali Venkatesan (Champaign, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Rashid Bashir (Champaign, Illinois); Bala Murali Venkatesan (Champaign, Illinois) |
| ABSTRACT | Provided herein are methods and devices for characterizing a biomolecule parameter by a nanopore-containing membrane, and also methods for making devices that can be used in the methods and devices provided herein. The nanopore membrane is a multilayer stack of conducting layers and dielectric layers, wherein an embedded conducting layer or conducting layer gates provides well-controlled and measurable electric fields in and around the nanopore through which the biomolecule translocates. In an aspect, the conducting layer is graphene. |
| FILED | Thursday, July 26, 2012 |
| APPL NO | 14/234590 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 2522/101 (20130101) C12Q 2537/164 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) G01N 27/44791 (20130101) Original (OR) Class G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175219 | Pratx et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Guillem Pratx (Mountain View, California); Silvan Tuerkcan (Los Altos, California) |
| ABSTRACT | A method of sensing radionuclides in cells is provided that includes exposing a cell of interest to a radiolabeled molecule, encapsulating the cell of interest with a chemical sensor in an encapsulant to hold the cell of interest and the chemical sensor in proximity, where the radiolabeled molecule decays to emit an energetic particle, and detecting a fluorescence or optical absorption signal in the chemical sensor induced by the radio molecule decay, using an illumination source and a detector, where single-cell analysis with the radiolabeled molecule is performed. |
| FILED | Thursday, June 18, 2015 |
| APPL NO | 14/743382 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175237 | Francklyn et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (Burlington, Vermont) |
| ASSIGNEE(S) | University of Vermont and State Agricultural College (Burlington, Vermont) |
| INVENTOR(S) | Christopher Francklyn (Burlington, Vermont); Karen M. Lounsbury (Essex Junction, Vermont); Tamara Williams (South Burlington, Vermont) |
| ABSTRACT | The invention includes, in part, methods and compounds for diagnosing diseases and conditions characterized by altered threonyl-tRNA synthetase (TARS) activity, which include, but are not limited to diseases and conditions in which angiogenesis is altered. In some embodiments of the invention, a level of a TARS molecule is determined and compared to a control level of TARS to assess onset, progression, and/or regression of a disease or condition associated with altered TARS activity. |
| FILED | Wednesday, July 24, 2013 |
| APPL NO | 14/416347 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/25 (20130101) C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 33/57496 (20130101) G01N 2333/9015 (20130101) G01N 2800/52 (20130101) G01N 2800/7014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175238 | Lin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Chen-Yong Lin (Falls Church, Virginia); Michael D. Johnson (Rockville, Maryland); Feng-Pai Chou (Kaohsiung, Taiwan) |
| ABSTRACT | The present invention relates to methods of determining the presence or absence of abnormal lymphoid cells or abnormal myeloid cells in a cell sample, with the methods comprising subjecting the cell sample to conditions that will activate any inactive matriptase present in the cell sample and measuring the levels of activated matriptase in the cell sample. Once measured, these levels can then be compared to control levels of active matriptase to determine if the cell sample has elevated levels of activated matriptase over control levels of active matriptase. An elevation in the levels of activated matriptase in the cell sample is indicative that the cell sample contains abnormal lymphoid cells or abnormal myeloid cells. |
| FILED | Wednesday, May 13, 2015 |
| APPL NO | 14/710949 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 33/57426 (20130101) G01N 2333/96433 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175243 | Watnick |
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| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Randolph S. Watnick (Newton, Massachusetts) |
| ABSTRACT | Provided herein are methods for identifying a subject with cancer for treatment with a Psap peptides. The subject is identified based on a level of CD36. Also provided herein are compositions and methods for treatment of a subject with cancer based on a level of CD36. |
| FILED | Wednesday, August 23, 2017 |
| APPL NO | 15/684639 |
| ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/18 (20130101) A61K 38/1709 (20130101) A61K 47/6811 (20170801) Peptides C07K 5/12 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) Original (OR) Class G01N 2333/70596 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175248 | Mitra |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (Saint Louis, Missouri) |
| ASSIGNEE(S) | Washington University (Saint Louis, Missouri) |
| INVENTOR(S) | Robi D. Mitra (Fenton, Missouri) |
| ABSTRACT | Methods are disclosed for identifying one or more proteins or polypeptides comprised by a sample. The methods comprise determining binding of each polypeptide with respect to each binding pool of a plurality of binding pools, wherein each binding pool comprises one or more probes which bind a structure comprised by a protein or polypeptide. In some aspects, polypeptides can be denatured and separated into individual polypeptide strands and immobilized on a solid support prior to determining binding of the binding pools. A protein, polypeptide or polypeptide strand can be identified by searching, in at least one database, for a protein or polypeptide sequence comprising binding pool targets either identical to or most similar to the binding pool targets comprised by the protein, polypeptide or polypeptide strand to be identified. Kits for identifying proteins, polypeptides and polypeptide strands are also disclosed. |
| FILED | Monday, January 29, 2018 |
| APPL NO | 15/881931 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/6845 (20130101) Original (OR) Class G01N 33/54306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175255 | Komissarov et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Andrey A. Komissarov (Lindale, Texas); Galina Florova (Beaverton, Oregon); Steven Idell (Tyler, Texas) |
| ABSTRACT | An assay that informs precision-based intrapleural fibrinolytic therapy (IPFT) is disclosed. Provided is a simple assay based on measurement of the Fibrinolytic Potential (FP)—total fibrinolytic activity in pleural fluid when plasminogen activator inhibitors (PAIs) are neutralized and endogenous plasminogen (PLG) is activated. The assay is used to determine FP in baseline pleural fluids of patients undergoing IPFT with agents such as tPA or scuPA to determine the dose and dose intervals for the particular patient. Pleural fluids are also collected after IPFT to confirm that intrapleural fibrinolysis is inhibited and endogenous PLG accumulates in the pleural fluid. Inhibition of intrapleural fibrinolysis in combination with its increase after supplementation of pleural fluid with a plasminogen activator indicates whether or not the subject should be treated with more or higher doses of an IPFT drug. |
| FILED | Thursday, March 31, 2016 |
| APPL NO | 15/086623 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/86 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175319 | Truong et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Trong-Kha Truong (Durham, North Carolina); Allen W. Song (Chapel Hill, North Carolina) |
| ABSTRACT | In vivo methods of non-invasively imaging neuro-electro-magnetic oscillations (NEMO) are carried out by electronically transmitting a pulse sequence to a subject. The pulse sequence has a first excitation pulse, typically applied along an x-axis, followed by a spin-lock pulse applied along a different axis, typically a y-axis, and having a defined frequency, followed by a second RF excitation pulse. Then MR image signal of neuroelectric activity associated with evoked and/or spontaneous neuroelectric oscillations is obtained after the second RF excitation pulse and a neuroactivity (i.e., brain activation) map based on the obtained MR image signal is generated, the neuroactivity map having high temporal and spatial accuracy of the neuroelectric activity. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 15/582157 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/54 (20130101) G01R 33/4806 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175325 | Kim et al. |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Sungheon Gene Kim (Millburn, New Jersey); Jin Zhang (Union City, New Jersey) |
| ABSTRACT | In another exemplary embodiment of the present disclosure is an exemplary system, method and computer-accessible for determining a characteristic(s) of a tissue(s), that can include, for example, receiving magnetic resonance imaging information regarding the tissue(s) including a time-intensity curve(s) of the tissue(s) based on a contrast agent(s) concentration, actively encoding a part of the time-intensity curve(s) with a magnetic resonance relaxation property(s) of the tissue(s) by varying a magnetic resonance imaging scan parameter(s) to generate encoded data during magnetic resonance data acquisition, and determining the tissue characteristic(s) based on the encoded data. |
| FILED | Monday, April 27, 2015 |
| APPL NO | 14/696951 |
| ART UNIT | 3768 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/24 (20130101) G01R 33/243 (20130101) G01R 33/246 (20130101) G01R 33/561 (20130101) G01R 33/5601 (20130101) Original (OR) Class G01R 33/5659 (20130101) G01R 33/56366 (20130101) G01R 33/56563 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175326 | Kobayashi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Naoharu Kobayashi (Minneapolis, Minnesota); Michael Garwood (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Naoharu Kobayashi (Minneapolis, Minnesota); Michael Garwood (Minneapolis, Minnesota) |
| ABSTRACT | Systems and methods for pointwise encoding time reduction with radial acquisition (“PETRA”) magnetic resonance imaging (“MRI”) using a gradient modulation scheme to enable higher readout bandwidth while keeping the missing samples of the central region of k-space small are provided. This acquisition scheme allows independent selection of the excitation and readout bandwidths, which allows a higher readout bandwidth while keeping the required number of missing central k-space samples low. This flexibility in selecting the excitation and readout bandwidth settings can mitigate the peak radio frequency power and specific absorption rate limitations on flip angle in traditional PETRA imaging schemes. |
| FILED | Friday, May 13, 2016 |
| APPL NO | 15/153930 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/561 (20130101) Original (OR) Class G01R 33/4816 (20130101) G01R 33/4818 (20130101) G01R 33/4824 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175328 | Hoge et al. |
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| FUNDED BY |
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| APPLICANT(S) | BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL (Boston, Massachusetts) |
| INVENTOR(S) | William Scott Hoge (Watertown, Massachusetts); Jonathan R Polimeni (Cambridge, Massachusetts); Kawin Setsompop (Charlestown, Massachusetts) |
| ABSTRACT | Systems and methods for combined ghost artifact correction and parallel imaging reconstruction of simultaneous multislice (“SMS”) magnetic resonance imaging (“MRI”) data are provided. Dual-polarity training data are used to generate ghost-free slice data, which are used as target data in a reconstruction kernel training process. The training data are used as source data in the reconstruction kernel training. As a result, reconstruction kernels are computed, which can be used to reconstruct images from SMS data in which slice-specific ghosting artifacts are removed. |
| FILED | Monday, August 08, 2016 |
| APPL NO | 15/231267 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/561 (20130101) G01R 33/565 (20130101) G01R 33/4835 (20130101) G01R 33/5611 (20130101) Original (OR) Class G01R 33/5616 (20130101) G01R 33/56554 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176294 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Xiao Yang (Cambridge, Massachusetts); Chang Liu (Cambridge, Massachusetts); Michael C. Zody (Cambridge, Massachusetts); John D. Pfeifer (St. Louis, Michigan) |
| ABSTRACT | Embodiments of the present disclosure present bioinformatic systems, methods, for allelic HLA typing (as well as and computer readable media having instructions for performing methods of HLA typing) using, for example, Illumina exome-sequencing data (e.g., 101 basepair, paired-end reads). |
| FILED | Wednesday, March 12, 2014 |
| APPL NO | 14/772347 |
| ART UNIT | 2896 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 19/18 (20130101) Original (OR) Class G06F 19/22 (20130101) G06F 19/28 (20130101) Computer Systems Based on Specific Computational Models G06N 3/12 (20130101) G06N 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176408 | Paik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David S. Paik (Half Moon Bay, California); Andrew J. Buckler (Wenham, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts) |
| ASSIGNEE(S) | Elucid Bioimaging Inc. (Wenham, Massachusetts) |
| INVENTOR(S) | David S. Paik (Half Moon Bay, California); Andrew J. Buckler (Wenham, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Friday, December 04, 2015 |
| APPL NO | 14/959732 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00147 (20130101) G06K 9/6296 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10172532 | Ni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Kang-Yu Ni (Calabasas, California); James Benvenuto (Beverly Hills, California) |
| ABSTRACT | Described is system for feature transformation of neural activity using sparse and low-rank (SLR) decomposition. A set of neural activity signals associated with different stimuli are obtained, and a neural feature is extracted or each stimuli from the set of neural activity signals using SLR decomposition. The neural feature is then used to generate a classification of the stimuli. The neural activity signals may include functional magnetic resonance imaging (fMRI) signals, fMRI blood-oxygen-level dependent (BOLD) signals, electroencephalography (EEG) signals, functional near-infrared spectroscopy (fNIRS) signals, or magnetoencephalography (MEG) signals. The system according to the principles of the present invention will he an important component of any neural activity based classification system. |
| FILED | Thursday, February 19, 2015 |
| APPL NO | 14/626915 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0075 (20130101) A61B 5/0484 (20130101) A61B 5/04009 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/7271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172930 | Vedvick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TAKEDA VACCINES, INC. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | TAKEDA VACCINES, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Thomas S. Vedvick (Cambridge, Massachusetts); Bryan Steadman (Cambridge, Massachusetts); Charles Richardson (Cambridge, Massachusetts); Thomas R. Foubert (Cambridge, Massachusetts); Charles R. Petrie (Cambridge, Massachusetts) |
| ABSTRACT | Methods for purifying human Calciviruses are disclosed, including Noroviruses and Sapoviruses. |
| FILED | Monday, May 02, 2016 |
| APPL NO | 15/144265 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class Peptides C07K 1/18 (20130101) C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/16023 (20130101) C12N 2770/16034 (20130101) C12N 2770/16051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173262 | Helvajian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Henry Helvajian (Pasadena, California); Anthony J. Manzo (Palmdale, California) |
| ABSTRACT | Under one aspect, a method of processing a material includes heating a region of the material with a first energy source; exciting an acoustic wave in the material; and transmitting the acoustic wave through the heated region, the heated region changing at least one property of the acoustic wave. The method also can include detecting the change in at least one property of the acoustic wave; characterizing a temperature of the material in the heated region based on the detected change in at least one property of the acoustic wave; and comparing the characterized temperature of the material in the heated region to a threshold. The method further can include, based on the characterized temperature of the material in the heated region being less than the threshold or being above the threshold for an insufficient amount of time, modifying a property of the heated region with a second energy source. |
| FILED | Thursday, February 04, 2016 |
| APPL NO | 15/016042 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) Original (OR) Class B22F 3/1055 (20130101) B22F 2003/1057 (20130101) B22F 2203/03 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/02 (20141201) B33Y 80/00 (20141201) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/24 (20130101) Electric Digital Data Processing G06F 17/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173264 | Propheter-Hinckley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Tracy A. Propheter-Hinckley (Manchester, Connecticut); Brandon S. Donnell (Hartford, Connecticut) |
| ABSTRACT | A method includes (a) depositing a layer of a powder material on a work stage, the layer having a thickness, (b) solidifying a portion of the layer based upon data that defines an insert with a body that is shaped to fit into a cavity in a gas turbine engine component, and (c) lowering the work stage by the thickness. Steps (a)-(c) can then be repeated until the insert is complete. The insert can then be removed from the work stage. An insert formed by the above process is also disclosed. |
| FILED | Tuesday, March 11, 2014 |
| APPL NO | 14/774882 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 5/04 (20130101) B22F 5/009 (20130101) Original (OR) Class B22F 2003/1056 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 80/00 (20141201) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) F01D 5/188 (20130101) F01D 5/189 (20130101) F01D 9/041 (20130101) F01D 9/065 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/22 (20130101) F05D 2230/50 (20130101) F05D 2230/234 (20130101) F05D 2260/20 (20130101) F05D 2260/201 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173759 | Castro-Feliciano |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Esteban Luis Castro-Feliciano (Panama City, Florida) |
| ABSTRACT | A combustion buoyancy control system for a submersible object is provided. The buoyancy control system includes a piston cylinder and a piston defining a combustion chamber. An oxidizer inlet introduces oxidizer into the combustion chamber. A fuel injector and igniter device injects fuel into the combustion chamber so that it mixes with the oxidizer in the combustion chamber and then ignites the mixture of oxidizer and fuel in the combustion chamber to produce combustion. Combustion within the combustion chamber displaces the piston member in a first direction causing an increase in the volume of the combustion chamber which increases the buoyancy of the submersible object. Displacement of the piston member in a second opposite direction causes a decrease in the volume of the combustion chamber which in turn decreases the buoyancy of the submersible object. |
| FILED | Friday, October 20, 2017 |
| APPL NO | 15/789050 |
| ART UNIT | 3617 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/14 (20130101) Original (OR) Class B63G 8/22 (20130101) Internal-combustion Piston Engines; Combustion Engines in General F02B 61/00 (20130101) Controlling Combustion Engines F02D 28/00 (20130101) F02D 29/02 (20130101) F02D 37/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173784 | Stewart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James Stewart (Bloomington, Indiana); Lyndon P. McCoy (Bedford, Indiana); Gerald Miller (Bedford, Indiana) |
| ABSTRACT | Various embodiments of the invention can include a portable power system with multiple power generation modes and mode based adjustable drag configuration. Embodiments of the invention include a system with an adjustable inlet ram air inlet, a ram air powered section (e.g. a ram air powered turbine with an adjustable ram air inlet), a fuel powered section, e.g., jet fuel powered auxiliary power unit, which is used when insufficient ram air is present or a power surge requires augmented power generation, and a generator section selectively coupled with the ram air powered section and the fuel powered section. |
| FILED | Tuesday, April 19, 2016 |
| APPL NO | 15/132300 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/12 (20130101) B64D 41/00 (20130101) B64D 41/007 (20130101) Original (OR) Class B64D 2041/002 (20130101) B64D 2221/00 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/36 (20130101) F02C 7/042 (20130101) Jet-propulsion Plants F02K 7/10 (20130101) F02K 7/16 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/34 (20130101) F05D 2220/50 (20130101) F05D 2220/76 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173792 | Burckel |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | David Bruce Burckel (Albuquerque, New Mexico) |
| ABSTRACT | A metallic waveguide tuned to an infrared region of interest provides spectral and spatial control over emitted/absorbed thermal radiation. The ratio of the depth of the waveguide to the smallest lateral dimension thereof is such that that the lateral dimension provides spectral selectivity and that the waveguide is deep enough for a fixed lateral dimension to establish directionality but is not so deep that it incurs severe ohmic losses. A panel with an array of such waveguides directs thermal radiation from a body in a specific direction and with a spectral response that is the result of the physical dimensions of the individual waveguides that make up the waveguide array and the arrangement of the waveguides in the array. The waveguide axis may be obliquely oriented with respect to the substrate normal so as to impart non-normal directionality to the emitted radiation with respect to the substrate normal surface. |
| FILED | Tuesday, November 24, 2015 |
| APPL NO | 14/950298 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/54 (20130101) B64G 1/58 (20130101) Original (OR) Class Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173934 | Divecha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amarnath P. Divecha (Falls Church, Virginia); Subash Karmarkar (Great Falls, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Amarnath P. Divecha (Falls Church, Virginia); Subash Karmarkar (Great Falls, Virginia) |
| ABSTRACT | A method of producing a novel ceramic foam by treating a commercial ceramic foam with powdered glass in an aqueous/alcohol glass gel and with combined silicon carbide whiskers, where the impregnated foam is dried and sintered to form a porous article. |
| FILED | Wednesday, April 25, 1984 |
| APPL NO | 06/604195 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 41/45 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173945 | Buckner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven Wayne Buckner (St. Louis, Missouri); Paul Jelliss (St. Louis, Missouri); Stephen Chung (Florissant, Missouri); Jacob M Laktas (St. Louis, Missouri); Gregory J Place (St. Louis, Missouri) |
| ASSIGNEE(S) | nanoMetallix LLC (Earth City, Missouri) |
| INVENTOR(S) | Steven Wayne Buckner (St. Louis, Missouri); Paul Jelliss (St. Louis, Missouri); Stephen Chung (Florissant, Missouri); Jacob M Laktas (St. Louis, Missouri); Gregory J Place (St. Louis, Missouri) |
| ABSTRACT | The present invention generally concerns isolated nanoparticles via the decomposition of a ternary metal hydride. More specifically, the present invention harnesses increased energy densities from two distinct nanoparticles isolated by a precise decomposition of LiAlH4. The singular material is air stable and is a nanocomposite of Li3AlH6 nanoparticles, elemental Al nanoparticles, an amount of Ti metal, and a nanoscale organic layer, which we call nMx. The nanocomposite protects and preserves the high energy densities of the core metals isolated from the controlled reaction and makes the nanoparticles safe to handle in air. The final composite is devoid of byproducts or phase transitions that will decrease the energy output of the nanocomposite. The method of the present invention creates a narrow distribution of nanoparticles that have unique burning characteristics useful for many applications. |
| FILED | Tuesday, July 25, 2017 |
| APPL NO | 15/659557 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/0078 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 45/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173984 | Shen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | City of Hope (Duarte, California); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | Binghui Shen (La Verne, California); Judith Campbell (Pasadena, California); Li Zheng (Arcadia, California); Hongzhi Li (Duarte, California); David Horne (Duarte, California); Jun Xie (Duarte, California); Kenneth Karanja (Maple Grove, Minnesota) |
| ABSTRACT | Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2. |
| FILED | Tuesday, January 09, 2018 |
| APPL NO | 15/866268 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 215/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174042 | Whitten et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico); University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | David G. Whitten (Albuquerque, New Mexico); Kirk S. Schanze (Gainesville, Florida); Anand Parthasarathy (Gainesville, Florida); Eunkyung Ji (Ervy le Chatel, France); Motokatsu Ogawa (Sherman Oaks, California); Thomas S. Corbitt (Albuquerque, New Mexico); Dimitri Dascier (Ervy le Chatel, France); Ying Wang (Albuquerque, New Mexico); Linnea K. Ista (Albuquerque, New Mexico); Eric H. Hill (Donostia, Spain) |
| ABSTRACT | The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity. |
| FILED | Thursday, November 10, 2016 |
| APPL NO | 15/348756 |
| ART UNIT | 1671 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 217/14 (20130101) C07C 217/20 (20130101) C07C 309/11 (20130101) C07C 309/24 (20130101) Heterocyclic Compounds C07D 333/16 (20130101) C07D 487/08 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) C08G 61/126 (20130101) C08G 75/00 (20130101) C08G 2261/93 (20130101) C08G 2261/312 (20130101) C08G 2261/3223 (20130101) C08G 2261/3328 (20130101) C08G 2261/3422 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174077 | McKee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Patrick A. McKee (Oklahoma City, Oklahoma); Kenneth W. Jackson (Edmond, Oklahoma); Kyung N. Lee (Oklahoma City, Oklahoma); Victoria J. Christiansen (Oklahoma City, Oklahoma) |
| ABSTRACT | The presently disclosed inventive concept(s) include inhibitors of antiplasmin cleaving enzyme (APCE) and fibroblast activation protein alpha (FAP) which can be used in various therapies related to disorders of fibrin and α2-antiplasmin and abnormal cell proliferation. The presently disclosed inventive concept(s) also include substrates of APCE and FAP, which may be used, for example, in screening methods for identifying such inhibitors. The presently disclosed inventive concept(s) further include, but are not limited to, methods of treating or inhibiting atherosclerosis and thrombus disorders by altering the ratios of types of plasma α2-antiplasmin and to methods of treating conditions involving abnormal cell proliferation such as cancers. |
| FILED | Monday, November 21, 2016 |
| APPL NO | 15/357435 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 5/02 (20130101) C07K 5/021 (20130101) C07K 5/081 (20130101) C07K 5/1019 (20130101) C07K 5/06026 (20130101) Original (OR) Class C07K 7/02 (20130101) C07K 14/8121 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174206 | Matzdorf et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Craig Matzdorf (Hollywood, Maryland); William Nickerson (Ashburn, Virginia) |
| ABSTRACT | This invention relates to sacrificial-metal pigments coated with an effective amount of at least one metal oxide or a combination of metal oxides such as a mixture of chromium and zirconium oxides, and the process for preparing said coated pigments and combination thereof with film-forming binders for coating metal substrates to inhibit corrosion. The coated sacrificial-metal pigments are electrically active to prevent corrosion of metal substrates that are more cathodic (electropositive) than the metal oxide coated metal pigments. |
| FILED | Tuesday, November 24, 2015 |
| APPL NO | 14/950835 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/40 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/62 (20130101) C09C 1/642 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/00 (20130101) C09D 5/08 (20130101) Original (OR) Class C09D 5/10 (20130101) C09D 5/082 (20130101) C09D 7/70 (20180101) Alloys C22C 21/00 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 11/00 (20130101) C23F 11/08 (20130101) C23F 11/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174243 | Greytak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andrew B. Greytak (Columbia, South Carolina); Wenhao Liu (Somerville, Massachusetts); Peter M. Allen (Cambridge, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts); Daniel G. Nocera (Winchester, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Andrew B. Greytak (Columbia, South Carolina); Wenhao Liu (Somerville, Massachusetts); Peter M. Allen (Cambridge, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts); Daniel G. Nocera (Winchester, Massachusetts) |
| ABSTRACT | A semiconductor nanocrystal can have a photoluminescent quantum yield of at least 90%, at least 95%, or at least 98%. The nanocrystal can be made by sequentially contacting a nanocrystal core with an M-containing compound and an X donor, where at least one of the M-containing compound and the X donor is substoichiometric with respect to forming a monolayer on the nanocrystal core. |
| FILED | Tuesday, August 24, 2010 |
| APPL NO | 12/862195 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/584 (20130101) Original (OR) Class C09K 11/883 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174619 | Uskert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Richard C. Uskert (Timonium, Maryland); David J. Thomas (Brownsburg, Indiana); Wayne S. Steffier (Huntington Beach, California); Robert J. Shinavski (Mission Viejo, California); Adam L. Chamberlain (Mooresville, Indiana) |
| ABSTRACT | A gas turbine engine composite vane assembly and method for making same are disclosed. The method includes providing at least two gas turbine engine airfoil composite preform components. The airfoil composite preform components are interlocked with a first locking component so that mating faces of the airfoil composite preform components face each other. A filler material is inserted between the mating surfaces of the airfoil composite preform components. |
| FILED | Monday, December 23, 2013 |
| APPL NO | 14/138725 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) Original (OR) Class F01D 5/282 (20130101) F01D 9/044 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/64 (20130101) F05D 2260/36 (20130101) F05D 2300/6012 (20130101) F05D 2300/6033 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49229 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174629 | Valva et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmingtom, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Christopher M. Valva (Manchester, Connecticut); Todd A. Davis (Tolland, Connecticut); Joseph D. Walker (West Hartford, Connecticut) |
| ABSTRACT | A sealing assembly for a bearing compartment of a gas turbine engine includes a shaft and a seal plate mounted to the shaft. The shaft is configured to rotate about a longitudinal axis of the gas turbine engine. The seal plate includes an annular body, scoop, sealing surface, plurality of teeth, and channel. The scoop is connected to and extends radially from the annular body. The scoop defines a lip and an annulus surrounding the shaft and is disposed on a first axial end of the annular body. The sealing surface is disposed on a second axial end of the annular body opposite from the scoop. The plurality of teeth are disposed into and along an outer perimeter of a portion of the annular body. The channel extends through a portion of the annular body and is fluidly connected to the scoop and to the sealing surface. |
| FILED | Monday, September 11, 2017 |
| APPL NO | 15/700922 |
| ART UNIT | 3656 — Material and Article Handling |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/003 (20130101) Original (OR) Class F01D 25/16 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/50 (20130101) F05D 2240/55 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 33/667 (20130101) F16C 37/00 (20130101) F16C 2360/23 (20130101) Pistons; Cylinders; Sealings F16J 15/3404 (20130101) Lubricating F16N 2210/12 (20130101) F16N 2210/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175034 | Hardt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Lee R. Hardt (Ridgecrest, California); Donald L. Burnett (Spearfish, South Dakota); Josiah S. Garfield (Ridgecrest, California); Robert A. Koontz (Anchorage, Alaska) |
| ABSTRACT | Embodiments of the invention are directed to enhancing insensitive munitions performance. Some embodiments of the invention employ an outgassing pad having unique geometrical configurations and positioning. Other embodiments rely on using thermally-releasable components to foster billet expulsion. Additional embodiments combine both aspects into an entire cook-off mitigation system. |
| FILED | Wednesday, March 28, 2018 |
| APPL NO | 15/938598 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/20 (20130101) F42B 12/22 (20130101) F42B 12/207 (20130101) Original (OR) Class F42B 39/14 (20130101) F42B 39/20 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 19/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175047 | Sanders et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Glen A. Sanders (Scottsdale, Arizona); Lee K. Strandjord (Tonka Bay, Minnesota); Austin Taranta (Scottsdale, Arizona) |
| ABSTRACT | Systems and methods for dynamic bias offset operation in RFOGs are provided. In certain embodiments, an RFOG system includes a fiber optic resonator; laser sources that launch first and second optical beams into the fiber optic resonator in opposite directions; a first servo loop configured to lock the first optical beam to a resonance frequency, the first servo loop including a modulator that modulates the first optical beam at a first resonant tracking frequency; a second servo loop configured to lock the second optical beam frequency, on average, to a resonance frequency, the second servo loop including a modulator that modulates the second optical beam at a second resonant tracking frequency, wherein the second optical beam is further modulated by a modulation frequency; and a filter configured to attenuate signals that result from the interference of the first and second optical beams. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/591950 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/727 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/40 (20130101) H01S 5/0687 (20130101) H01S 5/1071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175102 | Markov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Systems and Technologies, Inc. (Irvine, California) |
| ASSIGNEE(S) | ADVANCED SYSTEMS and TECHNOLOGIES, INC. (Irvine, California) |
| INVENTOR(S) | Vladimir Markov (Irvine, California); Anatoliy Khizhnyak (Irvine, California) |
| ABSTRACT | A system for forming virtual beacons usable in wavefront sensing includes a first lens configured to receive light from a target and to output an image towards an input plane. The system also includes a selector positioned at the input plane. The selector includes a transparent portion that allows a portion of the image output by the first lens to pass through the selector to form a virtual beacon. The selector also includes a translucent portion to prevent another portion of the image output by the first lens from passing through the selector. |
| FILED | Thursday, May 26, 2016 |
| APPL NO | 15/166101 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/0411 (20130101) G01J 1/0437 (20130101) G01J 1/4228 (20130101) Original (OR) Class G01J 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175240 | Mouchantat |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Jennifer Richer Mouchantat (Denver, Colorado) |
| ABSTRACT | The present invention provides a method for determining a treatment procedure for breast cancer, a method of predicting a likelihood of success in treating breast cancer, and a method for selecting an endocrine therapy agent for treating breast cancer. In particular, methods of the present invention rely on the amount of androgen receptor (AR) and estrogen receptor (ER) in a tissue sample. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 14/423133 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/743 (20130101) G01N 33/57415 (20130101) Original (OR) Class G01N 2333/723 (20130101) G01N 2500/02 (20130101) G01N 2500/10 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175249 | Lavinder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Jason Lavinder (Round Rock, Texas); Daniel Boutz (Austin, Texas); Yariv Wine (Austin, Texas); Edward M. Marcotte (Austin, Texas); George Georgiou (Austin, Texas) |
| ABSTRACT | Methods and compositions for identification of candidate antigen-specific variable regions as well as generation of antibodies or antigen-binding fragments that could have desired antigen specificity are provided. For example, in certain aspects, methods for determining amino acid sequences of serum antibody CDR3 and abundancy levels are described. In some aspects, methods for determining nucleic acid sequences of antibody variable region sequences and the frequency thereof in biological samples are provided. Furthermore, the invention provides methods for identification and generation of antibodies or antigen-binding fragments that comprise highly-represented CDR domains. |
| FILED | Friday, September 25, 2015 |
| APPL NO | 14/865302 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/531 (20130101) G01N 33/6848 (20130101) G01N 33/6854 (20130101) G01N 33/6857 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175266 | Siddiqui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jeffrey J. Siddiqui (Sacramento, California); Ajit Sandhu (Yuba City, California); Joe Y. Liu (Roseville, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey J. Siddiqui (Sacramento, California); Ajit Sandhu (Yuba City, California); Joe Y. Liu (Roseville, California) |
| ABSTRACT | A wafer level electrical probe system with multiple wavelength and intensity illumination capability system that enables concurrent reliability studies of illumination stimulation, electrical stimulation, and the interplay of both electrical and illumination stimulation. The probe system includes five sub-systems: a controllable wavelength and intensity illumination input sub-system with two different configurations; a wafer level electrical probe sub-system; an illumination intensity calibration sub-system; an illumination delivery sub-system; and an illumination wavelength calibration sub-system. |
| FILED | Thursday, March 19, 2015 |
| APPL NO | 14/662575 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 1/071 (20130101) Original (OR) Class G01R 31/2656 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175306 | Miesner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John E. Miesner (Fairfax, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John E. Miesner (Fairfax, Virginia) |
| ABSTRACT | An exemplary magnetic flux sensor in accordance with the present invention is characterized by an electrical output that is proportional to the total static and dynamic flux passing normally through a large area. An oscillating electrical current passing down a conducting area produces Lorentz forces, which are transferred to piezoelectric areas. The piezoelectric areas produce electrical voltage at the oscillation frequency whereby amplitude is proportional to the total magnetic flux passing normally through the conducting area. Demodulating the voltage provides an electrical signal with high sensitivity, dynamic range, and noise immunity. |
| FILED | Thursday, December 01, 2016 |
| APPL NO | 15/366330 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/028 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175308 | Berggren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Susan Anne Elizabeth Berggren (San Diego, California); Benjamin J. Taylor (Escondido, California); Anna Leese de Escobar (Encinitas, California) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Susan Anne Elizabeth Berggren (San Diego, California); Benjamin J. Taylor (Escondido, California); Anna Leese de Escobar (Encinitas, California) |
| ABSTRACT | A High Temperature Superconducting (HTS) Superconducting Quantum Interference Device and methods for fabrication can include at least one bi-Superconducting Quantum Interference Device. The bi-SQUID can include an HTS substrate that can be formed with a step edge. A superconducting loop of YBCO can be deposited on the step edge to establish two Josephson Junctions. A superconducting path that bi-sects the superconducting loop path can also be deposited onto the substrate. In some embodiments, the bisecting path can cross the step edge twice, and the bisecting path can be ion milled at one of the crossing points to round the bisecting path and thereby remove the fourth Josephson Junction at the other crossing point. In still other embodiments, the bisecting path can be completely on the upper shelf (or the lower shelf), and the bisecting path can be ion damaged, ion damaged, or particle damaged, to establish the third Josephson Junction. |
| FILED | Wednesday, August 22, 2018 |
| APPL NO | 16/109336 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/035 (20130101) G01R 33/0354 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175345 | Rhee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Voxtel, inc. (Beaverton, Oregon) |
| ASSIGNEE(S) | Voxtel, Inc. (Beaverton, Oregon) |
| INVENTOR(S) | Jehyuk Rhee (King City, Oregon); Adam Lee (Portland, Oregon); George Williams (Portland, Oregon) |
| ABSTRACT | An imaging device is disclosed, the device comprising a pixelated array of semiconductor detector elements, in which each detecting element is electrically connected to an integrated circuit, the integrated circuit comprising a passive signal path and an active signal path. The active path provides consecutive frame imaging and the active path detects the location of transient events. The device further comprising a readout decoder block, the readout decoder block controlling operation of the passive paths. Additionally the device comprises of an address arbitration control block, the address arbitration control block controlling operation of the active paths, wherein the address arbitration control block readout of the active paths is independent of readout of the passive paths. |
| FILED | Thursday, January 29, 2015 |
| APPL NO | 14/609098 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4863 (20130101) G01S 7/4865 (20130101) Original (OR) Class G01S 17/10 (20130101) G01S 17/023 (20130101) G01S 17/89 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175349 | Ternovskiy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Igor Ternovskiy (Xenia, Ohio); Tony Kim (Xenia, Ohio) |
| ABSTRACT | A multi-modal omnidirectional sensor includes an ovaloid aperture having a plurality of tapered square prismatic cells formed from a plurality of partition walls. A focal ovaloid is concentric with the ovaloid aperture, and the focal ovaloid has an outer surface dimension that coincides with a focal distance of the ovaloid aperture. A multi-mode sensor array is disposed on the focal ovaloid, and is configured to receive an optical signal and a radio frequency (RF) signal. One of the plurality of partition walls comprises a non-metalic dielectric mirror. One of the plurality of partition walls is configured to be reflective to a band of desired wavelengths of the optical signal while being transparent to the RF signal. |
| FILED | Friday, November 13, 2015 |
| APPL NO | 14/940193 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/89 (20130101) G01S 13/865 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175358 | Struckhoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ELBIT SYSTEMS OF AMERICA, LLC (Fort Worth, Texas) |
| ASSIGNEE(S) | Elbit Systems of America, LLC (Fort Worth, Texas) |
| INVENTOR(S) | Andrew Struckhoff (Fort Worth, Texas); Tom Hardy (Fort Worth, Texas); Jason R. Lane (Fort Worth, Texas); James Sarette (Fort Worth, Texas); Darius Coakley (Fort Worth, Texas) |
| ABSTRACT | An apparatus for target location is disclosed. The apparatus includes a housing, which includes a range sensor to generate range data, an image sensor to generate image data, an inertial sensor to generate inertia data, and a processor. The processor is configured to receive the image data from the image sensor and determine a first orientation of the housing and receive the inertia data from the inertial sensor and modify the first orientation based on the inertia data to produce a modified orientation of the housing. |
| FILED | Tuesday, August 04, 2015 |
| APPL NO | 14/817688 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 17/34 (20130101) G01C 21/02 (20130101) G01C 21/005 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/7861 (20130101) G01S 3/7867 (20130101) G01S 17/08 (20130101) G01S 17/023 (20130101) G01S 17/46 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175476 | Goldberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Bennett B. Goldberg (Newton, Massachusetts); Thomas Bifano (Mansfield, Massachusetts); Selim M. Unlu (Jamaica Plain, Massachusetts); Euan Ramsay (Dublin, California); Fatih Hakan Koklu (Sunnyvale, California); Jerome Mertz (Cambridge, Massachusetts); Yang Lu (Boston, Massachusetts); Abdulkadir Yurt (Brighton, Massachusetts); Christopher Stockbridge (Natick, Massachusetts) |
| ABSTRACT | A system and method for correction of aberrations in a solid immersion microscopy system using a deformable mirror. A solid immersion lens is provided having a surface configured to make optical contact with a nearly planar surface of a substrate, an object to be imaged disposed on the opposite side of the substrate. A convex surface of the solid immersion lens faces an objective lens. A deformable mirror assembly, including a plurality of individually controllable actuators, receives light transmitted from the object. A control system controls in communication with the deformable mirror assembly provides individual actuation of each of the actuators of the deformable mirror to compensate or counteract the effects of aberrations. |
| FILED | Monday, July 15, 2013 |
| APPL NO | 14/414919 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/04 (20130101) G02B 21/06 (20130101) G02B 21/0016 (20130101) G02B 21/33 (20130101) G02B 21/0048 (20130101) G02B 21/0056 (20130101) G02B 26/0825 (20130101) G02B 26/0841 (20130101) G02B 27/0068 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175491 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Magic Leap, Inc. (Plantation, Florida) |
| ASSIGNEE(S) | Magic Leap, Inc. (Plantation, Florida) |
| INVENTOR(S) | Chunyu Gao (Tucson, Arizona); Yuxiang Lin (Tucson, Arizona); Hong Hua (Tucson, Arizona) |
| ABSTRACT | The present invention comprises a compact optical see-through head-mounted display capable of combining, a see-through image path with a virtual image path such that the opaqueness of the see-through image path can be modulated and the virtual image occludes parts of the see-through image and vice versa. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/977593 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 13/06 (20130101) G02B 25/001 (20130101) G02B 27/144 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 27/283 (20130101) G02B 27/1066 (20130101) G02B 2027/015 (20130101) G02B 2027/0118 (20130101) G02B 2027/0145 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 37/02 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Pictorial Communication, e.g Television H04N 5/2258 (20130101) H04N 5/23238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176063 | Alvarez-Icaza Rivera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Rodrigo Alvarez-Icaza Rivera (San Jose, California); John V. Arthur (Mountain View, California); John E. Barth, Jr. (Williston, Vermont); Andrew S. Cassidy (San Jose, California); Subramanian Iyer (Mount Kisco, New York); Paul A. Merolla (Palo Alto, California); Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | Embodiments of the invention relate to faulty recovery mechanisms for a three-dimensional (3-D) network on a processor array. One embodiment comprises a multidimensional switch network for a processor array. The switch network comprises multiple switches for routing packets between multiple core circuits of the processor array. The switches are organized into multiple planes. The switch network further comprises a redundant plane including multiple redundant switches. Multiple data paths interconnect the switches. The redundant plane is used to facilitate full operation of the processor array in the event of one or more component failures. |
| FILED | Thursday, April 21, 2016 |
| APPL NO | 15/135444 |
| ART UNIT | 2463 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 11/165 (20130101) G06F 11/2033 (20130101) Original (OR) Class G06F 15/803 (20130101) G06F 2201/845 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0654 (20130101) H04L 49/101 (20130101) H04L 49/552 (20130101) H04L 49/557 (20130101) H04L 49/1523 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176260 | Mahapatra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Amogh Mahapatra (Santa Clara, California); Nisheeth Srivastava (Avon, Connecticut); Jaideep Srivastava (Plymouth, Minnesota) |
| ABSTRACT | A computing device may determine, based at least in part on one or more semantic exemplars associated with a digital object, a level of incongruity for the digital object, and output an indication of the level of incongruity for the digital object. For instance, a system may provide a web application that can support hedonic web surfing. By modeling Internet users as active information foragers instead of random surfers, a system may obtain quantitative measures of digital objects that users may find psychologically stimulating. The system may utilize a quantitative measure of the conceptual incongruity of digital objects that may predict how interesting users will find an object. |
| FILED | Tuesday, February 10, 2015 |
| APPL NO | 14/618838 |
| ART UNIT | 2168 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 17/2785 (20130101) G06F 17/3053 (20130101) G06F 17/3069 (20130101) G06F 17/30315 (20130101) G06F 17/30321 (20130101) G06F 17/30663 (20130101) G06F 17/30684 (20130101) G06F 17/30731 (20130101) G06F 17/30864 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176933 | Irazoqui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Pedro P. Irazoqui (Lafayette, Indiana); Oren Gall (Lafayette, Indiana); Chuizhou Meng (Troy, New York); Jimin Maeng (West Lafayette, Indiana) |
| ABSTRACT | An energy storage device includes first and second electrodes and a solid state electrolyte. The first electrode includes carbon nanotubes, a conductive polymer, and a metallization on said carbon nanotubes. The second electrode similarly includes carbon nanotubes, a conductive polymer, and a metallization on said carbon nanotubes. The solid state electrolyte is disposed at least in part between the first electrode and the second electrode. In at least some embodiments, the conductive polymer of the first electrode includes polyaniline, and the metallization of the first electrode is a gold metallization. |
| FILED | Friday, October 25, 2013 |
| APPL NO | 14/438620 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/36 (20130101) Original (OR) Class H01G 11/48 (20130101) H01G 11/56 (20130101) H01G 11/84 (20130101) H01G 11/86 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 50/00 (20160201) H02J 50/27 (20160201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177116 | Andry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Paul S. Andry (Yorktown Heights, New York); Mark D. Schultz (Ossining, New York); Cornelia K. Tsang (Mohegan Lake, New York) |
| ABSTRACT | An electrical device that includes at least two active wafers having at least one through silicon via, and at least one unitary electrical communication and spacer structure present between a set of adjacently stacked active wafers of the at least two active wafers. The unitary electrical communication and spacer structure including an electrically conductive material core providing electrical communication to the at least one through silicon via structure in the set of adjacently stacked active wafers and a substrate material outer layer. The at least one unitary electrical communication and spacer structure being separate from and engaged to the adjacently stacked active wafers, wherein coolant passages are defined between surfaces of the adjacently stacked active wafers and the at least one unitary electrical communication and spacer structure. |
| FILED | Friday, January 30, 2015 |
| APPL NO | 14/610416 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/473 (20130101) H01L 23/481 (20130101) H01L 24/16 (20130101) H01L 24/32 (20130101) H01L 24/73 (20130101) H01L 24/81 (20130101) H01L 24/94 (20130101) H01L 25/50 (20130101) H01L 25/0657 (20130101) Original (OR) Class H01L 2224/81 (20130101) H01L 2224/94 (20130101) H01L 2224/94 (20130101) H01L 2224/131 (20130101) H01L 2224/131 (20130101) H01L 2224/291 (20130101) H01L 2224/291 (20130101) H01L 2224/16146 (20130101) H01L 2224/32225 (20130101) H01L 2224/73203 (20130101) H01L 2224/81005 (20130101) H01L 2225/06513 (20130101) H01L 2225/06541 (20130101) H01L 2225/06589 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2924/014 (20130101) H01L 2924/014 (20130101) H01L 2924/1305 (20130101) H01L 2924/1431 (20130101) H01L 2924/1434 (20130101) H01L 2924/1435 (20130101) H01L 2924/1436 (20130101) H01L 2924/1438 (20130101) H01L 2924/10252 (20130101) H01L 2924/10253 (20130101) H01L 2924/10271 (20130101) H01L 2924/10272 (20130101) H01L 2924/10329 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177181 | Grzesik |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael J. Grzesik (Lompoc, California) |
| ABSTRACT | There is provided a photodiode array including a semiconducting substrate and a plurality of photodiodes that are disposed at a surface of the substrate. Each photodiode is laterally spaced apart from neighboring photodiodes by a lateral substrate surface region. An optical interface surface of the substrate is arranged for accepting external input radiation. A plurality of electrically conducting fuses are disposed on the substrate surface. Each fuse is connected to a photodiode in the plurality of photodiodes. Each fuse is disposed at a lateral substrate surface region that is spaced apart from neighboring photodiodes in the plurality of photodiodes. |
| FILED | Wednesday, May 27, 2015 |
| APPL NO | 14/722702 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 85/25 (20130101) H01H 85/046 (20130101) H01H 2085/0275 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1443 (20130101) H01L 27/1446 (20130101) Original (OR) Class H01L 31/102 (20130101) H01L 31/02005 (20130101) H01L 31/02027 (20130101) H01L 2924/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177298 | Taylor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Benjamin J. Taylor (Escondido, California); Teresa H. Emery (San Diego, California); Susan Anne Elizabeth Berggren (San Diego, California); Anna M. Leese de Escobar (Encinitas, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin J. Taylor (Escondido, California); Teresa H. Emery (San Diego, California); Susan Anne Elizabeth Berggren (San Diego, California); Anna M. Leese de Escobar (Encinitas, California) |
| ABSTRACT | A Josephson junction device and methods for manufacture can include an untwinned YBa2Cu3Ox nanowire having crystallographic a- and b-axes. The nanowire can be established from YBa2Cu3Ox film (6.0≤x≤7.0) using a photolithography process, followed by an ion milling process, to yield the YBa2Cu3Ox nanowire. The crystallographic b-axis of the nanowire can be parallel to the long dimension of the nanowire. First and second gate structures can be placed on opposite sides of the nanowire across from each other, to establish first and second microgaps. A gate voltage can be selectively applied across the first and said second gate structures, which can further establish a selective electric field across the first and second microgaps. The electric field can be parallel to the nanowire crystallographic a-axis, to selectively cause an at will Josephson junction effect. |
| FILED | Tuesday, September 26, 2017 |
| APPL NO | 15/715273 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 99/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02019 (20130101) H01L 39/223 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177519 | Alam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Khashan F. Alam (Oro Valley, Arizona); James A. Hinsdale (Marana, Arizona); Erik W. Matter (Tucson, Arizona) |
| ABSTRACT | A connector demating tool can include first and second jaws moveable relative to one another. First and second separators can be supported about the first and second jaws. The first and second separators can be configured to engage first and second connector portions of a connector. An actuating mechanism can be operable to actuate at least one of the first and second jaws and the first and second separators. The actuating mechanism can facilitate application of, by the first and second separators, an equal separation force to the first and second connector portions of the connector to demate the connector. |
| FILED | Monday, November 23, 2015 |
| APPL NO | 14/949725 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 27/02 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 43/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177526 | Bochove |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia) |
| INVENTOR(S) | Erik Johannes Bochove (Corrales, New Mexico) |
| ABSTRACT | Light beams from multiple emitters, such as lasers, arranged in two or more arrays are combined by beam-superposition using a dispersive element, such as a diffraction grating, to provide a combined output beam with increased power. Each emitter produces light of a controlled wavelength that is incident upon the diffraction grating at a corresponding selected incidence angle to produce a diffracted wave that propagates in an output direction and forms a component of the combined output beam. First and second arrays are located on opposing sides of the combined output beam and are arranged such that light from all of the emitters overlaps to form the combined output beam. The wavelengths may be controlled by an external resonator, for example. As many as four arrays may be combined using a two-dimensional diffraction grating. |
| FILED | Thursday, November 30, 2017 |
| APPL NO | 15/828122 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/067 (20130101) H01S 3/137 (20130101) H01S 3/0623 (20130101) H01S 3/1305 (20130101) H01S 3/2308 (20130101) Original (OR) Class H01S 3/08009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177742 | Nguyen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Clark T.-C. Nguyen (Oakland, California); Thura Lin Naing (Berkeley, California); Tristan O. Rocheleau (Berkeley, California) |
| ABSTRACT | Active feedback is used with two electrodes of a four-electrode capacitive-gap transduced wine-glass disk resonator to enable boosting of an intrinsic resonator Q and to allow independent control of insertion loss across the two other electrodes. Two such Q-boosted resonators configured as parallel micromechanical filters may achieve a tiny 0.001% bandwidth passband centered around 61 MHz with only 2.7 dB of insertion loss, boosting the intrinsic resonator Q from 57,000, to an active Q of 670,000. The split capacitive coupling electrode design removes amplifier feedback from the signal path, allowing independent control of input-output coupling, Q, and frequency. Controllable resonator Q allows creation of narrow channel-select filters with insertion losses lower than otherwise achievable, and allows maximizing the dynamic range of a communication front-end without the need for a variable gain low noise amplifier. |
| FILED | Monday, November 14, 2016 |
| APPL NO | 15/351047 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/29 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/64 (20130101) H03H 9/465 (20130101) H03H 9/525 (20130101) H03H 9/2426 (20130101) H03H 9/2436 (20130101) H03H 11/0466 (20130101) Original (OR) Class H03H 11/0472 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177768 | Iyengar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Anirudh Srikant Iyengar (Tampa, Florida); Swaroop Ghosh (Tampa, Florida); Deepakreddy Vontela (Tampa, Florida); Ithihasa Reddy Nirmala (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Anirudh Srikant Iyengar (Tampa, Florida); Swaroop Ghosh (Tampa, Florida); Deepakreddy Vontela (Tampa, Florida); Ithihasa Reddy Nirmala (Tampa, Florida) |
| ABSTRACT | Disclosed are various embodiments providing circuitry that includes camouflaged gates that each have multiple switches arranged in a predefined format. A switch at a specific position in one camouflaged gate can have a different threshold voltage than a switch at the specific position in another camouflaged gate. The logical function performed by the camouflaged gate can be based on which of the switches have a low threshold voltage and which of the switches have a high threshold voltage. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/011977 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/079 (20130101) G06F 11/0706 (20130101) G06F 11/0751 (20130101) G06F 11/0793 (20130101) G06F 17/50 (20130101) G06F 21/75 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/57 (20130101) H01L 29/80 (20130101) Pulse Technique H03K 17/302 (20130101) H03K 19/17768 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177949 | Musselman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Randall Lee Musselman (Colorado Springs, Colorado) |
| ABSTRACT | Embodiments of the invention provide advances in liquid-crystal technology for use as tunable phase-delay lines. The amount of phase delay through the liquid crystal is adaptively tuned, in order to coherently combine two signals, regardless of their phase differences. By adaptively adjusting the phase delays in the two signal paths, maximum coherent power combining is ensured. This ability to coherently combine the power of two signals regardless of their initial phase differences can greatly simplify, for example, antenna-diversity techniques used in MIMO applications as well as other applications. |
| FILED | Thursday, August 03, 2017 |
| APPL NO | 15/667661 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/134336 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/097 (20130101) H03L 7/107 (20130101) H03L 7/0812 (20130101) Multiplex Communication H04J 1/065 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/142 (20130101) H04L 27/148 (20130101) H04L 27/227 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10178028 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nytell Software LLC (Wilmington, Delaware) |
| ASSIGNEE(S) | Nytell Software LLC (Wilmington, Delaware) |
| INVENTOR(S) | Kirk Chang (Morganville, New Jersey); Gi Tae Kim (Morristown, New Jersey); John Unger (Bud Lake, New Jersey); John Sucec (Piscataway, New Jersey); Sunil Samtani (East Newark, New Jersey) |
| ABSTRACT | In a secure network where the network characteristics are not known, a call admission control algorithm and a preemption control algorithm based on a destination node informing the source node of the observed carried traffic are used to regulate the amount of traffic that needs to be preempted by the source. The amount of traffic that needs to be preempted is based on the carried traffic measured at the destination node. The traffic to be preempted is based on the priority of the traffic, where the lowest priority traffic is the first to be preempted until the amount of traffic preempted is sufficient to allow the remaining traffic to pass through the network without congestion. |
| FILED | Wednesday, August 10, 2016 |
| APPL NO | 15/233156 |
| ART UNIT | 2479 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/10 (20130101) Original (OR) Class H04L 47/11 (20130101) H04L 47/70 (20130101) H04L 47/245 (20130101) H04L 47/805 (20130101) H04L 47/822 (20130101) H04L 47/2408 (20130101) H04L 47/2433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10178041 | Dinan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | James Dinan (Hudson, Massachusetts); Mario Flajslik (Hudon, Massachusetts); David Keppel (Seattle, Washington); Ulf R. Hanebutte (Gig Harbor, Washington) |
| ABSTRACT | Technologies for aggregation-based message processing include multiple computing nodes in communication over a network. A computing node receives a message from a remote computing node, increments an event counter in response to receiving the message, determines whether an event trigger is satisfied in response to incrementing the counter, and writes a completion event to an event queue if the event trigger is satisfied. An application of the computing node monitors the event queue for the completion event. The application may be executed by a processor core of the computing node, and the other operations may be performed by a host fabric interface of the computing node. The computing node may be a target node and count one-sided messages received from an initiator node, or the computing node may be an initiator node and count acknowledgement messages received from a target node. Other embodiments are described and claimed. |
| FILED | Wednesday, September 23, 2015 |
| APPL NO | 14/862854 |
| ART UNIT | 2454 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/04 (20130101) H04L 43/16 (20130101) H04L 47/10 (20130101) H04L 47/30 (20130101) H04L 47/41 (20130101) H04L 47/62 (20130101) Original (OR) Class Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10178336 | Rizk et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Charbel G. Rizk (Sykesville, Maryland); Philippe O. Pouliquen (Baltimore, Maryland); Andreas G. Andreou (Baltimore, Maryland); Joseph H. Lin (Lowell, Massachusetts) |
| ABSTRACT | A computational sensing array includes an array of sensing elements. In each sensing element, a first signal is generated from a transducer. A second signal is produced by a collection unit in response to receiving the first signal. The second signal may be modified, in a conditioning unit. A sensing element preprocessing unit generates a word representing the value of the modified second signal, and may produce an indication of change of the first signal. A current value of the word may be stored in a state holding element local to the sensing element, and a previous value of the word may be retained in a further state holding element local to the sensing element. |
| FILED | Wednesday, June 28, 2017 |
| APPL NO | 15/635262 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) Pictorial Communication, e.g Television H04N 5/357 (20130101) H04N 5/369 (20130101) H04N 5/374 (20130101) H04N 5/378 (20130101) Original (OR) Class H04N 5/379 (20180801) H04N 5/3651 (20130101) H04N 5/37455 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10178792 | Meinhart |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael A Meinhart (Washington, Indiana) |
| ABSTRACT | A command and control system and related methods are provided including an integrated shipping case/equipment mounting structure, a multi-application information fusion work station, a communication system, an expandable display array, a location determining system, and a data center section with data servers and network hub capability. Embodiments of the system includes design configurations enabling operation with reduced or passive environmental and temperature control capabilities including a compact cooling system usable with a compact layout and close proximity components that provide needed low power consumption cooling capability. Embodiments provide a portable, compact, rapid employable, reduced power consumption and lightweight information command and control capability operable in austere environments. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/954444 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/20 (20130101) G06F 1/182 (20130101) G06F 1/184 (20130101) G06F 1/189 (20130101) G06F 1/1601 (20130101) G06F 8/61 (20130101) G06F 2200/201 (20130101) G06F 2200/1612 (20130101) Secret Communication; Jamming of Communication H04K 3/224 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 5/023 (20130101) H05K 7/16 (20130101) H05K 7/1487 (20130101) Original (OR) Class H05K 7/1498 (20130101) H05K 7/20263 (20130101) H05K 7/20272 (20130101) H05K 7/20772 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10178813 | Boteler et al. |
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| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Lauren M. Boteler (Highland, Maryland); Damian P. Urciuoli (Bowie, Maryland) |
| ABSTRACT | A power module including a plurality of power die layers including power electronic components; a plurality of heat sink components operatively connected to multiple sides of each power electronic component; a plurality of electrically conductive layers contacting the plurality of heat sink components, wherein a power die layer and an electrically conductive layer sequentially alternate to form a stacked structure such that both ends of the stacked structure includes an end electrically conductive layer. A cooling path is integrated with each layer in the stacked structure. A housing unit houses the stacked structure. The power electronic components may include heat-producing electronic devices. The cooling path may accommodate any of a fluid and solid to liquid phase change materials. The fluid comes into direct contact with the power die layers, heat sink components, and electrically conductive layers. |
| FILED | Thursday, January 26, 2017 |
| APPL NO | 15/416495 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/158 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/209 (20130101) H05K 7/2089 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10172933 | Rieder et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Aida E. Rieder (Westbrook, Connecticut); William M. Fischer (Santa Fe, New Mexico); Devendra K. Rai (Old Saybrook, Connecticut) |
| ABSTRACT | Synthetic foot-and-mouth disease virus (FMDV) mosaic polypeptides, and nucleic acid molecules encoding the mosaic polypeptides, are described. The mosaic polypeptides have greater T-cell epitope coverage than naturally occurring FMDV polypeptides, and include common FMDV epitopes, but exclude rare FMDV epitopes. When included as part of an FMDV genome, the mosaic polypeptides permit virus replication and assembly into FMDV particles. The mosaic polypeptide and nucleic acid compositions can be used to elicit immune responses that provide protection against a broad range of serotype A FMDV strains. |
| FILED | Tuesday, October 17, 2017 |
| APPL NO | 15/785875 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/135 (20130101) Original (OR) Class A61K 2039/55566 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/32122 (20130101) C12N 2770/32134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172967 | Norenberg |
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| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Jeffrey P. Norenberg (Albuquerque, New Mexico) |
| ABSTRACT | A subject afflicted with a cancer or precancerous condition is treated by administering an agent that increases expression of somatostatin receptors, and a cytotoxic recognition ligand. In an alternative embodiment, somatostatin analogs, which are radiolabeled are used to treat cancer or precancerous conditions. |
| FILED | Wednesday, February 08, 2017 |
| APPL NO | 15/427355 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7068 (20130101) A61K 31/7068 (20130101) A61K 38/31 (20130101) A61K 38/31 (20130101) A61K 45/06 (20130101) A61K 51/08 (20130101) Original (OR) Class A61K 51/083 (20130101) A61K 51/088 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173169 | Masel |
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| FUNDED BY |
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| APPLICANT(S) | Dioxide Materials, Inc. (Boca Raton, Florida) |
| ASSIGNEE(S) | Dioxide Materials, Inc (Boca Raton, Florida) |
| INVENTOR(S) | Richard I. Masel (Boca Raton, Florida) |
| ABSTRACT | An electrocatalytic device for carbon dioxide conversion includes a cathode with a Catalytically Active Elementa metal in the form of supported or unsupported particles or flakes with an average size between 0.6 nm and 100 nm. The reaction products comprise at least one of CO, HCO−, H2CO, (HCOO)−, HCOOH, CH3OH, CH4, C2H4, CH3CH2OH, CH3COO−, CH3COOH, C2H6, (COOH)2, (COO−)2, and CF3COOH. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/724933 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/326 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0202 (20130101) B01J 31/0275 (20130101) B01J 31/0279 (20130101) B01J 31/0284 (20130101) B01J 31/0285 (20130101) B01J 31/0292 (20130101) B01J 31/0298 (20130101) B01J 2231/625 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 3/04 (20130101) C25B 15/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173792 | Burckel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | David Bruce Burckel (Albuquerque, New Mexico) |
| ABSTRACT | A metallic waveguide tuned to an infrared region of interest provides spectral and spatial control over emitted/absorbed thermal radiation. The ratio of the depth of the waveguide to the smallest lateral dimension thereof is such that that the lateral dimension provides spectral selectivity and that the waveguide is deep enough for a fixed lateral dimension to establish directionality but is not so deep that it incurs severe ohmic losses. A panel with an array of such waveguides directs thermal radiation from a body in a specific direction and with a spectral response that is the result of the physical dimensions of the individual waveguides that make up the waveguide array and the arrangement of the waveguides in the array. The waveguide axis may be obliquely oriented with respect to the substrate normal so as to impart non-normal directionality to the emitted radiation with respect to the substrate normal surface. |
| FILED | Tuesday, November 24, 2015 |
| APPL NO | 14/950298 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/54 (20130101) B64G 1/58 (20130101) Original (OR) Class Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173915 | Rue et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David M. Rue (Chicago, Illinois); V. Walter Kunc (Clarendon Hills, Illinois); John Charles Wagner (Lagrange, Illinois); Chun W. Choi (Chicago, Illinois) |
| ASSIGNEE(S) | GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois) |
| INVENTOR(S) | David M. Rue (Chicago, Illinois); V. Walter Kunc (Clarendon Hills, Illinois); John Charles Wagner (Lagrange, Illinois); Chun W. Choi (Chicago, Illinois) |
| ABSTRACT | A method for removing gaseous inclusions from a viscous liquid in which a viscous liquid stream having gaseous inclusions is introduced into a refining chamber, resulting in a flowing viscous liquid layer. The viscosity of a bottom portion of the viscous liquid layer is reduced in a first refining zone in the refining chamber so as to produce an upwardly mobile reduced viscosity portion of the viscous liquid layer. Heat is introduced into the viscous liquid layer from above the viscous liquid layer in a second refining zone in the refining chamber downstream of the first refining zone, reducing the gaseous inclusions in said viscous liquid layer. Thereafter, the viscous liquid layer having substantially reduced gaseous inclusions is discharged from the refining chamber. |
| FILED | Friday, February 18, 2011 |
| APPL NO | 13/030173 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Separation B01D 19/0042 (20130101) B01D 19/0073 (20130101) Manufacture, Shaping, or Supplementary Processes C03B 5/225 (20130101) Original (OR) Class C03B 5/2356 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174063 | Dinca et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Mircea Dinca (Belmont, Massachusetts); Dennis Sheberla (Watertown, Massachusetts); Lei Sun (Cambridge, Massachusetts); Casey R. Wade (Waltham, Massachusetts); Michael Glenn Campbell (Cambridge, Massachusetts) |
| ABSTRACT | Compositions and methods comprising metal organic frameworks (MOFs) and related uses are generally provided. In some embodiments, a MOF comprises a plurality of metal ions, each coordinated with at least one ligand comprising at least two sets of ortho-diimine groups arranged about an organic core. |
| FILED | Wednesday, May 06, 2015 |
| APPL NO | 15/309023 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/005 (20130101) C07F 1/08 (20130101) C07F 15/045 (20130101) Original (OR) Class C07F 15/065 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174064 | Chavez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | David E. Chavez (Ranchos de Taos, New Mexico); Susan Kloek Hanson (Los Alamos, New Mexico); Robert Jason Scharff (Los Alamos, New Mexico); Jacqueline Marie Veauthier (Los Alamos, New Mexico); Thomas Winfield Myers (Los Alamos, New Mexico) |
| ABSTRACT | Energetic materials that are photoactive or believed to be photoactive may include a conventional explosive (e.g. PETN, nitroglycerine) derivatized with an energetic UV-absorbing and/or VIS-absorbing chromophore such as 1,2,4,5-tetrazine or 1,3,5-triazine. Absorption of laser light having a suitably chosen wavelength may result in photodissociation, decomposition, and explosive release of energy. These materials may be used as ligands to form complexes. Coordination compounds include such complexes with counterions. Some having the formula M(L)n2+ were synthesized, wherein M is a transition metal and L is a ligand and n is 2 or 3. These may be photoactive upon exposure to a laser light beam having an appropriate wavelength of UV light, near-IR and/or visible light. Photoactive materials also include coordination compounds bearing non-energetic ligands; in this case, the counterion may be an oxidant such as perchlorate. |
| FILED | Thursday, January 11, 2018 |
| APPL NO | 15/868562 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 25/34 (20130101) C06B 41/00 (20130101) Detonating or Priming Devices; Fuses; Chemical Lighters; Pyrophoric Compositions C06C 7/00 (20130101) C06C 9/00 (20130101) Heterocyclic Compounds C07D 251/30 (20130101) C07D 257/08 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) C07F 15/025 (20130101) C07F 15/045 (20130101) C07F 15/065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174081 | Bishop et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Barney Bishop (Annandale, Virginia); Monique van Hoek (Centreville, Virginia) |
| ASSIGNEE(S) | George Mason Research Foundation, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Barney Bishop (Annandale, Virginia); Monique van Hoek (Centreville, Virginia) |
| ABSTRACT | Materials and methods for making and using cationic anti-microbial peptides (CAMPs), and compositions containing such peptides. |
| FILED | Friday, April 20, 2012 |
| APPL NO | 14/113158 |
| ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/17 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/001 (20130101) Original (OR) Class C07K 14/4723 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174088 | Zamora et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ferring B.V. (Hoofddorp, Netherlands); Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | Ferring B.V. (Hoofddrop, Netherlands) |
| INVENTOR(S) | Paul Zamora (Gaithersburg, Maryland); Brent Lee Atkinson (Highlands Ranch, Colorado); Xinhua Lin (Plainview, New York); Louis A. Pena (Poquott, New York) |
| ABSTRACT | A composition comprising a synthetic growth factor analogue comprising a non-growth factor heparin binding region, a linker and a sequence that binds specifically to a cell surface receptor and an osteoconductive material where the synthetic growth factor analogue is attached to and can be released from the osteoconductive material and is an amplifier/co-activator of osteoinduction. |
| FILED | Tuesday, November 21, 2017 |
| APPL NO | 15/819444 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1875 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/12 (20130101) A61L 27/16 (20130101) A61L 27/16 (20130101) A61L 27/22 (20130101) A61L 27/24 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/227 (20130101) A61L 27/507 (20130101) A61L 2430/02 (20130101) Peptides C07K 14/51 (20130101) C07K 14/4705 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 27/18 (20130101) C08L 89/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174244 | Bourret-Courchesne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Edith D. Bourret-Courchesne (Berkeley, California); Gregory A. Bizarri (San Francisco, California) |
| ABSTRACT | The present invention provides for a composition comprising an inorganic scintillator comprising a doped halide, useful for detecting nuclear material. |
| FILED | Thursday, April 17, 2014 |
| APPL NO | 14/255697 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/628 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174347 | Stephanopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Gregory Stephanopoulos (Winchester, Massachusetts); Devin Hedley Currie (Somerville, Massachusetts); Kristen Jean Fortnam (Somerville, Massachusetts) |
| ABSTRACT | Aspects of the invention relate to methods for producing lactic acid from organic waste, comprising contacting organic waste with a microbial community to form a fermentation mixture, and fermenting the fermentation mixture under controlled pH and temperature conditions for a time sufficient to produce lactic acid. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/142877 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/56 (20130101) Original (OR) Class C12P 39/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174408 | Muralidharan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Govindarajan Muralidharan (Knoxville, Tennessee); Bruce A. Pint (Knoxville, Tennessee) |
| ABSTRACT | An alumina-forming, high temperature creep resistant alloy is composed essentially of, in terms of weight percent: up to 10 Fe, 3.3 to 4.6 Al, 6 to 22 Cr, 0.68 to 0.74 Mn, 5.2 to 6.6 Mo, 0.4 to 1.2 Ti, up to 0.1 Hf, 0.005 to 0.05 La, 0.4 to 0.6 W, 0.1 to 0.35 C, up to 0.002 B, 0.001 to 0.02 N, balance Ni. |
| FILED | Monday, June 22, 2015 |
| APPL NO | 14/745740 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 19/056 (20130101) Original (OR) Class C22C 19/057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174975 | Feng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carrier Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | CARRIER CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Yinshan Feng (South Windsor, Connecticut); Jinliang Wang (Ellington, Connecticut); Futao Zhao (Farmington, Connecticut); Thomas D. Radcliff (Vernon, Connecticut); Parmesh Verma (South Windsor, Connecticut) |
| ABSTRACT | A heat transfer system includes a first two-phase heat transfer fluid vapor/compression circulation loop including a compressor, a heat exchanger condenser, an expansion device, and a heat absorption side of a heat exchanger evaporator/condenser. A first conduit in a closed fluid circulation loop circulates a first heat transfer fluid therethrough. A second two-phase heat transfer fluid circulation loop transfers heat to the first heat transfer fluid circulation loop through the heat exchanger evaporator/condenser, including a heat rejection side of the heat exchanger evaporator/condenser, a liquid pump, a liquid refrigerant reservoir located upstream of the liquid pump and downstream of the heat exchanger evaporator/condenser, and a heat exchanger evaporator. A second conduit in a closed fluid circulation loop circulates a second heat transfer fluid therethrough having an ASHRAE Class A toxicity and a Class 1 or 2L flammability rating. |
| FILED | Thursday, August 14, 2014 |
| APPL NO | 15/029743 |
| ART UNIT | 3744 — Static Structures, Supports and Furniture |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 9/002 (20130101) F25B 9/008 (20130101) F25B 23/006 (20130101) F25B 25/005 (20130101) Original (OR) Class F25B 39/00 (20130101) F25B 40/02 (20130101) F25B 41/00 (20130101) F25B 49/022 (20130101) F25B 2400/12 (20130101) F25B 2400/121 (20130101) F25B 2500/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175106 | Fontecchio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DREXEL UNIVERSITY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Adam K. Fontecchio (Downington, Pennsylvania); Sameet K. Shriyan (Philadelphia, Pennsylvania); Alyssa Bellingham (Philadelphia, Pennsylvania) |
| ABSTRACT | A holographic polymer dispersed liquid crystal (HPDLC) tunable filter exhibits switching times of no more than 20 microseconds. The HPDLC tunable filter can be utilized in a variety of applications. An HPDLC tunable filter stack can be utilized in a hyperspectral imaging system capable of spectrally multiplexing hyperspectral imaging data acquired while the hyperspectral imaging system is airborne. HPDLC tunable filter stacks can be utilized in high speed switchable optical shielding systems, for example as a coating for a visor or an aircraft canopy. These HPDLC tunable filter stacks can be fabricated using a spin coating apparatus and associated fabrication methods. |
| FILED | Tuesday, August 01, 2017 |
| APPL NO | 15/665596 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/51 (20130101) G01J 3/0237 (20130101) Original (OR) Class G01J 3/502 (20130101) Optical Elements, Systems, or Apparatus G02B 27/0103 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/13342 (20130101) G02F 1/13476 (20130101) G02F 2203/055 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/20 (20130101) G03F 7/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175391 | Stolz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Christopher Stolz (Lathrop, California); Jim Folta (Livermore, California); Paul B. Mirkarimi (Danville, California); Regina Soufli (Berkeley, California); Christopher C. Walton (Oakland, California); Justin Wolfe (Modesto, California); Carmen Menoni (Fort Collins, Colorado); Dinesh Patel (Fort Collins, Colorado) |
| ABSTRACT | Planarization of defects in laser mirror and other optical component manufacture is disclosed. The planarization is performed by first depositing a relatively thick planarization layer, then carrying out a sequential deposition and etch process. The technique takes advantage of the non-uniform material removal rate as a function of etchant incident angle, and effectively buries the inclusion in a thick film with a near planar top surface. The process enables faster, more reliable manufacture of a non-defective high fluence multilayer mirror particularly suitable for high energy laser applications. |
| FILED | Friday, January 25, 2013 |
| APPL NO | 14/434699 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 17/3417 (20130101) C03C 2218/33 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/08 (20130101) C23C 14/34 (20130101) C23C 14/3442 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 4/00 (20130101) Optical Elements, Systems, or Apparatus G02B 3/00 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/265 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175554 | Grice et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Warren P. Grice (Oak Ridge, Tennessee); Joseph M. Lukens (Knoxville, Tennessee); Nicholas A. Peters (Knoxville, Tennessee) |
| ABSTRACT | An apparatus for producing a single photon can comprise a modulator that modulates the wavelength of a pump beam based on wavelength of an idler photon of a signal/idler photon pair. A wavelength division multiplexer combines the modulated pump beam and the signal photon in a non-linear element to produce an output photon having a preselected wavelength based on signal photon wavelength and a wavelength of the modulated pump beam. |
| FILED | Friday, December 01, 2017 |
| APPL NO | 15/829349 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/35 (20130101) G02F 1/365 (20130101) G02F 1/3501 (20130101) Original (OR) Class G02F 1/3526 (20130101) G02F 1/3532 (20130101) G02F 1/3536 (20130101) G02F 2001/3503 (20130101) G02F 2001/3507 (20130101) G02F 2202/32 (20130101) G02F 2203/05 (20130101) Transmission H04B 10/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175906 | Muralimanohar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Naveen Muralimanohar (Santa Clara, California); Erik Ordentlich (San Jose, California); Cong Xu (Palo Alto, California) |
| ABSTRACT | In an example, in a method for encoding data within a crossbar memory array containing cells, bits of input data may be received. The received bits of data may be mapped to the cells in a row of the memory array, in which the cells are to be assigned to one of a low resistance state and a high resistance state. A subset of the mapped bits in the row may be grouped into a word pattern. The word pattern may be arranged such that more low resistance states are mapped to cells that are located closer to a voltage source of the row of the memory array than to cells that are located farther away from the voltage source. |
| FILED | Thursday, July 31, 2014 |
| APPL NO | 15/325118 |
| ART UNIT | 2132 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0638 (20130101) Original (OR) Class G06F 3/0679 (20130101) Static Stores G11C 7/1012 (20130101) G11C 13/0069 (20130101) G11C 2213/77 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176281 | Asaad et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Sameh W. Asaad (Briarcliff Manor, New York); Mohit Kapur (Sleepy Hollow, New York) |
| ABSTRACT | A method, system and computer program product are disclosed for generating clock signals for a cycle accurate FPGA based hardware accelerator used to simulate operations of a device-under-test (DUT). In one embodiment, the DUT includes multiple device clocks generating multiple device clock signals at multiple frequencies and at a defined frequency ratio; and the FPG hardware accelerator includes multiple accelerator clocks generating multiple accelerator clock signals to operate the FPGA hardware accelerator to simulate the operations of the DUT. In one embodiment, operations of the DUT are mapped to the FPGA hardware accelerator, and the accelerator clock signals are generated at multiple frequencies and at the defined frequency ratio of the frequencies of the multiple device clocks, to maintain cycle accuracy between the DUT and the FPGA hardware accelerator. In an embodiment, the FPGA hardware accelerator may be used to control the frequencies of the multiple device clocks. |
| FILED | Thursday, November 12, 2015 |
| APPL NO | 14/939411 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 9/455 (20130101) G06F 17/5027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176343 | Youd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | David W. Youd (Livermore, California); Domingo R. Colon, III (Dublin, California); Edward T. Seidl (Livermore, California) |
| ABSTRACT | A system for identifying IP ranges having a network address and a network address mask is provided. The system generates a collection of IP ranges. For each unique network address as defined by a maximum network address mask within provided IP addresses, the system adds to the collection an IP range for that unique network address. The added IP range may be defined by the unique network address and a network address mask that is set to the maximum network address mask. The system identifies groups of IP ranges of the collection to be represented by a combined IP range with a combined network address mask. For each group of IP ranges, the system removes from the collection the IP ranges within the group and adds to the collection the combined IP range with a network address and the combined network address mask. |
| FILED | Tuesday, October 13, 2015 |
| APPL NO | 14/882342 |
| ART UNIT | 2445 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 17/30312 (20130101) G06F 17/30339 (20130101) G06F 21/64 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0853 (20130101) H04L 41/0893 (20130101) H04L 43/14 (20130101) H04L 61/2061 (20130101) H04L 61/6095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176983 | Martin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Aiden Alexander Martin (Walnut Creek, California) |
| ABSTRACT | A method for produce a boron containing film by admitting a gaseous boron precursor into a vacuum chamber containing a substrate and directing an electron beam or ion beam into the vacuum chamber onto to the surface of the substrate. The electron beam or ion beam dissociates the gaseous boron precursor at the surface of the substrate creating non-volatile fragments that bind to the substrate surface forming a boron containing film. |
| FILED | Wednesday, October 11, 2017 |
| APPL NO | 15/729819 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/067 (20130101) C23C 14/221 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02175 (20130101) H01L 21/02205 (20130101) H01L 21/02266 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176991 | Lagally et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Max G. Lagally (Madison, Wisconsin); Thomas Francis Kuech (Madison, Wisconsin); Yingxin Guan (Madison, Wisconsin); Shelley A. Scott (Madison, Wisconsin); Abhishek Bhat (Madison, Wisconsin); Xiaorui Cui (Middleton, Wisconsin) |
| ABSTRACT | High-quality, single-crystalline silicon-germanium (Si(1-x)Gex) having a high germanium content is provided. Layers of the high-quality, single-crystalline silicon-germanium can be grown to high sub-critical thicknesses and then released from their growth substrates to provide Si(1-x)Gex films without lattice mismatch-induced misfit dislocations or a mosaic distribution of crystallographic orientations. |
| FILED | Thursday, July 06, 2017 |
| APPL NO | 15/643111 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/02 (20130101) C30B 29/08 (20130101) C30B 29/52 (20130101) C30B 29/68 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02395 (20130101) H01L 21/02461 (20130101) H01L 21/02463 (20130101) H01L 21/02532 (20130101) H01L 21/02694 (20130101) Original (OR) Class H01L 21/7813 (20130101) H01L 29/78 (20130101) H01L 29/165 (20130101) H01L 29/7378 (20130101) H01L 29/7786 (20130101) H01L 31/109 (20130101) H01L 31/1812 (20130101) H01L 31/1892 (20130101) H01L 31/035254 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177271 | Alivisatos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | A. Paul Alivisatos (Berkeley, California); Miquel Salmeron (Kensington, California); Yingjie Zhang (Urbana, Illinois); Daniel J. Hellebusch (Oakland, California) |
| ASSIGNEE(S) | the Regents of the University of California (Oakland, California) |
| INVENTOR(S) | A. Paul Alivisatos (Berkeley, California); Miquel Salmeron (Kensington, California); Yingjie Zhang (Urbana, Illinois); Daniel J. Hellebusch (Oakland, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to photodetectors. In one aspect, a photodetector device comprises a substrate, a polycrystalline layer disposed on the substrate, and a first electrode and a second electrode disposed on the polycrystalline layer. The polycrystalline layer comprises nanograins with grain boundaries between the nanograins. The nanograins comprise a semiconductor material. A doping element comprising a halogen is segregated at the grain boundaries. A length of the polycrystalline layer is between and separating the first electrode and the second electrode. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/359882 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/09 (20130101) H01L 31/0368 (20130101) H01L 31/1136 (20130101) H01L 31/1836 (20130101) H01L 31/1872 (20130101) Original (OR) Class H01L 31/1892 (20130101) H01L 31/02963 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177365 | Mane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Anil U. Mane (Naperville, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Joong Sun Park (Woodridge, Illinois); Jason R. Croy (Plainfield, Illinois) |
| ABSTRACT | The fabrication of robust interfaces between transition metal oxides and non-aqueous electrolytes is one of the great challenges of lithium ion batteries. Atomic layer deposition (ALD) of aluminum tungsten fluoride (AlWxFy) improves the electrochemical stability of LiCoO2. AlWxFy thin films were deposited by combining trimethylaluminum and tungsten hexafluoride. in-situ quartz crystal microbalance and transmission electron microscopy studies show that the films grow in a layer-by-layer fashion and are amorphous nature. Ultrathin AlWxFy coatings (<10 Å) on LiCoO2 significantly enhance stability relative to bare LiCoO2 when cycled to 4.4 V. The coated LiCoO2 exhibited superior rate capability (up to 400 mA/g) and discharge capacities at a current of 400 mA/g were 51% and 92% of the first cycle capacities for the bare and AlWxFy coated materials. These results open new possibilities for designing ultrathin and electrochemically robust coatings of metal fluorides via ALD to enhance the stability of Li-ion electrodes. |
| FILED | Wednesday, April 22, 2015 |
| APPL NO | 14/693719 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/30 (20130101) C23C 16/45531 (20130101) C23C 16/45555 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/366 (20130101) H01M 4/0421 (20130101) Original (OR) Class H01M 4/505 (20130101) H01M 4/628 (20130101) H01M 4/1391 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177378 | Aksay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vorbeck Materials Corp. (Jessup, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ilhan A. Aksay (Princeton, New Jersey); Daniel Dabbs (Princeton, New Jersey); Michael A. Pope (Kitchener, Canada) |
| ABSTRACT | Embodiments of the present invention relate to battery electrodes incorporating composites of graphene and selenium-sulfur compounds for improved rechargeable batteries. In one embodiment, a conductive composition comprises a conductive composition having a Se—S compound, a conductive additive. The Se—S compound is present as SexS8-x, wherein 0<x<8. |
| FILED | Friday, February 26, 2016 |
| APPL NO | 15/055505 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/74 (20130101) H01M 4/136 (20130101) H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 4/663 (20130101) H01M 4/667 (20130101) H01M 4/668 (20130101) H01M 4/5815 (20130101) Original (OR) Class H01M 10/052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177405 | Spatocco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Brian L. Spatocco (Cambridge, Massachusetts); Paul J. Burke (Framingham, Massachusetts); Donald R. Sadoway (Cambridge, Massachusetts) |
| ABSTRACT | An electrochemical cell and its method of operation includes an electrolyte having a binary salt system of an alkali hydroxide and a second alkali salt. The anode, cathode, and electrolyte may be in the molten phase. The cell is operational for both storing electrical energy and as a source of electrical energy as part of an uninterruptible power system. The cell is particularly suited to store electrical energy produced by a renewable energy source. |
| FILED | Friday, October 04, 2013 |
| APPL NO | 14/045967 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/20 (20130101) H01M 10/22 (20130101) H01M 10/39 (20130101) H01M 10/054 (20130101) H01M 10/399 (20130101) H01M 10/0562 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177419 | Christensen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert Bosch GmbH (Stuttgart, Germany) |
| ASSIGNEE(S) | Robert Bosch GmbH (Stuttgart, Germany) |
| INVENTOR(S) | John F. Christensen (Elk Grove, California); Reinhardt Klein (Mountain View, California); Abdul-Kader Srouji (San Francisco, California); Ashish Krupadanam (Cupertino, California); Anahita MirTabatabaei (San Francisco, California); Nikhil Ravi (Mountain View, California) |
| ABSTRACT | Methods and systems are described of managing a battery system. The battery system including at least one battery cell and one or more sensors configured to measure a temperature of the at least one battery cell. The method includes receiving a measurement of the temperature of the at least one battery cell, estimating an open circuit potential of the at least one battery cell, estimating a capacity fade of the at least one battery cell based on the open circuit potential of the at least one battery cell and a ratio of a change in the open circuit potential relative to a change in the temperature of the at least one battery cell, and regulating at least one of charging or discharging of the at least one battery cell based on the estimation of the capacity fade. |
| FILED | Thursday, March 17, 2016 |
| APPL NO | 15/072839 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/362 (20130101) G01R 31/3651 (20130101) G01R 31/3679 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/48 (20130101) H01M 10/425 (20130101) H01M 10/443 (20130101) H01M 10/482 (20130101) H01M 10/486 (20130101) H01M 10/613 (20150401) H01M 10/615 (20150401) H01M 10/623 (20150401) H01M 10/625 (20150401) H01M 10/633 (20150401) H01M 10/4257 (20130101) Original (OR) Class H01M 10/6567 (20150401) H01M 2010/4271 (20130101) H01M 2010/4278 (20130101) H01M 2220/20 (20130101) H01M 2220/30 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177421 | Saunders et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | James H. Saunders (Worthington, Ohio); Steven M. Risser (Reynoldsburg, Ohio); C. Alexander Morrow (Gahanna, Ohio) |
| ABSTRACT | Light is transmitted from a light source through or from a separator of a battery cell and received by one or more light detectors. The light that is normally transmitted through the separator is scattered, absorbed, wavelength-shifted or otherwise distorted by an impending fault in the vicinity of or within the separator. The change in light due to the impending fault is measured by a detector and a signal from the detector is processed to identify the impending fault so that a warning can be generated indicative of the impending fault. In particular, one or both of the light source and detector are enclosed within a battery cell housing and receive power from the electrodes of the battery cell. |
| FILED | Thursday, February 12, 2015 |
| APPL NO | 14/620635 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/59 (20130101) G01N 21/84 (20130101) G01N 21/95 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/48 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2220/10 (20130101) H01M 2220/20 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177647 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Fei (Fred) Wang (Oak Ridge, Tennessee); Burak Ozpineci (Oak Ridge, Tennessee); Sheng Zheng (Oak Ridge, Tennessee); Steven L. Campbell (Oak Ridge, Tennessee); Madhu Sudhan Chinthavali (Oak Ridge, Tennessee); Aleksandar D. Dimitrovski (Oak Ridge, Tennessee); Philip R. Irminger (Oak Ridge, Tennessee); Omer C. Onar (Oak Ridge, Tennessee); Larry E. Seiber (Oak Ridge, Tennessee); Leon M. Tolbert (Oak Ridge, Tennessee); Clifford P. White (Oak Ridge, Tennessee); Daniel J. Costinett (Oak Ridge, Tennessee); Zhi Li (Oak Ridge, Tennessee); Jingxin Wang (Oak Ridge, Tennessee); Fei Yang (Oak Ridge, Tennessee) |
| ABSTRACT | A direct current controller includes a rectifier configured to convert alternating current input into a direct current output. A converter electrically coupled to the rectifier generates a converted direct current voltage that regulates a converted direct current from the direct current output of the rectifier and synthesizes an ac component of an alternating current grid to counteract an induced back-emf. A direct current controller central controller coupled to the converter regulates the converted direct current. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/261106 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Systems for Regulating Electric or Magnetic Variables G05F 1/33 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/1807 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/12 (20130101) Original (OR) Class H02M 5/06 (20130101) H02M 7/217 (20130101) H02M 2003/1555 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177922 | Hamlet et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jason Hamlet (Albuquerque, New Mexico); Ryan Helinski (Albuquerque, New Mexico); Todd Bauer (Albuquerque, New Mexico); Lyndon G. Pierson (Albuquerque, New Mexico) |
| ABSTRACT | The various technologies presented herein relate to enabling a value generated based upon a physical unclonable function (PUF) response to be available as needed, while also preventing exposure of the PUF to a malicious entity. A masked PUF response can be generated based upon applying a function to a combination of the PUF response and a data file (e.g., a bitstream), and the masked PUF response is forwarded to a requesting entity, rather than the PUF response. Hence, the PUF is masked from any entity requiring access to the PUF. The PUF can be located in a FPGA, wherein the data file is a bitstream pertinent to one or more configurable logic blocks included in the FPGA. A first masked PUF response generated with a first data file can have a different value to a second masked PUF response generated with a second data file. |
| FILED | Tuesday, March 22, 2016 |
| APPL NO | 15/077594 |
| ART UNIT | 2493 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/57 (20130101) G06F 2221/034 (20130101) G06F 2221/2105 (20130101) G06F 2221/2153 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/32 (20130101) H04L 9/3221 (20130101) H04L 9/3278 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10178447 | Schwartz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | David E. Schwartz (San Carlos, California); Tse Nga Ng (Palo Alto, California); Gregory Whiting (Menlo Park, California); Anurag Ganguli (Milpitas, California); George Daniel (Palo Alto, California) |
| ABSTRACT | A sensor network system that includes a sensor array having a plurality of sensor units that include a plurality of sensor elements, each sensor element configured to generate an electrical signal in response to a chemical environment in the vicinity of the sensor unit. The set of electrical signals generated by the sensor elements of the sensor unit represents a measured signature of the environment in the vicinity of the sensor unit. An analyzer is configured to extract the measured signatures of each sensor unit from sensor unit information signals and to detect a presence and concentration of one or more of the gases of interest based on the measured signatures. |
| FILED | Thursday, July 23, 2015 |
| APPL NO | 14/806983 |
| ART UNIT | 2684 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/22 (20130101) Selecting H04Q 9/00 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/70 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10178749 | Finn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tibbar Plasma Technologies, Inc. (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TIBBAR PLASMA TECHNOLOGIES, INC. (Los Alamos, New Mexico) |
| INVENTOR(S) | John Finn (Los Alamos, New Mexico); Cihan Akcay (Los Alamos, New Mexico); Daniel Barnes (Lamy, New Mexico); Juan Fernandez (Los Alamos, New Mexico); William Gibson (Los Alamos, New Mexico); Aaron McEvoy (Los Alamos, New Mexico); Keith Moser (Libertyville, Illinois); Richard Nebel (Los Alamos, New Mexico); Liviu Popa-Simil (Los Alamos, New Mexico) |
| ABSTRACT | An apparatus and corresponding systems and methods for managing electric power, particularly a transformer system and method, and more specifically a transformer for direct current. An example apparatus includes a chamber configured to contain plasma. The apparatus includes input electrodes disposed at least partially within the chamber, and configured to receive a first direct current input into the chamber. The input electrodes are configured to cause the input direct current to induce motion in the plasma. Motion induced in the plasma transforms current flowing there-through. At output electrodes extend from the chamber. The output electrodes conduct a second direct current, from the induced motion in the plasma, for delivery from the chamber. |
| FILED | Thursday, October 27, 2016 |
| APPL NO | 15/336508 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10178756 | Rohwer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Lauren E. S. Rohwer (Albuquerque, New Mexico); James E. Martin (Tijeras, New Mexico) |
| ABSTRACT | The present invention relates to composite coatings including particles embedded in a matrix, as well as methods and uses thereof. In some examples, the particles are aligned to enhance mitigation of whisker formation from an underlying metal material. Such coatings can be applied to electrical components, thereby reducing the possibility of electrical short circuits from aberrant whisker growth. |
| FILED | Thursday, October 29, 2015 |
| APPL NO | 14/926545 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/04 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/10 (20130101) C08K 3/18 (20130101) C08K 7/00 (20130101) C08K 13/06 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 133/00 (20130101) C09D 163/00 (20130101) C09D 175/04 (20130101) C09D 183/04 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/00 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) H05K 1/032 (20130101) H05K 1/0213 (20130101) Original (OR) Class H05K 1/0306 (20130101) H05K 3/0091 (20130101) H05K 2201/0158 (20130101) H05K 2201/0162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10172362 | Wood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Thomas K. Wood (Port Matilda, Pennsylvania); Manish Kumar (State College, Pennsylvania); Thammajun L. Wood (Port Matilda, Pennsylvania) |
| ABSTRACT | Biofilms are provided which are capable of regulating their own thickness, reducing contamination and preventing biofouling. Constructs are introduced into bacteria that comprise nucleic acid molecules encoding an autoinducer synthase polypeptide, a transcriptional regulator and a biofilm dispersal protein. Nucleic acid molecules may also be introduced which encode a nitric oxide synthase, an epoxide hydrolase, or both. Biofilms of the bacteria may be used to reduce biofouling and contamination of a surface. |
| FILED | Tuesday, October 25, 2016 |
| APPL NO | 15/334168 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/02 (20130101) Original (OR) Class Peptides C07K 14/21 (20130101) C07K 14/245 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/00 (20130101) C12N 1/04 (20130101) C12N 9/14 (20130101) C12N 9/0075 (20130101) C12N 9/1029 (20130101) C12N 15/70 (20130101) C12N 15/74 (20130101) C12N 15/78 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/01 (20130101) Enzymes C12Y 114/13039 (20130101) C12Y 203/01184 (20130101) C12Y 303/02003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10172956 | Duvall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Craig L. Duvall (Nashville, Tennessee); Christopher E. Nelson (Nashville, Tennessee); James Kintzing (Nashville, Tennessee); Joshua M. Shannon (Nashville, Tennessee); Mukesh K. Gupta (Nashville, Tennessee); Scott A. Guelcher (Thompsons Station, Tennessee); Elizabeth J. Adolph (Nashville, Tennessee); Jeffrey M. Davidson (Nashville, Tennessee) |
| ABSTRACT | The presently-disclosed subject matter includes nanoparticles that comprise a plurality of assembled polymers. In some embodiments the polymers comprise a first block that includes hydrophilic monomers, the first block substantially forming an outer shell of the nanoparticle, and a second block that includes cationic monomers and hydrophobic monomers, the second block substantially forming a core of the nanoparticle. In some embodiments a polynucleotide is provided that is bound to the cationic monomers of the nanoparticle. The presently-disclosed subject matter also comprises methods for using the present nanoparticles to include RNAi in a cell as well as methods for making the present nanoparticles. |
| FILED | Monday, October 28, 2013 |
| APPL NO | 14/438596 |
| ART UNIT | 1674 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5138 (20130101) A61K 47/489 (20130101) Original (OR) Class A61K 47/48176 (20130101) A61K 47/48215 (20130101) A61K 47/48869 (20130101) A61K 48/00 (20130101) A61K 48/0041 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/34 (20130101) C08F 283/06 (20130101) C08F 2220/1825 (20130101) C08F 2438/03 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/126 (20130101) C08J 2353/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) C12N 15/113 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2310/351 (20130101) C12N 2320/30 (20130101) Enzymes C12Y 502/01008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173208 | Schrock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston College (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Richard R. Schrock (Winchester, Massachusetts); Annie J. King (Cambridge, Massachusetts); Yu Zhao (Brighton, Massachusetts); Margaret M. Flook (Cambridge, Massachusetts); Amir H. Hoveyda (Lincoln, Massachusetts) |
| ABSTRACT | The present invention relates generally to catalysts and processes for the Z-selective formation of internal olefin(s) from terminal olefin(s) via homo-metathesis reactions. |
| FILED | Thursday, January 05, 2017 |
| APPL NO | 15/399485 |
| ART UNIT | 1673 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/181 (20130101) B01J 31/1805 (20130101) B01J 31/1825 (20130101) B01J 31/2226 (20130101) B01J 31/2265 (20130101) B01J 31/2278 (20130101) B01J 31/2295 (20130101) Original (OR) Class B01J 2231/54 (20130101) B01J 2231/543 (20130101) B01J 2531/64 (20130101) B01J 2531/66 (20130101) B01J 2531/0266 (20130101) B01J 2531/0288 (20130101) B01J 2540/40 (20130101) B01J 2540/225 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/09 (20130101) Acyclic or Carbocyclic Compounds C07C 6/04 (20130101) C07C 6/04 (20130101) C07C 6/04 (20130101) C07C 6/04 (20130101) C07C 11/02 (20130101) C07C 13/28 (20130101) C07C 15/50 (20130101) C07C 41/30 (20130101) C07C 41/30 (20130101) C07C 43/166 (20130101) C07C 67/475 (20130101) C07C 67/475 (20130101) C07C 69/593 (20130101) C07C 209/64 (20130101) C07C 209/68 (20130101) C07C 209/68 (20130101) C07C 211/53 (20130101) C07C 303/40 (20130101) C07C 303/40 (20130101) C07C 311/18 (20130101) C07C 2531/18 (20130101) C07C 2531/22 (20130101) C07C 2601/14 (20170501) C07C 2601/16 (20170501) C07C 2602/10 (20170501) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) C07F 7/083 (20130101) C07F 11/00 (20130101) C07F 11/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173903 | Rimer et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Jeffrey D. Rimer (Houston, Texas); Manjesh Kumar (Houston, Texas) |
| ABSTRACT | Embodiments of the invention generally provide compositions of crystalline zeolite materials with tailored crystal habits and the methods for forming such crystalline zeolite materials. The methods for forming the crystalline zeolite materials include binding one or more zeolite growth modifiers (ZGMs) to the surface of a zeolite crystal, which results in the modification of crystal growth rates along different crystallographic directions, leading to the formation of zeolites having a tailored crystal habit. The improved properties enabled by the tailored crystal habit include a minimized crystal thickness, a shortened internal diffusion pathlength, and a greater step density as compared to a zeolite having the native crystal habit prepared by traditional processes. The tailored crystal habit provides the crystalline zeolite materials with an aspect ratio of about 4 or greater and crystal surfaces having a step density of about 25 steps/μm2 or greater. |
| FILED | Monday, June 16, 2014 |
| APPL NO | 14/305097 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/06 (20130101) B01J 29/035 (20130101) B01J 29/85 (20130101) B01J 29/7015 (20130101) B01J 35/002 (20130101) B01J 35/023 (20130101) B01J 35/0033 (20130101) B01J 47/00 (20130101) B01J 2229/62 (20130101) Non-metallic Elements; Compounds Thereof; C01B 39/04 (20130101) C01B 39/54 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/03 (20130101) C01P 2004/20 (20130101) C01P 2004/38 (20130101) C01P 2004/60 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/14 (20130101) C30B 29/14 (20130101) C30B 29/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10173945 | Buckner et al. |
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| FUNDED BY |
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| APPLICANT(S) | Steven Wayne Buckner (St. Louis, Missouri); Paul Jelliss (St. Louis, Missouri); Stephen Chung (Florissant, Missouri); Jacob M Laktas (St. Louis, Missouri); Gregory J Place (St. Louis, Missouri) |
| ASSIGNEE(S) | nanoMetallix LLC (Earth City, Missouri) |
| INVENTOR(S) | Steven Wayne Buckner (St. Louis, Missouri); Paul Jelliss (St. Louis, Missouri); Stephen Chung (Florissant, Missouri); Jacob M Laktas (St. Louis, Missouri); Gregory J Place (St. Louis, Missouri) |
| ABSTRACT | The present invention generally concerns isolated nanoparticles via the decomposition of a ternary metal hydride. More specifically, the present invention harnesses increased energy densities from two distinct nanoparticles isolated by a precise decomposition of LiAlH4. The singular material is air stable and is a nanocomposite of Li3AlH6 nanoparticles, elemental Al nanoparticles, an amount of Ti metal, and a nanoscale organic layer, which we call nMx. The nanocomposite protects and preserves the high energy densities of the core metals isolated from the controlled reaction and makes the nanoparticles safe to handle in air. The final composite is devoid of byproducts or phase transitions that will decrease the energy output of the nanocomposite. The method of the present invention creates a narrow distribution of nanoparticles that have unique burning characteristics useful for many applications. |
| FILED | Tuesday, July 25, 2017 |
| APPL NO | 15/659557 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/0078 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 45/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174031 | Wipf et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Peter Wipf (Pittsburgh, Pennsylvania); Stephen D. Meriney (Pittsburgh, Pennsylvania); Mary Liang (Pittsburgh, Pennsylvania) |
| ABSTRACT | Embodiments of calcium channel agonists, as well as methods of making and using the calcium channel agonists, are disclosed. The disclosed calcium channel agonists and corresponding salt forms have a structure according to general formula I: wherein each bond depicted as “ |
| FILED | Thursday, September 21, 2017 |
| APPL NO | 15/711715 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/52 (20130101) A61K 31/53 (20130101) A61K 31/53 (20130101) A61K 31/375 (20130101) A61K 31/375 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 473/16 (20130101) Original (OR) Class C07D 487/04 (20130101) Technologies for Adaptation to Climate Change Y02A 50/469 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174057 | Trivedi et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); Centre National De La Recherche Scientifique (Paris, France) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan); Centre National De La Recherche Scientifique (Paris, France) |
| INVENTOR(S) | Evan R. Trivedi (Farmington Hills, Michigan); Vincent L. Pecoraro (Ann Arbor, Michigan); Svetlana V. Eliseeva (Orleans, France); Stephane Petoud (Paris, France); Joseph Jankolovits (Oakland, California); Alexandra Foucault-Collet (San Diego, California); Ivana Martinic (Orleans, France) |
| ABSTRACT | A metallacrown complex has the formula: Ln(III)[12-MC-4]2[24-MC-8], wherein MC is a metallacrown macrocycle with a repeating sub-unit consisting of a transition metal (M(II)) and a hydroxamic acid (HA) ligand that produces a ligand-based charge transfer state when incorporated into the metallacrown complex. In an example of a method for making the metallacrown complex, a hydroxamic acid (HA) ligand that is to produce a ligand-based charge transfer state when incorporated into the metallacrown complex, a transition metal salt, and a rare-earth salt are dissolved in a solvent to form a solution. A base is added to the solution. The solution is stirred at a predetermined temperature for a predetermined time. The solution is exposed to a purification method to produce crystals of the metallacrown complex. |
| FILED | Friday, September 05, 2014 |
| APPL NO | 14/916822 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/003 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 2201/061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174159 | Pugh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Coleen Pugh (Akron, Ohio); Colin Wright (Kingwood, Texas); Carolyn Scherger (Cuyahoga Falls, Ohio); Xiang Yan (Suizhou, China PRC); Zheng Zhang (Changzhou, China PRC); Zewei Wang (Atlanta, Georgia) |
| ASSIGNEE(S) | The University of Akron (Akron, None) |
| INVENTOR(S) | Coleen Pugh (Akron, Ohio); Colin Wright (Kingwood, Texas); Carolyn Scherger (Cuyahoga Falls, Ohio); Xiang Yan (Suizhou, China PRC); Zheng Zhang (Changzhou, China PRC); Zewei Wang (Atlanta, Georgia) |
| ABSTRACT | Methods of functionalizing α-halogenated hydroxy acid-based polymers and coupling α-halogenated hydroxy acid-based polymers are provided. Suitable α-halogenated hydroxy acid-based polymers include α-halogenated polyesters and α-halogenated acrylate-based inimers. Methods include coupling α-halogenated polyesters and functionalizing α-halogenated polyesters without polymer cleavage. Certain α-halogenated hydroxy acid-based polymers may be functionalized, crosslinked or, intiate polymerization by inducing the α-halogenated hydroxy acid-based polymers to make a dioxolenium ion intermediate. The α-halogenated hydroxy acid-based polymers may also be functionalized using a radical trap. |
| FILED | Monday, November 02, 2015 |
| APPL NO | 15/522487 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/91 (20130101) C08G 63/682 (20130101) C08G 63/912 (20130101) C08G 63/6822 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174161 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Ft. Collins, Colorado) |
| INVENTOR(S) | Eugene Y. Chen (Ft. Collins, Colorado); Jian-Bo Zhu (Ft. Collins, Colorado) |
| ABSTRACT | B/N Lewis pairs have been discovered to catalyze rapid epimerization of meso-lactide (LA) or LA diastereomers quantitatively into rac-LA. The obtained rac-LA can be kinetically polymerized into poly( |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/756670 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 405/04 (20130101) C07D 515/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/08 (20130101) C08G 63/823 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 2207/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174242 | Thomas et al. |
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| FUNDED BY |
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| APPLICANT(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| ASSIGNEE(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| INVENTOR(S) | Alan C. Thomas (Yardley, Pennsylvania); Yuming Xie (Sugar Land, Texas); Jonathan Melman (Lexington, Kentucky); Robert Nordsell (Lexington, Kentucky) |
| ABSTRACT | Thioaluminate phosphor particles having a coating comprising or consisting essentially of a nitride, and methods for making such phosphor particles, are disclosed. Phosphor-converted light emitting diodes may comprise such coated phosphor particles. The nitride coatings on the thioaluminate phosphor particles provide a significantly improved barrier to water compared, to an aluminum oxide coating, and extend the operational lifetime of such a phosphor-converted light emitting diode. |
| FILED | Wednesday, May 30, 2018 |
| APPL NO | 15/993116 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) Original (OR) Class C09K 11/77 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174305 | Edd et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jon F. Edd (Arlington, Massachusetts); Mehmet Toner (Charlestown, Massachusetts); Dino DiCarlo (Los Angeles, California); Daniel Irimia (Charlestown, Massachusetts) |
| ABSTRACT | Microfluidic devices and methods for the encapsulation of particles within liquid droplets are disclosed. The new methods and devices form 1-100 picoliter-size monodisperse droplets containing the particles, such as single cells, encapsulated in individual liquid droplets. The particles can be encapsulated in droplets of a fluid by passing a fluid containing the particles through a high aspect-ratio microchannel to order the particles in the fluid, followed by forming the fluid into droplets. The resulting fraction of the liquid droplets with a single particle (e.g., a cell) is higher than the corresponding fraction of single-particle liquid droplets predicted by Poisson statistics. |
| FILED | Monday, June 12, 2017 |
| APPL NO | 15/620519 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174338 | Carrington et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | James C. Carrington (St. Louis, Missouri); Edwards Allen (O'Fallon, Missouri) |
| ABSTRACT | A method to generate siRNAs in vivo is described, as are constructs and compositions useful in the method. The method does not depend on the use of DNA or synthetic constructs that contain inverted duplications or dual promoters so as to form perfect or largely double-stranded RNA. Rather, the method depends on constructs that yield single-stranded RNA transcripts, and exploits endogenous or in vivo-produced miRNAs or siRNAs to initiate production of siRNAs. The miRNAs or siRNAs guide cleavage of the transcript and set the register for production of siRNAs (usually 21 nucleotides in length) encoded adjacent to the initiation cleavage site within the construct. The method results in specific formation of siRNAs of predictable size and register (phase) relative to the initiation cleavage site. The method can be used to produce specific siRNAs in vivo for inactivation or suppression of one or more target genes or other entities, such as pathogens. |
| FILED | Tuesday, May 24, 2016 |
| APPL NO | 15/163573 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/8218 (20130101) C12N 15/8245 (20130101) C12N 15/8246 (20130101) C12N 15/8247 (20130101) C12N 15/8251 (20130101) C12N 15/8261 (20130101) C12N 15/8271 (20130101) C12N 15/8274 (20130101) C12N 15/8279 (20130101) Original (OR) Class C12N 15/8281 (20130101) C12N 15/8283 (20130101) C12N 15/8285 (20130101) C12N 2310/14 (20130101) C12N 2320/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175123 | Lin et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Qiao Lin (New York, New York); Bin Wang (New York, New York); Yuan Jia (New York, New York) |
| ABSTRACT | MEMS-based calorimeter including two microchambers supported in a thin film substrate formed on a polymeric layer is provided. The thin film substrate includes a thermoelectric sensor configured to measure temperature differential between the two microchambers, and also includes a thermally stable and high strength polymeric diaphragm. Methods for fabricating the MEMS-based calorimeter, as well as methods of using the calorimeter to measure thermal properties of materials, such as biomolecules, or thermodynamic properties of chemical reactions or physical interactions, are also provided. |
| FILED | Thursday, December 03, 2015 |
| APPL NO | 14/957869 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/006 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/4893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175215 | Ozcan et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Aydogan Ozcan (Los Angeles, California); Bingen Cortazar (Los Angeles, California); Hatice Ceylan Koydemir (Los Angeles, California); Derek Tseng (Buena Park, California); Steve Feng (Danville, California) |
| ABSTRACT | A system for measuring chlorophyll concentration in a leaf sample includes a leaf-holding illuminator device with a main body containing a power source, a plurality of switchable light sources emitting light at different spectra (e.g., red and white light from a broadband light source), and a cap detachably secured to the main body using one or more fastening means. The leaf sample is interposed between the main body and the cap and held in place during imaging. The system includes a mobile electronic device having a camera configured to capture an image of the leaf illuminated by the plurality of switchable light sources, the mobile electronic device having wireless connectivity to a network and an application contained therein configured to transfer the images to a remote sever or computer via the network for data processing. A final chlorophyll index value is calculated based on the transferred images. |
| FILED | Monday, December 21, 2015 |
| APPL NO | 15/538309 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) G01N 21/84 (20130101) G01N 21/274 (20130101) G01N 33/0098 (20130101) Original (OR) Class G01N 2021/0125 (20130101) G01N 2021/8466 (20130101) G01N 2201/0221 (20130101) G01N 2201/0627 (20130101) G01N 2201/0634 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/22 (20130101) G06K 9/00657 (20130101) G06K 9/2027 (20130101) G06K 9/2054 (20130101) G06K 9/4661 (20130101) G06K 9/6202 (20130101) Image Data Processing or Generation, in General G06T 7/90 (20170101) Selecting H04Q 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175389 | Steinhardt et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Paul J. Steinhardt (Princeton, New Jersey); Salvatore Torquato (Princeton, New Jersey); Marian Florescu (Guildford, United Kingdom) |
| ABSTRACT | The invention provides an article of manufacture, and methods of designing and making the article. The article permits or prohibits waves of energy, especially photonic/electromagnetic energy, to propagate through it, depending on the energy band gaps built into it. The structure of the article may be reduced to a pattern of points having a hyperuniform distribution. The point-pattern may exhibit a crystalline symmetry, a quasicrystalline symmetry or may be aperiodic. In some embodiments, the point pattern exhibits no long-range order. Preferably, the point-pattern is isotropic. In all embodiments, the article has a complete, TE- and TM-optimized band-gap. The extraordinary transmission phenomena found in the disordered hyperuniform photonic structures of the invention find use in optical micro-circuitry (all-optical, electronic or thermal switching of the transmission), near-field optical probing, thermophotovoltaics, and energy-efficient incandescent sources. |
| FILED | Thursday, September 29, 2016 |
| APPL NO | 15/280150 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/00 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/17 (20130101) Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) Original (OR) Class G02B 5/3025 (20130101) G02B 6/125 (20130101) G02B 6/1225 (20130101) G02B 27/0012 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/16 (20130101) H01L 33/0058 (20130101) H01L 33/0095 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49993 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175547 | Chanda et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | Debashis Chanda (Orlando, Florida); Daniel Franklin (Orlando, Florida) |
| ABSTRACT | Dynamic, color-changing surfaces have many applications including but not limited to displays, wearables, and active camouflage. Plasmonic nanostructures can fill this role with the advantages of ultra-small pixels, high reflectivity, and post-fabrication tuning through control of the surrounding media. However, while post-fabrication tuning have yet to cover a full red-green-blue (RGB) color basis set with a single nanostructure of singular dimensions, the present invention contemplates a novel LC-based apparatus and methods that enable such tuning and demonstrates a liquid crystal-plasmonic system that covers the full red/green/blue (RGB) color basis set, as a function only of voltage. This is accomplished through a surface morphology-induced, polarization dependent, plasmonic resonance and a combination of bulk and surface liquid crystal effects that manifest at different voltages. The resulting LC-plasmonic system provides an unprecedented color range for a single plasmonic nanostructure, eliminating the need for the three spatially static sub-pixels of current displays. The system's compatibility with existing LCD technology is possible by integrating it with a commercially available thin-film-transistor (TFT) array. The imprinted surface readily interfaces with computers to display images as well as video. |
| FILED | Wednesday, April 04, 2018 |
| APPL NO | 15/945184 |
| ART UNIT | 2871 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/1395 (20130101) Original (OR) Class G02F 1/133533 (20130101) G02F 1/133604 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175705 | Reda et al. |
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| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
| INVENTOR(S) | Sherief Reda (Providence, Rhode Island); Abdullah Nowroz (Providence, Rhode Island); Kapil Dev (Providence, Rhode Island) |
| ABSTRACT | This invention relates to a power mapping and modeling system for integrated circuits. An automated process includes determining a floor plan of the integrated circuit, dividing the integrated circuit into blocks based on the floor plan, pumping oil through an inlet valve, over the integrated circuit, and out an outlet valve to create a simulated oil-based cooling system, injecting a plurality of power pulses across the integrated circuit, applying infrared image techniques to the integrated circuit to create measured thermal images for the simulated oil-based cooling system, setting up a finite-element model (FEM) to estimate entries in a first thermal-to-power modeling matrix for the simulated oil-based cooling system, determining and storing performance monitoring counter (PMC) measurements related to power consumptions of the blocks of the integrated circuit, reconstructing a power dissipation for the simulated oil-based cooling system by using a thermal map for the simulated oil-based cooling system system, using the power dissipation of the simulated oil-based cooling system, the FEM, and the PMC measurements to create a thermal map for a copper based cooling system, and creating a final thermal-to-power model for the integrated circuit from the thermal map for the model copper based cooling system. |
| FILED | Tuesday, February 18, 2014 |
| APPL NO | 14/183384 |
| ART UNIT | 2196 — Interprocess Communication and Software Development |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 23/1917 (20130101) Original (OR) Class Electric Digital Data Processing G06F 1/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176009 | Flikkema |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents for Northern Arizona Univ (, None) |
| ASSIGNEE(S) | Arizona Board of Regents acting for and on behalf of Northern Arizona University (Flagstaff, Arizona) |
| INVENTOR(S) | Paul G. Flikkema (Flagstaff, Arizona) |
| ABSTRACT | A system for optimizing energy efficiency of an embedded system. A hardware abstraction layer (HAL) is coupled to hardware of an embedded system. An energy hardware abstraction layer (eHAL) couples to the hardware and to the HAL. A hypervisor couples to the HAL and to the eHAL. One or more applications couple to the hypervisor, the HAL and the eHAL. The eHAL measures energy use of the embedded system, constructs a model of energy use of the embedded system and, using the model, determines how to one of reduce and minimize energy use of the embedded system. The hypervisor is configured to alter one or more hardware parameters to one of reduce and minimize energy use of the embedded system as the embedded system performs one or more tasks. In implementations a real time operating system (RTOS) is coupled to the one or more applications and to the hypervisor. |
| FILED | Monday, October 03, 2016 |
| APPL NO | 15/284439 |
| ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45504 (20130101) G06F 9/45558 (20130101) Original (OR) Class G06F 2009/45583 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176260 | Mahapatra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Amogh Mahapatra (Santa Clara, California); Nisheeth Srivastava (Avon, Connecticut); Jaideep Srivastava (Plymouth, Minnesota) |
| ABSTRACT | A computing device may determine, based at least in part on one or more semantic exemplars associated with a digital object, a level of incongruity for the digital object, and output an indication of the level of incongruity for the digital object. For instance, a system may provide a web application that can support hedonic web surfing. By modeling Internet users as active information foragers instead of random surfers, a system may obtain quantitative measures of digital objects that users may find psychologically stimulating. The system may utilize a quantitative measure of the conceptual incongruity of digital objects that may predict how interesting users will find an object. |
| FILED | Tuesday, February 10, 2015 |
| APPL NO | 14/618838 |
| ART UNIT | 2168 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 17/2785 (20130101) G06F 17/3053 (20130101) G06F 17/3069 (20130101) G06F 17/30315 (20130101) G06F 17/30321 (20130101) G06F 17/30663 (20130101) G06F 17/30684 (20130101) G06F 17/30731 (20130101) G06F 17/30864 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176299 | Torres et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); Indiana University of Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey); INDIANA UNIVERSITY RESEARCH and TECHNOLOGY CORPORATION (Indianaplis, Indiana) |
| INVENTOR(S) | Elizabeth B. Torres (Piscataway, New Jersey); Jorge Jose-Valenzuela (Bloomington, Indiana) |
| ABSTRACT | The present invention provides objective methods of diagnosis and behavioral treatments of neurological disorders such as autism spectral disorders and Parkinson's disease. |
| FILED | Tuesday, November 13, 2012 |
| APPL NO | 14/354796 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/11 (20130101) A61B 5/0015 (20130101) A61B 5/40 (20130101) A61B 5/162 (20130101) A61B 5/168 (20130101) A61B 5/1104 (20130101) A61B 5/1114 (20130101) A61B 5/1124 (20130101) A61B 5/1125 (20130101) A61B 5/1128 (20130101) A61B 5/4076 (20130101) A61B 5/4082 (20130101) A61B 5/4088 (20130101) A61B 5/4094 (20130101) A61B 5/4848 (20130101) A61B 5/7264 (20130101) A61B 5/7275 (20130101) A61B 5/7278 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) G06F 19/325 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 50/20 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176324 | Davidson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Jack W. Davidson (Charlottesville, Virginia); Jason D. Hiser (Charlottesville, Virginia) |
| ABSTRACT | Method, system and computer program product for applying existing anti-tampering and obfuscation techniques to virtual machine technology and offers several distinct advantages. The anti-tampering and obfuscation transforms can be applied continuously to prevent adversaries from gaining information about the program through emulation or dynamic analysis. In addition, the encryption can be used to prevent hackers from gaining information using static attacks. The use of a virtual machine also allows for low overhead execution of the obfuscated binaries as well as finer adjustment of the amount of overhead that can be tolerated. In addition, more protection can be applied to specific portions of the application that can tolerate slowdown. The in-corporation of a virtual machine also makes it easy to extend the technology to integrate new developments and resistance mechanisms, leading to less development time, increased savings, and quicker deployment. |
| FILED | Thursday, July 21, 2016 |
| APPL NO | 15/215994 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/10 (20130101) G06F 21/14 (20130101) G06F 21/52 (20130101) G06F 21/53 (20130101) G06F 21/57 (20130101) G06F 21/562 (20130101) Original (OR) Class G06F 21/572 (20130101) G06F 21/602 (20130101) G06F 2221/033 (20130101) G06F 2221/0724 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 2209/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176408 | Paik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David S. Paik (Half Moon Bay, California); Andrew J. Buckler (Wenham, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts) |
| ASSIGNEE(S) | Elucid Bioimaging Inc. (Wenham, Massachusetts) |
| INVENTOR(S) | David S. Paik (Half Moon Bay, California); Andrew J. Buckler (Wenham, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Friday, December 04, 2015 |
| APPL NO | 14/959732 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00147 (20130101) G06K 9/6296 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176571 | Shi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jianing V. Shi (Houston, Texas); Aswin C. Sankaranarayanan (Houston, Texas); Christoph Emanuel Studer (Houston, Texas); Richard G. Baraniuk (Houston, Texas) |
| ABSTRACT | A compressive sensing system for dynamic video acquisition. The system includes a video signal interface including a compressive imager configured to acquire compressive sensed video frame data from an object, a video processing unit including a processor and memory. The video processing unit is configured to receive the compressive sensed video frame data from the video signal interface. The memory comprises computer readable instructions that when executed by the processor cause the processor to generate a motion estimate from the compressive sensed video frame data and generate dynamical video frame data from the motion estimate and the compressive sensed video frame data. The dynamical video frame data may be output. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/376397 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/20 (20130101) G06T 11/005 (20130101) G06T 2207/10016 (20130101) Pictorial Communication, e.g Television H04N 5/77 (20130101) H04N 19/426 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176991 | Lagally et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Max G. Lagally (Madison, Wisconsin); Thomas Francis Kuech (Madison, Wisconsin); Yingxin Guan (Madison, Wisconsin); Shelley A. Scott (Madison, Wisconsin); Abhishek Bhat (Madison, Wisconsin); Xiaorui Cui (Middleton, Wisconsin) |
| ABSTRACT | High-quality, single-crystalline silicon-germanium (Si(1-x)Gex) having a high germanium content is provided. Layers of the high-quality, single-crystalline silicon-germanium can be grown to high sub-critical thicknesses and then released from their growth substrates to provide Si(1-x)Gex films without lattice mismatch-induced misfit dislocations or a mosaic distribution of crystallographic orientations. |
| FILED | Thursday, July 06, 2017 |
| APPL NO | 15/643111 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/02 (20130101) C30B 29/08 (20130101) C30B 29/52 (20130101) C30B 29/68 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02395 (20130101) H01L 21/02461 (20130101) H01L 21/02463 (20130101) H01L 21/02532 (20130101) H01L 21/02694 (20130101) Original (OR) Class H01L 21/7813 (20130101) H01L 29/78 (20130101) H01L 29/165 (20130101) H01L 29/7378 (20130101) H01L 29/7786 (20130101) H01L 31/109 (20130101) H01L 31/1812 (20130101) H01L 31/1892 (20130101) H01L 31/035254 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177287 | Melman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| ASSIGNEE(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| INVENTOR(S) | Jonathan Melman (Lexington, Kentucky); Robert Nordsell (Lexington, Kentucky); Kristen Baroudi (Lexington, Kentucky); Yong Bok Go (Lexington, Kentucky); Eric Bretschneider (Corinth, Texas); Alan C. Thomas (Yardley, Pennsylvania); Evan Thomas (Lexington, Kentucky) |
| ABSTRACT | Phosphors emitting green light over a narrow wavelength range may be used to broaden the gamut of display devices. In one aspect, a light emitting device comprises a light emitting solid state device emitting blue or violet light, a first phosphor that absorbs blue or violet light emitted by the light emitting solid state device and in response emits green light in a spectral band having a peak at wavelength λG and a height of one half its peak on a long wavelength edge of the band at wavelength λGhalf; and a second phosphor that absorbs blue or violet light emitted by the light emitting solid state device and in response emits red light in a spectral band having a peak at wavelength λR and a height of one half its peak on a short wavelength edge of the band at wavelength λRhalf. The ratio (λRhalf−λGhalf)/(λR−λG) is greater than 0.70. |
| FILED | Thursday, May 17, 2018 |
| APPL NO | 15/982193 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/56 (20130101) C09K 11/62 (20130101) C09K 11/64 (20130101) C09K 11/0838 (20130101) C09K 11/7728 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/504 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177325 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Jing Li (Cranbury, New Jersey); Xiao Zhang (Piscataway, New Jersey); George Z. Wei (North Brunswick, New Jersey); Wei Liu (New Brunswick, New Jersey) |
| ABSTRACT | Inorganic-organic hybrid IB-VII semiconductor compounds, in which a Group IB transition metal halide salt is coordinated with an organic heteroaromatic ligand, wherein at least one ring atom of said heteroaromatic ligand is a heteroatom independently selected from N, O and S and the Group IB metal of the halide salt is coordinated to a ring heteroatom. Also disclosed are semiconductor and light emitting devices comprising these materials, including light emitting diodes, and methods of preparing these materials and devices. |
| FILED | Friday, June 13, 2014 |
| APPL NO | 14/896870 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) C07F 1/10 (20130101) C07F 1/12 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/188 (20130101) C09K 2211/1022 (20130101) C09K 2211/1029 (20130101) C09K 2211/1044 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/502 (20130101) H01L 51/009 (20130101) Original (OR) Class H01L 51/0091 (20130101) H01L 51/5016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10178124 | Mookiah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Prathaban Mookiah (San Diego, California); Kapil R. Dandekar (Philadelphia, Pennsylvania); John MacLaren Walsh (Philadelphia, Pennsylvania); Rachel Greenstadt (Philadelphia, Pennsylvania) |
| ABSTRACT | Channel based authentication schemes for intrusion detection that operates at the physical layer are described that apply the capabilities of a pattern reconfigurable antenna for improved performance. Performance gains are achieved by the schemes as a function of the number of antenna modes. The first scheme relies on a channel based fingerprint for differentiating between transmitters whereas another scheme poses the intruder detection problem as a generalized likelihood ratio (GLR) test problem that operates on the channel realizations corresponding to different modes present in a reconfigurable antenna. The benefits of these two schemes over single element antennas are demonstrated. General guidelines are provided on how to choose the different elements of the decision metric in order to realize better performance for physical layer based authentication schemes based on any diversity scheme. |
| FILED | Friday, December 23, 2016 |
| APPL NO | 15/390134 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) H04L 63/1416 (20130101) H04L 63/1483 (20130101) Original (OR) Class Wireless Communication Networks H04W 12/06 (20130101) H04W 12/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10172933 | Rieder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Aida E. Rieder (Westbrook, Connecticut); William M. Fischer (Santa Fe, New Mexico); Devendra K. Rai (Old Saybrook, Connecticut) |
| ABSTRACT | Synthetic foot-and-mouth disease virus (FMDV) mosaic polypeptides, and nucleic acid molecules encoding the mosaic polypeptides, are described. The mosaic polypeptides have greater T-cell epitope coverage than naturally occurring FMDV polypeptides, and include common FMDV epitopes, but exclude rare FMDV epitopes. When included as part of an FMDV genome, the mosaic polypeptides permit virus replication and assembly into FMDV particles. The mosaic polypeptide and nucleic acid compositions can be used to elicit immune responses that provide protection against a broad range of serotype A FMDV strains. |
| FILED | Tuesday, October 17, 2017 |
| APPL NO | 15/785875 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/135 (20130101) Original (OR) Class A61K 2039/55566 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/32122 (20130101) C12N 2770/32134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174338 | Carrington et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | James C. Carrington (St. Louis, Missouri); Edwards Allen (O'Fallon, Missouri) |
| ABSTRACT | A method to generate siRNAs in vivo is described, as are constructs and compositions useful in the method. The method does not depend on the use of DNA or synthetic constructs that contain inverted duplications or dual promoters so as to form perfect or largely double-stranded RNA. Rather, the method depends on constructs that yield single-stranded RNA transcripts, and exploits endogenous or in vivo-produced miRNAs or siRNAs to initiate production of siRNAs. The miRNAs or siRNAs guide cleavage of the transcript and set the register for production of siRNAs (usually 21 nucleotides in length) encoded adjacent to the initiation cleavage site within the construct. The method results in specific formation of siRNAs of predictable size and register (phase) relative to the initiation cleavage site. The method can be used to produce specific siRNAs in vivo for inactivation or suppression of one or more target genes or other entities, such as pathogens. |
| FILED | Tuesday, May 24, 2016 |
| APPL NO | 15/163573 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/8218 (20130101) C12N 15/8245 (20130101) C12N 15/8246 (20130101) C12N 15/8247 (20130101) C12N 15/8251 (20130101) C12N 15/8261 (20130101) C12N 15/8271 (20130101) C12N 15/8274 (20130101) C12N 15/8279 (20130101) Original (OR) Class C12N 15/8281 (20130101) C12N 15/8283 (20130101) C12N 15/8285 (20130101) C12N 2310/14 (20130101) C12N 2320/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174378 | Rudell, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); CORNELL UNIVERSITY (Ithaca, New York); THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (Auckland, New Zealand); KATHOLIEKE UNIVERSITEIT LEUVEN (Heverlee, Belgium) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Cornell University (Ithaca, New York); The New Zealand Institute for Plant and Food Research (Auckland, New Zealand); Katholieke Universiteit (Leuven, Belgium) |
| INVENTOR(S) | David R. Rudell, Jr. (Wanatchee, Washington); Rachel S. Leisso (Wanatchee, Washington); James P. Mattheis (Wanatchee, Washington); James J. Giovannoni (Ithaca, New York); Nigel E. Gapper (Dryden, New York); Nicolai M. Bart (Heusden, Belgium); Chris B. Watkins (Ithaca, New York); Jason W. Johnston (Havelock North, New Zealand); Maarten L. Hertog (Scherpenheuvel, Belgium); Robert J. Schaffer (Auckland, New Zealand) |
| ABSTRACT | The present invention is a tool for diagnosis and prediction using biomarker-based risk assessment for chilling-related disorders of Rosaceous fruit crops including apple and pear. Provided are methodology and genes whose relative and absolute expression can accurately indicate disorder risk throughout the production and supply chain of these crops. This technology describes a necessary and novel management tool for stakeholders producing, servicing, or retailing these crops. |
| FILED | Monday, March 14, 2016 |
| APPL NO | 15/069952 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 1/6895 (20130101) C12Q 2600/13 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Electric Digital Data Processing G06F 19/18 (20130101) G06F 19/20 (20130101) G06F 19/22 (20130101) Computer Systems Based on Specific Computational Models G06N 5/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175170 | Kennedy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ian M. Kennedy (Davis, California); Sudheendra Lakshmana (Davis, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ian M. Kennedy (Davis, California); Sudheendra Lakshmana (Davis, California) |
| ABSTRACT | Core-shell nanoparticles comprises a phosphorescent core and metal shell comprising at least two metals The phosphorescent core may comprise an up converting phosphor. The phosphorescent core may comprise a trivalent rare earth cation. The phosphorescent core further may comprise a monovalent alkali metal. The phosphorescent core may optionally comprises a second and also optionally a third trivalent rare earth cation. |
| FILED | Friday, December 16, 2011 |
| APPL NO | 13/993658 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 33/38 (20130101) A61K 49/0015 (20130101) A61K 49/0065 (20130101) Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/20 (20141001) B42D 2035/24 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) C09K 11/77 (20130101) C09K 11/7766 (20130101) Pulp Compositions; Preparation Thereof Not Covered by Subclasses D21C or D21D; Impregnating or Coating of Paper; Treatment of Finished Paper Not Covered by Class B31 or Subclass D21G; Paper Not Otherwise Provided for D21H 15/02 (20130101) D21H 17/63 (20130101) D21H 19/02 (20130101) D21H 19/06 (20130101) D21H 21/48 (20130101) D21H 21/52 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP30062 | Finn |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Chad E. Finn (Corvallis, Oregon) |
| ABSTRACT | A new and distinct blackberry cultivar that originated from seed produced from a cross between the female blackberry plant ‘ORUS 1393-1’ (unpatented) and the male blackberry plant ‘Triple Crown’ (unpatented). This new blackberry is unique in that it contains all three commercial blackberry types (trailing, erect, and semi-erect) in its pedigree as either a parent or a grandparent. This new blackberry cultivar can be distinguished by being early ripening for a semi-erect blackberry, by its medium-large sized, firm berries with tough skin and very good flavor, by its medium to high yields borne on a vigorous plant with a semi-erect type growth habit and by its completely thornless canes. |
| FILED | Tuesday, June 20, 2017 |
| APPL NO | 15/731505 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/203 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP30063 | Finn |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Chad E. Finn (Corvallis, Oregon) |
| ABSTRACT | A new and distinct blackberry cultivar that originated from seed produced from a cross between the female blackberry plant ‘NZ 9629R-1’ (unpatented) and the male parent blackberry plant ‘ORUS 1939-4’ (unpatented). This new blackberry cultivar can be distinguished by its very large, many petaled, and attractive flowers, medium to high yields of large and very sweet flavored berries with good firmness and color and that are early ripening, and the trailing plant is completely thornless. |
| FILED | Tuesday, March 28, 2017 |
| APPL NO | 15/530950 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/7499 (20180501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10174198 | Jolley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott T. Jolley (Titusville, Florida); Martha K. Williams (Titusville, Florida); Tracy L. Gibson (Melbourne, Florida); Trent M. Smith (Satellite Beach, Florida); Anne J. Caraccio (Cape Canaveral, Florida); Wenyan Li (Orlando, Florida) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Scott T. Jolley (Titusville, Florida); Martha K. Williams (Titusville, Florida); Tracy L. Gibson (Melbourne, Florida); Trent M. Smith (Satellite Beach, Florida); Anne J. Caraccio (Cape Canaveral, Florida); Wenyan Li (Orlando, Florida) |
| ABSTRACT | Materials based on low melt polyimide, polyurea, or polyurethane chemistry have been developed which exhibit self-healing properties. These high performance polymers can be utilized either by themselves or in combination with microcapsule technology to deliver self-healing properties to electrical wire insulation or in other high performance, thin wall technologies such as inflatable structures. |
| FILED | Thursday, June 14, 2012 |
| APPL NO | 13/523806 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/02 (20130101) B32B 7/04 (20130101) B32B 27/08 (20130101) B32B 27/34 (20130101) B32B 2379/08 (20130101) B32B 2457/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/61 (20130101) C08G 18/755 (20130101) C08G 18/5024 (20130101) C08G 18/7621 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 9/10 (20130101) Compositions of Macromolecular Compounds C08L 75/02 (20130101) C08L 79/08 (20130101) Original (OR) Class Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/306 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/1379 (20150115) Y10T 428/24942 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174780 | Hofmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Douglas C. Hofmann (Altadena, California); Samuel C. Bradford (Pasadena, California) |
| ABSTRACT | Systems and methods in accordance with embodiments of the invention operate to structurally interrelate two components using inserts made from metallic glass-based materials. In one embodiment, a method of structurally interrelating two components includes: forming an insert from a metallic glass-based composition; where the formed insert includes a metallic glass-based material; affixing the insert to a first component; and structurally interrelating the second component to the first component using the insert. |
| FILED | Friday, March 11, 2016 |
| APPL NO | 15/067561 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2009/003 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 33/02 (20130101) F16B 33/006 (20130101) F16B 35/041 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174843 | Smallwood |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Drew L. Smallwood (Huntington Beach, California) |
| ABSTRACT | An example seal for use with a laminated window is described. The seal includes a first end formed from a first material and a second end formed from the first material, with the first material being compressible when a pressure force is applied to the first material. The seal also includes a connection portion positioned between the first end and the second end. At least some of the connection portion is formed from a second material having a greater indentation hardness than an indentation hardness of the first material. An example method for installing a seal is also described. |
| FILED | Tuesday, January 03, 2017 |
| APPL NO | 15/397671 |
| ART UNIT | 3638 — Static Structures, Supports and Furniture |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 3/5454 (20130101) E06B 7/22 (20130101) E06B 2003/5463 (20130101) Pistons; Cylinders; Sealings F16J 15/022 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175273 | Pulkkinen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Antti A. Pulkkinen (University Park, Maryland); Todd M. Bonalsky (Fords, New Jersey); Troy Ames (Laurel, Maryland); Carl F. Hostetter (Crofton, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Antti A. Pulkkinen (University Park, Maryland); Todd M. Bonalsky (Fords, New Jersey); Troy Ames (Laurel, Maryland); Carl F. Hostetter (Crofton, Maryland) |
| ABSTRACT | A high-voltage power transmission system is used as an extremely large antenna to extract spatiotemporal space, physical, and geological information from geomagnetically induced currents (GIC). A differential magnetometer method is used to measure GIC and involves acquiring line measurements from a first fluxgate magnetometer under a high-voltage transmission line, acquiring natural field measurements from a reference magnetometer nearby but not under the transmission line, subtracting the natural field measurements from the line measurements, and determining the GIC-related Biot-Savart field from the difference. NASA warning and alarm systems can be triggered based on determinations of GIC amplitude levels that exceed a set threshold value. |
| FILED | Wednesday, September 16, 2015 |
| APPL NO | 14/856090 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/165 (20130101) Original (OR) Class G01R 31/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10178499 | Regan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Curtis R. Regan (Norfolk, Virginia); Stephen J. Horan (Poquoson, Virginia) |
| ABSTRACT | Various embodiments may provide systems and methods for achieving continuous measurements (e.g., continuous video images) of the same spot on the Earth using Low Earth Orbit (LEO) satellite constellations and/or Middle Earth Orbit (MEO) satellite constellations. Various embodiments may provide a system of Virtual Low Earth Orbit (LEO) Stationary Satellites (VLSSs) over any area of the Earth for a continuous or a periodic amount of time. |
| FILED | Friday, April 20, 2018 |
| APPL NO | 15/958350 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/1021 (20130101) B64G 1/1085 (20130101) Electric Digital Data Processing G06F 17/30241 (20130101) Transmission H04B 7/1853 (20130101) Wireless Communication Networks H04W 4/021 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10174981 | Yashar |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland) |
| ASSIGNEE(S) | NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland) |
| INVENTOR(S) | David Yashar (Dunn Loring, Virginia) |
| ABSTRACT | A system to make ice includes a refrigeration unit and an icemaker disposed in the refrigeration unit. The refrigeration unit is configured to be subjected to a refrigeration cycle; the icemaker is configured to be subjected to a freeze cycle; and the system is configured such that the freeze cycle is synchronized with the refrigeration cycle, asynchronized with the refrigeration cycle, or a combination comprising at least one of the foregoing. A process for controlling an icemaker includes providing a freeze cycle to an icemaker; providing a refrigeration cycle to a refrigeration unit; and constraining the freeze cycle and the refrigeration cycle to control the icemaker. |
| FILED | Thursday, September 25, 2014 |
| APPL NO | 14/480708 |
| ART UNIT | 3744 — Static Structures, Supports and Furniture |
| CURRENT CPC | Producing, Working or Handling Ice F25C 1/00 (20130101) Original (OR) Class F25C 2600/04 (20130101) Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 29/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175150 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| INVENTOR(S) | Christopher M. Smith (Washington, District of Columbia); Matthew S. Hoehler (Poolesville, Maryland) |
| ABSTRACT | A resistance compensator includes: a first probe line to attach to a structural member and to provide a first combination of displacement of the structural member and an expansion of the first probe line; a second probe line connected to the first probe line and in electrical communication with the first probe line; a resistance probe in electrical communication with the first probe line and the second probe line to provide a probe signal, wherein the resistance probe is connected to the first probe line at a probe junction; a displacement member in mechanical communication with the first probe line, the displacement member to: receive the first combination from the first probe line; and produce a displacement signal comprising the displacement of the structural member, the expansion of the first probe line, or a combination thereof. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/375793 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 99/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177769 | Pan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Chenyun Pan (Atlanta, Georgia); Sourav Dutta (Atlanta, Georgia); Azad Naeemi (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present invention relate generally to logic devices, and more particularly, to magnetoelectric magnetic tunneling junction computational devices. Aspects of the disclosed technology include a stand-alone voltage-controlled magnetoelectric device that satisfies essential requirements for general logic applications, including nonlinearity, gain, concatenability, feedback prevention, and a complete set of Boolean operations based on the majority gate and inverter. Aspects of the present disclosed technology can eliminate the need for any auxiliary FETs to preset or complicated clocking schemes and prevents the racing condition. |
| FILED | Monday, April 23, 2018 |
| APPL NO | 15/959700 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/14 (20130101) H01F 10/16 (20130101) H01F 10/3218 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/22 (20130101) H01L 27/222 (20130101) H01L 43/02 (20130101) H01L 43/08 (20130101) H01L 43/10 (20130101) Pulse Technique H03K 19/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10173792 | Burckel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | David Bruce Burckel (Albuquerque, New Mexico) |
| ABSTRACT | A metallic waveguide tuned to an infrared region of interest provides spectral and spatial control over emitted/absorbed thermal radiation. The ratio of the depth of the waveguide to the smallest lateral dimension thereof is such that that the lateral dimension provides spectral selectivity and that the waveguide is deep enough for a fixed lateral dimension to establish directionality but is not so deep that it incurs severe ohmic losses. A panel with an array of such waveguides directs thermal radiation from a body in a specific direction and with a spectral response that is the result of the physical dimensions of the individual waveguides that make up the waveguide array and the arrangement of the waveguides in the array. The waveguide axis may be obliquely oriented with respect to the substrate normal so as to impart non-normal directionality to the emitted radiation with respect to the substrate normal surface. |
| FILED | Tuesday, November 24, 2015 |
| APPL NO | 14/950298 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/54 (20130101) B64G 1/58 (20130101) Original (OR) Class Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175491 | Gao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Magic Leap, Inc. (Plantation, Florida) |
| ASSIGNEE(S) | Magic Leap, Inc. (Plantation, Florida) |
| INVENTOR(S) | Chunyu Gao (Tucson, Arizona); Yuxiang Lin (Tucson, Arizona); Hong Hua (Tucson, Arizona) |
| ABSTRACT | The present invention comprises a compact optical see-through head-mounted display capable of combining, a see-through image path with a virtual image path such that the opaqueness of the see-through image path can be modulated and the virtual image occludes parts of the see-through image and vice versa. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/977593 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 13/06 (20130101) G02B 25/001 (20130101) G02B 27/144 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 27/283 (20130101) G02B 27/1066 (20130101) G02B 2027/015 (20130101) G02B 2027/0118 (20130101) G02B 2027/0145 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 37/02 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Pictorial Communication, e.g Television H04N 5/2258 (20130101) H04N 5/23238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10176408 | Paik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David S. Paik (Half Moon Bay, California); Andrew J. Buckler (Wenham, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts) |
| ASSIGNEE(S) | Elucid Bioimaging Inc. (Wenham, Massachusetts) |
| INVENTOR(S) | David S. Paik (Half Moon Bay, California); Andrew J. Buckler (Wenham, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Friday, December 04, 2015 |
| APPL NO | 14/959732 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00147 (20130101) G06K 9/6296 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10176431 | Yeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); The United States of America, as represented by the Director, National Security Agency (Washington, District of Columbia) |
| INVENTOR(S) | Jen-Hao Yeh (Arlington, Virginia); Benjamin S. Palmer (Silver Spring, Maryland); Frederick C. Wellstood (Fairfax, Virginia); Jay LeFebvre (Fairfield, Connecticut) |
| ABSTRACT | A dissipative device has a planar configuration with one or more resistor elements formed on an insulating substrate. Conductors are formed on the insulating substrate and are coupled to the resistor element(s) to transmit signals to/from the resistor element(s). The geometry of and materials for the dissipative device allow the conductors to act as heat sinks, which conduct heat generated in the resistor element(s) to the substrate (and on to a coupled housing) and cool hot electrons generated by the resistor element(s) via electron-phonon coupling. The dissipative device can be used in cooling a signal to a qubit, a cavity system of a quantum superconducting qubit, or any other cryogenic device sensitive to thermal noise. |
| FILED | Thursday, March 02, 2017 |
| APPL NO | 15/448284 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/227 (20130101) H01P 5/185 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10178041 | Dinan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | James Dinan (Hudson, Massachusetts); Mario Flajslik (Hudon, Massachusetts); David Keppel (Seattle, Washington); Ulf R. Hanebutte (Gig Harbor, Washington) |
| ABSTRACT | Technologies for aggregation-based message processing include multiple computing nodes in communication over a network. A computing node receives a message from a remote computing node, increments an event counter in response to receiving the message, determines whether an event trigger is satisfied in response to incrementing the counter, and writes a completion event to an event queue if the event trigger is satisfied. An application of the computing node monitors the event queue for the completion event. The application may be executed by a processor core of the computing node, and the other operations may be performed by a host fabric interface of the computing node. The computing node may be a target node and count one-sided messages received from an initiator node, or the computing node may be an initiator node and count acknowledgement messages received from a target node. Other embodiments are described and claimed. |
| FILED | Wednesday, September 23, 2015 |
| APPL NO | 14/862854 |
| ART UNIT | 2454 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/04 (20130101) H04L 43/16 (20130101) H04L 47/10 (20130101) H04L 47/30 (20130101) H04L 47/41 (20130101) H04L 47/62 (20130101) Original (OR) Class Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10174244 | Bourret-Courchesne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Edith D. Bourret-Courchesne (Berkeley, California); Gregory A. Bizarri (San Francisco, California) |
| ABSTRACT | The present invention provides for a composition comprising an inorganic scintillator comprising a doped halide, useful for detecting nuclear material. |
| FILED | Thursday, April 17, 2014 |
| APPL NO | 14/255697 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/628 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10172976 | Lancaster et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); The United States of America As Represented By The Department Of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Jordan J. Lancaster (Tucson, Arizona); Steven Goldman (Tucson, Arizona) |
| ABSTRACT | Disclosed herein are contractile cell constructs comprising contractile cells, or progenitors thereof, adhered to a surface of a three dimensional fibroblast containing scaffold (3DFCS) and methods for using them to treat disease. In one aspect, the present invention provides methods for preparing a contractile construct, comprising (a) seeding immature contractile cells onto the surface of a three dimensional fibroblast containing scaffold (3DFCS) to produce a contractile construct; and (b) culturing the contractile construct under conditions to promote differentiation of the immature contractile cells into mature contractile cells, wherein the mature contractile cells form striations. In a further aspect, the invention provides methods for treating a disorder characterized by a lack of functioning contractile cells, comprising contacting a patient with a contractile cell-based disorder with an amount effective to treat the disorder with the construct of any embodiment or combination of embodiments of the invention. |
| FILED | Wednesday, October 08, 2014 |
| APPL NO | 15/028606 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) A61K 38/18 (20130101) A61K 38/18 (20130101) A61K 38/2292 (20130101) A61K 38/2292 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/367 (20130101) A61L 27/3826 (20130101) Original (OR) Class A61L 27/3873 (20130101) A61L 2300/64 (20130101) A61L 2300/412 (20130101) A61L 2430/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0657 (20130101) C12N 2506/1315 (20130101) C12N 2513/00 (20130101) C12N 2527/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 10177287 | Melman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| ASSIGNEE(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| INVENTOR(S) | Jonathan Melman (Lexington, Kentucky); Robert Nordsell (Lexington, Kentucky); Kristen Baroudi (Lexington, Kentucky); Yong Bok Go (Lexington, Kentucky); Eric Bretschneider (Corinth, Texas); Alan C. Thomas (Yardley, Pennsylvania); Evan Thomas (Lexington, Kentucky) |
| ABSTRACT | Phosphors emitting green light over a narrow wavelength range may be used to broaden the gamut of display devices. In one aspect, a light emitting device comprises a light emitting solid state device emitting blue or violet light, a first phosphor that absorbs blue or violet light emitted by the light emitting solid state device and in response emits green light in a spectral band having a peak at wavelength λG and a height of one half its peak on a long wavelength edge of the band at wavelength λGhalf; and a second phosphor that absorbs blue or violet light emitted by the light emitting solid state device and in response emits red light in a spectral band having a peak at wavelength λR and a height of one half its peak on a short wavelength edge of the band at wavelength λRhalf. The ratio (λRhalf−λGhalf)/(λR−λG) is greater than 0.70. |
| FILED | Thursday, May 17, 2018 |
| APPL NO | 15/982193 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/56 (20130101) C09K 11/62 (20130101) C09K 11/64 (20130101) C09K 11/0838 (20130101) C09K 11/7728 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/504 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 10176438 | Shakarian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Tempe, Arizona); CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona); Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Paulo Shakarian (Chandler, Arizona); Eric Nunes (Tempe, Arizona); Casey Buto (Painted Post, New York); Christian Lebiere (Pittsburgh, Pennsylvania); Robert Thomson (Alexandria, Virginia); Stefano Bennati (Zurich, Switzerland) |
| ABSTRACT | Embodiments of a system and method for identifying malware tasks using a controlled environment to run malicious software to generate analysis reports, a parser to extract features from the analysis reports and a cognitively inspired learning algorithm to predict tasks associated with the malware are disclosed. |
| FILED | Friday, June 17, 2016 |
| APPL NO | 15/186278 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/552 (20130101) G06F 21/562 (20130101) Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10177287 | Melman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| ASSIGNEE(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| INVENTOR(S) | Jonathan Melman (Lexington, Kentucky); Robert Nordsell (Lexington, Kentucky); Kristen Baroudi (Lexington, Kentucky); Yong Bok Go (Lexington, Kentucky); Eric Bretschneider (Corinth, Texas); Alan C. Thomas (Yardley, Pennsylvania); Evan Thomas (Lexington, Kentucky) |
| ABSTRACT | Phosphors emitting green light over a narrow wavelength range may be used to broaden the gamut of display devices. In one aspect, a light emitting device comprises a light emitting solid state device emitting blue or violet light, a first phosphor that absorbs blue or violet light emitted by the light emitting solid state device and in response emits green light in a spectral band having a peak at wavelength λG and a height of one half its peak on a long wavelength edge of the band at wavelength λGhalf; and a second phosphor that absorbs blue or violet light emitted by the light emitting solid state device and in response emits red light in a spectral band having a peak at wavelength λR and a height of one half its peak on a short wavelength edge of the band at wavelength λRhalf. The ratio (λRhalf−λGhalf)/(λR−λG) is greater than 0.70. |
| FILED | Thursday, May 17, 2018 |
| APPL NO | 15/982193 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/56 (20130101) C09K 11/62 (20130101) C09K 11/64 (20130101) C09K 11/0838 (20130101) C09K 11/7728 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/504 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10173767 | Darrow, Jr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | David A. Darrow, Jr. (Stratford, Connecticut) |
| ABSTRACT | An aircraft is provided and includes a gearbox housing through which a drive shaft configured to drive propeller rotation extends and a pitch control apparatus. The pitch control apparatus includes a drive element coupled to an exterior of the gearbox housing and an annular electro-mechanical actuator (EMA) configured to convert rotational energy generated by the drive element to thereby control a pitching of propeller blades about corresponding pitch axes. |
| FILED | Thursday, June 26, 2014 |
| APPL NO | 14/915090 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 11/32 (20130101) B64C 11/44 (20130101) Original (OR) Class B64C 27/68 (20130101) B64C 27/82 (20130101) B64C 2027/8236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10174772 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Kirk A. Miller (Dallas, Texas); Mauricio A. Salinas (McKinney, Texas); Dustin Hamill (McKinney, Texas) |
| ABSTRACT | A device is provided for controlling fluid flow over a window of a movable optical instrument housing. The device includes a generally annular body having an inner peripheral edge configured to correspond to a peripheral edge of the window of the housing and an outer peripheral edge, an arcuate outer surface disposed between the inner peripheral edge and the outer peripheral edge, and a reduced width portion between the inner peripheral edge and the outer peripheral edge. The reduced width portion is configured to lower elevation torque. Other embodiments of the device and methods for controlling fluid flow are further disclosed. |
| FILED | Friday, December 16, 2016 |
| APPL NO | 15/381166 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/36 (20130101) B64C 1/1492 (20130101) B64C 7/00 (20130101) B64C 23/06 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 7/00 (20130101) B64D 47/08 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/003 (20130101) Original (OR) Class F15D 1/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10175348 | Clark et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRC, Inc. (North Syracuse, New York) |
| ASSIGNEE(S) | SRC, INC. (North Syracuse, New York) |
| INVENTOR(S) | Barry L. Clark (Manlius, New York); Andrew D. Keckler (Jamesville, New York); Thomas A. Houman (Jaffrey, New Hampshire) |
| ABSTRACT | A target is located and a track is associated with the target in the fusion coordinate system. An estimate/prediction of the target's velocity is developed within the tracker, as well as |
| FILED | Thursday, October 08, 2015 |
| APPL NO | 14/878558 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/42 (20130101) Original (OR) Class G01S 13/58 (20130101) G01S 13/87 (20130101) G01S 13/723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10177947 | Agee |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian G. Agee (San Jose, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian G. Agee (San Jose, California) |
| ABSTRACT | An apparatus and digital signal processing means are disclosed for excision of co-channel interference from signals received in crowded or hostile environments using spatial/polarization diverse arrays, which reliably and rapidly identifies signals with transmitted features that are almost-periodic over known framing intervals, and exploits those features to develop diversity combining weights that substantively extract those signals from that environment, based on differing diversity signature, timing offset, and carrier offset of those signals. In one embodiment, the signal identification and extraction is performed in an appliqué that can be implemented without coordination with an actual radio transceiver. |
| FILED | Monday, July 25, 2016 |
| APPL NO | 15/219145 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 7/0617 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/08 (20130101) Original (OR) Class H04L 27/264 (20130101) Wireless Communication Networks H04W 28/14 (20130101) H04W 52/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10178113 | Ciocarlie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gabriela F. Ciocarlie (New York, New York); Angelos Stavrou (Springfield, Virginia); Salvatore J. Stolfo (Ridgewood, New Jersey); Angelos D. Keromytis (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Gabriela F. Ciocarlie (New York, New York); Angelos Stavrou (Springfield, Virginia); Salvatore J. Stolfo (Ridgewood, New Jersey); Angelos D. Keromytis (New York, New York) |
| ABSTRACT | Systems, methods, and media for generating sanitized data, sanitizing anomaly detection models, and generating anomaly detection models are provided. In some embodiments, methods for sanitizing anomaly detection models are provided. The methods including: receiving at least one abnormal anomaly detection model from at least one remote location; comparing at least one of the at least one abnormal anomaly detection model to a local normal detection model to produce a common set of features common to both the at least one abnormal anomaly detection model and the local normal detection model; and generating a sanitized normal anomaly detection model by removing the common set of features from the local normal detection model. |
| FILED | Monday, July 13, 2015 |
| APPL NO | 14/798006 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/14 (20130101) H04L 63/1425 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, January 08, 2019.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190108.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page