FedInvent™ Patents

Patent Details for Tuesday, March 26, 2019

This page was updated on Monday, March 27, 2023 at 05:45 AM GMT

Department of Health and Human Services (HHS)

10238085 — Devices and methods for analyzing rodent behavior

US 10238085	Woolf et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD) NIH Office of the Director (NIHOD) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Clifford J. Woolf (Newton, Massachusetts); David P. Roberson (Cambridge, Massachusetts); Alexander B. Wiltschko (Brookline, Massachusetts); Sandeep Robert Datta (Newton, Massachusetts)
ABSTRACT	A device for detecting and recording animal behavior is provided. The device includes at least one corral that defines contained field, the base surface of the at least one corral being sensitive to the animal's footprint. The device also includes an image capturing device that cooperates with the base surface to capture both a profile of the animal's full footprint and a profile of the animal's toe print when the animal is standing on its toes. In some embodiments, the device is capable of providing a stimulus to the animal and observing the resulting behavior of the animal via the image capturing device.
FILED	Friday, October 31, 2014
APPL NO	15/032730
ART UNIT	3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 1/031 (20130101) Original (OR) Class A01K 29/005 (20130101) Diagnosis; Surgery; Identification A61B 5/1038 (20130101) A61B 5/1105 (20130101) A61B 5/1128 (20130101) Image Data Processing or Generation, in General G06T 7/20 (20130101)
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10238279 — Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope

US 10238279	Izatt et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Duke University (Durham, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Joseph A. Izatt (Durham, North Carolina); Liangbo Shen (Durham, North Carolina); Oscar M. Carrasco-Zevallos (Durham, North Carolina); Cynthia Toth (Durham, North Carolina)
ABSTRACT	Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope are disclosed herein. According to an aspect, a system includes first and second eyepieces. The system includes a display having first and second display portions, configured to display first images in the first display portion, and configured to display second images in the second display portion. The first image and the second image are projected along a first pathway and a second pathway. The system includes a first optical element positioned to relay the first images into the first eyepiece. The system includes a second optical element positioned to relay the second images into the second eyepiece.
FILED	Friday, February 05, 2016
APPL NO	15/547537
ART UNIT	2872 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/0041 (20130101) Original (OR) Class A61B 3/102 (20130101) A61B 3/132 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0012 (20130101) G02B 21/22 (20130101) G02B 27/0172 (20130101) G02B 2027/0134 (20130101) Pictorial Communication, e.g Television H04N 13/286 (20180501) H04N 13/293 (20180501) H04N 13/344 (20180501)
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10238329 — Apparatus, method and computer-accessible medium for diagnosing and subtyping psychiatric diseases

US 10238329	Bansal et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA) National Institute of Mental Health (NIMH)
APPLICANT(S)	Ravi Bansal (Cranbury, New Jersey); Bradley S. Peterson (Somers, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Ravi Bansal (Cranbury, New Jersey); Bradley S. Peterson (Somers, New York)
ABSTRACT	Exemplary method, system and computer-accessible medium can be provided for diagnosing at least one disease and/or a subtype within a disease. For example, it is possible to determine at least one region of interest, and obtain a plurality of data points associated with each of such region(s) of interest. It is also possible to identify a particular pattern of the data points across each of such region(s) of interest. Further, it is possible, e.g., using a computer arrangement, to determine a likelihood of the disease(s) and/or the subtype by comparing the particular pattern to at least one known pattern.
FILED	Friday, December 16, 2011
APPL NO	13/994925
ART UNIT	3737 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/165 (20130101) A61B 5/168 (20130101) A61B 5/0476 (20130101) A61B 5/726 (20130101) A61B 5/742 (20130101) A61B 5/04008 (20130101) A61B 5/4064 (20130101) Original (OR) Class A61B 5/4082 (20130101) A61B 5/7282 (20130101) A61B 6/032 (20130101) A61B 6/501 (20130101) A61B 6/5217 (20130101) A61B 8/0808 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/14 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 2209/05 (20130101)
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10238369 — Real time ultrasound thermal dose monitoring system for tumor ablation therapy

US 10238369	Guo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Xiaoyu Guo (Baltimore, Maryland); Emad M. Boctor (Baltimore, Maryland); Dengrong Jiang (Baltimore, Maryland)
ABSTRACT	An interventional system with real-time ablation thermal dose monitoring includes an interventional tool, an ultrasound transmitter at least one of attached to or integral with the interventional tool, an ultrasound receiver configured to receive ultrasound signals from the ultrasound transmitter after at least one of transmission through or reflection from a region of tissue while under an ablation procedure and to provide detection signals, and a signal processing system configured to communicate with the ultrasound receiver to receive the detection signals and to calculate, based on the detections signals, a thermal dose delivered to the region of tissue in real time during the ablation procedure.
FILED	Tuesday, June 10, 2014
APPL NO	14/301037
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0095 (20130101) A61B 8/085 (20130101) A61B 8/0841 (20130101) A61B 8/5223 (20130101) Original (OR) Class A61B 18/1492 (20130101) A61B 2018/263 (20130101) A61B 2018/00577 (20130101) A61B 2505/05 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) A61N 7/022 (20130101) A61N 2007/0004 (20130101) A61N 2007/0052 (20130101)
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10238370 — Steerable shape sensing biopsy needle

US 10238370	Park et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Medical Research Acquisition Activity (USAMRAA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) Small Business Administration (SBA) Small Business Innovation Research (SBIR) Small Business Technology Transfer (STTR)
APPLICANT(S)	Intelligent Fiber Optic Systems, Inc (Santa Clara, California)
ASSIGNEE(S)	INTELLIGENT FIBER OPTIC SYSTEMS, INC. (Santa Clara, California)
INVENTOR(S)	Yong-Lae Park (Stanford, California); Richard James Black (Menlo Park, California); Behzad Moslehi (Los Altos, California); Mark R. Cutkosky (Palo Alto, California); Santhi Elayaperumal (Stanford, California); Bruce Daniel (Stanford, California); Alan Yeung (Stanford, California); Vahid Sotoudeh (Los Altos, California)
ABSTRACT	A biopsy needle has a central axis and includes one or more sensing regions, each sensing region formed by a plurality of sensing optical fibers located over a particular extent of said central axis and inside the outer shell of the needle. The sensing optical fibers are coupled to a wavelength interrogator. A steerable catheter has a central axis and outer shell, the outer shell coupled to a plurality of optical fibers in sensing regions and actuation regions, the sensing regions formed over particular extents of the central axis by bonding gratings to the inner surface of the outer shell, and the actuation regions formed by coupling optical energy into shape memory alloys bonded to the outer shell.
FILED	Friday, January 03, 2014
APPL NO	14/147486
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 10/0266 (20130101) Original (OR) Class A61B 2017/003 (20130101) A61B 2017/00106 (20130101) A61B 2034/2061 (20160201) A61B 2090/065 (20160201)
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10238408 — Acoustic lens for shock wave lithotripsy and related methods

US 10238408	Zhong et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Pei Zhong (Chapel Hill, North Carolina); Glenn M. Preminger (Chapel Hill, North Carolina); Georgy N. Sankin (Durham, North Carolina); Franklin Hadley Cocks (Durham, North Carolina); Walter Neal Simmons (Durham, North Carolina)
ASSIGNEE(S)	DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S)	Pei Zhong (Chapel Hill, North Carolina); Glenn M. Preminger (Chapel Hill, North Carolina); Georgy N. Sankin (Durham, North Carolina); Franklin Hadley Cocks (Durham, North Carolina); Walter Neal Simmons (Durham, North Carolina)
ABSTRACT	Systems and methods for providing therapeutic shock waves are provided. A modified acoustic lens can include a first lens portion for directing a first part of an acoustic shock wave pulse toward a target and a second lens portion for directing a second part of the acoustic shock wave pulse toward the target. The second lens portion can be offset relative to the first portion such that transmission of the second part of the acoustic shock wave pulse through the second lens portion is delayed by a predetermined amount relative to transmission of the first part through the first lens portion. In situ superposition of the first and second pulses near and at the target can lead to the formation of a pressure waveform with idealized pulse profile and broadened focal width, which can provide for improved comminution of a concretion located within a living body with reduced tissue injury.
FILED	Monday, February 20, 2012
APPL NO	13/400446
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/225 (20130101) Original (OR) Class A61B 17/22004 (20130101)
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10238457 — System and method for endoscopic deployment of robotic concentric tube manipulators for performing surgery

US 10238457	Herrell et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	S. Duke Herrell (Nashville, Tennessee); Robert J. Webster, III (Nashville, Tennessee); Trevor Bruns (Nashville, Tennessee); Philip J. Swaney (Nashville, Tennessee); Richard Hendrick (Nasvhville, Tennessee)
ABSTRACT	An apparatus (20) for performing endoscopic surgery on a patient (12) includes at least two concentric tube manipulators (150) adapted to carry devices (152, 154) for performing a surgical operation. A transmission (200) operates the concentric tube manipulators (150). An endoscope tube (106) has a proximal end portion fixed to the transmission (200). The concentric tube manipulators (150) extend from the transmission (200) through an inner lumen (102) of the endoscope tube (106) and are operable to extend from a distal end (104) of the endoscope tube.
FILED	Friday, April 18, 2014
APPL NO	14/256540
ART UNIT	3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/0016 (20130101) A61B 1/00087 (20130101) A61B 1/00131 (20130101) A61B 1/00133 (20130101) A61B 1/303 (20130101) A61B 1/307 (20130101) A61B 18/22 (20130101) A61B 34/30 (20160201) Original (OR) Class A61B 34/70 (20160201) A61B 34/72 (20160201) A61B 34/74 (20160201) A61B 90/30 (20160201) A61B 90/361 (20160201) A61B 2034/301 (20160201) A61B 2034/742 (20160201)
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10238581 — Hyperbranched polyglycerol-coated particles and methods of making and using thereof

US 10238581	Deng et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Yale University (New Haven, Connecticut)
ASSIGNEE(S)	Yale University (New Haven, Connecticut)
INVENTOR(S)	Yang Deng (New Haven, Connecticut); Asiri Ediriwickrema (Cary, North Carolina); William M. Saltzman (New Haven, Connecticut)
ABSTRACT	Core-shell particles and methods of making and using thereof are described herein. The core is formed of or contains one or more hydrophobic materials or more hydrophobic materials. The shell is formed of or contains hyperbranched polyglycerol (HPG). The HPG coating can be modified to adjust the properties of the particles. Unmodified HPG coatings impart stealth properties to the particles which resist non-specific protein absorption and increase circulation in the blood. The hydroxyl groups on the HPG coating can be chemically modified to form functional groups that react with functional groups and adhere the particles to tissue, cells, or extracellular materials, such as proteins.
FILED	Monday, May 11, 2015
APPL NO	15/309741
ART UNIT	1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 8/90 (20130101) A61K 8/0241 (20130101) Original (OR) Class A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 9/1647 (20130101) A61K 9/5031 (20130101) A61K 9/5146 (20130101) A61K 9/5153 (20130101) A61K 31/427 (20130101) A61K 31/4178 (20130101) A61K 31/4745 (20130101) A61K 47/34 (20130101) A61K 2800/412 (20130101) A61K 2800/413 (20130101) A61K 2800/624 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/04 (20130101) Acyclic or Carbocyclic Compounds C07C 59/06 (20130101) C07C 59/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/005 (20130101)
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10238599 — Composition and method for treating congenital cytomegalovirus induced hearing loss

US 10238599	Miller et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Josef M. Miller (Ann Arbor, Michigan); Glenn E. Green (Dexter, Michigan); Barry Sheldon Seifer (Ann Arbor, Michigan); Albert Park (Salt Lake City, Utah); Ali Ahmed Almishaal (Alahsa-Hufof, Saudi Arabia); Phayvanh Phithaksounthone Sjogren (Salt Lake City, Utah)
ABSTRACT	A method of treating congenital cytomegalovirus (cCMV) induced hearing loss includes the step administering a composition to the mammal, wherein the composition consists essentially of a biologically effective amount of vitamin A, vitamin E, vitamin C, a vasodilator comprising magnesium, and, optionally, a withanolide, and/or resveratrol.
FILED	Monday, September 25, 2017
APPL NO	15/714445
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0046 (20130101) Original (OR) Class A61K 31/05 (20130101) A61K 31/07 (20130101) A61K 31/015 (20130101) A61K 31/58 (20130101) A61K 31/341 (20130101) A61K 31/355 (20130101) A61K 31/355 (20130101) A61K 31/375 (20130101) A61K 31/375 (20130101) A61K 31/585 (20130101) A61K 31/585 (20130101) A61K 33/00 (20130101) A61K 33/00 (20130101) A61K 33/06 (20130101) A61K 33/06 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) A61P 31/22 (20180101)
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10238610 — Retinoid replacements and opsin agonists and methods for the use thereof

US 10238610	Palczewski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	University of Washington (Seattle, Washington)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Krzysztof Palczewski (Bay Village, Ohio); David A. Saperstein (Seattle, Washington)
ABSTRACT	Compositions of and methods for using synthetic retinoids as retinoid replacements and opsin agonists are provided.
FILED	Friday, December 07, 2012
APPL NO	13/708558
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/07 (20130101) A61K 31/11 (20130101) Original (OR) Class A61K 31/382 (20130101) A61K 31/435 (20130101) A61K 31/695 (20130101) A61K 38/1709 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 514/912 (20130101)
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10238622 — Methods of treating and preventing/reducing the likelihood of Mesial temporal lobe epilepsy (TLE)

US 10238622	Mueller et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Alcohol Abuse and Alcoholism (NIAAA) National Research Service Award (NRSA)
APPLICANT(S)	Wolfgang S. Mueller (Albuquerque, New Mexico); John A. Connor (Albuquerque, New Mexico); Steven Peterson (Corpus Christi, Texas); Denis Bragin (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S)	Wolfgang S. Mueller (Albuquerque, New Mexico); John A. Connor (Albuquerque, New Mexico); Steven Peterson (Corpus Christi, Texas); Denis Bragin (Albuquerque, New Mexico)
ABSTRACT	The invention provides methods of treatment that prevent the onset of Mesial temporal lobe epilepsy (TLE) in a subject, or which reduce the severity of TLE in a subject, by administering a NKCC1 inhibitor to the subject after the subject has suffered from an insult known to precipitate TLE.
FILED	Friday, July 23, 2010
APPL NO	13/380921
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/34 (20130101) Original (OR) Class A61K 31/34 (20130101) A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/41 (20130101) A61K 31/41 (20130101) A61K 31/44 (20130101) A61K 31/44 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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10238626 — Therapeutic compounds

US 10238626	Wagner et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Carl E. Wagner (Glendale, Arizona); Pamela A. Marshall (Peoria, Arizona); Peter W. Jurutka (Scottsdale, Arizona)
ABSTRACT	The invention provides compounds of formula I: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers, Alzheimer's disease, and conditions associated with demyelination.
FILED	Tuesday, January 23, 2018
APPL NO	15/878291
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/352 (20130101) Original (OR) Class A61K 31/4433 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 35/00 (20180101)
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10238629 — Methods for reducing the occurrence of hot flashes

US 10238629	Sen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)	Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S)	Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S)	Chandan K. Sen (Upper Arlington, Ohio); Sashwati Roy (Upper Arlington, Ohio); Savita Khanna (Columbus, Ohio); Cameron Rink (Lewis Center, Ohio)
ABSTRACT	The present invention provides methods to reduce the number and severity of hot flashes utilizing tocotrienols. In particular, symptoms of perimenopause and menopause may be treated using the present methods. The present invention also provides methods to increase tissue concentrations of tocotrienols.
FILED	Tuesday, July 22, 2014
APPL NO	14/906695
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/107 (20130101) A61K 9/4858 (20130101) A61K 9/4866 (20130101) A61K 9/4875 (20130101) A61K 31/355 (20130101) Original (OR) Class A61K 31/355 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101)
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10238655 — Dihydroindene and tetrahydronaphthalene compounds

US 10238655	Wagner et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Carl E. Wagner (Glendale, Arizona); Pamela A. Marshall (Peoria, Arizona); Peter W. Jurutka (Scottsdale, Arizona)
ABSTRACT	The invention provides compounds of formula I: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers, Alzheimer's disease, and conditions associated with demyelination.
FILED	Tuesday, January 23, 2018
APPL NO	15/878297
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/10 (20130101) A61K 31/136 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) A61K 31/505 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 35/00 (20180101)
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10238663 — Extended-release drug delivery compositions

US 10238663	Dormer et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	ORBIS BIOSCIENCES, INC. (Lenexa, Kansas)
ASSIGNEE(S)	ORBIS BIOSCIENCES, INC. (Kansas City, Kansas)
INVENTOR(S)	Nathan Dormer (Mission, Kansas); Cory Berkland (Lawrence, Kansas)
ABSTRACT	An extended-release drug delivery composition and method of administering the same is provided. The composition comprises microspheres loaded with a biologically-active agent and suspended in a soluble polymer capable of forming a film upon injection onto a biological surface.
FILED	Friday, July 07, 2017
APPL NO	15/643857
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/10 (20130101) A61K 9/0019 (20130101) A61K 9/0046 (20130101) A61K 9/1635 (20130101) A61K 9/1647 (20130101) A61K 31/43 (20130101) A61K 31/573 (20130101) Original (OR) Class A61K 31/711 (20130101) A61K 31/713 (20130101) A61K 38/38 (20130101) A61K 47/10 (20130101) A61K 47/26 (20130101) A61K 47/32 (20130101) A61K 47/38 (20130101)
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10238667 — Vitamin D receptor/SMAD genomic circuit gates fibrotic response

US 10238667	Ding et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S)	Salk Institute for Biological Studies (La Jolla, California); The University of Sydney (Sydney, Australia)
ASSIGNEE(S)	Salk Institute for Biological Studies (La Jolla, California); The University of Sydney (Sydney, Australia)
INVENTOR(S)	Ning Ding (Riverside, California); Michael Downes (San Diego, California); Christopher Liddle (Tura Beach, Australia); Ronald M. Evans (La Jolla, California); Nanthakumar Subramaniam (Wentworthville, Australia)
ABSTRACT	The present disclosure provides compositions that include a nanoparticle and a compound that increases the biological activity of the vitamin D receptor (VDR) (e.g., a VDR agonist), and methods of using such compounds to increase retention or storage of vitamin A, vitamin D, and/or lipids by a cell, such as an epithelial or stellate cell. Such methods can be used to treat or prevent fibrosis.
FILED	Wednesday, November 08, 2017
APPL NO	15/807424
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/167 (20130101) A61K 31/07 (20130101) A61K 31/07 (20130101) A61K 31/59 (20130101) A61K 31/59 (20130101) A61K 31/592 (20130101) Original (OR) Class A61K 31/592 (20130101) A61K 31/593 (20130101) A61K 31/593 (20130101) A61K 31/7068 (20130101) A61K 31/7068 (20130101) A61K 45/06 (20130101) A61K 47/62 (20170801) A61K 47/542 (20170801) A61K 47/6929 (20170801) A61K 47/6931 (20170801) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/82 (20130101) G01N 33/5058 (20130101) G01N 2500/10 (20130101) G01N 2800/085 (20130101)
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10238669 — Methods and materials for treating calcific aortic valve stenosis

US 10238669	Miller et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S)	Jordan D. Miller (Rochester, Minnesota); Bin Zhang (Rochester, Minnesota)
ABSTRACT	This document provides methods and materials involved in treating cardiovascular conditions such as calcific aortic valve stenosis. For example, methods and materials for using sGC agonists or a combination of sGC agonists and PDE5A inhibitors to reduce calcification of heart valves and/or vessels or to slow progression of aortic sclerosis to calcific aortic valve stenosis are provided.
FILED	Tuesday, September 12, 2017
APPL NO	15/702461
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/197 (20130101) A61K 31/197 (20130101) A61K 31/416 (20130101) A61K 31/416 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/635 (20130101) Original (OR) Class A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 31/5377 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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10238699 — Tropic cell based virotherapy for the treatment of cancer

US 10238699	Aboody et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	CITY OF HOPE (Duarte, California); UNIVERSITY OF CHICAGO (Chicago, Illinois); UNIVERSITY OF ALABAMA at BIRMINGHAM (Birmingham, Alabama)
ASSIGNEE(S)	CITY OF HOPE (Duarte, California); UNIVERSITY OF CHICAGO (Chicago, Illinois); UNIVERSITY OF ALABAMA AT BIRMINGHAM (Birmingham, Alabama)
INVENTOR(S)	Karen S. Aboody (Arcadia, California); Alexander J. Annala (Arcadia, California); David Curiel (St. Louis, Missouri); Maciej Lesniak (Chicago, Illinois)
ABSTRACT	In some embodiments, methods of killing tumor cells are provided. The methods may include contacting the tumor cell with a tropic cell that carries a modified oncolytic virus, wherein the virus comprises a tumor selective element and/or a capsid protein that binds a tumor-specific cell surface molecule. In another embodiment, methods of treating cancer are provided. The methods may include administering a therapeutically effective amount of a pharmaceutical composition to a subject, wherein the pharmaceutical composition includes a tropic cell that carries a modified oncolytic virus, wherein the virus comprises a tumor selective promoter element and/or a capsid protein that binds a tumor-specific cell surface molecule.
FILED	Friday, September 11, 2015
APPL NO	14/852378
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) A61K 35/545 (20130101) A61K 35/761 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10332 (20130101)
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10238734 — Compositions and methods for self-adjuvanting vaccines against microbes and tumors

US 10238734	Kornbluth et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Richard Syd Kornbluth (La Jolla, California); Geoffrey William Stone (Coral Gables, Florida)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Richard Syd Kornbluth (La Jolla, California); Geoffrey William Stone (Coral Gables, Florida)
ABSTRACT	The present invention is drawn to compositions and methods to enhance an immune response in order to prevent or treat infections or hyperproliferative diseases such as cancer. More particularly, the composition is an immunostimulatory intracellular signaling peptide fused directly or indirectly to a peptide that leads to multimerization into complexes of three or more units, where the intracelluar signaling peptide must be present in a complex of three or more units in order to stimulate an immune response. Inserting this fusion construct into viruses like HIV-1 or introducing it into dendritic cells or tumor cells is predicted to lead to a positive therapeutic effect in humans, non-human mammals, birds, and fish.
FILED	Tuesday, March 22, 2011
APPL NO	13/635885
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/763 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/5256 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/005 (20130101) C07K 14/70578 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/16222 (20130101) C12N 2710/16632 (20130101) C12N 2710/24143 (20130101) C12N 2740/15011 (20130101) C12N 2740/16011 (20130101)
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10238741 — Nucleic acid constructs for presentation of CD4 and CD8 epitopes, cellular transfection and uses thereof

US 10238741	Creusot
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Remi J. Creusot (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Remi J. Creusot (New York, New York)
ABSTRACT	The invention relates to constructs, cells and methods for modulating the immune system that optimize presentation of CD4 and CD8 epitopes to antigen-presenting cells and transfection into cells. Epitopes to either self antigens or non-self antigens can be used to optimize either a tolerance or immunogenicity to those epitopes, respectively. Certain new constructs encode one or more dominant, disease-driving epitopes (CD4) targeted for MHCII processing within the endosomes of a cell and one or more epitopes (CD8) targeted for MHCI processing within the cytosol of the cell, to produce the maximum antigen/epitope presentation in the immune system, and further include an MHCII activator sequence. Alternatively, the new constructs encode CD4 and CD8 epitopes operably linked to a secretion signal.
FILED	Monday, April 10, 2017
APPL NO	15/483889
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 35/76 (20130101) A61K 39/00 (20130101) A61K 39/42 (20130101) Original (OR) Class Peptides C07K 14/55 (20130101) C07K 14/575 (20130101) C07K 14/70535 (20130101) C07K 14/70582 (20130101) C07K 2319/01 (20130101) C07K 2319/50 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/88 (20130101)
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10238750 — Porphyrin modified telodendrimers

US 10238750	Lam et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Kit Lam (Davis, California); Yuanpei Li (Elk Grove, California); Chongxian Pan (Davis, California)
ABSTRACT	The present invention provides amphiphilic telodendrimers that aggregate to form nanocarriers characterized by a hydrophobic core and a hydrophilic exterior. The nanocarrier core may include amphiphilic functionality such as cholic acid or cholic acid derivatives, and the exterior may include branched or linear poly(ethylene glycol) segments. Nanocarrier cargo such as hydrophobic drugs and other materials may be sequester in the core via non-covalent means or may be covalently bound to the telodendrimer building blocks. Telodendrimer structure may be tailored to alter loading properties, interactions with materials such as biological membranes, and other characteristics.
FILED	Thursday, December 12, 2013
APPL NO	14/651860
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 41/0033 (20130101) A61K 41/0052 (20130101) A61K 41/0071 (20130101) A61K 41/0076 (20130101) A61K 47/60 (20170801) Original (OR) Class A61K 47/62 (20170801) A61K 47/6907 (20170801) A61K 47/6911 (20170801) A61K 49/0002 (20130101) A61K 49/0036 (20130101) A61K 49/0082 (20130101) A61K 49/0423 (20130101) A61K 49/1809 (20130101) A61K 51/1227 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101)
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10238755 — Methods and compositions for regulation of cell aging, carcinogenesis and reprogramming

US 10238755	Maul et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Center for Research Resources (NCRR) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania)
INVENTOR(S)	Gerd G. Maul (Wynnewood, Pennsylvania); Dmitri G. Negorev (West Chester, Pennsylvania); Louise C. Showe (Media, Pennsylvania); Olga V. Vladimirova (Philadelphia, Pennsylvania)
ABSTRACT	Compositions and methods described herein include somatic cells that are competent for reprogramming and malignant transformation and are characterized by a reduction of the levels of Sp100 in the cells, cells having markers of pluripotent stem cells, and methods for preparing same. Methods for reversably regulating aging or reprogramming to pluripotency in a somatic cell involve modulating the expression of Sp100 therein. Methods and compositions for retarding the growth of or suppressing unwanted cell proliferation involve expressing, inducing expression of, or upregulating, Sp100 in a targeted cell that is undergoing unrestricted proliferation or replication or increasing exposure to Sp100 in the environment or microenvironment of the targeted cell. Also disclosed are methods for treating a proliferative disease or condition by increasing expression or levels of Sp100 in the targeted cell or its environment.
FILED	Thursday, November 29, 2012
APPL NO	14/361970
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/545 (20130101) A61K 48/005 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0656 (20130101) C12N 5/0696 (20130101) C12N 15/63 (20130101) C12N 15/113 (20130101) C12N 2501/998 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101) C12N 2510/04 (20130101) C12N 2740/15041 (20130101)
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10238756 — Lipid nanoparticles and uses thereof

US 10238756	Ho et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Tongli Biomedical Co., Ltd. (Suzhou, China PRC)
ASSIGNEE(S)	Tongli Biomedical Co., Ltd. (Suzhou, China PRC)
INVENTOR(S)	Rodney J. Y. Ho (Mercer Island, Washington); John C. Kraft, II (Seattle, Washington); Mingxin Qian (Suzhou, China PRC)
ABSTRACT	The present invention relates to lipid-associated indocyanine green particles for enhanced functional high-resolution near-infrared fluorescence medical imaging of lymphatic vessels, lymph nodes, lymphatic abnormalities, tumors, and inflammation.
FILED	Friday, May 29, 2015
APPL NO	14/725178
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0034 (20130101) A61K 49/0052 (20130101) Original (OR) Class A61K 49/0082 (20130101)
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10238757 — Methods and compositions for detection of cancer

US 10238757	Brady-Kalnay
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Susann Brady-Kalnay (Cleveland, Ohio)
ABSTRACT	A molecular probe for use in detection of cancer cells expressing an Ig superfamily cell adhesion molecule that binds in a homophilic fashion in a subject includes a targeting agent that specifically binds to and/or complexes with a proteolytically cleaved extracellular fragment of the Ig superfamily cell adhesion molecule.
FILED	Monday, February 24, 2014
APPL NO	14/188404
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0058 (20130101) Original (OR) Class A61K 51/088 (20130101) Peptides C07K 16/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 2333/70503 (20130101)
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10238758 — Radiolabeled alpha-melanocyte stimulating hormone hybrid peptide for melanoma targeting

US 10238758	Miao
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Institute of General Medical Sciences (NIGMS) IDeA Networks of Biomedical Research Excellence (INBRE)
APPLICANT(S)	STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Yubin Miao (Englewood, Colorado)
ABSTRACT	The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue, suggesting favorable selective activity of compounds according to the present invention, which can be used as effective therapeutic agents against melanoma, including metastatic melanoma. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are useful to initiate therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic and therapeutic tools for a number of conditions and diseases states, especially melanoma.
FILED	Saturday, September 10, 2016
APPL NO	15/261890
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/17 (20130101) A61K 51/082 (20130101) A61K 51/086 (20130101) Original (OR) Class Peptides C07K 7/56 (20130101)
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10238767 — Mono-layer thin film adhesive compounds and methods of synthesis and use

US 10238767	Murphy et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	DSM IP ASSETS B.V. (TE HEERLEN, Netherlands)
ASSIGNEE(S)	DSM IP ASSETS, B.V. (Heerlen, Netherlands)
INVENTOR(S)	John L. Murphy (Madison, Wisconsin); Jeffrey L. Dalsin (Verona, Wisconsin); Arinne N. Lyman (Neenah, Wisconsin); Laura L. Bremer (Lodi, Wisconsin); Joel L. Broussard (Madison, Wisconsin); Neil Winterbottom (San Mateo, California); Justin T. Koepsel (Madison, Wisconsin)
ABSTRACT	The invention relates provides synthetic medical adhesives which exploit plant derivatives to form covalent bonds with amines and thiols on tissue surfaces.
FILED	Thursday, July 25, 2013
APPL NO	13/951182
ART UNIT	1787 — Miscellaneous Articles, Stock Material
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/00 (20130101) A61L 24/001 (20130101) A61L 24/04 (20130101) A61L 24/046 (20130101) Original (OR) Class A61L 27/34 (20130101) A61L 27/50 (20130101) A61L 31/10 (20130101) A61L 31/14 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/12 (20130101) B32B 27/08 (20130101) B32B 27/12 (20130101) B32B 27/18 (20130101) B32B 27/26 (20130101) B32B 27/28 (20130101) B32B 27/34 (20130101) B32B 27/36 (20130101) B32B 27/40 (20130101) B32B 27/285 (20130101) B32B 2250/02 (20130101) B32B 2250/03 (20130101) B32B 2255/02 (20130101) B32B 2255/26 (20130101) B32B 2255/28 (20130101) B32B 2405/00 (20130101) B32B 2535/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/00 (20130101) C08G 63/06 (20130101) C08G 63/08 (20130101) C08G 63/66 (20130101) C08G 63/68 (20130101) C08G 63/91 (20130101) C08G 63/664 (20130101) C08G 63/685 (20130101) C08G 63/912 (20130101) C08G 63/6852 (20130101) C08G 64/00 (20130101) C08G 65/00 (20130101) C08G 69/00 (20130101) C08G 69/40 (20130101) C08G 69/44 (20130101) C08G 69/48 (20130101) C08G 71/00 (20130101) C08G 73/02 (20130101) C08G 73/024 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/04 (20130101) C08K 5/17 (20130101) C08K 5/19 (20130101) Compositions of Macromolecular Compounds C08L 67/00 (20130101) C08L 67/04 (20130101) C08L 69/00 (20130101) C08L 71/00 (20130101) C08L 75/02 (20130101) C08L 75/04 (20130101) C08L 77/00 (20130101) C08L 77/12 (20130101) C08L 79/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 167/00 (20130101) C09D 167/04 (20130101) C09D 169/00 (20130101) C09D 171/00 (20130101) C09D 175/02 (20130101) C09D 175/04 (20130101) C09D 177/00 (20130101) C09D 177/12 (20130101) C09D 179/02 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 5/02 (20130101) C09J 11/06 (20130101) C09J 167/00 (20130101) C09J 167/04 (20130101) C09J 169/00 (20130101) C09J 171/00 (20130101) C09J 175/02 (20130101) C09J 175/04 (20130101) C09J 177/00 (20130101) C09J 177/12 (20130101) C09J 179/02 (20130101) C09J 2203/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2848 (20150115) Y10T 428/2852 (20150115) Y10T 428/31536 (20150401) Y10T 428/31551 (20150401) Y10T 428/31558 (20150401) Y10T 428/31725 (20150401) Y10T 428/31786 (20150401) Y10T 428/31794 (20150401) Y10T 442/10 (20150401) Y10T 442/2738 (20150401)
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10239830 — Benzenesulfonamide upregulators of NPC1 for Neimann-Pick disease and other lysosomal storage disorders

US 10239830	Patnaik et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Institute of Mental Health (NIMH)
APPLICANT(S)	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York); The United States of America, as represented by the Secretary, Depart. of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Samarjit Patnaik (Rockville, Maryland); Mercedes Taylor (Berkeley, California); Raul Rolando Calvo (Rockville, Maryland); Juan Jose Marugan (Rockville, Maryland); Noel Southall (Rockville, Maryland); Wei Zheng (Rockville, Maryland); Marc Ferrer-Alegre (Rockville, Maryland); Seameen Dehdasthi (Rockville, Maryland); Patricia Dranchak (Rockville, Maryland); Fannie Chen (New York, New York); Yiannis Ioannou (New York, New York)
ABSTRACT	Methods and compositions for treating lysosomal storage disorders are disclosed. The methods involve administering a genus of benzenesulfonamides, particularly N-[3-(aminosulfonyl)phenyl]-benzamides and heteroarylamides. A genus of suitable compounds is shown in formula 1:
FILED	Thursday, February 11, 2016
APPL NO	15/549743
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/165 (20130101) A61K 31/4164 (20130101) Acyclic or Carbocyclic Compounds C07C 311/21 (20130101) Original (OR) Class Heterocyclic Compounds C07D 207/335 (20130101) C07D 213/46 (20130101) C07D 233/64 (20130101)
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10239834 — Antibiotic sensitivity-restoring and photosensitive agents

US 10239834	Rogelj et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION (Socorro, New Mexico)
ASSIGNEE(S)	NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION (Socorro, New Mexico)
INVENTOR(S)	Snezna Rogelj (Socorro, New Mexico); Liliya Frolova (Socorro, New Mexico); Alexander Kornienko (San Marcos, Texas); Leslie D. Edwards (Socorro, New Mexico); Cody Champion (Las Cruces, New Mexico); Kailee Zingler (Tomah, Wisconsin); Danielle Nicole Turner (Socorro, New Mexico)
ABSTRACT	The present disclosure describes a method to treat conditions, including bacterial infections and cancer, using a photosensitive compound that, upon exposure to white light, can be activated. The photosensitive compound can also interact synergistically with antibiotics used concomitantly to kill drug-resistant bacteria. The photosensitive compounds can also be used to inhibit the proliferation of cancer cells.
FILED	Tuesday, October 31, 2017
APPL NO	15/798545
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/65 (20130101) A61K 31/404 (20130101) A61K 31/431 (20130101) A61K 31/496 (20130101) A61K 31/655 (20130101) A61K 31/7036 (20130101) A61K 31/7048 (20130101) A61K 38/12 (20130101) A61K 38/12 (20130101) A61K 38/14 (20130101) A61K 38/14 (20130101) A61K 41/0057 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 209/10 (20130101) C07D 209/30 (20130101) C07D 209/36 (20130101) C07D 209/40 (20130101) C07D 209/42 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/473 (20180101)
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10239850 — 14-hydroxy-docosahexaenoic acid compounds

US 10239850	Serhan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Brigham And Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Charles N. Serhan (Needham, Massachusetts); Rong Yang (Boston, Massachusetts)
ABSTRACT	The invention describes novel 14-hydroxy docosahexaenoic acid (DHA) analogs, their preparation, isolation, identification, purification and uses thereof.
FILED	Monday, February 20, 2017
APPL NO	15/437206
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Fodder A23K 20/158 (20160501) Preparations for Medical, Dental, or Toilet Purposes A61K 8/37 (20130101) A61K 8/365 (20130101) A61K 8/4973 (20130101) A61K 31/202 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 5/006 (20130101) A61Q 19/00 (20130101) A61Q 19/08 (20130101) Acyclic or Carbocyclic Compounds C07C 59/42 (20130101) C07C 59/58 (20130101) C07C 69/732 (20130101) Heterocyclic Compounds C07D 303/12 (20130101) C07D 303/38 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/55 (20151101)
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10239868 — 5-hydroxytryptamine receptor 7 activity modulators and their method of use

US 10239868	Canney et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania)
ASSIGNEE(S)	TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania)
INVENTOR(S)	Daniel J. Canney (Ambler, Pennsylvania); Benjamin E. Blass (Eagleville, Pennsylvania); Rong Gao (Eugene, Oregon); Magid Abou-Gharbia (Exton, Pennsylvania)
ABSTRACT	Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
FILED	Wednesday, September 27, 2017
APPL NO	15/716752
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 307/33 (20130101) C07D 307/94 (20130101) C07D 405/06 (20130101) C07D 405/12 (20130101) Original (OR) Class
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10239877 — Pharmacophore for trail induction

US 10239877	Janda et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S)	The Scripps Research Institute (La Jolla, California)
INVENTOR(S)	Kim D. Janda (La Jolla, California); Nicholas T. Jacob (San Diego, California); Jonathan W. Lockner (San Diego, California)
ABSTRACT	There are disclosed imidazolinopyrimidinone compounds that have activity to induce TRAIL gene expression in macrophages. There is further disclosed a method for treating various cancers comprising administering effective amounts of an imidazolinopyrimidinone having the structure of Formula I herein. The invention is directed, in various embodiments, to a compound and pharmaceutical composition comprising an effective amount of a compound capable of inducing expression of TRAIL gene in cells capable of expressing the TRAIL gene to produce the cytokine TRAIL.
FILED	Monday, March 30, 2015
APPL NO	15/126192
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Heterocyclic Compounds C07D 471/14 (20130101) Original (OR) Class
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10239880 — Cyclopenta[d]pyrimidines and substituted cyclopenta[d]pyrimidines as antitubulin and microtubule targeting agents, monocyclic pyrimidines as tubulin inhibitors, and pyrrolopyrimidines as targeted antifolates and tubulin and multiple receptor tyrosine kinase inhibition and antitumor agents

US 10239880	Gangjee
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania)
INVENTOR(S)	Aleem Gangjee (Allison Park, Pennsylvania)
ABSTRACT	The present invention provides a compound of Formula I, and salts thereof, and a pharmaceutical composition comprising a compound of Formula I: wherein R₁is selected from the group consisting of and R₂is an alkyl group having from one to ten carbon atoms, or wherein R₂is selected from the group consisting of R₁is an alkyl group having from one to ten carbon atoms; and R is H, or an alkyl group having from one to ten carbon atoms, and R₃is H, an alkyl group having from one to ten carbon atoms, or a halogen. Preferably the compound of Formula V includes wherein R₃is a halogen, and most preferably wherein the halogen is chlorine. Methods of treating a patient with cancer with these compounds are also provided.
FILED	Friday, April 15, 2016
APPL NO	15/130219
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 239/94 (20130101) C07D 487/04 (20130101) Original (OR) Class
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10239887 — Positive allosteric modulators of the muscarinic acetylcholine receptor M4

US 10239887	Lindsley et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Craig W. Lindsley (Brentwood, Tennessee); P. Jeffrey Conn (Nashville, Tennessee); Darren W. Engers (Brentwood, Tennessee); Sean Bollinger (Murfreesboro, Tennessee); James C. Tarr (Franklin, Tennessee); Paul Spearing (Chapel Hill, Tennessee); Julie L. Engers (Brentwood, Tennessee); Madeline Long (Nashville, Tennessee); Thomas M. Bridges (Nashville, Tennessee)
ABSTRACT	Disclosed herein are tricyclic compounds, including pyrimido[4′,5′:4,5]thieno[2,3-c]pyridazine-8-amine, pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine-4-amine, pyrazino[2′,3′:4,5]thieno[3,2-d]pyrimidin-4-amine, pyrido[3′,2′:4,5]furo[3,2-d]pyrimidin-4-amine, and pyrimido[4′,5′:4,5]furo[2,3-c]pyridazin-8-amine compounds, which may be useful as positive allosteric modulators of the muscarinic acetylcholine receptor M₄(mAChR M₄). Also disclosed herein are methods of making the compounds, pharmaceutical compositions comprising the compounds, and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions.
FILED	Thursday, June 22, 2017
APPL NO	15/630200
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 493/14 (20130101) C07D 495/14 (20130101) Original (OR) Class C07D 519/00 (20130101)
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10239918 — Cahuitamycins and methods of making and using the same

US 10239918	Sherman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) Fogarty International Center (FIC) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	David H. Sherman (Ann Arbor, Michigan); Fengan Yu (Ann Arbor, Michigan); Chuanwu Xi (Ann Arbor, Michigan); Jianfeng Wu (Ann Arbor, Michigan); Pamela J. Schultz (Superior Township, Michigan); Ashootosh Tripathi (Ypsilanti, Michigan); Sung Ryeol Park (Ann Arbor, Michigan)
ABSTRACT	Provided herein are biofilm inhibitors obtained from marine microbial derived natural product extracts from Streptomyces gandocaensis, resulting in biofilm inhibitors, cahuitamycins. Also provided are mutant S. gandocaensis, methods of inhibiting biofilm formation, methods of producing, or increasing the production of, cahuitamycins, methods for synthesizing cahuitamycins, and methods of purifying cahuitamycins.
FILED	Thursday, May 26, 2016
APPL NO	15/576494
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) A01N 43/76 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/07 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 413/12 (20130101) Peptides C07K 5/00 (20130101) C07K 5/081 (20130101) C07K 5/1013 (20130101) C07K 7/06 (20130101) Original (OR) Class C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Enzymes C12Y 402/99021 (20130101)
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10239920 — Cupredoxin derived transport agents and methods of use thereof

US 10239920	Chakrabarty et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S)	Ananda Chakrabarty (Villa Park, Illinois); Tapas Das Gupta (River Forest, Illinois); Tohru Yamada (Oak Park, Illinois); Arsenio Fialho (Lisbon, Portugal)
ABSTRACT	The present invention discloses methods and materials for delivering a cargo compound into a cancer cell. Delivery of the cargo compound is accomplished by the use of protein transduction domains derived from cupredoxins. The invention further discloses methods for treating cancer and diagnosing cancer.
FILED	Monday, October 19, 2015
APPL NO	14/887100
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/13 (20130101) A61K 38/00 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/164 (20130101) A61K 45/06 (20130101) A61K 49/00 (20130101) A61K 49/04 (20130101) A61K 49/14 (20130101) A61K 49/221 (20130101) Peptides C07K 14/21 (20130101) C07K 14/22 (20130101) C07K 14/28 (20130101) Original (OR) Class C07K 14/195 (20130101) C07K 14/235 (20130101) C07K 2319/02 (20130101)
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10239926 — Compositions and methods for vascular protection against reperfusion injury after myocardial ischemia

US 10239926	Spees
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The University of Vermont and State Agriculture College (Burlington, Vermont)
ASSIGNEE(S)	The University of Vermont and State Agriculture College (Burlington, Vermont)
INVENTOR(S)	Jeffrey Spees (Burlington, Vermont)
ABSTRACT	As described herein, the present invention features compositions comprising an HGF/IgG complex and methods of using such compositions to reduce ischemic reperfusion injury.
FILED	Tuesday, February 23, 2016
APPL NO	15/553505
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/18 (20130101) Peptides C07K 14/47 (20130101) C07K 14/475 (20130101) Original (OR) Class C07K 14/70503 (20130101)
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10239933 — Compositions and methods for modulating thrombin generation

US 10239933	Camire et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania)
INVENTOR(S)	Rodney M. Camire (Sicklerville, New Jersey); Matthew W. Bunce (Havertown, Pennsylvania); Mettine H. A. Bos (Amsterdam, Netherlands)
ABSTRACT	Factor V peptides and methods of use thereof are disclosed.
FILED	Monday, April 18, 2016
APPL NO	15/131385
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/36 (20130101) A61K 45/06 (20130101) Peptides C07K 14/745 (20130101) Original (OR) Class C07K 2319/35 (20130101)
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10239934 — Monoclonal antibodies directed against trimeric forms of the HIV-1 envelope glycoprotein with broad and potent neutralizing activity

US 10239934	Chan-Hui et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Theraclone Sciences, Inc. (Seattle, Washington); International AIDS Vaccine Initiative (New York, New York); The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S)	Theraclone Sciences, Inc. (Seattle, Washington); International AIDS Vaccine Initiative (New York, New York); The Scripps Research Institute (La Jolla, California)
INVENTOR(S)	Po-Ying Chan-Hui (Bellevue, Washington); Steven Frey (Redmond, Washington); Ole Olsen (Everett, Washington); Jennifer Mitcham (Redmond, Washington); Matthew Moyle (Redmond, Washington); Sanjay K. Phogat (Frederick, Maryland); Dennis R. Burton (La Jolla, California); Laura Marjorie Walker (San Diego, California); Pascal Raymond Georges Poignard (San Diego, California); Wayne Koff (Stony Brook, New York); Melissa Danielle De Jean De St. Marcel Simek-Lemos (Brooklyn, New York); Stephen Kaminsky (Bronx, New York)
ABSTRACT	The invention provides a method for obtaining a broadly neutralizing antibody (bNab), including screening memory B cell cultures from a donor PBMC sample for neutralization activity against a plurality of HIV-1 species, cloning a memory B cell that exhibits broad neutralization activity; and rescuing a monoclonal antibody from that memory B cell culture. The resultant monoclonal antibodies are characterized by their ability to selectively bind epitopes from the Env proteins in native or monomeric form, as well as to inhibit infection of HIV-1 species from a plurality of clades. Compositions containing human monoclonal anti-HIV antibodies used for prophylaxis, diagnosis and treatment of HIV infection are provided. Methods for generating such antibodies by immunization using epitopes from conserved regions within the variable loops of gp120 are provided. Immunogens for generating anti-HIV1 bNAbs are also provided. Furthermore, methods for vaccination using suitable epitopes are provided.
FILED	Monday, March 12, 2018
APPL NO	15/918343
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/1045 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101)
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10239952 — Anti-WT1/HLA bi-specific antibody

US 10239952	Scheinberg et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); EUREKA THERAPEUTICS, INC. (Emeryville, California)
ASSIGNEE(S)	Memorial Sloan Kettering Cancer Center (New York, New York); Eureka Therapeutics, Inc. (Emeryville, California)
INVENTOR(S)	David Scheinberg (New York, New York); Jingyi Xiang (Walnut Creek, California); Tao Dao (New York, New York); Su Yan (State College, Pennsylvania); Cheng Liu (Oakland, California)
ABSTRACT	Disclosed herein is a bi-specific form of a T cell receptor mimic (TCRm) mAb with reactivity to human immune effector cell antigen and a WT1 peptide/HLA-A epitope. This antibody selectively bound to leukemias and solid tumor cells expressing WT1 and HLA-A as well as activated resting human T cells to release interferon-(IFN-γ) and to kill the target cancer cells in vitro. Importantly, the antibody mediated autologous T cell proliferation and directed potent cytotoxicity against fresh ovarian cancer cells. Therapeutic activity in vivo of the antibody was demonstrated in NOD SCID SCID Yc*(NSG) mice with three different human cancers expressing WT1/HLA-A2 including disseminated Ph+ acute lymphocytic leukemia (ALL), disseminated acute myeloid leukemia, and peritoneal mesothelioma. In both of the leukemia xenograft models, mice that received the antibody and T cells also showed longer survival and delayed limb paralysis. Also provided are methods for stimulating a primary T cell response comprising stimulating cytotoxic T cells against a first tumor antigen and a secondary T cell response comprising stimulating effector T cells and/or memory T cells against a first tumor antigen and/or against a second tumor antigen using the bi-specific antibodies described herein.
FILED	Friday, November 07, 2014
APPL NO	15/034782
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/32 (20130101) Original (OR) Class C07K 16/2809 (20130101) C07K 2317/31 (20130101) C07K 2317/34 (20130101) C07K 2317/73 (20130101) C07K 2317/622 (20130101)
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10240130 — CDNA clone-launched platform for high-yield production of inactivated zika virus

US 10240130	Xie et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Xuping Xie (Galveston, Texas); Chao Shan (Galveston, Texas); Pei-Yong Shi (Galveston, Texas)
ABSTRACT	The invention generally relates to the development of variant Zika strains, cDNA clones and mRNA transcripts that contain specific mutations in the Zika ORF, and methods for producing high yields of Zika viruses (“ZIKVs”) using these variant cDNA clones, transcripts and strains. The produced ZIKVs can be used for the manufacture of purified inactivated vaccines (PIVs), which may be useful for treating ZIKV-related diseases and for providing immunoprotection against ZIKV.
FILED	Thursday, February 15, 2018
APPL NO	15/897488
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/552 (20130101) A61K 2039/575 (20130101) A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2770/24121 (20130101) C12N 2770/24122 (20130101) C12N 2770/24134 (20130101) C12N 2770/24171 (20130101)
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10240146 — Probe library construction

US 10240146	Zhuang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	President and Fellows Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Xiaowei Zhuang (Lexington, Massachusetts); Jeffrey R. Moffitt (Somerville, Massachusetts); Alistair Boettiger (Cambridge, Massachusetts)
ABSTRACT	The present invention generally relates to systems and methods for producing nucleic acids. In some aspects, relatively large quantities of oligonucleotides can be produced, and in some cases, the oligonucleotides may have a variety of different sequences and/or lengths. For instance, a relatively small quantity of oligonucleotides may be amplified to produce a large amount of nucleotides. In one set of embodiments, oligonucleotides may be amplified using PCR, then transcribed to produce RNA. The RNA may then be reverse transcribed to produce DNA, and optionally, the RNA may be selectively degraded or removed, relative to the DNA. In one set of embodiments, the oligonucleotides may be chemically modified. These modifications may include, but are not limited, to the adding of fluorescent dyes or other signaling entities.
FILED	Wednesday, July 29, 2015
APPL NO	15/329651
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 15/1093 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6837 (20130101) C12Q 1/6841 (20130101) C12Q 1/6869 (20130101) C12Q 2521/107 (20130101) C12Q 2525/143 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/179 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) C12Q 2565/102 (20130101) C12Q 2565/514 (20130101) Electric Digital Data Processing G06F 19/20 (20130101) G06F 19/22 (20130101) G06F 19/24 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101)
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10240156 — Modulation of synaptic maintenance

US 10240156	Barres et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Ben A. Barres (Palo Alto, California); Alexander H. Stephan (Stanford, California); Beth A. Stevens (Milton, Massachusetts)
ABSTRACT	C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including treating and preventing neurodegenerative diseases such as Alzheimer's disease.
FILED	Thursday, July 28, 2016
APPL NO	15/222603
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/727 (20130101) A61K 31/727 (20130101) A61K 31/7088 (20130101) A61K 38/177 (20130101) A61K 38/482 (20130101) A61K 38/1774 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2320/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/5058 (20130101) G01N 33/6872 (20130101) G01N 33/6896 (20130101) G01N 2333/4716 (20130101) G01N 2500/04 (20130101) G01N 2800/28 (20130101) G01N 2800/2821 (20130101)
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10240157 — Diagnostic and screening methods for atopic dermatitis

US 10240157	Wilson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Sarah R. Wilson (Berkeley, California); Lydia Thé (Berkeley, California); Diana M. Bautista (Berkeley, California)
ABSTRACT	The present disclosure provides methods for identifying agents that are candidate agents for treating atopic dermatitis. The present disclosure provides methods for diagnosing atopic dermatitis. The present disclosure provides compositions and methods for treating atopic dermatitis.
FILED	Thursday, September 14, 2017
APPL NO	15/704917
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5035 (20130101) G01N 33/6863 (20130101) G01N 33/6872 (20130101) G01N 2500/02 (20130101) G01N 2500/10 (20130101) G01N 2800/202 (20130101)
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10240158 — Compositions and methods for making selenocysteine containing polypeptides

US 10240158	Soll et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF)
APPLICANT(S)	Yale University (New Haven, Connecticut)
ASSIGNEE(S)	Yale University (New Haven, Connecticut)
INVENTOR(S)	Dieter Soll (Guilford, Connecticut); Caroline Aldag (New Haven, Connecticut); Michael Hohn (Scotch Plains, New Jersey); Corwin Miller (New Haven, Connecticut)
ABSTRACT	Non-naturally occurring tRNA^Secand methods of using them for recombinant expression of proteins engineered to include one or more selenocysteine residues are disclosed. The non-naturally occurring tRNA^Seccan be used for recombinant manufacture of selenocysteine containing polypeptides encoded by mRNA without the requirement of an SECIS element. In some embodiments, selenocysteine containing polypeptides are manufactured by co-expressing a non-naturally occurring tRNA^Seca recombinant expression system, such as E. coli, with SerRS, EF-Tu, SelA, or PSTK and SepSecS, and an mRNA with at least one codon that recognizes the anticodon of the non-naturally occurring tRNA^Sec.
FILED	Tuesday, July 05, 2016
APPL NO	15/202194
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/67 (20130101) C12N 15/70 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101)
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10240175 — Compositions and methods for producing benzylisoquinoline alkaloids

US 10240175	Smolke et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Christina D. Smolke (Menlo Park, California); Kristy M. Hawkins (Oakland, California)
ABSTRACT	The present invention relates to host cells that produce compounds that are characterized as benzylisoquinolines, as well as select precursors and intermediates thereof. The host cells comprise one, two or more heterologous coding sequences wherein each of the heterologous coding sequences encodes an enzyme involved in the metabolic pathway of a benzylisoquinoline, or its precursors or intermediates from a starting compound. The invention also relates to methods of producing the benzylisoquinoline, as well as select precursors and intermediates thereof by culturing the host cells under culture conditions that promote expression of the enzymes that produce the benzylisoquinoline or precursors or intermediates thereof.
FILED	Wednesday, March 23, 2016
APPL NO	15/078874
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0022 (20130101) C12N 9/0059 (20130101) C12N 9/88 (20130101) C12N 9/1007 (20130101) C12N 9/1096 (20130101) C12N 15/81 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/24 (20130101) C12P 13/001 (20130101) C12P 17/12 (20130101) Original (OR) Class C12P 17/182 (20130101)
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10240176 — Compositions and methods for producing benzylisoquinoline alkaloids

US 10240176	Smolke et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Christina D. Smolke (Menlo Park, California); Kristy M. Hawkins (Oakland, California)
ABSTRACT	The present invention relates to host cells that produce compounds that are characterized as benzylisoquinolines, as well as select precursors and intermediates thereof. The host cells comprise one, two or more heterologous coding sequences wherein each of the heterologous coding sequences encodes an enzyme involved in the metabolic pathway of a benzylisoquinoline, or its precursors or intermediates from a starting compound. The invention also relates to methods of producing the benzylisoquinoline, as well as select precursors and intermediates thereof by culturing the host cells under culture conditions that promote expression of the enzymes that produce the benzylisoquinoline or precursors or intermediates thereof.
FILED	Tuesday, April 26, 2016
APPL NO	15/139263
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0022 (20130101) C12N 9/0059 (20130101) C12N 9/88 (20130101) C12N 9/1007 (20130101) C12N 9/1096 (20130101) C12N 15/81 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/24 (20130101) C12P 13/001 (20130101) C12P 17/12 (20130101) Original (OR) Class C12P 17/182 (20130101)
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10240186 — Devices, systems, and methods for magnetic separation

US 10240186	Ionescu-Zanetti et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Cristian Ionescu-Zanetti (Berkeley, California); Joshua Tanner Nevill (El Cerrito, California); Michael Schwartz (Oakland, California); Carolyn G. Conant (San Francisco, California); Roger Rudoff (Cupertino, California)
ASSIGNEE(S)	FLUXION BIOSCIENCES, INC. (South San Francisco, California)
INVENTOR(S)	Cristian Ionescu-Zanetti (Berkeley, California); Joshua Tanner Nevill (El Cerrito, California); Michael Schwartz (Oakland, California); Carolyn G. Conant (San Francisco, California); Roger Rudoff (Cupertino, California)
ABSTRACT	Methods, microfluidic devices, and instruments for magnetic separation of particles from a fluid are described. Examples include microfluidic devices having a removable portion. Examples include microfluidic devices having one or more regions of reduced fluid velocity. Examples further including instruments having pneumatic interfaces. Examples further includes instruments having controllable magnets, imaging components, or combinations thereof.
FILED	Thursday, July 14, 2011
APPL NO	13/183271
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 7/52 (20130101) B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0883 (20130101) B01L 2400/043 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/288 (20130101) B03C 2201/18 (20130101) B03C 2201/26 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 2563/143 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54326 (20130101)
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10240188 — Detection of chemical modifications in nucleic acids

US 10240188	Weeks et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Kevin M. Weeks (Carrboro, North Carolina); Nathan Siegfried (Chapel Hill, North Carolina); Philip Homan (Chapel Hill, North Carolina); Steven Busan (Chapel Hill, North Carolina); Oleg V. Favorov (Chapel Hill, North Carolina)
ABSTRACT	The presently disclosed subject matter relates to technology and methods for analyzing the structure of nucleic acid molecules, such as RNA molecules. More particularly, the presently disclosed subject matter is directed to methods of compositions for, and computer program products for nucleic acid analysis, such as RNA structure analysis.
FILED	Tuesday, October 07, 2014
APPL NO	15/027813
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1241 (20130101) C12N 15/01 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) Original (OR) Class
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10240195 — Chemical methods for producing tagged nucleotides

US 10240195	Fuller et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	Carl W. Fuller (Berkeley Heights, New Jersey); Shiv Kumar (Belle Mead, New Jersey); Jingyue Ju (Englewood Cliffs, New Jersey); Randall Davis (Pleasanton, California); Roger Chen (Saratoga, California)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); GENIA TECHNOLOGIES, INC. (Mountain View, California)
INVENTOR(S)	Carl W. Fuller (Berkeley Heights, New Jersey); Shiv Kumar (Belle Mead, New Jersey); Jingyue Ju (Englewood Cliffs, New Jersey); Randall Davis (Pleasanton, California); Roger Chen (Saratoga, California)
ABSTRACT	This disclosure provides systems and methods for attaching nanopore-detectable tags to nucleotides. The disclosure also provides methods for sequencing nucleic acids using the disclosed tagged nucleotides.
FILED	Monday, March 23, 2015
APPL NO	14/666124
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 17/02 (20130101) C07H 19/10 (20130101) C07H 19/20 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6874 (20130101) Original (OR) Class
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10240206 — Biomarkers and methods for predicting benefit of adjuvant chemotherapy

US 10240206	Cress et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida)
ASSIGNEE(S)	H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida)
INVENTOR(S)	W. Douglas Cress (Lutz, Florida); Dung-Tsa Chen (Tampa, Florida)
ABSTRACT	Biomarkers, methods, assays, and kits are provided for predicting the efficacy of adjuvant chemotherapy (ACT) in a subject with early-stage non-small cell lung cancer (NSCLC).
FILED	Monday, February 03, 2014
APPL NO	14/765156
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Electric Digital Data Processing G06F 19/22 (20130101)
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10240208 — MicroRNA assay for detection and management of pancreatic cancer precursors

US 10240208	Malafa et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida)
ASSIGNEE(S)	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida)
INVENTOR(S)	Mokenge P. Malafa (Tampa, Florida); Jennifer Permuth (Tampa, Florida); Dung-Tsa Chen (Tampa, Florida)
ABSTRACT	The current invention pertains to miRNAs that are differentially expressed in samples of an individual having pancreatic cancer, or having a high risk of developing pancreatic cancer, as compared to the corresponding sample of an individual not having pancreatic cancer, or having low risk of developing pancreatic cancer, respectively. In certain embodiments, the miRNAs are differentially expressed in a tissue sample or blood plasma sample of an individual having a pancreatic lesion and having a high risk of developing pancreatic cancer as compared to the corresponding tissue sample or blood sample of an individual having the pancreatic lesion and having no risk or low risk of developing pancreatic cancer. These differentially expressed miRNAs can be used as biomarkers for diagnosis, treatment, and/or prevention of pancreatic cancer, particularly, in a subject having a pancreatic lesion. Microarray containing miRNAs indicative of the presence of pancreatic cancer, or having a high risk of pancreatic cancer development, particularly, in a subject having a pancreatic lesion, and methods of use of the microarrays are also provided.
FILED	Tuesday, March 31, 2015
APPL NO	15/300808
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101)
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10241015 — Cryogenic cooling positioning apparatus, methods and applications

US 10241015	Hollabaugh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Mitegen, LLC (Ithaca, New York)
ASSIGNEE(S)	Mitegen, LLC (Ithaca, New York)
INVENTOR(S)	Stephen Hollabaugh (Ithaca, New York); Robert Newman (Groton, New York); David Closs (Freeville, New York)
ABSTRACT	A method and a cryogenic sample positioning system are provided which include: a sample holder cassette that is vertically coupled to a carousel gear through a first shaft. Each sample holder cassette has a first degree of rotation about the first shaft. A first planet drive gear underlies and is vertically coupled to the carousel gear through a second shaft that extends from the carousel gear through the first planet drive gear. The carousel gear has a second degree of rotation about the second shaft that is different from the first degree of rotation. A planet gear that is laterally connected to a second planet drive gear is interposed between each of the carousel gear and the first planet drive gear. Each of the planet gear and the second planet drive gear selectively define the first degree of rotation, without affecting the second degree of rotation of the carousel gear.
FILED	Monday, July 24, 2017
APPL NO	15/657988
ART UNIT	3655 — Material and Article Handling
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0242 (20130101) A01N 1/0257 (20130101) A01N 1/0268 (20130101) Gearing F16H 1/28 (20130101) F16H 57/08 (20130101) F16H 57/12 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 19/005 (20130101) Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 3/11 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/42 (20130101) Original (OR) Class G01N 23/20033 (20130101) G01N 35/025 (20130101) G01N 2035/0486 (20130101) G01N 2223/604 (20130101)
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10241041 — Biological tissue analysis by inverse spectroscopic optical coherence tomography

US 10241041	Backman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Vadim Backman (Chicago, Illinois); Ji Yi (Evanston, Illinois)
ABSTRACT	A method and system to measure and image the full optical scattering properties by inverse spectroscopic optical coherence tomography (ISOCT) is disclosed. Tissue is modeled as a medium with continuous refractive index (RI) fluctuation and such a fluctuation is described by the RI correlation functions. By measuring optical quantities of tissue (including the scattering power of the OCT spectrum, the reflection albedo α defined as the ratio or scattering coefficient μ_s, and the back-scattering coefficient μ_b), the RI correlation function can be inversely deduced and the full set of optical scattering properties can be obtained.
FILED	Tuesday, May 09, 2017
APPL NO	15/590745
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0066 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4795 (20130101) Original (OR) Class
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10241110 — Plasmonic biosensors with built-in artificial antibodies

US 10241110	Singamaneni et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Washington University in St. Louis (St. Louis, Missouri)
ASSIGNEE(S)	Washington University in St. Louis (St. Louis, Missouri)
INVENTOR(S)	Srikanth Singamaneni (St. Louis, Missouri); Limei Tian (St. Louis, Missouri); Keng-Ku Liu (Philadelphia, Pennsylvania); Abdennour Abbas (St. Louis, Missouri); Jeremiah J. Morrissey (St. Louis, Missouri); Evan D. Kharasch (St. Louis, Missouri)
ABSTRACT	Plasmonic nanotransducers, methods of preparing plasmonic nanotransducers, and methods for label-free detection of target molecules are disclosed. The plasmonic nanotransducers include hollow nanostructure cores and artificial antibodies. The plasmonic nanotransducers are exposed to a biological sample that can contain the specific target molecules. The plasmonic nanotransducers can be analyzed with surface enhanced Raman scattering techniques and/or localized surface plasmon resonance techniques to quantify the amount of the target molecule in the sample.
FILED	Friday, October 17, 2014
APPL NO	15/030004
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) G01N 33/553 (20130101) G01N 33/54346 (20130101) G01N 33/54373 (20130101) Original (OR) Class
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10241113 — CD28 expression during lenalidomide immune modulation

US 10241113	Burnette et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida)
ASSIGNEE(S)	H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida)
INVENTOR(S)	Pearlie Burnette (Tampa, Florida); Jessica M. McDaniel (Etna, Ohio)
ABSTRACT	Disclosed are compositions and methods for predicting responsiveness of a subject to treatment with lenalidomide (LEN) by assaying a sample from the subject for surface expression of CD28 on T-cells. Also provided is a method of treating a subject for cancer that involves assaying a sample from the subject for surface expression of CD28 on T-cells and then treating them with LEN if they do not have reduced CD28 surface expression on the T-cells. Also provided is a method for promoting responsiveness of a subject to LEN by administering to the subject a composition that promotes expression of CD28 on the surface of T-cells.
FILED	Thursday, October 10, 2013
APPL NO	14/434542
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/454 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) Original (OR) Class G01N 33/56972 (20130101) G01N 2333/70521 (20130101) G01N 2800/52 (20130101)
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10241173 — Systems and methods for designing magnetic resonance fingerprinting imaging parameters

US 10241173	Zhao et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts); The University of Southern California (Los Angeles, California)
INVENTOR(S)	Bo Zhao (Malden, Massachusetts); Justin P. Haldar (Los Angeles, California); Lawrence Wald (Cambridge, Massachusetts)
ABSTRACT	Systems and methods for acquiring magnetic resonance fingerprinting (MRF) imaging data from a subject using a magnetic resonance imaging (MRI) system are provided. The method includes receiving an indication of an MRF imaging process to be performed by the MRI system and receiving a desired design objective for the MRF imaging process and a configuration metric associated with the MRF imaging process. The method further includes using the configuration metric to bound a variance of tissue parameter estimates associated with the MRF imaging process and determine imaging parameters that achieve the desired design objective. The method also includes performing the MRF imaging process using the determined imaging parameters to acquire MRF data using the MRI system.
FILED	Monday, March 06, 2017
APPL NO	15/450127
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) Original (OR) Class G01R 33/5608 (20130101)
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10241176 — Systems and methods for statistical reconstruction of magnetic resonance fingerprinting data

US 10241176	Zhao et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Bo Zhao (Malden, Massachusetts); Kawin Setsompop (Cambridge, Massachusetts); Lawrence Wald (Cambridge, Massachusetts)
ABSTRACT	Systems and methods for reconstructing magnetic resonance (MR) tissue parameter maps of a subject from magnetic resonance fingerprinting (MRF) data acquired using a magnetic resonance imaging (MRI) system. The method includes providing MRF data acquired from a subject using an MRI system and performing an iterative, maximum-likelihood reconstruction of the MRF data to create MR tissue parameter maps of the subject.
FILED	Wednesday, January 18, 2017
APPL NO	15/409378
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/5608 (20130101) Original (OR) Class
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10241178 — System and method for magnetic resonance fingerprinting at high field strengths

US 10241178	Brady-Kalnay et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Susann Brady-Kalnay (Cleveland, Ohio); Vikas Gulani (Cleveland Heights, Ohio); Mark Griswold (Shaker Heights, Ohio); Chris Flask (Avon Lake, Ohio); Lan Lu (Cleveland, Ohio); Ying Gao (Cleveland, Ohio); Yun Jiang (Cleveland, Ohio); Dan Ma (Cleveland, Ohio)
ABSTRACT	A system and method is provided for operating a high-field magnetic resonance (MR) system includes performing a series of data acquisition modules without respiratory gating. Each data acquisition module is formed of a steady-state free precession pulse sequence. Performing the series of data acquisition modules includes varying at least one of an amplitude of an excitation pulse or a repetition time of the steady-state free precession pulse sequence between adjacent data acquisition modules in the series of data acquisition modules to acquire a series of MR data with random or pseudo-random imaging acquisition parameters. The series of MR data is compared to a dictionary of signal evolution profiles to determine a match between the series of MR data with at least one signal evolution profile in the dictionary indicating at least one quantitative parameter in the subject.
FILED	Tuesday, May 31, 2016
APPL NO	15/169166
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/5614 (20130101) Original (OR) Class G01R 33/56509 (20130101) G01R 33/56563 (20130101)
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10241199 — Ultrasonic/photoacoustic imaging devices and methods

US 10241199	Witte et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF)
APPLICANT(S)	The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S)	The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S)	Russell S. Witte (Tucson, Arizona); Leonardo Gabriel Montilla (Tucson, Arizona); Ragnar Olafsson (Tucson, Arizona); Charles M. Ingram (Tucson, Arizona); Zhaohui Wang (Tucson, Arizona); Robert A. Norwood (Tucson, Arizona); Charles Greenlee (Tucson, Arizona)
ABSTRACT	Devices are disclosed for obtaining data of a sample, particularly data capable of being processed to produce an image of a region of the sample. An exemplary device includes a light-beam source, an acoustic-wave source, an optical element, and an acoustic detector. The optical element is transmissive to a light beam produced by the light-beam source and reflective to acoustic waves produced by the acoustic-wave source. The optical element is situated to direct the transmitted light beam and reflected acoustic wave simultaneously along an optical axis to be incident at a situs in or on a sample to cause the sample to produce acoustic echoes from the incident acoustic waves while also producing photoacoustic waves from the incident light beam photoacoustically interacting with the situs. The acoustic detector is placed to receive and detect the acoustic echoes and the photoacoustic waves from the situs. The acoustic detector can comprise one or more hydrophones exploiting the acousto-electric effect.
FILED	Tuesday, November 04, 2014
APPL NO	14/533013
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0093 (20130101) A61B 5/0095 (20130101) A61B 5/7257 (20130101) A61B 8/08 (20130101) A61B 8/0825 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) G01N 29/0672 (20130101) G01N 29/2418 (20130101) G01N 2291/02475 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52 (20130101) G01S 7/52017 (20130101) Original (OR) Class G01S 15/02 (20130101)
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10241233 — Methods and apparatus for monitoring interactions between particles and molecules using nanophotonic trapping

US 10241233	Erickson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S)	CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S)	David Erickson (Ithaca, New York); Pilgyu Kang (Ithaca, New York)
ABSTRACT	A method for characterizing an interaction between a first particle and a second particle is provided. The method includes the steps of: (i) providing an optical trap system including a photonics-based trap, a light source, and a camera; (ii) optically trapping, using the photonics-based trap, the first particle; (iii) obtaining a first measurement of a trap stiffness of the photonics-based trap; (iv) introducing the second particle to the optically trapped particle; (v) incubating the first and second particles under conditions suitable for an interaction between the first and second particles; (vi) obtaining a second measurement of the trap stiffness of the photonics-based trap after the incubation; and (vii) determining, using the first measurement of trap stiffness and the second measurement of trap stiffness, a property of the interaction between the first particle and the second particle.
FILED	Wednesday, August 12, 2015
APPL NO	14/824423
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/25 (20130101) G01N 21/47 (20130101) G01N 33/542 (20130101) Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) Original (OR) Class G02B 21/32 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101)
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10242153 — Method for determining the risk profile of neoplastic tissue

US 10242153	Aneja et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	NOVAZOI THERANOSTICS (Rolling Hills Estates, California)
ASSIGNEE(S)	NOVAZOI THERANOSTICS (Rancho Palos Verdes, California)
INVENTOR(S)	Ritu Aneja (Lilburn, Georgia); Padmashree C. G. Rida (Plano, Texas)
ABSTRACT	A method of computing the risk profile of a neoplastic tissue in a patient is disclosed. The method includes the steps of (a) processing a sample of tumor tissue or cancer cells from the patient in a form suitable for visualization and demarcation of cell nuclei, individually distinguishable centrosomes (iCTRs) and megacentrosomes (mCTRs) in a region of interest (ROI) defined by a plurality of cell nuclei; (b) determining the numbers of iCTRs and mCTRs associated with each cell nucleus in the ROI; (c) determining the volume of each iCTR and mCTR in the ROI; and (d) calculating one or more centrosome amplification scores (CASs) values for the sample based on steps (b) and (c), wherein the one or more CASs indicate the severity of centrosome amplification, the frequency of centrosome amplification, or both, and wherein the one or more scores provide a measure of a level of risk and/or a prognosis associated with the neoplastic tissue.
FILED	Monday, January 30, 2017
APPL NO	15/419693
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/343 (20130101) A61K 31/365 (20130101) A61K 31/473 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/57407 (20130101) G01N 33/57415 (20130101) G01N 33/57438 (20130101) G01N 33/57496 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) G06F 19/18 (20130101) G06F 19/20 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101)
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10242155 — BAMBAM: parallel comparative analysis of high-throughput sequencing data

US 10242155	Sanborn et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	John Z. Sanborn (Santa Cruz, California); David Haussler (Santa Cruz, California)
ABSTRACT	A differential sequence object is constructed on the basis of alignment of sub-strings via incremental synchronization of sequence strings using known positions of the sub-strings relative to a reference genome sequence. An output file is then generated that comprises only relevant changes with respect to the reference genome.
FILED	Thursday, December 11, 2014
APPL NO	14/567774
ART UNIT	3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC	Electric Digital Data Processing G06F 3/04845 (20130101) G06F 17/241 (20130101) G06F 19/00 (20130101) G06F 19/18 (20130101) G06F 19/22 (20130101) G06F 19/28 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/24 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) Technologies for Adaptation to Climate Change Y02A 90/22 (20180101) Y02A 90/26 (20180101)
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10243325 — Method for stabilizing atomic devices

US 10243325	Shah
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	QuSpin, Inc. (Louisville, Colorado)
ASSIGNEE(S)	Quspin, Inc. (Louisville, Colorado)
INVENTOR(S)	Vishal Shah (Westminster, Colorado)
ABSTRACT	A two-stage laser stabilization method is described to simultaneously servo two coupled laser parameters that control the wavelength of a laser, such as the laser injection current and the laser temperature, in order to simultaneously stabilize the laser frequency and output power. Two error signals are generated by passing the laser light through a frequency discriminator, such as an atomic resonance, to generate two control loops for the two coupled laser parameters. A primary control loop servos the faster laser parameter, such as the laser injection current, by direct use of the error signal. A secondary slower control loop ensures that this said error signal will remain at zero, by controlling the second laser parameter, such as the laser temperature.
FILED	Thursday, February 02, 2017
APPL NO	15/422946
ART UNIT	2881 — Optics
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0612 (20130101) H01S 5/0683 (20130101) Original (OR) Class
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Department of Defense (DOD)

10238370 — Steerable shape sensing biopsy needle

US 10238370	Park et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Medical Research Acquisition Activity (USAMRAA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) Small Business Administration (SBA) Small Business Innovation Research (SBIR) Small Business Technology Transfer (STTR)
APPLICANT(S)	Intelligent Fiber Optic Systems, Inc (Santa Clara, California)
ASSIGNEE(S)	INTELLIGENT FIBER OPTIC SYSTEMS, INC. (Santa Clara, California)
INVENTOR(S)	Yong-Lae Park (Stanford, California); Richard James Black (Menlo Park, California); Behzad Moslehi (Los Altos, California); Mark R. Cutkosky (Palo Alto, California); Santhi Elayaperumal (Stanford, California); Bruce Daniel (Stanford, California); Alan Yeung (Stanford, California); Vahid Sotoudeh (Los Altos, California)
ABSTRACT	A biopsy needle has a central axis and includes one or more sensing regions, each sensing region formed by a plurality of sensing optical fibers located over a particular extent of said central axis and inside the outer shell of the needle. The sensing optical fibers are coupled to a wavelength interrogator. A steerable catheter has a central axis and outer shell, the outer shell coupled to a plurality of optical fibers in sensing regions and actuation regions, the sensing regions formed over particular extents of the central axis by bonding gratings to the inner surface of the outer shell, and the actuation regions formed by coupling optical energy into shape memory alloys bonded to the outer shell.
FILED	Friday, January 03, 2014
APPL NO	14/147486
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 10/0266 (20130101) Original (OR) Class A61B 2017/003 (20130101) A61B 2017/00106 (20130101) A61B 2034/2061 (20160201) A61B 2090/065 (20160201)
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10238496 — Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same

US 10238496	Biris
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S)	BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
INVENTOR(S)	Alexandru S. Biris (Little Rock, Arkansas)
ABSTRACT	A biocompatible structure includes one or more base structures for regeneration of different tissues. Each base structure includes alternately stacked polymer layers and spacer layers. The polymer layer includes a polymer and tissue forming nanoparticles. The polymer includes polyurethane. The tissue forming nanoparticles includes hydroxypatites (HAP) nanoparticles, polymeric nanoparticles, or nanofibers. The spacer layer includes bone particles, polymeric nanoparticles, or nanofibers. The weight percentage of tissue forming nanoparticles to the polymer in the polymer layer in one base structure is different from that in the other base structures. A method of producing the biocompatible structure includes forming multiple base structures stacked together, coating the stacked multiple base structures, and plasma treating the coated structure.
FILED	Thursday, June 15, 2017
APPL NO	15/624425
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/08 (20130101) A61F 2/28 (20130101) Original (OR) Class A61F 2002/0894 (20130101) A61F 2002/2825 (20130101) A61F 2002/2835 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/38 (20130101) A61L 27/44 (20130101) A61L 27/46 (20130101) A61L 27/46 (20130101) A61L 27/46 (20130101) A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 27/365 (20130101) A61L 27/3608 (20130101) A61L 2300/64 (20130101) A61L 2300/252 (20130101) A61L 2300/254 (20130101) A61L 2300/412 (20130101) A61L 2300/414 (20130101) A61L 2400/12 (20130101) A61L 2430/02 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/24 (20130101) B32B 37/26 (20130101) B32B 38/0004 (20130101) B32B 2037/243 (20130101) B32B 2307/7163 (20130101) B32B 2317/00 (20130101) B32B 2323/04 (20130101) B32B 2333/04 (20130101) B32B 2375/00 (20130101) B32B 2386/00 (20130101) Compositions of Macromolecular Compounds C08L 5/00 (20130101) C08L 67/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/1062 (20150115) Y10T 156/1074 (20150115)
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10238532 — Body temperature controlling system

US 10238532	Cesaroni
FUNDED BY	Department of Defense (DOD) United States Special Operations Command (SOCOM)
APPLICANT(S)	Anthony J. Cesaroni (Sarasota, Florida)
ASSIGNEE(S)	Cesaroni Technology Incorporated (Sarasota, Florida)
INVENTOR(S)	Anthony J. Cesaroni (Sarasota, Florida)
ABSTRACT	The present invention is directed to a body temperature controlling system comprising at least one member receiving a flow of gas from at least one blower in communication with said at least one member, said at least one member directing said flow of gas onto a wearer thereof.
FILED	Wednesday, June 11, 2008
APPL NO	12/137414
ART UNIT	3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/02 (20130101) Original (OR) Class A61F 2007/0063 (20130101) A61F 2007/0069 (20130101) A61F 2007/0075 (20130101) A61F 2007/0234 (20130101)
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10238618 — Compositions and methods for diagnosis and treatment of anemia

US 10238618	Venn-Watson et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Stephanie Kay Venn-Watson (San Diego, California); Mark Baird (San Diego, California)
ABSTRACT	Compositions including a fatty acid, such as an odd chain fatty acid or a very long even chain fatty acid, and salts and derivatives thereof, and methods for treatment and prophylaxis of conditions related to anemic conditions, are provided, including compositions and methods for treating anemic conditions such as hemolytic anemia and anemia of chronic disease, and other related conditions.
FILED	Thursday, December 29, 2016
APPL NO	15/393771
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/20 (20130101) Original (OR) Class A61K 31/20 (20130101) A61K 31/202 (20130101) A61K 31/202 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101)
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10238639 — Azophenols as ERG oncogene inhibitors

US 10238639	Dobi et al.
FUNDED BY	Department of Defense (DOD) Uniformed Services University of the Health Sciences (USUHS) Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
APPLICANT(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
ASSIGNEE(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
INVENTOR(S)	Albert L. Dobi (Rockville, Maryland); Clifton L. Dalgard (Chevy Chase, Maryland); Shiv K. Srivastava (Potomac, Maryland)
ABSTRACT	Selective azophenol inhibitors of a wild type or an altered ERG protein expression are described, where the inhibitors represent a compound of Formula (I) or Formula (II) wherein X, X₁, X₂, X₃, X₄and X₅, R₁through R₄and R₉are as described.
FILED	Friday, September 09, 2016
APPL NO	15/561626
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/426 (20130101) Original (OR) Class A61K 31/4402 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 245/00 (20130101) C07C 245/02 (20130101) C07C 245/04 (20130101) Heterocyclic Compounds C07D 277/50 (20130101)
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10238689 — Methods for combating bacterial infections by killing persister cells with mitomycin C and/or cisplatin

US 10238689	Wood et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Thomas Wood (Port Matilda, Pennsylvania); Brian Kwan (State College, Pennsylvania); Nityananda Chowdhury (State College, Pennsylvania)
ABSTRACT	The present disclosure provides a method for killing persister cells with mitomycin C and/or cisplatin, or derivatives thereof. Recalcitrant infections are difficult to treat due to persister cells, a subpopulation of all bacterial populations that is highly tolerant against all traditional antibiotics since the cells are dormant and antibiotics are designed to kill growing cells. Here, we show that MMC and cisplatin eradicate persister cells through a growth-independent mechanism, cross-linking DNA. We find both agents are effective against both planktonic cultures and highly robust biofilm cultures for a broad range of bacterial species, including commensal Escherichia coli K-12 as well as pathogenic species of E. coli, Staphylococcus aureus, and Pseudomonas aeruginosa. In certain approaches cisplatin is superior to MMC.
FILED	Wednesday, October 04, 2017
APPL NO	15/724998
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/33 (20130101) A61K 31/40 (20130101) A61K 31/282 (20130101) A61K 31/282 (20130101) A61K 31/407 (20130101) A61K 31/407 (20130101) A61K 33/24 (20130101) Original (OR) Class A61K 33/24 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101)
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10238769 — Graft for directed vascular and lymphatic regeneration and methods to guide endothelial cell assembly

US 10238769	Paukshto et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Fibralign Corporation (Union City, California); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	Fibralign Corporation (Union City, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Michael V. Paukshto (Foster City, California); John P. Cooke (Palo Alto, California); Tatiana S. Zaitseva (San Jose, California); Ngan F. Huang (Mountain View, California); Gerald G. Fuller (Stanford, California); George R. Martin (Rockville, Maryland)
ABSTRACT	Embodiments of the present invention relate to a therapeutic device (graft) comprising a collagen membrane having an aligned uniaxial or biaxial structure such that mammalian cells plated on the membrane align mainly along the direction of the collagen fibrils. In a further aspect, a graft comprising a substantially tubular body, wherein the body has an exterior surface, an interior surface, and at least one lumen extending therethrough such that a fluid flow through the lumen can direct mammalian cell migration. In a further aspect, mammalian cells or growth and angiogenic factors can be optionally attached to the exterior and/or interior surface of the substantially tubular body. In various aspects, the graft can be used as a vascular prosthesis, a stent, or a nerve regeneration scaffold. Methods of preparing and implanting same are also provided.
FILED	Thursday, October 11, 2012
APPL NO	14/351128
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) Original (OR) Class A61L 27/507 (20130101) A61L 27/3604 (20130101) A61L 27/3808 (20130101) A61L 2430/32 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/26 (20150115) Y10T 428/24711 (20150115) Y10T 428/249921 (20150401)
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10238904 — Mutant organophosphorus acid anhydrolases and uses thereof

US 10238904	Guelta et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Aberdeen Proving Ground (APG) Combat Capabilities Development Command (CCDC) Chemical Biological Center (CCDC CBC) Research, Development and Engineering Command (RDECOM) Edgewood Chemical Biological Center (ECBC)
APPLICANT(S)	U.S. Army Edgewood Chemical Biological Center (APG, Maryland)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Mark A Guelta (White Marsh, Maryland); Melissa M. Dixon (Abingdon, Maryland); Steven P Harvey (Lutherville, Maryland)
ABSTRACT	Disclosed herein are non-wild-type organophosphorus acid anhydrolases having two site mutations, methods of production, and methods of use to effectively degrade toxic chemicals such as ((RS)-Propan-2-yl methylphosphonofluoridate) (Sarin) and other organophosphorus compounds.
FILED	Wednesday, September 13, 2017
APPL NO	15/703123
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/02 (20130101) Original (OR) Class A62D 2101/02 (20130101) A62D 2101/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Enzymes C12Y 301/03 (20130101)
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10239012 — Methods of separating molecules

US 10239012	First et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Defense Science and Engineering Graduate Fellowship (NDSEG) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET) Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
ASSIGNEE(S)	The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S)	Eric L. First (Princeton, New Jersey); M. M. Faruque Hasan (Princeton, New Jersey); Christodoulos A. Floudas (Princeton, New Jersey)
ABSTRACT	Disclosed herein are new methods, machines, processes, and systems for separating molecules by determining better materials and process optimization conditions. As a result of these advances, this disclosure provides improved carbon dioxide capture, better flue gas treatments, and more efficient methods of purifying gases have been developed. Optimal sorbents can be obtained by using a computational screening method that selects microporous structures (e.g. zeolites and metal-organic frameworks) from a database of materials with the greatest potential for cost-effective separations. The disclosed methods are the first to consider both the size and shape of the adsorbent material. This is also the first disclosure to consider the process application and cost when selecting which material to use.
FILED	Wednesday, February 05, 2014
APPL NO	14/766388
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/04 (20130101) Original (OR) Class B01D 53/26 (20130101) B01D 53/047 (20130101) B01D 2253/108 (20130101) B01D 2253/116 (20130101) B01D 2253/204 (20130101) B01D 2256/245 (20130101) B01D 2257/80 (20130101) B01D 2257/102 (20130101) B01D 2257/504 (20130101) B01D 2257/7025 (20130101) Electric Digital Data Processing G06F 17/50 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/08 (20130101) Y02C 20/20 (20130101)
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10239021 — Fouling resistant coating for filtration membranes and methods of producing and using same

US 10239021	Ganguli et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Rahul Ganguli (Oak Park, California); Vivek Mehrotra (Simi Valley, California); Tony Ten-Luen Liao (South Pasadena, California)
ASSIGNEE(S)	Teledyne Scientific and Imaging, LLC (Thousand Oaks, California)
INVENTOR(S)	Rahul Ganguli (Oak Park, California); Vivek Mehrotra (Simi Valley, California); Tony Ten-Luen Liao (South Pasadena, California)
ABSTRACT	A conformal coating that resists fouling by waterborne contamination in aquatic environments, a method for fabricating the coating, and a filter having such a coating are disclosed. The coating comprises a hydrophilic polymer and a surfactant wherein the surfactant undergoes a phase change upon exposure to a saline solution. Also disclosed are in situ methods for regenerating anti-fouling filters having the fouling resistant coating.
FILED	Thursday, June 14, 2012
APPL NO	13/523037
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 65/08 (20130101) B01D 67/0088 (20130101) Original (OR) Class B01D 71/68 (20130101) B01D 2325/04 (20130101) B01D 2325/48 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/005 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1687 (20130101) C09D 7/63 (20180101) C09D 101/28 (20130101) C09D 101/284 (20130101) C09D 101/286 (20130101) C09D 105/00 (20130101) C09D 105/12 (20130101)
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10239254 — Method of fabricating shape memory films

US 10239254	Tan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S)	Loon-Seng Tan (Centerville, Ohio); David Huabin Wang (Beavercreek, Ohio)
ABSTRACT	A method for fabricating a shape memory polymer into a three-dimensional object is provided. The method includes forming a film of crosslinked poly(amic acid) on a substrate to provide a laminated substrate; forming the laminated substrate into a first configuration that is in a three-dimensional form; curing the cross-linked poly(amic acid) to provide the shape memory polymer having a permanent shape corresponding to the first configuration; and removing the substrate from the laminated substrate to provide the three-dimensional object comprising the shape memory polymer. The formation of the laminated substrate into the three-dimensional object may be based on origami techniques.
FILED	Thursday, January 28, 2016
APPL NO	15/009356
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/003 (20130101) B29C 41/46 (20130101) B29C 61/003 (20130101) Original (OR) Class B29C 69/00 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2079/08 (20130101) B29K 2995/0037 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/1071 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/00 (20130101) C08J 2379/08 (20130101)
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10239631 — Aircraft receptacle

US 10239631	Lewis et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Life Cycle Management Center (AFLCMC)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Brian Lewis (Seattle, Washington); Bruce M. Whiteman (Mukilteo, Washington); Christopher Mark Alley (Seattle, Washington)
ABSTRACT	A system and method for an aircraft receptacle. The aircraft receptacle comprises an actuator connected to a number of latches and a tension spring connected to the number of latches. The actuator is part of an actuation system. The elastic member holds the number of latches in a disengaged position after failure of the actuation system.
FILED	Monday, July 13, 2015
APPL NO	14/797796
ART UNIT	3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 39/06 (20130101) Original (OR) Class
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10239637 — System and method for arresting and neutralizing unmanned vehicles

US 10239637	Ashdown et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Jonathan Ashdown (Greenwich, New York); Paul Sikora (Holland Patent, New York); Brendon Poland (Holland Patent, New York)
ABSTRACT	The use of shielded material in a deployable vehicle arresting and containment device that, when used for the interception of an unmanned vehicle, effectively achieves RF isolation of that vehicle, breaking all external communications with that vehicle. This apparatus, which may have internal and external antennas, could enable a variety of advanced effects such as localized GPS and command and control link spoofing and jamming as well as providing a vehicle for signal intercept and intelligence solutions. Additionally, due to the shielding properties of the arresting and containment device, semi-destructive means such as localized EMPs could be used to damage the encapsulated unmanned vehicle electronics.
FILED	Thursday, August 25, 2016
APPL NO	15/246850
ART UNIT	3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Ships or Other Waterborne Vessels; Equipment for Shipping B63B 35/00 (20130101) B63B 2035/006 (20130101) Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/182 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/02 (20130101) Original (OR) Class Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 7/005 (20130101) F41H 13/0006 (20130101)
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10239757 — Nanostructured silicon nitride synthesis from agriculture waste

US 10239757	Qadri et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Syed B. Qadri (Fairfax Station, Virginia); Bhakta B. Rath (Oakton, Virginia); Edward P. Gorzkowski, III (Odenton, Maryland)
ABSTRACT	A method of making Si₃N₄nanotubes and nanorods comprising adding agricultural husk material powder to a container, wherein the container is a covered boron nitride crucible, creating an inert atmosphere of nitrogen inside the container, applying heat, heating the agricultural husk material, and reacting the agricultural husk material and forming silicon nitride, wherein the silicon nitride is nanotubes and nanorods.
FILED	Friday, May 26, 2017
APPL NO	15/606425
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 21/0685 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/13 (20130101) C01P 2004/16 (20130101)
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10239893 — Controlling the isomerization rate of Azo-BF2 switches using aggregation

US 10239893	Abrahamian et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S)	THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S)	Ivan Abrahamian (Hanover, New Hampshire); Russell P. Hughes (Lebanon, New Hampshire); Yin Nelson (Hanover, New Hampshire); Hai Qian (Hanover, New Hampshire)
ABSTRACT	Provided herein are photochromic organic compounds of Formula I or Formula II, which are useful as molecular switches capable of being triggered via a cis/trans isomerization process. Methods of using the molecular switch compounds to form photopharmaceutical compounds that may be used to provide selective spatiotemporal activation of pharmaceutical agents are also disclosed.
FILED	Tuesday, October 11, 2016
APPL NO	15/290881
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/066 (20130101) A61N 2005/0662 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/02 (20130101) C07F 5/022 (20130101) Original (OR) Class
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10239916 — Controlled modulation of amino acid side chain length of peptide antigens

US 10239916	Ioannides et al.
FUNDED BY	Department of Defense (DOD) Uniformed Services University of the Health Sciences (USUHS) Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas); Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Rockville, Maryland)
ASSIGNEE(S)	Board of Regents, The University of Texas Systems (Austin, Texas); Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Rockville, Maryland)
INVENTOR(S)	Constantin G. Ioannides (Houston, Texas); Martin L. Campbell (Colorado Springs, Colorado); Catherine A. O'Brian (Chicago, Illinois); George E. Peoples (San Antonio, Texas)
ABSTRACT	The invention provides a method for the creation of peptide antigens comprising epitopes with at least a first modification comprising a shortened or lengthened amino acid side chain. By extension or shortening of the side chain with CH3/CH2 groups, for example, made by computer assisted modeling of the tumor antigen (peptide) bound in the MHC-I-groove, immunogenicity can be improved with minimal modification of adjacent tertiary structure, thereby avoiding cross-reactivity. Provided by the invention are methods of creating such antigens, as well as methods for therapeutic or prophylactic treatment of various conditions comprising administration of the antigens.
FILED	Tuesday, July 29, 2014
APPL NO	14/445776
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 7/06 (20130101) Original (OR) Class C07K 14/4705 (20130101)
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10240010 — Graphitic nanocomposites in solid state matrices and methods for making same

US 10240010	Curran et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Seamus Curran (Pearland, Texas); Kang-Shyang Liao (Houston, Texas); Alexander Wang (Houston, Texas)
ASSIGNEE(S)	UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S)	Seamus Curran (Pearland, Texas); Kang-Shyang Liao (Houston, Texas); Alexander Wang (Houston, Texas)
ABSTRACT	A composition and method for fabricating graphitic nanocomposites in solid state matrices is presented. The process for fabricating graphitic nanocomposites in solid state matrices may include selecting one or a mixture of specific graphitic nanomaterials. The graphitic nanomaterial(s) may be functionalizing with a moiety similar to the building blocks of the solid state matrices. The functionalized graphitic nanomaterials are mixed with the building blocks of the solid state matrices. The mixture may be cured, which causes in situ formation of the sol-gel solid state matrices that entraps and/or covalently links with the graphitic nanomaterials during the network growing process. This process allows the nanomaterials to be introduced into the matrices homogeneously without forming large aggregations.
FILED	Wednesday, September 13, 2017
APPL NO	15/703408
ART UNIT	1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/20 (20170801) C01B 32/21 (20170801) C01B 32/152 (20170801) C01B 32/156 (20170801) C01B 32/168 (20170801) C01B 32/194 (20170801) C01B 32/354 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/13 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/005 (20130101) Original (OR) Class C08J 2379/04 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/56 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/74 (20130101) D06M 13/507 (20130101) D06M 13/513 (20130101) D06M 2400/02 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101)
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10240227 — Zirconium based bulk metallic glasses with hafnium

US 10240227	Peker et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Washington State University (Pullman, Washington)
ASSIGNEE(S)	Washington State University (Pullman, Washington)
INVENTOR(S)	Atakan Peker (Spokane, Washington); Dongchun Qiao (Spokane, Washington)
ABSTRACT	Various embodiments of zirconium based bulk metallic glass with hafnium are described herein. In one embodiment, an alloy composition includes zirconium (Zr), hafnium (Hf), copper (Cu), aluminum (Al), at least one element from a group consisting of niobium (Nb) and titanium (Ti), and at least one element from a group consisting of nickel (Ni), iron (Fe), and cobalt (Co).
FILED	Friday, April 29, 2016
APPL NO	15/142728
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Alloys C22C 1/002 (20130101) C22C 1/03 (20130101) C22C 16/00 (20130101) C22C 30/00 (20130101) C22C 30/02 (20130101) C22C 45/10 (20130101) Original (OR) Class C22C 2200/02 (20130101)
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10240243 — Flow distributor hole pattern

US 10240243	O'Coin
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S)	Hamilton Sundstrand Corporation (Charlotte, North Carolina)
INVENTOR(S)	James R. O'Coin (Somers, Connecticut)
ABSTRACT	A flow distributor may comprise an inner surface, an outer surface, and a plurality of holes circumferentially disposed in the flow distributor and extending from the inner surface to the outer surface. Each of the holes may comprise an inlet defined at the inner surface and an outlet defined at the outer surface, wherein each inlet is axially offset from a circumferentially adjacent inlet.
FILED	Friday, May 05, 2017
APPL NO	15/588060
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/006 (20130101) C02F 1/4602 (20130101) C02F 1/4674 (20130101) C02F 1/46104 (20130101) C02F 2201/4618 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/26 (20130101) Original (OR) Class C25B 9/06 (20130101) C25B 15/08 (20130101)
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10240244 — Portable, liquid free, electroless, electrochemical deposition of metal on conductive and nonconductive surfaces

US 10240244	Arumugam et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Oceanit Laboratories, Inc. (Honolulu, Hawaii)
ASSIGNEE(S)	Oceanit Laboratories, Inc. (Honolulu, Hawaii)
INVENTOR(S)	Ganesh Kumar Arumugam (Honolulu, Hawaii); Ashavani Kumar (Honolulu, Hawaii); Vinod P. Veedu (Houston, Texas); Sumil Thapa (Honolulu, Hawaii)
ABSTRACT	Electroless plating is accomplished by forming a metal salt and a polymer solution as a binder into a solid electrolyte block and depositing metal on the surface by rubbing or brushing the solid electrolyte block onto a surface with minimal or no water and without an electric potential/power source. The solid electrolyte block is also conformable/moldable and can be used to deposit metal on to both conductive and nonconductive surface through electroless deposition process.
FILED	Thursday, March 12, 2015
APPL NO	14/656217
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/003 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0005 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7722 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 5/22 (20130101) Original (OR) Class C25D 17/005 (20130101) C25D 17/14 (20130101)
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10240338 — Transportable modular system for covered isolation of assets

US 10240338	Durst et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America as Represented by The Secretary of The Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Bartley P. Durst (Clinton, Mississippi); Pamela Kinnebrew (Vicksburg, Mississippi); Nicholas Boone (Vicksburg, Mississippi); William Heard (Madison, Mississippi); Thomas Slawson (Vicksburg, Mississippi); Michael J. Roth (Raymond, Mississippi); Omar Flores (Vicksburg, Mississippi); Omar E. Esquilin-Mangual (Vicksburg, Mississippi)
ABSTRACT	An easily assembled, transportable, re-deployable, modular, protective, double-roof system is disclosed which is compatible with other Modular Protective System (MPS) components and can be assembled in a variety of configurations to provide soldiers and equipment with protective enclosures.
FILED	Monday, December 03, 2012
APPL NO	13/693016
ART UNIT	3638 — Static Structures, Supports and Furniture
CURRENT CPC	General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/18 (20130101) E04B 1/1903 (20130101) E04B 1/34331 (20130101) Original (OR) Class Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 9/04 (20130101) E04H 9/14 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/04 (20130101) F41H 5/013 (20130101) F41H 5/24 (20130101) Blasting F42D 5/045 (20130101) Technologies for Adaptation to Climate Change Y02A 50/14 (20180101)
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10240470 — Baffle for gas turbine engine vane

US 10240470	Hagan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Benjamin F. Hagan (Manchester, Connecticut); Ryan A. Waite (South Windsor, Connecticut); Brandon W. Spangler (Vernon, Connecticut); Steven B. Gautschi (Naugatuck, Connecticut)
ABSTRACT	A vane structure includes an airfoil section with a first inner airfoil wall surface and a second inner airfoil wall surface. A baffle is mounted within the airfoil section between the first inner airfoil wall surface and the second inner airfoil wall surface.
FILED	Monday, June 30, 2014
APPL NO	14/911148
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/189 (20130101) F01D 9/065 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/126 (20130101) F05D 2250/182 (20130101) F05D 2250/183 (20130101) F05D 2250/184 (20130101) F05D 2260/204 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/673 (20130101) Y02T 50/676 (20130101)
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10240479 — Variable area turbine arrangement for a gas turbine engine

US 10240479	Surace
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Raymond Surace (Newington, Connecticut)
ABSTRACT	A variable area turbine arrangement according to an exemplary aspect of the present disclosure includes, among other things, a first turbine section having at least a first variable vane row and a second turbine section downstream from the first turbine section and having at least a second variable vane row. A transition duct is disposed between the first turbine section and the second turbine section.
FILED	Monday, August 04, 2014
APPL NO	14/909209
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/06 (20130101) F01D 9/041 (20130101) F01D 17/162 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/20 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101)
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10240537 — Metering valve assembly and method of assembly thereof

US 10240537	Cadman et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	John Michael Cadman (Mason, Ohio); David Richard Barnhart (Jefferson, Ohio)
ABSTRACT	A valve assembly includes a body including an inlet port, an outlet port, and a flow passage extending therebetween. The flow passage includes a plurality of valve seats in a stepped arrangement between the inlet port and the outlet port. The valve assembly further includes a valve stem positioned within the flow passage. The valve stem includes at least one shaft and a poppet disk positioned at one end of the at least one shaft, and at least one reed petal coupled to the at least one shaft. The poppet disk is engageable with a first valve seat of the plurality of valve seats, and the at least one reed petal is engageable with a second valve seat of the plurality of valve seats.
FILED	Tuesday, August 09, 2016
APPL NO	15/232426
ART UNIT	3753 — Fluid Handling and Dispensing
CURRENT CPC	Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/232 (20130101) F02C 9/263 (20130101) Original (OR) Class Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 1/443 (20130101) F16K 15/028 (20130101) F16K 15/148 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/7891 (20150401) Y10T 137/87394 (20150401)
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10240815 — Efficient dissociation of water vapor in arrays of microchannel plasma devices

US 10240815	Dai et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Zhen Dai (Urbana, Illinois); Thomas J. Houlahan (Urbana, Illinois); J. Gary Eden (Champaign, Illinois); Sung-Jin Park (Champaign, Illinois)
ABSTRACT	The invention provides methods and systems for water dissociation with microplasma generated in microchannel plasma arrays or chips. Preferred methods and systems introduce water vapor into a microchannel plasma array. Electrical power is applied to the microchannel plasma array to create a plasma chemical reaction of the water vapor in the microchannel plasma array. Dissociated hydrogen and/or oxygen gas is collected at an output of the microchannel plasma array. The water vapor can be entrained in a carrier gas, but is preferably introduced without carrier gas. Direct introduction of water vapor has been demonstrated to provide efficiencies at an above 60%. The use of carrier gas reduces efficiency, but still exceeds efficiencies of prior methods discussed in the background.
FILED	Monday, May 09, 2016
APPL NO	15/150107
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 19/0093 (20130101) B01J 2219/0084 (20130101) B01J 2219/0086 (20130101) B01J 2219/00786 (20130101) B01J 2219/00795 (20130101) B01J 2219/00824 (20130101) B01J 2219/0841 (20130101) B01J 2219/00853 (20130101) B01J 2219/0894 (20130101) B01J 2219/00959 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/045 (20130101) C01B 13/0207 (20130101) C01B 2203/0861 (20130101) Fluid Heaters, e.g Water or Air Heaters, Having Heat Generating Means, in General F24H 1/186 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/364 (20130101)
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10240823 — Air conditioning system

US 10240823	Barot et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	OxiCool, Inc. (Malvern, Pennsylvania)
ASSIGNEE(S)	OxiCool Inc (Malvern, Pennsylvania); The United States of America As Represented By The Secretary of the Navy (Arlington, Virginia)
INVENTOR(S)	Ravikant T. Barot (Phoenixville, Pennsylvania); Jonathan William Kaufman (Leonardtown, Maryland); Stephen M. Coleman (Lusby, Maryland)
ABSTRACT	An air conditioning system that includes desiccant compartments for holding a desiccant; a heat exchanger, a blower and a vessel. The heat exchanger can be filled with a heat transfer medium, while the blower blows ambient air by the heat exchanger such that the blown air is cooled and the heat exchanger is warmed such that thermal energy increases and is transferred from the air to the heat transfer medium causing the heat transfer medium to turn into vapor. The vapor is then diffused to one of the desiccant compartments such that the vapor is adsorbed onto the desiccant creating a mixture. Then an energy source is applied to the mixture such that the vapor and desiccant are separated. The separated vapor is transported to the vessel where it is condensed and then sent back to the heat exchanger, such that the system is able to be continuously operating.
FILED	Thursday, September 17, 2015
APPL NO	14/856661
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 15/00 (20130101) F25B 17/083 (20130101) Original (OR) Class F25B 27/00 (20130101) Technologies for Adaptation to Climate Change Y02A 30/278 (20180101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/64 (20130101)
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10240882 — Crush inducing cartridge chamber

US 10240882	Hoffman
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Brian R. Hoffman (Bangor, Pennsylvania)
ABSTRACT	A bottleneck cartridge chamber wherein a circumferential relief recess is placed within the shoulder region of the chamber. As opposed to the continuous angled shoulder of conventional cartridge chambers, the proposed relief recess is envisioned as an angular segment of larger included angle than the conventional chamber shoulder angle (thereby creating a compound angle cartridge chamber shoulder region) or a radial recess that would eliminate a portion of the conventional chamber shoulder.
FILED	Tuesday, September 11, 2018
APPL NO	16/127441
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/12 (20130101) Original (OR) Class
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10240884 — Mountable fixture for absorbing recoil

US 10240884	De Leon et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Jorge David De Leon (Ben Alton, Maryland); James F. Cahill (Fredericksburg, Virginia); Ishankumar Patel (Glen Allen, Virginia); Reginald Heggie (Fredericksburg, Virginia); Gregorio Morales-Caez (Fredericksburg, Virginia); Nelson C. Hall (Fredericksburg, Virginia); Arnold R. Hamlet, III (Montross, Virginia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jorge David De Leon (Ben Alton, Maryland); James F. Cahill (Fredericksburg, Virginia); Ishankumar Patel (Glen Allen, Virginia); Reginald Heggie (Fredericksburg, Virginia); Gregorio Morales-Caez (Fredericksburg, Virginia); Nelson C. Hall (Fredericksburg, Virginia); Arnold R. Hamlet, III (Montross, Virginia)
ABSTRACT	A fixture is provided for supporting load from weapons recoil, being mountable on a flat bed of a road vehicle disposed on ground. The flat bed can receive a weapons mount. The vehicle has longitudinal, lateral and vertical orientation directions. The fixture includes a horizontal deck, a slide assembly, a dampener housing, port and starboard lateral beams, together with first, second and third posts. The horizontal deck receives the weapons mount. The slide assembly supports the deck. The dampener housing receives the slide assembly. The port and starboard lateral beams extend laterally from the dampener housing. The first and second posts extend vertically downward from their corresponding beams to engage the ground. The third post extends vertically downward from the housing to engage the ground. Brackets on the slide assembly extend longitudinally from the platform for enabling the vehicle to drive away from the fixture. The posts are retractable for stowage and extendible for raising the flat bed above the ground.
FILED	Wednesday, January 31, 2018
APPL NO	15/884875
ART UNIT	3634 — Static Structures, Supports and Furniture
CURRENT CPC	Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 23/26 (20130101) F41A 23/34 (20130101) Original (OR) Class F41A 23/52 (20130101) F41A 23/56 (20130101) F41A 25/12 (20130101)
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10240896 — Tube to bulkhead bonded joint design

US 10240896	Mijares et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S)	Orlando L. Mijares (Tucson, Arizona); Keith A. Elkins (Tucson, Arizona); Jack W. Reany (Corona De Tuc, Arizona)
ABSTRACT	A tube to bulkhead joint is provided. The joint includes a bulkhead defining an aperture and comprising an interior facing sidewall at the aperture, a tubular element, which is insertible into the aperture, the tubular element including an end sized to fit into the aperture and slotted to form multiple deflectable fingers, and adhesive disposable between at least the multiple deflectable fingers and the interior facing sidewall of the aperture.
FILED	Thursday, March 12, 2015
APPL NO	14/656128
ART UNIT	3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 11/006 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 37/008 (20130101) Apparatus for Launching Projectiles or Missiles From Barrels, e.g Cannons; Launchers for Rockets or Torpedoes; Harpoon Guns F41F 3/06 (20130101) F41F 3/042 (20130101) Original (OR) Class F41F 3/065 (20130101) F41F 3/073 (20130101)
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10240970 — Motion compensating infrasound sensor

US 10240970	Grimmett et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Douglas John Grimmett (San Diego, California); Randall Plate (San Diego, California); Chad Williams (New Albany, Mississippi); Carrick Talmadge (Oxford, Mississippi)
ASSIGNEE(S)	The United States, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Douglas John Grimmett (San Diego, California); Randall Plate (San Diego, California); Chad Williams (New Albany, Mississippi); Carrick Talmadge (Oxford, Mississippi)
ABSTRACT	Systems and methods for maritime infrasound detection can include at least one waterborne platform. A microbarometer, inertial measurement unit (IMU) and heave cancellation component (HCC) can be mounted on the waterborne platform. The HCC can receive a pressure input from the microbarometer and the IMU to generate an output pressure that can be indicative of an infrasound signal of interest (SOI). The HCC can further include a filter and an adaptive algorithm. The filter can receive IMU pressure and environment noise pressure as inputs. An error signal from the HCC output can also be supplied through a closed feedback loop that includes a Recursive Least Squares adaptive algorithm, which can further include a weighted, tapped delay line. The system can further include a remote data center for receiving the HCC output from the waterborne platform(s), which can be buoys, vessel or USV's.
FILED	Monday, September 18, 2017
APPL NO	15/707269
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 3/00 (20130101) Original (OR) Class G01H 9/004 (20130101)
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10241017 — High temperature heating system

US 10241017	Keranen et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Bruker Nano, Inc. (Santa Barbara, California)
ASSIGNEE(S)	Bruker Nano, Inc. (Santa Barbara, California)
INVENTOR(S)	Lucas Paul Keranen (Hutchinson, Minnesota); Syed Amanulla Syed Asif (Bloomington, Minnesota); Ryan Major (Crystal, Minnesota); Yunje Oh (Medina, Minnesota)
ABSTRACT	A sample gripping and heating assembly includes an assembly housing and first and second heating grips coupled with the assembly housing. The first and second heating grips each include a gripping surface, and the gripping surfaces of the first and second heating grips are opposed to each other. Each of the first and second heating grips further includes a heating element adjacent to the gripping surface. Optionally, the sample gripping and heating assembly is included in a heating system including a probe heater having a probe heating element for heating of a probe. The heating system is included with a testing assembly having a stage coupled with the sample gripping and heating assembly, and a transducer assembly coupled with the probe heater.
FILED	Wednesday, November 28, 2012
APPL NO	14/361094
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/08 (20130101) G01N 3/18 (20130101) G01N 3/54 (20130101) Original (OR) Class G01N 2203/0078 (20130101) G01N 2203/0226 (20130101) G01N 2203/0282 (20130101) G01N 2203/0286 (20130101) G01N 2203/0482 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 1/023 (20130101) H05B 3/32 (20130101)
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10241018 — Wear test apparatus

US 10241018	Zafred et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Department of Energy (DOE) Knolls Atomic Power Laboratory (KAPL) National Nuclear Security Administration (NNSA) Naval Nuclear Laboratory (NNL)
APPLICANT(S)	United States Department of Energy (Washington, District of Columbia)
ASSIGNEE(S)	U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S)	Paolo R. Zafred (Murrysville, Pennsylvania); William H. Howland (Wexford, Pennsylvania)
ABSTRACT	Disclosed is an exemplary test apparatus having an autoclave head, a fretting mechanism connected on a first end to a first side of the autoclave head, a load train operably connected with a first end of the fretting mechanism, an autoclave adapter connected on a first side to a second side of the autoclave head, and a force balance assembly connected to a second side of the autoclave head and configured to equalize a pressure acting on the load train. Certain exemplary embodiments include an upper plate, a plurality of upper tie rods connected to a first side of the upper plate and a second side of the autoclave adapter, a lower plate, a plurality of lower tie rods connected to the first side of the autoclave head and a first side of the lower plate, and a pressure vessel sealingly connected to the first side of the autoclave head.
FILED	Thursday, October 27, 2016
APPL NO	15/335542
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/32 (20130101) G01N 3/56 (20130101) Original (OR) Class G01N 2203/0005 (20130101) G01N 2203/0008 (20130101) G01N 2203/023 (20130101) G01N 2203/0222 (20130101) G01N 2203/0224 (20130101) G01N 2203/0232 (20130101)
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10241028 — Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures

US 10241028	Rowe et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) National Science Foundation (NSF)
APPLICANT(S)	Steven M. Rowe (Birmingham, Alabama); Guillermo J. Tearney (Cambridge, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts); Linbo Liu (Cambridge, Massachusetts); Eric J. Sorscher (Birmingham, Alabama); Kengyeh Ken Chu (Jamaica Plain, Massachusetts); Bradford James Diephuis (Brookline, Massachusetts); Eric James Wilsterman (Boston, Massachusetts); Gregory Andrew Dierksen (Brookline, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Steven M. Rowe (Birmingham, Alabama); Guillermo J. Tearney (Cambridge, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts); Linbo Liu (Cambridge, Massachusetts); Eric J. Sorscher (Birmingham, Alabama); Kengyeh Ken Chu (Jamaica Plain, Massachusetts); Bradford James Diephuis (Brookline, Massachusetts); Eric James Wilsterman (Boston, Massachusetts); Gregory Andrew Dierksen (Brookline, Massachusetts)
ABSTRACT	Exemplary apparatus and method can be provided for obtaining data regarding a plurality of samples. For example, using at least one arrangement, it is possible to receive interferometric information that is based on radiations provided from a reference and the samples that are provided in respective chambers. Alternatively and/or in addition, based on the interferometric information, it is possible to discriminate between agents to identify a particular agent that affects a particular function within at least one of the samples.
FILED	Monday, August 27, 2012
APPL NO	14/240938
ART UNIT	2886 — Optics
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0205 (20130101) G01B 9/02044 (20130101) G01B 9/02091 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/45 (20130101) G01J 9/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/14 (20130101) G01N 15/0205 (20130101) G01N 21/17 (20130101) Original (OR) Class G01N 21/35 (20130101) G01N 21/45 (20130101) G01N 21/4788 (20130101) G01N 21/4795 (20130101) G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 29/00 (20130101) G01N 2021/653 (20130101) G01N 2021/655 (20130101)
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10241110 — Plasmonic biosensors with built-in artificial antibodies

US 10241110	Singamaneni et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Washington University in St. Louis (St. Louis, Missouri)
ASSIGNEE(S)	Washington University in St. Louis (St. Louis, Missouri)
INVENTOR(S)	Srikanth Singamaneni (St. Louis, Missouri); Limei Tian (St. Louis, Missouri); Keng-Ku Liu (Philadelphia, Pennsylvania); Abdennour Abbas (St. Louis, Missouri); Jeremiah J. Morrissey (St. Louis, Missouri); Evan D. Kharasch (St. Louis, Missouri)
ABSTRACT	Plasmonic nanotransducers, methods of preparing plasmonic nanotransducers, and methods for label-free detection of target molecules are disclosed. The plasmonic nanotransducers include hollow nanostructure cores and artificial antibodies. The plasmonic nanotransducers are exposed to a biological sample that can contain the specific target molecules. The plasmonic nanotransducers can be analyzed with surface enhanced Raman scattering techniques and/or localized surface plasmon resonance techniques to quantify the amount of the target molecule in the sample.
FILED	Friday, October 17, 2014
APPL NO	15/030004
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) G01N 33/553 (20130101) G01N 33/54346 (20130101) G01N 33/54373 (20130101) Original (OR) Class
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10241191 — Multi-sensor target tracking using multiple hypothesis testing

US 10241191	Paluszek et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	PRINCETON SATELLITE SYSTEMS, INC. (Plainsboro, New Jersey)
ASSIGNEE(S)	PRINCETON SATELLITE SYSTEMS, INC. (Plainsboro, New Jersey)
INVENTOR(S)	Michael A. Paluszek (Princeton, New Jersey); Joseph Mueller (Champlin, Minnesota); Stephanie Thomas (West Windsor, New Jersey)
ABSTRACT	Disclosed a multi-sensor multiple hypotheses testing tracking system. The multi-hypothesis testing system associates measurements from multiple sensors with tracks. Measurements are incorporated using a Kalman Filter and the same filters are used to propagate the trajectories of the tracks.
FILED	Tuesday, August 25, 2015
APPL NO	14/835094
ART UNIT	2827 — Semiconductors/Memory
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/16 (20130101) G01S 5/18 (20130101) G01S 5/0294 (20130101) Original (OR) Class G01S 11/12 (20130101) G01S 13/726 (20130101) G01S 13/931 (20130101) G01S 15/66 (20130101) G01S 15/931 (20130101)
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10241293 — Methods and apparatus for deployable sparse-aperture telescopes

US 10241293	Reid et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Bryan M. Reid (Chelmsford, Massachusetts); Mark Silver (Bedford, Massachusetts); Robert Martinez (Providence, Rhode Island); Alan Decew (West Newton, Massachusetts); Adam Shabshelowitz (Cambridge, Massachusetts); Michael Chrisp (Burlington, Massachusetts)
ABSTRACT	An imaging system includes a metering structure and a plurality of foldable members disposed around a periphery of the metering structure. Each foldable member in the plurality of foldable members includes an arm comprising a strain deployable composite and a reflector disposed on the arm. The arm in a respective foldable member in the plurality of foldable members is configured to hold the respective foldable member toward the metering structure in a first state and to hold the respective foldable member away from the metering structure in a second state such that the reflector of the respective foldable member forms part of a sparse aperture in the second state.
FILED	Friday, September 25, 2015
APPL NO	14/865646
ART UNIT	2872 — Optics
CURRENT CPC	Cosmonautics; Vehicles or Equipment Therefor B64G 1/66 (20130101) Optical Elements, Systems, or Apparatus G02B 7/183 (20130101) Original (OR) Class G02B 7/1827 (20130101) G02B 17/0808 (20130101) G02B 23/16 (20130101)
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10241850 — Non-magnetodielectric flux concentrator

US 10241850	Holcomb
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Grid Logic Incorporated (Lapeer, Michigan)
ASSIGNEE(S)	Grid Logic Incorporated (Lapeer, Michigan)
INVENTOR(S)	Matthew J. Holcomb (Metamora, Michigan)
ABSTRACT	The invention also provides a heating apparatus including a holder capable of holding at least one part, an electric current generator and a flux concentrator electrically connected to the electric current generator, the flux concentrator being made of a non-magneto-dielectric material and having a coil with at least one turn forming an inductor to generate an alternating magnetic field that is driven by the alternating electric field, the alternating magnetic field resonating at a frequency of at least 1 MHz in response to the alternating electric current.
FILED	Wednesday, August 13, 2014
APPL NO	14/459096
ART UNIT	3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) Electric Digital Data Processing G06F 11/073 (20130101) Original (OR) Class Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/40 (20130101) H05B 6/101 (20130101)
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10241963 — Hash-based synchronization of geospatial vector features

US 10241963	Ioup et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Elias Ioup (New Orleans, Louisiana); Norman Schoenhardt (New Orleans, Louisiana); John T. Sample (Pearl River, Louisiana)
ABSTRACT	Embodiments relate to hash-based synchronization of geospatial vector features. Initially, a list of spatial data layers in a source spatial datastore is obtained. For each of the spatial data layers, a source layer hash is determined for a source data layer of the spatial data layers, a destination data layer is identified in a destination spatial datastore that is related to the source data layer, where the destination data layer is associated with a destination layer hash, and in response to determining that the source layer hash and the destination layer hash do not match, source features from the source data layer are selectively synchronized to the destination data layer.
FILED	Friday, May 19, 2017
APPL NO	15/600561
ART UNIT	2161 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 16/29 (20190101) Original (OR) Class G06F 16/137 (20190101) G06F 16/152 (20190101) G06F 16/275 (20190101)
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10242043 — Software security via control flow integrity checking

US 10242043	Pike et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Galois, Inc. (Portland, Oregon)
ASSIGNEE(S)	Galois, Inc. (Portland, Oregon)
INVENTOR(S)	Lee Pike (Portland, Oregon); Patrick Christopher Hickey (Portland, Oregon); Aaron Tomb (Portland, Oregon); Eric Mertens (Portland, Oregon)
ABSTRACT	Various technologies related to control flow integrity checking are described herein and can be used to greatly improve software security. During static analysis, a canonical control flow graph can be built. Execution of a program can be interrupted at runtime, and the call stack can be observed to verify control flow integrity of the program using the canonical control flow graph. Attacks using stack tampering can be avoided, regardless of how the stack tampering is achieved. Non-invasive techniques can be used, making the technologies applicable in situations where source code is not available. Real-time operating system protection can be supported.
FILED	Thursday, December 14, 2017
APPL NO	15/842577
ART UNIT	2431 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 11/3604 (20130101) G06F 17/30371 (20130101) Original (OR) Class G06F 21/52 (20130101) G06F 21/566 (20130101)
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10242190 — System and method for detection of malicious code by iterative emulation of microcode

US 10242190	Davidov et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	LEVIATHAN SECURITY GROUP, INC. (Seattle, Washington)
ASSIGNEE(S)	LEVIATHAN SECURITY GROUP, INC. (Seattle, Washington)
INVENTOR(S)	Mikhail Davidov (Seattle, Washington); Patrick Stach (The Woodlands, Texas)
ABSTRACT	Examples of systems, methods and media are shown for iteratively emulating potentially malicious code involving, for each offset of a microarchitecture for the code, emulating a first ring of an operating system, executing a segment of code in the emulated first ring, checking the behavior of the executing code for suspect behavior, and identifying the executing code as malicious code if suspect behavior is detected. Some examples include emulating a second ring of the operating system having a higher level of privilege than the first ring, such that the second ring emulation returns results to the executing code segment, but does not actually perform the functionality in a host platform.
FILED	Thursday, July 23, 2015
APPL NO	14/807330
ART UNIT	2434 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/566 (20130101) Original (OR) Class
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10242194 — Method and apparatus for trusted execution of applications

US 10242194	Sniezek et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Strategic Systems Programs (SSP)
APPLICANT(S)	The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts)
INVENTOR(S)	Bogdan J. Sniezek (Dunstable, Massachusetts); Jennifer E. Manuse (Derry, New Hampshire)
ABSTRACT	A system and methodology for providing trusted execution of applications is provided. The computing system includes system hardware including memory. A Trusted Application Execution Provisioning (TAEP) operating on said computing system enforces a Trusted Application Pattern Space (TAPS) within the memory throughout the execution lifecycle of each application hosted on the computing system. The Trusted Application Execution Provisioning (TAEP) assigns each application a private application instruction space and a private application data in accordance with specifications governing the Trusted Application Pattern Space (TAPS), such that the Trusted Application Execution Provisioning (TAEP) prevents the private application instruction space of each application from being read, inferred, and/or modified by any application, and prevents the private application data space of each application from being read, inferred, and/or modified by other than its assigned application. Upon an extension request by a first application to extend with one or more collaborating applications, the Trusted Application Execution Provisioning (TAEP) assigns an application collaboration data space within the memory in accordance with the specifications governing the Trusted Application Pattern Space (TAPS), such that both the first application and the one or more collaborating applications have access to the application collaboration data space. The Trusted Application Execution Provisioning (TAEP) prevents the application collaboration space from being read, inferred, and/or modified by other than the first application and the one or more collaborating applications.
FILED	Wednesday, May 09, 2018
APPL NO	15/975524
ART UNIT	2196 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/45558 (20130101) G06F 21/53 (20130101) G06F 21/57 (20130101) Original (OR) Class G06F 21/6218 (20130101) G06F 2009/45579 (20130101) G06F 2009/45583 (20130101) G06F 2009/45587 (20130101)
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10242425 — Translation of artificial intelligence representations

US 10242425	Riabov et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Anton V. Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (Port Chester, New York); Octavian Udrea (Ossining, New York)
ABSTRACT	Techniques for translating graphical representations of domain knowledge are provided. In one example, a computer-implemented method comprises receiving, by a device operatively coupled to a processor, a graphical representation of domain knowledge. The graphical representation comprises information indicative of a central concept and at least one chain of events associated with the central concept. The computer-implemented method further comprises translating, by the device, the graphical representation into an artificial intelligence planning problem. The artificial intelligence planning problem is expressed in an artificial intelligence description language. The translating comprises parsing the graphical representation into groupings of terms. A first grouping of terms of the grouping of terms comprises an event from the at least one chain of events and a second grouping of terms of the grouping of terms comprises the information indicative of the central concept. The computer-implemented method also comprises validating, by the device, the artificial intelligence planning problem.
FILED	Thursday, December 14, 2017
APPL NO	15/842252
ART UNIT	2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Electric Digital Data Processing G06F 15/18 (20130101) G06F 17/30277 (20130101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) Image Data Processing or Generation, in General G06T 1/20 (20130101) Original (OR) Class
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10242427 — Deviation magnification: revealing departures from ideal geometries

US 10242427	Wadhwa et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Neal Wadhwa (Cambridge, Massachusetts); Tali Dekel (Cambridge, Massachusetts); Donglai Wei (Arlington, Massachusetts); Frederic Pierre Durand (Somerville, Massachusetts); William T. Freeman (Acton, Massachusetts)
ABSTRACT	Geometries of the structures and objects deviate from their idealized models, while not always visible to the naked eye. Embodiments of the present invention reveal and visualize such subtle geometric deviations, which can contain useful, surprising information. In an embodiment of the present invention, a method can include fitting a model of a geometry to an input image, matting a region of the input image according to the model based on a sampling function, generating a deviation function based on the matted region, extrapolating the deviation function to an image wide warping field, and generating an output image by warping the input image according to the warping. In an embodiment of the present invention, Deviation Magnification inputs takes a still image or frame, fits parametric models to objects of interest, and generates an output image exaggerating departures from ideal geometries.
FILED	Friday, July 29, 2016
APPL NO	15/223438
ART UNIT	2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image Data Processing or Generation, in General G06T 3/0093 (20130101) Original (OR) Class G06T 11/00 (20130101) G06T 11/001 (20130101)
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10242855 — Detector, system and method for droplet and/or cluster beam spectroscopy

US 10242855	Lewis
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as requested by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	William K Lewis (Dayton, Ohio)
ABSTRACT	A beam ionization gauge (BIG) detector is disclosed for use in spectroscopy and configured to receive an analyte beam along a beam path. The BIG detector includes a filament configured to emit electrons and a grid. The grid is positioned substantially adjacent to the filament and configured to produce ions by directing the electrons to collide with the analyte beam along the beam path. A collector is positioned substantially adjacent to the grid to define the beam path therebetween and configured to detect the ions produced by the collisions of electrons with the analyte beam.
FILED	Wednesday, July 19, 2017
APPL NO	15/654147
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/025 (20130101) Original (OR) Class H01J 49/0031 (20130101) H01J 49/147 (20130101) H01J 49/0445 (20130101)
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10242857 — Ion traps with Y-directional ion manipulation for mass spectrometry and related mass spectrometry systems and methods

US 10242857	Ramsey et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	John Michael Ramsey (Chapel Hill, North Carolina); Andrew Hampton (Auburn, Alabama); Kevin Schultze (Chapel Hill, North Carolina)
ABSTRACT	A miniature electrode apparatus is disclosed for trapping charged particles, the apparatus includes, along a longitudinal direction, a first end cap electrode, a central electrode having an aperture, and a second end cap electrode. The aperture is elongated in the lateral plane and extends through the central electrode along the longitudinal direction and the central electrode surrounds the aperture in a lateral plane perpendicular to the longitudinal direction to define a transverse cavity for trapping charged particles. Electric fields can be applied in a y-direction of the lateral plane across one or more planes perpendicular to the longitudinal axis to translocate and/or manipulate ion trajectories.
FILED	Thursday, August 31, 2017
APPL NO	15/692306
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) H01J 49/0027 (20130101) H01J 49/065 (20130101) Original (OR) Class
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10242884 — Integration of air-sensitive two-dimensional materials on arbitrary substrates for the manufacturing of electronic devices

US 10242884	Akinwande et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas); Consiglio Nazionale delle Ricerche (, Italy)
INVENTOR(S)	Deji Akinwande (Austin, Texas); Li Tao (Austin, Texas); Carlo Grazianetti (Borgo Ticino, Italy); Alessandro Molle (Vimercate, Italy)
ABSTRACT	A field-effect transistor and method for fabricating such a field-effect transistor that utilizes an air-sensitive two-dimensional material (e.g., silicene). A film of air-sensitive two-dimensional material is deposited on a crystalized metallic (e.g., Ag) thin film on a substrate (e.g., mica substrate). A capping layer of insulating material (e.g., aluminum oxide) is deposited on the air-sensitive two-dimensional material. The substrate is detached from the metallic thin film/air-sensitive two-dimensional material/insulating material stack structure. The metallic thin film/air-sensitive two-dimensional material/insulating material stack structure is then flipped. The flipped metallic thin film/air-sensitive two-dimensional material/insulating material stack structure is attached to a device substrate followed by having the metallic thin film etched to form contact electrodes. In this manner, the pristine properties of air-sensitive two-dimensional materials are preserved from degradation when exposed to air. Furthermore, this new technique allows safe transfer and device fabrication of air-sensitive two-dimensional materials with a low material and process cost.
FILED	Friday, September 01, 2017
APPL NO	15/693827
ART UNIT	2815 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0242 (20130101) H01L 21/0259 (20130101) H01L 21/02178 (20130101) H01L 21/02381 (20130101) H01L 21/02521 (20130101) H01L 21/02532 (20130101) H01L 21/02535 (20130101) H01L 21/02631 (20130101) H01L 21/6835 (20130101) H01L 21/32133 (20130101) Original (OR) Class H01L 29/66772 (20130101) H01L 29/78603 (20130101) H01L 29/78654 (20130101) H01L 29/78696 (20130101) H01L 2221/68363 (20130101)
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10242968 — Interconnect structure and semiconductor structures for assembly of cryogenic electronic packages

US 10242968	Das et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Rabindra N. Das (Lexington, Massachusetts); Eric A. Dauler (Acton, Massachusetts)
ABSTRACT	A cryogenic electronic package includes at least two superconducting and/or conventional metal semiconductor structures. Each of the semiconductor structures includes a substrate and a superconducting trace. Additionally, each of the semiconductor structures includes a passivation layer and one or more under bump metal (UBM) structures. The cryogenic electronic package also includes one or more superconducting and/or conventional metal interconnect structures disposed between selected ones of the at least two superconducting semiconductor structures. The interconnect structures are electrically coupled to respective ones of the UBM structures of the semiconductor structures to form one or more electrical connections between the semiconductor structures. A method of fabricating a cryogenic electronic package is also provided.
FILED	Wednesday, August 23, 2017
APPL NO	15/684393
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02063 (20130101) H01L 21/02282 (20130101) H01L 21/02345 (20130101) H01L 22/26 (20130101) H01L 23/5226 (20130101) H01L 23/53209 (20130101) H01L 24/05 (20130101) H01L 24/11 (20130101) H01L 24/13 (20130101) H01L 24/81 (20130101) H01L 25/50 (20130101) H01L 25/0652 (20130101) H01L 25/0655 (20130101) H01L 25/0657 (20130101) Original (OR) Class H01L 27/18 (20130101) H01L 2224/117 (20130101) H01L 2224/0401 (20130101) H01L 2224/0558 (20130101) H01L 2224/1111 (20130101) H01L 2224/1147 (20130101) H01L 2224/04042 (20130101) H01L 2224/05111 (20130101) H01L 2224/05111 (20130101) H01L 2224/05116 (20130101) H01L 2224/05116 (20130101) H01L 2224/05169 (20130101) H01L 2224/05169 (20130101) H01L 2224/05609 (20130101) H01L 2224/05609 (20130101) H01L 2224/05644 (20130101) H01L 2224/05644 (20130101) H01L 2224/06181 (20130101) H01L 2224/8181 (20130101) H01L 2224/08503 (20130101) H01L 2224/10126 (20130101) H01L 2224/10145 (20130101) H01L 2224/11001 (20130101) H01L 2224/11005 (20130101) H01L 2224/11462 (20130101) H01L 2224/11472 (20130101) H01L 2224/11474 (20130101) H01L 2224/11902 (20130101) H01L 2224/13023 (20130101) H01L 2224/13082 (20130101) H01L 2224/13109 (20130101) H01L 2224/16013 (20130101) H01L 2224/16145 (20130101) H01L 2224/16145 (20130101) H01L 2224/16146 (20130101) H01L 2224/16148 (20130101) H01L 2224/17181 (20130101) H01L 2224/32145 (20130101) H01L 2224/32145 (20130101) H01L 2224/48091 (20130101) H01L 2224/48091 (20130101) H01L 2224/48137 (20130101) H01L 2224/48227 (20130101) H01L 2224/73204 (20130101) H01L 2224/73204 (20130101) H01L 2224/73207 (20130101) H01L 2224/80896 (20130101) H01L 2224/81815 (20130101) H01L 2224/81815 (20130101) H01L 2224/92125 (20130101) H01L 2225/0651 (20130101) H01L 2225/06513 (20130101) H01L 2225/06517 (20130101) H01L 2225/06531 (20130101) H01L 2225/06541 (20130101) H01L 2225/06568 (20130101) H01L 2225/06572 (20130101) H01L 2924/00 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101)
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10243018 — Non-planar inorganic optoelectronic devices

US 10243018	Forrest et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA)
APPLICANT(S)	Stephen Forrest (Ann Arbor, Michigan); Jeramy D. Zimmerman (Ann Arbor, Michigan); Xin Xu (West Windsor, New Jersey); Christopher Kyle Renshaw (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan); Universal Display Corporation (Ewing, New Jersey)
INVENTOR(S)	Stephen Forrest (Ann Arbor, Michigan); Jeramy D. Zimmerman (Ann Arbor, Michigan); Xin Xu (West Windsor, New Jersey); Christopher Kyle Renshaw (Ann Arbor, Michigan)
ABSTRACT	A device includes a three-dimensionally curved substrate, a patterned metal layer disposed on the curved substrate, and an array of optoelectronic devices, each optoelectronic device including an optoelectronic structure supported by the curved substrate. Each optoelectronic structure includes an inorganic semiconductor stack. The device further includes a set of contact stripes extending across the curved substrate, each optoelectronic structure being coupled to a respective contact stripe of the set of contact stripes. The array of optoelectronic devices is secured to the curved substrate via a bond between the patterned metal layer and the set of contact stripes.
FILED	Friday, May 22, 2015
APPL NO	14/720312
ART UNIT	2894 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1446 (20130101) H01L 27/14618 (20130101) H01L 27/14636 (20130101) H01L 27/14643 (20130101) Original (OR) Class H01L 31/075 (20130101) H01L 31/0304 (20130101) H01L 31/1844 (20130101) H01L 31/1892 (20130101) H01L 31/03926 (20130101) H01L 31/022408 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101) Y02E 10/548 (20130101)
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10243247 — Frequency tunable reflectionless bandstop filter using L-resonators

US 10243247	Chieh et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	SPAWAR Systems Center Pacific (San Diego, California)
ASSIGNEE(S)	The United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jia-Chi S. Chieh (San Diego, California); Jason F. Rowland (San Diego, California)
ABSTRACT	A bandstop filter includes a coupled line bandstop filter, a capacitor and a resistor. The coupled line bandstop filter includes a transmission line element and a shaped transmission line element. The shaped transmission line element includes a coupled line element disposed so as to electromagnetically couple with the transmission line element, and a second line element disposed so as not to be parallel with the transmission line element. The capacitor is electrically connected to the coupled line element. A portion of the received oscillating signal includes a bandstop frequency. Physical attributes of the coupled line bandstop filter, the capacitor and the resistor are such that the portion of the received oscillating signal including the bandstop frequency is attenuated.
FILED	Tuesday, June 13, 2017
APPL NO	15/621219
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/203 (20130101) Original (OR) Class H01P 1/2039 (20130101) H01P 1/20327 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/06 (20130101) H03H 7/18 (20130101) H03H 7/0123 (20130101) H03H 7/0153 (20130101) H03H 9/542 (20130101)
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10243271 — Quasi static antenna design for a non-symmetric electrically small antenna having non-symmetric enclosing surfaces

US 10243271	Jones, III
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	SPAWAR Systems Center Pacific (San Diego, California)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Thomas O. Jones, III (San Diego, California)
ABSTRACT	A quasi-static antenna design is generated for an electrically small non-symmetric dipole antenna having enclosing surfaces that are not symmetrical with the contours of the dipole arms. The shapes of the enclosing surfaces are predefined. The antenna design is selected from among a set of antenna designs, each antenna design having a unique charge distribution geometry and charge distribution properties. The antenna design is selected that produces a desired capacitance, a desired radiation, resistance, and/or a desired Q-factor.
FILED	Tuesday, October 04, 2016
APPL NO	15/284549
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Electric Digital Data Processing G06F 17/5036 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 11/00 (20130101) Antennas, i.e Radio Aerials H01Q 9/28 (20130101) Original (OR) Class H01Q 9/40 (20130101)
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10243301 — Blind mate connector housing and assembly

US 10243301	Bernard et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Robert P. Bernard (McKinney, Texas); James A. Pruett (Allen, Texas)
ABSTRACT	A blind mate connector assembly comprises a first manifold and a second manifold removably coupled to the first manifold that defines a connector housing positionable between a primary electronics assembly and a secondary electronics assembly. A plurality of connector cavities are defined between the first and second manifolds. A plurality of right angle cable connectors, each situated within one of the plurality of connector cavities, extend partially through the connector housing to facilitate blind mate connection between the primary electronics assembly and the secondary electronics assembly. The connector housing comprises at least one mechanical float mechanism configured to facilitate movement of each right angle cable connector in multiple degrees of freedom. The connectors are replaceable by disassembling the first and second manifolds.
FILED	Wednesday, March 15, 2017
APPL NO	15/459295
ART UNIT	2831 — Electrical Circuits and Systems
CURRENT CPC	Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/48 (20130101) H01R 9/05 (20130101) H01R 9/0515 (20130101) H01R 12/91 (20130101) H01R 13/28 (20130101) H01R 13/518 (20130101) H01R 13/567 (20130101) H01R 13/659 (20130101) H01R 13/6315 (20130101) Original (OR) Class H01R 24/38 (20130101) H01R 24/40 (20130101) H01R 24/50 (20130101) H01R 24/545 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 439/902 (20130101)
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10243319 — Tunable laser system and amplifier using a noble gas-filled hollow-core fiber waveguide

US 10243319	Keyser et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Christian K. Keyser (Shalimar, Florida); Chad M. Welsh (Niceville, Florida)
ABSTRACT	An optical system including a laser system for generating a plurality of coaxial laser beams. The laser beams are combined by the laser system for generating at least two different frequency components. One or more hollow core photonic crystal fibers each filled with a noble gas receive the coaxial laser beams from the laser system and generate an idler emission having an idler frequency component according to four-wave mixing of the at least two different frequency components in the one or more hollow core photonic crystal fibers. A control system is configured to control a gas pressure of the one or more hollow core photonic crystal fibers for controlling the idler frequency component of the idler emission.
FILED	Monday, July 09, 2018
APPL NO	16/030085
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/036 (20130101) H01S 3/0092 (20130101) H01S 3/134 (20130101) H01S 3/305 (20130101) H01S 3/1317 (20130101) Original (OR) Class H01S 3/06741 (20130101) H01S 3/094003 (20130101)
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10243328 — Semiconductor laser

US 10243328	Zhang et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Elenion Technologies, LLC (New York, New York)
ASSIGNEE(S)	Elenion Technologies, LLC (New York, New York)
INVENTOR(S)	Yi Zhang (Jersey City, New Jersey); Shuyu Yang (Jersey City, New Jersey); Michael J. Hochberg (New York, New York); Thomas Wetteland Baehr-Jones (Arcadia, California); Saeed Fathololoumi (San Gabriel, California)
ABSTRACT	A hybrid single or multi-wavelength laser using an optical gain element, such as a semiconductor optical amplifier (SOA), for example a QD RSOA, and a semiconductor, e.g. silicon, photonics chip is demonstrated. A plurality, e.g. four, lasing modes at a predetermined, e.g. 2 nm, spacing and less than 3 dB power non-uniformity may be observed, with over 20 mW of total output power. Each lasing peak can be successfully modulated at 10 Gb/s. At 10⁻⁹BER, the receiver power penalty is less than 2.6 dB compared to a conventional commercial laser. An expected application is the provision of a comb laser source for WDM transmission in optical interconnection systems.
FILED	Tuesday, November 14, 2017
APPL NO	15/811937
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/005 (20130101) H01S 3/0078 (20130101) H01S 3/10053 (20130101) H01S 5/14 (20130101) H01S 5/021 (20130101) H01S 5/141 (20130101) Original (OR) Class H01S 5/142 (20130101) H01S 5/146 (20130101) H01S 5/343 (20130101) H01S 5/1032 (20130101) H01S 5/1096 (20130101) H01S 5/3412 (20130101) H01S 5/4062 (20130101) H01S 5/06804 (20130101)
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10243370 — System and method for integrating energy storage into modular power converter

US 10243370	Garces et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
ASSIGNEE(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S)	Luis Jose Garces (Niskayuna, New York); Rui Zhou (Niskayuna, New York); Zhi Zhou (Selkirk, New York); Di Zhang (Niskayuna, New York)
ABSTRACT	A system for integrating energy storage into a modular power converter includes at least one energy storage unit coupled to a first converter for converting a first direct current (DC) voltage of the at least one energy storage unit into a first high frequency alternating current (AC) voltage. At least three phase legs of the modular power converter generate three phase AC voltages. Each phase leg includes a plurality of switching modules connected in series. The switching modules have a plurality of fully controllable semiconductor switches, an energy storage device, and a second converter coupled to the respective energy storage device for converting a second DC voltage of the energy storage device into a second high frequency AC voltage. In the system, three similarly positioned switching modules of the three phase legs form one power unit. Further, a high frequency transformer is provided which has at least one primary winding connected to the first converter and at least three secondary windings, each connected to the second converter of each of the three similarly positioned switching modules. A controller is configured to regulate at least one electrical parameter of the modular power converter.
FILED	Monday, December 07, 2015
APPL NO	14/960729
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/30 (20130101) H02J 3/32 (20130101) H02J 3/387 (20130101) Original (OR) Class Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/15 (20130101) H02M 7/483 (20130101) H02M 2007/4835 (20130101)
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10243696 — Diversity combining of non-coherently modulated LDPC codes in wireless communications

US 10243696	Borle et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	Kapil Borle (Watertown, Massachusetts); Biao Chen (Jamesville, New York); Fangfang Zhu (Bridgewater, New Jersey); Yu Zhao (Somerville, Massachusetts)
ASSIGNEE(S)	Syracuse University (Syracuse, New York)
INVENTOR(S)	Kapil Borle (Watertown, Massachusetts); Biao Chen (Jamesville, New York); Fangfang Zhu (Bridgewater, New Jersey); Yu Zhao (Somerville, Massachusetts)
ABSTRACT	A method of decoding a plurality of diverse signals for low-density parity-check (LDPC) decoders that takes advantage of signal diversity. The method allows for the combining of soft-decision LDPC encoded non-coherently modulated signals, which is in contrast to existing approaches where hard decision combining is used for non-coherently modulated signals. The method includes the steps of inputting each diversity signal into a unique demodulator, and calculating the LLR of each demodulated signal. When the diverse demodulated signals are combined into a single combined signal, each bit of the combined signal is selected according to the value of either the highest LLR value of each bit across the demodulated signals or according to the sum of the LLR of each bit across the demodulated signals.
FILED	Tuesday, November 24, 2015
APPL NO	14/950191
ART UNIT	2631 — Digital Communications
CURRENT CPC	Transmission H04B 7/08 (20130101) H04B 7/0885 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0045 (20130101) H04L 1/0054 (20130101) Original (OR) Class H04L 1/0057 (20130101)
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10243975 — Malware detector

US 10243975	Stavrou et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Materiel Command (AMC) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	George Mason Research Foundation, Inc. (Fairfax, Virginia)
ASSIGNEE(S)	George Mason Research Foundation, Inc. (Fairfax, Virginia)
INVENTOR(S)	Angelos Stavrou (Springfield, Virginia); Sushil Jajodia (Oakton, Virginia); Anup K. Ghosh (Centreville, Virginia); Rhandi Martin (St. James, Barbados); Charalampos Andrianakis (Crete, Greece)
ABSTRACT	A transparent proxy for malware detection includes a monitor module, a protocol determination module, a challenge generation module, a response determination module, and a data control module. The monitor module examines data originating from an application towards a remote server. The protocol determination module identifies the protocol type used for the data. The challenge generation module produces a challenge for the application based upon the protocol type, sends the challenge to the application, and maintains a state related to the data and the challenge. The response determination module makes a determination if an automatic non-interactive application response is received in response to the challenge from the application. The data control module allows the first data to continue to the remote server when the determination is valid. The data control module reports malware detection and blocks the data to continue to the remote server when the determination is invalid.
FILED	Tuesday, November 22, 2016
APPL NO	15/359026
ART UNIT	2439 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/566 (20130101) G06F 2221/2103 (20130101) G06F 2221/2119 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) H04L 63/145 (20130101) H04L 63/0884 (20130101) H04L 63/1416 (20130101) Original (OR) Class H04L 67/02 (20130101)
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10244655 — Two-phase liquid cooled electronics

US 10244655	Chainer et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Timothy Joseph Chainer (Putnam Valley, New York); Pritish Ranjan Parida (Fishkill, New York); Mark Delorman Schultz (Ossining, New York)
ABSTRACT	Techniques that facilitate two-phase liquid cooling electronics are provided. In one example, a server system comprises a two-phase cooling system and an air moving system. The two-phase cooling system reduces a first temperature of a first electronic component in the server system using a pump that circulates a coolant refrigerant through a two-phase refrigerant loop associated with the first electronic component, where first electronic component satisfies a first defined criterion. The air moving system reduces a second temperature of a second electronic component in the server system using one or more fans associated with the second electronic component, where the second electronic component satisfies a second defined criterion.
FILED	Monday, March 20, 2017
APPL NO	15/463231
ART UNIT	2835 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 1/20 (20130101) G06F 1/206 (20130101) G06F 1/3206 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20136 (20130101) H05K 7/20145 (20130101) H05K 7/20209 (20130101) H05K 7/20309 (20130101) H05K 7/20318 (20130101) H05K 7/20327 (20130101) H05K 7/20381 (20130101) Original (OR) Class H05K 7/20509 (20130101) H05K 7/20727 (20130101) H05K 7/20809 (20130101) H05K 7/20836 (20130101)
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RE047321 — Bulk amorphous refractory glasses based on the Ni(-Cu-)-Ti(-Zr)-Al alloy system

US RE47321	Johnson et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	William L. Johnson (Pasadena, California); Donghua Xu (Knoxville, Tennessee)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	William L. Johnson (Pasadena, California); Donghua Xu (Knoxville, Tennessee)
ABSTRACT	Bulk amorphous alloys based on quaternary Ni—Zr—Ti—Al alloy system, and the extension of this quaternary system to higher order alloys by the addition of one or more alloying elements, methods of casting such alloys, and articles made of such alloys are provided.
FILED	Thursday, September 22, 2011
APPL NO	13/240516
ART UNIT	3991 — Central Reexamination Unit (Chemical)
CURRENT CPC	Alloys C22C 1/002 (20130101) C22C 45/04 (20130101) Original (OR) Class
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Department of Energy (DOE)

10239009 — Continuously-operable flow stream processing system and method

US 10239009	Mitchell et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Mark A. Mitchell (Dublin, California); Brian Anderson (Lodi, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Mark A. Mitchell (Dublin, California); Brian Anderson (Lodi, California)
ABSTRACT	A continuously-operable flow stream processing system and method has two or more fluid processing media arranged in a fluid conduit network to provide alternate flow paths for a flow stream to be processed (e.g. filtered). Valves and other flow control devices, e.g. controller module and sensors, are used to redirect the flow stream from one or more service-needed fluid processing media to service-ready fluid processing media without taking the system offline to remove, repair, replace, clean in situ, or otherwise service the service-needed fluid processing media, so that the system may operate continuously to process the flow stream without stoppage. Redirection into alternative flow paths and media may be automatically implemented based on a predetermined threshold or trigger condition, such as may be detected by sensors directly or indirectly monitoring media condition.
FILED	Thursday, March 14, 2013
APPL NO	13/827855
ART UNIT	1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 46/18 (20130101) Original (OR) Class B01D 46/0058 (20130101)
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10239035 — Solar thermochemical reactor, methods of manufacture and use thereof and thermogravimeter

US 10239035	Klausner et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S)	James F. Klausner (Gainesville, Florida); Joerg Petrasch (Gainesville, Florida)
ABSTRACT	A solar thermochemical reactor includes an outer member, an inner member disposed within an outer member, wherein the outer member surrounds the inner member and wherein the outer member has an aperture for receiving solar radiation and wherein an inner cavity and an outer cavity are formed by the inner member and outer member and a reactive material capable of being magnetically stabilized wherein the reactive material is disposed in the outer cavity between the inner member and the outer member.
FILED	Tuesday, December 20, 2016
APPL NO	15/384837
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/42 (20130101) B01J 19/02 (20130101) B01J 19/087 (20130101) Original (OR) Class B01J 19/127 (20130101) B01J 2208/00451 (20130101) B01J 2219/085 (20130101) B01J 2219/0263 (20130101) B01J 2219/1203 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/042 (20130101) C01B 3/105 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 20/20 (20180501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/41 (20130101) Y02E 60/364 (20130101)
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10239036 — Solar thermochemical reactor, methods of manufacture and use thereof and thermogravimeter

US 10239036	Klausner et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (Gainesville, Florida)
INVENTOR(S)	James F. Klausner (Gainesville, Florida); Joerg Petrasch (Gainesville, Florida); Renwei Mei (Gainesville, Florida); Ayyoub Mehdizadeh Momen (Gainesville, Florida); Kyle Allen (Winter Garden, Florida); Fotouh A. Al-Raqom (Gainesville, Florida)
ABSTRACT	A solar thermochemical reactor includes an outer member, an inner member disposed within an outer member, wherein the outer member surrounds the inner member and wherein the outer member has an aperture for receiving solar radiation and wherein an inner cavity and an outer cavity are formed by the inner member and outer member and a reactive material capable of being magnetically stabilized wherein the reactive material is disposed in the outer cavity between the inner member and the outer member.
FILED	Monday, July 10, 2017
APPL NO	15/645223
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/42 (20130101) B01J 19/02 (20130101) B01J 19/087 (20130101) Original (OR) Class B01J 19/127 (20130101) B01J 2208/00451 (20130101) B01J 2219/085 (20130101) B01J 2219/0263 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/042 (20130101) C01B 3/105 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 20/20 (20180501) F24S 40/10 (20180501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/41 (20130101) Y02E 60/364 (20130101)
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10239046 — Nano-material

US 10239046	Menchhofer et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) National Security Complex and PANTEX Plant (Y-12) NNSA Critical Mission Site Operated by Consolidated Nuclear Security, LLC at Oak Ridge, TN (CNS) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee); UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee); UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Paul A. Menchhofer (Clinton, Tennessee); Roland D. Seals (Oak Ridge, Tennessee); Jane Y. Howe (Carmichael, California); Wei Wang (Oak Ridge, Tennessee)
ABSTRACT	A fluffy nano-material and method of manufacture are described. At 2000× magnification the fluffy nanomaterial has the appearance of raw, uncarded wool, with individual fiber lengths ranging from approximately four microns to twenty microns. Powder-based nanocatalysts are dispersed in the fluffy nanomaterial. The production of fluffy nanomaterial typically involves flowing about 125 cc/min of organic vapor at a pressure of about 400 torr over powder-based nano-catalysts for a period of time that may range from approximately thirty minutes to twenty-four hours.
FILED	Friday, November 21, 2014
APPL NO	14/549701
ART UNIT	1786 — Miscellaneous Articles, Stock Material
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/75 (20130101) B01J 23/745 (20130101) B01J 23/755 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/022 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/298 (20150115) Y10T 428/2991 (20150115)
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10239108 — Method for electro-hydraulic forming

US 10239108	Bonnen et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Ford Global Technologies, LLC (Dearborn, Michigan)
ASSIGNEE(S)	FORD GLOBAL TECHNOLOGIES, LLC (Dearborn, Michigan)
INVENTOR(S)	John Joseph Francis Bonnen (Milford, Michigan); Sergey Fedorovich Golovashchenko (Beverly Hills, Michigan)
ABSTRACT	One or more electro-hydraulic forming tools are operated by a press and provide formed parts to a trimming operation. A locking mechanism holds the die against the chamber during the electro-hydraulic forming (EHF) discharge. The lock may be a pin or clamp. One method of manufacturing an article includes providing three EHF tools that feed a single trimming press on a line. An alternative embodiment discloses a single EHF tool that supplies parts on a production line to an electro-hydraulic (EH) trimming tool. An electro-hydraulic pulse generator may be used to provide a stored charge to the EHF tool and the EH trimming tool.
FILED	Monday, September 21, 2015
APPL NO	14/859955
ART UNIT	3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 26/12 (20130101) Original (OR) Class
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10239152 — Friction stir welding bobbin tool

US 10239152	Carlson et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan)
ASSIGNEE(S)	GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan)
INVENTOR(S)	Blair E. Carlson (Ann Arbor, Michigan); Robert T. Szymanski (Saint Clair Township, Michigan); Yuri Hovanski (West Richland, Washington); Spyros P. Mellas (Waterford, Michigan); Kenneth Ross (West Richland, Washington)
ABSTRACT	A bobbin tool is disclosed that includes a top shoulder, a bottom shoulder, and an axial pin that extends between the top and bottom shoulders. The bottom shoulder has an annular shoulder end surface, a back surface opposite the annular shoulder end surface, and a side surface that joins the annular shoulder end surface and the back surface. One or more and radially-extending blades may be disposed on the side surface of the bottom shoulder and/or one or more axially-extending blades may be disposed on the back surface. The one or more blades provide the bobbin tool with an ability to friction stir weld a variable thickness workpiece assembly, axially plunged through the workpiece assembly along an axis of rotation of the bobbin tool, and/or be extracted through the workpiece assembly along an axis of rotation of the bobbin tool.
FILED	Wednesday, April 26, 2017
APPL NO	15/498204
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/1255 (20130101) Original (OR) Class B23K 20/1265 (20130101)
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10239368 — Air maintenance tire and valve assembly

US 10239368	Benedict et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	The Goodyear Tire and Rubber Company (Akron, Ohio)
ASSIGNEE(S)	The Goodyear Tire and Rubber Company (Akron, Ohio)
INVENTOR(S)	Robert Leon Benedict (Tallmadge, Ohio); Robert Allen Losey (Kent, Ohio); Thulasiram Gobinath (Hudson, Ohio)
ABSTRACT	A self-inflating tire assembly includes an air tube mounted within a tire sidewall groove. The air tube is in contacting engagement with opposite angled groove surfaces surrounding the air tube. A segment of the air tube is flattened from an expanded diameter to a flat diameter by bending and compression of the groove in a rolling tire footprint to force air evacuated from the flattened segment along a tube air passageway. A tube is positioned within the groove, wherein the tube has a circular cross-sectional shape and an outside diameter D, and the groove does not have a circular cross-sectional shape, wherein said groove has a width W and a length L, wherein D is greater than W.
FILED	Thursday, December 11, 2014
APPL NO	14/567446
ART UNIT	3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Vehicle Tyres Tyre Inflation; Tyre Changing or Repairing; Repairing, or Connecting Valves To, Inflatable Elastic Bodies in General; Devices or Arrangements Related to Tyres B60C 23/001 (20130101) B60C 23/10 (20130101) B60C 23/12 (20130101) Original (OR) Class
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10239978 — Redox active colloidal particles for flow batteries

US 10239978	Moore et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Jeffrey S. Moore (Savoy, Illinois); Joaquin Rodriguez-Lopez (Urbana, Illinois); Nagarjuna Gavvalapalli (Urbana, Illinois); Elena Montoto (Champaign, Illinois); Jingshu Hui (Urbana, Illinois)
ABSTRACT	The invention provides a redox flow battery comprising a microporous or nanoporous size-exclusion membrane, wherein one cell of the battery contains a redox-active colloidal particle dispersed in a non-aqueous solvent. The redox flow battery provides enhanced ionic conductivity across the electrolyte separator and reduced redox-active species crossover, thereby improving the performance and enabling widespread utilization of the battery. Redox active colloidal particles (RACs) were prepared, analyzed, and were found to be highly effective redox species for use in redox flow batteries.
FILED	Thursday, January 19, 2017
APPL NO	15/410499
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/30 (20130101) C08F 8/30 (20130101) C08F 8/30 (20130101) C08F 8/30 (20130101) C08F 12/18 (20130101) C08F 12/26 (20130101) C08F 12/32 (20130101) C08F 112/14 (20130101) C08F 112/14 (20130101) C08F 212/14 (20130101) C08F 212/14 (20130101) C08F 212/14 (20130101) C08F 212/36 (20130101) C08F 214/14 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/02 (20130101) H01M 8/20 (20130101) H01M 8/188 (20130101) H01M 2300/0025 (20130101) H01M 2300/0028 (20130101)
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10240011 — Multifunctional curing agents and their use in improving strength of composites containing carbon fibers embedded in polymeric matrix

US 10240011	Vautard et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Frederic Vautard (Knoxville, Tennessee); Soydan Ozcan (Oak Ridge, Tennessee)
ABSTRACT	A functionalized carbon fiber having covalently bound on its surface a sizing agent containing epoxy groups, at least some of which are engaged in covalent bonds with crosslinking molecules, wherein each of said crosslinking molecules possesses at least two epoxy-reactive groups and at least one free functional group reactive with functional groups of a polymer matrix in which the carbon fiber is to be incorporated, wherein at least a portion of said cros slinking molecules are engaged, via at least two of their epoxy-reactive groups, in crosslinking bonds between at least two epoxy groups of the sizing agent. Composites comprised of these functionalized carbon fibers embedded in a polymeric matrix are also described. Methods for producing the functionalized carbon fibers and composites thereof are also described.
FILED	Monday, February 27, 2017
APPL NO	15/443551
ART UNIT	1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/06 (20130101) Original (OR) Class C08J 2367/06 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 14/36 (20130101) D06M 15/55 (20130101) D06M 15/263 (20130101) D06M 15/273 (20130101) D06M 2101/40 (20130101) D06M 2200/40 (20130101) D06M 2400/01 (20130101)
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10240067 — Curable polysiloxane compositions and slippery materials and coatings and articles made therefrom

US 10240067	Kim et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Adaptive Surface Technologies, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	Adaptive Surface Technologies (Cambridge, Massachusetts)
INVENTOR(S)	Philseok Kim (Waltham, Massachusetts); Teluka Pasan Galhenage (Chestnut Hill, Massachusetts); Joseph Lomakin (Alington, Massachusetts)
ABSTRACT	The present teachings generally provide curable polysiloxane compositions including a base resin including a MQ vinyl siloxane. Articles of manufacture including the curable polysiloxane compositions and slippery coatings and materials also are provided. The compositions may be used to provide slippery, lubricious, or repellent materials and coatings and may provide anti-fouling function. The compositions can provide anti-fouling or foul-release function on open surfaces, internal surfaces, membranes; to provide pinning free or low contact angle hysteresis surfaces; to provide homogeneous interface to suppress nucleation; to provide a barrier layer such as anti-corrosion; to provide anti-stain, anti-smudge, anti-fingerprint, anti-soil function.
FILED	Monday, April 23, 2018
APPL NO	15/959750
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 9/04 (20130101) B32B 27/283 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/12 (20130101) C08G 77/16 (20130101) C08G 77/20 (20130101) Compositions of Macromolecular Compounds C08L 83/00 (20130101) C08L 83/00 (20130101) C08L 83/04 (20130101) C08L 83/04 (20130101) C08L 83/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1675 (20130101) C09D 183/04 (20130101) Original (OR) Class
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10240158 — Compositions and methods for making selenocysteine containing polypeptides

US 10240158	Soll et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF)
APPLICANT(S)	Yale University (New Haven, Connecticut)
ASSIGNEE(S)	Yale University (New Haven, Connecticut)
INVENTOR(S)	Dieter Soll (Guilford, Connecticut); Caroline Aldag (New Haven, Connecticut); Michael Hohn (Scotch Plains, New Jersey); Corwin Miller (New Haven, Connecticut)
ABSTRACT	Non-naturally occurring tRNA^Secand methods of using them for recombinant expression of proteins engineered to include one or more selenocysteine residues are disclosed. The non-naturally occurring tRNA^Seccan be used for recombinant manufacture of selenocysteine containing polypeptides encoded by mRNA without the requirement of an SECIS element. In some embodiments, selenocysteine containing polypeptides are manufactured by co-expressing a non-naturally occurring tRNA^Seca recombinant expression system, such as E. coli, with SerRS, EF-Tu, SelA, or PSTK and SepSecS, and an mRNA with at least one codon that recognizes the anticodon of the non-naturally occurring tRNA^Sec.
FILED	Tuesday, July 05, 2016
APPL NO	15/202194
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/67 (20130101) C12N 15/70 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101)
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10240163 — Increasing the content of long chain fatty acids in seed oil

US 10240163	Wang et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Basic Energy Sciences (BES) Energy Frontier Research Centers (EFRC) Center for Advanced Biofuel Systems (CABS) Materials Sciences and Engineering Division (MSE) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI) Division of Molecular and Cellular Biosciences (MCB) U.S. State Government State of Kansas Kansas Lipidomics Research Center (KLRC)
APPLICANT(S)	Donald Danforth Plant Science Center (St. Louis, Missouri); The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S)	Donald Danforth Plant Science Center (St. Louis, Missouri); The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S)	Xuemin Wang (St. Louis, Missouri); Maoyin Li (St. Louis, Missouri)
ABSTRACT	Provided are plants that express, or overexpress, a pPLAIIIδ protein. Constitutive or seed-specific expression of pPLAIIIδ protein in Arabidopsis increases seed oil content, the amount of C20 and C22 fatty acids, and the amount of C56, C58, and C60 triacylglycerols, effectively resulting in significantly higher oil yield per plant. Use of pPLAIIIδ is therefore an effective biotechnological tool to significantly increase plant yield, including oil, and the amount of high value long chain fatty acids in agricultural and horticultural crops, especially oilseed crops.
FILED	Friday, September 25, 2015
APPL NO	14/866125
ART UNIT	1662 — Plants
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 69/604 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/20 (20130101) C12N 15/8247 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6463 (20130101) Enzymes C12Y 301/01 (20130101)
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10240177 — Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods

US 10240177	Thompson et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S)	David N. Thompson (Idaho Falls, Idaho); William A. Apel (Jackson, Wyoming); Vicki S. Thompson (Idaho Falls, Idaho); David W. Reed (Idaho Falls, Idaho); Jeffrey A. Lacey (Idaho Falls, Idaho); Emily D. Henriksen (Carey, North Carolina)
ABSTRACT	Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of at least partially degrading, cleaving, or removing polysaccharides, lignocellulose, cellulose, hemicellulose, lignin, starch, chitin, polyhydroxybutyrate, heteroxylans, glycosides, xylan-, glucan-, galactan-, or mannan-decorating groups using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius.
FILED	Friday, February 16, 2018
APPL NO	15/898378
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/18 (20130101) C12N 9/80 (20130101) C12N 9/88 (20130101) C12N 9/248 (20130101) C12N 9/1051 (20130101) C12N 9/2402 (20130101) C12N 9/2408 (20130101) C12N 9/2428 (20130101) C12N 9/2434 (20130101) C12N 9/2437 (20130101) C12N 9/2445 (20130101) C12N 9/2465 (20130101) C12N 9/2471 (20130101) C12N 9/2482 (20130101) C12N 9/2494 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/00 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) Original (OR) Class Enzymes C12Y 204/0102 (20130101) C12Y 301/01001 (20130101) C12Y 301/01006 (20130101) C12Y 301/01073 (20130101) C12Y 301/02004 (20130101) C12Y 302/0102 (20130101) C12Y 302/01008 (20130101) C12Y 302/01015 (20130101) C12Y 302/01021 (20130101) C12Y 302/01022 (20130101) C12Y 302/01037 (20130101) C12Y 302/01055 (20130101) C12Y 302/01078 (20130101) C12Y 302/01091 (20130101) C12Y 302/01131 (20130101) C12Y 302/01133 (20130101) C12Y 302/01139 (20130101) C12Y 305/01 (20130101) C12Y 402/01007 (20130101) C12Y 402/01008 (20130101)
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10240180 — Multiplexed screening of enzyme activities using nanostructure-initiator mass spectrometry

US 10240180	Northen et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	Trent R. Northen (Walnut Creek, California); Wolfgang E. Reindl (Berkeley, California); Kai Deng (Albany, California); Seema Singh (Fremont, California); Anup K. Singh (Danville, California); Xiaoliang Cheng (Albany, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); National Technology and Engineering Solutions of Sandia, LLC (Livermore, California)
INVENTOR(S)	Trent R. Northen (Walnut Creek, California); Wolfgang E. Reindl (Berkeley, California); Kai Deng (Albany, California); Seema Singh (Fremont, California); Anup K. Singh (Danville, California); Xiaoliang Cheng (Albany, California)
ABSTRACT	Disclosed herein are methods, compositions and systems for analyzing and detecting enzyme activity. For examples, methods, compositions and systems for parallel detection and analysis of enzymatic activities of enzymes in complex biological mixtures are provided.
FILED	Wednesday, February 01, 2012
APPL NO	13/363695
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2560/00 (20130101)
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10240486 — Harmonic adsorption recuperative power systems and methods

US 10240486	McGrail et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington); Rockwell Collins Inc. (Cedar Rapids, Iowa); EthosGen, LLC (Wilkes-Barre, Pennsylvania)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington); Rockwell Collins Inc. (Cedar Rapids, Iowa); Ethosgen, LLC (Wilkes-Barre, Pennsylvania)
INVENTOR(S)	B. Peter McGrail (Pasco, Washington); Radha Kishan Motkuri (Richland, Washington); Jeromy J. Jenks (Hines, Oregon); Paul Roege (Wilkes-Barre, Pennsylvania); William Abrams (Simpsonville, South Carolina)
ABSTRACT	A new power generation thermodynamic cycle is described that eliminates need for bulk liquid condensation and vaporization steps required in conventional ORC power systems. An exemplary harmonic adsorption recuperative power cycle system offers more efficient power generation as compared with conventional ORC systems. A multibed adsorption system is used to provide thermal compression for the cycle. An adsorption compressor contains a sorbent with strong adsorption affinity for the working fluid in the pores while well outside the P-T conditions needed to condense the liquid phase, allowing the adsorption compressor to reduce operating pressure exiting the expander.
FILED	Tuesday, June 27, 2017
APPL NO	15/634690
ART UNIT	3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 13/006 (20130101) Original (OR) Class F01K 25/00 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 37/00 (20130101)
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10240660 — Safe assembly and installation of a flywheel

US 10240660	Sun et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Amber Kinetics, Inc. (Union City, California)
ASSIGNEE(S)	Amber Kinetics, Inc. (Union City, California)
INVENTOR(S)	Eric Sun (Union City, California); Daniel Bakholdin (Newbury Park, California); Edward Young Chiao (San Jose, California); Matthew Brandon Garten (Mountain View, California); Mike M. He (San Jose, California); Mark J. Holloway (Mountain View, California); Seth R. Sanders (Berkeley, California); Matthew K. Senesky (Berkeley, California); Alan Michael Sledd (San Francisco, California); Peter Thomas Tennessen (Oakland, California)
ABSTRACT	A flywheel device includes structures allowing the flywheel system to be assembled offsite, transported safely, and installed with relatively few steps. The flywheel includes a rotor and a housing enclosing the rotor, where the housing includes a bottom plate, a top plate and side walls. The bottom plate and the top plate each includes a hole aligned with the center axis of the rotor. The flywheel also includes multiple bearing housings substantially covering the holes of the bottom plate and the top plate that are aligned to the center axis of the rotor. The flywheel also includes posts that physically contact the primary rotational mass of the rotor to prevent motion of the rotor during transport of the flywheel system. Some or all of these posts may be repositioned or removed during installation so that the rotor can spin freely.
FILED	Thursday, June 23, 2016
APPL NO	15/191398
ART UNIT	3656 — Material and Article Handling
CURRENT CPC	Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 41/04 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 15/315 (20130101) Original (OR) Class Gearing F16H 2057/0093 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/16 (20130101)
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10240875 — Active cryogenic electronic envelope

US 10240875	Turqueti et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	Marcos de Azambuja Turqueti (El Sobrante, California); Robert Alan Albright (Oakland, California); Soren O. Prestemon (Martinez, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Marcos de Azambuja Turqueti (El Sobrante, California); Robert Alan Albright (Oakland, California); Soren O. Prestemon (Martinez, California)
ABSTRACT	A data acquisition module is disclosed for use with electronic components such as superconductive magnets wherein the electronic components and the data acquisition module may reside inside a cryostat. The data acquisition module allows conventional electronic technologies to work inside cryostats at cryogenic temperatures as low as 4° K. This is achieved by management of heat inside the module to keep the module operating at a temperature above the cryogenic temperature. This approach avoids the difficulties that arise from changes in carrier mobility in semiconductors operating at deep cryogenic temperatures. A cryogenic system comprises a cryostat containing a cryogenic fluid and at least one sensor, and a data acquisition module located within the cryostat, the module in communication with the at least one sensor to acquire data, wherein the module comprises a thermal package, a conditioning and digitizing electronic module, a controller module, a power module, and a thermal management module.
FILED	Thursday, July 02, 2015
APPL NO	14/790614
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 3/085 (20130101) F17C 13/02 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/00 (20130101) Original (OR) Class F28F 2013/006 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 5/0213 (20130101)
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10240988 — Fully automated calibration for acoustic pyrometry

US 10240988	Yan et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Siemens Energy, Inc. (Orlando, Florida)
ASSIGNEE(S)	SIEMENS ENERGY, INC. (Orlando, Florida)
INVENTOR(S)	Michelle xiaohong Yan (Princeton, New Jersey); Heiko Claussen (North Brunswick, New Jersey); Upul P. DeSilva (Oviedo, Florida); Justinian Rosca (West Windsor, New Jersey); Tong Fang (Morganville, New Jersey); Nancy H. Ulerich (Longwood, Florida)
ABSTRACT	A method of calibrating transceiver positions inside an acoustic pyrometry measuring vessel that contains a plurality of transceivers, includes determining (40) a speed of sound in the acoustic pyrometry measuring vessel from a temperature and gas composition of a gas inside the acoustic pyrometry measuring vessel, acquiring (41) time-of-flight (TOFs) Δti_,jmeasurements from a plurality of pairs i,j of transceivers inside the acoustic pyrometry measuring vessel, estimating (42) a radius of the acoustic pyrometry measuring vessel from an average of the acquired TOF measurements, and using (43) an estimated radius of the acoustic pyrometry measuring vessel to estimate errors Δθj of displacement angles of the transceivers.
FILED	Thursday, May 29, 2014
APPL NO	14/894010
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/24 (20130101) G01K 13/02 (20130101) G01K 15/005 (20130101) Original (OR) Class G01K 2013/024 (20130101) G01K 2205/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2291/02881 (20130101)
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10240998 — Determining a location and size of a gas source with a spectrometer gas monitor

US 10240998	Prasad et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia); The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia); The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S)	Kuldeep Prasad (Vienna, Virginia); Caroline Alden (Boulder, Colorado); Gregory Brian Rieker (Boulder, Colorado); Robert James Wright (Boulder, Colorado); Sean Coburn (Longmont, Colorado)
ABSTRACT	A process for determining a location and size of a gas source within an area with a spectrometer gas monitor includes: providing the spectrometer gas monitor; performing fence line monitoring of the area with the spectrometer gas monitor; collecting spectroscopic data over multiple open paths around the area with the spectrometer gas monitor; measuring atmospheric conditions along gas inflows and gas outflows of the area; subtracting a background for a selected gas from the spectroscopic data; applying a boundary constraint to the spectroscopic data; determining an atmospheric concentration of air entering the area; applying bootstrapping to the spectroscopic data; applying zero minimum elimination to the spectroscopic data; and producing inversion data from the spectroscopic data to determine the location and size of the gas source within the area.
FILED	Tuesday, October 10, 2017
APPL NO	15/729079
ART UNIT	2857 — Printing/Measuring and Testing
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/16 (20130101) Original (OR) Class G01M 3/22 (20130101) G01M 3/202 (20130101)
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10241018 — Wear test apparatus

US 10241018	Zafred et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Department of Energy (DOE) Knolls Atomic Power Laboratory (KAPL) National Nuclear Security Administration (NNSA) Naval Nuclear Laboratory (NNL)
APPLICANT(S)	United States Department of Energy (Washington, District of Columbia)
ASSIGNEE(S)	U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S)	Paolo R. Zafred (Murrysville, Pennsylvania); William H. Howland (Wexford, Pennsylvania)
ABSTRACT	Disclosed is an exemplary test apparatus having an autoclave head, a fretting mechanism connected on a first end to a first side of the autoclave head, a load train operably connected with a first end of the fretting mechanism, an autoclave adapter connected on a first side to a second side of the autoclave head, and a force balance assembly connected to a second side of the autoclave head and configured to equalize a pressure acting on the load train. Certain exemplary embodiments include an upper plate, a plurality of upper tie rods connected to a first side of the upper plate and a second side of the autoclave adapter, a lower plate, a plurality of lower tie rods connected to the first side of the autoclave head and a first side of the lower plate, and a pressure vessel sealingly connected to the first side of the autoclave head.
FILED	Thursday, October 27, 2016
APPL NO	15/335542
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/32 (20130101) G01N 3/56 (20130101) Original (OR) Class G01N 2203/0005 (20130101) G01N 2203/0008 (20130101) G01N 2203/023 (20130101) G01N 2203/0222 (20130101) G01N 2203/0224 (20130101) G01N 2203/0232 (20130101)
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10241045 — Spectrally encoded microbeads and methods and devices for making and using same

US 10241045	Baxter et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Brian Cullen Baxter (Santa Clara, California); Joseph L. Derisi (San Francisco, California); Polly M. Fordyce (San Francisco, California); Rachel E. Gerver (Oakland, California); Rafael Gòmez-Sjöberg (Menlo Park, California); Brett A. Helms (San Francisco, California); Kurt S. Thorn (San Francisco, California); Ronald N. Zuckermann (El Cerrito, California)
ABSTRACT	Spectrally encoded microbeads and methods and devices for making and using spectrally encoded microbeads are provided. The disclosed methods and devices facilitate the preparation and use of microbeads containing multiple lanthanide nanoparticles, which microbeads have uniquely identifiable spectral codes. The disclosed microbeads, and the methods and devices for making and using same, find use in multiplexing and high-throughput biomarker analysis.
FILED	Thursday, August 22, 2013
APPL NO	14/420320
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 3/0861 (20130101) B01F 5/061 (20130101) B01F 13/0059 (20130101) B01F 13/0062 (20130101) B01F 13/1027 (20130101) B01F 2005/0623 (20130101) B01F 2005/0636 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/44 (20130101) C08F 222/385 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) Original (OR) Class G01N 33/585 (20130101) G01N 33/587 (20130101) G01N 2201/061 (20130101) G01N 2458/40 (20130101)
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10241058 — Systems and methods for quality control of a periodic structure

US 10241058	Maznev et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Alexei Maznev (Allston, Massachusetts); Keith A. Nelson (Newton, Massachusetts); Abdelhak Bensaoula (Houston, Texas); Jateen S. Gandhi (Houston, Texas); Donna Washington Stokes (Friendswood, Texas); Rebecca Lynne Forrest (Houston, Texas); Hyun Doug Shin (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Alexei Maznev (Allston, Massachusetts); Keith A. Nelson (Newton, Massachusetts); Abdelhak Bensaoula (Houston, Texas); Jateen S. Gandhi (Houston, Texas); Donna Washington Stokes (Friendswood, Texas); Rebecca Lynne Forrest (Houston, Texas); Hyun Doug Shin (Cambridge, Massachusetts)
ABSTRACT	Quality control of a periodic structure is performed using the damping rate of acoustic waves generated in the periodic structure. In this technique, an excitation light beam illuminates the first layer in the periodic structure to excite an acoustic wave. Possible irregularities in the periodic structure can scatter the acoustic wave, thereby increasing the damping rate of the acoustic wave. A sequence of probe light beams illuminates the periodic structure to measure the acoustic wave as a function of time to generated a temporal signal representing the damping rate of the acoustic signal. The acquired damping rate is employed to evaluate the quality of the periodic structure.
FILED	Wednesday, July 05, 2017
APPL NO	15/641724
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1717 (20130101) G01N 21/8422 (20130101) G01N 21/9501 (20130101) G01N 21/9515 (20130101) Original (OR) Class G01N 29/38 (20130101) G01N 29/46 (20130101) G01N 29/2418 (20130101) G01N 2021/8438 (20130101) G01N 2291/0231 (20130101) G01N 2291/0237 (20130101) G01N 2291/2697 (20130101) G01N 2291/02854 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/002 (20130101)
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10241275 — Optical fiber connector ferrule assembly having dual reflective surfaces for beam expansion and expanded beam connector incorporating same

US 10241275	Li et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	NANOPRECISION PRODUCTS, INC. (El Segundo, California)
ASSIGNEE(S)	NANOPRECISION PRODUCTS, INC. (Camarillo, California)
INVENTOR(S)	Shuhe Li (Pasadena, California); Robert Ryan Vallance (Newbury Park, California); Rand D. Dannenberg (Newbury Park, California); Matthew Gean (Camarillo, California); Gregory L. Klotz (La Verne, California)
ABSTRACT	An expanded beam ferrule includes a first ferrule halve having first reflective surfaces and a second ferrule halve having second reflective surfaces, which together retain optical fibers. The pair of reflective surfaces output collimated light parallel to the mid-plane of the ferrule. An external sleeve aligns the external surface of two similar ferrules, with corresponding second reflective surfaces of the ferrules facing each other. Output light from an optical fiber held in one ferrule is bent twice by the pair of reflective surfaces, with beam divergence after the first bent, and collimation after the second bent. The collimated light is transmitted to the facing second reflective surface in a facing second ferrule aligned by the sleeve, which is subject to optical reshaping in reverse to that undertaken in the first ferrule, so as to converge and focus light to input to the optical fiber held in the other ferrule.
FILED	Thursday, August 17, 2017
APPL NO	15/680204
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/383 (20130101) G02B 6/3818 (20130101) Original (OR) Class G02B 6/3839 (20130101) G02B 6/3849 (20130101) G02B 6/3865 (20130101) G02B 6/3874 (20130101) G02B 6/3885 (20130101) G02B 6/3887 (20130101) G02B 6/3893 (20130101) G02B 6/4214 (20130101) G02B 6/4403 (20130101)
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10242193 — Method of resource-limited device and device class identification using system and function call tracing techniques, performance, and statistical analysis

US 10242193	Babun et al.
FUNDED BY	Department of Energy (DOE) Office of Electricity (DOE-OE)
APPLICANT(S)	Leonardo Babun (Miami, Florida); Hidayet Aksu (Miami, Florida); A. Selcuk Uluagac (Miami, Florida)
ASSIGNEE(S)	The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S)	Leonardo Babun (Miami, Florida); Hidayet Aksu (Miami, Florida); A. Selcuk Uluagac (Miami, Florida)
ABSTRACT	Methods for cyber physical systems device classification are provided. A method can include receiving system and function calls and parameters and a device performance index from an unknown CPS device and a device performance index of similar class of CPS devices, calculating an autocorrelation value between different realizations of the system and function calls and parameters of the known CPS device, determining whether the autocorrelation value is greater than a threshold amount, and storing the system and function calls and parameters and the device performance characteristics of the known CPS device in the database. A method can also include calculating a correlation between system and function calls and parameters of an unknown CPS device and known CPS devices classes included in the database, as well as determining whether the maximum correlation is also greater than a threshold amount.
FILED	Thursday, January 04, 2018
APPL NO	15/862044
ART UNIT	2437 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/57 (20130101) Original (OR) Class G06F 21/577 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0876 (20130101)
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10242770 — Long length high temperature superconducting wires with uniform ion implanted pinning microstructures

US 10242770	Rupich et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) Brookhaven Science Associates, LLC (BSA) Office of Science (DOE-SC) Brookhaven National Laboratory (BNL) Federally Funded Research and Development Center (FFRDC) Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S)	American Superconductor Corporation (Devens, Massachusetts); Brookhaven Science Associates, LLC (Upton, New York)
ASSIGNEE(S)	American Superconductor Corporation (Ayer, Massachusetts); Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S)	Martin W. Rupich (Framingham, Massachusetts); Srivatsan Sathyamurthy (Westford, Massachusetts); Qiang Li (Setauket, New York); Vyacheslav F. Solovyov (Rocky Point, New York)
ABSTRACT	A method for producing a long length high temperature superconductor wire, includes providing a substrate, having a surface with a length of at least 50 meters and a width. The surface supports a biaxially textured high temperature superconducting layer and the biaxially textured high temperature superconducting layer has a length and a width corresponding to the length and width of the surface of the substrate. The method includes irradiating the biaxially textured high temperature superconductor layer with an ion beam impinging uniformly along the length and across the width of the biaxially textured high temperature superconductor layer to produce a uniform distribution of pinning microstructures in the biaxially textured high temperature superconductor layer.
FILED	Thursday, August 25, 2016
APPL NO	15/246739
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/04 (20130101) Original (OR) Class H01B 13/003 (20130101) H01B 13/0016 (20130101) H01B 13/0036 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/249 (20130101) H01L 39/2483 (20130101)
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10242806 — Solar fuels generator

US 10242806	Lewis et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Joint Center for Artificial Photosynthesis (JCAP) National Aeronautics and Space Administration (NASA)
APPLICANT(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S)	THE CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Nathan S. Lewis (La Canada Flintridge, California); Joshua M. Spurgeon (Los Angeles, California); William C. West (South Pasadena, California); Chengxiang Xiang (Pasadena, California)
ABSTRACT	The solar fuels generator includes an ionically conductive separator between a gaseous first phase and a second phase. A photoanode uses one or more components of the first phase to generate cations during operation of the solar fuels generator. A cation conduit is positioned provides a pathway along which the cations travel from the photoanode to the separator. The separator conducts the cations. A second solid cation conduit conducts the cations from the separator to a photocathode.
FILED	Thursday, May 17, 2018
APPL NO	15/982832
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/003 (20130101) C25B 9/08 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/20 (20130101) Original (OR) Class
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10242856 — Systems and methods for relay ionization

US 10242856	Cooks et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	PURDUE RESEARCH FOUNDATION (West Layfette, Indiana)
INVENTOR(S)	Robert Graham Cooks (West Lafayette, Indiana); Anyin Li (West Lafayette, Indiana); Adam Hollerbach (West Lafayette, Indiana)
ABSTRACT	The invention generally relates to systems and methods for relay ionization of a sample. In certain aspects, the invention provides systems that include an ion source that generates ions, a sample emitter configured to hold a sample, and a mass spectrometer. The system is configured such that the ions generated by the ion source are directed to interact with the sample emitter, thereby causing the sample to be discharged from the sample emitter and into the mass spectrometer.
FILED	Wednesday, March 09, 2016
APPL NO	15/556401
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/00 (20130101) H01J 49/04 (20130101) H01J 49/165 (20130101) H01J 49/167 (20130101) H01J 49/0409 (20130101) Original (OR) Class
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10243095 — Moldable photovoltaic solar cell module

US 10243095	Nelson et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Jeffrey S. Nelson (Albuquerque, New Mexico); Michael Hibbs (Albuquerque, New Mexico); Gregory N. Nielson (Lehi, Utah); Murat Okandan (Edgewood, New Mexico); Jose Luis Cruz-Campa (Albuquerque, New Mexico); Paul J. Resnick (Albuquerque, New Mexico); Carlos Anthony Sanchez (Belen, New Mexico); Vipin P. Gupta (Glenview, Illinois); Peggy J. Clews (Tigeras, New Mexico)
ABSTRACT	A method is provided for making a molded photovoltaic module. The module includes a flexible polymeric flex-circuit substrate having an electrically conductive printed wiring pattern and solder pads defined on it. Small photovoltaic cells are affixed to the flex-circuit substrate by back-surface contacts in electrical contact with the solder pads. At least one thermoformable polymeric film is joined to the flex-circuit substrate. Each said solder pad comprises a solder composition that, after an initial melt, has a melting point that lies above at least a portion of the temperature range for thermoforming the polymeric film.
FILED	Thursday, July 19, 2018
APPL NO	16/040190
ART UNIT	2898 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/048 (20130101) H01L 31/0465 (20141201) H01L 31/0512 (20130101) H01L 31/0516 (20130101) Original (OR) Class H01L 31/022441 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/40 (20141201) H02S 30/20 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) Y02E 10/547 (20130101)
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10243105 — Group-III nitride devices and systems on IBAD-textured substrates

US 10243105	Matias
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	iBeam Materials, Inc. (Santa Fe, New Mexico)
ASSIGNEE(S)	iBeam Materials, Inc. (Santa Fe, New Mexico)
INVENTOR(S)	Vladimir Matias (Santa Fe, New Mexico)
ABSTRACT	A multilayer structure including a hexagonal epitaxial layer, such as GaN or other group III-nitride (III-N) semiconductors, a <111> oriented textured layer, and a non-single crystal substrate, and methods for making the same. The textured layer has a crystalline alignment preferably formed by the ion-beam assisted deposition (IBAD) texturing process and can be biaxially aligned. The in-plane crystalline texture of the textured layer is sufficiently low to allow growth of high quality hexagonal material, but can still be significantly greater than the required in-plane crystalline texture of the hexagonal material. The IBAD process enables low-cost, large-area, flexible metal foil substrates to be used as potential alternatives to single-crystal sapphire and silicon for manufacture of electronic devices, enabling scaled-up roll-to-roll, sheet-to-sheet, or similar fabrication processes to be used. The user is able to choose a substrate for its mechanical and thermal properties, such as how well its coefficient of thermal expansion matches that of the hexagonal epitaxial layer, while choosing a textured layer that more closely lattice matches that layer. Electronic devices such as LEDs can be manufactured from such structures. Because the substrate can act as both a reflector and a heat sink, transfer to other substrates, and use of external reflectors and heat sinks, is not required, greatly reducing costs. Large area devices such as light emitting strips or sheets may be fabricated using this technology.
FILED	Friday, August 11, 2017
APPL NO	15/675598
ART UNIT	2896 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/18 (20130101) H01L 33/32 (20130101) Original (OR) Class H01L 33/644 (20130101)
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10243127 — Systems and methods of fabrication and use of NbFeSb P-type half-heusler thermoelectric materials

US 10243127	Ren et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	University of Houston System (Houston, Texas)
ASSIGNEE(S)	UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S)	Zhifeng Ren (Houston, Texas); Ran He (Houston, Texas)
ABSTRACT	Discussed herein are half-Heusler thermoelectric materials including niobium, iron, antimony, and titanium that are formed by ball-milling and hot-pressing the ball-milled power to obtain various thermoelectric properties and an average grain size above 1 μm.
FILED	Tuesday, August 29, 2017
APPL NO	15/689344
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/14 (20130101) B22F 2009/043 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) Alloys C22C 1/04 (20130101) C22C 1/045 (20130101) C22C 12/00 (20130101) C22C 33/0278 (20130101) C22C 38/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/18 (20130101) H01L 35/20 (20130101) Original (OR) Class H01L 35/34 (20130101)
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10243202 — Polymers for use as protective layers and other components in electrochemical cells

US 10243202	Fleischmann et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Sion Power Corporation (Tucson, Arizona); BASF SE (Ludwigshafen, Germany)
ASSIGNEE(S)	Sion Power Corporation (Tucson, Arizona); BASF SE (Ludwigshafen, Germany)
INVENTOR(S)	Sven Fleischmann (Ludwigshafen, Germany); Tobias Petsch (Mörschied, Germany); Andrea Misske (Speyer, Germany); Ruediger Schmidt (Paderborn, Germany); Veronika G. Viner (Tucson, Arizona); Bala Sankaran (Tucson, Arizona)
ABSTRACT	Electrode structures and electrochemical cells are provided. The electrode structures and/or electrochemical cells described herein may include one or more protective layers comprising a polymer layer and/or a gel polymer electrolyte layer. The polymer layer may be formed from the copolymerization of an olefinic monomer comprising at least one electron withdrawing group and an olefinic comonomer comprising at least one electron donating group. Methods for forming polymer layers are also provided.
FILED	Thursday, October 31, 2013
APPL NO	14/068333
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/145 (20130101) H01M 2/1653 (20130101) H01M 4/13 (20130101) H01M 4/139 (20130101) Original (OR) Class H01M 4/366 (20130101) H01M 4/622 (20130101) H01M 4/628 (20130101) H01M 10/0565 (20130101) H01M 2300/0085 (20130101)
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10243206 — High capacity and stable cathode materials

US 10243206	Zheng et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Jianming Zheng (Richland, Washington); Jiguang Zhang (Richland, Washington); Pengfei Yan (Richland, Washington); Chongmin Wang (Richland, Washington); Wengao Zhao (Richland, Washington); Shuru Chen (Richland, Washington); Wu Xu (Richland, Washington)
ABSTRACT	High energy density cathode materials, such as LiNi_XMn_YCo_ZO2 (NMC) cathode materials, with improved discharge capacity (hence energy density) and enhanced cycle life are described. A solid electrolyte, such as lithium phosphate infused inside of secondary particles of the cathode material demonstrates significantly enhanced structural integrity without significant or without any observable particle cracking occurring during charge/discharge processes, showing high capacity retention of more than 90% after 200 cycles at room temperature. In certain embodiments the disclosed cathode materials (and cathodes made therefrom) are formed using nickel-rich NMC and/or are used in a battery system with a non-aqueous dual-Li salt electrolytes.
FILED	Tuesday, May 16, 2017
APPL NO	15/597025
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/364 (20130101) Original (OR) Class H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/5825 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2004/028 (20130101) H01M 2300/0037 (20130101)
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10243240 — Electrolytes and metal hydride batteries

US 10243240	Young et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	BASF Corporation (Florham Park, New Jersey)
ASSIGNEE(S)	BASF Corporation (Florham Park, New Jersey)
INVENTOR(S)	Kwo Young (Troy, Michigan); Jean Nei (Southgate, Michigan); Diana Wong (Sterling Heights, Michigan); Wentao Li (Solon, Ohio); Lixin Wang (Ypsilanti, Michigan)
ABSTRACT	A metal hydride battery comprising at least one negative electrode, at least one positive electrode, a casing having said electrodes positioned therein and an electrolyte composition, where the electrolyte composition comprises an ionic compound selected from the group consisting of protic acids, protic ammonium compounds, protic oxonium compounds, aprotic ammonium compounds, aprotic oxonium compounds, aprotic phosphonium compounds and alkali or alkali earth metal salts; or where the electrolyte composition comprises an ionic compound selected from the group consisting of alkali or alkali earth metal hydroxides and alkali or alkali earth metal alkoxides and an organic solvent; or where the electrolyte composition comprises an alkali metal hydroxide, water and one or more further components selected from the group consisting of organic solvents, further ionic compounds and additives; or where the electrolyte composition comprises an ionic compound selected from the group consisting of carboxylate compounds and carboxylic acids. Ionic compounds include ionic liquids and salts. Metal hydride batteries comprising certain electrolyte compositions have a nominal open-circuit voltage of from about 1.5 V to about 5.0 V.
FILED	Thursday, November 13, 2014
APPL NO	14/540537
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/24 (20130101) H01M 10/26 (20130101) Original (OR) Class H01M 10/28 (20130101) H01M 10/345 (20130101) H01M 2300/0014 (20130101) H01M 2300/0028 (20130101) H01M 2300/0037 (20130101)
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10243285 — Low resistance, low-inductance power connectors

US 10243285	Coteus et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Paul W. Coteus (Yorktown, New York); Andrew Ferencz (Southborough, Massachusetts); Shawn Anthony Hall (Pleasantville, New York); Todd Edward Takken (Brewster, New York)
ABSTRACT	An electrical connector includes an anode for conducting an electrical supply current from a source to a destination, a cathode for conducting an electrical return current from the destination to the source, and an insulator that prevents electrical conduction between the anode and the cathode. The first and second shapes are such as to provide a conformity of one to the other, with the insulator placed therebetween and having a predetermined relatively thin thickness. A predetermined low-resistance path for the supply current is provided respectively by the anode and the cathode, and a proximity of the anode to the cathode along these paths provides a predetermined low self-inductance of the connector. The anode and the cathode each comprises a plurality of sections that are disposed at one or more predetermined angles to form a rigid assembly that accommodates a geometry between the source and the destination.
FILED	Thursday, December 28, 2017
APPL NO	15/856295
ART UNIT	2831 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 1/26 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/70 (20130101) H01R 12/52 (20130101) Original (OR) Class H01R 12/62 (20130101) H01R 43/16 (20130101)
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10243385 — Secondary battery management system

US 10243385	MirTabatabaei et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Robert Bosch GmbH (Stuttgart, Germany)
ASSIGNEE(S)	Robert Bosch GmbH (Stuttgart, Germany)
INVENTOR(S)	Anahita MirTabatabaei (San Francisco, California); Reinhardt Klein (Mountain View, California); Aleksandar Kojic (Sunnyvale, California); Nalin Chaturvedi (Union City, California); Christopher Mayhew (Redondo Beach, California); John F. Christensen (Elk Grove, California)
ABSTRACT	A method of managing a battery system, the method including receiving at least one measured characteristic of the at least one battery cell from the at least one sensor, estimating at least one state of the at least one battery cell at a first time by applying an electrochemical-based battery model, estimating at least one physical parameter of the at least one battery cell based on the at least one measured characteristic and the estimation of the at least one state, estimating the at least one state at a second time, subsequent to the first time, by applying the electrochemical-based battery model based on the estimated at least one parameter, and regulating at least one of charging or discharging of the at least one battery cell based on the estimation of the at least one state.
FILED	Friday, January 29, 2016
APPL NO	15/011118
ART UNIT	2859 — Printing/Measuring and Testing
CURRENT CPC	Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 3/12 (20130101) B60L 11/1861 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3624 (20130101) G01R 31/3651 (20130101) G01R 31/3679 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/48 (20130101) H01M 10/425 (20130101) H01M 10/482 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/007 (20130101) Original (OR) Class
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10243660 — Ultrafast all-optical modulation of the visible and infrared spectrum with nanorod arrays

US 10243660	Chang et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois); UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S)	Northwester University (Evanston, Illinois); UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Robert P. H. Chang (Glenview, Illinois); Richard D. Schaller (Clarendon Hills, Illinois); John B. Ketterson (Evanston, Illinois); Peijun Guo (Evanston, Illinois)
ABSTRACT	Disclosed herein is a method of optical modulation, the method comprising irradiating an optical switch with a control beam at a first control time and irradiating the optical switch with a signal beam at a signal time. The transmitted intensity of the signal beam in a direction depends on the delay time between the first control time and the signal time and the transmitted intensity of the signal beam in the direction is detectably different than a static signal. The optical switch comprises a nanorod array, the nanorod array comprising a plurality of nanorods extending outwardly from a substrate.
FILED	Friday, February 03, 2017
APPL NO	15/424029
ART UNIT	2633 — Digital Communications
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Transmission H04B 10/11 (20130101) H04B 10/50 (20130101) Original (OR) Class
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10243984 — Path scanning for the detection of anomalous subgraphs and use of DNS requests and host agents for anomaly/change detection and network situational awareness

US 10243984	Neil et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Joshua Charles Neil (Jemez Springs, New Mexico); Michael Edward Fisk (Los Alamos, New Mexico); Alexander William Brugh (Los Alamos, New Mexico); Curtis Lee Hash, Jr. (Santa Fe, New Mexico); Curtis Byron Storlie (Jemez Springs, New Mexico); Benjamin Uphoff (Los Alamos, New Mexico); Alexander Kent (Los Alamos, New Mexico)
ABSTRACT	A system, apparatus, computer-readable medium, and computer-implemented method are provided for detecting anomalous behavior in a network. Historical parameters of the network are determined in order to determine normal activity levels. A plurality of paths in the network are enumerated as part of a graph representing the network, where each computing system in the network may be a node in the graph and the sequence of connections between two computing systems may be a directed edge in the graph. A statistical model is applied to the plurality of paths in the graph on a sliding window basis to detect anomalous behavior. Data collected by a Unified Host Collection Agent (“UHCA”) may also be used to detect anomalous behavior.
FILED	Friday, November 10, 2017
APPL NO	15/809297
ART UNIT	2433 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/577 (20130101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 7/005 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/002 (20130101) H04L 63/1408 (20130101) H04L 63/1416 (20130101) H04L 63/1425 (20130101) Original (OR) Class H04L 63/1433 (20130101) H04L 2463/144 (20130101)
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10244654 — Cold plate with combined inclined impingement and ribbed channels

US 10244654	Parida
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Pritish R. Parida (Fishkill, New York)
ABSTRACT	Methods for making heat transfer devices include forming a jet plate with a plurality of inclined jets set at an angular deviation from normal. A bottom plate is formed with channel walls that have ribs. The jet plate is attached to the bottom plate to form ribbed channels. The angular deviation of each inclined jet establishes a jet direction perpendicular to a long dimension of the ribbed channels.
FILED	Thursday, January 11, 2018
APPL NO	15/868433
ART UNIT	3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/26 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/02 (20130101) F28F 3/048 (20130101) F28F 13/02 (20130101) F28F 2215/10 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/467 (20130101) H01L 23/4735 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20218 (20130101) H05K 7/20254 (20130101) Original (OR) Class H05K 7/20263 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4935 (20150115) Y10T 29/49359 (20150115)
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10244665 — Effectiveness-weighted control of cooling system components

US 10244665	Campbell et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Levi A. Campbell (Poughkeepsie, New York); Richard C. Chu (Hopewell Junction, New York); Milnes P. David (Fishkill, New York); Michael J. Ellsworth, Jr. (Poughkeepsie, New York); Madhusudan K. Iyengar (Foster City, California); Roger R. Schmidt (Poughkeepsie, New York); Robert E. Simons (Poughkeepsie, New York)
ABSTRACT	Energy efficient control of cooling system cooling of an electronic system is provided based, in part, on weighted cooling effectiveness of the components. The control includes automatically determining speed control settings for multiple adjustable cooling components of the cooling system. The automatically determining is based, at least in part, on weighted cooling effectiveness of the components of the cooling system, and the determining operates to limit power consumption of at least the cooling system, while ensuring that a target temperature associated with at least one of the cooling system or the electronic system is within a desired range by provisioning, based on the weighted cooling effectiveness, a desired target temperature change among the multiple adjustable cooling components of the cooling system. The provisioning includes provisioning applied power to the multiple adjustable cooling components via, at least in part, the determined control settings.
FILED	Monday, December 07, 2015
APPL NO	14/960862
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 23/1932 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/2079 (20130101) H05K 7/20836 (20130101) Original (OR) Class
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National Science Foundation (NSF)

10238457 — System and method for endoscopic deployment of robotic concentric tube manipulators for performing surgery

US 10238457	Herrell et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	S. Duke Herrell (Nashville, Tennessee); Robert J. Webster, III (Nashville, Tennessee); Trevor Bruns (Nashville, Tennessee); Philip J. Swaney (Nashville, Tennessee); Richard Hendrick (Nasvhville, Tennessee)
ABSTRACT	An apparatus (20) for performing endoscopic surgery on a patient (12) includes at least two concentric tube manipulators (150) adapted to carry devices (152, 154) for performing a surgical operation. A transmission (200) operates the concentric tube manipulators (150). An endoscope tube (106) has a proximal end portion fixed to the transmission (200). The concentric tube manipulators (150) extend from the transmission (200) through an inner lumen (102) of the endoscope tube (106) and are operable to extend from a distal end (104) of the endoscope tube.
FILED	Friday, April 18, 2014
APPL NO	14/256540
ART UNIT	3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/0016 (20130101) A61B 1/00087 (20130101) A61B 1/00131 (20130101) A61B 1/00133 (20130101) A61B 1/303 (20130101) A61B 1/307 (20130101) A61B 18/22 (20130101) A61B 34/30 (20160201) Original (OR) Class A61B 34/70 (20160201) A61B 34/72 (20160201) A61B 34/74 (20160201) A61B 90/30 (20160201) A61B 90/361 (20160201) A61B 2034/301 (20160201) A61B 2034/742 (20160201)
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10239012 — Methods of separating molecules

US 10239012	First et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Defense Science and Engineering Graduate Fellowship (NDSEG) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET) Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
ASSIGNEE(S)	The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S)	Eric L. First (Princeton, New Jersey); M. M. Faruque Hasan (Princeton, New Jersey); Christodoulos A. Floudas (Princeton, New Jersey)
ABSTRACT	Disclosed herein are new methods, machines, processes, and systems for separating molecules by determining better materials and process optimization conditions. As a result of these advances, this disclosure provides improved carbon dioxide capture, better flue gas treatments, and more efficient methods of purifying gases have been developed. Optimal sorbents can be obtained by using a computational screening method that selects microporous structures (e.g. zeolites and metal-organic frameworks) from a database of materials with the greatest potential for cost-effective separations. The disclosed methods are the first to consider both the size and shape of the adsorbent material. This is also the first disclosure to consider the process application and cost when selecting which material to use.
FILED	Wednesday, February 05, 2014
APPL NO	14/766388
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/04 (20130101) Original (OR) Class B01D 53/26 (20130101) B01D 53/047 (20130101) B01D 2253/108 (20130101) B01D 2253/116 (20130101) B01D 2253/204 (20130101) B01D 2256/245 (20130101) B01D 2257/80 (20130101) B01D 2257/102 (20130101) B01D 2257/504 (20130101) B01D 2257/7025 (20130101) Electric Digital Data Processing G06F 17/50 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/08 (20130101) Y02C 20/20 (20130101)
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10239022 — Porous calcium-silicates and method of synthesis

US 10239022	Shahsavari et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	C-Crete Technologies LLC (Stafford, Texas)
ASSIGNEE(S)	C-Crete Technologies, LLC (Stafford, Texas)
INVENTOR(S)	Rouzbeh Shahsavari (Houston, Texas); Vahid Hejazi (Houston, Texas)
ABSTRACT	Mesoporous membranes have shown promising separation performance with a potential to lower the energy consumption, leading to a dramatic cost reduction. Recently, an extensive effort has been made on the design of membranes which brought a significant progress toward the synthesis of well-defined porous morphologies, most of which synthesized by surfactant-template methodology. Currently, the most well-designed state-of-the-art membranes using this technique are made from metals, polymers, carbon, silica, etc. In the present invention, we demonstrate mesoporous calcium-silicate particles having superior separation capacity and optimal permeability, thereby leading to reduced energy consumption for selective separation of gases/liquids and/or the combination thereof. We explore various methods to improve the calcium-silicate membranes properties by tuning pore density during the synthesis/aging process, while favoring the formation of uniformly distributed nanopores. Lowering particle density by controlling calcium to silicon ratio along with optimizing the surface area are essential in achieving our objective.
FILED	Monday, May 02, 2016
APPL NO	15/144811
ART UNIT	1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/228 (20130101) B01D 67/0041 (20130101) B01D 67/0046 (20130101) B01D 67/0048 (20130101) B01D 67/0069 (20130101) B01D 69/02 (20130101) B01D 69/10 (20130101) B01D 71/027 (20130101) Original (OR) Class B01D 2325/04 (20130101) B01D 2325/20 (20130101) B01D 2325/22 (20130101) B01D 2325/28 (20130101) B01D 2325/30 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/10 (20130101) B01J 20/28004 (20130101) B01J 20/28007 (20130101) B01J 20/28033 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 11/00 (20130101) F17C 11/007 (20130101)
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10239302 — Layer-by-layer assembly of graphene oxide membranes via electrostatic interaction and eludication of water and solute transport mechanisms

US 10239302	Mi et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	University of Maryland (College Park, Maryland)
ASSIGNEE(S)	University of Maryland, College Park (College Park, Maryland)
INVENTOR(S)	Baoxia Mi (Moraga, California); Meng Hu (Baltimore, Maryland)
ABSTRACT	A method for synthesizing a water purification membrane is presented. The method includes stacking a plurality of graphene oxide (GO) nanosheets to create the water purification membrane, the stacking involving layer-by-layer assembly of the plurality of GO nanosheets and forming a plurality of nanochannels between the plurality of GO nanosheets for allowing the flow of a fluid and for rejecting the flow of contaminants. The method further includes cross-linking the plurality of GO nanosheets by 1,3,5-benzenetricarbonyl trichloride on a polydopamine coated polysulfone support.
FILED	Monday, February 26, 2018
APPL NO	15/905219
ART UNIT	1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Separation B01D 61/002 (20130101) B01D 61/025 (20130101) B01D 65/08 (20130101) B01D 67/0006 (20130101) B01D 69/10 (20130101) B01D 69/12 (20130101) B01D 69/148 (20130101) B01D 71/021 (20130101) B01D 71/60 (20130101) B01D 71/68 (20130101) B01D 2323/30 (20130101) B01D 2325/14 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/14 (20130101) Original (OR) Class B32B 2038/0076 (20130101) B32B 2310/025 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/23 (20170801) C01B 32/198 (20170801) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115)
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10239788 — Self-healing composite of thermoset polymer and programmed super contraction fibers

US 10239788	Li et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Guoqiang Li (Baton Rouge, Louisiana); Harper Meng (Baton Rouge, Louisiana)
ASSIGNEE(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S)	Guoqiang Li (Baton Rouge, Louisiana); Harper Meng (Baton Rouge, Louisiana)
ABSTRACT	A composition comprising thermoset polymer, shape memory polymer to facilitate macro scale damage closure, and means for molecular scale healing has the ability to repair structural defects by a bio-mimetic, close-then-heal process. The shape memory polymer serves to bring surfaces of a structural defect into proximity, after which the healing means moves into the defect and provides molecular scale healing. The means for molecular scale healing can be a thermoplastic, such as fibers, particles or spheres, which are heated to or above the thermoplastic's melting point, and then the composition is cooled below that melting temperature. The compositions can not only close macroscopic defects, but they can also do so repeatedly even if damage recurs in a previously healed/repaired area.
FILED	Tuesday, July 19, 2016
APPL NO	15/213926
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 73/18 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 16/0675 (20130101) C04B 16/0675 (20130101) C04B 16/0675 (20130101) C04B 16/0675 (20130101) C04B 20/1037 (20130101) C04B 20/1037 (20130101) C04B 26/04 (20130101) C04B 26/04 (20130101) C04B 26/16 (20130101) Original (OR) Class C04B 26/26 (20130101) C04B 26/26 (20130101) C04B 28/02 (20130101) C04B 28/02 (20130101) C04B 40/0675 (20130101) C04B 40/0675 (20130101) C04B 40/0675 (20130101) C04B 2103/0065 (20130101) C04B 2103/0065 (20130101) C04B 2103/0065 (20130101) C04B 2103/0065 (20130101) C04B 2111/72 (20130101) C04B 2111/00612 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/664 (20130101) C08G 18/3206 (20130101) C08G 18/4238 (20130101) C08G 18/7671 (20130101) C08G 2101/0025 (20130101) C08G 2280/00 (20130101) C08G 2350/00 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/70 (20130101)
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10239824 — Automated synthesis of small molecules using chiral, non-racemic boronates

US 10239824	Burke et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Martin D. Burke (Champaign, Illinois); Junqi Li (Champaign, Illinois); Eric P. Gillis (Wallingford, Connecticut)
ABSTRACT	Provided are methods for making and using chiral, non-racemic protected organoboronic acids, including pinene-derived iminodiacetic acid (PIDA) boronates, to direct and enable stereoselective synthesis of organic molecules. Also provided are methods for purifying PIDA boronates from solution. Also provided are methods for deprotection of boronic acids from their PIDA ligands. The purification and deprotection methods may be used in conjunction with methods for coupling or otherwise reacting boronic acids. Iterative cycles of deprotection, coupling, and purification can be performed to synthesize chiral, non-racemic compounds. The methods are suitable for use in an automated chemical synthesis process. Also provided is an automated small molecule synthesizer apparatus for performing automated stereoselective synthesis of chiral, non-racemic small molecules using iterative cycles of deprotection, coupling, and purification.
FILED	Monday, July 11, 2016
APPL NO	15/207196
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 227/32 (20130101) C07C 227/32 (20130101) C07C 229/14 (20130101) Original (OR) Class C07C 229/16 (20130101) C07C 229/24 (20130101) C07C 2601/08 (20170501) C07C 2601/14 (20170501) C07C 2602/42 (20170501) Heterocyclic Compounds C07D 207/16 (20130101) C07D 207/44 (20130101) C07D 211/60 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101)
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10239878 — Macrocyclic ligands with pendant chelating moieties and complexes thereof

US 10239878	Tatum et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA)
APPLICANT(S)	LUMIPHORE, INC. (Berkeley, California)
ASSIGNEE(S)	LUMIPHORE, INC. (Berkeley, California)
INVENTOR(S)	David Tatum (Berkeley, California); Jide Xu (Richmond, California); Darren Magda (San Leandro, California); Nathaniel Butlin (Pacifica, California)
ABSTRACT	The invention relates to ligands and complexes of metal ions with the ligands useful in various applications, including therapeutic and diagnostic applications.
FILED	Wednesday, March 07, 2018
APPL NO	15/914945
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 51/0482 (20130101) Heterocyclic Compounds C07D 471/18 (20130101) Original (OR) Class C07D 491/22 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/182 (20130101) C09K 2211/1029 (20130101)
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10240090 — Fire retardant materials and devices including same

US 10240090	Bhowmik et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR) Small Business Technology Transfer (STTR)
APPLICANT(S)	THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION on behalf of THE UNIVERSITY OF NEVADA, LAS VEGAS (Las Vegas, Nevada); INNOSENSE LLC (Torrance, California)
ASSIGNEE(S)	THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (Las Vegas, Nevada); INNOSENSE LLC (Torrance, California)
INVENTOR(S)	Pradip K. Bhowmik (Henderson, Nevada); Kisholoy Goswami (Redondo Beach, California); Maksudul M. Alam (Glendora, California); Haesook Han (Henderson, Nevada)
ABSTRACT	This disclosure provides fire retardant materials, including polymers that include at least one pyridinium salt moiety and at least one phosphine oxide moiety. In some cases, fire retardant polymers provided herein have the following structure:
FILED	Friday, August 28, 2015
APPL NO	15/507723
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 79/04 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 21/14 (20130101) Original (OR) Class
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10240158 — Compositions and methods for making selenocysteine containing polypeptides

US 10240158	Soll et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF)
APPLICANT(S)	Yale University (New Haven, Connecticut)
ASSIGNEE(S)	Yale University (New Haven, Connecticut)
INVENTOR(S)	Dieter Soll (Guilford, Connecticut); Caroline Aldag (New Haven, Connecticut); Michael Hohn (Scotch Plains, New Jersey); Corwin Miller (New Haven, Connecticut)
ABSTRACT	Non-naturally occurring tRNA^Secand methods of using them for recombinant expression of proteins engineered to include one or more selenocysteine residues are disclosed. The non-naturally occurring tRNA^Seccan be used for recombinant manufacture of selenocysteine containing polypeptides encoded by mRNA without the requirement of an SECIS element. In some embodiments, selenocysteine containing polypeptides are manufactured by co-expressing a non-naturally occurring tRNA^Seca recombinant expression system, such as E. coli, with SerRS, EF-Tu, SelA, or PSTK and SepSecS, and an mRNA with at least one codon that recognizes the anticodon of the non-naturally occurring tRNA^Sec.
FILED	Tuesday, July 05, 2016
APPL NO	15/202194
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/67 (20130101) C12N 15/70 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101)
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10240163 — Increasing the content of long chain fatty acids in seed oil

US 10240163	Wang et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Basic Energy Sciences (BES) Energy Frontier Research Centers (EFRC) Center for Advanced Biofuel Systems (CABS) Materials Sciences and Engineering Division (MSE) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI) Division of Molecular and Cellular Biosciences (MCB) U.S. State Government State of Kansas Kansas Lipidomics Research Center (KLRC)
APPLICANT(S)	Donald Danforth Plant Science Center (St. Louis, Missouri); The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S)	Donald Danforth Plant Science Center (St. Louis, Missouri); The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S)	Xuemin Wang (St. Louis, Missouri); Maoyin Li (St. Louis, Missouri)
ABSTRACT	Provided are plants that express, or overexpress, a pPLAIIIδ protein. Constitutive or seed-specific expression of pPLAIIIδ protein in Arabidopsis increases seed oil content, the amount of C20 and C22 fatty acids, and the amount of C56, C58, and C60 triacylglycerols, effectively resulting in significantly higher oil yield per plant. Use of pPLAIIIδ is therefore an effective biotechnological tool to significantly increase plant yield, including oil, and the amount of high value long chain fatty acids in agricultural and horticultural crops, especially oilseed crops.
FILED	Friday, September 25, 2015
APPL NO	14/866125
ART UNIT	1662 — Plants
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 69/604 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/20 (20130101) C12N 15/8247 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6463 (20130101) Enzymes C12Y 301/01 (20130101)
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10240174 — Benzylisoquinoline alkaloid (BIA) precursor producing microbes, and methods of making and using the same

US 10240174	Siddiqui et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Michael Shareef Siddiqui (San Mateo, California); Christina D. Smolke (Menlo Park, California)
ABSTRACT	Host cells that are engineered to produce benzylisoquinoline alkaloid (BIAs) precursors, such as norcoclaurine (NC) and norlaudanosoline (NL), are provided. The host cells may have one or more engineered modifications selected from: a feedback inhibition alleviating mutation in a enzyme gene; a transcriptional modulation modification of a biosynthetic enzyme gene; an inactivating mutation in an enzyme; and a heterologous coding sequence. Also provided are methods of producing a BIA of interest or a precursor thereof using the host cells and compositions, e.g., kits, systems etc., that find use in methods of the invention.
FILED	Monday, November 03, 2014
APPL NO	15/031618
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0071 (20130101) C12N 9/90 (20130101) C12N 9/1085 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/24 (20130101) C12P 13/001 (20130101) C12P 13/225 (20130101) C12P 17/12 (20130101) Original (OR) Class
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10240242 — Bromide removal from aqueous solutions

US 10240242	Scherson
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Daniel A. Scherson (Cleveland, Ohio)
ABSTRACT	Systems and processes for removing and purifying bromide from an aqueous bromide solution are described. Electrochemistry is used to either convert bromide to bromine to allow its extraction in an organic phase, or to cause deposition of bromine onto an electrode. In either case, once removed from the aqueous bromide solution, the bromide can be recovered and purified.
FILED	Friday, September 11, 2015
APPL NO	15/510926
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Separation B01D 11/0419 (20130101) B01D 11/0492 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/26 (20130101) C02F 1/469 (20130101) C02F 1/46109 (20130101) C02F 2001/46123 (20130101) C02F 2001/46133 (20130101) C02F 2001/46161 (20130101) C02F 2101/12 (20130101) C02F 2201/4618 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/24 (20130101) Original (OR) Class C25B 9/00 (20130101) C25B 9/06 (20130101) C25B 11/035 (20130101)
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10240910 — Systems and methods for compressive image sensor techniques utilizing sparse measurement matrices

US 10240910	Leitner et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	Stefan Leitner (Carbondale, Illinois); Haibo Wang (Carbondale, Illinois); Spyros Tragoudas (Carbondale, Illinois)
ASSIGNEE(S)	Board of Trustees of Southern Illinois University on Behalf of Southern Illinois University Carbondale (Carbondale, Illinois)
INVENTOR(S)	Stefan Leitner (Carbondale, Illinois); Haibo Wang (Carbondale, Illinois); Spyros Tragoudas (Carbondale, Illinois)
ABSTRACT	Systems and methods for compressive image sensor techniques based on sparse measurement matrices are disclosed. A method to perform compressive sensing (CS) measurement operations for image sensors limits pixel summation to be within neighboring pixels and hence dramatically simplifies CS image sensor circuits and reduces their power consumption while providing better image quality compared to conventional random measurement matrix based methods. A sparse measurement matrix is applied to pixel data to generate a desired number of summation groups, each summation group consisting of outputs from an equal number of pixel cells. Each pair of summation groups contains the same number of shared outputs from pixel cells. From the summation groups, an image captured by the pixel cells is recovered.
FILED	Thursday, September 07, 2017
APPL NO	15/698236
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/02 (20130101) Original (OR) Class Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 35/08 (20130101) Pictorial Communication, e.g Television H04N 5/232 (20130101) H04N 5/335 (20130101) H04N 5/341 (20130101) H04N 5/347 (20130101)
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10241015 — Cryogenic cooling positioning apparatus, methods and applications

US 10241015	Hollabaugh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Mitegen, LLC (Ithaca, New York)
ASSIGNEE(S)	Mitegen, LLC (Ithaca, New York)
INVENTOR(S)	Stephen Hollabaugh (Ithaca, New York); Robert Newman (Groton, New York); David Closs (Freeville, New York)
ABSTRACT	A method and a cryogenic sample positioning system are provided which include: a sample holder cassette that is vertically coupled to a carousel gear through a first shaft. Each sample holder cassette has a first degree of rotation about the first shaft. A first planet drive gear underlies and is vertically coupled to the carousel gear through a second shaft that extends from the carousel gear through the first planet drive gear. The carousel gear has a second degree of rotation about the second shaft that is different from the first degree of rotation. A planet gear that is laterally connected to a second planet drive gear is interposed between each of the carousel gear and the first planet drive gear. Each of the planet gear and the second planet drive gear selectively define the first degree of rotation, without affecting the second degree of rotation of the carousel gear.
FILED	Monday, July 24, 2017
APPL NO	15/657988
ART UNIT	3655 — Material and Article Handling
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0242 (20130101) A01N 1/0257 (20130101) A01N 1/0268 (20130101) Gearing F16H 1/28 (20130101) F16H 57/08 (20130101) F16H 57/12 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 19/005 (20130101) Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 3/11 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/42 (20130101) Original (OR) Class G01N 23/20033 (20130101) G01N 35/025 (20130101) G01N 2035/0486 (20130101) G01N 2223/604 (20130101)
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10241028 — Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures

US 10241028	Rowe et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) National Science Foundation (NSF)
APPLICANT(S)	Steven M. Rowe (Birmingham, Alabama); Guillermo J. Tearney (Cambridge, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts); Linbo Liu (Cambridge, Massachusetts); Eric J. Sorscher (Birmingham, Alabama); Kengyeh Ken Chu (Jamaica Plain, Massachusetts); Bradford James Diephuis (Brookline, Massachusetts); Eric James Wilsterman (Boston, Massachusetts); Gregory Andrew Dierksen (Brookline, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Steven M. Rowe (Birmingham, Alabama); Guillermo J. Tearney (Cambridge, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts); Linbo Liu (Cambridge, Massachusetts); Eric J. Sorscher (Birmingham, Alabama); Kengyeh Ken Chu (Jamaica Plain, Massachusetts); Bradford James Diephuis (Brookline, Massachusetts); Eric James Wilsterman (Boston, Massachusetts); Gregory Andrew Dierksen (Brookline, Massachusetts)
ABSTRACT	Exemplary apparatus and method can be provided for obtaining data regarding a plurality of samples. For example, using at least one arrangement, it is possible to receive interferometric information that is based on radiations provided from a reference and the samples that are provided in respective chambers. Alternatively and/or in addition, based on the interferometric information, it is possible to discriminate between agents to identify a particular agent that affects a particular function within at least one of the samples.
FILED	Monday, August 27, 2012
APPL NO	14/240938
ART UNIT	2886 — Optics
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0205 (20130101) G01B 9/02044 (20130101) G01B 9/02091 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/45 (20130101) G01J 9/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/14 (20130101) G01N 15/0205 (20130101) G01N 21/17 (20130101) Original (OR) Class G01N 21/35 (20130101) G01N 21/45 (20130101) G01N 21/4788 (20130101) G01N 21/4795 (20130101) G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 29/00 (20130101) G01N 2021/653 (20130101) G01N 2021/655 (20130101)
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10241041 — Biological tissue analysis by inverse spectroscopic optical coherence tomography

US 10241041	Backman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Vadim Backman (Chicago, Illinois); Ji Yi (Evanston, Illinois)
ABSTRACT	A method and system to measure and image the full optical scattering properties by inverse spectroscopic optical coherence tomography (ISOCT) is disclosed. Tissue is modeled as a medium with continuous refractive index (RI) fluctuation and such a fluctuation is described by the RI correlation functions. By measuring optical quantities of tissue (including the scattering power of the OCT spectrum, the reflection albedo α defined as the ratio or scattering coefficient μ_s, and the back-scattering coefficient μ_b), the RI correlation function can be inversely deduced and the full set of optical scattering properties can be obtained.
FILED	Tuesday, May 09, 2017
APPL NO	15/590745
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0066 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4795 (20130101) Original (OR) Class
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10241110 — Plasmonic biosensors with built-in artificial antibodies

US 10241110	Singamaneni et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Washington University in St. Louis (St. Louis, Missouri)
ASSIGNEE(S)	Washington University in St. Louis (St. Louis, Missouri)
INVENTOR(S)	Srikanth Singamaneni (St. Louis, Missouri); Limei Tian (St. Louis, Missouri); Keng-Ku Liu (Philadelphia, Pennsylvania); Abdennour Abbas (St. Louis, Missouri); Jeremiah J. Morrissey (St. Louis, Missouri); Evan D. Kharasch (St. Louis, Missouri)
ABSTRACT	Plasmonic nanotransducers, methods of preparing plasmonic nanotransducers, and methods for label-free detection of target molecules are disclosed. The plasmonic nanotransducers include hollow nanostructure cores and artificial antibodies. The plasmonic nanotransducers are exposed to a biological sample that can contain the specific target molecules. The plasmonic nanotransducers can be analyzed with surface enhanced Raman scattering techniques and/or localized surface plasmon resonance techniques to quantify the amount of the target molecule in the sample.
FILED	Friday, October 17, 2014
APPL NO	15/030004
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) G01N 33/553 (20130101) G01N 33/54346 (20130101) G01N 33/54373 (20130101) Original (OR) Class
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10241173 — Systems and methods for designing magnetic resonance fingerprinting imaging parameters

US 10241173	Zhao et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts); The University of Southern California (Los Angeles, California)
INVENTOR(S)	Bo Zhao (Malden, Massachusetts); Justin P. Haldar (Los Angeles, California); Lawrence Wald (Cambridge, Massachusetts)
ABSTRACT	Systems and methods for acquiring magnetic resonance fingerprinting (MRF) imaging data from a subject using a magnetic resonance imaging (MRI) system are provided. The method includes receiving an indication of an MRF imaging process to be performed by the MRI system and receiving a desired design objective for the MRF imaging process and a configuration metric associated with the MRF imaging process. The method further includes using the configuration metric to bound a variance of tissue parameter estimates associated with the MRF imaging process and determine imaging parameters that achieve the desired design objective. The method also includes performing the MRF imaging process using the determined imaging parameters to acquire MRF data using the MRI system.
FILED	Monday, March 06, 2017
APPL NO	15/450127
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) Original (OR) Class G01R 33/5608 (20130101)
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10241199 — Ultrasonic/photoacoustic imaging devices and methods

US 10241199	Witte et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF)
APPLICANT(S)	The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S)	The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S)	Russell S. Witte (Tucson, Arizona); Leonardo Gabriel Montilla (Tucson, Arizona); Ragnar Olafsson (Tucson, Arizona); Charles M. Ingram (Tucson, Arizona); Zhaohui Wang (Tucson, Arizona); Robert A. Norwood (Tucson, Arizona); Charles Greenlee (Tucson, Arizona)
ABSTRACT	Devices are disclosed for obtaining data of a sample, particularly data capable of being processed to produce an image of a region of the sample. An exemplary device includes a light-beam source, an acoustic-wave source, an optical element, and an acoustic detector. The optical element is transmissive to a light beam produced by the light-beam source and reflective to acoustic waves produced by the acoustic-wave source. The optical element is situated to direct the transmitted light beam and reflected acoustic wave simultaneously along an optical axis to be incident at a situs in or on a sample to cause the sample to produce acoustic echoes from the incident acoustic waves while also producing photoacoustic waves from the incident light beam photoacoustically interacting with the situs. The acoustic detector is placed to receive and detect the acoustic echoes and the photoacoustic waves from the situs. The acoustic detector can comprise one or more hydrophones exploiting the acousto-electric effect.
FILED	Tuesday, November 04, 2014
APPL NO	14/533013
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0093 (20130101) A61B 5/0095 (20130101) A61B 5/7257 (20130101) A61B 8/08 (20130101) A61B 8/0825 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) G01N 29/0672 (20130101) G01N 29/2418 (20130101) G01N 2291/02475 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52 (20130101) G01S 7/52017 (20130101) Original (OR) Class G01S 15/02 (20130101)
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10241233 — Methods and apparatus for monitoring interactions between particles and molecules using nanophotonic trapping

US 10241233	Erickson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S)	CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S)	David Erickson (Ithaca, New York); Pilgyu Kang (Ithaca, New York)
ABSTRACT	A method for characterizing an interaction between a first particle and a second particle is provided. The method includes the steps of: (i) providing an optical trap system including a photonics-based trap, a light source, and a camera; (ii) optically trapping, using the photonics-based trap, the first particle; (iii) obtaining a first measurement of a trap stiffness of the photonics-based trap; (iv) introducing the second particle to the optically trapped particle; (v) incubating the first and second particles under conditions suitable for an interaction between the first and second particles; (vi) obtaining a second measurement of the trap stiffness of the photonics-based trap after the incubation; and (vii) determining, using the first measurement of trap stiffness and the second measurement of trap stiffness, a property of the interaction between the first particle and the second particle.
FILED	Wednesday, August 12, 2015
APPL NO	14/824423
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/25 (20130101) G01N 21/47 (20130101) G01N 33/542 (20130101) Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) Original (OR) Class G02B 21/32 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101)
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10242427 — Deviation magnification: revealing departures from ideal geometries

US 10242427	Wadhwa et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Neal Wadhwa (Cambridge, Massachusetts); Tali Dekel (Cambridge, Massachusetts); Donglai Wei (Arlington, Massachusetts); Frederic Pierre Durand (Somerville, Massachusetts); William T. Freeman (Acton, Massachusetts)
ABSTRACT	Geometries of the structures and objects deviate from their idealized models, while not always visible to the naked eye. Embodiments of the present invention reveal and visualize such subtle geometric deviations, which can contain useful, surprising information. In an embodiment of the present invention, a method can include fitting a model of a geometry to an input image, matting a region of the input image according to the model based on a sampling function, generating a deviation function based on the matted region, extrapolating the deviation function to an image wide warping field, and generating an output image by warping the input image according to the warping. In an embodiment of the present invention, Deviation Magnification inputs takes a still image or frame, fits parametric models to objects of interest, and generates an output image exaggerating departures from ideal geometries.
FILED	Friday, July 29, 2016
APPL NO	15/223438
ART UNIT	2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image Data Processing or Generation, in General G06T 3/0093 (20130101) Original (OR) Class G06T 11/00 (20130101) G06T 11/001 (20130101)
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10243446 — Current reference based selective harmonic current mitigation pulsed width modulation

US 10243446	Wang et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S)	Shuo Wang (Gainesville, Florida); Amirhossein Moeini (Gainesville, Florida); Hui Zhao (Gainesville, Florida)
ABSTRACT	Methods and apparatuses for selective harmonic current mitigation pulse width modulation (SHCM-PWM) are provided. Low switching frequencies can be utilized for grid connected cascaded H-bridge multilevel rectifiers to meet harmonic requirements within an extended harmonic spectrum. Instead of using voltage references to calculate switching angles for rectifiers as in conventional selective harmonic elimination-PWM (SHE-PWM) and selective harmonic mitigation-PWM (SHM-PWM), current references can be used to compensate for current harmonics and meet current harmonic requirements and total demand distortion (TDD) within the entire harmonic spectrum.
FILED	Friday, February 02, 2018
APPL NO	15/887620
ART UNIT	2838 — Electrical Circuits and Systems
CURRENT CPC	Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/01 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/08 (20130101) H02M 1/12 (20130101) H02M 1/126 (20130101) Original (OR) Class H02M 7/49 (20130101) H02M 7/487 (20130101) H02M 7/5395 (20130101) H02M 2007/4835 (20130101)
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10243485 — Peg-style electrostatic rotating machine employing dielectric sleeves

US 10243485	Ge et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Baoyun Ge (Madison, Wisconsin); Daniel Colin Ludois (Madison, Wisconsin)
ABSTRACT	An electrostatic rotating electrical machine employs axially extending electrically conductive pegs (for example, on a stator) interacting with the least one of a comparable set of overlapping axially extending pegs on a rotor or a dielectric sleeve which experiences an induced electrostatic charge electrostatically attracted to the stator pegs. A dielectric sleeve may also encase either one or both of the rotor pegs and stator pegs to provide improved electrostatic field shaping and reduced dielectric fluid usage and mechanical susceptibility.
FILED	Monday, May 18, 2015
APPL NO	14/715214
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Electric Machines Not Otherwise Provided for H02N 1/00 (20130101) H02N 1/00 (20130101) H02N 1/002 (20130101) H02N 1/002 (20130101) H02N 1/08 (20130101) Original (OR) Class
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10243660 — Ultrafast all-optical modulation of the visible and infrared spectrum with nanorod arrays

US 10243660	Chang et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois); UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S)	Northwester University (Evanston, Illinois); UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Robert P. H. Chang (Glenview, Illinois); Richard D. Schaller (Clarendon Hills, Illinois); John B. Ketterson (Evanston, Illinois); Peijun Guo (Evanston, Illinois)
ABSTRACT	Disclosed herein is a method of optical modulation, the method comprising irradiating an optical switch with a control beam at a first control time and irradiating the optical switch with a signal beam at a signal time. The transmitted intensity of the signal beam in a direction depends on the delay time between the first control time and the signal time and the transmitted intensity of the signal beam in the direction is detectably different than a static signal. The optical switch comprises a nanorod array, the nanorod array comprising a plurality of nanorods extending outwardly from a substrate.
FILED	Friday, February 03, 2017
APPL NO	15/424029
ART UNIT	2633 — Digital Communications
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Transmission H04B 10/11 (20130101) H04B 10/50 (20130101) Original (OR) Class
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10243696 — Diversity combining of non-coherently modulated LDPC codes in wireless communications

US 10243696	Borle et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	Kapil Borle (Watertown, Massachusetts); Biao Chen (Jamesville, New York); Fangfang Zhu (Bridgewater, New Jersey); Yu Zhao (Somerville, Massachusetts)
ASSIGNEE(S)	Syracuse University (Syracuse, New York)
INVENTOR(S)	Kapil Borle (Watertown, Massachusetts); Biao Chen (Jamesville, New York); Fangfang Zhu (Bridgewater, New Jersey); Yu Zhao (Somerville, Massachusetts)
ABSTRACT	A method of decoding a plurality of diverse signals for low-density parity-check (LDPC) decoders that takes advantage of signal diversity. The method allows for the combining of soft-decision LDPC encoded non-coherently modulated signals, which is in contrast to existing approaches where hard decision combining is used for non-coherently modulated signals. The method includes the steps of inputting each diversity signal into a unique demodulator, and calculating the LLR of each demodulated signal. When the diverse demodulated signals are combined into a single combined signal, each bit of the combined signal is selected according to the value of either the highest LLR value of each bit across the demodulated signals or according to the sum of the LLR of each bit across the demodulated signals.
FILED	Tuesday, November 24, 2015
APPL NO	14/950191
ART UNIT	2631 — Digital Communications
CURRENT CPC	Transmission H04B 7/08 (20130101) H04B 7/0885 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0045 (20130101) H04L 1/0054 (20130101) Original (OR) Class H04L 1/0057 (20130101)
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10244628 — Printed electronics

US 10244628	Crain et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil and Mechanical Systems (CMS)
APPLICANT(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey); VORBECK MATERIALS CORPORATION (Jessup, Maryland)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey); VORBECK MATERIALS CORPORATION (Jessup, Maryland)
INVENTOR(S)	John M. Crain (Washington, District of Columbia); John S. Lettow (Washington, District of Columbia); Ilhan A. Aksay (Princeton, New Jersey); Sibel Korkut (Princeton, New Jersey); Katherine S. Chiang (Princeton, New Jersey); Chuan-Hua Chen (Princeton, New Jersey); Robert K. Prud'homme (Princeton, New Jersey)
ABSTRACT	Printed electronic device comprising a substrate onto at least one surface of which has been applied a layer of an electrically conductive ink comprising functionalized graphene sheets and at least one binder. A method of preparing printed electronic devices is further disclosed.
FILED	Monday, March 05, 2018
APPL NO	15/911623
ART UNIT	2816 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/02 (20130101) C01P 2006/12 (20130101) C01P 2006/40 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/46 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/65 (20180101) C09D 7/70 (20180101) C09D 11/037 (20130101) C09D 11/52 (20130101) C09D 11/102 (20130101) C09D 171/02 (20130101) C09D 177/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/092 (20130101) H05K 1/095 (20130101) Original (OR) Class H05K 3/12 (20130101) H05K 3/0091 (20130101) H05K 2201/0323 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/734 (20130101) Y10S 977/847 (20130101) Y10S 977/932 (20130101)
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National Aeronautics and Space Administration (NASA)

10239788 — Self-healing composite of thermoset polymer and programmed super contraction fibers

US 10239788	Li et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Guoqiang Li (Baton Rouge, Louisiana); Harper Meng (Baton Rouge, Louisiana)
ASSIGNEE(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S)	Guoqiang Li (Baton Rouge, Louisiana); Harper Meng (Baton Rouge, Louisiana)
ABSTRACT	A composition comprising thermoset polymer, shape memory polymer to facilitate macro scale damage closure, and means for molecular scale healing has the ability to repair structural defects by a bio-mimetic, close-then-heal process. The shape memory polymer serves to bring surfaces of a structural defect into proximity, after which the healing means moves into the defect and provides molecular scale healing. The means for molecular scale healing can be a thermoplastic, such as fibers, particles or spheres, which are heated to or above the thermoplastic's melting point, and then the composition is cooled below that melting temperature. The compositions can not only close macroscopic defects, but they can also do so repeatedly even if damage recurs in a previously healed/repaired area.
FILED	Tuesday, July 19, 2016
APPL NO	15/213926
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 73/18 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 16/0675 (20130101) C04B 16/0675 (20130101) C04B 16/0675 (20130101) C04B 16/0675 (20130101) C04B 20/1037 (20130101) C04B 20/1037 (20130101) C04B 26/04 (20130101) C04B 26/04 (20130101) C04B 26/16 (20130101) Original (OR) Class C04B 26/26 (20130101) C04B 26/26 (20130101) C04B 28/02 (20130101) C04B 28/02 (20130101) C04B 40/0675 (20130101) C04B 40/0675 (20130101) C04B 40/0675 (20130101) C04B 2103/0065 (20130101) C04B 2103/0065 (20130101) C04B 2103/0065 (20130101) C04B 2103/0065 (20130101) C04B 2111/72 (20130101) C04B 2111/00612 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/664 (20130101) C08G 18/3206 (20130101) C08G 18/4238 (20130101) C08G 18/7671 (20130101) C08G 2101/0025 (20130101) C08G 2280/00 (20130101) C08G 2350/00 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/70 (20130101)
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10240000 — Aromatic polyimides suitable for 3D printing processes

US 10240000	Avakian et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	POLYONE CORPORATION (Avon Lake, Ohio); THE UNITED STATES OF AMERICA as represented by THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (Washington, District of Columbia)
ASSIGNEE(S)	PolyOne Corporation (Avon Lake, Ohio); The Unted States of America as represented by The Administrator of the National Aeronautics and Space Administrations (Washington, District of Columbia)
INVENTOR(S)	Roger W. Avakian (Solon, Ohio); Ling Hu (Westlake, Ohio); Chun-Hua Chuang (Brecksville, Ohio)
ABSTRACT	Novel aromatic polyimides are disclosed with sufficient physical properties to be useful in 3D printing.
FILED	Wednesday, September 24, 2014
APPL NO	15/024838
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0004 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/105 (20130101) C08G 73/1014 (20130101) C08G 73/1028 (20130101) C08G 73/1067 (20130101) Original (OR) Class C08G 73/1071 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/24 (20130101) C08J 5/042 (20130101) C08J 2379/08 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/06 (20130101) C08K 7/06 (20130101) Compositions of Macromolecular Compounds C08L 79/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 179/08 (20130101)
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10240090 — Fire retardant materials and devices including same

US 10240090	Bhowmik et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR) Small Business Technology Transfer (STTR)
APPLICANT(S)	THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION on behalf of THE UNIVERSITY OF NEVADA, LAS VEGAS (Las Vegas, Nevada); INNOSENSE LLC (Torrance, California)
ASSIGNEE(S)	THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (Las Vegas, Nevada); INNOSENSE LLC (Torrance, California)
INVENTOR(S)	Pradip K. Bhowmik (Henderson, Nevada); Kisholoy Goswami (Redondo Beach, California); Maksudul M. Alam (Glendora, California); Haesook Han (Henderson, Nevada)
ABSTRACT	This disclosure provides fire retardant materials, including polymers that include at least one pyridinium salt moiety and at least one phosphine oxide moiety. In some cases, fire retardant polymers provided herein have the following structure:
FILED	Friday, August 28, 2015
APPL NO	15/507723
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 79/04 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 21/14 (20130101) Original (OR) Class
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10242439 — Contrast based imaging and analysis computer-implemented method to analyze pulse thermography data for nondestructive evaluation

US 10242439	Koshti
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Ajay M. Koshti (League City, Texas)
ABSTRACT	Methods and systems for analyzing and processing digital data comprising a plurality of infra-red (IR) video images acquired by a pulse thermography system are used to compute video data from the raw and smoothed video data acquired for the performance of non-destructive evaluation. New video data types computed may include but are not limited to contrast evolution data such as normalized contrast, converted contrast and normalized temperature contrast. Additionally, video data types computed comprise surface temperature, surface temperature rise and temperature simple contrast.
FILED	Wednesday, August 16, 2017
APPL NO	15/679020
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/72 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 5/007 (20130101) G06T 5/20 (20130101) G06T 7/001 (20130101) G06T 7/0006 (20130101) Original (OR) Class G06T 7/13 (20170101) G06T 7/50 (20170101) G06T 7/62 (20170101) G06T 2207/10016 (20130101) G06T 2207/10048 (20130101) G06T 2207/20076 (20130101) G06T 2207/20212 (20130101)
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10242806 — Solar fuels generator

US 10242806	Lewis et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Joint Center for Artificial Photosynthesis (JCAP) National Aeronautics and Space Administration (NASA)
APPLICANT(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S)	THE CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Nathan S. Lewis (La Canada Flintridge, California); Joshua M. Spurgeon (Los Angeles, California); William C. West (South Pasadena, California); Chengxiang Xiang (Pasadena, California)
ABSTRACT	The solar fuels generator includes an ionically conductive separator between a gaseous first phase and a second phase. A photoanode uses one or more components of the first phase to generate cations during operation of the solar fuels generator. A cation conduit is positioned provides a pathway along which the cations travel from the photoanode to the separator. The separator conducts the cations. A second solid cation conduit conducts the cations from the separator to a photocathode.
FILED	Thursday, May 17, 2018
APPL NO	15/982832
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/003 (20130101) C25B 9/08 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/20 (20130101) Original (OR) Class
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10243250 — Two-way microwave power divider

US 10243250	U-Yen et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Kongpop U-Yen (Alexandria, Virginia); Nathan Kovarik (Rapid City, South Dakota)
ABSTRACT	A two-way microwave power divider (the “power divider”) may include an input port and two output ports. The power divider may also include a junction that is configured to split a feedline from the input port into a first transmission line and a second transmission line. One or more resistors may be placed along the first transmission line and the second transmission line to provide isolation between the two output ports.
FILED	Tuesday, February 14, 2017
APPL NO	15/432569
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 5/184 (20130101) Original (OR) Class
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10243412 — Beamforming rectennas, systems and methods for wireless power transfer

US 10243412	Fink et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Patrick W. Fink (Missouri City, Texas); Gregory Y. Lin (Friendswood, Texas); Timothy F. Kennedy (Houston, Texas); Phong H. Ngo (Friendswood, Texas); Haley C. Boose (League City, Texas)
ABSTRACT	A passive beamforming rectenna includes a plurality of antennas, a plurality of terminal port rectifying circuits, and a beamforming network. The beamforming network includes (a) a plurality of antenna ports connecting to the plurality of antennas, and (b) a plurality of terminal ports connecting to the plurality of terminal port rectifying circuits. The beamforming network further includes a microwave lens or any of a variety of other structures. The beamforming rectenna is characterized by a plurality of radiation distribution patterns. Electromagnetic power is received through the plurality of antennas. The beamforming network directs the received electromagnetic power, in substantial portion, to a subset of the plurality of terminal ports associated with particular radiation distribution patterns whose amplitudes, in the direction from which the electromagnetic power was received, are large relative to the amplitudes, in the same direction, of other radiation distribution patterns associated with other terminal ports.
FILED	Thursday, August 25, 2016
APPL NO	15/247562
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 50/27 (20160201) Original (OR) Class Transmission H04B 7/04 (20130101) H04B 7/0456 (20130101) H04B 7/0617 (20130101)
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10243580 — Digital to analog converter with iterative stepping to each output value

US 10243580	Johnson
FUNDED BY	National Aeronautics and Space Administration (NASA) Goddard Space Flight Center (GSFC)
APPLICANT(S)	Southwest Research Institute (San Antonio, Texas)
ASSIGNEE(S)	SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas)
INVENTOR(S)	Mark A. Johnson (Spicewood, Texas)
ABSTRACT	A digital to analog converter (DAC) that provides an output that is iteratively stepped as the DAC increments or decrements from its digital input to analog output. The DAC has configurable registers to store a timer count value, an iteration value, and the input value. A state machine compares the iteration value to current DAC values, and adds or subtracts the iteration value until the final output is reached.
FILED	Monday, May 21, 2018
APPL NO	15/984623
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Coding; Decoding; Code Conversion in General H03M 1/82 (20130101) H03M 1/462 (20130101) Original (OR) Class
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10244628 — Printed electronics

US 10244628	Crain et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil and Mechanical Systems (CMS)
APPLICANT(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey); VORBECK MATERIALS CORPORATION (Jessup, Maryland)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey); VORBECK MATERIALS CORPORATION (Jessup, Maryland)
INVENTOR(S)	John M. Crain (Washington, District of Columbia); John S. Lettow (Washington, District of Columbia); Ilhan A. Aksay (Princeton, New Jersey); Sibel Korkut (Princeton, New Jersey); Katherine S. Chiang (Princeton, New Jersey); Chuan-Hua Chen (Princeton, New Jersey); Robert K. Prud'homme (Princeton, New Jersey)
ABSTRACT	Printed electronic device comprising a substrate onto at least one surface of which has been applied a layer of an electrically conductive ink comprising functionalized graphene sheets and at least one binder. A method of preparing printed electronic devices is further disclosed.
FILED	Monday, March 05, 2018
APPL NO	15/911623
ART UNIT	2816 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/02 (20130101) C01P 2006/12 (20130101) C01P 2006/40 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/46 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/65 (20180101) C09D 7/70 (20180101) C09D 11/037 (20130101) C09D 11/52 (20130101) C09D 11/102 (20130101) C09D 171/02 (20130101) C09D 177/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/092 (20130101) H05K 1/095 (20130101) Original (OR) Class H05K 3/12 (20130101) H05K 3/0091 (20130101) H05K 2201/0323 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/734 (20130101) Y10S 977/847 (20130101) Y10S 977/932 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

10238370 — Steerable shape sensing biopsy needle

US 10238370	Park et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Medical Research Acquisition Activity (USAMRAA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) Small Business Administration (SBA) Small Business Innovation Research (SBIR) Small Business Technology Transfer (STTR)
APPLICANT(S)	Intelligent Fiber Optic Systems, Inc (Santa Clara, California)
ASSIGNEE(S)	INTELLIGENT FIBER OPTIC SYSTEMS, INC. (Santa Clara, California)
INVENTOR(S)	Yong-Lae Park (Stanford, California); Richard James Black (Menlo Park, California); Behzad Moslehi (Los Altos, California); Mark R. Cutkosky (Palo Alto, California); Santhi Elayaperumal (Stanford, California); Bruce Daniel (Stanford, California); Alan Yeung (Stanford, California); Vahid Sotoudeh (Los Altos, California)
ABSTRACT	A biopsy needle has a central axis and includes one or more sensing regions, each sensing region formed by a plurality of sensing optical fibers located over a particular extent of said central axis and inside the outer shell of the needle. The sensing optical fibers are coupled to a wavelength interrogator. A steerable catheter has a central axis and outer shell, the outer shell coupled to a plurality of optical fibers in sensing regions and actuation regions, the sensing regions formed over particular extents of the central axis by bonding gratings to the inner surface of the outer shell, and the actuation regions formed by coupling optical energy into shape memory alloys bonded to the outer shell.
FILED	Friday, January 03, 2014
APPL NO	14/147486
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 10/0266 (20130101) Original (OR) Class A61B 2017/003 (20130101) A61B 2017/00106 (20130101) A61B 2034/2061 (20160201) A61B 2090/065 (20160201)
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10239878 — Macrocyclic ligands with pendant chelating moieties and complexes thereof

US 10239878	Tatum et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA)
APPLICANT(S)	LUMIPHORE, INC. (Berkeley, California)
ASSIGNEE(S)	LUMIPHORE, INC. (Berkeley, California)
INVENTOR(S)	David Tatum (Berkeley, California); Jide Xu (Richmond, California); Darren Magda (San Leandro, California); Nathaniel Butlin (Pacifica, California)
ABSTRACT	The invention relates to ligands and complexes of metal ions with the ligands useful in various applications, including therapeutic and diagnostic applications.
FILED	Wednesday, March 07, 2018
APPL NO	15/914945
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 51/0482 (20130101) Heterocyclic Compounds C07D 471/18 (20130101) Original (OR) Class C07D 491/22 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/182 (20130101) C09K 2211/1029 (20130101)
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10240090 — Fire retardant materials and devices including same

US 10240090	Bhowmik et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR) Small Business Technology Transfer (STTR)
APPLICANT(S)	THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION on behalf of THE UNIVERSITY OF NEVADA, LAS VEGAS (Las Vegas, Nevada); INNOSENSE LLC (Torrance, California)
ASSIGNEE(S)	THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (Las Vegas, Nevada); INNOSENSE LLC (Torrance, California)
INVENTOR(S)	Pradip K. Bhowmik (Henderson, Nevada); Kisholoy Goswami (Redondo Beach, California); Maksudul M. Alam (Glendora, California); Haesook Han (Henderson, Nevada)
ABSTRACT	This disclosure provides fire retardant materials, including polymers that include at least one pyridinium salt moiety and at least one phosphine oxide moiety. In some cases, fire retardant polymers provided herein have the following structure:
FILED	Friday, August 28, 2015
APPL NO	15/507723
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 79/04 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 21/14 (20130101) Original (OR) Class
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10241015 — Cryogenic cooling positioning apparatus, methods and applications

US 10241015	Hollabaugh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Mitegen, LLC (Ithaca, New York)
ASSIGNEE(S)	Mitegen, LLC (Ithaca, New York)
INVENTOR(S)	Stephen Hollabaugh (Ithaca, New York); Robert Newman (Groton, New York); David Closs (Freeville, New York)
ABSTRACT	A method and a cryogenic sample positioning system are provided which include: a sample holder cassette that is vertically coupled to a carousel gear through a first shaft. Each sample holder cassette has a first degree of rotation about the first shaft. A first planet drive gear underlies and is vertically coupled to the carousel gear through a second shaft that extends from the carousel gear through the first planet drive gear. The carousel gear has a second degree of rotation about the second shaft that is different from the first degree of rotation. A planet gear that is laterally connected to a second planet drive gear is interposed between each of the carousel gear and the first planet drive gear. Each of the planet gear and the second planet drive gear selectively define the first degree of rotation, without affecting the second degree of rotation of the carousel gear.
FILED	Monday, July 24, 2017
APPL NO	15/657988
ART UNIT	3655 — Material and Article Handling
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0242 (20130101) A01N 1/0257 (20130101) A01N 1/0268 (20130101) Gearing F16H 1/28 (20130101) F16H 57/08 (20130101) F16H 57/12 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 19/005 (20130101) Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 3/11 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/42 (20130101) Original (OR) Class G01N 23/20033 (20130101) G01N 35/025 (20130101) G01N 2035/0486 (20130101) G01N 2223/604 (20130101)
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Department of Agriculture (USDA)

10239905 — Low temperature and efficient fractionation of lignocellulosic biomass using recyclable organic solid acids

US 10239905	Zhu et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S)	Junyong Zhu (Madison, Wisconsin); Liheng Chen (Madison, Wisconsin); Roland Gleisner (Jefferson, Wisconsin)
ABSTRACT	Methods of fractionating lignocellulosic biomass using hydrotropic sulfonic acids are provided. Also provided are methods of forming lignin particles, furans, sugars, and/or lignocellulosic micro- and nanofibrils from the liquid and solid fractions produced by fractionation process. The fractionation can be carried out at low temperatures with short reaction times.
FILED	Monday, January 29, 2018
APPL NO	15/882078
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Compounds of Unknown Constitution C07G 1/00 (20130101) Original (OR) Class Derivatives of Natural Macromolecular Compounds C08H 8/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/04 (20130101) C12P 19/04 (20130101) C12P 2201/00 (20130101) Fibrous Raw Materials or Their Mechanical Treatment D21B 1/02 (20130101) D21B 1/04 (20130101) D21B 1/08 (20130101) D21B 1/38 (20130101) Treatment of the Materials Before Passing to the Paper-making Machine D21D 5/005 (20130101)
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10241037 — Laser sensor for trace gas detection

US 10241037	Yalin
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado)
ASSIGNEE(S)	Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S)	Azer P. Yalin (Fort Collins, Colorado)
ABSTRACT	Systems and methods are disclosed to determine the concentration of a species within a sample. An example method may include collecting optical loss data over a range of frequencies from the sample using a spectroscopy system; placing the optical loss data into a plurality of bins, each bin having a defined frequency width; determining an average optical loss data value for the optical loss values within each bin that have an optical loss value less than a threshold value; removing the optical loss data within each bin having a value outside a tolerance range bounding the average optical loss data value for the respective bin; fitting a spectral curve to the remaining optical loss data; and determining the concentration of the species within the sample based on the spectral curve.
FILED	Tuesday, October 20, 2015
APPL NO	15/520051
ART UNIT	2877 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 2003/423 (20130101) G01J 2003/2869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) G01N 21/3504 (20130101) Original (OR) Class G01N 2201/1248 (20130101)
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10241053 — Bacterial detection platform based on SERS mapping

US 10241053	He
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)	University of Massachusetts (Boston, Massachusetts)
INVENTOR(S)	Lili He (Belchertown, Massachusetts)
ABSTRACT	A bacterial detection platform integrating the sensitive SERS technique and the advanced mapping technique. Bacterial cells on the SERS substrate are detected using the mapping technique. The identification is based on the fingerprint of the bacterial SERS spectra. The quantification of the cells is based on the mapping technique. For different applications, silver or gold nanoparticles can be integrated onto a filter membrane for concentration and detection of bacterial cells in water or silver dendrites can be used as the SERS substrate. The SERS substrates are also modified with capturers and fixed in a vessel to concentrate cells from complex liquid matrices.
FILED	Friday, June 03, 2016
APPL NO	15/173098
ART UNIT	2886 — Optics
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) C12Q 1/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Original (OR) Class G01N 2333/32 (20130101)
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Department of Commerce (DOC)

10240194 — Methods for nucleotide sequencing and high fidelity polynucleotide synthesis

US 10240194	Jacobson et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Joseph Jacobson (Newton, Massachusetts); Daniel Schindler (Newton, Massachusetts)
ASSIGNEE(S)	Gen9, Inc. (Cambridge, Massachusetts)
INVENTOR(S)	Joseph Jacobson (Newton, Massachusetts); Daniel Schindler (Newton, Massachusetts)
ABSTRACT	Methods of obtaining sequence information about target polynucleotide having a predefined sequence are disclosed. The methods include sequencing by ligation and sequencing by polymerase.
FILED	Friday, May 13, 2011
APPL NO	13/697182
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 2521/101 (20130101) C12Q 2521/501 (20130101) C12Q 2525/121 (20130101) C12Q 2525/204 (20130101) C12Q 2533/107 (20130101) C12Q 2563/107 (20130101)
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10240998 — Determining a location and size of a gas source with a spectrometer gas monitor

US 10240998	Prasad et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia); The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia); The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S)	Kuldeep Prasad (Vienna, Virginia); Caroline Alden (Boulder, Colorado); Gregory Brian Rieker (Boulder, Colorado); Robert James Wright (Boulder, Colorado); Sean Coburn (Longmont, Colorado)
ABSTRACT	A process for determining a location and size of a gas source within an area with a spectrometer gas monitor includes: providing the spectrometer gas monitor; performing fence line monitoring of the area with the spectrometer gas monitor; collecting spectroscopic data over multiple open paths around the area with the spectrometer gas monitor; measuring atmospheric conditions along gas inflows and gas outflows of the area; subtracting a background for a selected gas from the spectroscopic data; applying a boundary constraint to the spectroscopic data; determining an atmospheric concentration of air entering the area; applying bootstrapping to the spectroscopic data; applying zero minimum elimination to the spectroscopic data; and producing inversion data from the spectroscopic data to determine the location and size of the gas source within the area.
FILED	Tuesday, October 10, 2017
APPL NO	15/729079
ART UNIT	2857 — Printing/Measuring and Testing
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/16 (20130101) Original (OR) Class G01M 3/22 (20130101) G01M 3/202 (20130101)
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10241149 — Massively parallel wafer-level reliability system and process for massively parallel wafer-level reliability testing

US 10241149	Cheung
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia)
INVENTOR(S)	Kin P. Cheung (Rockville, Maryland)
ABSTRACT	A massively parallel wafer-level reliability system to test a reliability of wafers includes: a test platform; stations disposed on the test platform, wherein an individual test station receives a wafer and includes: a chuck disposed on the test platform; a probe including contactors that electrically contact the wafer; and a temperature controller to control a temperature of the wafer; a control platform disposed among the test stations; and a system controller to independently control the test stations and that is in electrical communication with the temperature controller, wherein the reliability of the wafers is tested in parallel by the test stations.
FILED	Saturday, September 24, 2016
APPL NO	15/275345
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2855 (20130101) G01R 31/2874 (20130101) Original (OR) Class G01R 31/2894 (20130101)
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Department of Veterans Affairs (DVA)

10238641 — Materials and methods for diagnosis, prevention and/or treatment of stress disorders and conditions associated with A-beta peptide aggregation

US 10238641	Echeverria Moran
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia); University of South Florida (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida); The United States of America as represented by the Department of Veteran's Affairs (Washington, District of Columbia)
INVENTOR(S)	Valentina Echeverria Moran (Largo, Florida)
ABSTRACT	The subject invention concerns materials and methods for treating and/or preventing diseases associated with accumulation of Aβ peptide in neural tissue. The subject invention also concerns materials and methods for treating and/or preventing stress disorders, such as post-traumatic stress disorder (PTSD). In one embodiment, a method of the invention comprises administering a therapeutically effective amount of cotinine, or a pharmaceutically acceptable salt thereof, to a person or animal in need of treatment. The methods of the invention can be used to prevent and/or treat Alzheimer's disease, Parkinson's disease, and/or Down's syndrome. The subject invention also concerns compositions that comprise cotinine, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, diluent or adjuvant. The subject invention concerns materials and methods for detecting and diagnosing conditions associated with accumulation of Aβ peptide in neural tissue, such as Alzheimer's disease and Parkinson's disease, using the chemical cotinine. In one embodiment, the method comprises administering cotinine labeled with a detectable label to a person or animal. The presence of labeled cotinine in neural tissue is then determined. The level and/or location of cotinine can be analyzed and a diagnosis made. The subject invention also concerns cotinine labeled with a detectable label. In one embodiment, the cotinine is labeled with a radioisotope that can be detected by Positron Emission Tomography (PET) or single photon emission computed tomography (SPECT).
FILED	Wednesday, October 04, 2017
APPL NO	15/725079
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/4439 (20130101) Original (OR) Class A61K 51/0455 (20130101) Heterocyclic Compounds C07D 401/04 (20130101)
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10238742 — Cell penetrating nucleolytic antibody based cancer therapy

US 10238742	Hansen et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	Yale University (New Haven, Connecticut); The United States of America as represented by the Department of Veteran Affairs (Washington, District of Columbia)
ASSIGNEE(S)	Yale University (New Haven, Connecticut); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	James E. Hansen (Guilford, Connecticut); Richard H. Weisbart (Los Angeles, California); Philip W. Noble (New Haven, Connecticut)
ABSTRACT	Cancer cells with defects in DNA repair are highly susceptible to DNA-damaging agents, but delivery of therapeutic agents into cell nuclei can be challenging. A sub-set of autoantibodies having nucleolytic activity are capable of nuclear penetration. These antibodies can be used as therapeutic agents targeted towards DNA repair-deficient malignancies.
FILED	Thursday, June 25, 2015
APPL NO	14/750683
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Original (OR) Class Peptides C07K 16/44 (20130101) C07K 2317/73 (20130101) C07K 2317/77 (20130101)
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10238750 — Porphyrin modified telodendrimers

US 10238750	Lam et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Kit Lam (Davis, California); Yuanpei Li (Elk Grove, California); Chongxian Pan (Davis, California)
ABSTRACT	The present invention provides amphiphilic telodendrimers that aggregate to form nanocarriers characterized by a hydrophobic core and a hydrophilic exterior. The nanocarrier core may include amphiphilic functionality such as cholic acid or cholic acid derivatives, and the exterior may include branched or linear poly(ethylene glycol) segments. Nanocarrier cargo such as hydrophobic drugs and other materials may be sequester in the core via non-covalent means or may be covalently bound to the telodendrimer building blocks. Telodendrimer structure may be tailored to alter loading properties, interactions with materials such as biological membranes, and other characteristics.
FILED	Thursday, December 12, 2013
APPL NO	14/651860
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 41/0033 (20130101) A61K 41/0052 (20130101) A61K 41/0071 (20130101) A61K 41/0076 (20130101) A61K 47/60 (20170801) Original (OR) Class A61K 47/62 (20170801) A61K 47/6907 (20170801) A61K 47/6911 (20170801) A61K 49/0002 (20130101) A61K 49/0036 (20130101) A61K 49/0082 (20130101) A61K 49/0423 (20130101) A61K 49/1809 (20130101) A61K 51/1227 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101)
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National Security Agency (NSA)

10242090 — Method and device for measuring relevancy of a document to a keyword(s)

US 10242090	Kosloski et al.
FUNDED BY	National Security Agency (NSA)
APPLICANT(S)	National Security Agency (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia)
INVENTOR(S)	Jon T. Kosloski (Catonsville, Maryland); John W. Thompson (San Diego, California)
ABSTRACT	A method is presented for ranking documents identified in a search relative to a keyword. The method utilizes a set of training documents to provide a co-occurrence matrix and a transition matrix. A word pair relevancy measure is calculated for each word of the document to be ranked. These word pair relevancy measures are based upon the co-occurrence and transition matrices obtained from the training set and are utilized to calculate a document relevance measure. Documents identified in a search are ranked utilizing the document relevance measure.
FILED	Thursday, March 06, 2014
APPL NO	13/987283
ART UNIT	2163 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 17/30011 (20130101) G06F 17/30598 (20130101) G06F 17/30616 (20130101) G06F 17/30675 (20130101) Original (OR) Class G06F 17/30705 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) G06N 99/005 (20130101)
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10242425 — Translation of artificial intelligence representations

US 10242425	Riabov et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Anton V. Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (Port Chester, New York); Octavian Udrea (Ossining, New York)
ABSTRACT	Techniques for translating graphical representations of domain knowledge are provided. In one example, a computer-implemented method comprises receiving, by a device operatively coupled to a processor, a graphical representation of domain knowledge. The graphical representation comprises information indicative of a central concept and at least one chain of events associated with the central concept. The computer-implemented method further comprises translating, by the device, the graphical representation into an artificial intelligence planning problem. The artificial intelligence planning problem is expressed in an artificial intelligence description language. The translating comprises parsing the graphical representation into groupings of terms. A first grouping of terms of the grouping of terms comprises an event from the at least one chain of events and a second grouping of terms of the grouping of terms comprises the information indicative of the central concept. The computer-implemented method also comprises validating, by the device, the artificial intelligence planning problem.
FILED	Thursday, December 14, 2017
APPL NO	15/842252
ART UNIT	2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Electric Digital Data Processing G06F 15/18 (20130101) G06F 17/30277 (20130101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) Image Data Processing or Generation, in General G06T 1/20 (20130101) Original (OR) Class
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10243662 — Bias-based Mach-Zehnder modulation (MZM) systems

US 10243662	Li et al.
FUNDED BY	National Security Agency (NSA) Maryland Procurement Office (MPO)
APPLICANT(S)	HEWLETT PACKARD ENTERPRISE DEVELOPMEN LP (Houston, Texas)
ASSIGNEE(S)	Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S)	Cheng Li (Palo Alto, California); Jim Huang (Palo Alto, California); Ashkan Seyedi (Palo Alto, California); Marco Fiorentino (Palo Alto, California); Raymond G Beausoleil (Palo Alto, California)
ABSTRACT	One example includes a bias-based Mach-Zehnder modulation (MZM) system. The system includes a Mach-Zehnder modulator to receive and split an optical input signal and to provide an intensity-modulated optical output signal based on a high-frequency data signal to modulate a relative phase of the split optical input signal to transmit data and based on a bias voltage to modulate the relative phase of the split optical input signal to tune the Mach-Zehnder modulator. The system also includes a bias feedback controller to compare a detection voltage associated with the intensity-modulated output signal with a reference voltage to measure an extinction ratio associated with an optical power of the intensity-modulated optical output signal and to adjust the bias voltage based on the comparison to substantially maximize the extinction ratio.
FILED	Wednesday, May 27, 2015
APPL NO	15/566929
ART UNIT	2637 — Optical Communications
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0102 (20130101) G02F 1/0123 (20130101) G02F 1/225 (20130101) G02F 2001/212 (20130101) Transmission H04B 10/503 (20130101) Original (OR) Class
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Department of Transportation (USDOT)

10239153 — Inertia friction welding system for martensite-free joining of materials

US 10239153	Workman
FUNDED BY	Department of Transportation (USDOT) Federal Railroad Administration (FRA)
APPLICANT(S)	EDISON WELDING INSTITUTE, INC. (Columbus, Ohio)
ASSIGNEE(S)	Edison Welding Institute, Inc. (Columbus, Ohio)
INVENTOR(S)	David P. Workman (Dublin, Ohio)
ABSTRACT	A method for joining materials such as metal alloys that includes a first component, wherein the first component includes a first alloy having a known austenization temperature below which martensite forms when the component is heated and then cooled at a predetermined rate of cooling; a second component, wherein the second component includes a second alloy; and a welding apparatus operative to create a weld between the first and second components without crossing the austenization temperature of the first alloy. The method also includes the steps of validating the characteristics of the weld created between the first and second components in real-time during the welding process; modifying the welding apparatus to prepare the surface of the first component prior to welding to assure proper alignment of the first and second components; and/or physically modifying the second component to enhance the welding characteristics and durability thereof.
FILED	Tuesday, October 25, 2016
APPL NO	15/333880
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/129 (20130101) B23K 20/227 (20130101) Original (OR) Class B23K 20/233 (20130101) B23K 20/1205 (20130101) B23K 2101/26 (20180801) B23K 2103/04 (20180801) B23K 2103/12 (20180801)
VIEW PATENT	@ USPTO: Full Text PDF

10243646 — Performance-based link management communications

US 10243646	Zeng et al.
FUNDED BY	Department of Transportation (USDOT) Federal Aviation Administration (FAA) National Airspace System (NAS) Data Communications Program (DATACOMM)
APPLICANT(S)	The MITRE Corporation (McLean, Virginia)
ASSIGNEE(S)	The MITRE Corporation (McLean, Virginia)
INVENTOR(S)	Dongsong Zeng (Germantown, Maryland); John C. Gonda, III (Falls Church, Virginia)
ABSTRACT	Disclosed herein are system, method, and computer program product embodiments for utilizing parallel links to improve sub-network availability and latency performance for ATC traffic. An embodiment operates by receiving a generated message. The type of the generated message is determined, where the type is an air traffic control message or a non-air traffic control message. Based on the type of message, communication links are selected, where the communication links include parallel transmission links or a serial link. The method continues by copying the generated message and transmitting the copied message using the selected communication links. The method waits to receive an acknowledgement indicating receipt of the transmitted message. Upon identifying an acknowledgement, any of the copied messages not yet retransmitted are deleted.
FILED	Monday, August 17, 2015
APPL NO	14/827733
ART UNIT	2415 — Multiplex and VoIP
CURRENT CPC	Transmission H04B 7/18506 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 45/245 (20130101) H04L 47/26 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Classified Government Agency

10241292 — Ultra-fast and mechanically stable zoom lens

US 10241292	Staver
FUNDED BY	Classified Government Agency
APPLICANT(S)	BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Philip R Staver (Wilton, New Hampshire)
ABSTRACT	A zoom lens having unpowered optical elements changeably inserted between conventional powered optical zoom elements enables ultra-fast and mechanically stable stepped changes in zoom state.
FILED	Friday, December 09, 2016
APPL NO	15/374475
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 7/102 (20130101) Original (OR) Class G02B 15/02 (20130101) G02B 15/16 (20130101) G02B 27/646 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 13/34 (20130101) Pictorial Communication, e.g Television H04N 5/23248 (20130101) H04N 5/23296 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

U.S. State Government

10240163 — Increasing the content of long chain fatty acids in seed oil

US 10240163	Wang et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Basic Energy Sciences (BES) Energy Frontier Research Centers (EFRC) Center for Advanced Biofuel Systems (CABS) Materials Sciences and Engineering Division (MSE) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI) Division of Molecular and Cellular Biosciences (MCB) U.S. State Government State of Kansas Kansas Lipidomics Research Center (KLRC)
APPLICANT(S)	Donald Danforth Plant Science Center (St. Louis, Missouri); The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S)	Donald Danforth Plant Science Center (St. Louis, Missouri); The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S)	Xuemin Wang (St. Louis, Missouri); Maoyin Li (St. Louis, Missouri)
ABSTRACT	Provided are plants that express, or overexpress, a pPLAIIIδ protein. Constitutive or seed-specific expression of pPLAIIIδ protein in Arabidopsis increases seed oil content, the amount of C20 and C22 fatty acids, and the amount of C56, C58, and C60 triacylglycerols, effectively resulting in significantly higher oil yield per plant. Use of pPLAIIIδ is therefore an effective biotechnological tool to significantly increase plant yield, including oil, and the amount of high value long chain fatty acids in agricultural and horticultural crops, especially oilseed crops.
FILED	Friday, September 25, 2015
APPL NO	14/866125
ART UNIT	1662 — Plants
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 69/604 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/20 (20130101) C12N 15/8247 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6463 (20130101) Enzymes C12Y 301/01 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

10243582 — Interfacing between SFQ and NRZ data encodings

US 10243582	Herr
FUNDED BY
APPLICANT(S)	Quentin P. Herr (Ellicott City, Maryland)
ASSIGNEE(S)	NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S)	Quentin P. Herr (Ellicott City, Maryland)
ABSTRACT	Superconducting interface circuits and methods convert between non-return-to-zero (NRZ) encoded voltage signals and reciprocal quantum logic (RQL) compliant signals of opposite-polarity single flux quantum (SFQ) pulse pairs, and vice-versa, so as to provide high-speed NRZ input to, and output from, RQL computing circuitry.
FILED	Tuesday, March 27, 2018
APPL NO	15/937418
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Pulse Technique H03K 19/195 (20130101) Coding; Decoding; Code Conversion in General H03M 5/02 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, March 26, 2019.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190326.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital