FedInvent™ Patents

Patent Details for Tuesday, April 09, 2019

This page was updated on Monday, March 27, 2023 at 05:46 AM GMT

Department of Health and Human Services (HHS)

10251550 — Systems and methods for automated segmentation of retinal fluid in optical coherence tomography

US 10251550	Jia et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon)
ASSIGNEE(S)	Oregon Health and Science University (Portland, Oregon)
INVENTOR(S)	Yali Jia (Portland, Oregon); Jie Wang (Portland, Oregon)
ABSTRACT	Disclosed herein are methods and systems for the identification and characterization of fluid accumulation in the retina using OCT imaging. The disclosed methods and systems are directed to the automated segmentation of retinal fluid using 2D or 3D structural OCT scan images. Approaches for visualization and quantification of both intraretinal and subretinal fluid are presented. Methods are also disclosed for using OCT angiography data to improve the quality of retinal fluid segmentation, and to provide combined visualization of fluid accumulation and retinal vasculature to inform clinical interpretation of results.
FILED	Tuesday, March 14, 2017
APPL NO	15/458889
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/102 (20130101) Original (OR) Class A61B 3/1241 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6218 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 5/20 (20130101) G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 7/62 (20170101) G06T 11/003 (20130101) G06T 2207/10101 (20130101) G06T 2207/20212 (20130101) G06T 2207/30041 (20130101) G06T 2211/404 (20130101)
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10251552 — Methods and systems for reducing irritability in infants

US 10251552	Bloch-Salisbury et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	University of Massachusetts Medical School (Worcester, Massachusetts)
ASSIGNEE(S)	University of Massachusetts Medical School (Worcester, Massachusetts)
INVENTOR(S)	Elisabeth Bloch-Salisbury (Worcester, Massachusetts); David Paydarfar (Newton, Massachusetts)
ABSTRACT	Systems and methods according to the present concepts reduce irritability in infants, such as infants suffering from neonatal abstinence syndrome (NAS) or colic. According to one embodiment, a method for reducing irritability in an infant includes determining one or more physiological measurements from an infant. The one or more physiological measurements relate to a state of irritability in the infant. The method also includes determining the state of irritability based on the one or more physiological measurements and applying a stochastic stimulation to the infant based on the state of irritability. The stochastic stimulation may be applied via a mattress. The stochastic stimulation may be vibro-tactile or subsensory.
FILED	Tuesday, March 03, 2015
APPL NO	15/127744
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/00 (20130101) Original (OR) Class A61B 5/08 (20130101) A61B 5/11 (20130101) A61B 5/024 (20130101) A61B 5/02055 (20130101) A61B 5/4824 (20130101) A61B 5/4836 (20130101) A61B 5/6892 (20130101) A61B 2503/04 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/02 (20130101) A61H 23/0236 (20130101) A61H 2201/0146 (20130101) A61H 2201/0188 (20130101) A61H 2201/5048 (20130101) A61H 2201/5058 (20130101) A61H 2201/5061 (20130101) A61H 2201/5092 (20130101)
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10251592 — MRI-based systems and methods for determining function capacity of the kidney

US 10251592	Bennett et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Nephrodiagnostics LLC (Clayton, Missouri)
ASSIGNEE(S)	Nephrodiagnostics LLC (Clayton, Missouri)
INVENTOR(S)	Kevin Michael Bennett (Honolulu, Hawaii); Scott Charles Beeman (St. Louis, Missouri)
ABSTRACT	Systems and methods for noninvasively determining the function capacity of the kidney are provided. In the methods, first contrast agent is injected into the vasculature of a subject. The contrast agent is to be bound with functioning glomeruli of the kidney of the subject. Then, the kidney is imaged with a magnetic resonance imaging (MRI) system to acquire MRI images of the kidney. In the images, signal magnitudes or phases of voxels of regions bound with the contrast agent are different from signal magnitudes or phases of voxels of regions not bound with the contrast agent. Afterwards, the function capacity of the kidney is determined using the MRI images. Lastly, a report of the function capacity of the kidney is generated.
FILED	Wednesday, June 17, 2015
APPL NO	14/742272
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/201 (20130101) Original (OR) Class A61B 5/4222 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/14 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5601 (20130101) G01R 33/5608 (20130101)
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10251657 — Noninvasive fragmentation of urinary tract stones with focused ultrasound

US 10251657	Maxwell et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	University of Washington through its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S)	University of Washington through its Center for Commercialization (Seattle, Washington)
INVENTOR(S)	Adam D. Maxwell (Woodinville, Washington); Bryan W. Cunitz (Seattle, Washington); Wayne Kreider (Seattle, Washington); Oleg A. Sapozhnikov (Seattle, Washington); Ryan S. Hsi (Seattle, Washington); Michael R. Bailey (Seattle, Washington)
ABSTRACT	Methods, computing devices, and a computer-readable medium are described herein related to fragmenting or comminuting an object in a subject using a burst wave lithotripsy (BWL) waveform. A computing device, such a computing device coupled to a transducer, may carry out functions for producing a BWL waveform. The computing device may determine a burst frequency for a number of bursts in the BWL waveform, where the number of bursts includes a number of cycles. Further, the computing device may determine a cycle frequency for the number of cycles. Yet further, the computing device may determine a pressure amplitude for the BWL waveform, where the pressure amplitude is less than or equal to 8 MPa. In addition, the computing device may determine a time period for producing the BWL waveform.
FILED	Friday, May 02, 2014
APPL NO	14/268414
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/22012 (20130101) Original (OR) Class A61B 2017/22014 (20130101)
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10251750 — Systems and methods for improving cardiac function

US 10251750	Alexander et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Edwards Lifesciences Corporation (Irvine, California)
ASSIGNEE(S)	Edwards Lifesciences Corporation (Irvine, California)
INVENTOR(S)	Miles D. Alexander (Menlo Park, California); Matthew L. Pease (Mountain View, California); Barry L. Templin (Menlo Park, California); Serjan D. Nikolic (San Francisco, California)
ABSTRACT	A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge. Devices and methods are described herein which are directed to the treatment of a patient's heart having, or one which is susceptible to heart failure, to improve diastolic function.
FILED	Thursday, June 22, 2017
APPL NO	15/630601
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/0057 (20130101) A61B 17/12022 (20130101) A61B 17/12122 (20130101) A61B 17/12172 (20130101) A61B 2017/00243 (20130101) A61B 2017/00575 (20130101) A61B 2017/00579 (20130101) A61B 2017/00592 (20130101) A61B 2017/00597 (20130101) A61B 2017/00615 (20130101) A61B 2017/00632 (20130101) A61B 2017/0649 (20130101) A61B 2017/00867 (20130101) A61B 2017/12095 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2487 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/10 (20130101) A61M 1/12 (20130101) A61M 1/122 (20140204) A61M 1/1003 (20140204) A61M 1/1008 (20140204) A61M 1/1068 (20130101) A61M 2205/32 (20130101)
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10251778 — Therapeutics dispensing device and methods of making same

US 10251778	Acharya et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Baylor College of Medicine (Houston, Texas); REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	Baylor College of Medicine (Houston, Texas); REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Ghanashyam Acharya (Houston, Texas); Stephen C. Pflugfelder (Houston, Texas); Cintia S. De Paiva (Houston, Texas); Jennifer L. Simpson (Irvine, California)
ABSTRACT	A therapeutics delivery system, and methods of making and using same, are disclosed for environments that rapidly clear any injected therapeutics, such as a patient's eye. The therapeutics delivery system releases the drug in a therapeutically effective concentration for a desired duration of time with a predefined drug kinetics. In one embodiment, the embodiments of the present disclosure release a therapeutically effective concentration for a longer time period than other delivery systems, for instance from a day to a week. Certain embodiments comprise a therapeutics dispensing device comprising a biodissolvable hydrogel matrix for long term drug release that allows the device to be placed directly at the injured site, e.g., onto the surface at or near the injury, and retained there rather than through injection, whether locally or systematically.
FILED	Tuesday, August 06, 2013
APPL NO	14/420295
ART UNIT	3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Original (OR) Class A61F 2210/0004 (20130101) A61F 2240/005 (20130101) A61F 2250/0068 (20130101) A61F 2310/00383 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0051 (20130101) A61K 47/32 (20130101) A61K 47/34 (20130101) A61K 47/42 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/3842 (20130101) B29C 39/02 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/712 (20130101)
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10251852 — Composition and methods for treatment of lung disorders characterized by cholesterol dysregulation

US 10251852	Trapnell et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Children's Hospital Medical Center (Cincinnati, Ohio)
ASSIGNEE(S)	Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S)	Bruce Trapnell (Mariemont, Ohio); Tony Sallese (Eaton, Ohio); Brenna Carey (Cincinnati, Ohio); Takuji Suzuki (Midori, Japan)
ABSTRACT	Disclosed are compositions and methods for treating a condition characterized by a dysregulation in macrophage lipid homeostasis. The disclosed methods may include the administration of an agent selected from a PPARγ agonist, a LXR agonist, or a combination thereof. In certain aspects, the disclosed methods may be used to prevent, treat, or ameliorate conditions such as pulmonary alveolar proteinosis (PAP) and/or symptoms associated therewith.
FILED	Tuesday, April 11, 2017
APPL NO	15/484284
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/007 (20130101) A61K 9/08 (20130101) A61K 9/0053 (20130101) A61K 31/18 (20130101) Original (OR) Class A61K 31/4439 (20130101) A61K 47/10 (20130101) A61K 47/26 (20130101)
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10251860 — Compounds for bone healing

US 10251860	Epperly et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Michael W. Epperly (Pittsburgh, Pennsylvania); Joel S. Greenberger (Sewickley, Pennsylvania); Peter Wipf (Pittsburgh, Pennsylvania); Julianne Glowacki (Boston, Massachusetts)
ABSTRACT	Disclosed herein are embodiments of a method of accelerating bone healing in a subject in need thereof, comprising administering to the subject a compound disclosed here. The method may further comprise selecting or identifying a subject that has bone damage, or is a risk of developing bone damage. The compound may be administered after bone damage has occurred, or it may be administered prophylactically. The compound may be administered to a subject that has not and/or will not be exposed to radiation. In other embodiments, the subject has been and/or will be exposed to radiation.
FILED	Tuesday, February 27, 2018
APPL NO	15/906856
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/00 (20180101) A61P 19/10 (20180101) Heterocyclic Compounds C07D 305/06 (20130101)
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10251869 — Compositions and methods of inhibiting metallo-β-lactamases

US 10251869	Bonomo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Robert Bonomo (Cleveland, Ohio); Alejandro Jose Vila (Sante Fe, Argentina); S. Graciela Mahler (Montevideo, Uruguay)
ABSTRACT	A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one β-lactam antibiotic and at least one bisthiazolidine metallo-β-lactamase inhibitor.
FILED	Monday, March 20, 2017
APPL NO	15/463952
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/407 (20130101) A61K 31/407 (20130101) A61K 31/429 (20130101) Original (OR) Class A61K 31/429 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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10251870 — Method for treating obesity, diabetes, cardiovascular and kidney diseases by regulating GPR30/GPER activity

US 10251870	Prossnitz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Eric R. Prossnitz (Albuquerque, New Mexico); Matthias Barton (Zurich, Switzerland); Matthias R. Meyer (Stallikon, Switzerland)
ABSTRACT	The current invention is in the field of molecular biology/pharmacology and provides methods of using compounds that modulate the effects of GPR30/GPER for treating obesity and diabetes (preferably agonists) as well as disease states and/or conditions that result from excessive formation of reactive oxygen species (preferably antagonists). These compounds may function as agonists and/or antagonists of the disclosed estrogen receptor and/or modulate the expression/upregulation of nox and nox-associated reactive oxygen species (ROS).
FILED	Wednesday, March 02, 2016
APPL NO	15/556055
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/16 (20130101) A61K 31/435 (20130101) A61K 31/436 (20130101) Original (OR) Class A61K 31/437 (20130101) A61K 31/4355 (20130101) A61K 31/7088 (20130101) A61K 38/28 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/042 (20130101)
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10251871 — Compositions and methods for treatment of edema

US 10251871	Mehrara et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Memorial Sloan Kettering Cancer Center (New York, New York)
ASSIGNEE(S)	Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S)	Babak Mehrara (Chappaqua, New York); Jason Gardenier (Altona, New York); Ira Savetsky (Cedarhurst, New York); Omer Aras (New York, New York)
ABSTRACT	Provided are pharmaceutical compositions and methods of treating or preventing edema, using an anti-T cell agent, an anti-TGF-β1 agent, or an anti-angiotensin agent, preferably a combination of at least two such agents. The pharmaceutical compositions can be formulated for systemic or local administration, and are preferably administered topically.
FILED	Friday, February 05, 2016
APPL NO	15/549156
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0014 (20130101) A61K 31/42 (20130101) A61K 31/277 (20130101) A61K 31/401 (20130101) A61K 31/436 (20130101) A61K 31/4412 (20130101) Original (OR) Class A61K 38/13 (20130101) A61K 38/13 (20130101) A61K 47/10 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/10 (20180101)
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10251878 — Polysubunit opioid prodrugs resistant to overdose and abuse

US 10251878	Jenkins
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Elysium Therapeutics, Inc. (San Ramon, California)
ASSIGNEE(S)	Elysium Therapeutics, Inc. (Danville, California)
INVENTOR(S)	Thomas E. Jenkins (Half Moon Bay, California)
ABSTRACT	The invention provides compositions and methods for the treatment or prevention of pain. The invention provides constructs whereby hydrolysis of the construct by a specified gastrointestinal enzyme directly, or indirectly, releases an opioid when taken orally as prescribed. The gastrointestinal enzyme mediated release of opioid from constructs of the invention is designed to be attenuated in vivo via a saturation or inhibition mechanism when overdoses are ingested. The invention further provides constructs that are highly resistant to oral overdose, chemical tampering, and abuse via non-oral routes of administration.
FILED	Tuesday, August 22, 2017
APPL NO	15/683356
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) Original (OR) Class A61K 47/55 (20170801) A61K 47/61 (20170801) A61K 47/64 (20170801)
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10251887 — Methods and compositions to reduce oxidative stress

US 10251887	Messina
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)	University of Massachusetts (Boston, Massachusetts)
INVENTOR(S)	Louis M. Messina (Westborough, Massachusetts)
ABSTRACT	The invention relates to therapeutic applications for compositions that reduce the level of oxidative stress on cells in vivo or in vitro. The invention describes methods for improving the therapeutic properties of stem cells. The invention also provides combination therapies that are useful to balance the oxidative microenvironment of cells in vivo or in vitro.
FILED	Tuesday, February 21, 2017
APPL NO	15/438244
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) A61K 31/198 (20130101) A61K 31/375 (20130101) A61K 31/375 (20130101) A61K 31/495 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 35/13 (20130101) A61K 45/06 (20130101) A61K 48/005 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2799/022 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 13/10 (20130101)
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10251906 — Compositions and methods for inducing apoptosis

US 10251906	Kopecek et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S)	UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Georgia)
INVENTOR(S)	Jindrich Henry Kopecek (Salt Lake City, Utah); Jiyuan Yang (Salt Lake City, Utah); Te-Wei Chu (Salt Lake City, Utah)
ABSTRACT	In an aspect, the invention relates to compositions, methods, and kits for inducing apoptosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED	Tuesday, March 11, 2014
APPL NO	14/773791
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/712 (20130101) Original (OR) Class A61K 47/58 (20170801) A61K 47/6807 (20170801) A61K 47/6849 (20170801) A61K 47/6897 (20170801) A61K 2039/505 (20130101) Peptides C07K 16/2887 (20130101) C07K 2317/35 (20130101) C07K 2317/40 (20130101) C07K 2317/55 (20130101) C07K 2317/73 (20130101)
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10251912 — MHC class II restricted T cell epitopes from the cancer antigen, NY ESO-1

US 10251912	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Rong-Fu Wang (Houston, Texas); Steven A. Rosenberg (Potomac, Maryland); Gang Zeng (Germantown, Maryland)
ABSTRACT	The present invention discloses the identification and isolation of novel MHC class II epitopes derived from the cancer antigen, NY ESO-1. The novel MHC class II epitopes from NY-EsO-1 are recognized by CD4⁺ T lymphocytes in an HLA class II restricted manner, in particular HLA-DR or HLA-DP restricted. The products of the gene are promising candidates for immunotherapeutic strategies for the prevention, treatment and diagnosis of patients with cancer.
FILED	Friday, August 19, 2016
APPL NO	15/241996
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2217/05 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 38/08 (20130101) A61K 39/00 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 2039/53 (20130101) Peptides C07K 7/06 (20130101) C07K 14/4748 (20130101) C07K 16/30 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2799/021 (20130101)
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10251914 — Compositions and methods for transplantation of colon microbiota

US 10251914	Sadowsky et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S)	Michael J. Sadowsky (Roseville, Minnesota); Alexander Khoruts (Golden Valley, Minnesota); Alexa R. Weingarden (St. Paul, Minnesota); Matthew J. Hamilton (Burnsville, Minnesota)
ABSTRACT	The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
FILED	Monday, June 19, 2017
APPL NO	15/626880
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 9/0053 (20130101) A61K 9/1617 (20130101) A61K 9/1623 (20130101) A61K 35/24 (20130101) A61K 35/24 (20130101) A61K 35/37 (20130101) Original (OR) Class A61K 35/74 (20130101) A61K 35/74 (20130101) A61K 35/741 (20130101) A61K 35/742 (20130101) A61K 45/06 (20130101) A61K 47/08 (20130101) A61K 47/26 (20130101) A61K 2035/11 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) Y02A 50/475 (20180101)
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10251922 — Newcastle disease viruses and uses thereof

US 10251922	Palese et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Icahn School of Medicine at Mount Sinai (New York, New York); Memorial Sloan Kettering Cancer Center (New York, New York)
ASSIGNEE(S)	Icahn School of Medicine at Mount Sinai (New York, New York); Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S)	Peter Palese (New York, New York); Adolfo Garcia-Sastre (New York, New York); Dmitriy Zamarin (New York, New York); Jedd D. Wolchok (New York, New York)
ABSTRACT	Described herein are chimeric Newcastle disease viruses engineered to express an agonist of a co-stimulatory signal of an immune cell and compositions comprising such viruses. Also described herein are chimeric Newcastle disease viruses engineered to express an antagonist of an inhibitory signal of an immune cell and compositions comprising such viruses. The chimeric Newcastle disease viruses and compositions are useful in the treatment of cancer. In addition, described herein are methods for treating cancer comprising administering Newcastle disease viruses in combination with an agonist of a co-stimulatory signal of an immune and/or an antagonist of an inhibitory signal of an immune cell.
FILED	Friday, October 20, 2017
APPL NO	15/789539
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/768 (20130101) Original (OR) Class A61K 39/3955 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 16/2878 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/18121 (20130101) C12N 2760/18122 (20130101) C12N 2760/18132 (20130101) C12N 2760/18133 (20130101) C12N 2760/18143 (20130101)
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10251931 — Cyclic peptides and methods using same

US 10251931	Chaiken et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	DREXEL UNIVERSITY (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S)	Irwin M. Chaiken (Gladwyne, Pennsylvania); Adel Ahmed Rashad Ahmed (Philadelphia, Pennsylvania)
ABSTRACT	The present invention includes novel cyclic peptides, and methods of using the same. The present invention further includes novel cyclic peptides conjugated with a gold nanoparticle, and methods of using the same.
FILED	Wednesday, December 09, 2015
APPL NO	15/533075
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 38/00 (20130101) A61K 38/12 (20130101) Original (OR) Class Peptides C07K 7/56 (20130101) C07K 7/60 (20130101)
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10251948 — Anti-HIV vaccine constructed based on amino acid mutations in attenuated live EIAV vaccine

US 10251948	Shao et al.
FUNDED BY	Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC)
APPLICANT(S)	NATIONAL CENTER FOR AIDS/STD CONTROL AND PREVENTION, CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION (Beijing, China PRC)
ASSIGNEE(S)	National Center for AIDS/STD Control And Prevention, Chinese Center for Disease Control and Prevention (Beijing, China PRC)
INVENTOR(S)	Yiming Shao (Beijing, China PRC); Lianxing Liu (Beijing, China PRC); Rongxian Shen (Heilongjiang, China PRC)
ABSTRACT	Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.
FILED	Wednesday, January 21, 2015
APPL NO	14/602065
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/57 (20130101) A61K 2039/545 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) C07K 16/1063 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101)
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10251955 — Heparin-mimicking sulfonated reverse thermal gel for the delivery of heparin-binding therapeutic proteins

US 10251955	Park et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Regents of the University of Colorado, A Body Corporate (Denver, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S)	Daewon Park (Englewood, Colorado); Brisa Pena-Castellanos (Aurora, Colorado)
ABSTRACT	A heparin-mimicking sulfonated reverse thermal gel (SRTG) as a heparin-binding therapeutic protein delivery system. This system is designed to turn from low viscous liquid to a physical gel by exposure to body temperature alone. This allows direct deployment through a small gauge needle or catheter at target area with minimal surgical intervention. A unique aspect of this system is that it possesses a net negative charge due to the presence of sulfonate groups. This allows the SRTG to mimic heparin function, binding and preserving the bioactivity of positively charged therapeutic proteins, providing localized and sustained release of such proteins.
FILED	Monday, July 10, 2017
APPL NO	15/645384
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 38/385 (20130101) A61K 47/34 (20130101) Original (OR) Class
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10251977 — Compositions and methods for tissue repair with extracellular matrices

US 10251977	Christman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) NIH Office of the Director (NIHOD)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Karen Christman (San Diego, California); Jessica DeQuach (La Jolla, California)
ABSTRACT	Described herein are compositions comprising decellularized extracellular matrix derived from skeletal muscle or other suitable tissue, and therapeutic uses thereof. Methods for treating, repairing or regenerating defective, diseased, damage, ischemic, ulcer cells, tissues or organs in a subject preferably a human, with diseases, such as PAD and CLI, using a decellularized extracellular matrix of the invention are provided. Methods of preparing culture surfaces and culturing cells with absorbed decellularized extracellular matrix are provided.
FILED	Wednesday, October 19, 2016
APPL NO	15/297535
ART UNIT	1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 35/34 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/14 (20130101) A61L 27/24 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/38 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/3633 (20130101) Original (OR) Class A61L 27/3886 (20130101) A61L 2400/06 (20130101) A61L 2430/30 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101)
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10252066 — Miniaturized wireless ultrasound energy transfer system for powering a bio-implantable medical device

US 10252066	Radziemski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Piezo Energy Technologies LLC (Tucson, Arizona)
ASSIGNEE(S)	Piezo Energy Technologies LLC (Tucson, Arizona)
INVENTOR(S)	Leon J. Radziemski (Tucson, Arizona); Inder Raj Singh Makin (Mesa, Arizona); Harry Jabs (Oakland, California); Juan Carlos Lopez Tonazzi (Tucson, Arizona)
ABSTRACT	A system for providing energy to a bio-implantable medical device includes an acoustic energy delivery device and a bio-implantable electroacoustical energy converter. The acoustic energy delivery device generates acoustic energy with a multi-dimensional array of transmitting electroacoustical transducers. The acoustic energy is received by one or more receiving electroacoustical transducers in the bio-implantable electroacoustical energy converter. The receiving electroacoustical transducers convert the acoustic energy to electrical energy to power the bio-implantable medical device directly or indirectly. An external alignment system provides lateral and/or angular positioning of an ultrasound energy transmitter over an ultrasound energy receiver. The acoustic energy transmitter alignment system comprises either or both x-y-z plus angular positioning components, and/or a substantially multi-dimensional array of transmitters plus position sensors in both the transmitter and receiver units.
FILED	Friday, May 05, 2017
APPL NO	15/587815
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/4041 (20130101) A61B 2560/0219 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/025 (20130101) A61N 1/3787 (20130101) Original (OR) Class A61N 1/37223 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/15 (20160201)
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10252100 — Biomechanical foot guidance linkage

US 10252100	Nelson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	NUtech Ventures (Lincoln, Nebraska); Madonna Rehabilitation Hospital (Lincoln, Nebraska)
ASSIGNEE(S)	NUTECH VENTURES (Lincoln, Nebraska); MADONNA REHABILITATION HOSPITAL (Lincoln, Nebraska)
INVENTOR(S)	Carl A. Nelson (Lincoln, Nebraska); Cale J. Stolle (Lincoln, Nebraska); Judith M. Burnfield (Lincoln, Nebraska)
ABSTRACT	A gait replication apparatus can include a scalable mechanical mechanism configured to replicate different gaits. The scalable mechanical mechanism can include, for example, a four-bar linkage, a pantograph, a cam/Scotch-yoke mechanism, and so forth. In some embodiments, the mechanical mechanism includes a beam rotating about an axis passing proximate to its center, with a foot pedal slidably coupled with the beam, and a timing chain/belt or cable pulley-pair coupled with the foot pedal and looped about the beam. A method can include decomposing a foot path defined by Cartesian coordinates into polar coordinates, and providing a mechanical support for a foot, where a first mechanism controls an angular position of the mechanical support with respect to a reference frame, and a second mechanism controls a radial distance of the mechanical support from the reference frame.
FILED	Thursday, October 20, 2016
APPL NO	15/299031
ART UNIT	3784 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 99/00 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/22 (20130101) A63B 21/154 (20130101) A63B 21/4034 (20151001) Original (OR) Class A63B 21/4035 (20151001) A63B 22/0664 (20130101) A63B 23/0476 (20130101) A63B 2022/067 (20130101)
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10252266 — Microfluidic siphoning array for nucleic acid quantification

US 10252266	Hung et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) NIH Office of the Director (NIHOD) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Combinati Incorporated (Palo Alto, California)
ASSIGNEE(S)	COMBINATI INCORPORATED (Palo Alto, California)
INVENTOR(S)	Ju-Sung Hung (Palo Alto, California); Andrew Zayac (San Leandro, California); Megan Dueck (Brisbane, California)
ABSTRACT	In some aspects, the present disclose provides methods for amplifying and quantifying nucleic acids. Methods for amplifying and quantifying nucleic acids comprise isolating a sample comprising nucleic acid molecules into a plurality of microchambers, performing a polymerase chain reaction on the plurality of microchambers, and analyzing the results of the polymerase chain reaction. In some aspects, the present disclosure provides devices consistent with the methods herein.
FILED	Tuesday, July 03, 2018
APPL NO	16/026827
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 7/52 (20130101) B01L 2200/0605 (20130101) B01L 2300/18 (20130101) B01L 2300/0609 (20130101) B01L 2300/0851 (20130101) B01L 2300/0864 (20130101) B01L 2400/049 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 2563/159 (20130101) C12Q 2565/629 (20130101)
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10252268 — Automated driving of an assay

US 10252268	Linbeck, III et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	fannin partners llc (Houston, Texas)
ASSIGNEE(S)	Fannin Partners LLC (Houston, Texas)
INVENTOR(S)	Leo Linbeck, III (Houston, Texas); Michael John Heffernan (Katy, Texas); Dev Chatterjee (Saint Louis, Missouri)
ABSTRACT	The invention herein relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. The assay cartridge includes magnetic beads, sample and control solutions in some wells, and assay reagents in others. A microcomputer controls a DC motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoding to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient.
FILED	Monday, December 26, 2016
APPL NO	15/390650
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 2200/027 (20130101) B01L 2200/0668 (20130101) B01L 2200/0673 (20130101) B01L 2300/021 (20130101) B01L 2300/087 (20130101) B01L 2300/0816 (20130101) B01L 2300/0858 (20130101) B01L 2300/0864 (20130101) B01L 2400/043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 33/54333 (20130101)
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10252270 — Nozzle apparatus and methods for use thereof

US 10252270	Weierstall et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI)
APPLICANT(S)	Uwe Weierstall (Phoenix, Arizona); Dingjie Wang (Tempe, Arizona); John Spence (Tempe, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Uwe Weierstall (Phoenix, Arizona); Dingjie Wang (Tempe, Arizona); John Spence (Tempe, Arizona)
ABSTRACT	Nozzle Assemblies and methods of use for producing a liquid jet are disclosed that may be permit adjustable time delays between mixing of fluids and observation of reactions. An example nozzle assembly includes: a housing having an inlet and an outlet and a first channel defined therebetween, where the housing includes a gas focusing aperture defining the housing outlet; an intermediate tube disposed within the first channel of the housing, where the intermediate tube has an inlet and an outlet and defines a second channel therebetween; and a central tube disposed within the second channel of the intermediate tube, where the central tube has an inlet and an outlet and defines a third channel therebetween, where the central tube outlet is longitudinally spaced apart from the intermediate tube outlet such that the intermediate tube outlet is disposed between the central tube outlet and the gas focusing aperture's inlet.
FILED	Tuesday, September 08, 2015
APPL NO	15/509376
ART UNIT	3752 — Fluid Handling and Dispensing
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0865 (20130101) B01F 3/04007 (20130101) B01F 5/045 (20130101) B01F 13/0062 (20130101) B01F 13/0093 (20130101) B01F 2215/0037 (20130101) B01F 2215/0431 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502776 (20130101) Original (OR) Class B01L 2200/0636 (20130101) B01L 2300/0832 (20130101) B01L 2300/0858 (20130101) B01L 2300/0867 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/32 (20130101)
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10252289 — Nanoparticle coating of surfaces

US 10252289	Hoerr et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Science Foundation (NSF)
APPLICANT(S)	Nanocopoeia, Inc. (St. Paul, Minnesota)
ASSIGNEE(S)	NANOCOPOEIA, INC. (St. Paul, Minnesota)
INVENTOR(S)	Robert A. Hoerr (Shoreview, Minnesota); John V. Carlson (St. Michael, Minnesota)
ABSTRACT	A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
FILED	Friday, August 14, 2015
APPL NO	14/826644
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 2300/41 (20130101) A61L 2300/45 (20130101) A61L 2300/404 (20130101) A61L 2300/416 (20130101) A61L 2300/602 (20130101) A61L 2300/624 (20130101) A61L 2400/12 (20130101) A61L 2420/02 (20130101) A61L 2420/06 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 5/03 (20130101) B05B 5/08 (20130101) B05B 5/025 (20130101) B05B 7/061 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/04 (20130101) B05D 1/06 (20130101) Original (OR) Class B05D 1/34 (20130101) B05D 1/36 (20130101) B05D 7/54 (20130101) B05D 2258/00 (20130101) B05D 2401/32 (20130101) B05D 2451/00 (20130101) B05D 2451/00 (20130101)
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10253033 — De novo synthesis of bacteriochlorins

US 10253033	Kim et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S)	North Carolina State University (Raleigh, North Carolina)
INVENTOR(S)	Han-Je Kim (Raleigh, North Carolina); Jonathan S. Lindsey (Raleigh, North Carolina)
ABSTRACT	A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
FILED	Monday, November 20, 2017
APPL NO	15/817973
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/555 (20130101) Heterocyclic Compounds C07D 207/335 (20130101) C07D 487/22 (20130101) Original (OR) Class Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 47/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101)
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10253035 — Eis inhibitors

US 10253035	Garneau-Tsodikova et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S)	University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S)	Sylvie Garneau-Tsodikova (Lexington, Kentucky); Oleg V. Tsodikov (Lexington, Kentucky)
ABSTRACT	Compounds and compositions are disclosed, which are useful as inhibitors of acetyltransferase Eis, a mediator of kanamycin resistance in Mycobacterium tuberculosis.
FILED	Friday, December 08, 2017
APPL NO	15/836666
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Acyclic or Carbocyclic Compounds C07C 47/575 (20130101) C07C 217/58 (20130101) Heterocyclic Compounds C07D 209/38 (20130101) C07D 211/52 (20130101) C07D 241/44 (20130101) C07D 275/03 (20130101) C07D 333/80 (20130101) C07D 487/04 (20130101) C07D 491/10 (20130101) C07D 491/048 (20130101) Original (OR) Class C07D 491/113 (20130101)
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10253039 — Inhibitors of bacterial DNA gyrase with efficacy against gram-negative bacteria

US 10253039	Shaw et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) NIH Office of the Director (NIHOD)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Jared T. Shaw (Davis, California); Jared T. Moore (Healdsburg, California); Molly R. Fensterwald (San Jose, California); Douglas B. Weibel (Madison, Wisconsin); Katherine A. Hurley (Madison, Wisconsin)
ABSTRACT	The present invention provides N-benzyl-3-sulfonamidopyrrolidines and related compounds, as well as pharmaceutical compositions and sanitizing compositions containing the same. The compounds and compositions are useful as antibiotic agents. Methods for making and using the compounds and compositions are also described.
FILED	Friday, November 11, 2016
APPL NO	15/349962
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/427 (20130101) A61K 31/435 (20130101) A61K 31/435 (20130101) A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/706 (20130101) A61K 31/706 (20130101) A61K 31/4025 (20130101) A61K 31/4155 (20130101) A61K 31/4178 (20130101) A61K 31/4192 (20130101) A61K 31/4365 (20130101) A61K 31/4439 (20130101) A61K 31/4709 (20130101) A61K 31/7048 (20130101) A61K 31/7048 (20130101) A61K 31/7052 (20130101) A61K 31/7052 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 207/14 (20130101) C07D 401/10 (20130101) C07D 401/12 (20130101) C07D 403/06 (20130101) C07D 403/10 (20130101) C07D 403/12 (20130101) C07D 405/06 (20130101) C07D 405/12 (20130101) C07D 409/10 (20130101) C07D 409/12 (20130101) C07D 417/06 (20130101) C07D 417/10 (20130101) C07D 471/04 (20130101) C07D 495/04 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) Y02A 50/481 (20180101)
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10253044 — 9H-pyrimido [4,5-b]indoles and related analogs as BET bromodomain inhibitors

US 10253044	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Shaomeng Wang (Superior Township, Michigan); Yujun Zhao (Ann Arbor, Michigan); Bing Zhou (Ann Arbor, Michigan); Angelo Aguilar (Ann Arbor, Michigan); Liu Liu (Ann Arbor, Michigan); Longchuan Bai (Ann Arbor, Michigan); Donna McEachern (Ann Arbor, Michigan); Duxin Sun (Ann Arbor, Michigan); Bo Wen (Ann Arbor, Michigan); Ruijuan Luo (Ann Arbor, Michigan); Ting Zhao (Ann Arbor, Michigan); Arul Chinnaiyan (Ann Arbor, Michigan); Irfan A. Asangani (Ann Arbor, Michigan); Jeanne Stuckey (Fenton, Michigan); Jennifer Lynn Meagher (Ann Arbor, Michigan); Xu Ran (Ann Arbor, Michigan); Yang Hu (Ann Arbor, Michigan)
ABSTRACT	The present disclosure provides substituted 9H-pyrimido[4,5-b]indoles and 5H-pyrido[4,3-b]indoles and related analogs represented by Formula I: and the pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R^1a, A, B¹, B², G, X¹, Y¹, Y², and Y³are as defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I to treat a condition or disorder responsive to inhibition of BET bromodomains. Compounds of the present disclosure are especially useful for treating cancer.
FILED	Monday, February 27, 2017
APPL NO	15/443336
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/519 (20130101) A61K 31/538 (20130101) A61K 31/5377 (20130101) Heterocyclic Compounds C07D 487/04 (20130101) C07D 487/14 (20130101) C07D 519/00 (20130101) Original (OR) Class
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10253065 — Compositions containing HC-HA/PTX3 complexes and methods of use thereof

US 10253065	Tseng et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	TissueTech, Inc. (Doral, Florida)
ASSIGNEE(S)	TISSUETECH, INC. (Miami, Florida)
INVENTOR(S)	Scheffer Tseng (Pinecrest, Florida); Hua He (Miami, Florida); Sean Tighe (Tampa, Florida); Suzhen Zhang (Miami, Florida); Ying-Tieng Zhu (Homestead, Florida)
ABSTRACT	Provided herein are methods for the production of native and reconstituted hyaluronan (HA) complexes containing pentraxin-3 (PTX3) and heavy chain 1 (HC1) of inter alpha inhibitor (IαI). Compositions containing the complexes and therapeutic methods using the complexes are provided. Combinations and kits for use in practicing the methods also are provided.
FILED	Wednesday, July 20, 2016
APPL NO	15/214706
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/191 (20130101) A61K 47/55 (20170801) A61K 47/69 (20170801) A61K 47/6957 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 2300/41 (20130101) A61L 2300/236 (20130101) A61L 2300/252 (20130101) A61L 2300/412 (20130101) A61L 2300/426 (20130101) Peptides C07K 1/36 (20130101) Original (OR) Class C07K 14/47 (20130101) C07K 14/81 (20130101) C07K 14/525 (20130101) C07K 19/00 (20130101)
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10253069 — Compositions and methods for regulating arterial tone

US 10253069	Gaston et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	Benjamin M. Gaston (Gates Mills, Ohio); Adam C. Straub (Pittsburgh, Pennsylvania); Brant E. Isakson (Charlottesville, Virginia); Linda Columbus (Charlottesville, Virginia)
ABSTRACT	The present invention provides compositions and methods for regulating arterial tone based on the discovery herein of novel expression and regulation of hemoglobin alpha and cytochrome B5 reductase 3 and the effects on NO and NOS.
FILED	Friday, July 07, 2017
APPL NO	15/643633
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Original (OR) Class C07K 14/805 (20130101) C07K 16/00 (20130101) C07K 16/18 (20130101) C07K 2317/76 (20130101) C07K 2319/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2320/30 (20130101)
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10253070 — Immunotherapy targeting of the shared abnormal conformational state of amyloidogenic peptides/proteins

US 10253070	Wisniewski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	New York University (New York, New York)
ASSIGNEE(S)	New York University (New York, New York)
INVENTOR(S)	Thomas M. Wisniewski (Staten Island, New York); Fernando Goni (New York, New York)
ABSTRACT	The present invention is directed to pharmaceutical agents and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
FILED	Monday, December 04, 2017
APPL NO	15/830902
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/10 (20130101) A61K 39/0007 (20130101) A61K 39/3955 (20130101) A61K 2039/55505 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 16/18 (20130101) C07K 2317/34 (20130101) C07K 2319/70 (20130101)
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10253071 — Selectin inhibitors, composition, and uses related thereto

US 10253071	Cummings et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Emory University (Atlanta, Georgia)
ASSIGNEE(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Emory University (Atlanta, Georgia)
INVENTOR(S)	Richard D. Cummings (Atlanta, Georgia); Elliot L. Chaikof (Newton, Massachusetts); Venkata R. Krishnamurthy (Ashland, Massachusetts); Mohammed Sardar (Malden, Massachusetts)
ABSTRACT	This disclosure relates to selectin inhibitors, compositions, and methods related thereto. In certain embodiments, the disclosure relates to glycopeptides that contain one more modified amino acids conjugated to a saccharide or polysaccharide. In certain embodiments, the disclosure relates to uses of the glycopeptides as anti-inflammatory, anti-thrombotic, or anti-metastatic agents.
FILED	Friday, May 23, 2014
APPL NO	14/895606
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/08 (20130101) C07K 9/00 (20130101) Original (OR) Class C07K 14/70564 (20130101)
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10253084 — Methods for predicting three-dimensional structures for alpha helical membrane proteins and their use in design of selective ligands

US 10253084	Abrol et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	Ravinder Abrol (Pasadena, California); William A. Goddard (Pasadena, California); Adam R. Griffith (Pasadena, California); Victor Wai Tak Kam (New York, New York)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Ravinder Abrol (Pasadena, California); William A. Goddard (Pasadena, California); Adam R. Griffith (Pasadena, California); Victor Wai Tak Kam (New York, New York)
ABSTRACT	A method for practical prediction of the three-dimensional structure of α-helical membrane proteins (HMPs) is described. The method allows one to predict the binding site and structure for strongly bound ligands. The method combines a protocol of computational methods enabling a complete ensemble of packings to be sampled and systematically reducing this ensemble to progressively more accurate structures until at the end there remain a few that might be functionally relevant and likely to play a role in all binding and activation processes. This method is well suited to automatic operation making it practical to obtain, for example, the ensemble of important structures for all human GPCRs. With this ensemble of all active GPCR structures in the human body, an infimum method is presented to maximize efficacy toward the selected target while minimizing binding to all other GPCRs to eliminate toxicity arising from cross-reacting with other GPCRs (a most common source of drug failure). This infimum method is broadly applicable to any set of proteins where a ligand is desired to be able to modulate the function of one protein while not affecting the function of other proteins.
FILED	Thursday, June 19, 2008
APPL NO	12/142707
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Peptides C07K 14/705 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/04 (20130101)
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10253089 — Matrix metalloproteinase cleavable protein polymers for cancer gene therapy

US 10253089	Ghandehari et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Hamidreza Ghandehari (Salt Lake City, Utah); Joseph Cappello (Salt Lake City, Utah); Jordan Frandsen (Salt Lake City, Utah); Joshua Gustafson (Seattle, Washington); Khaled Greish (Salt Lake City, Utah); Robert Andrew Price (Salt Lake City, Utah)
ABSTRACT	A delivery system that includes a recombinantly synthesized protein polymer with protease cleavage sites such as matrix metalloproteinase responsive sequences engineered within the protein polymer. The system may be used to treat cancer, wounds, or pathological conditions in other tissues that express excess protease relative to healthy tissue.
FILED	Thursday, May 30, 2013
APPL NO	14/403979
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/522 (20130101) A61K 38/39 (20130101) A61K 38/45 (20130101) A61K 47/42 (20130101) A61K 47/64 (20170801) A61K 47/65 (20170801) A61K 47/66 (20170801) A61K 48/0008 (20130101) A61K 48/0041 (20130101) A61K 48/0083 (20130101) Peptides C07K 14/78 (20130101) Original (OR) Class C07K 14/43586 (20130101) C07K 2319/50 (20130101) C07K 2319/70 (20130101) C07K 2319/95 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10043 (20130101) C12N 2710/10071 (20130101) C12N 2710/10332 (20130101) C12N 2710/10345 (20130101) C12N 2710/16033 (20130101) Enzymes C12Y 207/01021 (20130101)
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10253111 — Methods and compositions relating to anti-Chi3l1 antibody reagents

US 10253111	Elias et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	BROWN UNIVERSITY (Providence, Rhode Island)
ASSIGNEE(S)	Brown University (Providence, Rhode Island)
INVENTOR(S)	Jack A. Elias (Providence, Rhode Island); Chun Geun Lee (Woodbridge, Connecticut); Chuan Hua He (Madison, Connecticut); Bing Ma (Branford, Connecticut); Suchitra Kamle (Providence, Rhode Island); Chang-Min Lee (Warwick, Rhode Island)
ABSTRACT	Described herein are methods and compositions relating to anti-Chi3L1 antibodies, antibody reagents, and antigen-binding fragments thereof which display superior properties, e.g., high sensitivity, high specificity, high binding affinity, neutralization activity ex vivo and in vivo (e.g., blocks Chi3L1-induced MAPK and AKT signaling). Methods of treatment, e.g., of treating cancer, obesity, and/or asthma by administering the compounds described herein are also provided.
FILED	Friday, September 07, 2018
APPL NO	16/124558
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 35/00 (20180101) Peptides C07K 16/18 (20130101) C07K 16/40 (20130101) Original (OR) Class C07K 2317/76 (20130101)
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10253144 — Compositions and methods related to proteins capable of reversible transition to a melt

US 10253144	Demirel et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Melik Demirel (State College, Pennsylvania); Abdon Pena-Francesch (State College, Pennsylvania)
ABSTRACT	Provided are compositions and methods for making a variety of products. The methods involve mixing sucker ring teeth (SRT) protein and a plasticizer or a solvent to obtain a mixture of the SRT protein and the plasticizer. When the SRT is mixed with a plasticizer it is heated to between 32° C. and 195° C. to obtain an SRT protein melt. The melt is used to form a wide variety of products. When the SRT is mixed with a solvent, such as an organic solvent or an aqueous solvent, a solution of the SRT protein is formed, and is subsequently used to forming a product from the solution, wherein the product contains SRT protein.
FILED	Thursday, September 10, 2015
APPL NO	14/850001
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/424 (20130101) B29C 33/3857 (20130101) B29C 41/003 (20130101) B29C 41/12 (20130101) B29C 41/045 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2003/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/18 (20130101) C08J 5/18 (20130101) Original (OR) Class C08J 2389/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0016 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 189/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/00 (20130101) D01F 6/94 (20130101)
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10253287 — In vitro culture model of anisotropic to isotropic transitions

US 10253287	Rivet et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
ASSIGNEE(S)	Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S)	Christopher John Rivet (Grand Blanc, Michigan); Gregory Patrick Desmond (Marshfield, Massachusetts); Jonathan Michael Zuidema (Grand Haven, Michigan); Ryan James Gilbert (Troy, New York)
ABSTRACT	Cell culture devices, and related methods and kits, for modeling isotropic-to-anisotropic cellular transitions are provided. The devices can include a substrate having an isotropic film surface with one or more regions of aligned fibers dispersed thereon.
FILED	Tuesday, August 25, 2015
APPL NO	15/506974
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class C12M 23/20 (20130101) C12M 25/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0622 (20130101)
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10253300 — Adapted rhinovirus C

US 10253300	Bochkov et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Yury A. Bochkov (Fitchburg, Wisconsin); James E. Gern (Madison, Wisconsin); Ann C. Palmenberg (Madison, Wisconsin); Kelly E. Watters (Madison, Wisconsin)
ABSTRACT	A mutated rhinovirus C, methods of creating and methods of propagating thereof, wherein the mutated rhinovirus shows enhanced virus yields after infection and induced visible cytopathic effect.
FILED	Wednesday, August 10, 2016
APPL NO	15/232913
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2770/32721 (20130101) C12N 2770/32722 (20130101)
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10253314 — Ligand-guided-selection method for screening antigen-specific ligands

US 10253314	Mallikaratchy
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Research Foundation of the City University of New York (New York, New York)
ASSIGNEE(S)	Research Foundation of the City University of New York (New York, New York)
INVENTOR(S)	Prabodhika Mallikaratchy (New York, New York)
ABSTRACT	A Ligand-guided-Selection (LIGS) method for identifying highly specific aptamers against a predetermined antigen of a target is provided. LIGS uses a stronger and highly specific bivalent binder (e.g. an antibody) interacting with its cognate antigen to displace specific aptamers from a partially enriched SELEX pool. Elution of the displaced aptamers provides aptamers that are specific to the predetermined antigen.
FILED	Wednesday, April 13, 2016
APPL NO	15/097845
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1048 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101)
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10253318 — Methods and compositions for the treatment of cancer or other diseases

US 10253318	Yu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	City of Hope (Duarte, California)
ASSIGNEE(S)	CITY OF HOPE (Duarte, California)
INVENTOR(S)	Hua Yu (Glendora, California); Marcin Kortylewski (Monrovia, California); Richard Jove (Pasadena, California); Piotr Marek Swiderski (San Dimas, California); John J. Rossi (Azusa, California)
ABSTRACT	The present invention relates to methods and compositions for the treatment of diseases, including cancer, infectious diseases and autoimmune diseases. The present invention also relates to methods and compositions for improving immune function. More particularly, the present invention relates to multifunctional molecules that are capable of being delivered to cells of interest for the treatment of diseases and for the improvement in immune function.
FILED	Wednesday, June 14, 2017
APPL NO	15/623187
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 47/55 (20170801) A61K 47/61 (20170801) A61K 47/64 (20170801) A61K 47/549 (20170801) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/1135 (20130101)
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10253353 — Enhanced methods of ribonucleic acid hybridization

US 10253353	Bhattacharyya et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S)	The Broad Institute, Inc. (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Roby Bhattacharyya (Cambridge, Massachusetts); Deborah Hung (Cambridge, Massachusetts); Milesh Patel (Jersey City, New Jersey)
ABSTRACT	This disclosure relates to a method for increasing the hybridization efficiency of a probe and a target RNA in a sample, for example to identify a particular RNA present in the sample. The method includes heating a lysate sample comprising at least one target RNA, such as a tRNA, mRNA or rRNA, at a temperature of about 95° C. for a time sufficient to interfere with secondary structure of the RNA, wherein the time is short enough, such that the RNA in the cell lysate sample are not significantly degraded, and wherein the lysate comprises a cell lysis buffer comprising a chemical denaturant. To detect a target RNA in the lysate, the lysate is contacted with at least one detectable probe, such as a labeled probe, designed to specifically hybridize to the target RNA in the lysate.
FILED	Friday, December 05, 2014
APPL NO	15/101676
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6832 (20130101) Original (OR) Class C12Q 1/6832 (20130101) C12Q 2523/113 (20130101) C12Q 2527/101 (20130101) C12Q 2527/113 (20130101)
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10253357 — Colorimetric detection of nucleic acid amplification

US 10253357	Mitra et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Diassess Inc. (Emeryville, California)
ASSIGNEE(S)	DIASSESS INC. (Emeryville, California)
INVENTOR(S)	Debkishore Mitra (Berkeley, California); Ivan Krastev Dimov (Union City, California); John Robert Waldeisen (Berkeley, California)
ABSTRACT	Colorimetry is used to detect amplification reaction products. A sample is contacted with a reaction mix under conditions such that an amplification reaction occurs and produces an amplification reaction product if the sample contains a target nucleic acid template molecule. The reaction mix includes an enzyme for catalyzing the amplification reaction, and at least one halochromic agent. If the target nucleic acid template molecule is present, the amplification reaction changes the starting pH of the reaction mix to cause a detectable colorimetric change of the halochromic agent, thereby indicating the presence of the target nucleic acid. If the target nucleic acid template molecule is not present, the amplification reaction does not generate an adequate number of protons to sufficiently change the starting pH of the reaction mix to cause a detectable colorimetric change of the halochromic agent, thereby indicating that the amplification reaction product has not been produced.
FILED	Friday, April 24, 2015
APPL NO	15/306240
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) Original (OR) Class C12Q 1/6846 (20130101) C12Q 1/6846 (20130101) C12Q 2527/119 (20130101) C12Q 2527/125 (20130101) C12Q 2563/173 (20130101)
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10253367 — Biomarkers for locally advanced breast cancer (LABC) and inflammatory breast cancer (IBC)

US 10253367	Reihani et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Duke University (Durham, North Carolina)
ASSIGNEE(S)	DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S)	Sharareh Reihani (Chapel Hill, North Carolina); Mark Dewhirst (Chapel Hill, North Carolina); Kouros Owzar (Chapel Hill, North Carolina); Oana Craciunescu (Hillsborough, North Carolina)
ABSTRACT	The present disclosure provides methods and kits for using biomarkers for predicting treatment response, determining likely survival rate, and/or determining aggressiveness of conditions such as Locally Advanced Breast Cancer (LABC) and Inflammatory Breast Cancer (IBC) in a subject.
FILED	Monday, February 10, 2014
APPL NO	14/176999
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class
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10253368 — Molecular signatures of ovarian cancer

US 10253368	Orsulic et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S)	Cedars-Sinai Medical Center (Los Angeles, California)
ASSIGNEE(S)	Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S)	Sandra Orsulic (Los Angeles, California); Beth Y. Karlan (Los Angeles, California); Xiaojiang Cui (Arcadia, California); Mourad Tighiouart (Beverly Hills, California); Dong-Joo Cheon (Los Angeles, California); Zhenqiu Liu (Sherman Oaks, California)
ABSTRACT	Described herein are gene signatures providing prognostic, diagnostic, treatment and molecular subtype classifications of ovarian cancers through generation of ovarian cancer disease signatures (OCDSs) that account for molecular heterogeneity present in gynecological cancers. An ovarian cancer fixed signature (OCFS) is described which relates to the core programming of disease development, in addition to an ovarian cancer stem cell (OCSC) signature. Development various disease signature, suggests personalized treatment strategies focused on molecular subtypes of gynecological cancers, such as triage tests for patients.
FILED	Friday, April 17, 2015
APPL NO	14/690291
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57449 (20130101)
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10254271 — Controlling translocation through nanopores with fluid walls

US 10254271	Mayer et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Michael Mayer (Ann Arbor, Michigan); Erik Yusko (Ann Arbor, Michigan); Jerry Yang (La Jolla, California)
ABSTRACT	Improved resolution and detection of nanoparticles are achieved when a nanopore connecting liquid compartments in a device running on the Coulter principle is provided with fluid coatings such as lipid walls. Fluid lipid walls are made of a lipid bilayer, and preferably include lipid anchored mobile ligands as part of the lipid bilayer. By varying the nature and concentration of the mobile ligand in the lipid bilayer, multifunctional coatings of lipids are provided.
FILED	Wednesday, May 18, 2016
APPL NO	15/157591
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2563/131 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1209 (20130101) G01N 33/48721 (20130101) Original (OR) Class G01N 2015/0038 (20130101)
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10254285 — Methods for detecting and treating cancer metastasis

US 10254285	Di Vizio et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Cedars-Sinai Medical Center (Los Angeles, California)
ASSIGNEE(S)	Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S)	Dolores Di Vizio (Los Angeles, California); Michael R. Freeman (Los Angeles, California); Matteo Morello (Beverly Hills, California); Valentina R. Minciacchi (Los Angeles, California)
ABSTRACT	The invention provides methods for isolating large oncosomes and determining cancer metastasis based on the presence of large oncosomes and contents of the large oncosomes in a subject in need thereof. Also provided herein are methods for treating cancer metastasis by specifically targeting contents of the large oncosomes.
FILED	Wednesday, October 14, 2015
APPL NO	14/883421
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) Original (OR) Class G01N 2800/56 (20130101)
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10254290 — Systems and methods for identifying protein stabilizers

US 10254290	Fisher et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The University of Kansas (Lawrence, Kansas)
ASSIGNEE(S)	The University of Kansas (Lawrence, Kansas)
INVENTOR(S)	Mark T. Fisher (Prairie Village, Kansas); Subhashchandra Naik (Kansas City, Kansas)
ABSTRACT	A device for studying protein conformation transformation can include a macroscopic substrate, and chaperonin proteins bound to the substrate, each chaperonin protein being capable of binding to a protein of interest during or after undergoing protein conformation transformation. The device may also include the proteins of interest bound to the substrate, where the substrate is included in a label-free assay system. A method of studying protein conformation transformation can include: providing a macroscopic substrate bound with the chaperonin protein and immersing the chaperonin protein in a study composition having the protein of interest, or include providing a macroscopic substrate bound with the protein of interest; and immersing the protein in a study composition having the chaperonin. Such a method can be done with and without a potential stabilizer in order to determine whether the potential stabilizer stabilizes the protein of interest.
FILED	Monday, March 06, 2017
APPL NO	15/450716
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/32 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) G01N 33/6845 (20130101) Original (OR) Class G01N 33/54373 (20130101) G01N 2333/954 (20130101) G01N 2333/90666 (20130101) G01N 2500/00 (20130101) G01N 2500/04 (20130101) G01N 2500/20 (20130101)
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10254291 — Quaternary ammonium containing isobaric tag for quantitative glycan profiling

US 10254291	Li et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S)	UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Shuwei Li (Clarksburg, Maryland); Hui Zhang (Ellicott City, Maryland); Shuang Yang (Ellicott City, Maryland)
ABSTRACT	The disclosure provides quaternary ammonium containing isobaric tag reagents useful in the analysis of biomolecules and methods of making and using the quaternary ammonium containing isobaric tag reagents. The quaternary ammonium containing isobaric tag reagents are particularly useful for glycan analysis, especially quantitative glycan profiling such as glycan quantitation by tandem mass spectrometry.
FILED	Monday, October 12, 2015
APPL NO	14/880972
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) Original (OR) Class G01N 2458/15 (20130101) G01N 2560/00 (20130101)
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10254368 — Magnetic resonance imaging that nulls signals from two or more tissues to better delineate an interested tissue

US 10254368	Basha et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	BETH ISRAEL DEACONESS MEDICAL CENTER (Boston, Massachusetts)
ASSIGNEE(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S)	Tamer Basha (Revere, Massachusetts); Reza Nezafat (Waban, Massachusetts)
ABSTRACT	A system and method for acquiring magnetic resonance imaging (MRI) images with an MRI system is provided. The system and method directs the MRI system first to produce an inversion recovery radio frequency (RF) pulse, wait for a time period, produce a T2-preparation RF pulse, wait for another time period, and then acquire data of a part of a subject. The first produced RF pulse rotates net magnetization 180 degrees about an axis. The pulse sequence used to acquire data can be any two-dimensional or three-dimensional sequence used to acquire a volume in the subject. The two waiting time periods are chosen such that the signals of two or more tissues of the subject are nulled.
FILED	Tuesday, February 02, 2016
APPL NO	15/548691
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 2576/023 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/483 (20130101) G01R 33/5602 (20130101) Original (OR) Class
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10254369 — Pipeline engine for specifying, visualizing, and analyzing MRI image reconstructions

US 10254369	Overall et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	HEARTVISTA, INC. (Menlo Park, California)
ASSIGNEE(S)	HeartVista, Inc. (Menlo Park, California)
INVENTOR(S)	William Overall (Menlo Park, California); Juan Santos (Palo Alto, California)
ABSTRACT	Systems and methods are provided for the imaging of a subject (e.g., patient). A pipeline architecture is presented that facilitates the development of high-quality, application-specific data reconstructions. A plurality of processing nodes is provided, each node comprising one or more processing tasks for data transformation. Two or more processing nodes are linked together to form a functional pipeline, each pipeline configured to generate image data from a raw image data set, such as raw magnetic resonance imaging data. The generated image data is used to generate the image of the subject. The processing nodes and the functional pipeline can be dynamically reconfigured to optimize the computing resources used. The processing nodes and the pipeline may be visualized and queried to facilitate debugging and the configuration of an image processing procedure.
FILED	Wednesday, October 28, 2015
APPL NO	14/924864
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/546 (20130101) G01R 33/5608 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 1/20 (20130101) G06T 11/206 (20130101) G06T 2200/24 (20130101)
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10256262 — System and method for Hilbert phase imaging

US 10256262	Popescu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Hamamatsu Photonics K.K. (Hamamatsu, Japan)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Hamamatsu Photonics K.K. (Hamamatsu, Japan)
INVENTOR(S)	Gabriel Popescu (Champaign, Illinois); Ramachandra Dasari (Shererville, Indiana); Michael Feld (Jamaica Plain, Massachusetts); Takahiro Ikeda (Hamamatsu, Japan)
ABSTRACT	Hilbert phase microscopy (HPM) as an optical technique for measuring high transverse resolution quantitative phase images associated with optically transparent objects. Due to its single-shot nature, HPM is suitable for investigating rapid phenomena that take place in transparent structures such as biological cells. A preferred embodiment is used for measuring biological systems including measurements on red blood cells, while its ability to quantify dynamic processes on the millisecond scale, for example, can be illustrated with measurements on evaporating micron-size water droplets.
FILED	Tuesday, June 10, 2014
APPL NO	14/301187
ART UNIT	2878 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 15/1475 (20130101) G01N 21/453 (20130101) G01N 33/49 (20130101) G01N 2015/008 (20130101) G01N 2015/0073 (20130101) G01N 2015/145 (20130101) G01N 2015/1454 (20130101) G01N 2015/1497 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00134 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14601 (20130101) Original (OR) Class
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10257100 — Enabling resilient microgrid through ultra-fast programmable network

US 10257100	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	University of Connecticut (Farmington, Connecticut)
ASSIGNEE(S)	University of Conneticut (Farmington, Connecticut)
INVENTOR(S)	Peng Zhang (Storrs Mansfield, Connecticut); Bing Wang (Storrs Mansfield, Connecticut); Peter B. Luh (Storrs Mansfield, Connecticut); Lingyu Ren (Storrs Mansfield, Connecticut); Yanyuan Qin (Storrs Mansfield, Connecticut)
ABSTRACT	Systems and methods for integrating ultra-fast programmable networks in microgrid are disclosed to provide flexible and easy-to-manage communication solutions, thus enabling resilient microgrid operations in face of various cyber and physical disturbances. The system is configured to establish a novel software-defined networking (SDN) based communication architecture which abstracts the network infrastructure from the upper-level applications to significantly expedite the development of microgrid applications, develop three functions of the SDN controller for microgrid emergency operations, including time delay guarantee, failover reconfiguration and rate limit and create a hardware-in-the-loop cyber-physical platform for evaluating and validating the performance of the presented architecture and control techniques.
FILED	Friday, April 28, 2017
APPL NO	15/581601
ART UNIT	2461 — Multiplex and VoIP
CURRENT CPC	Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 13/0086 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/08 (20130101) H04L 45/28 (20130101) H04L 45/42 (20130101) H04L 45/64 (20130101) H04L 45/121 (20130101) H04L 47/24 (20130101) H04L 47/25 (20130101) Original (OR) Class H04L 47/41 (20130101)
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Department of Defense (DOD)

10251841 — Polymeric depots for localization of agent to biological sites

US 10251841	Grinstaff et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
ASSIGNEE(S)	TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
INVENTOR(S)	Mark W. Grinstaff (Brookline, Massachusetts); Aaron H. Colby (Concord, Massachusetts); Yolonda Colson (Dover, Massachusetts)
ABSTRACT	Provided herein are polymeric particles and compounds and processes that can be used to prepare polymer-based particles and methods of using those particles to localize or concentrate a subsequently delivered agent to an in vivo site.
FILED	Wednesday, October 17, 2012
APPL NO	14/351972
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1641 (20130101) Original (OR) Class A61K 9/5138 (20130101) A61K 31/337 (20130101) A61K 31/352 (20130101) A61K 31/519 (20130101) A61K 47/555 (20170801) A61K 49/0054 (20130101)
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10252094 — Fire extinguisher manifold with safety interlock cross-bolt

US 10252094	Gorenc
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America as Represented by the Secretary of the United States Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Louis J. Gorenc (Westland, Michigan)
ABSTRACT	A fire extinguisher system that generally provides a passive ability to prevent at least some inadvertent discharge events. The fire extinguisher system having a passively activated (turned on) and deactivated (turned off) sliding safety interlock cross shaft structure. The system interlock operation is generally performed without an operator performing any new or additional tasks in addition to those tasks that are typically implemented during installation, repair, and/or maintenance tasks. The safety interlock shaft is generally shaped and positioned to prevent inadvertent discharge of fire extinguishing chemicals via propellant when the outlet does not have either of a discharge conduit (pipe, tubing, or the like) or the anti-recoil plug properly installed therein.
FILED	Friday, October 14, 2016
APPL NO	15/293897
ART UNIT	3753 — Fluid Handling and Dispensing
CURRENT CPC	Fire-fighting A62C 35/023 (20130101) A62C 35/68 (20130101) Original (OR) Class Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 35/00 (20130101)
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10252264 — Sample preparation module with stepwise pressurization mechanism

US 10252264	Shen et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	SLIPCHIP CORPORATION (Chicago, Illinois)
ASSIGNEE(S)	Talis Biomedical Corporation (Menlo Park, California)
INVENTOR(S)	Feng Shen (San Jose, California); Chris Da Costa (Vista, California); Hedia Maamar (San Jose, California)
ABSTRACT	The present invention relates to fluidic systems for controlling one or more fluids or reagents. These systems can be used in combination with one or more devices for assaying, processing, or storing samples. In particular, the systems and related methods can allow for controlled pressure and actuation of fluids.
FILED	Thursday, February 05, 2015
APPL NO	15/117156
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 2200/0621 (20130101) B01L 2200/0631 (20130101) B01L 2300/021 (20130101) B01L 2300/023 (20130101) B01L 2300/027 (20130101) B01L 2300/087 (20130101) B01L 2300/0663 (20130101) B01L 2300/0681 (20130101) B01L 2300/0832 (20130101) B01L 2400/0475 (20130101) B01L 2400/0478 (20130101) B01L 2400/0487 (20130101) B01L 2400/0644 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) G01N 2035/00881 (20130101)
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10252328 — Ceramic and refractory metal core assembly

US 10252328	Propheter-Hinckley
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Tracy A. Propheter-Hinckley (Manchester, Connecticut)
ABSTRACT	A core assembly for forming a cast component includes a refractory metal core and a ceramic core element. The refractory metal core includes first and second ends and sides extending from the first end to the second end. The ceramic core element includes a slot positioned between first and second lands, each land having an inner surface facing the slot and an adjacent outer surface. The first end of the refractory metal core is secured within the slot with an adhesive, and the refractory metal core extends from the ceramic core element in both a longitudinal and a transverse direction. The slot, lands, and refractory metal core form a core assembly providing access paths to the sides of the refractory metal core. Surplus adhesive is removed from the refractory metal core via the access paths. Investment casting provides the component with an internal passage and an internal cooling circuit.
FILED	Wednesday, October 12, 2016
APPL NO	15/291720
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Foundry Moulding B22C 7/02 (20130101) B22C 9/04 (20130101) B22C 9/24 (20130101) B22C 9/103 (20130101) B22C 9/108 (20130101) Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 23/00 (20130101) B22D 25/02 (20130101) Original (OR) Class Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) F01D 5/186 (20130101) F01D 9/02 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/21 (20130101) F05D 2230/211 (20130101) F05D 2300/13 (20130101)
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10252456 — Method of making actuators based on unbalanced moments of inertia

US 10252456	Fossey et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Stephen A. Fossey (Framingham, Massachusetts); Barry S. DeCristofano (Plympton, Massachusetts)
ABSTRACT	Methods and computer-readable mediums are provide that, in some embodiments maximize bending of an actuator and, in other embodiments, minimize bending of the actuator. For example, in one embodiment, a method is provided that designs and determines a Ratio1 for a first component. Ratio1 is a modulus of inertia for the first component divided by a Young's Modulus for the first component. Thereafter, a second component is designed that has a Ratio2 substantially equal to the Ratio1 of the first component. Ratio2 is a modulus of inertia for the second component divided by a Young's Modulus for the second component. Thereafter, the first component and the second component can be used to make an actuator that is spun into fiber to make products (e.g., batting material, woven material, a suture, a thermostat needle, a gel, etc.). Other embodiments are provided that utilize computer-readable medium.
FILED	Thursday, September 03, 2015
APPL NO	14/844034
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/06 (20130101) Original (OR) Class B29C 47/0038 (20130101) B29C 65/48 (20130101) B29C 65/72 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/12 (20130101) B29K 2995/0012 (20130101) B29K 2995/0041 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2009/00 (20130101) B29L 2031/731 (20130101) Woven Fabrics; Methods of Weaving; Looms D03D 15/0027 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) G06F 17/50 (20130101)
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10252466 — Systems and methods of machine vision assisted additive fabrication

US 10252466	Ramos et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Javier E. Ramos (San Juan, Puerto Rico); Pitchaya Sitthi-Amorn (Cambridge, Massachusetts); Wojciech Matusik (Lexington, Massachusetts); Yuwang Wang (Beijing, China PRC)
ABSTRACT	The present application relates generally to systems and methods for using machine vision to provide information on one or more aspects of an additive fabrication device, such as calibration parameters and/or an object formed by the device or in the process of being formed by the device. According to some aspects, a method is provided for calibrating an additive fabrication device. According to some aspects, a method is provided for assessing at least a portion of an object formed using an additive fabrication device. According to some aspects, a method is provided for fabricating a second object in contact with a first object using an additive fabrication device. According to some aspects, an additive fabrication device configured to perform one or more of the above methods may be provided.
FILED	Thursday, March 12, 2015
APPL NO	14/645616
ART UNIT	1747 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) B29C 64/112 (20170801) B29C 64/386 (20170801) Original (OR) Class B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201)
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10252954 — Multi-layered stable propellant composition

US 10252954	Park et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Dongkyun Park (Dover, New Jersey); Joseph Laquidara (Westwood, New Jersey); Viral Panchal (Parlin, New Jersey); Ryan Ordemann (Verona, New Jersey); Carlton Adam (Newton, New Jersey); Robin Crownover (Rockaway, New Jersey)
ABSTRACT	The present invention is directed to propellant grains having multiple layers consisting of an outer, slow burning, layer composition and an inner, fast burning, layer with desirable progressivity burn rates. The outer, slow burning, layer comprising a first energetic material, a first plasticizer and a first binder and an inner, fast burning, layer comprising a second energetic material, and the same plasticizer as the outer layer, and a second binder. The compositions in the propellant grain provided herein provides for a burn rate energy differential between the outer, slow burning, layer and inner, fast burning, layer of at least 2.
FILED	Wednesday, May 10, 2017
APPL NO	15/591159
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 45/12 (20130101) Original (OR) Class
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10252966 — Renewable polyphenols, thermoplastics, and resins

US 10252966	Harvey et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Benjamin G. Harvey (Ridgecrest, California); Heather A. Meylemans (Ridgecrest, California)
ABSTRACT	A series of renewable bisphenols has been synthesized from creosol (2-methoxy-4-methylphenol) through stoichiometric condensation with short chain aldehydes. Creosol can be readily produced from lignin, potentially allowing for the large scale synthesis of bisphenol A replacements from abundant waste biomass. The renewable bisphenols were isolated in good yield and purity without resorting to solvent intense purification methods. Zinc acetate was shown to be selective catalyst for ortho-coupling of formaldehyde but was unreactive with more sterically demanding aldehydes. Dilute HCl and HBr solutions were shown to be effective catalysts for the selective coupling of aldehydes in the position meta to the phenol. Acid solutions could be recycled and used multiple times without decreases in activity or yield.
FILED	Thursday, April 11, 2013
APPL NO	13/860975
ART UNIT	1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 41/18 (20130101) C07C 41/30 (20130101) Original (OR) Class C07C 43/23 (20130101) C07C 43/2055 (20130101) C07C 261/02 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 64/1608 (20130101) C08G 73/0644 (20130101) C08G 73/0655 (20130101)
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10253050 — Fluorinated cycloalkene functionalized silicas

US 10253050	Iacono et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as requested by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Scott Iacono (Colorado Springs, Colorado); Abby Rose Jennings (Colorado Springs, Colorado)
ABSTRACT	Fluorinated cyclopentene moieties and fluorinated cyclopentene functionalized silica materials are provided. The fluorinated cyclopentene functionalized silica materials include a silica material having the fluorinated cyclopentene moiety covalently bonded thereto. Exemplary silica materials include a polysilsesquioxane, a nanosilica, a microsilica, a silica gel, a silica aerogel, or combinations thereof. The fluorinated cyclopentene moieties are based on a modification of perfluorocyclopentene (i.e., 1,2,3,3,4,4,5,5-octafluoro-1-cyclopentene) by nucleophilic substitution with an appropriate nucleophile having a reactive functional group. Methods for preparing fluorinated cyclopentene moieties and the corresponding fluorinated cyclopentene functionalized silica materials are also provided.
FILED	Friday, May 05, 2017
APPL NO	15/587819
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 43/192 (20130101) C07C 43/247 (20130101) C07C 323/17 (20130101) C07C 2601/10 (20170501) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/12 (20130101) C07F 7/21 (20130101) Original (OR) Class C07F 7/1804 (20130101)
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10253144 — Compositions and methods related to proteins capable of reversible transition to a melt

US 10253144	Demirel et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Melik Demirel (State College, Pennsylvania); Abdon Pena-Francesch (State College, Pennsylvania)
ABSTRACT	Provided are compositions and methods for making a variety of products. The methods involve mixing sucker ring teeth (SRT) protein and a plasticizer or a solvent to obtain a mixture of the SRT protein and the plasticizer. When the SRT is mixed with a plasticizer it is heated to between 32° C. and 195° C. to obtain an SRT protein melt. The melt is used to form a wide variety of products. When the SRT is mixed with a solvent, such as an organic solvent or an aqueous solvent, a solution of the SRT protein is formed, and is subsequently used to forming a product from the solution, wherein the product contains SRT protein.
FILED	Thursday, September 10, 2015
APPL NO	14/850001
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/424 (20130101) B29C 33/3857 (20130101) B29C 41/003 (20130101) B29C 41/12 (20130101) B29C 41/045 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2003/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/18 (20130101) C08J 5/18 (20130101) Original (OR) Class C08J 2389/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0016 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 189/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/00 (20130101) D01F 6/94 (20130101)
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10253261 — Stimuli-responsive liquid crystalline networks

US 10253261	Li et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee); Washington State University (Pullman, Washington)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee); WASHINGTON STATE UNIVERSITY (Pullman, Washington)
INVENTOR(S)	Yuzhan Li (Pullman, Washington); Orlando Rios (Knoxville, Tennessee); Michael Richard Kessler (Pullman, Washington)
ABSTRACT	Liquid crystalline network compositions comprising azo-containing aromatic epoxy units cross-linked with alkylene diacid units having alkylene segments containing at least one methylene unit, wherein the azo-containing aromatic epoxy units and alkylene diacid units are connected by ester linkages resulting from ring-opening esterification between the epoxy units and alkylene diacids, and wherein the azo-containing aromatic epoxy units and alkylene diacid units are in a molar ratio that results in the liquid crystalline network composition exhibiting a glass transition temperature (T_g) of at least 25° C. Methods for producing these compositions and their use in light- or thermal-activated physical deformation, shape memory applications, and self-healing, as well as their ability to be recycled and used in additive manufacturing processes are also described.
FILED	Thursday, January 19, 2017
APPL NO	15/409717
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/28 (20130101) C08G 59/686 (20130101) C08G 59/4207 (20130101) C08G 2280/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/3814 (20130101) Original (OR) Class
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10253336 — High density fuels based on longifolene

US 10253336	Harvey
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Benjamin G Harvey (Ridgecrest, California)
ABSTRACT	A process for making high density fuels having the potential to increase the range and/or loiter time of Navy platforms. Derivation of these fuels from a sustainable source will decrease the carbon footprint of the Department of Defense (DoD) and reduce reliance on nonsustainable petroleum sources. Fuels based on longifolene have volumetric net heats of combustion up to 17% higher than conventional Navy jet fuel (JP-5). Moreover, longifolene can be generated from sustainable biomass sugars via fermentation.
FILED	Wednesday, October 21, 2015
APPL NO	14/919570
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 5/03 (20130101) C07C 5/27 (20130101) C07C 2523/42 (20130101) C07C 2531/025 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) C10L 1/08 (20130101) C10L 2200/0469 (20130101) C10L 2270/04 (20130101) C10L 2270/026 (20130101) C10L 2290/26 (20130101) C10L 2290/543 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/005 (20130101) Original (OR) Class
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10253368 — Molecular signatures of ovarian cancer

US 10253368	Orsulic et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S)	Cedars-Sinai Medical Center (Los Angeles, California)
ASSIGNEE(S)	Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S)	Sandra Orsulic (Los Angeles, California); Beth Y. Karlan (Los Angeles, California); Xiaojiang Cui (Arcadia, California); Mourad Tighiouart (Beverly Hills, California); Dong-Joo Cheon (Los Angeles, California); Zhenqiu Liu (Sherman Oaks, California)
ABSTRACT	Described herein are gene signatures providing prognostic, diagnostic, treatment and molecular subtype classifications of ovarian cancers through generation of ovarian cancer disease signatures (OCDSs) that account for molecular heterogeneity present in gynecological cancers. An ovarian cancer fixed signature (OCFS) is described which relates to the core programming of disease development, in addition to an ovarian cancer stem cell (OCSC) signature. Development various disease signature, suggests personalized treatment strategies focused on molecular subtypes of gynecological cancers, such as triage tests for patients.
FILED	Friday, April 17, 2015
APPL NO	14/690291
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57449 (20130101)
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10253424 — Porous particles and methods of making thereof

US 10253424	Ferrari et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Board of Regents of the University of Texas System (Austin, Texas); The Ohio State University Research Foundation (Columbus, Ohio)
ASSIGNEE(S)	BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (Columbus, Ohio)
INVENTOR(S)	Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugar Land, Texas); Ming-Cheng Cheng (Pearland, Texas)
ABSTRACT	Provided is a particle that includes a first porous region and a second porous region that differs from the first porous region. Also provided is a particle that has a wet etched porous region and that does have a nucleation layer associated with wet etching. Methods of making porous particles are also provided.
FILED	Tuesday, November 11, 2014
APPL NO	14/538065
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 8/25 (20130101) A61K 9/141 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/02 (20130101) C01B 33/021 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/16 (20130101) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/12 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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10253451 — Dual hierarchical omniphobic and superomniphobic coatings

US 10253451	Truong
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Quoc Truong (Hyde Park, Massachusetts)
ABSTRACT	The disclosed subject matter relates to an omniphobic material, including a substrate layer, a first layer of first nanoparticles, the first nanoparticles having a first size and including a particle core and a coating of a fluorodecyl POSS and fluoro-elastomer co-polymer and a second layer of second nanoparticles, the second nanoparticles having a second size and including a particle core and a coating of a fluorodecyl POSS and fluoro-elastomer co-polymer. The first layer of first nanoparticles contact the fabric layer and the second layer of second nanoparticles contact the layer of first nanoparticles. The second size of the second nanoparticles is larger than the first size of the second nanoparticles.
FILED	Thursday, December 07, 2017
APPL NO	15/834234
ART UNIT	1783 — Miscellaneous Articles, Stock Material
CURRENT CPC	Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/00 (20130101) C09D 7/67 (20180101) C09D 7/68 (20180101) C09D 127/12 (20130101) C09D 183/08 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 15/256 (20130101) D06M 15/657 (20130101) Original (OR) Class D06M 23/08 (20130101) D06M 2101/32 (20130101) D06M 2200/10 (20130101) D06M 2200/12 (20130101)
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10253632 — Compressor rim thermal management

US 10253632	Lyons
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Christopher B. Lyons (West Hartford, Connecticut)
ABSTRACT	A flow system for use in a gas turbine engine includes a diffuser case strut defining a first opening at a first radial end, a second opening at a second radial end, and a strut passage radially therethrough between the first and second openings. A first chamber wall and a second chamber wall define a first mixing chamber disposed radially inward of the diffuser case strut in fluid communication with the strut passage. A third chamber wall extends between the second flowpath wall and the second chamber wall to define a second mixing chamber disposed between the diffuser case strut and the first mixing chamber. The second flowpath wall and the second chamber wall are shaped to form a venturi in the second mixing chamber.
FILED	Thursday, December 18, 2014
APPL NO	15/104061
ART UNIT	3748 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/081 (20130101) Original (OR) Class F01D 9/065 (20130101) F01D 25/24 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 7/185 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/213 (20130101) F05D 2260/601 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101)
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10253642 — Gas turbine engine with disk having periphery with protrusions

US 10253642	Hough et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Matthew Andrew Hough (West Hartford, Connecticut); Jeffrey S. Beattie (South Glastonbury, Connecticut)
ABSTRACT	A gas turbine engine includes a turbine section that has a disk rotatable about an axis. The disk has circumferentially-spaced blade mounting features and radially outer rim surfaces extending circumferentially between the blade mounting features. Turbine blades are mounted circumferentially around the disk in the blade mounting features. Seals are arranged radially outwards of the disk adjacent the radially outer rim surfaces such that there are respective passages between the seals and the radially outer rim surfaces. The radially outer rim surfaces include radially-extending protrusions that extend into the respective passages.
FILED	Thursday, August 21, 2014
APPL NO	15/021944
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/081 (20130101) F01D 5/3015 (20130101) F01D 11/02 (20130101) F01D 11/003 (20130101) F01D 11/005 (20130101) F01D 11/006 (20130101) Original (OR) Class F01D 11/008 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/55 (20130101) F05D 2240/127 (20130101) F05D 2260/20 (20130101) F05D 2260/2212 (20130101)
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10253644 — Gas turbine engine clearance control

US 10253644	LeBlanc et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Ryan Edward LeBlanc (Glastonbury, Connecticut); Jordan T. Wall (Hartford, Connecticut); Matthew E. Bintz (West Hartford, Connecticut)
ABSTRACT	A gas turbine engine includes first and second structures secured to one another at a bolted flange joint. A seal is supported by a third structure. A cover is arranged over the bolted flange joint and discrete from the first and second structures. The cover provides a seal land that engages the piston seal and protects the first structure from the adverse thermal environment.
FILED	Tuesday, November 10, 2015
APPL NO	14/937397
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 11/005 (20130101) F01D 11/08 (20130101) Original (OR) Class F01D 11/18 (20130101) F01D 25/145 (20130101) F01D 25/243 (20130101) F01D 25/246 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/00 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/12 (20130101) F05D 2240/15 (20130101) F05D 2240/58 (20130101) F05D 2240/80 (20130101) F05D 2260/231 (20130101)
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10253836 — Three dimensional lattice weaves with tailored damping properties

US 10253836	Guest et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	James K. Guest (Lutherville, Maryland); Kevin J. Hemker (Reisterstown, Maryland); Timothy P. Weihs (Baltimore, Maryland); Stephen M. Ryan (Towson, Maryland); Stefan Szyniszewski (Surrey, United Kingdom)
ABSTRACT	The present invention is directed to three dimensional weaves composed of wires or yarns that offer the potential for damping not achievable with solid materials, including high temperature damping. Three damping mechanisms have been identified: (1) Internal material damping, (2) Frictional energy dissipation (Coulomb damping), and (3) inertial damping (tuned mass damping). These three damping mechanisms can be optimized by modifying the wire material chemistries (metals, ceramics, polymers, etc.), wire sizes, wire shapes, wire coatings, wire bonding, and wire architecture (by removing certain wires). These have the effect of modifying the lattice and wire stiffnesses, masses, coefficients of friction, and internal material damping. Different materials can be used at different locations in the woven lattice. These design variables can also be modified to tailor mechanical stiffness and strength of the lattice, in addition to damping.
FILED	Friday, April 01, 2016
APPL NO	15/088979
ART UNIT	3657 — Material and Article Handling
CURRENT CPC	Woven Fabrics; Methods of Weaving; Looms D03D 25/005 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/08 (20130101) D10B 2101/20 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 1/37 (20130101) F16F 7/00 (20130101) Original (OR) Class F16F 7/08 (20130101) F16F 7/1028 (20130101) F16F 2222/02 (20130101) F16F 2224/02 (20130101) F16F 2224/0208 (20130101) F16F 2224/0275 (20130101) F16F 2224/0291 (20130101) F16F 2226/04 (20130101) F16F 2234/06 (20130101)
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10254169 — Optical detector based on an antireflective structured dielectric surface and a metal absorber

US 10254169	Poutous et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Research Laboratory (NRL)
APPLICANT(S)	The University Of North Carolina At Charlotte (Charlotte, North Carolina)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia); The University of North Carolina at Charlotte (Charlotte, North Carolina)
INVENTOR(S)	Menelaos K. Poutous (Charlotte, North Carolina); Ishwar D. Aggarwal (Charlotte, North Carolina); Jasbinder S. Sanghera (Charlotte, North Carolina); Lynda E. Busse (Charlotte, North Carolina); Brandon L. Shaw (Woodbridge, Virginia)
ABSTRACT	The present invention provides an optical detector device, including: a metal absorber layer; and a dielectric cover layer coupled to the metal absorber layer, wherein the dielectric cover layer includes one or more antireflective structured surfaces. The optical detector device further includes one or more of a passive substrate layer and an active thermoelectric element layer coupled to the metal absorber layer opposite the dielectric cover layer. The one or more antireflective structured surfaces each utilize a random pattern.
FILED	Thursday, August 06, 2015
APPL NO	15/508951
ART UNIT	2884 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/10 (20130101) G01J 5/12 (20130101) G01J 5/34 (20130101) G01J 5/0803 (20130101) G01J 5/0853 (20130101) Original (OR) Class G01J 2005/068 (20130101) Optical Elements, Systems, or Apparatus G02B 1/11 (20130101) G02B 1/118 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/10 (20130101)
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10254231 — In-situ identification and control of microstructures produced by phase transformation of a material

US 10254231	Mazumder et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Jyotirmoy Mazumder (Ann Arbor, Michigan); Lijun Song (Ann Arbor, Michigan); Cunshan Wang (Dalian, China PRC)
ABSTRACT	A microstructure detector and in-situ method for real-time determination of the microstructure of a material undergoing alloying or other phase transformation. The method carried out by the detector includes the steps of: (a) detecting light emitted from a plasma plume created during phase transformation of a material; (b) determining at least some of the spectral content of the detected light; and (c) determining an expected microstructure of the transformed material from the determined spectral content. Closed loop control of the phase transformation process can be carried out using feedback from the detector to achieve a desired microstructure.
FILED	Tuesday, May 09, 2017
APPL NO	15/590780
ART UNIT	3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/718 (20130101) Original (OR) Class
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10254392 — Reverse-ephemeris method for determining position, attitude, and time

US 10254392	Reed et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Phillippe L. W. Reed (Charleston, South Carolina); Michael S. McBeth (Williamsburg, Virginia)
ABSTRACT	A method to calculate position of a platform using a detection and ranging system coupled to the platform to transmit a signal to space object having a known ephemeris. The detection and ranging system receives the reflected signal from the space object. Taking the range of the platform from the space object using a time delay between transmission of the signal and receipt of the reflected signal and the range-rate using a Doppler frequency shift between the transmission of the signal and the receipt of the reflected signal makes it possible to calculate a position fix of the platform using the determined range, the determined range-rate, an altitude of the platform, and the known ephemeris of the space object.
FILED	Wednesday, September 09, 2015
APPL NO	14/848626
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4808 (20130101) G01S 13/06 (20130101) G01S 13/42 (20130101) G01S 13/582 (20130101) Original (OR) Class G01S 13/588 (20130101) G01S 17/06 (20130101) G01S 17/50 (20130101)
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10254393 — Covariance matrix technique for error reduction

US 10254393	McCabe et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Denis Hugh McCabe (Fredericksburg, Virginia); James H. Africa, Jr. (Fredericksburg, Virginia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S)	Denis Hugh McCabe (Fredericksburg, Virginia); James H. Africa, Jr. (Fredericksburg, Virginia)
ABSTRACT	A method for filtering spatial error from a measurement vector is provided to correct for roll, pitch and yaw angular motion. The method includes the following operations: Establish an unstabilized body reference frame. Convert the measurement vector to an unstabilized state vector x_Uin the unstabilized body reference frame. Establish a stabilized East-North-Up (ENU) reference frame. Calculate an unstabilized pre-transform covariance matrix M_Ufrom position variance of the body reference frame. Measure roll, pitch and yaw in the body reference frame as respective angle values (r, p, w). Calculate a transform matrix T between the body reference frame and the ENU reference frame. Calculate a stabilized data vector x_S=Tx_Ufrom the transform matrix and the unstabilized state vector. Calculate a measured angle error sensitivity matrix M_Afrom the angle values. Calculate a tri-diagonal angle error component matrix M_Ewith square values of angle variance of the body reference frame. Calculate a total error covariance matrix P_S=M_AM_EM_A^T+TM_UT^T. Calculate a Kalman gain matrix for current time k+1 as K(k+1)=P(k+1\|k)H^T[HP(k+1\|k)H^T+P_S]⁻¹, where P(k+1\|k) is predicted gain covariance matrix from previous time k to the current time (k+1), and H is measurement Jacobian. Finally, apply the Kalman gain matrix to a predicted state estimate for correcting the measurement vector x_m.
FILED	Monday, March 28, 2016
APPL NO	15/083110
ART UNIT	2893 — Semiconductors/Memory
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/2955 (20130101) G01S 13/723 (20130101) Original (OR) Class
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10254453 — Thin-film broadband and wide-angle devices for generating and sampling polarization states

US 10254453	Pau et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S)	Stanley Pau (Tucson, Arizona); Wei-Liang Hsu (Tucson, Arizona)
ABSTRACT	Exemplary thin-film optical devices have first and second layer groups disposed as a layer stack on a substrate. The first layer group comprises a first PPN layer, a first LCP layer, and a first barrier layer all superposed. The second layer group is superposed relative to the first layer group, and includes a second PPN layer, a second LCP layer, and a second barrier layer all superposed. The first and second layer groups cooperate to polarize multiple wavelengths of an incident light flux in a broadband and/or wide-angle manner. Each of the layer groups has an alignment layer, a respective liquid-crystal polymer layer, and a barrier layer.
FILED	Friday, November 27, 2015
APPL NO	14/953272
ART UNIT	2871 — Optics
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/38 (20130101) C09K 19/56 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) G01J 2004/001 (20130101) Optical Elements, Systems, or Apparatus G02B 5/3016 (20130101) Original (OR) Class G02B 5/3058 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/133528 (20130101) G02F 1/133703 (20130101) G02F 1/133788 (20130101) G02F 2201/16 (20130101) G02F 2203/04 (20130101)
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10254481 — Integrated waveguide with reduced brillouin gain and a corresponding reduction in the magnitude of an induced stokes wave

US 10254481	Puckett et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S)	Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S)	Matthew Wade Puckett (Scottsdale, Arizona); Mary K. Salit (Plymouth, Minnesota)
ABSTRACT	An embodiment of an integrated waveguide is configured for reducing the level of Brillouin scattering, and for reducing the levels of at least some of the unwanted effects of Brillouin scattering. Such an integrated waveguide has a Brillouin gain, includes a cladding, and includes a core disposed within the cladding and configured to cause the Brillouin gain to be less than the Brillouin gain would be if the core were straight. For example, the core can be configured as a non-straight (e.g., meandering) core to reduce the Brillouin gain in an integrated waveguide, and, therefore, to reduce a level of coherent Brillouin scattering of an electromagnetic wave propagating through the waveguide. Therefore, a core so configured can reduce the energy of a counter-propagating Stokes wave induced by the propagating electromagnetic wave as compared to an otherwise comparable waveguide having a straight core.
FILED	Wednesday, June 28, 2017
APPL NO	15/636480
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) Original (OR) Class G02B 6/136 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0078 (20130101)
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10255070 — ISA extensions for synchronous coalesced accesses

US 10255070	Whelihan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	David Joseph Whelihan (Framingham, Massachusetts); Paul Stanton Keltcher (Lexington, Massachusetts)
ABSTRACT	Global synchrony changes the way computers can be programmed. A new class of ISA level instructions (the globally-synchronous load-store) of the present invention is presented. In the context of multiple load-store machines, the globally synchronous load-store architecture allows the programmer to think about a collection of independent load-store machines as a single load-store machine. These ISA instructions may be applied to a distributed matrix transpose or other data that exhibit a high degree of data non-locality and difficulty in efficiently parallelizing on modern computer system architectures. Included in the new ISA instructions are a setup instruction and a synchronous coalescing access instruction (“sca”). The setup instruction configures a head processor to set up a global map that corresponds processor data contiguously to the memory. The “sca” instruction configures processors to block processor threads until respective times on a global clock, derived from the global map, to access the memory.
FILED	Thursday, September 04, 2014
APPL NO	14/476848
ART UNIT	2183 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 9/52 (20130101) G06F 9/3009 (20130101) G06F 9/30087 (20130101) Original (OR) Class G06F 12/1425 (20130101) G06F 15/80 (20130101) G06F 2212/1052 (20130101)
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10255226 — Format agnostic data transfer method

US 10255226	Anderson et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Brent L. Anderson (Summerville, South Carolina); Justin Sellers (North Charleston, South Carolina); Lance Gorrell (Summerville, South Carolina); Jude Seeber (New York, New York)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Brent L. Anderson (Summerville, South Carolina); Justin Sellers (North Charleston, South Carolina); Lance Gorrell (Summerville, South Carolina); Jude Seeber (New York, New York)
ABSTRACT	A format agnostic data transfer system and methods for transferring between disparate components can include a transmitting component having a data push controller, a receiving component having a processor, and a memory connected to the processor. The data push controller can receive configuration instructions from the receiving component processor transfer said data to said memory, without requiring the use of direct memory access (DMA) at said transmitting component. The reconfigurable nature of the data push controller can allow for both fixed and variable stream data to be sent, making the system data format agnostic. The receiving component can be a processor, while the transmitting component can be a field programmable gate arrays (FPGA) or an application specific integrated circuits (ASIC).
FILED	Monday, October 22, 2018
APPL NO	16/167141
ART UNIT	2181 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 13/24 (20130101) G06F 13/28 (20130101) G06F 13/1673 (20130101) G06F 13/4286 (20130101) Original (OR) Class
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10255548 — Method and apparatus for modeling probability matching human subjects in n-arm bandit tasks

US 10255548	Chelian et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Inbound, Controlled, Air-Releasable, Unrecoverable Systems (ICARUS) Office of the Director of National Intelligence (ODNI) Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Suhas E. Chelian (San Jose, California); Rajan Bhattacharyya (Sherman Oaks, California)
ABSTRACT	Described is a system for modeling probability matching in human subjects. Features related to probability matching are extracted from a set of human subject responses from behavioral tasks. Neural network model instances are trained on the set of features, resulting in a set of trained neural network model instances. A set of model parameters are derived from the set of trained neural network instances, and the set of derived model parameters are used to emulate human performance on novel data.
FILED	Thursday, November 05, 2015
APPL NO	14/933414
ART UNIT	2121 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0472 (20130101) Original (OR) Class
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10255551 — Mixed-signal circuitry for computing weighted sum computation

US 10255551	Fick et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	The Regents of The University of Michigan (Ann Arbor, Michigan); Mythic, Inc. (Austin, Texas)
ASSIGNEE(S)	The Regents of The University of Michigan (Ann Arbor, Michigan); Mythic, Inc. (Austin, Texas)
INVENTOR(S)	David Alan Fick (Cedar Park, Texas); Laura E. Fick (Cedar Park, Texas); Skylar J. Skrzyniarz (Austin, Texas); Manar El-Chammas (Austin, Texas)
ABSTRACT	An integrated circuit and method are provided for performing weighted sum computations. The circuit includes: a plurality of current generators interconnected and arranged into pairs, a positive summation node, a negative summation node, and an input generation circuit. For each pair of current generators, the control terminal of each element is electrically connected to an input node. One of the current generators has its drain connected to the positive summation node while the other current generation element has its drain connected to the negative summation node. The remaining terminals on both current generators are connected to a reference, which may be shared. Each pair of current generator source predetermined amounts of current onto the two summation nodes when the following conditions occur: the input node is at an activation voltage, and the two summation nodes are at a predetermined target voltage.
FILED	Wednesday, February 07, 2018
APPL NO	15/890402
ART UNIT	2122 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 3/0635 (20130101) Pulse Technique H03K 5/24 (20130101)
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10256090 — Reduction of basal plane dislocations in epitaxial SiC using an in-situ etch process

US 10256090	Myers-Ward et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Rachael L. Myers-Ward (Springfield, Virginia); David Kurt Gaskill (Alexandria, Virginia); Charles R. Eddy, Jr. (Columbia, Maryland); Robert E. Stahlbush (Silver Spring, Maryland); Nadeemmullah A. Mahadik (Springfield, Virginia); Virginia D. Wheeler (Alexandria, Virginia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Rachael L. Myers-Ward (Springfield, Virginia); David Kurt Gaskill (Alexandria, Virginia); Charles R. Eddy, Jr. (Columbia, Maryland); Robert E. Stahlbush (Silver Spring, Maryland); Nadeemmullah A. Mahadik (Springfield, Virginia); Virginia D. Wheeler (Alexandria, Virginia)
ABSTRACT	A method of: providing an off-axis silicon carbide substrate, and etching the surface of the substrate with a dry gas, hydrogen, or an inert gas.
FILED	Tuesday, March 11, 2014
APPL NO	14/204045
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/20 (20130101) C30B 25/183 (20130101) C30B 29/36 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02378 (20130101) H01L 21/02433 (20130101) H01L 21/02447 (20130101) H01L 21/02529 (20130101) Original (OR) Class H01L 21/02658 (20130101) H01L 21/3065 (20130101) H01L 29/1608 (20130101)
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10256094 — Reduction of basal plane dislocations in epitaxial SiC using an in-situ etch process

US 10256094	Myers-Ward et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Rachael L. Myers-Ward (Springfield, Virginia); David Kurt Gaskill (Alexandria, Virginia); Charles R. Eddy, Jr. (Columbia, Maryland); Robert E. Stahlbush (Silver Spring, Maryland); Nadeemmullah A. Mahadik (Springfield, Virginia); Virginia D. Wheeler (Alexandria, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Rachael L. Myers-Ward (Springfield, Virginia); David Kurt Gaskill (Alexandria, Virginia); Charles R. Eddy, Jr. (Columbia, Maryland); Robert E. Stahlbush (Silver Spring, Maryland); Nadeemmullah A. Mahadik (Springfield, Virginia); Virginia D. Wheeler (Alexandria, Virginia)
ABSTRACT	A method of: providing an off-axis 4H—SiC substrate, and etching the surface of the substrate with hydrogen or an inert gas.
FILED	Tuesday, March 11, 2014
APPL NO	14/204015
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/20 (20130101) C30B 25/183 (20130101) C30B 29/36 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02378 (20130101) H01L 21/02433 (20130101) H01L 21/02447 (20130101) H01L 21/02529 (20130101) H01L 21/02617 (20130101) H01L 21/02658 (20130101) Original (OR) Class H01L 21/3065 (20130101)
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10256106 — Sacrificial shorting straps for superconducting qubits

US 10256106	Chang et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Office of the Director of National Intelligence (ODNI) Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Josephine B. Chang (Bedford Hills, New York); Douglas T. McClure, III (Rye, New York)
ABSTRACT	A technique relates to protecting a tunnel junction. A first electrode paddle and a second electrode paddle are on a substrate. The first and second electrode paddles oppose one another. A sacrificial shorting strap is formed on the substrate. The sacrificial shorting strap connects the first electrode paddle and the second electrode paddle; The tunnel junction is formed connecting the first electrode paddle and the second electrode paddle, after forming the sacrificial shorting strap. The substrate is mounted on a portion of a quantum cavity. The portion of the quantum cavity is placed in a vacuum chamber. The sacrificial shorting strap is etched away in the vacuum chamber while the substrate is mounted to the portion of the quantum cavity, such that the sacrificial shorting strap no longer connects the first and second electrode paddles. The tunnel junction has been protected from electrostatic discharge by the sacrificial shorting strap.
FILED	Friday, February 02, 2018
APPL NO	15/887297
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/3065 (20130101) Original (OR) Class H01L 29/66977 (20130101) H01L 39/025 (20130101) H01L 39/223 (20130101) H01L 39/2493 (20130101)
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10256334 — Gateless switch with capacitively-coupled contacts

US 10256334	Simin et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)	Sensor Electronic Technology, Inc. (Columbia, South Carolina)
ASSIGNEE(S)	Sensor Electronic Technology, Inc. (Columbia, South Carolina)
INVENTOR(S)	Grigory Simin (Columbia, South Carolina); Michael Shur (Latham, New York); Remigijus Gaska (Columbia, South Carolina)
ABSTRACT	A switch includes an input contact and an output contact to a conducting channel. At least one of the input and output contacts is capacitively coupled to the conducting channel. A control contact is located outside of a region between the input and output contacts, and can be used to adjust the switch between on and off operating states. The switch can be implemented as a radio frequency switch in a circuit.
FILED	Monday, April 25, 2016
APPL NO	15/137772
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 59/0009 (20130101) H01H 2001/0078 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) H01L 27/0605 (20130101) H01L 29/205 (20130101) H01L 29/0692 (20130101) H01L 29/772 (20130101) H01L 29/2003 (20130101) H01L 29/7787 (20130101) Original (OR) Class H01L 29/8605 (20130101) H01L 2223/6627 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2924/3011 (20130101) H01L 2924/12044 (20130101) H01L 2924/19032 (20130101) H01L 2924/19051 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/15 (20130101)
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10256362 — Flexible silicon infrared emitter

US 10256362	Augusto et al.
FUNDED BY	Department of Defense (DOD) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Andre Filipe Rodrigues Augusto (Tempe, Arizona); Stanislau Herasimenka (Tempe, Arizona); Stuart Bowden (Tempe, Arizona)
ABSTRACT	An apparatus includes a flexible silicon (Si) substrate, such as a crystalline n-type substrate, and a heterostructure structure formed on the silicon substrate. The heterojunction structure includes a first layered structured deposited on a first side of the silicon substrate. The first layered structured includes a first amorphous intrinsic silicon layer, an amorphous n-type or p-type silicon layer, and a transparent conductive layer. The second layered structure includes a second amorphous intrinsic silicon layer, an amorphous p-type or n-type silicon layer, and a transparent conductive layer. The heterostructure structure is configured to operate as a photovoltaic cell and an infrared light emitting diode.
FILED	Monday, July 31, 2017
APPL NO	15/665240
ART UNIT	2893 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/042 (20130101) H01L 31/125 (20130101) Original (OR) Class H01L 31/202 (20130101) H01L 31/0216 (20130101) H01L 31/0504 (20130101) H01L 31/0547 (20141201) H01L 31/0747 (20130101) H01L 31/1868 (20130101) H01L 31/1884 (20130101) H01L 31/02008 (20130101) H01L 31/03762 (20130101) H01L 31/022475 (20130101) H01L 31/035281 (20130101) H01L 33/22 (20130101) H01L 33/24 (20130101) H01L 33/34 (20130101) H01L 33/42 (20130101) H01L 33/46 (20130101) H01L 33/0058 (20130101) H01L 33/0095 (20130101) H01L 2933/0016 (20130101) H01L 2933/0025 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/38 (20141201)
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10256421 — Fusing porphyrins with polycyclic aromatic hydrocarbons and heterocycles for optoelectronic applications

US 10256421	Thompson et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of the Army (DOA) Department of Energy (DOE)
APPLICANT(S)	UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Abor, Michigan)
INVENTOR(S)	Mark E. Thompson (Anaheim, California); Viacheslav Diev (Wilmington, Delaware); Kenneth Hanson (Tallahassee, Florida); Stephen R. Forrest (Ann Arbor, Michigan)
ABSTRACT	A compound that can be used as a donor material in organic photovoltaic devices comprising a non-activated porphyrin fused with one or more non-activated polycyclic aromatic rings or one or more non-activated heterocyclic rings can be obtained by a thermal fusion process. The compounds include those having the following structure By heating the reaction mixture of non-activated porphyrins with non-activated polycyclic aromatic rings or heterocyclic rings to a fusion temperature and holding for a predetermined time, fusion of one or more polycyclic rings or heterocyclic rings to the non-activated porphyrin core in meso,β fashion is achieved resulting in hybrid structures containing a distorted porphyrin ring with annulated aromatic rings. The porphyrin core can be olygoporphyrins.
FILED	Monday, October 03, 2016
APPL NO	15/283958
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 487/22 (20130101) C07D 495/22 (20130101) C07D 513/22 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 47/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 2211/188 (20130101) C09K 2211/1007 (20130101) C09K 2211/1011 (20130101) C09K 2211/1029 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0072 (20130101) H01L 51/0077 (20130101) H01L 51/0092 (20130101) Original (OR) Class H01L 51/424 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/10 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101)
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10256546 — Dual-matrix composite embedded conductors and deployable structures

US 10256546	Costantine et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Joseph Costantine (Fullerton, California); Christos G. Christodoulou (Albuquerque, New Mexico); Youssef Antoine Tawk (Albuquerque, New Mexico); Christoph Benedikt Lukas Karl (Zurich, Switzerland); Nicolas Nik Lee (Redwood City, California); Ignacio Maqueda Jimenez (Madrid, Spain); Sergio Pellegrino (Pasadena, California); Maria Sakovsky (Pasadena, California)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Joseph Costantine (Fullerton, California); Christos G. Christodoulou (Albuquerque, New Mexico); Youssef Antoine Tawk (Albuquerque, New Mexico); Christoph Benedikt Lukas Karl (Zurich, Switzerland); Nicolas Nik Lee (Redwood City, California); Ignacio Maqueda Jimenez (Madrid, Spain); Sergio Pellegrino (Pasadena, California); Maria Sakovsky (Pasadena, California)
ABSTRACT	An antenna having a body that includes a plurality of rigid sections separated by a plurality of flexible sections and at least one conductor attached to the rigid and flexible sections. The flexible sections forming hinges that connect rigid sections together to permit the body to be configured into a conical configuration from a substantially flat trapezoid configuration.
FILED	Friday, May 06, 2016
APPL NO	15/148584
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/085 (20130101) H01Q 1/288 (20130101) H01Q 11/086 (20130101) Original (OR) Class
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10256600 — Hybrid photonic plasmonic interconnects (HyPPI) with intrinsic and extrinsic modulation options

US 10256600	Sun et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	The George Washington University (Washington, District of Columbia)
ASSIGNEE(S)	The George Washington University (Washington, District of Columbia)
INVENTOR(S)	Shuai Sun (Vienna, Virginia); Volker J. Sorger (Alexandria, Virginia); Tarek El-Ghazawi (Vienna, Virginia); Vikram K. Narayana (Ashburn, Virginia); Abdel-Hameed A. Badawy (Little Rock, Arkansas)
ABSTRACT	The Hybrid Photonic Plasmonic Interconnect (HyPPI) combines both low loss photonic signal propagation and passive routing with ultra-compact plasmonic devices. These optical interconnects therefore uniquely combine fast operational data-bandwidths (in hundreds of Gbps) for light manipulation with low optical attenuation losses by hybridizing low loss photonics with strong light-matter-interaction plasmonics to create, modulate, switch and detect light efficiently at the same time. Initial implementations were considered for on-chip photonic integration, but also promising for free space or fiber-based systems. In general two technical options exist, which distinguished by the method the electric-optic conversion is executed: the extrinsic modulation method consists of an continuous wave source such as an LED or laser operating at steady power output, and signal encoding is done via an electro-optic modulator downstream of the source in the interconnect. In contrast, in the intrinsic method, the optical source is directly amplitude modulated.
FILED	Monday, June 27, 2016
APPL NO	15/194119
ART UNIT	2884 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/12004 (20130101) G02B 2006/12121 (20130101) G02B 2006/12123 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0014 (20130101) Original (OR) Class H01S 5/0427 (20130101) H01S 5/1046 (20130101)
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10256698 — Fluid generator system

US 10256698	Marsh et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America as Represented by The Secretary of The Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by The Secretary of The Army (Washington, District of Columbia)
INVENTOR(S)	Charles P Marsh (Urbana, Illinois); Axy Pagan-Vazquez (Champaign, Illinois); Carl A Feickert (Champaign, Illinois); Aaron Averbuch (Champaign, Illinois); Meredith C. K. Sellers (Newark, California); Christopher Joel Foster (Champaign, Illinois); Scott M. Lux (Urbana, Illinois); Justin Hesterberg (Waterloo, Illinois); Andy Friedl (Boston, Massachusetts); John Alexander Magerko, III (Monument, Colorado)
ABSTRACT	The present invention is a fluid power generator with elastic tension gradient strips that move in a serpentine fashion to generate power from fluid flow. Each strip has a tension gradient that decreases going back. This allows steady serpentine movement of the strip to move a coil generator across multiple magnets to generate power. Tensioning tubes keep the strips under tension and attach the strips to a strip support that also supports a magnet holder. The magnet holder keeps the magnets in position within the coil generators so that any serpentine movement of the strip can generate power.
FILED	Thursday, September 29, 2016
APPL NO	15/279984
ART UNIT	2831 — Electrical Circuits and Systems
CURRENT CPC	Machines or Engines for Liquids F03B 13/10 (20130101) F03B 17/06 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/08 (20130101) Dynamo-electric Machines H02K 7/1876 (20130101) Original (OR) Class H02K 35/04 (20130101)
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10256902 — Detecting errors in optical messages

US 10256902	Tezak et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	Hewlett Packard Enterprise Development LP (Houston, Texas)
ASSIGNEE(S)	Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S)	Nikolas Anton Tezak (Palo Alto, California); David Kielpinski (Palo Alto, California); Jason Pelc (Palo Alto, California); Thomas Van Vaerenbergh (Palo Alto, California); Ranojoy Bose (Palo Alto, California); Raymond G. Beausoleil (Seattle, Washington)
ABSTRACT	In example implementations, an apparatus includes a bus waveguide, a plurality of optical gates coupled to the bus waveguide and an injection coupler. The bus waveguide receives a plurality of constraint signals. Each optical gate outputs an internal state via a local phase shift when at least one of the plurality of constraint signals has a wavelength that matches a respective resonant wavelength. The injection coupler combines the at least one of the plurality of constraint signals with additional constraint signals that are injected. An error is detected in a bit of a message when an overall phase shift has occurred to the at least one of the plurality of constraint signals causing a power level to exceed a power level threshold of an optical gate when the at least one of the plurality of constraint signals constructively interferes with the additional constraint signals that are injected.
FILED	Friday, November 13, 2015
APPL NO	15/775497
ART UNIT	2637 — Optical Communications
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/29331 (20130101) Transmission H04B 10/67 (20130101) H04B 10/07953 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 1/00 (20130101) H04L 1/20 (20130101)
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10256932 — Communication using chaotic waveforms

US 10256932	Swarup
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	AshRem Technologies, Inc. (Burbank, California)
ASSIGNEE(S)	ASHREM TECHNOLOGIES, INC. (Burbank, California)
INVENTOR(S)	Ashitosh Swarup (Burbank, California)
ABSTRACT	Example communication systems and methods are described. In one implementation, a method receives a first chaotic sequence of a first temporal length, and a second chaotic sequence of a second temporal length. The method also receives a data symbol for communication to a destination. Based on the data symbol, the second chaotic sequence is temporally shifted and combined with the first chaotic sequence to generate a composite chaotic sequence. The first chaotic sequence functions as a reference chaotic sequence while the second chaotic sequence functions as a data-carrying auxiliary chaotic sequence.
FILED	Friday, August 25, 2017
APPL NO	15/686783
ART UNIT	2632 — Digital Communications
CURRENT CPC	Multiplex Communication H04J 13/10 (20130101) H04J 13/0018 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0016 (20130101) H04L 27/001 (20130101) H04L 27/18 (20130101) H04L 27/2278 (20130101)
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10257002 — Zero-quiescent power receiver

US 10257002	Nguyen et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Clark T.-C. Nguyen (Oakland, California); Wei-Chang Li (San Jose, California); Ruonan Liu (Berkeley, California)
ABSTRACT	A microelectromechanical resonant switch (“resoswitch”) converts received radio frequency (RF) energy into an output signal with zero quiescent power usage by using a resonant element with a passband input sensitivity of: <−60 dBm, <−68 dBm, and <−100 dBm. The resoswitch first accepts incoming amplitude- or frequency-shift keyed RF energy at a carrier frequency, filters it, provides power gain via resonant impact switching, and finally envelop detects impact impulses to demodulate and recover the modulating waveform. Mechanical gain may be used to amplify received signals, whose amplitudes may be binned, thereby preserving use of amplitude modulated (AM) signals. A second resoswitch may be used to control additional circuitry, whereby the first resoswitch detects a control signal output to the additional circuitry.
FILED	Monday, June 19, 2017
APPL NO	15/627142
ART UNIT	2632 — Digital Communications
CURRENT CPC	Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 59/0009 (20130101) Transmission H04B 1/713 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/152 (20130101) Original (OR) Class H04L 67/12 (20130101) H04L 2027/0091 (20130101) Wireless Communication Networks H04W 52/0229 (20130101)
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Department of Energy (DOE)

10252924 — Purification of ultra-high saline and contaminated water by multi-stage ion concentration polarization (ICP) desalination

US 10252924	Kim et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Bumjoo Kim (Malden, Massachusetts); Jongyoon Han (Bedford, Massachusetts); Rhokyun Kwak (Seoul, South Korea); Bader Shafaqa Al-Anzi (Safat, Kuwait)
ABSTRACT	A water stream is passed between two juxtaposed similar ion exchange membranes (AEMs or CEMs), forming an ion depletion and ion enrichment zones when an electric field is applied. As cations are selectively transferred through the CEMs, for example, anions are relocated in order to achieve electro-neutrality, resulting in the concentration drop (increase) in ion depletion (enrichment) zone. Trifurcation of the output channel allows collection of concentrated, dilute and intermediate streams, with the intermediate stream serving as input to the next stage of a serialized implementation.
FILED	Friday, October 23, 2015
APPL NO	14/920992
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Separation B01D 61/42 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/469 (20130101) C02F 1/4604 (20130101) C02F 1/4695 (20130101) Original (OR) Class C02F 1/4698 (20130101) C02F 2101/10 (20130101) C02F 2101/30 (20130101) C02F 2101/32 (20130101) C02F 2103/08 (20130101) C02F 2201/46115 (20130101) C02F 2301/04 (20130101) C02F 2301/08 (20130101)
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10253195 — Coreactive materials and methods for three-dimensional printing

US 10253195	Fenn et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	PPG Industries Ohio, Inc. (Cleveland, Ohio)
ASSIGNEE(S)	PPG Industries Ohio, Inc. (Cleveland, Ohio)
INVENTOR(S)	David R. Fenn (Allison Park, Pennsylvania); Kurt G. Olson (Gibsonia, Pennsylvania); Reza M. Rock (Pittsburgh, Pennsylvania); Cynthia Kutchko (Pittsburgh, Pennsylvania); Susan F. Donaldson (Allison Park, Pennsylvania); Hao Sun (Allison Park, Pennsylvania)
ABSTRACT	Methods of printing a three-dimensional object using co-reactive components are disclosed. Thermosetting compositions for three-dimensional printing are also disclosed.
FILED	Tuesday, November 24, 2015
APPL NO	15/528205
ART UNIT	1785 — Miscellaneous Articles, Stock Material
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2075/02 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/10 (20130101) C08G 18/10 (20130101) C08G 18/73 (20130101) C08G 18/325 (20130101) C08G 18/755 (20130101) C08G 18/792 (20130101) C08G 18/3225 (20130101) C08G 18/3228 (20130101) C08G 18/3234 (20130101) C08G 18/3821 (20130101) C08G 18/4854 (20130101) C08G 18/5024 (20130101) C08G 18/6685 (20130101) C08G 18/7893 (20130101) C08G 2150/50 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/03 (20130101) C09D 11/30 (20130101) C09D 11/38 (20130101) C09D 11/102 (20130101) Original (OR) Class C09D 175/02 (20130101)
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10253261 — Stimuli-responsive liquid crystalline networks

US 10253261	Li et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee); Washington State University (Pullman, Washington)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee); WASHINGTON STATE UNIVERSITY (Pullman, Washington)
INVENTOR(S)	Yuzhan Li (Pullman, Washington); Orlando Rios (Knoxville, Tennessee); Michael Richard Kessler (Pullman, Washington)
ABSTRACT	Liquid crystalline network compositions comprising azo-containing aromatic epoxy units cross-linked with alkylene diacid units having alkylene segments containing at least one methylene unit, wherein the azo-containing aromatic epoxy units and alkylene diacid units are connected by ester linkages resulting from ring-opening esterification between the epoxy units and alkylene diacids, and wherein the azo-containing aromatic epoxy units and alkylene diacid units are in a molar ratio that results in the liquid crystalline network composition exhibiting a glass transition temperature (T_g) of at least 25° C. Methods for producing these compositions and their use in light- or thermal-activated physical deformation, shape memory applications, and self-healing, as well as their ability to be recycled and used in additive manufacturing processes are also described.
FILED	Thursday, January 19, 2017
APPL NO	15/409717
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/28 (20130101) C08G 59/686 (20130101) C08G 59/4207 (20130101) C08G 2280/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/3814 (20130101) Original (OR) Class
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10253325 — Methods for elevating fat/oil content in plants

US 10253325	Puri et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	BOSTON MEDICAL CENTER CORPORATION (Boston, Massachusetts); UNIVERSITY OF NORTH TEXAS (Denton, Texas)
ASSIGNEE(S)	BOSTON MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S)	Vishwajeet Puri (Hopkinton, Massachusetts); Kent Chapman (Denton, Texas); Christopher James (Argyle, Texas)
ABSTRACT	In some embodiments, the present invention provides a method of elevating lipid content in vegetative (non-seed) plant or algae cells, plant tissues, or whole plants by genetically modifying the plant or algae to express a lipid droplet-associated protein or polypeptide (such as fat-specific protein 27) of mammalian origin. Also provided are genetically-modified plant or algae cells, plant tissues, or whole plants with elevated cellular lipid content, expressing a lipid droplet-associated protein or polypeptide (such as fat-specific protein 27) of mammalian (e.g. human) origin.
FILED	Thursday, March 14, 2013
APPL NO	13/830012
ART UNIT	1662 — Plants
CURRENT CPC	Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6463 (20130101)
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10253338 — Conversion of biomass to useful intermediates

US 10253338	Beckham et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S)	Gregg Tyler Beckham (Golden, Colorado); Christopher W. Johnson (Denver, Colorado); Derek R. Vardon (Lakewood, Colorado)
ABSTRACT	An aspect of the present disclosure is a microbial cell that includes a genetic modification resulting in the expression of a deficient form of an endogenous dioxygenase, and a gene encoding an exogenous dioxygenase and a promoter sequence, where the endogenous dioxygenase includes PcaH and PcaG, the exogenous dioxygenase includes LigA and LigB, the microbial cell is capable of growth utilizing at least one of a cellulose decomposition molecule or a lignin decomposition molecule, and the microbial cell is capable of producing 2-hydroxy-2H-pyran-4,6-dicarboxylic acid.
FILED	Thursday, March 23, 2017
APPL NO	15/467761
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/13 (20130101) C12N 9/18 (20130101) C12N 9/0069 (20130101) C12N 9/88 (20130101) C12N 9/90 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/44 (20130101) Original (OR) Class Enzymes C12Y 101/01312 (20130101) C12Y 102/01085 (20150701) C12Y 113/11001 (20130101) C12Y 113/11003 (20130101) C12Y 113/11008 (20130101) C12Y 208/03006 (20130101) C12Y 301/01024 (20130101) C12Y 301/01057 (20130101) C12Y 307/01009 (20130101) C12Y 401/01044 (20130101) C12Y 401/01045 (20130101) C12Y 401/01077 (20130101) C12Y 402/01083 (20130101) C12Y 503/02 (20130101) C12Y 503/02006 (20150701) C12Y 503/03004 (20130101) C12Y 505/01001 (20130101) C12Y 505/01002 (20130101)
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10253342 — Polypeptides having catalase activity and polynucleotides encoding same

US 10253342	Liu et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Novozymes Inc. (Davis, California)
ASSIGNEE(S)	Novozymes Inc. (Davis, California)
INVENTOR(S)	Ye Liu (Beijing, China PRC); Junxin Duan (Beijing, China PRC); Yu Zhang (Beijing, China PRC); Lan Tang (Beijing, China PRC)
ABSTRACT	The present invention relates to isolated polypeptides having catalase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
FILED	Monday, August 06, 2018
APPL NO	16/055431
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0065 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) C12P 19/02 (20130101) Original (OR) Class C12P 2201/00 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 111/01006 (20130101) Dry-cleaning, Washing or Bleaching Fibres, Filaments, Threads, Yarns, Fabrics, Feathers or Made-up Fibrous Goods; Bleaching Leather or Furs D06L 4/40 (20170101)
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10253559 — Energy-harvesting chromogenic devices

US 10253559	Wheeler
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S)	Lance M. Wheeler (Wheat Ridge, Colorado)
ABSTRACT	An aspect of the present disclosure is a device that includes a switchable material and an intercalating species, such that when a first condition is met, at least a portion of the intercalating species is associated with the switchable material and the switchable material is substantially transparent and substantially colorless, and when a second condition is met, at least a fraction of the portion of the intercalating species is transferred from the switchable material and the switchable material is substantially transparent and substantially colored.
FILED	Wednesday, September 28, 2016
APPL NO	15/279062
ART UNIT	2872 — Optics
CURRENT CPC	Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 4/06 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/24 (20130101) Original (OR) Class E06B 2009/2464 (20130101) E06B 2009/2476 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/15 (20130101) G02F 1/0126 (20130101) G02F 1/0147 (20130101) G02F 1/153 (20130101) G02F 1/155 (20130101) G02F 1/1533 (20130101) G02F 2201/08 (20130101) G02F 2201/086 (20130101) G02F 2202/36 (20130101) G02F 2203/11 (20130101) G02F 2203/62 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0077 (20130101) H01L 51/0083 (20130101) H01L 51/4213 (20130101)
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10253620 — System for kick detection during a drilling operation

US 10253620	Rose et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM) National Energy Technology Laboratory (NETL)
APPLICANT(S)	Kelly K. Rose (Albany, Oregon); Brian C. Tost (Albany, Oregon); Fred Aminzadeh (Woodland Hills, California)
ASSIGNEE(S)
INVENTOR(S)	Kelly K. Rose (Albany, Oregon); Brian C. Tost (Albany, Oregon); Fred Aminzadeh (Woodland Hills, California)
ABSTRACT	The disclosure provides a kick detection system for use during a drilling operation where wellbore kick warnings are provided based on indications of standoff conditions in a compensated instrument system. The system provides a warning of a potential kick condition by analyzing a current instrument compensation against a time series of past compensations, in order to monitor whether conditions within the standoff region of the wellbore are unexpectedly changing. The system comprises a source, a short-spaced detector, and a long-spaced detector, and a processor receives the short-spaced signal and the long-spaced signal, compensates the long-spaced signal, and generates standoff data reflecting the corrections applied to the long-range signal. The processor determines and maintains the standoff data as a time series and periodically compares a recent data point to a moving average in order to evaluate indications of a potential well kick.
FILED	Monday, September 14, 2015
APPL NO	14/852845
ART UNIT	2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC	Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 47/00 (20130101) E21B 47/01 (20130101) E21B 47/14 (20130101) E21B 47/101 (20130101) E21B 47/102 (20130101) Original (OR) Class E21B 47/122 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/48 (20130101) G01V 3/30 (20130101) G01V 5/10 (20130101) G01V 5/125 (20130101) G01V 11/00 (20130101)
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10253986 — Article and method of forming an article

US 10253986	Lacy et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Benjamin Paul Lacy (Greer, South Carolina); Srikanth Chandrudu Kottilingam (Simpsonville, South Carolina); Sandip Dutta (Greenville, South Carolina); David Edward Schick (Greenville, South Carolina)
ABSTRACT	A cooling article and method of forming a cooling article are provided. The cooling article includes a body portion separating an inner region and an outer region, an aperture in the body portion, the aperture fluidly connecting the inner region to the outer region, and a cooling feature extending away from an outer surface of the body portion. The cooling feature disturbs fluid flow in the outer region. The method of forming a cooling article includes forming a body portion defining an inner region and an outer region, forming an aperture in the body portion, the aperture fluidly connecting the inner region to the outer region, and forming a cooling feature extending away from an outer surface of the body portion. The cooling article is arranged and disposed for insertion within a hot gas path component of a turbine engine.
FILED	Tuesday, September 08, 2015
APPL NO	14/847347
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 5/04 (20130101) B22F 5/009 (20130101) B22F 5/10 (20130101) B22F 2005/005 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/188 (20130101) F01D 5/189 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/31 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/06 (20130101) Original (OR) Class F23R 2900/03045 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101)
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10254112 — Full-field surface roughness

US 10254112	Kemme et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Shanalyn A. Kemme (Albuquerque, New Mexico); Adam Jones (Tijeras, New Mexico); George Burns (Albuquerque, New Mexico)
ABSTRACT	The various embodiments presented herein relate to utilizing light in conjunction with an optical Fourier transform to examine and quantify roughness of a surface. The surface includes a plurality of flaked particles. The surface is illuminated with a light beam, wherein light reflected from the surface passes through an f-theta lens and is collected at a light sensitive array (LSA). The LSA comprises light sensitive pixels. For an arrangement where the flakes are conformal with the surface, a low degree of light scattering occurs at the surface. For a surface comprising tipped and/or tilted flakes, a correlating degree of scattering of the incident light beam occurs. The surface roughness is quantified based upon the distribution of angular reflections of the scattered light represented in an image formed through use of the LSA.
FILED	Thursday, October 29, 2015
APPL NO	14/927037
ART UNIT	2886 — Optics
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/303 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/10 (20130101)
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10254248 — Collection, release, and detection of analytes with polymer composite sampling materials

US 10254248	Addleman et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Raymond S Addleman (Benton City, Washington); Xiaohong Shari Li (Richland, Washington); Wilaiwan Chouyyok (West Richland, Washington); David A Atkinson (Richland, Washington)
ABSTRACT	A unique fiber core sampler composition, related systems, and techniques for designing, making, and using the same are described. The sampler is used to interface with existing field instrumentation, such as Ion Mobility Spectrometer (IMS) equipment. Desired sampler characteristics include its: stiffness/flexibility; thermal mass and conductivity; specific heat; trace substance collection/release dependability, sensitivity and repeatability; thickness; reusability; durability; stability for thermal cleaning; and the like. In one form the sampler has a glass fiber core with a thickness less than 0.3 millimeter that is coated with a polymer including one or more of: polymeric organofluorine, polyimide, polyamide, PolyBenzlmidazole (PBI), PolyDiMethylSiloxane (PDMS), sulfonated tetrafluoroethylene (PFSA) and Poly(2,6-diphenyl-p-phenylene Oxide) (PPPO). Multiple polymer coatings with the same or different polymer types may be included, core/substrate surface functionalization utilized, and/or the core/substrate may be at partially filled with thermally conductive particles.
FILED	Tuesday, April 21, 2015
APPL NO	14/692460
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) G01N 1/405 (20130101) G01N 27/622 (20130101) Original (OR) Class G01N 2001/024 (20130101) G01N 2001/027 (20130101) G01N 2001/028 (20130101) G01N 2001/4061 (20130101)
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10254298 — Detection of metabolites for controlled substances

US 10254298	Koh
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Chung-Yan Koh (Dublin, California)
ABSTRACT	The various technologies presented herein relate to identifying whether an individual has taken, and/or is under the influence of, a restricted drug. A density separation technique is utilized, wherein a sample (e.g., blood, saliva, urine, etc.,) which may include an analyte is exposed to a first plurality of beads having an analyte attached thereto, a second plurality of beads having a metabolite-specific antibody attached thereto, and a plurality of fluorophore-labelled analyte-specific antibodies. After incubation, any analyte in the sample (e.g., delta-9-THC) is bound to the fluorophore-labelled analyte-specific antibodies, any free fluorophore-labelled analyte-specific antibodies are attached to the analyte of the first beads, and any metabolite in the sample is bound to the second antibody. By applying centrifugal separation, the first beads move to a region which undergoes irradiation. If no fluorescence occurs, the sample includes the analyte; if fluorescence occurs, the sample does not include the analyte.
FILED	Wednesday, December 02, 2015
APPL NO	14/957405
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/948 (20130101) Original (OR) Class G01N 2021/6439 (20130101)
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10254334 — Test circuits for integrated circuit counterfeit detection

US 10254334	Helinski et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Ryan Helinski (Albuquerque, New Mexico); Lyndon G. Pierson (Albuquerque, New Mexico); Edward I. Cole (Albuquerque, New Mexico); Tan Q. Thai (Albuquerque, New Mexico)
ABSTRACT	Described herein are various technologies pertaining to identifying counterfeit integrated circuits (ICs) by way of allowing the origin of fabrication to be verified. An IC comprises a main circuit and a test circuit that is independent of the main circuit. The test circuit comprises at least one ring oscillator (RO) signal that, when energized, is configured to output a signal that is indicative of a semiconductor fabrication facility where the IC was manufactured.
FILED	Tuesday, July 24, 2018
APPL NO	16/044007
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2856 (20130101) G01R 31/2894 (20130101) Original (OR) Class G01R 31/31703 (20130101) G01R 31/31703 (20130101) G01R 31/31703 (20130101) G01R 31/31708 (20130101) G01R 31/31708 (20130101) G01R 31/31708 (20130101) Pulse Technique H03K 19/003 (20130101) H03K 19/003 (20130101) H03K 19/003 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3247 (20130101) H04L 9/3247 (20130101) H04L 9/3247 (20130101) H04L 9/3247 (20130101) H04L 9/3255 (20130101) H04L 9/3255 (20130101) H04L 9/3255 (20130101) H04L 9/3281 (20130101)
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10254399 — Small mover target detection in synthetic aperture radar imagery

US 10254399	Simonson et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Katherine M. Simonson (Cedar Crest, New Mexico); David Nikolaus Perkins (Albuquerque, New Mexico); Jeffrey A. Brooks (Albuquerque, New Mexico); Roger Derek West (Albuquerque, New Mexico); Ivan Lizarraga (Albuquerque, New Mexico); Matthew Strosnick (Mountain View, California); David A. Torgesen (Albuquerque, New Mexico)
ABSTRACT	The various technologies presented herein relate to detecting small moving entities or targets in radar imagery. Two SAR images can be captured for a common scene, wherein the scene is imaged twice from the same flight path. The first image is captured at a first instance and the second image is captured at a second instance, and differences between the two images are determined using a complex SAR change measure, excess coherency factor or DeltaC, based in part upon quantification of incoherent (or magnitude) change between the two images. A plurality of operations are performed to enable extraction of coherent change measures relating to the small moving entities from measures relating to large objects, stationary reflective structures, radar focusing artifacts, etc.
FILED	Wednesday, December 02, 2015
APPL NO	14/957394
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/9029 (20130101) Original (OR) Class
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10254721 — Cascaded systems and methods for controlling energy use during a demand limiting period

US 10254721	Wenzel et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Johnson Controls Technology Company (Holland, Michigan)
ASSIGNEE(S)	Johnson Controls Technology Company (Auburn Hills, Michigan)
INVENTOR(S)	Michael J. Wenzel (Oak Creek, Wisconsin); Kirk H. Drees (Cedarburg, Wisconsin)
ABSTRACT	A cascaded control system is configured to control power consumption of a building during a demand limiting period. The cascaded control system includes an energy use setpoint generator and a feedback controller. The energy use setpoint generator is configured to use energy pricing data and measurements of a variable condition within the building to generate an energy use setpoint during the demand limiting period. The feedback controller is configured to use a difference between the energy use setpoint and a measured energy use to generate a control signal for building equipment that operate to affect the variable condition within the building during the demand limiting period.
FILED	Friday, March 11, 2016
APPL NO	15/068475
ART UNIT	2117 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/30 (20180101) F24F 11/46 (20180101) F24F 11/62 (20180101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/021 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 23/1923 (20130101) Systems for Regulating Electric or Magnetic Variables G05F 1/66 (20130101) Electric Digital Data Processing G06F 1/3203 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0201 (20130101) G06Q 30/0202 (20130101) G06Q 30/0206 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/14 (20130101) H04L 12/2803 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/84 (20151101) Y02P 90/845 (20151101)
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10255132 — System and method for protecting GPU memory instructions against faults

US 10255132	Kalamatianos et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Advanced Micro Devices, Inc. (Sunnyvale, California)
ASSIGNEE(S)	Advanced Micro Devices, Inc. (Sunnyvale, California)
INVENTOR(S)	John Kalamatianos (Boxborough, Massachusetts); Michael Mantor (Orlando, Florida); Sudhanva Gurumurthi (Austin, Texas)
ABSTRACT	A system and method for protecting memory instructions against faults are described. The system and method include converting the slave instructions to dummy operations, modifying memory arbiter to issue up to N master and N slave global/shared memory instructions per cycle, sending master memory requests to memory system, using slave requests for error checking, entering master requests to the GM/LM FIFO, storing slave requests in a register, and comparing the entered master requests with the stored slave requests.
FILED	Wednesday, June 22, 2016
APPL NO	15/190015
ART UNIT	2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electric Digital Data Processing G06F 11/1064 (20130101) Original (OR) Class G06F 11/1629 (20130101) G06F 12/0866 (20130101) G06F 2212/281 (20130101) G06F 2212/403 (20130101) G06F 2212/1032 (20130101)
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10255191 — Logical memory address regions

US 10255191	Farmahini-Farahani et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Advanced Micro Devices, Inc. (Sunnyvale, California)
ASSIGNEE(S)	Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S)	Amin Farmahini-Farahani (Santa Clara, California); David A. Roberts (Cambridge, Massachusetts)
ABSTRACT	Systems, apparatuses, and methods for implementing logical memory address regions in a computing system. The physical memory address space of a computing system may be partitioned into a plurality of logical memory address regions. Each logical memory address region may be dynamically configured at run-time to meet changing application needs of the system. Each logical memory address region may also be configured separately from the other logical memory address regions. Each logical memory address region may have associated parameters that identify region start address, region size, cell-level mode, physical-to-device mapping scheme, address masks, access permissions, wear-leveling data, encryption settings, and compression settings. These parameters may be stored in a table which may be used when processing memory access requests.
FILED	Tuesday, April 19, 2016
APPL NO	15/133033
ART UNIT	2131 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0616 (20130101) G06F 3/0644 (20130101) G06F 3/0665 (20130101) G06F 3/0683 (20130101) G06F 12/0238 (20130101) G06F 12/1009 (20130101) Original (OR) Class G06F 12/1408 (20130101) G06F 12/1441 (20130101) G06F 2212/205 (20130101) G06F 2212/401 (20130101) G06F 2212/402 (20130101) G06F 2212/1016 (20130101) G06F 2212/1052 (20130101) G06F 2212/7201 (20130101) G06F 2212/7211 (20130101)
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10255355 — Method and system for information retrieval and aggregation from inferred user reasoning

US 10255355	Endert et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Alexander Endert (Spartanburg, South Carolina); Nicholas O. Cramer (Richland, Washington); Ralph J. Perko, III (Richland, Washington); Shawn D. Hampton (Kennewick, Washington); Edwin R. Burtner (Richland, Washington); Kristin A. Cook (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Alexander Endert (Spartanburg, South Carolina); Nicholas O. Cramer (Richland, Washington); Ralph J. Perko, III (Richland, Washington); Shawn D. Hampton (Kennewick, Washington); Edwin R. Burtner (Richland, Washington); Kristin A. Cook (Richland, Washington)
ABSTRACT	The visual analytic system enables information retrieval within large text collections. Typically, users have to directly and explicitly query information to retrieve it. With this system and process, the reasoning of the user is inferred from the user interaction they perform in a visual analytic tool, and the appropriate information to query, process, and visualize is systematically determined.
FILED	Wednesday, May 27, 2015
APPL NO	14/723391
ART UNIT	2168 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 17/30412 (20130101) G06F 17/30554 (20130101) G06F 17/30643 (20130101) G06F 17/30713 (20130101) G06F 17/30719 (20130101) Original (OR) Class
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10255393 — Optimally placing photovoltaic arrays to maximize value of energy production based on peak power production, local solar radiation, weather, electricity market prices and rate structures

US 10255393	Webber et al.
FUNDED BY	Department of Energy (DOE) Office of Electricity (DOE-OE)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Michael E. Webber (Austin, Texas); Joshua D. Rhodes (Austin, Texas); Charles R. Upshaw (Austin, Texas)
ABSTRACT	A method, system and computer program product for optimally placing photovoltaic arrays to maximize a value of energy production. Incident solar radiation for various placements of the photovoltaic arrays accommodating different azimuths and tilts is calculated. Alternating current solar photovoltaic electricity energy and power production is then estimated from the calculated solar radiation on a plane and weather data. Furthermore, a value of solar photovoltaic electricity energy and power produced by the photovoltaic arrays for the various placements is calculating using the estimated alternating current solar photovoltaic electricity production. A placement out of the various placements for the photovoltaic arrays is then selected corresponding to a highest value of the solar photovoltaic electricity produced by the photovoltaic arrays. In this manner, the appropriate placement for the photovoltaic arrays is determined that maximizes the value of energy production (where “value” may correspond to an economic value or a non-economic value).
FILED	Thursday, May 28, 2015
APPL NO	14/724276
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Electric Digital Data Processing G06F 17/5004 (20130101) G06F 17/5018 (20130101) Original (OR) Class G06F 2217/78 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) Y02E 40/76 (20130101) Y02E 60/76 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/545 (20130101) Y04S 40/22 (20130101)
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10256067 — Low voltage drop, cross-field, gas switch and method of operation

US 10256067	Sommerer et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	General Electric Company (Schenectady, New York); Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Timothy John Sommerer (Ballston Spa, New York); David John Smith (Clifton Park, New York); Joseph Darryl Michael (Delmar, New York); Steven Charles Aceto (Wynantskill, New York); Kirk Ernest Marquard (Burlington, Connecticut); Jason Fredrick Trotter (Glenville, New York); James E. Lawler (Madison, Wisconsin); William Nicholas Guy Hitchon (Verona, Wisconsin)
ABSTRACT	A gas switch includes an anode and a cathode spaced apart from the anode, wherein the cathode includes a conduction surface. The gas switch also includes a plurality of magnets arranged to generate a magnetic field that defines an annular path over a portion of the conduction surface at a radial distance from a switch axis, and a control grid positioned between the anode and the cathode. In operation, the control grid is arranged to establish a conducting plasma between the anode and the cathode, wherein, in the presence of the conducting plasma, a voltage drop between the anode and the cathode is less than 150 volts, and wherein the conducting plasma forms a cathode spot that circles the annular path.
FILED	Tuesday, January 02, 2018
APPL NO	15/860225
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 17/14 (20130101) Original (OR) Class H01J 17/44 (20130101) H01J 17/64 (20130101)
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10256072 — Optimized sub-sampling in an electron microscope

US 10256072	Stevens et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Andrew J. Stevens (Richland, Washington); Libor Kovarik (West Richland, Washington); Andrey V. Liyu (Pasco, Washington); Nigel D. Browning (Richland, Washington)
ABSTRACT	Disclosed are methods for optimized sub-sampling in an electron microscope. With regard at least to utilization of electron dose budgets, of time for acquisition of measurements, and of computing/processing capabilities, very high efficiencies can be achieved by informing and/or adapting subsequent sub-sampling measurements according to one or more earlier-acquired sparse datasets and/or according to analyzes thereof.
FILED	Tuesday, August 01, 2017
APPL NO	15/666159
ART UNIT	2881 — Optics
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/00134 (20130101) Image Data Processing or Generation, in General G06T 5/005 (20130101) G06T 2207/10061 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/28 (20130101) H01J 37/244 (20130101) H01J 37/265 (20130101) Original (OR) Class
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10256085 — Zero voltage mass spectrometry probes and systems

US 10256085	Cooks et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Robert Graham Cooks (West Lafayette, Indiana); Michael Stanley Wleklinski (Indianapolis, Indiana); Soumabha Bag (West Lafayette, Indiana); Yafeng Li (Beijing, China PRC)
ABSTRACT	The invention generally relates to zero volt mass spectrometry probes and systems. In certain embodiments, the invention provides a system including a mass spectrometry probe including a porous material, and a mass spectrometer (bench-top or miniature mass spectrometer). The system operates without an application of voltage to the probe. In certain embodiments, the probe is oriented such that a distal end faces an inlet of the mass spectrometer. In other embodiments, the distal end of the probe is 5 mm or less from an inlet of the mass spectrometer.
FILED	Thursday, September 07, 2017
APPL NO	15/697560
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/0013 (20130101) H01J 49/0436 (20130101) Original (OR) Class
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10256093 — Selective area growth of semiconductors using patterned sol-gel materials

US 10256093	Warren et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S)	Emily L. Warren (Golden, Colorado); Adele Clare Tamboli (Golden, Colorado)
ABSTRACT	Systems and methods for growing semiconductor materials on substrates by using patterned sol-gel materials are provided. According to a first aspect of the invention, a method includes forming a pattern of a sol-gel material on a first region of substrate, and depositing a semiconductor material on a second region of the substrate by selective area growth. The second region is adjacent to the first region.
FILED	Monday, November 28, 2016
APPL NO	15/362420
ART UNIT	2817 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02381 (20130101) H01L 21/02546 (20130101) H01L 21/02639 (20130101) H01L 21/02642 (20130101) H01L 21/02647 (20130101) Original (OR) Class
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10256352 — Structures for nitride vertical transistors

US 10256352	Sun et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Min Sun (Cambridge, Massachusetts); Tomas Apostol Palacios (Belmont, Massachusetts)
ABSTRACT	A vertical semiconductor transistor and a method of forming the same. A vertical semiconductor transistor has at least one semiconductor region, a source, and at least one gate region. The at least one semiconductor region includes a III-nitride semiconductor material. The source is formed over the at least one semiconductor region. The at least one gate region is formed around at least a portion of the at least one semiconductor region.
FILED	Thursday, December 22, 2016
APPL NO	15/388963
ART UNIT	2829 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 29/0649 (20130101) H01L 29/0657 (20130101) H01L 29/0676 (20130101) H01L 29/2003 (20130101) H01L 29/7813 (20130101) H01L 29/7827 (20130101) H01L 29/8083 (20130101) H01L 29/8122 (20130101) Original (OR) Class H01L 29/66666 (20130101)
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10256361 — Multiple band gap Co-Ni oxide compositions and applications thereof

US 10256361	Carter et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S)	Emily Ann Carter (Mead, New Jersey); Nima Alidoust (Princeton, New Jersey); Martina Lessio (Lawrenceville, New Jersey)
ABSTRACT	In one aspect, metal oxide compositions having electronic structure of multiple band gaps are described. In some embodiments, a metal oxide composition comprises a (Co,Ni)O alloy having electronic structure including multiple band gaps. The (Co,Ni)O alloy can include a first band gap and a second band gap, the first band gap separating valence and conduction bands of the electronic structure.
FILED	Monday, August 29, 2016
APPL NO	15/250633
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/40 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/77 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/032 (20130101) H01L 31/0687 (20130101) Original (OR) Class H01L 33/26 (20130101)
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10256421 — Fusing porphyrins with polycyclic aromatic hydrocarbons and heterocycles for optoelectronic applications

US 10256421	Thompson et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of the Army (DOA) Department of Energy (DOE)
APPLICANT(S)	UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Abor, Michigan)
INVENTOR(S)	Mark E. Thompson (Anaheim, California); Viacheslav Diev (Wilmington, Delaware); Kenneth Hanson (Tallahassee, Florida); Stephen R. Forrest (Ann Arbor, Michigan)
ABSTRACT	A compound that can be used as a donor material in organic photovoltaic devices comprising a non-activated porphyrin fused with one or more non-activated polycyclic aromatic rings or one or more non-activated heterocyclic rings can be obtained by a thermal fusion process. The compounds include those having the following structure By heating the reaction mixture of non-activated porphyrins with non-activated polycyclic aromatic rings or heterocyclic rings to a fusion temperature and holding for a predetermined time, fusion of one or more polycyclic rings or heterocyclic rings to the non-activated porphyrin core in meso,β fashion is achieved resulting in hybrid structures containing a distorted porphyrin ring with annulated aromatic rings. The porphyrin core can be olygoporphyrins.
FILED	Monday, October 03, 2016
APPL NO	15/283958
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 487/22 (20130101) C07D 495/22 (20130101) C07D 513/22 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 47/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 2211/188 (20130101) C09K 2211/1007 (20130101) C09K 2211/1011 (20130101) C09K 2211/1029 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0072 (20130101) H01L 51/0077 (20130101) H01L 51/0092 (20130101) Original (OR) Class H01L 51/424 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/10 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101)
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10256504 — Ionic conductivity of NASICON through aliovalent cation substitution

US 10256504	Wachsman et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S)	University of Maryland (College Park, Maryland)
INVENTOR(S)	Eric D. Wachsman (Fulton, Maryland); Adam Jolley (College Park, Maryland)
ABSTRACT	The present invention is directed to solid NASICON electrolytes in which the zirconium site is doped with a 2+ oxidation state cation. The present invention is also directed to methods of making the solid electrolytes and methods of using the solid electrolytes in batteries and other electrochemical technologies.
FILED	Wednesday, March 09, 2016
APPL NO	15/065560
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/054 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 10/0585 (20130101) H01M 2300/0068 (20130101)
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10256983 — Circuit that includes a physically unclonable function

US 10256983	Bauer et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Todd Bauer (Albuquerque, New Mexico); Jason Hamlet (Albuquerque, New Mexico); Ryan Michael Birmingham (Albuquerque, New Mexico); Lyndon G. Pierson (Albuquerque, New Mexico)
ABSTRACT	Described herein are various technologies pertaining to authentication of integrated circuits by using external factors to affect or modify an output of a physically unclonable function (PUF) circuit. In an example, the output of the PUF circuit in response to a challenge signal can be sensitive to changes in environmental factors. In another example, the output of the PUF circuit can be sensitive to user-selectable configuration parameters of the PUF circuit. In yet another example, the output of the PUF circuit can be modified by additional circuitry external to the PUF circuit based upon one or more selectable or configurable inputs. A PUF-based device authentication system that uses external factors as authentication inputs to affect a challenge response of the device authentication system can enhance authentication capabilities by permitting multi-factor authentication.
FILED	Tuesday, March 22, 2016
APPL NO	15/077488
ART UNIT	2435 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0861 (20130101) H04L 9/3278 (20130101) Original (OR) Class
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National Science Foundation (NSF)

10251566 — Methods and apparatus for determining a central aortic pressure waveform from a peripheral artery pressure waveform

US 10251566	Mukkamala et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Ramakrishna Mukkamala (Okemos, Michigan); Gokul Swamy (East Lansing, Michigan); Nicholas Bari Olivier (Haslett, Michigan)
ASSIGNEE(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S)	Ramakrishna Mukkamala (Okemos, Michigan); Gokul Swamy (East Lansing, Michigan); Nicholas Bari Olivier (Haslett, Michigan)
ABSTRACT	A method is provided for determining a central aortic pressure (AP) wave-form for a subject. The method includes measuring a peripheral artery pressure (PAP) waveform from the subject, employing a distributed model to define a pressure-to-pressure transfer function relating PAP to AP and a pressure-to-flow transfer function relating PAP to a central arterial flow in terms of the same unknown parameters, estimating the unknown parameters by finding the pressure-to-flow transfer function, which when applied to the measured PAP waveform, minimizes the magnitude of the central arterial flow waveform during diastole, and applying the pressure-to-pressure transfer function with the estimated parameters to determine an AP waveform for the subject.
FILED	Wednesday, May 27, 2009
APPL NO	12/993544
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/021 (20130101) Original (OR) Class A61B 5/029 (20130101) A61B 5/02125 (20130101)
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10251780 — 3-coil wireless power transfer system for eye implants

US 10251780	Tai et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California)
INVENTOR(S)	Yu-Chong Tai (Pasadena, California); Yu Zhao (Pasadena, California); Mark S. Humayun (Glendale, California); James D. Weiland (Valencia, California)
ABSTRACT	A three-coil electromagnetic induction power transfer system is disclosed for epiretinal prostheses and other implants. A third, buffer coil is disposed between an external transmitting coil and a receiver coil buried within the body to improve efficiency and robustness to misalignments. One or more of the coils can be manufactured using micromechanical machining techniques to lay out conductors in a ribbon of biocompatible insulator, folding lengths of the insulated conductor traces longitudinally over one another, and then spiraling them into a ring. The traces change axial position in the ring by shifting across fold lines. One or more U-shaped sections on the traces can be folded so that adjacent traces can project opposite one another, lengthening the resulting ribbon that can be wound into a coil.
FILED	Wednesday, June 24, 2015
APPL NO	14/749487
ART UNIT	2859 — Printing/Measuring and Testing
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/007 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0529 (20130101) A61N 1/0543 (20130101) A61N 1/0551 (20130101) A61N 1/3605 (20130101) A61N 1/3787 (20130101) A61N 1/36046 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/00 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/2804 (20130101) H01F 2027/2809 (20130101)
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10251841 — Polymeric depots for localization of agent to biological sites

US 10251841	Grinstaff et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
ASSIGNEE(S)	TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
INVENTOR(S)	Mark W. Grinstaff (Brookline, Massachusetts); Aaron H. Colby (Concord, Massachusetts); Yolonda Colson (Dover, Massachusetts)
ABSTRACT	Provided herein are polymeric particles and compounds and processes that can be used to prepare polymer-based particles and methods of using those particles to localize or concentrate a subsequently delivered agent to an in vivo site.
FILED	Wednesday, October 17, 2012
APPL NO	14/351972
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1641 (20130101) Original (OR) Class A61K 9/5138 (20130101) A61K 31/337 (20130101) A61K 31/352 (20130101) A61K 31/519 (20130101) A61K 47/555 (20170801) A61K 49/0054 (20130101)
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10252239 — Multi-phase oscillatory flow reactor

US 10252239	Abolhasani et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Milad Abolhasani (Raleigh, North Carolina); Connor Wilson Coley (Cambridge, Massachusetts); Klavs F. Jensen (Lexington, Massachusetts)
ABSTRACT	According to some aspects, described herein is an automated droplet-based reactor that utilizes oscillatory motion of a droplet in a tubular reactor under inert atmosphere. In some cases, such a reactor may address current shortcomings of continuous multi-phase flow platforms.
FILED	Friday, August 12, 2016
APPL NO	15/235730
ART UNIT	1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0033 (20130101) Original (OR) Class B01J 19/0093 (20130101) B01J 19/185 (20130101) B01J 2219/00011 (20130101) B01J 2219/0084 (20130101) B01J 2219/0086 (20130101) B01J 2219/0097 (20130101) B01J 2219/00162 (20130101) B01J 2219/00792 (20130101) B01J 2219/00795 (20130101) B01J 2219/00806 (20130101) B01J 2219/00813 (20130101) B01J 2219/00815 (20130101) B01J 2219/00817 (20130101) B01J 2219/00833 (20130101) B01J 2219/00835 (20130101) B01J 2219/00869 (20130101) B01J 2219/00873 (20130101) B01J 2219/00936 (20130101) B01J 2219/00943 (20130101) B01J 2219/00961 (20130101) B01J 2219/00986 (20130101)
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10252251 — Production of organic materials using solid catalysts

US 10252251	Lin et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Board of Regents of the Nevada System of Higher Education, on Behalf of the University of Nevada, Reno (Reno, Nevada)
ASSIGNEE(S)	Board of Regents of the Nevada System of Higher Education, on Behalf of the University of Nevada, Reno (Reno, Nevada)
INVENTOR(S)	Hongfei Lin (Pullman, Washington); Lisha Yang (Reno, Nevada)
ABSTRACT	The present disclosure provides a method for producing organic compounds, such as esters, from an organic feedstock that includes at least one of a biopolymer or a lipid. The method includes heating the feedstock in the presence of a solid catalyst, such as a solid, inorganic Lewis acid catalyst, and reaction medium that includes an alcohol. At least certain ester products have an ester group corresponding to a substituent of the alcohol.
FILED	Friday, August 26, 2016
APPL NO	15/249166
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/0308 (20130101) B01J 29/7049 (20130101) Original (OR) Class B01J 35/002 (20130101) B01J 35/1023 (20130101) B01J 35/1042 (20130101) B01J 35/1047 (20130101) B01J 35/1061 (20130101) Acyclic or Carbocyclic Compounds C07C 67/00 (20130101) C07C 67/00 (20130101) C07C 69/68 (20130101)
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10252270 — Nozzle apparatus and methods for use thereof

US 10252270	Weierstall et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI)
APPLICANT(S)	Uwe Weierstall (Phoenix, Arizona); Dingjie Wang (Tempe, Arizona); John Spence (Tempe, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Uwe Weierstall (Phoenix, Arizona); Dingjie Wang (Tempe, Arizona); John Spence (Tempe, Arizona)
ABSTRACT	Nozzle Assemblies and methods of use for producing a liquid jet are disclosed that may be permit adjustable time delays between mixing of fluids and observation of reactions. An example nozzle assembly includes: a housing having an inlet and an outlet and a first channel defined therebetween, where the housing includes a gas focusing aperture defining the housing outlet; an intermediate tube disposed within the first channel of the housing, where the intermediate tube has an inlet and an outlet and defines a second channel therebetween; and a central tube disposed within the second channel of the intermediate tube, where the central tube has an inlet and an outlet and defines a third channel therebetween, where the central tube outlet is longitudinally spaced apart from the intermediate tube outlet such that the intermediate tube outlet is disposed between the central tube outlet and the gas focusing aperture's inlet.
FILED	Tuesday, September 08, 2015
APPL NO	15/509376
ART UNIT	3752 — Fluid Handling and Dispensing
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0865 (20130101) B01F 3/04007 (20130101) B01F 5/045 (20130101) B01F 13/0062 (20130101) B01F 13/0093 (20130101) B01F 2215/0037 (20130101) B01F 2215/0431 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502776 (20130101) Original (OR) Class B01L 2200/0636 (20130101) B01L 2300/0832 (20130101) B01L 2300/0858 (20130101) B01L 2300/0867 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/32 (20130101)
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10252289 — Nanoparticle coating of surfaces

US 10252289	Hoerr et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Science Foundation (NSF)
APPLICANT(S)	Nanocopoeia, Inc. (St. Paul, Minnesota)
ASSIGNEE(S)	NANOCOPOEIA, INC. (St. Paul, Minnesota)
INVENTOR(S)	Robert A. Hoerr (Shoreview, Minnesota); John V. Carlson (St. Michael, Minnesota)
ABSTRACT	A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
FILED	Friday, August 14, 2015
APPL NO	14/826644
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 2300/41 (20130101) A61L 2300/45 (20130101) A61L 2300/404 (20130101) A61L 2300/416 (20130101) A61L 2300/602 (20130101) A61L 2300/624 (20130101) A61L 2400/12 (20130101) A61L 2420/02 (20130101) A61L 2420/06 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 5/03 (20130101) B05B 5/08 (20130101) B05B 5/025 (20130101) B05B 7/061 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/04 (20130101) B05D 1/06 (20130101) Original (OR) Class B05D 1/34 (20130101) B05D 1/36 (20130101) B05D 7/54 (20130101) B05D 2258/00 (20130101) B05D 2401/32 (20130101) B05D 2451/00 (20130101) B05D 2451/00 (20130101)
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10252466 — Systems and methods of machine vision assisted additive fabrication

US 10252466	Ramos et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Javier E. Ramos (San Juan, Puerto Rico); Pitchaya Sitthi-Amorn (Cambridge, Massachusetts); Wojciech Matusik (Lexington, Massachusetts); Yuwang Wang (Beijing, China PRC)
ABSTRACT	The present application relates generally to systems and methods for using machine vision to provide information on one or more aspects of an additive fabrication device, such as calibration parameters and/or an object formed by the device or in the process of being formed by the device. According to some aspects, a method is provided for calibrating an additive fabrication device. According to some aspects, a method is provided for assessing at least a portion of an object formed using an additive fabrication device. According to some aspects, a method is provided for fabricating a second object in contact with a first object using an additive fabrication device. According to some aspects, an additive fabrication device configured to perform one or more of the above methods may be provided.
FILED	Thursday, March 12, 2015
APPL NO	14/645616
ART UNIT	1747 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) B29C 64/112 (20170801) B29C 64/386 (20170801) Original (OR) Class B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201)
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10252914 — Nanostructured graphene with atomically-smooth edges

US 10252914	Arnold et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S)	Michael Scott Arnold (Middleton, Wisconsin); Padma Gopalan (Madison, Wisconsin); Nathaniel S. Safron (Madison, Wisconsin); Myungwoong Kim (Madison, Wisconsin)
ABSTRACT	Methods of producing layers of patterned graphene with smooth edges are provided. The methods comprise the steps of fabricating a layer of crystalline graphene on a surface, wherein the layer of crystalline graphene has a crystallographically disordered edge, and decreasing the crystallographic disorder of the edge of the layer of crystalline graphene by heating the layer of crystalline graphene on the surface at an elevated temperature in a catalytic environment comprising carbon-containing molecules.
FILED	Thursday, June 16, 2016
APPL NO	15/184036
ART UNIT	1785 — Miscellaneous Articles, Stock Material
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/182 (20170801) Original (OR) Class C01B 32/186 (20170801) C01B 32/194 (20170801) C01B 2204/32 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/734 (20130101) Y10S 977/843 (20130101) Y10S 977/932 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24802 (20150115)
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10253203 — Rough polyelectrolyte complex coatings and methods of forming

US 10253203	Schlenoff
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S)	Joseph B. Schlenoff (Tallahassee, Florida)
ABSTRACT	Articles are provided comprising a substrate and a coating. The coating comprises a polyelectrolyte complex having surface roughness. The polyelectrolyte complex has a thickness of at least 10 micrometers and a roughness of at least 1 micrometer.
FILED	Monday, February 02, 2015
APPL NO	15/115985
ART UNIT	1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/14 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 3/007 (20130101) B05D 5/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1662 (20130101) C09D 5/1681 (20130101) C09D 125/18 (20130101) C09D 147/00 (20130101) Original (OR) Class C09D 201/02 (20130101)
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10253255 — Phosphorescent nanoparticles and their uses in biosensing and bioimaging

US 10253255	Omary et al.
FUNDED BY	Non-Profit Organization (NPO) Robert A. Welch Foundation National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	University of North Texas (Denton, Texas)
ASSIGNEE(S)	UNIVERSITY OF NORTH TEXAS (Denton, Texas)
INVENTOR(S)	Mohammad A. Omary (Denton, Texas); Sreekar Marpu (Denton, Texas)
ABSTRACT	Size-tunable phosphorescent particles may be formed through self-assembly of biocompatible linear polymers, such as chitosan and other linear polymers, that bear positive surface charges, through polyelectrolytic complexation to a polyanionic metal phosphor, such as polyanionic gold(I) phosphor (AuP). The phosphorescent hydrogel nanoparticles and thin films thereof are useful for imaging, sensing of biological molecules, detection of hypoxia, and light-emitting devices. The phosphorescent hydrogel particles can be formed from a variety of linear polymers by physical cross-linking using polyelectrolytic light-emitting species, without the need for the phosphorescent complex to be entrapped in an existing microsphere or nanosphere polymer particle.
FILED	Wednesday, November 30, 2016
APPL NO	15/365031
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) B82Y 20/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 2305/08 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 11/025 (20130101) C09K 11/70 (20130101) C09K 11/87 (20130101) C09K 11/0883 (20130101) Original (OR) Class C09K 2211/188 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/92 (20130101) Y10S 977/774 (20130101) Y10S 977/896 (20130101)
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10253256 — Use of sulfur and selenium compounds as precursors to nanostructured materials

US 10253256	Owen et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Jonathan S. Owen (New York, New York); Mark P. Hendricks (Richland, Washington); Michael P. Campos (New York, New York)
ABSTRACT	The presently disclosed subject matter provides processes for preparing nanocrystals, including processes for preparing core-shell nanocrystals. The presently disclosed subject matter also provides sulfur and selenium compounds as precursors to nanostructured materials. The presently disclosed subject matter also provides nanocrystals having a particular particle size distribution.
FILED	Friday, September 26, 2014
APPL NO	15/024550
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 1/18 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/04 (20130101) C01B 19/007 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 3/12 (20130101) C01G 11/02 (20130101) C01G 21/21 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/04 (20130101) C01P 2004/64 (20130101) Acyclic or Carbocyclic Compounds C07C 335/08 (20130101) C07C 335/16 (20130101) C07C 391/00 (20130101) C07C 2601/14 (20170501) Heterocyclic Compounds C07D 207/34 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/003 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/565 (20130101) C09K 11/582 (20130101) C09K 11/661 (20130101) C09K 11/883 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/95 (20130101) Y10S 977/774 (20130101) Y10S 977/892 (20130101)
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10253287 — In vitro culture model of anisotropic to isotropic transitions

US 10253287	Rivet et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
ASSIGNEE(S)	Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S)	Christopher John Rivet (Grand Blanc, Michigan); Gregory Patrick Desmond (Marshfield, Massachusetts); Jonathan Michael Zuidema (Grand Haven, Michigan); Ryan James Gilbert (Troy, New York)
ABSTRACT	Cell culture devices, and related methods and kits, for modeling isotropic-to-anisotropic cellular transitions are provided. The devices can include a substrate having an isotropic film surface with one or more regions of aligned fibers dispersed thereon.
FILED	Tuesday, August 25, 2015
APPL NO	15/506974
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class C12M 23/20 (20130101) C12M 25/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0622 (20130101)
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10253365 — Type V CRISPR/Cas effector proteins for cleaving ssDNAs and detecting target DNAs

US 10253365	Doudna et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Jennifer A. Doudna (Berkeley, California); Janice S. Chen (Berkeley, California); Lucas Benjamin Harrington (Berkeley, California); Enbo Ma (Moraga, California)
ABSTRACT	Provided are compositions and methods for detecting a target DNA (double stranded or single stranded) in a sample. In some embodiments, a subject method includes: (a) contacting the sample with: (i) a type V CRISPR/Cas effector protein (e.g., a Cas12 protein such as Cas12a, Cas12b, Cas12c, Cas12d, Cas12e); (ii) a guide RNA (comprising a region that binds to the type V CRISPR/Cas effector protein, and a guide sequence that hybridizes with the target DNA); and (iii) a detector DNA that is single stranded (i.e., a “single stranded detector DNA”) and does not hybridize with the guide sequence of the guide RNA; and (b) measuring a detectable signal produced by cleavage (by the type V CRISPR/Cas effector protein) of the single stranded detector DNA. Also provided are compositions and methods for cleaving single stranded DNAs (e.g., non-target ssDNAs), e.g., inside of a cell.
FILED	Wednesday, February 14, 2018
APPL NO	15/897089
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Original (OR) Class
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10254229 — Portable water quality instrument

US 10254229	Peterman et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	OndaVia, Inc. (Hayward, California)
ASSIGNEE(S)	OndaVia, Inc. (Hayward, California)
INVENTOR(S)	Mark C. Peterman (Fremont, California); Merwan Benhabib (San Francisco, California); Samuel Kleinman (Oakland, California)
ABSTRACT	A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.
FILED	Wednesday, March 05, 2014
APPL NO	14/198163
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/12 (20130101) B01L 2200/0652 (20130101) B01L 2300/087 (20130101) B01L 2300/0627 (20130101) B01L 2300/0636 (20130101) B01L 2300/0654 (20130101) B01L 2300/0681 (20130101) B01L 2300/0867 (20130101) B01L 2400/0418 (20130101) B01L 2400/0421 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/18 (20130101) G01J 3/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) G01N 21/65 (20130101) Original (OR) Class G01N 21/658 (20130101) G01N 21/4785 (20130101) G01N 27/44704 (20130101) G01N 27/44791 (20130101) G01N 30/6065 (20130101) G01N 30/6095 (20130101) G01N 33/18 (20130101) G01N 2021/651 (20130101) G01N 2030/0095 (20130101) G01N 2201/13 (20130101) G01N 2201/0221 (20130101)
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10254271 — Controlling translocation through nanopores with fluid walls

US 10254271	Mayer et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Michael Mayer (Ann Arbor, Michigan); Erik Yusko (Ann Arbor, Michigan); Jerry Yang (La Jolla, California)
ABSTRACT	Improved resolution and detection of nanoparticles are achieved when a nanopore connecting liquid compartments in a device running on the Coulter principle is provided with fluid coatings such as lipid walls. Fluid lipid walls are made of a lipid bilayer, and preferably include lipid anchored mobile ligands as part of the lipid bilayer. By varying the nature and concentration of the mobile ligand in the lipid bilayer, multifunctional coatings of lipids are provided.
FILED	Wednesday, May 18, 2016
APPL NO	15/157591
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2563/131 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1209 (20130101) G01N 33/48721 (20130101) Original (OR) Class G01N 2015/0038 (20130101)
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10254287 — Protein fluorescent nanoparticles and methods of synthesis thereof

US 10254287	Kumar et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	University of Connecticut (Farmington, Connecticut)
ASSIGNEE(S)	University of Connecticut (Farmington, Connecticut)
INVENTOR(S)	Challa Vijaya Kumar (Ashford, Connecticut); Bobbi Shanyelle Stromer (Willimantic, Connecticut)
ABSTRACT	Disclosed herein are stable and versatile protein nanoparticles having a range of tunable fluorescent properties. Such nanoparticles may find utility in biological imaging. Methods of synthesis of such nanoparticles are also disclosed.
FILED	Thursday, July 21, 2016
APPL NO	15/216420
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 1/13 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/19 (20130101) G01N 21/6428 (20130101) G01N 25/48 (20130101) G01N 33/84 (20130101) G01N 33/533 (20130101) G01N 33/582 (20130101) G01N 33/587 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 33/54346 (20130101) G01N 2021/6417 (20130101) G01N 2021/6432 (20130101) G01N 2021/6439 (20130101) G01N 2333/92 (20130101) G01N 2333/765 (20130101) G01N 2333/904 (20130101) G01N 2333/908 (20130101) G01N 2333/936 (20130101)
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10254478 — Integrated impedance-matched photonic zero-index metamaterials

US 10254478	Mazur et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	President And Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President And Fellows Of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Eric Mazur (Concord, Massachusetts); Yang Li (Somerville, Massachusetts); Orad Reshef (Ottawa, Canada); Marko Loncar (Cambridge, Massachusetts); Shota Kita (Cambridge, Massachusetts); Philip Alejandro Munoz (Cambridge, Massachusetts); Daryl Vulis (Cambridge, Massachusetts)
ABSTRACT	In one aspect, a composition of matter is disclosed, which comprises a photonic crystal comprising a plurality of 2D or 3D periodically repeating structures, where the structures are configured and arranged relative to one another such that the photonic crystal exhibits a Dirac cone at the center of the Brillouin zone of its reciprocal lattice, e.g., at one frequency in the optical regime. In some embodiments, the structures are formed of a dielectric material. In another aspect, a photonic structure is disclosed, which comprises a substrate, a plurality of periodically repeating cavities formed in said substrate, where the cavities are sized and arranged relative to one another such that said photonic structure exhibits a substantially vanishing refractive index (preferably a zero refractive index) for at least one wavelength of electromagnetic radiation propagating through said photonic structure, for example, for at least one wavelength of the electromagnetic radiation in a range of about 400 nm to about 100 microns.
FILED	Friday, July 29, 2016
APPL NO	15/223680
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) G02B 1/007 (20130101) G02B 6/136 (20130101) G02B 6/1225 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/105 (20130101) H01S 5/183 (20130101)
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10254499 — Additive manufacturing of active devices using dielectric, conductive and magnetic materials

US 10254499	Cohen et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Southern Methodist University (Dallas, Texas)
ASSIGNEE(S)	Southern Methodist University (Dallas, Texas)
INVENTOR(S)	Adam Cohen (Dallas, Texas); Paul Samuel Krueger (Plano, Texas); Matt Saari (Dallas, Texas); Edmond Richer (Richardson, Texas); Bryan Cox (Marion, Arkansas); Bin Xia (Dallas, Texas); Collin Gabriel Clay (Houston, Texas)
ABSTRACT	The present disclosure relates to a process, system and apparatus for multi-material additive manufacturing process comprising: extruding an extrudable material through a nozzle capable of moving along one or more axis and concurrently extruding one or more filaments, wherein the filament is embedded in, on or about the extrudable material from the nozzle.
FILED	Friday, August 04, 2017
APPL NO	15/669263
ART UNIT	2874 — Optics
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/0056 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 64/209 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201) Optical Elements, Systems, or Apparatus G02B 6/4463 (20130101) Original (OR) Class Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/022 (20130101) H01R 4/024 (20130101)
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10256085 — Zero voltage mass spectrometry probes and systems

US 10256085	Cooks et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Robert Graham Cooks (West Lafayette, Indiana); Michael Stanley Wleklinski (Indianapolis, Indiana); Soumabha Bag (West Lafayette, Indiana); Yafeng Li (Beijing, China PRC)
ABSTRACT	The invention generally relates to zero volt mass spectrometry probes and systems. In certain embodiments, the invention provides a system including a mass spectrometry probe including a porous material, and a mass spectrometer (bench-top or miniature mass spectrometer). The system operates without an application of voltage to the probe. In certain embodiments, the probe is oriented such that a distal end faces an inlet of the mass spectrometer. In other embodiments, the distal end of the probe is 5 mm or less from an inlet of the mass spectrometer.
FILED	Thursday, September 07, 2017
APPL NO	15/697560
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/0013 (20130101) H01J 49/0436 (20130101) Original (OR) Class
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10256362 — Flexible silicon infrared emitter

US 10256362	Augusto et al.
FUNDED BY	Department of Defense (DOD) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Andre Filipe Rodrigues Augusto (Tempe, Arizona); Stanislau Herasimenka (Tempe, Arizona); Stuart Bowden (Tempe, Arizona)
ABSTRACT	An apparatus includes a flexible silicon (Si) substrate, such as a crystalline n-type substrate, and a heterostructure structure formed on the silicon substrate. The heterojunction structure includes a first layered structured deposited on a first side of the silicon substrate. The first layered structured includes a first amorphous intrinsic silicon layer, an amorphous n-type or p-type silicon layer, and a transparent conductive layer. The second layered structure includes a second amorphous intrinsic silicon layer, an amorphous p-type or n-type silicon layer, and a transparent conductive layer. The heterostructure structure is configured to operate as a photovoltaic cell and an infrared light emitting diode.
FILED	Monday, July 31, 2017
APPL NO	15/665240
ART UNIT	2893 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/042 (20130101) H01L 31/125 (20130101) Original (OR) Class H01L 31/202 (20130101) H01L 31/0216 (20130101) H01L 31/0504 (20130101) H01L 31/0547 (20141201) H01L 31/0747 (20130101) H01L 31/1868 (20130101) H01L 31/1884 (20130101) H01L 31/02008 (20130101) H01L 31/03762 (20130101) H01L 31/022475 (20130101) H01L 31/035281 (20130101) H01L 33/22 (20130101) H01L 33/24 (20130101) H01L 33/34 (20130101) H01L 33/42 (20130101) H01L 33/46 (20130101) H01L 33/0058 (20130101) H01L 33/0095 (20130101) H01L 2933/0016 (20130101) H01L 2933/0025 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/38 (20141201)
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10256407 — Organic thin film transistors

US 10256407	Jurchescu et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	WAKE FOREST UNIVERSITY (Winston-Salem, North Carolina)
ASSIGNEE(S)	Wake Forest University (Winston-Salem, North Carolina)
INVENTOR(S)	Oana Diana Jurchescu (Winston-Salem, North Carolina); Peter James Diemer (Mocksville, North Carolina)
ABSTRACT	In one aspect, organic thin film transistors are described herein. In some embodiments, an organic thin film transistor comprises a source terminal, a drain terminal and a gate terminal; a dielectric layer positioned between the gate terminal and the source and drain terminals; and a vibrationally-assisted drop-cast organic film comprising small molecule semiconductor in electrical communication with the source terminal and drain terminal, wherein the transistor has a carrier mobility (μ_eff) of at least about 1 cm²/V·s.
FILED	Monday, January 22, 2018
APPL NO	15/876596
ART UNIT	2892 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0001 (20130101) H01L 51/0003 (20130101) Original (OR) Class H01L 51/0026 (20130101) H01L 51/42 (20130101) H01L 51/442 (20130101) H01L 51/0512 (20130101) H01L 51/0541 (20130101) H01L 51/0545 (20130101) H01L 51/4253 (20130101) H01L 2251/301 (20130101) H01L 2251/303 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101)
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10256864 — Full-duplex self-interference cancellation systems

US 10256864	Eltawil et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Ahmed Mohamed Eltawil (Oakland, California); Elsayed A. Ahmed (Oakland, California)
ABSTRACT	Embodiments of full-duplex self-interference cancellation systems are described. In one embodiment, a full-duplex transceiver includes a digital signal processor that processes digital signals, a transmit chain that receives a first digital baseband signal from the digital signal processor and converts it to a first RF signal, a receive chain that receives a second RF signal and converts the second RF signal to a second digital baseband signal, and an auxiliary receive chain that receives a portion of the first RF signal and converts it to an auxiliary digital baseband signal. The transceiver may further include a self-interference canceller that applies a channel transfer function to the auxiliary digital baseband signal to generate a cancellation signal and subtracts the cancellation signal from the second digital baseband signal to cancel self-interference at the transceiver. The suppression of self-interference in the transceiver assists the transceiver to achieve higher efficiency in full-duplex communications.
FILED	Monday, February 27, 2017
APPL NO	15/443430
ART UNIT	2464 — Multiplex and VoIP
CURRENT CPC	Transmission H04B 1/44 (20130101) H04B 1/123 (20130101) H04B 1/525 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 5/1461 (20130101)
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10256939 — Scheduled light path switching in optical networks and automatic assessment of traffic impairments that would result from adding or deleting a channel in a wavelength-division multiplexed optical communication network

US 10256939	Zhang et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Lei Zhang (Lexington, Massachusetts); Vincent W. S. Chan (Lincoln, Massachusetts)
ABSTRACT	A single-wavelength light path is selected between a source access node and a destination access node of a wavelength-division multiplexed optical network, including selecting an illuminated wavelength of the light path and selecting a start time and duration for a data transfer that would not interfere with other data transfers. If no start time/wavelength combination is available with duration sufficient to transport the data, an additional wavelength is automatically selected, based on modeling, that would not impair traffic being carried by other wavelengths in the network, and without a time-consuming manual process of the prior art. The scheduling process may include selecting a set of optical fibers, a wavelength, a start time and an end time to transport proposed traffic. A novel scheduler avoids checking every possible start time, thereby saving significant processing time. The scheduler schedules single-wavelength light paths, rather than relying on complex wavelength shifting schemes.
FILED	Monday, July 30, 2018
APPL NO	16/048961
ART UNIT	2636 — Optical Communications
CURRENT CPC	Multiplex Communication H04J 14/0212 (20130101) H04J 14/0257 (20130101) H04J 14/0271 (20130101) Original (OR) Class
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10257100 — Enabling resilient microgrid through ultra-fast programmable network

US 10257100	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	University of Connecticut (Farmington, Connecticut)
ASSIGNEE(S)	University of Conneticut (Farmington, Connecticut)
INVENTOR(S)	Peng Zhang (Storrs Mansfield, Connecticut); Bing Wang (Storrs Mansfield, Connecticut); Peter B. Luh (Storrs Mansfield, Connecticut); Lingyu Ren (Storrs Mansfield, Connecticut); Yanyuan Qin (Storrs Mansfield, Connecticut)
ABSTRACT	Systems and methods for integrating ultra-fast programmable networks in microgrid are disclosed to provide flexible and easy-to-manage communication solutions, thus enabling resilient microgrid operations in face of various cyber and physical disturbances. The system is configured to establish a novel software-defined networking (SDN) based communication architecture which abstracts the network infrastructure from the upper-level applications to significantly expedite the development of microgrid applications, develop three functions of the SDN controller for microgrid emergency operations, including time delay guarantee, failover reconfiguration and rate limit and create a hardware-in-the-loop cyber-physical platform for evaluating and validating the performance of the presented architecture and control techniques.
FILED	Friday, April 28, 2017
APPL NO	15/581601
ART UNIT	2461 — Multiplex and VoIP
CURRENT CPC	Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 13/0086 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/08 (20130101) H04L 45/28 (20130101) H04L 45/42 (20130101) H04L 45/64 (20130101) H04L 45/121 (20130101) H04L 47/24 (20130101) H04L 47/25 (20130101) Original (OR) Class H04L 47/41 (20130101)
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National Aeronautics and Space Administration (NASA)

10251565 — Multi-channel vitals device

US 10251565	Chan et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	DNA Medicine Institute, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	DNA Medicine Institute, Inc. (Cambridge, Massachusetts)
INVENTOR(S)	Eugene Y. Chan (Boston, Massachusetts); Dexter Eames (Cambridge, Massachusetts); Marcus Atkin (Derby, United Kingdom)
ABSTRACT	An integrated vitals device capable of acquiring multiple data streams, allowing for comprehensive measurement of whole health status using a single, compact device. This allows for simplification of traditional healthcare delivery where multiple devices are required for acquisition of vital signs. A sensor stack up, occupying the approximate physical footprint and volume allows this approach to be possible. This application describes how these simultaneous vitals data streams can be acquired using an integrated device with small mass and volume.
FILED	Saturday, April 30, 2016
APPL NO	15/143560
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/0402 (20130101) A61B 5/0816 (20130101) A61B 5/02055 (20130101) Original (OR) Class A61B 5/02438 (20130101) A61B 5/6833 (20130101) A61B 5/14551 (20130101) A61B 2562/06 (20130101) A61B 2562/0238 (20130101) A61B 2562/0271 (20130101)
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10252792 — Flow disruption devices for the reduction of high lift system noise

US 10252792	Hutcheson et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S)	Florence V. Hutcheson (Virginia Beach, Virginia); Thomas F. Brooks (The Villages, Florida)
ABSTRACT	Various embodiments provide systems and methods for noise reduction for lift-augmentation wing-sections (e.g., flaps, slats, elevons, etc.) by the use of flow disruption devices placed upstream of vortex generation locations. The flow disruption devices may reduce the noise radiating from side edges of lift-augmentation control wing sections. An embodiment flow disruption device may include a body configured to protrude into a flow over a vehicle's surface, wherein the body is coupled to the vehicle upstream of a side edge of a structure of the vehicle such that a wake produced by the body introduces unsteadiness and a flow velocity deficit in a vortex formation region of the side edge of the structure.
FILED	Friday, April 15, 2016
APPL NO	15/130236
ART UNIT	3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Aeroplanes; Helicopters B64C 9/12 (20130101) B64C 23/06 (20130101) Original (OR) Class B64C 2220/00 (20130101) B64C 2230/14 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/162 (20130101) Y02T 50/166 (20130101)
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10253424 — Porous particles and methods of making thereof

US 10253424	Ferrari et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Board of Regents of the University of Texas System (Austin, Texas); The Ohio State University Research Foundation (Columbus, Ohio)
ASSIGNEE(S)	BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (Columbus, Ohio)
INVENTOR(S)	Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugar Land, Texas); Ming-Cheng Cheng (Pearland, Texas)
ABSTRACT	Provided is a particle that includes a first porous region and a second porous region that differs from the first porous region. Also provided is a particle that has a wet etched porous region and that does have a nucleation layer associated with wet etching. Methods of making porous particles are also provided.
FILED	Tuesday, November 11, 2014
APPL NO	14/538065
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 8/25 (20130101) A61K 9/141 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/02 (20130101) C01B 33/021 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/16 (20130101) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/12 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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10254164 — Compact mapping spectrometer

US 10254164	Zollars et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	NANOHMICS, INC. (Austin, Texas)
ASSIGNEE(S)	NANOMMICS, INC. (Austin, Texas)
INVENTOR(S)	Byron G. Zollars (Georgetown, Texas); Chris W. Mann (Austin, Texas); Gabriel Elpers (Houston, Texas)
ABSTRACT	A compact, mapping spectrometer and various embodiments of the spectrometer are described. Methods for performing high-resolution spectroscopic, spatial, and polarimetric analyses of electromagnetic radiation across the complete electromagnetic spectrum, using spectrometer embodiments of the invention, are also described. The spectrometer and associated methods are useful for producing spectral and hyperspectral images associated with the incoming radiation and for identifying other information about electromagnetic radiation of interest.
FILED	Thursday, April 14, 2016
APPL NO	15/099085
ART UNIT	2877 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0205 (20130101) G01J 3/0216 (20130101) G01J 3/2803 (20130101) Original (OR) Class G01J 3/2823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) G01N 15/1463 (20130101) G01N 2015/1006 (20130101)
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10254325 — Piezoelectric field disturbance sensing system and method

US 10254325	Jensen
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Scott Jensen (Carriere, Mississippi)
ABSTRACT	A piezoelectric field disturbance sensing system includes a piezoelectric element for generating mechanical energy when electrically excited and for generating electrical energy when mechanically deformed. A mass is coupled to the piezoelectric element. A signal generator is coupled to the piezoelectric element for applying electrical energy thereto for a fixed period of time. As a result, the piezoelectric element undergoes mechanical deformation and the mass reverberates in response to such mechanical deformation. A charge monitor is coupled to the piezoelectric element for monitoring electrical energy generated thereby during a time period subsequent to the fixed period of time.
FILED	Tuesday, April 21, 2015
APPL NO	14/691623
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 29/22 (20130101) Original (OR) Class
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10254405 — Hyperfine interpolated range finding for CW lidar, radar, and sonar using repeating waveforms and fourier transform reordering

US 10254405	Campbell et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S)	Joel F. Campbell (Poquoson, Virginia); Bing Lin (Yorktown, Virginia); Amin R. Nehrir (Yorktown, Virginia)
ABSTRACT	Systems, methods, and devices may enhance the apparent sample rate of data collected using Nyquist sampling from a system, such as Continuous Wave (CW) Light detection and ranging (“Lidar”), Radio detection and ranging (“Radar”), or Sound Navigation and Ranging (“Sonar”), that has been modulated with a repeating waveform, such as linear swept frequency, by reordering of the data in the frequency domain. The enhancement of the apparent sample rate may result in a highly interpolated range profile where the data resolution may be enhanced by a factor equal to the number of repeats in the signal being processed, and may result in a highly detained range measurement with a high precision. The various embodiments may combine data from multiple modulation repeats into a single highly interpolated pulse, which may result in a real-time finer range measurement from CW Lidar, Radar, or Sonar systems.
FILED	Tuesday, August 04, 2015
APPL NO	14/817805
ART UNIT	2865 — Printing/Measuring and Testing
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/352 (20130101) G01S 7/534 (20130101) G01S 7/4865 (20130101) G01S 7/4915 (20130101) G01S 17/32 (20130101) Original (OR) Class G01S 2007/356 (20130101)
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10255382 — Method for forming component-level radiation shield optimized for environmental radiation characteristics and design critera

US 10255382	Lauenstein et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S)	Jean-Marie Lauenstein (Laurel, Maryland); Steven J. Kenyon (Hanover, Maryland); Raymond L. Ladbury (Mt. Airy, Maryland); Thomas Jordan (Gaithersburg, Maryland)
ABSTRACT	A method for forming an optimized radiation shield design for a component including providing a computer system programmed to generate data files that define a component radiation shield having an optimized design based on pre-stored data defining particular radiation characteristics and user-provided data defining radiation shield design criteria. Radiation shield design criteria are inputted into the computer system which processes the inputted radiation shield design criteria and the pre-stored data defining particular radiation characteristics in order to generate data files defining an optimized design for a component radiation shield. The generated data files defining the optimized design for a component radiation shield are provided to a metallic three-dimensional printing system. The three-dimensional printing system is then activated to form a component radiation shield using a predetermined metal powder and the generated data files that define the optimized component radiation shield design. The formed component radiation shield is then attached to the component or the circuit board.
FILED	Thursday, August 24, 2017
APPL NO	15/685556
ART UNIT	2116 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/10 (20170801) Electric Digital Data Processing G06F 17/50 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 9/0073 (20130101)
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10256202 — Durable bond pad structure for electrical connection to extreme environment microelectronic integrated circuits

US 10256202	Spry et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	David J. Spry (Medina, Ohio); Dorothy Lukco (Sagamore Hills, Ohio); Philip G. Neudeck (Olmsted Township, Ohio); Carl W. Chang (Westlake, Ohio); Liangyu Chen (Cleveland, Ohio); Roger D. Meredith (Cleveland, Ohio); Kelley M. Moses (Cleveland, Ohio); Charles A. Blaha (North Royalton, Ohio); Jose M. Gonzalez (Fort Walton Beach, Florida); Glenn M. Beheim (Hiram, Ohio); Kimala L. Laster (Cleveland, Ohio)
ABSTRACT	A durable bond pad structure is described that facilitates highly durable electrical connections to semiconductor microelectronics chips (e.g., silicon carbide (SiC) chips) to enable prolonged operation over very extreme temperature ranges.
FILED	Thursday, January 25, 2018
APPL NO	15/880139
ART UNIT	2811 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/5226 (20130101) H01L 23/53257 (20130101) H01L 24/05 (20130101) Original (OR) Class H01L 2224/05009 (20130101) H01L 2224/05015 (20130101) H01L 2224/05084 (20130101) H01L 2224/05169 (20130101) H01L 2224/05178 (20130101) H01L 2224/05181 (20130101) H01L 2224/05187 (20130101) H01L 2224/05193 (20130101) H01L 2224/05644 (20130101) H01L 2924/0475 (20130101) H01L 2924/3512 (20130101) H01L 2924/04642 (20130101) H01L 2924/10272 (20130101)
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10256305 — High mobility transport layer structures for rhombohedral Si/Ge/SiGe devices

US 10256305	Choi et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S)	Sang Hyouk Choi (Poquoson, Virginia); Yeonjoon Park (Yorktown, Virginia); Glen C. King (Williamsburg, Virginia); Hyun-Jung Kim (Poquoson, Virginia); Kunik Lee (Troy, Michigan)
ABSTRACT	An electronic device includes a trigonal crystal substrate defining a (0001) C-plane. The substrate may comprise Sapphire or other suitable material. A plurality of rhombohedrally aligned SiGe (111)-oriented crystals are disposed on the (0001) C-plane of the crystal substrate. A first region of material is disposed on the rhombohedrally aligned SiGe layer. The first region comprises an intrinsic or doped Si, Ge, or SiGe layer. The first region can be layered between two secondary regions comprising n+doped SiGe or n+doped Ge, whereby the first region collects electrons from the two secondary regions.
FILED	Friday, March 03, 2017
APPL NO	15/449449
ART UNIT	2822 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0242 (20130101) H01L 21/0245 (20130101) H01L 21/02433 (20130101) H01L 21/02516 (20130101) H01L 21/02532 (20130101) H01L 21/02584 (20130101) H01L 29/045 (20130101) H01L 29/155 (20130101) H01L 29/157 (20130101) Original (OR) Class H01L 29/165 (20130101) H01L 29/7782 (20130101) H01L 31/0336 (20130101) H01L 31/03682 (20130101) H01L 31/035236 (20130101) H01L 35/22 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/546 (20130101)
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10256530 — Deployable reflector

US 10256530	Freebury et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Jet Propulsion Laboratory (JPL) Federally Funded Research and Development Center (FFRDC) Operated by California Institute of Technology (CALTECH) at Pasadena, CA NASA Shared Services Center (NSSC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	TENDEG LLC (Louisville, Colorado)
ASSIGNEE(S)	Tendeg LLC (Louisville, Colorado)
INVENTOR(S)	Gregg E. Freebury (Louisville, Colorado); Neal J Beidleman (Aspen, Colorado)
ABSTRACT	A reflector assembly including a truss engaging the first net at a first plurality of points along the first net perimeter edge and engaging a second net at a second plurality of points along the second net perimeter edge. A truss deployment assembly moves the truss between a truss stowed condition and a truss deployed condition, the truss in the truss deployed condition tensioning said first net or said second net to maintain a substantially flat or parabolic net outer surface. A reflector disposed at the first net sends or receives remote data.
FILED	Wednesday, December 21, 2016
APPL NO	15/387437
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/288 (20130101) Original (OR) Class H01Q 15/161 (20130101)
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Small Business Administration (SBA)

10251878 — Polysubunit opioid prodrugs resistant to overdose and abuse

US 10251878	Jenkins
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Elysium Therapeutics, Inc. (San Ramon, California)
ASSIGNEE(S)	Elysium Therapeutics, Inc. (Danville, California)
INVENTOR(S)	Thomas E. Jenkins (Half Moon Bay, California)
ABSTRACT	The invention provides compositions and methods for the treatment or prevention of pain. The invention provides constructs whereby hydrolysis of the construct by a specified gastrointestinal enzyme directly, or indirectly, releases an opioid when taken orally as prescribed. The gastrointestinal enzyme mediated release of opioid from constructs of the invention is designed to be attenuated in vivo via a saturation or inhibition mechanism when overdoses are ingested. The invention further provides constructs that are highly resistant to oral overdose, chemical tampering, and abuse via non-oral routes of administration.
FILED	Tuesday, August 22, 2017
APPL NO	15/683356
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) Original (OR) Class A61K 47/55 (20170801) A61K 47/61 (20170801) A61K 47/64 (20170801)
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10252266 — Microfluidic siphoning array for nucleic acid quantification

US 10252266	Hung et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) NIH Office of the Director (NIHOD) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Combinati Incorporated (Palo Alto, California)
ASSIGNEE(S)	COMBINATI INCORPORATED (Palo Alto, California)
INVENTOR(S)	Ju-Sung Hung (Palo Alto, California); Andrew Zayac (San Leandro, California); Megan Dueck (Brisbane, California)
ABSTRACT	In some aspects, the present disclose provides methods for amplifying and quantifying nucleic acids. Methods for amplifying and quantifying nucleic acids comprise isolating a sample comprising nucleic acid molecules into a plurality of microchambers, performing a polymerase chain reaction on the plurality of microchambers, and analyzing the results of the polymerase chain reaction. In some aspects, the present disclosure provides devices consistent with the methods herein.
FILED	Tuesday, July 03, 2018
APPL NO	16/026827
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 7/52 (20130101) B01L 2200/0605 (20130101) B01L 2300/18 (20130101) B01L 2300/0609 (20130101) B01L 2300/0851 (20130101) B01L 2300/0864 (20130101) B01L 2400/049 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 2563/159 (20130101) C12Q 2565/629 (20130101)
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10253357 — Colorimetric detection of nucleic acid amplification

US 10253357	Mitra et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Diassess Inc. (Emeryville, California)
ASSIGNEE(S)	DIASSESS INC. (Emeryville, California)
INVENTOR(S)	Debkishore Mitra (Berkeley, California); Ivan Krastev Dimov (Union City, California); John Robert Waldeisen (Berkeley, California)
ABSTRACT	Colorimetry is used to detect amplification reaction products. A sample is contacted with a reaction mix under conditions such that an amplification reaction occurs and produces an amplification reaction product if the sample contains a target nucleic acid template molecule. The reaction mix includes an enzyme for catalyzing the amplification reaction, and at least one halochromic agent. If the target nucleic acid template molecule is present, the amplification reaction changes the starting pH of the reaction mix to cause a detectable colorimetric change of the halochromic agent, thereby indicating the presence of the target nucleic acid. If the target nucleic acid template molecule is not present, the amplification reaction does not generate an adequate number of protons to sufficiently change the starting pH of the reaction mix to cause a detectable colorimetric change of the halochromic agent, thereby indicating that the amplification reaction product has not been produced.
FILED	Friday, April 24, 2015
APPL NO	15/306240
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) Original (OR) Class C12Q 1/6846 (20130101) C12Q 1/6846 (20130101) C12Q 2527/119 (20130101) C12Q 2527/125 (20130101) C12Q 2563/173 (20130101)
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10256530 — Deployable reflector

US 10256530	Freebury et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Jet Propulsion Laboratory (JPL) Federally Funded Research and Development Center (FFRDC) Operated by California Institute of Technology (CALTECH) at Pasadena, CA NASA Shared Services Center (NSSC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	TENDEG LLC (Louisville, Colorado)
ASSIGNEE(S)	Tendeg LLC (Louisville, Colorado)
INVENTOR(S)	Gregg E. Freebury (Louisville, Colorado); Neal J Beidleman (Aspen, Colorado)
ABSTRACT	A reflector assembly including a truss engaging the first net at a first plurality of points along the first net perimeter edge and engaging a second net at a second plurality of points along the second net perimeter edge. A truss deployment assembly moves the truss between a truss stowed condition and a truss deployed condition, the truss in the truss deployed condition tensioning said first net or said second net to maintain a substantially flat or parabolic net outer surface. A reflector disposed at the first net sends or receives remote data.
FILED	Wednesday, December 21, 2016
APPL NO	15/387437
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/288 (20130101) Original (OR) Class H01Q 15/161 (20130101)
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Department of Agriculture (USDA)

10253324 — Genetically altered alfalfa producing clovamide and/or related hydroxycinnamoyl amides

US 10253324	Sullivan
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Michael L Sullivan (Madison, Wisconsin)
ABSTRACT	Two novel cDNAs for two different genes, HDT1 and HDT2, are isolated from red clover and sequenced. Both HDT1 and HDT2 encode hydroxycinnamoyl-CoA:L-DOPA/tyrosine hydroxycinnamoyl transferase (HDT) which enzymatically produces clovamide and/or related hydroxycinnamoyl amides. Clovamide and related hydroxycinnamoyl amides reduce post-harvest protein degradation. Genetically altered alfalfa plants containing an expression cassette containing a cDNA encoding HDT1 or HDT2 are generated. These genetically altered alfalfa plants produce hydroxycinnamoyl-CoA:L-DOPA/tyrosine hydroxycinnamoyl transferase, which in turn produces clovamide and/or related hydroxycinnamoyl amides.
FILED	Friday, September 23, 2016
APPL NO	15/274050
ART UNIT	1663 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1029 (20130101) C12N 15/8243 (20130101) Original (OR) Class C12N 15/8251 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 203/01 (20130101)
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10253326 — Mutant sorghum bicolor having enhanced seed yield

US 10253326	Xin et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Cold Spring Harbor Laboratory (Cold Spring Harbor, New York)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Cold Spring Harbor Laboratory (Cold Spring Harbor, New York)
INVENTOR(S)	Zhanguo Xin (Lubbock, Texas); Gloria B. Burow (Lubbock, Texas); Chad M Hayes (Lubbock, Texas); John J. Burke (Lubbock, Texas); Doreen Ware (Melville, New York); Yinping Jiao (Cold Spring Harbor, New York)
ABSTRACT	Genetically altered sorghum plants expressing the multi-seeded #2 phenotype contain one of two genomic alterations in the Sb06g018040 gene which result in reduced activity of the encoded protein, a class II 13-lipoxygenase. This phenotype and genotype are referred to as msd2. These alterations result in increased number of seeds and seed weight, thus increasing the yield of the genetically altered plant. These alterations can be generated in the ortholog genes in maize (TS1), rice, barley, and other monocot plants, generating the MSD2 phenotype. The seeds of one particular MSD2 Sorghum bicolor has been deposited with ATCC and assigned Accession Number PTA-121634.
FILED	Thursday, March 31, 2016
APPL NO	15/086992
ART UNIT	1662 — Plants
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0069 (20130101) C12N 15/827 (20130101) C12N 15/8247 (20130101) C12N 15/8261 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) C12Q 2600/13 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 113/11012 (20130101)
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Office of the Director of National Intelligence (ODNI)

10255548 — Method and apparatus for modeling probability matching human subjects in n-arm bandit tasks

US 10255548	Chelian et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Inbound, Controlled, Air-Releasable, Unrecoverable Systems (ICARUS) Office of the Director of National Intelligence (ODNI) Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Suhas E. Chelian (San Jose, California); Rajan Bhattacharyya (Sherman Oaks, California)
ABSTRACT	Described is a system for modeling probability matching in human subjects. Features related to probability matching are extracted from a set of human subject responses from behavioral tasks. Neural network model instances are trained on the set of features, resulting in a set of trained neural network model instances. A set of model parameters are derived from the set of trained neural network instances, and the set of derived model parameters are used to emulate human performance on novel data.
FILED	Thursday, November 05, 2015
APPL NO	14/933414
ART UNIT	2121 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0472 (20130101) Original (OR) Class
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10256106 — Sacrificial shorting straps for superconducting qubits

US 10256106	Chang et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Office of the Director of National Intelligence (ODNI) Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Josephine B. Chang (Bedford Hills, New York); Douglas T. McClure, III (Rye, New York)
ABSTRACT	A technique relates to protecting a tunnel junction. A first electrode paddle and a second electrode paddle are on a substrate. The first and second electrode paddles oppose one another. A sacrificial shorting strap is formed on the substrate. The sacrificial shorting strap connects the first electrode paddle and the second electrode paddle; The tunnel junction is formed connecting the first electrode paddle and the second electrode paddle, after forming the sacrificial shorting strap. The substrate is mounted on a portion of a quantum cavity. The portion of the quantum cavity is placed in a vacuum chamber. The sacrificial shorting strap is etched away in the vacuum chamber while the substrate is mounted to the portion of the quantum cavity, such that the sacrificial shorting strap no longer connects the first and second electrode paddles. The tunnel junction has been protected from electrostatic discharge by the sacrificial shorting strap.
FILED	Friday, February 02, 2018
APPL NO	15/887297
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/3065 (20130101) Original (OR) Class H01L 29/66977 (20130101) H01L 39/025 (20130101) H01L 39/223 (20130101) H01L 39/2493 (20130101)
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Department of Homeland Security (DHS)

10254170 — Contrast phantoms and uses thereof for active millimeter wave imaging systems

US 10254170	Barber
FUNDED BY	Department of Homeland Security (DHS)
APPLICANT(S)	The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S)	Jeffrey Brian Barber (Vineland, New Jersey)
ABSTRACT	The present disclosure is directed to a contrast phantom including: at least three regions including: a first region with a first reflection coefficient; a second region with a second reflection coefficient; and a third region with a third reflection coefficient, wherein at least one of the regions includes an electrically conductive material selected from a semiconductive oxide deposited onto a substrate and/or an electrically conductive polymer, wherein the first reflection coefficient, the second reflection coefficient and the third reflection coefficient are increasing or decreasing in value in discrete steps, and wherein the electrically conductive material includes a thickness of about 200 μm. Methods of using the present contrast phantom are also described.
FILED	Wednesday, August 08, 2018
APPL NO	16/058053
ART UNIT	2884 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/522 (20130101) Original (OR) Class G01J 2005/0077 (20130101)
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Department of Transportation (USDOT)

10256631 — Systems and methods for random-access power management using packetization

US 10256631	Frolik et al.
FUNDED BY	Department of Transportation (USDOT)
APPLICANT(S)	University of Vermont and State Agricultural College (Burlington, Vermont)
ASSIGNEE(S)	University of Vemont and State Agricultural College (Burlington, Vermont)
INVENTOR(S)	Jeff Frolik (Essex Junction, Vermont); Paul Hines (Burlngton, Vermont)
ABSTRACT	Systems and methods for distributing electric energy in discrete power packets of finite duration are presented. Systems may include an aggregator for providing power packets to one or more nodes. An aggregator may receive requests for power packets from nodes. In other embodiments, an aggregator may transmit status broadcasts and nodes may receive power packets based on the status broadcasts.
FILED	Saturday, March 01, 2014
APPL NO	14/772650
ART UNIT	2116 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/14 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 12/6418 (20130101)
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Department of Veterans Affairs (DVA)

10255466 — Methods for organizing the disinfection of one or more items contaminated with biological agents

US 10255466	Jinadatha
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Chetan Jinadatha (Temple, Texas)
ABSTRACT	The invention provides method for organizing the disinfection of one or more items contaminated with biological agent(s) comprising (a) attaching a radio-frequency ID (RFID) tag to an item(s) to be disinfected; exposing the item(s) of (a) to a disinfecting means for a period sufficient to disinfect the item; and (c) obtaining a signal from the tagged item when disinfection is complete thereby organizing the disinfection of one or more items.
FILED	Thursday, August 01, 2013
APPL NO	14/419032
ART UNIT	2632 — Digital Communications
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/24 (20130101) A61L 2/208 (20130101) A61L 2202/14 (20130101) A61L 2202/25 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10118 (20130101) Original (OR) Class G06K 7/10415 (20130101) G06K 7/10475 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/22 (20130101) Technologies for Adaptation to Climate Change Y02A 90/22 (20180101) Y02A 90/26 (20180101)
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Department of the Treasury (TREASURY)

10252563 — Optical products, masters for fabricating optical products, and methods for manufacturing masters and optical products

US 10252563	Rich et al.
FUNDED BY	Department of the Treasury (TREASURY) Bureau of Engraving and Printing (BEP)
APPLICANT(S)	Wavefront Technology, Inc. (Paramount, California)
ASSIGNEE(S)	WAVEFRONT TECHNOLOGY, INC. (Paramount, California)
INVENTOR(S)	Christopher Chapman Rich (Rancho Palos Verdes, California); Joel Mikael Petersen (Valley Village, California); John Michael Tamkin (Pasadena, California); Roger Winston Phillips (Santa Rosa, California); Phillip Christopher Harvey (Long Beach, California)
ABSTRACT	An optical product can reproduce a first 3D image of at least part of a first 3D object and a second 3D image of at least part of a second 3D object. The optical product comprises a surface configured, when illuminated, to reproduce by reflected or transmitted light, the first 3D image without reproducing the second 3D image at a first angle of view, and the second 3D image without reproducing the first 3D image at a second angle of view. Each portion of first portions can correspond to a point on a surface of the first 3D object, and comprise first non-holographic features configured to produce at least part of the first 3D image. Each portion of second portions can correspond to a point on a surface of the second 3D object, and comprise second non-holographic features configured to produce at least part of the second 3D image.
FILED	Tuesday, July 12, 2016
APPL NO	15/208551
ART UNIT	2872 — Optics
CURRENT CPC	Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/21 (20141001) B42D 25/29 (20141001) B42D 25/324 (20141001) B42D 25/351 (20141001) B42D 25/355 (20141001) B42D 25/373 (20141001) B42D 25/378 (20141001) Original (OR) Class B42D 25/425 (20141001) Optical Elements, Systems, or Apparatus G02B 5/18 (20130101) G02B 27/22 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Non-Profit Organization (NPO)

10253255 — Phosphorescent nanoparticles and their uses in biosensing and bioimaging

US 10253255	Omary et al.
FUNDED BY	Non-Profit Organization (NPO) Robert A. Welch Foundation National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	University of North Texas (Denton, Texas)
ASSIGNEE(S)	UNIVERSITY OF NORTH TEXAS (Denton, Texas)
INVENTOR(S)	Mohammad A. Omary (Denton, Texas); Sreekar Marpu (Denton, Texas)
ABSTRACT	Size-tunable phosphorescent particles may be formed through self-assembly of biocompatible linear polymers, such as chitosan and other linear polymers, that bear positive surface charges, through polyelectrolytic complexation to a polyanionic metal phosphor, such as polyanionic gold(I) phosphor (AuP). The phosphorescent hydrogel nanoparticles and thin films thereof are useful for imaging, sensing of biological molecules, detection of hypoxia, and light-emitting devices. The phosphorescent hydrogel particles can be formed from a variety of linear polymers by physical cross-linking using polyelectrolytic light-emitting species, without the need for the phosphorescent complex to be entrapped in an existing microsphere or nanosphere polymer particle.
FILED	Wednesday, November 30, 2016
APPL NO	15/365031
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) B82Y 20/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 2305/08 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 11/025 (20130101) C09K 11/70 (20130101) C09K 11/87 (20130101) C09K 11/0883 (20130101) Original (OR) Class C09K 2211/188 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/92 (20130101) Y10S 977/774 (20130101) Y10S 977/896 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

10255352 — Social media mining system for early detection of civil unrest events

US 10255352	Xu et al.
FUNDED BY
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Jiejun Xu (Chino, California); Tsai-Ching Lu (Wynnewood, Pennsylvania); Ryan F. Compton (Los Angeles, California); David L. Allen (Thousand Oaks, California)
ABSTRACT	Described is a system for early detection of events via social media mining. The system receives, as input, social media blog posts comprising textual data. The system processes the social media blog posts through a cascade of filters. The cascade of filters comprises an event term detection filter, a location term detection filter following the event term detection filter, and a future date detection filter following the location term detection filter. A plurality of candidate social media blog posts describing an event of interest on a future date is output to a user for further analysis.
FILED	Friday, November 07, 2014
APPL NO	14/535812
ART UNIT	2121 — AI & Simulation/Modeling
CURRENT CPC	Electric Digital Data Processing G06F 17/30699 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 5/04 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10255557 — XX Coupler for flux qubits

US 10255557	Epstein et al.
FUNDED BY
APPLICANT(S)	Ryan J. Epstein (Denver, Colorado); David George Ferguson (Takoma Park, Maryland)
ASSIGNEE(S)	NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S)	Ryan J. Epstein (Denver, Colorado); David George Ferguson (Takoma Park, Maryland)
ABSTRACT	Systems and methods are provided for coupling two flux qubits. A quantum circuit assembly includes a first flux qubit, having at least two potential energy minima, and a second flux qubit, having at least two potential energy minima. A system formed by the first and second qubits has at least four potential energy minima prior to coupling, each of the four potential energy minima containing at least one eigenstate of a system comprising the first flux qubit and the second flux qubit. A coupler creates a first tunneling path between a first potential energy minimum of the system and a second potential energy minimum of the system, and a second tunneling path between a third potential energy minimum of the system and a fourth potential energy minimum of the system. The coupler creates the first and second tunneling paths between potential energy minima representing states of equal bit parity.
FILED	Wednesday, February 15, 2017
APPL NO	15/433730
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Original (OR) Class Pulse Technique H03K 19/195 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10256836 — Resolver to digital conversion apparatus and method

US 10256836	Bird et al.
FUNDED BY
APPLICANT(S)	RAYTHEON COMPANY (Waltham, Massachusetts)
ASSIGNEE(S)	RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S)	Marcos Bird (McKinney, Texas); Brian D. Pautler (The Colony, Texas)
ABSTRACT	A resolver to digital converter is provided and includes first and second inputs to receive signals from a resolver and an output to provide an estimated angle of a rotor. The sine component signal is multiplied by the cosine of the estimated angle and the cosine component signal is multiplied by the sine of the estimated angle, and a difference between them is calculated to provide an error measurement. The estimated angle is updated by the error measurement.
FILED	Thursday, June 21, 2018
APPL NO	16/014097
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/204 (20130101) Coding; Decoding; Code Conversion in General H03M 1/485 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10257448 — Extended dynamic range imaging sensor and operating mode of the same

US 10257448	Tower et al.
FUNDED BY
APPLICANT(S)	SRI International (Menlo Park, California)
ASSIGNEE(S)	SRI International (Menlo Park, California)
INVENTOR(S)	John Robertson Tower (Yardley, Pennsylvania); Robert Michael Guidash (Rochester, New York); Peter Alan Levine (West Windsor, New Jersey); Rui Zhu (Princeton, New Jersey)
ABSTRACT	An imaging system for capturing light over a wide dynamic range and method for operating the same are provided. In some aspects, the method includes positioning an imaging pixel to image a scene described by light signals that extend over a wide dynamic range, and selecting a different integration time for at least two photodiodes in the imaging pixel based on light signals received by the imaging pixel, wherein the photodiodes are coupled to a sense node, and each photodiode is controlled using a different transfer gate. The method also includes performing a readout of the imaging pixel using a readout circuit connected to the sense node, wherein a capacitance associated with the sense node is modified during the readout of the at least two photodiodes.
FILED	Tuesday, August 16, 2016
APPL NO	15/238063
ART UNIT	2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14614 (20130101) H01L 27/14621 (20130101) H01L 27/14643 (20130101) Pictorial Communication, e.g Television H04N 5/355 (20130101) Original (OR) Class H04N 5/378 (20130101) H04N 5/3535 (20130101) H04N 5/3559 (20130101) H04N 5/3741 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, April 09, 2019.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190409.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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