FedInvent™ Patents

Patent Details for Tuesday, April 16, 2019

This page was updated on Monday, March 27, 2023 at 05:46 AM GMT

Department of Health and Human Services (HHS)

10258027 — Autodissemination of an insect-growth regulator for insect management

US 10258027	Gaugler et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) Small Business Administration (SBA) Small Business Innovation Research (SBIR) Department of Agriculture (USDA) Agricultural Research Service (ARS)
APPLICANT(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S)	Randy Gaugler (North Brunswick, New Jersey); Devi Suman (New Brunswick, New Jersey); Yi Wang (South River, New Jersey)
ABSTRACT	The described invention provides a gel formulation of a composition comprising at least one insecticide in an amount effective to control an insect larval population, an apparatus for autodissmenination of an insecticide for insect management containing (1) a reservoir (2) a transfer plate and cover, and (3) a mesh component, a method and a system for autodissemination for effectively controlling an insect larval population. Also disclosed is an improvided biphasic autodissemination station for control of undesirable insect populations.
FILED	Monday, February 22, 2016
APPL NO	15/050439
ART UNIT	3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/02 (20130101) A01M 1/20 (20130101) A01M 1/2005 (20130101) Original (OR) Class A01M 1/2011 (20130101) A01M 1/2016 (20130101) A01M 2200/011 (20130101) A01M 2200/012 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/00 (20130101) A01N 25/00 (20130101) A01N 25/04 (20130101) A01N 25/04 (20130101) A01N 25/04 (20130101) A01N 25/24 (20130101) A01N 25/24 (20130101) A01N 25/24 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258074 — Glycomacropeptide medical foods for nutritional management of phenylketonuria and other metabolic disorders

US 10258074	Ney et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisonsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Denise M. Ney (Brooklyn, Wisconsin); Mark R. Etzel (Madison, Wisconsin)
ABSTRACT	Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria.
FILED	Friday, May 09, 2014
APPL NO	14/274253
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/17 (20160801) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 38/018 (20130101) A61K 38/018 (20130101) A61K 2300/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258238 — Method and apparatus for OCT-based viscometry

US 10258238	Boppart et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Stephen A. Boppart (Champaign, Illinois); Guillermo Luciano Monroy (Burbank, Illinois); Paritosh Pande (Richland, Washington)
ABSTRACT	Methods and apparatus for ascertaining a relative viscosity characterizing a fluid sample. The fluid sample is illuminated through a scattering membrane adjacent to the fluid with broadband radiation. Scattering from particles within the fluid sample characterized by a distribution of characteristic dimensions spanning at least two orders of magnitude is detected, generating a detector signal as a function of depth relative to a specified surface of the scattering membrane at a plurality of temporal delays. A cross-correlation function of at least one of amplitude, phase and intensity of a scattered optical field is derived for a plurality of depths relative to the specified surface. A mean cross-correlation function is then derived for each depth and fit to obtain a diffusion coefficient, from which a relative viscosity characterizing the fluid is derived.
FILED	Friday, January 26, 2018
APPL NO	15/880734
ART UNIT	2886 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/227 (20130101) A61B 5/0066 (20130101) Original (OR) Class A61B 5/0075 (20130101) A61B 5/7257 (20130101) A61B 6/032 (20130101) A61B 6/508 (20130101) A61B 2503/40 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02044 (20130101) G01B 9/02091 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 11/00 (20130101) G01N 21/4795 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258242 — Near-infrared optical imaging system for hemodynamic imaging, pulse monitoring, and mapping spatio-temporal features

US 10258242	Godavarty et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Anuradha Godavarty (Miami, Florida); Youngjin Jung (Miami, Florida)
ASSIGNEE(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S)	Anuradha Godavarty (Miami, Florida); Youngjin Jung (Miami, Florida)
ABSTRACT	The present application describes techniques to image biological tissue to determine biological information of an imaged tissue sample such as changes in hemoglobin concentrations, blood flow rate (pulse), and/or spatio-temporal features. Embodiments include illuminating the tissue sample with light in the near-infrared (NIR) spectrum, which is minimally absorbed but scattered through the tissue sample. By detecting the NIR light that is attenuated through, transmitted through, and/or reflected off the tissue to be imaged, the resulting NIR intensity signals may be further analyzed to provide this data. Embodiments include using multiple NIR light sources having varying wavelengths to obtain changes in the oxy- and deoxy-hemoglobin concentrations of the imaged tissue region. The tissue sample may be imaged over a time period, and the NIR images may be viewed statically or in real time after post-processing analyses have been performed.
FILED	Tuesday, January 06, 2015
APPL NO	14/590703
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0059 (20130101) A61B 5/065 (20130101) A61B 5/742 (20130101) A61B 5/02028 (20130101) Original (OR) Class A61B 5/02416 (20130101) A61B 5/7207 (20130101) A61B 5/14551 (20130101) A61B 2560/0431 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) G01J 3/0264 (20130101) G01J 3/0272 (20130101) G01J 3/2823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2021/3155 (20130101) G01N 2201/0221 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258246 — Direct inversion for phase-based dynamic magnetic resonance measurements

US 10258246	Ahmad et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S)	Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S)	Rizwan Ahmad (Columbus, Ohio); Orlando P. Simonetti (Columbus, Ohio); Yu Ding (Hilliard, Ohio); Ning Jin (Columbus, Ohio)
ABSTRACT	MRI techniques seek to simultaneously measure physiological parameters in multiple directions, requiring the application of multiple encoding magnetic field gradient waveforms. The use of multiple encoding waveforms degrades the temporal resolution of the measurement, or may distort the results depending on the methodology used to derive physiological parameters from the measured data. The disclosed Direct Inversion Reconstruction Method (DiR) provides distortion-free velocity images with high temporal resolution, without changing the method of acquiring the phase data. The disclosed method provides a more stable and accurate recovery of phase-based dynamic magnetic resonance signals with higher temporal resolution than current state-of-the-art methods.
FILED	Tuesday, April 22, 2014
APPL NO	14/258268
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0263 (20130101) Original (OR) Class A61B 5/7203 (20130101) A61B 5/7239 (20130101) A61B 6/504 (20130101) A61B 2576/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/00 (20130101) G01R 33/20 (20130101) G01R 33/44 (20130101) G01R 33/48 (20130101) G01R 33/54 (20130101) G01R 33/56 (20130101) G01R 33/482 (20130101) G01R 33/56308 (20130101) G01R 33/56316 (20130101) Image Data Processing or Generation, in General G06T 11/005 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258314 — Systems and methods for super-resolution ultrasound imaging

US 10258314	Hynynen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Kullervo Hynynen (Toronto, Canada); Meaghan O'Reilly (Toronto, Canada); Foroohar Foroozan (Richmond Hill, Canada)
ASSIGNEE(S)	SUNNYBROOK RESEARCH INSTITUTE (Toronto, Canada)
INVENTOR(S)	Kullervo Hynynen (Toronto, Canada); Meaghan O'Reilly (Toronto, Canada); Foroohar Foroozan (Richmond Hill, Canada)
ABSTRACT	Systems and methods for ultrasound imaging capable of achieving spatial resolutions that can resolve objects smaller than 300 μm are described. Ultrasound is transmitted to and steered over a volume-of-interest that contains a microbubble contrast agent to individually excite microbubbles. Signal data is acquired in response to the transmitted ultrasound, and a plurality of images are reconstructed by beamforming the acquired signal data. The spatial resolution of the beamformed images can be further increased using techniques that determine the position of the microbubble within each image to a greater level of accuracy than the point spread function (“PSF”) of the ultrasound system. The images can also be combined to produce a single high resolution image of the volume-of-interest using, for instance, a maximum pixel projection technique.
FILED	Friday, May 02, 2014
APPL NO	14/888523
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 8/54 (20130101) A61B 8/481 (20130101) A61B 8/0808 (20130101) A61B 8/0891 (20130101) A61B 8/4494 (20130101) A61B 8/5207 (20130101) A61B 8/5238 (20130101) Original (OR) Class A61B 8/5246 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52039 (20130101) G01S 7/52047 (20130101) G01S 7/52049 (20130101) G01S 15/8922 (20130101) G01S 15/8929 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258509 — In-ear noise dosimetry system

US 10258509	Parkins
FUNDED BY	Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Red Tail Hawk Corporation (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Red Tail Hawk Corporation (Philadelphia, Pennsylvania)
INVENTOR(S)	John W. Parkins (Philadelphia, Pennsylvania)
ABSTRACT	An in-ear noise dosimeter in the form of an earplug which senses sound in the ear canal using an eartip which has a sound delivery channel that couples sound at the end closest to the eardrum to an earplug microphone. The earplug can communicate wirelessly with a remote data collection and processing system. A dock unit for storing the earplugs when not worn can compensate for differences in unoccluded-ear versus occluded-ear responses by an acoustic compensator. An electronic compensation filter can be modified by a proximity switch in the earplug which changes state when the earplug is worn in the ear versus stored in a dock unit. The dosimeter can also have a temperature sensor for sensing human body temperature and remotely-located wireless LEDs used to alert the user of high noise dosage. Data can also be downloaded from the earplug using a reader unit.
FILED	Wednesday, April 26, 2017
APPL NO	15/497970
ART UNIT	2654 — Audio Signals
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/12 (20130101) A61B 5/6817 (20130101) A61B 2560/0242 (20130101) A61B 2562/0204 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 11/08 (20130101) Original (OR) Class Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/1016 (20130101) H04R 1/1041 (20130101) H04R 1/1083 (20130101) H04R 2420/07 (20130101) H04R 2460/15 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258531 — Systems and methods for inhibiting apneic events

US 10258531	Paydarfar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	David Paydarfar (Newton, Massachusetts); Riccardo Barbieri (Boston, Massachusetts); Premananda Pai Indic (Northborough, Massachusetts); Ruby Kandah (Boston, Massachusetts); James Brian Niemi (Concord, Massachusetts); John Paul Osborne (Winchester, Massachusetts); Hani M. Sallum (Somerville, Massachusetts); Amanda V. Wozniak (Somerville, Massachusetts)
ASSIGNEE(S)	PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S)	David Paydarfar (Newton, Massachusetts); Riccardo Barbieri (Boston, Massachusetts); Premananda Pai Indic (Northborough, Massachusetts); Ruby Kandah (Boston, Massachusetts); James Brian Niemi (Concord, Massachusetts); John Paul Osborne (Winchester, Massachusetts); Hani M. Sallum (Somerville, Massachusetts); Amanda V. Wozniak (Somerville, Massachusetts)
ABSTRACT	Systems and methods are disclosed to monitor physiological for the occurrence of life threatening events and to apply stimulation to prevent the occurrence of said life-threatening events. Systems and methods for applying the stimulation are also disclosed. These systems include applying the stimulation through via a mattress having a passive section and an active section, a plurality of focal stimulators, and/or an array to apply the stimulation are also disclosed. These devices include a mattress with an active region and a passive region, a stimulating array do deliver targeted stimulation, and a plurality of stimulators to apply focused stimulation.
FILED	Thursday, August 30, 2012
APPL NO	14/342050
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/03 (20130101) A61B 5/11 (20130101) A61B 5/024 (20130101) A61B 5/0468 (20130101) A61B 5/0816 (20130101) A61B 5/02055 (20130101) A61B 5/4818 (20130101) A61B 5/4836 (20130101) A61B 5/6892 (20130101) A61B 5/7275 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/56 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/001 (20130101) A61H 1/005 (20130101) Original (OR) Class A61H 23/0245 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/02 (20130101) A61M 2021/0022 (20130101) Electric Digital Data Processing G06F 19/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258587 — Branched chain fatty acids for prevention or treatment of gastrointestinal disorders

US 10258587	Brenna et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	James Thomas Brenna (Ithaca, New York); Rinat Ran-Ressler (Ithaca, New York)
ABSTRACT	The present invention is directed to a method of preventing or treating a gastrointestinal condition in a subject, that includes administering one or more branched chain fatty acid to the subject under conditions effective to prevent or treat the gastrointestinal condition in the subject. The present invention is also directed to methods of promoting gastrointestinal health in a subject and propagation of probiotic organisms. Also disclosed is a formulation which includes one or more branched chain fatty acid and an aqueous phase emulsified with the one or more branched chain fatty acids, where the formulation includes over 25 wt % of the one or more branched chain fatty acid.
FILED	Tuesday, November 17, 2015
APPL NO	14/943500
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/12 (20160801) A23L 33/127 (20160801) A23L 33/135 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/19 (20130101) A61K 31/20 (20130101) Original (OR) Class A61K 31/20 (20130101) A61K 31/201 (20130101) A61K 35/741 (20130101) A61K 35/741 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 1/38 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101)
VIEW PATENT	@ USPTO: Full Text PDF

10258589 — Nitrated-fatty acids modulation of type II diabetes

US 10258589	Freeman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Bruce A. Freeman (Pittsburgh, Pennsylvania); Francisco J. Schopfer (Pittsburgh, Pennsylvania)
ABSTRACT	Nitro oleic acid and related metabolites are agonists of PPAR-γ. Surprisingly, nitro oleic acid is a more potent agonist of PPAR-γ, relative to nitro linoleic acid. Thus, nitro oleic acid and its metabolites, as well as their pharmaceutically acceptable salts and prodrug forms, are candidate therapeutics for the treatment of type-2 diabetes, which results from insulin resistance accompanying the improper functioning of PPAR-γ.
FILED	Wednesday, June 21, 2017
APPL NO	15/629277
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/20 (20130101) A61K 31/201 (20130101) Original (OR) Class A61K 45/06 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258600 — Aryl hydrocarbon receptor (AhR) modifiers as novel cancer therapeutics

US 10258600	Sherr et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S)	Trustees of Boston University (Boston, Massachusetts); Northeastern University (Boston, Massachusetts); Boston Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S)	Trustees of Boston University (Boston, Massachusetts); Boston Medical Center (Boston, Massachusetts); Northeastern University (Boston, Massachusetts)
INVENTOR(S)	David H. Sherr (West Roxbury, Massachusetts); Michael Pollastri (Waltham, Massachusetts); Jennifer Schlezinger (East Falmouth, Massachusetts); Sarah Haigh Molina (Boston, Massachusetts); Scott Schaus (Boston, Massachusetts); Joshua Robert Giguere (Sharon, Massachusetts)
ABSTRACT	Provided herein are novel agents that modulate AhR activity for use in therapeutic compositions and methods thereof for inhibiting cancer cell proliferation and tumor cell invasion and metastasis. The agents comprise AhR inhibitors or non-constitutive AhR agonists of Formula (I) and (II) for the inhibition of cancer cell growth and parameters that characterize tumor metastasis, such as tumor cell invasiveness.
FILED	Thursday, March 03, 2016
APPL NO	15/059911
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/35 (20130101) A61K 31/35 (20130101) A61K 31/35 (20130101) A61K 31/352 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 311/22 (20130101) C07D 407/04 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258606 — Endothelin single nucleotide polymorphisms and methods of predicting β-adrenergic receptor targeting agent efficacy

US 10258606	Taylor et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Regents of the University of Colorado, A Body Corporate (Denver, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado, A Body Corporate (Denver, Colorado)
INVENTOR(S)	Matthew R. G. Taylor (Denver, Colorado); Luisa Mestroni (Boulder, Colorado)
ABSTRACT	The present invention concerns the use of methods for evaluating β-adrenergic receptor targeting agent treatment for a patient, particularly one with a heart condition. In general, the disclosed methods entail determining the presence or absence of one or more polymorphisms in an endothelin gene system member. Based on the results of this determination, a β-adrenergic receptor targeting agent may be prescribed, administered or a treatment regimen altered, including the administration of a β-blocker. Accordingly, methods of treatment are also described.
FILED	Monday, June 22, 2015
APPL NO	14/746362
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/4045 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

10258612 — Mitochondrial lipid permeable iron chelators for treating and preventing ischemia/reperfusion (I/R) injury in the heart following an ischemic event

US 10258612	Ardehali et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Hossein Ardehali (Hinsdale, Illinois); Hsiang-Chun Chang (Chicago, Illinois)
ABSTRACT	Disclosed are methods and compositions for treating or preventing a disease or disorder responsive to a decrease in baseline mitochondrial iron in a subject in need thereof. The methods typically include administering a pharmaceutical composition comprising a mitochondrial permeable iron chelator to the subject.
FILED	Wednesday, July 13, 2016
APPL NO	15/209261
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/16 (20130101) A61K 31/444 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10258613 — Compositions for treating retinal degeneration and methods of production and use thereof

US 10258613	Ding et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S)	Xi-Qin Ding (Edmond, Oklahoma); Hongwei Ma (Edmond, Oklahoma)
ABSTRACT	Compositions for use in methods of treating and/or inhibiting a pathologic ocular condition, as well as methods of producing and using same, are disclosed.
FILED	Thursday, February 05, 2015
APPL NO	15/115819
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/09 (20130101) A61K 31/16 (20130101) A61K 31/17 (20130101) A61K 31/35 (20130101) A61K 31/085 (20130101) A61K 31/192 (20130101) A61K 31/341 (20130101) A61K 31/451 (20130101) Original (OR) Class A61K 31/473 (20130101) A61K 31/495 (20130101) A61K 31/4409 (20130101) A61K 31/4412 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258615 — Methods of treating a neurodegenerative disease in a mammal in need thereof

US 10258615	Trotti et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Thomas Jefferson University (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Thomas Jefferson University (Philadelphia, Pennsylvania)
INVENTOR(S)	Davide Trotti (Bala Cynwyd, Pennsylvania); Piera Pasinelli (Bala Cynwyd, Pennsylvania); Michael R. Jablonski (Philadelphia, Pennsylvania)
ABSTRACT	The present invention provides a method of treating or ameliorating a neurodegenerative disease in a mammal, the method comprising administering to the mammal a therapeutically effective amount of a neurodegenerative disease drug, wherein the drug is a substrate of an ABC transporter inhibitor, wherein the mammal is further administered a therapeutically effective amount of an ABC transporter inhibitor, whereby the neurodegenerative disease is treated in the mammal. In certain embodiments, the neurodegenerative disease comprises at least one selected from the group consisting of spinal cord injury, Alzheimer's disease, Parkinson's disease, Huntington's disease, prion disease, amyotrophic lateral sclerosis, a tauopathy, and chronic traumatic encephalopathy.
FILED	Tuesday, December 09, 2014
APPL NO	15/103234
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/55 (20130101) A61K 31/428 (20130101) A61K 31/428 (20130101) A61K 31/473 (20130101) Original (OR) Class A61K 31/473 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/4725 (20130101) A61K 31/4725 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258618 — Treating pulmonary conditions by selectively removing senescent cells from the lung using an intermittent dosing regimen

US 10258618	Laberge et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	Buck Institute for Research on Aging (Novato, California); Unity Biotechnology, Inc. (Brisbane, California); Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S)	UNITY BIOTECHNOLOGY, INC. (Brisbane, California); BUCK INSTITUTE FOR RESEARCH AGING (Novato, California); MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota)
INVENTOR(S)	Remi-Martin Laberge (San Francisco, California); Judith Campisi (Berkeley, California); Marco Demaria (Gronigen, Netherlands); Nathaniel David (Brisbane, California); Darren J. Baker (Rochester, Minnesota); James L. Kirkland (Rochester, Minnesota); Tamar Tchkonia (Rochester, Minnesota); Yi Zhu (Rochester, Minnesota); Jan M. A. van Deursen (Rochester, Minnesota)
ABSTRACT	Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders.
FILED	Tuesday, April 17, 2018
APPL NO	15/955542
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0073 (20130101) A61K 31/404 (20130101) A61K 31/428 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/728 (20130101) A61K 31/4178 (20130101) A61K 31/4375 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 47/36 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0081 (20130101) C12N 2501/999 (20130101) C12N 2503/02 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258625 — Method for treatment of metastatic and refractory cancers and tumors with an inducer that overcomes inhibition of T cell proliferation

US 10258625	Conejo-Garcia et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania)
INVENTOR(S)	Jose R. Conejo-Garcia (Philadelphia, Pennsylvania); Michael Allegrezza (Philadelphia, Pennsylvania)
ABSTRACT	A method of treating a mammalian subject with cancer comprises administering to said subject having a cancer, e.g., a metastatic or refractory cancer or tumor, a small molecule inhibitor of a target signaling molecule of the MEK/MAPK pathway that impairs T cell activation, and administering to said subject a molecule that induces T cell proliferation in the presence of said inhibitor. The combination of a small molecule inhibitor of a target of the MEK/MAPK pathway and the T cell proliferation inducer reduces the proliferation of the cancer and tumor cells in vivo. Compositions and kits including these components are also provided.
FILED	Thursday, July 27, 2017
APPL NO	15/661100
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 8/4946 (20130101) A61K 9/19 (20130101) A61K 31/18 (20130101) A61K 31/18 (20130101) A61K 31/145 (20130101) A61K 31/166 (20130101) A61K 31/277 (20130101) A61K 31/277 (20130101) A61K 31/397 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/4184 (20130101) A61K 31/4184 (20130101) A61K 31/4458 (20130101) A61K 31/4523 (20130101) A61K 31/4523 (20130101) A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 38/1793 (20130101) A61K 38/2013 (20130101) A61K 38/2046 (20130101) A61K 38/2086 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Peptides C07K 14/5418 (20130101) C07K 14/5443 (20130101) C07K 14/7155 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Enzymes C12Y 207/11024 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258629 — Liposomal drug encapsulation

US 10258629	Kesari et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Santosh Kesari (San Diego, California); Rajesh Mukthavaram (La Jolla, California); Milan T. Makale (San Diego, California); Wolfgang J. Wrasidlo (La Jolla, California)
ABSTRACT	Provided herein are compositions methods of using liposomally encapsulated therapeutic drugs, such as staurosporine. Further provided herein are methods of using the liposome compositions to treat a cancer.
FILED	Friday, March 27, 2015
APPL NO	15/129317
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 9/1271 (20130101) A61K 9/1278 (20130101) A61K 31/553 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10258635 — Formulations and compositions of vitamin D analogs for treating and preventing cancer and other diseases

US 10258635	Castor
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Aphios Corporation (Woburn, Massachusetts)
ASSIGNEE(S)	Aphios Corporation (Woburn, Massachusetts)
INVENTOR(S)	Trevor P. Castor (Arlington, Massachusetts)
ABSTRACT	This invention is for formulations of analogs of the non-toxic and inert Vitamin D3, its non-toxic and mostly inert pre-hormone and its toxic and biologically active hormone, and for using these formulations for preventing and treating certain cancers such as breast, prostate, ovarian, kidney, renal and other cancers, Vitamin D deficiency, autoimmune disease such as Multiple Sclerosis, hypertension, osteoporosis, bone diseases, rickets, psoriasis and infectious diseases. This invention also discloses compositions of the analogs of the non-toxic and inert Vitamin D3 and the non-toxic and mostly inert Vitamin D3 pre-hormone.
FILED	Tuesday, March 08, 2016
APPL NO	15/064389
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/127 (20130101) A61K 9/4858 (20130101) A61K 9/4866 (20130101) A61K 9/4875 (20130101) A61K 9/5153 (20130101) A61K 31/593 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10258638 — Administration of nicotinamide mononucleotide in the treatment of disease

US 10258638	Imai
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	Washington University (Saint Louis, Missouri)
ASSIGNEE(S)	Washington University (Saint Louis, Missouri)
INVENTOR(S)	Shin-ichiro Imai (Saint Louis, Missouri)
ABSTRACT	Disclosed are methods and compositions related to methods of treating, ameliorating, mitigating, slowing, arresting, preventing or reversing various diseases and conditions, including age-related obesity, age-related increases in blood lipid levels, age-related decreases in insulin sensitivity, age-related decreases in memory function, and age-related changes in eye function such as macular degeneration. The methods comprise administering nicotinamide mononucleotide (NMN) to a subject. In some embodiments, the administration can be oral administration. Also disclosed are pharmaceutical compositions comprising NMN.
FILED	Friday, October 13, 2017
APPL NO	15/783845
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0048 (20130101) A61K 9/0053 (20130101) A61K 31/455 (20130101) A61K 31/706 (20130101) Original (OR) Class A61K 31/7064 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258639 — Methods for treating insulin resistance and for sensitizing patients to GLP1 agonist therapy

US 10258639	Montminy et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Research Development Foundation (Carson City, Nevada)
ASSIGNEE(S)	Research Development Foundation (Carson City, Nevada)
INVENTOR(S)	Marc Montminy (La Jolla, California); Sam Van De Velde (La Jolla, California); Emilie Blanchet (La Jolla, California)
ABSTRACT	Methods for treatment of insulin resistance and type II diabetes by administration of inhibitors of the PKI pathway are provided. In some aspects, inhibitors of the PKI pathway, such as inhibitors of PIKB, HIF1 and/or mTOR, can be used to treat subject having insulin resistance who are refractory to GLP1 agonist therapy.
FILED	Wednesday, May 06, 2015
APPL NO	15/308652
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/565 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 38/26 (20130101) A61K 38/26 (20130101) A61K 2300/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258641 — Hydroxypropyl beta-cyclodextrin compositions and methods

US 10258641	Machielse et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Vtesse Inc. (Rockville, Maryland)
ASSIGNEE(S)	VTESSE INC. (Hazelwood, Missouri)
INVENTOR(S)	Bernardus Nicolaas Machielse (North Potomac, Maryland); Allan Darling (North Potomac, Maryland)
ABSTRACT	This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
FILED	Thursday, April 27, 2017
APPL NO	15/499831
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/724 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10258668 — Viral vectors for expressing a modified mullerian inhibiting substance (MIS) protein

US 10258668	Donahoe et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); MASSACHUSETTS EYE AND EAR INFIRMARY (Boston, Massachusetts); UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts); Massachusetts Eye and Ear Infirmary (Boston, Massachusetts); University of Massachusetts (Boston, Massachusetts)
INVENTOR(S)	Patricia K. Donahoe (Boston, Massachusetts); Demetrios Vavvas (Boston, Massachusetts); David Pepin (Somerville, Massachusetts); Mien Van Hoang (Braintree, Massachusetts); Robert H. Brown, Jr. (Worcester, Massachusetts); Guangping Gao (Worcester, Massachusetts)
ABSTRACT	The present invention relates to methods to treat a neurodegenerative disease or disorder, e.g., a motor neuron disease in a subject, whereby the subject is administered a recombinant human Mullerian Inhibiting Substance (MIS) protein as disclosed herein, wherein the recombinant human MIS protein comprises a modified Kex cleavage site for increased cleavage. The recombinant human MIS protein can be produced from a pre-proprotein comprising a non-MIS leader sequence or a functional fragment thereof in place of the MIS leader sequence.
FILED	Wednesday, March 12, 2014
APPL NO	15/023044
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/22 (20130101) Original (OR) Class A61K 48/0058 (20130101) A61K 48/0066 (20130101) Peptides C07K 14/575 (20130101) C07K 14/765 (20130101) C07K 16/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2750/14143 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258672 — Compositions and methods of treating root avulsion injury

US 10258672	Silver et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); THE UNIVERSITY OF HONG KONG (Hong Kong, China Hong Kong)
INVENTOR(S)	Jerry Silver (Cleveland, Ohio); Bradley T. Lang (Cleveland, Ohio); Jared M. Cregg (Cleveland, Ohio); Yi-Lan Weng (Cleveland, Ohio); Heng Li (Pok Fu Iam, China Hong Kong); Wutian Wu (Pok Fu Lam, China Hong Kong)
ABSTRACT	A method of treating root avulsion injury in a subject in need thereof includes administering to the subject a therapeutic agent that inhibits one or more of catalytic activity, signaling, and function of PTPσ.
FILED	Friday, September 23, 2016
APPL NO	15/274236
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/005 (20130101) A61K 38/465 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 2039/5158 (20130101) A61K 2039/55522 (20130101) Peptides C07K 2319/10 (20130101) Enzymes C12Y 301/03048 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258677 — Continuous cell programming devices

US 10258677	Mooney et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S)	David J. Mooney (Sudbury, Massachusetts); Omar Abdel-Rahman Ali (Cambridge, Massachusetts); Glenn Dranoff (Sudbury, Massachusetts)
ABSTRACT	The present invention comprises compositions, methods, and devices for creating an infection-mimicking environment within a polymer scaffold to stimulate antigen-specific dendritic cell activation. Devices of the present invention are used to provide protective immunity to subjects against infection and cancer.
FILED	Thursday, April 21, 2016
APPL NO	15/135255
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/708 (20130101) A61K 31/4745 (20130101) A61K 31/7088 (20130101) A61K 38/193 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2039/54 (20130101) A61K 2039/6093 (20130101) A61K 2039/55516 (20130101) A61K 2039/55522 (20130101) A61K 2039/55561 (20130101) A61K 2039/55588 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258682 — Attenuated chlamydia vaccine

US 10258682	Caldwell
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Harlan D. Caldwell (Hamilton, Montana)
ABSTRACT	The invention provides vectors, attenuated pathogens, compositions, methods, and kits for use in preventing or treating infection by an infectious pathogen, especially Chlamydia trachomatis. The vectors comprise the plasmid encoded ppg genes from Chlamydia, ppg1, ppg2, ppg3, ppg5, ppg6, ppg7 and/or ppg8, but lack ppg4, a regulator of virulence associated genes. The application also provides attenuated pathogens, especially chlamydia, which are cured of their plasmid and have additional mutations to improve the attenuation, especially mutations in the CT135 gene or in the tryptophan operon (trp promoter, trpA, or trpB). Uses of said nucleic acids and attenuated pathogens for inducing or modulating an immune response in a subject, especially for prevention or treatment of infections, are proposed.
FILED	Thursday, January 16, 2014
APPL NO	14/761520
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/118 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/522 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) C12N 15/74 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258686 — Materials and methods for respiratory disease control in canines

US 10258686	Crawford et al.
FUNDED BY	Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC)
APPLICANT(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida); CORNELL RESEARCH FOUNDATION, INC. (Ithaca, New York); The United States of America as respresented by The Secretary of The Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida); CORNELL RESEARCH FOUNDATION, INC. (Ithaca, New York); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEAS CONTROL AND PREVENTION (Washington, District of Columbia)
INVENTOR(S)	Patti Cynthia Crawford (Gainesville, Florida); Paul J. Gibbs (Gainesville, Florida); Edward J. Dubovi (Ithaca, New York); Ruben Omar Donis (Atlanta, Georgia); Jacqueline Katz (Atlanta, Georgia); Alexander I. Klimov (Atlanta, Georgia); Nallakannu P. Lakshmanan (Millsboro, Delaware); Melissa Anne Lum (Millsboro, Delaware); Daniel Ghislena Emiel Goovaerts (Boxmeer, Netherlands); Mark William Mellencamp (Desoto, Kansas); Nancy J. Cox (Atlanta, Georgia); William L. Castleman (Gainesville, Florida)
ABSTRACT	The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention.
FILED	Monday, February 05, 2018
APPL NO	15/888715
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/552 (20130101) A61K 2039/5252 (20130101) A61K 2039/55555 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/005 (20130101) C07K 16/1018 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2710/24043 (20130101) C12N 2760/16121 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) C12N 2760/16151 (20130101) C12N 2760/16171 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/11 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258695 — Protein derivatization to endow cell penetration

US 10258695	Raines et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Ronald T. Raines (Madison, Wisconsin); Kristen A. Andersen (Madison, Wisconsin)
ABSTRACT	Methods and reagents for enhancing cellular uptake of a cargo molecule by covalently bonding optionally-substituted fluorenyl groups to the cargo molecules, where cellular uptake includes at least partial uptake into the cytosol. Useful fluorenylation reagents include those of formula: and salts thereof where variables are as defined. Cargo molecules include peptides and proteins. Also provided are fluorenylated cargo molecules, including fluorenylated peptides and proteins.
FILED	Thursday, September 03, 2015
APPL NO	14/845108
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/54 (20170801) Original (OR) Class Peptides C07K 1/13 (20130101) C07K 1/1077 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258700 — Methods and compositions for delivering active agents with enhanced pharmacological properties

US 10258700	Chilkoti
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	DUKE UNIVERSITY (Durham, North Carolina)
ASSIGNEE(S)	DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S)	Ashutosh Chilkoti (Durham, North Carolina)
ABSTRACT	Provided herein are methods of enhancing in vivo efficacy of an active agent, comprising: administering to a subject an active agent that is coupled to a bioelastic polymer or elastin-like peptide, wherein the in vivo efficacy of the active agent is enhanced as compared to the same active agent when administered to the subject not coupled to (or not associated with) a bioelastic polymer or ELP.
FILED	Thursday, November 12, 2015
APPL NO	14/939225
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/16 (20130101) A61K 38/17 (20130101) A61K 38/22 (20130101) A61K 38/23 (20130101) A61K 38/44 (20130101) A61K 38/45 (20130101) A61K 38/1709 (20130101) A61K 38/2264 (20130101) A61K 38/2271 (20130101) A61K 39/44 (20130101) A61K 47/64 (20170801) A61K 47/6435 (20170801) A61K 49/14 (20130101) Original (OR) Class A61K 49/0056 (20130101) A61K 2039/505 (20130101) Peptides C07K 2319/31 (20130101) Enzymes C12Y 113/12007 (20130101) C12Y 203/01028 (20130101) C12Y 203/02013 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258701 — Labeled evans blue dye derivative for in vivo serum albumin labeling

US 10258701	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Xiaoyuan Chen (Potomac, Maryland); Lixin Lang (North Potomac, Maryland); Gang Niu (Rockville, Maryland)
ABSTRACT	Disclosed is a compound of formula (I): wherein L, R¹-R⁵, A, B, M, and n are as defined in the specification, as well as a method of preparing the compound. Also disclosed are a method of blood-pool imaging in a mammal and a method of imaging a lymph node in a mammal, comprising use of the compound.
FILED	Friday, May 05, 2017
APPL NO	15/587948
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 51/0482 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 59/004 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 29/30 (20130101) C09B 45/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258729 — Integrated centrifugal blood pump-oxygenator, an extracorporeal life support system and a method of de-bubbling and priming an extracorporeal life support system

US 10258729	Gellman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Thoratec LLC (Pleasanton, California)
ASSIGNEE(S)	Thoratec LLC (Pleasanton, California); University of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S)	Barry N. Gellman (North Easton, Massachusetts); Andrew Koert (Somerville, Massachusetts); Zhongjun Wu (Woodstock, Maryland); Juntao Zhang (Baltimore, Maryland); Bartley P. Griffith (Gibson Island, Maryland)
ABSTRACT	A method for pumping and oxygenating blood includes receiving a flow of gas including oxygen into a gas inlet manifold via a gas inlet. The flow of gas is passed through the hollow fibers from the gas inlet manifold to a gas outlet manifold. The flow of gas is output from the gas outlet manifold via a gas outlet. An impeller is rotated to generate a flow of blood that flows over the hollow fibers. Oxygen from the flow of gas is transferred to the flow of blood through the hollow fibers. Carbon dioxide is transferred from the flow of blood to the flow of gas through the hollow fibers.
FILED	Thursday, January 28, 2016
APPL NO	15/009702
ART UNIT	3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/101 (20130101) A61M 1/262 (20140204) A61M 1/267 (20140204) A61M 1/1006 (20140204) A61M 1/1015 (20140204) A61M 1/1698 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10258734 — Devices, systems and methods for cell modification

US 10258734	Federspiel et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	William J. Federspiel (Pittsburgh, Pennsylvania); John Alston Kellum (Pittsburgh, Pennsylvania); Kai Singbartl (Pittsburgh, Pennsylvania)
ABSTRACT	A method of modifying cells includes removing fluid including cells from a patient, contacting the removed fluid from the patient with at least one surface upon which at least one agent to interact at least one cell receptor is immobilized to modify cells in the fluid, and returning the fluid to the patient. The agent can, for example, be immobilized via covalent bonding or ionic bonding to the at least one surface. The fluid can, for example, be blood or a blood fraction. The agent can, for example, be an agonist, an antagonist or an inverse agonist.
FILED	Wednesday, March 08, 2017
APPL NO	15/453817
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 2035/124 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3687 (20130101) A61M 1/3689 (20140204) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10258793 — Artifact control and miniaturization of the safe direct current stimulator for neural prostheses

US 10258793	Fridman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Gene Yevgeny Fridman (Baltimore, Maryland); Charles Coleman Della Santina (Towson, Maryland)
ABSTRACT	An embodiment in accordance with the present invention provides a device and method to deliver direct ionic current safely to target neural tissue, while also eliminating interruptions in the output of the device that can result from the non-ideal operation of the valves used to control the current flow in the device. The device includes two valve-operated systems that work in tandem. The first and second current producing systems are configured to be used together in order to eliminate the periodic interruptions in current flow. In use, one system drives current through the target tissue, while the other system closes all of the valves first and then opens its valves in sequence. This intermediate step of closing all of the valves prevents unintended current shunts through either system. The device also includes two conductors to direct the flow of direct current into the target tissue.
FILED	Monday, February 13, 2017
APPL NO	15/431272
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/20 (20130101) A61N 1/32 (20130101) A61N 1/44 (20130101) A61N 1/303 (20130101) Original (OR) Class A61N 1/325 (20130101) A61N 1/3605 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259779 — Structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity

US 10259779	Pflum
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	WAYNE STATE UNIVERSITY (Detroit, Michigan)
ASSIGNEE(S)	WAYNE STATE UNIVERSITY (Detroit, Michigan)
INVENTOR(S)	Mary Kay Pflum (Northville, Michigan)
ABSTRACT	A compound having formula I for histone deacetylase inhibition is provided: or a pharmaceutically acceptable salt or hydrate thereof wherein R is alkyl, C_6-18aryl, C_5-18heteroaryl, C_8-22alkylaryl, C_8-22alkylheteroaryl, or halo.
FILED	Friday, August 25, 2017
APPL NO	15/686794
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 259/06 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10259781 — Imaging agents

US 10259781	Raffel et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	David M. Raffel (Ann Arbor, Michigan); Yong-Woon Jung (Ann Arbor, Michigan); Keun-Sam Jang (Ann Arbor, Michigan)
ABSTRACT	Provided herein is technology relating to imaging agents and particularly, but not exclusively, to methods of manufacturing fluorine-18-labeled phenethylguanidines and uses thereof.
FILED	Thursday, February 08, 2018
APPL NO	15/891819
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/155 (20130101) A61K 51/04 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) C07B 59/002 (20130101) C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 277/06 (20130101) C07C 277/08 (20130101) C07C 279/06 (20130101) C07C 279/08 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10259804 — Anti-endothelial lipase compounds and methods of using the same in the treatment and/or prevention of cardiovascular diseases

US 10259804	Elshourbagy et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Shifa Biomedical Corporation (Malvern, Pennsylvania)
ASSIGNEE(S)	SHIFA BIOMEDICAL CORPORATION (Malvern, Pennsylvania)
INVENTOR(S)	Nabil Elshourbagy (West Chester, Pennsylvania); Shaker Mousa (Wynantskill, New York); Harold Meyers (Weston, Massachusetts)
ABSTRACT	Endothelial Lipase (EL) inhibitors and methods of using such inhibitors for treating conditions implicating EL are provided herein. The present invention meets the needs in the field by providing small molecule inhibitors of EL function that can be used therapeutically to raise HDL cholesterol levels in blood, and can be used in the prevention and/or treatment of cholesterol and lipoprotein metabolism disorders, including, but not limited to, familial hypercholesterolemia, atherogenic dyslipidemia, atherosclerosis, and, more generally, cardiovascular disease (CVD).
FILED	Wednesday, September 23, 2015
APPL NO	15/514157
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 307/66 (20130101) C07D 405/12 (20130101) Original (OR) Class C07D 405/14 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259815 — Gabaergic ligands and their uses

US 10259815	Cook et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	UWM Research Foundation, Inc. (Milwaukee, Wisconsin)
ASSIGNEE(S)	UWM Research Foundation, Inc. (Milwaukee, Wisconsin)
INVENTOR(S)	James Cook (Milwaukee, Wisconsin); Michael Ming-Jin Poe (Vernon, Connecticut); Kashi Reddy Methuku (Milwaukee, Wisconsin); Guanguan Li (Milwaukee, Wisconsin)
ABSTRACT	Described herein are α3 or α2 or α2/α3 GABAergic receptor subtype selective ligands, pharmaceutical compositions, and methods of use of such ligands and compositions in treatment of anxiety disorders, epilepsy and schizophrenia with reduced sedative and ataxic side effects. In embodiments, such as α3 or α2 or α2/α3 GABAergic receptor subtype selective ligands lack ester linkages and may be thus relatively insensitive to hydrolysis by esterases.
FILED	Friday, March 18, 2016
APPL NO	15/560002
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10259843 — Cyclic tetrapeptide stereoisomers

US 10259843	Aldrich et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	University of Kansas (Lawrence, Kansas)
ASSIGNEE(S)	University of Kansas (Lawrence, Kansas)
INVENTOR(S)	Jane V. Aldrich (Lawrence, Kansas); S P Sanjeewa Nilendra Senadheera (Lawrence, Kansas)
ABSTRACT	Cyclic tetrapeptide stereochemical isomers of CJ-15,208, pharmaceutical compositions from such cyclic tetrapeptides, and methods of using such pharmaceutical compositions. The cyclic tetrapeptide compounds and pharmaceutical compositions disclosed herein are potent analgesics active in several pain models with generally minimal tolerance and reduced likelihood to induce addiction relative to other known opiates.
FILED	Monday, July 13, 2015
APPL NO	15/325177
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 5/12 (20130101) C07K 5/126 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10259844 — Endometriosis cell targeting peptide and uses thereof

US 10259844	Fukuda et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Sanford-Burnham Medical Research Institute (LaJolla, California); Keio University (Tokyo, Japan); Noriko Nozawa (, None)
ASSIGNEE(S)	Sanford-Burnham Medical Research Institute (La Jolla, California)
INVENTOR(S)	Michiko Fukuda (LaJolla, California); Daisuke Aoki (Shinjuku-ku, Japan); Shiro Nozawa (Shibuya-ku, Japan)
ABSTRACT	Provided herein are compositions and methods for selectively targeting an endometriosis cell.
FILED	Friday, April 10, 2015
APPL NO	14/683520
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/7028 (20130101) A61K 38/08 (20130101) A61K 38/08 (20130101) A61K 45/06 (20130101) A61K 47/64 (20170801) A61K 49/0056 (20130101) A61K 2300/00 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Original (OR) Class C07K 14/001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) G01N 2800/364 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259845 — Peptides whose uptake by cells is controllable

US 10259845	Jiang et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Tao Jiang (Rancho Santa Fe, California); Emilia S. Olson (La Jolla, California); Michael Whitney (San Diego, California); Roger Tsien (La Jolla, California)
ABSTRACT	A generic structure for the peptides of the present invention includes A-X-B-C, where C is a cargo moiety, the B portion includes basic amino acids, X is a cleavable linker sequence, and the A portion includes acidic amino acids. The intact structure is not significantly taken up by cells; however, upon extracellular cleavage of X, the B-C portion is taken up, delivering the cargo to targeted cells. Cargo may be, for example, a contrast agent for diagnostic imaging, a chemotherapeutic drug, or a radiation-sensitizer for therapy. X may be cleaved extracellularly or intracellularly. The molecules of the present invention may be linear, cyclic, branched, or have a mixed structure.
FILED	Monday, June 29, 2015
APPL NO	14/753975
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0095 (20130101) A61K 47/64 (20170801) A61K 47/65 (20170801) A61K 47/645 (20170801) A61K 49/14 (20130101) A61K 49/0032 (20130101) A61K 49/0043 (20130101) A61K 49/0056 (20130101) A61K 49/085 (20130101) A61K 49/146 (20130101) A61K 51/088 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 14/00 (20130101) C07K 14/4728 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259854 — Engineered antibody-interferon mutant fusion molecules

US 10259854	Grewal et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	ImmunGene Inc. (Camarillo, California)
ASSIGNEE(S)	ImmunGene Inc (Camarillo, California)
INVENTOR(S)	Iqbal Grewal (Newtown, Pennsylvania); Sanjay Khare (Palo Alto, California); Michael Gresser (Ojai, California); Rashid Syed (Thousand Oaks, California)
ABSTRACT	The field of the present invention relates to genetically engineered fusion molecules, methods of making said fusion molecules, and uses thereof in anti-tumor immunotherapies. More specifically, the present invention relates to fusion molecule constructs wherein a tumor associated antigen (TAA) antibody (Ab) serves as a targeting moiety to selectively deliver a cytokine to a tumor cell for purposes of killing or inhibiting the growth or proliferation of said tumor cell. In various embodiments, the engineered fusion molecules comprise a TAA Ab fused to an interferon-alpha (IFN-α) mutant molecule. The engineered Ab-IFN-α mutant fusion molecules of the present invention demonstrate improved therapeutic index and preserved or increased efficacy as compared to Ab-wildtype IFN-α fusion molecules, and/or demonstrate improved PK properties as compared to Ab-wildtype IFN-α fusion molecules.
FILED	Monday, November 28, 2016
APPL NO	15/361902
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/212 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/56 (20130101) Original (OR) Class C07K 16/18 (20130101) C07K 16/30 (20130101) C07K 16/32 (20130101) C07K 16/2803 (20130101) C07K 16/2827 (20130101) C07K 16/2851 (20130101) C07K 16/2863 (20130101) C07K 16/2887 (20130101) C07K 16/2896 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/90 (20130101) C07K 2319/00 (20130101) C07K 2319/30 (20130101) C07K 2319/33 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259884 — Antibodies to GRP78

US 10259884	Hallahan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Washington University (St. Louis, Missouri)
ASSIGNEE(S)	Washington University (St. Louis, Missouri); Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Dennis E. Hallahan (St. Louis, Missouri); Heping Yan (St. Louis, Missouri)
ABSTRACT	The present invention is directed towards isolated antibodies that bind to GRP78.
FILED	Tuesday, June 20, 2017
APPL NO	15/628209
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/4848 (20130101) A61B 6/032 (20130101) A61B 6/463 (20130101) A61B 6/481 (20130101) A61B 6/508 (20130101) A61B 90/361 (20160201) Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 49/0058 (20130101) A61K 51/1045 (20130101) A61K 51/1066 (20130101) A61K 51/1093 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) A61N 2005/1087 (20130101) A61N 2005/1098 (20130101) Peptides C07K 16/18 (20130101) C07K 16/30 (20130101) Original (OR) Class C07K 16/3023 (20130101) C07K 16/3053 (20130101) C07K 2317/34 (20130101) C07K 2317/73 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260038 — Protein modification of living cells using sortase

US 10260038	Swee et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
ASSIGNEE(S)	Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S)	Lee Kim Swee (Heidelberg, Germany); Hidde L. Ploegh (Brookline, Massachusetts)
ABSTRACT	Non-genetically engineered mammalian cells modified by sortase-mediated conjugation of an agent thereto are provided. Methods of conjugating agents to nongenetically engineered mammalian cells using sortase are provided. Methods of using the cells, e.g. a method of modulating an immune response of a subject to an entity of interest, a method of neutralizing a substance in the body of a subject, a method of treating a subject in need of treatment for deficiency of a protein, and a method of treating a subject in need of treatment for a disease, are provided.
FILED	Friday, May 09, 2014
APPL NO	14/890296
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 47/65 (20170801) A61K 47/66 (20170801) A61K 47/68 (20170801) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0006 (20130101) Original (OR) Class C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 9/50 (20130101) Enzymes C12Y 304/2207 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260039 — Microgels and microtissues for use in tissue engineering

US 10260039	Bhatia et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Sangeeta N. Bhatia (Lexington, Massachusetts); Cheri Y. Li (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Sangeeta N. Bhatia (Lexington, Massachusetts); Cheri Y. Li (Cambridge, Massachusetts)
ABSTRACT	The present invention features microgels and microtissues for use in tissue engineering. Featured is a microencapsulation device for making microgels and/or microtissues via an emulsion technology. Also featured are methods of making higher ordered structures that mimic in vivo tissue structures. Methods of us are also featured.
FILED	Friday, May 11, 2012
APPL NO	14/116901
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) Original (OR) Class C12N 5/0062 (20130101) C12N 5/0671 (20130101) C12N 2513/00 (20130101) C12N 2531/00 (20130101) C12N 2533/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260041 — Methods for neural conversion of human embryonic stem cells

US 10260041	Chambers et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S)	MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
INVENTOR(S)	Stuart Chambers (San Francisco, California); Lorenz Studer (New York, New York)
ABSTRACT	The present invention relates generally to the field of cell biology of stem cells, more specifically the directed differentiation of pluripotent or multipotent stem cells, including human embryonic stem cells (hESC), somatic stem cells, and induced human pluripotent stem cells (hiPSC) using novel culture conditions. Specifically, methods are provided for obtaining neural tissue, floor plate cells, and placode including induction of neural plate development in hESCs for obtaining midbrain dopamine (DA) neurons, motorneurons, and sensory neurons. Further, neural plate tissue obtained using methods of the present inventions are contemplated for use in co-cultures with other tissues as inducers for shifting differentiation pathways, i.e. patterning.
FILED	Thursday, January 30, 2014
APPL NO	14/168835
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 2500/90 (20130101) C12N 2501/15 (20130101) C12N 2501/41 (20130101) C12N 2501/60 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2501/998 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260043 — Human extensively self-renewing erythroblasts (ESRE)

US 10260043	Palis et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	UNIVERSITY OF ROCHESTER (Rochester, New York)
ASSIGNEE(S)	UNIVERSITY OF ROCHESTER (Rochester, New York)
INVENTOR(S)	James Palis (Rochester, New York); Samantha England (Marseilles, France); Ah Ram Kim (Rochester, New York)
ABSTRACT	The present invention provides a human cell population that can self-renew extensively and yet retain the capacity to differentiate into red blood cells (RBCs). These cells are referred to as extensively self-renewing erythroblasts (ESREs). The cells of the invention serve among other things as a renewable source of transfusable RBCs.
FILED	Thursday, May 15, 2014
APPL NO	14/888110
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0641 (20130101) Original (OR) Class C12N 2500/36 (20130101) C12N 2500/90 (20130101) C12N 2501/14 (20130101) C12N 2501/33 (20130101) C12N 2501/39 (20130101) C12N 2501/125 (20130101) C12N 2506/02 (20130101) C12N 2510/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260045 — Use of collagen type VII for maintaining and re-inducing osteogenic abilities of mesenchymal stem cells

US 10260045	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Mei Chen (Altadena, California); David Woodley (Altadena, California)
ASSIGNEE(S)	University of Southern California (Los Angeles, California)
INVENTOR(S)	Mei Chen (Altadena, California); David Woodley (Altadena, California)
ABSTRACT	This invention provides methods of inducing and maintaining osteogenic potential in mesenchymal stem cells and compositions for doing the same. The compositions this invention comprise collagen 7 (C7), the NC1 domain of C7, or the 27 kD fragment of C7. Also provided are methods for treating bone diseases and correcting bone defects by applying compositions of this invention or by first priming ex vivo mesenchymal stem cells with compositions of this invention and then applying the primed mesenchymal stem cells to the patient. The invention further provides a mesenchymal stem cell osteogenesis induction kit.
FILED	Friday, July 30, 2010
APPL NO	13/388043
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0654 (20130101) Original (OR) Class C12N 2501/70 (20130101) C12N 2501/155 (20130101) C12N 2501/998 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260047 — Angiohematopoietic progenitor cells

US 10260047	Slukvin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Igor I. Slukvin (Verona, Wisconsin); Maksym A. Vodyanyk (Madison, Wisconsin); Kyung-Dal Choi (Falcon Heights, Minnesota)
ABSTRACT	A purified human cell population of subsets of angiohematopoietic progenitor cells, wherein the population is at least 94% pure and wherein the cells are selected with cell markers selected from the group of KDR, APLNR, VE-cadherin, PDGFRα, CD31, CD235a, CD73, CD43, and CD41a.
FILED	Tuesday, December 01, 2015
APPL NO	14/955760
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 5/0692 (20130101) Original (OR) Class C12N 2502/1394 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/5073 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260055 — Delivery of cargo proteins via ARRDC1-mediated microvesicles (ARMMs)

US 10260055	Lu et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Quan Lu (Newton, Massachusetts); Qiyu Wang (Boston, Massachusetts); Stanley N. Cohen (Palo Alto, California)
ABSTRACT	Methods, systems, compositions and strategies for the delivery of WW domain-containing fusion proteins into cells in vivo, ex vivo, or in vitro via ARMMs are provided. Methods, systems, compositions and strategies for the delivery of cargo proteins, such as transcription factors, tumor suppressors, developmental regulators, growth factors, metastasis suppressors, pro-apoptotic proteins, nucleases, recombinases, and reprogramming factors into cells in vivo, ex vivo, or in vitro via fusion to ARMM associated proteins (e.g., ARRDC1 or TSG101) are also provided.
FILED	Friday, November 10, 2017
APPL NO	15/809470
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) A61K 47/6455 (20170801) Peptides C07K 7/06 (20130101) C07K 14/4718 (20130101) C07K 2319/00 (20130101) C07K 2319/01 (20130101) C07K 2319/03 (20130101) C07K 2319/70 (20130101) C07K 2319/85 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class C12N 9/22 (20130101) C12N 9/93 (20130101) C12N 2810/85 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260065 — Random RNA libraries, methods of generating same, and screening methods utilizing same

US 10260065	Wilson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S)	Robert B. Wilson (Wynnewood, Pennsylvania); Yongping Wang (Wynnewood, Pennsylvania)
ABSTRACT	This invention provides sets and libraries of short hairpin ribonucleic acid (shRNA) molecules comprising a double-stranded region of random sequence containing random mismatches, methods of generating same, sets and libraries of expression vectors for same, methods of generating same, and methods for identifying an RNA therapeutic or RNA molecule that has an ability to affect a biological parameter, for identifying a drug target for a disease or disorder of interest, and for identifying a variant of an RNA molecule that has an altered ability to affect a biological parameter of interest.
FILED	Tuesday, August 05, 2014
APPL NO	14/910369
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/66 (20130101) C12N 15/1058 (20130101) C12N 15/1068 (20130101) Original (OR) Class C12N 15/1093 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260067 — Enhancing dermal wound healing by downregulating microRNA-26a

US 10260067	Feinberg
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Mark W. Feinberg (Newton, Massachusetts)
ABSTRACT	Methods for enhancing wound healing, e.g., in diabetic subjects, by administering an antagonist of miR-26a, e.g., an inhibitory nucleic acid that targets miR-26a.
FILED	Thursday, October 01, 2015
APPL NO	15/515927
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) A61K 31/712 (20130101) A61K 31/7105 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/141 (20130101) C12N 2310/3231 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260089 — Compositions and methods for recognition of RNA using triple helical peptide nucleic acids

US 10260089	Rozners et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	The Research Foundation for the State University of New York (Binghamton, New York)
ASSIGNEE(S)	The Research Foundation of The State University of New York (Binghamton, New York)
INVENTOR(S)	Eriks Rozners (Binghamton, New York); Thomas Zengeya (Frederick, Maryland)
ABSTRACT	Peptide nucleic acids containing thymidine and 2-aminopyridine (M) nucleobases formed stable and sequence selective triple helices with double stranded RNA at physiologically relevant conditions. The M-modified PNA displayed unique RNA selectivity by having two orders of magnitude higher affinity for the double stranded RNAs than for the same DNA sequences. Preliminary results suggested that nucleobase-modified PNA could bind and recognize double helical precursors of microRNAs.
FILED	Tuesday, October 29, 2013
APPL NO	14/066006
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Peptides C07K 7/08 (20130101) C07K 9/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6839 (20130101) Original (OR) Class C12Q 1/6839 (20130101) C12Q 2525/107 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260094 — DNA sequencing with non-fluorescent nucleotide reversible terminators and cleavable label modified nucleotide terminators

US 10260094	Ju et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	Jingyue Ju (Englewood Cliffs, New Jersey); Dae Hyun Kim (Northbrook, Illinois); Jia Guo (New York, New York); Qinglin Meng (Foster City, California); Zengmin Li (Flushing, New York); Huanyan Cao (Jiangyin, China PRC)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Jingyue Ju (Englewood Cliffs, New Jersey); Dae Hyun Kim (Northbrook, Illinois); Jia Guo (New York, New York); Qinglin Meng (Foster City, California); Zengmin Li (Flushing, New York); Huanyan Cao (Jiangyin, China PRC)
ABSTRACT	This invention provides a process for sequencing nucleic acids using 3′ modified deoxynucleotide analogs or 3′ modified deoxyinosine triphosphate analogs, and 3′ modified dideoxynucleotide analogs having a detectable marker attached to a base thereof.
FILED	Thursday, August 06, 2015
APPL NO	14/820254
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/70 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6876 (20130101) C12Q 2523/107 (20130101) C12Q 2523/319 (20130101) C12Q 2535/101 (20130101) C12Q 2535/113 (20130101) C12Q 2563/107 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260095 — Systems and methods for genetic and biological analysis

US 10260095	Esfandyarpour et al.
FUNDED BY	Department of Health and Human Services (HHS) Department of the Treasury (TREASURY) Internal Revenue Service (IRS)
APPLICANT(S)	GenapSys, Inc. (Redwood City, California)
ASSIGNEE(S)	GENAPSYS, INC. (Redwood City, California)
INVENTOR(S)	Hesaam Esfandyarpour (Redwood City, California); Kosar Baghbani Parizi (Redwood City, California); Mark F. Oldham (Emerald Hills, California); Eric S. Nordman (Palo Alto, California); Richard T. Reel (Hayward, California); Susanne Baumhueter (Redwood City, California); Cheryl Heiner (La Honda, California); Frank Lee (Irvine, California)
ABSTRACT	The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.
FILED	Wednesday, June 13, 2018
APPL NO	16/007829
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 2527/119 (20130101) C12Q 2527/119 (20130101) C12Q 2549/126 (20130101) C12Q 2563/116 (20130101) C12Q 2563/116 (20130101) C12Q 2565/607 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/327 (20130101) G01N 33/5438 (20130101) G01N 33/54313 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260096 — System and method for cleaning noisy genetic data and determining chromosome copy number

US 10260096	Rabinowitz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	Natera, Inc. (San Carlos, California)
ASSIGNEE(S)	Natera, Inc. (San Carlos, California)
INVENTOR(S)	Matthew Rabinowitz (San Francisco, California); Milena Banjevic (Los Altos Hills, California); Zachary Demko (San Francisco, California); David Johnson (San Francisco, California); Dusan Kijacic (Los Altos Hills, California); Dimitri Petrov (Stanford, California); Joshua Sweetkind-Singer (San Jose, California); Jing Xu (Jersey City, New Jersey)
ABSTRACT	Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment, the chromosome copy number can be determined from the measured genetic data, with or without genetic information from one or both parents.
FILED	Wednesday, March 01, 2017
APPL NO	15/446778
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6848 (20130101) C12Q 1/6851 (20130101) C12Q 1/6855 (20130101) C12Q 1/6855 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 2525/155 (20130101) C12Q 2535/122 (20130101) C12Q 2537/16 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Electric Digital Data Processing G06F 19/18 (20130101) G06F 19/24 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260098 — FIG4 gene mutations in neurodegeneration

US 10260098	Meisler
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Miriam Meisler (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Miriam Meisler (Ann Arbor, Michigan)
ABSTRACT	The present invention relates to neurological disease, in particular to mutations in the FIG4 gene. The present invention also provides assays for the detection of variant FIG4 alleles, and assays for detecting FIG4 polymorphisms and mutations associated with disease states such as ALS.
FILED	Friday, March 06, 2009
APPL NO	12/399490
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/136 (20130101) C12Q 2600/156 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260099 — Compositions and methods for diagnosis and treatment of epilepsy

US 10260099	Delgado-Escueta et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); RIKEN (Saitama, Japan); INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ (Delegacion Tlalpan, Mexico); THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S)	Antonio V. Delgado-Escueta (Malibu, California); Kazuhiro Yamakawa (Saitama, Japan); Toshimitsu Suzuki (Saitama, Japan); Marco Tulio Medina-Hernandez (Tegucigalpa, Honduras); Maria Elisa Alonso Vilatela (Delegacion Coyoacan, Mexico)
ABSTRACT	Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.
FILED	Tuesday, November 24, 2015
APPL NO	14/951407
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) Peptides C07K 16/18 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260100 — FIG4 gene mutations in neurodegeneration

US 10260100	Meisler et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); Baylor College of Medicine (Houston, Texas)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); BAYLOR COLLEGE OF MEDICINE (Houston, Texas)
INVENTOR(S)	Miriam Meisler (Ann Arbor, Michigan); James R. Lupski (Houston, Texas); Clement Chow (Ann Arbor, Michigan)
ABSTRACT	The present invention relates to neuropathy, in particular to mutations in the FIG4 gene. The present invention also provides assays for the detection of variant FIG4 alleles, and assays for detecting FIG4 polymorphisms and mutations associated with disease states.
FILED	Thursday, May 12, 2016
APPL NO	15/152608
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/172 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/10 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260101 — C-kit oncogene mutations in melanoma

US 10260101	Bastian et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Boris C. Bastian (Mill Valley, California); John A. Curtin (Manchester, United Kingdom)
ABSTRACT	The present invention provides methods of detecting c-KIT-dependent-melanoma for diagnostic and prognostic purposes. The invention further provides methods of treating such melanoma by inhibiting c-KIT.
FILED	Wednesday, October 16, 2013
APPL NO	14/055752
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260105 — MiR-320e and colorectal cancer

US 10260105	Goel et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	BAYLOR RESEARCH INSTITUTE (Dallas, Texas)
ASSIGNEE(S)	Baylor Research Institute (Dallas, Texas)
INVENTOR(S)	Ajay Goel (Dallas, Texas); Lucia Perez-Carbonell (Dallas, Texas); C. Richard Boland (Dallas, Texas)
ABSTRACT	Embodiments provide methods and compositions related to determining treatments for colorectal cancer patients by detection and analysis of the expression level of miRNA such as miR-320e in the patients. Embodiments provide predictive, prognostic and/or diagnostics methods by identifying miRNAs that are useful for clinical management of cancer patients, particularly colorectal cancer patients or patients at risk or determined to have colorectal cancer. Methods and compositions are based, in part, on the discovery that expression of certain miRNAs in cancer patients is associated with advancing cancer stages and/or can predict the responsiveness of cancer therapy, and can, therefore, provide basis for designing treatment strategies. In particular embodiments, the miRNA molecule is miR-320, particularly miR-320e.
FILED	Wednesday, February 18, 2015
APPL NO	15/120052
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/513 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2320/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 40/63 (20180101) Technologies for Adaptation to Climate Change Y02A 90/22 (20180101) Y02A 90/26 (20180101)
VIEW PATENT	@ USPTO: Full Text PDF

10260106 — Methods and compositions for identification of prostate cancer markers

US 10260106	Reddy et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	HENRY FORD HEALTH SYSTEM (Detroit, Michigan)
ASSIGNEE(S)	Henry Ford Health System (Detroit, Michigan)
INVENTOR(S)	G. Prem-Veer Reddy (West Bloomfield, Michigan); Mani Menon (Bloomfield, Michigan)
ABSTRACT	A method for diagnosing and treating prostate cancer in a human subject is provided, the method comprises: a. providing a sample of prostate tissue, blood, or urine from the subject; b. determining the level of expression of SEQ ID NO: 1 and the expression of SEQ ID NO: 5 in the sample, wherein an increased level of expression of SEQ ID NO:1 and a reduced level of expression of SEQ ID NO: 5 in the sample is indicative of a diagnosis that the subject has prostate cancer; and c. administering a therapeutically effective prostate cancer treatment selected from the group consisting of an androgen receptor (AR)-targeted therapy, an antimicrotubule agent, an alkylating agent and an anthracenedione to the subject to treat the prostate cancer in the human subject diagnosed with prostate cancer.
FILED	Friday, July 22, 2016
APPL NO	15/217440
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/09 (20130101) A61K 31/15 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260108 — PARP genomic variants conferring resistance and sensitization to chemotherapy under inhibition

US 10260108	Tawbi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S)	Hussein A. Tawbi (Pittsburgh, Pennsylvania); Petr Pancoska (Pittsburgh, Pennsylvania); Panagiotis Benos (Pittsburgh, Pennsylvania); Marjorie Romkes (San Diego, California); Andrew J. Sedgewick (Brooklyn, New York); Irina Abecassis (Pittsburgh, Pennsylvania)
ABSTRACT	A method is provided for selecting a subject diagnosed with cancer as a candidate for treatment with a PARP1 inhibitor, or both a PARP1 inhibitor and a chemotherapeutic agent such as an alkylating agent. The method includes detecting the presence or absence of a mutation in a non-coding region of a PARP1 gene, wherein the presence of a mutation in the PARP1 gene indicates that the cancer can be treated with the PARP1 inhibitor, optionally in conjunction with the chemotherapeutic agent. In a specific, non-limiting example, the PARP1 inhibitor is verliparib (ABT-888).
FILED	Friday, October 30, 2015
APPL NO	15/524242
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) A61K 31/4184 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261013 — Robust interferometer and methods of using same

US 10261013	Bornhop et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Darryl J. Bornhop (Nashville, Tennessee); Michael Kammer (Nashville, Tennessee)
ABSTRACT	Provided are improved optical detection systems and methods for using same, which systems and methods comprise single channel interferometric detection systems and methods for determining a characteristic property of samples. Such interferometric detection systems and methods employ a light beam that impinges two or more discrete zones along a channel, thereby avoiding variations that can result in increases in detection limits and/or measurement errors.
FILED	Thursday, June 30, 2016
APPL NO	15/199417
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/45 (20130101) Original (OR) Class G01N 21/75 (20130101) G01N 2021/458 (20130101) G01N 2201/06113 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261065 — Nanofluidic devices with integrated components for the controlled capture, trapping, and transport of macromolecules and related methods of analysis

US 10261065	Ramsey et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	John Michael Ramsey (Chapel Hill, North Carolina); Laurent Menard (Cary, North Carolina)
ABSTRACT	Devices for controlling the capture, trapping, and transport of macromolecules include at least one fluidic transport nanochannel that intersects and is in fluid communication with at least one transverse nanochannel with (shallow) regions and/or with integrated transverse electrodes that enable fine control of molecule transport dynamics and facilitates analyses of interest, e.g., molecular identification, length determination, localized (probe) mapping and the like.
FILED	Wednesday, February 26, 2014
APPL NO	14/190520
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502761 (20130101) B01L 2200/0663 (20130101) B01L 2300/0896 (20130101) B01L 2400/0415 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44791 (20130101) G01N 33/48721 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10261068 — Persevere-II: redefining the pediatric sepsis biomarker risk model with septic shock phenotype

US 10261068	Wong
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio)
ASSIGNEE(S)	CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio)
INVENTOR(S)	Hector R. Wong (Cincinnati, Ohio)
ABSTRACT	The methods disclosed herein relate to an improved tool incorporating platelet count into a multi-biomarker based outcome risk stratification model for evaluating mortality risk in pediatric patients having sepsis. The methods described here are useful for treating sepsis, for point of care clinical decision support, for stratifying septic shock patients based on baseline mortality risk, and for clinical trial design, among other uses.
FILED	Thursday, June 02, 2016
APPL NO	15/171418
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/1698 (20130101) A61M 1/3496 (20130101) A61M 1/3666 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/49 (20130101) Original (OR) Class G01N 33/5094 (20130101) G01N 2333/47 (20130101) G01N 2333/523 (20130101) G01N 2333/5421 (20130101) G01N 2333/96436 (20130101) G01N 2333/96494 (20130101) G01N 2800/26 (20130101) G01N 2800/56 (20130101) G01N 2800/60 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261073 — Compartmentalized integrated biochips

US 10261073	Bechstein et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Daniel Jacob Benjamin Bechstein (Mountain View, California); Shan X. Wang (Portola Valley, California)
ABSTRACT	An integrated microfluidic biochip is provided that includes a microfluidic device, where the microfluidic device includes hollow structures, where at least one the hollow structure includes an output at a bottom surface of the microfluidic device, and a sensor plate, where the sensor plate comprises a plurality of independent surface sensors, where the microfluidic device is sealably attachable to the sensor plate, where the hollow structure output abuts the surface sensor when the microfluidic device is attached to the sensor plate.
FILED	Friday, October 04, 2013
APPL NO	14/046605
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 2200/12 (20130101) B01L 2200/16 (20130101) B01L 2200/0689 (20130101) B01L 2300/0636 (20130101) B01L 2300/0816 (20130101) B01L 2300/0883 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5302 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10261074 — Oxidase activity of polymeric coated cerium oxide nano-particles

US 10261074	Perez et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S)	Jesus Manuel Perez (Orlando, Florida); Atul Asati (Oviedo, Florida); Santimukul Santra (Orlando, Florida); Charalambos Kaittanis (Oviedo, Florida); Sudip Nath (Kolkata, India)
ABSTRACT	Methods, systems, compositions include biocompatible polymer coated nanoceria that function as aqueous redox catalyst with enhanced activity at an acidic to moderately alkaline pH value between 1 and 8. The compositions are used as oxidizing agents for decomposition, decontamination or inactivation of organic contaminants, such as, pesticides and chemical warfare agents. Another use includes nanoceria as targetable nanocatalyst prepared by conjugating various targeting ligands to the nanoparticle coating to form a colorimetric or fluorescent probe in immunoassays and other molecule binding assays that involve the use of a molecule in solution that changes the color of the solution or emits a fluorescent signal, where localization of nanoceria to organs or tissue is assessed by treatment with an oxidation sensitive dye or other detection devices. Versatility and uses of the nanoceria compositions are controlled by pH value, choice of dye substrate and thickness of the polymer coating on the ceria nanoparticles.
FILED	Monday, November 10, 2014
APPL NO	14/537102
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/26 (20130101) B01J 2231/005 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/587 (20130101) G01N 33/54346 (20130101) Original (OR) Class G01N 33/57423 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261081 — Low density microarrays for vaccine related protein quantification, potency determination and efficacy evaluation

US 10261081	Rowlen
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Kathy L. Rowlen (Boulder, Colorado)
ASSIGNEE(S)	INDEVR, INC. (Boulder, Colorado)
INVENTOR(S)	Kathy L. Rowlen (Boulder, Colorado)
ABSTRACT	Methods for the quantification of influenza HA proteins and anti-influenza antibodies for the fields of vaccine-related protein quantification, potency determination, and efficacy evaluation are provided. According to the technology, quantification is achieved by providing capture agents attached to an array in a series of decreasing concentrations. Serial dilutions of a reference material also may be introduced. The reference material within each solution binds to the capture agents on the array and is labeled with a label agent capable of producing a detectable signal used to construct a calibration curve. A target material of unknown concentration is introduced to a separate identical array, and the target material binds to the capture agents and also is labeled by a label agent to produce a detectable signal. The calibration curve based on the reference material is then utilized to determine the concentration of the target material without the need to perform replicate experiments.
FILED	Tuesday, June 12, 2012
APPL NO	13/494802
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) G01N 33/56983 (20130101) Original (OR) Class G01N 2333/11 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261084 — Activated GTPase-based assays and kits for the diagnosis of sepsis and other infections

US 10261084	Buranda et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)	STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S)	Tione Buranda (Albuquerque, New Mexico); Jacob Ongudi Agola (Albuquerque, New Mexico); Soumik BasuRay (Dallas, Texas); Scarlett Swanson (Albuquerque, New Mexico); Angela Wandinger-Ness (Albuquerque, New Mexico); Peter C. Simons (Albuquerque, New Mexico); Virginie Bondu (Albuquerque, New Mexico)
ABSTRACT	In one embodiment, the invention provides a method of diagnosing sepsis or a virus-related infection (often a viral hemorrhagic fever infection) in a subject by detecting and measuring the level of a set of sepsis and virus infection-associated-GTPase biomarkers in a sample obtained from the subject using multiplexed flow cytometry. Related kits are also provided. In a preferred embodiment, the invention provides point of care diagnostic methods for determining an early stage sepsis or the severity of a virus infection, especially in a hospital or other setting.
FILED	Thursday, February 19, 2015
APPL NO	14/626536
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/86 (20130101) G01N 33/573 (20130101) Original (OR) Class G01N 2333/914 (20130101) G01N 2800/26 (20130101) G01N 2800/224 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261098 — Biomarkers for diagnosis and management of neuro-immunological diseases

US 10261098	Bielekova et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Montana State University (Bozeman, Montana)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Montana State University (Bozeman, Montana)
INVENTOR(S)	Bibiana Bielekova (Kensington, Maryland); Mika Komori (North Bethesda, Maryland); Peter Kosa (Bethesda, Maryland); Mark C. Greenwood (Bozeman, Montana); Christopher Barbour (Bozeman, Montana)
ABSTRACT	Biomarkers associated with neuroimmunological disease are described. The disclosed biomarkers are secreted proteins identified in cerebral spinal fluid (CSF) samples of patients with neurological disease. The disclosed biomarkers identify patients with intrathecal inflammation, distinguish multiple sclerosis (MS) patients from patients with other types of inflammatory neurological diseases and from subjects without MS, distinguish progressive MS patients from patients with relapsing-remitting MS, identify subjects with non-MS inflammatory neurological diseases, differentiate healthy subjects from patients with any type of neurological disease, and/or identify subjects with increased disability, CNS tissue damage and/or neurodegeneration. Process-specific biomarkers that can be used in place of a brain biopsy to identify immune cell infiltration and/or activation in the CNS are also described. Methods of treating subject with neurological disease, and methods of evaluating the efficacy of particular treatments, based on detection of the disclosed biomarkers are also described.
FILED	Monday, August 17, 2015
APPL NO	15/504438
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2333/705 (20130101) G01N 2800/52 (20130101) G01N 2800/60 (20130101) G01N 2800/285 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261151 — Systems and methods for assessing pulmonary gas transfer using hyperpolarized ¹²⁹Xe MRI

US 10261151	Driehuys et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) Biomedical Technology Resource Center (BTRC) National Cancer Institute (NCI) National Center for Research Resources (NCRR) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Duke University (Durham, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Bastiaan Driehuys (Chapel Hill, North Carolina); Gary Price Cofer (Hillsborough, North Carolina)
ABSTRACT	Methods and systems for assessing pulmonary gas exchange and/or alveolar-capillary barrier status include obtaining at least one MRI image and/or image data of ¹²⁹Xe dissolved in the red blood cells (RBC) in the gas exchange regions of the lungs of a patient. The image is sufficiently sensitive to allow a clinician or image recognition program to assess at least one of pulmonary gas exchange, barrier thickness or barrier function based on the ¹²⁹Xe MRI RBC image.
FILED	Thursday, March 02, 2017
APPL NO	15/447321
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/08 (20130101) A61B 5/055 (20130101) A61B 5/416 (20130101) A61B 5/1075 (20130101) A61B 5/4887 (20130101) A61B 5/7239 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/08 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/465 (20130101) G01R 33/483 (20130101) Original (OR) Class G01R 33/4816 (20130101) G01R 33/5601 (20130101) G01R 33/34076 (20130101) G01R 33/56341 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261152 — System and method for confounder-corrected T1 measures using MRI

US 10261152	Reeder et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Scott B. Reeder (Middleton, Wisconsin); Xiaoke Wang (Madison, Wisconsin); Diego Hernando (Madison, Wisconsin)
ABSTRACT	A system and method are provided for determining B1 inhomogeneities or creating a T1 map of a subject using a magnetic resonance imaging (MRI) system that is corrected for an influence of a presence of fat and a presence of iron in the subject on T1 weighting. The method includes controlling the MRI system using a single pulse sequence to acquire, from the subject, a plurality of datasets with varied T1 weighting created by varying at least one of a repetition time (TR) and a flip angle (FA) for repetitions of the single pulse sequence. The method also includes using an MR signal model and the plurality of datasets, estimating B1 inhomogeneities or generating a T1 map of the subject that is corrected for an influence of a presence of fat and a presence of iron in the subject on T1 weighting in the plurality of datasets.
FILED	Wednesday, March 22, 2017
APPL NO	15/466646
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/543 (20130101) Original (OR) Class G01R 33/5608 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261154 — Nuclear magnetic resonance (NMR) fingerprinting tissue classification and image segmentation

US 10261154	Griswold et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Mark Griswold (Shaker Heights, Ohio); Yun Jiang (Cleveland Heights, Ohio); Dan Ma (Cleveland, Ohio); Anagha Deshmane (Cleveland Heights, Ohio); Chaitra Badve (Cleveland Heights, Ohio); Vikas Gulani (Shaker Heights, Ohio); Jeffrey L Sunshine (Pepper Pike, Ohio)
ABSTRACT	Apparatus, methods, and other embodiments associated with NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals, and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals. The NMR signal evolution may be assigned to a cluster based on the characterization of the resonant species. Cluster overlay maps may be produced simultaneously based, at least in part, on the clustering. The clusters may be associated with different tissue types.
FILED	Monday, April 21, 2014
APPL NO	14/257081
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/4828 (20130101) G01R 33/5608 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10261161 — Phantom for quantitative diffusion magnetic resonance imaging

US 10261161	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Xiaoke Wang (Madison, Wisconsin); Scott Brian Reeder (Middleton, Wisconsin); Diego Hernando (Madison, Wisconsin)
ABSTRACT	A phantom for use with magnetic resonance imaging (“MRI”) and, in particular, for calibrating quantitative diffusion MRI is provided. In general, the phantom includes a solution composed of a solvent that has diffusivity value higher than that of water, and a solute that when added to the solvent reduces the diffusivity of the solution. By varying the combined concentration of the solvent and solute, the diffusivity of the solution can be controlled to fall within a range of diffusivity values found in biological tissues in a variety of different physiological conditions or tissue environments.
FILED	Monday, June 15, 2015
APPL NO	14/739554
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/58 (20130101) Original (OR) Class G01R 33/56341 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261298 — Near-infrared-II confocal microscope and methods of use

US 10261298	Hong et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Guosong Hong (Somerville, Massachusetts); Alexander Antaris (Stanford, California); Shuo Diao (Jilin, China PRC); Hongjie Dai (Cupertino, California)
ABSTRACT	Disclosed are methods and devices for confocal microscopy in the near-infrared. wavelength. The device uses a near-infrared (NIR) light producing source such as laser; optical components designed to reflect and transmit NIR from a sample; and an NIR detector coupled to a computer for constructing a focal plane image from a raster scan. The detector may be a photodiode or photo-multiplier tube for detecting fluorescence signals in the NIR (800-1700 nm) wavelength range using a variety of NIR-I (800-1000 nm) and NIR-II (1000-1700 nm) dyes and nanomaterials. An imaging method is described using the NIR-confocal microscope for slice by slice 3D imaging of biological tissues throughout a thickness up to, for example, 5 mm in the NIR-II window. The reduced scattering in NIR-II allows for tissue penetration up to about 5-10 mm, superior to ˜0.2 mm afforded by conventional imaging.
FILED	Tuesday, December 08, 2015
APPL NO	14/962988
ART UNIT	2872 — Optics
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 2021/6439 (20130101) G01N 2223/509 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0036 (20130101) G02B 21/0076 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10262104 — HLA typing using selective amplification and sequencing

US 10262104	Royce et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) U.S. Public Health Service (USPHS)
APPLICANT(S)	Illumina, Inc. (San Diego, California)
ASSIGNEE(S)	ILLUMINA, INC. (San Diego, California)
INVENTOR(S)	Thomas Royce (San Diego, California); Craig April (La Jolla, California); Fiona Kaper (Encinitas, California); Jian-Bing Fan (San Diego, California)
ABSTRACT	Presented herein are methods and compositions for determining haplotypes in a sample. The methods are useful for obtaining sequence information regarding, for example, HLA type and haplotype. Also presented herein are methods of determining haplotypes in a sample based on a plurality sequence reads.
FILED	Thursday, October 08, 2015
APPL NO	14/878830
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 1/6874 (20130101) C12Q 1/6881 (20130101) C12Q 1/6883 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2600/172 (20130101) Electric Digital Data Processing G06F 19/16 (20130101) G06F 19/22 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10263394 — Widely tunable swept source

US 10263394	Jayaraman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Eye Institute (NEI)
APPLICANT(S)	Praevium Research, Inc. (Santa Barbara, California); Thorlabs, Inc. (Newton, New Jersey)
ASSIGNEE(S)	Praevium Research, Inc. (Santa Barbara, California); Thorlabs, Inc. (Newton, New Jersey)
INVENTOR(S)	Vijaysekhar Jayaraman (Goleta, California); Christopher Burgner (Santa Barbara, California); Demis John (Goleta, California); Peter Heim (Jessup, Maryland); Alex Ezra Cable (Newton, New Jersey)
ABSTRACT	A high-speed, single-mode, high power, reliable and manufacturable wavelength-tunable light source operative to emit wavelength tunable radiation over a wavelength range contained in a wavelength span between about 950 nm and about 1150 nm, including a vertical cavity laser (VCL), the VCL having a gain region with at least one compressively strained quantum well containing Indium, Gallium, and Arsenic.
FILED	Tuesday, August 22, 2017
APPL NO	15/683435
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0059 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02091 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/2059 (20130101) H01S 5/3095 (20130101) H01S 5/18308 (20130101) H01S 5/18311 (20130101) H01S 5/18341 (20130101) H01S 5/18366 (20130101) Original (OR) Class H01S 5/18369 (20130101) H01S 5/18372 (20130101) H01S 5/18377 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Defense (DOD)

10258027 — Autodissemination of an insect-growth regulator for insect management

US 10258027	Gaugler et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) Small Business Administration (SBA) Small Business Innovation Research (SBIR) Department of Agriculture (USDA) Agricultural Research Service (ARS)
APPLICANT(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S)	Randy Gaugler (North Brunswick, New Jersey); Devi Suman (New Brunswick, New Jersey); Yi Wang (South River, New Jersey)
ABSTRACT	The described invention provides a gel formulation of a composition comprising at least one insecticide in an amount effective to control an insect larval population, an apparatus for autodissmenination of an insecticide for insect management containing (1) a reservoir (2) a transfer plate and cover, and (3) a mesh component, a method and a system for autodissemination for effectively controlling an insect larval population. Also disclosed is an improvided biphasic autodissemination station for control of undesirable insect populations.
FILED	Monday, February 22, 2016
APPL NO	15/050439
ART UNIT	3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/02 (20130101) A01M 1/20 (20130101) A01M 1/2005 (20130101) Original (OR) Class A01M 1/2011 (20130101) A01M 1/2016 (20130101) A01M 2200/011 (20130101) A01M 2200/012 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/00 (20130101) A01N 25/00 (20130101) A01N 25/04 (20130101) A01N 25/04 (20130101) A01N 25/04 (20130101) A01N 25/24 (20130101) A01N 25/24 (20130101) A01N 25/24 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258259 — Multimodal sensory feedback system and method for treatment and assessment of disequilibrium, balance and motion disorders

US 10258259	Zets et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Gary Zets (Maitland, Florida); Bruce Mortimer (Maitland, Florida); Gregory R. Mort (Altamonte Springs, Florida)
ASSIGNEE(S)
INVENTOR(S)	Gary Zets (Maitland, Florida); Bruce Mortimer (Maitland, Florida); Gregory R. Mort (Altamonte Springs, Florida)
ABSTRACT	The invention relates to a system and method for measuring the biomechanical state of a subject using various sensors simultaneously with providing the subject with visual exercises for rehabilitation and assessment of disequilibrium, balance and motion disorders. The biomechanical state of a subject is measured during the subject's performance of a predetermined task. Such measurements are useful for the assessment of disequilibrium, balance and motion disorders and are also useful for the determination of therapeutic application of vibrotactile, auditory, or visual feedback to a subject during the subject's attempt to perform a predetermined task. An intelligent controller compares the subject's biomechanical state to a predetermined parameter to determine a variance. If the variance exceeds a threshold, feedback in the form of visual feedback, vibrotactile feedback or auditory feedback may be provided to the subject as a therapeutic means for enabling the subject to compensate for disorder effects.
FILED	Tuesday, November 29, 2011
APPL NO	13/306872
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/1124 (20130101) Original (OR) Class Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258268 — High-speed tissue oximetry system employing fast digital diffuse optical spectroscopy

US 10258268	Roblyer et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S)	Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S)	Darren Roblyer (Boston, Massachusetts); Alyssa Torjesen (Charlestown, Massachusetts)
ABSTRACT	A tissue oximetry system employing diffuse optical spectroscopy includes an optical subsystem and an electronics and processing subsystem, together generating modulated optical signals processing a response optical signal in order to obtain measurements of blood oxygen values for a tissue from per-wavelength absorption values. Signal sources generate RF modulation signals, and ADC circuitry generates streams of digital sample values from analog detection signals. Data acquisition circuitry and a processor (1) provide RF modulation command values in synchronism with sampling operation according to an offset pattern and rate, stepping through an RF range to obtain measurements of the absorption values in measurement intervals at least 10 times per second, (2) in each of the measurement intervals, calculate the model to obtain the blood oxygen values from the measurements of the absorption values, and display or otherwise use the obtained blood oxygen values in higher-level diagnostic assessment of tissue blood oxygenation.
FILED	Tuesday, April 24, 2018
APPL NO	15/960747
ART UNIT	3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/742 (20130101) A61B 5/1495 (20130101) A61B 5/7203 (20130101) A61B 5/14551 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10258292 — Method and apparatus for predicting a need for a blood transfusion

US 10258292	Hu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Fu-Ming Hu (Ellicott City, Maryland); Colin Mackenzie (Pasadena, Maryland); Shiming Yang (Halethrope, Maryland); Hegang Chen (Ellicott City, Maryland)
ASSIGNEE(S)	University of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S)	Fu-Ming Hu (Ellicott City, Maryland); Colin Mackenzie (Pasadena, Maryland); Shiming Yang (Halethrope, Maryland); Hegang Chen (Ellicott City, Maryland)
ABSTRACT	A method is provided for predicting that a patient will require a blood transfusion during a treatment. The method includes obtaining, on a processor, first data that indicates values for one or more parameters of a characteristic of a continuous photoplethysmographic (PPG) waveform collected during the treatment. The method further includes applying, on the processor, coefficients to the values for the one or more parameters. The method further includes determining, on the processor, second data that indicates a prediction that the patient will require the blood transfusion during the treatment based on applying the coefficients to the values for the one or more parameters. An apparatus is also provided for predicting that the patient will require the blood transfusion during the treatment.
FILED	Tuesday, August 12, 2014
APPL NO	14/911421
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0205 (20130101) A61B 5/742 (20130101) A61B 5/02042 (20130101) A61B 5/02416 (20130101) A61B 5/4836 (20130101) A61B 5/7275 (20130101) Original (OR) Class A61B 5/14551 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) G06F 19/3481 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101)
VIEW PATENT	@ USPTO: Full Text PDF

10258615 — Methods of treating a neurodegenerative disease in a mammal in need thereof

US 10258615	Trotti et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Thomas Jefferson University (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Thomas Jefferson University (Philadelphia, Pennsylvania)
INVENTOR(S)	Davide Trotti (Bala Cynwyd, Pennsylvania); Piera Pasinelli (Bala Cynwyd, Pennsylvania); Michael R. Jablonski (Philadelphia, Pennsylvania)
ABSTRACT	The present invention provides a method of treating or ameliorating a neurodegenerative disease in a mammal, the method comprising administering to the mammal a therapeutically effective amount of a neurodegenerative disease drug, wherein the drug is a substrate of an ABC transporter inhibitor, wherein the mammal is further administered a therapeutically effective amount of an ABC transporter inhibitor, whereby the neurodegenerative disease is treated in the mammal. In certain embodiments, the neurodegenerative disease comprises at least one selected from the group consisting of spinal cord injury, Alzheimer's disease, Parkinson's disease, Huntington's disease, prion disease, amyotrophic lateral sclerosis, a tauopathy, and chronic traumatic encephalopathy.
FILED	Tuesday, December 09, 2014
APPL NO	15/103234
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/55 (20130101) A61K 31/428 (20130101) A61K 31/428 (20130101) A61K 31/473 (20130101) Original (OR) Class A61K 31/473 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/4725 (20130101) A61K 31/4725 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259120 — Compact resolver pre-amplification assembly (RPA) module

US 10259120	Rossland et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Eric Rossland (Alexandria, Virginia); Mark Fratta (Harwood, Maryland); Greg Levanas (Costa Mesa, California)
ABSTRACT	A compact resolver pre-amplification assembly has first and second printed circuit boards. The boards include an interface with an N/N−1 resolver and a resolver-to-digital converter and three signal paths. The first and second circuit boards are contained in a single package configured for mounting on a robotic joint while providing high amplification and noise rejection. Low level sensitive signal are separated from high level excite signals by locating sensitive signals on the first board and excite signals on the second board.
FILED	Thursday, May 12, 2016
APPL NO	15/153413
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 13/088 (20130101) Original (OR) Class Coding; Decoding; Code Conversion in General H03M 1/485 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259539 — Portable lightweight apparatus for transferring heavy loads

US 10259539	Galway et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Robert J. Galway (Virginia Beach, Virginia); Daniel J. Galway (Virginia Beach, Virginia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Robert J. Galway (Virginia Beach, Virginia); Daniel J. Galway (Virginia Beach, Virginia)
ABSTRACT	A method and apparatus for the water-based transfer of heavy loads. The invention is a lightweight apparatus is reconfigurable, and it includes a gantry arrangement mounted on beams or a platform and the apparatus is used to transfer heavy load items. The apparatus reconfigurable and may be used in a water-based loading environments in performing a variety of loading functions in situations involving one or more watercrafts and/or a pier or the like.
FILED	Thursday, May 12, 2016
APPL NO	15/153023
ART UNIT	3654 — Material and Article Handling
CURRENT CPC	Ships or Other Waterborne Vessels; Equipment for Shipping B63B 7/00 (20130101) B63B 27/30 (20130101) Original (OR) Class Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 67/62 (20130101) B65G 2814/0397 (20130101) Cranes; Load-engaging Elements or Devices for Cranes, Capstans, Winches, or Tackles B66C 23/36 (20130101) B66C 23/52 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259592 — Aircraft receptacle

US 10259592	Lewis et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Life Cycle Management Center (AFLCMC)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Brian Lewis (Seattle, Washington); Paul William Klenke (Seattle, Washington); Dennis P. Byrne (Poulsbo, Washington); Ky Huu Nguyen (Garden Grove, California); Paul Gerard Weber (Issaquah, Washington)
ABSTRACT	A system and method for an aircraft refueling receptacle. The aircraft refueling receptacle comprises a pedestal, a flanged structure, a sliding valve, and a bolt. The flanged structure has a first ledge, a second ledge, and a number of flanges extending inwardly. The pedestal contacts the first ledge. The sliding valve has a first face that contacts the second ledge of the flanged structure during refueling. The bolt extends a part of a length of the pedestal and is connected to a receiver within the pedestal.
FILED	Monday, March 02, 2015
APPL NO	14/635657
ART UNIT	3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 37/16 (20130101) B64D 39/06 (20130101) Original (OR) Class Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/40 (20170101)
VIEW PATENT	@ USPTO: Full Text PDF

10259844 — Endometriosis cell targeting peptide and uses thereof

US 10259844	Fukuda et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Sanford-Burnham Medical Research Institute (LaJolla, California); Keio University (Tokyo, Japan); Noriko Nozawa (, None)
ASSIGNEE(S)	Sanford-Burnham Medical Research Institute (La Jolla, California)
INVENTOR(S)	Michiko Fukuda (LaJolla, California); Daisuke Aoki (Shinjuku-ku, Japan); Shiro Nozawa (Shibuya-ku, Japan)
ABSTRACT	Provided herein are compositions and methods for selectively targeting an endometriosis cell.
FILED	Friday, April 10, 2015
APPL NO	14/683520
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/7028 (20130101) A61K 38/08 (20130101) A61K 38/08 (20130101) A61K 45/06 (20130101) A61K 47/64 (20170801) A61K 49/0056 (20130101) A61K 2300/00 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Original (OR) Class C07K 14/001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) G01N 2800/364 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259849 — Isolated B7-H4 specific compositions and methods of use thereof

US 10259849	Scholler et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Nathalie Scholler (Mountain View, California); Denarda Dangaj (Vaud, Switzerland); Aizhi Zhao (Wallingford, Pennsylvania); Daniel J. Powell (Bala Cynwood, Pennsylvania)
ABSTRACT	The present invention relates to B7-H4-specific compositions and methods of use thereof.
FILED	Thursday, January 28, 2016
APPL NO	15/009082
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/47 (20130101) Original (OR) Class C07K 14/70532 (20130101) C07K 16/18 (20130101) C07K 16/2827 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/6863 (20130101) G01N 33/57492 (20130101) G01N 2333/70532 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260054 — Engineered organophosphorus acid anhydrolases and methods of use thereof

US 10260054	Pegan et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	University of Georgia Research Foundation, Inc. (Athens, Georgia); The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	University of Georgia Research Foundation, Inc. (Athens, Georgia); The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Scott Pegan (Athens, Georgia); Steven P. Harvey (Lutherville, Maryland)
ABSTRACT	Genetically engineered organophosphorus acid anhydrolases (OPAA) with improved catalytic efficiency and relaxed stereospecificity are provided. The variants typically include a mutation at the residue corresponding to H343 of wildtype Alteromonas sp. OPAA. The mutation allows the OPAA enzyme to effectively process both VR enantiomers. The OPAA optionally include one or more mutations selected the residues corresponding to Y212, V342, and I215 of wildtype Alteromonas sp. OPAA which improve the enzyme's catalytic efficiency for VX and VR. A particularly preferred OPAA includes mutations at the residues corresponding Y212F, V342L, I215Y, and H343D relative to wildtype Alteromonas sp. OPAA. Compositions including an effective amount of OPAA to increase hydrolysis of an organophosphate, and methods of use thereof for treating subjects exposed to an organophosphate, or a surface or liquid contaminated with an organophosphate are also provided.
FILED	Monday, June 06, 2016
APPL NO	15/174719
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/46 (20130101) A61K 31/46 (20130101) A61K 31/4425 (20130101) A61K 31/4425 (20130101) A61K 31/5513 (20130101) A61K 31/5513 (20130101) A61K 38/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/08002 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260055 — Delivery of cargo proteins via ARRDC1-mediated microvesicles (ARMMs)

US 10260055	Lu et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Quan Lu (Newton, Massachusetts); Qiyu Wang (Boston, Massachusetts); Stanley N. Cohen (Palo Alto, California)
ABSTRACT	Methods, systems, compositions and strategies for the delivery of WW domain-containing fusion proteins into cells in vivo, ex vivo, or in vitro via ARMMs are provided. Methods, systems, compositions and strategies for the delivery of cargo proteins, such as transcription factors, tumor suppressors, developmental regulators, growth factors, metastasis suppressors, pro-apoptotic proteins, nucleases, recombinases, and reprogramming factors into cells in vivo, ex vivo, or in vitro via fusion to ARMM associated proteins (e.g., ARRDC1 or TSG101) are also provided.
FILED	Friday, November 10, 2017
APPL NO	15/809470
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) A61K 47/6455 (20170801) Peptides C07K 7/06 (20130101) C07K 14/4718 (20130101) C07K 2319/00 (20130101) C07K 2319/01 (20130101) C07K 2319/03 (20130101) C07K 2319/70 (20130101) C07K 2319/85 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class C12N 9/22 (20130101) C12N 9/93 (20130101) C12N 2810/85 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260086 — Quantum dots in modular nucleic acid scaffolds operable as nanoscale energy harvesting and focusing arrays

US 10260086	Ancona et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Mario Ancona (Alexandria, Virginia); Ellen R. Goldman (Germantown, Maryland); Susan Buckhout-White (Silver Spring, Maryland); Igor L. Medintz (Springfield, Virginia); Joseph S. Melinger (Oakton, Virginia)
ABSTRACT	The invention relates to a nanoscale antenna including a nucleic acid scaffold having a structure selected from the group consisting of a Holliday junction, a star, and a dendrimer; and a plurality of fluorophores attached to the scaffold and configured as a FRET cascade comprising at least three different types of fluorophores including at least one quantum dot, arranged with (a) a plurality of initial donor fluorophores fixed in exterior positions on the structure, (b) a terminal acceptor fluorophore fixed in a central position on the structure, and (c) a plurality of intermediate fluorophores fixed in positions on the scaffold between the initial acceptor fluorophores and the terminal acceptor fluorophores.
FILED	Friday, April 13, 2018
APPL NO	15/953152
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) Original (OR) Class C12Q 1/6818 (20130101) C12Q 2563/155 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260106 — Methods and compositions for identification of prostate cancer markers

US 10260106	Reddy et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	HENRY FORD HEALTH SYSTEM (Detroit, Michigan)
ASSIGNEE(S)	Henry Ford Health System (Detroit, Michigan)
INVENTOR(S)	G. Prem-Veer Reddy (West Bloomfield, Michigan); Mani Menon (Bloomfield, Michigan)
ABSTRACT	A method for diagnosing and treating prostate cancer in a human subject is provided, the method comprises: a. providing a sample of prostate tissue, blood, or urine from the subject; b. determining the level of expression of SEQ ID NO: 1 and the expression of SEQ ID NO: 5 in the sample, wherein an increased level of expression of SEQ ID NO:1 and a reduced level of expression of SEQ ID NO: 5 in the sample is indicative of a diagnosis that the subject has prostate cancer; and c. administering a therapeutically effective prostate cancer treatment selected from the group consisting of an androgen receptor (AR)-targeted therapy, an antimicrotubule agent, an alkylating agent and an anthracenedione to the subject to treat the prostate cancer in the human subject diagnosed with prostate cancer.
FILED	Friday, July 22, 2016
APPL NO	15/217440
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/09 (20130101) A61K 31/15 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260143 — Method and apparatus for application of metallic alloy coatings

US 10260143	Hass et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Defense University Research Instrumentation Program (DURIP)
APPLICANT(S)	Derek D. Hass (Charlottesville, Virginia); Haydn N. G. Wadley (Keswick, Virginia); Kumar P. Dharmasena (Charlottesville, Virginia); Yosef Marciano (Metar, Israel)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	Derek D. Hass (Charlottesville, Virginia); Haydn N. G. Wadley (Keswick, Virginia); Kumar P. Dharmasena (Charlottesville, Virginia); Yosef Marciano (Metar, Israel)
ABSTRACT	A directed vapor deposition (DVD) method and system for applying at least one bond coating on at least one substrate for thermal barrier coating systems. To overcome the limitations incurred by conventional methods, the DVD system uses an electron beam directed vapor deposition (DVD) technique to evaporate and deposit compositionally and morphologically controlled bond coats at high rate. The present DVD system uses the combination of an electron beam and a combined inert gas/reactive gas carrier jet of controlled composition to create engineering films. In this system, the vaporized material can be entrained in the carrier gas jet and deposited onto the substrate at a high rate and with high materials utilization efficiency. The velocity and flux of the gas atoms entering the chamber, the nozzle parameters, and the operating chamber pressure can all be significantly varied, facilitating wide processing condition variation and allowing for improved control over the properties of the deposited layer.
FILED	Friday, February 10, 2012
APPL NO	13/371044
ART UNIT	1716 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/02 (20130101) C23C 14/0021 (20130101) C23C 14/30 (20130101) C23C 14/32 (20130101) C23C 14/228 (20130101) Original (OR) Class C23C 14/243 (20130101) C23C 14/548 (20130101) C23C 16/448 (20130101) C23C 16/487 (20130101) C23C 16/45563 (20130101) C23C 28/321 (20130101) C23C 28/345 (20130101) C23C 28/3215 (20130101) C23C 28/3455 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260159 — Methods and apparatuses for mitigating tin whisker growth on tin and tin-plated surfaces by doping tin with gold

US 10260159	Woodrow, III et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S)	Thomas A. Woodrow, III (Lakeside, Texas); Jean A. Nielsen (Kent, Washington)
ABSTRACT	The present disclosure generally relates to the field of tin electroplating. More specifically, the present disclosure relates to methods for mitigating tin whisker formation on tin-plated films and tin-plated surfaces by doping the tin with gold.
FILED	Friday, July 05, 2013
APPL NO	13/935832
ART UNIT	1759 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/30 (20130101) C25D 3/48 (20130101) C25D 3/60 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10260166 — Method of growing high quality, thick SiC epitaxial films by eliminating silicon gas phase nucleation and suppressing parasitic deposition

US 10260166	Sudarshan et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	University of South Carolina (Columbia, South Carolina)
ASSIGNEE(S)	University of South Carolina (Columbia, South Carolina)
INVENTOR(S)	Tangali S. Sudarshan (Columbia, South Carolina); Tawhid Rana (Columbia, South Carolina); Haizheng Song (Columbia, South Carolina)
ABSTRACT	Methods for forming an epilayer on a surface of a substrate are generally provided. For example, a substrate can be positioned within a hot wall CVD chamber (e.g., onto a susceptor within the CVD chamber). At least two source gases can then be introduced into the hot wall CVD chamber such that, upon decomposition, fluorine atoms, carbon atoms, and silicon atoms are present within the CVD chamber. The epilayer comprising SiC can then be grown on the surface of the substrate in the presence of the fluorine atoms.
FILED	Wednesday, October 11, 2017
APPL NO	15/730321
ART UNIT	1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/14 (20130101) C30B 25/20 (20130101) C30B 25/165 (20130101) C30B 25/183 (20130101) C30B 25/186 (20130101) Original (OR) Class C30B 29/36 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02019 (20130101) H01L 21/02082 (20130101) H01L 21/02378 (20130101) H01L 21/02433 (20130101) H01L 21/02447 (20130101) H01L 21/02516 (20130101) H01L 21/02529 (20130101) H01L 21/02658 (20130101) H01L 21/30608 (20130101) H01L 29/1608 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260171 — Methods for making carbon fibers for high temperature applications

US 10260171	Kaukler
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	William Felix Kaukler (Huntsville, Alabama)
ASSIGNEE(S)	The Board of Trustees of the University of Alabama, For and on behalf of The University of Alabama in Huntsville (Huntsville, Alabama)
INVENTOR(S)	William Felix Kaukler (Huntsville, Alabama)
ABSTRACT	The present invention relates to a method for the continuous production of low thermal conductivity endless filament yarns with a compact, homogeneous structural morphology. The presently disclosed methods utilize safe and recyclable ionic liquids to produce carbon fiber precursors from cellulose. The fibers are produced by the carbonization of cellulose carbon fiber precursors. The precursor fiber filaments have an increased tear resistance with simultaneously sufficient elongation, a round or crenulated cross-section, and homogeneous fiber morphology. The filament yarns exhibit performance characteristics similar to those produced from traditional viscose rayon. The resulting fibers are especially suited for aerospace applications in composite materials used at the limits of high temperatures, for instance in structures found in rocket nozzles or atmospheric reentry heat shields on spacecraft.
FILED	Tuesday, January 17, 2017
APPL NO	15/408183
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 37/006 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 1/02 (20130101) D01D 1/103 (20130101) D01D 5/06 (20130101) D01D 10/06 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/16 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2505/12 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260419 — Cooling system

US 10260419	Cerny et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Matthew Robert Cerny (West Chester, Ohio); Christopher James Kroger (Cincinnati, Ohio); Brandon Wayne Miller (Cincinnati, Ohio)
ABSTRACT	A thermal management system for a gas turbine engine and/or an aircraft is provided including a thermal transport bus having a heat exchange fluid flowing therethrough. The thermal management system also includes a plurality of heat source exchangers and at least one heat sink exchanger. The plurality of heat source exchangers and the at least one heat sink exchanger are in thermal communication with the heat exchange fluid in the thermal transport bus. The plurality of heat source exchangers are arranged along the thermal transport bus and configured to transfer heat from one or more accessory systems to the heat exchange fluid, and the at least one heat sink exchanger is located downstream of the plurality of heat source exchangers and configured to remove heat from the heat exchange fluid.
FILED	Friday, July 31, 2015
APPL NO	14/814546
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/06 (20130101) Original (OR) Class F02C 7/14 (20130101) F02C 7/16 (20130101) F02C 7/185 (20130101) F02C 7/224 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/213 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 1/00 (20130101) F25B 41/062 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/00 (20130101) F28D 2021/0021 (20130101) F28D 2021/0026 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 27/02 (20130101) F28F 2250/08 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260533 — Pneumatic insect robots

US 10260533	Shevchenko et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Yanina Shevchenko (Cambridge, Massachusetts); George M. Whitesides (Newton, Massachusetts); Adam Stokes (Watertown, Massachusetts); Gabrielle Compton (Welling, Oklahoma); Alex Nemiroski (Cambridge, Massachusetts)
ABSTRACT	A modular pneumatic robotic actuator, including a first elongated hollow structure and a second elongated hollow structure connected to each other at a moveable joint; an inflatable bladder comprised of an elastomeric material disposed at the said joint and immobilized between the first and second hollow structures, wherein the said inflatable bladder inflates preferentially away from the joint; and a restraining membrane comprised of an elastomeric material disposed over the bladder and connecting the first and second hollow structures, wherein the said restraining membrane is relaxed when the bladder is deflated.
FILED	Tuesday, August 01, 2017
APPL NO	15/665583
ART UNIT	3618 — Electrical Circuits and Systems
CURRENT CPC	Motor Vehicles; Trailers B62D 57/032 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/103 (20130101) Original (OR) Class F15B 2215/305 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260849 — Off-on explosive warhead for high energy formulations with tailorable output performance

US 10260849	Piehler et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY U.S. ARMY RESEARCH LABORATORY (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Thuvan Piehler (Fallston, Maryland); Rohan Joel Banton (Bel Air, Maryland)
ABSTRACT	A warhead includes a casing having a removable front portion, a plurality of explosive segments positioned in the casing, a plurality of spacers positioned in the casing and separating the plurality of explosive segments from each other, and a removable piston configured to be inserted inside the removable front portion of the casing, wherein the removable piston pushes against the plurality of explosive segments to create a continuous segment. The removable piston may push against the plurality of explosive segments to close the plurality of spacers and move the warhead from an off position to an on position. The continuous segment may be above an explosive failure thickness in the on position. The continuous segment may be configured to detonate upon reaching the failure thickness.
FILED	Tuesday, March 21, 2017
APPL NO	15/464747
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/208 (20130101) Original (OR) Class Ammunition Fuzes; Arming or Safety Means Therefor F42C 15/184 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260858 — Spatial modulation of light to determine object length

US 10260858	Martini et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S)	Joerg Martini (San Francisco, California); Marshall W. Bern (San Carlos, California); Noble M. Johnson (Menlo Park, California); Peter Kiesel (Palo Alto, California); Doron Kletter (San Mateo, California); Bowen Cheng (Atherton, California); Michael I. Recht (San Carlos, California)
ABSTRACT	Spatially modulated light emanating from an object moving along a flow path is used to determine various object characteristics including object length along the flow direction. Light emanating from at least one object moving along in a flow path along a flow direction of a spatial filter is sensed. The intensity of the sensed light is time modulated according to features of the spatial filter. A time varying electrical signal is generated which includes a plurality of pulses in response to the sensed light. Pulse widths of at least some of the pulses are measured at a fraction of a local extremum of the pulses. The length of the object along the flow direction is determined based on the measured pulse widths.
FILED	Monday, April 23, 2018
APPL NO	15/960079
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/043 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 2015/1447 (20130101) G01N 2015/1493 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/36 (20130101) G01P 15/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260866 — Methods and apparatus for enhancing depth maps with polarization cues

US 10260866	Kadambi et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Achuta Kadambi (Cambridge, Massachusetts); Vage Taamazyan (Chelyabinsk, Russian Federation); Boxin Shi (Singapore, Singapore); Ramesh Raskar (Cambridge, Massachusetts)
ABSTRACT	A 3D imaging system uses a depth sensor to produce a coarse depth map, and then uses the coarse depth map as a constraint in order to correct ambiguous surface normals computed from polarization cues. The imaging system outputs an enhanced depth map that has a greater depth resolution than the coarse depth map. The enhanced depth map is also much more accurate than could be obtained from the depth sensor alone. In many cases, the imaging system extracts the polarization cues from three polarized images. Thus, in many implementations, the system takes only three extra images—in addition to data used to generate the coarse depth map—in order to dramatically enhance the coarse depth map.
FILED	Sunday, December 27, 2015
APPL NO	14/979433
ART UNIT	2482 — Recording and Compression
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/24 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/507 (20170101) G06T 7/514 (20170101) G06T 2207/10028 (20130101) G06T 2207/10141 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260953 — Applique and method for thermographic inspection

US 10260953	Engelbart et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	THE BOEING COMPANY (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Roger W. Engelbart (St. Louis, Missouri); Nathan R. Smith (St. Charles, Missouri); Loyal B. Shawgo (O'Fallon, Missouri)
ABSTRACT	A method of thermographic inspection includes absorbing, at an applique applied to a test area of an article, light from a testing light source. The method further includes emitting, by the applique, thermal radiation directed to a capture device, the thermal radiation corresponding to at least a portion of the light absorbed by the applique.
FILED	Thursday, August 11, 2016
APPL NO	15/235024
ART UNIT	2884 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/0066 (20130101) Original (OR) Class G01J 5/0887 (20130101) G01J 5/0896 (20130101) G01J 2005/0077 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/8806 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261022 — Self-indicating zirconium hydroxide and other porous metal hydroxides incorporating additional metals, metal oxides, and/or metal salts for toxic chemical removal and sensing

US 10261022	Peterson et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Chemical Biological Center (CCDC CBC) Research, Development and Engineering Command (RDECOM) Edgewood Chemical Biological Center (ECBC)
APPLICANT(S)	U.S. Army Edgewood Chemical Biological Center (, None)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Gregory W Peterson (Belcamp, Maryland); Joseph A Rossin (Columbus, Ohio); Jennifer R Soliz (Baltimore, Maryland); Kathryn L. Killops (Abingdon, Maryland)
ABSTRACT	Processes for sensing a variety of toxic chemicals and/or processes for determining the residual life of a filter or filtration system are provided. Exemplary process for sensing a toxic chemical include contacting a toxic chemical, or byproduct thereof, with a sorbent that includes a porous metal hydroxide and a transition metal reactant suitable to react with a toxic chemical or byproduct thereof. The sorbent is contacted with the toxic chemical or byproduct thereof for a sampling time. A difference between a post-exposure colorimetric state of the sorbent and a pre-exposure colorimetric state of the sorbent or control is determined to thereby sense exposure to, or the presence of, the toxic chemical or byproduct thereof.
FILED	Thursday, April 26, 2018
APPL NO	15/963524
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/29 (20130101) G01N 21/78 (20130101) G01N 21/783 (20130101) Original (OR) Class G01N 31/22 (20130101) G01N 33/0036 (20130101) G01N 33/0037 (20130101) G01N 33/0042 (20130101) G01N 33/0044 (20130101) G01N 33/0049 (20130101) G01N 33/0052 (20130101) G01N 33/0054 (20130101) G01N 33/0057 (20130101) G01N 33/2025 (20190101) Technical Subjects Covered by Former US Classification Y10T 436/184 (20150115) Y10T 436/186 (20150115) Y10T 436/255 (20150115) Y10T 436/175383 (20150115) Y10T 436/178459 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

10261071 — Volatile organic compounds as diagnostic breath markers for pulmonary oxygen toxicity

US 10261071	Hall et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Richard T. Mahon (Germantown, Maryland); Aaron A Hall (Clarksburg, Maryland); William A Cronin (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Aaron A. Hall (Clarksburg, Maryland); Richard T. Mahon (Germantown, Maryland); William A. Cronin (Bethesda, Maryland)
ABSTRACT	A set of volatile organic compounds is provided, comprising Benzene, 2,3,4-trimethyl-Pentane, 1,4-dimethyl-, trans-Cyclohexane, 2,2,4-trimethyl-Hexane, 1,7,7-trimethyl-Tricyclo[2.2.1.0(2,6)]heptane, and 4-ethyl-3-Octene for breath analysis. Methods of identifying these VOCs and use thereof in diagnosing, monitoring the onset of pulmonary toxicity are also disclosed.
FILED	Sunday, July 09, 2017
APPL NO	15/644793
ART UNIT	2881 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/72 (20130101) G01N 30/7206 (20130101) G01N 33/497 (20130101) Original (OR) Class G01N 2030/884 (20130101) G01N 2033/4975 (20130101) G01N 2560/00 (20130101) G01N 2800/12 (20130101) G01N 2800/50 (20130101) Electric Digital Data Processing G06F 19/707 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261089 — Methods and arrays for target analyte detection and determination of target analyte concentration in solution

US 10261089	Walt et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S)	Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S)	David R. Walt (Boston, Massachusetts); David M. Rissin (Somerville, Massachusetts)
ABSTRACT	Arrays of single molecules and methods of producing an array of single molecules are described. Arrays with defined volumes between 10 attoliters and 50 picoliters enable single molecule detection and quantitation.
FILED	Friday, July 08, 2016
APPL NO	15/205497
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 2527/143 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/543 (20130101) G01N 33/581 (20130101) Original (OR) Class G01N 33/54346 (20130101) G01N 33/54366 (20130101) G01N 33/54386 (20130101) G01N 2333/938 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261139 — Method of making a magnetic field sensor

US 10261139	van 't Erve et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Olaf M. J. van 't Erve (Falls Church, Virginia); Enrique Cobas (Capitol Heights, Maryland); Shu-Fan Cheng (Silver Spring, Maryland); Berend T. Jonker (Waldorf, Maryland)
ABSTRACT	A method of making a magnetic field sensor using in situ solid source graphene and graphene induced anti-ferromagnetic coupling and spin filtering, comprising providing a substrate comprising silicon wafers and thermal oxide, performing DC magnetron sputtering, back-sputtering the substrate, growing amorphous carbon on the substrate, sputtering and growing a first ferromagnetic metal surface on the amorphous carbon, annealing the substrate and the amorphous carbon and the first ferromagnetic metal surface, forming a graphene film on the first ferromagnetic metal surface, wherein the first ferromagnetic metal surface comprises NiFe, sputtering and growing a second ferromagnetic film on the graphene film, and capping the second ferromagnetic film with a platinum layer.
FILED	Monday, February 06, 2017
APPL NO	15/425731
ART UNIT	3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0052 (20130101) G01R 33/093 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10261155 — Systems and methods for acceleration magnetic resonance fingerprinting

US 10261155	Cohen
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Ouri Cohen (Brookline, Massachusetts)
ABSTRACT	Systems and methods for accelerating magnetic resonance fingerprinting (“MRF”} acquisitions are described. Acquisition parameters can be optimized to reduce the number of acquisitions necessary while maximizing the discrimination between the physical parameters to be estimated. The systems and methods may also include implementing pulse sequences that rapidly acquire large volumes of k-space data, including echo-planar imaging (“EPI”} and segmented EPI sequences.
FILED	Thursday, January 29, 2015
APPL NO	15/117337
ART UNIT	2867 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/482 (20130101) G01R 33/543 (20130101) G01R 33/5616 (20130101) Original (OR) Class G01R 33/5618 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261163 — Low frequency sound sensor array for positioning and methods of using same

US 10261163	McIntire
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	John P. McIntire (Dayton, Ohio)
ABSTRACT	A system and method of using the system are provided. The system can include at least one source, a plurality of sensors, and a processing device. The source can emit one or more low frequency sounds. The sensors can sense the low frequency sounds and transform the low frequency sounds into one or more signals including a plurality of data values. The processing device can be communicatively operable with the sensors to receive the signals and determine positioning information of the sensors based on the data values.
FILED	Thursday, April 13, 2017
APPL NO	15/486550
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/808 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10261296 — Telecentric reflective imager

US 10261296	Mitchell
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Thomas A. Mitchell (Nazareth, Pennsylvania)
ASSIGNEE(S)	WAVEFRONT RESEARCH, INC. (Northampton, Pennsylvania)
INVENTOR(S)	Thomas A. Mitchell (Nazareth, Pennsylvania)
ABSTRACT	A reflective imager design that is telecentric in image space, or equivalently telecentric at an image plane, or equivalently having an exit pupil located substantially at infinity, while also having an external entrance pupil and a high throughput or fast optical speed is described.
FILED	Friday, August 28, 2015
APPL NO	14/839302
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 13/22 (20130101) G02B 17/0647 (20130101) Original (OR) Class G02B 27/0025 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261297 — Method and apparatus for remote imaging

US 10261297	Cappiello
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Gregory G. Cappiello (Windham, New Hampshire)
ABSTRACT	A remote imaging apparatus, and corresponding method, includes a hyperbolic primary mirror that receives light from a remote object to be imaged. The primary mirror has a continuous surface that reflects, at least twice, the light from the remote object. The apparatus also includes a hyperbolic secondary mirror having a continuous surface that reflects, at least twice, the light from the remote object. The secondary mirror delivers the light to a field corrector via a port of the hyperbolic primary mirror, and the field corrector is configured to correct for an optical aberration of one or both of the hyperbolic primary and secondary mirrors. Embodiments can provide low distortion, small aspect ratios, and small form factors and moments of inertia for fleets satellite-based and other imaging systems.
FILED	Tuesday, June 27, 2017
APPL NO	15/634428
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 7/182 (20130101) G02B 17/0808 (20130101) G02B 17/0852 (20130101) Original (OR) Class G02B 23/02 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261388 — Chip-scale two-dimensional optical phased array with simplified controls

US 10261388	Pruessner et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Marcel W. Pruessner (Chevy Chase, Maryland); William S. Rabinovich (Silver Spring, Maryland); Rita Mahon (Silver Spring, Maryland); Peter G. Goetz (Springfield, Virginia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Marcel W. Pruessner (Chevy Chase, Maryland); William S. Rabinovich (Silver Spring, Maryland); Rita Mahon (Silver Spring, Maryland); Peter G. Goetz (Springfield, Virginia)
ABSTRACT	A device includes a waveguide grating out-coupler, and a tunable uniform phase shifter communicating with the waveguide grating out-coupler. The tunable uniform phase shifter steers a Hat phase front along a first angle in a first plane. Optionally, the waveguide grating out-coupler includes a modulated refractive index and a physical grating period. The tunable uniform phase shifter controls the refractive index, thereby controlling an effective grating period. The grating period relates to die modulated refractive index, and the physical grating period. Optionally, the tunable uniform phase shifter includes a first thermo-optic phase shifter, a first electro-optic phase shifter, or a first micro-electro-mechanical system index perturbation phase shifter. Optionally, the tunable linear gradient phase shifter communicates with the waveguide grating out-coupler and steers a beam along the flat phase front along a second angle in a second plane, which is perpendicular to the first plane.
FILED	Tuesday, February 27, 2018
APPL NO	15/906204
ART UNIT	2883 — Optics
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4813 (20130101) G01S 7/4817 (20130101) Optical Elements, Systems, or Apparatus G02B 6/124 (20130101) G02B 6/2804 (20130101) G02B 6/2813 (20130101) G02B 6/2821 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/292 (20130101) Original (OR) Class G02F 2201/06 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261389 — Methods and systems for optical beam steering

US 10261389	Skirlo et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Scott Skirlo (Boston, Massachusetts); Cheryl Marie Sorace-Agaskar (Bedford, Massachusetts); Marin Soljacic (Belmont, Massachusetts); Simon Verghese (Arlington, North Carolina); Jeffrey S. Herd (Rowley, Massachusetts); Paul William Juodawlkis (Arlington, Massachusetts); Yi Yang (Cambridge, Massachusetts); Dirk Robert Englund (Cambridge, Massachusetts); Mihika Prabhu (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Scott Skirlo (Boston, Massachusetts); Cheryl Marie Sorace-Agaskar (Bedford, Massachusetts); Marin Soljacic (Belmont, Massachusetts); Simon Verghese (Arlington, North Carolina); Jeffrey S. Herd (Rowley, Massachusetts); Paul William Juodawlkis (Arlington, Massachusetts); Yi Yang (Cambridge, Massachusetts); Dirk Robert Englund (Cambridge, Massachusetts); Mihika Prabhu (Cambridge, Massachusetts)
ABSTRACT	An integrated optical beam steering device includes a planar dielectric lens that collimates beams from different inputs in different directions within the lens plane. It also includes an output coupler, such as a grating or photonic crystal, that guides the collimated beams in different directions out of the lens plane. A switch matrix controls which input port is illuminated and hence the in-plane propagation direction of the collimated beam. And a tunable light source changes the wavelength to control the angle at which the collimated beam leaves the plane of the substrate. The device is very efficient, in part because the input port (and thus in-plane propagation direction) can be changed by actuating only log₂N of the N switches in the switch matrix. It can also be much simpler, smaller, and cheaper because it needs fewer control lines than a conventional optical phased array with the same resolution.
FILED	Thursday, June 22, 2017
APPL NO	15/630235
ART UNIT	2883 — Optics
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/2955 (20130101) G02F 1/3136 (20130101) Original (OR) Class G02F 2001/311 (20130101) G02F 2201/02 (20130101) G02F 2201/06 (20130101) G02F 2201/302 (20130101) G02F 2203/70 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261911 — Apparatus and method for computational workflow management

US 10261911	Ahr et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Sea Systems Command (NAVSEA) Johns Hopkins University Applied Physics Laboratory (JH APL)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Brian E. Ahr (Ellicott City, Maryland); Jonathan Z. Gehman (Silver Spring, Maryland); Khadir A. Griffith (Towson, Maryland); Gary L. Jackson, II (Laurel, Maryland); William J. La Cholter (Washington, District of Columbia); Anthony J. Castellani (Columbia, Maryland)
ABSTRACT	Apparatuses and methods for performing computational workflow management are provided. An example apparatus may include processing circuitry. The processing circuitry may be configured to receive a computation resource reservation request for cache from a client to perform a computation, and decompose the computation into a workflow of tasks, generate a task label for each task result and the associated task, and compare a selected task label with previous task labels to determine if the selected task label matches one of the previous task labels. The processing circuitry may be further configured to, in response to determining that the selected task label matches one of the previous task labels, perform the computation using a task result that is associated with the matched one of the previous task labels that is currently stored in the cache for the task result of the selected task label.
FILED	Thursday, July 06, 2017
APPL NO	15/642364
ART UNIT	2193 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/5016 (20130101) G06F 9/5066 (20130101) G06F 12/121 (20130101) G06F 12/0842 (20130101) G06F 12/0891 (20130101) Original (OR) Class G06F 2209/5014 (20130101) G06F 2209/5017 (20130101) G06F 2212/60 (20130101) G06F 2212/1041 (20130101) G06F 2212/1052 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261920 — Static image RAM drive

US 10261920	Bell
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Donna Bell (Jacksonville, Florida)
ASSIGNEE(S)	The United States of America as presented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jason Bell (Jacksonville, Florida)
ABSTRACT	An apparatus and method of a static image RAM drive is provided. The system includes a field programmable gate array (FPGA), a volatile memory drive, a non-volatile memory drive, and a power source. The non-volatile memory drive has a secure memory space. The secure memory space is programmed with an encryption key and an encrypted disk image. In response to a power cycle, the FPGA reads the encrypted disk image from the non-volatile memory, authenticates the disk image using the encryption key, decrypts the encrypted disk image, and writes the decrypted disk image to the volatile memory. The decrypted disk image is used to boot a computer. The computer is booted to a known good state each time the power is cycled.
FILED	Thursday, September 07, 2017
APPL NO	15/697565
ART UNIT	2186 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 9/4401 (20130101) G06F 12/1408 (20130101) Original (OR) Class G06F 21/76 (20130101) G06F 21/79 (20130101) G06F 21/80 (20130101) G06F 21/575 (20130101) G06F 2212/1052 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0891 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261994 — Method and system for automatic management of reputation of translators

US 10261994	Marcu et al.
FUNDED BY	Department of Defense (DOD) Assistant Secretary of Defense for Special Operations/Low-Intensity Conflict (ASD SOLIC) Technical Support Working Group (TSWG) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Daniel Marcu (Manhattan Beach, California); Markus Dreyer (Santa Monica, California)
ASSIGNEE(S)	SDL Inc. (Wakefield, Massachusetts)
INVENTOR(S)	Daniel Marcu (Manhattan Beach, California); Markus Dreyer (Santa Monica, California)
ABSTRACT	The present invention provides a method that includes receiving a result word set in a target language representing a translation of a test word set in a source language. When the result word set is not in a set of acceptable translations, the method includes measuring a minimum number of edits to transform the result word set into a transform word set. The transform word set is in the set of acceptable translations. A system is provided that includes a receiver to receive a result word set and a counter to measure a minimum number of edits to transform the result word set into a transform word set. A method is provided that includes automatically determining a translation ability of a human translator based on a test result. The method also includes adjusting the translation ability of the human translator based on historical data of translations performed by the human translator.
FILED	Friday, May 25, 2012
APPL NO	13/481561
ART UNIT	2659 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC	Electric Digital Data Processing G06F 17/2854 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0639 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10262090 — System and method for assessing the remaining useful life of an insulation system

US 10262090	Nyanteh et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S)	Yaw D. Nyanteh (Tallahassee, Florida); Lukas Graber (Tallahassee, Florida); Horatio Rodrigo (Billerica, Massachusetts); Sanjeev K. Srivastava (Princeton, New Jersey); Chris S. Edrington (Tallahassee, Florida); David S. Cartes (Tallahassee, Florida)
ABSTRACT	A system and method for electrical tree simulation based on a modification of a discharge avalanche model with an application of a charge simulation method to determine partial discharge data during the growth of electrical trees in an insulation system and a method of using the model to determine the remaining useful life of an insulation system.
FILED	Wednesday, November 12, 2014
APPL NO	14/539580
ART UNIT	2194 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 17/5036 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10262143 — System and method for modeling and analyzing the impact of cyber-security events on cyber-physical systems

US 10262143	Thomas et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The MITRE Corporation (McLean, Virginia)
ASSIGNEE(S)	The MITRE Corporation (McLean, Virginia)
INVENTOR(S)	Roshan K. Thomas (Fairfax Station, Virginia); Mary C. Hatfield (Centreville, Virginia); Ivan Lozano (Arlington, Virginia); Edward Overly (Oak Hill, Virginia); Joel G. Korb (Reston, Virginia); Jimmy Vu (Fairfax, Virginia)
ABSTRACT	A system and method for systematically undertaking model-based security analysis of a cyber physical system (CPS) is provided. In one example, a cyber model simulation and a control system simulation are mapped using various methods to determine which portions of the cyber-model simulation and the control system simulation are correlated with one another. Using the determined correlation, when a cyber-attack is generated on the cyber model simulation, a corresponding attack hook can be generated for the control system model. The attack hook is configured to be integrated into the control system model so as to mimic the effect on the control system that a cyber-attack can engender. Once one or more attack hooks are generated, the user can place the hooks into the control system simulation schemas and run a series of simulations to determine the effects of a cyber event on the control system in a CPS.
FILED	Tuesday, September 13, 2016
APPL NO	15/264028
ART UNIT	2498 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 17/5009 (20130101) G06F 21/577 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10262224 — Optical flow estimation using a neural network and egomotion optimization

US 10262224	Harguess et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Joshua D. Harguess (San Diego, California); Christopher M. Barngrover (San Diego, California); Amin M. Rahimi (San Diego, California)
ABSTRACT	A camera is connected to a trained neural network. The camera takes an image of a scene and transmits the image to the neural network. A processor connected to the neural network has a localization filter and a robot model implemented therein. A global positioning system (GPS) receiver and inertial measurement unit (IMU) transmit GPS information and IMU information, respectively, to the processor. The localization filter filters the received GPS and IMU information and inputs the filtered information into the robot model. The robot model outputs current position information corresponding to the current image and previous position information corresponding to the respective one or more previous images. The neural network uses the current image and associated current position information and the one or more previous images and respective associated previous position information to generate an estimated optical flow image, which is transmitted to an object detection system.
FILED	Wednesday, July 19, 2017
APPL NO	15/654573
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00624 (20130101) G06K 9/3233 (20130101) G06K 9/3241 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 2207/10021 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 13/19608 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10262229 — Wide-area salient object detection architecture for low power hardware platforms

US 10262229	Rao et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Shankar R. Rao (Agoura Hills, California); Narayan Srinivasa (Portland, Oregon)
ABSTRACT	Described is a system for detecting multiple salient objects in an image using low power hardware. From consecutive pair of image frames of a set of input image frames, image channels are generated. The image channels are resized into multiple image scales that specify a relative size of a salient object in the image frames. A patch-based spectral transform is applied to overlapping image patches in the resized image channel, generating salient patches. Saliency patches are combined into a saliency map for each resized image channel, resulting in multiple saliency maps. The saliency maps are combined into an aggregate saliency map. An adaptive threshold is applied to the aggregate saliency map to determine which pixels in the aggregate saliency map correspond to a detected salient object region including a salient object. An object bounding box is generated for each salient object and output to a display.
FILED	Wednesday, September 21, 2016
APPL NO	15/272247
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4676 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 3/40 (20130101) G06T 7/11 (20170101) G06T 7/0081 (20130101) G06T 2207/10004 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10262428 — System and method for adaptive range 3D scanning

US 10262428	Rosman et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) National Nuclear Security Administration (NNSA)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Guy Rosman (Newton, Massachusetts); Daniela Rus (Weston, Massachusetts); John W. Fisher, III (Chestnut Hill, Massachusetts)
ABSTRACT	A scanner system is configured for acquiring three dimensional image information of an object. The scanner includes a projector, a camera, a graphics processing device, and a processor. The projector projects one of several pre-defined patterns upon the object. The camera captures an image from the object, which is received by the processor. The processor approximates mutual information from the object and the pattern using the graphics processing device, and selects a second pattern for projecting on the object.
FILED	Friday, April 07, 2017
APPL NO	15/482375
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/2518 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/2036 (20130101) G06K 2209/40 (20130101) Image Data Processing or Generation, in General G06T 7/521 (20170101) Original (OR) Class G06T 17/05 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10262714 — Low power sense amplifier based on phase transition material

US 10262714	Gupta et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Sumeet Kumar Gupta (State College, Pennsylvania); Ahmedullah Aziz (State College, Pennsylvania); Nikhil Shukla (South Bend, Indiana); Suman Datta (South Bend, Indiana); Xueqing Li (State College, Pennsylvania); Vijaykrishnan Narayanan (University Park, Pennsylvania)
ABSTRACT	A sense amplifier utilizes a phase transition material (PTM) in conjunction with CMOS circuits to provide a precise sensing threshold. The sense amplifier can be used in memory applications to sense states of stored bits with high accuracy and robustness. In one sense amplifier, a first diode-connected transistor has gate and drain nodes coupled to an input node of the sense amplifier, a second transistor has a gate node coupled to the gate node of the first diode-connected transistor, and the PTM is coupled to the source node of the second transistor. In another sense amplifier, a first transistor has a gate node coupled to an input node of the sense amplifier, a PTM is coupled to the source node of the first transistor, and an output stage including an inverter is coupled between a drain node of the first transistor and an output node of the sense amplifier.
FILED	Monday, June 05, 2017
APPL NO	15/614261
ART UNIT	2825 — Semiconductors/Memory
CURRENT CPC	Static Stores G11C 7/062 (20130101) G11C 11/1673 (20130101) Original (OR) Class G11C 13/0002 (20130101) G11C 13/004 (20130101) G11C 13/0007 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10262856 — Selective oxidation of transition metal nitride layers within compound semiconductor device structures

US 10262856	Meyer et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United State of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	David J. Meyer (Fairfax, Virginia); Brian P. Downey (Alexandria, Virginia); Daniel S. Green (McLean, Virginia)
ABSTRACT	Methods for integrating transition metal oxide (TMO) layers into a compound semiconductor device structure via selective oxidation of transition metal nitride (TMN) layers within the structure.
FILED	Friday, December 15, 2017
APPL NO	15/843041
ART UNIT	2813 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0223 (20130101) H01L 21/0254 (20130101) H01L 21/02378 (20130101) H01L 21/02447 (20130101) H01L 21/02458 (20130101) Original (OR) Class H01L 21/02491 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10262871 — Formation of field-tunable silicon carbide defect qubits with optically transparent electrodes and silicon oxide surface passivation

US 10262871	Nayfeh et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Osama Nayfeh (San Diego, California); Anna Leese De Escobar (San Diego, California); Brad Liu (San Diego, California); Patrick Sims (San Diego, California); Sam Carter (Waldorf, Maryland); David Kurt Gaskill (Alexandria, Virginia); Tom Reinecke (Alexandria, Virginia)
ABSTRACT	A method includes depositing a layer of silicon oxide onto a layer of silicon carbide; ion implanting the layer of silicon carbide, annealing the ion implanted layer of silicon carbide to produce defects within the layer of silicon carbide, performing photolithography using a mask layer on regions of the layer of silicon carbide to define regions for electrode deposition, removing the layer of silicon oxide from the layer of silicon carbide in the one or more regions for electrode deposition, forming one or more electrodes by depositing indium tin oxide (ITO) in each of the regions for electrode deposition, performing a first lift-off operation to remove the mask layer surrounding the electrodes, depositing a passivation and gate silicon oxide layer on top of the layer of silicon carbide and the electrodes, and performing a second lift-off operation to fabricate an optically transparent ITO gate between the electrodes.
FILED	Wednesday, January 31, 2018
APPL NO	15/884680
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/325 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/105 (20130101) C30B 29/36 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0054 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/049 (20130101) H01L 21/0276 (20130101) H01L 21/02447 (20130101) H01L 21/02529 (20130101) H01L 21/31144 (20130101) Original (OR) Class H01L 21/76826 (20130101) H01L 23/5329 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10262954 — Transient electronic device with ion-exchanged glass treated interposer

US 10262954	Limb et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S)	Scott J. H. Limb (Palo Alto, California); Gregory L. Whiting (Menlo Park, California)
ABSTRACT	A transient electronic device utilizes a glass-based interposer that is treated using ion-exchange processing to increase its fragility, and includes a trigger device operably mounted on a surface thereof. An integrated circuit (IC) die is then bonded to the interposer, and the interposer is mounted to a package structure where it serves, under normal operating conditions, to operably connect the IC die to the package I/O pins/balls. During a transient event (e.g., when unauthorized tampering is detected), a trigger signal is transmitted to the trigger device, causing the trigger device to generate an initial fracture force that is applied onto the glass-based interposer substrate. The interposer is configured such that the initial fracture force propagates through the glass-based interposer substrate with sufficient energy to both entirely powderize the interposer, and to transfer to the IC die, whereby the IC die also powderizes (i.e., visually disappears).
FILED	Tuesday, August 29, 2017
APPL NO	15/689566
ART UNIT	2812 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/486 (20130101) H01L 21/4853 (20130101) H01L 21/4864 (20130101) H01L 23/15 (20130101) H01L 23/57 (20130101) H01L 23/573 (20130101) Original (OR) Class H01L 23/576 (20130101) H01L 23/49827 (20130101) H01L 23/49838 (20130101) H01L 23/49894 (20130101) H01L 24/00 (20130101) H01L 24/16 (20130101) H01L 25/0655 (20130101) H01L 2224/16157 (20130101) H01L 2224/16235 (20130101) H01L 2924/15311 (20130101) Pulse Technique H03K 19/17768 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263170 — Bumped resonator structure

US 10263170	Brink et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Markus Brink (White Plains, New York); Antonio D. Corcoles-Gonzalez (Mount Kisco, New York); Jay M. Gambetta (Yorktown Heights, New York); Sami Rosenblatt (White Plains, New York); Firat Solgun (Ossining, New York)
ABSTRACT	A technique relates a structure. An inductive element is on a first surface. A capacitive element is on the first surface and a second surface. An interconnect structure is between the first surface and the second surface.
FILED	Thursday, November 30, 2017
APPL NO	15/827729
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) H01L 39/025 (20130101) Original (OR) Class H01L 39/223 (20130101) H01L 39/2493 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263173 — Multi-axis piezoelectric transducer

US 10263173	Najafi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Materiel Command (AMC)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Khalil Najafi (Ann Arbor, Michigan); Ethem Aktakka (Ann Arbor, Michigan)
ABSTRACT	A multi-axis transducer is provided. The transducer includes: a stationary member; at least two connecting members and two or more energy-conversion elements disposed on each connecting member. Each connecting member is attached at one location thereof to one of the stationary member or a second connecting member and, in response to a stimuli, is free to move along any of three geometric axes that are perpendicular to each other. Each energy-conversion element operates to convert motion of the connecting member to electrical energy or vice versa. A common geometric plane passes through each of the at least two connecting members and the stationary member, and the two largest dimensions of each connecting member defines a geometric plane that is parallel with the common geometric plane.
FILED	Saturday, January 16, 2016
APPL NO	14/997496
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/0825 (20130101) Original (OR) Class H01L 41/0946 (20130101) H01L 41/0953 (20130101) H01L 41/1136 (20130101) Electric Machines Not Otherwise Provided for H02N 2/0095 (20130101) H02N 2/188 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263186 — Bulk heterojunction organic photovoltaic cells made by glancing angle deposition

US 10263186	Forrest et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Stephen R. Forrest (Ann Arbor, Michigan); Ning Li (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Stephen R. Forrest (Ann Arbor, Michigan); Ning Li (Ann Arbor, Michigan)
ABSTRACT	A method of making a bulk heterojunction organic photovoltaic cell by glancing angle deposition. As the disclosed method relies on a trajectory of incident vapor flux that is not parallel to the substrate normal, micro and nano-scale columnar structures of thin films can be grown on the substrate. There is also disclosed a method of forming a donor-acceptor heterojunction by depositing at least one additional organic material over the columnar structures.
FILED	Tuesday, July 27, 2010
APPL NO	12/843949
ART UNIT	2817 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0008 (20130101) H01L 51/0012 (20130101) Original (OR) Class H01L 51/0046 (20130101) H01L 51/424 (20130101) H01L 51/4253 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263337 — Method for multiple-input multiple-output communication using single port radiation pattern reconfigurable antennas

US 10263337	Daly
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Michael P. Daly (San Diego, California)
ABSTRACT	An aspect of the present invention is drawn to a communication system that includes an electrically steerable parasitic array transmitter antenna, a transmitter driver, an electrically steerable parasitic array receiver antenna, and a receiver driver. The transmitter driver is arranged such that it is operable to enable the electrically steerable parasitic array transmitter antenna to transmit a beam having a first directional vector at a first time, a second directional vector at a second time, and an n^thdirectional vector at an n^thtime. The receiver driver is arranged such that it is operable to enable the electrically steerable parasitic array receiver antenna to receive a beam having a third directional vector at a third time, a fourth directional vector at a fourth time, and an m^thdirectional vector at an m^thtime.
FILED	Thursday, December 07, 2017
APPL NO	15/834408
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 3/2629 (20130101) H01Q 5/385 (20150115) Original (OR) Class H01Q 25/002 (20130101) Transmission H04B 7/0413 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263393 — Vertical-cavity surface-emitting device with epitaxial index guide

US 10263393	Deppe
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida); sdPhotonics, LLC (Oviedo, Florida)
ASSIGNEE(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S)	Dennis G. Deppe (Oviedo, Florida)
ABSTRACT	A semiconductor vertical resonant cavity light source includes an upper and lower mirror that define a vertical resonant cavity. An active region is within the cavity for light generation between the upper and lower mirror. At least one cavity spacer region is between the active region and the upper mirror or lower mirror. The cavity includes an inner mode confinement region and an outer current blocking region. An index guide in the inner mode confinement region is between the cavity spacer region and the upper or lower mirror. The index guide and outer current blocking region each include a lower and upper epitaxial material layer thereon with an epitaxial interface region in between. At least a top surface of the lower material layer includes aluminum in the interface region throughout a full area of an active part of the vertical light source.
FILED	Thursday, February 15, 2018
APPL NO	15/897672
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/183 (20130101) H01S 5/187 (20130101) H01S 5/1833 (20130101) H01S 5/2018 (20130101) H01S 5/2059 (20130101) H01S 5/2072 (20130101) H01S 5/18308 (20130101) H01S 5/18327 (20130101) H01S 5/18333 (20130101) Original (OR) Class H01S 5/18358 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263541 — Robust single-phase DC/AC inverter for highly varying DC voltages

US 10263541	Sanfelice et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Electrical and Communications Systems (ECS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Ricardo G. Sanfelice (Santa Cruz, California); Jun Chai (Santa Cruz, California)
ABSTRACT	A single-phase DC/AC inverter has a single-phase inverter bridge with binary switches connected to an RLC low-pass filter. Digital control logic in a control circuit (or in a microcontroller) determines and controls a logic state q determining the position of the switches in the inverter bridge from sensed i_L, v_Cvalues from the RLC filter. The control logic selects one of multiple possible logic states q based on whether the sensed i_L, v_Cvalues belongs one of multiple boundary regions of a tracking band in an i_L, v_Cstate space.
FILED	Tuesday, December 19, 2017
APPL NO	15/846938
ART UNIT	2838 — Electrical Circuits and Systems
CURRENT CPC	Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/53871 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10264212 — Low-complexity deinterlacing with motion detection and overlay compensation

US 10264212	Fleizach
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Gregory Knowles Fleizach (San Diego, California)
ASSIGNEE(S)	The United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Gregory Knowles Fleizach (San Diego, California)
ABSTRACT	A method and system for deinterlacing. A memory receives a current input image frame and a next input image frame. A processor estimates motion between the current input image frame and the next input image frame. Based on the motion estimate, a deinterlace map is created that indicates where the current input image frame should be deinterlaced. The current input image frame is split into fields, the first frame being an odd field frame, the second frame being an even field frame. The processor interpolates missing lines in the image. Two deinterlaced frames are output, with the first deinterlaced frame being based on the odd field frame and the second deinterlaced frame being based on the even field frame.
FILED	Wednesday, June 27, 2018
APPL NO	16/020264
ART UNIT	2422 — Cable and Television
CURRENT CPC	Pictorial Communication, e.g Television H04N 7/014 (20130101) H04N 7/0137 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10264407 — Intelligent multi-bean medium access control in ku-band for mission-oriented mobile mesh networks

US 10264407	Hu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama); San Diego State University (SDSU) Foundation (San Diego, California)
ASSIGNEE(S)	The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama); San Diego State University (SDSU) Foundation (San Diego, California)
INVENTOR(S)	Fei Hu (Tuscaloosa, Alabama); Xin Li (Tuscaloosa, Alabama); Sunil Kumar (San Diego, California)
ABSTRACT	A MAC design for Ku-band mobile wireless mesh network with multi-beam smart antennas is disclosed. This MAC includes an overlay control that separates the collision domain. It also has lower layer CSMA-like scheme. The disclosed design includes an enhanced PCF and an enhanced DCF for two purposes: (1) exploiting multi-beam concurrent communication capability (2) supporting QoS and mission-based communications. An efficient time synchronization scheme is also disclosed to ensure all beams can concurrently send data to the star node. Finally, ARMA or HMM based prediction schemes are disclosed to predict future traffic profile in each beam. This helps the star node to better prepare the queue content and schedule information.
FILED	Monday, June 27, 2016
APPL NO	15/193617
ART UNIT	2474 — Multiplex and VoIP
CURRENT CPC	Electric Digital Data Processing G06F 9/00 (20130101) Transmission H04B 7/0617 (20130101) H04B 7/2643 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 47/50 (20130101) Wireless Communication Networks H04W 4/046 (20130101) Original (OR) Class H04W 28/0268 (20130101) H04W 74/0808 (20130101) H04W 84/005 (20130101) H04W 84/06 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10264525 — Energy efficient communications

US 10264525	Pratt et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	University of Notre Dame du Lac (South Bend, Indiana)
ASSIGNEE(S)	University of Notre Dame du Lac (South Bend, Indiana)
INVENTOR(S)	Thomas G. Pratt (Niles, Michigan); Jun Chen (South Bend, Indiana)
ABSTRACT	Systems and methods for performing energy efficient communication. A transceiver for use in a point-to-point packet-based communication link with packet erasures is described. The transceiver can include a data source to provide bits of data for transmission to a remote device. The transceiver can map the bits of data to symbols in a constellation according to a modulation scheme and can provide the symbols on one or more subcarriers. The transceiver can include co-located orthogonally polarized antenna elements or spatially separated antenna elements or both. The symbols can be transmitted in packets via one or more of the antenna elements. The transceiver can determine a metric of average transmit energy per bit successfully decoded, and not erased, at the remote device and can adjust transmission powers at the antenna elements to reduce the average transmit energy per successfully decoded and unerased bit.
FILED	Tuesday, November 17, 2015
APPL NO	14/944109
ART UNIT	2465 — Multiplex and VoIP
CURRENT CPC	Transmission H04B 7/10 (20130101) H04B 7/0434 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/00 (20130101) H04L 5/0051 (20130101) H04L 69/22 (20130101) Wireless Communication Networks H04W 28/04 (20130101) H04W 40/16 (20130101) H04W 52/0209 (20130101) Original (OR) Class H04W 92/18 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 70/00 (20180101) Y02D 70/22 (20180101) Y02D 70/144 (20180101) Y02D 70/442 (20180101) Y02D 70/444 (20180101)
VIEW PATENT	@ USPTO: Full Text PDF

10264669 — Flexible electronic assemblies with embedded electronic devices and methods for their fabrication

US 10264669	Lewis et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Research Triangle Institute (Research Triangle Park, North Carolina)
ASSIGNEE(S)	Research Triangle Institute (Research Triangle Park, North Carolina)
INVENTOR(S)	Jay Lewis (Durham, North Carolina); Dorota Temple (Cary, North Carolina); Erik Vick (Raleigh, North Carolina); Ethan Klem (Durham, North Carolina)
ABSTRACT	A flexible electronic assembly includes a flexible current-carrying device, an electrically insulating flexible substrate, and an electronic device embedded in the substrate. The electronic device is mounted face-down on the current-carrying device such that a contact side or component side of the electronic device faces the current-carrying device and is positioned at an interface between the current-carrying device and the substrate. The current-carrying device, substrate, and electronic device are co-planar at the interface. This configuration enables the flexible electronic assembly to have an ultra-thin thickness, for example on the order of micrometers.
FILED	Thursday, April 28, 2016
APPL NO	15/141149
ART UNIT	2848 — Electrical Circuits and Systems
CURRENT CPC	Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/028 (20130101) Original (OR) Class H05K 1/115 (20130101) H05K 1/185 (20130101) H05K 3/301 (20130101) H05K 3/4038 (20130101) H05K 3/4602 (20130101) H05K 2201/10522 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Energy (DOE)

10259158 — Method and apparatus for fabricating ceramic and metal components via additive manufacturing with uniform layered radiation drying

US 10259158	Leu et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S)	The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S)	Ming C Leu (Rolla, Missouri); Amir Ghazanfari (Rolla, Missouri); Wenbin Li (Rolla, Missouri); Gregory E. Hilmas (Rolla, Missouri); Robert G Landers (Rolla, Missouri)
ABSTRACT	A freeform extrusion fabrication process for producing three-dimensional ceramic, metal and functionally gradient composite objects, including the steps of filling a plurality of paste sources with a respective plurality of aqueous paste compositions, operationally connecting respective syringes containing respective aqueous paste compositions to a mixing chamber, moving a first aqueous paste composition from a first respective paste source into the mixing chamber, moving a second aqueous paste composition from a second respective paste source into the mixing chamber, mixing the first and second aqueous paste compositions to define a first admixture having a first admixture composition, extruding the first admixture onto a surface to define an extruded layer having a first admixture composition, surrounding the sides of the extruded layer with an oil bath, radiatively drying the extruded layer.
FILED	Friday, April 15, 2016
APPL NO	15/130261
ART UNIT	1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Original (OR) Class B29C 64/124 (20170801) B29C 64/188 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201)
VIEW PATENT	@ USPTO: Full Text PDF

10259788 — Ionic liquids comprising heteraromatic anions

US 10259788	Schneider et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	UNIVERSITY OF NOTRE DAME DU LAC (Notre Dame, Indiana)
ASSIGNEE(S)	University of Notre Dame du Lac (Notre Dame, Indiana)
INVENTOR(S)	William F. Schneider (Granger, Indiana); Joan F. Brennecke (Granger, Indiana); Edward J. Maginn (South Bend, Indiana); Elaine Vazquez (Chicago, Illinois); Burcu Gurkan (South Bend, Indiana); Erica Price (Mishawaka, Indiana); Brett Goodrich (Mishawaka, Indiana)
ABSTRACT	Some embodiments described herein relate to ionic liquids comprising an anion of a heteraromatic compound such as optionally substituted pyrrolide, optionally substituted pyrazolide, optionally substituted indolide, optionally substituted phospholide, or optionally substituted imidazolide. Methods and devices for gas separation or gas absorption related to these ionic liquids are also described herein.
FILED	Thursday, November 02, 2017
APPL NO	15/802360
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/1456 (20130101) B01D 53/1493 (20130101) B01D 2252/30 (20130101) B01D 2257/302 (20130101) B01D 2257/404 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) Heterocyclic Compounds C07D 207/32 (20130101) Original (OR) Class C07D 207/33 (20130101) C07D 207/34 (20130101) C07D 207/46 (20130101) C07D 207/323 (20130101) C07D 207/325 (20130101) C07D 209/08 (20130101) C07D 231/12 (20130101) C07D 233/58 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/5407 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/04 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/326 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/152 (20151101)
VIEW PATENT	@ USPTO: Full Text PDF

10259845 — Peptides whose uptake by cells is controllable

US 10259845	Jiang et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Tao Jiang (Rancho Santa Fe, California); Emilia S. Olson (La Jolla, California); Michael Whitney (San Diego, California); Roger Tsien (La Jolla, California)
ABSTRACT	A generic structure for the peptides of the present invention includes A-X-B-C, where C is a cargo moiety, the B portion includes basic amino acids, X is a cleavable linker sequence, and the A portion includes acidic amino acids. The intact structure is not significantly taken up by cells; however, upon extracellular cleavage of X, the B-C portion is taken up, delivering the cargo to targeted cells. Cargo may be, for example, a contrast agent for diagnostic imaging, a chemotherapeutic drug, or a radiation-sensitizer for therapy. X may be cleaved extracellularly or intracellularly. The molecules of the present invention may be linear, cyclic, branched, or have a mixed structure.
FILED	Monday, June 29, 2015
APPL NO	14/753975
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0095 (20130101) A61K 47/64 (20170801) A61K 47/65 (20170801) A61K 47/645 (20170801) A61K 49/14 (20130101) A61K 49/0032 (20130101) A61K 49/0043 (20130101) A61K 49/0056 (20130101) A61K 49/085 (20130101) A61K 49/146 (20130101) A61K 51/088 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 14/00 (20130101) C07K 14/4728 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260058 — Beta-glucosidase variants polynucleotides encoding same

US 10260058	Wogulis et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Novozymes, Inc. (Davis, California)
ASSIGNEE(S)	Novozymes, Inc. (Davis, California)
INVENTOR(S)	Mark Wogulis (Davis, California); Paul Harris (Carnation, Washington); David Osborn (Sacramento, California)
ABSTRACT	The present invention relates to beta-glucosidase variants, e.g., beta-glucosidase variants of a parent Family GH3A beta-glucosidase from Aspergillus fumigatus. The present invention also relates to polynucleotides encoding the beta-glucosidase variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the beta-glucosidase variants.
FILED	Thursday, June 08, 2017
APPL NO	15/617296
ART UNIT	1663 — Plants
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2445 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/14 (20130101) Enzymes C12Y 302/01021 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260156 — System and process for electrochemical upgrading of bio-oils and biocrudes

US 10260156	Lilga et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	BATTELLE MEMORIAL INSTITUTE (Richland, Washington); BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho)
ASSIGNEE(S)	BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
INVENTOR(S)	Michael A. Lilga (Richland, Washington); Asanga B. Padmaperuma (Richland, Washington); Tedd E. Lister (Idaho Falls, Idaho); Eric J. Dufek (Ammon, Idaho); Lucia M. Petkovic (Idaho Falls, Idaho); Luis A. Diaz-Aldana (Idaho Falls, Idaho)
ABSTRACT	A system and process are disclosed for electrochemically upgrading bio-oils and bio-crudes that enhance yields of selected reduction products for subsequent production of bio-based fuels.
FILED	Wednesday, March 23, 2016
APPL NO	15/078784
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	General Methods of Organic Chemistry; Apparatus Therefor C07B 31/00 (20130101) Acyclic or Carbocyclic Compounds C07C 1/24 (20130101) C07C 1/24 (20130101) C07C 11/02 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 3/04 (20130101) Original (OR) Class C25B 9/04 (20130101) C25B 9/08 (20130101) C25B 15/02 (20130101) C25B 15/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/366 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260430 — GDCI cold start and catalyst light off

US 10260430	Moore
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados)
ASSIGNEE(S)	DELPHI TECHNOLOGIES IP LIMITED (, Barbados)
INVENTOR(S)	Wayne R. Moore (Goodrich, Michigan)
ABSTRACT	A GDCI engine control system includes a heated catalyst in an engine exhaust port that is in close proximity to a combustion chamber and is used to heat rebreathed exhaust gases. The engine more quickly reaches operating temperatures, and emissions are reduced during cold running.
FILED	Monday, July 18, 2016
APPL NO	15/212856
ART UNIT	3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/2013 (20130101) F01N 13/10 (20130101) Internal-combustion Piston Engines; Combustion Engines in General F02B 25/145 (20130101) Controlling Combustion Engines F02D 13/0219 (20130101) Original (OR) Class F02D 41/024 (20130101) F02D 41/1446 (20130101) F02D 41/1447 (20130101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 1/4264 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260761 — Heat dissipation systems with hygroscopic working fluid

US 10260761	Martin
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Energy and Environmental Research Center Foundation (Grand Forks, North Dakota)
ASSIGNEE(S)	Energy and Environmental Research Center Foundation (Grand Forks, North Dakota)
INVENTOR(S)	Christopher L. Martin (Grand Forks, North Dakota)
ABSTRACT	A heat dissipation system apparatus and method of operation using hygroscopic working fluid for use in a wide variety of environments for absorbed water in the hygroscopic working fluid to be released to minimize water consumption in the heat dissipation system apparatus for effective cooling in environments having little available water for use in cooling systems. The system comprises a low-volatility, hygroscopic working fluid to reject thermal energy directly to ambient air. The low-volatility and hygroscopic nature of the working fluid prevents complete evaporation of the fluid and a net consumption of water for cooling, and direct-contact heat exchange allows for the creation of large interfacial surface areas for effective heat transfer. Specific methods of operation prevent the crystallization of the desiccant from the hygrosopic working fluid under various environmental conditions.
FILED	Monday, July 29, 2013
APPL NO	13/953332
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 3/1417 (20130101) Original (OR) Class Steam or Vapour Condensers F28B 9/06 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Come into Direct Contact Without Chemical Interaction F28C 1/14 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260865 — High resolution, non-contact removal rate module for serial sectioning

US 10260865	Madison et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Jonathan D. Madison (Albuquerque, New Mexico); Elizabeth M. Huffman (Cedar Crest, New Mexico)
ABSTRACT	The present invention relates to a metallographic system including a measurement module configured to provide precise differential measurements of a sample after serial sectioning, as well as methods of employing such a module. In particular example, the measurement module provides differential measurement(s) without contacting the surface of a sample, thereby minimizing contamination of the sample surface.
FILED	Thursday, September 14, 2017
APPL NO	15/705178
ART UNIT	2877 — Optics
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/22 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10260969 — Microfabricated magnetostrictive resonator

US 10260969	Pillars et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Jamin Ryan Pillars (Albuquerque, New Mexico); Eric Langlois (Albuquerque, New Mexico); Christian Lew Arrington (Albuquerque, New Mexico); Todd Monson (Albuquerque, New Mexico)
ABSTRACT	A microfabricated magnetic resonator is provided. The microfabricated magnetic resonator has one or more resonator portions, each of which is a magnetoelastic resonating structure having a maximum circumference or maximum linear dimension in at least one direction that is less than 1000 μm. At least one of the resonator portions comprises an electrodeposited material comprising at least a cobalt constituent and an iron constituent.
FILED	Wednesday, October 10, 2018
APPL NO	16/156555
ART UNIT	2827 — Semiconductors/Memory
CURRENT CPC	Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/562 (20130101) C25D 5/02 (20130101) C25D 5/18 (20130101) C25D 7/00 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/125 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10261033 — Material identification system

US 10261033	Jimenez, Jr. et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Edward Steven Jimenez, Jr. (Albuquerque, New Mexico); Kyle R. Thompson (Albuquerque, New Mexico)
ABSTRACT	A method and apparatus for identifying a material in an object. An image of the object generated from energy passing through the object is obtained by a computer system. The computer system estimates attenuations for pixels in a sensor system from the image of the object to form estimated attenuations. The estimated attenuations represent a loss of the energy that occurs from the energy passing through the object. The computer system also identifies the material in the object using the estimated attenuations and known attenuation information for identifying the material in the object.
FILED	Tuesday, January 20, 2015
APPL NO	14/601103
ART UNIT	2863 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) Original (OR) Class Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/00 (20130101) G01V 5/0016 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261042 — Stationary probe rotating disk electrode

US 10261042	Lopes et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S)	UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Pietro Papa Lopes (Lemont, Illinois); Nenad Markovic (Hinsdale, Illinois); Dusan Strmcnik (Woodridge, Illinois); Vojislav Stamenkovic (Naperville, Illinois)
ABSTRACT	A stationary probe having a probe holder and a probe with a probe tip. The stationary probe may be part of a stationary probe rotating disk electrode wherein the stationary probe has a passage therethrough for rotatably receiving a rotating disk electrode comprising a rotating shaft, rotatable about a longitudinal axis, and having an electrode portion extending therefrom configured to receive an electrode. The stationary probe rotating disk electrode may be part of an analytical system wherein the probe tip includes a capillary entrance spaced apart from the electrode and connected to an analyte flow path.
FILED	Thursday, September 29, 2016
APPL NO	15/280878
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/30 (20130101) G01N 27/283 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10261049 — Aerosol ionizer

US 10261049	Brechtel et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Brechtel Manufacturing, Inc. (Hayward, California)
ASSIGNEE(S)	Brechtel Manufacturing, Inc. (Hayward, California)
INVENTOR(S)	Fredrick J Brechtel (Berkeley, California); Xerxes Lopez-Yglesias (Hayward, California)
ABSTRACT	A system and method comprising an ion production chamber having an ultra-violet light source disposed towards said chamber, a coated quartz plate between the chamber and the UV source whose coating absorbs incident UV light and ejects electrons into the chamber through the photoelectric effect, a harvest gas disposed to flow through the chamber from an inlet to an outlet, and a jet operable to introduce a sample into the harvest gas flow. In some embodiments the system includes using helium as the harvest gas. Certain embodiments include introducing a sample perpendicular to the harvest gas flow and using multiple sample introduction jets to increase mixing efficiency. In some embodiments the harvest gas and particle sample jet are one and the same. The charge sample may be coupled to a MEMS-based electrometer.
FILED	Wednesday, July 11, 2018
APPL NO	16/032874
ART UNIT	2881 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/66 (20130101) Original (OR) Class G01N 27/624 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 29/24 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 27/02 (20130101) H01J 49/145 (20130101) H01J 49/161 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261078 — Shear horizontal surface acoustic wave (SH-SAW) resonators and arrays thereof

US 10261078	Branch et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Darren W. Branch (Albuquerque, New Mexico); Thayne L. Edwards (Bend, Oregon)
ABSTRACT	The present application relates to a biosensor that employs an acoustic cavity to store mechanical energy. In particular examples, the biosensor includes an electrode region and one or more reflector regions to form the acoustic cavity, as well as a functionalized active area disposed in proximity to the cavity. Methods of making and using such biosensors are also described herein.
FILED	Tuesday, August 16, 2016
APPL NO	15/238361
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2300/168 (20130101) B01L 2300/0645 (20130101) B01L 2400/0436 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/022 (20130101) G01N 29/036 (20130101) G01N 33/5438 (20130101) Original (OR) Class G01N 2291/0255 (20130101) G01N 2291/0256 (20130101) G01N 2291/0423 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/02685 (20130101) H03H 9/14552 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261120 — Arc plasma-generating systems and methods thereof

US 10261120	Schindelholz et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Eric John Schindelholz (Albuquerque, New Mexico); Kenneth Miguel Armijo (Albuquerque, New Mexico); Jay Johnson (Albuquerque, New Mexico); Richard Karl Harrison (Albuquerque, New Mexico); Benjamin Bing-Yeh Yang (Atlanta, Georgia)
ABSTRACT	The present invention relates to systems for generating an arc fault in an electrical circuit, as well as methods thereof. In particular, the system provides a platform that can produce an arc discharge in a controlled manner, while measuring various parameters to characterize that discharge. Such parameters include voltage measurements, current measurements, optical spectroscopy measurements, electron temperatures, and/or plasma temperatures.
FILED	Wednesday, May 24, 2017
APPL NO	15/603782
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/025 (20130101) Original (OR) Class G01R 31/2846 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261916 — Adaptive extension of leases for entries in a translation lookaside buffer

US 10261916	Awad et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Advanced Micro Devices, Inc. (Sunnyvale, California)
ASSIGNEE(S)	ADVANCED MICRO DEVICES, INC. (Santa Clara, California)
INVENTOR(S)	Amro Awad (Albuquerque, New Mexico); Sergey Blagodurov (Seattle, Washington); Arkaprava Basu (Austin, Texas); Mark H. Oskin (Bellevue, Washington); Gabriel H. Loh (Bellevue, Washington); Andrew G. Kegel (Bellevue, Washington); David S. Christie (Austin, Texas); Kevin J. McGrath (Sunnyvale, California)
ABSTRACT	The described embodiments include a computing device with two or more translation lookaside buffers (TLB). During operation, the computing device updates an entry in the TLB based on a virtual address to physical address translation and metadata from a page table entry that were acquired during a page table walk. The computing device then computes, based on a lease length expression, a lease length for the entry in the TLB. Next, the computing device sets, for the entry in the TLB, a lease value to the lease length, wherein the lease value represents a time until a lease for the entry in the TLB expires, wherein the entry in the TLB is invalid when the associated lease has expired. The computing device then uses the lease value to control operations that are allowed to be performed using information from the entry in the TLB.
FILED	Friday, November 25, 2016
APPL NO	15/361335
ART UNIT	2137 — Memory Access and Control
CURRENT CPC	Electric Digital Data Processing G06F 12/1009 (20130101) G06F 12/1027 (20130101) G06F 12/1036 (20130101) Original (OR) Class G06F 2212/65 (20130101) G06F 2212/683 (20130101) G06F 2212/1024 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10262000 — Global distributed file append using log-structured file system

US 10262000	Bent et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	EMC Corporation (Hopkinton, Massachusetts)
ASSIGNEE(S)	EMC Corporation (Hopkinton, Massachusetts); Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	John M. Bent (Los Alamos, New Mexico); Sorin Faibish (Newton, Massachusetts); Gary Grider (Los Alamos, New Mexico); Aaron Torres (Los Alamos, New Mexico)
ABSTRACT	Techniques are provided for globally appending data from a group of distributed processes to a shared file using a log-structured file system. Data generated by a plurality of processes in a parallel computing system are appended to a shared file by storing the data to the shared file using a log-structured file system (such as a Parallel Log-Structured File System (PLFS)); and generating an index entry for the data, the index entry comprising a logical offset entry and a timestamp entry indicating a time of the storage, wherein the logical offset entry is resolved at read time. The logical offset entry can be populated with an append placeholder that is resolved when the shared file is read. At read time, a plurality of the index entries associated with the shared file can be sorted using the timestamp entry to deliver the requested shared file to a requesting application.
FILED	Wednesday, June 19, 2013
APPL NO	13/921657
ART UNIT	2161 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 17/3007 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10262098 — Field programmable gate array bitstream verification

US 10262098	Hamlet
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Jason Hamlet (Albuquerque, New Mexico)
ABSTRACT	Described herein are various technologies pertaining to confirming an integrity of a FPGA. A verifier circuit is placed into an FPGA bitstream to enable external verification of the FPGA configuration in real time without requiring readout of the FPGA configuration itself. Number generators are utilized to generate a key which is shared between the FPGA and an external verification component (VC). The key is utilized to configure an initial state of sequence registers respectively located on both the FPGA and the VC. When the FPGA is operating with an approved configuration, output from the sequence registers at the FPGA and the VC are the same.
FILED	Thursday, October 29, 2015
APPL NO	14/927046
ART UNIT	2851 — Printing/Measuring and Testing
CURRENT CPC	Electric Digital Data Processing G06F 17/5081 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10262428 — System and method for adaptive range 3D scanning

US 10262428	Rosman et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) National Nuclear Security Administration (NNSA)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Guy Rosman (Newton, Massachusetts); Daniela Rus (Weston, Massachusetts); John W. Fisher, III (Chestnut Hill, Massachusetts)
ABSTRACT	A scanner system is configured for acquiring three dimensional image information of an object. The scanner includes a projector, a camera, a graphics processing device, and a processor. The projector projects one of several pre-defined patterns upon the object. The camera captures an image from the object, which is received by the processor. The processor approximates mutual information from the object and the pattern using the graphics processing device, and selects a second pattern for projecting on the object.
FILED	Friday, April 07, 2017
APPL NO	15/482375
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/2518 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/2036 (20130101) G06K 2209/40 (20130101) Image Data Processing or Generation, in General G06T 7/521 (20170101) Original (OR) Class G06T 17/05 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10262784 — Ceramic insulated transformer

US 10262784	Cioffi et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Philip Michael Cioffi (Schaghticoke, New York); Qin Chen (Schenectady, New York); Wei Zhang (Ballston Lake, New York); Ravisekhar Nadimpalli Raju (Clifton Park, New York)
ABSTRACT	A transformer includes a ceramic housing, a primary winding disposed within the housing, a secondary winding disposed outside the winding, and a core extending through a first aperture in the housing. The housing includes a first portion and a second portion. Each of the first and second portions include a planar structure having a first housing aperture, and a plurality of sidewalls extending perpendicular to the planar structure along a plurality of edges of the planar structure. The first and second portions interface with one another when the ceramic housing is assembled such that the sidewalls of the first and second portions overlap with one another.
FILED	Tuesday, January 10, 2017
APPL NO	15/402962
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/02 (20130101) Original (OR) Class H01F 27/24 (20130101) H01F 27/29 (20130101) H01F 27/32 (20130101) H01F 41/061 (20160101) H01F 41/125 (20130101) H01F 41/0206 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10262931 — Lateral vias for connections to buried microconductors and methods thereof

US 10262931	Adams et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Scott Silverman (San Marcos, California)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Varioscale, Inc. (San Marcos, California)
INVENTOR(S)	David P. Adams (Albuquerque, New Mexico); Kira L. Fishgrab (Albuquerque, New Mexico); Karl Douglas Greth (Albuquerque, New Mexico); Michael David Henry (Albuquerque, New Mexico); Jeffrey Stevens (Albuquerque, New Mexico); V. Carter Hodges (Albuquerque, New Mexico); Randy J. Shul (Albuquerque, New Mexico); Ronald S. Goeke (Albuquerque, New Mexico); Robert K. Grubbs (Boise, Idaho); Scott Silverman (San Marcos, California)
ABSTRACT	The present invention relates to a lateral via to provide an electrical connection to a buried conductor. In one instance, the buried conductor is a through via that extends along a first dimension, and the lateral via extends along a second dimension that is generally orthogonal to the first dimension. In another instance, the second dimension is oblique to the first dimension. Components having such lateral vias, as well as methods for creating such lateral vias are described herein.
FILED	Tuesday, May 15, 2018
APPL NO	15/980546
ART UNIT	2813 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/486 (20130101) H01L 21/4803 (20130101) H01L 21/4853 (20130101) H01L 21/76898 (20130101) H01L 23/147 (20130101) H01L 23/481 (20130101) H01L 23/3121 (20130101) H01L 23/5384 (20130101) H01L 23/5386 (20130101) H01L 23/49822 (20130101) H01L 23/49827 (20130101) Original (OR) Class H01L 24/13 (20130101) H01L 24/16 (20130101) H01L 24/25 (20130101) H01L 25/065 (20130101) H01L 2224/13009 (20130101) H01L 2224/13101 (20130101) H01L 2224/13101 (20130101) H01L 2224/16145 (20130101) H01L 2224/16225 (20130101) H01L 2224/25105 (20130101) H01L 2924/00014 (20130101) H01L 2924/014 (20130101) H01L 2924/15311 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263136 — Direct band gap group IV semiconductors and methods of preparing the same

US 10263136	Yoo
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Jinkyoung Yoo (Los Alamos, New Mexico)
ABSTRACT	A semiconductor film includes a two-dimensional (2D) material layer having a hexagonal in-plane lattice structure, and a substantially planar Group IV semiconductor layer having a direct band gap on the 2D material layer. A method of fabricating a semiconductor material includes growing a Group IV semiconductor material on a two-dimensional material having a hexagonal in-plane lattice structure. This growth process results in the Group IV semiconductor material having a direct band gap. The semiconductor films may be used in any optoelectronic device, including flexible devices.
FILED	Wednesday, October 25, 2017
APPL NO	15/793804
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/602 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0234 (20130101) H01L 21/02381 (20130101) H01L 21/02433 (20130101) H01L 21/02527 (20130101) H01L 21/02609 (20130101) H01L 31/1816 (20130101) Original (OR) Class H01L 33/34 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263186 — Bulk heterojunction organic photovoltaic cells made by glancing angle deposition

US 10263186	Forrest et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Stephen R. Forrest (Ann Arbor, Michigan); Ning Li (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Stephen R. Forrest (Ann Arbor, Michigan); Ning Li (Ann Arbor, Michigan)
ABSTRACT	A method of making a bulk heterojunction organic photovoltaic cell by glancing angle deposition. As the disclosed method relies on a trajectory of incident vapor flux that is not parallel to the substrate normal, micro and nano-scale columnar structures of thin films can be grown on the substrate. There is also disclosed a method of forming a donor-acceptor heterojunction by depositing at least one additional organic material over the columnar structures.
FILED	Tuesday, July 27, 2010
APPL NO	12/843949
ART UNIT	2817 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0008 (20130101) H01L 51/0012 (20130101) Original (OR) Class H01L 51/0046 (20130101) H01L 51/424 (20130101) H01L 51/4253 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263241 — Electroless process for depositing refractory metals

US 10263241	Small et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Leo J. Small (Albuquerque, New Mexico); Paul G. Clem (Albuquerque, New Mexico); Erik David Spoerke (Albuquerque, New Mexico)
ABSTRACT	The invention provides an inexpensive, scalable process for coating materials with a film of a refractory metal. As an example, the immersion process can comprise the deposition of a sacrificial zinc coating which is galvanically displaced by the ether-mediated reduction of oxophilic WCl₆to form a complex WO_xCl_yfilm, and subsequently annealed to crystalline, metallic tungsten. The efficacy of this process was demonstrated on a carbon foam electrode, showing a 50% decrease in electrode resistance and significant gains in electrochemical performance. This process enables voltage efficiency gains for electrodes in batteries, redox flow batteries, and industrial processes where high conductivity and chemical stability are paramount.
FILED	Friday, December 09, 2016
APPL NO	15/374775
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/54 (20130101) C23C 18/1696 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0404 (20130101) Original (OR) Class H01M 4/0452 (20130101) H01M 4/0471 (20130101) H01M 4/663 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263246 — Lithiated and passivated lithium ion battery anodes

US 10263246	Dudney et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Nancy J. Dudney (Knoxville, Tennessee); Edward W. Hagaman (Oliver Springs, Tennessee); Gabriel M. Veith (Knoxville, Tennessee); Lance W. Gill (Oak Ridge, Tennessee); Robert L. Sacci (Ringgold, Georgia)
ABSTRACT	An electrode material includes a lithium active material composition. The lithium active material composition includes lithium and an active anode material. The lithium active material composition is coated with a lithium ion conducting passivating material, such that the electrode material is lithiated and pre-passivated. An electrode and a battery are also disclosed. Methods of making an electrode material, electrode and battery that are lithiated and pre-passivated are also disclosed.
FILED	Friday, November 20, 2015
APPL NO	14/947687
ART UNIT	1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/62 (20130101) H01M 4/133 (20130101) Original (OR) Class H01M 4/139 (20130101) H01M 4/366 (20130101) H01M 4/0404 (20130101) H01M 4/0445 (20130101) H01M 4/587 (20130101) H01M 4/622 (20130101) H01M 10/058 (20130101) H01M 10/0525 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263277 — Flexible thin film solid state lithium ion batteries

US 10263277	Pitts et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	John Roland Pitts (Lakewood, Colorado); Se-Hee Lee (Louisville, Colorado); C. Edwin Tracy (Golden, Colorado)
ASSIGNEE(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S)	John Roland Pitts (Lakewood, Colorado); Se-Hee Lee (Louisville, Colorado); C. Edwin Tracy (Golden, Colorado)
ABSTRACT	Exemplary flexible thin film solid state lithium ion batteries (10) and methods for making the same are disclosed. An exemplary flexible solid state thin film electrochemical device (10) may include a flexible substrate (12), first (14) and second electrodes (18), and an electrolyte (16) disposed between the first (14) and second electrodes (18). The electrolyte (16) is disposed on the flexible substrate (12). The first electrode (14) is disposed on the electrolyte (16), and the second electrode (18) having been buried between the electrolyte (16) and the substrate (12).
FILED	Monday, February 25, 2008
APPL NO	12/808459
ART UNIT	1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/0438 (20130101) H01M 4/1391 (20130101) H01M 10/052 (20130101) Original (OR) Class H01M 10/0436 (20130101) H01M 10/0585 (20130101) H01M 2300/0065 (20130101) H01M 2300/0094 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49115 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

10263308 — Solar flow battery

US 10263308	McKone et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S)	CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S)	James R. McKone (Ithaca, New York); Hector D. Abruna (Ithaca, New York)
ABSTRACT	A solar flow battery comprising: a positive compartment containing at least one positive electrode in contact with a positive electrolyte containing a first redox active molecule; a negative compartment containing at least one negative electrode in contact with a negative electrolyte containing a second redox active molecule, wherein said first and second redox active molecules remain dissolved in solution when changed in oxidation state; at least one of said negative or positive electrodes comprises a semiconductor light absorber; electrical communication means between said electrodes and an external load for directing electrical energy into or out of said solar flow battery; a separator component that separates the positive and negative electrolytes while permitting the passage of non-redox-active species; and means for establishing flow of the positive and negative electrolyte solutions past respective electrodes. Methods of using the solar flow battery for storing and releasing electrical energy are also described.
FILED	Monday, March 23, 2015
APPL NO	15/128321
ART UNIT	2851 — Printing/Measuring and Testing
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/053 (20141201) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) H01M 14/005 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/355 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263447 — Secondary battery management system

US 10263447	MirTabatabaei et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Robert Bosch GmbH (Stuttgart, Germany)
ASSIGNEE(S)	Robert Bosch GmbH (Stuttgart, Germany)
INVENTOR(S)	Anahita MirTabatabaei (San Francisco, California); Reinhardt Klein (Mountain View, California); Ashish Krupadanam (Cupertino, California); Nikhil Ravi (Mountain View, California); John F. Christensen (Elk Grove, California)
ABSTRACT	A method and system for managing a battery system. The method including receiving at least one measured characteristic of the battery over a pre-defined time horizon from the at least one sensor, receiving at least one estimated characteristic of the battery from a electrochemical-based battery model based on differential algebraic equations, determining a cost function of a Moving Horizon Estimation based on the at least one measured characteristic and the at least one estimated characteristic, updating the electrochemical-based battery model based on the cost function, estimating at least one state of the at least one battery cell by applying the electrochemical-based battery model, and regulating at least one of charging or discharging of the battery based on the estimation of the at least one state of the at least one battery cell.
FILED	Friday, January 29, 2016
APPL NO	15/011148
ART UNIT	2859 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3606 (20130101) G01R 31/3655 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/44 (20130101) H01M 10/48 (20130101) H01M 10/052 (20130101) H01M 10/425 (20130101) H01M 10/4257 (20130101) H01M 2010/4271 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/007 (20130101) Original (OR) Class H02J 7/0021 (20130101) H02J 7/0072 (20130101) H02J 2007/0095 (20130101) H02J 2007/0098 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263786 — Intelligent sensor and controller framework for the power grid

US 10263786	Akyol et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Bora A. Akyol (Richland, Washington); Jereme Nathan Haack (West Richland, Washington); Philip Allen Craig, Jr. (West Richland, Washington); Cody William Tews (Richland, Washington); Anand V. Kulkarni (Richland, Washington); Brandon J. Carpenter (Kennewick, Washington); Wendy M. Maiden (Pasco, Washington); Selim Ciraci (Richland, Washington)
ABSTRACT	Disclosed below are representative embodiments of methods, apparatus, and systems for monitoring and using data in an electric power grid. For example, one disclosed embodiment comprises a sensor for measuring an electrical characteristic of a power line, electrical generator, or electrical device; a network interface; a processor; and one or more computer-readable storage media storing computer-executable instructions. In this embodiment, the computer-executable instructions include instructions for implementing an authorization and authentication module for validating a software agent received at the network interface; instructions for implementing one or more agent execution environments for executing agent code that is included with the software agent and that causes data from the sensor to be collected; and instructions for implementing an agent packaging and instantiation module for storing the collected data in a data container of the software agent and for transmitting the software agent, along with the stored data, to a next destination.
FILED	Friday, January 19, 2018
APPL NO	15/875959
ART UNIT	2491 — Cryptography and Security
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 19/2513 (20130101) Electric Digital Data Processing G06F 21/44 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3247 (20130101) Original (OR) Class H04L 63/08 (20130101) H04L 63/123 (20130101) H04L 63/126 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 40/24 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

National Science Foundation (NSF)

10258364 — System and method for laparoscopic morcellator

US 10258364	Isakov et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S)	THE BRIGHAM AND WOMEN'S HOSPITAL (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S)	Alexander Isakov (Sudbury, Massachusetts); Kimberly Murdaugh (Cambridge, Massachusetts); William Burke (Sudbury, Massachusetts); Jon Einarsson (Boston, Massachusetts); Conor Walsh (Cambridge, Massachusetts)
ABSTRACT	Embodiments of the invention provide a laparoscopic morcellating device and method for removing tissue from a body cavity. The morcellating device includes a containment mechanism having an aperture, a cutting mechanism designed to fit into an interior space of the containment mechanism and a retractor mechanism that is coupled to the cutting mechanism. The containment mechanism and cutting mechanism combination surrounds the tissue and the aperture of the containment mechanism is closed around the tissue. The morcellating device further includes a motor for actuating the retractor such that the cutting mechanism constricts and morcellates the tissue. The laparoscopic morcellating device further allows for torque balancing of the retractor mechanism, gas flow regulation of the body cavity, and safety feedback mechanisms that can alert the surgeon.
FILED	Wednesday, March 05, 2014
APPL NO	14/775053
ART UNIT	3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/221 (20130101) A61B 17/3421 (20130101) A61B 17/32002 (20130101) A61B 17/32056 (20130101) Original (OR) Class A61B 17/320016 (20130101) A61B 2017/0003 (20130101) A61B 2017/00075 (20130101) A61B 2017/00123 (20130101) A61B 2017/00287 (20130101) A61B 2017/00398 (20130101) A61B 2017/00876 (20130101) A61B 2017/2212 (20130101) A61B 2017/320024 (20130101) A61B 2090/0811 (20160201)
VIEW PATENT	@ USPTO: Full Text PDF

10258563 — Encapsulation of microbubbles within the aqueous core of microcapsules

US 10258563	Wrenn et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Steven P. Wrenn (Swarthmore, Pennsylvania); Stephen Dicker (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S)	Steven P. Wrenn (Swarthmore, Pennsylvania); Stephen Dicker (Philadelphia, Pennsylvania)
ABSTRACT	The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject.
FILED	Tuesday, April 20, 2010
APPL NO	13/264335
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10258985 — Formation and control of fluidic species

US 10258985	Link et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Darren Roy Link (Lexington, Massachusetts); David A. Weitz (Bolton, Massachusetts); Manuel Marquez-Sanchez (Lincolnshire, Illinois); Zhengdong Cheng (College Station, Texas)
ABSTRACT	This invention generally relates to systems and methods for the formation and/or control of fluidic species, and articles produced by such systems and methods. In some cases, the invention involves unique fluid channels, systems, controls, and/or restrictions, and combinations thereof. In certain embodiments, the invention allows fluidic streams (which can be continuous or discontinuous, i.e., droplets) to be formed and/or combined, at a variety of scales, including microfluidic scales. In one set of embodiments, a fluidic stream may be produced from a channel, where a cross-sectional dimension of the fluidic stream is smaller than that of the channel, for example, through the use of structural elements, other fluids, and/or applied external fields, etc. In some cases, a Taylor cone may be produced. In another set of embodiments, a fluidic stream may be manipulated in some fashion, for example, to create tubes (which may be hollow or solid), droplets, nested tubes or droplets, arrays of tubes or droplets, meshes of tubes, etc. In some cases, droplets produced using certain embodiments of the invention may be charged or substantially charged, which may allow their further manipulation, for instance, using applied external fields. Non-limiting examples of such manipulations include producing charged droplets, coalescing droplets (especially at the microscale), synchronizing droplet formation, aligning molecules within the droplet, etc. In some cases, the droplets and/or the fluidic streams may include colloids, cells, therapeutic agents, and the like.
FILED	Thursday, March 19, 2015
APPL NO	14/662668
ART UNIT	3752 — Fluid Handling and Dispensing
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 5/0682 (20130101) B01F 13/0062 (20130101) B01F 13/0071 (20130101) B01F 13/0076 (20130101) B01F 2215/0431 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2/04 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 3/502784 (20130101) Original (OR) Class B01L 2200/0673 (20130101) B01L 2300/0867 (20130101) B01L 2400/02 (20130101) B01L 2400/0415 (20130101) B01L 2400/0424 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 5/03 (20130101) B05B 7/061 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258987 — Fluid infection using acoustic waves

US 10258987	Weitz et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); The University Court of the University of Glasgow (Glasgow, United Kingdom)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); The University Court of the University of Glasgow (Glasgow, United Kingdom)
INVENTOR(S)	David A. Weitz (Bolton, Massachusetts); Thomas Franke (Augsburg, Germany)
ABSTRACT	The present invention generally relates to the manipulation of fluids using acoustic waves such as surface acoustic waves. In some aspects, one fluid may be introduced into another fluid via application of suitable acoustic waves. For example, a fluid may be added or injected into another fluid by applying acoustic waves where, in the absence of the acoustic waves, the fluid cannot be added or injected, e.g., due to the interface or surface tension between the fluids. Thus, for example, a fluid may be injected into a droplet of another fluid. Other embodiments of the invention are generally directed to systems and methods for making or using such systems, kits involving such systems, or the like.
FILED	Thursday, June 25, 2015
APPL NO	15/320408
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0819 (20130101) B01F 5/0471 (20130101) B01F 13/0071 (20130101) B01F 15/0241 (20130101) B01F 15/0263 (20130101) B01F 2215/0037 (20130101) B01F 2215/0463 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) B01J 2219/00792 (20130101) B01J 2219/00833 (20130101) B01J 2219/00932 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502776 (20130101) B01L 3/502784 (20130101) Original (OR) Class B01L 2200/16 (20130101) B01L 2200/0647 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) B01L 2400/0436 (20130101) B01L 2400/0439 (20130101) B01L 2400/0487 (20130101) Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8222 (20130101) C12N 15/8243 (20130101) C12N 15/8261 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101)
VIEW PATENT	@ USPTO: Full Text PDF

10259122 — Compliant adaptive robot grasper

US 10259122	Odhner et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Lael Ulam Odhner (Medford, Massachusetts); Leif Patrick Jentoft (Cambridge, Massachusetts); Yaroslav Tenzer (Somerville, Massachusetts)
ABSTRACT	A compliant adaptive robot grasper comprises a multi-bar finger linkage, including a fingertip link, at least one base link, and front and rear links joining the base link via a first set of joints with the fingertip links via a second set of joints. The base link includes a mounting structure, allowing it to be mounted on a mounting block for rotary actuation. Linear connections between the joints form a shape substantially in the form of a parallelogram allowing the linear connections across the front and rear links to remain substantially parallel to one another as the front and rear links pivot about the base link without substantially changing the orientation of the fingertip link until and unless the multi-bar finger linkage contacts an external object.
FILED	Friday, March 04, 2016
APPL NO	15/553358
ART UNIT	3652 — Material and Article Handling
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 13/084 (20130101) B25J 15/0009 (20130101) B25J 15/12 (20130101) B25J 15/022 (20130101) Original (OR) Class B25J 15/024 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259831 — Hydroxide-catalyzed formation of silicon-oxygen bonds by dehydrogenative coupling of hydrosilanes and alcohols

US 10259831	Toutov et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Anton Toutov (Pasadena, California); Kerry Betz (Boulder, Colorado); Andrew M. Romine (Kennett Square, Pennsylvania); Robert H. Grubbs (South Pasadena, California)
ABSTRACT	The present disclosure is directed to methods for dehydrogenatively coupled hydrosilanes and alcohols, the methods comprising contacting an organic substrate having at least one organic alcohol moiety with a mixture of at least one hydrosilane and sodium and/or potassium hydroxide, the contacting resulting in the formation of a dehydrogenatively coupled silyl ether. The disclosure further described associated compositions and methods of using the formed products.
FILED	Tuesday, July 26, 2016
APPL NO	15/219710
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 235/08 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/21 (20130101) C07F 7/0896 (20130101) C07F 7/1804 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10259838 — Methods, compositions, and kits using heterogeneous catalysts

US 10259838	Hill et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	OCCIDENTAL COLLEGE (Los Angeles, California)
ASSIGNEE(S)	OCCIDENTAL COLLEGE (Los Angeles, California)
INVENTOR(S)	Michael Hill (Pasadena, California); Andrew Udit (Glendale, California)
ABSTRACT	Described herein are methods, compositions and kits utilizing heterogeneous metal catalysts for the preparation of cycloaddition compounds, such as triazoles and biomolecules.
FILED	Monday, July 31, 2017
APPL NO	15/664926
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/06 (20130101) B01J 23/72 (20130101) B01J 27/138 (20130101) B01J 31/08 (20130101) B01J 31/26 (20130101) B01J 31/183 (20130101) B01J 35/02 (20130101) B01J 35/0006 (20130101) B01J 35/0073 (20130101) B01J 37/04 (20130101) B01J 37/16 (20130101) B01J 2231/328 (20130101) B01J 2531/16 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Original (OR) Class Peptides C07K 1/1077 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259919 — Perchlorate ion permselective membranes

US 10259919	Huang et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	UNIVERSITY OF DELAWARE (Newark, Delaware)
ASSIGNEE(S)	UNIVERSITY OF DELAWARE (Newark, Delaware)
INVENTOR(S)	Chin-Pao Huang (Hockessin, Delaware); Po-Yen Wang (Broomall, Pennsylvania)
ABSTRACT	A membrane having permselectivity for perchlorate ion is prepared using certain types of quaternary ammonium salts contained in a polymeric matrix material, which may be plasticized. Such membranes are useful in electrodialysis processes, whereby perchlorate-contaminated aqueous compositions are purified.
FILED	Wednesday, September 02, 2015
APPL NO	15/509717
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Separation B01D 61/44 (20130101) B01D 71/30 (20130101) B01D 71/82 (20130101) B01D 2325/42 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4693 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2231 (20130101) Original (OR) Class C08J 2327/06 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260400 — Radio frequency system and method for monitoring engine-out exhaust constituents

US 10260400	Sappok et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	CTS Corporation (Lisle, Illinois)
ASSIGNEE(S)	CTS Corporation (Lisle, Illinois)
INVENTOR(S)	Alexander G. Sappok (Cambridge, Massachusetts); Paul A. Ragaller (Dorchester, Massachusetts); Leslie Bromberg (Sharon, Massachusetts); Andrew D. Herman (Granger, Indiana)
ABSTRACT	A radio frequency system and method for monitoring an engine-out exhaust emission constituent. The system comprises a housing containing the emission constituent, one or more radio frequency sensors extending into the housing and transmitting and receiving radio frequency signals, and a control unit for controlling the radio frequency signals and monitoring changes in the emission constituent based on changes in one or more parameters of the radio frequency signals. In one embodiment, the control unit measures a rate of change in one or more of the parameters of the radio frequency signals for monitoring a rate of change of the emission constituent including for example the emission rate, accumulation rate, and/or depletion rate of the emission constituent.
FILED	Friday, April 07, 2017
APPL NO	15/481670
ART UNIT	2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Separation B01D 53/9422 (20130101) B01D 53/9495 (20130101) B01D 2255/911 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/021 (20130101) F01N 3/208 (20130101) F01N 3/2066 (20130101) F01N 11/00 (20130101) Original (OR) Class F01N 2560/00 (20130101) F01N 2560/12 (20130101) F01N 2560/14 (20130101) F01N 2610/148 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/00 (20130101) G01N 22/04 (20130101) Transmission H04B 17/18 (20150115) H04B 17/309 (20150115) Wireless Communication Networks H04W 24/08 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260486 — Actuation via magnetic torque driven deformation

US 10260486	Mullner et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	BOISE STATE UNIVERSITY (Boise, Idaho)
ASSIGNEE(S)	BOISE STATE UNIVERSITY (Boise, Idaho)
INVENTOR(S)	Peter Mullner (Boise, Idaho); David C. Dunand (Evanston, Illinois); Nikole J. Kucza (Boise, Idaho); Peiqi Zheng (Ramsey, New Jersey)
ABSTRACT	A system may include an actuation member having a first end and a second end. A length of the actuation member is greater than a width of the actuation member. The length extends from the first end to the second end along a longitudinal axis when the actuation member is undeformed. The actuation member may include a magnetic shape memory alloy. The system may further include an anchor retaining the first end of the actuation member. The second end of the actuation member may be free to move laterally to the longitudinal axis in response to a deformation of the actuation member. The system may also include a magnetic field source in proximity to the actuation member. The magnetic field source may be configurable to alter a magnetic field applied to the actuation member to adjust the extent of deformation of the actuation member.
FILED	Friday, March 11, 2016
APPL NO	15/068237
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/065 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10260968 — Polymeric foam deformation gauge

US 10260968	Merrell et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	NANO COMPOSITE PRODUCTS, INC. (Orem, Utah)
ASSIGNEE(S)	Nano Composite Products, Inc. (Orem, Utah)
INVENTOR(S)	Aaron Jake Merrell (Orem, Utah); Anton E. Bowden (Lindon, Utah); David T. Fullwood (Provo, Utah); Brian Anthony Mazzeo (Provo, Utah)
ABSTRACT	In one general aspect, an apparatus includes at least two conductive elements disposed in a polymeric foam and at least two voltage detectors. Each voltage detector is coupled to a respective conductive element and configured to detect a charge generated by an impact to the polymeric foam within a sensing radius of the respective conductive element. In another general aspect, an apparatus includes a deformation sensor and a voltage detector. The deformation sensor includes a conductive element disposed in a polymeric foam, a portion of the conductive element extending beyond an outer wall of the polymeric foam. The voltage detector is coupled to the portion of the conductive element and detects a charge generated by the deformation sensor responsive to an impact to the polymeric foam.
FILED	Friday, August 05, 2016
APPL NO	15/229662
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/04 (20130101) Original (OR) Class G01L 1/06 (20130101) G01L 1/16 (20130101) G01L 1/18 (20130101) G01L 1/20 (20130101) G01L 5/0052 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/37 (20130101) H01L 41/183 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49117 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

10261013 — Robust interferometer and methods of using same

US 10261013	Bornhop et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Darryl J. Bornhop (Nashville, Tennessee); Michael Kammer (Nashville, Tennessee)
ABSTRACT	Provided are improved optical detection systems and methods for using same, which systems and methods comprise single channel interferometric detection systems and methods for determining a characteristic property of samples. Such interferometric detection systems and methods employ a light beam that impinges two or more discrete zones along a channel, thereby avoiding variations that can result in increases in detection limits and/or measurement errors.
FILED	Thursday, June 30, 2016
APPL NO	15/199417
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/45 (20130101) Original (OR) Class G01N 21/75 (20130101) G01N 2021/458 (20130101) G01N 2201/06113 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261084 — Activated GTPase-based assays and kits for the diagnosis of sepsis and other infections

US 10261084	Buranda et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)	STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S)	Tione Buranda (Albuquerque, New Mexico); Jacob Ongudi Agola (Albuquerque, New Mexico); Soumik BasuRay (Dallas, Texas); Scarlett Swanson (Albuquerque, New Mexico); Angela Wandinger-Ness (Albuquerque, New Mexico); Peter C. Simons (Albuquerque, New Mexico); Virginie Bondu (Albuquerque, New Mexico)
ABSTRACT	In one embodiment, the invention provides a method of diagnosing sepsis or a virus-related infection (often a viral hemorrhagic fever infection) in a subject by detecting and measuring the level of a set of sepsis and virus infection-associated-GTPase biomarkers in a sample obtained from the subject using multiplexed flow cytometry. Related kits are also provided. In a preferred embodiment, the invention provides point of care diagnostic methods for determining an early stage sepsis or the severity of a virus infection, especially in a hospital or other setting.
FILED	Thursday, February 19, 2015
APPL NO	14/626536
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/86 (20130101) G01N 33/573 (20130101) Original (OR) Class G01N 2333/914 (20130101) G01N 2800/26 (20130101) G01N 2800/224 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261107 — Scanning resonator microscopy

US 10261107	Dunn
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	University of Kansas (Lawrence, Kansas)
ASSIGNEE(S)	UNIVERSITY OF KANSAS (Lawrence, Kansas)
INVENTOR(S)	Robert Conley Dunn (Lawrence, Kansas)
ABSTRACT	A method of imaging a sample via scanning resonator microscopy is provided comprising positioning a whispering gallery mode (WGM) optical resonator at a first location over the surface of the sample, the WGM optical resonator characterized by at least one resonance frequency, wherein the WGM optical resonator is mounted to the free end of an atomic force microscopy (AFM) cantilever such that the WGM optical resonator moves with the AFM cantilever, and wherein the AFM cantilever is operably coupled to an AFM system configured to provide a topographical image of the sample; evanescently coupling excitation light into the WGM optical resonator; detecting light derived from the excitation light to monitor for a shift in the at least one resonance frequency induced by the surface of the sample; and repeating steps (a)-(c) at least at a second location over the surface of the sample.
FILED	Wednesday, March 30, 2016
APPL NO	15/562499
ART UNIT	2881 — Optics
CURRENT CPC	Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/06 (20130101) Original (OR) Class G01Q 60/22 (20130101) G01Q 60/38 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261298 — Near-infrared-II confocal microscope and methods of use

US 10261298	Hong et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Guosong Hong (Somerville, Massachusetts); Alexander Antaris (Stanford, California); Shuo Diao (Jilin, China PRC); Hongjie Dai (Cupertino, California)
ABSTRACT	Disclosed are methods and devices for confocal microscopy in the near-infrared. wavelength. The device uses a near-infrared (NIR) light producing source such as laser; optical components designed to reflect and transmit NIR from a sample; and an NIR detector coupled to a computer for constructing a focal plane image from a raster scan. The detector may be a photodiode or photo-multiplier tube for detecting fluorescence signals in the NIR (800-1700 nm) wavelength range using a variety of NIR-I (800-1000 nm) and NIR-II (1000-1700 nm) dyes and nanomaterials. An imaging method is described using the NIR-confocal microscope for slice by slice 3D imaging of biological tissues throughout a thickness up to, for example, 5 mm in the NIR-II window. The reduced scattering in NIR-II allows for tissue penetration up to about 5-10 mm, superior to ˜0.2 mm afforded by conventional imaging.
FILED	Tuesday, December 08, 2015
APPL NO	14/962988
ART UNIT	2872 — Optics
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 2021/6439 (20130101) G01N 2223/509 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0036 (20130101) G02B 21/0076 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10261323 — Compact eye-tracked head-mounted display

US 10261323	Hua et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); AUGMENTED VISION, INC (Tucson, Arizona)
ASSIGNEE(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); AUGMENTED VISION INC (Tucson, Arizona)
INVENTOR(S)	Hong Hua (Tuscon, Arizona); Chunyu Gao (Tuscon, Arizona)
ABSTRACT	Eye-tracked head-mounted displays are provide which, in one aspect, may utilize the same optics for eyetracking and image viewing, with a selected portion of the optics used for an eyetracking optical path and a selected portion of the display optics used for an image viewing optical path.
FILED	Wednesday, March 01, 2017
APPL NO	15/446134
ART UNIT	2692 — Selective Visual Display Systems
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 17/086 (20130101) G02B 17/0896 (20130101) G02B 27/017 (20130101) G02B 27/0093 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 2027/011 (20130101) G02B 2027/0138 (20130101) G02B 2027/0187 (20130101) Electric Digital Data Processing G06F 3/013 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261326 — Compact eye-tracked head-mounted display

US 10261326	Hua et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); AUGMENTED VISION, INC (Tucson, Arizona)
ASSIGNEE(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); AUGMENTED VISION INC. (Tucson, Arizona)
INVENTOR(S)	Hong Hua (Tucson, Arizona); Chunyu Gao (Tucson, Arizona)
ABSTRACT	Eye-tracked head-mounted displays are provide which, in one aspect, may utilize the same optics for eyetracking and image viewing, with a selected portion of the optics used for an eyetracking optical path and a selected portion of the display optics used for an image viewing optical path.
FILED	Thursday, December 21, 2017
APPL NO	15/850692
ART UNIT	2692 — Selective Visual Display Systems
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 17/086 (20130101) G02B 17/0896 (20130101) G02B 27/017 (20130101) G02B 27/0093 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 2027/011 (20130101) G02B 2027/0138 (20130101) G02B 2027/0187 (20130101) Electric Digital Data Processing G06F 3/013 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261977 — Resistive memory accelerator

US 10261977	Friedman et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	Eby Friedman (Rochester, New York); Isaac Richter (East Amherst, New York); Xiaochen Guo (Bethlehem, Pennsylvania); Mohammad Kazemi (Rochester, New York); Kamil Pas (Ridgewood, New York); Ravi Patel (Victor, New York); Engin Ipek (Pittsford, New York); Ji Liu (Rochester, New York)
ASSIGNEE(S)	University of Rochester (Rochester, New York)
INVENTOR(S)	Eby Friedman (Rochester, New York); Isaac Richter (East Amherst, New York); Xiaochen Guo (Bethlehem, Pennsylvania); Mohammad Kazemi (Rochester, New York); Kamil Pas (Ridgewood, New York); Ravi Patel (Victor, New York); Engin Ipek (Pittsford, New York); Ji Liu (Rochester, New York)
ABSTRACT	A method includes receiving, by a resistive memory array, a first data, the resistive memory array comprising a plurality of cells, wherein the receiving comprises setting a plurality of resistances on the plurality of cells, wherein each of the plurality of resistances are based on the first data. The method further includes receiving, by the resistive memory array, a second data, wherein the receiving comprises applying at least one of a current and a voltage based on the second data on the plurality of cells. The method still further includes determining, by the resistive memory array, an initial unknown value, the initial value based on the first data and the second data.
FILED	Thursday, May 04, 2017
APPL NO	15/587024
ART UNIT	2824 — Semiconductors/Memory
CURRENT CPC	Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0659 (20130101) G06F 3/0679 (20130101) G06F 17/11 (20130101) G06F 17/16 (20130101) Original (OR) Class Static Stores G11C 7/1006 (20130101) G11C 11/161 (20130101) G11C 13/0004 (20130101) G11C 13/0007 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10262849 — Active stabilization of ion trap radiofrequency potentials

US 10262849	Monroe et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Physics (PHY)
APPLICANT(S)	University of Maryland (College Park, Maryland)
ASSIGNEE(S)	University of Maryland (College Park, Maryland)
INVENTOR(S)	Christopher Monroe (Ellicott City, Maryland); Kale Johnson (Milford, Connecticut); Jaime David Wong-Campos (Hyattsville, Maryland)
ABSTRACT	Disclosed are improved methods and structures for actively stabilizing the oscillation frequency of a trapped ion by noninvasively sampling and rectifying the high voltage RF potential at circuit locations between a step-up transformer and a vacuum feedthrough leading to the ion trap electrodes. We use this sampled/rectified signal in a feedback loop to regulate the RF input amplitude to the circuit. By employing techniques and structures according to the present disclosure we are advantageously able to stabilize a 1 MHz trapped ion oscillation frequency to <10 Hz after 200 s of integration, representing a 34 dB reduction in the level of trap frequency noise and drift, over a locking bandwidth of up to 30 kHz.
FILED	Monday, June 04, 2018
APPL NO	15/997107
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) H01J 49/0027 (20130101) Original (OR) Class H01J 49/422 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263174 — Composite material used as a strain gauge

US 10263174	Merrell et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Brigham Young University (Provo, Utah)
ASSIGNEE(S)	Nano Composite Products, Inc. (Orem, Utah)
INVENTOR(S)	Aaron Jake Merrell (Orem, Utah); David T. Fullwood (Provo, Utah); Anton E. Bowden (Lindon, Utah); Taylor D. Remington (Provo, Utah)
ABSTRACT	In one general aspect, an apparatus comprises a material including a non-layered mixture of an elastomeric polymer with a plurality of voids; and a plurality of conductive fillers disposed in the elastomeric polymer. The apparatus may produce an electrical response to deformation and, thus, function as a strain gauge. The conductive fillers may include conductive nanoparticles and/or conductive stabilizers. In another general aspect, a method of measuring compression strain includes detecting, along a first axis, an electrical response generated in response to an impact to a uniform composite material that includes conductive fillers and voids disposed throughout an elastomeric polymer, and determining a deformation of the impact based on the electrical response. The impact may be along a second axis different from the first axis.
FILED	Friday, March 14, 2014
APPL NO	14/213539
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/16 (20130101) G01L 1/18 (20130101) G01L 1/20 (20130101) G01L 5/0052 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/37 (20130101) H01L 41/183 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49117 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

10263456 — Integrated three-port bidirectional DC-DC converter for renewable energy sources

US 10263456	Wang et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S)	Zhan Wang (Knightdale, North Carolina); Hui Li (Tallahassee, Florida)
ABSTRACT	A three-port bidirectional DC-DC converter for grid-interactive renewable energy source system applications. The three-phase topology is suitable for residential power requirements. The control of the backup battery system and the renewable energy source system are naturally decoupled. In addition, the port interface with the renewable energy is current type, which can implement maximum power point tracking (MPPT) and soft switching under wide variations in the renewable energy source terminal voltage.
FILED	Monday, March 14, 2016
APPL NO	15/069449
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0068 (20130101) H02J 9/06 (20130101) Original (OR) Class Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/24 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263541 — Robust single-phase DC/AC inverter for highly varying DC voltages

US 10263541	Sanfelice et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Electrical and Communications Systems (ECS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Ricardo G. Sanfelice (Santa Cruz, California); Jun Chai (Santa Cruz, California)
ABSTRACT	A single-phase DC/AC inverter has a single-phase inverter bridge with binary switches connected to an RLC low-pass filter. Digital control logic in a control circuit (or in a microcontroller) determines and controls a logic state q determining the position of the switches in the inverter bridge from sensed i_L, v_Cvalues from the RLC filter. The control logic selects one of multiple possible logic states q based on whether the sensed i_L, v_Cvalues belongs one of multiple boundary regions of a tracking band in an i_L, v_Cstate space.
FILED	Tuesday, December 19, 2017
APPL NO	15/846938
ART UNIT	2838 — Electrical Circuits and Systems
CURRENT CPC	Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/53871 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10263592 — Optimal response reflectionless filters

US 10263592	Morgan
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Astronomical Sciences (AST) National Radio Astronomy Observatory (NRAO) Federally Funded Research and Development Center (FFRDC) Operated by Associated Universities, Inc. (AUI)at Charlottesville, VA
APPLICANT(S)	Associated Universities, Inc. (Washington, District of Columbia)
ASSIGNEE(S)	Associated Universities, Inc. (Washington, District of Columbia)
INVENTOR(S)	Matthew Alexander Morgan (Earlysville, Virginia)
ABSTRACT	Reflectionless low-pass, high-pass, band-pass, band-stop, all-pass, all-stop, and multi-band filters, as well as a method for designing such filters is disclosed, along with a method of enhancing the performance of such filters through the use of unmatched sub-networks to realize an optimal frequency response, such as the Chebyshev equal-ripple response. These filters preferably function by absorbing the stop-band portion of the spectrum rather than reflecting it back to the source, which has significant advantages in many different applications. The unmatched sub-networks preferably offer additional degrees of freedom by which element values can be assigned to realize improved cutoff sharpness, stop-band rejection, or other measures of performance.
FILED	Thursday, October 20, 2016
APPL NO	15/298459
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 38/14 (20130101) H01F 2038/143 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/201 (20130101) H01P 1/207 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/06 (20130101) Original (OR) Class H03H 7/38 (20130101) H03H 7/42 (20130101) H03H 7/46 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263722 — Multi-wavelength balanced optical transmission networks

US 10263722	Kilper
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S)	Daniel Kilper (Tucson, Arizona)
ABSTRACT	A method for transmitting data over an optical communication system is performed by sequentially tuning a laser beam among a plurality of optical wavelengths. At least one data signal is modulated onto the plurality of optical wavelengths by sequentially switching the modulation of the data signal among the plurality of optical wavelengths such that at any given time the data signal is only modulated onto a single one of the optical wavelengths. The sequential switching is performed at a rate equal to or greater than a response time of one or more optical amplifiers used for amplifying the optical wavelengths.
FILED	Wednesday, October 14, 2015
APPL NO	15/519400
ART UNIT	2636 — Optical Communications
CURRENT CPC	Transmission H04B 10/516 (20130101) Multiplex Communication H04J 14/0212 (20130101) Original (OR) Class H04J 14/0221 (20130101) Selecting H04Q 11/0005 (20130101) H04Q 2011/0016 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10264334 — End-to-end scheduling for all-optical data centers

US 10264334	Javidi et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Tara Javidi (San Diego, California); Chang-Heng Wang (La Jolla, California)
ABSTRACT	An end-to-end method is provided for scheduling connections for networks such as all-optical data centers, which have a zero in-network buffer and a non-negligible reconfiguration delay in which the rate of schedule reconfiguration is limited to minimize the impact of reduced duty-cycles and to ensure bounded delay without overly restricting the rate of monitoring and decision processes. The method decouples the rate of scheduling from the rate of monitoring. A scheduling algorithm for switches with a reconfiguration delay is used which is based on the well-known MaxWeight scheduling policy. The scheduling policy requires no prior knowledge of traffic load.
FILED	Monday, April 25, 2016
APPL NO	15/137785
ART UNIT	2636 — Optical Communications
CURRENT CPC	Selecting H04Q 11/0005 (20130101) Original (OR) Class H04Q 2011/005 (20130101) H04Q 2011/0033 (20130101) H04Q 2011/0045 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

10257990 — Growing macroalgae at sea

US 10257990	Goudey
FUNDED BY	Department of Commerce (DOC) National Oceanic and Atmospheric Administration (NOAA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Clifford A. Goudey (Newburyport, Massachusetts)
ASSIGNEE(S)
INVENTOR(S)	Clifford A. Goudey (Newburyport, Massachusetts)
ABSTRACT	The present invention provides a practical and economical means of growing of kelp and other types of macroalgae in large quantities on and in the ocean. Through the use of catenary principles and innovative structural designs, efficient designs emerge that translate into lightweight and low-cost components. The novel design described allows cost-efficient macroalgae farming at scales and at depths unsuitable for present macroalgae farming techniques. The device and methods described present a means of farming these seaweeds for the purpose of providing food, chemical feed stocks, and a biomass suitable for the production of biofuels.
FILED	Friday, December 01, 2017
APPL NO	15/829376
ART UNIT	3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 33/00 (20130101) Original (OR) Class Ships or Other Waterborne Vessels; Equipment for Shipping B63B 35/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258027 — Autodissemination of an insect-growth regulator for insect management

US 10258027	Gaugler et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) Small Business Administration (SBA) Small Business Innovation Research (SBIR) Department of Agriculture (USDA) Agricultural Research Service (ARS)
APPLICANT(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S)	Randy Gaugler (North Brunswick, New Jersey); Devi Suman (New Brunswick, New Jersey); Yi Wang (South River, New Jersey)
ABSTRACT	The described invention provides a gel formulation of a composition comprising at least one insecticide in an amount effective to control an insect larval population, an apparatus for autodissmenination of an insecticide for insect management containing (1) a reservoir (2) a transfer plate and cover, and (3) a mesh component, a method and a system for autodissemination for effectively controlling an insect larval population. Also disclosed is an improvided biphasic autodissemination station for control of undesirable insect populations.
FILED	Monday, February 22, 2016
APPL NO	15/050439
ART UNIT	3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/02 (20130101) A01M 1/20 (20130101) A01M 1/2005 (20130101) Original (OR) Class A01M 1/2011 (20130101) A01M 1/2016 (20130101) A01M 2200/011 (20130101) A01M 2200/012 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/00 (20130101) A01N 25/00 (20130101) A01N 25/04 (20130101) A01N 25/04 (20130101) A01N 25/04 (20130101) A01N 25/24 (20130101) A01N 25/24 (20130101) A01N 25/24 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258259 — Multimodal sensory feedback system and method for treatment and assessment of disequilibrium, balance and motion disorders

US 10258259	Zets et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Gary Zets (Maitland, Florida); Bruce Mortimer (Maitland, Florida); Gregory R. Mort (Altamonte Springs, Florida)
ASSIGNEE(S)
INVENTOR(S)	Gary Zets (Maitland, Florida); Bruce Mortimer (Maitland, Florida); Gregory R. Mort (Altamonte Springs, Florida)
ABSTRACT	The invention relates to a system and method for measuring the biomechanical state of a subject using various sensors simultaneously with providing the subject with visual exercises for rehabilitation and assessment of disequilibrium, balance and motion disorders. The biomechanical state of a subject is measured during the subject's performance of a predetermined task. Such measurements are useful for the assessment of disequilibrium, balance and motion disorders and are also useful for the determination of therapeutic application of vibrotactile, auditory, or visual feedback to a subject during the subject's attempt to perform a predetermined task. An intelligent controller compares the subject's biomechanical state to a predetermined parameter to determine a variance. If the variance exceeds a threshold, feedback in the form of visual feedback, vibrotactile feedback or auditory feedback may be provided to the subject as a therapeutic means for enabling the subject to compensate for disorder effects.
FILED	Tuesday, November 29, 2011
APPL NO	13/306872
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/1124 (20130101) Original (OR) Class Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258509 — In-ear noise dosimetry system

US 10258509	Parkins
FUNDED BY	Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Red Tail Hawk Corporation (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Red Tail Hawk Corporation (Philadelphia, Pennsylvania)
INVENTOR(S)	John W. Parkins (Philadelphia, Pennsylvania)
ABSTRACT	An in-ear noise dosimeter in the form of an earplug which senses sound in the ear canal using an eartip which has a sound delivery channel that couples sound at the end closest to the eardrum to an earplug microphone. The earplug can communicate wirelessly with a remote data collection and processing system. A dock unit for storing the earplugs when not worn can compensate for differences in unoccluded-ear versus occluded-ear responses by an acoustic compensator. An electronic compensation filter can be modified by a proximity switch in the earplug which changes state when the earplug is worn in the ear versus stored in a dock unit. The dosimeter can also have a temperature sensor for sensing human body temperature and remotely-located wireless LEDs used to alert the user of high noise dosage. Data can also be downloaded from the earplug using a reader unit.
FILED	Wednesday, April 26, 2017
APPL NO	15/497970
ART UNIT	2654 — Audio Signals
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/12 (20130101) A61B 5/6817 (20130101) A61B 2560/0242 (20130101) A61B 2562/0204 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 11/08 (20130101) Original (OR) Class Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/1016 (20130101) H04R 1/1041 (20130101) H04R 1/1083 (20130101) H04R 2420/07 (20130101) H04R 2460/15 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259804 — Anti-endothelial lipase compounds and methods of using the same in the treatment and/or prevention of cardiovascular diseases

US 10259804	Elshourbagy et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Shifa Biomedical Corporation (Malvern, Pennsylvania)
ASSIGNEE(S)	SHIFA BIOMEDICAL CORPORATION (Malvern, Pennsylvania)
INVENTOR(S)	Nabil Elshourbagy (West Chester, Pennsylvania); Shaker Mousa (Wynantskill, New York); Harold Meyers (Weston, Massachusetts)
ABSTRACT	Endothelial Lipase (EL) inhibitors and methods of using such inhibitors for treating conditions implicating EL are provided herein. The present invention meets the needs in the field by providing small molecule inhibitors of EL function that can be used therapeutically to raise HDL cholesterol levels in blood, and can be used in the prevention and/or treatment of cholesterol and lipoprotein metabolism disorders, including, but not limited to, familial hypercholesterolemia, atherogenic dyslipidemia, atherosclerosis, and, more generally, cardiovascular disease (CVD).
FILED	Wednesday, September 23, 2015
APPL NO	15/514157
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 307/66 (20130101) C07D 405/12 (20130101) Original (OR) Class C07D 405/14 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260466 — Ultrasonic contaminant detection system

US 10260466	Beers et al.
FUNDED BY	Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	David F. Beers (Waipahu, Hawaii); Michael R. Strong (Warrenton, Virginia); John R. Sevick (Nokesville, Virginia); Michael E. Mullen (Lewisberry, Pennsylvania)
ASSIGNEE(S)	Progeny Systems Corporation (Manassas, Virginia)
INVENTOR(S)	David F. Beers (Waipahu, Hawaii); Michael R. Strong (Warrenton, Virginia); John R. Sevick (Nokesville, Virginia); Michael E. Mullen (Lewisberry, Pennsylvania)
ABSTRACT	The invention generally provides a system and method for detecting, measuring, and/or classifying particulate and/or water contaminants in a fluid supply line, storage tank, or sump. Embodiments of the invention provide a contaminant detection apparatus with a detection chamber and a detection module. The detection chamber includes a housing with an internal fluid conduit and one or more acoustic transducers disposed in the housing. Alarms and/or automatic signaling may be included to shut off valves or pumps when contaminants are detected.
FILED	Friday, April 29, 2016
APPL NO	15/142953
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 37/22 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/06 (20130101) G01N 15/10 (20130101) G01N 29/028 (20130101) G01N 29/42 (20130101) G01N 29/221 (20130101) G01N 29/222 (20130101) G01N 29/343 (20130101) G01N 29/345 (20130101) G01N 29/2437 (20130101) G01N 29/4445 (20130101) G01N 33/2847 (20130101) G01N 33/2888 (20130101) G01N 2015/003 (20130101) G01N 2015/0053 (20130101) G01N 2291/02416 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263393 — Vertical-cavity surface-emitting device with epitaxial index guide

US 10263393	Deppe
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida); sdPhotonics, LLC (Oviedo, Florida)
ASSIGNEE(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S)	Dennis G. Deppe (Oviedo, Florida)
ABSTRACT	A semiconductor vertical resonant cavity light source includes an upper and lower mirror that define a vertical resonant cavity. An active region is within the cavity for light generation between the upper and lower mirror. At least one cavity spacer region is between the active region and the upper mirror or lower mirror. The cavity includes an inner mode confinement region and an outer current blocking region. An index guide in the inner mode confinement region is between the cavity spacer region and the upper or lower mirror. The index guide and outer current blocking region each include a lower and upper epitaxial material layer thereon with an epitaxial interface region in between. At least a top surface of the lower material layer includes aluminum in the interface region throughout a full area of an active part of the vertical light source.
FILED	Thursday, February 15, 2018
APPL NO	15/897672
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/183 (20130101) H01S 5/187 (20130101) H01S 5/1833 (20130101) H01S 5/2018 (20130101) H01S 5/2059 (20130101) H01S 5/2072 (20130101) H01S 5/18308 (20130101) H01S 5/18327 (20130101) H01S 5/18333 (20130101) Original (OR) Class H01S 5/18358 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

National Aeronautics and Space Administration (NASA)

10258985 — Formation and control of fluidic species

US 10258985	Link et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Darren Roy Link (Lexington, Massachusetts); David A. Weitz (Bolton, Massachusetts); Manuel Marquez-Sanchez (Lincolnshire, Illinois); Zhengdong Cheng (College Station, Texas)
ABSTRACT	This invention generally relates to systems and methods for the formation and/or control of fluidic species, and articles produced by such systems and methods. In some cases, the invention involves unique fluid channels, systems, controls, and/or restrictions, and combinations thereof. In certain embodiments, the invention allows fluidic streams (which can be continuous or discontinuous, i.e., droplets) to be formed and/or combined, at a variety of scales, including microfluidic scales. In one set of embodiments, a fluidic stream may be produced from a channel, where a cross-sectional dimension of the fluidic stream is smaller than that of the channel, for example, through the use of structural elements, other fluids, and/or applied external fields, etc. In some cases, a Taylor cone may be produced. In another set of embodiments, a fluidic stream may be manipulated in some fashion, for example, to create tubes (which may be hollow or solid), droplets, nested tubes or droplets, arrays of tubes or droplets, meshes of tubes, etc. In some cases, droplets produced using certain embodiments of the invention may be charged or substantially charged, which may allow their further manipulation, for instance, using applied external fields. Non-limiting examples of such manipulations include producing charged droplets, coalescing droplets (especially at the microscale), synchronizing droplet formation, aligning molecules within the droplet, etc. In some cases, the droplets and/or the fluidic streams may include colloids, cells, therapeutic agents, and the like.
FILED	Thursday, March 19, 2015
APPL NO	14/662668
ART UNIT	3752 — Fluid Handling and Dispensing
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 5/0682 (20130101) B01F 13/0062 (20130101) B01F 13/0071 (20130101) B01F 13/0076 (20130101) B01F 2215/0431 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2/04 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 3/502784 (20130101) Original (OR) Class B01L 2200/0673 (20130101) B01L 2300/0867 (20130101) B01L 2400/02 (20130101) B01L 2400/0415 (20130101) B01L 2400/0424 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 5/03 (20130101) B05B 7/061 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10259077 — Modification of surface energy via direct laser ablative surface patterning

US 10259077	Wohl, Jr. et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S)	Christopher J. Wohl, Jr. (Portsmouth, Virginia); Marcus A. Belcher (Sammamish, Washington); John W. Connell (Yorktown, Virginia); John W. Hopkins (Suffolk, Virginia)
ABSTRACT	Surface energy of a substrate is changed without the need for any template, mask, or additional coating medium applied to the substrate. At least one beam of energy directly ablates a substrate surface to form a predefined topographical pattern at the surface. Each beam of energy has a width of approximately 25 micrometers and an energy of approximately 1-500 microJoules. Features in the topographical pattern have a width of approximately 1-500 micrometers and a height of approximately 1.4-100 micrometers.
FILED	Tuesday, March 24, 2015
APPL NO	14/666998
ART UNIT	3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Cleaning in General; Prevention of Fouling in General B08B 17/065 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0006 (20130101) B23K 26/40 (20130101) B23K 26/354 (20151001) B23K 26/355 (20180801) Original (OR) Class B23K 2103/10 (20180801) B23K 2103/14 (20180801) B23K 2103/16 (20180801) B23K 2103/42 (20180801) B23K 2103/50 (20180801) B23K 2103/52 (20180801) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 38/10 (20130101) Optical Elements, Systems, or Apparatus G02B 1/12 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/1064 (20150115) Y10T 428/12993 (20150115) Y10T 428/24355 (20150115) Y10T 428/24479 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

10261263 — Non-line-of-sight optical power transfer system for launching a spacecraft into low earth orbit

US 10261263	Stone et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	Stone Aerospace, Inc. (Del Valle, Texas)
ASSIGNEE(S)	Stone Aerospace, Inc. (Del Valle, Texas)
INVENTOR(S)	William C. Stone (Del Valle, Texas); Bartholomew P. Hogan (Rockville, Maryland)
ABSTRACT	An optical power transfer system for launching a spacecraft into low Earth orbit comprising a ground-based laser power generation station and a launch vehicle optically connected thereto. The generation station is capable of generating high optical power in the range of kilowatts to tens of megawatts and transferring the optical power generated to a launch vehicle to generate thrust. The generation station comprises a high power source, a chilling station, a laser, optical fiber, and at least one coupler. The launch vehicle comprises an actively cooled fiber spooler mounted thereon with a length of fiber for transmission of high optical energy circumscribing at least part thereof. The launch vehicle also contains a working fluid and fluid reservoir, a thruster assembly, an air intake and a storage chamber. In alternative embodiments, the launch vehicle may contain a beam switch assembly, multiple fiber spoolers and multiple thruster assemblies wherein at least one thruster assembly is gimbaled.
FILED	Wednesday, May 27, 2015
APPL NO	14/723138
ART UNIT	2883 — Optics
CURRENT CPC	Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/00 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 41/0085 (20130101) E21B 47/123 (20130101) Optical Elements, Systems, or Apparatus G02B 6/3604 (20130101) Original (OR) Class G02B 6/4268 (20130101) G02B 6/4296 (20130101) G02B 6/4415 (20130101) G02B 6/4436 (20130101) G02B 6/4458 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/30 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 17/00 (20130101) H02J 50/30 (20160201) H02J 50/90 (20160201)
VIEW PATENT	@ USPTO: Full Text PDF

10262951 — Radiation hardened microelectronic chip packaging technology

US 10262951	Kang et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Jin Ho Kang (Newport News, Virginia); Godfrey Sauti (Hampton, Virginia); Cheol Park (Yorktown, Virginia); Luke Gibbons (Williamsburg, Virginia); Sheila Ann Thibeault (Hampton, Virginia); Sharon E. Lowther (Hampton, Virginia); Robert G. Bryant (Williamsburg, Virginia)
ASSIGNEE(S)	National Institute of Aerospace Associates (Hampton, Virginia); The United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S)	Jin Ho Kang (Newport News, Virginia); Godfrey Sauti (Hampton, Virginia); Cheol Park (Yorktown, Virginia); Luke Gibbons (Williamsburg, Virginia); Sheila Ann Thibeault (Hampton, Virginia); Sharon E. Lowther (Hampton, Virginia); Robert G. Bryant (Williamsburg, Virginia)
ABSTRACT	A novel radiation hardened chip package technology protects microelectronic chips and systems in aviation/space or terrestrial devices against high energy radiation. The proposed technology of a radiation hardened chip package using rare earth elements and mulitlayered structure provides protection against radiation bombardment from alpha and beta particles to neutrons and high energy electromagnetic radiation.
FILED	Friday, May 16, 2014
APPL NO	14/279601
ART UNIT	2815 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/78 (20130101) H01L 21/311 (20130101) H01L 23/552 (20130101) H01L 23/556 (20130101) Original (OR) Class H01L 23/3107 (20130101) H01L 23/3128 (20130101) H01L 23/49562 (20130101) H01L 24/73 (20130101) H01L 2224/03831 (20130101) H01L 2224/04042 (20130101) H01L 2224/32225 (20130101) H01L 2224/32225 (20130101) H01L 2224/32225 (20130101) H01L 2224/32245 (20130101) H01L 2224/32245 (20130101) H01L 2224/48091 (20130101) H01L 2224/48227 (20130101) H01L 2224/48227 (20130101) H01L 2224/48227 (20130101) H01L 2224/48247 (20130101) H01L 2224/48247 (20130101) H01L 2224/73265 (20130101) H01L 2224/73265 (20130101) H01L 2224/73265 (20130101) H01L 2224/73265 (20130101) H01L 2224/83192 (20130101) H01L 2924/00 (20130101) H01L 2924/00012 (20130101) H01L 2924/00012 (20130101) H01L 2924/00012 (20130101) H01L 2924/181 (20130101) H01L 2924/181 (20130101) H01L 2924/15311 (20130101) H01L 2924/15311 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263342 — Reflectarray antenna system

US 10263342	Hand et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Goddard Space Flight Center (GSFC)
APPLICANT(S)	Thomas H. Hand (Linthicum Heights, Maryland); Michael E. Cooley (Severna Park, Maryland); David Sall (Owings Mills, Maryland); Gary L. Kempic (Ellicott City, Maryland)
ASSIGNEE(S)	NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S)	Thomas H. Hand (Linthicum Heights, Maryland); Michael E. Cooley (Severna Park, Maryland); David Sall (Owings Mills, Maryland); Gary L. Kempic (Ellicott City, Maryland)
ABSTRACT	One embodiment describes a reflectarray antenna system. The system includes an antenna feed configured to at least one of transmit and receive a wireless signal occupying a frequency band. The system also includes a reflector comprising a reflectarray. The reflectarray includes a plurality of reflectarray elements, where each of the reflectarray elements includes a dipole element. The dipole element of at least a portion of the plurality of reflectarray elements comprises a crossed-dipole portion and a looped-dipole portion. The plurality of reflectarray elements can be configured to selectively phase-delay the wireless signal to provide the wireless signal as a coherent beam.
FILED	Tuesday, October 15, 2013
APPL NO	14/054267
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 3/46 (20130101) H01Q 7/00 (20130101) H01Q 15/14 (20130101) H01Q 19/10 (20130101) H01Q 19/18 (20130101) Original (OR) Class H01Q 21/26 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10263764 — Auto-adaptive digital clock system and method for optimizing data communications

US 10263764	Liaghati et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Marshall Space Flight Center (MSFC)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Amir L. Liaghati (Madison, Alabama); Mahsa L. Liaghati (Madison, Alabama); Chen Jye Chang (Madison, Alabama)
ABSTRACT	A method for optimizing data communications includes receiving a plurality of data and comparing a size of the plurality of data to a preset fixed data packet size. The method also includes transmitting the plurality of data within the preset fixed data packet size in response to the size of the plurality of data corresponding to the preset fixed data packet size. The method additionally include dynamically, autonomously adjusting a clock frequency for formatting data packets to format one or more data packets that accommodate the size of the plurality of data with minimal fill data in response to the size of the plurality of data being different from the preset fixed data packet size. The method further includes formatting the one or more data packets in response to dynamically, autonomously adjusting the clock frequency.
FILED	Tuesday, May 03, 2016
APPL NO	15/145503
ART UNIT	2471 — Multiplex and VoIP
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0006 (20130101) H04L 7/0037 (20130101) Original (OR) Class H04L 67/12 (20130101) Selecting H04Q 9/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Agriculture (USDA)

10258027 — Autodissemination of an insect-growth regulator for insect management

US 10258027	Gaugler et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) Small Business Administration (SBA) Small Business Innovation Research (SBIR) Department of Agriculture (USDA) Agricultural Research Service (ARS)
APPLICANT(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S)	Randy Gaugler (North Brunswick, New Jersey); Devi Suman (New Brunswick, New Jersey); Yi Wang (South River, New Jersey)
ABSTRACT	The described invention provides a gel formulation of a composition comprising at least one insecticide in an amount effective to control an insect larval population, an apparatus for autodissmenination of an insecticide for insect management containing (1) a reservoir (2) a transfer plate and cover, and (3) a mesh component, a method and a system for autodissemination for effectively controlling an insect larval population. Also disclosed is an improvided biphasic autodissemination station for control of undesirable insect populations.
FILED	Monday, February 22, 2016
APPL NO	15/050439
ART UNIT	3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/02 (20130101) A01M 1/20 (20130101) A01M 1/2005 (20130101) Original (OR) Class A01M 1/2011 (20130101) A01M 1/2016 (20130101) A01M 2200/011 (20130101) A01M 2200/012 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/00 (20130101) A01N 25/00 (20130101) A01N 25/04 (20130101) A01N 25/04 (20130101) A01N 25/04 (20130101) A01N 25/24 (20130101) A01N 25/24 (20130101) A01N 25/24 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10258066 — Microwave sterilization or pasteurization transport carriers and system

US 10258066	Tang et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Washington State University (Pullman, Washington)
ASSIGNEE(S)	Washington State University (Pullman, Washington)
INVENTOR(S)	Juming Tang (Pullman, Washington); Fang Liu (Pullman, Washington)
ABSTRACT	The present embodiments are directed to a processing system and transport carrier components for sterilization or pasteurization. In particular, an example embodiment includes a transport carrier for carrying one or more items to be sterilized or pasteurized, wherein the transport carrier includes a carrier base and one or more cross members coupled to and extending between sides of the carrier base. In addition, the transport carrier includes a tray member configured from at least one material of construction selected from a metal, a metal alloy, and a plastic, wherein the tray member extends between ends along the sides of the carrier base, and wherein the tray member further comprises one or more apertures configured to receive the one or more items to be sterilized or pasteurized.
FILED	Monday, July 18, 2016
APPL NO	15/212655
ART UNIT	3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 3/001 (20130101) A23L 3/01 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/12 (20130101) A61L 2/26 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

PP030385 — Strawberry plant named ‘Florida Beauty’

US PP30385	Whitaker et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	Florida Foundation Seed Producers, Inc. (Marianna, Florida); State of Queensland acting through The Department of Agriculture and Fisheries (Brisbane QLD, Australia)
ASSIGNEE(S)	FLORIDA FOUNDATION SEED PRODUCERS, INC. (Marianna, Florida)
INVENTOR(S)	Vance M. Whitaker (Brandon, Florida); Mark Herrington (Nambour, Australia)
ABSTRACT	A new and distinct variety of strawberry plant (Fragaria X ananassa), which originated from seed produced by a hand-pollinated cross between AU 2010-119 and ‘Florida Radiance’. The new strawberry plant, named ‘Florida Beauty’, is distinguished by its compact growth habit; steady yield; fruit that are exceptionally and consistently well-shaped, bright medium-red, and having an exceptional, balanced flavor when grown in west central Florida or other areas that have a subtropical climate similar to that of west central Florida.
FILED	Wednesday, December 07, 2016
APPL NO	15/530158
ART UNIT	1661 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 5/08 (20130101) A01H 6/7409 (20180501) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Department of Commerce (DOC)

10257990 — Growing macroalgae at sea

US 10257990	Goudey
FUNDED BY	Department of Commerce (DOC) National Oceanic and Atmospheric Administration (NOAA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Clifford A. Goudey (Newburyport, Massachusetts)
ASSIGNEE(S)
INVENTOR(S)	Clifford A. Goudey (Newburyport, Massachusetts)
ABSTRACT	The present invention provides a practical and economical means of growing of kelp and other types of macroalgae in large quantities on and in the ocean. Through the use of catenary principles and innovative structural designs, efficient designs emerge that translate into lightweight and low-cost components. The novel design described allows cost-efficient macroalgae farming at scales and at depths unsuitable for present macroalgae farming techniques. The device and methods described present a means of farming these seaweeds for the purpose of providing food, chemical feed stocks, and a biomass suitable for the production of biofuels.
FILED	Friday, December 01, 2017
APPL NO	15/829376
ART UNIT	3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 33/00 (20130101) Original (OR) Class Ships or Other Waterborne Vessels; Equipment for Shipping B63B 35/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10261032 — Noncontact resonameter, process for making and use of same

US 10261032	Orloff et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Center for Nanoscale Science and Technology (CNST)
APPLICANT(S)	NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland); Nathan Daniel Orloff (Houston, Texas); Christian John Long (College Park, Maryland)
ASSIGNEE(S)	NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Washington, District of Columbia)
INVENTOR(S)	Nathan Daniel Orloff (Boulder, Colorado); Christian John Long (Greenbelt, Maryland); Jan Obrzut (Germantown, Maryland)
ABSTRACT	A noncontact resonameter includes: a resonator to: produce an excitation signal including a field; subject a sample to the excitation signal; produce a first resonator signal in a presence of the sample and the excitation signal, the first resonator signal including: a first quality factor of the resonator; a first resonance frequency of the resonator; or a combination thereof, the first resonator signal occurring in an absence of contact between the sample and the resonator; and produce a second resonator signal in a presence of the excitation signal and an absence of the sample, the second resonator signal including: a second quality factor of the resonator; a second resonance frequency of the resonator; or a combination thereof; a circuit in electrical communication with the resonator to receive the first resonator signal and the second resonator signal; and a continuous feeder to: provide the sample proximate to the resonator; dispose the sample intermediately in the field of the excitation signal during production of the first resonator signal; remove the sample from the resonator; and manipulate a position of the sample relative to the resonator in a continuous motion and in an absence of contact between the sample and the resonator.
FILED	Thursday, December 03, 2015
APPL NO	14/958539
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/00 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10261106 — Photonic probe for atomic force microscopy

US 10261106	Aksyuk et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia)
INVENTOR(S)	Vladimir Aksyuk (Gaithersburg, Maryland); Marcelo Davanco (Rockville, Maryland)
ABSTRACT	A photonic probe for atomic force microscopy includes: a cantilever including: a tip; a wing in mechanical communication with the tip; an extension interposed between the tip and the wing to synchronously communicate motion of the tip with the wing; an optical resonator disposed proximate to the cantilever and that: receives input light; and produces output light, such that: the cantilever is spaced by a gap distance from the optical resonator, wherein the gap distance varies as the cantilever moves relative to the optical resonator, and the output light differs from the input light in response to movement of the cantilever relative to the optical resonator; an optical waveguide in optical communication with the optical resonator and that: provides the input light to the optical resonator; and receives the output light from the optical resonator.
FILED	Tuesday, October 31, 2017
APPL NO	15/799337
ART UNIT	2881 — Optics
CURRENT CPC	Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 20/02 (20130101) Original (OR) Class G01Q 20/04 (20130101) G01Q 60/38 (20130101) Optical Elements, Systems, or Apparatus G02B 6/1225 (20130101) G02B 6/29338 (20130101) G02B 2006/12138 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/3026 (20130101) H01J 37/3174 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Transportation (USDOT)

10259923 — Electrically-conductive compositions and methods of using them with pipelines

US 10259923	Phillips
FUNDED BY	Department of Transportation (USDOT) Pipeline and Hazardous Materials Safety Administration (PHMSA)
APPLICANT(S)	Alan D. Phillips (Roanoke, Virginia)
ASSIGNEE(S)	Phillips Intellectual Properties, LLC (Roanoke, Virginia)
INVENTOR(S)	Alan D. Phillips (Roanoke, Virginia)
ABSTRACT	Minimum Federal Safety Standards for corrosion control on buried oil and natural gas pipelines stipulate that metallic pipes should be properly coated and have impressed-current cathodic protection (ICCP) systems in place to control the electrical potential field around susceptible pipes. In certain examples described herein, electrically-conductive nanocomposites can be used and provide intrinsically-safe foam materials without the dielectric shielding issues of existing materials used to physically protect and stabilize buried pipelines. As cured or formed by customary spray applications, the nanocomposite foams described herein are directly compatible with ICCP functionality wherever foam contacts the metallic pipe. Various foam compositions and their use with underground pipelines are described.
FILED	Friday, March 03, 2017
APPL NO	15/449311
ART UNIT	1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) B05D 7/146 (20130101) B05D 7/222 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/14 (20130101) C08G 18/42 (20130101) C08G 18/48 (20130101) C08G 18/0838 (20130101) C08G 18/5021 (20130101) C08G 2150/60 (20130101) C08G 2150/90 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/008 (20130101) Original (OR) Class C08J 9/009 (20130101) C08J 2205/00 (20130101) C08J 2205/05 (20130101) C08J 2205/052 (20130101) C08J 2375/06 (20130101) C08J 2375/08 (20130101) C08J 2375/12 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/042 (20170501) C08K 3/046 (20170501) C08K 9/04 (20130101) C08K 2201/001 (20130101) C08K 2201/005 (20130101) C08K 2201/011 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/24 (20130101) C09D 5/084 (20130101) C09D 7/70 (20180101) C09D 175/06 (20130101) C09D 175/08 (20130101) C09D 175/12 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 13/16 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260061 — Mesoporous catalysts of magnetic nanoparticles and free-radical-producing enzymes, and methods of use

US 10260061	Corgie et al.
FUNDED BY	Department of Transportation (USDOT)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Stephane C. Corgie (Ithaca, New York); Patarawan Kahawong (Nakhonsithammarat, Thailand); Emmanuel P. Giannelis (Ithaca, New York); Larry P. Walker (Ithaca, New York)
ABSTRACT	A composition comprising mesoporous aggregates of magnetic nanoparticles and free-radical producing enzyme (i.e., enzyme-bound mesoporous aggregates), wherein the mesoporous aggregates of magnetic nanoparticles have mesopores in which the free-radical-producing enzyme is embedded. Methods for synthesizing the enzyme-bound mesoporous aggregates are also described. Processes that use said enzyme-bound mesoporous aggregates for depolymerizing lignin, removing aromatic contaminants from water, and polymerizing monomers polymerizable by a free-radical reaction are also described.
FILED	Monday, March 06, 2017
APPL NO	15/450660
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/003 (20130101) B01J 35/0033 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 3/342 (20130101) C02F 2305/08 (20130101) Derivatives of Natural Macromolecular Compounds C08H 6/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/0065 (20130101) C12N 11/14 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/181 (20130101) C12P 2201/00 (20130101) Enzymes C12Y 111/01007 (20130101) C12Y 111/01013 (20130101) C12Y 111/01014 (20130101) C12Y 111/01016 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Veterans Affairs (DVA)

10258529 — Casket transport and lowering device system

US 10258529	Schem
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S)	Clifford Schem (Pleasanton, California)
ABSTRACT	A casket transport and lowering device system is presented. The system includes a transportable frame with extendable rails configured to rotate and extend out over a gravesite. The extendable rails may also include an end rail and one or more extendable feet. The transportable frame may also be protected inside an exterior housing. The system also includes a carriage that rolls along the extendable rails into a position directly over the top of the gravesite. The carriage supports a lowering device upon which the casket rests. When the carriage is positioned over the gravesite, the lowering device is also positioned to lower the casket into the grave.
FILED	Thursday, July 19, 2018
APPL NO	16/040370
ART UNIT	3618 — Audio Signals
CURRENT CPC	Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 19/00 (20130101) Original (OR) Class A61G 21/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10260099 — Compositions and methods for diagnosis and treatment of epilepsy

US 10260099	Delgado-Escueta et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); RIKEN (Saitama, Japan); INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ (Delegacion Tlalpan, Mexico); THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S)	Antonio V. Delgado-Escueta (Malibu, California); Kazuhiro Yamakawa (Saitama, Japan); Toshimitsu Suzuki (Saitama, Japan); Marco Tulio Medina-Hernandez (Tegucigalpa, Honduras); Maria Elisa Alonso Vilatela (Delegacion Coyoacan, Mexico)
ABSTRACT	Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.
FILED	Tuesday, November 24, 2015
APPL NO	14/951407
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) Peptides C07K 16/18 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Homeland Security (DHS)

10262780 — Analytical instrument inductors and methods for manufacturing same

US 10262780	Rosenbaum
FUNDED BY	Department of Homeland Security (DHS) Science and Technology Directorate (DHS-ST)
APPLICANT(S)	FLIR Detection, Inc. (Stillwater, Oklahoma)
ASSIGNEE(S)	FLIR Detection, Inc. (Stillwater, Oklahoma)
INVENTOR(S)	Kevin Rosenbaum (West Lafayette, Indiana)
ABSTRACT	Analytical instrument inductors are provided that can include bundled wired conductive material about a substrate. Analytical instrument inductors are also provided that can include: a tubular substrate defining a plurality of flanges extending outwardly from a core of the substrate wherein opposing flanges define portions of the core; at least one pair of wires wound about a first portion of the core and between at least two flanges, the pair of wires extending to and wound about a second portion of the core; and wherein the one pair of wires are operatively coupled to an analytical instrument to provide inductance. Methods for preparing an instrument inductor are provided. The methods can include bundling wires about and within multiple exterior openings of a hollow-cored substrate; and connecting each of the bundles across the openings.
FILED	Monday, May 11, 2015
APPL NO	14/709205
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 5/02 (20130101) Original (OR) Class H01F 27/402 (20130101) H01F 27/2823 (20130101) H01F 2005/022 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/422 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49073 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

Department of the Treasury (TREASURY)

10260095 — Systems and methods for genetic and biological analysis

US 10260095	Esfandyarpour et al.
FUNDED BY	Department of Health and Human Services (HHS) Department of the Treasury (TREASURY) Internal Revenue Service (IRS)
APPLICANT(S)	GenapSys, Inc. (Redwood City, California)
ASSIGNEE(S)	GENAPSYS, INC. (Redwood City, California)
INVENTOR(S)	Hesaam Esfandyarpour (Redwood City, California); Kosar Baghbani Parizi (Redwood City, California); Mark F. Oldham (Emerald Hills, California); Eric S. Nordman (Palo Alto, California); Richard T. Reel (Hayward, California); Susanne Baumhueter (Redwood City, California); Cheryl Heiner (La Honda, California); Frank Lee (Irvine, California)
ABSTRACT	The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.
FILED	Wednesday, June 13, 2018
APPL NO	16/007829
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 2527/119 (20130101) C12Q 2527/119 (20130101) C12Q 2549/126 (20130101) C12Q 2563/116 (20130101) C12Q 2563/116 (20130101) C12Q 2565/607 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/327 (20130101) G01N 33/5438 (20130101) G01N 33/54313 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

National Security Agency (NSA)

10261561 — Mitigation of on-chip supply voltage based on local and non-local (neighboring) cores' supply voltage information and decision

US 10261561	Chuang et al.
FUNDED BY	National Security Agency (NSA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Pierce I. Chuang (Briarcliff Manor, New York); Phillip J. Restle (Katonah, New York); Christos Vezyrtzis (Elmsford, New York)
ABSTRACT	A voltage droop mitigation system, that includes a first processor core that executes computer executable components stored in a memory. A time-based sensor component generates digital data representing voltage values associated with a power supply. A filtering component digitally conditions the generated digital data, and an analysis component analyzes the conditioned data and determines slope of the power supply voltage and employs counters to determine rate of data change over time; and if the slope is negative and exceeds a first pre-determined value for a pre-determined time period. The system implements one or more voltage droop-reduction techniques at the first processor core; and the first processor core transmits at least one of the following types of information: its voltage value, slope information or decision to apply droop reduction to one or more other cores.
FILED	Tuesday, September 06, 2016
APPL NO	15/257078
ART UNIT	2187 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 1/26 (20130101) G06F 1/305 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

U.S. State Government

10258262 — Sweat sensing device communication security and compliance

US 10258262	Heikenfeld et al.
FUNDED BY	U.S. State Government State of Ohio
APPLICANT(S)	Eccrine Systems, Inc. (Cincinnati, Ohio)
ASSIGNEE(S)	University of Cincinnati, A University of the State of Ohio (Cincinnati, Ohio)
INVENTOR(S)	Jason Heikenfeld (Cincinnati, Ohio); Daniel P. Rose (Cincinnati, Ohio); Ian Papautsky (Willowbrook, Illinois); Wenjing Kang (Malden, Massachusetts); Xiao Wang (Malden, Massachusetts); Michael Ratterman (South Lebanon, Ohio)
ABSTRACT	The invention addresses confounding difficulties involving continuous sweat analyte measurement. Specifically, the present invention provides: at least one component capable of monitoring whether a sweat sensing device is in sufficient contact with a wearer's skin to allow proper device operation; at least one component capable of monitoring whether the device is operating on a wearer's skin; at least one means of determining whether the device wearer is a target individual within a probability range; at least one component capable of generating and communicating alert messages to the device user(s) related to: wearer safety, wearer physiological condition, compliance with a requirement to wear a device, device operation; compliance with a behavior requirement, or other purposes that may be derived from sweat sensor data; and the ability to utilize aggregated sweat sensor data that may be correlated with information external to the device to enhance the predictive capabilities of the device.
FILED	Monday, November 28, 2016
APPL NO	15/362303
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0002 (20130101) A61B 5/0022 (20130101) A61B 5/024 (20130101) A61B 5/112 (20130101) A61B 5/117 (20130101) A61B 5/0205 (20130101) A61B 5/0531 (20130101) A61B 5/0533 (20130101) A61B 5/742 (20130101) A61B 5/746 (20130101) A61B 5/1477 (20130101) A61B 5/4266 (20130101) A61B 5/4833 (20130101) A61B 5/4845 (20130101) A61B 5/6802 (20130101) A61B 5/6833 (20130101) A61B 5/6843 (20130101) A61B 5/7275 (20130101) A61B 5/7475 (20130101) A61B 5/14517 (20130101) Original (OR) Class A61B 5/14521 (20130101) A61B 5/14546 (20130101) A61B 5/14551 (20130101) A61B 2560/0252 (20130101) A61B 2562/08 (20130101) A61B 2562/125 (20130101) A61B 2562/164 (20130101) A61B 2562/0214 (20130101) A61B 2562/0219 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/30 (20130101) B05D 3/007 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/12 (20130101) B32B 2535/00 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00892 (20130101) G06K 2009/00939 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/18 (20130101) Selecting H04Q 9/00 (20130101) H04Q 2209/40 (20130101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) Technical Subjects Covered by Former US Classification Y10T 29/49155 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

10260373 — Flow splitter for a fluid system of a gas turbine engine

US 10260373	Lewis et al.
FUNDED BY
APPLICANT(S)	Rolls-Royce Corporation (Indianapolis, Indiana)
ASSIGNEE(S)	ROLLS-ROYCE CORPORATION (Indianapolis, Indiana)
INVENTOR(S)	Jennifer Ann Lewis (Danville, Indiana); Duane Allen Morris (Indianapolis, Indiana)
ABSTRACT	A gas turbine engine is disclosed having a working fluid system capable of moving a working fluid. The working fluid system includes a flow splitter capable of splitting the working fluid into different streams. In one form the flow splitter member is a T-shape, but other embodiments can take on other shapes. The flow splitter can include an internal scoop used to split the flow. In one form internal scoop is annular in shape and includes a turn to direct a split flow.
FILED	Monday, June 30, 2014
APPL NO	14/319961
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/18 (20130101) Original (OR) Class F01D 25/20 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/14 (20130101) F02C 7/18 (20130101) F02C 7/222 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/20 (20130101) F05D 2260/98 (20130101) F05D 2260/602 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 39/00 (20130101) F16L 41/02 (20130101) F16L 41/021 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/85938 (20150401)
VIEW PATENT	@ USPTO: Full Text PDF

10262727 — Gradiometric flux qubit system

US 10262727	Przybysz et al.
FUNDED BY
APPLICANT(S)	Anthony Joseph Przybysz (Linthicum, Maryland); David George Ferguson (Takoma Park, Maryland)
ASSIGNEE(S)	NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S)	Anthony Joseph Przybysz (Linthicum, Maryland); David George Ferguson (Takoma Park, Maryland)
ABSTRACT	One example includes a flux qubit readout circuit. The circuit includes a gradiometric SQUID that is configured to inductively couple with a gradiometric flux qubit to modify flux associated with the gradiometric superconducting quantum interference device (SQUID) based on a flux state of the flux qubit. The circuit also includes a current source configured to provide a readout current through the gradiometric SQUID during a state readout operation to determine the flux state of the gradiometric flux qubit at a readout node.
FILED	Monday, July 10, 2017
APPL NO	15/645736
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 1/28 (20130101) G01R 19/0084 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 11/44 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, April 16, 2019.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190416.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital