FedInvent™ Patents
Patent Details for Tuesday, April 23, 2019
This page was updated on Monday, March 27, 2023 at 05:47 AM GMT
Department of Health and Human Services (HHS)
| US 10264974 | Hong et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Guosong Hong (Stanford, California); Jerry Chung-yu Lee (San Diego, California); Ngan Fong Huang (Mountain View, California); John P. Cooke (Stanford, California); Hongjie Dai (Cupertino, California) |
| ABSTRACT | Disclosed are methods for imaging lumen-forming structures such as blood vessels using near-infrared fluorescence in the NIR-II region of 1000-1700 nm. The fluorescence is created by excitation of solubilized nano-structures that are delivered to the structures, such as carbon nanotubes, quantum dots or organic molecular fluorophores attached to hydrophilic polymers. These nanostructures fluoresce in the NIR-II region when illuminated through the skin and tissues. Fine anatomical vessel resolution down to −30 μm and high temporal resolution up to 5-10 frames per second is obtained for small-vessel imaging with up to 1 cm penetration depth in mouse hind limb, which compares favorably to tomographic imaging modalities such as CT and MRI with much higher spatial and temporal resolution, and compares favorably to scanning microscopic imaging techniques with much deeper penetration. |
| FILED | Tuesday, November 20, 2012 |
| APPL NO | 14/443899 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/0071 (20130101) Original (OR) Class A61B 5/0075 (20130101) A61B 5/0086 (20130101) A61B 5/0261 (20130101) A61B 5/0275 (20130101) A61B 5/4887 (20130101) A61B 5/7278 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0019 (20130101) A61K 49/0041 (20130101) A61K 49/0054 (20130101) A61K 49/0093 (20130101) A61K 49/0095 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6456 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10264976 | Pang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yi Pang (Copley, Ohio); Bin Liu (Akron, Ohio) |
| ASSIGNEE(S) | The University of Akron (Akron, None) |
| INVENTOR(S) | Yi Pang (Copley, Ohio); Bin Liu (Akron, Ohio) |
| ABSTRACT | Flavonoid compounds may be prepared that are selective for certain cell organelles, and may be used as biological imaging agents. Organelles that may be imaged with flavonoid compounds include mitochondria and lysosomes. Advantageously, the flavonoids show specificity to certain organelles and may exhibit a florescence “turn-on” mechanism, where the flavonoids that have target an organelle exhibit a florescence response when excited. |
| FILED | Friday, November 06, 2015 |
| APPL NO | 14/934665 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 49/0021 (20130101) Heterocyclic Compounds C07D 311/30 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6533 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1135 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/322 (20130101) C12N 2310/322 (20130101) C12N 2310/344 (20130101) C12N 2310/531 (20130101) C12N 2310/3515 (20130101) C12N 2310/3521 (20130101) C12N 2310/3531 (20130101) C12N 2310/3533 (20130101) C12N 2320/30 (20130101) C12N 2320/32 (20130101) C12N 2320/35 (20130101) C12N 2320/53 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10264990 | Pasley et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Brian Pasley (Berkeley, California); Robert T. Knight (El Cerrito, California) |
| ABSTRACT | The present disclosure provides methods of decoding speech from brain activity data. Aspects of the methods include receiving brain speech activity data from a subject, and processing the brain speech activity data to output speech feature data. Also provided are devices and systems for practicing the subject methods. |
| FILED | Friday, October 25, 2013 |
| APPL NO | 14/438496 |
| ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/048 (20130101) A61B 5/0476 (20130101) A61B 5/0478 (20130101) A61B 5/741 (20130101) A61B 5/742 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/4803 (20130101) A61B 5/4836 (20130101) A61B 5/04845 (20130101) A61B 5/6814 (20130101) A61B 5/6868 (20130101) A61B 5/6898 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10264994 | Spottiswoode et al. |
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| FUNDED BY |
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| APPLICANT(S) | Siemens Healthcare Gmbh (Erlangen OT, Germany); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | Siemens Healthcare GmbH (Erlangen, Germany); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Bruce S. Spottiswoode (Chicago, Illinois); Peter Kellman (Bethesda, Maryland) |
| ABSTRACT | A method for performing free breathing pixel-wise myocardial T1 parameter mapping includes performing a free-breathing scan of a cardiac region at a plurality of varying saturation recovery times to acquire a k-space dataset; generating an image dataset based on the k-space dataset; and performing a respiratory motion correction process on the image dataset. The respiratory motion correction process comprises selecting a target image from the image dataset, co-registering each image in the image dataset to the target image to determine a spatial alignment measurement for each image, and identifying a subset of the image dataset comprising images with the spatial alignment measurement above a predetermined value. Following the respiratory motion correction process, a pixel-wise fitting is performed on the image dataset to estimate T1 relaxation time values for the cardiac region. Then, a pixel-map of the cardiac region is produced depicting the T1 relaxation time values. |
| FILED | Monday, May 16, 2016 |
| APPL NO | 15/155205 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0044 (20130101) A61B 5/055 (20130101) Original (OR) Class A61B 5/0816 (20130101) A61B 5/7214 (20130101) A61B 5/14535 (20130101) A61B 2576/023 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/5602 (20130101) G01R 33/5608 (20130101) G01R 33/5673 (20130101) G01R 33/56509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265029 | Sarrafzadeh et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Majid Sarrafzadeh (Anaheim, California); Myung-Kyung Suh (Los Angeles, California); Mars Lan (Los Angeles, California); Hassan Ghasemzadeh (Los Angeles, California) |
| ABSTRACT | Systems and methods for generalized precursor pattern discovery that work with a wide range of biomedical signals and applications to detect a wide range of medical events are disclosed. In some embodiments, the methods and systems do not require domain-specific knowledge or significant reconfiguration based on the medical event being analyzed, hence it is also possible to discover patterns previously unknown to experts. In some embodiments, to build precursor pattern detection models, the system obtains annotated monitoring data. Positive and negative segments are extracted from the annotated monitoring data, and are preprocessed. Features are extracted from the preprocessed segments, and selected features are chosen from the extracted features. The selected features are classified to create the precursor pattern detection model The precursor pattern detection model may then be used in real time to detect occurrences of the medical event of interest. |
| FILED | Wednesday, August 28, 2013 |
| APPL NO | 14/424946 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/112 (20130101) A61B 5/0402 (20130101) A61B 5/0476 (20130101) A61B 5/725 (20130101) A61B 5/726 (20130101) A61B 5/746 (20130101) A61B 5/02055 (20130101) A61B 5/4094 (20130101) A61B 5/4818 (20130101) A61B 5/7264 (20130101) A61B 5/7282 (20130101) Original (OR) Class Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps F04C 2270/041 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265155 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Helen H. Lu (New York, New York); Jeffrey Spalazzi (Staten Island, New York); Kristen L. Moffat (Oakmont, Pennsylvania); William N. Levine (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Helen H. Lu (New York, New York); Jeffrey Spalazzi (Staten Island, New York); Kristen L. Moffat (Oakmont, Pennsylvania); William N. Levine (New York, New York) |
| ABSTRACT | An implantable device is provided for soft-tissue or soft tissue-to-bone repair, fixation, augmentation, or replacement that includes a biomimetic and biodegradable nanofiber scaffold. Also provided is a fully synthetic implantable multiphased scaffold which includes, in a single continuous construct, a plurality of phases to mimic the natural anatomy of a tendon or ligament and their insertion sites. Also provided are scaffold apparatuses for musculoskeletal tissue engineering. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 14/503053 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/08 (20130101) Original (OR) Class A61F 2/0811 (20130101) A61F 2002/0858 (20130101) A61F 2210/0004 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/32 (20130101) A61K 35/32 (20130101) A61K 38/18 (20130101) A61K 38/18 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 2430/34 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265258 | Christiano et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Angela M. Christiano (Mahwah, New Jersey); Raphael Clynes (West Nyack, New York) |
| ABSTRACT | The invention provides for methods for treating a hair loss disorder in a subject by administering a Janus Kinase/Signal Transducers and Activators of Transcription inhibitor. |
| FILED | Friday, August 04, 2017 |
| APPL NO | 15/668814 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/41 (20130101) A61K 8/64 (20130101) A61K 8/4953 (20130101) Original (OR) Class A61K 31/52 (20130101) A61K 31/63 (20130101) A61K 31/137 (20130101) A61K 31/277 (20130101) A61K 31/407 (20130101) A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/529 (20130101) A61K 31/553 (20130101) A61K 31/713 (20130101) A61K 31/5377 (20130101) A61K 31/7052 (20130101) A61K 2800/782 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265275 | Messersmith et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Phillip B. Messersmith (Clarendon Hills, Illinois); Tadas S. Sileika (Northbrook, Illinois); Ran Zhang (Evanston, Illinois); Devin G. Barrett (Evanston, Illinois) |
| ABSTRACT | A method of making a facile, surface-independent, polyphenol coating is disclosed. In general, the method includes contacting at least a portion of the substrate to be coated with an aqueous solution containing one or more salts and one or more nitrogen-free phenolic compounds. Substrates of all kinds may be used, and compounds used to make the coating may include epigallocatechin-3-gallate (EGCG), epigallocatechin (EGC) and epicatechin-3-gallate (ECG), tannic acid, gallic acid, pyrogallol, and/or other nitrogen-free phenolic compounds. The coating made using the method, methods of using the coating, and kits comprising the coating precursors are also disclosed. |
| FILED | Monday, February 24, 2014 |
| APPL NO | 14/187741 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 31/16 (20130101) A01N 43/16 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) Original (OR) Class A61K 31/192 (20130101) A61K 31/353 (20130101) A61K 31/7028 (20130101) A61K 31/7034 (20130101) A61K 36/00 (20130101) Separation B01D 15/08 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/285 (20130101) C02F 1/288 (20130101) C02F 2101/20 (20130101) C02F 2101/22 (20130101) C02F 2305/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/44 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/065 (20130101) C08J 2369/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 4/00 (20130101) C09D 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265288 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kun Ping Lu (Newton, Massachusetts); Shuo Wei (Chestnut Hill, Massachusetts); Xiao Zhen Zhou (Newton, Massachusetts) |
| ABSTRACT | The invention features methods of treating a proliferative disorder characterized by elevated Pin1 marker levels and/or reduced Pin1 Ser71 phosphorylation in a subject by administering a retinoic acid compound. Additionally, the invention features methods of treating proliferative disorders (e.g., proliferative disorders characterized by elevated Pin1 marker levels) by administering a retinoic acid compound in combination with another anti-proliferative compound. Finally, the invention also features methods including high-throughput screens for discovering and validating Pin1 inhibitors. |
| FILED | Thursday, July 17, 2014 |
| APPL NO | 14/334052 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/11 (20130101) A61K 31/11 (20130101) A61K 31/203 (20130101) Original (OR) Class A61K 31/203 (20130101) A61K 31/232 (20130101) A61K 31/232 (20130101) A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 31/475 (20130101) A61K 31/475 (20130101) A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 31/4418 (20130101) A61K 31/4418 (20130101) A61K 31/7064 (20130101) A61K 31/7064 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265313 | Desai |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Sanjay A. Desai (Potomac, Maryland) |
| ABSTRACT | The invention provides methods of treating or preventing malaria comprising administering to an animal an effective amount of a compound of formula I: Q-Y—R1—R2 (I), wherein Q, Y, R1, and R2 are as described herein. Methods of inhibiting a plasmodial surface anion channel of a parasite in an animal are also provided. The invention also provides pharmaceutical compositions comprising a compound represented by formula I in combination with any one or more compounds represented by formulas II, V, and VI. Use of the pharmaceutical compositions for treating or preventing malaria or for inhibiting a plasmodial surface anion channel in animals including humans are also provided. Also provided by the invention are clag3 amino acid sequences and related nucleic acids, vectors, host cells, populations of cells, antibodies, and pharmaceutical compositions. |
| FILED | Tuesday, October 03, 2017 |
| APPL NO | 15/723677 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/50 (20130101) A61K 31/422 (20130101) A61K 31/423 (20130101) A61K 31/427 (20130101) A61K 31/433 (20130101) A61K 31/433 (20130101) A61K 31/437 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) A61K 31/498 (20130101) A61K 31/501 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/554 (20130101) A61K 31/554 (20130101) A61K 31/4355 (20130101) A61K 31/4439 (20130101) A61K 31/4741 (20130101) A61K 39/015 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 239/84 (20130101) C07D 241/44 (20130101) C07D 263/57 (20130101) C07D 277/54 (20130101) C07D 281/16 (20130101) C07D 409/04 (20130101) C07D 409/14 (20130101) C07D 413/14 (20130101) C07D 417/06 (20130101) C07D 491/048 (20130101) C07D 498/04 (20130101) C07D 513/04 (20130101) Peptides C07K 14/445 (20130101) C07K 16/205 (20130101) C07K 2319/21 (20130101) C07K 2319/43 (20130101) Technologies for Adaptation to Climate Change Y02A 50/411 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265315 | O'Malley et al. |
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| FUNDED BY |
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| APPLICANT(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| ASSIGNEE(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | Bert W. O'Malley (Houston, Texas); David Michael Lonard (Pearland, Texas); Jin Wang (Sugar Land, Texas); Jianming Xu (Bellaire, Texas); Jianwei Chen (Houston, Texas) |
| ABSTRACT | Small molecule regulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing SRC-related diseases. The SRC-related diseases can include cancer, metabolic disorders, human immunodeficiency virus, neurodegenerative disorders, and/or inflammatory diseases. Also provided are methods for regulating SRC family proteins in a cell. |
| FILED | Thursday, April 06, 2017 |
| APPL NO | 15/480731 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4402 (20130101) Heterocyclic Compounds C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 409/12 (20130101) C07D 413/12 (20130101) C07D 417/12 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 498/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265320 | Schmidt et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ann Marie Schmidt (Franklin Lakes, New Jersey); Ravichandran Ramasamy (Ardsley, New York); Alexander Shekhtman (Glenmont, New York); Vivek Rai (Allahabad, India); Michaele B. Manigrasso (New York, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York); New York Universirty (New York, New York) |
| INVENTOR(S) | Ann Marie Schmidt (Franklin Lakes, New Jersey); Ravichandran Ramasamy (Ardsley, New York); Alexander Shekhtman (Glenmont, New York); Vivek Rai (Allahabad, India); Michaele B. Manigrasso (New York, New York) |
| ABSTRACT | Amino, amido, and heterocyclic compounds are disclosed. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, diabetes complications, inflammation, and neurodegeneration, obesity, cancer, ischemia/reperfusion injury, cardiovascular disease and other diseases related to RAGE activity. |
| FILED | Wednesday, May 25, 2016 |
| APPL NO | 15/164324 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/47 (20130101) A61K 31/52 (20130101) A61K 31/137 (20130101) A61K 31/167 (20130101) A61K 31/185 (20130101) A61K 31/353 (20130101) A61K 31/357 (20130101) A61K 31/403 (20130101) A61K 31/426 (20130101) A61K 31/427 (20130101) A61K 31/454 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/4045 (20130101) A61K 31/4184 (20130101) A61K 31/4439 (20130101) A61K 31/4985 (20130101) A61K 31/5377 (20130101) Original (OR) Class Heterocyclic Compounds C07D 213/75 (20130101) C07D 239/42 (20130101) C07D 277/28 (20130101) C07D 319/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265329 | Sharifi et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Nima Sharifi (Cleveland, Ohio); Zhenfei Li (Cleveland, Ohio); Richard Auchus (Cleveland, Ohio) |
| ABSTRACT | A method of treating steroid-dependent disease such as prostate cancer in a subject is described that includes administering a therapeutically effective amount a CYP17A inhibitor and an effective amount of a 5-α-reductase inhibitor to the subject. |
| FILED | Monday, March 07, 2016 |
| APPL NO | 15/062740 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/58 (20130101) Original (OR) Class A61K 31/58 (20130101) A61K 31/473 (20130101) A61K 31/473 (20130101) A61K 31/4166 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265338 | Korinek et al. |
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| FUNDED BY |
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| APPLICANT(S) | Astrocyte Pharmaceuticals, Inc. (Cambridge, Massachusetts); The Board of Regents of the University of Texas System (San Antonio, Texas) |
| ASSIGNEE(S) | ASTROCYTE PHARMACEUTICALS, INC. (Cambridge, Massachusetts); THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMS (Austin, Texas) |
| INVENTOR(S) | William S. Korinek (Mystic, Connecticut); James D. Lechleiter (San Antonio, Texas); Theodore E. Liston (Stonington, Connecticut) |
| ABSTRACT | The present invention relates to compounds and methods of use thereof for treatment of certain disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries. |
| FILED | Monday, August 07, 2017 |
| APPL NO | 15/670738 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7076 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265349 | Chatila et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Talal A. Chatila (Belmont, Massachusetts); Lynn Bry (Jamaica Plain, Massachusetts); Georg Gerber (Boston, Massachusetts); Azza Abdel-Gadir (Boston, Massachusetts); Rima Rachid (Belmont, Massachusetts) |
| ABSTRACT | Disclosed are methods and compositions for the prevention and treatment of food allergy. In particular, described herein are microbial consortia, including minimal microbial consortia, that can prevent and/or cure food allergy. In certain embodiments, the consortia comprise certain members of the taxa Clostridiales and/or Bacteroidetes. |
| FILED | Thursday, November 02, 2017 |
| APPL NO | 15/801783 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/0053 (20130101) A61K 35/74 (20130101) A61K 35/741 (20130101) A61K 35/742 (20130101) Original (OR) Class A61K 35/744 (20130101) A61K 35/745 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/08 (20180101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265372 | Conboy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Irina M. Conboy (El Sobrante, California); David Vernon Schaffer (Danville, California); Hanadie Yousef (San Mateo, California); Michael J. Conboy (El Sobrante, California); Wendy Cousin (Berkeley, California); Christian Elabd (Berkeley, California) |
| ABSTRACT | Methods, pharmaceutical compositions, and kits are provided for treating a subject with an effective amount of an oxytocin receptor (OXTR) agonist and an effective amount of an ALK5 antagonist. In certain aspects, the OXTR agonist may be oxytocin or an oxytocin analog (e.g., a small molecule). The ALK 5 antagonist may be a small molecule, such as 2-(3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine, LY2157299, A 83-01, D 4476, GW 788388, LY 364947, Rep Sox, SB 431542, SB 505124, SB 525334, or SD 208. In certain aspects, the amounts of the OXTR agonist and ALK5 antagonist may be sufficient to induce muscle regeneration and/or neural cell regeneration in the subject. |
| FILED | Wednesday, August 12, 2015 |
| APPL NO | 15/327309 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/444 (20130101) A61K 31/536 (20130101) A61K 38/11 (20130101) Original (OR) Class A61K 38/1841 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0623 (20130101) C12N 5/0658 (20130101) C12N 2501/30 (20130101) C12N 2501/727 (20130101) C12N 2501/999 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265378 | Gudas et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Lorraine J Gudas (New York, New York); Xiao-Han Tang (Staten Island, New York); Kwame Osei-Sarfo (Astoria, New York); Alison Urvalek (Astoria, New York) |
| ABSTRACT | This invention relates to pharmaceutical composition and methods of using RXR agonist and/or RAR agonist for the treatment or prevention of head and neck cancer. |
| FILED | Monday, March 09, 2015 |
| APPL NO | 15/125081 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/44 (20130101) A61K 31/44 (20130101) A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 31/203 (20130101) A61K 31/203 (20130101) A61K 38/177 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265382 | Felber et al. |
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| FUNDED BY |
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| APPLICANT(S) | NOVARTIS AG (Basel, Switzerland); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | NOVARTIS AG (Basel, Switzerland); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Barbara K. Felber (Rockville, Maryland); Sergio Finkielsztein (Newton, Massachusetts); George N. Pavlakis (Bethesda, Maryland); John V. Vournakis (Charleston, South Carolina) |
| ABSTRACT | The present invention relates to agents that modulate interleυkin-15 (“IL-15”) signal transduction or function (“Therapeutic Agents”) and the use ol” those agents to modulate immune function. The Therapeutic Agents target the interaction between IL-15 and its receptor and modulate IL-15-induced signal transduction. The Therapeutic Agents may be formulated with polymers, such as poly-β-1-♦4-N-acetylglucosamine. for administration to a human subject to modulate IL-15-mediated immune function. |
| FILED | Friday, February 03, 2017 |
| APPL NO | 15/424621 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/13 (20130101) A61K 38/1793 (20130101) A61K 38/2086 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 47/36 (20130101) A61K 2039/5152 (20130101) A61K 2039/5156 (20130101) A61K 2039/55527 (20130101) Peptides C07K 16/244 (20130101) C07K 16/2866 (20130101) C07K 2317/24 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0686 (20130101) C12N 15/85 (20130101) C12N 2500/90 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265383 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (Manhasset, New York) |
| ASSIGNEE(S) | The Feinstein Institute For Medical Research (Manhasset, New York) |
| INVENTOR(S) | Ping Wang (Roslyn, New York); Weng-Lang Yang (Leonia, New Jersey) |
| ABSTRACT | Methods are disclosed for mitigating radiation injury to a subject by administration of ghrelin. |
| FILED | Tuesday, September 08, 2015 |
| APPL NO | 15/508958 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/22 (20130101) Original (OR) Class A61K 38/25 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2005/1094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265394 | Kornbluth et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard Syd Kornbluth (La Jolla, California); Geoffrey William Stone (Coral Gables, Florida) |
| ABSTRACT | The present invention is drawn to compositions and methods to enhance an immune response in order to prevent or treat infections or hyperproliferative diseases such as cancer. More particularly, the composition is an immunostimulatory intracellular signaling peptide fused directly or indirectly to a peptide that leads to multimerization into complexes of three or more units, where the intracellular signaling peptide must be present in a complex of three or more units in order to stimulate an immune response. Inserting this fusion construct into viruses like HIV-1 or introducing it into dendritic cells or tumor cells is predicted to lead to a positive therapeutic effect in humans, non-human mammals, birds, and fish. |
| FILED | Thursday, March 16, 2017 |
| APPL NO | 15/461336 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/763 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/5256 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/005 (20130101) C07K 14/70578 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/16222 (20130101) C12N 2710/16632 (20130101) C12N 2710/24143 (20130101) C12N 2740/15011 (20130101) C12N 2740/16011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265405 | Peppas et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Nicholas A. Peppas (Austin, Texas); Sarena D. Horava (Austin, Texas) |
| ABSTRACT | In some aspects, a composition comprising a pH-sensitive crosslinked copolymer of methacrylic acid and poly(ethylene glycol) monomethyl ether methacrylate and a therapeutic protein is provided. In some embodiments, the therapeutic protein is a high molecular weight protein such as factor VIII or factor IX. In some embodiments, the composition is orally administered to a patient to treat a disease or disorder such as, e.g., hemophilia. |
| FILED | Tuesday, November 17, 2015 |
| APPL NO | 14/944173 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 38/4846 (20130101) A61K 47/58 (20170801) A61K 47/60 (20170801) A61K 47/6903 (20170801) A61K 47/48176 (20130101) Original (OR) Class Enzymes C12Y 304/21022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265413 | Ofner, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF THE SCIENCES IN PHILADELPHIA (Pennsylvania, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF THE SCIENCES IN PHILADELPHIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Clyde M. Ofner, III (Philadelphia, Pennsylvania); Chris Cammarata (Philadelphia, Pennsylvania); Brian Rhodes (Philadelphia, Pennsylvania); Darren Wu (Philadelphia, Pennsylvania) |
| ABSTRACT | Disclosed herein are high molecular weight compounds comprising gelatin and doxorubicin, where the gelatin is covalently linked to doxorubicin through a cleavable linker. The cleavable linker can be cleaved under appropriate physiological conditions, and thus lead to the freeing of doxorubicin. The free doxorubicin can then exert its cytotoxic effects on cancer cells. Disclosed herein are methods of making the high molecular weight gelatin-doxorubicin conjugates and methods of use of the same. |
| FILED | Friday, October 30, 2015 |
| APPL NO | 15/524931 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 47/64 (20170801) A61K 47/65 (20170801) A61K 47/6435 (20170801) Original (OR) Class A61K 47/6903 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265414 | Govindan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Serengulam V. Govindan (Summit, New Jersey); Sung-Ju Moon (New Providence, New Jersey); David M. Goldenberg (Mendham, New Jersey) |
| ABSTRACT | The present invention relates to therapeutic conjugates with improved ability to target various diseased cells containing a targeting moiety (such as an antibody or antibody fragment), a linker and a therapeutic moiety, and further relates to processes for making and using the conjugates. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/045400 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) A61K 45/06 (20130101) A61K 47/6803 (20170801) Original (OR) Class A61K 47/6841 (20170801) A61K 47/6849 (20170801) A61K 47/6851 (20170801) A61K 47/6853 (20170801) A61K 47/6855 (20170801) A61K 47/6857 (20170801) A61K 47/6861 (20170801) A61K 47/6889 (20170801) A61K 2039/505 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Heterocyclic Compounds C07D 491/22 (20130101) Peptides C07K 16/18 (20130101) C07K 16/30 (20130101) C07K 16/303 (20130101) C07K 16/1063 (20130101) C07K 16/2803 (20130101) C07K 16/2833 (20130101) C07K 16/2863 (20130101) C07K 16/2887 (20130101) C07K 16/3046 (20130101) C07K 16/3076 (20130101) C07K 16/3092 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/40 (20130101) C07K 2317/52 (20130101) C07K 2317/53 (20130101) C07K 2317/94 (20130101) Technologies for Adaptation to Climate Change Y02A 50/394 (20180101) Y02A 50/401 (20180101) Y02A 50/403 (20180101) Y02A 50/412 (20180101) Y02A 50/473 (20180101) Y02A 50/478 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265417 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | James M. Wilson (Glen Mills, Pennsylvania); Guangping Gao (Westborough, Massachusetts); Mauricio R. Alvira (Philadelphia, Pennsylvania); Luc H. Vandenberghe (Weston, Massachusetts) |
| ABSTRACT | Sequences of novel adeno-associated virus capsids and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. AAV-mediated delivery of therapeutic and immunogenic genes using the vectors of the invention is also provided. |
| FILED | Wednesday, August 03, 2016 |
| APPL NO | 15/227418 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Original (OR) Class Peptides C07K 14/005 (20130101) C07K 14/705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/644 (20130101) C12N 15/86 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14142 (20130101) C12N 2750/14143 (20130101) C12N 2750/14151 (20130101) C12N 2830/008 (20130101) C12N 2830/48 (20130101) C12N 2830/85 (20130101) Enzymes C12Y 304/21022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265458 | Young et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advent Access Pte. Ltd. (Singapore, Singapore) |
| ASSIGNEE(S) | ADVENT ACCESS PTE. LTD. (Singapore, Singapore) |
| INVENTOR(S) | Nathaniel P. Young (Salt Lake City, Utah); Mark A. Crawford (Sandy, Utah) |
| ABSTRACT | A vascular access port can include a base that can be attached to a vessel and a body extending away from the base in at least a vertical direction. A height of the body in the vertical direction can be sufficiently small such that the entire port can be implanted subcutaneously in a patient. The port can include a guidance passageway that is at least partially defined by the body and can direct an access device into a vessel of a patient when the port is attached to the vessel. In some arrangements, the guidance passageway includes a funnel region that decreases in size from a proximal end of the guidance passageway toward a distal end of the guidance passageway that defines an opening through the bottom surface of the port. |
| FILED | Monday, November 09, 2015 |
| APPL NO | 14/936567 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0057 (20130101) A61B 17/3423 (20130101) A61B 2017/3425 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3653 (20130101) A61M 1/3659 (20140204) A61M 1/3661 (20140204) Original (OR) Class A61M 39/0208 (20130101) A61M 2205/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265497 | Tsai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Li-Huei Tsai (Cambridge, Massachusetts); Emery Brown (Brookline, Massachusetts); Hannah Iaccarino (Somerville, Massachusetts); Anthony James Martorell (Cambridge, Massachusetts); Chinnakkaruppan Adaikkan (Somerville, Massachusetts) |
| ABSTRACT | The present disclosure provides systems and methods for at least one of preventing, reducing, and treating a level of or change in at least one of amyloid-β (Aβ) peptide, C-terminal fragment-β (β-CTF), β-secretase (BACE1), γ-secretase, neuroinflammation, and/or dementia (e.g., Alzheimer's disease or age-related decline) in a subject by inducing synchronized gamma oscillations in the brain of the subject using, for example, a stimulus-emitting device to emit a stimulus (e.g., light, sound, and/or haptic) at a frequency (e.g., about 40 Hz) that synchronously activates in vivo a specific cell type (e.g., fast-spiking-parvalbumin (FS-PV) immunoreactive interneurons) and/or brain region (e.g., a sensory cortex and/or hippocampus) of the subject. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/360637 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/00 (20130101) Original (OR) Class A61M 2021/0022 (20130101) A61M 2021/0027 (20130101) A61M 2021/0044 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0622 (20130101) A61N 2005/063 (20130101) A61N 2005/0651 (20130101) A61N 2005/0662 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265511 | McAllister et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Devin McAllister (Marietta, Georgia); Mark Prausnitz (Atlanta, Georgia); Sabastien Henry (Smyrna, Georgia); James J. Norman (North Bethesda, Maryland) |
| ABSTRACT | Embodiments of the present application provide microneedle patches and systems, and methods for use of such patches and systems. In one aspect, a microneedle patch is provided including a tab portion for handling the microneedle patch. In another aspect, a system is provided including a microneedle patch and a tray for housing the microneedle patch. In still another aspect, various indicators providing for providing feedback prior to, during, and after administration of the microneedle patch are provided. Advantageously, the described microneedle patches and systems provide improved handling and ease of application of the microneedle patches to skin for the delivery of therapeutic agents. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 15/025683 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0023 (20130101) A61M 2037/0046 (20130101) A61M 2037/0061 (20130101) A61M 2205/581 (20130101) A61M 2205/582 (20130101) A61M 2205/583 (20130101) A61M 2205/586 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265527 | Lim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Hubert H. Lim (Minneapolis, Minnesota); Craig D. Markovitz (Minneapoils, Minnesota); Sarah J. Offutt (Minneapolis, Minnesota) |
| ABSTRACT | The invention provides methods for treating a neurological disorder or deficit, such as tinnitus and phantom limb pain. |
| FILED | Monday, February 18, 2013 |
| APPL NO | 14/395034 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/00 (20130101) A61F 11/00 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/0236 (20130101) A61H 2201/10 (20130101) A61H 2201/0207 (20130101) A61H 2201/1604 (20130101) A61H 2205/027 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/00 (20130101) A61M 2021/0027 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/361 (20130101) Original (OR) Class A61N 1/36025 (20130101) A61N 1/36036 (20170801) A61N 1/36067 (20130101) A61N 1/36071 (20130101) A61N 1/36082 (20130101) A61N 1/36096 (20130101) A61N 1/36167 (20130101) A61N 2/02 (20130101) A61N 2/006 (20130101) A61N 5/0622 (20130101) A61N 7/00 (20130101) A61N 2007/0026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265543 | Bharat et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands) |
| ASSIGNEE(S) | KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands); WASHINGTON UNIVERSITY (St. Louis, Mississippi) |
| INVENTOR(S) | Shyam Bharat (Ossining, New York); Mingyao Zhu (Manchester, Missouri); Parag Jitendra Parikh (Webster Groves, Missouri); Karl Antonin Bzdusek (Madison, Wisconsin) |
| ABSTRACT | A treatment planning system for generating patient-specific treatment. The system including one or more processors programmed to receive a radiation treatment plan (RTP) for irradiating a target over the course of one or more treatment fractions, said RTP including a planned dose distribution to be delivered to the target, receive motion data for at least one of the treatment fractions of the RTP, receive temporal delivery metric data for at least one of the treatment fractions of the RTP, calculate a motion-compensated dose distribution for the target using the motion data and the temporal delivery metric data to adjust the planned dose distribution based on the received motion data and temporal delivery metric data, and compare the motion-compensated dose distribution to the planned dose distribution. |
| FILED | Friday, November 30, 2012 |
| APPL NO | 14/358072 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1031 (20130101) Original (OR) Class A61N 5/1037 (20130101) A61N 5/1039 (20130101) A61N 5/1047 (20130101) A61N 5/1064 (20130101) A61N 5/1071 (20130101) A61N 5/1077 (20130101) A61N 7/02 (20130101) A61N 2005/1087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266488 | Maloney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eastern Virginia Medical School (Norfolk, Virginia); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SANTA CRUZ (Oakland, California); THE UNITED STATES OF AMERICA DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); Thomas Jefferson University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Eastern Virginia Medical School (Norfolk, Virginia); The Regents of the University of California Santa Cruz (Santa Cruz, California); The United States of America Department of Health and Human Services (Washington, District of Columbia); Thomas Jefferson University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | David J. Maloney (Point Of Rocks, Maryland); Diane K. Luci (Germantown, Maryland); Ajit Jadhav (Chantilly, Virginia); Theodore Holman (Santa Cruz, California); Jerry L. Nadler (Norfolk, Virginia); Michael Holinstat (Wallingford, Pennsylvania); David Taylor-Fishwick (Norfolk, Virginia); Anton Simeonov (Bethesda, Maryland); Adam Yasgar (Washington, District of Columbia); Steven McKenzie (Springfield, Pennsylvania) |
| ABSTRACT | Human lipoxygenases (LOXs) are a family of iron-containing enzymes involved in catalyzing the oxidation of polyunsaturated fatty acids to provide the corresponding bioactive hydroxyeicosatetraenoic acid (HETE) metabolites. These eicosanoid signaling molecules are involved in a number of physiologic responses such as platelet aggregation, inflammation, and cell proliferation. Platelet-type 12-(S)-LOX (12-LOX) is of particular interest because of its demonstrated role in skin diseases, diabetes, platelet hemostasis, thrombosis, and cancer. Disclosed herein is the identification and medicinal chemistry optimization of a 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide-based scaffold. The compounds display nM potency against 12-LOX and excellent selectivity over related lipoxygenases and cyclooxygenases. In addition to possessing favorable ADME properties, the compounds also inhibit PAR-4 induced aggregation and calcium mobilization in human platelets, and reduce 12-HETE in mouse/human beta cells. The compounds can also be used in methods for treating or preventing a 12-lipoxygenase mediated disease or disorder. |
| FILED | Friday, October 10, 2014 |
| APPL NO | 15/028386 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/02 (20180101) Acyclic or Carbocyclic Compounds C07C 311/44 (20130101) Original (OR) Class Heterocyclic Compounds C07D 211/28 (20130101) C07D 213/76 (20130101) C07D 217/02 (20130101) C07D 217/22 (20130101) C07D 235/30 (20130101) C07D 239/69 (20130101) C07D 261/16 (20130101) C07D 263/58 (20130101) C07D 277/52 (20130101) C07D 277/82 (20130101) C07D 295/135 (20130101) C07D 333/36 (20130101) C07D 417/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266490 | Rosen et al. |
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| FUNDED BY |
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| APPLICANT(S) | GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Eliot M. Rosen (Fairfax, Virginia); Milton Brown (Brookeville, Maryland); Saijun Fan (Bethesda, Maryland); Thomas Walls (Glenside, Pennsylvania); Kathryn E. Ditmer (Alexandrai, Virginia) |
| ABSTRACT | Radioprotector compounds including 3,3′-diindolylmethane (DIM) analogs, are provided. Further provided are methods for their use in reducing or preventing radiation damage, killing a tumor cell and protecting a non-tumor cell, and treating cancer. |
| FILED | Thursday, March 14, 2013 |
| APPL NO | 14/385575 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/341 (20130101) A61K 31/343 (20130101) A61K 31/404 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) A61N 2005/1094 (20130101) Heterocyclic Compounds C07D 207/16 (20130101) C07D 207/48 (20130101) C07D 209/18 (20130101) C07D 209/42 (20130101) C07D 209/58 (20130101) Original (OR) Class C07D 209/88 (20130101) C07D 307/42 (20130101) C07D 307/46 (20130101) C07D 407/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266503 | White et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | M. Christina White (Champaign, Illinois); Stephen E. Ammann (Champaign, Illinois); Wei Liu (Simi Valley, California); Rulin Ma (Urbana, Illinois) |
| ABSTRACT | The enantioselective synthesis of isochroman motifs has been accomplished via Pd(II)-catalyzed allylic C—H oxidation from terminal olefin precursors. Critical to the success of this goal was the development and utilization of a novel chiral aryl sulfoxide-oxazoline (ArSOX) ligand. The allylic C—H oxidation reaction proceeds with the broadest scope and highest levels asymmetric induction reported to date (avg. 92% ee, 13 examples ≥90% ee). Additionally, C(sp3)-N fragment coupling reaction between abundant terminal olefins and N-triflyl protected aliphatic and aromatic amines via Pd(II)/sulfoxide (SOX) catalyzed intermolecular allylic C—H amination is disclosed. A range of 52 allylic amines are furnished in good yields (avg. 76%) and excellent regio- and stereoselectivity (avg. >20:1 linear:branched, >20:1 E:Z). For the first time, a variety of singly activated aromatic and aliphatic nitrogen nucleophiles, including ones with stereochemical elements, can be used in fragment coupling stiochiometries for intermolecular C—H amination reactions. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 15/604377 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 317/14 (20130101) Heterocyclic Compounds C07D 263/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266505 | Edderkaoui et al. |
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| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Mouad Edderkaoui (Los Angeles, California); Ramachandran Murali (Swarthmore, Pennsylvania); Stephen Pandol (Los Angeles, California) |
| ABSTRACT | The invention describes compounds that inhibit both HDAC and GSK3β (i.e., HDAC/GSK3β dual inhibitors). The invention further describes compositions containing these HDAC/GSK3β dual inhibitors, as well as methods and kits using these HDAC/GSK3β dual inhibitors to treat various medical conditions. The invention also provides methods and kits using a HDAC inhibitor and a GSK3β to treat various medical conditions, and compositions containing a HDAC inhibitor and a GSK3β. Medical conditions treatable with various embodiments of the invention include but are not limited to cancers and tumors. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/012536 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/433 (20130101) A61K 31/433 (20130101) A61K 31/4245 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 271/10 (20130101) C07D 271/107 (20130101) C07D 271/113 (20130101) C07D 285/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266520 | Zimmerman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Steven C. Zimmerman (Champaign, Illinois); Long M. Luu (Urbana, Illinois); Lien T. T. Nguyen (Urbana, Illinois) |
| ABSTRACT | The invention provides compounds, compositions and therapeutic methods. The compounds and compositions can be used for the treatment of myotonic dystrophy. The compounds can selectively bind to CUG repeats in RNA, or to CTG repeats in DNA, and inhibit replication of the nucleic acids. RNA-targeted therapeutic agents for the treatment of myotonic dystrophy type 1 (DM1) are described. In one embodiment, two bisamidinium ligands are linked using “click” chemistry to form a heterodimer that is a potent inhibitor of the MBNL1-rCUGexp complex (KI=25±8 nM), is relatively non-toxic to HeLa cells, dissolves nuclear foci, corrects >80% of the IR misregulated alternative splicing in DM1 model cells (1 μM), and shows improvement of disease phenotypes in a DM1 Drosophila model. |
| FILED | Monday, August 10, 2015 |
| APPL NO | 15/502474 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Heterocyclic Compounds C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 403/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266544 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee) |
| INVENTOR(S) | Richard E. Lee (Cordova, Tennessee); Samanthi L. Waidyarachchi (Southaven, Mississippi); David F. Bruhn (Memphis, Tennessee); Jiuyu Liu (Bartlett, Tennessee); Zhong Zheng (Irvine, California); Jason W. Rosch (Memphis, Tennessee) |
| ABSTRACT | The invention relates to aryl substituted aminomethyl spectinomycin analogs, derivatives thereof, and related compounds, which are useful as anti-bacterial agents; methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating anti-bacterial infections using the compounds and compositions. |
| FILED | Monday, September 29, 2014 |
| APPL NO | 15/024549 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/357 (20130101) A61K 31/381 (20130101) A61K 31/427 (20130101) A61K 31/428 (20130101) A61K 31/497 (20130101) A61K 31/4025 (20130101) A61K 31/4045 (20130101) A61K 31/4178 (20130101) A61K 31/4433 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 493/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266549 | Shaw et al. |
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| FUNDED BY |
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| APPLICANT(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California); SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California); YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California); SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California); YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Reuben J. Shaw (La Jolla, California); Daniel F. Egan (La Jolla, California); Nicholas Cosford (La Jolla, California); Benjamin Turk (New Haven, Connecticut); Mitchell Vamos (La Jolla, California); Dhanya Raveendra Panickar (La Jolla, California); Matthew Chun (La Jolla, California); Douglas Sheffler (La Jolla, California) |
| ABSTRACT | In certain aspects, the invention provides a method for treating a disease or condition in a subject, the method comprising co-administering to a subject in need thereof a therapeutically effective amount of at least one ULK1-inhibiting pyrimidine, and a therapeutically effective amount of an mTOR inhibitor. |
| FILED | Tuesday, August 25, 2015 |
| APPL NO | 15/505532 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/5377 (20130101) A61K 31/5383 (20130101) A61K 31/5383 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 239/34 (20130101) C07D 239/42 (20130101) C07D 239/47 (20130101) C07D 239/48 (20130101) C07D 239/557 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 413/14 (20130101) C07D 417/04 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) C07D 471/04 (20130101) C07D 498/04 (20130101) Original (OR) Class Peptides C07K 7/08 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Enzymes C12Y 207/11001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/912 (20130101) G01N 2500/04 (20130101) G01N 2500/20 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266550 | Tse-Dinh et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Florida International University Board of Trustees (Miami, Florida); University of Hawaii (Honolulu, Hawaii) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida); UNIVERSITY OF HAWAII (Honolulu, Hawaii) |
| INVENTOR(S) | Yuk-Ching Tse-Dinh (Coral Gables, Florida); Dianqing Sun (Hilo, Hawaii) |
| ABSTRACT | The present invention provides compounds as bacterial topoisomerase inhibitors with antibacterial activity. The present invention also provides pharmaceutical compositions comprising at least one of the compounds and methods of using the compounds and pharmaceutical compositions as antibacterial agents for treating infectious diseases. |
| FILED | Monday, September 18, 2017 |
| APPL NO | 15/707537 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/538 (20130101) Heterocyclic Compounds C07D 498/04 (20130101) Original (OR) Class C07D 498/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266565 | Burke, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Terrence R. Burke, Jr. (Bethesda, Maryland); Fa Liu (Indianapolis, Indiana); Kyung S. Lee (Gaithersburg, Maryland); Jung-Eun Park (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Terrence R. Burke, Jr. (Bethesda, Maryland); Fa Liu (Indianapolis, Indiana); Kyung S. Lee (Gaithersburg, Maryland); Jung-Eun Park (Bethesda, Maryland) |
| ABSTRACT | Novel compounds are provided that bind to polo-like kinases through the polo-box domain. In certain embodiments, the novel compounds are PEGylated peptides. The PEGylated peptides in accordance with the invention demonstrate high PBD-binding affinity. In certain embodiments, the PEGylated peptides have also achieved activities in whole cell systems. The invention also provides compounds that bind polo-like kinases through the polo-box domain and possess reduced anionic charge. Further provided are methods of design and/or synthesis of the PEGylated peptides and methods of use thereof. The invention provides methods of use of the compounds and methods of synthesis of the compounds. |
| FILED | Thursday, April 12, 2012 |
| APPL NO | 14/111540 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/60 (20170801) Peptides C07K 1/006 (20130101) C07K 5/0827 (20130101) C07K 7/06 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Enzymes C12Y 207/11021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266573 | Chakrabarty et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ananda M. Chakrabarty (Villa Park, Illinois); Tapas K. Das Gupta (River Forest, Illinois); Vasu Punji (Chicago, Illinois); Olga Zaborina (Brookfield, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Ananda M. Chakrabarty (Villa Park, Illinois); Tapas K. Das Gupta (River Forest, Illinois); Vasu Punji (Chicago, Illinois); Olga Zaborina (Brookfield, Illinois) |
| ABSTRACT | Cytotoxic factors having use in modulating cell death, and their use in methods of treating necrosis or apoptosis-related conditions are disclosed. The invention also relates to methods for identifying active agents useful in treating conditions related to cell death. The present inventors have found that different pathogens produce different cytotoxic factor(s) having anticancer activity. The substantially pure cytotoxic factors can be used in a method of treating an infectious disease or a cancer. |
| FILED | Monday, May 19, 2008 |
| APPL NO | 12/123131 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/35 (20130101) Original (OR) Class C07K 14/195 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/569 (20130101) G01N 33/5011 (20130101) G01N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266580 | Scholler et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Nathalie Scholler (Narberth, Pennsylvania); Katarzyna Urbanska (Philadelphia, Pennsylvania); Daniel J. Powell, Jr. (Bala Cynwyd, Pennsylvania) |
| ABSTRACT | The invention provides compositions and methods for adoptive T cell therapy in treating a variety of disorders including cancer, infections, and autoimmune disorders. In one embodiment, the invention provides a universal immune receptor (UnivIR) that comprises an extracellular label binding domain, a transmembrane domain, and a cytoplasmic domain or otherwise an intracellular domain. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/591910 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6851 (20170801) Peptides C07K 14/465 (20130101) C07K 14/7051 (20130101) Original (OR) Class C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) C07K 2319/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266586 | James |
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| FUNDED BY |
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| APPLICANT(S) | THE MEDICAL COLLEGE OF WISCONSIN, INC. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Michael A. James (Big Bend, Wisconsin) |
| ABSTRACT | Provided herein are therapeutic agents having specificity for human CLPTM1 L polypeptide, including therapeutic agents comprising one or more CLPTM1 L-targeting agents, compositions comprising such therapeutic agents, and methods of using such compositions for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1 L protein dysfunction (e.g., pathogenic production, modification, or function). |
| FILED | Tuesday, January 06, 2015 |
| APPL NO | 15/111445 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/395 (20130101) A61K 39/39558 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 16/303 (20130101) C07K 16/3015 (20130101) C07K 16/3023 (20130101) C07K 16/3038 (20130101) C07K 16/3046 (20130101) C07K 16/3053 (20130101) C07K 16/3069 (20130101) C07K 2317/34 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266620 | Wen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Innovative Surface Technologies, Inc. (St. Paul, Minnesota) |
| ASSIGNEE(S) | Innovative Surface Technologies, Inc. (St. Paul, Minnesota) |
| INVENTOR(S) | Jie Wen (St. Johns, Florida); Kristin Taton (Little Canada, Minnesota); Laurie Lawin (New Brighton, Minnesota); William Knopke (Minneapolis, Minnesota); Eric Guire (St. Paul, Minnesota); Patrick Guire (Hopkins, Minnesota) |
| ABSTRACT | The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied. The coating agents are useful for providing a coating that can be further functionalized (for example, by application of additional coating layers), or for providing desirable properties to a surface. |
| FILED | Tuesday, December 06, 2016 |
| APPL NO | 15/370410 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/06 (20130101) A61L 29/14 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 31/06 (20130101) A61L 31/10 (20130101) A61L 31/14 (20130101) A61L 31/16 (20130101) A61L 31/022 (20130101) A61L 33/0005 (20130101) A61L 2300/42 (20130101) A61L 2300/404 (20130101) A61L 2400/10 (20130101) A61L 2420/02 (20130101) A61L 2420/08 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 3/06 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/28 (20130101) C08F 8/30 (20130101) C08F 8/30 (20130101) C08F 8/42 (20130101) Original (OR) Class C08F 8/42 (20130101) C08F 222/06 (20130101) C08F 222/06 (20130101) C08F 267/04 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 131/00 (20130101) C09D 135/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/3175 (20150401) Y10T 428/31507 (20150401) Y10T 428/31511 (20150401) Y10T 428/31573 (20150401) Y10T 428/31598 (20150401) Y10T 428/31663 (20150401) Y10T 428/31667 (20150401) Y10T 428/31721 (20150401) Y10T 428/31797 (20150401) Y10T 428/31855 (20150401) Y10T 428/31884 (20150401) Y10T 428/31909 (20150401) Y10T 428/31913 (20150401) Y10T 428/31928 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266684 | James et al. |
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| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Susan P. James (Bellvue, Colorado); Hieu Bui (Fort Collins, Colorado) |
| ABSTRACT | Provided herein is a composite, comprising: a polymer host selected from the group consisting of low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), polypropylene (PP), polyurethane, polycaprolactone (PCL), polydimethylsiloxane (PDMS), polymethylmethacrylate (PMMA), and polyoxymethylene (POM); and a guest molecule comprising hyaluronic acid; wherein the guest molecule is disposed within the polymer host, and wherein the guest molecule is covalently bonded to at least one other guest molecule. Also provided herein are methods for forming the composite, and blood-contracting devices made from the composite, such as heart valves and vascular grafts. |
| FILED | Monday, July 02, 2018 |
| APPL NO | 16/025255 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/011 (20180101) C08K 5/205 (20130101) Compositions of Macromolecular Compounds C08L 23/06 (20130101) Original (OR) Class C08L 2207/066 (20130101) C08L 2312/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266804 | Hickman et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | James Hickman (Orlando, Florida); Mainak Das (Orlando, Florida) |
| ABSTRACT | The invention provides a method of co-culturing mammalian muscle cells and mammalian motoneurons. The method comprises preparing one or more carriers coated with a covalently bonded monolayer of trimethoxysilylpropyl diethylenetriamine (DETA); suspending isolated fetal mammalian skeletal muscle cells in serum-free medium according to medium composition 1; suspending isolated fetal mammalian spinal motoneurons in serum-free medium according to medium composition 1; plating the suspended muscle cells onto the one or more carriers at a predetermined density and allowing the muscle cells to attach; plating the suspended motoneurons at a predetermined density onto the one or more carriers and allowing the motoneurons to attach; covering the one or more carriers with a mixture of medium composition 1 and medium composition 2; and incubating the carriers covered in the media mixture. |
| FILED | Monday, May 15, 2017 |
| APPL NO | 15/594895 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 5/0658 (20130101) C12N 2500/90 (20130101) C12N 2502/088 (20130101) C12N 2502/1335 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266822 | Singh et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Ravindra N. Singh (Shrewsbury, Massachusetts); Natalia N. Singh (Shrewsbury, Massachusetts); Nirmal K. Singh (Temple, Texas); Elliot J. Androphy (Natick, Massachusetts) |
| ABSTRACT | The present invention is directed to methods and compositions capable of blocking the inhibitory effect of a newly-identified intronic inhibitory sequence element, named ISS-N1 (for “intronic splicing silencer”), located in the SMN2 gene. The compositions and methods of the instant invention include oligonucleotide reagents (e.g., oligoribonucleotides) that effectively target the SMN2 ISS-N1 site in the SMN2 pre-mRNA, thereby modulating the splicing of SMN2 pre-mRNA to include exon 7 in the processed transcript. The ISS-N1 blocking agents of the invention cause elevated expression of SMN protein, thus compensating for the loss of SMN protein expression commonly observed in subjects with spinal muscular atrophy (SMA). |
| FILED | Monday, September 19, 2016 |
| APPL NO | 15/269259 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/322 (20130101) C12N 2320/33 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2500/04 (20130101) G01N 2800/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266823 | Juliano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Southern Research Institute (Birmingham, Alabama) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Southern Research Institute (Birmingham, Alabama) |
| INVENTOR(S) | Rudolph Juliano (Chapel Hill, North Carolina); William P. Janzen (Chapel Hill, North Carolina); Joseph A. Maddry (Birmingham, Alabama); Canhong Cao (Chapel Hill, North Carolina); Xin Ming (Chapel Hill, North Carolina); Bing Yang (Chapel Hill, North Carolina) |
| ABSTRACT | Methods of administering an oligonucleotide of interest into a cell in vitro or in vivo are described. In the methods, a small organic compound active agent is concurrently administered to the cell in an amount effective to increase the delivery of the oligonucleotide into the cell, and/or increase the activity of said oligonucleotide in the cell. Compositions useful for carrying out the method are also described. |
| FILED | Friday, June 26, 2015 |
| APPL NO | 15/318260 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 31/7088 (20130101) A61K 31/7088 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/346 (20130101) C12N 2310/351 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266826 | Orkin et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Stuart H. Orkin (Brookline, Massachusetts); Vijay G. Sankaran (Jamaica Plain, Massachusetts) |
| ABSTRACT | The invention relates to methods and uses of modulating fetal hemoglobin expression (HbF) in a hematopoietic progenitor cells via inhibitors of BCL11A expression or activity, such as RNAi and antibodies. |
| FILED | Monday, February 05, 2018 |
| APPL NO | 15/888350 |
| ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/15 (20130101) A01K 2217/052 (20130101) A01K 2227/105 (20130101) A01K 2267/0381 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 35/28 (20130101) A61K 49/00 (20130101) Peptides C07K 14/805 (20130101) C07K 14/4705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/8509 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2740/15043 (20130101) C12N 2800/206 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266827 | Wilton et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Western Australia (Crawley, Australia) |
| ASSIGNEE(S) | The University of Western Australia (Crawley, Australia) |
| INVENTOR(S) | Stephen Donald Wilton (Applecross, Australia); Sue Fletcher (Bayswater, Australia); Graham McClorey (Bayswater, Australia) |
| ABSTRACT | An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 214. |
| FILED | Friday, August 24, 2018 |
| APPL NO | 16/112453 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/33 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/3233 (20130101) C12N 2310/3341 (20130101) C12N 2310/3519 (20130101) C12N 2320/30 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266844 | Anderson et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | David J. Anderson (Altadena, California); Todd E. Anthony (Pasadena, California) |
| ABSTRACT | According to some embodiments herein, expression systems and methods for activity-dependent transcription of nucleic acids are provided. In some embodiments, adeno-associated viral vector systems comprise an immediate early gene promoter operably linked to a transcriptional activator. The transcription activator can be fused to an N-terminal portion of an immediate early gene, for example fos. |
| FILED | Thursday, July 28, 2016 |
| APPL NO | 15/222554 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/052 (20130101) Peptides C07K 14/82 (20130101) C07K 2319/00 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14143 (20130101) C12N 2800/30 (20130101) C12N 2830/002 (20130101) C12N 2830/003 (20130101) C12N 2830/006 (20130101) C12N 2830/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266846 | Gao et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Guangping Gao (Westborough, Massachusetts); James M. Wilson (Glen Mills, Pennsylvania); Mauricio R. Alvira (Philadelphia, Pennsylvania) |
| ABSTRACT | Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. |
| FILED | Thursday, October 20, 2016 |
| APPL NO | 15/298760 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/761 (20130101) A61K 38/45 (20130101) A61K 38/177 (20130101) A61K 38/4846 (20130101) A61K 48/00 (20130101) Peptides C07K 14/005 (20130101) C07K 14/705 (20130101) C07K 14/755 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/644 (20130101) C12N 9/1018 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 15/8645 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14152 (20130101) C12N 2830/008 (20130101) C12N 2830/48 (20130101) C12N 2830/85 (20130101) Enzymes C12Y 201/03003 (20130101) C12Y 304/21021 (20130101) C12Y 304/21022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266847 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Pin Wang (Arcadia, California); Lili Yang (Arcadia, California); David Baltimore (Pasadena, California) |
| ABSTRACT | Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers. |
| FILED | Wednesday, November 22, 2017 |
| APPL NO | 15/820741 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/70 (20130101) A61K 35/76 (20130101) A61K 38/20 (20130101) A61K 38/20 (20130101) A61K 38/177 (20130101) A61K 38/177 (20130101) A61K 38/178 (20130101) A61K 38/178 (20130101) A61K 38/191 (20130101) A61K 38/191 (20130101) A61K 38/193 (20130101) A61K 38/193 (20130101) A61K 38/204 (20130101) A61K 38/1774 (20130101) A61K 38/1793 (20130101) A61K 38/2013 (20130101) A61K 38/2026 (20130101) A61K 38/2046 (20130101) A61K 38/2086 (20130101) A61K 39/21 (20130101) A61K 2039/5256 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2740/13043 (20130101) C12N 2740/13045 (20130101) C12N 2740/15041 (20130101) C12N 2740/15043 (20130101) C12N 2740/15045 (20130101) C12N 2770/36122 (20130101) C12N 2770/36134 (20130101) C12N 2810/609 (20130101) C12N 2810/855 (20130101) Technologies for Adaptation to Climate Change Y02A 50/41 (20180101) Y02A 50/48 (20180101) Y02A 50/386 (20180101) Y02A 50/396 (20180101) Y02A 50/401 (20180101) Y02A 50/403 (20180101) Y02A 50/407 (20180101) Y02A 50/412 (20180101) Y02A 50/423 (20180101) Y02A 50/466 (20180101) Y02A 50/475 (20180101) Y02A 50/481 (20180101) Y02A 50/492 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266848 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Yi Zhang (Boston, Massachusetts); Shogo Matoba (Boston, Massachusetts) |
| ABSTRACT | The present invention provides methods and compostions to improve the efficiency of somatic cell nuclear transfer (SCNT) and the consequent production of nuclear transfer ESC (ntESC) and transgenic cells and/or non-human animals. More specifically, the present invention relates to the discovery that trimethylation of Histone H3-Lysine 9 (H3K9me3) in reprogramming resistant regions (RRRs) in the nuclear genetic material of donor somatic cells prevents efficient somatic cell nuclear reprogramming or SCNT. The present invention provide methods and compositions to decrease H3K9me3 in methods to improve efficacy of SCNT by exogenous or overexpression of the demethylase Kdm4 family and/or inhibiting methylation of H3K9me3 by inhibiting the histone methyltransferases Suv39h1 and/or Suv39h2. |
| FILED | Monday, June 25, 2018 |
| APPL NO | 16/017157 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0273 (20130101) A01K 2227/105 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0604 (20130101) C12N 5/0606 (20130101) C12N 15/877 (20130101) Original (OR) Class C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2517/04 (20130101) Enzymes C12Y 201/01043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266850 | Doudna et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); University of Vienna (Vienna, Austria); Emmanuelle Charpentier (Braunschweig, Germany) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); University of Vienna (Vienna, Austria); Emmanuelle Charpentier (Braunschweig, Germany) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Martin Jinek (Berkeley, California); Emmanuelle Charpentier (Braunschweig, Germany); Krzysztof Chylinski (Vienna, Austria) |
| ABSTRACT | The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 13/842859 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/4684 (20180501) Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/027 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/70 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/746 (20130101) C12N 15/902 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/13 (20130101) C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2310/31 (20130101) C12N 2310/32 (20130101) C12N 2310/33 (20130101) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 301/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266876 | Cai et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Long Cai (Port Jefferson Station, New York); Eric Lubeck (Pasadena, California) |
| ABSTRACT | Methods and systems are provided for creating molecular barcodes or indicia for cellular constituents within single cells and for resolving such barcodes or indicia with super-resolution technologies such as super-resolution microscopy. By this approach, numerous molecular species that can be measured simultaneously in single cells. It has been demonstrated that multiple mRNA transcripts can be labeled with a spatially ordered sequence of fluorophores, and that barcodes can be resolved. In addition, alternative splicing events can be characterized by identifying and quantifying mRNA isoforms in an individual cell. |
| FILED | Friday, December 21, 2012 |
| APPL NO | 13/725717 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) Original (OR) Class C12Q 1/6841 (20130101) C12Q 1/6841 (20130101) C12Q 2543/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266883 | Chee |
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| FUNDED BY |
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| APPLICANT(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| ASSIGNEE(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Mark S. Chee (Encinitas, California) |
| ABSTRACT | The present invention provides oligonucleotide constructs, sets of such oligonucleotide constructs, and methods of using such oligonucleotide constructs to provide validated sequences or sets of validated sequences corresponding to desired ROIs. Such validated ROIs and constructs containing these have a wide variety of uses, including in synthetic biology, quantitative nucleic acid analysis, polymorphism and/or mutation screening, and the like. |
| FILED | Friday, November 11, 2016 |
| APPL NO | 15/349906 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6834 (20130101) C12Q 1/6834 (20130101) C12Q 1/6834 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/131 (20130101) C12Q 2525/131 (20130101) C12Q 2525/131 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2539/103 (20130101) C12Q 2539/103 (20130101) C12Q 2539/103 (20130101) C12Q 2563/149 (20130101) C12Q 2563/149 (20130101) C12Q 2563/149 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266884 | Chee |
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| FUNDED BY |
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| APPLICANT(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| ASSIGNEE(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Mark S. Chee (Encinitas, California) |
| ABSTRACT | The present invention provides oligonucleotide constructs, sets of such oligonucleotide constructs, and methods of using such oligonucleotide constructs to provide validated sequences or sets of validated sequences corresponding to desired ROIs. Such validated ROIs and constructs containing these have a wide variety of uses, including in synthetic biology, quantitative nucleic acid analysis, polymorphism and/or mutation screening, and the like. |
| FILED | Wednesday, December 07, 2016 |
| APPL NO | 15/372159 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6834 (20130101) C12Q 1/6834 (20130101) C12Q 1/6834 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/131 (20130101) C12Q 2525/131 (20130101) C12Q 2525/131 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2539/103 (20130101) C12Q 2539/103 (20130101) C12Q 2539/103 (20130101) C12Q 2563/149 (20130101) C12Q 2563/149 (20130101) C12Q 2563/149 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266886 | Abudayyeh et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTED OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Omar Abudayyeh (Cambridge, Massachusetts); James Joseph Collins (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Feng Zhang (Cambridge, Massachusetts); Eric S. Lander (Cambridge, Massachusetts) |
| ABSTRACT | The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/917546 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6811 (20130101) C12Q 1/6816 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/51 (20180101) Y02A 50/53 (20180101) Y02A 50/58 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266887 | Abudayyeh et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Omar Abudayyeh (Cambridge, Massachusetts); James Joseph Collins (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Feng Zhang (Cambridge, Massachusetts); Eric S. Lander (Cambridge, Massachusetts) |
| ABSTRACT | The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/917549 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6811 (20130101) C12Q 1/6816 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/51 (20180101) Y02A 50/53 (20180101) Y02A 50/58 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266888 | Daugharthy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Evan R. Daugharthy (Cambridge, Massachusetts); Richard C. Terry (Carlisle, Massachusetts); Je-Hyuk Lee (Allston, Massachusetts); George M. Church (Brookline, Massachusetts); Benjamin W. Pruitt (Cambridge, Massachusetts) |
| ABSTRACT | Methods of volumetric imaging of a three-dimensional matrix of nucleic acids within a cell is provided. An automated apparatus for sequencing and volumetric imaging of a three-dimensional matrix of nucleic acids is provided. |
| FILED | Wednesday, May 02, 2018 |
| APPL NO | 15/969118 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6841 (20130101) C12Q 1/6841 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2543/101 (20130101) C12Q 2543/101 (20130101) C12Q 2563/159 (20130101) C12Q 2563/159 (20130101) C12Q 2565/601 (20130101) C12Q 2565/601 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266892 | Esfandyarpour et al. |
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| FUNDED BY |
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| APPLICANT(S) | GenapSys, Inc. (Redwood City, California) |
| ASSIGNEE(S) | GENAPSYS, INC. (Redwood City, California) |
| INVENTOR(S) | Hesaam Esfandyarpour (Redwood City, California); Kosar Baghbani Parizi (Redwood City, California); Mark F. Oldham (Emerald Hills, California); Eric S. Nordman (Palo Alto, California); Richard T. Reel (Hayward, California); Susanne Baumhueter (Redwood City, California); Cheryl Heiner (La Honda, California); Frank Lee (Irvine, California) |
| ABSTRACT | The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices. |
| FILED | Wednesday, June 13, 2018 |
| APPL NO | 16/007969 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 2527/119 (20130101) C12Q 2527/119 (20130101) C12Q 2549/126 (20130101) C12Q 2563/116 (20130101) C12Q 2563/116 (20130101) C12Q 2565/607 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/327 (20130101) G01N 33/5438 (20130101) G01N 33/54313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266893 | Rabinowitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Natera, Inc. (San Carlos, California) |
| ASSIGNEE(S) | Natera, Inc. (San Carlos, California) |
| INVENTOR(S) | Matthew Rabinowitz (San Francisco, California); Milena Banjevic (Los Altos Hills, California); Zachary Demko (San Francisco, California); David Johnson (San Francisco, California); Dusan Kijacic (Los Altos Hills, California); Dimitri Petrov (Stanford, California); Joshua Sweetkind-Singer (San Jose, California); Jing Xu (Jersey City, New Jersey) |
| ABSTRACT | Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment, the chromosome copy number can be determined from the measured genetic data, with or without genetic information from one or both parents. |
| FILED | Friday, January 26, 2018 |
| APPL NO | 15/881384 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6848 (20130101) C12Q 1/6851 (20130101) C12Q 1/6855 (20130101) C12Q 1/6855 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 2525/155 (20130101) C12Q 2535/122 (20130101) C12Q 2537/16 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Electric Digital Data Processing G06F 19/18 (20130101) G06F 19/24 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267754 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Yihua Bruce Yu (Baltimore, Maryland); Marc Taraban (Baltimore, Maryland); Yue Feng (Baltimore, Maryland) |
| ABSTRACT | The present invention generally relates to a method of using NMR relaxation rates (R2) of water molecules as an indicator of the extent of aggregation of biopharmaceutical formulations. The biopharmaceutical can be evaluated nondestructively without the vial or container being opened or protective seal compromised (i.e., broken). The method is applicable to all biopharmaceuticals and the water signal obtained by magnetic resonance relaxometry is very strong and sensitive because water is used as the solvent and is present in high (>90%) concentrations in every biopharmaceutical formulation. |
| FILED | Friday, April 11, 2014 |
| APPL NO | 14/780711 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/08 (20130101) Original (OR) Class G01N 33/15 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/448 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267785 | Lindsay et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Stuart Lindsay (Phoenix, Arizona); Peiming Zhang (Gilbert, Arizona) |
| ABSTRACT | Embodiments of the present disclosure are directed to methods, systems and devices, for analyzing the molecules. For example, in some embodiments, a system is provided which includes a first volume of conducting fluid, a second volume of conducting fluid, an orifice in communication with the first and second volumes of fluid, and means for applying an electric potential difference between the first and second volumes of fluid. In some such embodiments, a conjugate product is provided which includes charged polymers each having attached thereto at least one first molecule for analysis, where the product carries a predetermined charge greater than the charge on the first molecule, and upon dissolving the product in the first volume of fluid, the product is directed into the orifice. |
| FILED | Thursday, March 15, 2018 |
| APPL NO | 15/922436 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/12 (20130101) G01N 27/44704 (20130101) G01N 27/44747 (20130101) G01N 27/44756 (20130101) G01N 33/5438 (20130101) G01N 33/6803 (20130101) G01N 33/6848 (20130101) G01N 33/48721 (20130101) Original (OR) Class G01N 2333/952 (20130101) G01N 2570/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/255 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267786 | Yuan |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Baohong Yuan (Arlington, Texas) |
| ABSTRACT | In one aspect, methods of imaging are described herein. In some embodiments, a method of imaging described herein comprises disposing a population of ultrasound-switchable fluorophores in a biological environment, the fluorophores having a switching threshold between an off state and an on state; exposing the biological environment to an ultrasound beam to create an activation region within the biological environment; switching at least one of the fluorophores within the activation region from the off state to the on state; exciting the at least one fluorophore with a beam of electromagnetic radiation; and detecting light emitted by the fluorophore. In some embodiments, the activation region has a maximum negative pressure and/or maximum temperature and the switching threshold of the at least one fluorophore is at least about 50 percent of the maximum negative pressure or at least about 50 percent of the maximum temperature of the activation region. |
| FILED | Thursday, January 23, 2014 |
| APPL NO | 14/162375 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0028 (20130101) A61K 49/0034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/5091 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267795 | Herr et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Amy E. Herr (Oakland, California); Alex James Hughes (Berkeley, California); Elly Sinkala (Oakland, California); Todd A. Duncombe (Berkeley, California); Kevin A. Yamauchi (Berkeley, California); Julea Vlassakis (Berkeley, California); Chi-Chih Kang (Berkeley, California); Zhuchen Xu (Berkeley, California); Robert Lin (Berkeley, California) |
| ABSTRACT | Electrophoretic separation devices and methods for using the same are provided. Aspects of the devices include a polymeric separation medium that includes a plurality of microwells. Also provided are methods, systems and kits in which the subject devices find use. The devices and methods find use in a variety of different electrophoretic separation applications. |
| FILED | Thursday, March 06, 2014 |
| APPL NO | 14/650520 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44726 (20130101) G01N 27/44747 (20130101) G01N 27/44791 (20130101) G01N 33/561 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267808 | Cai |
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| FUNDED BY |
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| APPLICANT(S) | Long Cai (Port Jefferson Station, New York) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Long Cai (Port Jefferson Station, New York) |
| ABSTRACT | Methods and systems are provided for creating molecular barcodes or indicia for cellular constituents within single cells and for resolving such barcodes or indicia with super resolution technologies such as super resolution microscopy. By this approach, numerous molecular species that can be measured simultaneously in single cells. It has been demonstrated that multiple mRNA transcripts can be labeled with a spatially ordered sequence of fluorophores, and that barcode can be resolved. The methods and systems can be used for genome-wide transcriptional profiling in individual cells by super-resolution barcoding and suggest a general strategy to bring large-scale-omics approach into single cells. |
| FILED | Tuesday, March 08, 2011 |
| APPL NO | 13/043413 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) C12Q 1/6841 (20130101) C12Q 2543/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267837 | Bassen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Howard Bassen (Chevy Chase, Maryland); Gonzalo Mendoza (Sterling, Virginia); Amir Razjouyan (Annandale, Virginia); Mohammed Eslami (Gaithersburg, Maryland); Negin Shahshahan (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure is directed to an apparatus for detecting low level pulses of millimeter wave electromagnetic radiation, such as by detecting the presence of weak electromagnetic emissions inside or around an electromagnetic radiation-emitting device, such as a millimeter wave scanner. The apparatus may also be used to assess such emissions and display a graphical and numerical indication of a sensed level of energy density. A hand-held portable apparatus for detecting low levels of electromagnetic radiation as well as a method for detecting low levels of electromagnetic radiation are also provided. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/031353 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/0878 (20130101) Original (OR) Class G01R 33/285 (20130101) G01R 33/287 (20130101) G01R 33/383 (20130101) G01R 33/3808 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267871 | Osterfeld et al. |
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| FUNDED BY |
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| APPLICANT(S) | MagArray, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | MagArray, Inc. (Milpitas, California) |
| INVENTOR(S) | Sebastian J. Osterfeld (Mountain View, California); Shan Xiang Wang (Palo Alto, California) |
| ABSTRACT | Provided are magnetic sensors, which include a magnetic tunnel junction (MTJ) magnetoresistive element, a first electrode contacting at least a portion of a surface of the MTJ magnetoresistive element and extending beyond an edge of the surface of the MTJ magnetoresistive element, and a second electrode contacting at least a portion of an opposing surface of the MTJ magnetoresistive element and extending beyond an edge of the opposing surface of the MTJ magnetoresistive element, where facing surfaces of the extending portions of the first and second electrodes are non-overlapping. Also provided are devices, systems and methods in which the subject magnetic sensors find use. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/209863 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/745 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/098 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267880 | Feldman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Rebecca Emily Feldman (New York, New York); Haisam Mohammad Islam (Stanford, California); Priti Balchandani (New York, New York) |
| ABSTRACT | A method, magnetic resonance imaging computing device, and a non-transitory computer readable medium for producing a pulse pair for magnetic resonance imaging. A pulse pair control signal comprising an adiabatic pulse and a matched phase non-adiabatic pulse is generated. The pulse pair control signal is transformed into a power independent of number of slices pulse pair. The Power Independent of Number of Slices pulse pair control signal is output to a waveform generator to produce the Power Independent of Number of Slices pulse pair in a spin echo sequence. |
| FILED | Monday, April 27, 2015 |
| APPL NO | 14/697040 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/58 (20130101) G01R 33/288 (20130101) G01R 33/4806 (20130101) G01R 33/4835 (20130101) Original (OR) Class G01R 33/5659 (20130101) G01R 33/56341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267881 | Song et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Xiaolei Song (Baltimore, Maryland); Michael McMahon (Columbia, Maryland) |
| ABSTRACT | CEST MR imaging, called Multi-echo Parametric VARiation Saturation (Me-PaVARS) CEST places multiple image readouts in between a series of saturation pulses. The saturation pulse parameters are varied in a designated systematic pattern, which allows the generation of CEST contrast maps by encoding the patterns of signal loss into the images for better discrimination between various CEST imaging agents. The saturation parameter changes include, but are not limited to, saturation amplitude (B1), saturation length (tsat), number of pulses, shape of saturation pulses, amplitude of saturation pulses, saturation offset frequency, or a combination of these variations. |
| FILED | Friday, December 18, 2015 |
| APPL NO | 14/973897 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/7257 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5601 (20130101) G01R 33/5605 (20130101) Original (OR) Class G01R 33/5616 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267886 | Bernstein et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Matthew A. Bernstein (Rochester, Minnesota); Joshua D. Trzasko (Rochester, Minnesota); Shengzhen Tao (Rochester, Minnesota) |
| ABSTRACT | A system and method for simultaneously reconstructing magnetic resonance images and correcting those imaged for gradient nonlinearity effects are provided. As opposed to conventional methods for gradient nonlinearity correction where distortion is corrected after image reconstruction is performed, the model-based method described here prospectively accounts for the effects of gradient nonlinearity during reconstruction and implements a spatial support constraint to reduce noise amplification effects. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/953657 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/58 (20130101) G01R 33/482 (20130101) G01R 33/561 (20130101) G01R 33/4824 (20130101) G01R 33/5611 (20130101) G01R 33/56572 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10269340 | Yen |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Jesse Yen (La Crescenta, California) |
| ABSTRACT | An ultrasound beamformer may include an array of ultrasound transducer elements. Multiple signal transmitters may each generate an ultrasound signal that is different from the ultrasound signal generated by each of the others. The number of ultrasound transmitters may be no more than half the number of ultrasound transducer elements. Each multiplexer may have multiple signal inputs, each connected to a different one of the ultrasound signals; an output that drives the ultrasound transducer element; and a control input that controls which of the ultrasound signals at the signal inputs to the multiplexer is delivered to the output of the multiplexer based on a control signal. The controller may generate the control signals with a collective configuration that causes the array of ultrasound transducer elements to steer an/or focus a beam of ultrasound energy in one or more different ways at one or more different times. |
| FILED | Friday, June 14, 2013 |
| APPL NO | 14/408250 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/5202 (20130101) G01S 15/8915 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/34 (20130101) Original (OR) Class G10K 11/346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10269550 | Ouyang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Zheng Ouyang (West Lafayette, Indiana); Yue Ren (West Lafayette, Indiana); Ziqing Lin (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to systems and methods for quantifying an analyte extracted from a sample. In certain embodiments, the invention provides methods that involve introducing a solvent into a capillary, introducing the capillary into a vessel including a sample such that a portion of the sample is introduced into the capillary, moving the sample and the solvent within the capillary to induce circulation within the sample and the solvent, thereby causing the analyte to be extracted from the sample and into the solvent, analyzing the analyte that has been extracted from the sample, and quantifying the analyte. In certain embodiments, the quantifying step is performed without knowledge of a volume of the sample and/or solvent. |
| FILED | Wednesday, March 09, 2016 |
| APPL NO | 15/064865 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/167 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/24 (20150115) Y10T 436/255 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10264986 | Galea |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vivonics, Inc. (Bedford, Massachusetts) |
| ASSIGNEE(S) | Vivonics, Inc. (Bedford, Massachusetts) |
| INVENTOR(S) | Anna M Galea (Stow, Massachusetts) |
| ABSTRACT | A system which includes a first sensor placed proximate to a perfusion field of an artery receiving blood which emanates from the cranial cavity is configured to monitor pulsations of the artery receiving blood which emanates from the cranial cavity artery. A second sensor placed proximate to a perfusion field of an artery which does not receive blood emanating from the cranial cavity configured to monitor pulsations of the artery which does not receive blood emanating from the cranial cavity. A third sensor configured to monitor pulsations of a distal artery. A processing system responsive to signals from the first, second, and third sensors is configured to determine intracranial pressure. |
| FILED | Thursday, December 28, 2017 |
| APPL NO | 15/856400 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/031 (20130101) Original (OR) Class A61B 5/742 (20130101) A61B 5/02438 (20130101) A61B 5/6814 (20130101) A61B 5/6815 (20130101) A61B 5/6824 (20130101) A61B 5/6825 (20130101) A61B 5/6826 (20130101) A61B 5/7246 (20130101) A61B 5/7278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10264988 | Nugent et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Brian Nugent (Acton, Massachusetts); Robert Bousquet (Waltham, Massachusetts); Jesse J. Wheeler (Boston, Massachusetts); Andrew Czarnecki (Cambridge, Massachusetts); John Lachapelle (Princeton, Massachusetts) |
| ABSTRACT | Systems and methods are disclosed herein for recording electrical signals in the presence of artifacts. The system and methods can employ multiple techniques for attenuating large, unwanted artifacts while preserving lower amplitude desirable signals. Aspects that can improve the recording of electrical signals in the presence of larger artifacts include particular electrode placement and spacing, high dynamic range amplification with good linearity, and signal blanking. Combinations of more or fewer techniques can be employed to achieve the desired attenuation of signal artifacts while preserving the desired signal. The systems and methods are suitable for recording neural signals in the presence of electrical stimulation signals. |
| FILED | Friday, May 20, 2016 |
| APPL NO | 15/160500 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/725 (20130101) A61B 5/04001 (20130101) Original (OR) Class A61B 5/7203 (20130101) A61B 5/7225 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36139 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10264999 | Lacirignola et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Joseph J. Lacirignola (Beverly, Massachusetts); Trina Rae Vian (Westford, Massachusetts); Christopher J. Smalt (Arlington, Massachusetts); David F. Aubin, Jr. (Pelham, New Hampshire); David C. Maurer (Stoneham, Massachusetts); Mary Katherine Byrd (Arlington, Massachusetts); Christine M. Weston (Cambridge, Massachusetts); Kerry A. Johnson (Somerville, Massachusetts); Shakti Davis (Arlington, Massachusetts); Olha Townsend (Providence, Rhode Island); Paul T. Calamia (Framingham, Massachusetts); Edward H. Chen (Woodland Hills, California); Paula P. Collins (Arlington, Massachusetts) |
| ABSTRACT | Systems, apparatus, and methods for collecting, interpreting, and utilizing noise exposure data may include sensors to obtain an analog signal representative of impulse noise sound pressure and an analog signal representative of continuous noise sound pressure. At least one ADC may generate digital signals by sampling the analog signals at rates equal to or greater than twice the reciprocal of a minimum impulse noise rise time. Accelerometers may obtain data in close proximity to and remote from the sensors. At least one processor may include a first combining node to combine the digital signals to represent both the continuous noise and the impulse noise, a shock-artifact detection filter to identify a time frame including a shock artifact based on the accelerometry data, a frequency filter to generate a background-removed audio signal, an adaptive filter to estimate the shock artifact, and a second combining node to produce a shock-artifact-free audio signal. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/863027 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/125 (20130101) Original (OR) Class A61B 5/721 (20130101) A61B 5/6814 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 3/12 (20130101) G01H 3/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265008 | Durkee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aptima, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | Aptima, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Kevin Durkee (Beavercreek, Ohio); Scott Pappada (Fairborn, Ohio); Andres Ortiz (Simi Valley, California); William DePriest (Dayton, Ohio); John Feeney (Beavercrek, Ohio); Alexandra Geyer (Winchester, Massachusetts); Seamus Sullivan (Oakwood, Ohio); Sterling Wiggins (Yellow Springs, Ohio) |
| ABSTRACT | Computer based systems and methods for estimating a user state are disclosed. In some embodiments, the methods comprise inputting a first input at an intermittent interval and a second input at a frequent interval into a user state estimation model to estimate the user state. In some embodiments, the first inputs are enhanced by injecting a noise input to create a plurality of enhanced first inputs whereby the plurality of enhance first inputs correspond to the plurality of second inputs at the frequent interval. In some embodiments, the first input comprises a self-reported input and the second inputs comprise a physiological input, a performance input or a situational input. In some embodiments, a machine learning algorithm creates the state estimation model. In some embodiments, the state estimation model estimates a future user state. In some embodiments, a computer based system for estimating a user state is provided. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/772827 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) Original (OR) Class A61B 5/0476 (20130101) A61B 5/04012 (20130101) A61B 5/7203 (20130101) A61B 5/7246 (20130101) A61B 5/7267 (20130101) A61B 5/7475 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 23/28 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265195 | Mooney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dephy, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dephy, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Luke Mooney (Westford, Massachusetts); Jean-Francois Duval (Malden, Massachusetts) |
| ABSTRACT | The present invention is directed to an autonomous exoskeleton device that includes one or more actuators, one or more controllers, one or more sensors with one or more unidirectional transmissions. The present invention provides a mechanical joint in parallel with a biological joint. The exoskeleton device preferably includes and electric motor and winch, chain, belt, cam transmission or other mechanism for providing unidirectional force to assist rotation about the biologic joint. Moreover, a controller, a motor angle sensor, joint angle sensor and/or force sensor may be used for additional control and monitoring of the device. The motor may be any type of motor, but is preferably brushless in configuration where its diameter is larger than its length to provide a compact and lightweight exoskeleton device. |
| FILED | Thursday, October 12, 2017 |
| APPL NO | 15/782306 |
| ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4528 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/70 (20130101) A61F 2/6607 (20130101) Original (OR) Class A61F 5/01 (20130101) A61F 2002/503 (20130101) A61F 2002/607 (20130101) A61F 2002/701 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) A61H 2201/5058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265315 | O'Malley et al. |
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| FUNDED BY |
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| APPLICANT(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| ASSIGNEE(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | Bert W. O'Malley (Houston, Texas); David Michael Lonard (Pearland, Texas); Jin Wang (Sugar Land, Texas); Jianming Xu (Bellaire, Texas); Jianwei Chen (Houston, Texas) |
| ABSTRACT | Small molecule regulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing SRC-related diseases. The SRC-related diseases can include cancer, metabolic disorders, human immunodeficiency virus, neurodegenerative disorders, and/or inflammatory diseases. Also provided are methods for regulating SRC family proteins in a cell. |
| FILED | Thursday, April 06, 2017 |
| APPL NO | 15/480731 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4402 (20130101) Heterocyclic Compounds C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 409/12 (20130101) C07D 413/12 (20130101) C07D 417/12 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 498/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265694 | Aizenberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Joanna Aizenberg (Boston, Massachusetts); Tanya Shirman (Arlington, Massachusetts); Nicolas Vogel (Cambridge, Massachusetts); Mathias Kolle (Somerville, Massachusetts); Michael Aizenberg (Boston, Massachusetts) |
| ABSTRACT | Methods for forming an interconnected network of solid material and pores, with metal residing only at the air/solid interface of the interconnected network structure are described. In certain embodiments, nanoparticle decorated sacrificial particles can be used as sacrificial templates for the formation of a porous structure having an interconnected network of solid material and interconnected network of pores. The nanoparticles reside predominantly at the air/solid interface and allow further growth and accessibility of the nanoparticles at defined positions of the interconnected structure. SEM and TEM measurements reveal the formation of 3D interconnected porous structures with nanoparticles residing predominantly at the air/solid interface of the interconnected structure. |
| FILED | Monday, June 30, 2014 |
| APPL NO | 14/900567 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/52 (20130101) B01J 35/10 (20130101) Original (OR) Class B01J 37/0018 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/01 (20130101) C04B 38/06 (20130101) C04B 38/0074 (20130101) C04B 38/0096 (20130101) C04B 38/0096 (20130101) C04B 2111/0081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266251 | Balsiger et al. |
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| FUNDED BY |
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| APPLICANT(S) | HAMILTON SUNDSTRAND CORPORATION (Windsor Locks, Connecticut) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Windsor Locks, Connecticut) |
| INVENTOR(S) | Derick S. Balsiger (Mayer, Arizona); Parag M. Kshirsagar (South Windsor, Connecticut); Xin Wu (Glastonbury, Connecticut) |
| ABSTRACT | An electromechanical actuator includes a ground arm, an output arm rotatable about an axis of rotation relative to the ground arm and a position sensing arrangement to determine an angular position of the output arm relative to the ground arm. The position sensing arrangement includes a position sensor fixed at the ground arm. The position sensor is configured to sense magnetic reluctance. A sensed portion is located at the output arm proximate to the position sensor. The sensed portion includes a geometric variation in an output arm surface configured to vary a magnetic reluctance sensed at the position sensor as a function of angular position of the output arm relative to the ground arm. |
| FILED | Tuesday, January 12, 2016 |
| APPL NO | 14/993730 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 13/28 (20130101) Original (OR) Class Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/145 (20130101) G01D 5/147 (20130101) G01D 5/2013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266258 | Keennon et al. |
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| FUNDED BY |
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| APPLICANT(S) | AeroVironment, Inc. (Monrovia, California) |
| ASSIGNEE(S) | AEROVIRONMENT, INC. (Monrovia, California) |
| INVENTOR(S) | Matthew Todd Keennon (Simi Valley, California); Karl Robert Klingebiel (Simi Valley, California); Alexander Andryukov (Simi Valley, California); Bart Dean Hibbs (Simi Valley, California); John Peter Zwaan (Simi Valley, California) |
| ABSTRACT | Heavier-than-air, aircraft having flapping wings, e.g., ornithopters, where angular orientation control is effected by variable differential sweep angles of deflection of the flappable wings in the course of sweep angles of travel and/or the control of variable wing membrane tension. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 15/923878 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 19/00 (20130101) B64C 33/02 (20130101) B64C 33/025 (20130101) Original (OR) Class B64C 2201/10 (20130101) B64C 2201/025 (20130101) B64C 2201/146 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266284 | Coffey et al. |
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| FUNDED BY |
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| APPLICANT(S) | Shannon Coffey (Springfield, Virginia); Joseph A. Carroll (Chula Vista, California); Paul Oppenheimer (Edgewater, Maryland); Jordan R. Schlater (Rossburg, Ohio); Ivan Galysh (Chantilly, Virginia); Eugene Levin (Minnetonka, Minnesota); Curt Hogan (Napoleon, Ohio); Adam Thurn (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Shannon Coffey (Springfield, Virginia); Joseph A. Carroll (Chula Vista, California); Paul Oppenheimer (Edgewater, Maryland); Jordan R. Schlater (Rossburg, Ohio); Ivan Galysh (Chantilly, Virginia); Eugene Levin (Minnetonka, Minnesota); Curt Hogan (Napoleon, Ohio); Adam Thurn (Washington, District of Columbia) |
| ABSTRACT | A tethered spacecraft has a first endmass and a second endmass with a telescoping stacer spring and a tether arranged between the endmasses. The spring is coiled around a center rod and initially contained within a housing, the spring being biased to push the first endmass away from the second endmass. The spring housing is affixed to the first endmass, a first end of the spring being affixed to the spring housing, and tether are affixed to spring at one end and to the second endmass at the other end. A pretensioned loop holds the endmasses abuttingly together, and a burnwire release mechanism cuts the loop to deploy the spring. Upon deployment, the spring extends to its full length to form a cylindrical boom, and the endmasses continue to move outward along the spring centerline until stopped by the tether. |
| FILED | Saturday, March 29, 2014 |
| APPL NO | 14/229905 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Perforating; Punching; Cutting-out; Stamping-out; Severing by Means Other Than Cutting B26F 3/12 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/36 (20130101) B64G 1/40 (20130101) B64G 1/44 (20130101) B64G 1/66 (20130101) B64G 1/363 (20130101) B64G 1/366 (20130101) B64G 1/645 (20130101) B64G 1/648 (20130101) Original (OR) Class B64G 1/1021 (20130101) Technical Subjects Covered by Former US Classification Y10T 83/293 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266392 | Najafi et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); E-PACK, INC. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | E-PACK, INC. (Ann Arbor, Michigan); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Khalil Najafi (Ann Arbor, Michigan); Sang-Hyun Lee (Ann Arbor, Michigan); Sang Woo Lee (Ann Arbor, Michigan); Jay Stewart Mitchell (Ypsilanti, Michigan); Onnop Srivannavit (Ann Arbor, Michigan) |
| ABSTRACT | An environment-resistant module which provides both thermal and vibration isolation for a packaged micromachined or MEMS device is disclosed. A microplatform and a support structure for the microplatform provide the thermal and vibration isolation. The package is both hermetic and vacuum compatible and provides vertical feedthroughs for signal transfer. A micromachined or MEMS device transfer method is also disclosed that can handle a wide variety of individual micromachined or MEMS dies or wafers, in either a hybrid or integrated fashion. The module simultaneously provides both thermal and vibration isolation for the MEMS device using the microplatform and the support structure which may be fabricated from a thin glass wafer that is patterned to create crab-leg shaped suspension tethers or beams. |
| FILED | Monday, April 14, 2014 |
| APPL NO | 14/251972 |
| ART UNIT | 2896 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/0058 (20130101) Original (OR) Class B81B 7/0064 (20130101) B81B 2201/0235 (20130101) B81B 2201/0242 (20130101) B81B 2201/0278 (20130101) B81B 2207/07 (20130101) B81B 2207/096 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 3/005 (20130101) B81C 2203/031 (20130101) B81C 2203/035 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2224/16225 (20130101) H01L 2924/00 (20130101) H01L 2924/1461 (20130101) H01L 2924/1461 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266398 | Kubena et al. |
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| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Randall L. Kubena (Oak Park, California); Richard J. Joyce (Thousand Oaks, California) |
| ABSTRACT | A method for fabricating a Microelectromechanical System (MEMS) resonator includes providing a dielectric substrate defining a resonator and depositing a conductive coating having a resistivity of approximately 1 to 50 μΩ-cm on that substrate by Atomic Layer Deposition (ALD). A resonator fabricated according to this process includes a dielectric substrate defining a resonator and a conductive coating having a resistivity of approximately 1 to 50 μΩ-cm for electrically coupling the resonator to electronics. Another method for fabricating a MEMS resonator includes providing a dielectric substrate defining a resonator, depositing an aluminum oxide film on that substrate by ALD, and depositing a noble metal film on the aluminum oxide film, also by ALD. |
| FILED | Wednesday, November 26, 2014 |
| APPL NO | 14/555459 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00206 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/06 (20130101) C23C 16/45525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266549 | Shaw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California); SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California); YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California); SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California); YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Reuben J. Shaw (La Jolla, California); Daniel F. Egan (La Jolla, California); Nicholas Cosford (La Jolla, California); Benjamin Turk (New Haven, Connecticut); Mitchell Vamos (La Jolla, California); Dhanya Raveendra Panickar (La Jolla, California); Matthew Chun (La Jolla, California); Douglas Sheffler (La Jolla, California) |
| ABSTRACT | In certain aspects, the invention provides a method for treating a disease or condition in a subject, the method comprising co-administering to a subject in need thereof a therapeutically effective amount of at least one ULK1-inhibiting pyrimidine, and a therapeutically effective amount of an mTOR inhibitor. |
| FILED | Tuesday, August 25, 2015 |
| APPL NO | 15/505532 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/5377 (20130101) A61K 31/5383 (20130101) A61K 31/5383 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 239/34 (20130101) C07D 239/42 (20130101) C07D 239/47 (20130101) C07D 239/48 (20130101) C07D 239/557 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 413/14 (20130101) C07D 417/04 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) C07D 471/04 (20130101) C07D 498/04 (20130101) Original (OR) Class Peptides C07K 7/08 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Enzymes C12Y 207/11001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/912 (20130101) G01N 2500/04 (20130101) G01N 2500/20 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266702 | Curran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Seamus Curran (Pearland, Texas); Kang-Shyang Liao (Houston, Texas); Killian Barton (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Seamus Curran (Pearland, Texas); Kang-Shyang Liao (Houston, Texas); Killian Barton (Houston, Texas) |
| ABSTRACT | A method of forming a self-cleaning coating on a substrate comprises the step of selecting a substrate, cleaning the substrate, and/or roughening the substrate using an abrasive. In an embodiment, roughening of the substrate create microscopic tortuous grooves. Another embodiment of the method comprises coating the roughened surface with at least one hydrophobic chemical agent. In an exemplary embodiment, the hydrophobic chemical agent covalently binds with the substrate creating nanoscopic grooves. Another embodiment of the present disclosure pertains to an apparatus for depositing a self-cleaning coating on a flat substrate. A further embodiment of the present disclosure pertains to a self-cleaning coating on a substrate comprising a hydrophobic chemical agent covalently bonded to at least one roughened surface of the substrate. |
| FILED | Monday, June 10, 2013 |
| APPL NO | 13/913728 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/02 (20130101) B05D 3/12 (20130101) B05D 3/142 (20130101) B05D 5/02 (20130101) B05D 5/083 (20130101) B05D 2203/35 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 17/30 (20130101) C03C 2217/76 (20130101) C03C 2218/31 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/00 (20130101) Original (OR) Class C09D 5/1625 (20130101) C09D 5/1681 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/10 (20141201) Technical Subjects Covered by Former US Classification Y10T 428/265 (20150115) Y10T 428/24355 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266765 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Wei Chen (Arlington, Texas); Lun Ma (Arlington, Texas) |
| ABSTRACT | This invention relates to new phosphor materials exhibiting luminescence and methods for their production. More particularly, the invention relates to new europium-doped zinc sulfide-manganese (ZnS:Mn,Eu) phosphors and use thereof for radiation detection. |
| FILED | Thursday, November 06, 2014 |
| APPL NO | 15/034124 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/773 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266815 | Siegel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington Through Its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Justin Bloomfield Siegel (Seattle, Washington); David Baker (Seattle, Washington); Ingrid Swanson Pultz (Seattle, Washington) |
| ABSTRACT | The invention provides compositions and methods for treating celiac sprue. |
| FILED | Wednesday, August 13, 2014 |
| APPL NO | 14/911630 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class C12N 9/6489 (20130101) Enzymes C12Y 304/21048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266886 | Abudayyeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTED OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Omar Abudayyeh (Cambridge, Massachusetts); James Joseph Collins (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Feng Zhang (Cambridge, Massachusetts); Eric S. Lander (Cambridge, Massachusetts) |
| ABSTRACT | The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/917546 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6811 (20130101) C12Q 1/6816 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/51 (20180101) Y02A 50/53 (20180101) Y02A 50/58 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266887 | Abudayyeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Omar Abudayyeh (Cambridge, Massachusetts); James Joseph Collins (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Feng Zhang (Cambridge, Massachusetts); Eric S. Lander (Cambridge, Massachusetts) |
| ABSTRACT | The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/917549 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6811 (20130101) C12Q 1/6816 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/51 (20180101) Y02A 50/53 (20180101) Y02A 50/58 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266936 | Potrepka et al. |
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| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Daniel M. Potrepka (Silver Spring, Maryland); James R. Mulcahy (Bowie, Maryland); Ronald G. Polcawich (Derwood, Maryland) |
| ABSTRACT | A method of making a piezoelectric device comprising providing a deposition chamber, the deposition chamber having reduced pressure therein; loading a substrate into the deposition chamber; sputter depositing hexagonal 001 oriented titanium on the substrate; providing an oxygen anneal to convert 001 oriented titanium into 100 oriented rutile TiO2; sputter depositing a 111 or 100 oriented textured conducting material for use as an electrode; sputter depositing a hexagonal 001 oriented titanium and providing an oxygen anneal in a lead oxide environment to convert 001 oriented titanium into 100 oriented rutile TiO2 or PbxTi1-xO3; sputter depositing textured lead zirconate titanate PbZrxTi1-xO3 having an 001 orientation as a piezoelectric layer, and sputter depositing a textured electrode on top of the textured lead zirconate titanate; whereby processing of the layers within the deposition chamber provides minimized exposure to ambient contamination and improved texturing in the resulting films. |
| FILED | Friday, March 04, 2016 |
| APPL NO | 15/061205 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/088 (20130101) Original (OR) Class C23C 14/185 (20130101) C23C 14/5853 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 1/02 (20130101) C30B 1/10 (20130101) C30B 23/025 (20130101) C30B 25/183 (20130101) C30B 29/02 (20130101) C30B 29/16 (20130101) C30B 29/32 (20130101) C30B 29/68 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/27 (20130101) H01L 41/316 (20130101) H01L 41/319 (20130101) H01L 41/0815 (20130101) H01L 41/1876 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266963 | Nepal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Neeraj Nepal (Woodbridge, Virginia); Virginia D. Wheeler (Alexandria, Virginia); Charles R. Eddy, Jr. (Columbia, Maryland); Francis J. Kub (Arnold, Maryland); Travis J. Anderson (Alexandria, Virginia); Michael A. Mastro (Fairfax, Virginia); Rachael L. Myers-Ward (Springfield, Virginia); Sandra C. Hangarter (Gaithersburg, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Neeraj Nepal (Woodbridge, Virginia); Virginia D. Wheeler (Alexandria, Virginia); Charles R. Eddy, Jr. (Columbia, Maryland); Francis J. Kub (Arnold, Maryland); Travis J. Anderson (Alexandria, Virginia); Michael A. Mastro (Fairfax, Virginia); Rachael L. Myers-Ward (Springfield, Virginia); Sandra C. Hangarter (Gaithersburg, Maryland) |
| ABSTRACT | A method of growing crystalline materials on two-dimensional inert materials comprising functionalizing a surface of a two-dimensional inert material, growing a nucleation layer on the functionalized surface, and growing a crystalline material. A crystalline material grown on a two-dimensional inert material made from the process comprising functionalizing a surface of a two-dimensional inert material, growing a nucleation layer on the functionalized surface, and growing a crystalline material. |
| FILED | Thursday, January 30, 2014 |
| APPL NO | 14/168517 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/183 (20130101) C30B 25/186 (20130101) Original (OR) Class C30B 29/40 (20130101) C30B 29/48 (20130101) C30B 29/406 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267152 | Wasserman et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | David J. Wasserman (Hamden, Connecticut); Ronald R. Gagnon, Jr. (Tolland, Connecticut); Christopher M. Juh (South Windsor, Connecticut); Larry A. Witherup (Manchester, Connecticut); David B. Hudson (Tequesta, Florida) |
| ABSTRACT | The present application relates generally to a piloted nut. The piloted nut may be used on a tie-shaft to apply an axial load to a rotor. A piloting feature on an exterior surface of the nut provides radial piloting to the rotor. The piloted nut may be used in a gas turbine engine to apply an axial load to a rotor. |
| FILED | Friday, September 12, 2014 |
| APPL NO | 14/485057 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/025 (20130101) Original (OR) Class F01D 5/066 (20130101) Non-positive-displacement Pumps F04D 29/263 (20130101) F04D 29/266 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2260/301 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/31 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 37/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267567 | Ndao et al. |
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| FUNDED BY |
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| APPLICANT(S) | NuTech Ventures, Inc. (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Sidy Ndao (Lincoln, Nebraska); George Gogos (Lincoln, Nebraska); Dennis Alexander (Lincoln, Nebraska); Troy Anderson (Omaha, Nebraska); Craig Zuhlke (Lincoln, Nebraska) |
| ABSTRACT | A monolithic heat-transfer device can include a container wall configured to retain a working fluid, where the container wall is formed of a single material. The container wall also includes an interior surface configured to be in fluid communication with the working fluid. The monolithic heat-transfer device also includes a channel disposed in the interior surface of the container wall, where the channel comprises a microstructure and a nanostructure. The microstructure and the nanostructure are materially contiguous with the single material forming the container wall. In some embodiments, the nanostructure comprises one or more layers of nanoparticles. The monolithic heat-transfer device can be configured as a heat pipe, which can be constructed from the container wall and a second container wall joined together and sealed to one another to contain the working fluid (e.g., using laser welding, electron beam welding (EBW), and so forth). |
| FILED | Tuesday, January 13, 2015 |
| APPL NO | 14/595516 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267582 | Englert |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Stefan L. Englert (Temecula, California) |
| ABSTRACT | A system, device, and method for measuring the temperature of a chambered projectile within a firearm are provided. A test ammunition round may include a projectile, a sleeve, and a case including a first end coupled to sleeve, and a second end coupled to the projectile. A thermocouple may be located within the projectile, and an electronic coupler may be coupled to the thermocouple, and extends through the case and the sleeve and exits the sleeve through a slot for coupling to a data acquisition system. |
| FILED | Wednesday, April 01, 2015 |
| APPL NO | 14/676793 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 13/00 (20130101) Original (OR) Class F41A 31/00 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/24 (20130101) F42B 8/02 (20130101) F42B 8/08 (20130101) F42B 12/365 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 1/026 (20130101) G01K 7/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49119 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267603 | Marshall et al. |
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| FUNDED BY |
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| APPLICANT(S) | Southwest Research Institute (San Antonio, Texas) |
| ASSIGNEE(S) | SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas) |
| INVENTOR(S) | Andrew J. Marshall (San Antonio, Texas); Thad C. Smith (College Station, Texas); Carl E. Weiss (San Antonio, Texas); Joseph M. Herring (San Antonio, Texas) |
| ABSTRACT | One embodiment provides an apparatus. The apparatus includes a substrate body that includes a top end, an opposing bottom end and a curved outer surface positioned there between, and a clear sight bore aperture centered at a longitudinal axis of the substrate body. The apparatus further includes a trunk line aperture defined in the outer surface of the substrate body. The trunk line aperture has a first end positioned at a top end of the substrate body, off-center from the longitudinal axis. The first end of the trunk line aperture is configured to couple to a detonator. The apparatus further includes a plurality of helical track apertures defined in the outer surface of the substrate body. A respective first end of each helical track aperture is coupled to the trunk line aperture. The apparatus further includes a plurality of termination apertures defined in the outer surface of the substrate body adjacent the bottom end of the substrate body. One termination aperture is coupled to the trunk line aperture at a second end of the trunk line aperture. The second end is opposing the first end and each remaining termination aperture is coupled to a respective helical track aperture. The trunk line aperture, the plurality of helical track apertures and the plurality of termination apertures are configured to contain an explosive material. |
| FILED | Tuesday, July 25, 2017 |
| APPL NO | 15/659422 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 1/028 (20130101) Original (OR) Class Blasting F42D 1/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267608 | Gupta et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | Washington State University (Pullman, Washington) |
| INVENTOR(S) | Yogendra M. Gupta (Spokane, Washington); Atakan Peker (Spokane, Washington) |
| ABSTRACT | Munitions structures comprising one or more high strength reactive alloys, in particular reactive bulk metallic glasses, have significant amounts of inherent chemical energy. This energy may be discharged by subjection of the munitions structure to rapid impulsive loading and fragmentation in the presence of oxygen and/or nitrogen. A munitions structure can be configured in both large and small penetrators, e.g. warheads and bullets, with increased lethality. The lethality of these munitions structures is augmented by means of rapidly and simultaneously imparting both mechanical energy (kinetic energy through impact and fragmentation) and chemical energy (blast and/or fireball) to a target. A high-strength reactive alloy can substitute at least in part one or both of explosives and inert structural materials in conventional munitions systems to improve performance and reduce parasitic weight of structural casing. |
| FILED | Wednesday, June 07, 2017 |
| APPL NO | 15/616849 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Alloys C22C 1/02 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/74 (20130101) F42B 12/207 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267684 | Barnard |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth J. Barnard (Fairborn, Ohio) |
| ABSTRACT | An apparatus, system, and method to characterize a focal plane array. The apparatus includes a speckle field source to generate and emit a plurality of uniform speckle fields, a diamond-shape aperture, and a pedestal to mount the focal plane array at a predetermined distance from the aperture. The diamond-shape aperture shapes the uniform speckle fields from the speckle field source so that the uniform speckle fields have a desired power spectral density at the focal plane array. The desired power spectral density has recoverable aliased regions out to two times the Nyquist frequency of the focal plane array. The system includes a controller to characterize, by computing a modulation transfer function, the focal plane array based on the desired power spectral density of the uniform speckle fields impinging on the focal plane array. |
| FILED | Tuesday, February 06, 2018 |
| APPL NO | 15/889939 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/026 (20130101) Original (OR) Class G01J 5/522 (20130101) G01J 2005/0048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267690 | Wu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Xin Alice Wu (Stanford, California); John V Ulmen (Redwood City, California); Mark R. Cutkosky (Palo Alto, California) |
| ABSTRACT | A capacitive force sensor is provided that includes a first support layer and a second support layer, a dielectric layer disposed between the first support layer and the second support layer, where the dielectric layer is a non-conductive elastomer that is incompressible in the a normal direction and deflects in a shear direction, a layer of parallel conductive traces disposed between and bonded to the dielectric layer and the first support layer, and a conductive layer of parallel shear channel traces having at least two distinct channels disposed between and bonded to the dielectric layer and the second support layer, where the parallel conductive traces and the parallel shear channel traces are locally parallel to each other and provide capacitive shear force measurement sensitivity while rejecting normal forces, where the normal force measurement is decoupled from the shear force measurement. |
| FILED | Wednesday, September 13, 2017 |
| APPL NO | 15/703122 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 13/082 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/142 (20130101) G01L 1/146 (20130101) Original (OR) Class G01L 5/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267802 | Berek et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Standord, California) |
| INVENTOR(S) | Jonathan Berek (Stanford, California); Wendy Fantl (San Francisco, California); Veronica Gonzalez (Stanford, California); Garry P. Nolan (San Francisco, California); Nikolay Samusik (Palo Alto, California) |
| ABSTRACT | Cellular markers indicating a poor prognosis for ovarian cancer patients are disclosed. In particular, the invention relates to methods utilizing the frequency of a subset of cells in ovarian tumor tissue expressing vimentin, cMyc, or HE4, or any combination thereof, to predict an ovarian cancer patient will relapse. |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/275043 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57449 (20130101) Original (OR) Class G01N 2333/4703 (20130101) G01N 2800/52 (20130101) G01N 2800/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267891 | Webber et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Frederick Webber (Xenia, Ohio); Eric Vinande (Centerville, Ohio) |
| ABSTRACT | A system and method for transferring data includes an information platform to identify a navigational position of the information platform; a first near field communication (NFC) device attached to the information platform to transmit navigational position data; and a second NFC device to receive the navigational position data from the first NFC device through a NFC data transfer process to establish a navigational position of the second NFC device relative to the first NFC device and without further communication from the first NFC device. The information platform may be stationary. The information platform may be moving. The information platform may include any of a global navigation satellite system (GNSS) platform, an inertial navigation system, and a cell phone. The NFC data transfer process may occur within one second. |
| FILED | Friday, April 20, 2018 |
| APPL NO | 15/958371 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0072 (20130101) Original (OR) Class Transmission H04B 5/0031 (20130101) Wireless Communication Networks H04W 4/80 (20180201) H04W 64/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267956 | Arbabi et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Ehsan Arbabi (Pasadena, California); Amir Arbabi (Pasadena, California); Andrei Faraon (La Canada Flintridge, California) |
| ABSTRACT | Structures for scattering light at multiple wavelengths are disclosed. Scattering elements are fabricated with different geometric dimensions and arrangements, to scatter or focus light at the same focal distance for each wavelength, or at different focal distances according to the desired application. Scattering elements can be circular or elliptical posts, allowing polarization dependent scattering. The elements can have different orientations to scatter light from multiple wavelengths at the desired focal length. |
| FILED | Tuesday, April 12, 2016 |
| APPL NO | 15/096615 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/0226 (20130101) Original (OR) Class G02B 5/0263 (20130101) G02B 5/0268 (20130101) G02B 5/1876 (20130101) G02B 27/0025 (20130101) G02B 27/4211 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267957 | Kamali et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Seyedeh Mahsa Kamali (Pasadena, California); Ehsan Arbabi (Pasadena, California); Amir Arbabi (Pasadena, California); Andrei Faraon (La Canada Flintridge, California) |
| ABSTRACT | Structures for scattering light at multiple wavelengths are disclosed. Scattering elements are fabricated with different geometric dimensions and arrangements, to scatter or focus light at the same focal distance for each wavelength, or at different focal distances according to the desired application. The scattering elements fabricated on a substrate can be peeled off with a polymer matrix and attached to a lens to modify the optical properties of the lens. |
| FILED | Wednesday, May 09, 2018 |
| APPL NO | 15/975521 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/0226 (20130101) Original (OR) Class G02B 5/0242 (20130101) G02B 5/0263 (20130101) G02B 5/0268 (20130101) G02B 5/0278 (20130101) G02B 5/1876 (20130101) G02B 27/0025 (20130101) G02B 27/4211 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268232 | Harris et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Nicholas Christopher Harris (Cambridge, Massachusetts); Jacques Johannes Carolan (Somerville, Massachusetts); Mihika Prabhu (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts); Scott A. Skirlo (Beavercreek, Ohio); Yichen Shen (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
| ABSTRACT | An optical neural network is constructed based on photonic integrated circuits to perform neuromorphic computing. In the optical neural network, matrix multiplication is implemented using one or more optical interference units, which can apply an arbitrary weighting matrix multiplication to an array of input optical signals. Nonlinear activation is realized by an optical nonlinearity unit, which can be based on nonlinear optical effects, such as saturable absorption. These calculations are implemented optically, thereby resulting in high calculation speeds and low power consumption in the optical neural network. |
| FILED | Friday, June 02, 2017 |
| APPL NO | 15/612043 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/225 (20130101) G02F 1/365 (20130101) G02F 1/3526 (20130101) G02F 3/024 (20130101) G02F 2001/212 (20130101) G02F 2202/32 (20130101) G02F 2203/15 (20130101) Optical Computing Devices; G06E 3/005 (20130101) Original (OR) Class G06E 3/006 (20130101) G06E 3/008 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268601 | Okhravi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Hamed Okhravi (Billerica, Massachusetts); Thomas R. Hobson (Belmont, Massachusetts); David O. Bigelow (Maynard, Massachusetts); Robert Rudd (Cambridge, Massachusetts); David M. Perry (Eddyville, Kentucky); Kristin S. Dahl (Cambridge, Massachusetts); William W. Streilein (Sudbury, Massachusetts) |
| ABSTRACT | In a system executing a program, a method comprises detecting one or more input/output calls associated with the program and re-randomizing memory associated with the program in response to the one or more input/output calls. A related system is also described. |
| FILED | Friday, June 17, 2016 |
| APPL NO | 15/185370 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1004 (20130101) G06F 12/1466 (20130101) Original (OR) Class G06F 21/52 (20130101) G06F 2212/402 (20130101) G06F 2212/1052 (20130101) G06F 2221/033 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0894 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268783 | Helber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert W. Helber (Slidell, Louisiana); Scott R. Smith (Slidell, Louisiana); Gregg Arthur Jacobs (Slidell, Louisiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Robert W. Helber (Slidell, Louisiana); Scott R. Smith (Slidell, Louisiana); Gregg Arthur Jacobs (Slidell, Louisiana) |
| ABSTRACT | System and method for correcting the vertical structure of the ocean temperature and salinity can enable the use of sea surface height (SSH) measurements to correct ocean forecast models. In the present embodiment, three relations that can be precomputed are exploited: (1) the relation between temperature and salinity throughout a water column, (2) the relation between temperature/salinity and geopotential, and (3) the relation between geopotential and SSH. The relations are stored in a form that allows efficient application through a cross-correlation matrix. |
| FILED | Thursday, October 23, 2014 |
| APPL NO | 14/522570 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 11/00 (20130101) Meteorology G01W 1/10 (20130101) Electric Digital Data Processing G06F 17/16 (20130101) G06F 17/5009 (20130101) Original (OR) Class G06F 2217/16 (20130101) Technologies for Adaptation to Climate Change Y02A 90/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268900 | Divakaran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Ajay Divakaran (Monmouth Junction, New Jersey); Qian Yu (Plainsboro, New Jersey); Amir Tamrakar (Philadelphia, Pennsylvania); Harpreet Singh Sawhney (Princeton Junction, New Jersey); Jiejie Zhu (East Windsor, New Jersey); Omar Javed (Franklin Park, New Jersey); Jingen Liu (Plainsboro, New Jersey); Hui Cheng (Bridgewater, New Jersey); Jayakrishnan Eledath (Robbinsville, New Jersey) |
| ABSTRACT | A system for object detection and tracking includes technologies to, among other things, detect and track moving objects, such as pedestrians and/or vehicles, in a real-world environment, handle static and dynamic occlusions, and continue tracking moving objects across the fields of view of multiple different cameras. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 15/905937 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00771 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268931 | Shafer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Scott Allen Shafer (San Diego, California); Pedro Andres Forero (San Diego, California); Joshua David Harguess (San Diego, California) |
| ABSTRACT | A method for constructing a dictionary to represent data from a training data set comprising: modeling the data as a linear combination of columns; modeling outliers in the data set via deterministic outlier vectors; formatting the training data set in matrix form for processing; defining an underlying structure in the data set; quantifying a similarity across the data; building a Laplacian matrix; using group-Lasso regularizers to succinctly represent the data; choosing scalar parameters for controlling the number of dictionary columns used to represent the data and the number of elements of the training data set identified as outliers; using BCD and PG methods on the vector-matrix-formatted data set to estimate a dictionary, corresponding expansion coefficients, and the outlier vectors; and using a length of the outlier vectors to identify outliers in the data. |
| FILED | Wednesday, March 29, 2017 |
| APPL NO | 15/472833 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 17/2735 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) Original (OR) Class G06K 9/6296 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/063 (20130101) G10L 2015/0631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10269504 | Ervin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Matthew H. Ervin (Clarksville, Maryland) |
| ABSTRACT | A supercapacitor or electrochemical capacitor includes spaced apart electrodes which are separated from each other by a separator made of an electrically insulating material. Each electrode is formed of carbonaceous material and capable of being impregnated with a liquid electrolyte. Metal current collectors are provided on the sides of the electrodes opposite from the separator. The electrodes have holes or elongated orifices extending through the electrodes to reduce ionic impedance in order to produce faster charging and discharging of the device. |
| FILED | Thursday, May 19, 2016 |
| APPL NO | 15/159401 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) Original (OR) Class H01G 11/26 (20130101) H01G 11/28 (20130101) H01G 11/32 (20130101) H01G 11/36 (20130101) H01G 11/38 (20130101) H01G 11/52 (20130101) H01G 11/66 (20130101) H01G 11/86 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10269525 | Marcus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CLEMSON UNIVERSITY (Clemson, South Carolina); Lawrence Berkeley National Laboratory (Berkeley, California); Pacific Northwest National Laboratory (Richland, Washington) |
| ASSIGNEE(S) | Clemson University Research Foundation (Clemson, South Carolina); Battelle Memorial Institute on behalf of Pacific Northwest National Laboratory (Richland, Washington); The Regents of the University of California Lawrence Berkeley National Laboratory (Berkeley, California) |
| INVENTOR(S) | R. Kenneth Marcus (Clemson, South Carolina); Charles Derrick Quarles, Jr. (San Jose, California); Richard E. Russo (Berkeley, California); David W. Koppenaal (Richland, Washington); Charles J. Barinaga (Richland, Washington); Anthony J. Carado (Richland, Washington) |
| ABSTRACT | A liquid sampling, atmospheric pressure, glow discharge (LS-APGD) device as well as systems that incorporate the device and methods for using the device and systems are described. The LS-APGD includes a hollow capillary for delivering an electrolyte solution to a glow discharge space. The device also includes a counter electrode in the form of a second hollow capillary that can deliver the analyte into the glow discharge space. A voltage across the electrolyte solution and the counter electrode creates the microplasma within the glow discharge space that interacts with the analyte to move it to a higher energy state (vaporization, excitation, and/or ionization of the analyte). |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/359969 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/443 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 27/16 (20130101) H01J 27/022 (20130101) Original (OR) Class H01J 49/105 (20130101) H01J 49/145 (20130101) H01J 49/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10269580 | Armstrong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Christine Armstrong (Stamford, New York); Matthew W. Copel (Yorktown Heights, New York); Yu Luo (Hopewell Junction, New York); Paul M. Solomon (Yorktown Heights, New York) |
| ABSTRACT | A subtractive forming method that includes providing a material stack including a samarium and selenium containing layer and an aluminum containing layer in direct contact with the samarium and selenium containing layer. The samarium component of the samarium and selenium containing layer of the exposed portion of the material stack is etched with an etch chemistry comprising citric acid and hydrogen peroxide that is selective to the aluminum containing layer. The hydrogen peroxide reacts with the aluminum containing layer to provide an oxide etch protectant surface on the aluminum containing layer, and the citric acid etches samarium selectively to the oxide etch protectant surface. Thereafter, a remaining selenium component of is removed by elevating a temperature of the selenium component. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804394 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0256 (20130101) H01L 21/0262 (20130101) H01L 21/32134 (20130101) Original (OR) Class H01L 41/16 (20130101) H01L 41/39 (20130101) H01L 41/187 (20130101) H01L 41/316 (20130101) H01L 41/332 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10269989 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Fan Ren (Gainesville, Florida); Stephen J. Pearton (Gainesville, Florida); Soohwan Jang (Gainesville, Florida); Sunwoo Jung (Suwon-si, South Korea) |
| ABSTRACT | A hydrogen sensor can include a substrate, an Ohmic metal disposed on the substrate, a nitride layer disposed on the substrate and having a first window exposing the substrate, a Schottky metal placed in the first window and disposed on the substrate, a final metal disposed on the nitride layer and the Schottky metal and having a second window exposing the Schottky metal, and a polymethyl-methacrylate (PMMA) layer encapsulating the second window. The PMMA layer can fill the second window and be in contact with the Schottky metal. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 15/906701 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/129 (20130101) G01N 27/4074 (20130101) G01N 33/005 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0495 (20130101) H01L 23/291 (20130101) H01L 23/293 (20130101) H01L 23/3171 (20130101) H01L 23/3192 (20130101) H01L 29/47 (20130101) H01L 29/205 (20130101) H01L 29/475 (20130101) H01L 29/872 (20130101) Original (OR) Class H01L 29/2003 (20130101) H01L 29/66143 (20130101) H01L 29/66212 (20130101) H01L 29/66219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270480 | Guyette et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Andrew C. Guyette (San Mateo, California); Eric J. Naglich (Alexandria, Virginia) |
| ABSTRACT | Systems and methods are provided for implementing bandstop filters (e.g., RF/microwave bandstop filters) that can automatically tune to a frequency of an interfering signal. Embodiments of the present disclosure provide automatically tunable signal-tracking bandstop filters with a significant reduction in response time, complexity, size, weight, and cost when compared to conventional devices. |
| FILED | Friday, October 06, 2017 |
| APPL NO | 15/726579 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/12 (20130101) H03H 7/0153 (20130101) H03H 7/1741 (20130101) Tuning Resonant Circuits; Selecting Resonant Circuits H03J 3/06 (20130101) Transmission H04B 1/1036 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270529 | Karpov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (Lausanne, Switzerland) |
| ASSIGNEE(S) | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (Lausanne, Switzerland) |
| INVENTOR(S) | Maxim Karpov (Lausanne, Switzerland); Victor Brasch (Lausanne, Switzerland); Tobias Kippenberg (Lausanne, Switzerland) |
| ABSTRACT | A soliton generation apparatus comprising: an optical resonator; a pumping laser for providing light at a pumping wavelength into the optical resonator; a generator for generating multiple solitons in the optical resonator; a detuning device for changing the wavelength detuning between the pumping laser wavelength and an optical resonance wavelength of the optical resonator to remove at least one soliton of the generated multiple solitons to provide (i) a plurality of solitons that comprises at least one less soliton than that of the generated multiple solitons or (ii) a single soliton in the optical resonator. |
| FILED | Monday, January 16, 2017 |
| APPL NO | 15/406811 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/065 (20130101) G02F 1/073 (20130101) G02F 1/3513 (20130101) G02F 2203/26 (20130101) Transmission H04B 10/40 (20130101) H04B 10/50 (20130101) H04B 10/60 (20130101) H04B 10/508 (20130101) H04B 10/25077 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270547 | Pratt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Thomas G. Pratt (Niles, Michigan); Farzad Talebi (Mishawaka, Indiana) |
| ABSTRACT | A system and method for detection of complex sinusoidal signals. The method can include obtaining a set of complex-valued samples of one or more signals, in the presence of unknown noise, using a plurality of sensors. The presence of κ candidate complex sinusoids can be assumed. Then, κ candidate complex sinusoids in the set of complex-valued samples can be estimated. The method can include comparing a measurement of the energy of the κ estimated candidate complex sinusoids with a threshold value. Based on the comparison, a determination can be made whether to assume a different number of candidate complex sinusoids and repeat the estimation and the comparison steps, or to specify the estimated κ candidate complex sinusoids as detected complex sinusoids. The threshold value can be determined using a penalty value which reduces the probability of overestimating the number of complex sinusoids. |
| FILED | Monday, March 14, 2016 |
| APPL NO | 15/069819 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Transmission H04B 7/10 (20130101) H04B 7/0413 (20130101) H04B 17/336 (20150115) H04B 17/373 (20150115) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 27/34 (20130101) H04L 27/2636 (20130101) H04L 27/2649 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270665 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Leidos, Inc. (Reston, Virginia) |
| ASSIGNEE(S) | Leidos, Inc. (Reston, Virginia) |
| INVENTOR(S) | Ana M. Cheng (Odessa, Florida); Norbert J. Riviere (Seminole, Florida) |
| ABSTRACT | The invention provides a set of mechanisms by which a wireless mobile mesh node equipped with a directional antenna may self form and self adapt its steady-state communications schedule. A link establishment handshake is carried out over an ongoing subtemplate-based discovery scan. During time not reserved for steady-state communications with previously discovered neighbors, nodes continue to search for an establish links with new neighbors. Initial and subsequent bandwidth allocation protocols may be utilized to allow peer nodes to coordinate communication opportunities between the peer nodes without impacting or having knowledge about reservations for communications with other peers. The link establishment and initial bandwidth allocation protocols may be piggy-backed for readily establishing an initial steady-state schedule with a peer upon link establishment without impact on previous steady state reservations by other nodes or on ongoing link establishment attempts elsewhere. |
| FILED | Friday, January 19, 2018 |
| APPL NO | 15/875302 |
| ART UNIT | 2471 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/12 (20130101) Original (OR) Class Wireless Communication Networks H04W 72/044 (20130101) H04W 72/046 (20130101) H04W 72/0446 (20130101) H04W 72/0486 (20130101) H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270739 | Pal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
| INVENTOR(S) | Partha Pal (Boxborough, Massachusetts); Aaron Paulos (Somerville, Massachusetts); Richard E. Schantz (Sharon, Massachusetts) |
| ABSTRACT | A method for performing security functions in a computer system hosting a network-facing server application includes receiving, by a service request processor, a service request to an application adapted to process the service request; responsive to the service request being a first request for the application to communicate over a network, processing the service request with a first process isolated in memory from the application; responsive to the service request being a second request for the application to access a physical storage device, processing the service request with a second process isolated in memory from the application; and responsive to a determination that the processed service request will not adversely affect the application, providing the processed service request to the application. |
| FILED | Friday, August 04, 2017 |
| APPL NO | 15/668848 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/552 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0209 (20130101) Original (OR) Class H04L 63/0281 (20130101) H04L 63/1416 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270798 | Zaffarano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Siege Technologies LLC (Manchester, New Hampshire) |
| ASSIGNEE(S) | SIEGE TECHNOLOGIES LLC (Manchester, New Hampshire) |
| INVENTOR(S) | Kara Zaffarano (Rome, New York); Joshua Taylor (Rome, New York); Samuel Hamilton (Falls Church, Virginia) |
| ABSTRACT | A method for assessing effectiveness of one or more cybersecurity technologies in a computer network includes testing each of two or more component stages of an attack model at a first computer network element twice. A first one of the tests is conducted with a first one of the cybersecurity technologies operable to protect the first computer network element, and a second one of the tests is conducted with the first cybersecurity technology not operable to protect the first computer network element. For each one of the twice-tested component stages, comparing results from the first test and the second test, wherein the comparison yields or leads to information helpful in assessing effectiveness of the first cybersecurity technology on each respective one of the twice-tested component stages at the computer network element. |
| FILED | Thursday, October 06, 2016 |
| APPL NO | 15/286990 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/1433 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270803 | Gu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Guofei Gu (College Station, Texas); Phillip A. Porras (Cupertino, California); Martin W. Fong (Redwood City, California) |
| ABSTRACT | In one embodiment, the present invention is a method and apparatus for detecting malware infection. One embodiment of a method for detecting a malware infection at a local host in a network, includes monitoring communications between the local host and one or more entities external to the network, generating a dialog warning if the communications include a transaction indicative of a malware infection, declaring a malware infection if, within a predefined period of time, the dialog warnings includes at least one dialog warning indicating a transaction initiated at the local host and at least one dialog warning indicating an additional transaction indicative of a malware infection, and outputting an infection profile for the local host. |
| FILED | Wednesday, January 21, 2015 |
| APPL NO | 14/601969 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3495 (20130101) G06F 21/552 (20130101) G06F 21/564 (20130101) G06F 21/566 (20130101) G06F 21/577 (20130101) G06F 2221/2101 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/145 (20130101) Original (OR) Class H04L 63/1416 (20130101) H04L 63/1458 (20130101) H04L 2463/144 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10271273 | Cohen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Aaron E. Cohen (Alexandria, Virginia) |
| ABSTRACT | Systems and method are provided for dynamically adjusting relay methodology based on current radio frequency channel conditions by selecting an optimal relay method. Radio relay systems that can dynamically adapt their relay modes in accordance with embodiments of the present disclosure can achieve useful power savings over conventional relay systems designed for worst case scenario operation. |
| FILED | Saturday, April 29, 2017 |
| APPL NO | 15/582672 |
| ART UNIT | 2473 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 7/14 (20130101) H04B 7/15557 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/006 (20130101) Wireless Communication Networks H04W 52/0203 (20130101) Original (OR) Class Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 70/00 (20180101) Y02D 70/446 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10271402 | Cain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Anthony M. Cain (Beavercreek, Ohio); Danny J. Hugh (Fairborn, Ohio); Donald R. Thomas (Beavercreek, Ohio); Shawn R. Davidson (Xenia, Ohio) |
| ABSTRACT | A laser sensor stimulator integrates laser units, an inertial measurement unit, a control unit, and ergonomic, modular design with GPS data feeds into a portable system that can be used to test energy sensors and warning devices and includes a user interface facilitates tracking and acquisition of items of interest by the laser sensor stimulator. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/686638 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 21/00 (20130101) F21V 33/00 (20130101) Smallarms, e.g Pistols, Rifles; Accessories Therefor F41C 23/00 (20130101) Weapon Sights; Aiming F41G 1/00 (20130101) F41G 1/32 (20130101) F41G 1/54 (20130101) F41G 3/145 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 11/02 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 21/00 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 3/08 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4804 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 37/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10271437 | Pulskamp |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey Spencer Pulskamp (Fulton, Maryland) |
| ABSTRACT | A system for controlled motion of circuit components to create reconfigurable circuits comprising: a support; a substrate operatively associated with the support; actuators operatively associated with the support configured to physically move circuit components and to move the circuit components into physical and electrical contact with the substrate; the substrate comprising at least one conductive segment arranged to electrically connect circuit components when electrical contacts of circuit components are placed in contact with at least one conductive segment; and control circuitry configured to control the first and second actuators to thereby position the circuit components relative to the substrate; whereby circuit function is determined by the selection of circuit components and the location and orientation of circuit components relative to the substrate and conductive segments to create a reconfigurable circuit. |
| FILED | Thursday, August 13, 2015 |
| APPL NO | 14/825855 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/20 (20130101) H01L 41/094 (20130101) Electric Machines Not Otherwise Provided for H02N 2/0095 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/029 (20130101) H05K 3/0008 (20130101) H05K 3/303 (20130101) Original (OR) Class H05K 2201/1009 (20130101) H05K 2203/173 (20130101) H05K 2203/1509 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/613 (20151101) Technical Subjects Covered by Former US Classification Y10T 29/53174 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE47361 | Rumberger, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | William Elmer Rumberger, Jr. (Newtown Square, Pennsylvania); Patrick F. Joyce (Elkton, Maryland); David E. Scheerer (Glen Mills, Pennsylvania) |
| ABSTRACT | A method and apparatus may be present for moving a wing. A plurality of lifting assemblies may be attached to a first plurality of channels in a ring associated with the wing of an aircraft. A plurality of base assemblies may be attached to a plurality of fittings with a second plurality of channels associated with a fuselage of the aircraft. The plurality of lifting assemblies may be moved away from the plurality of base assemblies using a plurality of biasing systems such that the ring may move away from the fuselage. |
| FILED | Friday, November 20, 2015 |
| APPL NO | 14/946776 |
| ART UNIT | 3993 — Central Reexamination Unit (Mechanical) |
| CURRENT CPC | Aeroplanes; Helicopters B64C 3/56 (20130101) Original (OR) Class B64C 29/0033 (20130101) B64C 29/0091 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/40 (20170101) Hoisting, Lifting, Hauling or Pushing, Not Otherwise Provided For, e.g Devices Which Apply a Lifting or Pushing Force Directly to the Surface of a Load B66F 11/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10265425 | Miao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Yubin Miao (Albuquerque, New Mexico); Haixun Guo (Louisville, Kentucky) |
| ABSTRACT | The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states. |
| FILED | Monday, June 20, 2016 |
| APPL NO | 15/186764 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 45/06 (20130101) A61K 51/088 (20130101) Original (OR) Class Peptides C07K 14/685 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/5743 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265433 | Maitland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Duncan J. Maitland (College Station, Texas); Todd Lawrence Landsman (College Station, Texas); Tyler Joseph Touchet (Cypress, Texas); Elizabeth L. Cosgriff-Hernandez (College Station, Texas); Thomas S. Wilson (San Leandro, California) |
| ABSTRACT | An embodiment includes a wound dressing comprising: a shape memory polymer (SMP) foam, including open cells, having first and second states; and a hydrogel (HG) included within the cells; wherein (a) in a first position a composite, including the SMP foam and the HG, is configured to be located proximate a hemorrhagic tissue with the SMP foam in the first state; (b) in a second position the composite is configured to be expanded to the second state against the hemorrhagic tissue when the SMP foam is plasticized at 37° C. depressing a glass transition temperature (Tg) of the SMP foam to below 25° C. Other embodiments are described herein. |
| FILED | Wednesday, March 18, 2015 |
| APPL NO | 14/661215 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/00017 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/18 (20130101) Original (OR) Class A61L 15/26 (20130101) A61L 15/26 (20130101) A61L 15/46 (20130101) A61L 15/425 (20130101) A61L 24/0015 (20130101) A61L 24/0036 (20130101) A61L 24/0094 (20130101) A61L 24/0094 (20130101) A61L 2300/106 (20130101) A61L 2300/404 (20130101) A61L 2400/16 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 75/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265660 | Liu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Wei Liu (Richland, Washington) |
| ABSTRACT | Zeolite membrane sheets for separation of mixtures containing water are provided, as well as methods for making the same. Thin, but robust, zeolite membrane sheets having an inter-grown zeolite crystal film directly on a thin, less than 200 micron thick, porous support sheet free of any surface pores with a size above 10 microns. The zeolite membrane film thickness is less than about 10 microns above the support surface and less than about 5 microns below the support surface. Methods of preparing the membrane are disclosed which include coating of the support sheet surface with a seed coating solution containing the parent zeolite crystals with mean particle sizes from about 0.5 to 2.0 microns at loading of 0.05-0.5 mg/cm2 and subsequent growth of the seeded sheet in a growth reactor loaded with a growth solution over a temperature range of about 45° C. to about 120° C. |
| FILED | Monday, June 08, 2015 |
| APPL NO | 14/733735 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 39/2051 (20130101) B01D 67/0041 (20130101) B01D 67/0046 (20130101) B01D 67/0058 (20130101) B01D 67/0069 (20130101) B01D 69/06 (20130101) B01D 69/10 (20130101) B01D 71/022 (20130101) B01D 71/028 (20130101) Original (OR) Class B01D 2239/10 (20130101) B01D 2239/1216 (20130101) B01D 2323/02 (20130101) B01D 2323/08 (20130101) B01D 2323/18 (20130101) B01D 2325/10 (20130101) B01D 2325/12 (20130101) B01D 2325/20 (20130101) B01D 2325/24 (20130101) B01D 2325/36 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/10 (20130101) B22F 3/18 (20130101) B22F 3/22 (20130101) B22F 5/006 (20130101) B22F 9/30 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) Alloys C22C 19/002 (20130101) C22C 19/03 (20130101) C22C 38/08 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/12014 (20150115) Y10T 428/31678 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265771 | Jagdale et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Delavan Inc (West Des Moines, Iowa) |
| ASSIGNEE(S) | Delavan Inc. (Wes Des Moines, Iowa) |
| INVENTOR(S) | Vijay Jagdale (South Windsor, Connecticut); Tahany I. El-Wardany (Bloomfield, Connecticut); Wayde R. Schmidt (Pomfret Center, Connecticut) |
| ABSTRACT | A method of additive manufacturing includes depositing a layer of absorptive material onto a workpiece, depositing a layer of additive manufacturing stock powder onto the workpiece, and fusing the stock powder to the workpiece using a focused energy source at a wavelength wherein the absorptive material has a higher absorptivity at the wavelength of the focused energy source than the absorptivity of the stock powder at that wavelength. The focused energy source can be a laser, e.g., with a 1064 nm wavelength, for example. |
| FILED | Monday, November 09, 2015 |
| APPL NO | 14/936428 |
| ART UNIT | 1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1003 (20130101) Original (OR) Class B22F 3/1007 (20130101) B22F 3/1007 (20130101) B22F 3/1055 (20130101) B22F 3/1055 (20130101) B22F 7/02 (20130101) B22F 7/06 (20130101) B22F 2201/01 (20130101) B22F 2201/03 (20130101) B22F 2202/11 (20130101) B22F 2301/10 (20130101) B22F 2301/25 (20130101) B22F 2301/052 (20130101) B22F 2302/40 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Alloys C22C 26/00 (20130101) C22C 32/0084 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266405 | Srinivas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
| INVENTOR(S) | Girish Srinivas (Broomfield, Colorado); Steven Charles Gebhard (Golden, Colorado); Robert James Copeland (Westminster, Colorado) |
| ABSTRACT | The present invention provides a steam reforming process for heavy oil or hydrocarbons using a circulating fluidized bed reactor, the process having a reforming step and a regeneration step, wherein the reforming step and the regeneration step comprise a bubbling fluidized reactor containing a fluidizable nickel-containing reforming catalyst and produce hydrogen as a product of the reforming bed. The API gravity of the feedstock may be between −11 and 54, preferably between −11 and 20. The present invention also provides a fluidized bed hydrocarbon steam reforming process using a regenerable catalyst to produce hydrogen, wherein a circulating bed reactor is operated in an alternating manner, switching between two steps: reforming and regeneration; using a mixture of a fluidizable solid and a fluidizable nickel-containing reforming catalyst; producing hydrogen as a product of the reforming step with a minimum hydrogen content of 25 volume percent, preferably at least 60 volume % and more preferably at least 70 volume percent on a dry weight basis. |
| FILED | Tuesday, April 28, 2015 |
| APPL NO | 14/698541 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/10 (20130101) B01J 23/755 (20130101) B01J 35/0006 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/40 (20130101) Original (OR) Class C01B 2203/0233 (20130101) C01B 2203/1058 (20130101) C01B 2203/1082 (20130101) C01B 2203/1235 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266420 | Klausner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC (Gainesville, Florida) |
| INVENTOR(S) | James Klausner (Gainesville, Florida); Kelvin Fnu Randhir (Gainesville, Florida); Nicholas AuYueng (Corvallis, Oregon); Like Li (Gainesville, Florida); Nathan Rhodes (Gainesville, Florida); Amey Anand Barde (Gainesville, Florida); Renwei Mei (Gainesville, Florida); David Worthington Hahn (Gainesville, Florida) |
| ABSTRACT | Disclosed herein is a method comprising heating a strontium-containing compound using radiation in a first reactor; decomposing the strontium-containing compound into an oxide and carbon dioxide as a result of heat generated by the exposure to the radiation; reacting the oxide and the carbon dioxide in a second reactor; where the oxide and carbon dioxide react to produce heat; heating a working fluid using the heat produced in the second reactor; and driving a turbine with the heated working fluid to generate energy. Disclosed herein too is a composition comprising strontium carbonate; and strontium zirconate; where the mass ratio of strontium carbonate to strontium zirconate 2:8 to 8:2. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/317265 |
| ART UNIT | 3748 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 15/04 (20130101) C01B 32/50 (20170801) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 11/06 (20130101) Original (OR) Class C01F 11/187 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 6/003 (20130101) F03G 6/06 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/18 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/46 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/129 (20151101) Y02P 20/134 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266739 | Bronson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Arturo Bronson (El Paso, Texas); Vinod Kumar (El Paso, Texas); Sanjay Shantha-Kumar (El Paso, Texas); Arturo Sepulveda (Santa Teresa, New Mexico) |
| ABSTRACT | Compositions, devices, systems, and methods directed to concentrating solar power are disclosed. In certain aspects, the disclosure is directed to a heat storage material comprising a transformative alloy composition (internal core component) Al—B—Si—Fe/Al2O3—B2O3—SiO2—Fe3O4 embedded in a SiC outer coating. |
| FILED | Monday, January 04, 2016 |
| APPL NO | 14/987683 |
| ART UNIT | 3748 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/12 (20130101) C09K 5/14 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/34 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 6/003 (20130101) Producing or Use of Heat Not Otherwise Provided For F24J 2/07 (20130101) F24J 2/34 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/02 (20130101) F28D 20/003 (20130101) F28D 20/0056 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/41 (20130101) Y02E 10/46 (20130101) Y02E 60/142 (20130101) Y02E 70/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266761 | Zaitseva et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Natalia P. Zaitseva (Livermore, California); M Leslie Carman (San Ramon, California); Nerine Cherepy (Piedmont, California); Andrew M. Glenn (Livermore, California); Sebastien Hamel (Livermore, California); Stephen A. Payne (Castro Valley, California); Benjamin L. Rupert (Berkeley, California) |
| ABSTRACT | In one embodiment, a scintillator material includes a polymer matrix; and a primary dye in the polymer matrix, the primary dye being a fluorescent dye, the primary dye being present in an amount of 5 wt % or more; wherein the scintillator material exhibits an optical response signature for neutrons that is different than an optical response signature for gamma rays. In another embodiment, a scintillator material includes a polymer matrix comprising at least one of: polyvinyl xylene (PVX); polyvinyl diphenyl; and polyvinyl tetrahydronaphthalene; and a primary dye in the polymer matrix, the primary dye being a fluorescent dye, the primary dye being present in an amount greater than 10 wt %. A total loading of dye in the scintillator material is sufficient to cause the scintillator material to exhibit a pulse-shape discrimination (PSD) figure of merit (FOM) of about at least 2.0. |
| FILED | Monday, March 07, 2016 |
| APPL NO | 15/063285 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class C09K 11/025 (20130101) C09K 2211/1007 (20130101) C09K 2211/1475 (20130101) Measurement of Nuclear or X-radiation G01T 1/203 (20130101) G01T 1/2033 (20130101) G01T 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266852 | Beckham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Gregg T. Beckham (Denver, Colorado); Jeffrey G. Linger (Denver, Colorado); Derek R. Vardon (Lakewood, Colorado); Michael T. Guarnieri (Denver, Colorado); Eric M. Karp (Lakewood, Colorado); Mary Ann Franden (Centennial, Colorado); Christopher W. Johnson (Denver, Colorado); Timothy J. Strathmann (Champaign, Illinois); Philip T. Pienkos (Lakewood, Colorado) |
| ABSTRACT | Disclosed herein are methods for the production of fuels, chemicals, or materials from biomass-derived lignin, cellulose, and hemicellulose. Also provided are methods for the production of polyhydroxyalkanoates from lignocellulosic biomass and the subsequent thermal and catalytic conversion of polyhydroxyalkanoates to hydrocarbons. In addition, methods for the production of ethanol from the fermentation of polysaccharides are described. |
| FILED | Monday, December 08, 2014 |
| APPL NO | 14/563299 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/002 (20130101) C12P 5/02 (20130101) Original (OR) Class C12P 7/42 (20130101) C12P 7/625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266915 | Paranthaman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); Alger Alternative Energy, LLC (Brawley, California) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); Alger Alternative Energy, LLC (Brawley, California) |
| INVENTOR(S) | Mariappan Parans Paranthaman (Knoxville, Tennessee); Ramesh R. Bhave (Knoxville, Tennessee); Bruce A. Moyer (Oak Ridge, Tennessee); Stephen Harrison (Benicia, California) |
| ABSTRACT | A solid particulate composition useful in extracting a lithium salt from aqueous solutions, the composition comprising lithium, metal atoms, oxygen atoms, and at least one anionic species (X) selected from halide, nitrate, sulfate, carbonate and bicarbonate, all in a framework structure, wherein said metal atoms are selected from at least one of oxophilic main group metal and oxophilic transition metal atoms, provided that, if the metal atoms comprise aluminum atoms, then at least 10 mol % of said aluminum atoms are substituted with at least one metal atom selected from said at least one oxophilic main group and oxophilic transition metal atoms, other than aluminum, and wherein said lithium is present in said composition in an amount less than a saturated amount in order to permit extraction of lithium salt. Methods for extracting and recovering a lithium salt from an aqueous solution by use of the above-described composition are also described. |
| FILED | Thursday, April 14, 2016 |
| APPL NO | 15/099045 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/08 (20130101) B01J 20/18 (20130101) B01J 39/02 (20130101) B01J 39/10 (20130101) B01J 39/14 (20130101) Non-metallic Elements; Compounds Thereof; C01B 39/50 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/42 (20130101) C22B 7/006 (20130101) C22B 26/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266949 | Biener et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Juergen Biener (San Leandro, California); Monika M. Biener (San Leandro, California); Alex V. Hamza (Livermore, California); Marcus Baeumer (Bremen, Germany); Arne Wittstock (Bremen, Germany); Joerg Weissmueller (Stutensee, Germany); Dominik Kramer (Eggenstein-Leopoldshafen, Germany); Raghavan Nadar Viswanath (Eggenstein-Leopoldshafen, Germany) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Juergen Biener (San Leandro, California); Monika M. Biener (San Leandro, California); Alex V. Hamza (Livermore, California); Marcus Baeumer (Bremen, Germany); Arne Wittstock (Bremen, Germany); Joerg Weissmueller (Stutensee, Germany); Dominik Kramer (Eggenstein-Leopoldshafen, Germany); Raghavan Nadar Viswanath (Eggenstein-Leopoldshafen, Germany) |
| ABSTRACT | A method of controlling macroscopic strain of a porous structure includes contacting a porous structure with a modifying agent which chemically adsorbs to a surface of the porous structure and modifies an existing surface stress of the porous structure. A device in one embodiment includes a porous metal structure, which when contacted with a modifying agent which chemically adsorbs to a surface of the porous metal structure, exhibits a volumetric change due to modification of an existing surface stress of the porous metal structure; and a mechanism for detecting the volumetric change. Additional methods and systems are also presented. |
| FILED | Friday, October 10, 2008 |
| APPL NO | 12/249630 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/00 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/25 (20130101) F05D 2300/133 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267258 | Maki et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ford Global Technologies, LLC (Dearborn, Michigan) |
| ASSIGNEE(S) | Ford Global Technologies, LLC (Dearborn, Michigan) |
| INVENTOR(S) | Clifford E. Maki (New Hudson, Michigan); Timothy George Beyer (Troy, Michigan); Arup Kumar Gangopadhyay (Novi, Michigan); Hamed Ghaednia (West Bloomfield, Michigan); Larry Dean Elie (Ypsilanti, Michigan); James Maurice Boileau (Novi, Michigan) |
| ABSTRACT | Methods of honing a surface are disclosed. The method may include spraying a coating having an initial average bulk porosity onto an engine bore wall and honing the coating to create an intermediate honed surface. The method may then include cleaning the intermediate honed surface and honing the intermediate honed surface with a cutting force of, for example, 110-130 kgf after the cleaning step. This may create a honed surface having an average porosity greater than the initial average bulk porosity. The methods may create a honed surface having a porosity that is more porous than the initially sprayed coating. The increased porosity of the honed surface may allow for increased oil retention in, for example, engine bores. |
| FILED | Monday, December 05, 2016 |
| APPL NO | 15/369013 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Machines, Devices, or Processes for Grinding or Polishing; Dressing or Conditioning of Abrading Surfaces; Feeding of Grinding, Polishing, or Lapping Agents B24B 33/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/18 (20130101) C23C 4/134 (20160101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 1/004 (20130101) Original (OR) Class F02F 2200/00 (20130101) F02F 2200/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267456 | Reddi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Krishna Reddi (Westmont, Illinois); Amgad Elgowainy (Lisle, Illinois) |
| ABSTRACT | A method and system are provided for operating refueling station tube-trailers and compressors to reduce hydrogen refueling cost. A hydrogen refueling station includes a two-tier fuel supply of pressure vessels on a refueling station tube-trailer, with a first tier and a second tier of pressure vessels including at least one or more pressure vessels connected together. A separate control unit is coupled to the first tier and the second tier of pressure vessels with each of the control units coupled to a compressor. The compressor is coupled to a high pressure buffer storage by a separate control unit. In operation, pressure is monitored in the each tier. Hydrogen is consolidated selectively between the first tier of pressure vessel banks, the second tier pressure vessels, and the high pressure buffer. Based upon monitored pressures, one of the first tier of pressure vessels, the second tier pressure vessel banks, and the high pressure buffer is used to refuel vehicles. |
| FILED | Thursday, September 22, 2016 |
| APPL NO | 15/272622 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 5/06 (20130101) Original (OR) Class F17C 13/025 (20130101) F17C 2221/012 (20130101) F17C 2223/035 (20130101) F17C 2250/032 (20130101) F17C 2250/043 (20130101) F17C 2270/0763 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267600 | Hower |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Brent Hower (Kansas City, Missouri) |
| ABSTRACT | An explosive device detection and expulsion system broadly comprising a detection subsystem for sensing an IED attached to a vehicle and an expulsion subsystem for expelling the IED from the vehicle. The detection subsystem includes a sensor for detecting an IED via an electromagnetic field change or capacitance change, vibrations, and/or heat, and a controller for activating the expulsion subsystem upon receiving a detection signal from the sensor. The expulsion subsystem includes a deployable panel configured to be attached to the vehicle and a deployable mechanism for shifting the deployable panel from an undeployed state to a deployed state so as to expel the IED from the vehicle. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 15/692632 |
| ART UNIT | 3612 — Printing/Measuring and Testing |
| CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/007 (20130101) Original (OR) Class F41H 7/00 (20130101) F41H 11/32 (20130101) F41H 11/136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267680 | Shields |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Eric A. Shields (Albuquerque, New Mexico) |
| ABSTRACT | Technologies pertaining to a compressive sensing snapshot spectrometer are described herein. Light is focused through an array of filters onto an array of optical detectors by way of an optical objective. Each detector in the array receives light from a single respective filter in the filters. Each filter in the filters has a spectral transmittance function that overlaps a spectral transmittance function of at least one other filter. A compressive sensing algorithm is executed over outputs of the detectors based upon the known spectral transmittance functions of the filters. Based upon the execution of the compressive sensing algorithm, intensity values of the light are identified for a number of spectral bins that is greater than a number of detectors in the array. |
| FILED | Tuesday, May 09, 2017 |
| APPL NO | 15/590783 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/26 (20130101) G01J 3/2823 (20130101) Original (OR) Class G01J 2003/283 (20130101) G01J 2003/1213 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267788 | Schoeniger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Joseph S. Schoeniger (Oakland, California); Peter Anderson (Bothell, Washington) |
| ABSTRACT | A method including identifying one or more structures in adjacent sequences of one or more proteins that can be mimicked by a peptide; and assembling a peptide that mimics the one or more secondary structures. A method including assembling epitopes of linked pairs of discontiguous peptide subsequences that mimic one or more structures in sequences of a protein; and assaying antibodies against the epitopes. |
| FILED | Monday, January 20, 2014 |
| APPL NO | 14/159308 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/531 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267895 | Naething et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Richard M. Naething (Albuquerque, New Mexico); Richard C. Ormesher (Albuquerque, New Mexico) |
| ABSTRACT | Various technologies for identifying RF emitters in geolocation datasets are described herein. Doppler signatures of RF emitters and geolocation data of objects in a scene are collected simultaneously, then range-rate profiles of the movement of the RF emitters and the objects in the scene are computed. An RF emitter is identified in a geolocation dataset by comparing the motion of the RF emitter with the motion of an object in the scene as described by the respective range-rate profiles. |
| FILED | Thursday, October 29, 2015 |
| APPL NO | 14/927138 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/46 (20130101) G01S 3/52 (20130101) G01S 5/04 (20130101) Original (OR) Class G01S 5/0268 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267896 | Rodenbeck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Jose Silva-Martinez (College Station, Texas); John Mincey (Bryan, Texas); Eric Su (Santa Clara, California) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Jose Silva-Martinez (College Station, Texas); John Mincey (Bryan, Texas); Eric Su (Santa Clara, California) |
| INVENTOR(S) | Christopher T. Rodenbeck (Alexandria, Virginia); Jose Silva-Martinez (College Station, Texas); John Mincey (Bryan, Texas); Eric Su (Santa Clara, California) |
| ABSTRACT | A variable bandwidth filter is described herein, wherein a bandwidth of a passband of the variable bandwidth filter is dynamically tunable. The variable bandwidth tuner is implemented on a CMOS chip, and acts to filter analog signals. The variable bandwidth filter comprises a plurality of finite impulse response (FIR) filters, wherein each FIR filter comprises a plurality of tunable transconductors. The tunable transconductors are tunable in their gain. |
| FILED | Tuesday, August 18, 2015 |
| APPL NO | 14/828677 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/282 (20130101) G01S 7/285 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267957 | Kamali et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Seyedeh Mahsa Kamali (Pasadena, California); Ehsan Arbabi (Pasadena, California); Amir Arbabi (Pasadena, California); Andrei Faraon (La Canada Flintridge, California) |
| ABSTRACT | Structures for scattering light at multiple wavelengths are disclosed. Scattering elements are fabricated with different geometric dimensions and arrangements, to scatter or focus light at the same focal distance for each wavelength, or at different focal distances according to the desired application. The scattering elements fabricated on a substrate can be peeled off with a polymer matrix and attached to a lens to modify the optical properties of the lens. |
| FILED | Wednesday, May 09, 2018 |
| APPL NO | 15/975521 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/0226 (20130101) Original (OR) Class G02B 5/0242 (20130101) G02B 5/0263 (20130101) G02B 5/0268 (20130101) G02B 5/0278 (20130101) G02B 5/1876 (20130101) G02B 27/0025 (20130101) G02B 27/4211 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268165 | Schwartz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Jacob Schwartz (Princeton, New Jersey); Michael Jaworski (Lawrenceville, New Jersey) |
| ABSTRACT | A liquid metal leak detector system including a direct current (DC) power supply and a plurality of analog to digital converters connected to the DC power supply. Each converter includes a liquid metal switch, where the liquid metal switch is closed in event of a liquid metal leak since the liquid metal leak causes electrical continuity between a conductive sheeting and a housing for liquid metal. The converter also includes a comparator connected to both the liquid metal switch for converting an analog signal into a digital signal, wherein the digital signal is configured such that a high signal constitutes no leak and a low signal constitutes a leak. An AND gate is also connected to each of the plurality of converters for combining all of the digital signals output from the converters, the AND gate configured such that the AND gate outputs a high signal if all of its inputs are high and a low signal if any input is low. |
| FILED | Thursday, November 05, 2015 |
| APPL NO | 14/933678 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/18 (20130101) G01M 3/40 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/392 (20190101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 9/00 (20130101) G05B 9/02 (20130101) Original (OR) Class G05B 9/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268384 | Aho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Michael E. Aho (Rochester, Minnesota); Thomas M. Gooding (Rochester, Minnesota); Bryan S. Rosenburg (Cortlandt Manor, New York) |
| ABSTRACT | Techniques for transferring files between machines include creating a zero-length target file on non-volatile storage, truncating the file to a desired size, and allocating storage on the non-volatile storage for each block of the target file. The technique also includes determining a logical block address (LBA) for each location in the target file. The technique further includes sending a request to an input/output (I/O) node to transfer a source file to the non-volatile storage, where the request includes a mapping between the LBAs and file offsets. The technique includes opening the source file and a block device at the I/O node. The technique further includes reading each block from the source file and writing each block to the target file on the non-volatile storage utilizing the block device, and then closing the source file and the block device. |
| FILED | Friday, September 16, 2016 |
| APPL NO | 15/267415 |
| ART UNIT | 2135 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/061 (20130101) Original (OR) Class G06F 3/067 (20130101) G06F 3/0643 (20130101) G06F 17/30091 (20130101) G06F 17/30917 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268585 | Ranjan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Ashish Ranjan (West Lafayette, Indiana); Vivek Kozhikkottu (Hillsboro, Oregon) |
| ABSTRACT | An apparatus having a memory controller is described. The memory controller includes prefetch circuitry to prefetch, from a memory, data having a same row address in response to the memory controller's servicing of its request stream being stalled because of a timing constraint that prevents a change in row address. The memory controller also includes a cache to cache the prefetched data. The memory controller also includes circuitry to compare addresses of read requests in the memory controller's request stream against respective addresses of the prefetched data in the cache and to service those of the requests in the memory controller's request stream having a matching address with corresponding ones of the prefetched data in the cache. |
| FILED | Tuesday, June 28, 2016 |
| APPL NO | 15/195887 |
| ART UNIT | 2133 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0842 (20130101) G06F 12/0862 (20130101) Original (OR) Class G06F 12/0866 (20130101) G06F 2212/312 (20130101) G06F 2212/602 (20130101) G06F 2212/1016 (20130101) G06F 2212/6022 (20130101) Static Stores G11C 2207/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268900 | Divakaran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Ajay Divakaran (Monmouth Junction, New Jersey); Qian Yu (Plainsboro, New Jersey); Amir Tamrakar (Philadelphia, Pennsylvania); Harpreet Singh Sawhney (Princeton Junction, New Jersey); Jiejie Zhu (East Windsor, New Jersey); Omar Javed (Franklin Park, New Jersey); Jingen Liu (Plainsboro, New Jersey); Hui Cheng (Bridgewater, New Jersey); Jayakrishnan Eledath (Robbinsville, New Jersey) |
| ABSTRACT | A system for object detection and tracking includes technologies to, among other things, detect and track moving objects, such as pedestrians and/or vehicles, in a real-world environment, handle static and dynamic occlusions, and continue tracking moving objects across the fields of view of multiple different cameras. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 15/905937 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00771 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10269460 | Butchart |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NuScale Power, LLC (Corvallis, Oregon) |
| ASSIGNEE(S) | NUSCALE POWER, LLC (Corvallis, Oregon) |
| INVENTOR(S) | Paul Butchart (Corvallis, Oregon) |
| ABSTRACT | A rod position indication system includes a drive rod operably coupled to a control rod that is configured to be both withdrawn from and inserted into a reactor core. A number of sensing devices are arranged along a path of the drive rod, and an end of the drive rod passes by or through one or more of the sensing devices in response to movement of the control rod relative to the reactor core. The sensing devices are arranged into a plurality of groups, and each group includes two or more of the sensing devices electrically coupled together. The rod position indication system further includes a control rod monitoring device electrically coupled to each group of sensing devices by a routing wire. |
| FILED | Friday, July 31, 2015 |
| APPL NO | 14/814904 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 7/36 (20130101) G21C 17/12 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/39 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10269525 | Marcus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CLEMSON UNIVERSITY (Clemson, South Carolina); Lawrence Berkeley National Laboratory (Berkeley, California); Pacific Northwest National Laboratory (Richland, Washington) |
| ASSIGNEE(S) | Clemson University Research Foundation (Clemson, South Carolina); Battelle Memorial Institute on behalf of Pacific Northwest National Laboratory (Richland, Washington); The Regents of the University of California Lawrence Berkeley National Laboratory (Berkeley, California) |
| INVENTOR(S) | R. Kenneth Marcus (Clemson, South Carolina); Charles Derrick Quarles, Jr. (San Jose, California); Richard E. Russo (Berkeley, California); David W. Koppenaal (Richland, Washington); Charles J. Barinaga (Richland, Washington); Anthony J. Carado (Richland, Washington) |
| ABSTRACT | A liquid sampling, atmospheric pressure, glow discharge (LS-APGD) device as well as systems that incorporate the device and methods for using the device and systems are described. The LS-APGD includes a hollow capillary for delivering an electrolyte solution to a glow discharge space. The device also includes a counter electrode in the form of a second hollow capillary that can deliver the analyte into the glow discharge space. A voltage across the electrolyte solution and the counter electrode creates the microplasma within the glow discharge space that interacts with the analyte to move it to a higher energy state (vaporization, excitation, and/or ionization of the analyte). |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/359969 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/443 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 27/16 (20130101) H01J 27/022 (20130101) Original (OR) Class H01J 49/105 (20130101) H01J 49/145 (20130101) H01J 49/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10269592 | Doany et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Fuad Elias Doany (Katonah, New York); Mark Schultz (Ossining, New York) |
| ABSTRACT | Matching of coefficient of thermal expansion for heat spreaders and carrier die can facilitate optoelectronic die alignment. In one example, an apparatus comprises a carrier die comprising a first coefficient of thermal expansion, two or more optoelectronic die disposed on the carrier die, and a spreader. The spreader can comprise a second material coefficient of thermal expansion matched to the first coefficient of thermal expansion. Additionally, a thermal interface material is disposed between the spreader and the one or more optoelectronic die. |
| FILED | Thursday, November 30, 2017 |
| APPL NO | 15/827562 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/486 (20130101) H01L 21/4882 (20130101) H01L 21/67103 (20130101) Original (OR) Class H01L 23/36 (20130101) H01L 23/3107 (20130101) H01L 24/49 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/722 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10269994 | Haight et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Richard A. Haight (Mahopac, New York); James B. Hannon (Lake Lincolndale, New York); Satoshi Oida (Yorktown Heights, New York) |
| ABSTRACT | A method for forming a back contact on an absorber layer in a photovoltaic device includes forming a two dimensional material on a first substrate. An absorber layer including Cu—Zn—Sn—S(Se)(CZTSSe) is grown over the first substrate on the two dimensional material. A buffer layer is grown on the absorber layer on a side opposite the two dimensional material. The absorber layer is exfoliated from the two dimensional material to remove the first substrate from a backside of the absorber layer opposite the buffer layer. A back contact is deposited on the absorber layer. |
| FILED | Monday, December 18, 2017 |
| APPL NO | 15/845455 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/072 (20130101) H01L 31/0324 (20130101) H01L 31/0326 (20130101) H01L 31/0445 (20141201) H01L 31/1892 (20130101) H01L 31/1896 (20130101) H01L 31/02168 (20130101) H01L 31/03923 (20130101) H01L 31/03925 (20130101) H01L 31/03926 (20130101) H01L 31/022425 (20130101) H01L 31/022441 (20130101) Original (OR) Class H01L 31/022466 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270251 | Neely et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jason C. Neely (Albuquerque, New Mexico); Steven F. Glover (Albuquerque, New Mexico) |
| ABSTRACT | An emulator apparatus that emulates entities included in a microgrid is described herein. The emulator apparatus emulates a load with time-varying inductance/resistance or an energy storage device or combination of energy storage devices. The emulator apparatus is electrically coupled to a system or device that is desirably tested/maintained/designed. The emulator apparatus emulates a particular device, and response of the system of device to the emulated device is monitored for purposes of design, testing, or maintenance. |
| FILED | Wednesday, October 24, 2012 |
| APPL NO | 13/659822 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/38 (20130101) Original (OR) Class H02J 2003/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270311 | Morrison |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Darrell Morrison (Eagle Lake, Minnesota) |
| ASSIGNEE(S) | KATO ENGINEERING INC. (North Mankato, Minnesota) |
| INVENTOR(S) | Darrell Morrison (Eagle Lake, Minnesota) |
| ABSTRACT | A superconducting electrical machine includes a rotor and a stator. The stator defines a cavity. The rotor is configured to rotate about a longitudinal axis. The rotor is disposed at least partially within the cavity. The rotor includes a shaft configured to rotate with the rotor, a rotor active section including at least a rotor torque tube and a superconductor, and a first re-entrant end attaching the shaft to the rotor active section. At most a threshold fraction of a bending force applied to the shaft is communicated to the rotor active section. |
| FILED | Wednesday, March 18, 2015 |
| APPL NO | 14/662084 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Wind Motors F03D 9/25 (20160501) F03D 15/20 (20160501) F03D 80/60 (20160501) F03D 80/70 (20160501) Dynamo-electric Machines H02K 7/003 (20130101) Original (OR) Class H02K 7/1838 (20130101) H02K 55/04 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/725 (20130101) Y02E 40/625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270368 | Sampayan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Stephen E. Sampayan (Manteca, California) |
| ABSTRACT | A multi-stage electric voltage converter is disclosed. The converter comprises a voltage source and multiple stages. Each stage of the multiple stages comprises a first and a second and a third switch, and a capacitor, wherein the capacitor is coupled to the voltage source by the first and the second switches and each stage is coupled to a different stage or to an output of the multi-stage electric voltage converter by the third switch so as to allow the capacitor to be charged by the voltage source when the first and the second switches are closed and the third switch is open, and to allow the capacitor to be connected to the output of the multi-stage electric voltage converter when the first and the second switches are open and the third switch is closed. |
| FILED | Friday, December 02, 2016 |
| APPL NO | 15/368384 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/32 (20130101) H02J 3/36 (20130101) H02J 3/382 (20130101) H02J 3/383 (20130101) H02J 3/386 (20130101) H02J 7/34 (20130101) H02J 9/062 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/12 (20130101) H02M 3/07 (20130101) H02M 7/70 (20130101) Original (OR) Class H02M 7/797 (20130101) H02M 2003/072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270444 | Luckett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Edward James Luckett (Fort Collins, Colorado); Christopher Allan Poirier (Fort Collins, Colorado) |
| ABSTRACT | According to examples, an apparatus may include a field effect transistor (FET), a driver to receive an input signal and to output a driver output signal, and a gate to receive the input signal. The apparatus may also include a delay element to receive the driver output signal and to output a delayed signal to the gate after a delay from receipt of the driver output signal, in which the gate is to output a gate output signal to the FET in response to receipt of the input signal and the delayed signal, and in which receipt of the gate output signal by the FET drives the FET to provide a boost to the driver output signal. |
| FILED | Wednesday, April 04, 2018 |
| APPL NO | 15/945471 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 19/00323 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270787 | Teuton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jeremy R. Teuton (Pasco, Washington); Jeromy M. Markwort (Kennewick, Washington) |
| ABSTRACT | A method and system for administering an interactive computer network and more particularly to performing security in a network of interactive electronic components, such as a computer network using a currency-based transactional economy model where scarcity serves as a limiting factor to accessing and engaging in various activities within the system. |
| FILED | Monday, May 23, 2016 |
| APPL NO | 15/161938 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 40/02 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/1416 (20130101) Original (OR) Class H04L 63/1441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10265155 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Helen H. Lu (New York, New York); Jeffrey Spalazzi (Staten Island, New York); Kristen L. Moffat (Oakmont, Pennsylvania); William N. Levine (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Helen H. Lu (New York, New York); Jeffrey Spalazzi (Staten Island, New York); Kristen L. Moffat (Oakmont, Pennsylvania); William N. Levine (New York, New York) |
| ABSTRACT | An implantable device is provided for soft-tissue or soft tissue-to-bone repair, fixation, augmentation, or replacement that includes a biomimetic and biodegradable nanofiber scaffold. Also provided is a fully synthetic implantable multiphased scaffold which includes, in a single continuous construct, a plurality of phases to mimic the natural anatomy of a tendon or ligament and their insertion sites. Also provided are scaffold apparatuses for musculoskeletal tissue engineering. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 14/503053 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/08 (20130101) Original (OR) Class A61F 2/0811 (20130101) A61F 2002/0858 (20130101) A61F 2210/0004 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/32 (20130101) A61K 35/32 (20130101) A61K 38/18 (20130101) A61K 38/18 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 2430/34 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265405 | Peppas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Nicholas A. Peppas (Austin, Texas); Sarena D. Horava (Austin, Texas) |
| ABSTRACT | In some aspects, a composition comprising a pH-sensitive crosslinked copolymer of methacrylic acid and poly(ethylene glycol) monomethyl ether methacrylate and a therapeutic protein is provided. In some embodiments, the therapeutic protein is a high molecular weight protein such as factor VIII or factor IX. In some embodiments, the composition is orally administered to a patient to treat a disease or disorder such as, e.g., hemophilia. |
| FILED | Tuesday, November 17, 2015 |
| APPL NO | 14/944173 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 38/4846 (20130101) A61K 47/58 (20170801) A61K 47/60 (20170801) A61K 47/6903 (20170801) A61K 47/48176 (20130101) Original (OR) Class Enzymes C12Y 304/21022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265407 | Mellman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Ira S. Mellman (San Francisco, California); Tarek M. Fahmy (New Haven, Connecticut); William Mark Saltzman (New Haven, Connecticut); Michael J. Caplan (Woodbridge, Connecticut) |
| ABSTRACT | Modular nanoparticle vaccine compositions and methods of making and using the same have been developed. Modular nanoparticle vaccine compositions comprise an antigen encapsulated in a polymeric particle and adaptor elements which modularly couple functional elements to the particle. The modular design of these vaccine compositions, which involves flexible addition and subtraction of antigen, adjuvant, immune potentiators, molecular recognition and transport mediation elements, as well as intracellular uptake mediators, allows for exquisite control over variables that are important in optimizing an effective vaccine delivery system. |
| FILED | Monday, November 10, 2014 |
| APPL NO | 14/537541 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/51 (20130101) A61K 9/141 (20130101) A61K 9/5084 (20130101) A61K 9/5153 (20130101) A61K 9/5161 (20130101) A61K 39/001 (20130101) A61K 39/02 (20130101) A61K 39/0005 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 39/35 (20130101) A61K 39/39 (20130101) A61K 39/145 (20130101) A61K 39/385 (20130101) A61K 39/3955 (20130101) A61K 47/58 (20170801) A61K 47/62 (20170801) A61K 47/6849 (20170801) A61K 47/6937 (20170801) A61K 47/48915 (20130101) Original (OR) Class A61K 2039/57 (20130101) A61K 2039/70 (20130101) A61K 2039/6093 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/47 (20130101) C07K 14/705 (20130101) C07K 16/18 (20130101) C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/2851 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16134 (20130101) C12N 2710/16234 (20130101) C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265408 | Chmielewski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jean Anne Chmielewski (West Lafayette, Indiana); Mohamed Seleem (West Lafayette, Indiana) |
| ABSTRACT | The present disclosure relates to novel cleavable conjugates of antibiotics and an antibacterial cell-penetrating peptide, and methods to make and use the novel cleavable conjugates of antibiotics and an antibacterial cell-penetrating peptide. |
| FILED | Tuesday, July 31, 2018 |
| APPL NO | 16/050472 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/395 (20130101) A61K 31/7036 (20130101) A61K 31/7048 (20130101) A61K 47/61 (20170801) A61K 47/65 (20170801) A61K 47/552 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265440 | James et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| ASSIGNEE(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| INVENTOR(S) | Susan P. James (Bellvue, Colorado); Susan S. Yonemura (Fort Collins, Colorado); Ariane Vartanian (Santa Clara, California) |
| ABSTRACT | The present invention relates to polymeric materials including a glycosaminoglycan networked with a polyolefin-containing polymer. The present invention also relates to hydrogels containing the polymeric materials. The present invention further relates to methods of synthesizing the polymeric materials and hydrogels of the present invention. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/467756 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0024 (20130101) A61K 31/726 (20130101) A61K 31/727 (20130101) A61K 31/728 (20130101) A61K 31/737 (20130101) A61K 47/32 (20130101) A61K 47/36 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/60 (20130101) A61L 15/60 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/20 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 2400/06 (20130101) A61L 2430/06 (20130101) A61L 2430/38 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 251/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/02 (20130101) C08G 2210/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2351/02 (20130101) Compositions of Macromolecular Compounds C08L 51/02 (20130101) C08L 51/003 (20130101) C08L 51/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265646 | Green et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Alexander A. Green (Boston, Massachusetts); Mark C. Hersam (Wilmette, Illinois) |
| ABSTRACT | The present teachings provide methods for sorting nanotubes according to their wall number, and optionally further in terms of their diameter, electronic type, and/or chirality. Also provided are highly enriched nanotube populations provided thereby and articles of manufacture including such populations. |
| FILED | Wednesday, February 18, 2015 |
| APPL NO | 14/625333 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Separation B01D 21/262 (20130101) Original (OR) Class Flotation; Differential Sedimentation B03D 3/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/172 (20170801) C01B 2202/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265683 | Hart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Anastasios John Hart (Somerville, Massachusetts); Brian L. Wardle (Lexington, Massachusetts); Enrique J. Garcia (Saragossa, Spain); Alexander H. Slocum (Bow, New Hampshire) |
| ABSTRACT | The present invention provides methods for uniform growth of nanostructures such as nanotubes (e.g., carbon nanotubes) on the surface of a substrate, wherein the long axes of the nanostructures may be substantially aligned. The nanostructures may be further processed for use in various applications, such as composite materials. For example, a set of aligned nanostructures may be formed and transferred, either in bulk or to another surface, to another material to enhance the properties of the material. In some cases, the nanostructures may enhance the mechanical properties of a material, for example, providing mechanical reinforcement at an interface between two materials or plies. In some cases, the nanostructures may enhance thermal and/or electronic properties of a material. The present invention also provides systems and methods for growth of nanostructures, including batch processes and continuous processes. |
| FILED | Tuesday, June 14, 2016 |
| APPL NO | 15/182403 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 23/745 (20130101) Original (OR) Class Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 1/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/16 (20170801) C01B 32/18 (20170801) C01B 32/158 (20170801) C01B 32/162 (20170801) C01B 32/164 (20170801) C01B 2202/08 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/127 (20130101) D01F 9/133 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/74 (20130101) D06M 23/08 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/582 (20151101) Y02P 20/584 (20151101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/742 (20130101) Y10S 977/843 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265862 | Alqasemi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Redwan Alqasemi (Wesley Chapel, Florida); Paul Mitzlaff (Palm Harbor, Florida); Andoni Aguirrezabal (Tampa, Florida); Lei Wu (Tampa, Florida); Karl Rothe (Rockledge, Florida); Rajiv Dubey (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Redwan Alqasemi (Wesley Chapel, Florida); Paul Mitzlaff (Palm Harbor, Florida); Andoni Aguirrezabal (Tampa, Florida); Lei Wu (Tampa, Florida); Karl Rothe (Rockledge, Florida); Rajiv Dubey (Tampa, Florida) |
| ABSTRACT | In one embodiment, a robotic end effector configured to mount to a robotic manipulator includes gripping elements configured to grasp objects, a drive mechanism configured to open and close the gripping elements, and a central controller configured to control operation of the drive mechanism and the gripper elements, the central controller hosting a control program that enables control of the end effector independent of the robotic manipulator. |
| FILED | Monday, June 19, 2017 |
| APPL NO | 15/626279 |
| ART UNIT | 3652 — Material and Article Handling |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 15/022 (20130101) B25J 15/0038 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266397 | Koley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Goutam Koley (Anderson, South Carolina); Abdul Talukdar (Hillsboro, Oregon) |
| ABSTRACT | A microcantilever based photoacoustic sensor is generally provided. In one embodiment, the microcantilever includes: a substrate; a GaN layer on the substrate, wherein the GaN layer defines a cantilever extending beyond an edge of the substrate, with a base area of the cantilever defined by the area spanning the edge of the substrate; a heterojunction field effect transistor (HFET) deflection transducer positioned on the cantilever; a pair of electrical contacts, each electrically connected to the HFET deflection transducer; and a microfluidic channel in fluid communication with an analyte reservoir, wherein the analyte reservoir is positioned at the base of the cantilever. A sensing system is also generally provided. |
| FILED | Wednesday, August 12, 2015 |
| APPL NO | 14/824269 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502707 (20130101) B01L 2300/0663 (20130101) B01L 2300/0877 (20130101) B01L 2400/0484 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2203/0118 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/0015 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) G01N 29/022 (20130101) G01N 29/222 (20130101) G01N 29/2425 (20130101) G01N 2291/014 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/02381 (20130101) H01L 21/02439 (20130101) H01L 29/778 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) H01L 29/66431 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266413 | Adamson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Douglas H. Adamson (Mansfield Center, Connecticut); Harish Kumar (Bethel, Connecticut) |
| ABSTRACT | A method to fractionate and isolate components of oxidized graphene material is provided that includes fractionating a system that includes graphene oxide, a solvent and water, wherein the fractionation creates two phases or fractions: (i) a water phase or fraction that contains highly oxidized graphene oxide, and (ii) a solvent-in-water emulsion phase or fraction that contains a graphene-based material. The graphene-based material is recovered from the solvent-in-water phase or fraction. Fractionation of the solvent-in-water emulsion phase or fraction may be repeated. The graphene-based material (uGO) may be used in a range of applications, e.g., a medical device, a nanoelectronic, an electromechanical system, a sensor, a composite, a catalysis, and energy storage device, and an optics application. |
| FILED | Friday, November 03, 2017 |
| APPL NO | 15/802733 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 67/0093 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/23 (20170801) C01B 32/192 (20170801) Original (OR) Class C01B 32/198 (20170801) C01B 2204/02 (20130101) C01B 2204/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266623 | Carrow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Brad P. Carrow (Princeton, New Jersey); Wei Zhang (Exton, Pennsylvania) |
| ABSTRACT | In one aspect, a chelating phosphine-phosphonic diamide (PPDA) ligand is described herein for constructing transition metal complexes operable for catalysis of olefin polymerization, including copolymerization of ethylene with polar monomer. |
| FILED | Friday, June 26, 2015 |
| APPL NO | 15/322347 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 4/80 (20130101) C08F 4/7014 (20130101) C08F 4/7014 (20130101) C08F 10/02 (20130101) C08F 110/02 (20130101) C08F 210/02 (20130101) Original (OR) Class C08F 210/02 (20130101) C08F 210/02 (20130101) C08F 210/02 (20130101) C08F 210/02 (20130101) C08F 210/02 (20130101) C08F 216/12 (20130101) C08F 216/18 (20130101) C08F 218/12 (20130101) C08F 220/00 (20130101) C08F 220/02 (20130101) C08F 220/06 (20130101) C08F 220/06 (20130101) C08F 220/10 (20130101) C08F 220/14 (20130101) C08F 220/14 (20130101) C08F 220/44 (20130101) C08F 2410/01 (20130101) C08F 2500/02 (20130101) C08F 2500/02 (20130101) C08F 2500/02 (20130101) C08F 2500/02 (20130101) C08F 2500/02 (20130101) C08F 2500/03 (20130101) C08F 2500/03 (20130101) C08F 2500/03 (20130101) C08F 2500/03 (20130101) C08F 2500/03 (20130101) C08F 2500/10 (20130101) C08F 2500/10 (20130101) C08F 2500/10 (20130101) C08F 2500/10 (20130101) C08F 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266765 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Wei Chen (Arlington, Texas); Lun Ma (Arlington, Texas) |
| ABSTRACT | This invention relates to new phosphor materials exhibiting luminescence and methods for their production. More particularly, the invention relates to new europium-doped zinc sulfide-manganese (ZnS:Mn,Eu) phosphors and use thereof for radiation detection. |
| FILED | Thursday, November 06, 2014 |
| APPL NO | 15/034124 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/773 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266806 | Khetani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Salman R. Khetani (Fort Collins, Colorado); Dustin R. Berger (Fort Collins, Colorado); Brenton R. Ware (Fort Collins, Colorado) |
| ABSTRACT | The present disclosure provides co-cultures of human pluripotent stem cell derived hepatocytes and at least one non-parenchymal cell population in vitro, methods of preparing the co-cultures and methods of using the co-cultures for high throughput screening and evaluation of drug candidates. The stem cell derived hepatocyte co-culture system provides an in vitro model in which cell viability and relatively mature hepatocyte phenotype of stem cell derived hepatocytes are maintained for extended periods relative to conventional monoculture. |
| FILED | Wednesday, January 14, 2015 |
| APPL NO | 14/596787 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) Original (OR) Class C12N 2501/39 (20130101) C12N 2501/237 (20130101) C12N 2502/13 (20130101) C12N 2503/02 (20130101) C12N 2533/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266888 | Daugharthy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Evan R. Daugharthy (Cambridge, Massachusetts); Richard C. Terry (Carlisle, Massachusetts); Je-Hyuk Lee (Allston, Massachusetts); George M. Church (Brookline, Massachusetts); Benjamin W. Pruitt (Cambridge, Massachusetts) |
| ABSTRACT | Methods of volumetric imaging of a three-dimensional matrix of nucleic acids within a cell is provided. An automated apparatus for sequencing and volumetric imaging of a three-dimensional matrix of nucleic acids is provided. |
| FILED | Wednesday, May 02, 2018 |
| APPL NO | 15/969118 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6841 (20130101) C12Q 1/6841 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2543/101 (20130101) C12Q 2543/101 (20130101) C12Q 2563/159 (20130101) C12Q 2563/159 (20130101) C12Q 2565/601 (20130101) C12Q 2565/601 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266951 | Pal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Uday B. Pal (Dover, Massachusetts); Soumendra N. Basu (Westwood, Massachusetts); Yihong Jiang (Boston, Massachusetts); Jiapeng Xu (Boston, Massachusetts) |
| ABSTRACT | A method of manufacturing silicon via a solid oxide membrane electrolysis process, including providing a crucible, providing a flux including silica within the crucible, providing a cathode in the crucible in electrical contact with the flux, and providing an anode disposed in the crucible spaced apart from the cathode and in electrical contact with the flux. The cathode includes a silicon-absorbing portion in fluid communication with the flux. The anode includes a solid oxide membrane around at least a portion of the anode. The method also includes generating an electrical potential between the cathode and anode sufficient to reduce silicon at an operating temperature, and cooling the silicon-absorbing portion to below the operating temperature, and precipitating out the silicon from the silicon-absorbing portion. The silicon-absorbing portion preferentially absorbs silicon, the silicon-absorbing portion is a liquid metal at the operating temperature, and the solid oxide membrane is permeable to oxygen. |
| FILED | Tuesday, November 26, 2013 |
| APPL NO | 14/353008 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/006 (20130101) Original (OR) Class C25B 9/08 (20130101) C25B 13/04 (20130101) Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 3/00 (20130101) C25C 7/005 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/182 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/546 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267754 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Yihua Bruce Yu (Baltimore, Maryland); Marc Taraban (Baltimore, Maryland); Yue Feng (Baltimore, Maryland) |
| ABSTRACT | The present invention generally relates to a method of using NMR relaxation rates (R2) of water molecules as an indicator of the extent of aggregation of biopharmaceutical formulations. The biopharmaceutical can be evaluated nondestructively without the vial or container being opened or protective seal compromised (i.e., broken). The method is applicable to all biopharmaceuticals and the water signal obtained by magnetic resonance relaxometry is very strong and sensitive because water is used as the solvent and is present in high (>90%) concentrations in every biopharmaceutical formulation. |
| FILED | Friday, April 11, 2014 |
| APPL NO | 14/780711 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/08 (20130101) Original (OR) Class G01N 33/15 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/448 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267763 | Zhong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Zhaohui Zhong (Ann Arbor, Michigan); Girish Kulkarni (Ann Arbor, Michigan); Karthik Reddy (Ann Arbor, Michigan); Xudong Fan (Saline, Michigan) |
| ABSTRACT | An improved sensing method is provided for rapid analyte detection. The method includes: applying an AC excitation signal to the channel region of the transistor; applying an AC drive signal to the transistor; delivering an analyte of interest to a channel region of a transistor; and monitoring a mixing current of the excitation signal and the drive signal through the transistor, where a change in the mixing current is indicative of the concentration of the analyte of interest. |
| FILED | Thursday, December 04, 2014 |
| APPL NO | 15/037809 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 53/025 (20130101) B01D 2257/70 (20130101) B01D 2257/556 (20130101) B01D 2257/2064 (20130101) B01D 2257/7022 (20130101) B01D 2257/7027 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4141 (20130101) Original (OR) Class G01N 27/4146 (20130101) G01N 27/4148 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267783 | Olson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Woods Hole Oceanographic Institution (Woods Hole, Massachusetts) |
| ASSIGNEE(S) | Woods Hole Oceanographic Institution (Woods Hole, Massachusetts) |
| INVENTOR(S) | Robert J. Olson (Cataumet, Massachusetts); Heidi M. Sosik (Falmouth, Massachusetts) |
| ABSTRACT | Submersible technology capable of sampling and evaluating suspended particulate materials, including living and dead organisms, is disclosed herein. In addition to fluorescent imaging and analysis, the invention provides automated cell staining, cell sorting, particulate concentration, and organism recovery and preservation. These new technologies may be incorporated into a traditional “fully vertical flow path” cytometer configuration most suitable for anchored or suspended stationary embodiments, or in a novel modularized “low relief” configuration, suitable for integration into or on a submersible aquatic vehicle or in other low clearance installations, where it is important to limit the vertical height of the device. |
| FILED | Tuesday, September 09, 2014 |
| APPL NO | 14/480871 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1404 (20130101) G01N 15/1459 (20130101) G01N 33/1886 (20130101) Original (OR) Class G01N 2015/0053 (20130101) G01N 2015/149 (20130101) G01N 2015/1413 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267786 | Yuan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Baohong Yuan (Arlington, Texas) |
| ABSTRACT | In one aspect, methods of imaging are described herein. In some embodiments, a method of imaging described herein comprises disposing a population of ultrasound-switchable fluorophores in a biological environment, the fluorophores having a switching threshold between an off state and an on state; exposing the biological environment to an ultrasound beam to create an activation region within the biological environment; switching at least one of the fluorophores within the activation region from the off state to the on state; exciting the at least one fluorophore with a beam of electromagnetic radiation; and detecting light emitted by the fluorophore. In some embodiments, the activation region has a maximum negative pressure and/or maximum temperature and the switching threshold of the at least one fluorophore is at least about 50 percent of the maximum negative pressure or at least about 50 percent of the maximum temperature of the activation region. |
| FILED | Thursday, January 23, 2014 |
| APPL NO | 14/162375 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0028 (20130101) A61K 49/0034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/5091 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267795 | Herr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Amy E. Herr (Oakland, California); Alex James Hughes (Berkeley, California); Elly Sinkala (Oakland, California); Todd A. Duncombe (Berkeley, California); Kevin A. Yamauchi (Berkeley, California); Julea Vlassakis (Berkeley, California); Chi-Chih Kang (Berkeley, California); Zhuchen Xu (Berkeley, California); Robert Lin (Berkeley, California) |
| ABSTRACT | Electrophoretic separation devices and methods for using the same are provided. Aspects of the devices include a polymeric separation medium that includes a plurality of microwells. Also provided are methods, systems and kits in which the subject devices find use. The devices and methods find use in a variety of different electrophoretic separation applications. |
| FILED | Thursday, March 06, 2014 |
| APPL NO | 14/650520 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44726 (20130101) G01N 27/44747 (20130101) G01N 27/44791 (20130101) G01N 33/561 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268114 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Hongwei Sun (Lexington, Massachusetts); Pengtao Wang (Lowell, Massachusetts); Junwei Su (Lowell, Massachusetts) |
| ABSTRACT | Quartz crystal microbalance resonators are described, as are methods of making them using micron sized pillar array of polymethyl methacrylate fabricated on a QCM surface using a nanoimprint lithography process. Their use in any applications, including for example gas and liquid sensors and biosensors as well as other measurement applications, is also discussed. |
| FILED | Monday, November 09, 2015 |
| APPL NO | 14/936566 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/022 (20130101) G01N 29/036 (20130101) G01N 29/4418 (20130101) G01N 29/4472 (20130101) G01N 2291/014 (20130101) G01N 2291/0257 (20130101) G01N 2291/0426 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class G03F 7/038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268661 | Tashman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Craig S. Tashman (Atlanta, Georgia); W. Keith Edwards (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Craig S. Tashman (Atlanta, Georgia); W. Keith Edwards (Atlanta, Georgia) |
| ABSTRACT | Review systems and methods facilitate active reading by providing a flexible environment in which users can examine documents. A review system can comprise a virtual workspace, a document view region, a preview region, and optional document objects. The virtual workspace can simulate a desktop or other physical workspace. The document view region can display a portion of an open document at a magnification sufficient for reading. The preview region can display the document at a magnification sufficient to enable the general layout of the entire document to be determined. The document objects can be created from the document through tools of the review system. These document objects can be independently moveable throughout the virtual workspace as needed to facilitate the user's active reading process. |
| FILED | Wednesday, March 16, 2011 |
| APPL NO | 13/876463 |
| ART UNIT | 2178 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 17/211 (20130101) Original (OR) Class G06F 17/241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268684 | Denkowski et al. |
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| FUNDED BY |
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| APPLICANT(S) | Amazon Technologies, Inc. (Seattle, Washington) |
| ASSIGNEE(S) | Amazon Technologies, Inc. (Seattle, Washington) |
| INVENTOR(S) | Michael Denkowski (Pittsburgh, Pennsylvania); Alon Lavie (Pittsburgh, Pennsylvania); Gregory Alan Hanneman (Pittsburgh, Pennsylvania); Matthew Ryan Fiorillo (Pittsburgh, Pennsylvania); Laura Josephine Kieras (Pittsburgh, Pennsylvania); Robert Thomas Olszewski (Pittsburgh, Pennsylvania); William Joseph Kaper (Pittsburgh, Pennsylvania); Alexandre Alexandrovich Klementiev (Berlin, Germany); Gavin Richard Jewell (Seattle, Washington) |
| ABSTRACT | Technologies are disclosed herein for statistical machine translation. In particular, the disclosed technologies include extensions to conventional machine translation pipelines: the use of multiple domain-specific and non-domain-specific dynamic language translation models and language models; cluster-based language models; and large-scale discriminative training. Incremental update technologies are also disclosed for use in updating a machine translation system in four areas: word alignment; translation modeling; language modeling; and parameter estimation. A mechanism is also disclosed for training and utilizing a runtime machine translation quality classifier for estimating the quality of machine translations without the benefit of reference translations. The runtime machine translation quality classifier is generated in a manner to offset imbalances in the number of training instances in various classes, and to assign a greater penalty to the misclassification of lower-quality translations as higher-quality translations than to misclassification of higher-quality translations as lower-quality translations. |
| FILED | Monday, September 28, 2015 |
| APPL NO | 14/868166 |
| ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 17/24 (20130101) G06F 17/289 (20130101) G06F 17/2818 (20130101) Original (OR) Class G06F 17/2854 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10269406 — Adaptive refreshing and read voltage control scheme for a memory device such as an FeDRAM
| US 10269406 | Bayram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Ismail Bayram (Pittsburgh, Pennsylvania); Yiran Chen (Pittsburgh, Pennsylvania) |
| ABSTRACT | A memory device, such as an FeDRAM device, includes a memory array including a plurality of rows, each row having a plurality of storage elements (e.g., FeFETs). The memory device further includes a plurality of refresh trigger circuits, each refresh trigger circuit being associated with a respective one of the rows. Each refresh trigger circuit is structured to produce an output signal indicative of an estimated degradation of a memory window of one or more of the storage elements of the associated one of the rows. The memory device also further includes control circuitry coupled to each of the refresh trigger circuits, wherein the control circuitry is structured and configured to determine whether to initiate a refresh of the storage elements of a particular one of the rows based on the output signal produced by the refresh trigger circuit associated with the particular one of the rows. |
| FILED | Monday, May 15, 2017 |
| APPL NO | 15/594807 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/223 (20130101) G11C 11/404 (20130101) G11C 11/406 (20130101) Original (OR) Class G11C 11/2273 (20130101) G11C 11/4091 (20130101) G11C 11/4096 (20130101) G11C 11/4099 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270536 | Almaiman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Ahmed Almaiman (Los Angeles, California); Alan E. Willner (Los Angeles, California); Yinwen Cao (Los Angeles, California); Morteza Ziyadi (Los Angeles, California) |
| ABSTRACT | Methods, systems, and apparatus for phase-sensitive regeneration of a signal without a phase-locked loop and using Brillouin amplification. The system for phase-sensitive regeneration includes a data channel, one or more pumps and a mixing stage. The one or more pumps are coupled with the data channel. The mixing stage is coupled with the data channel and is for processing a data signal that is combined with an output of the one or more pumps and idler or higher harmonic. The mixing stage is configured to amplify the idler or higher harmonic using Brillouin amplification in a Brillouin gain medium to keep the one or more pumps and the data channel phase-locked. |
| FILED | Monday, March 20, 2017 |
| APPL NO | 15/464180 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/556 (20130101) Original (OR) Class H04B 10/2507 (20130101) H04B 10/2916 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0331 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10271112 | Xiaoqi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Yin Xiaoqi (Pittsburgh, Pennsylvania); Sekar Vyas (Pittsburgh, Pennsylvania); Sinopoli Bruno (Pittsburgh, Pennsylvania) |
| ABSTRACT | A client video player device downloads video content from a video content delivery network as segments encoded at respective bitrates selected from distinct encoding bitrates. Bitrate adaptation logic within the client video player selects the appropriate bitrate segment in order to maximize user-perceived Quality-of-Experience. An optimization of this bitrate adaptation logic implementing model predictive control that maximizes the user-perceived Quality-of-Experience is presented. |
| FILED | Monday, March 28, 2016 |
| APPL NO | 15/082444 |
| ART UNIT | 2425 — Cable and Television |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 21/643 (20130101) H04N 21/6125 (20130101) H04N 21/6581 (20130101) H04N 21/6587 (20130101) H04N 21/8456 (20130101) Original (OR) Class H04N 21/23439 (20130101) H04N 21/44004 (20130101) H04N 21/44209 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10267263 | Lord et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Wesley K. Lord (South Glastonbury, Connecticut); Jesse M. Chandler (South Windsor, Connecticut); Gabriel L. Suciu (Glastonbury, Connecticut) |
| ABSTRACT | A gas turbine engine includes a core engine assembly including a compressor section communicating air to a combustor section where the air is mixed with fuel and ignited to generate a high-energy gas flow that is expanded through a turbine section. The turbine section is coupled to drive the compressor section. A propulsor section aft of the core engine is driven by the turbine section. An exhaust duct routing exhaust gases around the propulsor section. The exhaust duct includes an inlet forward of the propulsor section, an outlet aft of the turbine section and a passageway between the inlet and the outlet. An aircraft and exhaust duct are also disclosed. |
| FILED | Monday, August 08, 2016 |
| APPL NO | 15/230590 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/14 (20130101) B64D 33/02 (20130101) B64D 33/04 (20130101) B64D 35/04 (20130101) Jet-propulsion Plants F02K 1/52 (20130101) F02K 3/00 (20130101) Original (OR) Class F02K 3/062 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/312 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267694 | Rickman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Steven L. Rickman (League City, Texas); W. Lance Richards (Palmdale, California); Anthony Piazza (Palmdale, California); Eric L. Christiansen (Houston, Texas); Francisco Pena (Pasadena, California); Allen R. Parker, Jr. (Lancaster, California) |
| ABSTRACT | Various embodiments may provide a strain-sensing apparatus configured to be attached to a micrometeoroid and orbital debris (MMOD) shielding layer and data collection equipment in communication with the strain-sensing apparatus configured to detect an occurrence, a time, a location, and/or a severity of a MMOD strike on the MMOD shielding layer. The various embodiments may enable detection and/or location of potentially harmful MMOD strikes on both human occupied and unmanned spacecraft. |
| FILED | Friday, January 13, 2017 |
| APPL NO | 15/405606 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/246 (20130101) G01L 5/0052 (20130101) Original (OR) Class Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 11/083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268213 | Addona et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Brad M Addona (Huntsville, Alabama); James A Richard (Grant, Alabama); Richard J Joye (Huntsville, Alabama) |
| ABSTRACT | A check valve's housing has a valve disposed therein to open or close a flow path from the housing's inlet to its outlet based on a difference between pressures at the inlet and outlet. The valve includes a bellows, a poppet, and a spring. The poppet includes a hollow structure extending through the poppet's plate and terminating in a first open end disposed within the bellows, an annular flange between the second face of the poppet's plate and the housing's outlet, and an open-ended tube extending from the annular flange into the housing's outlet. The spring, disposed within the hollow tubular structure, positions the annular flange to seal the outlet when the pressure difference is less than a predetermined amount and compresses when the difference exceeds the predetermined amount wherein the annular flange is unsealed from the housing's outlet to open the flow path. |
| FILED | Friday, October 20, 2017 |
| APPL NO | 15/789736 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 15/026 (20130101) F16K 15/145 (20130101) F16K 17/0413 (20130101) F16K 31/1262 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 16/0619 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10268453 | Ong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of the NASA (Washington, District of Columbia) |
| INVENTOR(S) | James Ong (San Carlos, California); Emilio Remolina (Dublin, California); Peter I. Robinson (Palo Alto, California) |
| ABSTRACT | A method of communicating between one or more modules while executing a plan for a controlled system includes transmitting, by an execution manager, a request to a planner to create a plan in response to receiving a planning goals file. The method also includes transmitting, by the execution manager, the created plan to an adaptive controller for execution of the created plan within a controlled system, and receiving, by the execution manager, state estimates reporting diagnosis information of a controlled system. |
| FILED | Monday, March 07, 2016 |
| APPL NO | 15/063147 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/20 (20130101) Original (OR) Class G06F 8/33 (20130101) G06F 8/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10269463 — Nuclear thermionic avalanche cells with thermoelectric (NTAC-TE) generator in tandem mode
| US 10269463 | Choi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Sang Hyouk Choi (Poquoson, Virginia); Kunik Lee (Fairfax, Virginia) |
| ABSTRACT | Systems, methods, and devices of the various embodiments described herein enable an energy conversion system comprising a radioactive element for generating conduction-band electrons in an avalanche cell and generating heat, wherein the conduction-band electrons are provided to an anode to generate avalanche cell power, and the heat is provided to a thermoelectric generator to generate thermoelectric power. In an embodiment, the avalanche cell is irradiated with gamma rays, which excite electrons within the avalanche cell, generating a current. In an additional embodiment, the thermoelectric power and avalanche cell power can comprise a dual power system. |
| FILED | Wednesday, February 03, 2016 |
| APPL NO | 15/014608 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 1/04 (20130101) G21H 1/10 (20130101) G21H 1/103 (20130101) Original (OR) Class G21H 1/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10269526 | Martinez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Rafael A. Martinez (Redmond, Washington); John D. Williams (Fort Collins, Colorado); Joel A. Moritz, Jr. (Fort Collins, Colorado); Casey C. Farnell (Fort Collins, Colorado) |
| ABSTRACT | A miniature Hall current plasma source apparatus having magnetic shielding of the walls from ionized plasma, an integrated discharge channel and gas distributor, an instant-start hollow cathode mounted to the plasma source, and an externally mounted keeper, is described. The apparatus offers advantages over existing other Hall current plasma sources having similar power levels, including: lower mass, longer lifetime, lower part count including fewer power supplies, and the ability to be continuously adjustable to lower average power levels using pulsed operation and adjustment of the pulse duty cycle. The Hall current plasma source can provide propulsion for small spacecraft that either do not have sufficient power to accommodate a propulsion system or do not have available volume to incorporate the larger propulsion systems currently available. The present low-power Hall current plasma source can be used to provide energetic ions to assist the deposition of thin films in plasma processing applications. |
| FILED | Wednesday, February 21, 2018 |
| APPL NO | 15/901763 |
| ART UNIT | 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0075 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 27/143 (20130101) H01J 27/146 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10270347 | Marotta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| INVENTOR(S) | Joseph Marotta (Boonton, New Jersey); Paul Schwerman (Phoenix, Arizona); Serdar Tevfik Sozusen (Pine Brook, New Jersey) |
| ABSTRACT | A short-circuit protected power supply circuit includes a switching power supply and a short-circuit sense/protection circuit. The switching power supply includes a synchronous rectifier, an output inductor, and an output capacitor. The synchronous rectifier is responsive to a synchronous rectifier control signal to selectively switch between an ON state and an OFF state. The output inductor and output capacitor are electrically connected in series with each other and are electrically connected in parallel with the synchronous rectifier. An output node is located between the output inductor and output capacitor. The short-circuit sense/protection circuit is coupled to the output node and is configured, upon a voltage magnitude at the output node being less than a predetermined voltage magnitude, to cause the synchronous rectifier control signal to switch the synchronous rectifier to, or keep it in, the OFF state. The short-circuit sense/protection circuit is a Schmitt trigger or an error amplifier/comparator circuit. |
| FILED | Friday, August 18, 2017 |
| APPL NO | 15/680549 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/32 (20130101) H02M 3/157 (20130101) H02M 3/1588 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10264808 | McGarvey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Jeffery A. McGarvey (San Francisco, California); Robert M. Hnasko (Pinole, California); Larry H. Stanker (Livermore, California); Lisa A. Gorski (San Leandro, California) |
| ABSTRACT | The present invention relates to the use of phyllosphere-associated lactic acid bacteria that demonstrate inhibitory effects on the growth and maintenance of human pathogens, such as Salmonella enterica, on the surface of food products, particularly fresh fruits and vegetables. Particular strains of Enterococcus avium and Lactococcus lactis are described and detailed for their atypical pathogen-inhibiting phenotypes. |
| FILED | Tuesday, December 13, 2016 |
| APPL NO | 15/377186 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 7/154 (20130101) A23B 7/155 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 3/3463 (20130101) Original (OR) Class A23L 3/3571 (20130101) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2002/00 (20130101) Indexing Scheme Relating to Lactic or Propionic Acid Bacteria Used in Foodstuffs or Food Preparation A23Y 2240/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10265374 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MISSISSIPPI STATE UNIVERSITY (Starkville, Mississippi); THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | MISSISSIPPI STATE UNIVERSITY (Starkville, Mississippi); THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| INVENTOR(S) | James L. Smith (College Station, Texas); Stephen Pruett (Starkville, Mississippi); Frank Austin (Starkville, Mississippi); Shien Lu (Starkville, Mississippi); Ravichandran Akshaya (Bryan, Texas); Steven Laihing (College Station, Texas) |
| ABSTRACT | Disclosed are occidiofungin formulations and uses thereof for the treatment of proliferative disorders, such as cancer. Methods of producing the disclosed occidiofungin formulations are also provided. Further, methods of treating a subject with the formulations are provided. In some embodiments, the formulations include occidiofungin and one or more cyclodextrins. The formulations may optionally further comprise an additional chemotherapeutic agent for treating the proliferative disease, lipid vesicles, and/or aqueous solvents (including pharmaceutically acceptable buffers and/or exceipients). |
| FILED | Monday, September 14, 2015 |
| APPL NO | 15/510801 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 9/127 (20130101) A61K 31/724 (20130101) A61K 31/724 (20130101) A61K 38/12 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/40 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266814 | Mort et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (Stillwater, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents for Oklahoma State University (Stillwater, Oklahoma) |
| INVENTOR(S) | Andrew Mort (Stillwater, Oklahoma); Anamika Ray (Torrance, California); Sayali S. Saykhedkar (Hatboro, Pennsylvania); Rolf A. Prade (Stillwater, Oklahoma) |
| ABSTRACT | Compositions comprising glycosyl hydrolase enzymes are provided, as are methods for their use to depolymerize hemicellulose, cellulose, lignin and pectin in biomass in order to produce products such as simple sugars. The enzymes, isolated from Aspergillus nidulans and Phanerochaete chrysosporium, were characterized, and synergistic mixtures of the enzymes were produced and used to generate simple sugars from biomass without the need to pretreat the biomass before digestion. The enzyme blends generally comprise two or more enzymes, which may be from the same fungus or from two different fungi, and are used for efficient and cost effective complete degradation of lignocelluloses. Applications of this technology include biofuel production. |
| FILED | Tuesday, June 02, 2015 |
| APPL NO | 15/315484 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/24 (20130101) C12N 9/0083 (20130101) C12N 9/2402 (20130101) Original (OR) Class C12N 9/2437 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2203/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10266840 | Xin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia); Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
| INVENTOR(S) | Zhanguo Xin (Lubbock, Texas); Gloria B. Burow (Lubbock, Texas); Chad M Hayes (Lubbock, Texas); John J. Burke (Lubbock, Texas); Doreen Ware (Melville, New York); Yinping Jiao (Cold Spring Harbor, New York) |
| ABSTRACT | The present disclosure provides nucleic acids that confer a multi-seeded phenotype when expressed in plants and uses thereof. |
| FILED | Friday, March 11, 2016 |
| APPL NO | 15/067641 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/827 (20130101) C12N 15/8261 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10266765 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Wei Chen (Arlington, Texas); Lun Ma (Arlington, Texas) |
| ABSTRACT | This invention relates to new phosphor materials exhibiting luminescence and methods for their production. More particularly, the invention relates to new europium-doped zinc sulfide-manganese (ZnS:Mn,Eu) phosphors and use thereof for radiation detection. |
| FILED | Thursday, November 06, 2014 |
| APPL NO | 15/034124 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/773 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267739 | Dantus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Marcos Dantus (Okemos, Michigan); Marshall Thomas Bremer (Lansing, Michigan) |
| ABSTRACT | A laser system and method employing stimulated Raman scattering using a main laser pulse and a delayed replica reference pulse are provided. A further aspect calculates stimulated Raman loss and stimulated Raman gain from a reflected laser light scatter collected from a fabric or paper specimen. In another aspect, a laser system receives a low energy portion of a spectrum of main and reference laser pulses with a first photodetector, receives a higher energy portion of the spectrum of the main and reference pulses with a second photodetector, and uses a controller to determine a Raman active phonon transfer of energy manifested as an increase in the reflected laser scatter in a lower energy portion of the spectrum and a decrease in a higher energy portion of the spectrum. In yet another aspect, the controller automatically determines if a hazardous particle or substance such as an explosive, is present on a specimen. |
| FILED | Thursday, July 31, 2014 |
| APPL NO | 14/907992 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/36 (20130101) G01J 3/44 (20130101) G01J 3/0224 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 33/227 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267837 | Bassen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Howard Bassen (Chevy Chase, Maryland); Gonzalo Mendoza (Sterling, Virginia); Amir Razjouyan (Annandale, Virginia); Mohammed Eslami (Gaithersburg, Maryland); Negin Shahshahan (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure is directed to an apparatus for detecting low level pulses of millimeter wave electromagnetic radiation, such as by detecting the presence of weak electromagnetic emissions inside or around an electromagnetic radiation-emitting device, such as a millimeter wave scanner. The apparatus may also be used to assess such emissions and display a graphical and numerical indication of a sensed level of energy density. A hand-held portable apparatus for detecting low levels of electromagnetic radiation as well as a method for detecting low levels of electromagnetic radiation are also provided. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/031353 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/0878 (20130101) Original (OR) Class G01R 33/285 (20130101) G01R 33/287 (20130101) G01R 33/383 (20130101) G01R 33/3808 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267904 | Barber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey Brian Barber (Vineland, New Jersey); Peter Roland Smith (Westfield, New Jersey); James Christopher Weatherall (Atlantic City, New Jersey); Barry Thomas Smith (Egg Harbor City, New Jersey) |
| ABSTRACT | The present disclosure is directed to an artificial skin including: a radar absorbing layer; a conductive layer comprising at least one material selected from the group consisting of a semiconductive oxide deposited onto a substrate and an electrically conductive polymer, wherein the substrate is in contact with the radar absorbing layer, and wherein the artificial skin has a reflection coefficient substantially equal to a human skin reflection coefficient, the human skin reflection coefficient being determined at an electromagnetic radiation frequency ranging from 1-500 GHz. A human phantom composed of the artificial skin and methods of using the human phantom are also disclosed. |
| FILED | Wednesday, August 08, 2018 |
| APPL NO | 16/058522 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/522 (20130101) G01J 2005/0077 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/497 (20130101) Original (OR) Class G01S 7/52004 (20130101) G01S 13/89 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10268968 | Abraham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | David W. Abraham (Croton, New York); Josephine B. Chang (Ellicott City, Maryland); Jay M. Gambetta (Yorktown Heights, New York) |
| ABSTRACT | A technique relates to a superconducting qubit. A Josephson junction includes a first superconductor and a second superconductor formed on a non-superconducting metal. A capacitor is coupled in parallel with the Josephson junction. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 15/813441 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Original (OR) Class Static Stores G11C 11/44 (20130101) G11C 16/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) H01L 39/025 (20130101) H01L 39/045 (20130101) H01L 39/223 (20130101) H01L 39/2493 (20130101) Pulse Technique H03K 19/1952 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10269580 | Armstrong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Christine Armstrong (Stamford, New York); Matthew W. Copel (Yorktown Heights, New York); Yu Luo (Hopewell Junction, New York); Paul M. Solomon (Yorktown Heights, New York) |
| ABSTRACT | A subtractive forming method that includes providing a material stack including a samarium and selenium containing layer and an aluminum containing layer in direct contact with the samarium and selenium containing layer. The samarium component of the samarium and selenium containing layer of the exposed portion of the material stack is etched with an etch chemistry comprising citric acid and hydrogen peroxide that is selective to the aluminum containing layer. The hydrogen peroxide reacts with the aluminum containing layer to provide an oxide etch protectant surface on the aluminum containing layer, and the citric acid etches samarium selectively to the oxide etch protectant surface. Thereafter, a remaining selenium component of is removed by elevating a temperature of the selenium component. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804394 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0256 (20130101) H01L 21/0262 (20130101) H01L 21/32134 (20130101) Original (OR) Class H01L 41/16 (20130101) H01L 41/39 (20130101) H01L 41/187 (20130101) H01L 41/316 (20130101) H01L 41/332 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10267058 | Irwin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Donald E. Irwin (Fredricksburg, Virginia); Michael L. Spears (Chantilly, Virginia); Robert Dalton (Greenville, South Carolina) |
| ABSTRACT | Described herein is locking apparatus, method for making a locking apparatus, and method for mounting a locking apparatus to the door of a personal storage container. The locking apparatus may include a threaded portion having deformed threads and a lock body shape to fit a restrictive mounting hole. |
| FILED | Friday, October 06, 2017 |
| APPL NO | 15/726798 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 55/14 (20130101) Locks; Accessories Therefor; Handcuffs E05B 9/04 (20130101) Original (OR) Class E05B 15/16 (20130101) E05B 17/04 (20130101) E05B 27/0003 (20130101) E05B 65/006 (20130101) E05B 65/52 (20130101) Bolts or Fastening Devices for Wings, Specially for Doors or Windows E05C 3/042 (20130101) Technical Subjects Covered by Former US Classification Y10T 70/5093 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10267065 | Matthews et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Services (Washington, District of Columbia) |
| INVENTOR(S) | James Edmund Matthews (Bowie, Maryland); Joram Shenhar (Fairfax, Virginia); Terry Martin Gingell (Spotsylvania, Virginia); Donald Eugene Irwin (Fredericksburg, Virginia); William Albert Tartal (Baltimore, Maryland) |
| ABSTRACT | Receptacle locking devices are disclosed. A receptacle locking device having a contact arm and a pivoting feature can be pivoted from a first, unlocked position to a second, locked position, wherein the contact arm prevents opening of the receptacle door when the locking device is in the second, locked position. |
| FILED | Wednesday, August 16, 2017 |
| APPL NO | 15/678872 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Household or Table Equipment A47G 29/1245 (20130101) Locks; Accessories Therefor; Handcuffs E05B 65/0071 (20130101) E05B 65/0888 (20130101) Original (OR) Class E05B 65/0894 (20130101) Bolts or Fastening Devices for Wings, Specially for Doors or Windows E05C 19/18 (20130101) E05C 19/184 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10265699 | Liddle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Commerce (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| INVENTOR(S) | J. Alexander Liddle (Rockville, Maryland); Samuel M. Stavis (North Potomac, Maryland); Glenn E. Holland (Rockville, Maryland) |
| ABSTRACT | A fluid sampler includes: a sample cell that includes: a substrate comprising: a first port; a second port in fluid communication with the first port; a viewing reservoir in fluid communication with the first port and the second port and that receives the fluid from the first port and communicates the fluid to the second port, the viewing reservoir including: a first view membrane; a second view membrane; and a pillar interposed between the first view membrane and second view membrane, the pillar separating the first view membrane from the second view membrane at a substantially constant separation distance such that a volume of the viewing reservoir is substantially constant and invariable with respect to a temperature and invariable with respect to a pressure to which the sample cell is subjected. |
| FILED | Thursday, June 01, 2017 |
| APPL NO | 15/611564 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 3/502707 (20130101) B01L 9/00 (20130101) B01L 2200/12 (20130101) B01L 2300/06 (20130101) B01L 2300/046 (20130101) B01L 2300/0609 (20130101) B01L 2300/0681 (20130101) B01L 2300/0867 (20130101) B01L 2300/0887 (20130101) B01L 2300/0896 (20130101) B01L 2400/0415 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 23/02 (20130101) G01N 23/04 (20130101) G01N 23/2251 (20130101) G01N 27/4473 (20130101) G01N 27/44791 (20130101) G01N 35/0099 (20130101) G01N 2223/307 (20130101) G01N 2223/418 (20130101) G01N 2223/638 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/16 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/3065 (20130101) H01L 21/31122 (20130101) H01L 21/47573 (20130101) H01L 2924/1067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Treasury (TREASURY)
| US 10266892 | Esfandyarpour et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GenapSys, Inc. (Redwood City, California) |
| ASSIGNEE(S) | GENAPSYS, INC. (Redwood City, California) |
| INVENTOR(S) | Hesaam Esfandyarpour (Redwood City, California); Kosar Baghbani Parizi (Redwood City, California); Mark F. Oldham (Emerald Hills, California); Eric S. Nordman (Palo Alto, California); Richard T. Reel (Hayward, California); Susanne Baumhueter (Redwood City, California); Cheryl Heiner (La Honda, California); Frank Lee (Irvine, California) |
| ABSTRACT | The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices. |
| FILED | Wednesday, June 13, 2018 |
| APPL NO | 16/007969 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 2527/119 (20130101) C12Q 2527/119 (20130101) C12Q 2549/126 (20130101) C12Q 2563/116 (20130101) C12Q 2563/116 (20130101) C12Q 2565/607 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/327 (20130101) G01N 33/5438 (20130101) G01N 33/54313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 10265930 | Aston et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Huntington Beach, California) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Richard W. Aston (Brea, California); Anna Maria Tomzynska (Seal Beach, California); Eric S. Mindock (Playa del Rey, California) |
| ABSTRACT | Protective blankets include a plurality of sheets of material operatively coupled together to define the protective blanket. The plurality of sheets includes at least one sheet composed of carbon nanotube reinforced composite material and at least one sheet composed of a different material. Methods of assembling protective blankets include layering the plurality of sheets and operatively coupling together the plurality of sheets. Spacecraft include a body and a protective blanket operatively coupled to the body. Methods of assembling spacecraft include coupling a protective blanket to the body of a spacecraft. |
| FILED | Monday, January 12, 2015 |
| APPL NO | 14/595019 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/06 (20130101) B32B 5/024 (20130101) B32B 5/26 (20130101) Original (OR) Class B32B 5/028 (20130101) B32B 15/14 (20130101) B32B 37/16 (20130101) B32B 2260/021 (20130101) B32B 2260/023 (20130101) B32B 2260/046 (20130101) B32B 2262/02 (20130101) B32B 2262/106 (20130101) B32B 2262/0269 (20130101) B32B 2264/108 (20130101) B32B 2307/212 (20130101) B32B 2307/304 (20130101) B32B 2307/558 (20130101) B32B 2571/00 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/52 (20130101) B64G 1/56 (20130101) B64G 1/546 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10265458 | Young et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advent Access Pte. Ltd. (Singapore, Singapore) |
| ASSIGNEE(S) | ADVENT ACCESS PTE. LTD. (Singapore, Singapore) |
| INVENTOR(S) | Nathaniel P. Young (Salt Lake City, Utah); Mark A. Crawford (Sandy, Utah) |
| ABSTRACT | A vascular access port can include a base that can be attached to a vessel and a body extending away from the base in at least a vertical direction. A height of the body in the vertical direction can be sufficiently small such that the entire port can be implanted subcutaneously in a patient. The port can include a guidance passageway that is at least partially defined by the body and can direct an access device into a vessel of a patient when the port is attached to the vessel. In some arrangements, the guidance passageway includes a funnel region that decreases in size from a proximal end of the guidance passageway toward a distal end of the guidance passageway that defines an opening through the bottom surface of the port. |
| FILED | Monday, November 09, 2015 |
| APPL NO | 14/936567 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0057 (20130101) A61B 17/3423 (20130101) A61B 2017/3425 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3653 (20130101) A61M 1/3659 (20140204) A61M 1/3661 (20140204) Original (OR) Class A61M 39/0208 (20130101) A61M 2205/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10267786 | Yuan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Baohong Yuan (Arlington, Texas) |
| ABSTRACT | In one aspect, methods of imaging are described herein. In some embodiments, a method of imaging described herein comprises disposing a population of ultrasound-switchable fluorophores in a biological environment, the fluorophores having a switching threshold between an off state and an on state; exposing the biological environment to an ultrasound beam to create an activation region within the biological environment; switching at least one of the fluorophores within the activation region from the off state to the on state; exciting the at least one fluorophore with a beam of electromagnetic radiation; and detecting light emitted by the fluorophore. In some embodiments, the activation region has a maximum negative pressure and/or maximum temperature and the switching threshold of the at least one fluorophore is at least about 50 percent of the maximum negative pressure or at least about 50 percent of the maximum temperature of the activation region. |
| FILED | Thursday, January 23, 2014 |
| APPL NO | 14/162375 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0028 (20130101) A61K 49/0034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/5091 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
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How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, April 23, 2019.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
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HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190423.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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