FedInvent™ Patents
Patent Details for Tuesday, April 30, 2019
This page was updated on Monday, March 27, 2023 at 05:47 AM GMT
Department of Health and Human Services (HHS)
US 10271541 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Velico Medical, Inc (Beverly, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Qiyong Peter Liu (Newton, Massachusetts); Karin Hoffmeister (Chestnut Hill, Mississippi); Robert Sackstein (Sudbury, Massachusetts) |
ABSTRACT | The present invention relates to a platelet additive solution (PAS) having an amount of one or more β-galactosidase inhibitors with or without an amount of one or more sialidase inhibitors, and optionally one or more glycan-modifying agents; and one or more of PAS components that include a salt, a citrate source, a carbon source, or any combination thereof. |
FILED | Friday, February 17, 2017 |
APPL NO | 15/436715 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Original (OR) Class Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10271725 | Buckland et al. |
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APPLICANT(S) | Bioptigen, Inc. (Morrisville, North Carolina) |
ASSIGNEE(S) | Bioptigen, Inc. (Morrisville, North Carolina) |
INVENTOR(S) | Eric L. Buckland (Hickory, North Carolina); Andrew Murnan (Saratoga Springs, New York); Nestor O. Farmiga (Rochester, New York); Robert H. Hart (Cary, North Carolina); Christopher Saxer (Chapel Hill, North Carolina) |
ABSTRACT | Optical coherence tomography (OCT) imaging systems are provided including a source of broadband optical radiation coupled to a sample arm of the OCT imaging system; a beam shaping optical assembly in the sample arm, the beam shaping optical assembly being configured to receive optical radiation from the source as a beam of optical radiation and to shape the spatial profile of the beam of optical radiation; a scan mirror assembly coupled to the beam shaping optical assembly; and objective lens assembly coupled to the beam shaping optical assembly. The beam shaping optical assembly includes a lens assembly configured to change a NA of the OCT system without changing a focus; to change a focus of the OCT system without changing a NA of the system; or to change both the NA and the focus of the OCT system responsive to a control input. |
FILED | Thursday, November 30, 2017 |
APPL NO | 15/826966 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) Original (OR) Class A61B 3/1025 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02038 (20130101) G01B 9/02042 (20130101) G01B 9/02091 (20130101) Optical Elements, Systems, or Apparatus G02B 19/0014 (20130101) G02B 23/2407 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10271744 | Narayan et al. |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia); Topera, Inc. (Menlo Park, California) |
INVENTOR(S) | Sanjiv Narayan (La Jolla, California); Carey Robert Briggs (La Jolla, California); Ruchir Sehra (Scottsdale, Arizona) |
ABSTRACT | In a system and method for identifying a driver of a source associated with a heart rhythm disorder, data are accessed from a plurality of sensors representing biological activity in the heart. A first region and a second region of the heart, which comprise the source of the heart rhythm disorder, are identified. If the first region of the heart has repeating centrifugal activation and controls the second region of the heart for at least a predetermined number of beats, the first region is identified as controlling the source of the heart rhythm disorder. |
FILED | Friday, April 22, 2016 |
APPL NO | 15/136268 |
ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0002 (20130101) A61B 5/0006 (20130101) A61B 5/044 (20130101) A61B 5/046 (20130101) A61B 5/0422 (20130101) A61B 5/0452 (20130101) A61B 5/02405 (20130101) Original (OR) Class A61B 5/02444 (20130101) A61B 5/04012 (20130101) A61B 5/6852 (20130101) A61B 2560/0475 (20130101) A61B 2562/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10271780 | Van Duyne et al. |
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APPLICANT(S) | Richard P. Van Duyne (Wilmette, Illinois); Matthew R. Glucksberg (Chicago, Illinois); Joseph T. Walsh, Jr. (Evanston, Illinois); Jonathan M. Yuen (Chicago, Illinois); Nilam C. Shah (Chicago, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Richard P. Van Duyne (Wilmette, Illinois); Matthew R. Glucksberg (Chicago, Illinois); Joseph T. Walsh, Jr. (Evanston, Illinois); Jonathan M. Yuen (Chicago, Illinois); Nilam C. Shah (Chicago, Illinois) |
ABSTRACT | The present invention provides systems and methods employing a surface enhanced Raman biosensor and sensing devices for collecting spatially offset Raman spectra from the biosensor. In certain embodiments, the present invention provides systems and methods for quantifying the concentration of an analyte in a subject, and/or identifying the presence or absence of an analyte in a subject, from a plurality of spatially offset Raman spectra generated from a surface enhanced Raman biosensor implanted in a subject. |
FILED | Wednesday, November 23, 2011 |
APPL NO | 13/303815 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1455 (20130101) A61B 5/1459 (20130101) Original (OR) Class A61B 5/14532 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10271786 | Narayan et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia); Topera, Inc. (Menlo Park, California) |
INVENTOR(S) | Sanjiv Narayan (La Jolla, California); Carey Robert Briggs (La Jolla, California) |
ABSTRACT | Reconstruction of cardiac information associated with a heart rhythm disorder includes accessing a plurality of neighboring cardiac signals and eliminating far-field activations from the neighboring cardiac signals using one or more divergence criteria that define local activations, where the divergence criteria is associated with divergence among the plurality of neighboring cardiac signals. The local activations in the plurality of neighboring cardiac signals may be used to construct a clinical representation of the heart rhythm disorder. |
FILED | Thursday, July 07, 2016 |
APPL NO | 15/204455 |
ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0422 (20130101) A61B 5/0452 (20130101) A61B 5/02405 (20130101) A61B 5/04012 (20130101) A61B 5/4836 (20130101) Original (OR) Class A61B 5/7203 (20130101) A61B 5/7239 (20130101) A61B 5/7278 (20130101) A61B 2562/046 (20130101) A61B 2562/0209 (20130101) Electric Digital Data Processing G06F 19/3418 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10271891 | Curley |
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APPLICANT(S) | Thermedical, Inc. (Waltham, Massachusetts) |
ASSIGNEE(S) | Thermedical, Inc. (Waltham, Massachusetts) |
INVENTOR(S) | Michael G. Curley (Weston, Massachusetts) |
ABSTRACT | Devices, systems, and methods for degassing fluid prior to applying fluid to a treatment site during ablation therapy are provided. In one embodiment, an ablation system can include an elongate body, an ablation element, a heating assembly, and a fluid source. Fluid in the fluid source can be at least partially degassed prior to being provided as part of the system, or, in some embodiments, a degassing apparatus can be provided that can be configured to degas fluid within the system prior to applying the fluid to the treatment site. The degassing apparatus can include one or more gas-permeable and fluid-impermeable tubes disposed therein, which can allow gas to be removed from fluid passing through the apparatus. Other exemplary devices, systems, and methods are also provided. |
FILED | Friday, August 14, 2015 |
APPL NO | 14/826563 |
ART UNIT | 3739 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/04 (20130101) Original (OR) Class A61B 18/16 (20130101) A61B 18/082 (20130101) A61B 18/1477 (20130101) A61B 2017/00526 (20130101) A61B 2018/00029 (20130101) A61B 2018/00041 (20130101) A61B 2018/046 (20130101) A61B 2018/162 (20130101) A61B 2018/00577 (20130101) A61B 2018/00642 (20130101) A61B 2018/00773 (20130101) A61B 2018/00791 (20130101) A61B 2018/00797 (20130101) A61B 2018/00809 (20130101) A61B 2018/00821 (20130101) A61B 2018/1425 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 17/03 (20130101) F04B 19/22 (20130101) F04B 43/04 (20130101) F04B 49/06 (20130101) Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps F04C 2270/041 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49016 (20150115) Y10T 29/49085 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10271991 | Knox et al. |
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APPLICANT(S) | University of Rochester (Rochester, New York) |
ASSIGNEE(S) | University of Rochester (Rochester, New York) |
INVENTOR(S) | Wayne H. Knox (Pittsford, New York); Krystel R. Huxlin (Rush, New York) |
ABSTRACT | A method for providing vision correction to a patient. The method includes: (a) measuring the degree of vision correction needed by the patient and determining the location and shape of refractive structures that need to be positioned within the cornea to partially correct a patient's vision; (b) directing and focusing femtosecond laser pulses in the blue spectral region within the cornea at an intensity high enough to change the refractive index of the cornea within a focal region, but not high enough to damage the cornea or to affect cornea tissue outside of the focal region; and (c) scanning the laser pulses across a volume of the cornea or the lens to provide the focal region with refractive structures in the cornea or the lens. Again, the refractive structures are characterized by a change in refractive index, and exhibit little or no scattering loss. |
FILED | Wednesday, October 19, 2016 |
APPL NO | 15/297560 |
ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/008 (20130101) A61F 9/00827 (20130101) A61F 9/00829 (20130101) Original (OR) Class A61F 2009/0087 (20130101) A61F 2009/00842 (20130101) A61F 2009/00851 (20130101) A61F 2009/00872 (20130101) A61F 2009/00897 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272019 | Deng et al. |
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APPLICANT(S) | Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Yang Deng (New Haven, Connecticut); Asiri Ediriwickrema (Cary, North Carolina); William M. Saltzman (New Haven, Connecticut) |
ABSTRACT | Core-shell particles have a hydrophobic core and a shell formed of or containing hyperbranched polyglycerol (HPG). The HPG can be covalently bound to the one or more materials that form the core or coated thereon. The HPG coating can be modified to adjust the properties of the particles. For example, unmodified HPG coatings impart stealth properties to the particles which resist non-specific protein absorption. Alternatively, the hydroxyl groups on the HPG coating can be chemically modified to form functional groups that react with functional groups on tissue or otherwise interact with tissue to adhere the particles to the tissue, cells, or extracellular materials, such as proteins. Such functional groups include, but not limited to, aldehydes, amines, and O-substituted oximes. Topical formulation for application to the skin contain these HPG coated nanoparticles. In some embodiments, the particles include therapeutic, diagnostic, nutraceutical, and/or prophylactic agents such as those used as sunblock compositions. |
FILED | Monday, May 11, 2015 |
APPL NO | 15/309733 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/90 (20130101) A61K 8/0241 (20130101) Original (OR) Class A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 9/1647 (20130101) A61K 9/5031 (20130101) A61K 9/5146 (20130101) A61K 9/5153 (20130101) A61K 31/427 (20130101) A61K 31/4178 (20130101) A61K 31/4745 (20130101) A61K 47/34 (20130101) A61K 2800/412 (20130101) A61K 2800/413 (20130101) A61K 2800/624 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/04 (20130101) Acyclic or Carbocyclic Compounds C07C 59/06 (20130101) C07C 59/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272033 | Bronshtein |
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FUNDED BY |
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APPLICANT(S) | Victor Bronshtein (San Diego, California) |
ASSIGNEE(S) | UNIVERSAL STABILIZATION TECHNOLOGIES, INC (San Diego, California) |
INVENTOR(S) | Victor Bronshtein (San Diego, California) |
ABSTRACT | Biopharmaceuticals, such as vaccine agents and probiotics, are encapsulated in carbohydrate-glass particles and embedded in an amorphous polymer substrate to produce polymeric compositions containing ambient-temperature stable biopharmaceuticals for syringeless administration to patients such as via dissolvable films, micro-needle patches and similar medical delivery devices. The amorphous polymer substrate is soluble in both water and volatile organic solvents, yet the carbohydrate-glass particles are insoluble in organic solvents. A method for formulation of the polymeric compositions containing ambient-temperature stable biopharmaceuticals includes combining biopharmaceuticals encapsulated in carbohydrate-glass particles with polymer in organic solvent and evaporating the organic solvent to yield a water soluble polymeric composition containing ambient-temperature stable biopharmaceuticals. |
FILED | Friday, May 30, 2014 |
APPL NO | 14/292809 |
ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) Original (OR) Class A61K 35/741 (20130101) Technologies for Adaptation to Climate Change Y02A 50/387 (20180101) Y02A 50/406 (20180101) Y02A 50/465 (20180101) Y02A 50/471 (20180101) Y02A 50/483 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272039 | Jin et al. |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Haksong Jin (McLean, Virginia); George Grimes (Rockville, Maryland); Deborah Sperling (Woodbine, Maryland); Gopal Potti (Gaithersburg, Maryland); Caterina P. Minniti (Chevy Chase, Maryland); Gregory J. Kato (Woodbine, Maryland) |
ABSTRACT | A sodium nitrite formulation for topical administration is described. The formulation includes an aqueous solution of non-acidified sodium nitrite dispersed in a white petrolatum ointment. The concentration of sodium nitrite in the formulation is about 0.5% to about 3.0% by weight. To prepare the formulation, non-acidified sodium nitrite is completely dissolved in a small quantity of water, sterile filtered and dispersed in white petrolatum ointment. |
FILED | Tuesday, November 10, 2015 |
APPL NO | 15/525557 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) Original (OR) Class A61K 9/0014 (20130101) A61K 33/00 (20130101) A61K 45/06 (20130101) A61K 47/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272050 | Farokhzad et al. |
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APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Omid C. Farokhzad (Waban, Massachusetts); Won Il Choi (Cambridge, Massachusetts); Ulrich von Andrian (Chestnut Hill, Massachusetts); Nazila Kamaly (Boston, Massachusetts) |
ABSTRACT | This disclosure relates to nanoparticles, compositions, methods of making, and methods of use thereof. |
FILED | Wednesday, October 14, 2015 |
APPL NO | 15/519052 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5115 (20130101) A61K 9/5146 (20130101) Original (OR) Class A61K 9/5153 (20130101) A61K 9/5192 (20130101) A61K 31/7088 (20130101) A61K 38/27 (20130101) A61K 38/28 (20130101) A61K 38/1816 (20130101) A61K 38/2013 (20130101) A61K 38/2066 (20130101) A61K 47/02 (20130101) Technologies for Adaptation to Climate Change Y02A 50/401 (20180101) Y02A 50/475 (20180101) Y02A 50/481 (20180101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/906 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272055 | Potter et al. |
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APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | David A. Potter (Minneapolis, Minnesota); Zhijun Guo (Minneapolis, Minnesota); Elizabeth Amin (Minneapolis, Minnesota); Gunda Georg (Minneapolis, Minnesota); Tom Poulos (Irvine, California); Irina Sevrioukova (Irvine, California) |
ABSTRACT | Biguanide compounds and salts thereof are disclosed. Also disclosed are pharmaceutical compositions and therapeutic methods for treating certain diseases including cancer such as breast cancer. |
FILED | Friday, March 06, 2015 |
APPL NO | 14/641122 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/155 (20130101) Original (OR) Class A61K 31/155 (20130101) A61K 31/417 (20130101) A61K 31/417 (20130101) A61K 31/426 (20130101) A61K 31/426 (20130101) A61K 31/4409 (20130101) A61K 31/4409 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 279/26 (20130101) Heterocyclic Compounds C07D 213/36 (20130101) C07D 233/64 (20130101) C07D 277/28 (20130101) Peptides C07K 2299/00 (20130101) C07K 2319/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0073 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272056 | Chiaramello et al. |
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APPLICANT(S) | The George Washington University a Congressionally Chartered Not-for-Profit Corporation (Washington, District of Columbia) |
ASSIGNEE(S) | The George Washington University, A Congressionally Chartered Not-for-Profit Corporation (Washington, District of Columbia) |
INVENTOR(S) | Anne Chiaramello (Washington, District of Columbia); Martine Uittenbogaard (Washington, District of Columbia) |
ABSTRACT | The present application relates to methods of treating a subject with a disease or disorder associated with a mitochondrial deficit, comprising: determining at least one of a type or degree of the mitochondrial deficit in the subject; and administering an amount of a butyrate compound to the subject based at least partially on the determining step so as to promote Adenosine triphosphate (ATP) production in the subject as well as to methods of screening for compounds that restore cellular mitochondrial activity. |
FILED | Friday, April 01, 2016 |
APPL NO | 15/548233 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) Original (OR) Class A61K 31/19 (20130101) A61K 31/225 (20130101) A61K 31/225 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5079 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272069 | Burkin et al. |
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APPLICANT(S) | BOARD OF REGENTS OF NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF UNIVERSITY OF NEVADA, RENO (Reno, Nevada) |
ASSIGNEE(S) | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (Reno, Nevada) |
INVENTOR(S) | Dean Burkin (Sparks, Nevada); Ryan Wuebbles (Sparks, Nevada) |
ABSTRACT | Disclosed herein are α7β1 integrin modulatory agents and methods of using such to treat conditions associated with decreased α7β1 integrin expression or activity, including muscular dystrophy. In one example, methods for treating a subject with muscular dystrophy are disclosed. The methods include administering an effective amount of an α7β1 integrin modulatory agent to the subject with muscular dystrophy, wherein the α7β1 integrin modulatory agent increases α7β1 integrin expression or activity as compared to α7β1 integrin expression or activity prior to treatment, thereby treating the subject with muscular dystrophy. Also disclosed are methods of enhancing muscle regeneration, repair, or maintenance in a subject and methods of enhancing α7β1 integrin expression by use of the disclosed α7β1 integrin modulatory agents. Methods of prospectively preventing or reducing muscle injury or damage in a subject are also disclosed. |
FILED | Friday, December 16, 2016 |
APPL NO | 15/382448 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) Original (OR) Class A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272080 | Bhide et al. |
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APPLICANT(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida); The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida); The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Pradeep G. Bhide (Tallahassee, Florida); Jinmin Zhu (Tallahassee, Florida); Joseph Biederman (Brookline, Massachusetts); Thomas J. Spencer (Carlisle, Massachusetts) |
ABSTRACT | Working memory deficits are treated and working memory is improved with a composition that comprises a therapeutically effective amount of one or more respective selective dopamine D4 receptor agonists and/or pharmaceutically acceptable analogs, salts or hydrates of the respective one or more selective dopamine D4 receptor agonists. This composition can be administered to a subject to improve the subject's working memory. |
FILED | Friday, September 12, 2014 |
APPL NO | 15/021304 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/08 (20130101) A61K 9/14 (20130101) A61K 9/0019 (20130101) A61K 9/20 (20130101) A61K 9/48 (20130101) A61K 9/0053 (20130101) A61K 9/4825 (20130101) A61K 31/495 (20130101) Original (OR) Class A61K 31/4545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272093 | Cotman et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | Regents of the University of California (Oakland, California) |
INVENTOR(S) | Carl W. Cotman (Santa Ana, California); Larry E. Overman (Corona del Mar, California); Shikha Snigdha (Long Beach, California) |
ABSTRACT | Use of H3K9me3 modulation for enhancing cognitive function and treating anxiety related disorders is presented. A composition is administered to the subject comprising a therapeutically effective amount of a SUV39H1 inhibitor comprising analogs of ETP69. The therapeutically effective amount is effective in treating cognitive dysfunction in aging and age-related disorders. |
FILED | Friday, June 03, 2016 |
APPL NO | 15/580419 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/202 (20130101) A61K 31/522 (20130101) A61K 31/548 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/22 (20180101) Heterocyclic Compounds C07D 513/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272096 | Berns et al. |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Michael W. Berns (Irvine, California); Ryan M. Spitler (Costa Mesa, California); Gerard Boss (La Jolla, California) |
ABSTRACT | The invention generally relates to methods for treating and/or reducing the severity of a wound in a subject. Provided are wound therapies combining low level light therapy (LLLT) and a nitric oxide (NO) donor to treat and/or reduce the severity of the wound. The LLLT and NO donor may be administered concurrently or sequentially. Also provided are wound treatment systems and kits including a light source and a NO donor, which are administered to a wounded subject. Further provided are pharmaceutical compositions that comprise a NO donor and are formulated to be administered in conjunction with LLLT. |
FILED | Friday, June 06, 2014 |
APPL NO | 14/894984 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/12 (20130101) A61K 9/0014 (20130101) A61K 31/555 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0613 (20130101) A61N 5/0616 (20130101) A61N 2005/067 (20130101) A61N 2005/0651 (20130101) A61N 2005/0659 (20130101) A61N 2005/0662 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272098 | Zhong et al. |
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FUNDED BY |
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APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Yinghui Zhong (Bala Cynwyd, Pennsylvania); Zhiling Zhang (Philadelphia, Pennsylvania) |
ABSTRACT | The present invention provides drug delivery compositions that allow for immediate and/or sustained release of a therapeutic agent contained within the system. The present invention also provides drug delivery compositions that preserve the stability of the therapeutic agent contained within during the sustained release. The present invention further provides a method of treating, ameliorating, or preventing an inflammation-related disease or disorder in a subject using the compositions of the invention. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/773883 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 9/0024 (20130101) A61K 9/141 (20130101) A61K 31/65 (20130101) Original (OR) Class A61K 31/496 (20130101) A61K 31/704 (20130101) A61K 47/52 (20170801) A61K 47/58 (20170801) A61K 47/59 (20170801) A61K 47/60 (20170801) A61K 47/61 (20170801) A61K 47/645 (20170801) A61K 47/6903 (20170801) A61K 47/6921 (20170801) A61K 47/6927 (20170801) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272099 | Hergenrother et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas); The Board of Trustees of the University of Illinois. (Urbana, Illinois) |
INVENTOR(S) | Paul J. Hergenrother (Champaign, Illinois); David A. Boothman (Dallas, Texas); Joseph S. Bair (Mullica Hill, New Jersey); Lifen Cao (Dallas, Texas); Jinming Gao (Plano, Texas); Xiumei Huang (Dallas, Texas); Xiuquan Luo (Plano, Texas); Xinpeng Ma (Dallas, Texas); Zachary R. Moore (Dallas, Texas); Elizabeth I. Parkinson (Champaign, Illinois) |
ABSTRACT | The therapies described herein can be selectively lethal toward a variety of different cancer cell types and cancer conditions in a subject. The combination therapies described herein can be useful for the management, treatment, control, or adjunct treatment of diseases, where the selective lethality is beneficial in chemotherapeutic therapy, particularly where the disease is accompanied by elevated levels of NQO1. |
FILED | Tuesday, April 08, 2014 |
APPL NO | 14/783344 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/131 (20130101) A61K 31/131 (20130101) A61K 31/353 (20130101) A61K 31/353 (20130101) A61K 31/706 (20130101) Original (OR) Class A61K 31/4738 (20130101) A61K 31/4738 (20130101) A61K 31/4745 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272106 | Palczewski et al. |
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FUNDED BY |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
INVENTOR(S) | Krzysztof Palczewski (Cleveland, Ohio); Timothy Kern (Cleveland, Ohio) |
ABSTRACT | A method of treating diabetic retinopathy in a subject in need thereof includes administering to the subject a therapeutically effective amount of one or more agents that act as a trap of reactive aldehydes and/or inhibit diabetes-induced superoxide generation and capillary degeneration regulated by GPCR signaling pathways. |
FILED | Thursday, June 04, 2015 |
APPL NO | 15/316412 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/12 (20130101) A61K 31/13 (20130101) A61K 31/13 (20130101) A61K 31/48 (20130101) A61K 31/48 (20130101) A61K 31/52 (20130101) A61K 31/58 (20130101) A61K 31/69 (20130101) A61K 31/155 (20130101) A61K 31/197 (20130101) A61K 31/197 (20130101) A61K 31/352 (20130101) A61K 31/498 (20130101) A61K 31/505 (20130101) A61K 31/505 (20130101) A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 31/553 (20130101) A61K 31/4164 (20130101) A61K 31/4453 (20130101) A61K 31/4453 (20130101) A61K 31/7076 (20130101) A61K 33/24 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272110 | Zon et al. |
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FUNDED BY |
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APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Leonard I. Zon (Wellesley, Massachusetts); Trista E. North (Newton Center, Massachusetts); Wolfram Goessling (Chestnut Hill, Massachusetts) |
ABSTRACT | The present invention provides for compositions and methods for modulating hematopoetic stem cell populations by using HCS modulators, which are agents that either increase HSC numbers or decrease HSC numbers as desired by a particular indication. For example, HSC modulators found to increase HSC numbers include prostaglandin E2 (PGE2) and agents that stimulate the PGE2 pathway. Conversely, HSC modulators that prevent PGE2 synthesis decrease HSC numbers. HCS modulators may be used in vitro, in vivo, or ex vivo. |
FILED | Friday, March 15, 2013 |
APPL NO | 13/838002 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) A61K 35/14 (20130101) Original (OR) Class A61K 35/28 (20130101) A61K 35/50 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 2501/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272112 | Giannoukakis et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Nick Giannoukakis (Coraopolis, Pennsylvania); Massimo M. Trucco (Pittsburgh, Pennsylvania) |
ABSTRACT | The present invention relates to tolerogenic mammalian dendritic cells (iDCs) and methods for the production of tolerogenic DCs. In addition, the present invention provides methods for administration of tolerogenic dendritic cells as well as particles containing oligonucleotides to mammalian subjects. Enhanced tolerogenicity in a host can be useful for treating inflammatory and autoimmune related diseases, such as type 1 diabetes. |
FILED | Tuesday, June 27, 2017 |
APPL NO | 15/635007 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/15 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/064 (20130101) C12N 15/1138 (20130101) C12N 2310/11 (20130101) C12N 2501/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272119 | Tseng et al. |
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APPLICANT(S) | TissueTech, Inc. (Miami, Florida) |
ASSIGNEE(S) | TISSUETECH, INC. (Miami, Florida) |
INVENTOR(S) | Scheffer Tseng (Pinecrest, Florida); Hua He (Miami, Florida); Wei Li (Shenzhen, China PRC) |
ABSTRACT | Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases. |
FILED | Wednesday, June 28, 2017 |
APPL NO | 15/636227 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/982 (20130101) A61K 9/06 (20130101) A61K 9/08 (20130101) A61K 9/0014 (20130101) A61K 9/19 (20130101) A61K 9/0048 (20130101) A61K 9/0053 (20130101) A61K 31/738 (20130101) A61K 35/48 (20130101) A61K 35/50 (20130101) Original (OR) Class A61K 38/39 (20130101) A61K 38/39 (20130101) A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 38/4886 (20130101) A61K 38/4886 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2800/74 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/40 (20130101) A61L 15/44 (20130101) A61L 2300/64 (20130101) A61L 2300/412 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 19/00 (20130101) Peptides C07K 14/78 (20130101) C07K 14/4702 (20130101) C07K 14/4718 (20130101) C07K 14/8114 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272126 | Duncan et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
INVENTOR(S) | Bradley Duncan (Andover, Massachusetts); Xiaoning Li (Hillsboro, Oregon); Vincent M. Rotello (Amherst, Massachusetts) |
ABSTRACT | A stabilized microcapsule includes a liquid hydrophobic core including an essential oil and an aromatic monoaldehyde, and a shell encapsulating the core, the shell including a plurality of amino-functionalized inorganic nanoparticles. Also disclosed is a dispersion including a plurality of the stabilized microcapsules. The microcapsules and dispersions can be particularly useful for treating a bacterial biofilm. |
FILED | Thursday, July 21, 2016 |
APPL NO | 15/216134 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/04 (20130101) A01N 25/04 (20130101) A01N 25/28 (20130101) A01N 25/28 (20130101) A01N 27/00 (20130101) A01N 27/00 (20130101) A01N 27/00 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 37/40 (20130101) A01N 37/40 (20130101) A01N 37/40 (20130101) A01N 49/00 (20130101) A01N 49/00 (20130101) A01N 49/00 (20130101) A01N 65/00 (20130101) A01N 65/00 (20130101) A01N 65/00 (20130101) A01N 65/10 (20130101) A01N 65/10 (20130101) A01N 65/10 (20130101) A01N 65/22 (20130101) A01N 65/22 (20130101) A01N 65/22 (20130101) A01N 65/24 (20130101) A01N 65/24 (20130101) A01N 65/24 (20130101) A01N 65/28 (20130101) A01N 65/28 (20130101) A01N 65/28 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/501 (20130101) A61K 31/12 (20130101) A61K 36/534 (20130101) Original (OR) Class A61K 47/52 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/0082 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) Y02A 50/478 (20180101) Y02A 50/479 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272133 | Hawiger et al. |
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FUNDED BY |
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APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Jack J. Hawiger (Nashville, Tennessee); Ruth Ann Veach (Brentwood, Tennessee); Jozef Zienkiewicz (Nashville, Tennessee); Yan Liu (Nashville, Tennessee); Robert D. Collins (Nashville, Tennessee); Amy S. Major (Brentwood, Tennessee) |
ABSTRACT | The present invention relates to compositions and methods for treating diseases associated with dyslipidemia, including hypercholesterolemia, hypertriglyceridemia, steatohepatitis, atherosclerosis, obesity, hyperglycemia, metabolic syndrome, and related aspects of and conditions associated with metabolic syndrome. The compositions and methods disclosed herein are useful for regulating the lipid balance (lipid homeostasis) in a subject. Compositions and methods including a Nuclear Transport Modifier may be administered to a subject to modulate the transport of transcription factors, mediated by nuclear import adaptors, into the nucleus of a cell resulting in a decrease in cholesterol and triglyceride levels in the blood and liver, a decrease in atherosclerotic lesion size, a decrease in body weight and in hyperglycemia, a reduction of fatty liver inflammation, and an improvement in liver function. |
FILED | Monday, November 06, 2017 |
APPL NO | 15/804863 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/397 (20130101) A61K 38/08 (20130101) A61K 38/12 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272134 | Arts |
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FUNDED BY |
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APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
INVENTOR(S) | Eric J. Arts (Cleveland, Ohio) |
ABSTRACT | A method of reducing a latent HIV-specific memory-CD4+ T cell pool in a subject includes the steps of: preparing at least one HIV-1 protein coding sequence from a sample obtained from the subject, wherein the sample includes HIV-1 RNA; introducing the at least one HIV-1 protein coding sequence into at least one expression construct using yeast homologous recombination; transfecting a cell with the at least one expression construct, wherein the HIV-1 protein is secreted by the cell and administering a therapeutically effective amount of the secreted HIV-1 protein and a pharmaceutically acceptable carrier to the subject, wherein the secreted HIV-1 protein stimulates latent HIV-specific memory-CD4+ T cells to induce latent HIV-1 replication resulting in HIV-specific memory-CD4+ T cell death in the subject. |
FILED | Monday, May 08, 2017 |
APPL NO | 15/589283 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/162 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272136 | Thadhani et al. |
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FUNDED BY |
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APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Ravi Thadhani (Boston, Massachusetts); Thomas P. Stossel (Belmont, Massachusetts); Po-Shun Lee (Brookline, Massachusetts); Ananth Karumanchi (Chestnut Hill, Massachusetts) |
ABSTRACT | The invention is directed, in part, to the use of gelsolin to diagnose, monitor, and treat subjects with renal failure (e.g., chronic renal failure subjects on dialysis). |
FILED | Tuesday, January 17, 2017 |
APPL NO | 15/407458 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) Peptides C07K 14/4703 (20130101) C07K 14/4716 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6883 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/6893 (20130101) G01N 2800/347 (20130101) Technologies for Adaptation to Climate Change Y02A 50/463 (20180101) Y02A 50/471 (20180101) Y02A 50/475 (20180101) Y02A 50/478 (20180101) Y02A 50/481 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272137 | Olson et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | Eric Olson (Dallas, Texas); Douglas P. Millay (Frisco, Texas) |
ABSTRACT | The present disclosure describes the fusogenic activity of the Myomaker protein. This polypeptide, when expressed in non-muscle cells, is able to drive fusion of the cell with a muscle cell, but not with other non-muscle cells. The use of this protein and cell expressing it in the delivery of exogenous genetic material to muscle cells also is described. |
FILED | Friday, June 27, 2014 |
APPL NO | 14/900005 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/1719 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 14/4716 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/16 (20130101) C12N 15/02 (20130101) C12N 2740/10043 (20130101) C12N 2740/10071 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272138 | Perrin |
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FUNDED BY |
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APPLICANT(S) | TUFTS UNIVERSITY (Boston, Massachusetts) |
ASSIGNEE(S) | TUFTS UNIVERSITY (Boston, Massachusetts) |
INVENTOR(S) | Mercio A. Perrin (Boston, Massachusetts) |
ABSTRACT | The invention provides compositions and methods for treating inflammatory diseases, such as cardiac or hepatic inflammatory diseases, involving the use of parasite-derived neurotrophic factor (PDNF), or fragment of PDNF. |
FILED | Thursday, August 03, 2017 |
APPL NO | 15/668251 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) A61K 38/47 (20130101) Original (OR) Class Enzymes C12Y 302/01018 (20130101) Technologies for Adaptation to Climate Change Y02A 50/414 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272145 | Kurtis et al. |
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FUNDED BY |
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APPLICANT(S) | Rhode Island Hospital (Providence, Rhode Island); Seattle Biomedical Research Institute (Seattle, Washington) |
ASSIGNEE(S) | Rhode Island Hospital (Providence, Rhode Island); Seattle Biomedical Research Institute (Seattle, Washington) |
INVENTOR(S) | Jonathan Kurtis (Providence, Rhode Island); Christian Parcher Nixon (Little Compton, Rhode Island); Dipak Kumar Raj (Pawtucket, Rhode Island); Jennifer Frances Friedman (Providence, Rhode Island); Michal Fried (Rockville, Maryland); Patrick Emmet Duffy (Washington, District of Columbia) |
ABSTRACT | The invention provides compositions and methods for preventing or reducing the severity of malaria. |
FILED | Wednesday, October 19, 2016 |
APPL NO | 15/298021 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/015 (20130101) Original (OR) Class A61K 39/39575 (20130101) A61K 2039/54 (20130101) A61K 2039/55 (20130101) A61K 2039/505 (20130101) A61K 2039/522 (20130101) A61K 2039/575 (20130101) Peptides C07K 14/445 (20130101) C07K 16/44 (20130101) C07K 16/205 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) Technologies for Adaptation to Climate Change Y02A 50/412 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272146 | Sim et al. |
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FUNDED BY |
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APPLICANT(S) | Sanaria Inc. (Rockville, Maryland) |
ASSIGNEE(S) | Sanaria Inc. (Rockville, Maryland) |
INVENTOR(S) | B. Kim Lee Sim (Gaithersburg, Maryland); Minglin Li (Ellicott City, Maryland); Richard E. Stafford (Annandale, Virginia); Stephen L. Hoffman (Gaithersburg, Maryland) |
ABSTRACT | Disclosed are substantially purified Plasmodium sporozoites and preparations of Plasmodium sporozoites substantially separated from attendant non-sporozoite material, where the preparations of Plasmodium sporozoites have increasing levels of purity. Vaccines and pharmaceutical compositions comprising purified Plasmodium sporozoites are likewise provided. Methods of purifying preparations of Plasmodium sporozoites are also provided. |
FILED | Tuesday, March 14, 2017 |
APPL NO | 15/458792 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/4706 (20130101) A61K 39/015 (20130101) Original (OR) Class A61K 2039/522 (20130101) A61K 2039/6081 (20130101) Technologies for Adaptation to Climate Change Y02A 50/412 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
10272160 — Nanostructures comprising cobalt porphyrin-phospholipid conjugates and polyhistidine-tags
US 10272160 | Lovell et al. |
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FUNDED BY |
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APPLICANT(S) | The Research Foundation for The State University of New York (Buffalo, New York) |
ASSIGNEE(S) | The Research Foundation for The State University of New York (Amherst, New York); PATH (Seattle, Washington) |
INVENTOR(S) | Jonathan Lovell (Niagara Falls, Canada); Shuai Shao (Tonawanda, New York); Jumin Geng (Williamsville, New York); Wei-Chiao Huang (Amherst, New York); Shwu-Maan Lee (Rockville, Maryland); Charles Richter King (Washington, District of Columbia) |
ABSTRACT | The present disclosure provides nanostructures (e.g., monolayer or bilayer nanostructures) comprising porphyrins with cobalt chelated thereto such that the cobalt metal resides within monolayer or bilayer in the porphyrin macrocycle. The nanostructures can have presentation molecules with a histidine tag attached thereto, such that at least a part of the his-tag is within the monolayer or bilayer and coordinated to the cobalt metal core and the presentation molecules are exposed to the outside of the nanostructures. The nanostructures can further comprise a cargo. The nanostructures can be used to deliver the cargo to an individual. |
FILED | Monday, April 18, 2016 |
APPL NO | 15/566140 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 38/41 (20130101) A61K 38/162 (20130101) A61K 47/544 (20170801) A61K 47/6911 (20170801) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 14/795 (20130101) C07K 2319/21 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272163 | Laterza et al. |
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FUNDED BY |
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APPLICANT(S) | HAPLOMICS, INC. (Atlanta, Georgia); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America Represented by the Department of Veterans Affairs (Washington, District of Columbia); Haplomics, Inc. (Manhatten Beach, California) |
INVENTOR(S) | Vincent Laterza (Atlanta, Georgia); Tommy E. Howard (Redondo Beach, California) |
ABSTRACT | Methods of treating hemophilia A in a subject with an F8 gene mutation, wherein the F8 gene is repaired and the resultant repaired gene, upon expression, confers improved coagulation functionality to the encoded FVIII protein of the subject compared to the non-repaired F8 gene. The invention also includes methods of inducing immune tolerance to a FVIII replacement product ((r)FVIII) in a subject having a FVIII deficiency, wherein the F8 gene mutation is repaired and the repaired gene, upon expression, provides for the induction of immune tolerance to an administered replacement FVIII protein product. The invention also includes isolated nucleic acids, vectors, recombinant viruses, cells, and pharmaceutical compositions to repair the F8 gene. |
FILED | Friday, December 06, 2013 |
APPL NO | 14/649910 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/0066 (20130101) Original (OR) Class Peptides C07K 14/755 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/90 (20130101) C12N 2830/42 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272165 | Rossi et al. |
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FUNDED BY |
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APPLICANT(S) | CITY OF HOPE (Duarte, California) |
ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
INVENTOR(S) | John J. Rossi (Alta Loma, California); Maggie Bobbin (Duarte, California) |
ABSTRACT | An aptamer-mRNA conjugate is provided. The aptamer-mRNA conjugate may include an aptamer component that binds a membrane associated protein on a target cell and an mRNA component that is expressed by the target cell. |
FILED | Monday, July 11, 2016 |
APPL NO | 15/207280 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 47/549 (20170801) A61K 48/00 (20130101) A61K 49/12 (20130101) Original (OR) Class A61K 49/0054 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/115 (20130101) C12N 15/1132 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/3519 (20130101) C12N 2320/32 (20130101) Enzymes C12Y 301/21004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272409 | Hogan et al. |
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FUNDED BY |
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APPLICANT(S) | Michael E. Hogan (Tucson, Arizona); Sergy Lemeshko (Houston, Texas); Yuri Belosludtsev (The Woodlands, Texas); Thomas F. Powdrill (College Station, Texas); Rahul Mitra (Pearland, Texas); Joseph G. Utermohlen (Tucson, Arizona); Frederick H. Eggers (Oro Valley, Arizona) |
ASSIGNEE(S) | |
INVENTOR(S) | Michael E. Hogan (Tucson, Arizona); Sergy Lemeshko (Houston, Texas); Yuri Belosludtsev (The Woodlands, Texas); Thomas F. Powdrill (College Station, Texas); Rahul Mitra (Pearland, Texas); Joseph G. Utermohlen (Tucson, Arizona); Frederick H. Eggers (Oro Valley, Arizona) |
ABSTRACT | Provided herein are biomolecular hybridization devices comprising a substrate with a permanently and covalently attached surface of functional groups and an adsorbed monolayer of unmodified, single-stranded oligonucleotides all of which are 10 to about 24 bases in length as a saturated film of constrained oligonucleotides on the surface via direct non-covalent phosphate-surface adsorptive contact of substantially all phosphate groups of each oligonucleotide. The constrained oligonucleotides are effective to dissociably hybridize to a complementary single-stranded nucleic acid with asymmetric, non-helical base pairing and without oligonucleotide dissociation from the surface of the device. Also, provided are methods for hybridizing solution-state target nucleic acids to probe nucleic acids and for identifying a nucleotide sequence to which a nucleotide-binding protein binds using the biomolecular hybridization devices. |
FILED | Friday, April 04, 2008 |
APPL NO | 12/080720 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/005 (20130101) B01J 2219/00376 (20130101) B01J 2219/00497 (20130101) B01J 2219/00576 (20130101) B01J 2219/00605 (20130101) B01J 2219/00653 (20130101) B01J 2219/00659 (20130101) B01J 2219/00677 (20130101) B01J 2219/00691 (20130101) B01J 2219/00722 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273202 | Toscano et al. |
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FUNDED BY |
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APPLICANT(S) | John P. Toscano (Glen Arm, Maryland); Christopher M. Pavlos (Laurel, Maryland); Preeya Kapur Boppana (Frederick, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | John P. Toscano (Glen Arm, Maryland); Christopher M. Pavlos (Laurel, Maryland); Preeya Kapur Boppana (Frederick, Maryland) |
ABSTRACT | Described herein are nitroxyl progenitor compounds, and compositions including, and methods or generating, the compounds thereof, and methods of treating or preventing disease and disease symptoms using the compounds and compositions. |
FILED | Monday, September 22, 2014 |
APPL NO | 14/492741 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 247/16 (20130101) Original (OR) Class C07C 247/18 (20130101) C07C 291/08 (20130101) Heterocyclic Compounds C07D 207/50 (20130101) C07D 209/42 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
10273214 — Subunit selective NMDA receptor potentiators for the treatment of neurological conditions
US 10273214 | Traynelis et al. |
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FUNDED BY |
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APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Stephen F. Traynelis (Decatur, Georgia); Dennis C. Liotta (Atlanta, Georgia); Rose M. Santangelo (Decatur, Georgia); Ethel C. Garnier (Tucker, Georgia) |
ABSTRACT | Provided are compounds, pharmaceutical compositions and methods of treating or preventing disorders associated with NMDA receptor activity, including schizophrenia, Parkinson's disease, cognitive disorders, depression, neuropathic pain, stroke, traumatic brain injury, epilepsy, and related neurologic events or neurodegeneration. Compounds of the general Formulas A-J, and pharmaceutically acceptable salts, esters, prodrugs or derivatives thereof are disclosed. |
FILED | Monday, June 02, 2014 |
APPL NO | 14/292957 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 209/08 (20130101) C07D 215/22 (20130101) C07D 217/16 (20130101) Original (OR) Class C07D 239/88 (20130101) C07D 263/58 (20130101) C07D 277/34 (20130101) C07D 401/04 (20130101) C07D 401/06 (20130101) C07D 405/06 (20130101) C07D 409/04 (20130101) C07D 409/06 (20130101) C07D 413/06 (20130101) C07D 491/056 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273228 | Arnold et al. |
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FUNDED BY |
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APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); Assembly Biosciences, Inc. (Carmel, Indiana) |
INVENTOR(S) | Lee Daniel Arnold (Bloomington, Indiana); Hans Maag (Kleines Wiesental, Germany); William W. Turner, Jr. (Bloomington, Indiana) |
ABSTRACT | Novel assembly effector compounds having a therapeutic effect against hepatitis B viral (HBV) infection are disclosed. Assembly effector molecules described herein can lead to defective viral assembly and also may affect other viral activities associated with chronic HBV infection. Also disclosed is a process to synthesize disclosed compounds, method of treatment of HBV by administration of disclosed compounds, and use of these compounds in the manufacture of medicaments against HBV. |
FILED | Friday, April 15, 2016 |
APPL NO | 15/566633 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/506 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) Heterocyclic Compounds C07D 213/74 (20130101) C07D 239/42 (20130101) C07D 239/47 (20130101) C07D 239/48 (20130101) C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/04 (20130101) C07D 403/12 (20130101) C07D 403/14 (20130101) Original (OR) Class C07D 409/12 (20130101) C07D 413/04 (20130101) C07D 417/04 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273243 | Petrukhin et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Konstantin Petrukhin (New Windsor, New York); Christopher Cioffi (Troy, New York); Graham Johnson (Sanbornton, New Hampshire); Nicoleta Dobri (New York, New York); Emily Freeman (Voorheesville, New York); Ping Chen (Slingerlands, New York); Michael Conlon (Schenectady, New York); Lei Zhu (Glenmont, New York) |
ABSTRACT | The present invention provides a compound having the structure: (structurally represented) wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl; R6 is H, OH, or halogen; B is a substituted or unsubstituted heterobicycle, pyridazine, pyrazole, pyrazine, thiadiazole, or triazole, wherein the heterobicycle is other than chloro substituted indole; and the pyrazole, when substituted, is substituted with other than trifluoromethyl, or a pharmaceutically acceptable salt thereof. |
FILED | Thursday, March 13, 2014 |
APPL NO | 14/775532 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 401/06 (20130101) C07D 405/14 (20130101) C07D 409/06 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 491/052 (20130101) C07D 495/04 (20130101) C07D 498/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273260 | Janetka et al. |
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FUNDED BY |
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APPLICANT(S) | Washington University (St. Louis, Missouri) |
ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
INVENTOR(S) | James W. Janetka (St. Louis, Missouri); Zhenfu Han (St. Louis, Missouri); Scott Hultgren (St. Louis, Missouri); Jerome S. Pinkner (St. Louis, Missouri); Corinne Cusumano (St. Louis, Missouri) |
ABSTRACT | The present invention encompasses compounds and methods for treating urinary tract infections. |
FILED | Thursday, December 08, 2016 |
APPL NO | 15/373260 |
ART UNIT | 1673 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/10 (20130101) A01N 43/16 (20130101) A01N 43/38 (20130101) A01N 43/42 (20130101) A01N 43/52 (20130101) A01N 43/54 (20130101) A01N 43/76 (20130101) A01N 43/78 (20130101) A01N 47/36 (20130101) A01N 55/08 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/706 (20130101) A61K 31/7034 (20130101) A61K 31/7042 (20130101) A61K 31/7048 (20130101) A61K 31/7056 (20130101) Heterocyclic Compounds C07D 309/10 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/20 (20130101) Original (OR) Class C07H 15/22 (20130101) C07H 15/26 (20130101) C07H 15/203 (20130101) C07H 15/207 (20130101) C07H 19/056 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273271 | Joung et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Jeffry D. Sander (Ankeny, Iowa) |
ABSTRACT | The disclosure describes methods that include providing a first nucleic acid having a sequence encoding a first set comprising one or more transcription activator-like effector (TALE) repeat domains and/or one or more portions of one or more TALE repeat domains; contacting the first nucleic acid with a first enzyme, wherein the first enzyme creates a first ligatable end; providing a second nucleic acid having a sequence encoding a second set comprising one or more TALE repeat domains and/or one or more portions of one or more TALE repeat domains; contacting the second nucleic acid with a second enzyme, wherein the second enzyme creates a second ligatable end, and wherein the first and second ligatable ends are compatible; and ligating the first and second nucleic acids through the first and second ligatable ends to produce a first ligated nucleic acid, wherein the first ligated nucleic acid is linked to a solid support, and wherein the first ligated nucleic acid encodes a polypeptide comprising said first and second sets. |
FILED | Tuesday, May 17, 2016 |
APPL NO | 15/156574 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Peptides C07K 14/195 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/24 (20130101) C07K 2319/41 (20130101) C07K 2319/43 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/66 (20130101) C12N 15/1093 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) C12P 21/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 2521/501 (20130101) C12Q 2563/149 (20130101) Enzymes C12Y 301/00 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/08 (20130101) C40B 50/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273274 | Greene et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Lloyd A. Greene (Larchmont, New York); James Angelastro (Davis, California) |
ABSTRACT | The present invention relates to methods for treating and/or preventing tumors and/or promoting apoptosis in a neoplastic cell comprising contacting the neoplastic cell with an cell-penetrating dominant-negative ATF5 (“CP-d/n-ATF5”), wherein the CP-d/n-ATF5 is capable of inhibiting ATF5 function and/or activity. |
FILED | Friday, December 22, 2017 |
APPL NO | 15/853087 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) A61K 38/00 (20130101) A61K 38/1709 (20130101) Peptides C07K 14/4705 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273279 | Mosnier et al. |
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FUNDED BY |
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APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Laurent O. Mosnier (San Diego, California); John H. Griffin (Del Mar, California) |
ABSTRACT | The present invention provides novel PAR1 derived cytoprotective oligopeptides or polypeptides which typically contain at least the first 4 N-terminal residues that are substantially identical to the corresponding N-terminal residues of Met1-Arg46 deleted human PAR1 sequence. These cytoprotective oligopeptides or polypeptides are capable of activating PAR1 and promoting PAR1 cytoprotective signaling activities. The invention also provides engineered cells or transgenic non-human animals which harbor in their genome an altered PAR1 gene that is resistant to cleavage at Arg41 and/or Arg46 residues. Additionally provided in the invention are methods of screening candidate compounds to identity additional cytoprotective compounds or cytoprotective proteases. The invention further provides therapeutic use or methods of employing a PAR1 derived cytoprotective oligopeptide or polypeptide to treat conditions associated with tissue injuries or undesired apoptosis. |
FILED | Monday, March 27, 2017 |
APPL NO | 15/470117 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/177 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273288 | Sullivan et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Institute for Research in Biomedicine (Bellinzona, Switzerland); The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia); Humabs BioMed SA (Bellinzona, Switzerland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Institute for Research in Biomedicine (Bellinzona, Switzerland); The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia); Humabs Biomed SA (Bellinzona, Switzerland) |
INVENTOR(S) | Nancy Sullivan (Kensington, Maryland); Sabue Mulangu (Bethesda, Maryland); Davide Corti (Bellinzona, Switzerland); Antonio Lanzavecchia (Bellinzona, Switzerland); Barney Graham (Rockville, Maryland); Jean-Jacques Muyembe-Tamfun (Kinshasa, Congo); John Trefry (Frederick, Maryland); Julie Ledgerwood (Bethesda, Maryland); Daphne Stanley (Bethesda, Maryland) |
ABSTRACT | Neutralizing antibodies and antigen binding fragments that specifically bind to Ebola virus glycoprotein are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting Ebola virus using the antibodies and antigen binding fragments are disclosed. The antibodies, antigen binding fragments, nucleic acids, and vectors, can be used, for example, to prevent and/or treat Ebola virus infection in a subject. |
FILED | Wednesday, November 14, 2018 |
APPL NO | 16/190676 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/52 (20130101) C07K 2317/56 (20130101) C07K 2317/72 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) C07K 2317/732 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/08 (20130101) G01N 2800/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273290 | Walensky et al. |
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FUNDED BY |
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APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
INVENTOR(S) | Loren D. Walensky (Chestnut Hill, Massachusetts); Gregory Bird (Pelham, New Hampshire) |
ABSTRACT | The invention provides structurally constrained viral peptides for use as therapeutic and vaccination agents, and for the production of antibodies for use in a number of applications including as therapeutic agents. The invention further provides methods and kits for use of the structurally constrained peptides and antibodies of the instant invention. The invention is based, at least in part, on the result provided herein demonstrating the viral hydrocarbon stapled helical peptides display excellent proteolytic, acid, and thermal stability, restore the native helical structure of the peptide, are highly effective in interfering with the viral fusogenic process, and possess superior pharmacokinetic properties compared to the corresponding unmodified peptides. |
FILED | Thursday, September 21, 2017 |
APPL NO | 15/711058 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Peptides C07K 16/1045 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16034 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273291 | Mascola et al. |
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FUNDED BY |
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APPLICANT(S) | John R. Mascola (Bethesda, Maryland); Gary Nabel (Bethesda, Maryland); Barton F. Haynes (Durham, North Carolina); Xueling Wu (Bethesda, Maryland); Thomas B. Kepler (Boston, Massachusetts); Peter Kwong (Bethesda, Maryland) |
ASSIGNEE(S) | Duke University (Durham, North Carolina); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH (Washington, District of Columbia) |
INVENTOR(S) | John R. Mascola (Bethesda, Maryland); Gary Nabel (Bethesda, Maryland); Barton F. Haynes (Durham, North Carolina); Xueling Wu (Bethesda, Maryland); Thomas B. Kepler (Boston, Massachusetts); Peter Kwong (Bethesda, Maryland) |
ABSTRACT | Antibody VRC01 represents a human immunoglobulin that neutralizes—˜90% of diverse HIV-1 isolates. To understand how such broadly neutralizing HIV-1 antibodies develop and recognize the viral envelope, we used X-ray crystallography and 454 pyrosequencing to characterize additional antibodies from HIV-1-infected individuals. Crystal structures revealed a convergent mode of binding of different antibodies to the same CD4-binding-site epitope. Antibody recognition was achieved through the evolution of complementary contact domains that were generated in diverse ways. Phylogenetic analysis of expressed heavy and light chains determined by deep sequencing revealed a common pathway of antibody heavy chain maturation confined to IGHV1-2*02 lineage that could pair with different light chains. The maturation pathway inferred by antibodyomics reveals that diverse antibodies evolve to a highly affinity-matured state to recognize an invariant viral structure, providing insight into the development and evolution of broadly neutralizing HIV-1 immunity. |
FILED | Friday, March 23, 2012 |
APPL NO | 14/116710 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273294 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
INVENTOR(S) | Wei Li (Altadena, California); David Woodley (Altadena, California); Mei Chen (Altadena, California); Divya Sahu (San Diego, California); Hangming Dong (Guangzhou, China PRC); Mengchen Zou (Guangzhou, China PRC) |
ABSTRACT | Described herein are compositions that include monoclonal antibodies that specifically bind Hsp90α and methods of using the same to treat HIF-1α-overexpressing cancer. In some embodiments, the cancers are breast cancer or lung cancer. The monoclonal antibodies bind the epitope TKPIWTRNP (SEQ ID NO: 1) in Hsp90α or VKHFSVEGQ (SEQ ID NO: 2) in Hsp90α. |
FILED | Wednesday, November 04, 2015 |
APPL NO | 14/932908 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/2857 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/10 (20130101) C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2310/531 (20130101) C12N 2330/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273299 | Frankel et al. |
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FUNDED BY |
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APPLICANT(S) | SCOTT and WHITE HEALTHCARE (Temple, Texas) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Arthur E. Frankel (Temple, Texas); Yunpeng Su (Katy, Texas); Brad St. Croix (Frederick, Maryland); Stephen H. Leppla (Bethesda, Maryland) |
ABSTRACT | The present invention is directed to particular antibodies and fragments thereof that find use in the detection, prevention and treatment of diseases and disorders associated with abnormal angiogenesis. In particular, these antibodies detect tumor endothelial marker 8 (TEM8) in its native and cell-surface expressed form. Also disclosed are improved methods for producing monoclonal antibodies, as well as pharmaceutical compositions and kits. |
FILED | Monday, April 04, 2016 |
APPL NO | 15/090058 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 47/6809 (20170801) A61K 47/6811 (20170801) A61K 47/6849 (20170801) A61K 47/6851 (20170801) Peptides C07K 16/28 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/35 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273311 | Desir et al. |
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FUNDED BY |
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APPLICANT(S) | Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
INVENTOR(S) | Gary Desir (Woodbridge, Connecticut); Abigail Hunt (Alameda, California); Jessica O-Rear (Redwood City, California); Peter Flynn (San Francisco, California) |
ABSTRACT | The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules act as therapeutics. |
FILED | Friday, June 26, 2015 |
APPL NO | 15/321015 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/40 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2317/51 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/515 (20130101) C07K 2317/565 (20130101) Enzymes C12Y 106/03 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 2333/90209 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273407 | Collins et al. |
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FUNDED BY |
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APPLICANT(S) | INTELLIGENT MATERIAL SOLUTIONS, INC. (Princeton, New Jersey); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | INTELLIGENT MATERIAL SOLUTIONS, INC. (Princeton, New Jersey); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
INVENTOR(S) | Joshua E. Collins (Philadelphia, Pennsylvania); Howard Y. Bell (Princeton, New Jersey); Xingchen Ye (Philadelphia, Pennsylvania); Christopher Bruce Murray (Montgomery County, Pennsylvania) |
ABSTRACT | Monodisperse particles having: a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology are disclosed. Due to their uniform size and shape, the monodisperse particles self assemble into superlattices. The particles may be luminescent particles such as down-converting phosphor particles and up-converting phosphors. The monodisperse particles of the invention have a rare earth-containing lattice which in one embodiment may be an yttrium-containing lattice or in another may be a lanthanide-containing lattice. The monodisperse particles may have different optical properties based on their composition, their size, and/or their morphology (or shape). Also disclosed is a combination of at least two types of monodisperse particles, where each type is a plurality of monodisperse particles having a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology; and where the types of monodisperse particles differ from one another by composition, by size, or by morphology. In a preferred embodiment, the types of monodisperse particles have the same composition but different morphologies. Methods of making and methods of using the monodisperse particles are disclosed. |
FILED | Thursday, August 30, 2018 |
APPL NO | 16/117453 |
ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 15/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/0031 (20130101) C01F 17/0043 (20130101) C01F 17/0062 (20130101) C01F 17/0087 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/54 (20130101) C01P 2002/72 (20130101) C01P 2002/84 (20130101) C01P 2004/04 (20130101) C01P 2004/10 (20130101) C01P 2004/11 (20130101) C01P 2004/16 (20130101) C01P 2004/20 (20130101) C01P 2004/32 (20130101) C01P 2004/40 (20130101) C01P 2004/42 (20130101) C01P 2004/52 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7773 (20130101) C09K 11/7791 (20130101) Original (OR) Class Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/08 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2933 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273451 | Hoke et al. |
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FUNDED BY |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Ahmet Hoke (Towson, Maryland); Weiran Chen (Columbia, Maryland) |
ABSTRACT | The instant invention provides methods for immortalizing cells. The invention further provides immortalized cell lines, e.g., neuronal cell lines, and methods of using these cell lines in screening assays. |
FILED | Friday, January 16, 2015 |
APPL NO | 14/598955 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 9/1276 (20130101) C12N 2510/04 (20130101) C12N 2799/027 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) G01N 2500/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
10273452 — Specification of functional cranial placode derivatives from human pluripotent stem cells
US 10273452 | Chambers et al. |
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FUNDED BY |
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APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
INVENTOR(S) | Stuart Chambers (New York, New York); Lorenz Studer (New York, New York); Zehra Dincer (New York, New York); Bastian Zimmer (New York, New York) |
ABSTRACT | Cranial placodes are embryonic structures essential for sensory and endocrine organ development. The efficient derivation of cranial placodes from human pluripotent stem cells is disclosed where the timed removal of the BMP inhibitor Noggin, a component of the dual-SMAD inhibition strategy of neural induction, triggers placode induction at the expense of CNS fates. Further fate specification at the pre-placode stage enables the selective generation of placode-derived trigeminal ganglia capable of in vivo engraftment, mature lens fibers and anterior pituitary hormone-producing cells that upon transplantation produce hormones including, but not limited to, human growth hormone and adrenocortiocotropic hormone in vivo. Alternatively, anterior pituitary hormone-producing cells are generated in cell culture systems in vitro. |
FILED | Thursday, May 19, 2016 |
APPL NO | 15/159351 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) Heterocyclic Compounds C07D 211/00 (20130101) C07D 243/36 (20130101) C07D 307/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 2501/13 (20130101) C12N 2501/41 (20130101) C12N 2501/119 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2501/734 (20130101) C12N 2501/998 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273458 | Ko et al. |
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FUNDED BY |
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APPLICANT(S) | Minoru S. H. Ko (Cockeysville, Maryland); Shigeru B. H. Ko (Inuyama, Japan) |
ASSIGNEE(S) | Elixirgen, LLC (Baltimore, Maryland) |
INVENTOR(S) | Minoru S. H. Ko (Cockeysville, Maryland); Shigeru B. H. Ko (Inuyama, Japan) |
ABSTRACT | ZSCAN4, a gene expressed in ES cells and 2-cell stage embryos, has been previously shown to regulate telomere elongation and genome stability in mouse ES cells. It is disclosed herein that in the adult human pancreas, a small number of ZSCAN4-positive cells are present among cells located in the islets of Langerhans, acini, and ducts. These data disclosed herein indicates that expression of ZSCAN4 is a marker for rare stem/progenitor cells in adult human pancreas. Thus, provided herein is a method of isolating pancreatic stem cells or progenitor cell from a sample by detecting expression of ZSCAN4. Also provided is a method of treating diabetes by isolating ZSCAN4+ pancreatic stem cells or progenitor cells, expanding the cells in vitro and transplanted the expanded cells into the subject. The expanded ZSCAN4+ cells can optionally be differentiated into pancreatic β cells before transplanting the cells into the subject. Further provided is an in vivo method of expanding a population of pancreatic stem cells or progenitor cells in a subject by delivering a ZSCAN4 protein, a ZSCAN4 nucleic acid sequence, or an agent that increases expression of ZSCAN4 to the pancreas of the subject. |
FILED | Wednesday, January 25, 2012 |
APPL NO | 13/981891 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/39 (20130101) A61K 38/1709 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0678 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/507 (20130101) G01N 33/5073 (20130101) G01N 33/6893 (20130101) G01N 33/56966 (20130101) G01N 2800/042 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273468 | Tolia et al. |
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FUNDED BY |
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APPLICANT(S) | Niraj Tolia (St. Louis, Missouri); Gautam Dantas (St. Louis, Missouri); Timothy Wencewicz (St. Louis, Missouri); Jooyoung Park (St. Louis, Missouri); Andrew Gasparrini (St. Louis, Missouri); Kevin Forsberg (St. Louis, Missouri); Joseph Vogel (St. Louis, Missouri); Margaret Ruth Reck (St. Louis, Missouri); Chanez Tiffany Symister (St. Louis, Missouri); Jana L. Markley (St. Louis, Missouri) |
ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Niraj Tolia (St. Louis, Missouri); Gautam Dantas (St. Louis, Missouri); Timothy Wencewicz (St. Louis, Missouri); Jooyoung Park (St. Louis, Missouri); Andrew Gasparrini (St. Louis, Missouri); Kevin Forsberg (St. Louis, Missouri); Joseph Vogel (St. Louis, Missouri); Margaret Ruth Reck (St. Louis, Missouri); Chanez Tiffany Symister (St. Louis, Missouri); Jana L. Markley (St. Louis, Missouri) |
ABSTRACT | The present disclosure provides compositions and methods for treating bacterial infections in a subject. The methods comprise administering a compound that binds a FAD-dependent flavoenzyme and a tetracycline, analog, derivative, or pharmaceutically acceptable salt thereof. |
FILED | Monday, June 26, 2017 |
APPL NO | 15/633254 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/65 (20130101) A61K 38/005 (20130101) A61K 39/40 (20130101) A61K 47/00 (20130101) A61K 47/6809 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/00 (20130101) C12N 9/99 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) Technologies for Adaptation to Climate Change Y02A 50/478 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273474 | Miller et al. |
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FUNDED BY |
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APPLICANT(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri); ISIS PHARMACEUTICALS, INC. (Carlsbad, California) |
ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri); ISIS PHARMACEUTICALS, INC. (Carlsbad, California) |
INVENTOR(S) | Timothy M. Miller (St. Louis, Missouri); Sarah Devos (St. Louis, Missouri); C. Frank Bennett (Carlsbad, California); Frank Rigo (Carlsbad, California) |
ABSTRACT | Disclosed herein are methods for reducing expression of Tau mRNA and protein in an animal with Tau antisense compounds. Also disclosed are methods for modulating splicing of Tau mRNA in an animal with Tau antisense compounds. Such methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof. Examples of neurodegenerative diseases that can be treated, prevented, and ameliorated with the administration Tau antisense oligonucleotides include Alzheimer's Disease, Fronto-temporal Dementia (FTD), FTDP-17, Progressive Supranuclear Palsy, Chronic Traumatic Encephalopathy, Epilepsy, and Dravet's Syndrome. |
FILED | Thursday, March 14, 2013 |
APPL NO | 14/387853 |
ART UNIT | 1674 — Organic Chemistry |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/341 (20130101) C12N 2310/346 (20130101) C12N 2310/3341 (20130101) C12N 2310/3525 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273476 | Hong et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
INVENTOR(S) | Liu Hong (Iowa City, Iowa); Brad Amendt (Iowa City, Iowa); Thad Sharp (Iowa City, Iowa); Aliasger Salem (Iowa City, Iowa) |
ABSTRACT | In certain embodiments, the present invention provides the use of microRNA (miR)-200a and/or miR-200c to inhibit ossification and bone formation. In certain embodiments, the present invention provides the use of miR-200a inhibitor to stimulate bone regeneration. |
FILED | Monday, May 01, 2017 |
APPL NO | 15/583564 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1641 (20130101) A61K 9/1647 (20130101) A61K 9/5153 (20130101) A61K 31/713 (20130101) A61K 48/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 2300/258 (20130101) A61L 2300/412 (20130101) A61L 2430/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) C12N 2330/51 (20130101) C12N 2740/15043 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273483 | McNally et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
ASSIGNEE(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
INVENTOR(S) | Elizabeth McNally (Oak Park, Illinois); Eugene Wyatt (Chicago, Illinois) |
ABSTRACT | The invention is directed to one or more antisense polynucleotides and their use in pharmaceutical compositions in a strategy to induce exon skipping in the γ-sarcoglycan gene in patients suffering from Limb-Girdle Muscular Dystrophy-2C (LGM-D2C) or in patients at risk of such a disease. The invention also provides methods of preventing or treating muscular dystrophy, e.g., LGMD2C, by exon skipping in the gamma sarcoglycan gene using antisense polynucleotides. Accordingly, in some aspects the invention provides an isolated antisense oligonucleotide, wherein the oligonucleotide specifically hybridizes to an exon target region of a γ-sarcoglycan RNA. In another aspect, the invention provides a method of inducing exon-skipping of a gamma sarcoglycan RNA, comprising delivering an antisense oligonucleotide or a composition to a cell. |
FILED | Thursday, April 07, 2016 |
APPL NO | 15/564681 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/31 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/346 (20130101) C12N 2310/351 (20130101) C12N 2310/3181 (20130101) C12N 2310/3233 (20130101) C12N 2310/3513 (20130101) C12N 2310/3521 (20130101) C12N 2310/3521 (20130101) C12N 2320/33 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273501 | Church et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | George M. Church (Brookline, Massachusetts); Prashant G. Mali (Somerville, Massachusetts); Luhan Yang (Somerville, Massachusetts) |
ABSTRACT | A method of altering a eukaryotic cell is provided including transfecting the eukaryotic cell with a nucleic acid encoding RNA complementary to genomic DNA of the eukaryotic cell, transfecting the eukaryotic cell with a nucleic acid encoding an enzyme that interacts with the RNA and cleaves the genomic DNA in a site specific manner, wherein the cell expresses the RNA and the enzyme, the RNA binds to complementary genomic DNA and the enzyme cleaves the genomic DNA in a site specific manner. |
FILED | Thursday, July 02, 2015 |
APPL NO | 14/790147 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/01 (20130101) C12N 15/10 (20130101) C12N 15/63 (20130101) C12N 15/81 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 15/87 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/907 (20130101) C12N 15/1024 (20130101) C12N 15/8201 (20130101) C12N 2800/80 (20130101) C12N 2810/55 (20130101) Enzymes C12Y 301/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273503 | Sauvageau et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSTÉ DE MONTRÉAL (Montréal, Québec, Canada); BRITISH COLUMBIA CANCER AGENCY BRANCH (Vancouver, British Columbia, Canada); FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
ASSIGNEE(S) | UNIVERSITE DE MONTREAL (Montreal, Quebec, Canada); BRITISH COLUMBIA CANCER AGENCY BRANCH (Vancouver, British Columbia, Canada); FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
INVENTOR(S) | Guy Sauvageau (Montréal, Canada); Keith Richard Humphries (Vancouver, Canada); Hans-Peter Kiem (Seattle, Washington); Iman Fares (Montréal, Canada); Jalila Chagraoui (Montréal, Canada) |
ABSTRACT | Methods and compositions for enhancing viral gene transfer, such as lentiviral gene transfer, and improving the efficacy of gene delivery to cells such as primitive hematopoietic cells, are described. These methods and compositions are based on the use of pyrimido[4,5-b]indole derivatives. Cell-based compositions and methods useful for therapeutic indications amenable to treatment with gene therapies, including hematopoietic stem cell therapies, are also described. |
FILED | Thursday, September 17, 2015 |
APPL NO | 15/512361 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 48/00 (20130101) Heterocyclic Compounds C07D 487/04 (20130101) C07D 519/00 (20130101) Peptides C07K 5/0806 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 15/87 (20130101) C12N 2501/999 (20130101) C12N 2510/00 (20130101) C12N 2740/15043 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273511 | Lemke et al. |
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FUNDED BY |
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APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Rachelle A. S. Lemke (Madison, Wisconsin); Timothy James Donohue (Middleton, Wisconsin); Joshua J. Coon (Middleton, Wisconsin); Amelia C. Peterson (Bremen, Germany); Michael S. Westphall (Fitchburg, Wisconsin) |
ABSTRACT | Enzymes for producing non-straight-chain fatty acids, microorganisms comprising the enzymes, and in vivo and in vitro uses of the enzymes. Provided are enzymes capable of producing various non-straight-chain fatty acids, including branched-chain fatty acids, cyclic fatty acids, and furan-containing fatty acids. The enzymes include RSP2144, RSP1091, and RSP1090 from Rhodobacter sphaeroides and homologs thereof. The enzymes can be purified to produce non-straight-chain fatty acids in vitro or expressed in microorganisms to produce non-straight-chain fatty acids in vivo. The microorganisms can be fine-tuned to produce a specific type of non-straight-chain fatty acid by expressing, overexpressing, or deleting the enzymes in various combinations. |
FILED | Tuesday, June 30, 2015 |
APPL NO | 14/755213 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1007 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class C12P 17/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273517 | DeAngelis et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
INVENTOR(S) | Paul L. DeAngelis (Edmond, Oklahoma); Nigel J. Otto (Santa Fe, New Mexico) |
ABSTRACT | Testosteronan, a heparosan analog having the structure [-4-D-GlcUA-α1,4-D-GlcNAc-α1-]n, is produced by testosteronan synthase, a single protein that is a dual-action catalyst that utilizes UDP-GlcUA and UDP-GlcNAc to synthesize a polysaccharide having the structure [-4-D-GlcUA-α1,4-D-GlcNAc-α1-]n. |
FILED | Monday, May 15, 2017 |
APPL NO | 15/594860 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 37/0063 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/1051 (20130101) C12N 9/1241 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101) C12P 19/26 (20130101) Original (OR) Class Enzymes C12Y 101/01022 (20130101) C12Y 207/07009 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273527 | Gu et al. |
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FUNDED BY |
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APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
INVENTOR(S) | Li-Qun Gu (Columbia, Missouri); Yong Wang (Columbia, Missouri); Kai Tian (Columbia, Missouri) |
ABSTRACT | The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3′ terminus, 5′ terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample. |
FILED | Wednesday, July 13, 2016 |
APPL NO | 15/209443 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6825 (20130101) C12Q 1/6886 (20130101) C12Q 2523/307 (20130101) C12Q 2525/161 (20130101) C12Q 2525/207 (20130101) C12Q 2565/631 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273529 | Kingston et al. |
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FUNDED BY |
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APPLICANT(S) | Robert Kingston (Arlington, Massachusetts); Matthew Simon (New Haven, Connecticut); Jason Allen West (Somerville, Massachusetts) |
ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
INVENTOR(S) | Robert Kingston (Arlington, Massachusetts); Matthew Simon (New Haven, Connecticut); Jason Allen West (Somerville, Massachusetts) |
ABSTRACT | Methods and assays are provided for isolating factors including polypeptides, ribonucleic acids (RNAs) and polypeptide complexes that are associated with a target nucleic acid sequence. The target nucleic acid sequence may be comprised within chromatin. The methods are suitable for identification and characterisation of factors including non-coding RNAs (ncRNAs) that associate with specified genomic loci. |
FILED | Monday, August 20, 2012 |
APPL NO | 14/239369 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6811 (20130101) C12Q 1/6813 (20130101) C12Q 1/6834 (20130101) Original (OR) Class C12Q 1/6834 (20130101) C12Q 1/6876 (20130101) C12Q 2522/101 (20130101) C12Q 2523/101 (20130101) C12Q 2523/101 (20130101) C12Q 2523/101 (20130101) C12Q 2523/101 (20130101) C12Q 2523/303 (20130101) C12Q 2525/207 (20130101) C12Q 2563/131 (20130101) C12Q 2563/131 (20130101) C12Q 2563/149 (20130101) C12Q 2565/133 (20130101) C12Q 2565/133 (20130101) C12Q 2565/133 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273546 | Abate-Shen et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Corinne Abate-Shen (New York, New York); Andrea Califano (New York, New York); Michael Shen (New York, New York) |
ABSTRACT | Methods, pharmaceutical formulations and medicaments for treating prostate cancer or preventing the progression of a nonaggressive form of prostate cancer to an aggressive form, in a mammal, include a therapeutically effective amount of one or more active agents that reduce the expression or biological activity of both Forkhead box protein M1 (FOXM1) and Centromere protein F (CENPF) or biologically active fragments thereof or biologically active fragments thereof selected from the group consisting of an isolated shRNA, siRNA, antisense RNA, antisense DNA, Chimeric Antisense DNA/RNA, microRNA, and ribozymes that are sufficiently complementary to either a gene or an mRNA encoding either FOXM1 or CENPF proteins. A method is also presented for discovering synergistic master regulators of other phenotype transitions, wherein the master regulators are conserved among different species. |
FILED | Thursday, February 19, 2015 |
APPL NO | 15/119608 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57434 (20130101) G01N 2333/47 (20130101) Electric Digital Data Processing G06F 19/18 (20130101) G06F 19/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273548 | Pomerantsev et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The Unites States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Andrei P. Pomerantsev (Bethesda, Maryland); Stephen H. Leppla (Bethesda, Maryland) |
ABSTRACT | The invention relates to a Bacillus anthracis (B. anthracis) in which more than one secreted protease is inactivated by genetic modification. Such a protease-deficient B. anthracis has an improved ability to produce recombinant secreted proteins compared to other bacteria, particularly other Bacillus. Improvements include production of intact (i.e., mature full-length) proteins, often at high yield. The disclosure provides a B. anthracis that comprises a genetic modification that inactivates a protease of the M4 family of metalloproteases and a genetic modification that inactivates a protease of the M6 family of metalloproteases. Also provided is a modified B. anthracis comprising such genetic modification transformed with a recombinant molecule encoding a product, as well as methods to prepare and use such B. anthracis. |
FILED | Wednesday, December 14, 2016 |
APPL NO | 15/379002 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 2035/11 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/54 (20130101) C12N 15/75 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/07 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273549 | Helgason et al. |
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FUNDED BY |
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APPLICANT(S) | VitroLabs Inc (London, United Kingdom); King's College London (London, United Kingdom) |
ASSIGNEE(S) | VITROLABS INC. (London, United Kingdom); KING'S COLLEGE LONDON (London, United Kingdom) |
INVENTOR(S) | Ingvar Helgason (London, United Kingdom); Dusko Ilic (London, United Kingdom) |
ABSTRACT | Disclosed herein are synthetic leathers, artificial epidermal layers, artificial dermal layers, layered structures, products produced therefrom and methods of producing the same. |
FILED | Thursday, April 20, 2017 |
APPL NO | 15/493083 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0625 (20130101) C12N 5/0629 (20130101) C12N 5/0698 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2502/13 (20130101) C12N 2502/091 (20130101) C12N 2502/094 (20130101) C12N 2506/45 (20130101) C12N 2533/30 (20130101) C12N 2533/54 (20130101) Chemical Treatment of Hides, Skins or Leather, e.g Tanning, Impregnating, Finishing; Apparatus Therefor; Compositions for Tanning C14C 3/02 (20130101) Original (OR) Class C14C 13/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274478 | Balan et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Adrian Balan (Paris, France); Marija Drndic (Philadelphia, Pennsylvania) |
ABSTRACT | Provided are suspended solid-state membranes on glass chips with improved capacitance. The membranes include a first cavity formed in the thickness of the glass membrane, the first cavity having a width that increases along the direction extending from the first surface of the membrane to the second surface of the membrane, a first membrane surmounting at least a portion of the first surface of the glass membrane, the first membrane having a pore formed therethrough, and the pore of the first membrane being in fluid communication with the first cavity of the glass membrane. Also provided are related methods of fabricating the disclosed chips and of using the disclosed chips for macromolecular analysis. |
FILED | Friday, March 03, 2017 |
APPL NO | 15/448776 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 15/00 (20130101) C03C 2218/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274484 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | Mediomics LLC (St. Louis, Missouri) |
ASSIGNEE(S) | Mediomics LLC (St. Louis, Missouri) |
INVENTOR(S) | Yie-Hwa Chang (St. Louis, Missouri); Ling Tian (St. Louis, Missouri); Sally Tricomi (St. Louis, Missouri) |
ABSTRACT | The invention generally provides molecular biosensors with modular epitope binding constructs. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules. |
FILED | Friday, September 11, 2015 |
APPL NO | 14/851788 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274486 | Fan et al. |
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FUNDED BY |
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APPLICANT(S) | Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Rong Fan (Cheshire, Connecticut); Yao Lu (New Haven, Connecticut); Jonathan Chen (San Jose, California) |
ABSTRACT | The present invention relates to a system, device, and method for the high throughput multiplexed detection of a wide number of compounds. The invention comprises of a microwell array coupled to a capture agent array to form a plurality of interfaces between a microwell and a set of immobilized capture agents. The set of capture agents comprises a plurality of distinguishable features, with each feature corresponding to the detection of a particular compound of interest. In certain embodiments, each microwell is configured to contain a single cell. The invention is therefore capable of performing a high throughput analysis of single cell profiles, including profiles of secreted compounds. |
FILED | Tuesday, October 11, 2016 |
APPL NO | 15/290874 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54306 (20130101) G01N 33/54366 (20130101) Original (OR) Class G01N 33/54386 (20130101) G01N 2570/00 (20130101) G01N 2800/7028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274502 | Bobadilla et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Maria Bobadilla (Rosenau, France); Laura Badi (Basel, Switzerland); Guillemette Duchateau-Nguyen (Riedisheim, France); Laurent Essioux (Attenschwiller, France); Hanno Langen (Loerrach, Germany); Maria Chiara Magnone (Basel, Switzerland); Thomas Schindler (Loerrach, Germany); Martina Thier (Basel, Switzerland); Ivan Formentini (Basel, Switzerland); Gonzalo Christian Duran Pacheco (Riehen, Switzerland); Corinne Solier (Sierentz, France); Matthias Kretzler (Ann Arbor, Michigan); Viji Nair (Ann Arbor, Michigan); Ju Wenju (Ann Arbor, Michigan) |
ABSTRACT | Subject of the present invention are biomarkers and methods for the identification of an increased risk of the progression of chronic kidney disease (CKD), or for monitoring chronic kidney disease therapy, comprising the detecting the level of one or more of NTpro BNP, EGF, Apo H, GDF-15, and albumin-to-creatinine ratio. |
FILED | Friday, October 31, 2014 |
APPL NO | 15/034338 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2333/47 (20130101) G01N 2333/58 (20130101) G01N 2333/485 (20130101) G01N 2333/495 (20130101) G01N 2800/52 (20130101) G01N 2800/347 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274559 | Avdievich et al. |
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FUNDED BY |
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APPLICANT(S) | Transarray LLC (Lexington, Massachusetts) |
ASSIGNEE(S) | Transarray LLC (Lexington, Massachusetts) |
INVENTOR(S) | Nikolai I. Avdievich (Bronx, New York); Hoby P. Hetherington (Woodbridge, Connecticut); Jullie W. Pan (Woodbridge, Connecticut) |
ABSTRACT | There is provided a novel method and circuit of compensating for cross-talk between pairs of adjacent array elements of a transceiver phased array and double-tuned transceiver arrays for a magnetic resonance system using a resonant inductive decoupling circuit. The geometry and size of the resonant inductive decoupling circuit allows for the decoupling circuit to compensate for the cross-talk between array elements, including the reactive and resistive components of the mutual impedance while being sufficiently small to not distort a RF magnetic field of the array elements produced within a sample. |
FILED | Monday, February 05, 2018 |
APPL NO | 15/888735 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/365 (20130101) G01R 33/3415 (20130101) G01R 33/3635 (20130101) G01R 33/3642 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274564 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); KENNEDY KRIEGER INSTITUTE, INC. (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); KENNEDY KRIEGER INSTITUTE, INC. (Baltimore, Maryland) |
INVENTOR(S) | Guanshu Liu (Nottingham, Maryland); Assaf A. Gilad (Baltimore, Maryland); Michael T. McMahon (Columbia, Maryland); Peter C. Van Zijl (Ellicott City, Maryland) |
ABSTRACT | An embodiment in accordance with the present invention provides a method of non-invasively detecting and imaging temperature or temperature changes by assessing the temperature induced shifts in the saturation spectrum of water using MRI, namely saturation shift referencing. This procedure includes the MRI procedures to assess water saturation spectrum and the data processing steps to determine the temperature induced shifts of water resonance frequency and consequently to estimate the temperature change. This procedure also includes the procedure of assessing fat saturation spectrum and estimating fat resonance frequency. This method can be used as a clinical procedure for temperature mapping in multiple applications, especially where a significant amount of fat is present. One application is to monitor the temperature of the targeted tumor and its surrounding tissues during the procedure of hyperthermia. Such local hyperthermia can be applied, using high-intensity focus-ultrasound for deep-seated tissues or heating supplies for superficial tissues. |
FILED | Tuesday, September 17, 2013 |
APPL NO | 14/428713 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/015 (20130101) A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/485 (20130101) G01R 33/4804 (20130101) G01R 33/4828 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10275424 | Friedman |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Carol Friedman (New York, New York) |
ABSTRACT | Improved systems and methods for extracting information from medical and natural-language text data. |
FILED | Tuesday, January 28, 2014 |
APPL NO | 14/166160 |
ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
CURRENT CPC | Electric Digital Data Processing G06F 17/21 (20130101) Original (OR) Class G06F 17/2765 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 10271561 | Omenetto et al. |
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FUNDED BY |
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APPLICANT(S) | TUFTS UNIVERSITY (Medford, Massachusetts) |
ASSIGNEE(S) | Tufts University (Medford, Massachusetts) |
INVENTOR(S) | Fiorenzo Omenetto (Lexington, Massachusetts); David Kaplan (Concord, Massachusetts); Benedetto Marelli (Somerville, Massachusetts); Mark Brenckle (Cambridge, Massachusetts) |
ABSTRACT | Disclosed herein are biopolymer-based coatings and products incorporating such coatings. Related methods and use are also provided. |
FILED | Friday, March 06, 2015 |
APPL NO | 15/121799 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 3/00 (20130101) Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 7/16 (20130101) Original (OR) Class A23B 7/154 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 3/3463 (20130101) A23L 3/3526 (20130101) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Peptides C07K 14/43586 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10271780 | Van Duyne et al. |
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FUNDED BY |
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APPLICANT(S) | Richard P. Van Duyne (Wilmette, Illinois); Matthew R. Glucksberg (Chicago, Illinois); Joseph T. Walsh, Jr. (Evanston, Illinois); Jonathan M. Yuen (Chicago, Illinois); Nilam C. Shah (Chicago, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Richard P. Van Duyne (Wilmette, Illinois); Matthew R. Glucksberg (Chicago, Illinois); Joseph T. Walsh, Jr. (Evanston, Illinois); Jonathan M. Yuen (Chicago, Illinois); Nilam C. Shah (Chicago, Illinois) |
ABSTRACT | The present invention provides systems and methods employing a surface enhanced Raman biosensor and sensing devices for collecting spatially offset Raman spectra from the biosensor. In certain embodiments, the present invention provides systems and methods for quantifying the concentration of an analyte in a subject, and/or identifying the presence or absence of an analyte in a subject, from a plurality of spatially offset Raman spectra generated from a surface enhanced Raman biosensor implanted in a subject. |
FILED | Wednesday, November 23, 2011 |
APPL NO | 13/303815 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1455 (20130101) A61B 5/1459 (20130101) Original (OR) Class A61B 5/14532 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10271855 | Kosiorek et al. |
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FUNDED BY |
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APPLICANT(S) | Christopher B. Kosiorek (La Vernia, Texas); Dexter C. Drayton (San Antonio, Texas); Esra Abir (New York, New York); Neslihan Damar (Istanbul, Turkey); Nilufer Polat (Brooklyn, New York); Yavuz Avci (Sunnyside, New York) |
ASSIGNEE(S) | |
INVENTOR(S) | Christopher B. Kosiorek (La Vernia, Texas); Dexter C. Drayton (San Antonio, Texas); Esra Abir (New York, New York); Neslihan Damar (Istanbul, Turkey); Nilufer Polat (Brooklyn, New York); Yavuz Avci (Sunnyside, New York) |
ABSTRACT | A pre-fabricated pneumatic tourniquet apparatus and related methods are provided. The tourniquet is easy to apply, ensures consistent and even circumferential pressure, is light weight, provides standard life saving operation, and can be utilized in any setting or situation. The pneumatic tourniquet apparatus is comprised of a bladder, a reservoir chassis, a retaining cover, a receiver and a slider. The bladder is elongated in shaped—long enough to wrap around most human limbs. |
FILED | Monday, September 29, 2014 |
APPL NO | 14/500191 |
ART UNIT | 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/135 (20130101) Original (OR) Class A61B 17/1327 (20130101) A61B 90/90 (20160201) A61B 2017/00526 (20130101) A61B 2017/00544 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272096 | Berns et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Michael W. Berns (Irvine, California); Ryan M. Spitler (Costa Mesa, California); Gerard Boss (La Jolla, California) |
ABSTRACT | The invention generally relates to methods for treating and/or reducing the severity of a wound in a subject. Provided are wound therapies combining low level light therapy (LLLT) and a nitric oxide (NO) donor to treat and/or reduce the severity of the wound. The LLLT and NO donor may be administered concurrently or sequentially. Also provided are wound treatment systems and kits including a light source and a NO donor, which are administered to a wounded subject. Further provided are pharmaceutical compositions that comprise a NO donor and are formulated to be administered in conjunction with LLLT. |
FILED | Friday, June 06, 2014 |
APPL NO | 14/894984 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/12 (20130101) A61K 9/0014 (20130101) A61K 31/555 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0613 (20130101) A61N 5/0616 (20130101) A61N 2005/067 (20130101) A61N 2005/0651 (20130101) A61N 2005/0659 (20130101) A61N 2005/0662 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272144 | Kieber-Emmons et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
ASSIGNEE(S) | BioVentures, LLC (Little Rock, Arkansas) |
INVENTOR(S) | Thomas Kieber-Emmons (Little Rock, Arkansas); Anastas Pashov (Little Rock, Arkansas); Behjatolah Karbassi (Little Rock, Arkansas) |
ABSTRACT | Compositions useful to induce anti-TACA immune response and kits comprising the same and methods of using the compositions to treat and prevent cancer are disclosed. Isolated human antibodies which bind to a carbohydrate mimetic peptide and methods of making the same and using the same to treat and prevent cancer are disclosed. Isolated human NK cells useful to kill tumor cells, and isolated human dendritic cells, and methods of making the same and using the same to treat and prevent cancer are disclosed. |
FILED | Thursday, July 31, 2014 |
APPL NO | 14/908503 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/34 (20130101) A61K 31/138 (20130101) A61K 31/138 (20130101) A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/475 (20130101) A61K 31/475 (20130101) A61K 31/675 (20130101) A61K 31/675 (20130101) A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 31/7024 (20130101) A61K 35/15 (20130101) A61K 35/17 (20130101) A61K 39/00 (20130101) A61K 39/0005 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2039/55 (20130101) A61K 2039/507 (20130101) A61K 2039/572 (20130101) A61K 2039/575 (20130101) A61K 2039/585 (20130101) A61K 2039/605 (20130101) A61K 2039/5154 (20130101) A61K 2039/5158 (20130101) A61K 2039/55566 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 7/08 (20130101) C07K 14/4748 (20130101) C07K 16/18 (20130101) C07K 16/32 (20130101) C07K 2317/73 (20130101) C07K 2319/00 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0646 (20130101) C12N 5/0694 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272146 | Sim et al. |
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FUNDED BY |
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APPLICANT(S) | Sanaria Inc. (Rockville, Maryland) |
ASSIGNEE(S) | Sanaria Inc. (Rockville, Maryland) |
INVENTOR(S) | B. Kim Lee Sim (Gaithersburg, Maryland); Minglin Li (Ellicott City, Maryland); Richard E. Stafford (Annandale, Virginia); Stephen L. Hoffman (Gaithersburg, Maryland) |
ABSTRACT | Disclosed are substantially purified Plasmodium sporozoites and preparations of Plasmodium sporozoites substantially separated from attendant non-sporozoite material, where the preparations of Plasmodium sporozoites have increasing levels of purity. Vaccines and pharmaceutical compositions comprising purified Plasmodium sporozoites are likewise provided. Methods of purifying preparations of Plasmodium sporozoites are also provided. |
FILED | Tuesday, March 14, 2017 |
APPL NO | 15/458792 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/4706 (20130101) A61K 39/015 (20130101) Original (OR) Class A61K 2039/522 (20130101) A61K 2039/6081 (20130101) Technologies for Adaptation to Climate Change Y02A 50/412 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272172 | Rangan et al. |
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FUNDED BY |
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APPLICANT(S) | MATERIALS MODIFICATION INC. (Fairfax, Virginia) |
ASSIGNEE(S) | MATERIALS MODIFICATION INC (Fairfax, Virginia) |
INVENTOR(S) | Krishnaswamy Kasthuri Rangan (Fairfax, Virginia); Tirumalai Srinivas Sudarshan (Vienna, Virginia) |
ABSTRACT | A multifunctional polymer-free clay products having a clay, a zwitterion, a silver compound, and, an analgesic. The multifunctional polymer-free clay product provides antimicrobial and pain relieving properties. Method of treatment of burns using the multifunctional polymer-free clay product having antimicrobial and pain relieving properties. Methods of preparing multifunctional polymer-free clay products having a clay, a zwitterion, a silver compound, and, an analgesic. |
FILED | Monday, November 07, 2016 |
APPL NO | 15/345122 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/00063 (20130101) A61F 2013/00157 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/4468 (20130101) A61K 33/38 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/18 (20130101) Original (OR) Class A61L 15/44 (20130101) A61L 15/46 (20130101) A61L 2300/402 (20130101) A61L 2300/404 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272173 | Keyak et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Joyce H. Keyak (Orange, California); Tadashi Kaneko (Irvine, California); Harry B. Skinner (Corona del Mar, California); Varun Sehgal (Irvine, California) |
ABSTRACT | A target tissue can be treated with a radioisotope. Some methods for treating a target tissue with a radioisotope include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material comprises bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement. |
FILED | Monday, March 20, 2017 |
APPL NO | 15/464247 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/1203 (20130101) A61K 51/1279 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/0015 (20130101) Original (OR) Class A61L 2300/44 (20130101) A61L 2300/102 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1014 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272180 | Jiang et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Shaoyi Jiang (Redmond, Washington); Tao Bai (Seattle, Washington); Harihara Subramanian Sundaram (Seattle, Washington); Andrew William Sinclair (Seattle, Washington); Jean-René Ella-Menye (Seattle, Washington); Priyesh Jain (Seattle, Washington) |
ABSTRACT | Functionalized zwitterionic and mixed charge polymers and copolymers, methods for making the polymers and copolymers, hydrogels prepared from the functionalized zwitterionic and mixed charge polymers and copolymers, methods for making and using the hydrogels, and zwitterionic and mixed charge polymers and copolymers for administration for therapeutic agents. |
FILED | Wednesday, September 09, 2015 |
APPL NO | 15/509607 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 47/58 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/22 (20130101) A61L 15/24 (20130101) A61L 15/42 (20130101) A61L 24/0031 (20130101) A61L 24/046 (20130101) A61L 27/16 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/3804 (20130101) A61L 31/06 (20130101) A61L 31/10 (20130101) A61L 31/145 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/36 (20130101) C08F 2220/365 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/021 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 2533/30 (20130101) C12N 2539/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272279 | Hupp et al. |
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FUNDED BY |
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APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
INVENTOR(S) | Joseph T. Hupp (Northfield, Illinois); Omar K. Farha (Morton Grove, Illinois); Michael J. Katz (Evanston, Illinois); Joseph E. Mondloch (Evanston, Illinois) |
ABSTRACT | A method of using a metal organic framework (MOF) comprising a metal ion and an at least bidendate organic ligand to catalytically detoxify chemical warfare nerve agents including exposing the metal-organic-framework (MOF) to the chemical warfare nerve agent and catalytically decomposing the nerve agent with the MOF. |
FILED | Monday, January 23, 2017 |
APPL NO | 15/412412 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 7/10 (20130101) A62B 23/02 (20130101) Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/35 (20130101) Original (OR) Class A62D 9/00 (20130101) A62D 2101/02 (20130101) A62D 2101/26 (20130101) Separation B01D 53/02 (20130101) B01D 53/0415 (20130101) B01D 53/8668 (20130101) B01D 2253/204 (20130101) B01D 2253/306 (20130101) B01D 2253/308 (20130101) B01D 2257/93 (20130101) B01D 2258/0225 (20130101) B01D 2259/4541 (20130101) B01D 2259/4583 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) B01J 31/1691 (20130101) B01J 35/0013 (20130101) B01J 35/023 (20130101) B01J 35/1023 (20130101) B01J 35/1028 (20130101) B01J 35/1061 (20130101) B01J 35/1066 (20130101) B01J 2531/46 (20130101) B01J 2531/48 (20130101) B01J 2531/49 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272382 | She et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Ying She (East Hartford, Connecticut); Aaron T. Nardi (East Granby, Connecticut); Lawrence Binek (Glastonbury, Connecticut); Andrzej Ernest Kuczek (Bristol, Connecticut); Zissis A. Dardas (Worcester, Massachusetts) |
ABSTRACT | A carrier gas recovery system for use in cold spray manufacturing recovers carrier gas utilized during the cold spray process and recycles the carrier gas for immediate use or stores the carrier gas for future use. The carrier gas recovery system includes an enclosure subsystem, a filtration subsystem, a reclamation subsystem, and a compensation subsystem. An article is placed in the enclosure and particulate matter is carried to the article on a carrier gas stream. Carrier gas in the enclosure is filtered through the filtration subsystem to remove particulate from the carrier gas, and the filtered carrier gas is fed to the reclamation subsystem. The carrier gas either flows to a gas separator, to increase the concentration of carrier gas, or to the compensation subsystem if the carrier gas concentration is sufficiently high. The carrier gas can be stored in the compensation subsystem or used in further cold spray manufacturing. |
FILED | Tuesday, May 31, 2016 |
APPL NO | 15/169124 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 53/22 (20130101) B01D 53/30 (20130101) Original (OR) Class B01D 53/047 (20130101) B01D 53/053 (20130101) B01D 53/229 (20130101) B01D 2053/221 (20130101) B01D 2256/10 (20130101) B01D 2257/80 (20130101) B01D 2257/104 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/357 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/00 (20141201) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 24/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272436 | Glezer et al. |
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APPLICANT(S) | Eli N. Glezer (Del Mar, California); Bandele Jeffrey-Coker (Darnestown, Maryland); Kenneth Page (Germantown, Maryland); Sandor Kovacs (Middletown, Delaware); Sudeep Kumar (Gaithersburg, Maryland); Kristian Roth (Germantown, Maryland) |
ASSIGNEE(S) | Meso Scale Technologies, LLC. (Rockville, Maryland) |
INVENTOR(S) | Eli N. Glezer (Del Mar, California); Bandele Jeffrey-Coker (Darnestown, Maryland); Kenneth Page (Germantown, Maryland); Sandor Kovacs (Middletown, Delaware); Sudeep Kumar (Gaithersburg, Maryland); Kristian Roth (Germantown, Maryland) |
ABSTRACT | Assay cartridges are described that have a plurality of chambers and a fluidic network that includes fluidic conduits and a multi-port valve designed to selectively connect the valve inlet and one valve outlet through a fluidic connector in the valve as the remaining valve outlets are sealed. |
FILED | Wednesday, July 03, 2013 |
APPL NO | 14/412866 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/567 (20130101) Original (OR) Class B01L 3/5085 (20130101) B01L 3/502738 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) B01L 2300/0874 (20130101) B01L 2400/0487 (20130101) B01L 2400/0622 (20130101) B01L 2400/0644 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 11/0743 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/2575 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272510 | Verbiscus |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Matthew S. Verbiscus (Dover, New Hampshire) |
ABSTRACT | An EDM machine includes a machine head, a wire guide, a machining wire extending from the wire guide to the machine head, a rotary table mounted to a first surface and a fixed table mounted to the rotary table, and a fixture mounted to the fixed table. The fixture includes a mounting portion substantially circumscribing the fixture. The mounting portion further includes a mounting surface. The mounting surface is closer to a first surface than an upper surface of the fixed table. |
FILED | Thursday, January 14, 2016 |
APPL NO | 14/995448 |
ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Working of Metal by the Action of a High Concentration of Electric Current on a Workpiece Using an Electrode Which Takes the Place of a Tool; Such Working Combined With Other Forms of Working of Metal B23H 1/06 (20130101) B23H 1/028 (20130101) Original (OR) Class B23H 7/06 (20130101) B23H 9/10 (20130101) B23H 11/003 (20130101) Details, Components, or Accessories for Machine Tools, e.g Arrangements for Copying or Controlling; Machine Tools in General Characterised by the Construction of Particular Details or Components; Combinations or Associations of Metal-working Machines, Not Directed to a Particular Result B23Q 3/063 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/285 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273288 | Sullivan et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Institute for Research in Biomedicine (Bellinzona, Switzerland); The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia); Humabs BioMed SA (Bellinzona, Switzerland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Institute for Research in Biomedicine (Bellinzona, Switzerland); The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia); Humabs Biomed SA (Bellinzona, Switzerland) |
INVENTOR(S) | Nancy Sullivan (Kensington, Maryland); Sabue Mulangu (Bethesda, Maryland); Davide Corti (Bellinzona, Switzerland); Antonio Lanzavecchia (Bellinzona, Switzerland); Barney Graham (Rockville, Maryland); Jean-Jacques Muyembe-Tamfun (Kinshasa, Congo); John Trefry (Frederick, Maryland); Julie Ledgerwood (Bethesda, Maryland); Daphne Stanley (Bethesda, Maryland) |
ABSTRACT | Neutralizing antibodies and antigen binding fragments that specifically bind to Ebola virus glycoprotein are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting Ebola virus using the antibodies and antigen binding fragments are disclosed. The antibodies, antigen binding fragments, nucleic acids, and vectors, can be used, for example, to prevent and/or treat Ebola virus infection in a subject. |
FILED | Wednesday, November 14, 2018 |
APPL NO | 16/190676 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/52 (20130101) C07K 2317/56 (20130101) C07K 2317/72 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) C07K 2317/732 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/08 (20130101) G01N 2800/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273327 | Boydston et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Andrew J. Boydston (Seattle, Washington); Kelli Ogawa (Seattle, Washington); Adam E. Goetz (Seattle, Washington); Damian Dunford (Seattle, Washington); Laura Marie Murphy Pascual (Seattle, Washington) |
ABSTRACT | The present disclosure is directed to methods of making a polymer, including exposing a reaction mixture including a strained cyclic unsaturated monomer and an organic initiator to a stimulus to provide an activated organic initiator, whereby the activated organic initiator is effective to polymerize the strained cyclic unsaturated monomer via a 4-membered carbocyclic intermediate to provide a polymer having constitutional units derived from the strained cyclic unsaturated monomer. |
FILED | Thursday, September 03, 2015 |
APPL NO | 15/506578 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/08 (20130101) Original (OR) Class C08G 61/12 (20130101) C08G 61/125 (20130101) C08G 2261/42 (20130101) C08G 2261/44 (20130101) C08G 2261/76 (20130101) C08G 2261/80 (20130101) C08G 2261/135 (20130101) C08G 2261/142 (20130101) C08G 2261/144 (20130101) C08G 2261/1422 (20130101) C08G 2261/1424 (20130101) C08G 2261/3322 (20130101) C08G 2261/3324 (20130101) C08G 2261/3325 (20130101) C08G 2261/3342 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273407 | Collins et al. |
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FUNDED BY |
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APPLICANT(S) | INTELLIGENT MATERIAL SOLUTIONS, INC. (Princeton, New Jersey); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | INTELLIGENT MATERIAL SOLUTIONS, INC. (Princeton, New Jersey); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
INVENTOR(S) | Joshua E. Collins (Philadelphia, Pennsylvania); Howard Y. Bell (Princeton, New Jersey); Xingchen Ye (Philadelphia, Pennsylvania); Christopher Bruce Murray (Montgomery County, Pennsylvania) |
ABSTRACT | Monodisperse particles having: a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology are disclosed. Due to their uniform size and shape, the monodisperse particles self assemble into superlattices. The particles may be luminescent particles such as down-converting phosphor particles and up-converting phosphors. The monodisperse particles of the invention have a rare earth-containing lattice which in one embodiment may be an yttrium-containing lattice or in another may be a lanthanide-containing lattice. The monodisperse particles may have different optical properties based on their composition, their size, and/or their morphology (or shape). Also disclosed is a combination of at least two types of monodisperse particles, where each type is a plurality of monodisperse particles having a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology; and where the types of monodisperse particles differ from one another by composition, by size, or by morphology. In a preferred embodiment, the types of monodisperse particles have the same composition but different morphologies. Methods of making and methods of using the monodisperse particles are disclosed. |
FILED | Thursday, August 30, 2018 |
APPL NO | 16/117453 |
ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 15/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/0031 (20130101) C01F 17/0043 (20130101) C01F 17/0062 (20130101) C01F 17/0087 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/54 (20130101) C01P 2002/72 (20130101) C01P 2002/84 (20130101) C01P 2004/04 (20130101) C01P 2004/10 (20130101) C01P 2004/11 (20130101) C01P 2004/16 (20130101) C01P 2004/20 (20130101) C01P 2004/32 (20130101) C01P 2004/40 (20130101) C01P 2004/42 (20130101) C01P 2004/52 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7773 (20130101) C09K 11/7791 (20130101) Original (OR) Class Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/08 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2933 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273441 | Levner et al. |
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FUNDED BY |
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APPLICANT(S) | EMULATE, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | EMULATE, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Daniel Levner (Brookline, Massachusetts); Josiah Daniel Sliz (Boston, Massachusetts); Christopher David Hinojosa (Cambridge, Massachusetts); Guy Robert Thompson, II (Watertown, Massachusetts); Petrus Wilhelmus Martinus van Ruijven (Glen Waverley, Australia); Matthew Daniel Solomon (Hughesdale, Australia); Christian Alexander Potzner (Port Melbourne, Australia); Patrick Sean Tuohy (St. Kilda, Australia); Joshua Gomes (Somerville, Massachusetts); Norman Wen (West Roxbury, Massachusetts); Jacob Freake (Somerville, Massachusetts); Doug Sabin (Woburn, Massachusetts) |
ABSTRACT | The invention relates to a perfusion manifold assembly that allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with an assembly so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate. The invention further relates to a drop-to-drop connection scheme for putting a microfluidic device in fluidic communication with a fluid source or another microfluidic device, including but not limited to, putting a microfluidic device in fluidic communication with the perfusion manifold assembly. |
FILED | Friday, August 26, 2016 |
APPL NO | 15/248633 |
ART UNIT | 1799 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/021 (20130101) A01N 1/0247 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502738 (20130101) B01L 9/527 (20130101) B01L 2200/12 (20130101) B01L 2200/025 (20130101) B01L 2200/027 (20130101) B01L 2300/14 (20130101) B01L 2300/123 (20130101) B01L 2300/161 (20130101) B01L 2300/165 (20130101) B01L 2300/0681 (20130101) B01L 2300/0887 (20130101) B01L 2400/06 (20130101) B01L 2400/0481 (20130101) B01L 2400/0487 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 23/38 (20130101) C12M 23/40 (20130101) C12M 23/42 (20130101) C12M 29/10 (20130101) C12M 35/04 (20130101) C12M 41/40 (20130101) C12M 41/48 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) C12N 2521/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273582 | Phillips |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jonathan Phillips (Pacific Grove, California) |
ABSTRACT | The disclosure provides a method for generating a metallic coating on a substrate using a mixture comprising a precursor compound typically of chromium oxide, a chemical agent typically comprising NHz, and an inert transport fluid. The precursor compound and chemical agent are generally in the form of particulates having mean diameters less than about 100 microns, and the transport fluid is present in an amount sufficient to facilitate application of the mixture to a substrate. The mixture is applied to a substrate and the coated substrate is heated to a temperature exceeding the decomposition temperature of the chemical agent, generating a reducing gas typically comprising CO, Hx, and/or NHx. In a particular embodiment, the precursor compound is CrO2, Cr3O4, CrO, or mixtures thereof, the chemical agent is urea, and the coated substrate is placed in a reactor having an inert atmosphere and subjected to a temperature of about 700° C. for about 5 minutes while maintaining an inert gas flow through the reactor. |
FILED | Tuesday, August 30, 2016 |
APPL NO | 15/251035 |
ART UNIT | 1718 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/00 (20130101) B22F 9/00 (20130101) B22F 2999/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/02 (20130101) C23C 18/08 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273811 | Lewis |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Scott D. Lewis (Vernon, Connecticut) |
ABSTRACT | A component for use in a turbine engine includes a fore edge connected to an aft edge via a first surface and a second surface. Multiple cooling passages are defined within the turbine engine component. A first skin core passage is defined immediately adjacent one of the first surface and the second surface. At least 80% of coolant entering the first skin core passage is expelled from the turbine engine component at the aft edge. |
FILED | Friday, May 08, 2015 |
APPL NO | 14/707092 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) Original (OR) Class F01D 11/24 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 7/18 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/11 (20130101) F05D 2240/304 (20130101) F05D 2260/203 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/673 (20130101) Y02T 50/676 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273913 | Tuttle |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Steven G. Tuttle (Brandywine, Maryland) |
ABSTRACT | A combustor including a first perforated layer including a first opening having a first diameter, wherein the first opening is configured to receive a flow of fluid including a fuel and air mixture; and impart a first rotational instability to the flow of fluid that is dependent on the first diameter; and a second perforated layer surrounding a combustion area, wherein the second perforated later includes a second opening having a second diameter, and wherein the second layer is located between the first layer and the combustion area. |
FILED | Thursday, May 25, 2017 |
APPL NO | 15/605547 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 27/08 (20130101) Original (OR) Class Methods or Apparatus for Combustion Using Only Solid Fuel F23B 7/002 (20130101) Burners F23D 14/02 (20130101) F23D 14/70 (20130101) F23D 2203/1023 (20130101) Cremation Furnaces; Consuming Waste Products by Combustion F23G 2202/703 (20130101) Casings, Linings, Walls or Doors Specially Adapted for Combustion Chambers, e.g Firebridges; Devices for Deflecting Air, Flames or Combustion Products in Combustion Chambers; Safety Arrangements Specially Adapted for Combustion Apparatus; Details of Combustion Chambers, Not Otherwise Provided for F23M 20/005 (20150115) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/42 (20130101) F23R 3/286 (20130101) F23R 2900/00013 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274377 | Rabb et al. |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | David J. Rabb (Dayton, Ohio); Jason W. Stafford (Dayton, Ohio) |
ABSTRACT | A ladar device that has a linear frequency-modulated laser source that produces a primary beam. An optical shear generator spectrally shears the primary beam into no less than three sensing beams. An optical output delivers at least one of the sensing beams toward a target. The sensing beams reflect from the target to produce reflected beams. An optical receiver receives the reflected beams and produces reflected beam signals corresponding to characteristics of the reflected beams. A processor receives the reflected beam signals and produces a deviation matrix, without the use of a local oscillator. The deviation matrix is used to produce a reconstruction of the target, which is output on an electrical signal output. |
FILED | Thursday, October 12, 2017 |
APPL NO | 15/782327 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02098 (20130101) G01B 11/162 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 9/04 (20130101) G01J 9/0246 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/895 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274404 | Novosselov |
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APPLICANT(S) | SpecTree LLC (Seattle, Washington) |
ASSIGNEE(S) | |
INVENTOR(S) | Igor V Novosselov (Seattle, Washington) |
ABSTRACT | A non-contacting aerodynamic jet tool for collecting particles and vapors associated with surfaces. Opposing planar jets or planar jet arrays are used to liberate material from surfaces so that resuspended particulate matter and vapors can be collected for analysis. In operation, high-speed valves are triggered to create waveforms of high velocity pressurized planar jet bursts. The wall jets that traverse the surfaces exhibit unexpectedly high wall surface stress with velocity spikes characteristic of a chain of shock waves. Unlike axisymmetric jets, the wall jet tool flows over the target surface for a greater distance with wall shear stress having sufficient momentum to dislodge particles submerged in the boundary layer, dramatically improving sampling efficiency by lifting the particles and vapors from the boundary layer into a sampling intake for downstream analysis. |
FILED | Wednesday, February 15, 2017 |
APPL NO | 15/434044 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/005 (20130101) B05B 1/044 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/04 (20130101) G01N 1/24 (20130101) Original (OR) Class G01N 2001/022 (20130101) G01N 2001/028 (20130101) Pictorial Communication, e.g Television H04N 7/183 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274461 | Austin et al. |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Robert H. Austin (Princeton, New Jersey); Zhaoning Yu (Palo Alto, California); Jonas O. Tagenfeldt (Lund, Sweden); Stephen Y. Chou (Princeton, New Jersey); Han Cao (San Diego, California) |
ABSTRACT | Nanochannel arrays that enable high-throughput macromolecular analysis are disclosed. Also disclosed are methods of preparing nanochannel arrays and nanofluidic chips. Methods of analyzing macromolecules, such as entire strands of genomic DNA, are also disclosed, as well as systems for carrying out these methods. |
FILED | Tuesday, June 13, 2017 |
APPL NO | 15/621271 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) G01N 27/44791 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274496 | Raftery et al. |
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APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
INVENTOR(S) | Daniel Raftery (Seattle, Washington); Danijel Djukovic (Seattle, Washington); Haiwei Gu (Seattle, Washington); Jiangjiang Zhu (Seattle, Washington) |
ABSTRACT | A metabolic profiling approach for identifying biomarkers that provide highly sensitive and specific colorectal cancer (CRC) detection and monitoring using serum samples. The methods can be used for distinguishing CRC patients from both healthy controls and polyp patients, as well as to monitor disease progression or response to therapy. Receiver operator characteristic curves generated based on these models showed high sensitivities for differentiating CRC patients from healthy controls or polyp patients, good specificities, low false discovery rates, and excellent areas under the curve were obtained. Monte Carlo cross validation (MCCV) was also applied, demonstrating the robust diagnostic power of this metabolic profiling approach. |
FILED | Friday, January 16, 2015 |
APPL NO | 15/112010 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57419 (20130101) Original (OR) Class G01N 2800/56 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274508 | Barron et al. |
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APPLICANT(S) | Charlie N. Barron (Slidell, Louisiana); Peter L. Spence (Diamondhead, Mississippi); Lucy F. Smedstad (Slidell, Louisiana) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Charlie N. Barron (Slidell, Louisiana); Peter L. Spence (Diamondhead, Mississippi); Lucy F. Smedstad (Slidell, Louisiana) |
ABSTRACT | Embodiments relate to a system and methods for isolating the inertial and non-inertial components of a velocity field in a body of water, and further provides methods for predicting a path of an object in a body of water and for identifying an initial location in the water at which an object should be placed so that it travels to a desired location. The methods in some cases can partition a time series of velocity fields into inertial and non-inertial components in such a way that accounts for the variation of the inertial period over the range of latitudes within the field and maintains the fidelity of non-inertial variability over both shorter and longer time scales. The embodiments seperate the less-reliable inertial components from the more-reliable non-inertial background, enabling straightforward calculation of transport due to the non-inertial flow and evaluation of the superposition of inertial oscillations. |
FILED | Friday, June 05, 2015 |
APPL NO | 14/731493 |
ART UNIT | 2865 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/001 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274548 | Berggren et al. |
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APPLICANT(S) | Susan Anne Elizabeth Berggren (San Diego, California); Robert Lewis Fagaly (Carlsbad, California) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Susan Anne Elizabeth Berggren (San Diego, California); Robert Lewis Fagaly (Carlsbad, California) |
ABSTRACT | A device in accordance with several embodiments can include a plurality of N Superconducting Quantum Interference Devices (SQUIDs), which can be divided into a plurality of sub-blocks of SQUIDs. The SQUIDs in the sub-blocks can be RF SQUIDs, DC SQUIDs or bi-SQUIDs. The sub-blocks can be arranged in a plurality of X tiers, with each Ti tier having a different number of sub-blocks of SQUIDs than an immediately adjacent Ti tier. Each Ti tier can have the same total bias current; and can have SQUIDs with different critical currents and loop sizes, with the different loop sizes on each tier having a Gaussian distribution of between 0.5 and 1.5 (or a random distribution). Additionally, the Arrays can be configured as three independent planar arrays of SQUIDs. The three planar arrays can be triangular when viewed in top plan, and can be arranged so that they are orthogonal to each other. |
FILED | Monday, August 08, 2016 |
APPL NO | 15/230656 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0094 (20130101) G01R 33/0206 (20130101) G01R 33/0354 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274549 | Ledbetter et al. |
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APPLICANT(S) | AOSense, Inc. (Sunnyvale, California) |
ASSIGNEE(S) | AOSense, Inc. (Sunnyvale, California) |
INVENTOR(S) | Micah Ledbetter (Sunnyvale, California); Brian Patton (San Francisco, California) |
ABSTRACT | An atomic magnetometer includes a vapor cell, one or more pumping lasers, a probe laser, and a sensor. The one or more pumping lasers are disposed to direct one or more laser beams though the vapor cell to interact with atoms of an atomic vapor in the vapor cell. The atomic vapor periodically absorbs light of alternating circular polarization from the one or more laser beams. The probe laser is disposed to direct polarized light to pass through the vapor cell. The sensor is disposed to intersect the polarized light from the probe laser after passing through the vapor cell. |
FILED | Wednesday, July 13, 2016 |
APPL NO | 15/209432 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/006 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274606 | Phan et al. |
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FUNDED BY |
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APPLICANT(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
ASSIGNEE(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
INVENTOR(S) | Huan T. Phan (Cedar Rapids, Iowa); Gary A. McGraw (Cedar Rapids, Iowa); Michael J. Armatys (Cedar Rapids, Iowa) |
ABSTRACT | A system and related methods for determining precision navigation solutions decorrelates GPS carrier-phase ambiguities derived from multiple-source GPS information via Least-squares AMBiguity Decorrelation Adjustment (LAMBDA) algorithms, and fixes a subset of the decorrelated integer ambiguities within the LAMBDA domain. To maintain high accuracy, a partial almost fix solution is generated using the subset of the decorrelated ambiguities to be fixed in the LAMBDA domain. The subset of decorrelated ambiguities is used to compute protection levels and the probability of almost fix (PAF), or that the navigation solution corresponding to the decorrelated ambiguities is within the region of correctly-fixed or low-error almost-fixed ambiguities. The partial list of fixed ambiguities is used to generate the optimal navigation solution (floating-point, partial almost-fix, or fully fixed) while maintaining protection levels within alert limits and PAF above the desired threshold. |
FILED | Wednesday, March 09, 2016 |
APPL NO | 15/065260 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/07 (20130101) G01S 19/41 (20130101) G01S 19/44 (20130101) Original (OR) Class G01S 19/48 (20130101) G01S 19/55 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274619 | Gendotti et al. |
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APPLICANT(S) | Arktis Radiation Detectors Ltd. (Zurich, Switzerland) |
ASSIGNEE(S) | ARKTIS RADIATION DETECTORS LTD. (Zurich, Switzerland) |
INVENTOR(S) | Ulisse Gendotti (Zurich, Switzerland); Rico Chandrasekharan (Zurich, Switzerland) |
ABSTRACT | A neutron conversion foil for being used in a neutron detector includes a substrate having a first and second side. The substrate is covered at least on one of the first and second sides with a neutron conversion layer made of a neutron reactive material and being capable of capturing neutrons to thereafter emit light and/or charged particles. The neutron conversion foil is transparent to light such that light originating from the conversion of neutrons can pass through one or several of the neutron conversion foils and thereafter be collected and detected by a light sensing device. |
FILED | Monday, December 21, 2015 |
APPL NO | 15/538389 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/09 (20130101) Measurement of Nuclear or X-radiation G01T 3/06 (20130101) G01T 3/065 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 2004/02 (20130101) G21K 2004/04 (20130101) G21K 2004/10 (20130101) G21K 2004/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274650 | Tabirian et al. |
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APPLICANT(S) | Nelson V. Tabirian (Winter Park, Florida); Svetlana V. Serak (Oviedo, Florida); David E. Roberts (Apopka, Florida); Anna Tabirian (Winter Park, Florida); Diane M. Steeves (Franklin, Massachusetts); Brian R. Kimball (Shrewsbury, Massachusetts) |
ASSIGNEE(S) | Beam Engineering for Advanced Measurements Co. (Winter Park, Florida) |
INVENTOR(S) | Nelson V. Tabirian (Winter Park, Florida); Svetlana V. Serak (Oviedo, Florida); David E. Roberts (Apopka, Florida); Anna Tabirian (Winter Park, Florida); Diane M. Steeves (Franklin, Massachusetts); Brian R. Kimball (Shrewsbury, Massachusetts) |
ABSTRACT | Optical lenses, systems, devices and methods for fabricating and manufacturing diffractive waveplate lenses that allow setting the focal length sign of an optical system by positioning the lens with its front or back surface with respect to an incoming circular polarized light beam. Applications for the lenses include optical systems comprising fibers, diode lasers, waveplates, polarizers, and variable lenses, particularly, in the form of a set of polymer films with re-attachable adhesive layers. And providing a flat mirror with concave or convex function due to diffractive waveplate lens coating. |
FILED | Thursday, April 16, 2015 |
APPL NO | 14/688197 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/1618 (20130101) A61F 2/1654 (20130101) Optical Elements, Systems, or Apparatus G02B 3/10 (20130101) G02B 3/0081 (20130101) G02B 5/001 (20130101) G02B 5/1828 (20130101) G02B 5/1833 (20130101) Original (OR) Class G02B 5/3083 (20130101) G02B 6/024 (20130101) G02B 6/3534 (20130101) G02B 6/3592 (20130101) G02B 27/4205 (20130101) G02B 27/4211 (20130101) G02B 27/4216 (20130101) G02B 27/4261 (20130101) Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 7/10 (20130101) G02C 7/12 (20130101) G02C 7/022 (20130101) G02C 7/061 (20130101) G02C 7/086 (20130101) G02C 2202/16 (20130101) G02C 2202/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274683 | Li et al. |
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APPLICANT(S) | NANOPRECISION PRODUCTS, INC. (El Segundo, California) |
ASSIGNEE(S) | NANOPRECISION PRODUCTS, INC. (Camarillo, California) |
INVENTOR(S) | Shuhe Li (Pasadena, California); Gregory L. Klotz (La Verne, California); Michael K. Barnoski (Pacific Palisades, California); Robert Ryan Vallance (Newbury Park, California) |
ABSTRACT | The present invention provides a spring bias that is particularly suited for use to preload a low profile ferrule of an optical connector. In accordance with the present invention, an axial preload is applied to a connector ferrule by a spring structure provided external of the connector. In one embodiment, spring structure is provided outside a plurality of optical fiber connectors, which provides axial preload of multiple ferrules. Each ferrule could be of the type that supports a plurality of optical fibers of a fiber cable. In one embodiment, the spring bias is effected by a planar flexure external of the connector. The ferrule is coupled to the planar flexure with its longitudinal axis through the center of the planar flexure. The planar flexure is structured with flexure members in a plane that are configured to not create any torque load on the ferrule, or if torque loading is present, insignificant torque load to cause misalignment of the ferrule, when the flexure flexes out of its nominal plane to create an axial preload on the ferrule. In another embodiment, a common yoke is applied to bias planar flexures against a plurality of ferrules, wherein a planar flexure is coupled to each ferrule connector. In a further embodiment of the present invention, instead of using planar flexures, a yoke is provided to apply an axial preload to all ferrule connectors coupled to the yoke, by means of a coil spring applied to center of the yoke, external of the ferrule connectors. |
FILED | Wednesday, December 20, 2017 |
APPL NO | 15/849441 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/3821 (20130101) Original (OR) Class G02B 6/3869 (20130101) G02B 6/3885 (20130101) G02B 6/3887 (20130101) G02B 6/3897 (20130101) G02B 6/4248 (20130101) G02B 6/4292 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274958 | DelMarco et al. |
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APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | Stephen P. DelMarco (North Andover, Massachusetts); Victor T. Tom (Bedford, Massachusetts) |
ABSTRACT | A method for vision-aided navigation which utilizes an image registration system to update a navigation control system. One exemplary feature of the method includes the use of Enhanced Phase Correlation techniques to create a reference imagery database and register images against the created database. The method may be operated on a non-transitory computer-readable medium storing a plurality of instructions which when executed by one or more processors causes the one or more processors to perform the method for vision-aided navigation which utilizes an image registration system to update a navigation control system. |
FILED | Wednesday, November 30, 2016 |
APPL NO | 15/365210 |
ART UNIT | 2485 — Recording and Compression |
CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/005 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/02 (20130101) Original (OR) Class G05D 1/10 (20130101) Electric Digital Data Processing G06F 16/51 (20190101) G06F 16/5838 (20190101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/52 (20130101) Image Data Processing or Generation, in General G06T 7/30 (20170101) G06T 7/32 (20170101) G06T 7/70 (20170101) G06T 2200/28 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10275500 | Chattopadhyay et al. |
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APPLICANT(S) | Cornell University (Ithaca, New York) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Ishanu Chattopadhyay (Ithaca, New York); Hod Lipson (Ithaca, New York) |
ABSTRACT | Data processing including a universal metric to quantify and estimate the similarity and dissimilarity between data sets. Data streams are perfectly annihilated by a correct realization of their anti-streams. Any deviation of the collision product from a baseline, for example flat white noise, quantifies statistical dissimilarity. The invention relates generally to data mining. More specifically, the invention relates to the analysis of data using a universal metric to quantify and estimate the similarity and dissimilarity between sets of data. |
FILED | Friday, September 27, 2013 |
APPL NO | 14/431131 |
ART UNIT | 2165 — Data Bases & File Management |
CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) G06F 17/30539 (20130101) Original (OR) Class G06F 17/30622 (20130101) G06F 17/30864 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00496 (20130101) G06K 9/6201 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10275514 | Beller et al. |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Charles E. Beller (Baltimore, Maryland); Sean L. Bethard (Centreville, Virginia); William G. Dubyak (Severna Park, Maryland); Alexander C. Tonetti (Washington, District of Columbia); Sean T. Thatcher (Stone Ridge, Virginia); Julie T. Yu (Centreville, Virginia) |
ABSTRACT | Embodiments can provide a computer implemented method, in a data processing system comprising a processor and a memory comprising instructions which are executed by the processor to cause the processor to implement an improved search query generation system, the method comprising inputting a natural language question; parsing the natural language question into a parse tree; identifying argument positions comprising one or more argument position terms; for each argument position: comparing a head term's discriminator score against a threshold discriminator score; and if the head term surpasses the threshold discriminator score, adding the head term as a required term to an improved search query; and outputting the improved search query. |
FILED | Tuesday, November 22, 2016 |
APPL NO | 15/359010 |
ART UNIT | 2168 — Data Bases & File Management |
CURRENT CPC | Electric Digital Data Processing G06F 17/30654 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10275656 | Castanon et al. |
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FUNDED BY |
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APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
INVENTOR(S) | Gregory D. Castanon (Jamaica Plain, Massachusetts); Venkatesh Saligrama (Newton, Massachusetts); Ziming Zhang (Boston, Massachusetts); Yuting Chen (Framingham, Massachusetts) |
ABSTRACT | One embodiment of the present solution is a relationship-based video server system. The server system is programmed to provide a platform for large scale video search based on relationships between objects in video segments, and the platform executes search based on probabilistically discriminative objects and relationships. |
FILED | Friday, November 20, 2015 |
APPL NO | 15/526670 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Electric Digital Data Processing G06F 17/3079 (20130101) G06F 17/30017 (20130101) G06F 17/30864 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00677 (20130101) G06K 9/00758 (20130101) Original (OR) Class G06K 9/00785 (20130101) G06K 9/4652 (20130101) G06K 9/6282 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10275668 | Nuernberger et al. |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Benjamin Nuernberger (Granada Hills, California); Deepak Khosla (Camarillo, California); Kyungnam Kim (Oak Park, California); Yang Chen (Westlake Village, California); Fredy Monterroza (Canoga Park, California) |
ABSTRACT | Described is a system for collision detection and avoidance estimation using sub-region based optical flow. During operation, the system estimates time-to-contact (TTC) values for an obstacle in multiple regions-of-interest (ROI) in successive image frames as obtained from a monocular camera. Based on the TTC values, the system detects if there is an imminent obstacle. If there is an imminent obstacle, a path for avoiding the obstacle is determined based on the TTC values in the multiple ROI. Finally, a mobile platform is caused to move in the path as determined to avoid the obstacle. |
FILED | Tuesday, September 20, 2016 |
APPL NO | 15/271025 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Aeroplanes; Helicopters B64C 2201/024 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00805 (20130101) Original (OR) Class G06K 9/2054 (20130101) Image Data Processing or Generation, in General G06T 7/0024 (20130101) G06T 7/2066 (20130101) G06T 2207/10016 (20130101) Pictorial Communication, e.g Television H04N 7/183 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10275718 | Kerman |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Andrew J. Kerman (Arlington, Massachusetts) |
ABSTRACT | Described herein are structures and techniques for highly-connected qubit interaction using a “paramagnetic tree coupling” scheme. In one embodiment, a structure for providing highly-connected qubit interaction includes a plurality of qubits and, for each of the plurality of qubits, a paramagnetic medium connecting the qubit to each other one of the plurality of qubits, where the paramagnetic medium includes a series of inductive couplers. |
FILED | Thursday, November 17, 2016 |
APPL NO | 15/354286 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276312 | Kumar et al. |
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APPLICANT(S) | Satish Kumar (Atlanta, Georgia); Kishor Kumar Gupta (Duluth, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Satish Kumar (Atlanta, Georgia); Kishor Kumar Gupta (Duluth, Georgia) |
ABSTRACT | In a method of making a high surface area carbon material, a precursor organic material is prepared. The precursor organic material is subjected to a first elevated temperature while applying a gaseous purge thereto for a first predetermined time. The precursor organic material is subjected to a second elevated temperature while not applying the gaseous purge thereto for a second predetermined time after the first predetermined time. A high surface area carbon material includes carbon and has a surface area in a range between 3029 m2/g to 3565 m2/g and a pore volume in a range between 1.66 cm3/g and 1.90 cm3/g. The high surface area carbon material may be employed in an electrode for a supercapacitor. |
FILED | Friday, April 28, 2017 |
APPL NO | 15/581929 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/05 (20170801) C01B 32/30 (20170801) C01B 32/342 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/12 (20130101) C01P 2006/14 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) H01G 11/32 (20130101) Original (OR) Class H01G 11/34 (20130101) H01G 11/44 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7022 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276735 | Allen et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Peter Matthew Allen (Cambridge, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts) |
ABSTRACT | A semiconductor nanocrystal include a first I-III-VI semiconductor material and have a luminescence quantum yield of at least 10%, at least 20%, or at least 30%. The nanocrystal can be substantially free of toxic elements. Populations of the nanocrystals can have an emission FWHM of no greater than 0.35 eV. |
FILED | Wednesday, July 26, 2017 |
APPL NO | 15/660930 |
ART UNIT | 2829 — Semiconductors/Memory |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/002 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/52 (20130101) C01P 2004/64 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/58 (20130101) C09K 11/62 (20130101) C09K 11/88 (20130101) C09K 11/565 (20130101) C09K 11/584 (20130101) C09K 11/623 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0749 (20130101) H01L 31/03529 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/541 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276740 | Ayachitula et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Rajani Ayachitula (Colorado Springs, Colorado); Kimberly D. de La Harpe (Manitou Springs, Colorado); Daniel E. Weisz (Centreville, Virginia); John M. Testerman (Columbus AFB, Mississippi); William J. Mandeville (Monument, Colorado); Randall J. Knize (Colorado Springs, Colorado); Brian M. Patterson (Colorado Springs, Colorado) |
ABSTRACT | A method for forming a photon absorbing layer. A substrate having a target surface is introduced into a controllable environment, and the pressure within the controllable environment is reduced. A first flux of a semiconductor material and a second flux of a dopant are simultaneously directed toward the target surface for a period of time, thereby producing a thickness of a substantially amorphous layer of the semiconductor material and dopant on the target surface. The semiconductor layer is laser annealed to convert it to a substantially multi-crystalline layer. |
FILED | Monday, March 19, 2018 |
APPL NO | 15/925187 |
ART UNIT | 2895 — Semiconductors/Memory |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/14 (20130101) C23C 14/24 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0257 (20130101) H01L 21/02532 (20130101) H01L 21/02592 (20130101) H01L 21/02625 (20130101) H01L 21/02686 (20130101) H01L 31/182 (20130101) Original (OR) Class H01L 31/0288 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276817 | Forrest et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | University of Southern California (Los Angeles, California); The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Quinn Burlingame (Ann Arbor, Michigan); Xin Xiao (Ann Arbor, Michigan); Kevin Bergemann (Ann Arbor, Michigan); Anurag Panda (Ann Arbor, Michigan); Jeramy D. Zimmerman (Golden, Colorado); Brian E. Lassiter (San Francisco, California); Mark E. Thompson (Anaheim, California); Andrew N. Bartynski (Los Angeles, California); Cong Trinh (San Jose, California) |
ABSTRACT | Disclosed herein are stable organic photosensitive devices including at least one exciton-blocking charge carrier filter. The filters comprise a mixture of at least one wide energy gap material having a sufficiently high glass transition temperature, e.g., higher than the temperature or temperature range at which the device typically operates, higher than a highest operating temperature of the device, higher than a threshold temperature value, etc. and at least one electron or hole conducting material. As described herein, the novel filters simultaneously block excitons and conduct the desired charge carrier (electrons or holes). |
FILED | Monday, July 20, 2015 |
APPL NO | 14/803643 |
ART UNIT | 2895 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/006 (20130101) H01L 51/0046 (20130101) H01L 51/0058 (20130101) H01L 51/0059 (20130101) H01L 51/0072 (20130101) H01L 51/0081 (20130101) H01L 51/4246 (20130101) H01L 51/4273 (20130101) Original (OR) Class H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276931 | Wunsch |
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FUNDED BY |
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APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | Gregory J. Wunsch (Milford, New Hampshire) |
ABSTRACT | A reduced profile panel antenna is disclosed. A panel antenna configured according to an embodiment includes two opposing antenna arms disposed over a ground plane. The antenna arms include one or more corrugated or folded sections to increase the electrical path of the antenna arms within fixed physical dimensions (e.g., length and width) of the panel antenna. The panel antenna also includes passive filters to provide current loop paths of varying lengths for selected frequency ranges. Longer loop paths are employed for signals at lower frequencies (i.e., longer wavelengths) and shorter loop paths are employed for signals at higher frequencies (i.e., shorter wavelengths). The panel antenna further includes a ferrite plane disposed between the ground plane and the antenna arms to suppress radio frequency (RF) signal reflections and allow for a reduced antenna profile or thickness. |
FILED | Wednesday, December 13, 2017 |
APPL NO | 15/840387 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/22 (20130101) H01Q 1/38 (20130101) Original (OR) Class H01Q 1/242 (20130101) H01Q 5/25 (20150115) H01Q 5/357 (20150115) H01Q 5/378 (20150115) H01Q 7/00 (20130101) H01Q 9/0421 (20130101) H01Q 9/0442 (20130101) H01Q 11/14 (20130101) H01Q 13/10 (20130101) H01Q 13/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276945 | Komiak |
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FUNDED BY |
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APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | James J. Komiak (Merrimack, New Hampshire) |
ABSTRACT | A phased array antenna which can change the configuration of the phased array antenna by controllable quad switches on the phased array antenna is presented. The phased array antenna adapts monolithic microwave integrate circuit (MMIC) technology to have high isolation interconnection of the reconfigurable phased array antenna. The reconfigurable phased array antenna can be reusable and adaptable to different configurations so that the overall cost and lead time of the phased array antenna is reduced compared to the existing RF antennas in the market. |
FILED | Thursday, April 14, 2016 |
APPL NO | 15/098510 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/281 (20130101) H01Q 21/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276999 | Rotondaro et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Matthew D. Rotondaro (Colorado Springs, Colorado); Randal J. Knize (Colorado Springs, Colorado); Boris Zhdanov (Colorado Springs, Colorado) |
ABSTRACT | An optically pumped, flowing gas, alkali metal laser includes a gas passageway transporting an alkali metal vapor and a hydrocarbon buffer gas, and a laser propagation passageway intersects the gas passageway and forms a main cell at the intersection. A pump laser is directed into the main cell and produces a main laser beam in the laser propagation passageway. The flowing hydrocarbon buffer gas is disposed in the main cell with a density to induce spin-orbit relaxation in the alkali metal vapor. At least one window is disposed in the laser propagation passageway, and the window is protected from deposits of alkali metal or carbon by a heated leading edge in the laser propagation passageway that re-vaporizes alkali metal and returns it to the gas passageway via a convective gas flow. The window is further protected by a cold block that liquefies alkali metal and by a colder block that solidifies alkali metal in the laser propagation passageway. |
FILED | Wednesday, January 17, 2018 |
APPL NO | 15/873612 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/031 (20130101) Original (OR) Class H01S 3/041 (20130101) H01S 3/094 (20130101) H01S 3/227 (20130101) H01S 3/0346 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277005 | Jeschke et al. |
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FUNDED BY |
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APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
INVENTOR(S) | Jorg Jeschke (Berlin, Germany); Thomas Wunderer (Santa Cruz, California); Mark Teepe (Menlo Park, California) |
ABSTRACT | An edge emitting structure includes an active region configured to generate radiation in response to excitation by a pumping beam incident on the structure. A front facet of the edge emitting structure is configured to emit the radiation generated by the active region. A metallic reflective coating disposed on at least one of the front and rear facets of the edge emitting structure. The metallic reflective coating is configured to reflect the radiation generated by the active region. |
FILED | Wednesday, September 13, 2017 |
APPL NO | 15/703534 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0959 (20130101) H01S 5/04 (20130101) H01S 5/0287 (20130101) Original (OR) Class H01S 5/2018 (20130101) H01S 5/3211 (20130101) H01S 5/4031 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277204 | Zhou et al. |
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FUNDED BY |
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APPLICANT(S) | Jin Zhou (New York, New York); Harish Krishnaswamy (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Jin Zhou (New York, New York); Harish Krishnaswamy (New York, New York) |
ABSTRACT | Self-interference cancellers are provided. The self-interference cancellers can include multiple second-order, N-path Gm-C filters. Each filter can be configured to cancel self-interference on a channel of a desired bandwidth. Each filter can be independently controlled using a variable transmitter resistance, a variable receiver resistance, a variable baseband capacitance, a variable transconductance, and a variable time shift between local oscillators that control switches in the filter. By controlling these variables, magnitude, phase, slope of magnitude, and slope of phase of the cancellers frequency responses can be controlled for self-interference cancellation. A calibration process is also provided for configuring the canceller. |
FILED | Thursday, October 01, 2015 |
APPL NO | 15/515823 |
ART UNIT | 2631 — Digital Communications |
CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 19/002 (20130101) Original (OR) Class H03H 2210/021 (20130101) H03H 2210/025 (20130101) H03H 2210/028 (20130101) Transmission H04B 1/525 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/03006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277247 | Kingston et al. |
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FUNDED BY |
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APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | Peter M. Kingston (Somerville, Massachusetts); Lingji Chen (Acton, Massachusetts); Eric N. Duchon (Arlington, Massachusetts); Christopher D. Moss (Cambridge, Massachusetts) |
ABSTRACT | A receiver includes: a filter circuit to generate predicted measurements for a set of tracks based on previous kinematic states of the tracks and timing and source data of next compressed measurements associated to the tracks, generate probability data of differences between the predicted measurements and next measurement data, generate the next measurement data using the predicted measurements and quantized differences between the predicted measurements and the next measurement data, and generate next kinematic states of the tracks based on the previous kinematic states, the timing and source data of the next compressed measurements, and the generated measurement data; a quantizer circuit to quantize the probability data into quantization tables and look up the quantized differences from corresponding indices in the quantization tables; and a decoder circuit to decode encoded index data of the next compressed measurements into the corresponding indices in the quantization tables using the quantized probability data. |
FILED | Wednesday, April 11, 2018 |
APPL NO | 15/950913 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 7/3071 (20130101) H03M 7/4018 (20130101) Original (OR) Class H03M 7/6035 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277316 | Sedillo |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Michael R Sedillo (Dayton, Ohio) |
ABSTRACT | A communications headset system and method of use utilizing first and second headsets with integrated hearing protection for enabling users to wirelessly communicate when the hearing protection is engaged. Each headset is configured for placement onto a user's head and includes hearing protection cups that engage a user's ears and attenuate incoming sound waves external to the headset. The headsets include a first optical receiver that detects a light signal within a first receiving field-of-view and generates an incoming electrical signal corresponding to the light signal. A speaker converts the incoming electrical signal to an incoming audio signal, and then outputs the incoming audio signal as sound waves. A microphone converts outgoing sound waves to an outgoing electrical signal. An optical transmitter converts the outgoing electrical signal to one or more light signals and then broadcasts the one or more light signals within a broadcast field-of-view and a broadcast range. |
FILED | Monday, May 01, 2017 |
APPL NO | 15/583311 |
ART UNIT | 2633 — Digital Communications |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 11/08 (20130101) A61F 11/14 (20130101) A61F 2011/145 (20130101) Transmission H04B 10/40 (20130101) H04B 10/114 (20130101) Original (OR) Class Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/028 (20130101) H04R 2499/11 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277324 | Morton et al. |
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FUNDED BY |
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APPLICANT(S) | Morton Photonics (West Friendship, Maryland) |
ASSIGNEE(S) | Morton Photonics (West Friendship, Maryland) |
INVENTOR(S) | Paul A. Morton (West Friendship, Maryland); Jacob Khurgin (Pikesville, Maryland) |
ABSTRACT | High-performance ultra-wideband Phased Array Sensors (PAS) are disclosed, which have unique capabilities, enabled through photonic integrated circuits and novel optical architectures. Unique capabilities for a Receive PAS are provided by wafer scale photonic integration including heterogeneous integration of III-V materials and ultra-low-loss silicon nitride waveguides, combining key component technologies into complex PIC devices. Novel aspects include optical multiplexing combining wavelength division multiplexing and/or a novel extension to array photodetectors providing the capability to combine many RF photonic signals with very low loss. The architecture also includes optical down-conversion, as well as digital signal processing to improve the linearity of the system. Simultaneous multi-channel beamforming is achieved through optical power splitting of optical signals to create multiple exact replicas of the signals that are then processed independently. |
FILED | Wednesday, October 10, 2018 |
APPL NO | 16/156087 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/2676 (20130101) Transmission H04B 10/50 (20130101) H04B 10/516 (20130101) H04B 10/25759 (20130101) Original (OR) Class H04B 2210/006 (20130101) Selecting H04Q 5/00 (20130101) H04Q 11/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10278275 | Imhof |
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FUNDED BY |
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APPLICANT(S) | Utah State University Research Foundation (North Logan, Utah) |
ASSIGNEE(S) | Utah State University Research Foundation (Logan, Utah) |
INVENTOR(S) | Eric Imhof (Albuquerque, New Mexico) |
ABSTRACT | A two-dimensional magneto-optical trap (2D GMOT) that is configured to produce a cold-atom beam exiting the 2D GMOT is disclosed. In embodiments, the 2D GMOT is configured to feed a three-dimensional GMOT with the cold atom beam. In embodiments, the 2D GMOT includes an input light beam having its direction along a first axis, its width along a second axis, normal to the first axis, and a substantially flat input light beam intensity profile. 2D GMOT may further includes a quadrupole magnetic field with its magnitude being zero along a third axis that is centered at the center of the input light beam's width. The 2D GMOT may also include a diffraction-grating surface positioned normal to the first axis, composed of closely adjacent parallel grooves spread across the width and run parallel to the third axis. |
FILED | Monday, February 13, 2017 |
APPL NO | 15/431492 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/4233 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 3/02 (20130101) H05H 3/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 10272182 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Xi Chelsea Chen (Berkeley, California); Jeffrey Yang (San Francisco, California); Albert Chin (Palo Alto, California); Anand Patel (San Francisco, California); Steven Hetts (San Francisco, California); Nitash Balsara (El Cerrito, California) |
ABSTRACT | Described herein is a porous copolymer membrane composed of poly(styrene sulfonate)-block-polyethylene-block-poly(styrenesulfonate) for use in the absorption of doxorubicin, and a chemofiltration catheter incorporating the membrane for use in transarterial chemoembolization. |
FILED | Monday, October 12, 2015 |
APPL NO | 14/880925 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/041 (20130101) Original (OR) Class A61L 29/041 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3615 (20140204) A61M 2207/00 (20130101) Separation B01D 69/02 (20130101) B01D 71/26 (20130101) B01D 71/66 (20130101) B01D 71/80 (20130101) B01D 2325/02 (20130101) B01D 2325/04 (20130101) B01D 2325/20 (20130101) Compositions of Macromolecular Compounds C08L 53/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272279 | Hupp et al. |
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FUNDED BY |
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APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
INVENTOR(S) | Joseph T. Hupp (Northfield, Illinois); Omar K. Farha (Morton Grove, Illinois); Michael J. Katz (Evanston, Illinois); Joseph E. Mondloch (Evanston, Illinois) |
ABSTRACT | A method of using a metal organic framework (MOF) comprising a metal ion and an at least bidendate organic ligand to catalytically detoxify chemical warfare nerve agents including exposing the metal-organic-framework (MOF) to the chemical warfare nerve agent and catalytically decomposing the nerve agent with the MOF. |
FILED | Monday, January 23, 2017 |
APPL NO | 15/412412 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 7/10 (20130101) A62B 23/02 (20130101) Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/35 (20130101) Original (OR) Class A62D 9/00 (20130101) A62D 2101/02 (20130101) A62D 2101/26 (20130101) Separation B01D 53/02 (20130101) B01D 53/0415 (20130101) B01D 53/8668 (20130101) B01D 2253/204 (20130101) B01D 2253/306 (20130101) B01D 2253/308 (20130101) B01D 2257/93 (20130101) B01D 2258/0225 (20130101) B01D 2259/4541 (20130101) B01D 2259/4583 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) B01J 31/1691 (20130101) B01J 35/0013 (20130101) B01J 35/023 (20130101) B01J 35/1023 (20130101) B01J 35/1028 (20130101) B01J 35/1061 (20130101) B01J 35/1066 (20130101) B01J 2531/46 (20130101) B01J 2531/48 (20130101) B01J 2531/49 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273156 | Gupta et al. |
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FUNDED BY |
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APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
INVENTOR(S) | Shalabh Gupta (Ames, Iowa); Vitalij K. Pecharsky (Ames, Iowa); Takeshi Kobayashi (Ames, Iowa); Marek Pruski (Ames, Iowa); Ihor Hlova (Ames, Iowa) |
ABSTRACT | In some examples, a method of forming alane (AlH3), the method comprising reacting one of: 1) a MAlH4, wherein M is an alkali metal; 2) alkali-metal hydride, MH; or 3) alkali-metal with one or more aluminum halides (AlX3, where X is a halogen), via a mechanochemical process, to form the alane, wherein the reaction is substantially solvent free and carried out in an environment with a temperature between approximately 250 K and approximately 330 K. |
FILED | Thursday, February 12, 2015 |
APPL NO | 15/118788 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/0026 (20130101) C01B 6/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273403 | Luther et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Abhishek Swarnkar (Jharkhand, India); The Regents of the University of Colorado, a body corporate (Denver, Colorado); University of Washington (Seattle, Washington) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); University of Washington (Seattle, Washington); Regents of the University of Colorado, a body corporate (Denver, Colorado) |
INVENTOR(S) | Joseph Matthew Luther (Boulder, Colorado); Abhishek Swarnkar (Jharkhand, India); Ashley Rae Marshall (Golden, Colorado); Erin Mariko Sanehira (Lakewood, Colorado) |
ABSTRACT | The present disclosure relates to a composition that includes a particle and a surface species, where the particle has a characteristic length between greater than zero nm and 100 nm inclusively, and the surface species is associated with a surface of the particle such that the particle maintains a crystalline form when the composition is at a temperature between −180° C. and 150° C. |
FILED | Wednesday, May 31, 2017 |
APPL NO | 15/609401 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/22 (20130101) C09D 5/24 (20130101) C09D 7/67 (20180101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) Original (OR) Class C09K 11/665 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/20 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02167 (20130101) H01L 31/035218 (20130101) H01L 33/04 (20130101) H01L 33/44 (20130101) H01L 51/426 (20130101) H01L 51/448 (20130101) H01L 51/5237 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/95 (20130101) Y10S 977/774 (20130101) Y10S 977/825 (20130101) Y10S 977/896 (20130101) Y10S 977/948 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273405 | Weidman et al. |
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FUNDED BY |
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APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Mark Clayton Weidman (Cambridge, Massachusetts); Michael Seitz (Meilen, Switzerland); William Alfred Tisdale (Belmont, Massachusetts) |
ABSTRACT | Colloidal perovskite nanoplatelets can provide a material platform, with tunability extending from the deep UV, across the visible, into the near-IR. The high degree of spectral tunability can be achieved through variation of the cation, metal, and halide composition as well as nanoplatelet thickness. |
FILED | Wednesday, May 03, 2017 |
APPL NO | 15/585912 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/5152 (20130101) C04B 2235/768 (20130101) C04B 2235/3201 (20130101) C04B 2235/3293 (20130101) C04B 2235/3296 (20130101) C04B 2235/5292 (20130101) C04B 2235/5454 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/24 (20130101) C07F 7/2208 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class C09K 11/025 (20130101) C09K 11/665 (20130101) C09K 2211/181 (20130101) C09K 2211/188 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/20 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/52 (20130101) H01L 51/0077 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273407 | Collins et al. |
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APPLICANT(S) | INTELLIGENT MATERIAL SOLUTIONS, INC. (Princeton, New Jersey); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | INTELLIGENT MATERIAL SOLUTIONS, INC. (Princeton, New Jersey); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
INVENTOR(S) | Joshua E. Collins (Philadelphia, Pennsylvania); Howard Y. Bell (Princeton, New Jersey); Xingchen Ye (Philadelphia, Pennsylvania); Christopher Bruce Murray (Montgomery County, Pennsylvania) |
ABSTRACT | Monodisperse particles having: a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology are disclosed. Due to their uniform size and shape, the monodisperse particles self assemble into superlattices. The particles may be luminescent particles such as down-converting phosphor particles and up-converting phosphors. The monodisperse particles of the invention have a rare earth-containing lattice which in one embodiment may be an yttrium-containing lattice or in another may be a lanthanide-containing lattice. The monodisperse particles may have different optical properties based on their composition, their size, and/or their morphology (or shape). Also disclosed is a combination of at least two types of monodisperse particles, where each type is a plurality of monodisperse particles having a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology; and where the types of monodisperse particles differ from one another by composition, by size, or by morphology. In a preferred embodiment, the types of monodisperse particles have the same composition but different morphologies. Methods of making and methods of using the monodisperse particles are disclosed. |
FILED | Thursday, August 30, 2018 |
APPL NO | 16/117453 |
ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 15/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/0031 (20130101) C01F 17/0043 (20130101) C01F 17/0062 (20130101) C01F 17/0087 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/54 (20130101) C01P 2002/72 (20130101) C01P 2002/84 (20130101) C01P 2004/04 (20130101) C01P 2004/10 (20130101) C01P 2004/11 (20130101) C01P 2004/16 (20130101) C01P 2004/20 (20130101) C01P 2004/32 (20130101) C01P 2004/40 (20130101) C01P 2004/42 (20130101) C01P 2004/52 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7773 (20130101) C09K 11/7791 (20130101) Original (OR) Class Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/08 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2933 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273506 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Taek Soon Lee (Berkeley, California); Aram Kang (Richmond, California) |
ABSTRACT | The present invention provides for a genetically modified host cell capable of producing isopentenol and/or 3-methyl-3-butenol, comprising (a) an increased expression of phosphomevalonate decarboxylase (PMD) (b) an increased expression of a phosphatase capable of converting isopentenol into 3-methyl-3-butenol, (c) optionally the genetically modified host cell does not express, or has a decreased expression of one or more of NudB, phosphomevalonate kinase (PMK), and/or PMD, and (d) optionally one or more further enzymes capable of converting isopentenol and/or 3-methyl-3-butenol into a third compound, such as isoprene. |
FILED | Monday, August 21, 2017 |
APPL NO | 15/682325 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/091 (20130101) C07F 9/098 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 136/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/16 (20130101) C12N 9/88 (20130101) C12N 9/1025 (20130101) C12N 9/1205 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/007 (20130101) C12P 7/04 (20130101) Original (OR) Class Enzymes C12Y 101/01088 (20130101) C12Y 203/0301 (20130101) C12Y 207/01036 (20130101) C12Y 401/01033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273511 | Lemke et al. |
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APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Rachelle A. S. Lemke (Madison, Wisconsin); Timothy James Donohue (Middleton, Wisconsin); Joshua J. Coon (Middleton, Wisconsin); Amelia C. Peterson (Bremen, Germany); Michael S. Westphall (Fitchburg, Wisconsin) |
ABSTRACT | Enzymes for producing non-straight-chain fatty acids, microorganisms comprising the enzymes, and in vivo and in vitro uses of the enzymes. Provided are enzymes capable of producing various non-straight-chain fatty acids, including branched-chain fatty acids, cyclic fatty acids, and furan-containing fatty acids. The enzymes include RSP2144, RSP1091, and RSP1090 from Rhodobacter sphaeroides and homologs thereof. The enzymes can be purified to produce non-straight-chain fatty acids in vitro or expressed in microorganisms to produce non-straight-chain fatty acids in vivo. The microorganisms can be fine-tuned to produce a specific type of non-straight-chain fatty acid by expressing, overexpressing, or deleting the enzymes in various combinations. |
FILED | Tuesday, June 30, 2015 |
APPL NO | 14/755213 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1007 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class C12P 17/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273586 | Roemer et al. |
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FUNDED BY |
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APPLICANT(S) | PROTON ENERGY SYSTEMS, INC. (Wallingford, Connecticut) |
ASSIGNEE(S) | PROTON ENERGY SYSTEMS, INC. (Wallingford, Connecticut) |
INVENTOR(S) | Andrew Roemer (Pomfret Center, Connecticut); Blake Carter (Middletown, Connecticut); Luke Dalton (Cromwell, Connecticut) |
ABSTRACT | A separator plate and a frame member for an electrochemical cell are provided. The separator plate includes a plurality of protrusions extending therefrom to define a flow field. A pair of end features arranged along opposite sides of the flow field, each end feature extending substantially the length of the flow field. A periphery portion is provided having a first set of openings and a second set of openings. Wherein the plurality of protrusions and pair of end features extend from a plane defined by the periphery portion. The frame member includes features for facilitating assembly and reducing the risk of an over constrained condition. The frame member further having ports divided by a bridge member to support the frame member under operating pressures. |
FILED | Thursday, February 12, 2015 |
APPL NO | 14/620619 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/08 (20130101) C25B 1/10 (20130101) Original (OR) Class C25B 9/04 (20130101) C25B 9/08 (20130101) C25B 9/18 (20130101) C25B 9/20 (20130101) C25B 13/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/026 (20130101) H01M 8/0206 (20130101) H01M 8/242 (20130101) H01M 8/0258 (20130101) H01M 8/0273 (20130101) H01M 8/2465 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/366 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273593 | Kwon et al. |
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APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Gihan Kwon (Lemont, Illinois); Jonathan D. Emery (Chicago, Illinois); In Soo Kim (Woodridge, Illinois); Alex B. Martinson (Naperville, Illinois); David M. Tiede (Elmhurst, Illinois) |
ABSTRACT | An electrochemical cell that allows for in-situ structural characterization of amorphous thin film materials during the course of electrolysis using high-energy X-ray scattering (>50 keV). The compact and versatile cell employs a three-electrode configuration and minimizes X-ray scattering contributions from the cell, reference and counter electrodes, as well as the working electrode support. A large surface area working electrode has a physically robust support and is largely transparent to X-rays. This design, which utilizes a three-dimensional working electrode, also greatly improves the intensity and quality of the scattered signal compared to a two-dimensional working electrode. The in-situ cell can be used not only to investigate structural evolution during electrolysis using X-ray scattering (e.g. pair distribution function), but also to perform electrochemical potential-dependent structural analysis by extended X-ray absorption fine structure. |
FILED | Wednesday, July 27, 2016 |
APPL NO | 15/221167 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 9/06 (20130101) C25D 17/00 (20130101) C25D 17/02 (20130101) C25D 17/12 (20130101) Original (OR) Class C25D 21/12 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20 (20130101) G01N 2223/61 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273792 | Mace et al. |
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FUNDED BY |
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APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Jonathan Lee Mace (Los Alamos, New Mexico); Lawrence E. Bronisz (Los Alamos, New Mexico); David W. Steedman (Santa Fe, New Mexico); Christopher Robert Bradley (Chimayo, New Mexico) |
ABSTRACT | Explosive geologic fracturing methods, devices, and systems can be used in combination with other geologic fracturing means, such as hydraulic fracturing methods, devices and systems, or other fluid-based fracturing means. An exemplary method comprises introducing an explosive system into a wellbore in a geologic formation, detonating the explosive system in the wellbore to fracture at least a first portion of the geologic formation adjacent to the wellbore, and introducing pressurized fluid into the wellbore to enhance the fracturing of the first portion of the geologic formation. Such multi-stage fracturing can further enhance the resulting fracturing of geologic formation relative to explosive fracturing alone. |
FILED | Tuesday, July 15, 2014 |
APPL NO | 14/905356 |
ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/26 (20130101) E21B 43/263 (20130101) Original (OR) Class Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/02 (20130101) Blasting F42D 1/22 (20130101) F42D 3/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273813 | Kittleson et al. |
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APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
INVENTOR(S) | Jacob John Kittleson (Greenville, South Carolina); James Joseph Murray, III (Piedmont, South Carolina) |
ABSTRACT | A process of producing a ceramic matrix composite component. The process includes positioning core plies on a mandrel. At least partially rigidizing the core plies to form a preform ceramic matrix composite arrangement defining a tip cavity and a hollow region. Ceramic matrix composite tip plies are positioned on the preform ceramic matrix composite arrangement and within the tip cavity. The ceramic matrix composite tip plies are densified to form a tip region of the composite component. |
FILED | Thursday, October 29, 2015 |
APPL NO | 14/926803 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 18/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/80 (20130101) C04B 35/803 (20130101) C04B 2235/614 (20130101) C04B 2235/616 (20130101) C04B 2235/6028 (20130101) C04B 2237/38 (20130101) C04B 2237/62 (20130101) C04B 2237/84 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/22 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/20 (20130101) F01D 5/282 (20130101) Original (OR) Class F01D 5/284 (20130101) F01D 9/041 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/314 (20130101) F05D 2300/6033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273888 | Sellnau et al. |
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APPLICANT(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
ASSIGNEE(S) | DELPHI TECHNOLOGIES IP LIMITED (, Barbados) |
INVENTOR(S) | Mark C. Sellnau (Bloomfield Hills, Michigan); Wayne R. Moore (Goodrich, Michigan); James F. Sinnamon (Birmingham, Michigan) |
ABSTRACT | A GDCI engine recirculates exhaust gases to a combustion chamber using desired early injection parameters for a steady state engine operation from a controller. An engine control system detects a load increase relative to the steady state engine operation, and insufficient recirculated exhaust gases to the combustion chamber are delivered in response to the detected load increase as a result of transport delays. A last fuel injection into the combustion chamber during an engine cycle with multiple fuel injections is delayed as compared to the steady state engine operation. Combustion phasing within the combustion chamber is retarded in response to the delayed injection. |
FILED | Monday, February 15, 2016 |
APPL NO | 15/043739 |
ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Controlling Combustion Engines F02D 35/028 (20130101) Original (OR) Class F02D 41/005 (20130101) F02D 41/10 (20130101) F02D 41/0072 (20130101) F02D 41/402 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 26/06 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273940 | Pan et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Di Pan (Schenectady, New York); Liwei Hao (Schenectady, New York); Lijun He (Schenectady, New York); Stefan Grubic (Hermosa Beach, California) |
ABSTRACT | The present disclosure is directed to a system and method for detecting damage of a pitch bearing of a wind turbine. The pitch bearing is part of a pitch drive system having a plurality of pitch drive motors. The method includes measuring at least one electrical signal of the pitch drive system. The method also includes processing the electrical signal(s) of the pitch drive system and comparing the electrical signals of the pitch drive system with a baseline threshold. Thus, the method also includes determining whether damage is present in the pitch bearing based, at least in part, on the comparison, wherein the electrical signal(s) exceeding the baseline threshold is indicative of damage in the pitch bearing. |
FILED | Thursday, May 12, 2016 |
APPL NO | 15/152664 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Wind Motors F03D 7/0224 (20130101) F03D 17/00 (20160501) Original (OR) Class F03D 80/70 (20160501) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2260/80 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/721 (20130101) Y02E 10/723 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274292 | Lillo et al. |
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APPLICANT(S) | Thomas Martin Lillo (Idaho Falls, Idaho); Henry S. Chu (Idaho Falls, Idaho) |
ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
INVENTOR(S) | Thomas Martin Lillo (Idaho Falls, Idaho); Henry S. Chu (Idaho Falls, Idaho) |
ABSTRACT | One embodiment of the invention provides an alloy with a density greater than 10 g/cm3, the alloy comprising a single phase solution of tungsten, nickel, and iron. Also provided is a cone liner for use in shaped charges, the liner comprised of a tungsten, nickel, iron alloy having a single phase microstructure. Substantially no precipitates or second phases exist in the alloy. One embodiment of the invention further provides a method for producing a single phase alloy, the method comprising establishing a melt of iron and nickel; dissolving tungsten in the melt to form a solution; wherein the atomic percents of the nickel, tungsten and iron range from between approximately Ni-7%W-0%Fe, Ni-18%W-0%Fe, and Ni-8%W-24%Fe, wherein Ni is the remainder, maintaining the solution at a first temperature sufficient to create a homogeneous mixture; allowing the homogeneous mixture to solidify; and thermochemically treating the solidified mixture for a time to dissolve any second phases or microstructure within the mixture. |
FILED | Tuesday, February 17, 2015 |
APPL NO | 14/623987 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Alloys C22C 1/023 (20130101) C22C 19/03 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/10 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 1/028 (20130101) F42B 1/032 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274378 | Kane |
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APPLICANT(S) | Daniel James Kane (Santa Fe, New Mexico) |
ASSIGNEE(S) | Mesa Photonics, LLC (Santa Fe, New Mexico) |
INVENTOR(S) | Daniel James Kane (Santa Fe, New Mexico) |
ABSTRACT | A frequency resolved optical gating (FROG) system receives an ultrafast laser pulse as the “unknown wave” input to the system. The FROG system preferably generates a spectrogram (FROG trace) of the input pulse using a polarization gate, second harmonic generation or other FROG geometry. The system or method preferably analyzes the spectrogram using constrained outer products and principal component generalized projections to find characteristics of the unknown wave such as intensity and phase. Examples of constrained outer products include outer products that incorporate an external constraint such as spectral information or an internal constraint such as a relationship between the probe and gate components derived from the unknown wave. |
FILED | Thursday, April 26, 2018 |
APPL NO | 15/963285 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 9/02 (20130101) G01J 11/00 (20130101) Original (OR) Class G01J 2009/0261 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274421 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | Oregon State University (Corvallis, Oregon); U.S. Department of Energy (Washington, District of Columbia) |
ASSIGNEE(S) | Oregon State University (Corvallis, Oregon); U.S. Department of Energy (Washington, District of Columbia) |
INVENTOR(S) | Chih-hung Chang (Corvallis, Oregon); Ki-Joong Kim (Corvallis, Oregon); Alan X. Wang (Corvallis, Oregon); Yujing Zhang (Corvallis, Oregon); Xinyuan Chong (Corvallis, Oregon); Paul R. Ohodnicki (Allison Park, Pennsylvania) |
ABSTRACT | Disclosed herein are embodiments of sensor devices comprising a sensing component able to determine the presence of, detect, and/or quantify detectable species in a variety of environments and applications. The sensing components disclosed herein can comprise MOF materials, plasmonic nanomaterials, redox-active molecules, a metal, or any combinations thereof. In some exemplary embodiments, optical properties of the plasmonic nanomaterials and/or the redox-active molecules combined with MOF materials can be monitored directly to detect analyte species through their impact on external conditions surrounding the material or as a result of charge transfer to and from the plasmonic nanomaterial and/or the redox-active molecule as a result of interactions with the MOF material. |
FILED | Thursday, September 07, 2017 |
APPL NO | 15/698569 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Separation B01D 2253/204 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) B01J 20/226 (20130101) B01J 20/28007 (20130101) B01J 20/28097 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/359 (20130101) G01N 21/554 (20130101) G01N 21/3504 (20130101) Original (OR) Class G01N 21/7703 (20130101) G01N 2021/7709 (20130101) G01N 2021/7763 (20130101) G01N 2201/08 (20130101) Optical Elements, Systems, or Apparatus G02B 6/1226 (20130101) G02B 2006/12138 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274431 | Kauffman et al. |
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FUNDED BY |
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APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
INVENTOR(S) | Douglas Kauffman (Pittsburgh, Pennsylvania); Christopher Matranga (Pittsburgh, Pennsylvania); Paul R. Ohodnicki, Jr. (Allison Park, Pennsylvania); Xin Su (Wood-Ridge, New Jersey); Congjun Wang (Bethel Park, Pennsylvania) |
ABSTRACT | A method for evaluating the pH of an aqueous solution by utilizing the optical properties of a pH sensing material includes optically active nanoparticles fixed to a substrate. The optically active nanoparticles have a localized refractive index modulation over a pH range from 2.0 to 12.0 of at least 1% and, where the plurality of optically active nanoparticles have an average nanoparticle diameter of less than about 500 nanometers. The method includes contacting the pH sensing material with the aqueous solution, illuminating the pH sensing material, and monitoring an optical signal generated through comparison of incident light and exiting light to determine the optical transmission, absorption, reflection, and/or scattering of the pH sensitive material. The optical signal of the pH sensitive material varies in response to the pH of the aqueous solution, providing a means by which the pH and any changes in the pH may be analyzed. |
FILED | Thursday, April 14, 2016 |
APPL NO | 15/098714 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/77 (20130101) Original (OR) Class G01N 21/7703 (20130101) G01N 31/221 (20130101) G01N 33/84 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274462 | Restivo et al. |
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FUNDED BY |
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APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
INVENTOR(S) | Michael L. Restivo (Aiken, South Carolina); Kenneth J. Imrich (Grovetown, Georgia); Samuel D. Fink (Aiken, South Carolina); Mark R. Duignan (Evans, Georgia) |
ABSTRACT | A device for improving the accuracy and precision of measuring equipment changes due to corrosion, erosion, build-up of material, and combinations thereof. Increased control over the placement and removal of a coupon within the equipment is provided. Embodiments of the coupon provide multiple approaches for such measurements such as e.g., weight changes, thickness changes, inspection and analysis of the contacting surface of the coupon, and combination. Improved measurements with coupons using probes such as e.g., ultrasonic transducers is also described. |
FILED | Thursday, April 20, 2017 |
APPL NO | 15/492783 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 17/043 (20130101) G01N 17/046 (20130101) G01N 29/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274609 | Robinson et al. |
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FUNDED BY |
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APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho); Battelle Memorial Institute (Richland, Washington) |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho); Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Troy A. Robinson (Idaho Falls, Idaho); Martha R. Finck (Idaho Falls, Idaho); Matthew W. Cooper (Richland, Washington); James C. Hayes (Richland, Washington); Edward L. Reber (Idaho Falls, Idaho) |
ABSTRACT | A radioactive gas assay system comprises a scintillation cell production assembly, a detector assembly, a computer assembly, and a scintillation cell destruction assembly. The scintillation cell production assembly is configured to produce a scintillation cell comprising a glass scintillator shell containing a volume of radioactive gas. The detector assembly is configured to receive the scintillation cell and to detect photons emitted thereby. The computer assembly is configured to receive data from the detector assembly to automatically calculate an absolute activity of the volume of radioactive gas of the scintillation cell and radiation detection efficiencies of the detector assembly. The scintillation cell destruction assembly is configured to receive the scintillation cell and to rupture the substantially non-porous glass scintillator shell to release the volume of radioactive gas. A method of assaying a radioactive gas, and a scintillation cell are also described. |
FILED | Tuesday, May 09, 2017 |
APPL NO | 15/590359 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/766 (20130101) Measurement of Nuclear or X-radiation G01T 1/003 (20130101) Original (OR) Class G01T 1/20 (20130101) G01T 1/1645 (20130101) G01T 1/1663 (20130101) G01T 7/00 (20130101) G01T 7/02 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/02 (20130101) G21F 9/008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274807 | Geiger et al. |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois); Battelle Memorial Institute (Columbus, Ohio); The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Battelle Memorial Institute (Columbus, Ohio); The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Franz M. Geiger (Evanston, Wisconsin); Paul E. Ohno (Evanston, Illinois); Hong-fei Wang (Richland, Washington); Kenneth B. Eisenthal (New York City, New York) |
ABSTRACT | Methods of generating second harmonic generation (SHG) signals from interfaces formed with, or formed over, a noncentrosymmetric material, e.g., α-quartz, are provided. The methods make use of the noncentrosymmetric material as an internal phase reference for the determination of a variety of interfacial electrostatic parameters, including interfacial potential, interfacial charge density, and the sign of the interfacial charge (i.e., net positive or net negative). |
FILED | Thursday, December 07, 2017 |
APPL NO | 15/834250 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/84 (20130101) G01N 21/636 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/35 (20130101) G02F 1/355 (20130101) G02F 1/377 (20130101) G02F 1/3532 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274935 | Vernon |
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FUNDED BY |
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APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
INVENTOR(S) | Gregory John Vernon (Kansas City, Missouri) |
ABSTRACT | A system and method of creating a shape-conforming lattice structure for a part formed via additive manufacturing. The method includes receiving a computer model of the part and generating a finite element mesh. A lattice structure including a number of lattice cellular components may also be generated. Some of the mesh elements of the finite element mesh may be deformed so that the finite element mesh conforms to the overall shape of the part. The lattice structure may then be deformed so that the lattice structure has a cellular periodicity corresponding to the finite elements of the finite element mesh. In this way, the part retains the benefits of its overall shape and the benefits of lattice features without introducing structural weak points, directional stresses, and other structural deficiencies. |
FILED | Friday, January 15, 2016 |
APPL NO | 14/997238 |
ART UNIT | 2892 — Semiconductors/Memory |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/02 (20141201) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) Original (OR) Class G05B 2219/35134 (20130101) G05B 2219/49007 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/265 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10275551 | Rougier et al. |
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FUNDED BY |
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APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Esteban Rougier (Los Alamos, New Mexico); Earl Eugene Knight (Rio Rancho, New Mexico); Antonio Munjiza (London, United Kingdom) |
ABSTRACT | An integrated solver may be used for both a fluid phase and a solid phase. The integrated solver may use constitutive equations for the fluid phase and the solid phase, and calculate the stress in the fluid and solid using the same integration point. The integrated solver may also calculate other state variables using the same integration point. |
FILED | Thursday, July 24, 2014 |
APPL NO | 14/339760 |
ART UNIT | 2194 — Interprocess Communication and Software Development |
CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/26 (20130101) Electric Digital Data Processing G06F 17/5018 (20130101) Original (OR) Class G06F 2217/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276268 | Yacout et al. |
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APPLICANT(S) | A. M. Yacout (Naperville, Illinois); Michael J. Pellin (Naperville, Illinois); Michael Billone (Naperville, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | A. M. Yacout (Naperville, Illinois); Michael J. Pellin (Naperville, Illinois); Michael Billone (Naperville, Illinois) |
ABSTRACT | The invention provides a nuclear reactor cladding, wherein at least one layer of coating is deposited on the exterior surface of the cladding. A nuclear reactor cladding, wherein at least one layer of coating is deposited on the interior surface of the cladding. A method of coating a nuclear reactor cladding, with the steps of selecting the cladding and depositing at least one layer of a first coating on the cladding. |
FILED | Tuesday, September 03, 2013 |
APPL NO | 14/017096 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/405 (20130101) C23C 16/45529 (20130101) C23C 16/45555 (20130101) Nuclear Reactors G21C 3/07 (20130101) G21C 3/20 (20130101) Original (OR) Class G21C 21/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/40 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276271 | McClure et al. |
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FUNDED BY |
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APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | Triad National Security, LLC. (Los Alamos, New Mexico) |
INVENTOR(S) | Patrick Ray McClure (Los Alamos, New Mexico); David Duff Dixon (Elder, South Dakota); David Irvin Poston (Los Alamos, New Mexico); Lee Mason (North Royalton, Ohio); Marc Gibson (Medina, Ohio) |
ABSTRACT | Embodiments of the present invention pertain to a power system utilizing a uranium-based reactor for space missions. For example, the power system may include a reactor configured to generate thermal energy using a uranium core. A plurality of heat pipes may be configured to transfer thermal energy from the reactor core to a plurality of Stirling engines to generate electricity for a spacecraft. |
FILED | Wednesday, March 26, 2014 |
APPL NO | 14/770894 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Nuclear Reactors G21C 1/02 (20130101) G21C 1/32 (20130101) G21C 3/04 (20130101) G21C 3/08 (20130101) G21C 3/22 (20130101) G21C 3/40 (20130101) G21C 7/08 (20130101) G21C 11/06 (20130101) G21C 15/04 (20130101) G21C 15/257 (20130101) Original (OR) Class Nuclear Power Plant G21D 5/02 (20130101) Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 1/00 (20130101) G21H 3/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/34 (20130101) Y02E 30/39 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276286 | Lewicki et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | James Lewicki (Oakland, California); Marcus A. Worsley (Hayward, California) |
ABSTRACT | Disclosed here is a method for sensing temperature-dependent electrical switching response, comprising: exposing a polymer-carbon composite to a temperature change, wherein the polymer-carbon composite comprises (a) a semi-conductive or conductive carbon network intercalated with (b) a polymer matrix, wherein the carbon network comprises at least one covalently bonded carbon material, and wherein the polymer matrix comprises at least one polymer having a net electron withdrawing character and adapted to apply a gating effect on the conductive carbon; and detecting a change in electrical conductivity of the polymer-carbon composite of at least three orders of magnitude. Also disclosed is a smart switching device comprising the polymer-carbon composite and a switch triggerable by an increase or decrease in electrical conductivity of the polymer-carbon composite of at least three orders or magnitude. |
FILED | Wednesday, March 09, 2016 |
APPL NO | 15/065579 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/005 (20130101) C08J 2383/04 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) Resistors H01C 7/008 (20130101) Original (OR) Class Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 37/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276817 | Forrest et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | University of Southern California (Los Angeles, California); The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Quinn Burlingame (Ann Arbor, Michigan); Xin Xiao (Ann Arbor, Michigan); Kevin Bergemann (Ann Arbor, Michigan); Anurag Panda (Ann Arbor, Michigan); Jeramy D. Zimmerman (Golden, Colorado); Brian E. Lassiter (San Francisco, California); Mark E. Thompson (Anaheim, California); Andrew N. Bartynski (Los Angeles, California); Cong Trinh (San Jose, California) |
ABSTRACT | Disclosed herein are stable organic photosensitive devices including at least one exciton-blocking charge carrier filter. The filters comprise a mixture of at least one wide energy gap material having a sufficiently high glass transition temperature, e.g., higher than the temperature or temperature range at which the device typically operates, higher than a highest operating temperature of the device, higher than a threshold temperature value, etc. and at least one electron or hole conducting material. As described herein, the novel filters simultaneously block excitons and conduct the desired charge carrier (electrons or holes). |
FILED | Monday, July 20, 2015 |
APPL NO | 14/803643 |
ART UNIT | 2895 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/006 (20130101) H01L 51/0046 (20130101) H01L 51/0058 (20130101) H01L 51/0059 (20130101) H01L 51/0072 (20130101) H01L 51/0081 (20130101) H01L 51/4246 (20130101) H01L 51/4273 (20130101) Original (OR) Class H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276859 | Liu |
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FUNDED BY |
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APPLICANT(S) | Gao Liu (Piedmont, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Gao Liu (Piedmont, California) |
ABSTRACT | Embodiments of the present invention disclose a composition of matter comprising a silicon (Si) nanoparticle coated with a conductive polymer. Another embodiment discloses a method for preparing a composition of matter comprising a plurality of silicon (Si) nanoparticles coated with a conductive polymer comprising providing Si nanoparticles, providing a conductive polymer, preparing a Si nanoparticle, conductive polymer, and solvent slurry, spraying the slurry into a liquid medium that is a non-solvent of the conductive polymer, and precipitating the silicon (Si) nanoparticles coated with the conductive polymer. Another embodiment discloses an anode comprising a current collector, and a composition of matter comprising a silicon (Si) nanoparticle coated with a conductive polymer. |
FILED | Friday, July 07, 2017 |
APPL NO | 15/644364 |
ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/12 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) Original (OR) Class H01M 4/366 (20130101) H01M 4/386 (20130101) H01M 4/0416 (20130101) H01M 4/602 (20130101) H01M 4/623 (20130101) H01M 4/661 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) H01M 2220/20 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276860 | Yadav et al. |
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FUNDED BY |
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APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
INVENTOR(S) | Gautam G. Yadav (New York, New York); Joshua Gallaway (New York, New York); Michael Nyce (New York, New York); Sanjoy Banerjee (New York, New York) |
ABSTRACT | A secondary alkaline battery using manganese dioxide is described. The battery includes a mixed cathode material with birnessite-phase manganese dioxide or electrolytic manganese dioxide (EMD), a bismuth compound and a copper compound selected from the group consisting of elemental copper and a copper salt. In some embodiments, a conductive carbon and/or a binder may also be included. |
FILED | Thursday, March 23, 2017 |
APPL NO | 15/467240 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 45/02 (20130101) C01G 45/1228 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1653 (20130101) H01M 4/24 (20130101) H01M 4/30 (20130101) Original (OR) Class H01M 4/50 (20130101) H01M 4/364 (20130101) H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 4/626 (20130101) H01M 10/24 (20130101) H01M 10/28 (20130101) H01M 10/4235 (20130101) H01M 2004/028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276892 | Wachsman et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
ASSIGNEE(S) | University of Maryland (College Park, Maryland) |
INVENTOR(S) | Eric D. Wachsman (Fulton, Maryland); Gregory Thomas Hitz (Potomac, Maryland); Kang Taek Lee (Greenbelt, Maryland) |
ABSTRACT | Solid electrolytes compositions, methods of making the solid electrolytes, and methods of using the solid electrolytes in batteries and other electrochemical technologies are disclosed. The method of producing a solid electrolyte comprises (a) ball milling Na2CO3, SiO2, NH4H2PO4, a zirconium source, and a dopant to produce a ball milled powder; (b) calcining the ball milled powder to produce a calcined powder; and (c) sintering the calcined powder to produce a solid electrolyte. The zirconium source for the solid electrolyte may be ZrO2. The dopant for the solid electrolyte may be AI2O3, Fe2O3, Sb2O3, Yb2O3, or Dy2O3. |
FILED | Wednesday, September 25, 2013 |
APPL NO | 14/430453 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 25/45 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/05 (20130101) H01M 10/39 (20130101) H01M 10/054 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2008/1293 (20130101) H01M 2220/20 (20130101) H01M 2300/0068 (20130101) H01M 2300/0071 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276942 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Xiuling Li (Champaign, Illinois); Wen Huang (Champaign, Illinois); Paul J. Froeter (Urbana, Illinois) |
ABSTRACT | A wireless communication device includes an array of helical antennas on a substrate. Each helical antenna comprises a strain-relieved sheet with a conductive strip thereon, where the strain-relieved sheet and the conductive strip are in a rolled configuration about a longitudinal axis. The conductive strip is oriented at an angle α with respect to a rolling direction so as to comprise a helical configuration about the longitudinal axis with a non-zero helix angle β. The array exhibits a maximum gain of at least about 10 dB at a working frequency of at least about 0.1 THz. |
FILED | Wednesday, January 18, 2017 |
APPL NO | 15/408893 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 11/08 (20130101) Original (OR) Class H01Q 21/061 (20130101) H01Q 21/0087 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276946 | Benzel et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC. (Livermore, California); Dirac Solutions, Inc. (Pleasanton, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); Dirac Solutions, inc. (Pleasanton, California) |
INVENTOR(S) | David M. Benzel (Livermore, California); Richard E. Twogood (San Diego, California) |
ABSTRACT | A single Vivaldi antenna plate (half Vivaldi antenna) over a ground plane can be used to achieve a 50-ohm impedance, or two or more single plates over a ground plane to achieve other impedances. Unbalanced 50-ohm transmission lines, e.g., coaxial cables, can be used to directly feed the antenna. |
FILED | Friday, March 31, 2017 |
APPL NO | 15/476686 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/48 (20130101) H01Q 13/085 (20130101) H01Q 15/14 (20130101) H01Q 21/08 (20130101) H01Q 21/064 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277041 | Zane et al. |
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FUNDED BY |
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APPLICANT(S) | Utah State University (Logan, Utah); FORD GLOBAL TECHNOLOGIES, LLC (Dearborn, Michigan); ALLIANCE FOR SUSTAINABLE ENERGY, LLC (Golden, Colorado); THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY (Denver, Colorado) |
ASSIGNEE(S) | UTAH STATE UNIVERSITY (Logan, Utah); ALLIANCE FOR SUSTAINABLE ENERGY, LLC (Golden, Colorado); FORD GLOBAL TECHNOLOGIES, LLC (Dearborn, Michigan); THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
INVENTOR(S) | Regan A. Zane (North Logan, Utah); Michael Evzelman (Logan, Utah); Daniel Costinett (Knoxville, Tennessee); Dragan Maksimovic (Boulder, Colorado); Richard Dyche Anderson (Plymouth, Michigan); Kandler Smith (Golden, Colorado); Michael Scott Trimboli (Colorado Springs, Colorado); Gregory L. Plett (Colorado Springs, Colorado) |
ABSTRACT | An apparatus includes a battery state module that determines a battery state of each of a plurality of battery cells forming a battery unit. A battery state includes a health of the battery cell. A battery state of a battery cell differs from a battery state of other battery cells of the battery unit. Each battery cell is connected to a shared bus through a bypass converter that provides power from the battery cell to the shared bus. A charge/discharge modification module determines, based on battery state, an amount to vary a charging characteristic for each battery cell compared to a reference charging characteristic. Each charging characteristic varies as a function of a reference state. A charge/discharge module adjusts charging/discharging of a battery cell of the battery unit based on the charging characteristic of the battery cell. |
FILED | Friday, July 29, 2016 |
APPL NO | 15/224123 |
ART UNIT | 2859 — Printing/Measuring and Testing |
CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 1/102 (20130101) H02J 7/0016 (20130101) Original (OR) Class H02J 7/0021 (20130101) H02J 7/0052 (20130101) H02J 7/0068 (20130101) H02J 2007/0059 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/33507 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277147 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Xudong Wang (Middleton, Wisconsin); Zhiyong Cai (Madison, Wisconsin); Chunhua Yao (Madison, Wisconsin); Alberto Hernandez (Baltimore, Maryland); Yanhao Yu (Madison, Wisconsin) |
ABSTRACT | Triboelectric nanogenerators that operate in a vertical contact separation mode and methods for fabricating the triboelectric generators are provided. Also provided are methods for using the triboelectric nanogenerators to harvest mechanical energy and convert it into electric energy. In the TENGs, one or both of the triboelectrically active layers comprises a cellulose that has been chemically treated to alter its electron affinity. |
FILED | Thursday, June 09, 2016 |
APPL NO | 15/178285 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/02 (20130101) B29C 65/00 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2001/08 (20130101) B29K 2995/0026 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/34 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/30 (20130101) C23C 16/45525 (20130101) Electric Machines Not Otherwise Provided for H02N 1/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10278276 | Elizondo-Decanini |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Juan M. Elizondo-Decanini (Albuquerque, New Mexico) |
ABSTRACT | Short pulse neutron generators are described herein. In a general embodiment, the short pulse neutron generator includes a Blumlein structure. The Blumlein structure includes a first conductive plate, a second conductive plate, a third conductive plate, at least one of an inductor or a resistor, a switch, and a dielectric material. The first conductive plate is positioned relative to the second conductive plate such that a gap separates these plates. A vacuum chamber is positioned in the gap, and an ion source is positioned to emit ions in the vacuum chamber. The third conductive plate is electrically grounded, and the switch is operable to electrically connect and disconnect the second conductive plate and the third conductive plate. The at least one of the resistor or the inductor is coupled to the first conductive plate and the second conductive plate. |
FILED | Wednesday, June 22, 2016 |
APPL NO | 15/190035 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/12 (20130101) H05H 3/06 (20130101) Original (OR) Class H05H 5/03 (20130101) H05H 5/047 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 10271728 | Melodia et al. |
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FUNDED BY |
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APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
INVENTOR(S) | Tommaso Melodia (Newton, Massachusetts); Giuseppe Enrico Santagati (Cambridge, Massachusetts) |
ABSTRACT | An ultrasonic communication system and method provide a networking framework for wearable devices based on ultrasonic communications. The ultrasonic communication system and method incorporate a set of physical, data link, network and application layer functionalities that can flexibly adapt to application and system requirements to efficiently distribute information between ultrasonic wearable devices. |
FILED | Tuesday, January 26, 2016 |
APPL NO | 15/538930 |
ART UNIT | 2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0015 (20130101) Original (OR) Class A61B 5/0024 (20130101) A61B 5/0026 (20130101) A61B 5/0028 (20130101) A61B 5/0205 (20130101) A61B 5/02438 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) Transmission H04B 11/00 (20130101) Wireless Communication Networks H04W 84/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10271780 | Van Duyne et al. |
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FUNDED BY |
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APPLICANT(S) | Richard P. Van Duyne (Wilmette, Illinois); Matthew R. Glucksberg (Chicago, Illinois); Joseph T. Walsh, Jr. (Evanston, Illinois); Jonathan M. Yuen (Chicago, Illinois); Nilam C. Shah (Chicago, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Richard P. Van Duyne (Wilmette, Illinois); Matthew R. Glucksberg (Chicago, Illinois); Joseph T. Walsh, Jr. (Evanston, Illinois); Jonathan M. Yuen (Chicago, Illinois); Nilam C. Shah (Chicago, Illinois) |
ABSTRACT | The present invention provides systems and methods employing a surface enhanced Raman biosensor and sensing devices for collecting spatially offset Raman spectra from the biosensor. In certain embodiments, the present invention provides systems and methods for quantifying the concentration of an analyte in a subject, and/or identifying the presence or absence of an analyte in a subject, from a plurality of spatially offset Raman spectra generated from a surface enhanced Raman biosensor implanted in a subject. |
FILED | Wednesday, November 23, 2011 |
APPL NO | 13/303815 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1455 (20130101) A61B 5/1459 (20130101) Original (OR) Class A61B 5/14532 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272126 | Duncan et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
INVENTOR(S) | Bradley Duncan (Andover, Massachusetts); Xiaoning Li (Hillsboro, Oregon); Vincent M. Rotello (Amherst, Massachusetts) |
ABSTRACT | A stabilized microcapsule includes a liquid hydrophobic core including an essential oil and an aromatic monoaldehyde, and a shell encapsulating the core, the shell including a plurality of amino-functionalized inorganic nanoparticles. Also disclosed is a dispersion including a plurality of the stabilized microcapsules. The microcapsules and dispersions can be particularly useful for treating a bacterial biofilm. |
FILED | Thursday, July 21, 2016 |
APPL NO | 15/216134 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/04 (20130101) A01N 25/04 (20130101) A01N 25/28 (20130101) A01N 25/28 (20130101) A01N 27/00 (20130101) A01N 27/00 (20130101) A01N 27/00 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 37/40 (20130101) A01N 37/40 (20130101) A01N 37/40 (20130101) A01N 49/00 (20130101) A01N 49/00 (20130101) A01N 49/00 (20130101) A01N 65/00 (20130101) A01N 65/00 (20130101) A01N 65/00 (20130101) A01N 65/10 (20130101) A01N 65/10 (20130101) A01N 65/10 (20130101) A01N 65/22 (20130101) A01N 65/22 (20130101) A01N 65/22 (20130101) A01N 65/24 (20130101) A01N 65/24 (20130101) A01N 65/24 (20130101) A01N 65/28 (20130101) A01N 65/28 (20130101) A01N 65/28 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/501 (20130101) A61K 31/12 (20130101) A61K 36/534 (20130101) Original (OR) Class A61K 47/52 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/0082 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) Y02A 50/478 (20180101) Y02A 50/479 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272180 | Jiang et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Shaoyi Jiang (Redmond, Washington); Tao Bai (Seattle, Washington); Harihara Subramanian Sundaram (Seattle, Washington); Andrew William Sinclair (Seattle, Washington); Jean-René Ella-Menye (Seattle, Washington); Priyesh Jain (Seattle, Washington) |
ABSTRACT | Functionalized zwitterionic and mixed charge polymers and copolymers, methods for making the polymers and copolymers, hydrogels prepared from the functionalized zwitterionic and mixed charge polymers and copolymers, methods for making and using the hydrogels, and zwitterionic and mixed charge polymers and copolymers for administration for therapeutic agents. |
FILED | Wednesday, September 09, 2015 |
APPL NO | 15/509607 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 47/58 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/22 (20130101) A61L 15/24 (20130101) A61L 15/42 (20130101) A61L 24/0031 (20130101) A61L 24/046 (20130101) A61L 27/16 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/3804 (20130101) A61L 31/06 (20130101) A61L 31/10 (20130101) A61L 31/145 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/36 (20130101) C08F 2220/365 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/021 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 2533/30 (20130101) C12N 2539/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272184 | Schmidt et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Christine E. Schmidt (Gainesville, Florida); Scott A. Zawko (Austin, Texas); Sarah M. Mayes (Austin, Texas) |
ABSTRACT | A biocompatible membrane comprised of alginate and hyaluronate. The membrane may be used to prevent unwanted scarring after surgery. The tissue adherence and the rate of bioresorption of the membrane may be modified through an external stimulus comprising a sequestering agent and a viscosity modifier. |
FILED | Wednesday, May 17, 2017 |
APPL NO | 15/597541 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0077 (20130101) A61F 2002/009 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/16 (20130101) A61L 31/041 (20130101) A61L 31/041 (20130101) A61L 31/041 (20130101) A61L 31/041 (20130101) A61L 31/145 (20130101) Original (OR) Class A61L 31/148 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 5/18 (20130101) C08J 2305/04 (20130101) C08J 2405/08 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 5/08 (20130101) C08L 89/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272414 | Hernandez-Maldonado et al. |
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FUNDED BY |
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APPLICANT(S) | Arturo J Hernandez-Maldonado (Mayaguez, Puerto Rico); Milton E Rivera-Ramos (Ponce, Puerto Rico); Ana G Arevalo-Hidalgo (Mayaguez, Puerto Rico) |
ASSIGNEE(S) | University of Puerto Rico (San Juan, Puerto Rico) |
INVENTOR(S) | Arturo J Hernandez-Maldonado (Mayaguez, Puerto Rico); Milton E Rivera-Ramos (Ponce, Puerto Rico); Ana G Arevalo-Hidalgo (Mayaguez, Puerto Rico) |
ABSTRACT | Na+-SAPO-34 sorbents were ion-exchanged with several individual metal cations for CO2 absorption at different temperatures (273-348 K) and pressures (<1 atm). In general, the overall adsorption performance of the exchanged materials increased as follows: Ce3+<Ti3+<Mg2+<Ca2+<Ag+<Na+<Sr2+. The strontium exchanged materials excelled at low-pressure ranges, exhibiting very sharp isotherms slopes at all temperatures. The Sr2+ species were responsible for the surface strong interaction and the cations were occupying exposed sites (SII′) in the materials Chabazite cages. All the sorbent materials exhibited higher affinity for CO2 over the other gases tested (i.e., CH4, H2, N2 and O2) due to strong ion-quadrupole interactions. Sr2+-SAPO-34 sorbents are by far the best option for CO2 removal from CH4 mixtures, especially at low concentrations. |
FILED | Wednesday, August 24, 2016 |
APPL NO | 15/245565 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Separation B01D 53/02 (20130101) B01D 2253/116 (20130101) B01D 2253/304 (20130101) B01D 2253/311 (20130101) B01D 2257/504 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/186 (20130101) Original (OR) Class B01J 20/3078 (20130101) B01J 20/3085 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272424 | Bae et al. |
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FUNDED BY |
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APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
INVENTOR(S) | Chulsung Bae (Cohoes, New York); Angela Dee Mohanty (Clifton Park, New York) |
ABSTRACT | Embodiments of the invention relate generally to anion exchange membranes and, more particularly, to anion exchange membranes comprising a styrene block copolymer and methods for their manufacture. In one embodiment, the invention provides a polymer according to formula IV, wherein x and y are mo 1 %, QA is or each of R1 and R2 is, independently, a linear alkyl chain or a cyclic alkyl chain, and Z is selected from a group consisting of: a linear alkyl chain, a cyclic alkyl chain, and an alkylene ether chain. |
FILED | Wednesday, July 22, 2015 |
APPL NO | 15/326538 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/14 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/00 (20130101) C08F 8/04 (20130101) C08F 8/18 (20130101) C08F 8/24 (20130101) C08F 8/42 (20130101) C08F 8/44 (20130101) C08F 8/44 (20130101) C08F 8/44 (20130101) C08F 8/44 (20130101) C08F 297/04 (20130101) C08F 297/04 (20130101) C08F 297/04 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 13/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/083 (20130101) H01M 8/103 (20130101) H01M 8/1023 (20130101) H01M 2008/1095 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/56 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273256 | Butlin et al. |
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FUNDED BY |
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APPLICANT(S) | LUMIPHORE, INC. (Berkeley, California) |
ASSIGNEE(S) | LUMIPHORE, INC. (Berkeley, California) |
INVENTOR(S) | Nathaniel G. Butlin (Pacifica, California); Darren Magda (San Leandro, California); Jide Xu (Richmond, California) |
ABSTRACT | The invention relates to chemical compounds and complexes that can be used in therapeutic and diagnostic applications. |
FILED | Friday, June 22, 2018 |
APPL NO | 16/015911 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Heterocyclic Compounds C07D 259/00 (20130101) C07D 471/22 (20130101) C07D 487/08 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/005 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273314 | Van Dyk et al. |
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FUNDED BY |
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APPLICANT(S) | Antony K. Van Dyk (Blue Bell, Pennsylvania); Susan J. Fitzwater (Ambler, Pennsylvania); Sven Fleischmann (Ludwigshafen, Germany); Virgil Percec (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | ROHM AND HAAS COMPANY (Philadelphia, Pennsylvania); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
INVENTOR(S) | Antony K. Van Dyk (Blue Bell, Pennsylvania); Susan J. Fitzwater (Ambler, Pennsylvania); Sven Fleischmann (Ludwigshafen, Germany); Virgil Percec (Philadelphia, Pennsylvania) |
ABSTRACT | SET-LRP polymerization of acrylic monomers under acidic conditions is described. The source of the acidity may be the solvent (e.g., an acetic acid-containing solvent) or in the monomer content (e.g., acrylic acid or methacrylic acid, optionally in combination with other monomers such as methyl methacrylate). |
FILED | Friday, July 22, 2011 |
APPL NO | 13/811820 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/06 (20130101) Original (OR) Class C08F 4/10 (20130101) C08F 4/40 (20130101) C08F 20/14 (20130101) C08F 120/14 (20130101) C08F 220/06 (20130101) C08F 220/14 (20130101) C08F 220/14 (20130101) C08F 2438/00 (20130101) C08F 2438/01 (20130101) C08F 2438/02 (20130101) C08F 2438/03 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273333 | Maynard |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Heather D. Maynard (Los Angeles, California) |
ABSTRACT | Structures and methods of making biodegradable trehalose co-polymers are disclosed. Specifically, biodegradable trehalose co-polymers consist of the general structure R5—[R1R2C—CR3R4]n-[DG]m—R6, wherein R1-R4 are independently selected from hydrogen or a side chain comprising at least one carbon atom, and wherein at least one of R1-R4 is a side chain comprising -L-trehalose, wherein L is a linker molecule that links trehalose to the monomer through at least one of the trehalose hydroxyl groups (—OH), wherein DG is a biodegradable group, and wherein R5 and R6 are end groups. |
FILED | Thursday, December 29, 2016 |
APPL NO | 15/394483 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/193 (20130101) A61K 47/30 (20130101) A61K 47/34 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 3/04 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0006 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2220/285 (20130101) C08F 2438/03 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/08 (20130101) C08G 63/78 (20130101) C08G 63/91 (20130101) C08G 63/688 (20130101) C08G 63/912 (20130101) Original (OR) Class C08G 63/6852 (20130101) C08G 63/6882 (20130101) C08G 2230/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273339 | Lavigne et al. |
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FUNDED BY |
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APPLICANT(S) | John J. Lavigne (Columbia, South Carolina); R. William Tilford (Kingsport, Tennessee) |
ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
INVENTOR(S) | John J. Lavigne (Columbia, South Carolina); R. William Tilford (Kingsport, Tennessee) |
ABSTRACT | Porous networks are described linked by boronates. Also described are processes for producing the porous networks. The porous networks are formed by reacting a polyboronic acid with itself or with a polydiol, a polydiamine, or a polyamino alcohol. The resulting boronate linkage is covalently bonded. The characteristics and properties of the resulting porous material can be varied and altered by changing the reactants and by incorporating functional groups into the reactants. Of particular advantage, the porous materials can be formed at or near atmospheric pressure and at low temperature in the presence of one or more solvents. |
FILED | Monday, September 08, 2014 |
APPL NO | 14/479414 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/00 (20130101) Original (OR) Class C08J 2485/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273407 | Collins et al. |
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FUNDED BY |
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APPLICANT(S) | INTELLIGENT MATERIAL SOLUTIONS, INC. (Princeton, New Jersey); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | INTELLIGENT MATERIAL SOLUTIONS, INC. (Princeton, New Jersey); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
INVENTOR(S) | Joshua E. Collins (Philadelphia, Pennsylvania); Howard Y. Bell (Princeton, New Jersey); Xingchen Ye (Philadelphia, Pennsylvania); Christopher Bruce Murray (Montgomery County, Pennsylvania) |
ABSTRACT | Monodisperse particles having: a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology are disclosed. Due to their uniform size and shape, the monodisperse particles self assemble into superlattices. The particles may be luminescent particles such as down-converting phosphor particles and up-converting phosphors. The monodisperse particles of the invention have a rare earth-containing lattice which in one embodiment may be an yttrium-containing lattice or in another may be a lanthanide-containing lattice. The monodisperse particles may have different optical properties based on their composition, their size, and/or their morphology (or shape). Also disclosed is a combination of at least two types of monodisperse particles, where each type is a plurality of monodisperse particles having a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology; and where the types of monodisperse particles differ from one another by composition, by size, or by morphology. In a preferred embodiment, the types of monodisperse particles have the same composition but different morphologies. Methods of making and methods of using the monodisperse particles are disclosed. |
FILED | Thursday, August 30, 2018 |
APPL NO | 16/117453 |
ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 15/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/0031 (20130101) C01F 17/0043 (20130101) C01F 17/0062 (20130101) C01F 17/0087 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/54 (20130101) C01P 2002/72 (20130101) C01P 2002/84 (20130101) C01P 2004/04 (20130101) C01P 2004/10 (20130101) C01P 2004/11 (20130101) C01P 2004/16 (20130101) C01P 2004/20 (20130101) C01P 2004/32 (20130101) C01P 2004/40 (20130101) C01P 2004/42 (20130101) C01P 2004/52 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7773 (20130101) C09K 11/7791 (20130101) Original (OR) Class Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/08 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2933 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273464 | Noel et al. |
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FUNDED BY |
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APPLICANT(S) | The Salk Institute for Biological Studies (La Jolla, California) |
ASSIGNEE(S) | The Salk Institute Of Biological Studies (San Diego, California) |
INVENTOR(S) | Joseph P. Noel (San Diego, California); Nikki M. Dellas (La Jolla, California) |
ABSTRACT | Provided herein are methods and compositions relating to the synthesis of isoprenoid diphosphates using a mutated isopentenyl phosphate kinase. |
FILED | Thursday, April 30, 2015 |
APPL NO | 14/701389 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1217 (20130101) C12N 9/1229 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 9/00 (20130101) Enzymes C12Y 207/04026 (20150701) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274384 | Dunne et al. |
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FUNDED BY |
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APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Lucy E. Dunne (Minneapolis, Minnesota); Guido Gioberto (Minneapolis, Minnesota) |
ABSTRACT | A stitched sensor including a plurality of threads stitched to a textile in a stitch geometry is described. The plurality of threads includes a conductive thread, and the stitch geometry is configured such that an electrical property of the stitched sensor changes based on at least one of stretching, relaxation, or bending of the textile. Methods for forming a stitched sensor are also described. |
FILED | Monday, February 05, 2018 |
APPL NO | 15/888562 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Sewing D05B 93/00 (20130101) D05B 97/08 (20130101) D05B 97/12 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/18 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/205 (20130101) G01L 1/2287 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274421 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | Oregon State University (Corvallis, Oregon); U.S. Department of Energy (Washington, District of Columbia) |
ASSIGNEE(S) | Oregon State University (Corvallis, Oregon); U.S. Department of Energy (Washington, District of Columbia) |
INVENTOR(S) | Chih-hung Chang (Corvallis, Oregon); Ki-Joong Kim (Corvallis, Oregon); Alan X. Wang (Corvallis, Oregon); Yujing Zhang (Corvallis, Oregon); Xinyuan Chong (Corvallis, Oregon); Paul R. Ohodnicki (Allison Park, Pennsylvania) |
ABSTRACT | Disclosed herein are embodiments of sensor devices comprising a sensing component able to determine the presence of, detect, and/or quantify detectable species in a variety of environments and applications. The sensing components disclosed herein can comprise MOF materials, plasmonic nanomaterials, redox-active molecules, a metal, or any combinations thereof. In some exemplary embodiments, optical properties of the plasmonic nanomaterials and/or the redox-active molecules combined with MOF materials can be monitored directly to detect analyte species through their impact on external conditions surrounding the material or as a result of charge transfer to and from the plasmonic nanomaterial and/or the redox-active molecule as a result of interactions with the MOF material. |
FILED | Thursday, September 07, 2017 |
APPL NO | 15/698569 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Separation B01D 2253/204 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) B01J 20/226 (20130101) B01J 20/28007 (20130101) B01J 20/28097 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/359 (20130101) G01N 21/554 (20130101) G01N 21/3504 (20130101) Original (OR) Class G01N 21/7703 (20130101) G01N 2021/7709 (20130101) G01N 2021/7763 (20130101) G01N 2201/08 (20130101) Optical Elements, Systems, or Apparatus G02B 6/1226 (20130101) G02B 2006/12138 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274492 | Almasri et al. |
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FUNDED BY |
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APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
ASSIGNEE(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
INVENTOR(S) | Mahmoud Almasri (Columbia, Missouri); Shibajyoti Ghosh Dastider (Columbia, Missouri); Shuping Zhang (Columbia, Missouri); Majed El Dweik (Jefferson City, Missouri); Nuh Sadi Yuksek (Columbia, Missouri); Ibrahem Jasim (Columbia, Missouri); Jiayu Liu (Columbia, Missouri) |
ABSTRACT | Disclosed herein are example embodiments of a transformative sensor apparatus that is capable of detecting and quantifying the presence of a substance of interest such as a specified bacteria within a sample via changes in impedance exhibited by a detection electrode array. In an example embodiment, sensitivity is improved by including a focusing electrode array in a rampdown channel to focus a concentration of the substance of interest into a detection region. The focusing electrodes include an opposing pair of electrodes in a rampdown orientation. The focusing electrode may also include tilted thin film finger electrodes extending from the rampdown electrodes. In another example embodiment, trapping electrodes are positioned to trap a concentration of the substance of interest onto the detection electrode array. |
FILED | Friday, April 08, 2016 |
APPL NO | 15/094045 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2300/087 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0887 (20130101) B01L 2400/0424 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/06 (20130101) G01N 33/5438 (20130101) G01N 33/56916 (20130101) Original (OR) Class G01N 2333/245 (20130101) G01N 2333/255 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274525 | Savvides et al. |
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FUNDED BY |
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APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Andreas Savvides (Hamden, Connecticut); Deokwoo Jung (Seoul, South Korea) |
ABSTRACT | Systems and methods are provided for estimating power breakdowns for a set of one or more appliances inside a building by exploiting a small number of power meters and data indicative of binary power states of individual appliances of such set. In one aspect, a breakdown estimation problem is solved within a tree configuration, and utilizing a single power meter and data indicative of binary power states of a plurality of appliances. Based at least in part on such solution, an estimation quality metric is derived. In another aspect, such metric can be exploited in a methodology for optimally placing additional power meters to increase the estimation certainty for individual appliances to a desired or intended level. Estimated power breakdown and energy breakdown—individually or collectively referred to as consumption breakdown—rely on measurements and numerical simulations, and can be evaluated in exemplary electrical network utilizing binary sensors. |
FILED | Tuesday, November 29, 2016 |
APPL NO | 15/363750 |
ART UNIT | 2865 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 21/1333 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/06 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/14 (20130101) H02J 13/0017 (20130101) H02J 2003/143 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 90/2607 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/527 (20130101) Y04S 40/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274592 | Guo |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Dongning Guo (Chicago, Illinois) |
ABSTRACT | A node in a wireless network includes a memory, transceiver, and processor operatively coupled to one another. The memory stores a signature of the node. The transceiver is configured to transmit, during an initial frame, the signature to one or more neighboring nodes, and receive, during the initial frame, a first signal that includes one or more signatures of the one or more neighboring nodes. The transceiver is also configured to transmit, during a repetition frame, a scrambled waveform of the first signal received during the initial frame, and receive, during the repetition frame, a second signal that includes a retransmission of signals received by the one or more neighboring nodes during the initial frame. The processor is configured to determine a distance from the node to each of the one or more neighboring nodes based at least in part on the first signal and the second signal. |
FILED | Wednesday, April 12, 2017 |
APPL NO | 15/485326 |
ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0289 (20130101) G01S 11/06 (20130101) Original (OR) Class G01S 13/767 (20130101) Transmission H04B 17/27 (20150115) H04B 17/318 (20150115) H04B 17/364 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274731 | Maimone |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Andrew Stephen Maimone (Durham, North Carolina) |
ABSTRACT | According to one aspect, the subject matter described herein includes a near-eye optical see-through display. The display includes a backlight layer including a plurality of point light sources. The display further includes a spatial light modulator (SLM) layer for modulating light from the point light sources. The spatial light modulator is located in the optical path between the point light sources and a user's eye. The spatial light modulator layer includes pixels that are controllable to modulate light from the point light sources such that the light that impacts the user's eye has a desired intensity and color to display a synthetic image. At least a portion of the backlight layer and the spatial light modulator layer are optically transparent to allow a user to view a real scene through the spatial light modulator layer and the backlight layer such that the synthetic image appears to be overlaid on a view of the real scene. Each pixel in the spatial light modulator layer modulates only a portion of the light emanating from the point light sources such that the synthetic image appears to be in focus to the user's eye. |
FILED | Friday, December 19, 2014 |
APPL NO | 15/105903 |
ART UNIT | 2625 — Selective Visual Display Systems |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/0008 (20130101) G02B 6/0043 (20130101) G02B 26/04 (20130101) G02B 27/0093 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 27/0179 (20130101) G02B 2027/0123 (20130101) G02B 2027/0132 (20130101) G02B 2027/0174 (20130101) G02B 2027/0178 (20130101) G02B 2027/0187 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/002 (20130101) G09G 3/3406 (20130101) G09G 3/3611 (20130101) Pictorial Communication, e.g Television H04N 9/3182 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274807 | Geiger et al. |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois); Battelle Memorial Institute (Columbus, Ohio); The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Battelle Memorial Institute (Columbus, Ohio); The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Franz M. Geiger (Evanston, Wisconsin); Paul E. Ohno (Evanston, Illinois); Hong-fei Wang (Richland, Washington); Kenneth B. Eisenthal (New York City, New York) |
ABSTRACT | Methods of generating second harmonic generation (SHG) signals from interfaces formed with, or formed over, a noncentrosymmetric material, e.g., α-quartz, are provided. The methods make use of the noncentrosymmetric material as an internal phase reference for the determination of a variety of interfacial electrostatic parameters, including interfacial potential, interfacial charge density, and the sign of the interfacial charge (i.e., net positive or net negative). |
FILED | Thursday, December 07, 2017 |
APPL NO | 15/834250 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/84 (20130101) G01N 21/636 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/35 (20130101) G02F 1/355 (20130101) G02F 1/377 (20130101) G02F 1/3532 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274987 | Puggelli et al. |
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FUNDED BY |
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APPLICANT(S) | Lion Semiconductor Inc. (San Francisco, California) |
ASSIGNEE(S) | Lion Semiconductor Inc. (San Francisco, California) |
INVENTOR(S) | Alberto Alessandro Angelo Puggelli (Oakland, California); Thomas Li (Mountain View, California); Wonyoung Kim (Berkeley, California); John Crossley (Oakland, California); Hanh-Phuc Le (Richmond, California) |
ABSTRACT | The present disclosure shows a reconfigurable Dickson Star SC regulator that can support multiple conversion ratios by reconfiguring between various modes. The reconfigurable Dickson Star SC regulator is designed to reduce the number of redundant capacitors by reusing capacitors and switches across multiple modes of operation (across multiple conversion ratios). The present disclosure also shows a hybrid (e.g., two-stage) voltage regulator. |
FILED | Friday, April 14, 2017 |
APPL NO | 15/487659 |
ART UNIT | 2859 — Printing/Measuring and Testing |
CURRENT CPC | Systems for Regulating Electric or Magnetic Variables G05F 5/00 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0052 (20130101) H02J 7/0065 (20130101) H02J 2007/0062 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/07 (20130101) H02M 3/1582 (20130101) H02M 2001/007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10275164 | Luo et al. |
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FUNDED BY |
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APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
INVENTOR(S) | Hao Luo (Lincoln, Nebraska); Hong Jiang (Lincoln, Nebraska); Lei Tian (Lincoln, Nebraska) |
ABSTRACT | In one implementation, a computer-implemented method can include receiving, at a driver running on a mobile computing device with a local power source, a command from an application for an allocation of volatile memory; allocating, by the driver, memory from a pool of volatile memory for the application; storing data in the allocated memory; detecting, by the driver, that a particular situation currently exists on the mobile computing device that will cause the data to be lost; and performing, by the driver, an operation with regard to the memory and the data that will cause the data to be preserved following a conclusion of the particular situation. |
FILED | Friday, May 27, 2016 |
APPL NO | 15/167378 |
ART UNIT | 2131 — Printing/Measuring and Testing |
CURRENT CPC | Electric Digital Data Processing G06F 3/0619 (20130101) Original (OR) Class G06F 3/0631 (20130101) G06F 3/0647 (20130101) G06F 3/0653 (20130101) G06F 3/0673 (20130101) G06F 12/023 (20130101) G06F 12/0246 (20130101) G06F 17/30 (20130101) G06F 2212/161 (20130101) G06F 2212/171 (20130101) G06F 2212/214 (20130101) G06F 2212/222 (20130101) G06F 2212/1032 (20130101) G06F 2212/7203 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276370 | Filler et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Michael A. Filler (Atlanta, Georgia); Sven Holger Behrens (Atlanta, Georgia); Laurens Victor Breedveld (Atlanta, Georgia) |
ABSTRACT | A method for forming nanostructures including introducing a hollow shell into a reactor. The hollow shell has catalyst nanoparticles exposed on its interior surface. The method also includes introducing a precursor into the reactor to grow nanostructures from the interior surface of the hollow shell from the catalyst nanoparticles. |
FILED | Tuesday, December 29, 2015 |
APPL NO | 15/540622 |
ART UNIT | 2816 — Semiconductors/Memory |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/045 (20130101) C23C 16/442 (20130101) C23C 16/4417 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02532 (20130101) H01L 21/02543 (20130101) H01L 21/02546 (20130101) H01L 21/02576 (20130101) H01L 21/02579 (20130101) H01L 21/02603 (20130101) H01L 21/02606 (20130101) H01L 21/02645 (20130101) H01L 21/02653 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276942 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Xiuling Li (Champaign, Illinois); Wen Huang (Champaign, Illinois); Paul J. Froeter (Urbana, Illinois) |
ABSTRACT | A wireless communication device includes an array of helical antennas on a substrate. Each helical antenna comprises a strain-relieved sheet with a conductive strip thereon, where the strain-relieved sheet and the conductive strip are in a rolled configuration about a longitudinal axis. The conductive strip is oriented at an angle α with respect to a rolling direction so as to comprise a helical configuration about the longitudinal axis with a non-zero helix angle β. The array exhibits a maximum gain of at least about 10 dB at a working frequency of at least about 0.1 THz. |
FILED | Wednesday, January 18, 2017 |
APPL NO | 15/408893 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 11/08 (20130101) Original (OR) Class H01Q 21/061 (20130101) H01Q 21/0087 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277189 | Morgan |
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FUNDED BY |
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APPLICANT(S) | Associated Universities, Inc. (Washington, District of Columbia) |
ASSIGNEE(S) | Associated Universities, Inc. (Washington, District of Columbia) |
INVENTOR(S) | Matthew Alexander Morgan (Earlysville, Virginia) |
ABSTRACT | Reflectionless transmission line filters, as well as a method for designing such filters is disclosed. These filters preferably function by absorbing the stop-band portion of the spectrum rather than reflecting it back to the source, which has significant advantages in many different applications. The insertion of additional transmission line sections that change the phase response of the circuit without altering the amplitude response preferably allows follow-up transmission line identities to be applied in order to arrive at a more easily manufacturable filter topology. This facilitates their application over a higher frequency range the solely lumped-element circuits. |
FILED | Wednesday, March 14, 2018 |
APPL NO | 15/920674 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/00 (20130101) Original (OR) Class H03H 7/06 (20130101) H03H 7/0123 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277240 | Ojeda |
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FUNDED BY |
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APPLICANT(S) | Associated Universities, Inc. (Washington, District of Columbia) |
ASSIGNEE(S) | Associated Universities, Inc. (Washington, District of Columbia) |
INVENTOR(S) | Omar Artemi Yeste Ojeda (Gordonsville, Virginia) |
ABSTRACT | Methods and systems for generating a digital representation of the amplitude and phase of a bandpass signal are disclosed. The methods comprise filtering the bandpass signal with a bandpass filter, generating the real and imaginary parts of the complex analytic signal with a quadrature hybrid, determining the amplitude of the complex analytic signal by adding an even power-law transform of the real and imaginary parts of the complex analytic signal, and determining the phase of the complex analytic signal by comparing the real and imaginary parts of the complex analytic signal to zero and comparing an even power-law transform of the real and imaginary parts of the complex analytic signal to each other. Analog to digital converters and methods of converting complex analytic signals to digital signals are also disclosed. |
FILED | Thursday, December 13, 2018 |
APPL NO | 16/218845 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Demodulation or Transference of Modulation From One Carrier to Another H03D 3/007 (20130101) H03D 2200/008 (20130101) Coding; Decoding; Code Conversion in General H03M 1/1245 (20130101) Original (OR) Class Transmission H04B 1/0042 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277305 | Shafer et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents acting for and on behalf of Northern Arizona University (Flagstaff, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents acting for and on behalf of Northern Arizona University (Flagstaff, Arizona) |
INVENTOR(S) | Michael W. Shafer (Flagstaff, Arizona); Paul G. Flikkema (Flagstaff, Arizona); Joseph Davidson (Flagstaff, Arizona) |
ABSTRACT | Implementations of UAV wildlife monitoring system may include a ground control station wirelessly coupled to a UAV which may include a flight controller, a first radio, a second radio, a first antenna, a second antenna, a very high frequency (VHF) radio receiver, and a computer, all operatively coupled together. The monitoring system may also include a VHF tag configured to be coupled to an animal, wherein when the VHF tag is coupled to the animal, the VHF radio receiver receives a VHF radio signal from the VHF tag using the first antenna, wherein the computer process the VHF radio signal to create the location data from the VHF radio signal, processes the location data, and sends the location data to the second radio, wherein the second radio transmits the location data into a telecommunications channel, and wherein the ground control station receives the location data from the telecommunications channel. |
FILED | Monday, April 30, 2018 |
APPL NO | 15/966371 |
ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 11/006 (20130101) A01K 29/005 (20130101) Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 31/002 (20130101) Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/12 (20130101) B64C 2201/146 (20130101) B64C 2201/203 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0252 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0038 (20130101) G05D 1/0044 (20130101) Transmission H04B 1/10 (20130101) H04B 1/0343 (20130101) H04B 7/18504 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277382 | Eltawil et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Ahmed Mohamed Eltawil (Oakland, California); Elsayed A. Ahmed (Oakland, California) |
ABSTRACT | Embodiments of transceivers with one or more reconfigurable antennas are described. In one embodiment, a reconfigurable antenna transceiver includes a transmit chain, a receive chain, and a reconfigurable antenna having a plurality of reconfigurable modes. The transceiver may also include an antenna controller configured to set a mode of the reconfigurable antenna. According to other aspects, the transceiver may also include a signal processor configured to transmit a set of training symbols during a training interval. The antenna controller may be further configured to select a respective mode of the reconfigurable antenna for each training symbol in the set of training symbols. Additionally, the antenna controller may be configured to calculate a received Signal-of-Interest to Interferer Ratio (SIR) for each training symbol of the set of training symbols. In this context, a system utilizing a reconfigurable antenna may achieve significant rate improvement compared to half-duplex systems. |
FILED | Thursday, May 04, 2017 |
APPL NO | 15/587047 |
ART UNIT | 2464 — Multiplex and VoIP |
CURRENT CPC | Transmission H04B 1/525 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/14 (20130101) H04L 5/1453 (20130101) H04L 5/1461 (20130101) Original (OR) Class Wireless Communication Networks H04W 24/10 (20130101) H04W 88/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 10272414 | Hernandez-Maldonado et al. |
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FUNDED BY |
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APPLICANT(S) | Arturo J Hernandez-Maldonado (Mayaguez, Puerto Rico); Milton E Rivera-Ramos (Ponce, Puerto Rico); Ana G Arevalo-Hidalgo (Mayaguez, Puerto Rico) |
ASSIGNEE(S) | University of Puerto Rico (San Juan, Puerto Rico) |
INVENTOR(S) | Arturo J Hernandez-Maldonado (Mayaguez, Puerto Rico); Milton E Rivera-Ramos (Ponce, Puerto Rico); Ana G Arevalo-Hidalgo (Mayaguez, Puerto Rico) |
ABSTRACT | Na+-SAPO-34 sorbents were ion-exchanged with several individual metal cations for CO2 absorption at different temperatures (273-348 K) and pressures (<1 atm). In general, the overall adsorption performance of the exchanged materials increased as follows: Ce3+<Ti3+<Mg2+<Ca2+<Ag+<Na+<Sr2+. The strontium exchanged materials excelled at low-pressure ranges, exhibiting very sharp isotherms slopes at all temperatures. The Sr2+ species were responsible for the surface strong interaction and the cations were occupying exposed sites (SII′) in the materials Chabazite cages. All the sorbent materials exhibited higher affinity for CO2 over the other gases tested (i.e., CH4, H2, N2 and O2) due to strong ion-quadrupole interactions. Sr2+-SAPO-34 sorbents are by far the best option for CO2 removal from CH4 mixtures, especially at low concentrations. |
FILED | Wednesday, August 24, 2016 |
APPL NO | 15/245565 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Separation B01D 53/02 (20130101) B01D 2253/116 (20130101) B01D 2253/304 (20130101) B01D 2253/311 (20130101) B01D 2257/504 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/186 (20130101) Original (OR) Class B01J 20/3078 (20130101) B01J 20/3085 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272987 | Turner et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
INVENTOR(S) | Travis L. Turner (Yorktown, Virginia); Reggie T. Kidd (Hampton, Virginia); David P Lockard (Hampton, Virginia); Mehdi R. Khorrami (Norfolk, Virginia); Craig L. Streett (Virginia Beach, Virginia); Douglas Leo Weber (Hayes, Virginia) |
ABSTRACT | A slat cove filler is utilized to reduce airframe noise resulting from deployment of a leading edge slat of an aircraft wing. The slat cove filler is preferably made of a super elastic shape memory alloy, and the slat cove filler shifts between stowed and deployed shapes as the slat is deployed. The slat cove filler may be configured such that a separate powered actuator is not required to change the shape of the slat cove filler from its deployed shape to its stowed shape and vice-versa. The outer contour of the slat cove filler preferably follows a profile designed to maintain accelerating flow in the gap between the slat cove filler and wing leading edge to provide for noise reduction. |
FILED | Monday, January 25, 2016 |
APPL NO | 15/005338 |
ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeroplanes; Helicopters B64C 3/48 (20130101) Original (OR) Class B64C 9/22 (20130101) B64C 9/24 (20130101) B64C 2230/14 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/14 (20130101) Y02T 50/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273024 | Youngquist et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Adminstrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as Represented by the Adminstrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | Robert C. Youngquist (Cocoa, Florida); Mark A. Nurge (Oviedo, Florida) |
ABSTRACT | A multi-layer radiation reflector/emitter includes first and second materials. The first material is transparent to radiation in a wavelength spectrum ranging from approximately 0.2 microns to at last 6 microns. The first material is a self-supporting arrangement of randomized particles having an average dimension in a range of approximately 0.2 microns to approximately 0.4 microns and defining a fill factor of approximately 0.1 to approximately 0.5. The second material reflects radiation having a wavelength greater than approximately 2 microns. |
FILED | Tuesday, September 27, 2016 |
APPL NO | 15/277446 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/58 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273403 | Luther et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Abhishek Swarnkar (Jharkhand, India); The Regents of the University of Colorado, a body corporate (Denver, Colorado); University of Washington (Seattle, Washington) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); University of Washington (Seattle, Washington); Regents of the University of Colorado, a body corporate (Denver, Colorado) |
INVENTOR(S) | Joseph Matthew Luther (Boulder, Colorado); Abhishek Swarnkar (Jharkhand, India); Ashley Rae Marshall (Golden, Colorado); Erin Mariko Sanehira (Lakewood, Colorado) |
ABSTRACT | The present disclosure relates to a composition that includes a particle and a surface species, where the particle has a characteristic length between greater than zero nm and 100 nm inclusively, and the surface species is associated with a surface of the particle such that the particle maintains a crystalline form when the composition is at a temperature between −180° C. and 150° C. |
FILED | Wednesday, May 31, 2017 |
APPL NO | 15/609401 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/22 (20130101) C09D 5/24 (20130101) C09D 7/67 (20180101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) Original (OR) Class C09K 11/665 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/20 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02167 (20130101) H01L 31/035218 (20130101) H01L 33/04 (20130101) H01L 33/44 (20130101) H01L 51/426 (20130101) H01L 51/448 (20130101) H01L 51/5237 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/95 (20130101) Y10S 977/774 (20130101) Y10S 977/825 (20130101) Y10S 977/896 (20130101) Y10S 977/948 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273944 | Huang et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Wensheng Huang (Cleveland, Ohio); John Yim (Cleveland, Ohio) |
ABSTRACT | A propellant distributor or anode includes a plenum chamber and a plurality of outlets. The at least one plenum chamber is configured to receive a flow of propellant from an inlet, and the plurality of outlets are configured to distribute the flow of propellant into an inner channel wall and an outer channel wall of a discharge channel. |
FILED | Tuesday, November 04, 2014 |
APPL NO | 14/532066 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/405 (20130101) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0012 (20130101) Original (OR) Class F03H 1/0075 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/54 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274116 | Merheb et al. |
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FUNDED BY |
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APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Federico Merheb (Rockledge, Florida); Orlando Torres (Rockledge, Florida); Nicholas W. Newell (Orlando, Florida); Donald C. Barnes (Huntsville, Alabama) |
ABSTRACT | Systems and methods according to one or more embodiments are provided for providing a durable and thermally insulated duct network. A duct network may be provided by coupling two or more foam ducts to each other. In one example, a system includes a plurality of foam ducts and a plurality of foam bellows configured to couple the foam ducts to each other. The foam bellows include one or more bellow folds to allow an expansion and contraction of the foam ducts. A plurality of structural fastening systems couple the duct network to a structure of a vessel. The structural fastening systems allow for an axial movement of the duct network as the foam ducts expand and contract. Additional systems and methods are also provided. |
FILED | Friday, January 29, 2016 |
APPL NO | 15/011171 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/00 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 3/01 (20130101) F16L 3/10 (20130101) F16L 3/18 (20130101) F16L 9/12 (20130101) F16L 9/21 (20130101) F16L 27/11 (20130101) Original (OR) Class F16L 51/025 (20130101) F16L 59/143 (20130101) Pipe-line Systems; Pipe-lines F17D 1/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274644 | Yao et al. |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Youwei Yao (Evanston, Illinois); Melville Paul Ulmer (Evanston, Illinois); Jian Cao (Wilmette, Illinois); Xiaoli Wang (Evanston, Illinois) |
ABSTRACT | A deposition system for forming a stress distributed coating layer is provided which comprises a deposition apparatus comprising a source from which a coating material emanates, the source configured to restrict a flux of the coating material towards a backside of an optical substrate; a holder configured to hold the optical substrate; a drive system configured to provide relative translation of the source and the optical substrate; and a bias voltage power supply operably coupled to the source and the optical substrate and configured to apply a bias voltage between the source and the backside of the optical substrate. A device is operably coupled to the deposition apparatus, the device comprising a processor; and a computer-readable medium operably coupled to the processor, the computer-readable medium having computer-readable instructions stored thereon that, when executed by the processor, cause the deposition apparatus to deposit the coating material onto the backside of the optical substrate and to adjust the bias voltage between the source and the backside of the optical substrate during the deposition of the coating material as a function of relative position of the source and the optical substrate to provide a stress distributed coating layer on the backside of the optical substrate. |
FILED | Monday, November 27, 2017 |
APPL NO | 15/822386 |
ART UNIT | 1781 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/35 (20130101) C23C 14/042 (20130101) C23C 14/185 (20130101) C23C 14/345 (20130101) Optical Elements, Systems, or Apparatus G02B 1/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10275548 | Kodali et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of the NASA (Washington, District of Columbia) |
INVENTOR(S) | Anuradha Kodali (Sunnyvale, California); Peter I. Robinson (Palo Alto, California) |
ABSTRACT | Interactive diagnostic modeling evaluator (i-DME) for repairing a diagnostic matrix of a system. The diagnostic modeling evaluator cause steps to be performed comprising: evaluating a first diagnostic performance of a diagnostic unit using supervised data that includes one or more instances of a fault of a system; proposing a repair to the diagnostic unit based on the evaluated diagnostic performance; evaluating a second diagnostic performance of the diagnostic unit having the proposed repair; and upon determining that the second diagnostic performance meets a performance metric criterion, repairing the diagnostic unit according to the proposed repair. |
FILED | Wednesday, October 07, 2015 |
APPL NO | 14/877584 |
ART UNIT | 2127 — AI & Simulation/Modeling |
CURRENT CPC | Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10276926 | Cwik et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Thomas A. Cwik (Pasadena, California); Nacer E. Chahat (Pasadena, California); Jonathan Sauder (Pasadena, California); Manan Arya (Pasadena, California); Ellen Thiel (Pasadena, California) |
ABSTRACT | A deployable reflectarray antenna stowable in a 6U CubeSat volume is deployed through tape deployers and quartz cables. The telescoping waveguide is attached to the horn with a threaded insert. The reflectarray antenna has, at 37.75 GHz, a directivity of 48.5 dBi, a gain of 47.8 dBi, and an aperture efficiency of 42%. Hinges with a ball-end screw enable precise control of deployment angle of adjacent panels in the reflectarray antenna. |
FILED | Thursday, December 21, 2017 |
APPL NO | 15/850861 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/08 (20130101) H01Q 1/10 (20130101) H01Q 1/288 (20130101) Original (OR) Class H01Q 3/06 (20130101) H01Q 3/46 (20130101) H01Q 13/02 (20130101) H01Q 15/145 (20130101) H01Q 15/161 (20130101) H01Q 19/08 (20130101) H01Q 19/18 (20130101) H01Q 19/104 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277346 | Downey et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | James M. Downey (North Ridgeville, Ohio); Bryan L. Schoenholz (Brunswick, Ohio); Joseph A. Downey (Grafton, Ohio) |
ABSTRACT | A high efficiency secondary signal combiner may include a frequency division multiplexer that is configured to receive two or more signals and produce a combined signal. The combined signal may include the two or more signals, and each of the two or more signals may be in different Nyquist zones. The combiner may also include a wideband analog-to-digital converter (ADC) that is configured to frequency shift the combined signal by sub-sampling the two or more signals to produce a sub-sampled signal in a Nyquist zone that is different from the Nyquist zones of the two or more signals. |
FILED | Friday, July 08, 2016 |
APPL NO | 15/205575 |
ART UNIT | 2631 — Digital Communications |
CURRENT CPC | Multiplex Communication H04J 1/08 (20130101) Original (OR) Class Wireless Communication Networks H04W 72/0453 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277520 | Johnson |
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FUNDED BY |
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APPLICANT(S) | Southwest Research Institute (San Antonio, Texas) |
ASSIGNEE(S) | SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas) |
INVENTOR(S) | Mark A. Johnson (Spicewood, Texas) |
ABSTRACT | A packet transfer buffer for use in a computer system having multiple source and destination interfaces, as well as packet handling software. The buffer has a source packet FIFO and destination packet FIFO, each with an associated packet length counter. The packet handling software obtains packet lengths from the source packet counter, and provides the packet length to the destination packet counter. The buffer has hardware circuitry that handles transfer of data from the source packet FIFO to the destination packet FIFO without the need for word-by-word reads and writes by the packet handling software. |
FILED | Tuesday, January 17, 2017 |
APPL NO | 15/407848 |
ART UNIT | 2462 — Multiplex and VoIP |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/6245 (20130101) Original (OR) Class H04L 49/901 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 10271744 | Narayan et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia); Topera, Inc. (Menlo Park, California) |
INVENTOR(S) | Sanjiv Narayan (La Jolla, California); Carey Robert Briggs (La Jolla, California); Ruchir Sehra (Scottsdale, Arizona) |
ABSTRACT | In a system and method for identifying a driver of a source associated with a heart rhythm disorder, data are accessed from a plurality of sensors representing biological activity in the heart. A first region and a second region of the heart, which comprise the source of the heart rhythm disorder, are identified. If the first region of the heart has repeating centrifugal activation and controls the second region of the heart for at least a predetermined number of beats, the first region is identified as controlling the source of the heart rhythm disorder. |
FILED | Friday, April 22, 2016 |
APPL NO | 15/136268 |
ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0002 (20130101) A61B 5/0006 (20130101) A61B 5/044 (20130101) A61B 5/046 (20130101) A61B 5/0422 (20130101) A61B 5/0452 (20130101) A61B 5/02405 (20130101) Original (OR) Class A61B 5/02444 (20130101) A61B 5/04012 (20130101) A61B 5/6852 (20130101) A61B 2560/0475 (20130101) A61B 2562/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10271786 | Narayan et al. |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia); Topera, Inc. (Menlo Park, California) |
INVENTOR(S) | Sanjiv Narayan (La Jolla, California); Carey Robert Briggs (La Jolla, California) |
ABSTRACT | Reconstruction of cardiac information associated with a heart rhythm disorder includes accessing a plurality of neighboring cardiac signals and eliminating far-field activations from the neighboring cardiac signals using one or more divergence criteria that define local activations, where the divergence criteria is associated with divergence among the plurality of neighboring cardiac signals. The local activations in the plurality of neighboring cardiac signals may be used to construct a clinical representation of the heart rhythm disorder. |
FILED | Thursday, July 07, 2016 |
APPL NO | 15/204455 |
ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0422 (20130101) A61B 5/0452 (20130101) A61B 5/02405 (20130101) A61B 5/04012 (20130101) A61B 5/4836 (20130101) Original (OR) Class A61B 5/7203 (20130101) A61B 5/7239 (20130101) A61B 5/7278 (20130101) A61B 2562/046 (20130101) A61B 2562/0209 (20130101) Electric Digital Data Processing G06F 19/3418 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272009 | Schem |
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APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
ASSIGNEE(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
INVENTOR(S) | Clifford Schem (Pleasanton, California) |
ABSTRACT | A casket transport and lowering device system is presented. The system includes a transportable frame with extendable rails configured to rotate and extend out over a gravesite. The extendable rails may also include an end rail and one or more extendable feet. The transportable frame may also be protected inside an exterior housing. The system also includes a carriage that rolls along the extendable rails into a position directly over the top of the gravesite. The carriage supports a lowering device upon which the casket rests. When the carriage is positioned over the gravesite, the lowering device is also positioned to lower the casket into the grave. |
FILED | Friday, November 17, 2017 |
APPL NO | 15/816978 |
ART UNIT | 3618 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 19/00 (20130101) Original (OR) Class A61G 21/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272097 | Ren et al. |
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FUNDED BY |
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APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia); DURECT CORPORATION (Cupertino, California) |
ASSIGNEE(S) | Virginia Commonwealth University (Richmond, Virginia); Durect Corporation (Cupertino, California) |
INVENTOR(S) | Shunlin Ren (Richmond, Virginia); Felix Theeuwes (Los Altos Hills, California); James E. Brown (Los Gatos, California); WeiQi Lin (Emerald Hills, California) |
ABSTRACT | Methods of preventing and/or treating ischemia, organ dysfunction and/or organ failure, including multiple organ dysfunction syndrome (MODS), and necrosis and apoptosis associated with organ dysfunction/failure, are provided. For instance, the methods involve contacting organ(s) with an oxygenated cholesterol sulfate (OCS), e.g. 5-cholesten-3,25-diol, 3-sulfate (25HC3S). The organ(s) may be in vivo (e.g. in a patient that is treated with the OCS) or ex vivo (e.g. an organ that has been harvested from a donor and is to be transplanted). |
FILED | Tuesday, December 23, 2014 |
APPL NO | 15/106883 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/568 (20130101) A61K 31/575 (20130101) Original (OR) Class A61K 35/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10272163 | Laterza et al. |
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APPLICANT(S) | HAPLOMICS, INC. (Atlanta, Georgia); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America Represented by the Department of Veterans Affairs (Washington, District of Columbia); Haplomics, Inc. (Manhatten Beach, California) |
INVENTOR(S) | Vincent Laterza (Atlanta, Georgia); Tommy E. Howard (Redondo Beach, California) |
ABSTRACT | Methods of treating hemophilia A in a subject with an F8 gene mutation, wherein the F8 gene is repaired and the resultant repaired gene, upon expression, confers improved coagulation functionality to the encoded FVIII protein of the subject compared to the non-repaired F8 gene. The invention also includes methods of inducing immune tolerance to a FVIII replacement product ((r)FVIII) in a subject having a FVIII deficiency, wherein the F8 gene mutation is repaired and the repaired gene, upon expression, provides for the induction of immune tolerance to an administered replacement FVIII protein product. The invention also includes isolated nucleic acids, vectors, recombinant viruses, cells, and pharmaceutical compositions to repair the F8 gene. |
FILED | Friday, December 06, 2013 |
APPL NO | 14/649910 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/0066 (20130101) Original (OR) Class Peptides C07K 14/755 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/90 (20130101) C12N 2830/42 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273549 | Helgason et al. |
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FUNDED BY |
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APPLICANT(S) | VitroLabs Inc (London, United Kingdom); King's College London (London, United Kingdom) |
ASSIGNEE(S) | VITROLABS INC. (London, United Kingdom); KING'S COLLEGE LONDON (London, United Kingdom) |
INVENTOR(S) | Ingvar Helgason (London, United Kingdom); Dusko Ilic (London, United Kingdom) |
ABSTRACT | Disclosed herein are synthetic leathers, artificial epidermal layers, artificial dermal layers, layered structures, products produced therefrom and methods of producing the same. |
FILED | Thursday, April 20, 2017 |
APPL NO | 15/493083 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0625 (20130101) C12N 5/0629 (20130101) C12N 5/0698 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2502/13 (20130101) C12N 2502/091 (20130101) C12N 2502/094 (20130101) C12N 2506/45 (20130101) C12N 2533/30 (20130101) C12N 2533/54 (20130101) Chemical Treatment of Hides, Skins or Leather, e.g Tanning, Impregnating, Finishing; Apparatus Therefor; Compositions for Tanning C14C 3/02 (20130101) Original (OR) Class C14C 13/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 10273547 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Jinbo Wang (Berwyn Heights, Maryland); Tyler Dang (Riverside, California); Georgios Vidalakis (Riverside, California) |
ABSTRACT | The present invention provides methods and compositions for detecting multiple citrus pathogens using a multiplex branched DNA signal amplification reaction. |
FILED | Friday, July 18, 2014 |
APPL NO | 14/905741 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/701 (20130101) C12Q 1/6895 (20130101) C12Q 2600/13 (20130101) C12Q 2600/16 (20130101) C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274492 | Almasri et al. |
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FUNDED BY |
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APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
ASSIGNEE(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
INVENTOR(S) | Mahmoud Almasri (Columbia, Missouri); Shibajyoti Ghosh Dastider (Columbia, Missouri); Shuping Zhang (Columbia, Missouri); Majed El Dweik (Jefferson City, Missouri); Nuh Sadi Yuksek (Columbia, Missouri); Ibrahem Jasim (Columbia, Missouri); Jiayu Liu (Columbia, Missouri) |
ABSTRACT | Disclosed herein are example embodiments of a transformative sensor apparatus that is capable of detecting and quantifying the presence of a substance of interest such as a specified bacteria within a sample via changes in impedance exhibited by a detection electrode array. In an example embodiment, sensitivity is improved by including a focusing electrode array in a rampdown channel to focus a concentration of the substance of interest into a detection region. The focusing electrodes include an opposing pair of electrodes in a rampdown orientation. The focusing electrode may also include tilted thin film finger electrodes extending from the rampdown electrodes. In another example embodiment, trapping electrodes are positioned to trap a concentration of the substance of interest onto the detection electrode array. |
FILED | Friday, April 08, 2016 |
APPL NO | 15/094045 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2300/087 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0887 (20130101) B01L 2400/0424 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/06 (20130101) G01N 33/5438 (20130101) G01N 33/56916 (20130101) Original (OR) Class G01N 2333/245 (20130101) G01N 2333/255 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277147 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Xudong Wang (Middleton, Wisconsin); Zhiyong Cai (Madison, Wisconsin); Chunhua Yao (Madison, Wisconsin); Alberto Hernandez (Baltimore, Maryland); Yanhao Yu (Madison, Wisconsin) |
ABSTRACT | Triboelectric nanogenerators that operate in a vertical contact separation mode and methods for fabricating the triboelectric generators are provided. Also provided are methods for using the triboelectric nanogenerators to harvest mechanical energy and convert it into electric energy. In the TENGs, one or both of the triboelectrically active layers comprises a cellulose that has been chemically treated to alter its electron affinity. |
FILED | Thursday, June 09, 2016 |
APPL NO | 15/178285 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/02 (20130101) B29C 65/00 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2001/08 (20130101) B29K 2995/0026 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/34 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/30 (20130101) C23C 16/45525 (20130101) Electric Machines Not Otherwise Provided for H02N 1/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP30448 | Finn |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by The Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Chad E. Finn (Corvallis, Oregon) |
ABSTRACT | A new and distinct blackberry cultivar that originated from seed produced from a cross between the female blackberry plant ‘ORUS 1393-1’ (unpatented) and the male blackberry plant ‘Triple Crown’ (unpatented). This new blackberry is unique in that it contains all three commercial blackberry types (trailing, erect, and semi-erect) in its pedigree as either a parent or a grandparent. This new blackberry cultivar can be distinguished by being early ripening for a semi-erect blackberry, by its medium-sized, firm berries with tough skin and very good flavor, by its medium to high yields borne on a vigorous plant with a semi-erect type growth habit and by its completely thornless canes. |
FILED | Tuesday, June 20, 2017 |
APPL NO | 15/731503 |
ART UNIT | 1661 — Plants |
CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/7499 (20180501) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 10273256 | Butlin et al. |
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FUNDED BY |
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APPLICANT(S) | LUMIPHORE, INC. (Berkeley, California) |
ASSIGNEE(S) | LUMIPHORE, INC. (Berkeley, California) |
INVENTOR(S) | Nathaniel G. Butlin (Pacifica, California); Darren Magda (San Leandro, California); Jide Xu (Richmond, California) |
ABSTRACT | The invention relates to chemical compounds and complexes that can be used in therapeutic and diagnostic applications. |
FILED | Friday, June 22, 2018 |
APPL NO | 16/015911 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Heterocyclic Compounds C07D 259/00 (20130101) C07D 471/22 (20130101) C07D 487/08 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/005 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10274484 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | Mediomics LLC (St. Louis, Missouri) |
ASSIGNEE(S) | Mediomics LLC (St. Louis, Missouri) |
INVENTOR(S) | Yie-Hwa Chang (St. Louis, Missouri); Ling Tian (St. Louis, Missouri); Sally Tricomi (St. Louis, Missouri) |
ABSTRACT | The invention generally provides molecular biosensors with modular epitope binding constructs. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules. |
FILED | Friday, September 11, 2015 |
APPL NO | 14/851788 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277324 | Morton et al. |
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FUNDED BY |
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APPLICANT(S) | Morton Photonics (West Friendship, Maryland) |
ASSIGNEE(S) | Morton Photonics (West Friendship, Maryland) |
INVENTOR(S) | Paul A. Morton (West Friendship, Maryland); Jacob Khurgin (Pikesville, Maryland) |
ABSTRACT | High-performance ultra-wideband Phased Array Sensors (PAS) are disclosed, which have unique capabilities, enabled through photonic integrated circuits and novel optical architectures. Unique capabilities for a Receive PAS are provided by wafer scale photonic integration including heterogeneous integration of III-V materials and ultra-low-loss silicon nitride waveguides, combining key component technologies into complex PIC devices. Novel aspects include optical multiplexing combining wavelength division multiplexing and/or a novel extension to array photodetectors providing the capability to combine many RF photonic signals with very low loss. The architecture also includes optical down-conversion, as well as digital signal processing to improve the linearity of the system. Simultaneous multi-channel beamforming is achieved through optical power splitting of optical signals to create multiple exact replicas of the signals that are then processed independently. |
FILED | Wednesday, October 10, 2018 |
APPL NO | 16/156087 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/2676 (20130101) Transmission H04B 10/50 (20130101) H04B 10/516 (20130101) H04B 10/25759 (20130101) Original (OR) Class H04B 2210/006 (20130101) Selecting H04Q 5/00 (20130101) H04Q 11/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277438 | Terry |
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FUNDED BY |
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APPLICANT(S) | John David Terry (Annandale, Virginia) |
ASSIGNEE(S) | |
INVENTOR(S) | John David Terry (Annandale, Virginia) |
ABSTRACT | The present invention teaches method and apparatus to transform a featureless, unpredictable, and non-repeatable chaos waveform into digital chaos waveforms that maintain featureless characteristics to serve as a for wireless communications protocol, whereby unintended observers cannot detect or disrupt yet imprint a small measure of predictability and repeatability to aid intend observers in recovering embedded information. |
FILED | Tuesday, July 26, 2011 |
APPL NO | 13/190478 |
ART UNIT | 2631 — Digital Communications |
CURRENT CPC | Multiplex Communication H04J 13/10 (20130101) H04J 13/0018 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/001 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
US 10272179 | Martinson et al. |
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FUNDED BY |
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APPLICANT(S) | ViaCyte, Inc. (San Diego, California) |
ASSIGNEE(S) | ViaCyte, Inc. (San Diego, California) |
INVENTOR(S) | Laura Martinson (San Diego, California); Chad Green (San Diego, California); Evert Kroon (San Diego, California); Emmanuel Edward Baetge (San Diego, California) |
ABSTRACT | The present invention relates to a perforated semi-permeable device comprising, human pancreatic endocrine cells or human PDX1-positive pancreatic endoderm cells contained within a semi-permeable membrane comprising a synthetic material, wherein the synthetic material is polysulfone (PSF), nano-fiber mats, polyimide, tetrafluoroethylene/polytetrafluoroethylene (PTFE), expanded polytetrafluoroethylene (ePTFE), polyacrylonitrile, polyethersulfone, acrylic resin, cellulose acetate, cellulose nitrate, polyamide, or hydroxylpropyl methyl cellulose (HPMC), a cell encapsulation chamber, and at least one seal that is within the cell encapsulation chamber. |
FILED | Wednesday, August 16, 2017 |
APPL NO | 15/679002 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/022 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/39 (20130101) A61K 38/28 (20130101) A61K 2035/126 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/14 (20130101) A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/3804 (20130101) Original (OR) Class A61L 2300/62 (20130101) A61L 2300/64 (20130101) A61L 2300/252 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/00 (20130101) A61M 31/00 (20130101) A61M 31/002 (20130101) A61M 2202/07 (20130101) A61M 2205/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0676 (20130101) C12N 5/0678 (20130101) C12N 2501/16 (20130101) C12N 2501/19 (20130101) C12N 2501/41 (20130101) C12N 2501/115 (20130101) C12N 2501/117 (20130101) C12N 2501/119 (20130101) C12N 2501/385 (20130101) C12N 2501/415 (20130101) C12N 2506/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273339 | Lavigne et al. |
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FUNDED BY |
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APPLICANT(S) | John J. Lavigne (Columbia, South Carolina); R. William Tilford (Kingsport, Tennessee) |
ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
INVENTOR(S) | John J. Lavigne (Columbia, South Carolina); R. William Tilford (Kingsport, Tennessee) |
ABSTRACT | Porous networks are described linked by boronates. Also described are processes for producing the porous networks. The porous networks are formed by reacting a polyboronic acid with itself or with a polydiol, a polydiamine, or a polyamino alcohol. The resulting boronate linkage is covalently bonded. The characteristics and properties of the resulting porous material can be varied and altered by changing the reactants and by incorporating functional groups into the reactants. Of particular advantage, the porous materials can be formed at or near atmospheric pressure and at low temperature in the presence of one or more solvents. |
FILED | Monday, September 08, 2014 |
APPL NO | 14/479414 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/00 (20130101) Original (OR) Class C08J 2485/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10273549 | Helgason et al. |
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FUNDED BY |
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APPLICANT(S) | VitroLabs Inc (London, United Kingdom); King's College London (London, United Kingdom) |
ASSIGNEE(S) | VITROLABS INC. (London, United Kingdom); KING'S COLLEGE LONDON (London, United Kingdom) |
INVENTOR(S) | Ingvar Helgason (London, United Kingdom); Dusko Ilic (London, United Kingdom) |
ABSTRACT | Disclosed herein are synthetic leathers, artificial epidermal layers, artificial dermal layers, layered structures, products produced therefrom and methods of producing the same. |
FILED | Thursday, April 20, 2017 |
APPL NO | 15/493083 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0625 (20130101) C12N 5/0629 (20130101) C12N 5/0698 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2502/13 (20130101) C12N 2502/091 (20130101) C12N 2502/094 (20130101) C12N 2506/45 (20130101) C12N 2533/30 (20130101) C12N 2533/54 (20130101) Chemical Treatment of Hides, Skins or Leather, e.g Tanning, Impregnating, Finishing; Apparatus Therefor; Compositions for Tanning C14C 3/02 (20130101) Original (OR) Class C14C 13/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 10273107 | Yang et al. |
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FUNDED BY |
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APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Dongliang Yang (Ellicott City, Maryland); James E. Goodbar, III (Springfield, Virginia) |
ABSTRACT | Systems, devices and methods for receiving an item in a receptacle are disclosed. Features are disclosed for receiving and guiding an item in a receiving space of a receptacle so as to attenuate or remove the impact force of the item on the receptacle. Some embodiments of the disclosure include a bumper having an impact surface which absorbs most or all of the impact force of the item and thereby mitigates or removes the imposition of cyclic impact loads on the receptacle from repeated receipt of items. The bumper may be structurally and/or functionally de-coupled or otherwise physically separated from the receptacle such that an advantageous division of labor is created between absorbing the impact and receiving the item. This disclosure may be useful, for example, in modern industrial operations where a high volume of items are received daily, such as in mail sorting and handling operations. |
FILED | Tuesday, October 31, 2017 |
APPL NO | 15/799748 |
ART UNIT | 3656 — Material and Article Handling |
CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 1/025 (20130101) B07C 3/02 (20130101) B07C 5/00 (20130101) Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables B65H 29/26 (20130101) Original (OR) Class B65H 29/46 (20130101) B65H 31/02 (20130101) B65H 31/06 (20130101) B65H 31/08 (20130101) B65H 31/24 (20130101) B65H 39/075 (20130101) B65H 39/115 (20130101) B65H 2301/42146 (20130101) B65H 2301/422548 (20130101) B65H 2403/60 (20130101) B65H 2405/221 (20130101) B65H 2405/3312 (20130101) B65H 2701/1916 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 7/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10275969 | Hussain et al. |
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FUNDED BY |
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APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Khalid Hussain (Kansas City, Missouri); Marie Therese Dominguez (Arlington, Virginia); David E. Failor (Rockville, Maryland); William G. Ackerman (Washington, District of Columbia) |
ABSTRACT | A method of illuminating an item is disclosed. The method includes applying adhesive to the item, interspersing a taggant in the adhesive, illuminating the item with an excitation signal, sensing luminescence emitted by the taggant in response to illumination by the excitation signal, and determining the authenticity of the item based on the sensed emitted luminescence. The item can include any item benefited by authentication, and can include a postage stamp. A method of customizing an item is disclosed. This can include the steps of preparing a substrate, applying a security feature to the substrate, printing non-customized information on the substrate, receiving image information, and printing the image information on the substrate. |
FILED | Wednesday, January 13, 2016 |
APPL NO | 14/995050 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 3/4075 (20130101) Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/29 (20141001) B42D 25/45 (20141001) B42D 25/382 (20141001) B42D 25/387 (20141001) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/643 (20130101) G01N 2021/6421 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/14 (20130101) G06K 19/06028 (20130101) Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing G07D 7/20 (20130101) G07D 7/0053 (20130101) Original (OR) Class G07D 7/121 (20130101) G07D 7/1205 (20170501) Displaying; Advertising; Signs; Labels or Name-plates; Seals G09F 3/10 (20130101) G09F 3/0294 (20130101) G09F 3/0297 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10277575 | Moran et al. |
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FUNDED BY |
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APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Timothy M. Moran (National Harbor, Maryland); Jane E. Quenk (Washington, District of Columbia); Douglas Paul Glair (Baltimore, Maryland); Charles P. McLellan (Washington, District of Columbia) |
ABSTRACT | A system and method of validating an upgrade of authentication credentials includes authenticating a first user being associated with a first entity, receiving input identifying a customer name for the online account, receiving input indicating a type of identification to be presented at the validation event, receiving input indicating a transaction code associated with the validation event, and receiving input indicating a location of the validation event, and further includes authenticating a second user being associated with a second entity, providing to the second user a list of validation events for a location, receiving input selecting a validation event in the list of validation events, presenting one or more of the customer name, transaction code, and type of identification associated with the selected validation event, and receiving input indicating a result of the validation event, where a credential or token is created and assigned based on the validation event. |
FILED | Thursday, March 15, 2018 |
APPL NO | 15/922740 |
ART UNIT | 2497 — Cryptography and Security |
CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0833 (20130101) G06Q 20/40 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) Original (OR) Class H04L 63/083 (20130101) H04L 63/126 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
US 10276736 | Cho et al. |
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FUNDED BY |
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APPLICANT(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
ASSIGNEE(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
INVENTOR(S) | Benjamin Cho (Albuquerque, New Mexico); Dwight Hazlett (Rio Rancho, New Mexico); Cory Tourino (Edgewood, New Mexico); Brian Guzie (Rio Rancho, New Mexico) |
ABSTRACT | A flexible solar array for a spacecraft or aviation craft including a flexible backing substrate with conductive trace(s) formed thereon; solar cell subassemblies disposed over the flexible backing substrate, each of the solar cell subassemblies at least including a solar cell; and an adhesive layer interposed between the solar cell subassemblies and the flexible backing substrate, with the solar cell attached to the flexible backing substrate. The adhesive layer includes openings for exposing the corresponding conductive traces so that the exposed metal traces are adaptable to interconnect the solar cells of the respective adjacent solar cell subassemblies through the openings. |
FILED | Wednesday, November 21, 2018 |
APPL NO | 16/198283 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/046 (20141201) Original (OR) Class H01L 31/048 (20130101) H01L 31/0504 (20130101) H01L 31/0508 (20130101) H01L 31/02013 (20130101) H01L 31/03926 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/34 (20141201) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 10276504 | Luu et al. |
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FUNDED BY |
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APPLICANT(S) | Vivien Luu (Linthicum, Maryland); Christopher F. Kirby (Gambrills, Maryland); Brian Wagner (Baltimore, Maryland); Michael Rennie (Ashland, Virginia) |
ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
INVENTOR(S) | Vivien Luu (Linthicum, Maryland); Christopher F. Kirby (Gambrills, Maryland); Brian Wagner (Baltimore, Maryland); Michael Rennie (Ashland, Virginia) |
ABSTRACT | A method is provided of forming a superconductor interconnect structure. The method comprises forming a dielectric layer overlying a substrate, forming an interconnect opening in the dielectric layer, and moving the substrate to a deposition chamber. The method further comprises performing a cleaning process on the top surface of the dielectric layer and in the interconnect opening while in the deposition chamber, and depositing a superconducting metal in the interconnect opening while in the deposition chamber to form a superconducting element in the superconductor interconnect structure. |
FILED | Wednesday, May 17, 2017 |
APPL NO | 15/597565 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02063 (20130101) H01L 21/7684 (20130101) H01L 21/76807 (20130101) H01L 21/76814 (20130101) H01L 21/76877 (20130101) H01L 21/76891 (20130101) H01L 23/5226 (20130101) H01L 23/53285 (20130101) Original (OR) Class H01L 39/2406 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, April 30, 2019.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190430.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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