FedInvent™ Patents

Patent Details for Tuesday, May 07, 2019

This page was updated on Monday, March 27, 2023 at 05:47 AM GMT

Department of Defense (DOD)

10278599 — Body-worn system for continuous, noninvasive measurement of cardiac output, stroke volume, cardiac power, and blood pressure

US 10278599	Banet et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	SOTERA WIRELESS, INC. (San Diego, California)
ASSIGNEE(S)	SOTERA WIRELESS, INC. (San Diego, California)
INVENTOR(S)	Matthew Banet (San Diego, California); Isaac Henry (La Mesa, California); Donald Bernstein (Rancho Santa Fe, California)
ABSTRACT	The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) an impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. a TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) processing system, typically worn on the patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors.
FILED	Monday, August 20, 2018
APPL NO	16/105694
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/0008 (20130101) A61B 5/021 (20130101) A61B 5/0022 (20130101) A61B 5/029 (20130101) A61B 5/0205 (20130101) A61B 5/0245 (20130101) A61B 5/0295 (20130101) Original (OR) Class A61B 5/0535 (20130101) A61B 5/681 (20130101) A61B 5/725 (20130101) A61B 5/746 (20130101) A61B 5/0816 (20130101) A61B 5/1116 (20130101) A61B 5/02028 (20130101) A61B 5/02427 (20130101) A61B 5/6823 (20130101) A61B 5/6824 (20130101) A61B 5/6826 (20130101) A61B 5/6833 (20130101) A61B 5/7239 (20130101) A61B 5/14542 (20130101) A61B 5/14551 (20130101) A61B 2562/04 (20130101) Electric Digital Data Processing G06F 19/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10278647 — Method and apparatus for removing motion artifacts from biomedical signals

US 10278647	Salehizadeh et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	University of Connecticut (Farmington, Connecticut)
ASSIGNEE(S)	University of Connecticut (Farmington, Connecticut)
INVENTOR(S)	Seyed M. A. Salehizadeh (Coventry, Connecticut); Ki H. Chon (Mansfield Center, Connecticut); Yeonsik Noh (Willington, Connecticut)
ABSTRACT	A method and corresponding apparatus employ a time-varying spectral analysis approach for reconstructing a heart-related signal that includes motion artifacts. The motion artifacts are produced by motion of a biomedical sensor relative to a sensing location. By comparing time-varying spectra of the heart-related signal and a motion signal, those frequency peaks resulting from the motion artifacts may be suppressed in a time-varying spectrum of the heart-related signal. The time-varying spectral analysis based approach enables the heart-related signal to be reconstructed with accuracy by suppressing the motion artifacts. Example applications for the method and corresponding apparatus include training aids (e.g., runners' heart-rate monitors) and hospital patient heart-rate monitors.
FILED	Thursday, June 09, 2016
APPL NO	15/178089
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/046 (20130101) A61B 5/0077 (20130101) A61B 5/0205 (20130101) A61B 5/0245 (20130101) A61B 5/0464 (20130101) A61B 5/721 (20130101) Original (OR) Class A61B 5/725 (20130101) A61B 5/1102 (20130101) A61B 5/02405 (20130101) A61B 5/02416 (20130101) A61B 5/02427 (20130101) A61B 5/02438 (20130101) A61B 5/04012 (20130101) A61B 5/6824 (20130101) A61B 5/7239 (20130101) A61B 5/7253 (20130101) A61B 5/7275 (20130101) A61B 5/14552 (20130101) A61B 2503/10 (20130101) A61B 2505/07 (20130101) A61B 2505/09 (20130101) A61B 2562/0219 (20130101)
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10278708 — Compression device

US 10278708	Demas et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Swift-Strap LLC (Cambridge, Massachusetts)
ASSIGNEE(S)	SWIFT-STRAP LLC (Cambridge, Massachusetts)
INVENTOR(S)	Nickolas Peter Demas (Manlius, New York); Anton Stuart Hunt (Houston, Texas); Tyler T. Hamer (Cambridge, Massachusetts); Zaid Zayyad (Cambridge, Massachusetts); James F. Connor (Cambridge, Massachusetts); Julio C. Guerrero (Cambridge, Massachusetts); Pranay Jain (Delhi, India)
ABSTRACT	A compression device, useful for applying circumferential compression to an object, for example, as a tourniquet to occlude blood flow in a hemorrhaging extremity, is provided. The device includes a buckle assembly, first and second guidance slides, a connecting member between the first and second guidance slides, and a strap. Each end of the strap is anchored to a guidance slide. From each of the anchored ends, the strap passes through the buckle assembly, forming outer segments. The strap then returns along respective insides of the outer segments and through the guidance slides, forming inner segments. The buckle assembly, inner segments and connecting member form a loop for placing about an object, an inner circumference of the loop being adjustable by pulling on a portion of the strap located along the outside of the connecting member and between the two guidance slides to tighten the loop around the object.
FILED	Tuesday, February 03, 2015
APPL NO	15/116488
ART UNIT	3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/1322 (20130101) A61B 17/1327 (20130101) Original (OR) Class
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10279009 — Histone deacetylase (HDAC) inhibitor up-regulates car expression and targeted antigen intensity, increasing antitumor efficacy

US 10279009	Vera Valdes et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Baylor College of Medicine (Houston, Texas)
ASSIGNEE(S)	Baylor College of Medicine (Houston, Texas)
INVENTOR(S)	Juan Fernando Vera Valdes (Bellaire, Texas); Malcolm Brenner (Bellaire, Texas); Usanarat Anurathapan (Houston, Texas)
ABSTRACT	Embodiments of the invention employ methods and compositions for enhancing potency of immune cells that express one or more therapeutic proteins. In certain cases, the methods modulate expression of a CAR transgene in an immune cell, such as a T cell. Specific embodiments employ the exposure of cells and/or individuals to be treated with the cells with an effective amount of at least one agent that upregulates expression of the therapeutic protein, such as a mitogen, histone deacetylase inhibitor, and or DNA methyltransferase inhibitor.
FILED	Friday, July 18, 2014
APPL NO	14/335766
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/706 (20130101) A61K 31/706 (20130101) A61K 35/17 (20130101) A61K 38/164 (20130101) A61K 38/177 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) C12N 2501/06 (20130101) C12N 2501/065 (20130101) C12N 2510/00 (20130101)
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10279011 — Methods of use for IL-22 promoting rejuvenation of thymic and bone marrow function

US 10279011	Dudakov et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S)	MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
INVENTOR(S)	Jarrod Dudakov (New York, New York); Marcel van den Brink (New York, New York); Alan Hanash (New York, New York)
ABSTRACT	The present invention provides methods and compositions for the use of IL-22 to promote thymic growth following thymic insult. In particularly preferred embodiments, the present invention provides methods of using therapeutic IL-22 compositions for treating patients with thymic atrophy and alterations in bone marrow derived white blood cells, including cancer patients undergoing chemotherapy, patients exposed to radiation (i.e. cancer therapy, nuclear disaster, terrorist attack, etc.), patients with HIV infections/AIDS, patients with organ transplantation, aging patients, and the like. In a further embodiment, therapeutic IL-22 compositions are contemplated as a prophylactic to boost immune response when additional T-cell function is needed, i.e. to boost immune response during vaccination.
FILED	Monday, June 15, 2015
APPL NO	14/739743
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/20 (20130101) Original (OR) Class
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10279094 — Endovascular variable aortic control catheter

US 10279094	Williams et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S)	United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Timothy K. Williams (Davis, California); Lucas Paul Neff (Davis, California); James B. Sampson (Davis, California)
ABSTRACT	Endovascular variable aortic control catheters (EVACC) are provided that are adapted to augment upstream blood pressure and regulate downstream blood flow for patients in shock. The EVACC devices provide improved treatment for truncal wounds, which may be used for example on a battlefield, thereby increasing survivability of injured soldiers. The devices are a catheter-based system having a proximal hand piece for controlled deployment of the device through a delivery sheath. A collapsible, wire framework supports an expandable and collapsible occlusion barrier. The wire basket and occlusion barrier expand to fit within the lumen of the aorta. Various movable elements are used to adjust an adjustable passageway to regulate controlled anterograde blood flow.
FILED	Thursday, January 07, 2016
APPL NO	14/990465
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/12 (20130101) A61M 1/125 (20140204) Original (OR) Class A61M 1/1008 (20140204) A61M 1/1018 (20140204) A61M 1/1037 (20130101) A61M 1/1086 (20130101) A61M 2205/3334 (20130101)
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10279098 — Blood treatment device priming devices, methods, and systems

US 10279098	Brugger et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	NxStage Medical, Inc. (Lawrence, Massachusetts)
ASSIGNEE(S)	NxStage Medical, Inc. (Lawrence, Massachusetts)
INVENTOR(S)	James M. Brugger (Newburyport, Massachusetts); David Desouza (Essex, Massachusetts)
ABSTRACT	Simple-to-use systems, methods, and devices for priming replacement blood treatment devices, for swapping the blood treatment devices out, for replacing swapped-out blood treatment devices, and other related operations are described. In embodiments, a blood treatment device can be primed while a therapy is still running. When the replacement blood treatment device is needed, the therapy can be stopped momentarily (less than a minute) for the rapid and safe swap of the blood treatment device. Blood loss can be minimized. The down time from therapy can be minimized.
FILED	Thursday, April 07, 2016
APPL NO	15/564719
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3629 (20140204) A61M 1/3643 (20130101) Original (OR) Class A61M 1/3644 (20140204) A61M 1/3646 (20140204) A61M 1/3652 (20140204) A61M 1/3672 (20130101) A61M 39/10 (20130101) A61M 2205/702 (20130101) A61M 2205/705 (20130101) A61M 2205/707 (20130101) A61M 2205/3331 (20130101)
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10279156 — Auto-replenishing, wound-dressing apparatus and method

US 10279156	Bhavaraju et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Aplion Medical Corporation (Salt Lake City, Utah)
ASSIGNEE(S)	Aplion Medical, LLC (Salt Lake City, Utah)
INVENTOR(S)	Sai Bhavaraju (West Jordan, Utah); John Howard Gordon (Salt Lake City, Utah); Jeremy Heiser (Salt Lake City, Utah); Ashok V Joshi (Salt Lake City, Utah); Troy C Dayton (Syracuse, Utah)
ABSTRACT	Apparatus and methods to treat skin defects include a pump with reservoirs for a pressurization gas and a fluid. Upon activation, the pump generates a gas introduced into the gas reservoir, a movable wall of which displaces a movable wall of a fluid source, thus dispensing the fluid into the dressing to spread throughout irrespective of orientation of the dressing, maintaining a transport fluid (e.g. carrier) in the dressing and in contact with a skin defect being treated. The dressing may have a distribution network, and multiple members, dispensing the fluid into the dressing and in contact with a skin defect being treated.
FILED	Monday, June 16, 2014
APPL NO	14/305995
ART UNIT	3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/00068 (20130101) A61F 2013/002 (20130101) A61F 2013/0017 (20130101) A61F 2013/00174 (20130101) A61F 2013/00268 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 35/00 (20130101) Original (OR) Class A61M 35/006 (20130101)
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10279157 — Stress shield and infection control for a skin-implant interface

US 10279157	Kuiken et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Medical Research Acquisition Activity (USAMRAA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Rehabilitation Institute of Chicago (Chicago, Illinois)
ASSIGNEE(S)	Rehabilitation Institute of Chicago (Chicago, Illinois)
INVENTOR(S)	Todd A. Kuiken (Oak Park, Illinois); Gregory A. Dumanian (Chicago, Illinois); Jason M. Souza (Chicago, Illinois)
ABSTRACT	Embodiments for superficial tissue compliance modulation and negative pressure wound therapy for stabilization of a chronic percutaneous implant are disclosed. An external cap is coupled to a compliance gradient of progressively decreasing stiffness. Together the external cap and compliance gradient act as a stress shield that allows forces that would otherwise act on the skin at the skin-implant interface to be dissipated over a larger area. In addition, negative pressure and fluids may be applied through negative pressure and fluid adapters, respectively, to the skin-implant interface, the status of which may be further monitored through the use of one or more sensors.
FILED	Friday, March 14, 2014
APPL NO	14/213318
ART UNIT	3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/0023 (20130101) A61M 1/0056 (20130101) A61M 1/0088 (20130101) A61M 39/10 (20130101) Original (OR) Class A61M 39/0247 (20130101) A61M 2039/0261 (20130101) A61M 2210/02 (20130101)
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10279204 — Serviceable cartridge assembly for respirator exhalation unit

US 10279204	Wheatley et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	D. Wheatley Enterprises, Inc. (Aberdeen, Maryland)
ASSIGNEE(S)	D. WHEATLEY ENTERPRISES, INC. (Belcamp, Maryland)
INVENTOR(S)	David Wheatley (Aberdeen, Maryland); Patrick Hulbert (Aberdeen, Maryland); Stanley Rodowsky (Aberdeen, Maryland)
ABSTRACT	Disclosed is a modular serviceable cartridge assembly for a respirator exhalation unit that is simple in construction and that allows quick-connect of an exhalation valve cartridge in a mask to minimize the need for reconfiguration when changing personal protective equipment, and that allows for easy removal and breakdown for servicing and/or replacement of individual components of the exhalation valve without modifying or replacing other elements of the protective mask. The assembly may be convertible from a negative pressure valve assembly to a positive pressure valve assembly, and vice versa, and a grill may be provided on an outlet side of the cartridge assembly, the rotation of which converts the assembly from a negative pressure valve to a positive pressure valve.
FILED	Friday, November 14, 2014
APPL NO	14/541780
ART UNIT	3785 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Devices, Apparatus or Methods for Life-saving A62B 9/02 (20130101) A62B 9/027 (20130101) A62B 18/00 (20130101) A62B 18/02 (20130101) A62B 18/10 (20130101) Original (OR) Class A62B 18/025 (20130101)
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10279394 — Synthesis of chiral nanoparticles using circularly polarized light

US 10279394	Kotov et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Nicholas A. Kotov (Ypsilanti, Michigan); Jihyeon Yeom (Ypsilanti, Michigan)
ABSTRACT	New methods of forming chiral nanoparticles (e.g., nano structures) are provided. The method comprises directing circular polarized light (CPL) towards a nanoparticle precursor to cause a photo induced reaction of the nanoparticle precursor and induce chirality to form a stable chiral nanoparticle. In this manner, CPL is used to template chirality onto nanoparticles without use of any chiral component or chiral ligands for inducing chirality to the particle in such a method. The nanoparticles may include a variety of light-absorbing materials (e.g., CdTe, CdS, Au, and the like). Such methods provide a rapid, simple, and inexpensive way of forming chiral nanoparticles that have long term chiral stability.
FILED	Friday, November 13, 2015
APPL NO	14/940845
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 9/24 (20130101) Original (OR) Class Non-metallic Elements; Compounds Thereof; C01B 19/007 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/17 (20130101) C01P 2006/60 (20130101)
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10279444 — Laser assisted machining system for ceramics and hard materials

US 10279444	Santner et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Tank-Automotive and Armaments Command (TACOM)
APPLICANT(S)	Joseph S. Santner (Munster, Indiana); Federico M. Sciammarella (DeKalb, Illinois); Stefan Kyselica (Glen Ellyn, Illinois)
ASSIGNEE(S)	Board of Trustees of Northern Illinois University (DeKalb, Illinois)
INVENTOR(S)	Joseph S. Santner (Munster, Indiana); Federico M. Sciammarella (DeKalb, Illinois); Stefan Kyselica (Glen Ellyn, Illinois)
ABSTRACT	A method for laser assisted machining is provided, by utilizing a computer to develop interrelated heating and machining plans, from a variety of input data describing the material to be machined, the properties of lasers and pyrometers used for heating the material, and computer models of the machining arrangement, workpiece and final part to be produced. An iterative process continues until the machining and heating plans result in the cutting zone of the workpiece being maintained at a desired temperature with no obstruction in the line-of-sight of at least one laser and pyrometer throughout the machining process, while also maintaining the cutting tool at or below a desired maximum temperature.
FILED	Monday, December 22, 2014
APPL NO	14/579744
ART UNIT	3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0093 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 25/006 (20130101) Original (OR) Class Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/182 (20130101) G05B 2219/45165 (20130101)
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10279482 — Braking and regeneration control in a legged robot

US 10279482	Khripin et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Defense Contract Management Agency (DCMA) Department of the Army (DOA)
APPLICANT(S)	Boston Dynamics, Inc. (Waltham, Massachusetts)
ASSIGNEE(S)	Boston Dynamics, Inc. (Waltham, Massachusetts)
INVENTOR(S)	Alex Khripin (Waltham, Massachusetts); Stephen Berard (Waltham, Massachusetts); Alfred Anthony Rizzi (Waltham, Massachusetts)
ABSTRACT	An example robot includes a hydraulic actuator cylinder controlling motion of a member of the robot. The hydraulic actuator cylinder comprises a piston, a first chamber, and a second chamber. A valve system controls hydraulic fluid flow between a hydraulic supply line of pressurized hydraulic fluid, the first and second chambers, and a return line. A controller may provide a first signal to the valve system so as to begin moving the piston based on a trajectory comprising moving in a forward direction, stopping, and moving in a reverse direction. The controller may provide a second signal to the valve system so as to cause the piston to override the trajectory as it moves in the forward direction and stop at a given position, and then provide a third signal to the valve system so as to resume moving the piston in the reverse direction based on the trajectory.
FILED	Thursday, December 18, 2014
APPL NO	14/574471
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 5/00 (20130101) B25J 9/20 (20130101) Original (OR) Class Motor Vehicles; Trailers B62D 57/032 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 9/09 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101)
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10279519 — Mold assembly and method of molding a component

US 10279519	Bartlett et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Surface Warfare Center (NSWC)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	David Bartlett (Mitchell, Indiana); Elizabeth O'Neill (Washington, Indiana); Robert Moser (Heltonville, Indiana); Roger Dickerhoof (Bloomington, Indiana); Carl Miller (Bedford, Indiana); Joshua Jeffers (Loogootee, Indiana); Bryan Woosley (Bedford, Indiana); James Merryfield (Bedford, Indiana)
ABSTRACT	A mold assembly includes a first upper portion, a second upper portion, and a base removably coupled to each other. A method of manufacturing an electrical connector with the mold assembly includes preheating a resin, mixing the resin with a hardener, preheating the mold assembly, injecting the resin hardener mixture into the mold assembly, and curing the resin hardener mixture.
FILED	Wednesday, December 30, 2015
APPL NO	14/984080
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0001 (20130101) B29C 45/14639 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/36 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/00 (20130101)
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10280033 — Dispensing from an apparatus

US 10280033	Scott
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Jeremy David Scott (Aberdeen, Maryland)
ABSTRACT	Various embodiments are described that relate to dispensing from an apparatus. The apparatus can be a cable dispensing apparatus that is attached to a vehicle. As the vehicle travels, the apparatus can lay or retract cable. The rate of this laying or retracting can be based, at least in part, on a travel condition of the vehicle.
FILED	Thursday, January 28, 2016
APPL NO	15/008532
ART UNIT	3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables B65H 51/30 (20130101) Original (OR) Class B65H 75/425 (20130101) B65H 75/4484 (20130101) Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 11/02 (20130101)
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10280204 — Electroactive biopolymer optical and electro-optical devices and method of manufacturing the same

US 10280204	Kaplan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	TUFTS UNIVERSITY (Medford, Massachusetts)
ASSIGNEE(S)	Tufts University (Medford, Massachusetts)
INVENTOR(S)	David L. Kaplan (Concord, Massachusetts); Fiorenzo Omenetto (Lexington, Massachusetts); Brian Lawrence (Minneapolis, Minnesota); Mark Cronin-Golomb (Reading, Massachusetts)
ABSTRACT	A method of manufacturing a biopolymer optical device includes providing a polymer, providing a substrate, casting the polymer on the substrate, and enzymatically polymerizing an organic compound to generate a conducting polymer between the provided polymer and the substrate. The polymer may be a biopolymer such as silk and may be modified using organic compounds such as tyrosines to provide a molecular-level interface between the provided bulk biopolymer of the biopolymer optical device and a substrate or other conducting layer via a tyrosine-enzyme polymerization. The enzymatically polymerizing may include catalyzing the organic compound with peroxidase enzyme reactions. The result is a carbon-carbon conjugated backbone that provides polymeric “wires” for use in polymer and biopolymer optical devices. An all organic biopolymer electroactive material is thereby provided that provides optical functions and features.
FILED	Thursday, February 18, 2016
APPL NO	15/046903
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/02 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0074 (20130101) B29D 11/00663 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Peptides C07K 14/43586 (20130101) Original (OR) Class Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2211/04 (20130101) D10B 2401/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/544 (20130101) G01N 33/5436 (20130101) G01N 33/54373 (20130101) G01N 33/54386 (20130101) G01N 2333/43578 (20130101) Optical Elements, Systems, or Apparatus G02B 1/04 (20130101) G02B 1/005 (20130101) G02B 1/06 (20130101) G02B 1/041 (20130101) G02B 1/045 (20130101) G02B 1/046 (20130101) G02B 5/18 (20130101) G02B 6/138 (20130101) G02B 2006/1213 (20130101) G02B 2006/12102 (20130101) G02B 2006/12104 (20130101) G02B 2006/12107 (20130101) G02B 2006/12171 (20130101)
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10280208 — TMIGD2 and its derivatives as blockers or binders of cancer-expressed HHLA2 for immunotherapies

US 10280208	Zang et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York)
ASSIGNEE(S)	Albert Einstein College of Medicine (Bronx, New York)
INVENTOR(S)	Xingxing Zang (New York, New York); Jordan M. Chinai (Bronx, New York); Murali Janakiram (Brooklyn, New York); Steven C. Almo (Pelham, New York); Andras Fiser (New York, New York)
ABSTRACT	Provided are methods of treating an HHLA2-bearing tumor in a subject with a fusion protein comprising an IgV-like domain of a TMIGD2 sufficient to treat the HHLA2-bearing tumor. A fusion protein comprising an IgV-like domain of a TMIGD2 and related compositions and encoding nucleic acids are also provided.
FILED	Friday, April 24, 2015
APPL NO	15/300294
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/70503 (20130101) Original (OR) Class C07K 2319/30 (20130101)
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10280310 — Optical applications of nanosphere metasurfaces

US 10280310	Fontana et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jake Fontana (Alexandria, Virginia); Jawad Naciri (Arlington, Virginia); Banahalli R. Ratna (Alexandria, Virginia); Nicholas A. Charipar (Alexandria, Virginia); Alberto Piqué (Crofton, Maryland)
ABSTRACT	A monolayer film of nanoparticles can formed from a fluid mixture by combining nanoparticles dispersed in water with a water-miscible organic solvent and a molecular ligand comprising a head group with affinity for the nanoparticle, and introducing the fluid mixture to a substrate in the presence of an air/fluid interface, thereby causing a monolayer film of nanoparticles to form on the substrate. Such monolayers films can include metallic nanoparticles such as gold, and possess substantially uniform spacing over at least a one centimeter length scale. The films are metasurfaces effective to cause a range of linear refractive index of from around unity at 700 nm to 10 at 1500 nm. Such metasurfaces might find utility, for example, as ultrafast (picosecond scale) switches at wavelengths useful for telecommunications.
FILED	Monday, July 24, 2017
APPL NO	15/657623
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0025 (20130101) B22F 1/0062 (20130101) B22F 7/04 (20130101) B22F 7/08 (20130101) B22F 2007/042 (20130101) B22F 2301/255 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 156/11 (20150115)
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10280317 — Enhanced conductivity, adhesion and environmental stability of printed graphene inks with nitrocellulose

US 10280317	Hersam et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Research Laboratory (AFRL) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Mark C. Hersam (Wilmette, Illinois); Ethan B. Secor (Evanston, Illinois); Theodore Z. Gao (Evanston, Illinois)
ABSTRACT	Graphene ink compositions comprising nitrocellulose and related methods of use comprising either thermal or photonic annealing.
FILED	Friday, July 07, 2017
APPL NO	15/644326
ART UNIT	2853 — Printing/Measuring and Testing
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/01 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/14 (20130101) C09D 11/36 (20130101) C09D 11/037 (20130101) Original (OR) Class C09D 11/52 (20130101) C09D 11/322 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/00 (20130101)
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10280342 — Adhesive materials and methods of making and using the same

US 10280342	Waite et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Herbert J. Waite (Goleta, California); B. Kollbe Ahn (Goleta, California); Craig J. Hawker (Santa Barbara, California); Jinhwa Heo (Suwon, South Korea); Taegon Kang (Suwon, South Korea)
ABSTRACT	A compound of formula (I): can be used as a monomer for making an underwater adhesive polymer. The compound of formula (I) can be prepared using eugenol as a starting material.
FILED	Wednesday, July 30, 2014
APPL NO	14/908956
ART UNIT	1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 33/20 (20130101) C07C 33/025 (20130101) C07C 33/26 (20130101) C07C 33/30 (20130101) C07C 39/19 (20130101) C07C 39/20 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1804 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 12/24 (20130101) C08F 16/26 (20130101) C08F 30/08 (20130101) C08F 220/30 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 4/06 (20130101) C09J 125/18 (20130101) C09J 129/02 (20130101) C09J 143/04 (20130101) Original (OR) Class
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10280369 — Thermal barrier mixtures and uses thereof

US 10280369	Neef et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S)	Charles J. Neef (Bastrop, Texas); John Lee Massingill, Jr. (San Marcos, Texas); Clois E. Powell (Seguin, Texas)
ABSTRACT	Thermal barrier mixtures and method of making the thermal barrier mixtures are described herein. The thermal barrier mixtures may be used to make thermal barrier coatings. Thermal barrier mixture may include halloysite and one or more silicon compounds.
FILED	Monday, April 22, 2013
APPL NO	14/395720
ART UNIT	1768 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/13 (20130101) C01P 2006/32 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/0081 (20130101) C09C 1/405 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/18 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 21/02 (20130101) Original (OR) Class C09K 21/12 (20130101)
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10280485 — Method for creating porous structures by particle expansion

US 10280485	Atwater et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Millersville University of Pennsylvania (Millersvile, Pennsylvania)
ASSIGNEE(S)	Millersville University of Pennsylvania (Millersville, Pennsylvania); The United State Of America As Represented By The Secretary Of The Army (Washington, District of Columbia)
INVENTOR(S)	Mark Andrew Atwater (Quarryville, Pennsylvania); Kris Allen Darling (Havre de Grace, Maryland); Mark Allen Tschopp, Jr. (Bel Air, Maryland)
ABSTRACT	A process for producing a metal foam. The process includes mechanically working a metallic powder such that oxide particles are finely dispersed within a metallic matrix of the metallic particles that make up the metallic powder. The mechanically worked metallic powder is then annealed in a reducing atmosphere, which in turn reduces the oxide particles within the metallic particles such that H₂O gas molecules (steam) are formed within the metallic matrix and intraparticle porosity is produced.
FILED	Tuesday, July 28, 2015
APPL NO	14/811049
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0085 (20130101) B22F 1/0085 (20130101) B22F 3/1143 (20130101) B22F 3/1143 (20130101) B22F 3/1143 (20130101) B22F 2009/043 (20130101) B22F 2009/043 (20130101) B22F 2009/043 (20130101) B22F 2201/03 (20130101) B22F 2201/05 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Alloys C22C 1/08 (20130101) Original (OR) Class
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10280761 — Three dimensional airfoil micro-core cooling chamber

US 10280761	Vu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Ky H. Vu (East Hartford, Connecticut); Brandon W. Spangler (Vernon, Connecticut)
ABSTRACT	A component for use in a gas turbine engine comprises a body and a micro-core cooling circuit embedded within the body. The micro-core circuit has a variation in either the thickness or contoured surface, away from a generally planar shape to a non-planar shape.
FILED	Thursday, October 01, 2015
APPL NO	14/872272
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) Original (OR) Class F01D 5/187 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/202 (20130101) F05D 2260/2214 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/04 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101)
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10280779 — Plug seal for gas turbine engine

US 10280779	Simonds
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Mark E. Simonds (Cape Neddick, Maine)
ABSTRACT	An example seal includes, among other things, a plug body to limit flow through an axially extending interface between a first component and a second component, the plug body to flow when positioned within both a cavity of the first component and a cavity of the second component.
FILED	Monday, September 08, 2014
APPL NO	14/916752
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 11/005 (20130101) Original (OR) Class Non-positive-displacement Pumps F04D 29/083 (20130101) F04D 29/542 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/60 (20130101) F05D 2240/11 (20130101)
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10280787 — Monitoring rotating machinery using radio frequency probes

US 10280787	Pratt et al.
FUNDED BY	Central Intelligence Agency (CIA) Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Thomas G. Pratt (Niles, Michigan); Jeffrey G. Mueller (South Bend, Indiana); Robert D. Kossler (South Bend, Indiana); Neil Dodson (South Bend, Indiana); Scott C. Morris (Granger, Indiana)
ASSIGNEE(S)	University of Notre Dame Du Lac (South Bend, Indiana)
INVENTOR(S)	Thomas G. Pratt (Niles, Michigan); Jeffrey G. Mueller (South Bend, Indiana); Robert D. Kossler (South Bend, Indiana); Neil Dodson (South Bend, Indiana); Scott C. Morris (Granger, Indiana)
ABSTRACT	Systems and methods for monitoring rotating machinery are disclosed. Transmitter and receiver antennas can be provided with access to the rotating machinery. At least one receiver signal resulting from at least one transmitter signal that has propagated through a portion of the rotating machinery can be obtained. A first signal pair can be formed from a first receiver signal and a first transmitter signal, or from first and second receiver signals obtained from spatially-separated receiver antennas, or from first and second receiver signals which are attributable to different transmitter signals. Amplitude and phase information of a plurality of frequency components for each signal in the first signal pair can be determined. A set of comparison values for the first signal pair can be determined by comparing respective frequency component phases or respective frequency component amplitudes. A characteristic of the rotating machinery can then be analyzed using the comparison values.
FILED	Monday, November 09, 2015
APPL NO	14/936523
ART UNIT	2631 — Digital Communications
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 21/003 (20130101) Original (OR) Class Transmission H04B 1/40 (20130101)
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10280791 — Tuned mass damper for tubes

US 10280791	Peters et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Donald W. Peters (Colchester, Connecticut); Andreas Sadil (Newington, Connecticut); Nico M. Rappoli (Middletown, Connecticut); Amarnath Ramlogan (Glastonbury, Connecticut)
ABSTRACT	A tuned mass damper for reducing vibration on a component includes a shaft connector member configured to be coupled to the component and a cable termination member. The tuned mass damper also includes at least one cable coupled to the shaft connector member and to the cable termination member such that vibration of the component is transferred to the at least one cable via the shaft connector member and increased or decreased by the at least one cable.
FILED	Monday, July 11, 2016
APPL NO	15/207207
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/04 (20130101) Original (OR) Class F01D 25/30 (20130101) F01D 25/162 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/20 (20130101) F02C 7/22 (20130101) Jet-propulsion Plants F02K 3/10 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2230/237 (20130101) F05D 2260/96 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 7/023 (20130101) F16F 7/116 (20130101)
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10280792 — Bore basket for a gas powered turbine

US 10280792	Gons
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	William M. Gons (Juno Beach, Florida)
ABSTRACT	Gas turbine engines include bore baskets to facilitate rotor bore cooling. One such bore basket for utilization in a gas turbine engine includes two cylinders that guide a cooling flow through a bore opening. The cylinders define an axially aligned gap that further directs fluid flow when a cooling fluid is injected into the system.
FILED	Friday, February 20, 2015
APPL NO	14/627030
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/085 (20130101) F01D 25/12 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/20 (20130101) F05D 2260/205 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101)
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10280793 — Insert and standoff design for a gas turbine engine vane

US 10280793	Vu
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Ky H. Vu (East Hartford, Connecticut)
ABSTRACT	A component for a gas turbine engine according to an exemplary aspect of the present disclosure includes, among other things, a platform, an airfoil that extends from the platform, and an insert positioned such that a first portion of the insert extends relative to a surface of the platform and a second portion extends inside the airfoil. A standoff supports the insert above the surface.
FILED	Thursday, August 28, 2014
APPL NO	15/021998
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/189 (20130101) F01D 9/041 (20130101) F01D 9/065 (20130101) F01D 25/12 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/60 (20130101) F05D 2240/81 (20130101) F05D 2260/201 (20130101)
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10281153 — Combustor assembly

US 10281153	Hannwacker et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	David Andrew Hannwacker (Torrance, California); Stephen John Howell (West Newbury, Massachusetts)
ABSTRACT	A combustor assembly includes a first combustion chamber member and a second combustion chamber member. The first and second combustion chamber members are each formed of a CMC material and include adjacently positioned coupling flanges. A mounting assembly includes a pair of mounting flanges positioned on opposite sides of the coupling flanges of first and second combustion chamber members. An attachment member of the mounting assembly clamps the pair of mounting flanges together to mount the first and second combustion chamber members.
FILED	Thursday, February 25, 2016
APPL NO	15/053460
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/20 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/007 (20130101) Original (OR) Class F23R 3/50 (20130101) F23R 3/60 (20130101) F23R 2900/00005 (20130101) F23R 2900/00017 (20130101)
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10281227 — Cold spray and WAAM methods for manufacturing gun barrels

US 10281227	Champagne et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Victor Champagne (Dudley, Massachusetts); Adam Jacob (Broadheadsville, Pennsylvania); Frank Dindl (Newton, New Jersey); Aaron Nardi (East Granby, Connecticut); Michael Klecka (Coventry, Connecticut)
ABSTRACT	A method for manufacturing a gun barrel with a cold spray process. The method includes the use of a mandrel having a tubular body and being made of a material with properties suited to use with gun barrel manufacture and materials and cold spray processes.
FILED	Friday, April 21, 2017
APPL NO	15/493913
ART UNIT	1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 24/04 (20130101) Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/04 (20130101) Original (OR) Class
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10281242 — Material and process for coupling impulses and shockwaves into solids

US 10281242	Knies et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	David L. Knies (Marbury, Maryland); Kenneth S. Grabowski (Alexandria, Virginia); Alex E. Moser (Fort Washington, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	David L. Knies (Marbury, Maryland); Kenneth S. Grabowski (Alexandria, Virginia); Alex E. Moser (Fort Washington, Maryland)
ABSTRACT	An armor system includes an armor plate, and an appliqué affixed to an exterior of the armor plate, wherein the appliqué has a density increasing in a direction towards the armor plate and configured to minimize reflection of a blast wave from the armor plate. Also disclosed are method of making such an armor system.
FILED	Tuesday, June 18, 2013
APPL NO	13/920807
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/04 (20130101) Original (OR) Class F41H 5/013 (20130101) Blasting F42D 5/045 (20130101)
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10281257 — Method and apparatus for remote sensing of objects utilizing radiation speckle

US 10281257	Shirley
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Lyle G. Shirley (Boxborough, Massachusetts)
ASSIGNEE(S)
INVENTOR(S)	Lyle G. Shirley (Boxborough, Massachusetts)
ABSTRACT	Disclosed are systems and methods to extract information about the size and shape of an object by observing variations of the radiation pattern caused by illuminating the object with coherent radiation sources and changing the wavelengths of the source. Sensing and image-reconstruction systems and methods are described for recovering the image of an object utilizing projected and transparent reference points and radiation sources such as tunable lasers. Sensing and image-reconstruction systems and methods are also described for rapid sensing of such radiation patterns. A computational system and method is also described for sensing and reconstructing the image from its autocorrelation. This computational approach uses the fact that the autocorrelation is the weighted sum of shifted copies of an image, where the shifts are obtained by sequentially placing each individual scattering cell of the object at the origin of the autocorrelation space.
FILED	Tuesday, January 31, 2017
APPL NO	15/420555
ART UNIT	2886 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0077 (20130101) A61B 5/117 (20130101) A61B 2576/00 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02004 (20130101) G01B 9/02005 (20130101) G01B 9/02069 (20130101) G01B 9/02083 (20130101) G01B 9/02094 (20130101) Original (OR) Class G01B 9/02096 (20130101) G01B 11/14 (20130101) G01B 11/2441 (20130101) Electric Digital Data Processing G06F 21/32 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/629 (20130101) G06K 9/2018 (20130101) Image Data Processing or Generation, in General G06T 7/55 (20170101) G06T 7/521 (20170101) G06T 2207/10152 (20130101)
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10281281 — Decision support and control systems including various graphical user interfaces configured for displaying multiple transit options for a platform with respect to hazard and objects and related methods

US 10281281	Ward
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Surface Warfare Center (NSWC)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
INVENTOR(S)	Matthew K. Ward (Ventura, California)
ABSTRACT	A decision support and control system including a Graphical User Interface configured for displaying multiple transit options for a platform with respect to hazard and objects along with accompanying methods is provided. The methods and apparatus may receive information from a variety of systems such as a ship's radar and electro-optical systems to derive threat information, and a ship's weapon systems that may include both lethal and non-lethal weapons, the maximum and minimum range of the weapons, the accuracy characteristics of the weapons, and the maximum and minimum azimuth angles that the weapons can engage. The apparatus and methods may provide multiple transit options for a ship that provides tactical suggestions for a ship to successfully defend itself against a swarm attack by multiple incoming threats. Such tactical suggestions illustratively account for the various paths being presented and may also present performance metrics such as associated probabilities of success.
FILED	Monday, August 29, 2016
APPL NO	15/250604
ART UNIT	3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/203 (20130101) Original (OR) Class Electric Digital Data Processing G06F 3/14 (20130101) G06F 3/147 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 2354/00 (20130101) G09G 2380/10 (20130101)
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10281385 — Device for laser analysis and separation (LAS) of particles

US 10281385	Hart et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Sean J. Hart (Keswick, Virginia); Alexander V. Terray (Alexandria, Virginia); Colin G. Hebert (Laurel, Maryland)
ABSTRACT	A device includes a collimated light source operable to generate a collimated light source beam, which includes a beam direction. The device includes a first channel in a first plane and a second channel in a second plane different from the first plane. The second channel communicates with the first channel and includes a flow direction. The second channel is oriented to receive the collimated light source beam. The device includes a third channel in a third plane different from the second plane and communicates with the second channel. The collimated light source beam is oriented to enter a cross-section of the first channel, then to pass through the second channel, and then to enter a cross-section of the third channel such that the beam direction is opposite to the flow direction in the second channel. The device includes a focused particle stream nozzle operably connected to the first channel.
FILED	Wednesday, January 25, 2017
APPL NO	15/415029
ART UNIT	1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 21/0009 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/0627 (20130101) B01L 2300/0864 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1404 (20130101) Original (OR) Class G01N 15/1434 (20130101) G01N 15/1459 (20130101) G01N 33/4833 (20130101) G01N 2015/149 (20130101) G01N 2015/0288 (20130101) G01N 2015/1006 (20130101) G01N 2015/1415 (20130101)
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10281405 — Ambient desorption-optical emission spectroscopy using a microplasma desorption/excitation source

US 10281405	Marcus et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	CLEMSON UNIVERSITY (Clemson, South Carolina)
ASSIGNEE(S)	Clemson University Research Foundation (Clemson, South Carolina)
INVENTOR(S)	Richard Kenneth Marcus (Clemson, South Carolina); Htoo Wai Paing (Charleston, South Carolina); Xinyan Zhang (Central, South Carolina)
ABSTRACT	Described is an elemental analysis system and methods for use thereof that can be utilized in examination of samples in their native state. The systems utilize a liquid sampling—atmospheric pressure glow discharge (LS-APGD) device for ambient desorption sampling and excitation of a solid sample in combination with optical emission detection. This approach can find application across a broad spectrum of analytical challenges including metals, soils, and volume-limited samples.
FILED	Friday, January 06, 2017
APPL NO	15/399916
ART UNIT	2877 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/67 (20130101) G01N 21/69 (20130101) Original (OR) Class G01N 2201/0221 (20130101)
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10281583 — Detection of satellite system anomalies

US 10281583	Leibner et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The MITRE Corporation (McLean, Virginia)
ASSIGNEE(S)	The MITRE Corporation (McLean, Virginia)
INVENTOR(S)	Darrow Paine Leibner (Arlington, Virginia); Robert James Reynolds (North Reading, Massachusetts); Jeffrey Joseph Robble (Natick, Massachusetts); Charles Borromeo Dunn (Hudson, New Hampshire)
ABSTRACT	Disclosed herein are system, apparatus, article of manufacture, method and/or computer program product embodiments for detection of satellite system anomalies. An embodiment operates by receiving satellite signals from a plurality of sources via at least one satellite system receiver and determining the presence of anomalous satellite system activity by comparing an amount of signal strength drop of each of the satellite signals during a time period to a threat detection threshold and by comparing an amount of consistency of the satellite signals during the time period to the threat detection threshold.
FILED	Monday, August 03, 2015
APPL NO	14/816488
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/20 (20130101) G01S 19/21 (20130101) G01S 19/215 (20130101) Original (OR) Class Secret Communication; Jamming of Communication H04K 3/90 (20130101)
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10281646 — Etchless acoustic waveguiding in integrated acousto-optic waveguides

US 10281646	Puckett et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S)	Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S)	Matthew Wade Puckett (Scottsdale, Arizona); Jianfeng Wu (Tucson, Arizona); Mary Salit (Plymouth, Minnesota); Tiequn Qiu (Glendale, Arizona)
ABSTRACT	An acousto-optic waveguide device comprises a substrate comprising a first material having a first refractive index and a first acoustic velocity; a cladding layer over the substrate, the cladding layer comprising a second material having a second refractive index that is distinct from the first refractive index, the second material having a second acoustic velocity that is distinct from the first acoustic velocity; and an optical core surrounded by the cladding layer, the optical core comprising a third material having a third refractive index that is higher that the first refractive index and the second refractive index, the third material having a third acoustic velocity that is distinct from the first acoustic velocity and the second acoustic velocity. The cladding layer that surrounds the optical core has a thickness configured to substantially confine acoustic waves to the cladding layer when an optical signal propagates through the optical core.
FILED	Wednesday, May 10, 2017
APPL NO	15/591836
ART UNIT	2883 — Optics
CURRENT CPC	Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/722 (20130101) Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/125 (20130101) G02F 1/353 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/20 (20130101)
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10281648 — Device support structures from bulk substrates

US 10281648	Burek et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S)	Michael J. Burek (Somerville, Massachusetts); Marko Loncar (Cambridge, Massachusetts)
ABSTRACT	A substrate is composed of a first material. A photonic structure is composed of the first material connected to one or more support structures composed of the first material between the photonic structure and a surface of the substrate, with at least one of the support structures supporting a first section of a strip of the photonic structure. The first section has a width that is wider than a width of a second section of the strip and has a length that is at least about twice the width of the second section of the strip.
FILED	Tuesday, July 30, 2013
APPL NO	13/954108
ART UNIT	2883 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/136 (20130101) Original (OR) Class G02B 6/1223 (20130101) G02B 2006/1204 (20130101) G02B 2006/12078 (20130101) G02B 2006/12107 (20130101) G02B 2006/12173 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24479 (20150115)
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10281746 — Wavelength-tunable III-V/Si hybrid optical transmitter

US 10281746	Zheng et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Oracle International Corporation (Redwood Shores, California)
ASSIGNEE(S)	Oracle International Corporation (Redwood Shores, California)
INVENTOR(S)	Xuezhe Zheng (San Diego, California); Ying Luo (San Diego, California); Jin Yao (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California)
ABSTRACT	An optical transmitter includes a reflective semiconductor optical amplifier (RSOA) coupled to an input end of a first optical waveguide. An end of the first optical waveguide provides a transmitter output for the optical transmitter. Moreover, a section of the first optical waveguide between the input end and the output end is optically coupled to a ring modulator that modulates an optical signal based on an electrical input signal. A passive ring filter (or a 1×N silicon-photonic switch and a bank of band reflectors) is connected to provide a mirror that reflects light received from the second optical waveguide back toward the RSOA to form a lasing cavity. Moreover, the ring modulator and the passive ring filter have different sizes, which causes a Vernier effect that provides a large wavelength tuning range for the lasing cavity in response to tuning the ring modulator and the passive ring filter.
FILED	Wednesday, September 05, 2018
APPL NO	16/122571
ART UNIT	2883 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/2808 (20130101) G02B 6/4286 (20130101) G02B 6/12004 (20130101) G02B 6/29338 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/011 (20130101) Original (OR) Class G02F 2203/15 (20130101) G02F 2203/70 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/50 (20130101) H01S 5/125 (20130101) H01S 5/0612 (20130101) H01S 5/1071 (20130101) H01S 5/3013 (20130101)
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10282066 — Dynamic threshold filtering for watched questions

US 10282066	Beller et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Charles E. Beller (Baltimore, Maryland); Paul J. Chase, Jr. (Fairfax, Virginia); Richard L. Darden (Leesburg, Virginia); Michael Drzewucki (Woodbridge, Virginia); Edward G. Katz (Washington, District of Columbia); Christopher Phipps (Arlington, Virginia)
ABSTRACT	Embodiments are directed to a watched questions threshold filtering system that functions to determine and deliver to a user relevant and significant data changes with respect to a user's goals, as defined by a notification threshold value provided by the user. The user is provided with an option to flag one or more queries for automatic re-querying. Confidence scores are processed on new data (i.e., data ingested after the original question was asked) by utilizing a confidence threshold for indicating if the new data warrants alerting a user.
FILED	Friday, July 08, 2016
APPL NO	15/205075
ART UNIT	2162 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 3/0481 (20130101) G06F 3/0484 (20130101) Original (OR) Class G06F 17/30654 (20130101) G06F 17/30699 (20130101)
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10282376 — Semi-structured spatial data conversion

US 10282376	Roe
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Marvin W. Roe (Slidell, Louisiana)
ABSTRACT	Embodiments relate to converting semi-structured spatial data. Initially, semi-structured spatial data is recursively traversed to determine a dynamically nested structure. The dynamically nested structure is translated into an application specific layer structure based on feature type grouping and display capabilities of a geographic information system (GIS) application. Next, an input symbology is determined for each feature in the semi-structured spatial data. The input symbology of each feature is analyzed to determine an application symbology for each map layer in the GIS application. A spatial database is created for the GIS application based on the application specific layer structure. The features are translated from the semi-structured spatial data into the spatial database, and the application symbology of each map layer is used to render the features in the GIS application.
FILED	Thursday, November 10, 2016
APPL NO	15/348605
ART UNIT	2168 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 16/88 (20190101) Original (OR) Class
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10282407 — Method for filtering data to generate a balance sheet

US 10282407	Lee
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Gilbert F. Lee (Greenbelt, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Gilbert F. Lee (Greenbelt, Maryland)
ABSTRACT	According to exemplary inventive embodiments, a computer spreadsheet program (e.g., Excel) is used to devise a balance sheet template and to import a financial report. The balance sheet template is a tabular presentation having headings designating network numbers, activity numbers, and various types of financial data. Network and activity numbers are enumerated on the balance sheet template, each network number being sub-categorized into one or more activity numbers. The balance sheet template is designed for entry, in blank spaces, of the designated types of financial data corresponding to pairings of enumerated network and activity numbers. A data-filtering macro (e.g., programmed in Visual Basic for Applications) identifies in the financial report, and inserts into the balance sheet template, every item of financial data that is pertinent to both (i) a designated type of financial data and (ii) a pairing of enumerated network and activity numbers.
FILED	Wednesday, August 21, 2013
APPL NO	13/972543
ART UNIT	2178 — Graphical User Interface and Document Processing
CURRENT CPC	Electric Digital Data Processing G06F 17/246 (20130101) Original (OR) Class
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10282537 — Single prompt multiple-response user authentication method

US 10282537	Swart et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Air Force Research Laboratory (AFRL)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Calvin B. Swart (Poughkeepsie, New York); Sharon M. Trewin (Croton-on-Hudson, New York)
ABSTRACT	A request for authentication from a user of a computer system is received. An authentication prompt is transmitted to the user, wherein the authentication prompt corresponds to a plurality of stored authentication responses, and wherein each of the plurality of stored authentication responses is used to authenticate the user. A first user authentication response is received. Whether to accept the first user authentication response based on a degree of similarity between the first user authentication response is determined and a stored authentication response from the plurality of stored authentication responses. Responsive to accepting the first user authentication response, a security score is calculated representing a level of confidence with respect to verifying the user for authentication, based on a type of authentication response for the first user authentication response. Responsive to determining that the security score is greater than an authentication score the user is authenticated.
FILED	Tuesday, September 20, 2016
APPL NO	15/270096
ART UNIT	3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Electric Digital Data Processing G06F 21/31 (20130101) G06F 21/32 (20130101) G06F 21/36 (20130101) G06F 21/40 (20130101) Original (OR) Class G06F 21/316 (20130101) G06F 21/6218 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) H04L 63/10 (20130101) H04L 63/102 (20130101)
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10282630 — Multi-channel compressive sensing-based object recognition

US 10282630	Kadambe et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	RAYTHEON COMPANY (Waltham, Massachusetts)
ASSIGNEE(S)	RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S)	Shubha Kadambe (Thousand Oaks, California); Kalin Spariosu, Jr. (Thousand Oaks, California); Juan C. Sotelo (Redondo Beach, California)
ABSTRACT	An optical system for capturing an image using compressive sensing includes: a digital micromirror device (DMD) array; an optical lens system; a first optical detector array; a first optical channel for projecting spatial information onto the first detector array; a second optical detector array; a second optical channel; a spectral filter and a polarization filter for projecting spectral and polarization information onto the second detector array; and an image processor to control the DMD array to generate a first and a second set of samples of the image using a sampling rate lower than required by the Shannon-Nyquist sampling theorem, and to reconstruct the image from the samples collected and digitized by the first and second optical detector arrays.
FILED	Wednesday, March 08, 2017
APPL NO	15/453669
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 26/0833 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/20 (20130101) G06K 9/741 (20130101) G06K 9/3241 (20130101) Original (OR) Class G06K 2009/4695 (20130101) Coding; Decoding; Code Conversion in General H03M 7/3062 (20130101) Pictorial Communication, e.g Television H04N 5/919 (20130101) H04N 5/7458 (20130101)
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10282636 — System, method, and recording medium for efficient cohesive subgraph identification in entity collections for inlier and outlier detection

US 10282636	Cheng et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Yu Cheng (Ossining, New York); Sharathchandra U. Pankanti (Darien, Connecticut); Nalini K. Ratha (White Plains, New York)
ABSTRACT	A similarity detection system receiving a plurality of input entities, the system including a cohesive subgraph identification device configured to calculate, based on attributes of the plurality of input entities, a first parameter and a second parameter based on the first parameter, and further configured to identify a plurality of subgraphs from the second parameter and a subgraph correlation tracking and clustering device configured to determine a relationship between different subgraphs based on a similarity factor between the second parameter and the plurality of subgraphs.
FILED	Tuesday, October 24, 2017
APPL NO	15/791662
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00228 (20130101) G06K 9/00442 (20130101) G06K 9/00677 (20130101) G06K 9/6215 (20130101) Original (OR) Class G06K 9/6218 (20130101) G06K 9/6296 (20130101)
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10282658 — Hardware architecture for simulating a neural network of neurons

US 10282658	Alvarez-Icaza Rivera et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Rodrigo Alvarez-Icaza Rivera (San Jose, California); John V. Arthur (Mountain View, California); Andrew S. Cassidy (San Jose, California); Pallab Datta (San Jose, California); Paul A. Merolla (Palo Alto, California); Dharmendra S. Modha (San Jose, California)
ABSTRACT	Embodiments of the invention relate to a neural network system for simulating neurons of a neural model. One embodiment comprises a memory device that maintains neuronal states for multiple neurons, a lookup table that maintains state transition information for multiple neuronal states, and a controller unit that manages the memory device. The controller unit updates a neuronal state for each neuron based on incoming spike events targeting said neuron and state transition information corresponding to said neuronal state.
FILED	Wednesday, August 17, 2016
APPL NO	15/239642
ART UNIT	2122 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/06 (20130101) G06N 3/08 (20130101) G06N 3/049 (20130101) G06N 3/063 (20130101) Original (OR) Class G06N 3/0635 (20130101)
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10282661 — Multi-modal neural network for universal, online learning

US 10282661	Modha
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Dharmendra S. Modha (San Jose, California)
ABSTRACT	In one embodiment, the present invention provides a neural network comprising multiple modalities. Each modality comprises multiple neurons. The neural network further comprises an interconnection lattice for cross-associating signaling between the neurons in different modalities. The interconnection lattice includes a plurality of perception neuron populations along a number of bottom-up signaling pathways, and a plurality of action neuron populations along a number of top-down signaling pathways. Each perception neuron along a bottom-up signaling pathway has a corresponding action neuron along a reciprocal top-down signaling pathway. An input neuron population configured to receive sensory input drives perception neurons along a number of bottom-up signaling pathways. A first set of perception neurons along bottom-up signaling pathways drive a first set of action neurons along top-down signaling pathways. Action neurons along a number of top-down signaling pathways drive an output neuron population configured to generate motor output.
FILED	Friday, March 10, 2017
APPL NO	15/456429
ART UNIT	2122 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) G06N 3/04 (20130101) G06N 3/08 (20130101) Original (OR) Class
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10282833 — Gate-level mapping of integrated circuits using multi-spectral imaging

US 10282833	Adato et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Science Foundation (NSF)
APPLICANT(S)	Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S)	Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S)	Ronen Adato (Boston, Massachusetts); Ajay Joshi (Lexington, Massachusetts); M. Selim Unlu (Newton, Massachusetts); Bennett B. Goldberg (Chicago, Illinois)
ABSTRACT	Optical verification testing of an IC includes obtaining images of the IC by, for each image: (i) illuminating the IC with excitation light, wherein the excitation light corresponds to a respective specific optical excitation of a predefined spectrum of optical excitations (e.g., wavelength spectrum); and (ii) detecting scattered light from the IC in response to the specific optical excitation. For each of a set of sub-regions of the images, the respective sub-region is mapped to at least one of (i) a specific sub-unit of a predefined set of sub-units (e.g., gates) of the IC and (ii) a null result, thereby creating a representation of a detected layout of the IC as an arrangement of the sub-units. The representation can be used to verify that an as-fabricated layout is consistent with an as-designed layout, to detect unauthorized modifications of the IC structure.
FILED	Wednesday, November 30, 2016
APPL NO	15/771493
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) G01N 21/956 (20130101) Electric Digital Data Processing G06F 17/5081 (20130101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) G06T 7/0004 (20130101) G06T 7/0006 (20130101) Original (OR) Class G06T 2207/10152 (20130101) G06T 2207/20021 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30148 (20130101)
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10282849 — Systems and methods for predictive/reconstructive visual object tracker

US 10282849	Piekniewski et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Brain Corporation (San Diego, California)
ASSIGNEE(S)	Brain Corporation (San Diego, California)
INVENTOR(S)	Filip Piekniewski (San Diego, California); Micah Richert (San Diego, California); Dimitry Fisher (San Diego, California); Patryk Laurent (San Diego, California); Csaba Petre (San Diego, California)
ABSTRACT	Systems and methods for predictive/reconstructive visual object tracking are disclosed. The visual object tracking has advanced abilities to track objects in scenes, which can have a variety of applications as discussed in this disclosure. In some exemplary implementations, a visual system can comprise a plurality of associative memory units, wherein each associative memory unit has a plurality of layers. The associative memory units can be communicatively coupled to each other in a hierarchical structure, wherein data in associative memory units in higher levels of the hierarchical structure are more abstract than lower associative memory units. The associative memory units can communicate to one another supplying contextual data.
FILED	Monday, June 19, 2017
APPL NO	15/627096
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Electric Digital Data Processing G06F 12/08 (20130101) G06F 2212/401 (20130101) G06F 2212/1016 (20130101) Image Data Processing or Generation, in General G06T 1/60 (20130101) G06T 7/0002 (20130101) G06T 7/20 (20130101) Original (OR) Class G06T 9/002 (20130101) G06T 9/004 (20130101) G06T 2207/20084 (20130101)
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10282850 — Method and implementation to detect coordinated motions of multiple entities

US 10282850	Wroblewski
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Ronald J. Wroblewski (San Diego, California)
ABSTRACT	A system is provided for determining coordinated motion between objects. The system includes a velocity data receiving component, a position data receiving component, a multidimensional indexing component and a determining component. The velocity data receiving component receives velocity data of the objects. The position data receiving component receives position data of the objects. The multidimensional indexing component generates multidimensional indices of the objects based on the velocity data and position data. The determining component determines whether there is coordinated motion between objects based on the multidimensional indices.
FILED	Thursday, April 20, 2017
APPL NO	15/492769
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Electric Digital Data Processing G06F 16/2264 (20190101) Image Data Processing or Generation, in General G06T 7/231 (20170101) Original (OR) Class G06T 2207/10044 (20130101) G06T 2207/20021 (20130101) G06T 2207/20072 (20130101) G06T 2207/30248 (20130101)
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10282925 — Adaptive algorithm-based engine health prediction

US 10282925	Steinert
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	Bell Helicopter Textron Inc. (Fort Worth, Texas)
ASSIGNEE(S)	Bell Helicopter Textron Inc. (Fort Worth, Texas)
INVENTOR(S)	Alan H. Steinert (Fort Worth, Texas)
ABSTRACT	A system and algorithm-based method of determining engine health and assuring available propulsion power based on historical data reflecting the individual engine's unique performance “fingerprint.”
FILED	Wednesday, October 05, 2016
APPL NO	15/286209
ART UNIT	3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 45/00 (20130101) B64D 2045/0085 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 23/0221 (20130101) G05B 23/0243 (20130101) Electric Digital Data Processing G06F 7/08 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/008 (20130101) G07C 5/085 (20130101) Original (OR) Class G07C 5/0808 (20130101) G07C 5/0816 (20130101)
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10283241 — Responsive cryogenic power distribution system

US 10283241	Kephart et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Jacob T. Kephart (Garnet Valley, Pennsylvania); Brian K. Fitzpatrick (Williamstown, New Jersey); Nathan N. Spivey (Swarthmore, Pennsylvania)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jacob T. Kephart (Garnet Valley, Pennsylvania); Brian K. Fitzpatrick (Williamstown, New Jersey); Nathan N. Spivey (Swarthmore, Pennsylvania)
ABSTRACT	A responsive cryogenic power distribution system for maintaining cryogenic refrigeration throughout a superconducting network. The responsive cryogenic power distribution system includes a plurality of cryogenic cable arrangements and cryogenic cooling stations, arranged to form a single master closed loop arrangement and a plurality of sub closed loop arrangements, enclosed within the single master closed loop arrangement. The system also includes sensors and controllers that allow for reconfiguration in the event of a loss of one or more cryogenic cooling stations and/or one or more cryogenic cable arrangements.
FILED	Tuesday, May 15, 2012
APPL NO	13/471654
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 3/085 (20130101) F17C 2270/0527 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/14 (20130101) Original (OR) Class
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10283354 — Methods of growing thin films at low temperatures using electron stimulated desorption (ESD)

US 10283354	George et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S)	Steven M. George (Boulder, Colorado); Andrew S. Cavanagh (Boulder, Colorado)
ABSTRACT	The invention includes a method of promoting thin film growth on a solid substrate, wherein derivatization of the substrate comprises formation of at least one surface species. In certain embodiments, the method comprises desorbing the surface species from the substrate using electron stimulated desorption (ESD).
FILED	Monday, September 22, 2014
APPL NO	15/024269
ART UNIT	2895 — Semiconductors/Memory
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/303 (20130101) C23C 16/345 (20130101) C23C 16/402 (20130101) C23C 16/4554 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0217 (20130101) H01L 21/0228 (20130101) H01L 21/0254 (20130101) H01L 21/0259 (20130101) H01L 21/0262 (20130101) H01L 21/02164 (20130101) H01L 21/02266 (20130101) H01L 21/02381 (20130101) Original (OR) Class H01L 21/02532 (20130101) H01L 21/02631 (20130101)
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10283459 — Vanishing via for hardware IP protection from reverse engineering

US 10283459	Bhunia et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S)	Swarup Bhunia (Gainesville, Florida); Haoting Shen (Tallahassee, Florida); Mark M. Tehranipoor (Gainesville, Florida); Domenic J. Forte (Gainesville, Florida); Navid Asadizanjani (Gainesville, Florida)
ABSTRACT	A semiconductor device can include a first metal trace, a first via disposed on the first metal trace, a second metal trace disposed on the first via, and an insulator interposed between the first metal trace and the first via. The insulator can be configured to lower an energy barrier or redistribute structure defects or charge carriers, such that the first metal trace and the first via are electrically connected to each other when power is applied. The semiconductor device can further include a dummy via disposed on the first metal trace.
FILED	Friday, January 05, 2018
APPL NO	15/863133
ART UNIT	2816 — Semiconductors/Memory
CURRENT CPC	Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/0012 (20130101) B81B 2201/01 (20130101) B81B 2201/014 (20130101) B81B 2201/018 (20130101) B81B 2207/07 (20130101) Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 29/02 (20130101) H01H 59/0009 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/525 (20130101) H01L 23/528 (20130101) H01L 23/573 (20130101) Original (OR) Class H01L 23/5228 (20130101) H01L 23/5252 (20130101) H01L 23/53238 (20130101)
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10283561 — Two-terminal spintronic devices

US 10283561	Wang et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S)	Jian-Ping Wang (Shoreview, Minnesota); Yang Lv (New Brighton, Minnesota); Mahdi Jamali (Folsom, California)
ABSTRACT	This disclosure describes an example device that includes a first contact line, a second contact line, a spin-orbital coupling channel, and a magnet. The spin-orbital coupling channel is coupled to, and is positioned between, the first contact line and second contact line. The magnet is coupled to the spin-orbital coupling channel and positioned between the first contact line and the second contact line. A resistance of the magnet and spin-orbital coupling channel is a unidirectional magnetoresistance.
FILED	Tuesday, December 12, 2017
APPL NO	15/839081
ART UNIT	2825 — Semiconductors/Memory
CURRENT CPC	Static Stores G11C 11/16 (20130101) G11C 11/18 (20130101) G11C 11/161 (20130101) G11C 11/1675 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/22 (20130101) H01L 27/224 (20130101) Original (OR) Class H01L 43/04 (20130101) Pulse Technique H03K 19/18 (20130101) H03K 19/177 (20130101) H03K 19/1776 (20130101)
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10283597 — Scandium-containing III-N etch-stop layers for selective etching of III-nitrides and related materials

US 10283597	Hardy et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Matthew T. Hardy (Arlington, Virginia); Brian P. Downey (Alexandria, Virginia); David J. Meyer (Fairfax, Virginia)
ABSTRACT	A semiconductor device structure including a scandium (Sc)- or yttrium (Y)-containing material layer situated between a substrate and one or more overlying layers. The Sc- or Y-containing material layer serves as an etch-stop during fabrication of one or more devices from overlying layers situated above the Sc- or Y-containing material layer. The Sc- or Y-containing material layer can be grown within an epitaxial group III-nitride device structure for applications such as electronics, optoelectronics, and acoustoelectronics, and can improve the etch-depth accuracy, reproducibility and uniformity.
FILED	Thursday, November 09, 2017
APPL NO	15/807821
ART UNIT	2819 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/02378 (20130101) H01L 21/02439 (20130101) H01L 21/02458 (20130101) H01L 21/02502 (20130101) H01L 21/3065 (20130101) H01L 21/3081 (20130101) H01L 29/201 (20130101) H01L 29/2003 (20130101) Original (OR) Class
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10283658 — Interband cascade devices

US 10283658	Yang
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S)	Rui Q. Yang (Norman, Oklahoma)
ABSTRACT	Photovoltaic (PV) and photodetector (PD) devices, comprising a plurality of interband cascade (IC) stages, wherein the IC stages comprise an absorption region with a type-I superlattice and/or a bulk semiconductor material having a band gap, the absorption region configured to absorb photons, an intraband transport region configured to act as a hole barrier, and an interband tunneling region configured to act as an electron barrier, wherein the absorption region, the intraband transport region, and the interband tunneling region are positioned such that electrons will flow from the absorption region to the intraband transport region to the interband tunneling region.
FILED	Monday, September 14, 2015
APPL NO	14/853588
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0304 (20130101) H01L 31/0725 (20130101) H01L 31/0735 (20130101) H01L 31/035236 (20130101) Original (OR) Class Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101)
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10283667 — Surface plasma wave coupled detectors

US 10283667	Brueck et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Steven R. J. Brueck (Albuquerque, New Mexico); Sanjay Krishna (Albuquerque, New Mexico); Seung-Chang Lee (Albuquerque, New Mexico)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Steven R. J. Brueck (Albuquerque, New Mexico); Sanjay Krishna (Albuquerque, New Mexico); Seung-Chang Lee (Albuquerque, New Mexico)
ABSTRACT	The present disclosure relates to an electromagnetic energy detector. The detector can include a substrate having a first refractive index; a metal layer; an absorber layer having a second refractive index and disposed between the substrate and the metal layer; a coupling structure to convert incident radiation to a surface plasma wave; additional conducting layers to provide for electrical contact to the electromagnetic energy detector, each conducting layer characterized by a conductivity and a refractive index; and a surface plasma wave (“SPW”) mode-confining layer having a third refractive index that is higher than the second refractive index disposed between the substrate and the metal layer.
FILED	Tuesday, September 06, 2016
APPL NO	15/257348
ART UNIT	2815 — Semiconductors/Memory
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) G02B 6/1226 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/105 (20130101) H01L 31/109 (20130101) H01L 31/184 (20130101) Original (OR) Class H01L 31/0304 (20130101) H01L 31/0336 (20130101) H01L 31/1844 (20130101) H01L 31/02327 (20130101) H01L 31/02363 (20130101) H01L 31/03046 (20130101) H01L 31/022408 (20130101) H01L 31/035218 (20130101) H01L 31/035236 (20130101)
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10283691 — Nano-composite thermo-electric energy converter and fabrication method thereof

US 10283691	Darwish et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Dillard University (New Orleans, Louisiana)
ASSIGNEE(S)	Dillard University (New Orleans, Louisiana)
INVENTOR(S)	Abdalla Darwish (Kenner, Louisiana); Sergey Sarkisov (Huntsville, Alabama); Paolo Mele (Muroran, Japan)
ABSTRACT	Briefly, the present disclosure relates to a nanocomposite thermoelectric energy converter comprising a composite thin film inorganic semiconductor having carbonized polymer nano-clusters and the net of polymer nano-fibers included within. The carbonized polymer nano-clusters and nano-fibers improve the thermoelectric figure of merit ZT by increasing electrical conductivity and decreasing thermal conductivity. The converter may be fabricated by a dual beam pulsed laser deposition process. A first laser beam evaporates a target comprising the materials of the inorganic semiconductor. A second laser beam evaporates the polymer using a matrix assisted target for depositing the polymer concurrently with the semiconductor deposition to yield the composite film. The lasers may be separately controlled to determine the resulting composition. The converter may be deposited on rigid or flexible substrates for a wide range of applications.
FILED	Monday, September 14, 2015
APPL NO	14/853674
ART UNIT	1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/02 (20130101) H01L 35/22 (20130101) Original (OR) Class H01L 35/34 (20130101)
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10283693 — Multiloop interferometers for quantum information processing

US 10283693	Kerman
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Andrew J. Kerman (Arlington, Massachusetts)
ABSTRACT	Structures and techniques, using superconducting Josephson-junction based circuits, to directly engineer physical multiqubit (or “many-qubit”) interactions in a non-perturbative manner. In one embodiment, a system for multiqubit interaction includes: a multispin coupler including a plurality of loops, each loop having a pair of Josephson junctions; and a plurality of qubits each inductively coupled to the multispin coupler.
FILED	Thursday, November 17, 2016
APPL NO	15/354275
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/025 (20130101) Original (OR) Class
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10283695 — Method for creating high-resolution micro- to nano-scale structures in high-temperature superconductor films

US 10283695	Taylor et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Benjamin J. Taylor (Escondido, California); Teresa H. Emery (San Diego, California)
ABSTRACT	A method includes providing a film of a high-temperature superconductor compound on a substrate, where a portion of the film has a first oxygen state, and exposing a portion of the film to a focused ion beam to create a structure within the film. The structure may result from the portion of the film being partially or completely removed. The structure may be a trench along the length or width of the film. The method may include annealing the exposed portion of the film to a second oxygen state. The oxygen content of the second oxygen state may be greater or less than the oxygen content of the first oxygen state.
FILED	Friday, July 01, 2016
APPL NO	15/200674
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/025 (20130101) H01L 39/126 (20130101) H01L 39/225 (20130101) H01L 39/249 (20130101) Original (OR) Class H01L 39/2464 (20130101) H01L 39/2496 (20130101)
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10283696 — Architecture for coupling quantum bits using localized resonators

US 10283696	Dial et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Office of the Director of National Intelligence (ODNI) Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Oliver Dial (Yorktown Heights, New York); Jay M. Gambetta (Yorktown Heights, New York); Douglas T. McClure, III (Rye, New York); Matthias Steffen (Cortlandt Manor, New York)
ABSTRACT	A technique relates a superconducting microwave cavity. An array of posts has different heights in the cavity, and the array supports a localized microwave mode. The array of posts includes lower resonant frequency posts and higher resonant frequency posts. The higher resonant frequency posts are arranged around the lower resonant frequency posts. A first plate is opposite a second plate in the cavity. One end of the lower resonant frequency posts is positioned on the second plate so as to be electrically connected to the second plate. Another end of the lower resonant frequency posts in the array is open so as not to form an electrical connection to the first plate. Qubits are connected to the lower resonant frequency posts in the array of posts, such that each of the qubits is physically connected to one or two of the lower resonant frequency posts in the array of posts.
FILED	Monday, November 23, 2015
APPL NO	14/949248
ART UNIT	2827 — Semiconductors/Memory
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/14 (20130101) H01L 39/025 (20130101) H01L 39/2493 (20130101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/205 (20130101) H01P 7/00 (20130101)
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10283851 — Broadband circularly polarized antenna incorporating non-Foster active loading

US 10283851	Church et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	SPAWAR Systems Center Pacific (San Diego, California)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Justin A. Church (San Diego, California); Nazia Ahmed Mozaffar (San Diego, California); Frederick J. Verd (Santee, California)
ABSTRACT	An antenna comprising: a solar collector; two conductive, orthogonal half-loops mounted to the solar collector such that the solar collector functions as a ground; an RF power source configured to feed RF power to each of the two half-loops having a 90-degree phase difference relative to each other; and a conductive cage structure surrounding the two half-loops, wherein the cage structure includes a conductive ring disposed above the center section, the conductive ring having an equilateral cross of conductive material disposed within the ring and supported by leg structures which are in electrically-conductive contact with the solar collector, and wherein each leg structure has attached thereto a non-Foster circuit having a negative impedance, wherein the non-Foster circuits are configured to actively load the cage structure such that the cage structure functions as an active, internal matching network for the antenna.
FILED	Tuesday, September 19, 2017
APPL NO	15/709182
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/50 (20130101) H01Q 1/288 (20130101) Original (OR) Class H01Q 15/24 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/40 (20141201) H02S 30/20 (20141201)
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10283868 — Tunable patch antenna

US 10283868	Breed
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	David S. Breed (Panama City, Florida)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	David S. Breed (Panama City, Florida)
ABSTRACT	A tunable patch antenna includes a dielectric substrate having first and second surfaces. An electrically-conductive sheet is coupled to the first surface, and a patch assembly is coupled to the second surface. The patch assembly includes an electrically-conductive base fixedly coupled to the second surface and an electrically-conductive disk rotatably coupled to the substrate. The base has a substantially circular void wherein a perimeter region of the base circumscribes the void. The base has an electrically-conductive run extending from the perimeter region to a feedpoint location within the void. The disk has a diameter greater than a diameter of the void such that the disk is in contact with the perimeter region of the base. The disk has a slot cut through it that is aligned with a center of the disk.
FILED	Tuesday, December 06, 2016
APPL NO	15/370092
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/36 (20130101) H01Q 1/38 (20130101) H01Q 1/42 (20130101) H01Q 1/48 (20130101) H01Q 1/243 (20130101) H01Q 9/04 (20130101) H01Q 9/0442 (20130101) Original (OR) Class H01Q 9/0485 (20130101)
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10283871 — Reconfigurable antenna array and associated method of use

US 10283871	Gong et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S)	Xun Gong (Oviedo, Florida); Mahmoud Shirazi (Orlando, Florida); Tianjiao Li (Apopka, Florida)
ABSTRACT	A reconfigurable antenna array capable of utilizing a common antenna aperture which can cover a wide frequency range in a continuous way. With the basic antenna element based on a slot-ring and using a self similar structure approach and RE' switches, the antenna array operates without grating lobes. The antenna array exhibits polarization diversity and single-side radiation capability. When varactors are implemented into the array, the antenna array can cover the frequency range by continuously tuning the center frequency with a relatively narrow instantaneous bandwidth.
FILED	Monday, October 09, 2017
APPL NO	15/728124
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/48 (20130101) H01Q 5/50 (20150115) H01Q 13/103 (20130101) Original (OR) Class H01Q 21/064 (20130101) Transmission H04B 7/10 (20130101)
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10283877 — Multipolarized vector sensor array antenna system for radio astronomy applications

US 10283877	Fenn et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute Of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute Of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Alan J. Fenn (Wayland, Massachusetts); Frank C. Robey (Concord, Massachusetts); Peter T. Hurst (Cambridge, Massachusetts); Mark J. Silver (Bedford, Massachusetts); Joseph M. D'Arco (Chelsea, Massachusetts)
ABSTRACT	The present invention generally relates to an electromagnetic field vector sensing receive antenna array system for installation and deployment on a structure. A multipolarized array of collocated antenna elements is used to provide calibrated amplitude and phase radiation patterns with monopole, dipole, and loop modes generated from crossed loops connected to a be beamformer. The invention has applications for installation and deployment on a tower, balloon, or satellite for radio frequency sensing and location of low-frequency galactic emissions. The novel receive antenna array system comprises a multipolarized vector sensor antenna array. The disclosed direction-finding vector sensor can be installed and deployed on a structure and can detect and locate radio frequency emissions from galactic sources. The key system components of the receive antenna array system consist of deployable antennas, receivers, signal processing computer, and communications link.
FILED	Wednesday, October 19, 2016
APPL NO	15/297220
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/18 (20130101) G01S 3/143 (20130101) Antennas, i.e Radio Aerials H01Q 1/14 (20130101) H01Q 1/288 (20130101) H01Q 5/48 (20150115) H01Q 7/02 (20130101) H01Q 7/005 (20130101) H01Q 21/24 (20130101) H01Q 21/29 (20130101) H01Q 21/245 (20130101) H01Q 25/04 (20130101) Original (OR) Class Transmission H04B 7/0617 (20130101) H04B 7/0885 (20130101)
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10284339 — Differential MIMO transceiver

US 10284339	Sayeed et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) National Science Foundation (NSF)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Akbar M. Sayeed (Madison, Wisconsin); John H. Brady (Madison, Wisconsin)
ABSTRACT	A receiver detects a plurality of information symbols. A first signal and a second signal are received from a first transmitted signal and a second transmitted signal, respectively, transmitted by a first plurality of antennas and received by a second plurality of antennas connected to the receiver. The second signal is received after the first signal. The receiver spatially filters the first signal using a spatial filter matrix. The receiver computes a conjugate of the first filtered signal to define a conjugate first signal, and spatially filters a second signal using the spatial filter matrix. The receiver computes a Hadamard product of the first filtered signal and the conjugate first signal to define a differential measurement signal. The receiver detects the plurality of information symbols from the differential measurement signal.
FILED	Monday, November 27, 2017
APPL NO	15/823018
ART UNIT	2631 — Digital Communications
CURRENT CPC	Transmission H04B 7/0413 (20130101) H04B 7/0617 (20130101) H04B 7/0626 (20130101) H04B 7/0697 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0618 (20130101) Original (OR) Class H04L 25/03 (20130101)
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10284402 — Direct RF demodulation

US 10284402	Valdes Garcia et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Alberto Valdes Garcia (Chappaqua, New York); Wayne H. Woods, Jr. (Burlington, Massachusetts); Bodhisatwa Sadhu (Fishkill, New York)
ABSTRACT	An apparatus for decoding a data modulated signal includes a signal receiver that receives a data modulated signal that is encoded with phase-shift keying (PSK) and provides an amplified signal corresponding to the data modulated signal, a tunable phase shifter that receives a local reference signal and a selected phase shift, applies the selected phase shift to the local reference signal to produce a phase shifted reference signal, a summing unit that sums the amplified signal and the phase shifted reference signal to produce a summed signal, an amplitude detector that determines an amplitude of the summed signal, and a symbol detector that varies the selected phase shift and determines a current symbol within the data modulated signal based on the amplitude of the summed signal as the selected phase shift is varied. A corresponding method is also disclosed herein.
FILED	Monday, June 04, 2018
APPL NO	15/996611
ART UNIT	2631 — Digital Communications
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 27/22 (20130101) Original (OR) Class
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10285190 — Scheduling access to a shared medium

US 10285190	Khoury et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts); Raytheon BBN Technologies Corp. (Cambridge, Massachusetts)
ASSIGNEE(S)	Raytheon BBN Technologies Corp. (Cambridge, Massachusetts); Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Joud Khoury (Boston, Massachusetts); Christopher Paul Vander Valk (West Chester, Ohio); Michael Brandon Kremer (Cambridge, Massachusetts); Subramanian Ramanathan (Westford, Massachusetts); Jeffery Jay Logan (Culver City, California); Charles Hansen (Palos Verdes Estates, California)
ABSTRACT	Generally discussed herein are systems, devices, and methods for scheduling node performance of communication and/or function. A method can include receiving, from a plurality of nodes, parameters indicating a trajectory and position of each of the plurality of nodes, creating a directed communication graph, creating a communications conflict graph, creating a function conflict graph indicating which function performed by one node of the plurality of nodes interferes with at least one of a function and communication performed by another node of the plurality of nodes, creating a universal conflict graph based on the communications conflict graph and the function conflict graph, creating a schedule for communication and function performance for each of the nodes based on the universal conflict graph, and providing data indicative of the schedule to nodes of the plurality of nodes.
FILED	Tuesday, December 20, 2016
APPL NO	15/385821
ART UNIT	2465 — Multiplex and VoIP
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/66 (20130101) Electric Digital Data Processing G06F 17/30958 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/006 (20130101) H04L 5/0016 (20130101) H04L 5/0073 (20130101) Wireless Communication Networks H04W 72/082 (20130101) H04W 72/121 (20130101) H04W 72/0453 (20130101) H04W 72/1263 (20130101) Original (OR) Class
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Department of Health and Human Services (HHS)

10278374 — Genetically modified mice and engraftment

US 10278374	Stevens et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Regeneron Pharmaceuticals, Inc. (Tarrytown, New York); Yale University (New Haven, Connecticut); Institute for Research in Biomedicine (IRB) (Bellinzona, Switzerland)
ASSIGNEE(S)	Regeneron Pharmaceuticals, Inc. (Tarrytown, New York); Yale University (New Haven, Connecticut); Institute for Research in Biomedicine (IRB) (Bellinzona, Switzerland)
INVENTOR(S)	Sean Stevens (Del Mar, California); Andrew J. Murphy (Croton-on-Hudson, New York); Richard Flavell (Guilford, Connecticut); Elizabeth Eynon (New Haven, Connecticut); Jorge Galan (New Haven, Connecticut); Tim Willinger (Ultran, Sweden); Markus Manz (Zollikon, Switzerland); Anthony Rongvaux (New Haven, Connecticut); George D. Yancopoulos (Yorktown Heights, New York)
ABSTRACT	A mouse with a humanization of the mIL-3 gene and the mGM-CSF gene, a knockout of a mRAG gene, and a knockout of a mll2rg subunit gene; and optionally a humanization of the TPO gene is described. A RAG/ll2rg KO/hTPO knock-in mouse is described. A mouse engrafted with human hematopoietic stem cells (HSCs) that maintains a human immune cell (HIC) population derived from the HSCs and that is infectable by a human pathogen, e.g., S. typhi or M. tuberculosis is described. A mouse that models a human pathogen infection that is poorly modeled in mice is described, e.g., a mouse that models a human mycobacterial infection, wherein the mouse develops one or more granulomas comprising human immune cells. A mouse that comprises a human hematopoietic malignancy that originates from an early human hematopoietic cells is described, e.g., a myeloid leukemia or a myeloproliferative neoplasia.
FILED	Tuesday, January 03, 2017
APPL NO	15/397628
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 67/0275 (20130101) A01K 67/0278 (20130101) Original (OR) Class A01K 2207/12 (20130101) A01K 2207/15 (20130101) A01K 2217/15 (20130101) A01K 2217/072 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) A01K 2267/0331 (20130101) A01K 2267/0337 (20130101) A01K 2267/0381 (20130101) A01K 2267/0387 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/00 (20130101) Peptides C07K 14/524 (20130101) C07K 14/535 (20130101) C07K 14/5403 (20130101) C07K 14/7155 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/00 (20130101)
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10278583 — Systems and methods for measuring cardiac strain

US 10278583	Kar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	WASHINGTON UNIVERSITY (St. Louis, Missouri)
ASSIGNEE(S)	Washington University (St. Louis, Missouri)
INVENTOR(S)	Julia Kar (St. Louis, Missouri); Michael K. Pasque (St. Louis, Missouri); Brian P. Cupps (St. Louis, Missouri)
ABSTRACT	A method for rapid computation of three-dimensional displacement and Lagrange strain in a high resolution filed of phase data obtained with Displacement Encoding with Stimulated Echoes (DENSE) in magnetic resonance images of the myocardium. The method includes semi-automated segmentation of a region of a heart, phase unwrapping the images in three dimensions, and a custom radial point interpolation method (RPIM). The RPIM is a meshfree numerical analysis method that uses radial basis functions and polynomial functions to calculate the Lagrange strain of DENSE displacement data acquired from the myocardium.
FILED	Thursday, October 22, 2015
APPL NO	15/520991
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0044 (20130101) Original (OR) Class A61B 5/055 (20130101) A61B 2576/023 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/5611 (20130101) G01R 33/56316 (20130101) G01R 33/56333 (20130101) Electric Digital Data Processing G06F 19/321 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 7/60 (20130101) G06T 2200/04 (20130101) G06T 2207/10088 (20130101) G06T 2207/30048 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101)
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10278637 — Accurate analysis tool and method for the quantitative acoustic assessment of infant cry

US 10278637	Sheinkopf et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	BROWN UNIVERSITY (Providence, Rhode Island); WOMEN and INFANTS HOSPITAL OF RHODE ISLAND (Providence, Rhode Island)
ASSIGNEE(S)	Brown University (Providence, Rhode Island); Women and Infants Hospital of Rhode Island (Providence, Rhode Island)
INVENTOR(S)	Stephen J. Sheinkopf (Barrington, Rhode Island); Barry M. Lester (Warwick, Rhode Island); Harvey F. Silverman (East Greenwich, Rhode Island)
ABSTRACT	An automated infant cry analyzer with high accuracy to detect important acoustic features of cry is provided. The system's accuracy was rigorously tested and was compared to ground truth manual coding. The resulting methods and systems are applied to infant developmental disorders.
FILED	Friday, February 27, 2015
APPL NO	14/633224
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/16 (20130101) A61B 5/121 (20130101) A61B 5/4076 (20130101) A61B 5/4803 (20130101) Original (OR) Class A61B 5/7257 (20130101) A61B 5/7275 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 17/26 (20130101) G10L 25/18 (20130101) G10L 25/66 (20130101) G10L 25/78 (20130101) G10L 25/90 (20130101) G10L 2025/906 (20130101)
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10278781 — Tool exchange interface and control algorithm for cooperative surgical robots

US 10278781	Taylor et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The John Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Russell H. Taylor (Severna Park, Maryland); Marcin Arkadiusz Balicki (Baltimore, Maryland); James Tahara Handa (Baltimore, Maryland)
ABSTRACT	A system and method for tool exchange during surgery for cooperatively controlled robots comprises a tool holder for receiving a surgical tool adapted to be held by a robot and a surgeon, a tool holding element for constraining downward motion of the tool while allowing low force removal of the surgical tool from the holder, a first sensor for detecting if the surgical tool is docked within the tool holder, and a selector for automatically selecting different movements or actions of the tool holder to be performed based upon information detected by the first sensor. The system and method of the present invention provides an advantage to an often slow moving cooperative robot, by increasing the speed by which the tool holder may move in the direction away from the patient.
FILED	Monday, December 19, 2016
APPL NO	15/383931
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 34/30 (20160201) A61B 34/32 (20160201) Original (OR) Class A61B 90/06 (20160201) A61B 2017/00477 (20130101) A61B 2090/064 (20160201) A61B 2090/065 (20160201) A61B 2090/0811 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 15/0466 (20130101)
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10278836 — Self-aligning prosthesis with hydraulic actuators

US 10278836	Boone et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	OTTO BOCK HEALTHCARE GMBH (Duderstadt, Germany)
ASSIGNEE(S)	OTTOBOCK SE and CO. KGAA (Duderstadt, Germany)
INVENTOR(S)	David Alan Boone (Seattle, Washington); Ben Gilbert Macomber (Shoreline, Washington); Lonnie Love (Oak Ridge, Tennessee)
ABSTRACT	A hydraulic device includes a first plate that pivots in a first direction, a second plate that pivots in a second direction orthogonal to the first direction, a first hydraulic system comprising a first cylinder and piston, a second cylinder and piston and, channels connecting the first cylinder to the second cylinder, the first hydraulic system filled with hydraulic fluid, wherein the transfer of fluid between the first cylinder and second cylinder pivots the first plate, and a second hydraulic system comprising a third cylinder and piston, a fourth cylinder and piston and, channels connecting the third cylinder to the fourth cylinder, the second hydraulic system filled with hydraulic fluid, wherein the transfer of fluid between the third cylinder and fourth cylinder pivots the second plate.
FILED	Thursday, May 02, 2013
APPL NO	13/886100
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/60 (20130101) A61F 2/68 (20130101) Original (OR) Class A61F 2/76 (20130101) A61F 2002/704 (20130101) A61F 2002/745 (20130101) A61F 2002/748 (20130101) A61F 2002/5018 (20130101) A61F 2002/5023 (20130101) A61F 2002/7625 (20130101) A61F 2002/7635 (20130101) A61F 2002/7645 (20130101) A61F 2002/7655 (20130101)
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10278859 — Image-guided delivery of ophthalmic therapeutics

US 10278859	Srivastava et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
ASSIGNEE(S)	THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
INVENTOR(S)	Sunil K. Srivastava (Shaker Heights, Ohio); Justis P. Ehlers (Shaker Hts., Ohio); Yuankai K. Tao (Shaker Hts., Ohio)
ABSTRACT	Systems and methods are provided for image-guided delivery of therapeutics to an eye. An optical coherence tomography (OCT) imager is configured to produce at least one OCT image of the eye. A therapeutic delivery system is configured to deliver a therapeutic to the eye through a distal end of a delivery mechanism. A system control is configured to determine a position of the distal end of the delivery mechanism and control the therapeutic delivery system according to at least the determined position.
FILED	Monday, October 19, 2015
APPL NO	14/886428
ART UNIT	3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/102 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Original (OR) Class A61F 9/0026 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101)
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10278929 — Identification of stabilizers of multimeric proteins

US 10278929	Graef et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Isabella A. Graef (Woodside, California); Mamoun M. Alhamadsheh (Fremont, California)
ABSTRACT	Disclosed herein are compounds and compositions thereof which find use in increasing stability of TTR tetramers reducing its tendency to misfold and form aggregates. Also provided herein are methods for using these compounds and compositions for increasing stability of TTR and thereby decreasing aggegate formation by TTR. Also disclosed herein are methods to screen for candidate compounds that increase stability of TTR. Also disclosed herein are heterobifunctional compounds that include a TTR binding compound connected to a targeting moiety via a linker, for use in disrupting PPis of a target protein.
FILED	Monday, March 26, 2018
APPL NO	15/936159
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) Original (OR) Class A61K 31/166 (20130101) A61K 31/428 (20130101) A61K 31/433 (20130101) A61K 31/519 (20130101) A61K 31/4196 (20130101) Heterocyclic Compounds C07D 231/12 (20130101) C07D 487/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101)
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10278982 — Method of treating heterotopic ossification

US 10278982	Levi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Benjamin Levi (Ann Arbor, Michigan); Shailesh Agarwal (Ypsilanti, Michigan)
ABSTRACT	The invention provides a method of treating heterotopic ossification in a subject in need thereof. The method comprises administering a hypoxia inducible factor-1α (Hif-1α) inhibitor to the subject. In various embodiments, the Hif-1α inhibitor is PX-478, rapamycin, or digoxin.
FILED	Friday, December 09, 2016
APPL NO	15/373959
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) A61K 31/436 (20130101) A61K 31/7048 (20130101) Original (OR) Class
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10278990 — Methods for promoting hematopoietic reconstitution

US 10278990	Zon et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S)	Children's Medical Center Corporation (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Leonard I. Zon (Wellesley, Massachusetts); Trista E. North (Newton Center, Massachusetts); Wolfram Goessling (Chestnut Hill, Massachusetts)
ABSTRACT	The present invention provides for compositions and methods for modulating hematopoetic stem cell populations by using HCS modulators, which are agents that either increase HSC numbers or decrease HSC numbers as desired by a particular indication. For example, HSC modulators found to increase HSC numbers include prostaglandin E₂(PGE2) and agents that stimulate the PGE2 pathway. Conversely, HSC modulators that prevent PGE2 synthesis decrease HSC numbers. HCS modulators may be used in vitro, in vivo, or ex vivo.
FILED	Friday, March 15, 2013
APPL NO	13/836794
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) A61K 35/14 (20130101) Original (OR) Class A61K 35/28 (20130101) A61K 35/50 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 2501/02 (20130101)
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10279009 — Histone deacetylase (HDAC) inhibitor up-regulates car expression and targeted antigen intensity, increasing antitumor efficacy

US 10279009	Vera Valdes et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Baylor College of Medicine (Houston, Texas)
ASSIGNEE(S)	Baylor College of Medicine (Houston, Texas)
INVENTOR(S)	Juan Fernando Vera Valdes (Bellaire, Texas); Malcolm Brenner (Bellaire, Texas); Usanarat Anurathapan (Houston, Texas)
ABSTRACT	Embodiments of the invention employ methods and compositions for enhancing potency of immune cells that express one or more therapeutic proteins. In certain cases, the methods modulate expression of a CAR transgene in an immune cell, such as a T cell. Specific embodiments employ the exposure of cells and/or individuals to be treated with the cells with an effective amount of at least one agent that upregulates expression of the therapeutic protein, such as a mitogen, histone deacetylase inhibitor, and or DNA methyltransferase inhibitor.
FILED	Friday, July 18, 2014
APPL NO	14/335766
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/706 (20130101) A61K 31/706 (20130101) A61K 35/17 (20130101) A61K 38/164 (20130101) A61K 38/177 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) C12N 2501/06 (20130101) C12N 2501/065 (20130101) C12N 2510/00 (20130101)
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10279011 — Methods of use for IL-22 promoting rejuvenation of thymic and bone marrow function

US 10279011	Dudakov et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S)	MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
INVENTOR(S)	Jarrod Dudakov (New York, New York); Marcel van den Brink (New York, New York); Alan Hanash (New York, New York)
ABSTRACT	The present invention provides methods and compositions for the use of IL-22 to promote thymic growth following thymic insult. In particularly preferred embodiments, the present invention provides methods of using therapeutic IL-22 compositions for treating patients with thymic atrophy and alterations in bone marrow derived white blood cells, including cancer patients undergoing chemotherapy, patients exposed to radiation (i.e. cancer therapy, nuclear disaster, terrorist attack, etc.), patients with HIV infections/AIDS, patients with organ transplantation, aging patients, and the like. In a further embodiment, therapeutic IL-22 compositions are contemplated as a prophylactic to boost immune response when additional T-cell function is needed, i.e. to boost immune response during vaccination.
FILED	Monday, June 15, 2015
APPL NO	14/739743
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/20 (20130101) Original (OR) Class
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10279019 — PCSK9 peptide vaccine conjugated to a Qbeta carrier and methods of using the same

US 10279019	Remaley et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia); STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Alan Remaley (Bethesda, Maryland); John T. Schiller (Kensington, Maryland); Marcelo Amar (Gaithersburg, Maryland); Bryce Chackerian (Albuquerque, New Mexico)
ABSTRACT	A vaccine construct comprising an antigenic PCSK9 peptide and an immunogenic carrier, and methods of using the same that are effective to lower blood cholesterol levels in a mammal and treat dyslipidemias and related disease states in a mammal without the frequency of administration required by passive immunity strategies.
FILED	Wednesday, February 11, 2015
APPL NO	15/118143
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/10 (20130101) A61K 39/0005 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/6901 (20170801) A61K 2039/60 (20130101) A61K 2039/627 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Peptides C07K 11/00 (20130101) C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6454 (20130101) C12N 2795/18123 (20130101) C12N 2795/18134 (20130101) C12N 2795/18141 (20130101) Enzymes C12Y 304/21061 (20130101)
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10279020 — Tumor vaccine

US 10279020	Podack
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	University of Miami (Miami, Florida)
ASSIGNEE(S)	University of Miami (Miami, Florida)
INVENTOR(S)	Eckhard R. Podack (Coconut Grove, Florida)
ABSTRACT	The invention relates to the fields of medicine, immunology, and oncology. More specifically, the invention relates to methods and compositions for inducing an immune response against a tumor in an animal subject. The invention provides that a lung cancer cell or other tumor cells, genetically modified to express a nucleic acid encoding CD80 (B7.1) and a nucleic acid encoding an HLA antigen, and method for stimulating an immune response to a tumor with the tumor cell so genetically modified. The invention additionally provides a method of inhibiting a tumor, including a cancer such as lung cancer, by administering an allogeneic tumor cell, for example a cancer tumor cell such as a lung cancer tumor cell, genetically modified to express a nucleic acid encoding CD80 (B7.1) and a nucleic acid encoding an HLA antigen.
FILED	Wednesday, July 29, 2015
APPL NO	14/812416
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 2039/5152 (20130101) A61K 2039/5156 (20130101)
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10279021 — Vaccine compositions and methods for restoring NKG2D pathway function against cancers

US 10279021	Dranoff et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	Dana-Faber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S)	Glenn Dranoff (Sudbury, Massachusetts); Kai W Wucherpfennig (Brookline, Massachusetts); Christopher Harvey (Boston, Massachusetts); F. Stephen Hodi (Framingham, Massachusetts)
ABSTRACT	The present invention provides compositions and methods for treating cancer in a subject by eliciting an immune response against a MIC polypeptide.
FILED	Monday, March 16, 2015
APPL NO	15/125882
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/5152 (20130101) A61K 2039/6037 (20130101) Peptides C07K 14/70539 (20130101)
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10279023 — Mucin-associated surface protein as a vaccine against chagas disease

US 10279023	Maldonado et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Rosa A. Maldonado (El Paso, Texas); Carylinda Serna (Silver Spring, Maryland); Igor C. Almeida (El Paso, Texas)
ABSTRACT	Use of synthetic peptides derived from Trypanosoma cruzi antigens and their use in vaccination against trypomastigote infection and Chagas disease. T. cruzi uses several surface proteins to invade the host. In their role of protection, the surface protients ensure the targeting and invasion of specific cells or tissues. A conserved region in the family of mucin-associated surface proteins (MASP) was used to analyze the expression of MASP at different points of invasion and proved to be important for host cell invasion, thus suggesting MASP as a candidate for vaccine development. A synthetic peptide, MASPsyn, was studied and showed efficacy in stimulating antibody and cytokine production necessary for resistance against the parasite.
FILED	Monday, February 13, 2017
APPL NO	15/430716
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/005 (20130101) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/6081 (20130101) A61K 2039/55505 (20130101) Peptides C07K 7/08 (20130101) C07K 14/44 (20130101) C07K 14/445 (20130101) Technologies for Adaptation to Climate Change Y02A 50/414 (20180101)
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10279029 — Immunogenic compositions and uses thereof

US 10279029	Croyle et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Maria A. Croyle (Austin, Texas); Stephen Clay Schafer (Austin, Texas)
ABSTRACT	Immunogenic compositions comprising viral vectors and surfactants are provided. Methods for administration and preparation of such compositions are also provided.
FILED	Tuesday, February 27, 2018
APPL NO	15/907259
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/543 (20130101) A61K 2039/55555 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/88 (20130101) C12N 2710/10343 (20130101) C12N 2710/10351 (20130101) C12N 2710/10371 (20130101) C12N 2760/14134 (20130101) C12N 2760/16134 (20130101)
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10279030 — Agents that engage antigen-presenting cells through dendritic cell asialoglycoprotein receptor (DC-ASGPR)

US 10279030	Oh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	BAYLOR RESEARCH INSTITUTE (Dallas, Texas)
ASSIGNEE(S)	Baylor Research Institute (Dallas, Texas)
INVENTOR(S)	SangKon Oh (Baltimore, Maryland); Dapeng Li (Davis, California)
ABSTRACT	The present invention includes compositions and methods for making and using anti DC-ASGPR antibodies that can, e.g., activate DCs and other cells.
FILED	Wednesday, September 14, 2016
APPL NO	15/265236
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 47/6849 (20170801) A61K 51/1027 (20130101) A61K 2039/5154 (20130101) Peptides C07K 14/005 (20130101) C07K 14/37 (20130101) C07K 14/195 (20130101) C07K 14/405 (20130101) C07K 14/435 (20130101) C07K 16/28 (20130101) C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/56 (20130101) C07K 2317/74 (20130101) C07K 2317/75 (20130101) C07K 2317/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0639 (20130101) C12N 7/00 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101)
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10279037 — Methods and materials for modulating resistance to apoptosis using KLK6 antisense and MIRNA molecules

US 10279037	Scarisbrick
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S)	Isobel A. Scarisbrick (Rochester, Minnesota)
ABSTRACT	This document provides methods and materials involved in modulating a cell's ability to be resistant to apoptosis. For example, methods and materials for exposing cells to KLK6 polypeptides, or increased KLK6 polypeptide activity, to promote resistance to apoptosis are provided. In addition, methods and materials for reducing the ability of KLK6 polypeptides to promote resistance to apoptosis are provided.
FILED	Tuesday, May 02, 2017
APPL NO	15/584822
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 38/4853 (20130101) A61K 39/39558 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6445 (20130101) Enzymes C12Y 304/21008 (20130101)
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10279044 — Bone fracture repair by targeting of agents that promote bone healing

US 10279044	Low et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Purdue Research Foundation Office of Technology Commercialization (West Lafayette, Indiana); University of Utah Research Foundation (Salt Lake City, Utah); Jindrich Kopecek (Salt Lake City, Utah); Jiyan Yang (Salt Lake City, Utah)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana); University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Stewart Andrew Low (West Lafayette, Indiana); Philip S. Low (West Lafayette, Indiana); Christopher Galliford (Silver Spring, Maryland); Jindrich Kopecek (Salt Lake City, Utah); Jiyan Yang (Salt Lake City, Utah)
ABSTRACT	Aspects of the present disclosure generally relate to compounds for targeting and healing bone fractures. Some of these compounds include a negatively charged oligopeptide comprising an acidic oligopeptide, a linker, which may be hydrolyzable or may be a substrate for the protease cathepsin K, and at least one molecule that promotes bone healing. In some compounds the molecule that promotes bone healing is an anabolic compound that inhibits GSK3β, in some compounds the molecule that promotes the healing of bone fracture is a pro-inflammatory agent such as PGE1. Other embodiments include methods of treating a bone fracture comprising administering a therapeutic amount of any one of the compounds disclosed herein.
FILED	Sunday, May 29, 2016
APPL NO	15/578226
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 31/404 (20130101) A61K 47/42 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/22 (20130101) A61L 27/54 (20130101) A61L 27/227 (20130101) A61L 2400/06 (20130101) A61L 2430/02 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/002 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/00 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101)
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10279051 — Non-human mammal model of human degenerative disorder, uses thereof, and method of treating human degenerative disorder

US 10279051	Goldman
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	University of Rochester (Rochester, New York)
ASSIGNEE(S)	University of Rochester (Rochester, New York)
INVENTOR(S)	Steven A. Goldman (Webster, New York)
ABSTRACT	The present application relates to a non-human mammal model of a human neurodegenerative disorder, methods of producing the non-human mammal model, and methods of using the non-human mammal model to identify agents suitable for treating a neurodegenerative disorder. The present application also relates to methods of treating neurodegenerative disorders and restoring normal brain interstitial potassium levels.
FILED	Friday, February 10, 2017
APPL NO	15/429585
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 2207/12 (20130101) A01K 2207/15 (20130101) A01K 2227/105 (20130101) A01K 2267/0318 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) A61K 35/545 (20130101) A61K 45/06 (20130101) A61K 49/0008 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/06 (20130101) C12N 5/0622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) G01N 33/5085 (20130101) G01N 2800/28 (20130101) G01N 2800/2814 (20130101) G01N 2800/2821 (20130101) G01N 2800/2835 (20130101)
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10279145 — Catheter placement assist device and method of use

US 10279145	Meddings et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Jennifer Meddings (Ann Arbor, Michigan); John O. Delancey (Ann Arbor, Michigan); James A. Ashton-Miller (Ann Arbor, Michigan); Dee E. Fenner (Ann Arbor, Michigan); Sanjay Saint (Ann Arbor, Michigan)
ABSTRACT	A single-use, sterile, disposable catheter placement assist device to aid in the sterile placement of transurethral urinary catheters in female patients, and a method for catheter placement using the device. The catheter placement assist device includes a labia separator with flared wings having a curved profile. The wings meet at a valley. The catheter placement assist device also includes a posterior shield that covers the perineal tissues including the anus to prevent contamination of the sterile catheter with bacteria and may further include a spout that may be shallowly inserted into the vagina to position the catheter device to optimize labial separation, retraction of the posterior vaginal wall, perineal shielding, and visualization of the urethral meatus. The additional features of a light, a handle, a catheter tip holder, a swab storage location, and a stackable configuration may further be included with the catheter placement assist device.
FILED	Monday, August 06, 2018
APPL NO	16/055390
ART UNIT	3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Diagnosis; Surgery; Identification A61B 46/30 (20160201) A61B 90/40 (20160201) A61B 2046/234 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/01 (20130101) A61M 25/0017 (20130101) A61M 25/0111 (20130101) Original (OR) Class A61M 2025/0191 (20130101) A61M 2210/1092 (20130101)
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10280183 — Therapeutic agent for treating tumors

US 10280183	Ojima et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
ASSIGNEE(S)	THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
INVENTOR(S)	Iwao Ojima (Port Jefferson, New York); Jacob Vineberg (Merrick, New York); Tao Wang (Jersey City, New Jersey)
ABSTRACT	The present disclosure relates to a therapeutic agent of the formula: Z—C(═O)—(CH₂)n-Φ-S—S—(CRR′)m-(CH₂)p-C(═O)—NH—(CH₂)q-NH—Y[NH—(CH₂)r-X-T-W][NH—(CH₂—CH—O)t(CH₂)s-NH—V] Formula I or a pharmaceutically acceptable salt thereof, useful for treating tumors, including cancers. Where the compound of Formula I also contains a radionuclide or an imaging agent or both, the compound of formula I is a theranostic agent useful for treating and diagnosing tumors, including cancers.
FILED	Wednesday, March 18, 2015
APPL NO	15/127083
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 251/18 (20130101) C07D 251/54 (20130101) C07D 519/00 (20130101) Original (OR) Class
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10280197 — Discovery of the first selective C5A receptor 2 (C5L2/C5AR2) ligands

US 10280197	Monikis et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical and Transport Systems (CTS)
APPLICANT(S)	The Regents of the University of California (Oakland, California); The Texas A and M University System (College Station, Texas); The University of Queensland (St. Lucia, Australia); University of Sheffield (Sheffield, United Kingdom)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); The Texas A and M University System (College Station, Texas); The University of Queensland (St. Lucia, Australia); The University of Sheffield (Sheffield, United Kingdom)
INVENTOR(S)	Dimitrios Monikis (Riverside, California); Christodoulos Floudas (, None); Trent Woodruff (Carindale, Australia); Matthew A. Cooper (Chapel Hill, Australia); Daniel E. Croker (Kenmore, Australia); Peter N. Monk (Sheffield, United Kingdom)
ABSTRACT	A method of selectively modulating the activity of C5a receptor 2 (C5aR2). The method includes exposing the receptor to a compound that selectively modulates C5aR2 compared to C5a receptor 1 (C5aR1). In some cases, the compound is peptide P32 or P59. Methods of recruiting β-arrestin 2 in a cell, modulating C5a-induced ERK1/2 activation in a macrophage, selectively inhibiting the release of IL-6 from a macrophage, are also provided.
FILED	Monday, October 17, 2016
APPL NO	15/295979
ART UNIT	1675 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 5/0808 (20130101) C07K 5/0812 (20130101) C07K 7/06 (20130101) Original (OR) Class
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10280204 — Electroactive biopolymer optical and electro-optical devices and method of manufacturing the same

US 10280204	Kaplan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	TUFTS UNIVERSITY (Medford, Massachusetts)
ASSIGNEE(S)	Tufts University (Medford, Massachusetts)
INVENTOR(S)	David L. Kaplan (Concord, Massachusetts); Fiorenzo Omenetto (Lexington, Massachusetts); Brian Lawrence (Minneapolis, Minnesota); Mark Cronin-Golomb (Reading, Massachusetts)
ABSTRACT	A method of manufacturing a biopolymer optical device includes providing a polymer, providing a substrate, casting the polymer on the substrate, and enzymatically polymerizing an organic compound to generate a conducting polymer between the provided polymer and the substrate. The polymer may be a biopolymer such as silk and may be modified using organic compounds such as tyrosines to provide a molecular-level interface between the provided bulk biopolymer of the biopolymer optical device and a substrate or other conducting layer via a tyrosine-enzyme polymerization. The enzymatically polymerizing may include catalyzing the organic compound with peroxidase enzyme reactions. The result is a carbon-carbon conjugated backbone that provides polymeric “wires” for use in polymer and biopolymer optical devices. An all organic biopolymer electroactive material is thereby provided that provides optical functions and features.
FILED	Thursday, February 18, 2016
APPL NO	15/046903
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/02 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0074 (20130101) B29D 11/00663 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Peptides C07K 14/43586 (20130101) Original (OR) Class Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2211/04 (20130101) D10B 2401/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/544 (20130101) G01N 33/5436 (20130101) G01N 33/54373 (20130101) G01N 33/54386 (20130101) G01N 2333/43578 (20130101) Optical Elements, Systems, or Apparatus G02B 1/04 (20130101) G02B 1/005 (20130101) G02B 1/06 (20130101) G02B 1/041 (20130101) G02B 1/045 (20130101) G02B 1/046 (20130101) G02B 5/18 (20130101) G02B 6/138 (20130101) G02B 2006/1213 (20130101) G02B 2006/12102 (20130101) G02B 2006/12104 (20130101) G02B 2006/12107 (20130101) G02B 2006/12171 (20130101)
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10280225 — Compositions and methods for non-myeloablative conditioning

US 10280225	Scadden et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S)	David T. Scadden (Weston, Massachusetts); Rahul Palchaudhuri (Cambridge, Massachusetts); Derrick J. Rossi (Roslindale, Massachusetts); Agnieszka D. Czechowicz (Boston, Massachusetts)
ABSTRACT	Disclosed herein are non-myeloablative antibody-toxin conjugates and compositions that target cell surface markers, such as the CD34, CD45 or CD117 receptors, and related methods of their use to effectively conditioning a subject's tissues (e.g., bone marrow tissue) prior to engraftment or transplant. The compositions and methods disclosed herein may be used to condition a subject's tissues in advance of, for example, hematopoietic stem cell transplant and advantageously such compositions and methods do not cause the toxicities that are commonly associated with traditional conditioning methods.
FILED	Friday, May 06, 2016
APPL NO	15/148837
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 38/164 (20130101) A61K 38/168 (20130101) A61K 47/6825 (20170801) A61K 47/6849 (20170801) A61K 47/6898 (20170801) Peptides C07K 4/04 (20130101) C07K 16/289 (20130101) C07K 16/2866 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) G01N 33/56966 (20130101) G01N 33/57407 (20130101) G01N 33/57434 (20130101)
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10280307 — Class of stable heptamethine cyanine fluorophores and biomedical applications thereof

US 10280307	Schnermann et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Martin John Schnermann (Rockville, Maryland); Roger Rauhauser Nani (Frederick, Maryland); James Blaine Shaum (Frederick, Maryland)
ABSTRACT	Embodiments of C4′-alkyl-ether heptamethine cyanine fluorophores according to general formula I, and pharmaceutically acceptable salts thereof, are disclosed. Methods of making and using the C4′-alkyl-ether heptamethine cyanine fluorophores also are disclosed.
FILED	Wednesday, November 05, 2014
APPL NO	15/524567
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) Heterocyclic Compounds C07D 209/10 (20130101) C07D 209/12 (20130101) C07D 209/14 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 23/086 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1018 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101)
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10280342 — Adhesive materials and methods of making and using the same

US 10280342	Waite et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Herbert J. Waite (Goleta, California); B. Kollbe Ahn (Goleta, California); Craig J. Hawker (Santa Barbara, California); Jinhwa Heo (Suwon, South Korea); Taegon Kang (Suwon, South Korea)
ABSTRACT	A compound of formula (I): can be used as a monomer for making an underwater adhesive polymer. The compound of formula (I) can be prepared using eugenol as a starting material.
FILED	Wednesday, July 30, 2014
APPL NO	14/908956
ART UNIT	1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 33/20 (20130101) C07C 33/025 (20130101) C07C 33/26 (20130101) C07C 33/30 (20130101) C07C 39/19 (20130101) C07C 39/20 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1804 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 12/24 (20130101) C08F 16/26 (20130101) C08F 30/08 (20130101) C08F 220/30 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 4/06 (20130101) C09J 125/18 (20130101) C09J 129/02 (20130101) C09J 143/04 (20130101) Original (OR) Class
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10280398 — Midbrain dopamine (DA) neurons for engraftment

US 10280398	Studer et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S)	MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
INVENTOR(S)	Lorenz Studer (New York, New York); Jae-Won Shim (New York, New York); Sonja Kriks (New York, New York)
ABSTRACT	The present invention relates to the field of stem cell biology, in particular the lineage specific differentiation of pluripotent or multipotent stem cells, which can include, but is not limited to, human embryonic stem cells (hESC) in addition to nonembryonic human induced pluripotent stem cells (hiPSC), somatic stem cells, stem cells from patients with a disease, or any other cell capable of lineage specific differentiation. Specifically described are methods to direct the lineage specific differentiation of hESC and/or hiPSC into floor plate midbrain progenitor cells and then further into large populations of midbrain fate FOXA2+LMX1A+TH+ dopamine (DA) neurons using novel culture conditions. The midbrain fate FOXA2+LMX1A+TH+ dopamine (DA) neurons made using the methods of the present invention are further contemplated for various uses including, but not limited to, use in in vitro drug discovery assays, neurology research, and as a therapeutic to reverse disease of, or damage to, a lack of dopamine neurons in a patient. Further, compositions and methods are provided for differentiating midbrain fate FOXA2+LMX1A+TH+ dopamine (DA) neurons from human pluripotent stem cells for use in disease modeling, in particular Parkinson's disease. Additionally, authentic DA neurons are enriched for markers, such as CD142, and A9 type neuronal cells.
FILED	Friday, November 02, 2012
APPL NO	14/356042
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 5/0623 (20130101) C12N 2501/01 (20130101) C12N 2501/13 (20130101) C12N 2501/15 (20130101) C12N 2501/16 (20130101) C12N 2501/41 (20130101) C12N 2501/119 (20130101) C12N 2501/415 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101)
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10280400 — Method for producing retinal ganglion cells from pluripotent cells

US 10280400	Ohlemacher et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S)	Sarah K. Ohlemacher (Indianapolis, Indiana); Jason S. Meyer (Zionsville, Indiana)
ABSTRACT	A method of making retinal ganglion cells, comprises the steps of: (a) differentiating pluripotent stem cells into retinal progenitor cells; and, (b) differentiating retinal progenitor cells into retinal ganglion cells.
FILED	Tuesday, May 05, 2015
APPL NO	15/308796
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/062 (20130101) Original (OR) Class C12N 5/0621 (20130101) C12N 2500/05 (20130101) C12N 2500/32 (20130101) C12N 2500/38 (20130101) C12N 2501/11 (20130101) C12N 2501/91 (20130101) C12N 2501/115 (20130101) C12N 2501/415 (20130101) C12N 2506/02 (20130101) C12N 2509/00 (20130101)
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10280405 — Methods of propagating rhinovirus C in previously unsusceptible cell lines

US 10280405	Gern et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	James E. Gern (Madison, Wisconsin); Yury A. Bochkov (Fitchburg, Wisconsin); Ann C. Palmenberg (Madison, Wisconsin)
ABSTRACT	The present invention provides methods of propagating rhinovirus C (RV-C) in a host cell; a host cell comprising an effective amount of a heterologous CDHR3 receptor such that the host cell can support propagation of rhinovirus C; and kits comprising at least one host cell previously unable to support rhinovirus C growth, wherein the host cell comprises a heterologous CDHR3 receptor and a sample of rhinovirus C. Methods of use are also provided.
FILED	Tuesday, March 06, 2018
APPL NO	15/913058
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2770/32751 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) G01N 2333/095 (20130101) G01N 2500/10 (20130101)
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10280408 — Method of suppressing gene transcription through histone lysine methylation

US 10280408	Zhou et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York)
ASSIGNEE(S)	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York)
INVENTOR(S)	Ming-ming Zhou (Old Greenwich, Connecticut); Shiraz Mujtaba (New York, New York)
ABSTRACT	The present invention relates to methods of suppressing the transcriptional expression of one or more genes by methylating the chromatin histone proteins of the one or more genes. Specifically, a viral SET domain histone lysine mehtyltransferase (vSET or vSET-like protein) methylates lysine 27 of a gene's histone protein 3 (H3-K27) thereby suppressing the transcription of the gene.
FILED	Thursday, January 21, 2016
APPL NO	15/003174
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/43 (20130101) A61K 48/00 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/09 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1007 (20130101) Original (OR) Class C12N 2710/00022 (20130101) C12N 2710/10343 (20130101) C12N 2740/15043 (20130101) Enzymes C12Y 201/01043 (20130101)
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10280415 — Human cystathionine β-synthase variants and methods of production thereof

US 10280415	Kraus
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	The Regents of the University of Colorado, a Body Corporate (Denver, Colorado)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado)
INVENTOR(S)	Jan P. Kraus (Littleton, Colorado)
ABSTRACT	Human cystathionine β-synthase variants are disclosed, as well as a method to produce recombinant human cystathionine β-synthase and variants thereof. More particularly, the role of both the N-terminal and C-terminal regions of human CBS has been studied, and a variety of truncation mutants and modified CBS homologs are described. In addition, a method to express and purify recombinant human cystathionine β-synthase (CBS) and variants thereof which have only one or two additional amino acid residues at the N-terminus are described.
FILED	Tuesday, March 14, 2017
APPL NO	15/458081
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Original (OR) Class Enzymes C12Y 402/01022 (20130101)
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10280450 — Detection of unlabeled nucleic acids by changing solubility of surface-associating probes

US 10280450	Levicky et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	New York University (New York, New York)
ASSIGNEE(S)	New York University (New York, New York)
INVENTOR(S)	Rastislav Levicky (Fairfield, Connecticut); Wanqiong Qiao (Brooklyn, New York); Yatao Liu (Tustin, California)
ABSTRACT	Provided are methods and devices for detection of unlabeled nucleic acids. The detection methods are based on change of solubility of hydrophobic probes upon hybridization with a polynucleotide. In one embodiment, the probes are morpholino probes, having a fluorophore attached thereto. The morpholino probes are immobilized on a substrate that has fluorescence quenching functionality.
FILED	Thursday, November 13, 2014
APPL NO	14/540668
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) Original (OR) Class C12Q 1/6816 (20130101) C12Q 2525/113 (20130101) C12Q 2565/101 (20130101) C12Q 2565/519 (20130101)
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10280451 — Detection of genome editing

US 10280451	Berman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Bio-Rad Laboratories, Inc. (Hercules, California); J. David Gladstone Institutes (San Francisco, California)
ASSIGNEE(S)	Bio-Rad Laboratories, Inc. (Hercules, California); J. David Gladstone Institutes (San Francisco, California)
INVENTOR(S)	Jennifer Berman (San Carlos, California); Samantha Cooper (Berkeley, California); George Karlin-Neumann (Palo Alto, California); Yuichiro Miyaoka (San Francisco, California); Bruce Conklin (San Francisco, California); Josh Shinoff (Emeryville, California)
ABSTRACT	Methods, compositions, and kits are provided for quantification of genome editing.
FILED	Friday, January 08, 2016
APPL NO	14/991818
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/102 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 2537/143 (20130101) C12Q 2563/159 (20130101) C12Q 2565/101 (20130101)
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10280464 — DNA methylation and genotype specific biomarker of suicide attempt and/or suicide ideation

US 10280464	Kaminsky et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Zachary Kaminsky (Baltimore, Maryland); Holly Wilcox (Baltimore, Maryland)
ABSTRACT	The present invention relates to the field of biomarkers. More specifically, the present invention relates to the use of biomarkers to predict suicide ideation and/or suicide attempt. In one embodiment, a method for predicting suicide ideation and/or attempt by a subject comprises the steps of (a) measuring the DNA methylation level of a CpG dinucleotide in the 3′ untranslated region of SKA2; (b) identifying the genotype at a SNP within the 3′ UTR of SKA2, and (c) predicting suicide ideation and/or attempt by the subject using a prediction algorithm.
FILED	Friday, July 11, 2014
APPL NO	14/904233
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/154 (20130101)
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10281399 — Systems and methods for particle tracking using spatiotemporal offset light beams

US 10281399	Dunn et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Andrew Dunn (Austin, Texas); Hsin-Chih Yeh (Austin, Texas); Evan Perillo (Austin, Texas)
ABSTRACT	Systems and methods for particle tracking using spatiotemporal offset light beams. In exemplary embodiments, the optical systems and methods can be used with conventional two-photon microscopy equipment to perform high speed, high precision, and deep tissue three-dimensional single-particle tracking. Exemplary embodiments can be configured for single-molecule studies of biological diffusion and transport processes.
FILED	Thursday, February 05, 2015
APPL NO	15/548861
ART UNIT	2884 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) G01N 21/6408 (20130101) G01N 21/6428 (20130101) Original (OR) Class G01N 21/6456 (20130101) G01N 2021/6439 (20130101)
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10281451 — Method of determining the viability of at least one cell

US 10281451	Mycek et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Mary-Ann Mycek (Ann Arbor, Michigan); Stephen Feinberg (Ann Arbor, Michigan); Cynthia Marcelo (Ann Arbor, Michigan); William Lloyd (Wixom, Michigan); Leng-Chun Chen (Ann Arbor, Michigan); Shiuhyang Kuo (Dexter, Michigan); Hyungjin Myra Kim (Ann Arbor, Michigan)
ABSTRACT	This disclosure provides a method of determining the viability of at least one cell via quantification of nicotinamide adenine dinucleotide (phosphate) (NAD(P)H), flavin adenine dinucleotide (FAD), and/or collagen. The method includes the steps of contacting the at least one cell with light having a wavelength of from 700 to 900 nm, using two photon excitation, or from 335 to 400 nm, using one photon excitation, to induce an optical response from the NAD(P)H, FAD, and/or collagen and measuring the optical response. The method also includes the step of quantifying one or more of an amount, spatial localization, and/or time-dependent response of the NAD(P)H, FAD, and/or collagen utilizing the optical response.
FILED	Thursday, July 03, 2014
APPL NO	14/323790
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6408 (20130101) G01N 21/6456 (20130101) G01N 33/582 (20130101) G01N 33/4833 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 33/5735 (20130101) G01N 33/6887 (20130101) G01N 2333/46 (20130101) G01N 2333/78 (20130101)
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10281473 — Compositions and methods for analysis of protein sequences and post-translational modifications

US 10281473	Hunt et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	University of Virginia Patent Foundation (Charlottesville, Virginia); Donald F. Hunt (Charlottesville, Virginia); Weihan Wang (Charlottesville, Virginia); Lichao Zhang (Mountain View, California)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	Donald F. Hunt (Charlottesville, Virginia); Weihan Wang (Charlottesville, Virginia); Lichao Zhang (Mountain View, California)
ABSTRACT	The application discloses compositions, methods, systems, and apparatuses for rapid sequence analysis of proteins, including location of post-translational modifications and disulfide bonds. Limited digestion of fully denatured antibody occurs in seconds by flowing sample in 8M urea at constant pressure through a micro column reactor containing immobilized aspergillopepsin I, resulting in a product mixture containing 3-10 kDa peptides, which is then fractionated by capillary column chromatography and analyzed by both electron transfer dissociation (ETD) and collision activated dissociation mass spectrometry. This method provides 95% sequence coverage of a mAb and detects numerous post-translational modifications. For disulfide bond location, native mAb is subjected to longer digestion times. Release of disulfide containing peptides from accessible regions of the folded protein occurs with short digestion times. The identity of peptides connected by a disulfide bond is determined using ETD and ion-ion proton transfer chemistry.
FILED	Wednesday, February 04, 2015
APPL NO	15/116609
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) Original (OR) Class G01N 33/6854 (20130101) G01N 2440/00 (20130101) G01N 2440/16 (20130101) G01N 2440/20 (20130101) G01N 2440/38 (20130101) G01N 2560/00 (20130101)
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10281474 — Method for analyzing samples of biological fluid and apparatus for performing the same

US 10281474	Regnier et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Novilytic, LLC (West Lafayette, Indiana)
ASSIGNEE(S)
INVENTOR(S)	Fred Regnier (Carmel, Indiana); JinHee Kim (West Lafayette, Indiana)
ABSTRACT	The present invention relates to methods for continuous or near-continuous separation and purification of samples, particularly biological samples, to reduce the number or volume of non-targeted analytes in those samples to enable improved mass spectrometric analysis of analytes of interest, and apparatuses for conducting those methods, utilizing a transport agent with a core domain and a binding domain, the transport agent exceeding 200 kiloDaltons or 10 nm, and the binding domain targeted to the analytes of interest, in conjunction with size-exclusion based chromatography to separate the transport agent-analyte of interest complex from non-targeted analytes that are not bound, or are only non-specifically bound, to the transport agent.
FILED	Thursday, June 07, 2018
APPL NO	16/002798
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) Original (OR) Class G01N 33/54313 (20130101)
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10281475 — Systems and methods to identify and treat subjects at risk for obstetrical complications

US 10281475	Chaiworapongsa et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	Wayne State University (Detroit, Michigan); The United States of America as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	Wayne State University (Detroit, Michigan); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia)
INVENTOR(S)	Tinnakorn Chaiworapongsa (Grosse Pointe Park, Michigan); Sonia S. Hassan (Novi, Michigan); Roberto Romero (Grosse Pointe, Michigan)
ABSTRACT	Provided are systems and methods for assessing the presence or risk of obstetrical complications, particularly those related to an angiogenic and anti-angiogenic imbalance. Also provided are methods of treating an angiogenic and anti-angiogenic imbalance with water-soluble statins, such as pravastatin.
FILED	Friday, March 27, 2015
APPL NO	15/129771
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/22 (20130101) A61K 31/616 (20130101) A61K 31/727 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/689 (20130101) Original (OR) Class G01N 2333/475 (20130101) G01N 2333/912 (20130101) G01N 2800/50 (20130101) G01N 2800/368 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) G06F 19/3456 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101)
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10281476 — Methods to identify modulators of RyR calcium channels

US 10281476	Cornea et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S)	Razvan L. Cornea (Minneapolis, Minnesota); Donald M. Bers (Davis, California); David D. Thomas (Minneapolis, Minnesota); Gregory D. Gillispie (Minneapolis, Minnesota)
ABSTRACT	Provided herein are methods for identifying a compound that modulates a Ryanodine receptor (Ryr). Fluorescence resonance energy transfer between an FKBP bound to an RyR and fluorescent derivatives of RyR binding partners (e.g., calmodulin) or domain-peptide biosensors is used to provide a readout dependent on the RyR functional state. The methods permit measurement of RyR present in a permeabilized cell or in a purified membrane.
FILED	Wednesday, December 10, 2014
APPL NO	14/565811
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/326 (20130101)
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10281538 — Warm bore cylinder assembly

US 10281538	Mathieu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Jean-Baptiste Mathieu (Clifton Park, New York); Evangelos Trifon Laskaris (Schenectady, New York); Kenneth William Rohling (Troy, New York); Minfeng Xu (Ballston Lake, New York); Seung-Kyun Lee (Cohoes, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Jean-Baptiste Mathieu (Clifton Park, New York); Evangelos Trifon Laskaris (Schenectady, New York); Kenneth William Rohling (Troy, New York); Minfeng Xu (Ballston Lake, New York); Seung-Kyun Lee (Cohoes, New York)
ABSTRACT	A warm bore cylinder assembly having an outer wall, an inner wall, and a plurality of braces is provided. The outer wall is configured to define an inner exterior portion of a cryostat assembly. The outer wall is generally cylindrical, is made of a conductive material, and has an outer wall thickness. The inner wall is disposed radially inwardly of the outer wall. The inner wall is generally cylindrical, is made of a conductive material, and has an inner wall thickness. The braces extend along an axial direction defined by the outer wall and the inner wall. The plurality of braces are interposed between and join the outer wall and inner wall. The plurality of braces define openings disposed between adjacent braces.
FILED	Wednesday, September 05, 2012
APPL NO	13/603903
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/38 (20130101) G01R 33/421 (20130101) G01R 33/3804 (20130101) Original (OR) Class G01R 33/3815 (20130101) G01R 33/3873 (20130101) G01R 33/4215 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49359 (20150115)
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10281547 — Diffusion-weighted double-echo magnetic resonance fingerprinting (MRF)

US 10281547	Griswold et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Mark Griswold (Shaker Heights, Ohio); Vikas Gulani (Shaker Heights, Ohio); Dan Ma (Cleveland, Ohio); Yun Jiang (Cleveland Heights, Ohio); Katherine Wright (Macedonia, Ohio)
ABSTRACT	Apparatus, methods, and other embodiments associated with NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. Sampling is performed in response to a diffusion-weighted double-echo pulse sequence. Sampling acquires transient-state signals of the double-echo sequence. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals, and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals.
FILED	Monday, April 21, 2014
APPL NO	14/257207
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4828 (20130101) G01R 33/5608 (20130101) Original (OR) Class G01R 33/56341 (20130101)
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10281702 — Multi-focal structured illumination microscopy systems and methods

US 10281702	Shroff et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by Secretary, Depart. of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Hari Shroff (Washington, District of Columbia); Andrew York (Bethesda, Maryland)
ABSTRACT	A multi-focal structured illumination microscopy (SIM) system for generating multi-focal patterns of a sample is disclosed. The multi-focal SIM system performs a focusing, scaling and summing operation on each multi-focal pattern in a sequence of multi-focal patterns that completely scan the sample to produce a high resolution composite image.
FILED	Thursday, August 02, 2018
APPL NO	16/053533
ART UNIT	2884 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) G01N 2021/6478 (20130101) G01N 2201/0633 (20130101) Optical Elements, Systems, or Apparatus G02B 21/004 (20130101) G02B 21/0032 (20130101) G02B 21/0036 (20130101) G02B 21/0072 (20130101) Original (OR) Class G02B 21/0076 (20130101)
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10283327 — Apparatus and methods for generating reactive gas with glow discharges

US 10283327	Laux et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California); CentraleSupélec (Gif sur Yvette, France)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California); CentraleSupélec (Gif sur Yvette, France)
INVENTOR(S)	Christophe O. Laux (Antony, France); Johan O. Andreasson (Palo Alto, California); Luke C. Raymond (Stanford, California); Diane Rusterholtz-Duval (Rouen, France); David Pai (Poitier, France); Deanna Lacoste (Thuwal, Saudi Arabia); Florent Sainct (Le Cannet, France); Sebastien Mannai (Anglet, France); Florian Girschig (Aalborg, Denmark); Pierpaolo Toniato (Tombolo, Italy); Erwan Pannier (Les Martres de Veyre, France); Augustin Tibère-Inglesse (Le Crés, France)
ABSTRACT	An apparatus for generating a flow of reactive gas for decontaminating a material, surface or area, comprises a first electrode member comprising a first plurality of conductive surfaces and a second electrode member comprising a second plurality of conductive surfaces. The second electrode member is arranged in spaced relationship with the first electrode member to define a reactor channel. The conductive surfaces are exposed to the reactor channel so as to form air gaps between the first plurality of conductive surfaces and the second plurality of conductive surfaces. An air blower generates a flow of air through the reactor channel. An electric pulse generator repetitively generates voltage pulses between the first and second electrode members so as to produce glow discharges in the air gaps between the conductive surfaces of the first plurality and the conductive surfaces of the second plurality, the voltage pulses being generated at time intervals less than 1 millisecond and voltage pulse duration less than about 500 ns, the glow discharges being adapted to transform part of the flow of air into reactive gas. An output section delivers the reactive gas from the reactor channel to a sample or region to be decontaminated or treated.
FILED	Friday, June 24, 2016
APPL NO	15/192582
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/14 (20130101) A61L 2/0094 (20130101) A61L 2/202 (20130101) A61L 2202/11 (20130101) A61L 2202/21 (20130101) Separation B01D 2258/06 (20130101) B01D 2259/818 (20130101) B01D 2259/4508 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 2219/0875 (20130101) B01J 2219/0898 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/32018 (20130101) H01J 37/32027 (20130101) H01J 37/32541 (20130101) H01J 37/32568 (20130101) Original (OR) Class H01J 37/32844 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/48 (20130101) H05H 2001/483 (20130101) H05H 2001/4697 (20130101) H05H 2245/1225 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 20/30 (20130101)
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Department of Energy (DOE)

10278649 — Methods and systems for detecting cancer

US 10278649	Hayat et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA)
APPLICANT(S)	STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Majeed M. Hayat (Albuquerque, New Mexico); Sanjay Krishna (Albuquerque, New Mexico); Sebastian Eugenio Godoy (Albuquerque, New Mexico); David A. Ramirez (Albuquerque, New Mexico)
ABSTRACT	A technique for classifying lesions as malignant or benign is disclosed. The technique can include: cooling an area of skin including a lesion of a patient to initiate a warm-up process; receiving a temporal sequence of thermal images of the area of skin representing a thermal recovery of the area of skin, the temporal sequence of thermal images generated by an infrared camera; generating a temporal profile of the thermal recovery based on the temporal sequence of thermal images; analyzing temporal statistical properties of the temporal profile; determining a malignancy probability that the lesion is malignant based on an analysis of the temporal profile, wherein the determining includes extracting one or more statistical features based on continuous-time stochastic signals in the sequence of thermal images; and classifying the lesion based on the malignancy probability.
FILED	Tuesday, November 24, 2015
APPL NO	15/531135
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/015 (20130101) A61B 5/444 (20130101) A61B 5/489 (20130101) A61B 5/7264 (20130101) A61B 5/7275 (20130101) Original (OR) Class Electric Digital Data Processing G06F 19/00 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6214 (20130101) G06K 9/6277 (20130101) Image Data Processing or Generation, in General G06T 7/13 (20170101) G06T 7/0016 (20130101) G06T 7/40 (20130101) G06T 7/62 (20170101) G06T 7/68 (20170101) G06T 7/90 (20170101) G06T 7/174 (20170101) G06T 7/277 (20170101) G06T 2207/10016 (20130101) G06T 2207/10048 (20130101) G06T 2207/30088 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101)
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10279054 — Pet imaging of zinc transport

US 10279054	Degrado et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Timothy R. Degrado (Rochester, Massachusetts); Mukesh K. Pandey (Rochester, Minnesota); Hendrik Petrus Engelbrecht (Rochester, Minnesota); Val J. Lowe (Rochester, Minnesota)
ASSIGNEE(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S)	Timothy R. Degrado (Rochester, Massachusetts); Mukesh K. Pandey (Rochester, Minnesota); Hendrik Petrus Engelbrecht (Rochester, Minnesota); Val J. Lowe (Rochester, Minnesota)
ABSTRACT	A method for producing a solution including a positron emitting zinc cation of ⁶³Zn, and the method comprises bombarding a solution target including ⁶³Cu with high energy protons to produce a solution including a positron emitting zinc cation. A method for detecting or ruling out Alzheimer's disease in a patient comprises administering to a patient a detectable amount of a compound including a positron emitting zinc cation, wherein the zinc cation is targeted to beta-amyloid in the patient, and acquiring an image to detect the presence or absence of beta-amyloid in the patient.
FILED	Wednesday, July 09, 2014
APPL NO	14/902744
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 51/0402 (20130101) Original (OR) Class A61K 51/0478 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101)
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10279318 — Robust carbon nanotube membranes and methods of making the same

US 10279318	Dastgheib et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Seyed A. Dastgheib (Savoy, Illinois); Ali Ashraf (Beaverton, Oregon); SungWoo Nam (Savoy, Illinois)
ABSTRACT	Carbon nanotube membranes that are flexible, non-fragile, stable at high temperatures, superhydrophobic, have submicrometer openings, and are resistant to delamination and corrosive conditions are provided. The carbon nanotube membranes comprise carbon nanotubes grown on a microporous, metal substrate, e.g. silver, quartz fiber filter, and HAST. Methods of fabricating the carbon nanotubes are also provided.
FILED	Monday, November 07, 2016
APPL NO	15/344697
ART UNIT	1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 61/025 (20130101) B01D 61/027 (20130101) B01D 61/147 (20130101) B01D 61/364 (20130101) B01D 67/0039 (20130101) B01D 71/021 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/441 (20130101) C02F 1/442 (20130101) C02F 1/444 (20130101) C02F 2103/08 (20130101)
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10280201 — Polypeptides having cellulolytic enhancing activity and nucleic acids encoding same

US 10280201	Brown et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Novozymes, Inc. (Davis, California)
ASSIGNEE(S)	Novozymes, Inc. (Davis, California)
INVENTOR(S)	Kimberly Brown (Elk Grove, California); Paul Harris (Carnation, Washington); Elizabeth Zaretsky (Reno, Nevada); Edward Re (Davis, California); Elena Vlasenko (Davis, California); Keith McFarland (Davis, California); Alfredo Lopez de Leon (Davis, California)
ABSTRACT	The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
FILED	Tuesday, August 29, 2017
APPL NO	15/689443
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 14/37 (20130101) Original (OR) Class Detergent Compositions; Use of Single Substances as Detergents; Soap or Soap-making; Resin Soaps; Recovery of Glycerol C11D 3/38645 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 1/14 (20130101) C12N 1/16 (20130101) C12N 1/20 (20130101) C12N 9/2437 (20130101) C12N 9/2445 (20130101) C12N 15/52 (20130101) C12N 15/63 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/14 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2201/00 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 302/01021 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/17 (20130101)
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10280255 — Renewable resins and unsaturated polyesters and methods of making the same

US 10280255	Beckham et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado); Colorado School of Mines (Golden, Colorado)
ASSIGNEE(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S)	Gregg Tyler Beckham (Golden, Colorado); Derek R. Vardon (Golden, Colorado); Nicholas Rorrer (Golden, Colorado); John R. Dorgan (Golden, Colorado)
ABSTRACT	An aspect of the present disclosure is a bioderived polymer that includes a first repeat unit that includes where n is an integer between 1 and 1000, and R¹is a first hydrocarbon group.
FILED	Tuesday, April 25, 2017
APPL NO	15/496293
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/52 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0025 (20130101) Compositions of Macromolecular Compounds C08L 25/06 (20130101) C08L 31/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/4866 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4633 (20130101)
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10280378 — System and process for the production of renewable fuels and chemicals

US 10280378	Masel
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Dioxide Materials, Inc. (Boca Raton, Florida)
ASSIGNEE(S)	Dioxide Materials, Inc (Boca Raton, Florida)
INVENTOR(S)	Richard I. Masel (Boca Raton, Florida)
ABSTRACT	A renewable fuel production system includes a carbon dioxide capture unit for extracting carbon dioxide from atmospheric air, a carbon dioxide electrolyzer for converting carbon dioxide to carbon monoxide, a water electrolyzer for converting water to hydrogen, a synfuels generator for converting carbon monoxide produced by the carbon dioxide electrolyzer and hydrogen produced by the water electrolyzer to a fuel. The fuel produced can be synthetic gasoline and/or synthetic diesel. A renewable fuel production process includes the steps of extracting carbon dioxide from atmospheric air via a carbon dioxide capture unit, converting carbon dioxide to carbon monoxide via a carbon dioxide electrolyzer, converting water to hydrogen via a water electrolyzer, and converting carbon monoxide produced via the carbon dioxide electrolyzer and H₂produced via the water electrolyzer to a fuel. The system is also capable of simultaneously or alternatively producing a separate industrial chemical.
FILED	Wednesday, August 23, 2017
APPL NO	15/684548
ART UNIT	1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/245 (20130101) B01J 21/04 (20130101) B01J 23/80 (20130101) B01J 23/755 (20130101) B01J 23/882 (20130101) B01J 29/06 (20130101) B01J 29/40 (20130101) B01J 29/85 (20130101) B01J 35/0006 (20130101) B01J 35/1019 (20130101) Acyclic or Carbocyclic Compounds C07C 1/22 (20130101) C07C 1/22 (20130101) C07C 11/06 (20130101) C07C 29/154 (20130101) C07C 29/1518 (20130101) C07C 29/1518 (20130101) C07C 31/04 (20130101) C07C 41/09 (20130101) C07C 41/09 (20130101) C07C 43/043 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/06 (20130101) Original (OR) Class C10L 1/08 (20130101) C10L 2200/0423 (20130101) C10L 2200/0446 (20130101) C10L 2270/023 (20130101) C10L 2270/026 (20130101) C10L 2290/38 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 1/04 (20130101) C25B 9/18 (20130101) C25B 11/0478 (20130101) C25B 13/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/366 (20130101) Y02E 70/10 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101)
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10280413 — Polypeptides having cellobiohydrolase activity and polynucleotides encoding same

US 10280413	Spodsberg
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Novozymes, Inc. (Davis, California)
ASSIGNEE(S)	Novozymes, Inc. (Davis, California)
INVENTOR(S)	Nikolaj Spodsberg (Bagsvaerd, Denmark)
ABSTRACT	The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
FILED	Wednesday, September 27, 2017
APPL NO	15/717001
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/14 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 302/01091 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101)
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10280431 — Acyltransferases and methods of using

US 10280431	Cahoon et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Basic Energy Sciences (BES) Energy Frontier Research Centers (EFRC) Center for Advanced Biofuel Systems (CABS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Organismal Systems (IOS) Department of Agriculture (USDA)
APPLICANT(S)	NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S)	NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S)	Edgar Cahoon (Lincoln, Nebraska); Umidjon Iskandarov (Lincoln, Nebraska); Hae Jin Kim (Lincoln, Nebraska); Jillian Collins-Silva (Lincoln, Nebraska)
ABSTRACT	Provided herein are novel acyltransferases and methods of using such novel acyltransferases in making medium-chain fatty acids.
FILED	Thursday, December 18, 2014
APPL NO	14/576135
ART UNIT	1662 — Plants
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6463 (20130101)
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10280432 — Genetically engineered plants with increased vegetative oil content

US 10280432	Benning et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S)	Christoph Benning (East Lansing, Michigan); Sanjaya (South Charleston, West Virginia)
ABSTRACT	The invention relates to genetically modified agricultural plants with increased oil content in vegetative tissues, as well as to expression systems, plant cells, seeds and vegetative tissues related thereto.
FILED	Thursday, April 13, 2017
APPL NO	15/487063
ART UNIT	1662 — Plants
CURRENT CPC	Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1241 (20130101) C12N 15/8218 (20130101) C12N 15/8245 (20130101) C12N 15/8247 (20130101) Original (OR) Class Enzymes C12Y 207/07027 (20130101)
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10280441 — Host cells and methods for producing cinnamoyl anthranilate and analogs thereof

US 10280441	Loque et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	Dominique Loque (Albany, California); Aymerick Guillaume Eudes (Emeryville, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Dominique Loque (Albany, California); Aymerick Guillaume Eudes (Emeryville, California)
ABSTRACT	The present invention provides for a method of producing a cinnamoyl anthranilate, or analog thereof, in a genetically modified host cell.
FILED	Friday, October 14, 2011
APPL NO	13/274244
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1029 (20130101) C12N 15/81 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 13/02 (20130101) Original (OR) Class Enzymes C12Y 203/01144 (20130101) C12Y 602/01012 (20130101)
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10280483 — Solvent extraction of transition metals

US 10280483	Tkac et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	Peter Tkac (Naperville, Illinois); George F. Vandegrift, III (Crest Hill, Illinois); David A. Rotsch (Montgomery, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Peter Tkac (Naperville, Illinois); George F. Vandegrift, III (Crest Hill, Illinois); David A. Rotsch (Montgomery, Illinois)
ABSTRACT	The invention provides a continuous method for extracting transition metal, the method comprising: supplying a spent generator liquor comprising transition metal in highly alkaline solution; mixing the liquor with acid thereby generating a solution, wherein the transition metal resides within the solution; combining the solution with an organic liquid comprising tributyl phosphate or other neutral extractant to extract the transition metal within the organic liquid; washing the extracted transition metal in the organic liquid with acid so as to remove non-transition-metal salts from the organic liquid phase; and stripping the washed transition metal loadedorganic liquid phase with hydroxide, water or complexing agent to remove the transition metal from the organic phase.
FILED	Friday, August 14, 2015
APPL NO	14/826334
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/0005 (20130101) C22B 7/007 (20130101) C22B 34/34 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/234 (20151101)
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10280903 — Concentrated solar power generation using solar receivers

US 10280903	Anderson et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Wilson 247Solar, Inc. (Tortola, Virgin Islands)
ASSIGNEE(S)	Wilson 247Solar, Inc. (Tortola, Virgin Islands)
INVENTOR(S)	Bruce N. Anderson (Great Falls, Virginia); William Dean Treece (La Mesa, California); Dan Brown (Lebanon, New Hampshire); Florian Bennhold (Osnabruk, Germany); Christoph Hilgert (Odenthal, Germany)
ABSTRACT	Inventive concentrated solar power systems using solar receivers, and related devices and methods, are generally described. Low pressure solar receivers are provided that function to convert solar radiation energy to thermal energy of a working fluid, e.g., a working fluid of a power generation or thermal storage system. In some embodiments, low pressure solar receivers are provided herein that are useful in conjunction with gas turbine based power generation systems.
FILED	Wednesday, August 02, 2017
APPL NO	15/667222
ART UNIT	3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 1/04 (20130101) F02C 1/08 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 6/06 (20130101) Original (OR) Class F03G 6/064 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 10/40 (20180501) F24S 10/80 (20180501) F24S 20/20 (20180501) F24S 23/79 (20180501) F24S 70/12 (20180501) F24S 80/20 (20180501) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 19/04 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/41 (20130101) Y02E 10/44 (20130101) Y02E 10/46 (20130101)
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10281069 — Vacuum sealing flange

US 10281069	Sharma et al.
FUNDED BY	Department of Energy (DOE) Brookhaven Science Associates, LLC (BSA) Office of Science (DOE-SC) Brookhaven National Laboratory (BNL) Federally Funded Research and Development Center (FFRDC) Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S)	Brookhaven Science Associates, LLC (Upton, New York)
ASSIGNEE(S)	Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S)	Sushil Kumar Sharma (Medford, New York); Lewis Garth Doom, Jr. (Stony Brook, New York); Christopher Amundsen (Commack, New York); Muhammad Aftab Hussain (Mount Sinai, New York); Frank A. DePaola (Moriches, New York); Frank Charles Lincoln (Patchogue, New York); Charles Hetzel (Wading River, New York); Charles S. De La Parra (Manorville, New York); Paul Edward Palecek, Jr. (Ridge, New York)
ABSTRACT	Flange technologies are described for a flange comprising a first and second side. Each side may include a knife edge surface disposed circumferentially around a base surface and a periphery section disposed around the knife edge surface. The knife edge surface and the periphery section are effective to define grooves therebetween. The flange may include an alloy with a relatively high thermal conductivity and yield strength. The flange may include water channels to remove heat.
FILED	Tuesday, October 21, 2014
APPL NO	15/036186
ART UNIT	3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 23/16 (20130101) F16L 23/20 (20130101) F16L 23/032 (20130101) Original (OR) Class F16L 2201/40 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/32513 (20130101)
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10281338 — Oil-immersed transformer thermal monitoring and prediction system

US 10281338	Feng et al.
FUNDED BY	Department of Energy (DOE) Office of Electricity (DOE-OE)
APPLICANT(S)	ABB Inc. (Cary, North Carolina)
ASSIGNEE(S)	ABB Inc. (, Delaware)
INVENTOR(S)	Xianyong Feng (Cary, North Carolina); Mirrasoul J. Mousavi (Cary, North Carolina)
ABSTRACT	A real time thermal monitoring and prediction system (TMPS) is provided for use in monitoring and operating a transformer. The TMPS may be used to estimate a maximum loading level for the transformer over a future time period using a dynamic thermal model for the transformer and ambient temperature forecasts. The transformer may be loaded to its maximum loading level during power congestion or a service restoration process.
FILED	Tuesday, February 23, 2016
APPL NO	15/050538
ART UNIT	2865 — Printing/Measuring and Testing
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 1/20 (20130101) Original (OR) Class G01K 7/427 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 2027/406 (20130101) Emergency Protective Circuit Arrangements H02H 6/00 (20130101) H02H 7/04 (20130101)
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10281343 — Method and apparatus for measuring a peak load

US 10281343	Bullen et al.
FUNDED BY	Department of Energy (DOE) Knolls Atomic Power Laboratory (KAPL) National Nuclear Security Administration (NNSA) Naval Nuclear Laboratory (NNL)
APPLICANT(S)	United States Department of Energy (Washington, District of Columbia)
ASSIGNEE(S)	U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S)	David A. Bullen (North Huntingdon, Pennsylvania); Brian A. McGraw (Pittsburgh, Pennsylvania)
ABSTRACT	The present subject matter discloses a method of measuring a peak load, including the steps of placing an indenter between a first surface and a second surface, exerting a load on at least one of the first and second surfaces, measuring at least one of a width, depth, radial chord length, and cross-sectional area of an indentation formed by the indenter in at least one of the first and second surfaces; and converting the measured parameter into a load value. Certain methods further include the steps of converting the measured parameter into a load per length value and obtaining a load value by integrating along a circumferential length of the indentation. In still other methods, the exerted load is a compressive load.
FILED	Tuesday, June 07, 2016
APPL NO	15/175110
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 21/32 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/06 (20130101) Original (OR) Class G01L 5/243 (20130101)
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10281364 — System and method for using engine efficiency in predictive maintenance of a power generator

US 10281364	Kallhoff et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Cummins Power Generation IP, Inc. (Minneapolis, Minnesota)
ASSIGNEE(S)	Cummins Power Generation IP, Inc. (Minneapolis, Minnesota)
INVENTOR(S)	Dustin Wayne Kallhoff (Maple Grove, Minnesota); Benjamin S. Fuchs (Andover, Minnesota)
ABSTRACT	Methods, systems and apparatuses for early fault detection of a power generator are provided. An alternator output power parameter is received and a fuel flow input measurement is received. An estimated engine efficiency value is determined in response to the alternator output power parameter and the fuel flow input measurement. The estimated engine efficiency value may be transmitted to a monitoring device.
FILED	Thursday, March 10, 2016
APPL NO	15/066648
ART UNIT	2895 — Semiconductors/Memory
CURRENT CPC	Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 99/008 (20130101) Original (OR) Class
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10281378 — System and method for testing true stress and true strain

US 10281378	Wenski
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Kansas City National Security Campus (KCNSC) NNSA Critical Mission Site Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S)	HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES LLC (Kansas City, Missouri)
ASSIGNEE(S)	Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S)	Edward Wenski (Lenexa, Kansas)
ABSTRACT	A true stress testing system broadly comprising a force input machine, an imaging system, and a computer. The imaging system includes a light source for projecting a light beam at the specimen in a first direction and a camera positioned on an opposite side of the specimen for receiving portions of the light beam not blocked by the specimen such that a shadow image of the specimen is created via the camera. The computer may determine a minimum dimension of the specimen perpendicular to the first direction at a point in time over a plurality of points along the force axis via the shadow image of the specimen such that the processor accounts for changes in position of the minimum dimension along the specimen. A true stress of the specimen may then be determined according to the minimum dimension of the specimen perpendicular to the first direction at the point in time.
FILED	Thursday, May 05, 2016
APPL NO	15/147055
ART UNIT	2487 — Recording and Compression
CURRENT CPC	Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/24 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 11/081 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/08 (20130101) G01N 3/068 (20130101) Original (OR) Class G01N 2203/0264 (20130101) G01N 2203/0647 (20130101) Image Data Processing or Generation, in General G06T 7/62 (20170101) Pictorial Communication, e.g Television H04N 5/247 (20130101) H04N 5/2256 (20130101)
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10281598 — Compositions and methods for monitoring actinides

US 10281598	Taleyarkhan
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Rusi Taleyarkhan (Lafayette, Indiana)
ABSTRACT	Compositions and methods for monitoring the quantity of actinides present in a test sample are disclosed. Compositions and methods for monitoring the motion of special nuclear materials through space are also described. Compositions and methods for monitoring the quantity of a fissile special nuclear material present in a test sample are disclosed. Compositions and methods for monitoring actinides during reprocessing of spent nuclear fuel after 30-year cool down are disclosed. Compositions and methods for monitoring actinides during reprocessing of spent nuclear fuel after 180 day cool down are also disclosed.
FILED	Friday, March 14, 2014
APPL NO	14/777307
ART UNIT	2884 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/00 (20130101) G01N 23/00 (20130101) Measurement of Nuclear or X-radiation G01T 3/00 (20130101) G01T 3/008 (20130101) G01T 5/06 (20130101) Original (OR) Class
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10281600 — Neutron detector and dose rate meter using beryllium-loaded materials

US 10281600	Degtiarenko
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Thomas Jefferson National Accelerator Facility (TJNAF) Federally Funded Research and Development Center (FFRDC) Operated by Jefferson Science Associates, LLC (JSA) at Newport News, VA
APPLICANT(S)	JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia)
ASSIGNEE(S)	JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia)
INVENTOR(S)	Pavel V. Degtiarenko (Williamsburg, Virginia)
ABSTRACT	An apparatus and method for improving the sensitivity and energy response of neutron detectors and neutron dose rate meters. A beryllium layer is added to neutron detector moderators to improve the sensitivity of the detector. Energy dependence of the sensitivity is optimized by controlling the amount of beryllium in the moderator and by specifying the geometrical design parameters. The beryllium layer, in combination with additional material layers in the moderator, makes the detector response function correspond to the theoretical one in a wide range of energies. Response parameters of the neutron dose rate meter are within 20% of the theoretical response function in the neutron energy range from 500 keV to 10 GeV, and also in the energy range corresponding to thermal neutrons (about 1-100 meV).
FILED	Wednesday, April 11, 2018
APPL NO	15/950298
ART UNIT	2884 — Optics
CURRENT CPC	Measurement of Nuclear or X-radiation G01T 3/00 (20130101) G01T 3/06 (20130101) G01T 3/008 (20130101) G01T 7/00 (20130101) Original (OR) Class
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10282309 — Per-page control of physical address space distribution among memory modules

US 10282309	Jayasena et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Advanced Micro Devices, Inc. (Sunnyvale, California)
ASSIGNEE(S)	Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S)	Nuwan S. Jayasena (Sunnyvale, California); Hyojong Kim (Atlanta, Georgia); Hyesoon Kim (Atlanta, Georgia)
ABSTRACT	Systems, apparatuses, and methods for implementing per-page control of physical address space distribution among memory modules are disclosed. A computing system includes a plurality of processing units coupled to a plurality of memory modules. A determination is made as to which physical address space distribution granularity to implement for physical memory pages allocated for a first data structure. The determination can be made on a per-data-structure basis (e.g., file, page, block, etc.) or on a per-application-basis. A physical address space distribution granularity is encoded as a property of each physical memory page allocated for the first data structure, and physical memory pages of the first data structure distributed across the plurality of memory modules based on a selected physical address space distribution granularity. Page table entries (PTEs) may be annotated with the selected physical address space distribution granularity, using an addressing mapping granularity (AMG) field of a page table entry, where the granularity may be, for example, a fine-grain distribution granularity or a coarse-grain distribution granularity.
FILED	Friday, February 24, 2017
APPL NO	15/441532
ART UNIT	2135 — Memory Access and Control
CURRENT CPC	Electric Digital Data Processing G06F 12/0623 (20130101) G06F 12/1009 (20130101) G06F 12/1027 (20130101) Original (OR) Class G06F 2212/68 (20130101) G06F 2212/656 (20130101)
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10282795 — Real-time forecasting of electricity demand in a streams-based architecture with applications

US 10282795	Ghosh et al.
FUNDED BY	Department of Energy (DOE) Office of Electricity (DOE-OE)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Soumyadip Ghosh (Peekskill, New York); Jonathan R. Hosking (Scarsdale, New York); Ramesh Natarajan (Pleasantville, New York); Shivaram Subramanian (New Fairfield, Connecticut); Xiaoxuan Zhang (Jersey City, New Jersey)
ABSTRACT	A streams platform is used. Multiple streams of electricity usage data are received, each from an electrical meter providing periodic updates to electrical usage for devices connected to the electrical meter. Weather information is received corresponding to locations where the electrical meters are. Real-time predictive modeling of electricity demand is performed based on the received multiple streams of electricity usage data and the received weather information, at least by performing: updating a state space model for electrical load curves using the usage data from the streams and the weather, wherein the updating uses current load observations for the multiple streams for a current time period; and creating forecast(s) for the electricity demand. The forecast(s) of the electricity demand are output. Appliance-level predictions may be made and used, and substitution effects and load management functions may be performed.
FILED	Wednesday, June 22, 2016
APPL NO	15/189173
ART UNIT	2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) G05B 2219/2639 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 10/0631 (20130101) G06Q 50/06 (20130101) Original (OR) Class Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/54 (20130101)
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10282869 — Few-view image reconstruction

US 10282869	Champley
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Kyle Champley (Walnut Creek, California)
ABSTRACT	A CT image reconstruction system is provided that provides a solution to a few-view problem by generating a 3D image from measurements and a forward projection matrix for a CT scan of an object that tends to minimize streaks and other artifacts. The system initially receives measurements and a forward projection matrix for the CT scan. The system during an initial stage generates an initial 3D image based on various constraints so that (1) the reconstruction of the initial 3D image can be perform quickly and (2) the difference between the measurements and the forward projection of the initial 3D image has significantly lower contrast and high frequency content as compared the measurements themselves. The system then during a final stage applies an iterative algorithm to reconstruct the 3D image with the 3D image initialized to the initial 3D image at the beginning of the iterative algorithm.
FILED	Wednesday, December 28, 2016
APPL NO	15/392985
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image Data Processing or Generation, in General G06T 11/003 (20130101) Original (OR) Class G06T 17/10 (20130101) G06T 2210/41 (20130101)
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10283225 — Thermoacoustic enhancements for nuclear fuel rods

US 10283225	Garrett et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)	The Penn State Research Foundation (University Park, Pennsylvania); U.S. Department of Energy (Washington, District of Columbia)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania); U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S)	Steven L. Garrett (State College, Pennsylvania); James A. Smith (Idaho Falls, Idaho); Dale K. Kotter (Shelley, Idaho)
ABSTRACT	A nuclear thermoacoustic device includes a housing defining an interior chamber and a portion of nuclear fuel disposed in the interior chamber. A stack is disposed in the interior chamber and has a hot end and a cold end. The stack is spaced from the portion of nuclear fuel with the hot end directed toward the portion of nuclear fuel. The stack and portion of nuclear fuel are positioned such that an acoustic standing wave is produced in the interior chamber. A frequency of the acoustic standing wave depends on a temperature in the interior chamber.
FILED	Friday, March 31, 2017
APPL NO	15/475655
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/22 (20130101) G01K 11/26 (20130101) Nuclear Reactors G21C 3/16 (20130101) G21C 17/102 (20130101) G21C 17/112 (20130101) Original (OR) Class Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/005 (20130101) G21F 5/06 (20130101) G21F 9/28 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/40 (20130101)
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10283341 — Microscale mass spectrometry systems, devices and related methods

US 10283341	Ramsey
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	John Michael Ramsey (Chapel Hill, North Carolina)
ABSTRACT	Mass spectrometry systems or assemblies therefore include an ionizer that includes at least one planar conductor, a mass analyzer with a planar electrode assembly, and a detector comprising at least one planar conductor. The ionizer, the mass analyzer and the detector are attached together in a compact stack assembly. The stack assembly has a perimeter that bounds an area that is between about 0.01 mm²to about 25 cm²and the stack assembly has a thickness that is between about 0.1 mm to about 25 mm.
FILED	Friday, February 24, 2017
APPL NO	15/441702
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/10 (20130101) H01J 49/0022 (20130101) H01J 49/424 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49117 (20150115)
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10283475 — Power module assembly with dual substrates and reduced inductance

US 10283475	Ward et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) Office of Fossil Energy and Carbon Management (FECM) National Energy Technology Laboratory (NETL)
APPLICANT(S)	GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan)
ASSIGNEE(S)	GM Global Technology Operations LLC (Detroit, Michigan)
INVENTOR(S)	Terence G. Ward (Waterford, Michigan); Constantin C. Stancu (Auburn Hills, Michigan); Marko Jaksic (Rochester Hills, Michigan)
ABSTRACT	A power module assembly has a first substrate including a first layer, second layer and a third layer. The first layer is configured to carry a switch current flowing in a first direction. A second substrate is operatively connected to the first substrate and includes a fourth layer, fifth layer and a sixth layer. A conductive joining layer connects the third layer of the first substrate and the fourth layer of the second substrate. The conductive joining layer may be a first sintered layer. The third layer of the first substrate, the first sintered layer and the fourth layer of the second substrate are configured to function together as a unitary conducting layer carrying the switch current in a second direction substantially opposite to the first direction. The net inductance is reduced by a cancellation effect of the switch current going in opposite directions.
FILED	Wednesday, December 14, 2016
APPL NO	15/378154
ART UNIT	2815 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/528 (20130101) H01L 23/5226 (20130101) H01L 23/53214 (20130101) H01L 23/53228 (20130101) H01L 24/27 (20130101) Original (OR) Class H01L 24/32 (20130101) H01L 24/33 (20130101) H01L 24/40 (20130101) H01L 24/48 (20130101) H01L 24/73 (20130101) H01L 24/83 (20130101) H01L 25/50 (20130101) H01L 25/072 (20130101) H01L 25/0655 (20130101) H01L 2224/8309 (20130101) H01L 2224/8384 (20130101) H01L 2224/8484 (20130101) H01L 2224/27505 (20130101) H01L 2224/32151 (20130101) H01L 2224/32227 (20130101) H01L 2224/32245 (20130101) H01L 2224/33181 (20130101) H01L 2224/40227 (20130101) H01L 2224/40491 (20130101) H01L 2224/48227 (20130101) H01L 2224/73215 (20130101) H01L 2224/73221 (20130101) H01L 2224/73263 (20130101) H01L 2224/73265 (20130101) H01L 2225/06527 (20130101) H01L 2924/00014 (20130101)
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10283658 — Interband cascade devices

US 10283658	Yang
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S)	Rui Q. Yang (Norman, Oklahoma)
ABSTRACT	Photovoltaic (PV) and photodetector (PD) devices, comprising a plurality of interband cascade (IC) stages, wherein the IC stages comprise an absorption region with a type-I superlattice and/or a bulk semiconductor material having a band gap, the absorption region configured to absorb photons, an intraband transport region configured to act as a hole barrier, and an interband tunneling region configured to act as an electron barrier, wherein the absorption region, the intraband transport region, and the interband tunneling region are positioned such that electrons will flow from the absorption region to the intraband transport region to the interband tunneling region.
FILED	Monday, September 14, 2015
APPL NO	14/853588
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0304 (20130101) H01L 31/0725 (20130101) H01L 31/0735 (20130101) H01L 31/035236 (20130101) Original (OR) Class Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101)
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10284021 — Lighting system with induction power supply

US 10284021	Kisner et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Roger A. Kisner (Knoxville, Tennessee); Christi R. Johnson (Kingston, Tennessee); Frederick K. Reed (Oak Ridge, Tennessee)
ABSTRACT	A system for producing light is provided. The system comprises a sealed enclosure surrounding a porous graphite foam conductor which is exposed to an electromagnetic field generated by an oscillating circuit. When exposed, the foam conductor conducts induced electric current which heats the same to product light. The amount of light is controllable by changing the output of a drive circuit. The oscillating circuit comprises a first inductor and a first capacitor. The first inductor has a first terminal and a second terminal. The output of the drive circuit is controlled by turning a MOSFET OFF and ON. The MOSFET is turned ON when an integrated signal representative of a difference between a voltage proportional to the first terminal and a voltage proportional to the second terminal is between a first voltage threshold and a second voltage threshold and based on a timing signal.
FILED	Tuesday, August 14, 2018
APPL NO	16/103324
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/30 (20160201) Original (OR) Class Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/06 (20130101) H05B 6/10 (20130101) H05B 33/0815 (20130101) H05B 33/0854 (20130101) H05B 37/0218 (20130101) H05B 37/0281 (20130101)
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National Science Foundation (NSF)

10278781 — Tool exchange interface and control algorithm for cooperative surgical robots

US 10278781	Taylor et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The John Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Russell H. Taylor (Severna Park, Maryland); Marcin Arkadiusz Balicki (Baltimore, Maryland); James Tahara Handa (Baltimore, Maryland)
ABSTRACT	A system and method for tool exchange during surgery for cooperatively controlled robots comprises a tool holder for receiving a surgical tool adapted to be held by a robot and a surgeon, a tool holding element for constraining downward motion of the tool while allowing low force removal of the surgical tool from the holder, a first sensor for detecting if the surgical tool is docked within the tool holder, and a selector for automatically selecting different movements or actions of the tool holder to be performed based upon information detected by the first sensor. The system and method of the present invention provides an advantage to an often slow moving cooperative robot, by increasing the speed by which the tool holder may move in the direction away from the patient.
FILED	Monday, December 19, 2016
APPL NO	15/383931
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 34/30 (20160201) A61B 34/32 (20160201) Original (OR) Class A61B 90/06 (20160201) A61B 2017/00477 (20130101) A61B 2090/064 (20160201) A61B 2090/065 (20160201) A61B 2090/0811 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 15/0466 (20130101)
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10278883 — Systems, methods, and devices for assisting walking for developmentally-delayed toddlers

US 10278883	Walsh et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S)	Conor J. Walsh (Cambridge, Massachusetts); Eugene C. Goldfield (Sherborn, Massachusetts); Sang-Eun Song (Chestnut Hill, Massachusetts); Evelyn Park (Rolling Hills Estates, California)
ABSTRACT	In at least some aspects, the present concepts include a method of enabling rehabilitation of bodily control of a user comprising the acts of: integrating the user within a multi-module robotic system, the multi-module robotic system comprising modules of a flexible exosuit, a support module, a mobile base, or a combination thereof, applying one or more forces, cues, or a combination thereof on the user, based on one or more subtask-specific functions of the modules, to cause a developing of one or more subtasks of the bodily control, and managing control of one or more remaining subtasks of the bodily control by the modules in place of at least in part, the user while applying the one or more forces, cues, or a combination thereof.
FILED	Thursday, February 05, 2015
APPL NO	15/117034
ART UNIT	3784 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/024 (20130101) A61H 1/0244 (20130101) A61H 1/0266 (20130101) A61H 1/0277 (20130101) A61H 3/00 (20130101) Original (OR) Class A61H 3/04 (20130101) A61H 3/008 (20130101) A61H 2003/043 (20130101) A61H 2201/0107 (20130101) A61H 2201/123 (20130101) A61H 2201/1238 (20130101) A61H 2201/5007 (20130101) A61H 2201/5061 (20130101) A61H 2201/5064 (20130101) A61H 2201/5069 (20130101) A61H 2201/5071 (20130101) A61H 2201/5084 (20130101) A61H 2201/5097 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/0058 (20130101) A63B 21/152 (20130101) A63B 21/157 (20130101) A63B 21/00178 (20130101) A63B 21/00181 (20130101) A63B 21/4009 (20151001) A63B 21/4025 (20151001) A63B 24/0087 (20130101) A63B 26/003 (20130101) A63B 69/0064 (20130101) A63B 71/0054 (20130101) A63B 2022/0092 (20130101) A63B 2024/0093 (20130101) A63B 2071/025 (20130101) A63B 2071/0072 (20130101) A63B 2071/0655 (20130101) A63B 2220/16 (20130101) A63B 2220/40 (20130101) A63B 2220/51 (20130101) A63B 2220/89 (20130101) A63B 2220/803 (20130101) A63B 2225/20 (20130101) A63B 2225/50 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/003 (20130101)
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10279042 — One-step processing of hydrogels for mechanically robust and chemically desired features

US 10279042	Mayes et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Sarah Mayes (Austin, Texas); Christine Schmidt (Gainesville, Florida)
ABSTRACT	The application of a highly controlled, micron-sized, branched, porous architecture to enhance the handling properties and degradation rate of hydrogels is described in the instant invention. A previously described pattern created through one-step nucleated crystallization in a hydrogel film creates tunable mechanical properties and/or chemical stability for use in tissue engineering applications. The bulk mechanical properties and the degradation rate of the material can be tuned easily by the addition or subtraction of crystalline structure or by the addition and subtraction of backfill material, making this useful for a variety of applications. Relevant mechanical properties that can be tuned through the application of this unique porosity are moduli, elasticity, tensile strength, and compression strength. The method of the present invention can be applied to biopolymers and natural materials as well as synthetic materials.
FILED	Friday, January 23, 2015
APPL NO	14/604298
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/738 (20130101) A61K 47/36 (20130101) Original (OR) Class
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10279079 — Compositions and methods for spinal disc repair and other surgical and non-surgical indications

US 10279079	Davis et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Raphael Davis (Port Jefferson, New York); Divya Bhatnagar (Stony Brook, New York); Miriam Rafailovich (Plainview, New York)
ASSIGNEE(S)	The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S)	Raphael Davis (Port Jefferson, New York); Divya Bhatnagar (Stony Brook, New York); Miriam Rafailovich (Plainview, New York)
ABSTRACT	The present invention features, inter alia, biocompatible compositions that include a poloxamer and one or more additives such as hyaluronic acid, gelatin, fibronectin, or a peptide fragment of fibronectin. The compositions are useful in tissue repair or remodeling, including repair of an injured spinal disc, in drug delivery, in cell culture, and in inhibiting the formation of adhesions.
FILED	Thursday, July 05, 2012
APPL NO	14/129988
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/48 (20130101) Original (OR) Class A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/3834 (20130101) A61L 2400/06 (20130101) A61L 2430/38 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) C08L 71/02 (20130101) C08L 71/02 (20130101) C08L 89/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0656 (20130101)
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10280197 — Discovery of the first selective C5A receptor 2 (C5L2/C5AR2) ligands

US 10280197	Monikis et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical and Transport Systems (CTS)
APPLICANT(S)	The Regents of the University of California (Oakland, California); The Texas A and M University System (College Station, Texas); The University of Queensland (St. Lucia, Australia); University of Sheffield (Sheffield, United Kingdom)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); The Texas A and M University System (College Station, Texas); The University of Queensland (St. Lucia, Australia); The University of Sheffield (Sheffield, United Kingdom)
INVENTOR(S)	Dimitrios Monikis (Riverside, California); Christodoulos Floudas (, None); Trent Woodruff (Carindale, Australia); Matthew A. Cooper (Chapel Hill, Australia); Daniel E. Croker (Kenmore, Australia); Peter N. Monk (Sheffield, United Kingdom)
ABSTRACT	A method of selectively modulating the activity of C5a receptor 2 (C5aR2). The method includes exposing the receptor to a compound that selectively modulates C5aR2 compared to C5a receptor 1 (C5aR1). In some cases, the compound is peptide P32 or P59. Methods of recruiting β-arrestin 2 in a cell, modulating C5a-induced ERK1/2 activation in a macrophage, selectively inhibiting the release of IL-6 from a macrophage, are also provided.
FILED	Monday, October 17, 2016
APPL NO	15/295979
ART UNIT	1675 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 5/0808 (20130101) C07K 5/0812 (20130101) C07K 7/06 (20130101) Original (OR) Class
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10280204 — Electroactive biopolymer optical and electro-optical devices and method of manufacturing the same

US 10280204	Kaplan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	TUFTS UNIVERSITY (Medford, Massachusetts)
ASSIGNEE(S)	Tufts University (Medford, Massachusetts)
INVENTOR(S)	David L. Kaplan (Concord, Massachusetts); Fiorenzo Omenetto (Lexington, Massachusetts); Brian Lawrence (Minneapolis, Minnesota); Mark Cronin-Golomb (Reading, Massachusetts)
ABSTRACT	A method of manufacturing a biopolymer optical device includes providing a polymer, providing a substrate, casting the polymer on the substrate, and enzymatically polymerizing an organic compound to generate a conducting polymer between the provided polymer and the substrate. The polymer may be a biopolymer such as silk and may be modified using organic compounds such as tyrosines to provide a molecular-level interface between the provided bulk biopolymer of the biopolymer optical device and a substrate or other conducting layer via a tyrosine-enzyme polymerization. The enzymatically polymerizing may include catalyzing the organic compound with peroxidase enzyme reactions. The result is a carbon-carbon conjugated backbone that provides polymeric “wires” for use in polymer and biopolymer optical devices. An all organic biopolymer electroactive material is thereby provided that provides optical functions and features.
FILED	Thursday, February 18, 2016
APPL NO	15/046903
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/02 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0074 (20130101) B29D 11/00663 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Peptides C07K 14/43586 (20130101) Original (OR) Class Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2211/04 (20130101) D10B 2401/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/544 (20130101) G01N 33/5436 (20130101) G01N 33/54373 (20130101) G01N 33/54386 (20130101) G01N 2333/43578 (20130101) Optical Elements, Systems, or Apparatus G02B 1/04 (20130101) G02B 1/005 (20130101) G02B 1/06 (20130101) G02B 1/041 (20130101) G02B 1/045 (20130101) G02B 1/046 (20130101) G02B 5/18 (20130101) G02B 6/138 (20130101) G02B 2006/1213 (20130101) G02B 2006/12102 (20130101) G02B 2006/12104 (20130101) G02B 2006/12107 (20130101) G02B 2006/12171 (20130101)
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10280317 — Enhanced conductivity, adhesion and environmental stability of printed graphene inks with nitrocellulose

US 10280317	Hersam et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Research Laboratory (AFRL) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Mark C. Hersam (Wilmette, Illinois); Ethan B. Secor (Evanston, Illinois); Theodore Z. Gao (Evanston, Illinois)
ABSTRACT	Graphene ink compositions comprising nitrocellulose and related methods of use comprising either thermal or photonic annealing.
FILED	Friday, July 07, 2017
APPL NO	15/644326
ART UNIT	2853 — Printing/Measuring and Testing
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/01 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/14 (20130101) C09D 11/36 (20130101) C09D 11/037 (20130101) Original (OR) Class C09D 11/52 (20130101) C09D 11/322 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/00 (20130101)
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10280342 — Adhesive materials and methods of making and using the same

US 10280342	Waite et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Herbert J. Waite (Goleta, California); B. Kollbe Ahn (Goleta, California); Craig J. Hawker (Santa Barbara, California); Jinhwa Heo (Suwon, South Korea); Taegon Kang (Suwon, South Korea)
ABSTRACT	A compound of formula (I): can be used as a monomer for making an underwater adhesive polymer. The compound of formula (I) can be prepared using eugenol as a starting material.
FILED	Wednesday, July 30, 2014
APPL NO	14/908956
ART UNIT	1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 33/20 (20130101) C07C 33/025 (20130101) C07C 33/26 (20130101) C07C 33/30 (20130101) C07C 39/19 (20130101) C07C 39/20 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1804 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 12/24 (20130101) C08F 16/26 (20130101) C08F 30/08 (20130101) C08F 220/30 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 4/06 (20130101) C09J 125/18 (20130101) C09J 129/02 (20130101) C09J 143/04 (20130101) Original (OR) Class
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10280393 — High pressure bioreactor

US 10280393	Foustoukos
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Carnegie Institution of Washington (Washington, District of Columbia)
ASSIGNEE(S)	CARNEGIE INSTITUTION OF WASHINGTON (Washington, District of Columbia)
INVENTOR(S)	Dionysis Ioannis Foustoukos (Washington, District of Columbia)
ABSTRACT	The present invention relates generally to an integrated system, apparatus and method that allows for the continuous culturing of microorganisms under high pressure conditions and at a wide range of temperatures. More specifically, the system is configured to be gas tight and operate under aerobic or anaerobic conditions. The system is also configured to permit periodic sampling of the incubated organisms under such conditions with minimal physical/chemical disturbance inside the reactor and minimal impacts of shear forces on the collected biomass.
FILED	Friday, February 27, 2015
APPL NO	15/121732
ART UNIT	1799 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 27/00 (20130101) C12M 29/00 (20130101) C12M 33/00 (20130101) C12M 41/40 (20130101) Original (OR) Class
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10280416 — Magnetic ionic liquids, methods of making and uses thereof as solvents in the extraction and preservation of nucleic acids

US 10280416	Anderson et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The University of Toledo (Toledo, Ohio)
ASSIGNEE(S)	The University of Toledo (Toledo, Ohio)
INVENTOR(S)	Jared L. Anderson (Ames, Iowa); Omprakash Nacham (Toledo, Ohio); Kevin D. Clark (Toledo, Ohio)
ABSTRACT	Described herein are methods for making and using magnetic ionic liquid that have at least one cationic component and at least one anionic component, where at least one of the cationic components or the anionic components is a paramagnetic component. The magnetic ionic liquids are capable of manipulation by an external magnetic field.
FILED	Friday, February 19, 2016
APPL NO	15/048265
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/101 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101)
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10280431 — Acyltransferases and methods of using

US 10280431	Cahoon et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Basic Energy Sciences (BES) Energy Frontier Research Centers (EFRC) Center for Advanced Biofuel Systems (CABS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Organismal Systems (IOS) Department of Agriculture (USDA)
APPLICANT(S)	NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S)	NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S)	Edgar Cahoon (Lincoln, Nebraska); Umidjon Iskandarov (Lincoln, Nebraska); Hae Jin Kim (Lincoln, Nebraska); Jillian Collins-Silva (Lincoln, Nebraska)
ABSTRACT	Provided herein are novel acyltransferases and methods of using such novel acyltransferases in making medium-chain fatty acids.
FILED	Thursday, December 18, 2014
APPL NO	14/576135
ART UNIT	1662 — Plants
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6463 (20130101)
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10281464 — Real-time detection of water contaminants

US 10281464	Chen et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	UWM Research Foundation, Inc. (Milwaukee, Wisconsin)
ASSIGNEE(S)	UWM Research Foundation, Inc. (Milwaukee, Wisconsin)
INVENTOR(S)	Junhong Chen (Whitefish Bay, Wisconsin); Jingbo Chang (Milwaukee, Wisconsin)
ABSTRACT	Provided herein is a field-effect transistor based sensor for real-time detection of water contaminants and methods of use thereof.
FILED	Monday, August 03, 2015
APPL NO	15/500943
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/10 (20130101) C12Q 1/689 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 27/4146 (20130101) G01N 33/1826 (20130101) G01N 33/1886 (20130101) G01N 33/5438 (20130101) Original (OR) Class G01N 33/54346 (20130101) G01N 33/56916 (20130101) G01N 2333/245 (20130101)
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10281723 — Wide angle and high resolution tiled head-mounted display device

US 10281723	Cheng et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	The Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona); BEIJING INSTITUTE OF TECHNOLOGY (Beijing, China PRC)
ASSIGNEE(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); BEIJING INSTITUTE OF TECHNOLOGY (Beijing, China PRC)
INVENTOR(S)	Dewen Cheng (Beijing, China PRC); Yongtian Wang (Beijing, China PRC); Hong Hua (Tucson, Arizona)
ABSTRACT	A tiled head-mounted display device, comprising: an optical component including a plurality of prisms with free-form surfaces, each prism being a wedge prism comprising a first optical surface, a second optical surface and a third optical surface; and a display component including a plurality of micro-displays, wherein the number of the micro-displays and the number of the prisms with free-form surfaces is identical. The tiled head-mounted display device according to the present invention is compact and light, provides wide field of view and high resolution, especially for the optical tiling head-mounted display device, the exit pupil planes of each display channels are coincident, thus avoiding pupil aberration and keeping exit pupil diameter and eye clearance same as the single ocular. There is no resolution variance throughout the entire field of view, thus preventing extra trapezoid distortion. The tiled head-mounted display device according to the present invention can be readily applicable to augmented environments applications by simply adding an auxiliary free-form lens behind the free-form prism.
FILED	Monday, November 30, 2015
APPL NO	14/953563
ART UNIT	2693 — Selective Visual Display Systems
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 2027/011 (20130101) G02B 2027/0123 (20130101) G02B 2027/0147 (20130101)
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10281747 — Applications of wavelength-locking using dithering signals for microring resonators

US 10281747	Padmaraju et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Kishore Padmaraju (Endwell, New York); Keren Bergman (Princeton, New Jersey)
ABSTRACT	A low-cost, robust method for automatically tuning a coupled resonator to match a wavelength of electromagnetic radiation emitted from an applied laser source. Dithering signals are used for automatic wavelength tuning and thermal stabilization of microring resonators. The disclosed method can be applied using low-speed analog and digital circuitry, to create a complete photonic interconnection network. The methods disclosed also automatically detect, measure, and correct for resonance shift.
FILED	Thursday, July 16, 2015
APPL NO	14/800799
ART UNIT	2636 — Optical Communications
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0121 (20130101) G02F 1/0147 (20130101) Original (OR) Class G02F 1/3132 (20130101) G02F 2201/58 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0085 (20130101) H01S 5/042 (20130101) H01S 5/142 (20130101) H01S 5/0687 (20130101) H01S 5/1032 (20130101) H01S 5/06832 (20130101) H01S 5/06837 (20130101)
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10281791 — Electrochromic device having three-dimensional electrode

US 10281791	Xu
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Board of Trustees of Northern Illinois University (DeKalb, Illinois)
ASSIGNEE(S)	Board of Trustees of Northers Illinois University (DeKalb, Illinois)
INVENTOR(S)	Tao Xu (Lisle, Illinois)
ABSTRACT	An electrochromic device comprises (i) a conductive layer, (ii) an electrochromic material, on the conductive layer, (iii) an electrolyte, on the electrochromic material, and (iv) a counter-electrode, on the electrolyte. The conductive layer has a surface roughness factor (SRF) of at least 10, and the conductive layer comprises a semi-metal.
FILED	Tuesday, July 12, 2016
APPL NO	15/208402
ART UNIT	2872 — Optics
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/15 (20130101) G02F 1/153 (20130101) G02F 1/155 (20130101) Original (OR) Class G02F 1/163 (20130101) G02F 1/1521 (20130101) G02F 1/1523 (20130101) G02F 1/1525 (20130101) G02F 1/1533 (20130101) G02F 1/134309 (20130101) G02F 2001/1512 (20130101) G02F 2001/1515 (20130101) G02F 2001/1519 (20130101) G02F 2001/1555 (20130101) G02F 2001/134318 (20130101) G02F 2201/123 (20130101)
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10281986 — Methods, controllers and computer program products for accessibility to computing devices

US 10281986	Howard et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Ayanna Howard (Atlanta, Georgia); Brett Berry (Alpharetta, Georgia); Justin Nicholas Devenish (Acworth, Georgia); Po Kai Hsu (Atlanta, Georgia); Tiffany Jernigan (Bellevue, Washington); William Johnston (Washington, District of Columbia); Hae Won Park (NUSorcross Norcross, Georgia); Giancarlo Valentin (Bayamon, Puerto Rico); Siu Chuen Yau (Atlanta, Georgia)
ABSTRACT	Methods of providing user accessibility to an electronic device are provided. Methods include receiving a physical input via at least one user input device in a user interface, generating, in the user interface, a sensor output signal responsive to receiving the physical input from the user, and interpreting the sensor output signal as a gesture input signal that that is received by the electronic device. The gesture input signal is operative to cause the electronic device to perform a function corresponding to a gesture that is physically applied to the electronic device.
FILED	Thursday, May 02, 2013
APPL NO	14/397894
ART UNIT	2694 — Selective Visual Display Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/016 (20130101) G06F 3/017 (20130101) Original (OR) Class G06F 3/0414 (20130101) G06F 3/04883 (20130101)
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10282687 — Systems and methods for managing power generation resources

US 10282687	Parvania
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Masood Parvania (Salt Lake City, Utah)
ABSTRACT	An optimal operating configuration for a power system may be derived from a continuous-time model of generation and ramping constraints of power generation units available within the power system. The optimal operating configuration may be leveraged to calculate a valuation metric for power generated by the power generating units. The valuation metric may include costs incurred by the power generating units due to ramping events. In addition, incremental generation and ramping cost metrics may be used to identify power generation units to use in responding to short-term load variations. Power generating units may be selected based, at least in part, on the incremental ramping costs of the power generating units.
FILED	Friday, December 30, 2016
APPL NO	15/396363
ART UNIT	2116 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Systems for Regulating Electric or Magnetic Variables G05F 1/66 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06312 (20130101) G06Q 10/06314 (20130101) Original (OR) Class G06Q 50/06 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/008 (20130101) H02J 3/32 (20130101) H02J 2003/007 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 40/76 (20130101) Y02E 60/76 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/82 (20151101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/54 (20130101) Y04S 10/545 (20130101) Y04S 40/22 (20130101) Y04S 50/10 (20130101)
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10282833 — Gate-level mapping of integrated circuits using multi-spectral imaging

US 10282833	Adato et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Science Foundation (NSF)
APPLICANT(S)	Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S)	Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S)	Ronen Adato (Boston, Massachusetts); Ajay Joshi (Lexington, Massachusetts); M. Selim Unlu (Newton, Massachusetts); Bennett B. Goldberg (Chicago, Illinois)
ABSTRACT	Optical verification testing of an IC includes obtaining images of the IC by, for each image: (i) illuminating the IC with excitation light, wherein the excitation light corresponds to a respective specific optical excitation of a predefined spectrum of optical excitations (e.g., wavelength spectrum); and (ii) detecting scattered light from the IC in response to the specific optical excitation. For each of a set of sub-regions of the images, the respective sub-region is mapped to at least one of (i) a specific sub-unit of a predefined set of sub-units (e.g., gates) of the IC and (ii) a null result, thereby creating a representation of a detected layout of the IC as an arrangement of the sub-units. The representation can be used to verify that an as-fabricated layout is consistent with an as-designed layout, to detect unauthorized modifications of the IC structure.
FILED	Wednesday, November 30, 2016
APPL NO	15/771493
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) G01N 21/956 (20130101) Electric Digital Data Processing G06F 17/5081 (20130101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) G06T 7/0004 (20130101) G06T 7/0006 (20130101) Original (OR) Class G06T 2207/10152 (20130101) G06T 2207/20021 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30148 (20130101)
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10282899 — Systems, methods and, media for simulating deformations of nonlinear elastic bodies

US 10282899	Mitchell et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Nathan M. Mitchell (Madison, Wisconsin); Eftychios D. Sifakis (Verona, Wisconsin); Michael S. Doescher (Madison, Wisconsin)
ABSTRACT	In accordance with some embodiments, systems, methods and media for simulating deformation of an elastic body are provided. In some embodiments, a method comprises: determining for each macroblock, a stiffness matrix K_iof a portion of a model of a non-linear elastic solid partitioned into cells; converting K_iinto block form to include a submatrix K_I_i_I_ifor nodes between internal cells of a first macroblock; determining at least a portion of K_I_i_I_i⁻¹; receiving input corresponding to force applied to cells of the model; determining displacements of exterior nodes of the first macroblock using the input and the portion of K_I_i_I_i⁻¹; determining displacements of interior nodes of the first macroblock using the input and the displacements of exterior nodes; determining updated positions of the cells based on the displacements of the exterior nodes; and, causing the model to be presented using the updated positions.
FILED	Monday, July 10, 2017
APPL NO	15/645770
ART UNIT	2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Image Data Processing or Generation, in General G06T 15/005 (20130101) G06T 17/205 (20130101) Original (OR) Class G06T 19/20 (20130101) G06T 2215/16 (20130101) G06T 2219/2021 (20130101)
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10283658 — Interband cascade devices

US 10283658	Yang
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S)	Rui Q. Yang (Norman, Oklahoma)
ABSTRACT	Photovoltaic (PV) and photodetector (PD) devices, comprising a plurality of interband cascade (IC) stages, wherein the IC stages comprise an absorption region with a type-I superlattice and/or a bulk semiconductor material having a band gap, the absorption region configured to absorb photons, an intraband transport region configured to act as a hole barrier, and an interband tunneling region configured to act as an electron barrier, wherein the absorption region, the intraband transport region, and the interband tunneling region are positioned such that electrons will flow from the absorption region to the intraband transport region to the interband tunneling region.
FILED	Monday, September 14, 2015
APPL NO	14/853588
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0304 (20130101) H01L 31/0725 (20130101) H01L 31/0735 (20130101) H01L 31/035236 (20130101) Original (OR) Class Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101)
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10283689 — Phononic metamaterials comprising atomically disordered resonators

US 10283689	Hussein
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	The Regents of the University of Colorado a body corporate (Denver, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S)	Mahmoud I. Hussein (Superior, Colorado)
ABSTRACT	Phononic metamaterials and methods for reducing the group velocities and the thermal conductivity in at least partially crystalline base material are provided, such as for thermoelectric energy conversion. In one implementation, a method for reducing thermal conductivity through an at least partially crystalline base material is provided. In another implementation, a phononic metamaterial structure is provided. The phononic metamaterial structure in this implementation includes: an at least partially crystalline base material configured to allow a plurality of phonons to move to provide thermal conduction through the base material; and at least one disordered (e.g., amorphous) material coupled (e.g., as an inclusion, extending substructure, outer matrix, a coating to heavy inner inclusion, etc.) to the at least partially crystalline base material. The at least one disordered material is configured to generate at least one vibration mode by the oscillation of at least one atom within the disordered material to interact with the plurality of phonons moving within the base material and slow group velocities of at least a portion of the interacting phonons and reduce thermal conductivity through the base material.
FILED	Monday, October 10, 2016
APPL NO	15/289921
ART UNIT	2811 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 1/005 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/04 (20130101) G10K 11/172 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/04 (20130101) Original (OR) Class H01L 35/14 (20130101) H01L 35/26 (20130101) H01L 35/30 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/24 (20130101) H03H 9/2405 (20130101) H03H 2009/155 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/833 (20130101) Y10S 977/932 (20130101)
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10284339 — Differential MIMO transceiver

US 10284339	Sayeed et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) National Science Foundation (NSF)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Akbar M. Sayeed (Madison, Wisconsin); John H. Brady (Madison, Wisconsin)
ABSTRACT	A receiver detects a plurality of information symbols. A first signal and a second signal are received from a first transmitted signal and a second transmitted signal, respectively, transmitted by a first plurality of antennas and received by a second plurality of antennas connected to the receiver. The second signal is received after the first signal. The receiver spatially filters the first signal using a spatial filter matrix. The receiver computes a conjugate of the first filtered signal to define a conjugate first signal, and spatially filters a second signal using the spatial filter matrix. The receiver computes a Hadamard product of the first filtered signal and the conjugate first signal to define a differential measurement signal. The receiver detects the plurality of information symbols from the differential measurement signal.
FILED	Monday, November 27, 2017
APPL NO	15/823018
ART UNIT	2631 — Digital Communications
CURRENT CPC	Transmission H04B 7/0413 (20130101) H04B 7/0617 (20130101) H04B 7/0626 (20130101) H04B 7/0697 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0618 (20130101) Original (OR) Class H04L 25/03 (20130101)
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10284395 — Time-based decision feedback equalization

US 10284395	Chiu et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S)	Po-Wei Chiu (Minneapolis, Minnesota); Somnath Kundu (Hillsboro, Oregon); Hyung-il Kim (Woodbury, Minnesota)
ABSTRACT	A time-based decision feedback equalizer (TB-DFE) circuit may include a voltage-to-time converter configured to convert a communication signal into a time-based signal. A timing of when an edge of the time-based signal occurs is indicative of a voltage level of the communication signal. The circuit may include a plurality of delay circuits arranged to process the time-based signal in series to generate a delay data signal. The delay circuits may adjust the timing of when the edge of the time-based signal occurs, and a corresponding time delay introduced by each of the delay circuits may be based on a respective weighting factor applied to one or more samples of an output digital signal previously generated by the TB-DFE circuit. A phase detector may compare a timing of an edge of the delay data signal with a reference clock signal and generate the output digital signal based on the comparison.
FILED	Wednesday, November 08, 2017
APPL NO	15/806901
ART UNIT	2632 — Digital Communications
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0041 (20130101) H04L 7/0087 (20130101) H04L 25/03031 (20130101) H04L 25/03057 (20130101) Original (OR) Class H04L 2025/03471 (20130101) H04L 2025/03783 (20130101)
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10284885 — Method and apparatus for redacting video for compression and identification of releasing party

US 10284885	Borras et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	NOA, INC. (Miami Beach, Florida)
ASSIGNEE(S)	NOA, Inc. (Miami Beach, Florida)
INVENTOR(S)	Jaime A. Borras (Miramar, Florida); Siddharth Roheda (Raleigh, North Carolina)
ABSTRACT	A method and system for protecting video and image files processes from original files to detect skin tones of persons appearing in the media. Pixels determined to contain skin tones are blurred or blacked out, and the pixel locations and their original color values are stored in a metadata file. The metadata file is encrypted and stored with the redacted video file. Thereafter, when an authorized person wants to see an unredacted version of the video, the system decrypts the metadata and reconstituted the video, replacing the redacted pixels with their original color values, and inserting a unique watermark into the video that identifies the requesting person. The watermarked video is then provided to the requesting person.
FILED	Monday, January 30, 2017
APPL NO	15/419440
ART UNIT	2436 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/16 (20130101) G06F 2221/0737 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) G06K 9/00744 (20130101) G06K 9/6278 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0428 (20130101) Pictorial Communication, e.g Television H04N 21/84 (20130101) H04N 21/2347 (20130101) H04N 21/2351 (20130101) Original (OR) Class H04N 21/2353 (20130101) H04N 21/2743 (20130101) H04N 21/8358 (20130101) H04N 21/23418 (20130101) H04N 21/26613 (20130101) H04N 21/41407 (20130101) H04N 21/41422 (20130101) H04N 21/234381 (20130101)
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National Aeronautics and Space Administration (NASA)

10278568 — Endoscope and system and method of operation thereof

US 10278568	Manohara et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Harish M. Manohara (Glendora, California); Anna Liao (Calgary, Canada); Youngsam Bae (Placentia, California); Hrayr Karnig Shahinian (Beverly Hills, California)
ASSIGNEE(S)
INVENTOR(S)	Harish M. Manohara (Glendora, California); Anna Liao (Calgary, Canada); Youngsam Bae (Placentia, California); Hrayr Karnig Shahinian (Beverly Hills, California)
ABSTRACT	An endoscope includes a rigid section having an opening situated between two ends. The endoscope also includes a handle for manipulation and at the first end. An image capturing device is near the second end and is configured to provide a first view when pointed in a first direction. The image capturing device is moved with respect to a longitudinal axis of the rigid section in response to a movement of an extension portion of a shaft located in the opening and operatively coupling the handle and a first base part resulting from the manipulation of the handle. A fixing member is rigidly coupled to the rigid section and pivotably coupled to the first base part at a second pivot portion of the first base part, and a second base part is pivotably connected to the fixing member at a pivot portion of the second base part.
FILED	Monday, January 23, 2017
APPL NO	15/413307
ART UNIT	3779 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/05 (20130101) A61B 1/00039 (20130101) A61B 1/00045 (20130101) A61B 1/045 (20130101) Original (OR) Class A61B 1/051 (20130101) A61B 1/00183 (20130101) A61B 1/0676 (20130101) A61B 1/0684 (20130101) A61B 1/3132 (20130101)
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10280964 — Nut insert with reduced stress

US 10280964	O'Coin
FUNDED BY	National Aeronautics and Space Administration (NASA) Johnson Space Center (JSC)
APPLICANT(S)	HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina)
ASSIGNEE(S)	Hamilton Sundstrand Corporation (Charlotte, North Carolina)
INVENTOR(S)	James R. O'Coin (Somers, Connecticut)
ABSTRACT	A nut insert body includes an outer periphery and an aperture formed with threads. The threads are centered on a thread axis. The outer periphery of the nut insert body is curved about a curve axis defined about an axis having at least a component extending in a perpendicular direction from the thread axis. A component receiving a nut insert is also disclosed.
FILED	Monday, February 15, 2016
APPL NO	15/043668
ART UNIT	3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Separation B01D 53/00 (20130101) B01D 53/26 (20130101) B01D 2257/80 (20130101) B01D 2257/504 (20130101) B01D 2259/4575 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 37/04 (20130101) F16B 37/041 (20130101) F16B 37/122 (20130101) Original (OR) Class
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10281422 — Displacement current phase tomography for imaging of lossy medium

US 10281422	Marashdeh et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	Tech4Imaging LLC (Columbus, Ohio); Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S)	TECH4IMAGING LLC (Columbus, Ohio); OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
INVENTOR(S)	Qussai Mohammad Marashdeh (Columbus, Ohio); Geoffrey A. Legg (Tewksbury, Massachusetts); Christopher Edward Zuccarelli (Columbus, Ohio); Fernando Teixeira (Columbus, Ohio); Cagdas Gunes (Columbus, Ohio); Burak Gurlek (Istanbul, Turkey); Shah Chowdhury (Columbus, Ohio); Benjamin Straiton (Pataskala, Ohio); Joshua Sines (Hilliard, Ohio)
ABSTRACT	A system and method for Displacement Current Phase Tomography. The present system invention obtains a linear relationship between mutual displacement current from a sensor (output current of the measuring electrode terminals) and the area (or volume) of an object to be imaged in the imaging domain. The system uses capacitance sensors and utilizes the phase of the measured current, in addition to the amplitude, to reconstruct an image.
FILED	Monday, September 12, 2016
APPL NO	15/262565
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/22 (20130101) Original (OR) Class
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10281430 — Identification and characterization of remote objects by electric charge tunneling, injection, and induction, and an erasable organic molecular memory

US 10281430	Generazio
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NASA (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Administratior of NASA (Washington, District of Columbia)
INVENTOR(S)	Edward R. Generazio (Yorktown, Virginia)
ABSTRACT	Various embodiments provide methods to identify and characterize remote objects by use of electric charge distributions generated by charge tunneling, charge injection, and charge induction. Various embodiments may use selective electrostatic charging to change the electrostatic potential throughout volumes for identification and characterization. In various embodiments, objects of interest may be selectively charged by tunneling, injection, and induction of electrical charges or free carriers. Tunneled, injected, and induced charges may migrate to sites or locations internal to volumes to yield electrostatic potential differences and electrostatic fields. In various embodiments, variations in the electrostatic potential created by the presence of the tunneled, injected, and induced charges may be quantitatively measured to identify and characterize remote objects.
FILED	Wednesday, July 12, 2017
APPL NO	15/647640
ART UNIT	2827 — Semiconductors/Memory
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/60 (20130101) Original (OR) Class Static Stores G11C 13/02 (20130101)
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10281907 — Residual mode filters

US 10281907	Frost et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as Represented By the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	United Stated of America as Represented by the Administrator of the NASA (Washington, District of Columbia)
INVENTOR(S)	Susan A. Frost (Cupertino, California); Mark J. Balas (Laramie, Wyoming)
ABSTRACT	Methods and systems for controlling a physical system (plant) are disclosed. The plant is modeled as a linear, finite-dimensional system having a state vector, a control input vector, a plant output vector, and a disturbance vector comprising disturbances having known basis functions and unknown amplitudes. An adaptive control law is used with separate adaptive gains for an error vector associated with the plant output vector, and the disturbance vector, plus a fixed gain for a disturbance estimator. The adaptive control law is operable to adjust the control input vector so as to minimize the error vector. The plant includes modes which are not Almost Strictly Positive Real (ASPR).
FILED	Friday, April 22, 2016
APPL NO	15/136691
ART UNIT	2117 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/41885 (20130101) Original (OR) Class G05B 2219/39215 (20130101) G05B 2219/39233 (20130101)
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10282841 — Bioinformatic analysis of vascular patterning

US 10282841	Parsons-Wingerter et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Administrator of the NASA (Washington, District of Columbia)
INVENTOR(S)	Patricia A. Parsons-Wingerter (Los Altos, California); Mary B. Vickerman (Cleveland, Ohio)
ABSTRACT	Biometric analysis of vascular patterning may be performed in 3D and 2D as an integrative biomarker of complex molecular and mechanical signaling. The vascular patterning may facilitate the coordination of essentially unlimited numbers of bioinformatics dimensions for specific molecular and other co-localizations with spatiotemporal dimensions of vascular morphology. The vascular patterning may also apply geometric principles of translational versus rotational principles for vascular branching to support the transformation of VESGEN 2D to VESGEN 3D.
FILED	Monday, July 18, 2016
APPL NO	15/213175
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/1241 (20130101) Image Data Processing or Generation, in General G06T 7/0014 (20130101) Original (OR) Class G06T 7/408 (20130101) G06T 2207/10024 (20130101) G06T 2207/20072 (20130101) G06T 2207/30104 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 45/00 (20190201)
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10283759 — Silicon-based anode and method for manufacturing the same

US 10283759	Yushin et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Glenn Research Center (GLENN)
APPLICANT(S)	CLEMSON UNIVERSITY RESEARCH FOUNDATION (Clemson, South Carolina); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
ASSIGNEE(S)	Clemson University Research Foundation (Clemson, South Carolina); Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Gleb Nikolayevich Yushin (Atlanta, Georgia); Igor Luzinov (Clemson, South Carolina); Bogdan Zdyrko (Clemson, South Carolina); Alexandre Magasinski (Atlanta, Georgia)
ABSTRACT	A silicon-based anode comprising silicon, a carbon coating that coats the surface of the silicon, a polyvinyl acid that binds to at least a portion of the silicon, and vinylene carbonate that seals the interface between the silicon and the polyvinyl acid. Because of its properties, polyvinyl acid binders offer improved anode stability, tunable properties, and many other attractive attributes for silicon-based anodes, which enable the anode to withstand silicon cycles of expansion and contraction during charging and discharging.
FILED	Monday, January 09, 2017
APPL NO	15/401841
ART UNIT	1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) H01M 4/386 (20130101) H01M 4/0404 (20130101) H01M 4/0419 (20130101) H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 4/1395 (20130101) Original (OR) Class H01M 2004/027 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/54 (20151101)
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Department of Agriculture (USDA)

10279366 — Method and device to detect clogged nozzles

US 10279366	Larbi et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Arkansas State University Jonesboro (State University, Arkansas)
ASSIGNEE(S)	Arkansas State University Jonesboro (State University, Arkansas)
INVENTOR(S)	Peter Ako Larbi (Jonesboro, Arkansas); Chin Nee Vong (Columbia, Missouri)
ABSTRACT	The nozzle clog detection device, system, and method detect if a liquid flows through a nozzle via conduction of electricity. The clog detector provides an open circuit at an opening between two conductors. The two conductors are placed in the flow path of a liquid flowing from a nozzle. The liquid from the nozzle conducts electricity. The liquid flowing through the opening between the conductors closes the circuit. An alert system notifies the user whether liquid is flowing through the nozzle. The system detects flow of liquid from multiple nozzles and identifies the nozzles from which liquid flows. A break in the circuit at the opening between the conductors indicates that the liquid is not flowing sufficiently enough to close the circuit.
FILED	Friday, March 02, 2018
APPL NO	15/911061
ART UNIT	2683 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC	Planting; Sowing; Fertilising A01C 23/047 (20130101) Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 7/0042 (20130101) A01M 7/0089 (20130101) A01M 21/043 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 12/008 (20130101) B05B 15/50 (20180201) Original (OR) Class Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/64 (20130101)
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10280294 — Nanofibril-polymer composites

US 10280294	Gardner et al.
FUNDED BY	Department of Agriculture (USDA) Agricultural Research Service (ARS) Cooperative State Research, Education, and Extension Service (CSREES)
APPLICANT(S)	University of Maine System Board of Trustees (Bangor, Maine)
ASSIGNEE(S)	University of Maine System Board of Trustees (Bangor, Maine)
INVENTOR(S)	Douglas J. Gardner (Brewer, Maine); Yousoo Han (Bangor, Maine); Yucheng Peng (Evansville, Indiana)
ABSTRACT	The present invention provides, among other things, compositions comprising nanofibrils, at least one maleic-anhydride (MA) copolymer and at least one matrix polymer, and methods of making such compositions. The provided methods and compositions allow for the production of composites with unexpectedly superior properties including improved impact resistance, tensile modulus of elasticity, tensile strength, and flexural modulus of elasticity as compared to previously known composites. In some embodiments, the present invention provides methods including the steps of providing cellulose nanofibrils, associating the cellulose nanofibrils with a maleic-anhydride (MA) copolymer to form a nanofibril-MA copolymer blend, preparing the nanofibril-MA copolymer blend for addition to a matrix polymer, and forming a composite by associating the nanofibril-MA copolymer blend with the matrix polymer, wherein the amount of cellulose nanofibrils in the composite is between 3% and 50% by weight of the composite.
FILED	Thursday, July 17, 2014
APPL NO	14/905349
ART UNIT	1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/003 (20130101) B29C 45/0001 (20130101) B29C 64/165 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/08 (20130101) B29K 2023/14 (20130101) B29K 2073/00 (20130101) B29K 2201/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/226 (20130101) C08J 5/005 (20130101) C08J 2323/12 (20130101) C08J 2451/06 (20130101) Compositions of Macromolecular Compounds C08L 1/00 (20130101) C08L 1/00 (20130101) C08L 1/00 (20130101) C08L 1/04 (20130101) C08L 1/04 (20130101) C08L 23/10 (20130101) C08L 23/10 (20130101) C08L 23/12 (20130101) Original (OR) Class C08L 51/06 (20130101) C08L 51/06 (20130101) C08L 51/06 (20130101) C08L 51/06 (20130101) C08L 2205/16 (20130101) C08L 2205/16 (20130101) C08L 2205/16 (20130101) C08L 2310/00 (20130101) C08L 2310/00 (20130101) C08L 2310/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10280397 — Feeder-free method for culture of bovine and porcine spermatogonial stem cells

US 10280397	Oatley et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Washington State University (Pullman, Washington)
ASSIGNEE(S)	Washington State University (Pullman, Washington)
INVENTOR(S)	Jon Michael Oatley (Pullman, Washington); Melissa Joan Oatley (Pullman, Washington)
ABSTRACT	The present invention relates to the production and culture of undifferentiated spermatogonial stem cells that can be maintained long term and are feeder free. The resultant feeder-free populations can be used in any of a number of protocols including the generation of progeny bulls. The present invention includes novel methods required for the successful enrichment of bovine spermatogonial stem cells, novel cell lines and other components used for the same, as well as the resultant stem cell compositions.
FILED	Thursday, August 25, 2016
APPL NO	15/247564
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 2207/12 (20130101) A01K 2227/101 (20130101) A01K 2227/108 (20130101) A01K 2267/02 (20130101) Diagnosis; Surgery; Identification A61B 17/425 (20130101) Veterinary Instruments, Implements, Tools, or Methods A61D 19/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/52 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/061 (20130101) Original (OR) Class C12N 5/0602 (20130101) C12N 5/0603 (20130101) C12N 5/0656 (20130101) C12N 5/0683 (20130101) C12N 15/873 (20130101) C12N 2500/05 (20130101) C12N 2500/24 (20130101) C12N 2500/25 (20130101) C12N 2500/32 (20130101) C12N 2500/38 (20130101) C12N 2500/44 (20130101) C12N 2500/46 (20130101) C12N 2500/84 (20130101) C12N 2500/90 (20130101) C12N 2501/13 (20130101) C12N 2501/21 (20130101) C12N 2501/115 (20130101) C12N 2501/125 (20130101) C12N 2501/727 (20130101) C12N 2502/13 (20130101) C12N 2502/246 (20130101) C12N 2510/04 (20130101) C12N 2533/90 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10280431 — Acyltransferases and methods of using

US 10280431	Cahoon et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Basic Energy Sciences (BES) Energy Frontier Research Centers (EFRC) Center for Advanced Biofuel Systems (CABS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Organismal Systems (IOS) Department of Agriculture (USDA)
APPLICANT(S)	NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S)	NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S)	Edgar Cahoon (Lincoln, Nebraska); Umidjon Iskandarov (Lincoln, Nebraska); Hae Jin Kim (Lincoln, Nebraska); Jillian Collins-Silva (Lincoln, Nebraska)
ABSTRACT	Provided herein are novel acyltransferases and methods of using such novel acyltransferases in making medium-chain fatty acids.
FILED	Thursday, December 18, 2014
APPL NO	14/576135
ART UNIT	1662 — Plants
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6463 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10282955 — Forest fire fuel heat transfer sensor

US 10282955	Linn et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S)	Rodman Linn (Los Alamos, New Mexico); Scott Goodrick (Athens, Georgia); Joseph John O'Brien (Athens, Georgia)
ABSTRACT	A heat transfer sensor includes a support body, a first thermocouple probe, a second thermocouple probe, and a third thermocouple probe. Each thermocouple probe is mounted to the support body and includes a hollow cylinder, a thermocouple, and an insulator. The thermocouple is mounted to an interior of the associated hollow cylinder and is configured to generate a first voltage based on a temperature of the associated hollow cylinder. The insulator is mounted between the associated hollow cylinder and the top wall. The first hollow cylinder has an emissivity ≤0.25. The second hollow cylinder has an emissivity ≥0.75. The third thermocouple probe has an emissivity that is >0.25 and <0.75 or measures a temperature of an environment surrounding the support body. A convective heat transfer and an incident radiation are computed using the first and second voltage and either the third voltage or the air temperature.
FILED	Thursday, May 18, 2017
APPL NO	15/598599
ART UNIT	2683 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC	Fire-fighting A62C 3/0271 (20130101) Regulating or Controlling Combustion F23N 2029/10 (20130101) F23N 2029/16 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 17/005 (20130101) Original (OR) Class G08B 17/08 (20130101) G08B 17/12 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

National Security Agency (NSA)

10282119 — Methods of pairwise combinations in streaming data

US 10282119	Burkhardt
FUNDED BY	National Security Agency (NSA)
APPLICANT(S)	The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Director, National Security Agency (Washington, District of Columbia)
INVENTOR(S)	Paul Burkhardt (North Potomac, Maryland)
ABSTRACT	A method is disclosed for pairwise combination of data elements of an input data stream. Steps are performed for each data element. A master controller reads the data from the stream and increments a counter. A register is instantiated, holding at least two words of memory and corresponding to the counter, by updating a register map and sending a message to a target processor via a logical pathway. The message instructs the target processor to create the register in local memory, including first and second memory locations, and an index corresponding to a value i. The target processor copies the data into the first memory location. For every other register corresponding to a value less than i, the other register copies the data into the second memory location and outputs a unique pair, constructed from the data elements stored at the first and second memory locations, to a database.
FILED	Thursday, March 17, 2016
APPL NO	15/072483
ART UNIT	2194 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0629 (20130101) Original (OR) Class G06F 3/0683 (20130101) G06F 9/30098 (20130101) G06F 16/24568 (20190101)
VIEW PATENT	@ USPTO: Full Text PDF

10282636 — System, method, and recording medium for efficient cohesive subgraph identification in entity collections for inlier and outlier detection

US 10282636	Cheng et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Yu Cheng (Ossining, New York); Sharathchandra U. Pankanti (Darien, Connecticut); Nalini K. Ratha (White Plains, New York)
ABSTRACT	A similarity detection system receiving a plurality of input entities, the system including a cohesive subgraph identification device configured to calculate, based on attributes of the plurality of input entities, a first parameter and a second parameter based on the first parameter, and further configured to identify a plurality of subgraphs from the second parameter and a subgraph correlation tracking and clustering device configured to determine a relationship between different subgraphs based on a similarity factor between the second parameter and the plurality of subgraphs.
FILED	Tuesday, October 24, 2017
APPL NO	15/791662
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00228 (20130101) G06K 9/00442 (20130101) G06K 9/00677 (20130101) G06K 9/6215 (20130101) Original (OR) Class G06K 9/6218 (20130101) G06K 9/6296 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10284363 — Serial transmitter with feed forward equalizer

US 10284363	Dickson et al.
FUNDED BY	National Security Agency (NSA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Timothy O. Dickson (Danbury, Connecticut); Mounir Meghelli (Tarrytown, New York)
ABSTRACT	A serial transmitter that outputs one symbol every unit interval (UI) from a data source is presented. The serial transmitter includes a serial output port that outputs one symbol every unit interval (UI) from a data source. The serial transmitter also includes a plurality of driver segments that jointly drive the serial output port. Each driver segment is configured to use one of N phases of a sampling clock to serialize and transmit data from the data source. Different sets of the driver segments are configured to use different phases of the sampling clock for serializing and transmitting data, the sampling clock being a half-rate clock having a period of two UI.
FILED	Thursday, November 02, 2017
APPL NO	15/802012
ART UNIT	2632 — Digital Communications
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 7/044 (20130101) H04L 7/0058 (20130101) H04L 7/0091 (20130101) H04L 7/0338 (20130101) Original (OR) Class Selecting H04Q 2213/03 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Homeland Security (DHS)

10282429 — Hazardous materials incident location system and uses thereof

US 10282429	Clark
FUNDED BY	Department of Homeland Security (DHS)
APPLICANT(S)	Latissha Varina Clark (Houston, Texas)
ASSIGNEE(S)
INVENTOR(S)	Latissha Varina Clark (Houston, Texas)
ABSTRACT	Provided herein are systems for locating one or more hazardous material incidents, for example, a petrochemical incident, in a geographical area of interest. The system generally comprises electronic device with at least a processor, a memory and a display coupled to the processor and at least one network connection; and a user interactive tool coupled to the electronic device. Particularly, the interactive tool or interactive mapping tool comprises activatable widgets in an interface, databases accessible by the widgets and a mapping application and displayable interactive base map. Also provided is a method and utilizing the system to locate hazardous material incidents by activating the widgets, querying the databases and displaying incident data retrieved from the databases on the base map. Further provided is a non-transitory machine-readable storage device comprising processor-executable instructions to perform the method.
FILED	Wednesday, August 06, 2014
APPL NO	14/453198
ART UNIT	3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Electric Digital Data Processing G06F 17/30241 (20130101) Original (OR) Class G06F 17/30545 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10284353 — Subsurface radio

US 10284353	Shope et al.
FUNDED BY	Department of Homeland Security (DHS) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Sandia Research Corporation (Mesa, Arizona)
ASSIGNEE(S)	Sandia Research Corporation (Mesa, Arizona)
INVENTOR(S)	Steven Michael Shope (Mesa, Arizona); Paul Raymond Jorgenson (Phoenix, Arizona)
ABSTRACT	A method for subsurface radio communication includes transmitting voice data through a subsurface environment, by a transmitter of a radio transceiver. The voice data is received through the subsurface environment, by a receiver of the radio transceiver. A transceiver frequency of the radio transceiver is changed to an optimal transceiver frequency in response to a change to the subsurface environment. The transceiver frequency is one of a transmit frequency of the transmitter and a receive frequency of the receiver. A first impedance of a subwavelength antenna is matched to a second impedance of the transceiver in response to a difference between the first impedance and the second impedance exceeding an impedance mismatch value. The subwavelength antenna has a radiating length less than a transceiver wavelength of the radio transceiver operating in free-space at a maximum of the transceiver frequency.
FILED	Friday, October 28, 2016
APPL NO	15/338207
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/04 (20130101) H01Q 1/30 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/006 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Central Intelligence Agency (CIA)

10280787 — Monitoring rotating machinery using radio frequency probes

US 10280787	Pratt et al.
FUNDED BY	Central Intelligence Agency (CIA) Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Thomas G. Pratt (Niles, Michigan); Jeffrey G. Mueller (South Bend, Indiana); Robert D. Kossler (South Bend, Indiana); Neil Dodson (South Bend, Indiana); Scott C. Morris (Granger, Indiana)
ASSIGNEE(S)	University of Notre Dame Du Lac (South Bend, Indiana)
INVENTOR(S)	Thomas G. Pratt (Niles, Michigan); Jeffrey G. Mueller (South Bend, Indiana); Robert D. Kossler (South Bend, Indiana); Neil Dodson (South Bend, Indiana); Scott C. Morris (Granger, Indiana)
ABSTRACT	Systems and methods for monitoring rotating machinery are disclosed. Transmitter and receiver antennas can be provided with access to the rotating machinery. At least one receiver signal resulting from at least one transmitter signal that has propagated through a portion of the rotating machinery can be obtained. A first signal pair can be formed from a first receiver signal and a first transmitter signal, or from first and second receiver signals obtained from spatially-separated receiver antennas, or from first and second receiver signals which are attributable to different transmitter signals. Amplitude and phase information of a plurality of frequency components for each signal in the first signal pair can be determined. A set of comparison values for the first signal pair can be determined by comparing respective frequency component phases or respective frequency component amplitudes. A characteristic of the rotating machinery can then be analyzed using the comparison values.
FILED	Monday, November 09, 2015
APPL NO	14/936523
ART UNIT	2631 — Digital Communications
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 21/003 (20130101) Original (OR) Class Transmission H04B 1/40 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Veterans Affairs (DVA)

10280465 — Biomarkers for predicting relapse in multiple sclerosis

US 10280465	Rus et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	The United States of America as represented by the Department of Veteran Affairs, Department of Veterans Affairs (Washington, District of Columbia); University of Maryland, Baltimore (Baltimore, Maryland)
ASSIGNEE(S)	UNIVERSITY OF MARYLAND, BALTIMORE (Baltmore, Maryland); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S)	Horea G. Rus (Catonsville, Maryland); Cosmin A. Tegla (Bronx, New York)
ABSTRACT	Methods of determining relapse in subjects having relapsing-remitting multiple sclerosis (RRMS) and predicting their response to glatiramer acetate (GA) using the biomarkers SIRT1, RGC-32, FasL and IL-21 are presented.
FILED	Tuesday, December 22, 2015
APPL NO	14/978772
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2333/54 (20130101) G01N 2333/525 (20130101) G01N 2333/978 (20130101) G01N 2800/54 (20130101) G01N 2800/285 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Environmental Protection Agency (EPA)

10278395 — Functionalized environmentally benign nanoparticles

US 10278395	Velev et al.
FUNDED BY	Environmental Protection Agency (EPA)
APPLICANT(S)	North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S)	North Carolina State University (Raleigh, North Carolina)
INVENTOR(S)	Orlin D. Velev (Raleigh, North Carolina); Alexander P. Richter (Raleigh, North Carolina)
ABSTRACT	This invention is directed to the preparation and applications of internally and/or externally functionalized environmentally benign nanoparticles (EbNPs), which are produced by a three step procedure: (1) synthesis of native EbNPs, (2) functionalization with active agents, and (3) additional surface property customization via one or more modifier(s).
FILED	Monday, March 10, 2014
APPL NO	14/202259
ART UNIT	1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/28 (20130101) A01N 25/34 (20130101) A01N 59/16 (20130101) Original (OR) Class A01N 59/16 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Office of the Director of National Intelligence (ODNI)

10283696 — Architecture for coupling quantum bits using localized resonators

US 10283696	Dial et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Office of the Director of National Intelligence (ODNI) Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Oliver Dial (Yorktown Heights, New York); Jay M. Gambetta (Yorktown Heights, New York); Douglas T. McClure, III (Rye, New York); Matthias Steffen (Cortlandt Manor, New York)
ABSTRACT	A technique relates a superconducting microwave cavity. An array of posts has different heights in the cavity, and the array supports a localized microwave mode. The array of posts includes lower resonant frequency posts and higher resonant frequency posts. The higher resonant frequency posts are arranged around the lower resonant frequency posts. A first plate is opposite a second plate in the cavity. One end of the lower resonant frequency posts is positioned on the second plate so as to be electrically connected to the second plate. Another end of the lower resonant frequency posts in the array is open so as not to form an electrical connection to the first plate. Qubits are connected to the lower resonant frequency posts in the array of posts, such that each of the qubits is physically connected to one or two of the lower resonant frequency posts in the array of posts.
FILED	Monday, November 23, 2015
APPL NO	14/949248
ART UNIT	2827 — Semiconductors/Memory
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/14 (20130101) H01L 39/025 (20130101) H01L 39/2493 (20130101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/205 (20130101) H01P 7/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

10284353 — Subsurface radio

US 10284353	Shope et al.
FUNDED BY	Department of Homeland Security (DHS) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Sandia Research Corporation (Mesa, Arizona)
ASSIGNEE(S)	Sandia Research Corporation (Mesa, Arizona)
INVENTOR(S)	Steven Michael Shope (Mesa, Arizona); Paul Raymond Jorgenson (Phoenix, Arizona)
ABSTRACT	A method for subsurface radio communication includes transmitting voice data through a subsurface environment, by a transmitter of a radio transceiver. The voice data is received through the subsurface environment, by a receiver of the radio transceiver. A transceiver frequency of the radio transceiver is changed to an optimal transceiver frequency in response to a change to the subsurface environment. The transceiver frequency is one of a transmit frequency of the transmitter and a receive frequency of the receiver. A first impedance of a subwavelength antenna is matched to a second impedance of the transceiver in response to a difference between the first impedance and the second impedance exceeding an impedance mismatch value. The subwavelength antenna has a radiating length less than a transceiver wavelength of the radio transceiver operating in free-space at a maximum of the transceiver frequency.
FILED	Friday, October 28, 2016
APPL NO	15/338207
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/04 (20130101) H01Q 1/30 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/006 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

United States Postal Service (USPS)

10281931 — System and method of control of electronic parcel lockers

US 10281931	Irwin et al.
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S)	United States Postal Service (Washington, District of Columbia)
INVENTOR(S)	Donald E. Irwin (Fredericksburg, Virginia); Nan K. McKenzie (Garrett Park, Maryland); William A. Tartal (Baltimore, Maryland); Victoria K. Stephen (Burke, Virginia); Michael J. Amato (Reston, Virginia)
ABSTRACT	A system, apparatus, and method for use in delivery of items to a storage unit. The storage unit can include one or several storage receptacles and a control unit that controls and monitors the status of the one or several storage receptacles. The storage unit may be included in a storage unit system that can include one or several storage units and a central control unit. The central control unit can communicate with the one or several storage units, and can receive status and availability updates from the one or several storage units.
FILED	Thursday, June 29, 2017
APPL NO	15/638244
ART UNIT	2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC	Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 1/0485 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 3/00 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/00 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0836 (20130101) Coin-freed or Like Apparatus G07F 7/08 (20130101) G07F 17/10 (20130101) G07F 17/12 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

10282500 — Efficient modeling of electromagnetic properties of an assembly

US 10282500	Van et al.
FUNDED BY
APPLICANT(S)	Tri Van (Stanton, California); George Antilla (Redondo Beach, California); Owen Cupp (Fullerton, California)
ASSIGNEE(S)	NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia); APPLIED RESEARCH ASSOCIATES, INC. (Dayton, Ohio)
INVENTOR(S)	Tri Van (Stanton, California); George Antilla (Redondo Beach, California); Owen Cupp (Fullerton, California)
ABSTRACT	Systems and methods are provided for modeling electromagnetic properties of an assembly. The system includes a modeling component configured to divide the assembly into a plurality of subdomains, with each subdomain representing a three-dimensional volume of the assembly, and determine a set of standard elemental basis functions for each subdomain, such that a linear combination of elemental basis functions represents the electromagnetic properties of a portion of the geometry of the subdomain. A synthetic function generator is configured to generate a set of synthetic “entire-domain” basis functions for each subdomain from its set of elemental basis functions. A response characterization component is configured to determine the electromagnetic properties of the assembly from the sets of synthetic basis functions for each subdomain and an excitation matrix representing simulated incident electrical and magnetic stimulation to the assembly.
FILED	Monday, October 17, 2016
APPL NO	15/295532
ART UNIT	2128 — AI & Simulation/Modeling
CURRENT CPC	Electric Digital Data Processing G06F 17/5018 (20130101) Original (OR) Class G06F 2217/16 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

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Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190507.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital