FedInvent™ Patents

Patent Details for Tuesday, May 14, 2019

This page was updated on Monday, March 27, 2023 at 05:48 AM GMT

Department of Health and Human Services (HHS)

10285702 — Bioresorbable biopolymer anastomosis devices

US 10285702	Jose et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Trustees of Tufts College (Medford, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	Trustees of Tufts College (Medford, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S)	Rodrigo R. Jose (Medford, Massachusetts); Waseem K. Raja (Medford, Massachusetts); David L. Kaplan (Concord, Massachusetts); Ahmed Ibrahim (Brookline, Massachusetts); Samuel Lin (Dover, Massachusetts); Abdurrahman Abdurrob (Winchester, Massachusetts)
ABSTRACT	A bioresorbable drug-eluting biopolymer suture-free blood vessel anastomosis devices can be deployed to join two blood vessels and resorbed by the body over a predetermined time period after the blood vessel has become joined. The anastomosis device can include a hollow tube that is inserted interconnect the two vessels to be jointed. A non-piercing suture is wrapped around the vessel to secure the anastomosis. The anastomosis device can include hollow tube that extends along an axis from a first end to a second end. The ends can be fitted with elements that facilitate mechanical attachment of the vessel to the anastomosis device and provide for a secure seal.
FILED	Thursday, April 24, 2014
APPL NO	14/785047
ART UNIT	3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/11 (20130101) Original (OR) Class A61B 2017/00004 (20130101) A61B 2017/00526 (20130101) A61B 2017/00778 (20130101) A61B 2017/00858 (20130101) A61B 2017/00893 (20130101) A61B 2017/1107 (20130101) A61B 2017/1132 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/502 (20130101) A61L 27/507 (20130101)
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10285813 — Tensioning device and methods for use

US 10285813	Kocaturk
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Ozgur Kocaturk (Rockville, Maryland)
ABSTRACT	A tensioning device is provided comprising a locking device. The locking device comprises a locking enclosure comprising a groove and a locking pin comprising teeth. The tensioning device further comprises a suture comprising first and second portions. The first and second portions of the suture and the locking pin are positioned within the groove of the locking enclosure and the locking pin is movable within the groove between a first, outer position in which the teeth are disengaged from the suture so that the locking device is movable along the first and second portions of the suture and a second, inner position in which the teeth are engaged with the suture so that the locking device is not movable along the suture. Methods for treating mitral valve regurgitation are also provided.
FILED	Tuesday, December 01, 2015
APPL NO	14/956238
ART UNIT	3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/0487 (20130101) A61B 2017/0409 (20130101) A61B 2017/0451 (20130101) A61B 2017/0496 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/246 (20130101) Original (OR) Class A61F 2/2445 (20130101) A61F 2/2466 (20130101) Belts, Cables, or Ropes, Predominantly Used for Driving Purposes; Chains; Fittings Predominantly Used Therefor F16G 11/14 (20130101) F16G 11/101 (20130101) F16G 11/106 (20130101)
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10285855 — Capsulotomy device with suction cup compression chamber

US 10285855	Keller
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Christopher Guild Keller (El Cerrito, California)
ASSIGNEE(S)	Mynosys Cellular Devices, Inc. (Fremont, California)
INVENTOR(S)	Christopher Guild Keller (El Cerrito, California)
ABSTRACT	A surgical device and procedure are provided for smoothly and easily accessing tissue to perform microsurgery, including a capsulotomy of a lens capsule of an eye. The device includes a handpiece with a tip for insertion into an incision in the cornea of the eye. A sliding element is disposed within the handpiece and a suction cup is mounted to the sliding element. The sliding element can be translated to move the suction cup into and out of the handpiece. A compression mechanism associated with the suction cup and the handpiece compresses the suction cup for deployment through the tip of the handpiece. The suction cup can expand inside the anterior chamber into a cutting position on the lens capsule. A cutting element mounted to the suction cup is used to cut a portion of the lens capsule and to remove the portion from the eye.
FILED	Monday, August 06, 2012
APPL NO	14/237029
ART UNIT	3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 18/1402 (20130101) A61B 2018/1266 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0079 (20130101) A61F 9/00754 (20130101) Original (OR) Class
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10285943 — Aptamer bioconjugate drug delivery device

US 10285943	Bloembergen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Steven Bloembergen (Okemos, Michigan); Ian J. McLennan (Burlington, Canada); Nathan Jones (Hamilton, Canada); Ryan Wagner (Kitchener, Canada); Aareet Krsna Ganesh Shermon (Waterloo, Canada); Abdel Rahman Elsayed (Waterloo, Canada); Juewen Liu (Kitchener, Canada)
ASSIGNEE(S)	GreenMark Biomedical Inc. (East Lansing, Michigan)
INVENTOR(S)	Steven Bloembergen (Okemos, Michigan); Ian J. McLennan (Burlington, Canada); Nathan Jones (Hamilton, Canada); Ryan Wagner (Kitchener, Canada); Aareet Krsna Ganesh Shermon (Waterloo, Canada); Abdel Rahman Elsayed (Waterloo, Canada); Juewen Liu (Kitchener, Canada)
ABSTRACT	A delivery device for an active agent comprises nanoparticles based on a biopolymer such as starch. The delivery device may also be in the form of an aptamer-biopolymer-active agent conjugate wherein the aptamer targets the device for the treatment of specific disorders. The nanoparticles may be made by applying a high shear force in the presence of a crosslinker. The particles may be predominantly in the range of 50-150 nm and form a colloidal dispersion of crosslinked hydrogel particles in water. The biopolymer may be functionalized. The aptamer may be conjugated directly to the cross-linked biopolymers. The active agent may be a drug useful for the treatment of cancer. The delivery device survives for a period of time in the body sufficient to allow for the sustained release of a drug and for the transportation and uptake of the conjugate into targeted cells. However, the biopolymer is biocompatible and resorbable.
FILED	Friday, December 02, 2011
APPL NO	13/990278
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/145 (20130101) Original (OR) Class A61K 9/1676 (20130101) A61K 9/5161 (20130101) A61K 31/704 (20130101) A61K 47/36 (20130101) A61K 47/549 (20170801) A61K 47/6939 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Polysaccharides; Derivatives Thereof C08B 31/003 (20130101) C08B 31/185 (20130101) C08B 33/00 (20130101) C08B 35/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/906 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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10285949 — Modified alginates for cell encapsulation and cell therapy

US 10285949	Vegas et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); The Chidren's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S)	Arturo J. Vegas (Cambridge, Massachusetts); Minglin Ma (Ithaca, New York); Kaitlin M. Bratlie (Ames, Iowa); Daniel G. Anderson (Framingham, Massachusetts); Robert S. Langer (Newton, Massachusetts)
ABSTRACT	Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for the encapsulation and transplantation of cells. Also disclosed are high throughput methods for the characterizing the biocompatibility and physiochemical properties of modified alginate polymers.
FILED	Tuesday, July 12, 2016
APPL NO	15/208192
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/5036 (20130101) Original (OR) Class A61K 9/5161 (20130101) A61K 35/39 (20130101) A61K 45/06 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101)
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10285952 — Nanoparticles leverage biological membranes to target pathogens for disease treatment and diagnosis

US 10285952	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Liangfang Zhang (San Diego, California); Che-Ming Jack Hu (San Diego, California)
ABSTRACT	Provided are methods, combinations and pharmaceutical compositions for treating or preventing an infection in a subject using a nanoparticle comprising a) an inner core comprising a non-cellular material, and b) an outer surface comprising a cellular membrane configured for adhesion of a pathogen that causes said infection. Exemplary infection includes infection caused by a virus, bacterium, fungus, or protozoan.
FILED	Tuesday, January 19, 2016
APPL NO	15/000110
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 9/5094 (20130101) A61K 9/5153 (20130101) A61K 9/5176 (20130101) Original (OR) Class A61K 31/4709 (20130101) A61K 35/17 (20130101) A61K 35/18 (20130101) A61K 35/19 (20130101) A61K 49/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/587 (20130101) G01N 33/56905 (20130101) G01N 2333/445 (20130101)
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10285960 — Autoimmune disorder treatment using RXR agonists

US 10285960	Chandraratna et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Complementary and Integrative Health (NCCIH) National Cancer Institute (NCI)
APPLICANT(S)	IO Therapeutics, Inc. (Santa Ana, California); Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S)	IO Therapeutics, Inc. (Santa Ana, California)
INVENTOR(S)	Roshantha A. Chandraratna (San Juan Capistrano, California); Ethan Dmitrovsky (Hanover, New Hampshire); Elizabeth Nowak (West Lebanon, New Hampshire); Randolph Noelle (Plainfield, New Hampshire)
ABSTRACT	The present specification provides RXR agonist compounds, compositions comprising such RXR agonists, and methods using such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection as well as use of such RXR agonists to manufacture a medicament and use of such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection.
FILED	Wednesday, November 02, 2016
APPL NO	15/341969
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0073 (20130101) A61K 31/47 (20130101) A61K 31/192 (20130101) Original (OR) Class A61K 31/201 (20130101) A61K 31/216 (20130101) A61K 31/343 (20130101) A61K 31/353 (20130101) A61K 31/4704 (20130101) Technologies for Adaptation to Climate Change Y02A 50/414 (20180101)
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10285962 — Glutarate compounds for treating ischemia-reperfusion injuries

US 10285962	Huang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Complementary and Integrative Health (NCCIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Jing Huang (Los Angeles, California); Xudong Fu (Los Angeles, California); Xiang Yin (Los Angeles, California); Mansoureh Eghbali (Los Angeles, California); Jingyuan Li (Los Angeles, California); Karen Reue (Torrance, California); Laurent Vergnes (Los Angeles, California)
ABSTRACT	Disclosed herein are methods of preventing, inhibiting, reducing, or treating ischemia and reperfusion injury to tissues with glutarate compounds such as α-ketoglutarate.
FILED	Sunday, April 30, 2017
APPL NO	15/582748
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/194 (20130101) Original (OR) Class A61K 31/198 (20130101) A61K 31/365 (20130101) A61K 31/365 (20130101) A61K 31/616 (20130101) A61K 31/616 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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10285976 — 4-methylumbelliferone treatment for immune modulation

US 10285976	Bollyky et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Benaroya Research Institute at Virginia Mason (Seattle, Washington); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California); BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON (Seattle, Washington)
INVENTOR(S)	Paul L. Bollyky (Palo Alto, California); Nadine Nagy (Seattle, Washington); Thomas Wight (Seattle, Washington); Hedwich F. Kuipers (Palo Alto, California)
ABSTRACT	Compositions for treating autoimmune, allergic, or atopic disease comprising a compound that inhibits hyaluronan synthesis and a pharmaceutically acceptable carrier are described. In some embodiments, the compound that inhibits hyaluronan synthesis is 4-methylumbelliferone or a metabolite of 4-methylumbelliferone. Methods for treating autoimmune diabetes, multiple sclerosis and/or autoimmune demyelination, including administering to the subject a composition having a compound in an amount effective to inhibit hyaluronan synthesis in a mammalian subject, are also described.
FILED	Tuesday, August 12, 2014
APPL NO	14/911533
ART UNIT	1673 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/37 (20130101) Original (OR) Class A61K 31/7048 (20130101)
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10285978 — Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio

US 10285978	Bassler et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)	The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S)	Bonnie L. Bassler (Princeton, New Jersey); Lark J. Perez (Ewing, New Jersey); Martin F. Semmelhack (Princeton, New Jersey)
ABSTRACT	A structurally distinct and potent series of synthetic small molecule activators of Vibrio cholerae quorum sensing have been chemically synthesized. The small molecule activators reduce virulence in V. cholerae. Acyl pyrrole molecules displayed strong potency and stability, particularly 1-(1H-pyrrol-3-yl)decan-1-one.
FILED	Wednesday, November 29, 2017
APPL NO	15/825597
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/36 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) A61K 31/53 (20130101) A61K 31/401 (20130101) Original (OR) Class A61K 31/401 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 207/333 (20130101) Technologies for Adaptation to Climate Change Y02A 50/471 (20180101)
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10285986 — Compounds and anti-tumor NQO1 substrates

US 10285986	Hergenrother et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois); The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois); The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S)	Paul J. Hergenrother (Champaign, Illinois); David A. Boothman (Dallas, Texas); Joseph S. Bair (Albany, California); Rahul Palchaudhuri (Cambridge, Massachusetts); Elizabeth I. Parkinson (Champaign, Illinois)
ABSTRACT	Compositions comprising Formula (I) can be selectively lethal toward a variety of different cancer cell types. The compositions are useful for the management, treatment, control, or adjunct treatment of diseases, where the selective lethality is beneficial in chemotherapeutic therapy.
FILED	Friday, March 23, 2018
APPL NO	15/933671
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/4745 (20130101) Original (OR) Class A61K 45/06 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6561 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/26 (20130101)
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10286001 — Use of purified 2′-fucosyllactose, 3-fucosyllactose and lactodifucotetraose as prebiotics

US 10286001	Newburg et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Glycosyn LLC (Woburn, Massachusetts); Trustees of Boston College (Chesnut Hill, Massachusetts)
ASSIGNEE(S)	Glycosyn LLC (Waltham, Massachusetts); Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S)	David S. Newburg (Newtonville, Massachusetts); John M. McCoy (Reading, Massachusetts); Massimo Merighi (Somerville, Massachusetts); Matthew Ian Heidtman (Brighton, Massachusetts); Zhuoteng Yu (Brighton, Massachusetts)
ABSTRACT	The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
FILED	Monday, January 30, 2017
APPL NO	15/419241
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 2/52 (20130101) A23L 33/10 (20160801) A23L 33/21 (20160801) A23L 33/28 (20160801) A23L 33/40 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/702 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 3/06 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) Y02A 50/481 (20180101)
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10286010 — Methods of treating neurodegenerative conditions

US 10286010	Johe et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Neuralstem, Inc. (Germantown, Maryland); The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	Neuralstem, Inc. (Rockville, Maryland)
INVENTOR(S)	Karl K. Johe (Hallandale Beach, Florida); Thomas G. Hazel (North Potomac, Maryland); Martin Marsala (San Diego, California); Osamu Kakinohana (San Diego, California)
ABSTRACT	The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.
FILED	Thursday, July 27, 2017
APPL NO	15/661281
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0085 (20130101) A61K 35/30 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0623 (20130101) C12N 2501/11 (20130101) C12N 2501/113 (20130101) C12N 2501/115 (20130101) C12N 2501/148 (20130101)
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10286011 — Compositions and methods for transplantation of colon microbiota

US 10286011	Sadowsky et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S)	Michael J. Sadowsky (Roseville, Minnesota); Alexander Khoruts (Golden Valley, Minnesota); Alexa R. Weingarden (St. Paul, Minnesota); Matthew J. Hamilton (Burnsville, Minnesota)
ABSTRACT	The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
FILED	Friday, May 12, 2017
APPL NO	15/594087
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 9/0053 (20130101) A61K 9/1617 (20130101) A61K 9/1623 (20130101) A61K 35/24 (20130101) A61K 35/24 (20130101) A61K 35/37 (20130101) Original (OR) Class A61K 35/74 (20130101) A61K 35/74 (20130101) A61K 35/741 (20130101) A61K 35/742 (20130101) A61K 45/06 (20130101) A61K 47/08 (20130101) A61K 47/26 (20130101) A61K 2035/11 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) Y02A 50/475 (20180101)
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10286012 — Compositions and methods for transplantation of colon microbiota

US 10286012	Sadowsky et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S)	Michael J. Sadowsky (Roseville, Minnesota); Alexander Khoruts (Golden Valley, Minnesota); Alexa R. Weingarden (St. Paul, Minnesota); Matthew J. Hamilton (Burnsville, Minnesota)
ABSTRACT	The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
FILED	Friday, May 12, 2017
APPL NO	15/594319
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 9/0053 (20130101) A61K 9/1617 (20130101) A61K 9/1623 (20130101) A61K 35/24 (20130101) A61K 35/24 (20130101) A61K 35/37 (20130101) Original (OR) Class A61K 35/74 (20130101) A61K 35/74 (20130101) A61K 35/741 (20130101) A61K 35/742 (20130101) A61K 45/06 (20130101) A61K 47/08 (20130101) A61K 47/26 (20130101) A61K 2035/11 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) Y02A 50/475 (20180101)
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10286016 — Compositions and methods for treating gonorrhea

US 10286016	Kim et al.
FUNDED BY	Department of Defense (DOD) Uniformed Services University of the Health Sciences (USUHS) Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE HENRY M. JACKSON FOUDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland)
INVENTOR(S)	Won Jong Kim (Tucson, Arizona); Maria Auxilio Rendón-Espinosa (Tucson, Arizona); Magdalene Yh So (Tucson, Arizona); Maira Goytia (Atlanta, Georgia); Ann Jerse (Bethesda, Maryland); Dustin Higashi (Notre Daem, Indiana)
ABSTRACT	The present invention relates to compositions and methods for preventing and/or treating gonorrhea. In particular, the present invention provides compositions comprising an effective amount of a commensal species of Neisseria (e.g., an effective amount of an extract of a commensal species of Neisseria), wherein such compositions are capable of inhibiting the growth of Neisseria gonorrhoeae.
FILED	Wednesday, September 02, 2015
APPL NO	15/508409
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/02 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 14/22 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101)
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10286039 — Compositions and methods for treating neutropenia

US 10286039	Wu
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Children's Hospital Los Angeles (Los Angeles, California)
ASSIGNEE(S)	Children's Hospital Los Angeles (Los Angeles, California)
INVENTOR(S)	Lingtao Wu (Rancho Palos Verdes, California)
ABSTRACT	The invention relates methods of using a retinoid agonist and a G-CSF or an analog thereof to treat, prevent, reduce the likelihood of having, reduce the severity of and/or slow the progression of a condition in a subject. The retinoid agonist and the G-CSF or the analog thereof may be provided in a single composition or in separate compositions. A therapeutically effective amount of the retinoid agonist and the G-CSF or the analog thereof may be administered to the subject concurrently or sequentially. Conditions treatable with the methods and compositions include but are not limited to various forms of neutropenia and microbial infections. The invention also relates to methods for determining the efficacy of the treatments described herein.
FILED	Wednesday, February 18, 2015
APPL NO	15/119339
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 31/69 (20130101) A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) A61K 35/15 (20130101) A61K 38/193 (20130101) Original (OR) Class A61K 38/193 (20130101) A61K 45/06 (20130101) A61K 2035/124 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0642 (20130101) C12N 2501/22 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/84 (20130101) G01N 2800/52 (20130101)
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10286042 — Methods for the treatment of neurological disorders and diseases using FNDC5

US 10286042	Spiegelman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S)	Bruce M. Spiegelman (Waban, Massachusetts); Christiane D. Wrann (Boston, Massachusetts)
ABSTRACT	The invention provides methods for identifying, assessing, preventing, and treating neurological disorders and diseases using Fndc5 and modulators of Fndc5 expression or activity.
FILED	Wednesday, October 01, 2014
APPL NO	15/026381
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/39 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 48/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) G01N 33/5058 (20130101) G01N 33/6896 (20130101) G01N 2333/78 (20130101) G01N 2800/28 (20130101) G01N 2800/52 (20130101)
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10286043 — Collagen III composition and uses

US 10286043	Volk
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Susan Volk (Media, Pennsylvania)
ABSTRACT	The invention includes methods of suppressing cancer metastasis and local recurrence in a subject. In one aspect, the method comprises removing the tumor by surgery; and implanting a composition of the invention to the site of the primary tumor. In another aspect, the method comprises implanting a composition of the invention to a cancerous site. The composition comprises a pharmaceutically effective amount of collagen type III.
FILED	Tuesday, January 19, 2016
APPL NO	15/544960
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0024 (20130101) A61K 9/70 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/34 (20130101) Peptides C07K 14/78 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/00 (20130101) D01F 6/66 (20130101) D01F 6/625 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2509/00 (20130101)
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10286049 — Tumor vaccination in combination with hematopoietic cell transplantation for cancer therapy

US 10286049	Strober et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Samuel Strober (Stanford, California); Alexander Filatenkov (Menlo Park, California)
ABSTRACT	In one aspect, the present invention provides a method for treating cancer comprising tumor cell vaccination in combination with hematopoietic and immune cell transplantation. In some embodiments, the method involves autologous tumor cell vaccination prior to autologous hematopoietic and immune cell transplantation. In another aspect, the present invention provides a method of purifying tumor cells from a subject in preparation for vaccination.
FILED	Monday, November 09, 2015
APPL NO	14/921862
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) A61K 35/17 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 41/00 (20130101) A61K 2039/5152 (20130101) A61K 2039/55522 (20130101) A61K 2039/55561 (20130101) A61K 2300/00 (20130101)
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10286050 — Multi-epitope TARP peptide vaccine and uses thereof

US 10286050	Wood et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Lauren V. Wood (Bethesda, Maryland); Jay A. Berzofsky (Bethesda, Maryland); Brenda D. Roberson (Frederick, Maryland); Masaki Terabe (Potomac, Maryland)
ABSTRACT	Immunogenic T cell receptor γ alternate reading frame protein (TARP) peptide compositions that include multiple epitopes of the TARP protein are described. The disclosed compositions can be used for the treatment of TARP-expressing cancers, such as prostate cancer, breast cancer and mesothelioma. In some embodiments, the TARP peptide compositions disclosed herein include sets of overlapping TARP peptides that each have a length of about 15 to about 25 amino acids, and comprise about 5 to about 15 amino acids that are identical to at least another overlapping peptide in the set. In particular examples, the combination of the overlapping TARP peptides in the set encompasses the complete amino acid sequence of human TARP. The multi-epitope peptide compositions described herein include both CD4 and CD8 epitopes, a feature that is important for eliciting CD4⁺ T cell and CD8⁺ T cell, as well as humoral, immune responses.
FILED	Friday, December 12, 2014
APPL NO	15/102996
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/572 (20130101) A61K 2039/575 (20130101) A61K 2039/5154 (20130101)
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10286057 — Cyclic HIV-1 Env V3 glycopeptide immunogens

US 10286057	Haynes et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	DUKE UNIVERSITY (Durham, North Carolina); SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York); DANA-FARBER CANCER INSTITUTE, INC (Boston, Massachusetts)
ASSIGNEE(S)	Duke University (Durham, North Carolina); Sloan-Kettering Institute for Cancer Research (New York, New York); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S)	Barton F. Haynes (Durham, North Carolina); Hua-xin Liao (Durham, North Carolina); Samuel Danishefsky (New York, New York); Peter Park (New York, New York); Joseph Sodroski (Boston, Massachusetts); Baptiste Aussedat (New York, New York); Yusuf Vohra (New York, New York)
ABSTRACT	The present invention relates, in general, to human immunodeficiency virus (HIV), and, in particular, to a vaccine for HIV-1, comprising synthetic V3 glycopeptides, and to methods of making and using same.
FILED	Tuesday, April 15, 2014
APPL NO	14/784501
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 39/21 (20130101) A61K 2039/545 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/001 (20130101) C07K 14/005 (20130101) C07K 14/162 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16034 (20130101) C12N 2740/16134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) G01N 2333/16 (20130101)
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10286058 — Vaccines against HPV and HPV-related diseases

US 10286058	Oh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	BAYLOR RESEARCH INSTITUTE (Dallas, Texas)
ASSIGNEE(S)	Baylor Research Institute (Dallas, Texas)
INVENTOR(S)	SangKon Oh (Baltimore, Maryland); Sandra Zurawski (Midlothian, Texas); Gerard Zurawski (Midlothian, Texas)
ABSTRACT	Embodiments relate to novel vaccines against human papillomavirus (HPV) and HPV-related diseases, including multiple types of cancers. The HPV vaccines are composed of anti-human dendritic cell (DC) surface receptor antibodies, including CD40, and E6/7 proteins of HPV 16 and 18. The technology described is not limited to making vaccines against HPV16- and HPV18-related diseases and can be applied to making vaccines carrying E6/7 from any type of HPV. The HPV vaccines described can target DCs, major and professional antigen presenting cells (APCs), and can induce and activate potent HPV E6/7-specific and strong CD4+ and CD8+ T cell responses. The HPV vaccines can be used for the prevention of HPV infection and HPV-related diseases as well as for the treatment of HPV-related diseases, including cancers.
FILED	Tuesday, January 13, 2015
APPL NO	15/111357
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 39/395 (20130101) A61K 39/3955 (20130101) A61K 39/39541 (20130101) A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/505 (20130101) A61K 2039/585 (20130101) A61K 2039/6056 (20130101) A61K 2039/55511 (20130101) Peptides C07K 14/005 (20130101) C07K 16/2878 (20130101) C07K 2317/24 (20130101) C07K 2317/56 (20130101) C07K 2317/565 (20130101) C07K 2319/74 (20130101) C07K 2319/91 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/20034 (20130101)
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10286063 — Modified H7 hemagglutinin glycoprotein of the Influenza A/Shanghai/2/2013 H7 sequence

US 10286063	De Groot et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	EpiVax, Inc. (Providence, Rhode Island)
ASSIGNEE(S)	EPIVAX, INC. (Providence, Rhode Island)
INVENTOR(S)	Anne S De Groot (Providence, Rhode Island); William D Martin (Cumberland, Rhode Island)
ABSTRACT	The present invention is directed to a sequence modification of the H7 hemagglutinin glycoprotein of the Influenza A/Shanghai/2/2013 H7 sequence together with vaccines derived therefrom. In addition, the invention further comprises method for improving the efficacy of vaccine antigens by modifying T cell epitopes.
FILED	Monday, May 02, 2016
APPL NO	15/571040
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/57 (20130101) A61K 2039/575 (20130101) A61K 2039/5258 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/00034 (20130101) C12N 2760/16122 (20130101) C12N 2760/16123 (20130101) C12N 2760/16134 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101)
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10286064 — Cationic lipid vaccine compositions and methods of use

US 10286064	Johnson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	PDS BIOTECHNOLOGY CORPORATION (Lawrenceburg, Indiana); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SEC. OF THE DEPT. OF HEALTH AND HUMAN SERVICE (Rockville, Maryland)
ASSIGNEE(S)	PDS Biotechnology Corporation (North Brunswick, New Jersey); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SEC. OF THE DEPT. OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia)
INVENTOR(S)	Kenya Johnson (Mason, Ohio); Eric Jacobson (Cincinnati, Ohio); Frank Bedu-Addo (Bethel, Connecticut); Mikayel Mkrtichyan (Rockville, Maryland); Samir N. Khleif (Silver Spring, Maryland)
ABSTRACT	The present disclosure provides vaccine compositions comprising at least one adjuvant and at least one therapeutic factor. The disclosure also provides methods of reducing an immune suppressor cell population in a mammal, methods of augmenting an immune response in a mammal, and methods of treating a disease in a mammal utilizing the vaccine compositions.
FILED	Thursday, June 13, 2013
APPL NO	14/407419
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/0005 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/585 (20130101) A61K 2039/55511 (20130101) A61K 2039/55516 (20130101) A61K 2039/55522 (20130101) A61K 2039/55555 (20130101) A61K 2039/55566 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/20034 (20130101)
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10286065 — Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds

US 10286065	Dickey et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas); Pulmotect, Inc. (Houston, Texas); Baylor College of Medicine (Houston, Texas)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); BAYLOR COLLEGE OF MEDICINE (Houston, Texas); PULMOTECT, INC. (Houston, Texas)
INVENTOR(S)	Burton Dickey (Houston, Texas); Scott Evans (Bellaire, Texas); Brian Gilbert (Houston, Texas); Diane Markesich (Houston, Texas); Brenton Scott (Houston, Texas); Michael Tuvim (Houston, Texas)
ABSTRACT	Embodiments are directed to compositions and methods for treating viral infections.
FILED	Monday, September 21, 2015
APPL NO	14/860205
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0078 (20130101) A61K 31/24 (20130101) A61K 31/215 (20130101) A61K 31/215 (20130101) A61K 31/7056 (20130101) A61K 31/7056 (20130101) A61K 38/05 (20130101) A61K 38/05 (20130101) A61K 38/06 (20130101) A61K 38/06 (20130101) A61K 38/07 (20130101) A61K 38/07 (20130101) A61K 38/08 (20130101) A61K 38/08 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/55561 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/388 (20180101)
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10286066 — Artificial antigen presenting cells and uses thereof

US 10286066	Riley et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	James L. Riley (Downingtown, Pennsylvania); Carl H. June (Merion Station, Pennsylvania); Robert H. Vonderheide (Merion Station, Pennsylvania); Nicole Aqui (Philadelphia, Pennsylvania); Megan M. Davis (Nuangola, Pennsylvania)
ABSTRACT	The invention relates to novel artificial antigen presenting cells (aAPCs). The aAPC comprises at least one stimulatory ligand and at least one co-stimulatory ligand where the ligands each specifically bind with a cognate molecule on a T cell of interest, thereby mediating expansion of the T cell. The aAPC of the invention can further comprise additional molecules useful for expanding a T cell of interest. The aAPC of the invention can be used as an “off the shelf’ APC that can be readily designed to expand a T cell of interest. Also, the aAPC of the invention can be used identify the stimulatory, co-stimulatory, and any other factors that mediate growth and expansion of a T cell of interest. Thus, the present invention provides powerful tools for development of novel therapeutics where activation and expansion of a T cell can provide a benefit.
FILED	Wednesday, December 21, 2016
APPL NO	15/387199
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 47/642 (20170801) A61K 2035/124 (20130101) A61K 2039/5154 (20130101) A61K 2039/5158 (20130101) A61K 2039/55522 (20130101) A61K 2039/55527 (20130101) A61K 2039/55533 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) C12N 5/0635 (20130101) C12N 5/0636 (20130101) C12N 5/0694 (20130101) C12N 15/86 (20130101) C12N 2501/23 (20130101) C12N 2501/51 (20130101) C12N 2501/515 (20130101) C12N 2501/599 (20130101) C12N 2502/99 (20130101) C12N 2510/00 (20130101) C12N 2740/15043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/56972 (20130101)
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10286068 — Methods to improve induction of IgA antibodies by vaccines

US 10286068	Boyaka
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
ASSIGNEE(S)	Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S)	Prosper Boyaka (Columbus, Ohio)
ABSTRACT	A vaccine composition is disclosed that contains a vaccine antigen and a neutrophil inhibitor in amounts effective to promote an IgA response to the antigen in a subject. Also disclosed is a method for enhancing immune response to a vaccine antigen in a subject that involves co-administering to the subject the vaccine antigen and an adjuvant composition comprising a neutrophil inhibitor in an amount effective to promote an IgA response to the vaccine antigen in the subject.
FILED	Friday, April 15, 2016
APPL NO	15/566884
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 9/0019 (20130101) A61K 9/0036 (20130101) A61K 39/00 (20130101) A61K 39/07 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 39/0291 (20130101) A61K 2039/541 (20130101) A61K 2039/542 (20130101) A61K 2039/543 (20130101) A61K 2039/6037 (20130101) A61K 2039/55527 (20130101) A61K 2039/55561 (20130101) A61K 2039/55566 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) A61P 37/04 (20180101)
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10286073 — Magnetic control of gene delivery in vivo

US 10286073	Zhu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Haibao Zhu (Houston, Texas); Sheng Tong (Houston, Texas); Gang Bao (Houston, Texas)
ASSIGNEE(S)	ILISA TECH, INC. (Houston, Texas)
INVENTOR(S)	Haibao Zhu (Houston, Texas); Sheng Tong (Houston, Texas); Gang Bao (Houston, Texas)
ABSTRACT	This disclosure describes a composition and method of magnetic nanoparticles (MNP) that are bound to a baculovirus (BV). The MNP-BV can be systemically administered to a patient, and a strong magnetic field applied to the target tissue, thus allowing uptake and expression only in the target tissue. Off-target effects are not seen because the MNP-BC is inactivated by the complement system outside of the magnetic field.
FILED	Thursday, February 23, 2017
APPL NO	15/441089
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 9/5094 (20130101) A61K 41/00 (20130101) Original (OR) Class A61K 47/6923 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/87 (20130101) C12N 15/113 (20130101) C12N 2310/20 (20170501) C12N 2320/32 (20130101) C12N 2330/51 (20130101) C12N 2710/14043 (20130101)
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10286084 — Compositions for the inactivation of virus replication and methods of making and using the same

US 10286084	Cullen et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	DUKE UNIVERSITY (Durham, North Carolina); EMORY UNIVERSITY (Atlanta, Georgia)
ASSIGNEE(S)	Duke University (Durham, North Carolina); Emory University (Atlanta, Georgia); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Bryan R. Cullen (Durham, North Carolina); E. Matthew Kennedy (Durham, North Carolina); Hal P. Bogerd (Durham, North Carolina); Anand Kornepati (Durham, North Carolina); Adam Mefferd (Durham, North Carolina); Raymond F. Schinazi (Atlanta, Georgia)
ABSTRACT	Provided herein are recombinant constructs, vectors and expression cassettes including a first promoter which is suitably a tRNA promoter operably connected to a first polynucleotide encoding a first single guide RNA and a second promoter operably connected to a second polynucleotide encoding a Cas9 polypeptide. The first single guide RNA includes a first portion complementary to a strand of a target sequence of a DNA virus and a second portion capable of interacting with the Cas9 polypeptide. Also provided are codon optimized Staphylococcus aureus derived Cas9 polynucleotides and polypeptides with nuclear localization signals and optionally an epitope tag. Also provided are constructs for production of sgRNAs including a tRNA. Methods of inhibiting viral replication, inhibiting expression of a target sequence from a virus or treating a viral infection or viral induced cancer using the compositions are also provided.
FILED	Wednesday, February 18, 2015
APPL NO	15/119867
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 15/1131 (20130101) C12N 15/1132 (20130101) C12N 15/1133 (20130101) C12N 2310/20 (20170501) C12N 2740/15043 (20130101) C12N 2750/14143 (20130101)
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10286103 — Method and apparatus to control the heterogeneous flow of bone cement and improve osseointegration of cemented implant

US 10286103	Khandaker et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	University of Central Oklahoma (Edmond, Oklahoma)
ASSIGNEE(S)	University of Central Oklahoma (Edmond, Oklahoma)
INVENTOR(S)	Morshed Khandaker (Edmond, Oklahoma); Shahram Riahinezhad (Fort Lee, New Jersey)
ABSTRACT	The present invention provides processes for combined applications of making grooves on an implant surface, applying MgO nanoparticles with PMMA cement, restricting the cement movement by PCL nanofiber and tethering biomolecules with PCL nanofiber to enhance mechanical stability and osseointegration of PMMA cement with bone. This is achieved through enhanced osteoconductive properties, roughness, and less viable fracture originating sites at the bone-cement interface. Such combined applications of nanoparticle and nanofiber on the mechanical stability and osseointegration of cemented implant is heretofore unknown, but as provided by the present invention can solve the debonding problem of cemented implant from bone.
FILED	Thursday, May 10, 2018
APPL NO	15/976615
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/866 (20130101) A61B 2017/564 (20130101) A61B 2017/8655 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2846 (20130101) A61F 2/3601 (20130101) A61F 2/30723 (20130101) A61F 2/30734 (20130101) A61F 2/30907 (20130101) A61F 2002/30736 (20130101) A61F 2002/30919 (20130101) A61F 2310/00011 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/1841 (20130101) A61K 38/1875 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/02 (20130101) A61L 24/06 (20130101) A61L 24/06 (20130101) A61L 24/0015 (20130101) A61L 24/0089 (20130101) A61L 24/0089 (20130101) A61L 24/0094 (20130101) A61L 24/0094 (20130101) A61L 24/0094 (20130101) A61L 24/102 (20130101) Original (OR) Class A61L 24/108 (20130101) A61L 2300/102 (20130101) A61L 2300/252 (20130101) A61L 2300/404 (20130101) A61L 2300/414 (20130101) A61L 2400/12 (20130101) A61L 2430/02 (20130101) Compositions of Macromolecular Compounds C08L 33/12 (20130101) C08L 33/12 (20130101) C08L 33/12 (20130101) C08L 67/04 (20130101)
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10286116 — Methods and materials for reducing venous neointimal hyperplasia of an arteriovenous fistula or graft

US 10286116	Misra et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S)	Sanjay Misra (Rochester, Minnesota); Allan B. Dietz (Chatfield, Minnesota)
ABSTRACT	This document provides methods and materials involved in reducing venous neointimal hyperplasia (VNH) of an arteriovenous fistula (AVF) or graft. For example, methods and materials for using stem cells (e.g., mesenchymal stem cells), extracellular matrix material, or a combination of stem cells and extracellular matrix material to reduce VNH of AVFs or grafts are provided.
FILED	Tuesday, April 12, 2016
APPL NO	15/097070
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/28 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/507 (20130101) A61L 27/3633 (20130101) A61L 27/3834 (20130101) A61L 31/005 (20130101) Original (OR) Class
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10287257 — Linker molecule for multiplex recognition by atomic force microscopy (AFM)

US 10287257	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Peiming Zhang (Gilbert, Arizona); Stuart Lindsay (Phoenix, Arizona); Saikat Manna (Tempe, Arizona); Subhadip Senapati (Tempe, Arizona)
ABSTRACT	Some of the embodiments of the present disclosure relate to a compound of the formula, and methods of preparing and using same.
FILED	Thursday, May 07, 2015
APPL NO	15/308517
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 247/04 (20130101) Heterocyclic Compounds C07D 249/04 (20130101) C07D 249/06 (20130101) Original (OR) Class C07D 487/04 (20130101) C07D 491/052 (20130101) Peptides C07K 14/001 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2310/3517 (20130101)
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10287262 — Eicosanoid derivatives

US 10287262	Schunck et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Max-Delbrueck-Centrum fuer Molekulare Medizin (Berlin, Germany); Board of Regents of University of Texas System (Austin, Texas)
ASSIGNEE(S)	MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN (Berlin, Germany); BOARD OF REGENTS OF UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Wolf-Hagen Schunck (Berlin, Germany); Gerd Wallukat (Berlin, Germany); Robert Fischer (Berlin, Germany); Cosima Arnold (Ulm, Germany); Dominik N. Mueller (Berlin, Germany); Narender Puli (Dallas, Texas); John R. Falck (Dallas, Texas)
ABSTRACT	The present invention provides compounds (n-3 PUFA derivatives) of formula (I): that modulate conditions associated with cardiac damage, especially cardiac arrhythmias.
FILED	Wednesday, January 27, 2016
APPL NO	15/007354
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 233/09 (20130101) C07C 233/47 (20130101) C07C 233/49 (20130101) C07C 235/28 (20130101) C07C 235/76 (20130101) C07C 275/14 (20130101) C07C 275/16 (20130101) C07C 275/20 (20130101) Heterocyclic Compounds C07D 303/38 (20130101) Original (OR) Class
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10287274 — 5-hydroxytryptamine receptor 7 activity modulators and their method of use

US 10287274	Canney et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania)
ASSIGNEE(S)	TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania)
INVENTOR(S)	Daniel J. Canney (Ambler, Pennsylvania); Benjamin E. Blass (Eagleville, Pennsylvania); Rong Gao (Eugene, Oregon); Magid Abou-Gharbia (Exton, Pennsylvania)
ABSTRACT	Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
FILED	Wednesday, September 27, 2017
APPL NO	15/716773
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 307/33 (20130101) C07D 307/94 (20130101) C07D 405/06 (20130101) C07D 405/12 (20130101) Original (OR) Class
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10287279 — Inhibitors of human 12/15-lipoxygenase

US 10287279	Van Leyen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	THE CHILDREN'S HOSPITAL CORPORATION (Boston, Massachusetts); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Klaus Joachin Van Leyen (Medford, Massachusetts); Theodore R. Holman (Santa Cruz, California); David J. Maloney (Point of Rocks, Maryland); Ajit Jadhav (Chantilly, Virginia); Anton Simeonov (Santa Cruz, California); Ganesha Rai (Arlington, Virginia)
ABSTRACT	A systematic screening has revealed a family of compounds that exhibit inhibitory effects on 12/15-lipoxygenase. Accordingly, the present invention relates to the use of these compounds for the inhibition of 12/15-lipoxygenase and for the treatment of a condition involving 12/15-lipoxygenase. Exemplary conditions include, but are not limited to, stroke, periventricular leukomalacia, cardiac arrest with resuscitation, atherosclerosis, Parkinson's disease, Alzheimer's disease, and breast cancer.
FILED	Friday, February 19, 2016
APPL NO	15/048330
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/421 (20130101) A61K 31/422 (20130101) A61K 31/426 (20130101) A61K 31/4245 (20130101) A61K 31/4709 (20130101) A61K 31/4725 (20130101) Heterocyclic Compounds C07D 213/85 (20130101) C07D 239/42 (20130101) C07D 263/48 (20130101) C07D 277/42 (20130101) C07D 277/56 (20130101) C07D 413/04 (20130101) Original (OR) Class
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10287282 — Methods and agents for treating disease

US 10287282	Panicker et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	ANGION BIOMEDICA CORP. (Uniondale, New York)
ASSIGNEE(S)	ANGION BIOMEDICA CORP. (Uniondale, New York)
INVENTOR(S)	Bijoy Panicker (Holtsville, New York); Lambertus J. W. M. Oehlen (Westbury, New York)
ABSTRACT	The present invention provides compounds having the general structural formula (I) [formula should be inserted here] and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving elevated levels of aldosterone or abnormal or excessive fibrosis, such as kidney disease and hypertension.
FILED	Tuesday, December 29, 2015
APPL NO	15/540592
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/427 (20130101) A61K 31/4439 (20130101) Heterocyclic Compounds C07D 417/06 (20130101) Original (OR) Class C07D 417/14 (20130101)
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10287283 — Read-through compound prodrugs suppressing premature nonsense mutations

US 10287283	Bertoni et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Carmen Bertoni (Los Angeles, California); Jasbir Singh (Naperville, Illinois)
ABSTRACT	Premature termination codon readthrough prodrug compounds, compositions thereof, and methods of making and using the same are provided. In certain embodiments, the compounds are of Formula Ia or a pharmaceutically acceptable salt, solvate, polymorph, hydrate, ester, isomer, stereoisomer, or tautomer thereof, wherein R, A and W are as described herein.
FILED	Monday, September 17, 2018
APPL NO	16/133230
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 417/06 (20130101) Original (OR) Class C07D 417/14 (20130101)
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10287297 — Epoxyazulene derivatives useful for treating cancer and diabetes

US 10287297	Beutler et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Heatlh and Human Services (Washington, District of Columbia); Fundació Institut Català d'Investigació Química (ICIQ) (Tarragona, Spain); Universitat Rovira i Virgili (Tarragona, Spain)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Fundació Institut Català d'Investigació Quimica (ICIQ) (Tarragona, Spain); Universitat Rovira i Virgili (Tarragona, Spain)
INVENTOR(S)	John A. Beutler (Union Bridge, Maryland); Antonio M. Echavarren (Tarragona, Spain); Laura Lopez (Barcelona, Spain); Fernando Bravo (Valls, Spain); Lorena Riesgo (El Bérrón, Spain); Tanya Tannaquil Ransom (Germantown, Maryland)
ABSTRACT	Disclosed is a compound of formula (I) in which R¹-R⁵and X¹are as described herein. Also provided are methods of using a compound of formula (I), including a method of treating cancer and a method of treating diabetes.
FILED	Wednesday, April 13, 2016
APPL NO	15/564353
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 35/02 (20180101) Heterocyclic Compounds C07D 487/08 (20130101) C07D 493/08 (20130101) Original (OR) Class C07D 495/08 (20130101)
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10287312 — Cyclic peroxides as prodrugs for selective delivery of agents

US 10287312	Renslo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Adam R. Renslo (Oakland, California); Erica M. W. Lauterwasser (Wachenheim, Germany); Shaun D. Fontaine (Walnut Creek, California); Benjamin B. Spangler (San Francisco, California); James A. Wells (Burlingame, California)
ABSTRACT	Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5]decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
FILED	Friday, February 13, 2015
APPL NO	15/118268
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/357 (20130101) A61K 31/404 (20130101) A61K 31/427 (20130101) A61K 31/435 (20130101) A61K 31/437 (20130101) A61K 31/444 (20130101) A61K 31/496 (20130101) A61K 31/513 (20130101) A61K 31/662 (20130101) A61K 31/4025 (20130101) A61K 31/4192 (20130101) A61K 31/4709 (20130101) A61K 31/4745 (20130101) A61K 31/4985 (20130101) A61K 31/7072 (20130101) A61K 31/7076 (20130101) A61K 31/7135 (20130101) A61K 47/64 (20170801) A61K 47/6803 (20170801) A61K 51/0459 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Heterocyclic Compounds C07D 323/02 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 407/12 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) C07D 471/14 (20130101) C07D 487/04 (20130101) C07D 491/107 (20130101) C07D 491/113 (20130101) C07D 491/153 (20130101) C07D 493/04 (20130101) C07D 493/14 (20130101) C07D 519/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1804 (20130101) C07F 9/65517 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/06 (20130101) C07H 19/16 (20130101) Original (OR) Class C07H 19/167 (20130101) Peptides C07K 7/06 (20130101) Technologies for Adaptation to Climate Change Y02A 50/411 (20180101)
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10287313 — RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays

US 10287313	Damha et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (Montreal, Canada); WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); Saima Akhtar (Niskayuna, New York)
ASSIGNEE(S)	The Royal Institution for the Advancement of Learning/McGill University (Montreal, Canada); Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Masad Damha (St-Hubert, Canada); Jeremy Lackey (Montreal, Canada); Debbie Mitra (Ottawa, Canada); Marvin Wickens (Madison, Wisconsin); Franco Cerrina (Madison, Wisconsin); Mark Somoza (Weidling, Austria)
ABSTRACT	The present invention is directed to RNA monomers comprising O-acetal levulinyl protecting groups at the 2′ and/or the 5′-hydroxy functionalities of the ribose moiety. Said monomers may be incorporated into oligoribonucleotides or RNA polynucleotides. Furthermore, the invention is directed to methods for the synthesis of said RNA monomers, oligoribonucleotides and RNA polynucleotides, as well as methods for their deprotection and methods for the use of said compounds and compositions comprising said compounds. In particular, such compounds and compositions comprising them are used in methods for light-directed synthesis of RNA microarrays.
FILED	Tuesday, December 29, 2015
APPL NO	14/983504
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/067 (20130101) C07H 19/167 (20130101) C07H 21/02 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6837 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/55 (20151101)
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10287337 — Compositions and methods for treating acute and chronic pain by local antagonism of CGRP receptors, or combination with sodium channel inhibition or with anti-inflammatory agents

US 10287337	Xie et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	AfaSci, Inc. (Redwood City, California)
ASSIGNEE(S)	AFASCI, Inc. (Redwood City, California)
INVENTOR(S)	Xinmin Xie (Burlingame, California); Conrado Pascual (Santa Clara, California); Xi Xie (Cambridge, Massachusetts); James Xie (Brookline, Massachusetts)
ABSTRACT	The present invention provides compositions, and methods for local administration of certain peptides or combination with certain small molecules that produce analgesia and anti-inflammation in a mammal. Exemplary polypeptides provide peripheral analgesia and anti-inflammation when administered via local topical, subcutaneous, intradermal, or intranasal administration, to provide analgesia and anti-inflammation. Through antagonism of peripheral CGRP receptors alone, or in combination with inhibition of sensory sodium channels or anti-inflammation, the compositions of the invention provide local therapeutic pain relief with minimal undesired systemic side effects in a subject. Also provided are improved peptide delivery techniques including microneedle unit dose administering apparatus and methods. Also provided are hydrogel formulations for sustained local delivery to a subject of one or more of the compositions according to the invention in a therapeutically effective amount, thereby providing local pain relief and/or reducing associated inflammation.
FILED	Monday, June 01, 2015
APPL NO	14/727589
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) A61K 38/00 (20130101) A61K 38/10 (20130101) A61K 38/23 (20130101) A61K 45/06 (20130101) Peptides C07K 7/08 (20130101) C07K 14/723 (20130101) C07K 14/57527 (20130101) Original (OR) Class
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10287340 — Anti-HIV domain antibodies and method of making and using same

US 10287340	Dimitrov et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Dimiter S. Dimitrov (Frederick, Maryland); Weizao Chen (Frederick, Maryland)
ABSTRACT	The invention provides single domain antibodies and derivatives thereof that bind antigens of interest, which are stable, soluble, and do not tend to aggregate. The invention also provides methods for constructing a dAb library and methods for screening dAb libraries to identify the dAb of the invention. The invention also provide methods of treating or preventing conditions by antigen neutralization by administering the dAbs of the invention.
FILED	Monday, September 28, 2015
APPL NO	14/867793
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/1774 (20130101) A61K 39/42 (20130101) A61K 47/6841 (20170801) Peptides C07K 14/70514 (20130101) C07K 16/005 (20130101) C07K 16/1045 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 16/2812 (20130101) C07K 2317/21 (20130101) C07K 2317/32 (20130101) C07K 2317/53 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) C07K 2317/569 (20130101) C07K 2319/35 (20130101)
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10287347 — Treatment of cancer with anti-lap monoclonal antibodies

US 10287347	Weiner et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Howard L. Weiner (Brookline, Massachusetts); Galina Gabriely (Brookline, Massachusetts); Andre Pires Da Cunha (Boston, Massachusetts); Takatoku Oida (Osaka, Japan)
ABSTRACT	Described herein are compositions and methods relating to LAP-binding agents, including, for example, anti-LAP antibodies, and to their use in methods of treatment of cancer. LAP-binding agents affected both systemic and intra-tumor immunity and were shown effective to treat a broad spectrum of cancer types.
FILED	Thursday, July 13, 2017
APPL NO	15/649373
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/22 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 16/2839 (20130101) C07K 2317/24 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2317/626 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/495 (20130101)
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10287350 — Chimeric antigen receptors targeting CD-19

US 10287350	Kochenderfer
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	James N. Kochenderfer (Bethesda, Maryland)
ABSTRACT	The invention is directed to a chimeric antigen receptor (CAR) directed against CD19, which comprises an amino acid sequence of any one of SEQ ID NO: 1-SEQ ID NO: 13. The invention also provides T-cells expressing the CAR and methods for destroying malignant B-cells.
FILED	Monday, June 01, 2015
APPL NO	15/315533
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/705 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70535 (20130101) C07K 14/70578 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/3061 (20130101) C07K 2317/21 (20130101) C07K 2317/70 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101)
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10287355 — Methods and compositions for modulating lymphangiogenesis, E.G., to treat transplant rejection, in a subject

US 10287355	Chen
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Lu Chen (Berkeley, California)
ABSTRACT	Methods of modulating the occurrence of lymphangiogenesis in a subject are provided. In some instances, the method is a method of treating transplant rejection in the subject. Aspects of the methods include administering to the subject an effective amount of: a first antagonist for a tyrosine kinase receptor and a second antagonist for an integrin receptor. In some embodiments, the methods include enhancing survival of transplanted tissue in a subject. Aspects of the invention further include compositions, e.g., pharmaceutical compositions and kits that find use in methods of the invention.
FILED	Monday, June 13, 2016
APPL NO	15/181268
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/2842 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 2317/76 (20130101)
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10287365 — Anti-GD2 antibodies

US 10287365	Cheung et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Memorial Sloan Kettering Cancer Center (New York, New York)
ASSIGNEE(S)	Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S)	Nai-Kong Cheung (New York, New York); Mahiuddin Ahmed (Verona, New Jersey); Hong Xu (New York, New York)
ABSTRACT	In this application are described chimeric, humanized, affinity matured, stability enhanced, and bispecific Anti-GD2 antibodies and fragments thereof. Also provided are methods of using individual antibodies or compositions thereof for the detection, prevention, and/or therapeutical treatment of GD2-related diseases, in particular, neuroblastoma.
FILED	Friday, May 19, 2017
APPL NO	15/600657
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/44 (20130101) C07K 16/46 (20130101) C07K 16/461 (20130101) C07K 16/468 (20130101) Original (OR) Class C07K 16/2803 (20130101) C07K 16/3084 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/33 (20130101) C07K 2317/72 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/567 (20130101) C07K 2317/732 (20130101) C07K 2317/734 (20130101)
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10287401 — Cationic mucic acid polymer-based delivery systems

US 10287401	Davis et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Mark E. Davis (Pasadena, California); Dorothy Pan (Pasadena, California)
ABSTRACT	The present disclosure is directed to polymer and polymer conjugate-based nanoparticle delivery systems for delivering biological agents, and methods of making and using these compositions. Certain embodiments of the present disclosure provide polymers comprising alternating charged and uncharged segments comprising one or more of the following structural units of Formula (I) or Formula (II) or Formula (III): wherein is an uncharged segment comprising polyalkylene glycol; and B is a cationically charged segment comprising at least one polyhydroxy linkage.
FILED	Monday, June 13, 2016
APPL NO	15/180201
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) A61K 47/34 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/40 (20130101) C08G 73/028 (20130101) C08G 79/08 (20130101) C08G 81/00 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/12 (20130101)
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10287546 — Kits for neural conversion of human embryonic stem cells

US 10287546	Chambers et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S)	Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S)	Stuart Chambers (San Francisco, California); Lorenz Studer (New York, New York)
ABSTRACT	The present invention relates generally to the field of cell biology of stem cells, more specifically the directed differentiation of pluripotent or multipotent stem cells, including human embryonic stem cells (hESC), somatic stem cells, and induced human pluripotent stem cells (hiPSC) using novel culture conditions. Specifically, methods are provided for obtaining neural tissue, floor plate cells, and placode including induction of neural plate development in hESCs for obtaining midbrain dopamine (DA) neurons, motorneurons, and sensory neurons. Further, neural plate tissue obtained using methods of the present inventions are contemplated for use in co-cultures with other tissues as inducers for shifting differentiation pathways, i.e. patterning.
FILED	Friday, January 31, 2014
APPL NO	14/169286
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 2501/41 (20130101) C12N 2501/60 (20130101) C12N 2501/415 (20130101) C12N 2506/02 (20130101)
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10287552 — Generation of hepatocytes from pluripotent stem cells

US 10287552	Gupta et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York)
ASSIGNEE(S)	Albert Einstein College of Medicine (Bronx, New York)
INVENTOR(S)	Sanjeev Gupta (Scarsdale, New York); Sriram Bandi (Belleville, New Jersey)
ABSTRACT	Methods are provided for producing differentiated cells from stem cells, including producing hepatocytes. Compositions thereof are also provided, as are methods of treating a liver disorder.
FILED	Wednesday, February 21, 2018
APPL NO	15/900834
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/407 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) Original (OR) Class C12N 5/0672 (20130101) C12N 2500/84 (20130101) C12N 2501/999 (20130101) C12N 2502/14 (20130101) C12N 2506/02 (20130101)
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10287578 — DNAzyme-nanoparticle conjugates and methods of use thereof

US 10287578	Carter et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	THE UNIVERSITY OF NOTRE DAME (Notre Dame, Indiana)
ASSIGNEE(S)	The University of Notre Dame (Notre Dame, Indiana)
INVENTOR(S)	James Carter (Mishawaka, Indiana); Malcolm J. Fraser, Jr. (Granger, Indiana)
ABSTRACT	The present invention relates to DNAzymes (also known as deoxyribozymes, DNA enzymes, catalytic DNA, or DZ), which are conjugated to nanoparticles (NP) to facilitate the detection of nucleic acids. One aspect of the invention relates to compounds comprising DNAzymes conjugated to nanoparticles (DZ-NP), such as metallic or gold nanoparticles, and methods for their synthesis. Another aspect of the invention relates to methods of using the conjugated compounds to detect nucleic acids, such as genomic material or transcripts of infectious agents, such as viruses, exemplified by applications demonstrating visual detection of Flavivirus RNA molecules, such as dengue virus, or Alphavirus RNA molecules, such as chikungunya virus, in short time periods, using compositions comprising stable components.
FILED	Monday, June 16, 2014
APPL NO	14/757293
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 15/1131 (20130101) C12N 2310/127 (20130101) C12N 2310/351 (20130101) C12N 2310/3517 (20130101) C12N 2320/10 (20130101) C12N 2770/24122 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 2521/345 (20130101) C12Q 2565/113 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/588 (20130101) G01N 33/5308 (20130101) G01N 33/56983 (20130101) G01N 2333/181 (20130101) G01N 2333/185 (20130101) Technologies for Adaptation to Climate Change Y02A 50/51 (20180101) Y02A 50/53 (20180101) Y02A 50/60 (20180101)
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10287584 — Compounds and methods for the modulation of COMP

US 10287584	Guo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	Ionis Pharmaceuticals, Inc. (Carlsbad, California); Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S)	IONIS PHARMACEUTICALS, INC. (Carlsbad, California); THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Shuling Guo (Carlsbad, California); Punit P. Seth (Carlsbad, California); Jacqueline T. Hecht (Houston, Texas); Karen LaShea Posey (Houston, Texas)
ABSTRACT	In certain embodiments, hybridization results in modulation of the amount activity or expression of the target nucleic acid in a cell. In certain embodiments, the target nucleic acid is a nucleic acid that encodes cartilage oligomeric matrix protein. In certain embodiments, the target nucleic acid is a nucleic acid expressed in the growth plate, tendon, or cartilage.
FILED	Thursday, November 12, 2015
APPL NO	15/526447
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 31/232 (20130101) A61K 31/235 (20130101) A61K 31/235 (20130101) A61K 31/405 (20130101) A61K 31/405 (20130101) A61K 31/713 (20130101) A61K 31/7076 (20130101) A61K 31/7125 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/00 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/321 (20130101) C12N 2310/341 (20130101) C12N 2320/31 (20130101)
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10287587 — Prostate cancer-specific alterations in ERG gene expression and detection and treatment methods based on those alterations

US 10287587	Srivastava et al.
FUNDED BY	Department of Defense (DOD) Uniformed Services University of the Health Sciences (USUHS) Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland)
ASSIGNEE(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
INVENTOR(S)	Shiv Srivastava (Potomac, Maryland); Albert Dobi (Rockville, Maryland); Taduru Sreenath (Germantown, Maryland); Gyorgy Petrovics (Bethesda, Maryland); Chen Sun (Bethesda, Maryland)
ABSTRACT	The disclosure describes alterations in ERG gene expression. ERG isoforms and promoter sequence of the ERG gene that are involved in, or associated with, prostate cancer are provided. The disclosure further provides therapeutic compositions and methods of detecting, diagnosing, prognosing, and treating prostate cancer, including biomarkers for detecting the expression of two or more of the following genes: PSA/KLK3, PMEPA1, NKX3.1, ODC1, AMD1, and ERG.
FILED	Thursday, August 22, 2013
APPL NO	13/974007
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2320/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101)
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10287588 — Compositions and methods to treating hemoglobinopathies

US 10287588	Milsom et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
ASSIGNEE(S)	THE CHILDRENS'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S)	Michael Milsom (Dossenheim, Germany); David A. Williams (Dover, Massachusetts); Richard Gregory (Brookline, Massachusetts)
ABSTRACT	Embodiment herein provide specially designed synthetic BCL11A-targeting microRNAs for RNA polymerase II expression, and methods of use to treat hemoglobinopathies such as sickle cell disease or thalassemia by increasing the expression levels of fetal hemoglobin levels. In particular illustrative embodiment, the present invention provides, in part, improved compositions and methods for achieving gene therapy in hematopoietic cells and hematopoietic precursor cells, including erythrocytes, erythroid progenitors, and embryonic stem cells. The invention further provides improved gene therapy methods for treating hematopoietic-related disorders.
FILED	Friday, April 24, 2015
APPL NO	15/306527
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/113 (20130101) C12N 15/1135 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) C12N 2740/10032 (20130101) C12N 2740/10043 (20130101)
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10287617 — Methods for in vitro—in vivo efficacy determination

US 10287617	Knudson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado)
ASSIGNEE(S)	Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S)	Susan E. Knudson (Fort Collins, Colorado); Richard A. Slayden (Fort Collins, Colorado)
ABSTRACT	The invention provides methods for determining and evaluating the in vitro-in vivo activity relationship of the efficacy of families of compounds for infectious diseases such as tuberculosis. The validity of the methods can be confirmed by evaluation of the compounds in animal models, for example, in murine models of tuberculosis. Examples of families of antibacterial compounds that can be evaluated for in vivo efficacy using the in vitro methods described herein include benzimidazoles, pyridopyrazines, pteridines, diphenyl ethers, beta-lactams, PBP inhibitors, and compounds that are non-ribonucleic acid and protein synthesis inhibitors. The methods can be used to evaluate classes of small molecule compounds and inhibitors that may be effective against any bacterial pathogen. The methods aid the identification of compounds, such as various benzimidazoles, with modes of action having activity against clinical isolates, as well as non-replicating persistent bacilli, which can therefore enhance current clinical therapeutic regimens.
FILED	Wednesday, March 11, 2015
APPL NO	15/124651
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Original (OR) Class
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10287628 — Methods and kits for identifying polypeptide binding sites in a genome

US 10287628	Zeitlinger et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) NIH Office of the Director (NIHOD)
APPLICANT(S)	STOWERS INSTITUTE FOR MEDICAL RESEARCH (Kansas city, Missouri)
ASSIGNEE(S)	Stowers Institute for Medical Research (Kansas City, Missouri)
INVENTOR(S)	Julia Zeitlinger (Kansas City, Missouri); Qiye He (Shanghai, China PRC); Jeffrey Johnston (Kansas City, Missouri)
ABSTRACT	The present invention provides, inter alia, methods and kits for identifying where a polypeptide of interest binds in a genome. The methods include a) carrying out a chromatin immunoprecipitation coupled to exonuclease digestion (ChIP-exo) process with an antibody against the polypeptide of interest; (b) extracting a polynucleotide fragment to which the polypeptide of interest binds; (c) carrying out a library preparation protocol adapted from an individual nucleotide resolution UV cross-linking and immunoprecipitation (iCLIP) process on the ChIP-exo processed polynucleotide fragment; and (d) sequencing the resulting polynucleotides. The kits include: (a) reagents sufficient to carry out ChIP-exo; (b) reagents sufficient to carry out the library preparation protocol adapted from the iCLIP process; and (c) instructions for use.
FILED	Friday, December 18, 2015
APPL NO	15/536107
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2537/159 (20130101) C12Q 2537/159 (20130101) C12Q 2537/159 (20130101) C12Q 2537/159 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101)
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10287630 — Single cell nucleic acid detection and analysis

US 10287630	Xie et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Xiaoliang Sunney Xie (Lexington, Massachusetts); Katsuyuki Shiroguchi (Arlington, Massachusetts); Peter A. Sims (Cambridge, Massachusetts); Tony Z. Jia (Cambridge, Massachusetts)
ABSTRACT	Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
FILED	Wednesday, October 11, 2017
APPL NO	15/730157
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/131 (20130101) C12Q 2525/301 (20130101) C12Q 2537/16 (20130101) C12Q 2563/179 (20130101)
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10287631 — Methods of lowering the error rate of massively parallel DNA sequencing using duplex consensus sequencing

US 10287631	Salk et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute on Aging (NIA)
APPLICANT(S)	UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
ASSIGNEE(S)	UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
INVENTOR(S)	Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington)
ABSTRACT	Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
FILED	Wednesday, July 26, 2017
APPL NO	15/660785
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101)
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10287699 — Sensors and methods of manufacture thereof

US 10287699	Madangopal et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Rajtarun Madangopal (West Lafayette, Indiana); Jenna L. Rickus (West Lafayette, Indiana)
ABSTRACT	The invention generally relates to sensors, methods of manufacture thereof, methods of use thereof for sensing analytes, such as small molecules and biomolecules, and methods of immobilization. In certain embodiments, the invention provides a multi-analyte sensor. The multi-analyte sensor includes a plurality of sensing electrodes. Each sensing electrode is functionalized with a different molecule (e.g., biomolecule), at least two of the sensing electrodes are spaced apart prior to and after functionalization by 100 μm or less, and there is no cross-talk between the plurality of sensing electrodes.
FILED	Wednesday, April 16, 2014
APPL NO	14/254475
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/24 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/567 (20130101) C25D 5/48 (20130101) C25D 7/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3271 (20130101) G01N 27/3276 (20130101)
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10288532 — Methods, apparatuses and systems for collection of tissue sections

US 10288532	Hayworth et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Kenneth Jeffrey Hayworth (Ashburn, Virginia); Richard Schalek (Wakefield, Massachusetts); Juan Carlos Tapia (Bronx, New York); Narayanan Kasthuri (Cambridge, Massachusetts); Jeff Lichtman (Cambridge, Massachusetts)
ABSTRACT	Methods, apparatuses and systems for facilitating automated or semi-automated collection of tissue samples cut by a microtome. In one example, a collection apparatus may be moved back and forth between respective positions at which the collection apparatus is operatively coupled to a microtome so as to collect cut tissue samples, or routine access to the microtome is provided. Relatively easy movement and positioning of the collection apparatus is facilitated, while at the same time ensuring structural stability and appropriate alignment and/or isolation between the collection apparatus and the microtome. A fluid reservoir receives samples cut by the microtome, and the collection apparatus may collect samples via a conveyor-like substrate disposed near/in the reservoir. A linear movement of the substrate may be controlled based on a cutting rate of the microtome, and the fluid level in the reservoir may be automatically maintained to facilitate effective sample collection.
FILED	Monday, August 07, 2017
APPL NO	15/670784
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 16/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/06 (20130101) Original (OR) Class G01N 35/00009 (20130101) G01N 2001/061 (20130101) G01N 2001/065 (20130101) G01N 2001/066 (20130101) G01N 2001/068 (20130101)
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10288567 — Time-resolved laser-induced fluorescence spectroscopy systems and uses thereof

US 10288567	Butte et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Cedars-Sinai Medical Center (Los Angeles, California)
ASSIGNEE(S)	Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S)	Pramod Butte (Los Angeles, California); Paul Lapchak (San Diego, California); David Scott Kittle (Colton, California)
ABSTRACT	The invention provides systems for characterizing a biological sample by analyzing emission of fluorescent light from the biological sample upon excitation and methods for using the same. The system includes a laser source, collection fibers, a demultiplexer and an optical delay device. All references cited herein are incorporated by reference in their entirety as though fully set forth. Unless defined otherwise, technical and scientific tens used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
FILED	Wednesday, June 29, 2016
APPL NO	15/196354
ART UNIT	2884 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/0084 (20130101) A61B 5/1459 (20130101) A61B 5/4866 (20130101) A61B 5/14556 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0218 (20130101) G01J 3/2889 (20130101) G01J 3/4406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) G01N 21/645 (20130101) G01N 21/6402 (20130101) G01N 21/6408 (20130101) G01N 21/6428 (20130101) G01N 21/6486 (20130101) Original (OR) Class G01N 2021/6417 (20130101) G01N 2021/6421 (20130101) G01N 2021/6484 (20130101) G01N 2201/06113 (20130101)
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10288568 — Raman probe and methods of imaging

US 10288568	Zavaleta
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)
INVENTOR(S)	Cristina Zavaleta (Los Angeles, California)
ABSTRACT	The present disclosure provides for a Raman probes and methods of imaging including a Raman probe. The Raman probes include a Raman detection system configured to illuminate an area of a subject or a sample with a light source and to receive Raman scattered light energy from the area. The Raman probe can include a proximity sensor system and a fluorescent imaging system. A method of imaging introduces a Raman probe to a subject. Fluorescent light is detected from an area of the subject, which guides the Raman probe to the area. The Raman probe is positioned at a target distance from the area using the proximity sensor system, and by exposing the area to a light beam from the Raman detection system. The light beam, Raman scattered light energy, is scattered by a Raman agent associated with the area. Raman scattered light is detected using the Raman imaging device.
FILED	Friday, December 08, 2017
APPL NO	15/835608
ART UNIT	2886 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/07 (20130101) A61B 5/00 (20130101) A61B 5/0075 (20130101) A61B 5/0084 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/02 (20130101) G01J 3/44 (20130101) G01J 3/0221 (20130101) G01J 3/4406 (20130101) G01J 3/4412 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 21/658 (20130101) Original (OR) Class G01N 21/6456 (20130101) G01N 2021/6439 (20130101)
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10288599 — Systems and devices for molecule sensing and method of manufacturing thereof

US 10288599	Gyarfas et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	ARIZONA BOARD OF REGENTS on behalf of ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Brett Gyarfas (Chandler, Arizona); Stuart Lindsay (Phoenix, Arizona); Pei Pang (Tempe, Arizona)
ABSTRACT	Embodiments of the disclosure are directed to a device for molecule sensing. In some embodiments, the device includes a first electrode separated from a second electrode by a dielectric layer. The first electrode comprises a large area electrode and the second electrode comprises a small area electrode. At least one opening (e.g., trench) cut or otherwise created into the dielectric layer exposes a tunnel junction therebetween whereby target molecules in solution can bind across the tunnel junction.
FILED	Thursday, January 21, 2016
APPL NO	15/002828
ART UNIT	1677 — Printing/Measuring and Testing
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44791 (20130101) G01N 33/48721 (20130101) Original (OR) Class Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/20 (20130101)
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10288608 — Polynucleotide conjugates and methods for analyte detection

US 10288608	Kozlov et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Prognosys Biosciences, Inc. (San Diego, California)
ASSIGNEE(S)	Prognosys Biosciences, Inc. (San Diego, California)
INVENTOR(S)	Igor A. Kozlov (San Diego, California); John Andrew Altin (San Diego, California); Petr Capek (San Diego, California); Mark S. Chee (San Diego, California)
ABSTRACT	The present disclosure provides polynucleotide conjugates, methods, and assay systems for use in detecting the presence, absence, and/or amount of an analyte in a sample. Various polynucleotide conjugates, conjugate pairs, sets, libraries, and assay systems comprising the same are disclosed. In particular, methods and assay systems for antibody detection and analysis are provided. For example, assays capable of high levels of multiplexing are used for antibody detection and analysis in a biological sample, e.g., Lyme disease patient samples. The presently disclosed polynucleotide conjugates, methods, and assay systems can be used to provide sensitive and reliable diagnosis, even at early stages of a disease or condition. Use for monitoring disease progression and prognosis is also disclosed.
FILED	Friday, November 07, 2014
APPL NO	15/035206
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6804 (20130101) C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 2563/131 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/6845 (20130101) G01N 33/6854 (20130101) G01N 33/54306 (20130101) G01N 33/54393 (20130101) Original (OR) Class G01N 2458/10 (20130101)
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10288610 — Vitro assays for detecting Salmonella enterica serotype typhi

US 10288610	Charles et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts); International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B) (Dacca, Bangladesh); The Chancellor, Masters and Scholars of the University of Oxford (Oxford, United Kingdom)
ASSIGNEE(S)	THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH, BANGLADESH (ICDDR,B) (Dacca, Bangladesh); THE CHANGELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (Oxford, United Kingdom)
INVENTOR(S)	Richelle Charles (Cambridge, Massachusetts); Edward T. Ryan (Wellesley, Massachusetts); Firdausi Qadri (Dacca, Bangladesh); Stephen Baker (Ho Chi Minh, Viet Nam)
ABSTRACT	Provided are assays, kits and compositions for testing subjects, particularly asymptomatic subjects, to ascertain whether or not they are carriers of Salmonella enterica serotype Typhi. Methods for detecting the presence of Salmonella enterica serotype Typhi indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided.
FILED	Tuesday, November 12, 2013
APPL NO	14/441642
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/0275 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54313 (20130101) G01N 33/56916 (20130101) Original (OR) Class G01N 2333/255 (20130101) G01N 2469/20 (20130101)
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10288611 — Lateral flow device for diagnosing microbial infections

US 10288611	Marr et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Kieren A. Marr (Baltimore, Maryland); Janet F. Staab (Baltimore, Maryland); Marta Feldmesser (New York, New York)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland); Albert Einstein College of Medicine, Inc. (Bronx, New York)
INVENTOR(S)	Kieren A. Marr (Baltimore, Maryland); Janet F. Staab (Baltimore, Maryland); Marta Feldmesser (New York, New York)
ABSTRACT	Fungal infections are difficult to diagnose. The most common filamentous fungal infection, aspergillosis, carries with it a high mortality. Culture of the organism is difficult and obtaining samples, e.g., though a lung biopsy, sometimes causes morbidity. Biomarkers that indicate ‘early’ infection in it development are sought after. One such biomarker is detection of galactomannan (GM), a polysaccharide that is attached to hyphal cell walls and secreted during growth of the organism. Galactomannan is excreted in urine. Disclosed herein is a lateral flow assay comprising monoclonal antibodies that recognize specific residues of Aspergillus fumigates for detecting GM in urine samples to provide a point-of-care detection device to allow for frequent screening and early diagnosis in patients at high risk for infection.
FILED	Tuesday, November 23, 2010
APPL NO	13/511264
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 16/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/66 (20130101) G01N 33/569 (20130101) G01N 33/54366 (20130101) G01N 33/56961 (20130101) Original (OR) Class G01N 2400/02 (20130101) G01N 2469/10 (20130101)
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10288612 — Methods for diagnosing and treating eosinophilic esophagitis

US 10288612	Fulkerson
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Children's Hospital Medical Center (Cincinnati, Ohio)
ASSIGNEE(S)	Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S)	Patricia C. Fulkerson (Cincinnati, Ohio)
ABSTRACT	Disclosed are methods of diagnosing and treating a subject with active or inactive eosinophilic esophagitis (EoE). The methods may include the steps of detecting whether a level of eosinophil lineage-committed progenitor (EoP) is elevated in a blood sample obtained from a subject, diagnosing the subject with active EoE when an EoP level in the sample is elevated above a pre-determined cut-off value and diagnosing the subject with inactive EoE when the EoP level in the sample is below a pre-determined cut-off value; and treating the subject diagnosed with active EoE. Kits related to same are also disclosed.
FILED	Tuesday, November 22, 2016
APPL NO	15/358864
ART UNIT	1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/20 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/56972 (20130101) Original (OR) Class G01N 2800/06 (20130101) G01N 2800/24 (20130101)
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10288619 — Biomarkers for human monocyte myeloid-derived suppresor cells

US 10288619	Cooper et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Kevin D. Cooper (Cleveland, Ohio); Thomas S. McCormick (Cleveland, Ohio); David S. Soler (Cleveland, Ohio); Andrew Young (Cleveland, Ohio)
ABSTRACT	A method for diagnosing an increased risk of a cancer in a subject includes the steps of obtaining a blood sample from the subject and determining, in the blood sample, a level of two or more of the polypeptides selected from the group consisting of VNN2, KCNJ15, SERPINB2, CREB5, ICAM3, NFE2, MNDA, PXN, FCAR, TSHZ3, NRG1, ALOX5AP, PAD14, PAD12, QPC, VNN1, SERPINB10, CLEC4D, TREM1, CLEC4E, CD82, MGAM, TMEM45B and VNN3, wherein an increase in the level of two or more of the polypeptides compared to a control level is indicative of an increased risk of cancer in the subject.
FILED	Wednesday, June 24, 2015
APPL NO	15/321894
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/57484 (20130101) Original (OR) Class G01N 33/57488 (20130101) G01N 2800/50 (20130101)
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10288704 — Two-dimensional semi-LASER correlation spectroscopy with well-maintained cross peaks

US 10288704	Yang
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Shaolin Yang (Chicago, Illinois)
ABSTRACT	A sLASER-first-COSY sequence is disclosed. After a delay time, Δ₁, from application of a first 90° radio frequency (RF) pulse, a first pair of adiabatic full-passage (AFP) pulses are applied to an object in a MRI scanner. The first 90° RF pulse is a non-adiabatic slice-selective 90° RF pulse and the first pair of AFP pulses is separated by an inter-pulse time interval, Δ₂. A second pair of AFP pulses, separated by the time Δ₂, is then applied, followed by a second 90° RF pulse. The second 90° RF pulse is a non-adiabatic non-slice-selective 90° RF pulse. MR signal is acquired after an echo time (TE) from application of the excitation RF pulse. The present method may achieve intended full magnetization transfer between a coupled spin pair of a metabolite and maintain metabolite cross peak intensity of a coupled spin pair of a metabolite in the object.
FILED	Friday, April 04, 2014
APPL NO	14/782474
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/485 (20130101) G01R 33/4633 (20130101) G01R 33/4833 (20130101) Original (OR) Class
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10288814 — Variable spatial offset fiber optic probe for optical spectography and imaging

US 10288814	Bi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S)	Xiaohong Bi (Pearland, Texas); Zhiyong Wang (Sugar Land, Texas)
ABSTRACT	Apparatus and method for optical spectroscopy and/or imaging with a variable fiber offset. An optical probe includes one or more first optical fibers, one or more second optical fibers, and one or more actuators. The first optical fibers are to deliver light to an object. The second optical fibers are to collect light emitted from the object. The actuators are configured to change a distance between the first optical fibers and the second optical fiber while the object is being illuminated by light emitted from the first optical fibers.
FILED	Thursday, March 24, 2016
APPL NO	15/080256
ART UNIT	2883 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/4504 (20130101) A61B 2562/0233 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/49 (20130101) G01N 21/65 (20130101) G01N 2201/0846 (20130101) Optical Elements, Systems, or Apparatus G02B 6/00 (20130101) G02B 6/3504 (20130101) Original (OR) Class G02B 6/3578 (20130101)
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10289070 — Holograms using birefringent lenses

US 10289070	Brooker et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	CellOptic, Inc. (Rockville, Maryland)
ASSIGNEE(S)	Cell-Optic, Inc. (Rockville, Maryland)
INVENTOR(S)	Gary Brooker (Rockville, Maryland); Nisan Siegel (Silver Spring, Maryland)
ABSTRACT	Techniques to improve image quality in holography utilizing lenses made from materials with non-quantized anisotropic electromagnetic properties, such as birefringent materials, to advantageously split an incoming beam of light into two coincident beams with different focal lengths that interfere with one another and thus create holograms free of electro-optical or pixelated devices are disclosed. Corresponding systems, methods and apparatuses are described.
FILED	Thursday, August 04, 2016
APPL NO	15/228386
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 5/3083 (20130101) Holographic Processes or Apparatus G03H 1/041 (20130101) Original (OR) Class G03H 1/0443 (20130101) G03H 1/0866 (20130101) G03H 2001/0445 (20130101) G03H 2001/0452 (20130101) G03H 2223/17 (20130101)
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10289650 — Active stability devices and systems for mobile devices

US 10289650	Pearlman et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburg, Pennsylvania); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Jonathan L. Pearlman (Pittsburgh, Pennsylvania); Jonathan Aaron Duvall (Pittsburgh, Pennsylvania); Benjamin Todd Gebrosky (Gibsonia, Pennsylvania); Rory Alan Cooper (Gibsonia, Pennsylvania)
ABSTRACT	A system for use with a mobile device includes at least one sensor to sense a variable related to tilting of the mobile device and at least one activatable system in operative connection with the sensor. The at least one activatable system increases stability of the mobile device upon actuation/change in state thereof on the basis of data measured by the at least one sensor. A variable related to tilting includes variables that indicate concurrent, actual tilting as described herein as well as variables predictive of imminent tilting. Activatable systems hereof change state upon actuation or activation to increase stability of the mobile device by reducing, eliminating or preventing tilting.
FILED	Thursday, September 22, 2016
APPL NO	15/273116
ART UNIT	3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/00 (20130101) A61G 5/043 (20130101) A61G 5/063 (20130101) A61G 5/068 (20130101) A61G 5/128 (20161101) A61G 5/1054 (20161101) A61G 5/1089 (20161101) A61G 2203/14 (20130101) A61G 2203/42 (20130101) Electric Digital Data Processing G06F 17/00 (20130101) Original (OR) Class
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10289802 — Spanning-tree progression analysis of density-normalized events (SPADE)

US 10289802	Qiu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Peng Qiu (Houston, Texas); Andrew J. Gentles (San Jose, California); Sylvia K. Plevritis (Palo Alto, California); Garry Nolan (Palo Alto, California); Karen Sachs (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Peng Qiu (Houston, Texas); Andrew J. Gentles (San Jose, California); Sylvia K. Plevritis (Palo Alto, California); Garry Nolan (Palo Alto, California); Karen Sachs (Palo Alto, California)
ABSTRACT	Methods and systems for determining progression and other characteristics of microarray expression levels and similar information, alternatively using a network or communications medium or tangible storage medium or logic processor.
FILED	Friday, March 02, 2012
APPL NO	13/411492
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Electric Digital Data Processing G06F 19/20 (20130101) G06F 19/24 (20130101) Original (OR) Class G06F 19/26 (20130101)
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10290076 — System and method for automated initialization and registration of navigation system

US 10290076	Kadoury et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institutes of Health Clinical Center (NIHCC) U.S. Public Health Service (USPHS)
APPLICANT(S)	Samuel Kadoury (Olney, Maryland); Jochen Kruecker (Washington, District of Columbia); James Robertson Jago (Seattle, Washington); Bradford Johns Wood (Potomac, Maryland); Antoine Collet-Billon (Paris, France); Cecile Dufour (Paris, France)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Koninklijke Philips N.V. (Eindhoven, Netherlands)
INVENTOR(S)	Samuel Kadoury (Olney, Maryland); Jochen Kruecker (Washington, District of Columbia); James Robertson Jago (Seattle, Washington); Bradford Johns Wood (Potomac, Maryland); Antoine Collet-Billon (Paris, France); Cecile Dufour (Paris, France)
ABSTRACT	A system and method for image registration includes tracking (508) a scanner probe in a position along a skin surface of a patient. Image planes corresponding to the position are acquired (510). A three-dimensional volume of a region of interest is reconstructed (512) from the image planes. A search of an image volume is initialized (514) to determine candidate images to register the image volume with the three-dimensional volume by employing pose information of the scanner probe during image plane acquisition, and physical constraints of a pose of the scanner probe. The image volume is registered (522) with the three-dimensional volume.
FILED	Friday, March 02, 2012
APPL NO	14/002132
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 8/5261 (20130101) A61B 90/36 (20160201) A61B 2034/2046 (20160201) A61B 2090/365 (20160201) A61B 2090/367 (20160201) A61B 2090/378 (20160201) Image Data Processing or Generation, in General G06T 3/0068 (20130101) Original (OR) Class G06T 11/008 (20130101) G06T 15/08 (20130101)
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10290200 — Speech therapeutic devices and methods

US 10290200	Zhong et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Xuan Zhong (Tempe, Arizona); William Yost (Scottsdale, Arizona); Michael Dorman (Scottsdale, Arizona); Julie Liss (Scottsdale, Arizona); Visar Berisha (Tempe, Arizona)
ABSTRACT	Disclosed herein are speech therapeutic devices and methods. In one aspect, the speech therapeutic device includes audio input circuitry, signal processing circuitry, and stimulus circuitry. In certain embodiments, the audio input circuitry is configured to provide an input signal that is indicative of speech provided by a user and the signal processing circuitry is configured to utilize a reconfigurable rule that includes a condition, receive the input signal, process the input signal using the reconfigurable rule, and provide an alert signal responsive to attainment of the condition. The stimulus circuitry is configured to receive the alert signal and provide a stimulus to the user. The signal processing circuitry is additionally configured to (i) receive the reconfigurable rule from a communication network, and/or (ii) generate a record indicative of the alert signal, store the record in a memory, and send the record to a communication network.
FILED	Monday, July 16, 2018
APPL NO	16/035985
ART UNIT	2685 — Selective Communication
CURRENT CPC	Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) Original (OR) Class Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/00 (20130101) G09B 19/04 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/78 (20130101) G10L 2025/783 (20130101)
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Department of Defense (DOD)

10285394 — Floating pier, pinniped deterrent system

US 10285394	Granger et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Brian J Granger (San Diego, California); William A Chambers (Jamul, California); Kelly G Krueger (La Mesa, California); John E Hoopes (San Diego, California)
ABSTRACT	A system for deterring pinnipeds comprising a plurality of connected tracks interspersed with expansion joints, wherein the tracks and expansion joints are operatively coupled via connector keys that fit into a recessed channel running underneath the tracks and expansion joints, the tracks and expansion joints having electrically insulated recessed channels allowing for conductive wire to run throughout the tracks and expansion joints, the expansion joints further comprising two wells allowing for excess wire to be coiled and housed, acting as a spring and allowing for expansion, and the wire is connected to a power source.
FILED	Wednesday, October 21, 2015
APPL NO	14/919499
ART UNIT	3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 29/10 (20130101) A01M 29/24 (20130101) Original (OR) Class General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/72 (20130101) E04B 1/6803 (20130101)
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10285601 — Detection and monitoring of atrial fibrillation

US 10285601	Chon et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Worcester Polytechnic Institute (Worcester, Massachusetts)
ASSIGNEE(S)	Worcester Polytechnic Institute (Worcester, Massachusetts)
INVENTOR(S)	Ki H. Chon (Worcester, Massachusetts); Jowoon Chong (Worcester, Massachusetts)
ABSTRACT	A real-time arrhythmia discrimination method is used in smartphones, which can discriminate between NSR, AF, PACs and PVCs using pulsatile time series collected from a smartphone's camera. To increase the sensitivity of AF detection and add the new capabilities of PVC and PAC identification, the arrhythmia discrimination method of these teachings combines Root Mean Square of Successive RR Differences (RMSSD), Shannon Entropy (ShE) and turning point ratio (TPR), with the Poincare plot, and utilizes the features of pulse rise/fall time and amplitude for arrhythmia discrimination.
FILED	Tuesday, May 22, 2018
APPL NO	15/985912
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0464 (20130101) A61B 5/02405 (20130101) Original (OR) Class A61B 5/6898 (20130101) A61B 5/7282 (20130101)
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10285844 — Rapid setting composite article

US 10285844	Tomblin et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Wichita State University (Wichita, Kansas); Commercial Chemistries, LLC (Cottonwood Heights, Utah)
ASSIGNEE(S)	Wichita State University (Wichita, Kansas); Commercial Chemistries, LLC (Cottonwood Heights, Utah)
INVENTOR(S)	John S. Tomblin (Wichita, Kansas); Thomas Aldag (Wichita, Kansas); William T. McCarvill (Cottonwood Heights, Utah); Kimberly M. Reuter (Wichita, Kansas); Joel D. White (Wichita, Kansas); Andrea C. Meyer (Bel Aire, Kansas)
ABSTRACT	A fiber-reinforced composite article useful in supporting or immobilizing an injured body part is disclosed. The composite is a multi-layer, flexible precursor including fiber reinforcement plies, which can be rapidly cured into a rigid body using a thermosetting resin. Methods of making and using the same are also disclosed, along with kits containing such composite articles.
FILED	Monday, October 06, 2014
APPL NO	15/027984
ART UNIT	3786 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/01 (20130101) A61F 5/0585 (20130101) A61F 5/05825 (20130101) Original (OR) Class A61F 5/05841 (20130101) A61F 13/04 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/08 (20130101) A61L 15/12 (20130101) A61L 15/12 (20130101) A61L 15/12 (20130101) A61L 15/14 (20130101) A61L 15/125 (20130101) A61L 15/125 (20130101) Compositions of Macromolecular Compounds C08L 33/10 (20130101) C08L 33/10 (20130101) C08L 35/04 (20130101)
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10286016 — Compositions and methods for treating gonorrhea

US 10286016	Kim et al.
FUNDED BY	Department of Defense (DOD) Uniformed Services University of the Health Sciences (USUHS) Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE HENRY M. JACKSON FOUDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland)
INVENTOR(S)	Won Jong Kim (Tucson, Arizona); Maria Auxilio Rendón-Espinosa (Tucson, Arizona); Magdalene Yh So (Tucson, Arizona); Maira Goytia (Atlanta, Georgia); Ann Jerse (Bethesda, Maryland); Dustin Higashi (Notre Daem, Indiana)
ABSTRACT	The present invention relates to compositions and methods for preventing and/or treating gonorrhea. In particular, the present invention provides compositions comprising an effective amount of a commensal species of Neisseria (e.g., an effective amount of an extract of a commensal species of Neisseria), wherein such compositions are capable of inhibiting the growth of Neisseria gonorrhoeae.
FILED	Wednesday, September 02, 2015
APPL NO	15/508409
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/02 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 14/22 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101)
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10286930 — Instrumented rail system

US 10286930	Simon et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Sea Systems Command (NAVSEA) Johns Hopkins University Applied Physics Laboratory (JH APL)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Daniel H. Simon (Eldersburg, Maryland); Benjamin B. Alvarez (Hanover, Maryland); William A. Irizarry-Cruz (Odenton, Maryland); Todd M. Gustafson (West Friendship, Maryland); Abraham Rajan (Laurel, Maryland); Frederick Warren LeBlanc (Coconut Creek, Florida); Warren E. Zander (Millersville, Maryland)
ABSTRACT	A deployable vehicle for an instrumented rail system includes a first locomotion module having a first mobility assembly configured to engage a first rail, a second locomotion module having a second mobility assembly configured to engage a second rail, an adjustable frame extendable between the first and second locomotion modules by a distance corresponding to the distance between the first and second rails, and a sensor module removably attachable to the frame. The sensor module includes a sensor suite having a plurality of sensors for gathering data while the vehicle is deployed. The sensor module includes a communications module having a first radio configured to enable the vehicle to establish at least a first communication link with a remotely located mobile base station, and a second radio configured to establish a second communication link with the remotely located mobile base station.
FILED	Tuesday, April 05, 2016
APPL NO	15/090636
ART UNIT	3617 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Body Details or Kinds of Railway Vehicles B61D 15/12 (20130101) Original (OR) Class Auxiliary Equipment Specially Adapted for Railways, Not Otherwise Provided for B61K 9/08 (20130101) Guiding Railway Traffic; Ensuring the Safety of Railway Traffic B61L 15/009 (20130101) B61L 15/0027 (20130101) B61L 15/0081 (20130101) B61L 23/04 (20130101) B61L 23/041 (20130101) B61L 23/044 (20130101) B61L 23/045 (20130101) B61L 23/047 (20130101) B61L 23/048 (20130101) B61L 25/025 (20130101) B61L 27/0077 (20130101) B61L 27/0088 (20130101) Pictorial Communication, e.g Television H04N 5/247 (20130101)
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10286983 — Chevron ribbon fairing apparatus and method for hydrodynamic vibration and drag reduction

US 10286983	Coakley
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	David B. Coakley (Alexandria, Virginia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	David B. Coakley (Alexandria, Virginia)
ABSTRACT	The invention is a chevron ribbon fairing that reduces hydrodynamic drag on marine cables towed by a vessel. The fairing is the shape of a “V,” with an angle between the legs of the “V” chosen on the basis of the predicted cable angle relative to the flow. The chevron angle is twice the cable angle. The tip of chevron ribbon fairing is woven into the outer armor strands of the steel cable or molded to a jacketed cable. When the cable is at shallow angles to the fluid flow, the fairing aligns with the flow, a presents a reduced cross sectional area to the fluid flow behind the towed cable. The chevron design allows the ribbon to naturally align with the fluid flow even as the ribbon rotates about its axis. This ensures a reduction in tangential drag regardless of the level of cable tension.
FILED	Friday, September 29, 2017
APPL NO	15/719886
ART UNIT	3617 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Ships or Other Waterborne Vessels; Equipment for Shipping B63B 21/663 (20130101) Original (OR) Class
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10287022 — Pressure activated release for deployment of surface, aerial and subsea payloads

US 10287022	Lloyd et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	SPAWAR Systems Center Pacific (San Diego, California)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jeffrey M. Lloyd (San Diego, California); Brandon J. Wiedemeier (San Diego, California)
ABSTRACT	A pressure activated release system and method are disclosed for deployment of surface, aerial and subsea payloads. The system and method include a payload release switch that is activated, without human intervention, by a pressure differential. The system and method also includes a payload release mechanism having an unreleased configuration at pressures below a specified pressure. The release mechanism has a released configuration at pressures above the specified pressure. The switch causes the release mechanism to move from the unreleased configuration to the released configuration.
FILED	Monday, August 29, 2016
APPL NO	15/250418
ART UNIT	3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 17/38 (20130101) Original (OR) Class Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 35/26 (20130101)
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10287170 — Ultrapure synthetic carbon materials

US 10287170	Feaver et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	BASF SE (Ludwigshafen, Germany)
ASSIGNEE(S)	BASF SE (Ludwigshafen, Germany)
INVENTOR(S)	Aaron M. Feaver (Seattle, Washington); Henry R. Costantino (Woodinville, Washington); William D. Scott (Seattle, Washington)
ABSTRACT	The present application is generally directed to ultrapure synthetic carbon materials having both high surface area and high porosity, ultrapure polymer gels and devices containing the same. The disclosed ultrapure synthetic carbon materials find utility in any number of devices, for example, in electric double layer capacitance devices and batteries. Methods for making ultrapure synthetic carbon materials and ultrapure polymer gels are also disclosed.
FILED	Thursday, January 12, 2017
APPL NO	15/405104
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 32/00 (20170801) C01B 32/05 (20170801) C01B 32/318 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/12 (20130101) C01P 2006/80 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/042 (20130101) H01G 11/24 (20130101) H01G 11/32 (20130101) H01G 11/34 (20130101) H01G 11/48 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/96 (20130101) H01M 4/583 (20130101) H01M 10/06 (20130101) H01M 10/052 (20130101) H01M 2220/20 (20130101) H01M 2220/30 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101)
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10287237 — Polymeric materials made from vanillin

US 10287237	Wright et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Michael E. Wright (Ridgecrest, California); Benjamin G. Harvey (Ridgecrest, California)
ABSTRACT	A method for converting vanillin to bis(cyanate) ester monomers, comprising treating vanillin with a reductive coupling agent to form at least one olefin. The olefin or olefins are treated with hydrogen and a metal catalyst to hydrogenate said olefin. The hydrogenated olefin or olefins are treated with at least one cyanogen halide and a base in an organic solvent to afford at least one olefin monomer. The olefin monomer or monomers are purified by recrystallization or precipitation from an organic solvent.
FILED	Thursday, October 12, 2017
APPL NO	15/782223
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 37/002 (20130101) C07C 37/003 (20130101) C07C 37/16 (20130101) C07C 253/04 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/38 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 13/002 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 13/345 (20130101) D06M 2101/40 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10287283 — Read-through compound prodrugs suppressing premature nonsense mutations

US 10287283	Bertoni et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Carmen Bertoni (Los Angeles, California); Jasbir Singh (Naperville, Illinois)
ABSTRACT	Premature termination codon readthrough prodrug compounds, compositions thereof, and methods of making and using the same are provided. In certain embodiments, the compounds are of Formula Ia or a pharmaceutically acceptable salt, solvate, polymorph, hydrate, ester, isomer, stereoisomer, or tautomer thereof, wherein R, A and W are as described herein.
FILED	Monday, September 17, 2018
APPL NO	16/133230
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 417/06 (20130101) Original (OR) Class C07D 417/14 (20130101)
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10287355 — Methods and compositions for modulating lymphangiogenesis, E.G., to treat transplant rejection, in a subject

US 10287355	Chen
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Lu Chen (Berkeley, California)
ABSTRACT	Methods of modulating the occurrence of lymphangiogenesis in a subject are provided. In some instances, the method is a method of treating transplant rejection in the subject. Aspects of the methods include administering to the subject an effective amount of: a first antagonist for a tyrosine kinase receptor and a second antagonist for an integrin receptor. In some embodiments, the methods include enhancing survival of transplanted tissue in a subject. Aspects of the invention further include compositions, e.g., pharmaceutical compositions and kits that find use in methods of the invention.
FILED	Monday, June 13, 2016
APPL NO	15/181268
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/2842 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 2317/76 (20130101)
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10287495 — Photoluminescent nanodiamond material

US 10287495	Shenderova et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of the Navy (DON)
APPLICANT(S)	International Technology Center (Raleigh, North Carolina)
ASSIGNEE(S)
INVENTOR(S)	Olga Alexander Shenderova (Raleigh, North Carolina); Igor Vlasov (Zukovskii, Russian Federation); Suzanne Ani-Ciftan Hens (Durham, North Carolina); Vesna Borjanovic (Cary, North Carolina)
ABSTRACT	Photoluminescent nanodiamond particles of dynamic synthesis have enhanced photoluminescent properties produced as a result of minimizing the nitrogen content of impurities or imperfections in the nanodiamond lattice and by location of photoluminescent structures on the outer surface of the nanodiamond particles. This inhibits suppression (i.e. inactivity) of emission and enhances the intensity of the emission. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
FILED	Tuesday, December 22, 2015
APPL NO	14/978184
ART UNIT	1788 — Miscellaneous Articles, Stock Material
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/02 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/65 (20130101) Original (OR) Class
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10287573 — Combinatorial DNA taggants and methods of preparation and use thereof

US 10287573	Macula
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Research Laboratory (AFRL) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	JEANSEE LLC (Geneseo, New York)
ASSIGNEE(S)	JEANSEE LLC (Geneseo, New York)
INVENTOR(S)	Anthony J. Macula (Geneseo, New York)
ABSTRACT	DNA taggants in which the nucleotide sequences are defined according to combinatorial mathematical principles. Methods of defining nucleotide sequences of the combinatorial DNA taggants, and using such taggants for authentication and tracking and tracing an object or process are also disclosed.
FILED	Monday, April 14, 2014
APPL NO	14/251690
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6876 (20130101) C12Q 2563/185 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10287587 — Prostate cancer-specific alterations in ERG gene expression and detection and treatment methods based on those alterations

US 10287587	Srivastava et al.
FUNDED BY	Department of Defense (DOD) Uniformed Services University of the Health Sciences (USUHS) Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland)
ASSIGNEE(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
INVENTOR(S)	Shiv Srivastava (Potomac, Maryland); Albert Dobi (Rockville, Maryland); Taduru Sreenath (Germantown, Maryland); Gyorgy Petrovics (Bethesda, Maryland); Chen Sun (Bethesda, Maryland)
ABSTRACT	The disclosure describes alterations in ERG gene expression. ERG isoforms and promoter sequence of the ERG gene that are involved in, or associated with, prostate cancer are provided. The disclosure further provides therapeutic compositions and methods of detecting, diagnosing, prognosing, and treating prostate cancer, including biomarkers for detecting the expression of two or more of the following genes: PSA/KLK3, PMEPA1, NKX3.1, ODC1, AMD1, and ERG.
FILED	Thursday, August 22, 2013
APPL NO	13/974007
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2320/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101)
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10287897 — Turbine rotor blade assembly and method of assembling same

US 10287897	Paige, II et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Department of the Navy (DON)
APPLICANT(S)	Anthony Reid Paige, II (Cincinnati, Ohio); Michael James Verrilli (Loveland, Ohio); Joshua Brian Jamison (Middletown, Ohio); Mark Eugene Noe (Morrow, Ohio); Paul Izon (Morrow, Ohio); Mark Willard Marusko (Springboro, Ohio)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Anthony Reid Paige, II (Cincinnati, Ohio); Michael James Verrilli (Loveland, Ohio); Joshua Brian Jamison (Middletown, Ohio); Mark Eugene Noe (Morrow, Ohio); Paul Izon (Morrow, Ohio); Mark Willard Marusko (Springboro, Ohio)
ABSTRACT	A rotor blade assembly for a rotor of a gas turbine engine having an axis of rotation includes a shank portion formed from a ceramic matrix composite (CMC) material. The rotor blade assembly also includes a platform portion formed from a substantially similar CMC material as that of the shank portion. The platform portion is coupled to the shank portion. The platform portion and the shank portion cooperate to at least partially define two opposing side portions of the rotor blade assembly. The opposing side portions are angularly separated with respect to the axis of rotation. The rotor blade assembly further includes a damper retention apparatus. The damper retention apparatus is coupled to the shank portion. The damper retention apparatus includes at least one angled bracket apparatus extending toward a circumferentially adjacent rotor blade assembly.
FILED	Thursday, September 08, 2011
APPL NO	13/228142
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/22 (20130101) F01D 5/284 (20130101) Original (OR) Class F01D 5/3007 (20130101) F01D 11/006 (20130101) F01D 11/08 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2300/6033 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49321 (20150115)
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10287900 — Incident tolerant turbine vane cooling

US 10287900	Slavens et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Thomas N. Slavens (Vernon, Connecticut); Matthew A. Devore (Cromwell, Connecticut)
ABSTRACT	A disclosed turbine vane assembly for a gas turbine engine includes an airfoil including a pressure side and a suction side that extends from a leading edge toward a trailing edge. The airfoil is rotatable about an axis transverse to an engine longitudinal axis and includes a forward chamber within the airfoil and in communication with a cooling air source, a forward impingement baffle defining a pre-impingement cavity within the forward chamber. The pre-impingement cavity is split into a leading edge cavity, pressure side cavity and a suction side cavity defined between an inner surface of the forward chamber and an outer surface of the forward impingement baffle.
FILED	Friday, October 17, 2014
APPL NO	15/028572
ART UNIT	3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) F01D 5/188 (20130101) F01D 9/023 (20130101) Original (OR) Class F01D 9/041 (20130101) F01D 17/162 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/121 (20130101) F05D 2260/201 (20130101)
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10287904 — Multi-element inner shroud extension for a turbo-machine

US 10287904	Filipenco et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Victor G. Filipenco (Portland, Connecticut); Anthony R. Bifulco (Ellington, Connecticut)
ABSTRACT	A turbine engine is disclosed and includes an airflow passage including an inner surface defined by a main shroud and a shroud extension. A flow splitter is disposed radially outward of the inner surface and axially overlapping the shroud extension. The turbine engine further includes a rotor including a blade proximate the shroud extension and an annular gap defined between the shroud extension and the blade of a first axial length less than a second axial length between the blade and an end of the flow splitter.
FILED	Tuesday, November 04, 2014
APPL NO	15/035258
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 9/02 (20130101) F01D 9/04 (20130101) F01D 11/001 (20130101) Original (OR) Class F01D 25/24 (20130101) F01D 25/243 (20130101) F01D 25/246 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 7/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/60 (20130101) F05D 2230/64 (20130101) F05D 2230/642 (20130101) F05D 2240/11 (20130101) F05D 2260/30 (20130101)
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10288234 — Hand-held UV stimulator

US 10288234	Whelan et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Jenna M. Whelan (Windham, New Hampshire); Fernando Hernandez (Epping, New Hampshire); Jared Kondratuk (Amherst, New Hampshire); Denise X. Zhang (Sudbury, Massachusetts)
ABSTRACT	A system and method for stimulating light sensors (e.g., UV) using a hand-held stimulator. The hand-held stimulator is portable and configurable to store a plurality of routines comprising various light signatures. In some cases, the signature is a threat signature (e.g., missile, RPG, and/or gunfire) and the stimulator is used as part of system integration, field and flight line, and/or lab testing for systems utilizing light sensors.
FILED	Wednesday, November 07, 2018
APPL NO	16/182853
ART UNIT	2884 — Optics
CURRENT CPC	Lighting Devices or Systems Thereof, Being Portable or Specially Adapted for Transportation F21L 14/023 (20130101) Original (OR) Class Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 23/007 (20130101) F21V 23/0414 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) G01J 5/10 (20130101) Measurement of Nuclear or X-radiation G01T 1/208 (20130101)
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10288395 — Nosecone inverted F antenna for S-band telemetry

US 10288395	Barton
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Aaron Elie Barton (Oswego, New York)
ABSTRACT	An inverted F antenna for use in a projectile includes a ground plane and a radiating element oriented orthogonal to the ground plane and centered on the ground plane. The radiating element includes a ground stub trace having a relatively thick width, a meandering trace with a vertical orientation and a relatively high ground clearance and a feed trace having a tapered head.
FILED	Tuesday, June 06, 2017
APPL NO	15/614971
ART UNIT	3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Weapon Sights; Aiming F41G 7/306 (20130101) F41G 7/346 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/365 (20130101) Original (OR) Class F42B 15/01 (20130101) F42B 30/006 (20130101) Antennas, i.e Radio Aerials H01Q 1/281 (20130101) H01Q 1/286 (20130101)
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10288428 — Velocity selective thermal atomic beam inertial sensor

US 10288428	Cingoz et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	AOSense, Inc. (Sunnyvale, California)
ASSIGNEE(S)	AOSense, Inc. (Sunnyvale, California)
INVENTOR(S)	Arman Cingoz (Sunnyvale, California); Miao Zhu (San Jose, California); Miroslav Y. Shverdin (Mountain View, California); Matthew Cashen (Gilroy, California)
ABSTRACT	An atom interferometer device for inertial sensing includes one or more thermal atomic sources, a state preparation laser, a set of lasers, and a detection laser. The one or more thermal atomic sources provide one or more atomic beams. A state preparation laser is disposed to provide a state preparation laser beam nominally perpendicular to each of the one or more atomic beams. A set of lasers is disposed to provide interrogation laser beams that interrogate the one or more atomic beams to assist in generating atom interference. A detection laser is disposed to provide a detection laser beam, which is angled at a first angle to the each of the one or more atomic beams in order to enhance the dynamic range of the device by enabling velocity selectivity of atoms used in detecting the atom interference.
FILED	Monday, February 12, 2018
APPL NO	15/894488
ART UNIT	2881 — Optics
CURRENT CPC	Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/58 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101)
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10288429 — Apparatus and method for diminishing mode lock induced error in stimulated brillouin scattering waveguide ring laser gyroscopes

US 10288429	Qiu et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S)	Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S)	Tiequn Qiu (Glendale, Arizona); Jianfeng Wu (Tucson, Arizona); Matthew Wade Puckett (Scottsdale, Arizona)
ABSTRACT	In one embodiment, a method is provided. The method comprises transmitting a first laser pump signal to an optical resonator; adjusting a frequency of the first laser pump signal; generating a first order Stokes signal from the first laser pump signal in an optical resonator; measuring a first beat signal frequency; ceasing transmission of the first laser pump signal to the optical resonator; transmitting a second laser pump signal to the optical resonator; adjusting a frequency of the second laser pump signal; generating a first order Stokes signal from the second laser pump signal in the optical resonator; and measuring a second beat signal frequency; ceasing transmission of the second laser pump signal to the optical resonator.
FILED	Thursday, June 01, 2017
APPL NO	15/611742
ART UNIT	2886 — Optics
CURRENT CPC	Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/68 (20130101) Original (OR) Class G01C 19/662 (20130101) G01C 19/667 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/302 (20130101) H01S 3/1024 (20130101)
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10288492 — Fast response temperature sensor

US 10288492	Arwatz et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Gilad Arwatz (Princeton, New Jersey); Yuyang Fan (Princeton, New Jersey); Carla Bahri (Princeton, New Jersey); Marcus Hultmark (Princeton, New Jersey)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S)	Gilad Arwatz (Princeton, New Jersey); Yuyang Fan (Princeton, New Jersey); Carla Bahri (Princeton, New Jersey); Marcus Hultmark (Princeton, New Jersey)
ABSTRACT	In the present invention, a temperature sensor system and methods for using the apparatus are disclosed, the temperature sensor having particular thermal-inertia time constants. More specifically, the temperature sensor system comprises prongs having a defined l/d ratio range, a sensing element having a low volume, and constant-current circuitry.
FILED	Friday, October 07, 2016
APPL NO	15/287808
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 1/18 (20130101) Original (OR) Class G01K 7/18 (20130101) G01K 13/02 (20130101)
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10288497 — Apparatus for destructive event testing of chemical energy systems using adaptive heat flow testing systems and related methods

US 10288497	Ubelhor et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Surface Warfare Center (NSWC)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Ryan Ubelhor (Solsberry, Indiana); Daniel Ellison (Odon, Indiana); Cecilia Pierce (Bedford, Indiana)
ABSTRACT	Apparatus and methods are provided for providing flexible and repairable testing capabilities, including destructive testing, for systems that generate or absorb heat such as energy storage systems. One embodiment can include a temperature bath structure adapted to contain and maintain a fluid bath at a predetermined temperature, an outer containment structure adapted to insert into the temperature bath structure, heat sinks, thermal sensor assemblies, and an internal containment structure where the thermal sensor assemblies, heat sinks removeably attach to different sections of the inner containment structure so as to measure heat flow into or out of the inner containment structure's different sections, and a test cell enclosure which is adapted to contain forces and output from destructive testing of samples. Embodiments of the invention enable rapid insertion/removal of samples as well as replacement of sections of the system including thermal sensor assemblies as well as enabling separate thermal measurements associated with different sections of a sample under test.
FILED	Tuesday, August 02, 2016
APPL NO	15/226604
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/00 (20130101) G01K 19/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/20 (20130101) G01N 25/32 (20130101)
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10288563 — Sensor platform based on toroidal resonances for rapid detection of biomolecules

US 10288563	Ahmadivand et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Arash Ahmadivand (Miami, Florida); Raju Sinha (Miami, Florida); Burak Gerislioglu (Miami, Florida); Nezih Pala (Fort Lauderdale, Florida)
ASSIGNEE(S)	The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S)	Arash Ahmadivand (Miami, Florida); Raju Sinha (Miami, Florida); Burak Gerislioglu (Miami, Florida); Nezih Pala (Fort Lauderdale, Florida)
ABSTRACT	A plasmonic resonator can include: a substrate; a central resonator on the substrate; a first curved resonator disposed on the substrate and disposed at a first side of the central resonator; and a second curved resonator disposed on the substrate and disposed at a second side of the central resonator, the first curved resonator and the second curved resonator being asymmetric to each other with respect to the central resonator, and the central resonator and at least one of the first and second curved resonators being made of different materials.
FILED	Monday, January 22, 2018
APPL NO	15/876481
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) Original (OR) Class G01N 21/3581 (20130101) G01N 33/56983 (20130101) G01N 2333/185 (20130101)
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10288572 — Apparatus for destructive event testing of chemical energy systems using highly portable and ease of access adaptive heat flow testing systems including replaceable and thermally isolated modular thermal sections each capable of independent measurements of a test article with improved ease of test article insertion and removal and related methods

US 10288572	Ellison et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Surface Warfare Center (NSWC)
APPLICANT(S)	The United States of America as represented by the SEC of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Daniel Ellison (Odon, Indiana); Ryan Ubelhor (Solsberry, Indiana); Cecilia Pierce (Bedford, Indiana)
ABSTRACT	Apparatus and methods are provided for providing flexible and repairable testing capabilities, including destructive testing, for systems that generate or absorb heat such as energy storage systems. One embodiment can include a heat exchange system adapted to contain and maintain a fluid at a predetermined temperature, thermally conductive tubing in direct intimate contact with a plurality of heat sinks, thermal sensor assemblies, and an sample vessel receiver structure where the thermal sensor assemblies, heat sinks removeably attach to different sections of the inner containment structure so as to measure heat flow into or out of the inner containment structure's different sections, and a test cell enclosure which is adapted to contain forces and output from destructive testing of samples. Embodiments of the disclosure enable rapid insertion/removal of samples as well as replacement of sections of the system including thermal sensor assemblies as well as enabling separate thermal measurements associated with different sections of a sample under test.
FILED	Friday, August 04, 2017
APPL NO	15/669522
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/00 (20130101) G01K 17/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/20 (20130101) G01N 25/32 (20130101) Original (OR) Class
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10288588 — Prediction of fuel properties

US 10288588	Morris et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Robert E. Morris (Silver Spring, Maryland); Mark H. Hammond (Alexandria, Virginia); Kevin J. Johnson (Alexandria, Virginia); Jeffrey A. Cramer (Alexandria, Virginia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Robert E. Morris (Silver Spring, Maryland); Mark H. Hammond (Alexandria, Virginia); Kevin J. Johnson (Alexandria, Virginia); Jeffrey A. Cramer (Alexandria, Virginia)
ABSTRACT	A system is described that includes a known fuels database of data from gas chromatography-mass spectrometry analyses of a library of fuels with known fuel properties for a multiple known fuel samples. Gas chromatography-mass spectrometry equipment can acquire gas chromatography-mass spectrometry data for an unknown fuel sample. A metaspectrum module can accept and transform the gas chromatography-mass spectrometry data collected by the gas chromatography-mass spectrometry equipment for the unknown fuel sample into a single metaspectrum for the unknown fuel sample, wherein the metaspectrum is a quantitative representation of every compound detected in the unknown fuel sample. A correlation module can correlate the metaspectrum for the unknown fuel sample to a plurality of fuel properties of known fuel samples using a regression model to predict fuel properties for the unknown fuel sample. A reporting module can report the fuel properties for the unknown fuel sample to a user.
FILED	Tuesday, September 29, 2015
APPL NO	14/869944
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/7206 (20130101) Original (OR) Class G01N 30/8675 (20130101) G01N 33/2829 (20130101)
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10288595 — Water quality analysis system and method

US 10288595	Anderson et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Michael J. Anderson (Dumfries, Virginia); Clint B. Smith (Chantilly, Virginia); Andmorgan R. Fisher (Haymarket, Virginia); Tung Ly (Lorton, Virginia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia)
INVENTOR(S)	Michael J. Anderson (Dumfries, Virginia); Clint B. Smith (Chantilly, Virginia); Andmorgan R. Fisher (Haymarket, Virginia); Tung Ly (Lorton, Virginia)
ABSTRACT	The present invention provides a water quality analysis system capable of making multiple simultaneous measurements of different water quality parameters and saving or transmitting this data for analysis. A housing surrounds a data processor and a water sensor flow cell. The flow cell incorporates a channel through which a stream of water flows. Multiple probe bores within the flow cell house different sensor probes used to measure different water quality parameters of the stream. The data processor receives and digitizes data for the different water quality parameters.
FILED	Wednesday, May 20, 2015
APPL NO	14/717314
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/1886 (20130101) Original (OR) Class G01N 33/1893 (20130101) G01N 2033/243 (20130101)
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10288811 — Optical switching between waveguides by adjacent resonant structure coupling

US 10288811	Kielpinski et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	Hewlett Packard Enterprise Development LP (Houston, Texas)
ASSIGNEE(S)	Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S)	David Kielpinski (Palo Alto, California); Shuren Hu (Palo Alto, California); Mir Ashkan Seyedi (Palo Alto, California); Thomas Van Vaerenbergh (Palo Alto, California); Gabriel Joel Mendoza (Palo Alto, California); Jason Pelc (Palo Alto, California)
ABSTRACT	Examples described herein relate to an optical switching device wherein a racetrack resonant structure is positioned to determine a frequency passband by coupling. In some examples, a first waveguide receives an input light signal. A second waveguide is positioned to enable the input light signal to couple between the first waveguide and the second waveguide through a first coupling gap. The racetrack resonant structure is positioned adjacent to the first coupling gap to enable the input light signal to couple between one of the first waveguide and the second waveguide and the racetrack resonant structure through a second coupling gap. Thus, the racetrack resonant structure is to determine the frequency passband such that a first portion of the input light signal that coincides with the frequency passband is output by the first waveguide, and a second portion of the input light signal that does not coincide with the frequency passband is output by the second waveguide.
FILED	Tuesday, December 05, 2017
APPL NO	15/831733
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/29338 (20130101) Original (OR) Class G02B 6/29343 (20130101) G02B 6/29395 (20130101)
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10288892 — Common aperture optical relay system

US 10288892	Mitchell
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Wavefront Research, Inc. (Bethlehem, Pennsylvania)
ASSIGNEE(S)	WAVEFRONT RESEARCH, INC. (Northampton, Pennsylvania)
INVENTOR(S)	Thomas A. Mitchell (Nazareth, Pennsylvania)
ABSTRACT	An optical relay system that is capable of re-imaging an image or a pupil from a shared location to two or more optical systems, or from two or more optical systems to a shared location is disclosed.
FILED	Monday, October 16, 2017
APPL NO	15/784455
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 5/28 (20130101) G02B 13/14 (20130101) G02B 17/0896 (20130101) G02B 27/141 (20130101) G02B 27/149 (20130101) G02B 27/1066 (20130101) Original (OR) Class
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10289761 — Method for modeling dynamic trajectories of guided, self-propelled moving bodies

US 10289761	McMahon
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Matthew D. McMahon (Damascus, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Matthew D. McMahon (Damascus, Maryland)
ABSTRACT	According to exemplary practice of the present invention, the dynamic trajectory of a moving body is incrementally modeled using temporal and spatial relationships between the body and the target that the body pursues. In each time step, the body has starting positional coordinates and ending positional coordinates. The horizontal travel distance is calculated by taking into account the body's speed and the body's horizontal distance from the target. The vertical travel distance is calculated by taking into account the body trajectory's spatial derivative and the body's horizontal travel distance. The body's time-step-ending positional coordinates thus reflect the change, in accordance with the horizontal travel distance and the vertical travel distance, relative to the body's time-step-starting positional coordinates. Each succeeding time step repeats the computations whereby the starting positional coordinates are the ending positional coordinates of the preceding time step.
FILED	Tuesday, December 17, 2013
APPL NO	14/109136
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class
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10289799 — Techniques for controlling spatial structure of nucleic acid structures based on lattice-free, three dimensional junction coordinates

US 10289799	Bathe et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Mark Bathe (Cambridge, Massachusetts); Keyao Pan (Cambridge, Massachusetts); Do-Nyun Kim (Seoul, South Korea)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Mark Bathe (Cambridge, Massachusetts); Keyao Pan (Cambridge, Massachusetts); Do-Nyun Kim (Seoul, South Korea)
ABSTRACT	Techniques for controlling nucleic acid structures include determining, for each junction type, values for parameters indicating ground-state geometry and both translational and rotational stiffness coefficients. Topological design data indicates a number of bases in each helix connected to corresponding junctions. Initial positions of each base are determined by connecting helices to junctions using the ground-state geometry and arbitrary coordinates not confined to lattice coordinates. Misalignment vectors each indicate a difference in coordinates and orientations between initial positions of a pair of bases that are not adjacent in the initial positions but are adjacent or coincident in the design data. Forces and moments at the junctions to reduce misalignment magnitudes are determined based on the translational and rotational stiffness coefficients at each junction. Position and orientation in 3D coordinates of each base are determined by reducing or eliminating the misalignment magnitudes and balancing forces and moments across the nanostructure.
FILED	Saturday, October 03, 2015
APPL NO	14/874417
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Electric Digital Data Processing G06F 19/16 (20130101) Original (OR) Class G06F 19/26 (20130101)
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10289819 — Active authentication of users

US 10289819	Stavrou et al.
FUNDED BY	Department of Homeland Security (DHS) Science and Technology Directorate (DHS-ST) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Kryptowire LLC (Fairfax, Virginia)
ASSIGNEE(S)	KRYPTOWIRE LLC (Fairfax, Virginia)
INVENTOR(S)	Angelos Stavrou (Fairfax, Virginia); Rahul Murmuria (Burke, Virginia); Ryan Johnson (Warrenton, Virginia); Daniel Barbara (Reston, Virginia)
ABSTRACT	Embodiments herein disclose a method and system for actively authenticating users of an electronic device in a continuous manner using a plurality of factors comprising of biometric modalities, power consumption, application usage, user interactions, user movement, and user location/travel.
FILED	Friday, August 12, 2016
APPL NO	15/236049
ART UNIT	2434 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/32 (20130101) G06F 21/316 (20130101) Original (OR) Class
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10289910 — System and method for performing real-time video object recognition utilizing convolutional neural networks

US 10289910	Chen et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Yang Chen (Westlake Village, California); Deepak Khosla (Camarillo, California)
ABSTRACT	Described is a system for real-time object recognition. During operation, the system extracts convolutional neural network (CNN) feature vectors from an input image. The input image reflects a scene proximate the system, with the feature vector representing an object in the input image. The CNN feature vector is matched against feature vectors stored in a feature dictionary to identify k nearest neighbors for each object class stored in the feature dictionary. The matching results in a probability distribution over object classes stored in the feature dictionary. The probability distribution provides a confidence score that each of the object classes in the feature dictionary are representative of the object in the input image. Based on the confidence scores, the object in the input image is then recognized as being a particular object class when the confidence score for the particular object class exceeds a threshold.
FILED	Thursday, January 05, 2017
APPL NO	15/399522
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00664 (20130101) Original (OR) Class G06K 9/6276 (20130101) Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) G06N 3/0472 (20130101) G06N 5/046 (20130101) G06N 99/005 (20130101)
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10290483 — Systems and methods for transfer of ions for analysis

US 10290483	Ouyang et al.
FUNDED BY	Department of Homeland Security (DHS) Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Zheng Ouyang (West Lafayette, Indiana); Robert Graham Cooks (West Lafayette, Indiana); Sandilya Venkata Garimella (West Lafayette, Indiana); Jason David Harper (Lafayette, Indiana); Nicholas Alan Charipar (Batavia, Indiana)
ABSTRACT	The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.
FILED	Thursday, May 24, 2018
APPL NO	15/988698
ART UNIT	2881 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/04 (20130101) H01J 49/10 (20130101) H01J 49/26 (20130101) H01J 49/0027 (20130101) H01J 49/0031 (20130101) H01J 49/40 (20130101) H01J 49/0404 (20130101) Original (OR) Class H01J 49/0409 (20130101) H01J 49/0422 (20130101) H01J 49/0459 (20130101) H01J 49/4215 (20130101)
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10290594 — Fragmenting computer chips

US 10290594	Cabral, Jr. et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Cyril Cabral, Jr. (Yorktown Heights, New York); Kenneth P. Rodbell (Sandy Hook, Connecticut)
ABSTRACT	A method comprising bonding a first substrate to a second substrate. The first substrate includes a layer of one or more pairs of reactive material. The method comprising triggering a reaction between the one or more pairs of reactive material and fragmenting the second substrate.
FILED	Thursday, July 28, 2016
APPL NO	15/222056
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 43/00 (20130101) C06B 45/10 (20130101) C06B 45/14 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/573 (20130101) H01L 23/576 (20130101) Original (OR) Class H01L 23/585 (20130101) H01L 27/2472 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/185 (20130101)
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10290767 — High efficiency visible and ultraviolet nanowire emitters

US 10290767	Mi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY (Montreal, Canada)
ASSIGNEE(S)	The Royal Institution for the Advancement of Learning/McGill University (Montreal, Quebec, Canada)
INVENTOR(S)	Zetian Mi (Verdun, Canada); Songrui Zhao (Montreal, Canada); Renjie Wang (Montreal, Canada)
ABSTRACT	GaN-based nanowire heterostructures have been intensively studied for applications in light emitting diodes (LEDs), lasers, solar cells and solar fuel devices. Surface charge properties play a dominant role on the device performance and have been addressed within the prior art by use of a relatively thick large bandgap AlGaN shell covering the surfaces of axial InGaN nanowire LED heterostructures has been explored and shown substantial promise in reducing surface recombination leading to improved carrier injection efficiency and output power. However, these lead to increased complexity in device design, growth and fabrication processes thereby reducing yield/performance and increasing costs for devices. Accordingly, there are taught self-organizing InGaN/AlGaN core-shell quaternary nanowire heterostructures wherein the In-rich core and Al-rich shell spontaneously form during the growth process.
FILED	Thursday, June 09, 2016
APPL NO	15/177608
ART UNIT	2895 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) Original (OR) Class H01L 33/007 (20130101) H01L 33/08 (20130101) H01L 33/18 (20130101) H01L 33/32 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/021 (20130101) H01S 5/1042 (20130101) H01S 5/4006 (20130101) H01S 5/32341 (20130101)
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10290797 — Method for producing high-temperature superconducting films having sharp charge doping discontinuities

US 10290797	Taylor
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Benjamin J. Taylor (Escondido, California)
ABSTRACT	A method includes providing a film having an initial uniform oxygen state on a substrate and annealing the film in a thermal gradient annealing device while applying a steady-state thermal gradient and a uniaxial pressure until the film comprises two or more discrete regions, where at least one of the regions has a final stabilized oxygen state different from the initial uniform oxygen state. The film is a high-temperature compound belonging to the class of compounds having a compositional form of R_1−yM_yBa₂Cu_3−zT_zO_x, where 6≤x≤7, where 0≤y≤1, where 0≤z≤1, where R comprises at least one of a rare earth and calcium, where M comprises at least one of a rare earth distinct from that of R and calcium if absent from R, where T comprises at least one of cobalt (Co), iron (Fe), nickel (Ni), and zinc (Zn).
FILED	Friday, July 01, 2016
APPL NO	15/200769
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/24 (20130101) H01L 39/126 (20130101) Original (OR) Class
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10290816 — Organic electroluminescent materials and devices

US 10290816	Forrest et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Stephen R. Forrest (Ann Arbor, Michigan); Jaesang Lee (Ann Arbor, Michigan); Quinn Burlingame (Ann Arbor, Michigan)
ABSTRACT	An organic light emitting device is disclosed whose emissive layer has a host material, a first emissive dopant, and a second dopant. The second dopant is an excited energy state managing dopant provided in an amount between 2-10 vol. % of the emissive layer and has a lowest triplet state energy level, T_M, that is higher than a lowest triplet state energy levels, T₁, of both the host and the first dopant and lower than the multiply-excited energy level, T*, of the first dopant.
FILED	Wednesday, November 09, 2016
APPL NO	15/347371
ART UNIT	2814 — Semiconductors/Memory
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/185 (20130101) C09K 2211/1007 (20130101) C09K 2211/1014 (20130101) C09K 2211/1029 (20130101) C09K 2211/1044 (20130101) C09K 2211/1092 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0061 (20130101) H01L 51/0072 (20130101) Original (OR) Class H01L 51/0074 (20130101) H01L 51/0085 (20130101) H01L 51/0087 (20130101) H01L 51/5004 (20130101) H01L 51/5016 (20130101) H01L 51/5024 (20130101) H01L 51/5028 (20130101) H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 51/5096 (20130101)
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10290944 — Efficient active multi-drive radiator

US 10290944	Bowers et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Steven Bowers (Duarte, California); Seyed Ali Hajimiri (La Canada, California)
ABSTRACT	An integrated Multi-Port Driven (MPD) antenna that can be driven at many points with different signals. An integrated MPD radiating source utilizing an 8-phase ring oscillator and eight power amplifiers to drive the MPD antenna at 161 GHz with a total radiated power of −2 dBm and a single element EIRP of 4.6 dBm has been demonstrated in silicon with single lobe well behaved radiation patterns closely matching simulation.
FILED	Tuesday, November 17, 2015
APPL NO	14/944089
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/48 (20130101) H01Q 11/04 (20130101) Original (OR) Class H01Q 25/04 (20130101)
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10291071 — Wireless power and data transfer for unmanned vehicles

US 10291071	Bana et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Viktor S. Bana (San Diego, California); Gregory W. Anderson (San Diego, California); Wayne P. Liu (San Diego, California); John D. Rockway (San Diego, California)
ABSTRACT	A system and method provide for wireless power and/or data transfer between devices, such as coils. A first device, operatively connected to an energy source, is positioned within a wireless transmission range of a second device, which may be operatively coupled to an unmanned vehicle. Power and/or data is wirelessly transferred to/from the energy source from/to the unmanned vehicle via the first device and the second device.
FILED	Tuesday, January 19, 2016
APPL NO	15/001101
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 50/12 (20160201) Original (OR) Class H02J 50/15 (20160201) H02J 50/90 (20160201)
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10291076 — Misalignment insensitive wireless power transfer with cylindrical, spherical and conical transmitter and receiver elements

US 10291076	Georgakopoulos
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Stavros Georgakopoulos (Miami, Florida)
ASSIGNEE(S)	The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S)	Stavros Georgakopoulos (Miami, Florida)
ABSTRACT	Wireless power transfer systems including wireless transmitter and receivers, which are insensitive to misalignment, are provided. A wireless power transfer system can include a first conductive loop that has cylindrical, conical, or spherical symmetry. The wireless power transfer system can further include a second conductive loop that is formed around the first conductive loop, and can also share the same type of symmetry as the first conductive loop. The wireless transfer system can be a wearable device or an implantable device.
FILED	Tuesday, May 15, 2018
APPL NO	15/979902
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/2804 (20130101) H01F 38/14 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/12 (20160201) Original (OR) Class Transmission H04B 5/0037 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/028 (20130101) H05K 1/165 (20130101) H05K 1/0284 (20130101) H05K 1/0393 (20130101) H05K 3/103 (20130101)
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10291247 — Chopping switch time-skew calibration in time-interleaved analog-to-digital converters

US 10291247	Verbruggen et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Xilinx, Inc. (San Jose, California)
ASSIGNEE(S)	XILINX, INC. (San Jose, California)
INVENTOR(S)	Bob W. Verbruggen (Saggart, Ireland); Christophe Erdmann (Dublin, Ireland); Bruno Miguel Vaz (Sao Domingos de Rana, Portugal)
ABSTRACT	An example time-skew calibration circuit includes a plurality of first circuits, each including a first accumulator and a second accumulator. The time-skew calibration circuit further includes a plurality of second circuits, each including a first adder coupled to outputs of the first accumulator and the second accumulator, and a first subtractor coupled to the outputs of the first accumulator and the second accumulator. The time-skew calibration circuit further includes a decision circuit configured to combine an output of the first adder and an output of the first subtractor.
FILED	Wednesday, March 07, 2018
APPL NO	15/914364
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Coding; Decoding; Code Conversion in General H03M 1/1023 (20130101) Original (OR) Class H03M 1/1028 (20130101) H03M 1/1215 (20130101)
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10291268 — Methods and systems for performing radio-frequency signal noise reduction in the absence of noise models

US 10291268	Migliori et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Benjamin J. Migliori (San Diego, California); Daniel J. Gebhardt (San Diego, California); Michael W. Walton (San Diego, California); Logan M. Straatemeier (San Diego, California)
ABSTRACT	Time-varying input signals are denoised by a neural network. The neural network learns features associated with noise added to reference signals. The neural network recognizes features of noisy time-varying input signals mixed with the noise that at least partially match at least some of the features associated with the noise. The neural network predicts denoised time-varying output signals that correspond to the time-varying input signals based on the recognized features of the noisy time-varying input signals that at least partially match at least some of the features associated with the noise.
FILED	Tuesday, July 25, 2017
APPL NO	15/659298
ART UNIT	2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) Transmission H04B 1/0475 (20130101) Original (OR) Class H04B 1/7176 (20130101) H04B 1/70712 (20130101) H04B 1/71055 (20130101)
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10291347 — Effective cross-layer satellite communications link interferences mitigation in the presence of various RFI types

US 10291347	Wang et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland)
ASSIGNEE(S)	INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland)
INVENTOR(S)	Gang Wang (Germantown, Maryland); Xin Tian (Germantown, Maryland); Zhihui Shu (Germantown, Maryland); Wenhao Xiong (Germantown, Maryland); Tien M. Nguyen (Yorba Linda, California); Khanh D. Pham (Kirtland AFB, New Mexico); Erik Blasch (Rome, New York); Dan Shen (Germantown, Maryland); Zhonghai Wang (Germantown, Maryland); Genshe Chen (Germantown, Maryland)
ABSTRACT	A systematic interferences mitigation design for protected satellite communications (SATCOM) is provided. An advanced channel coding is designed to provide coding gain for SATCOM even in the presence of synchronization errors because of unintentional and intentional radio frequency interferences (RFIs). A unified SATCOM system spectrum efficiency and energy efficiency performance model is developed with a unified interference model for SATCOM dynamic resource allocation (DRA). The SATCOM system DRA is designed with a game theoretic engine and link optimizations providing traffic control, power control, frequency hopping pattern selection, beamforming codebook selection, and modulation with coding agile waveform adaptations. The interferences mitigation design is implemented with software defined radio USRP and GNU-radio to maintain communication link quality of services (QoS).
FILED	Tuesday, January 03, 2017
APPL NO	15/397640
ART UNIT	2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Transmission H04B 1/0028 (20130101) H04B 1/715 (20130101) H04B 7/19 (20130101) H04B 17/345 (20150115) H04B 17/391 (20150115) H04B 2201/692 (20130101) H04B 2201/71323 (20130101) Secret Communication; Jamming of Communication H04K 3/25 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 27/0006 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 70/168 (20180101) Y02D 70/446 (20180101)
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10291633 — Bandwidth conserving signature deployment with signature set and network security

US 10291633	Harang et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Richard E Harang (Alexandria, Virginia); Lisa M Marvel (Churchville, Maryland); Travis W Parker (Abingdon, Maryland)
ABSTRACT	A malware detection system comprising a signature generator for combining malware signatures into a malware signature filter with a fixed false positive rate; a central location configured to send the malware signature filter to each of a plurality of hosts that are configured to scan files on the host system using the malware signature filter; each host configured such that if the scan indicates a positive result, the file is quarantined and the host sends identification back to central location if a false positive result is obtained for additional instruction. A method for malware detection operative to combine malware signatures into a filter with fixed false positive rate; comprising sending a malware signature filter to hosts for scanning of files on the host system and incoming data; if the malware signature filter returns a positive alert, identification is sent back to a central location.
FILED	Tuesday, October 18, 2016
APPL NO	15/330591
ART UNIT	2437 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 63/101 (20130101) H04L 63/1416 (20130101) Original (OR) Class H04L 63/1441 (20130101) H04L 67/10 (20130101) Wireless Communication Networks H04W 84/18 (20130101)
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10291645 — Determining maliciousness in computer networks

US 10291645	Frantzen et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Kudu Dynamics LLC (Chantilly, Virginia)
ASSIGNEE(S)	KUDU DYNAMICS LLC (Chantilly, Virginia)
INVENTOR(S)	Mike Frantzen (Catharpin, Virginia); Andrew Aarne Hendela (Annandale, Virginia); Bryan Hafen Leavitt (Westerville, Ohio)
ABSTRACT	A computer implemented method provides a technical solution to the technical problem of detecting and preventing malicious activity in a computer network, the technical solution involving calculating, based on hypergraph data, a maliciousness value indicating a likelihood of association of one or more nodes of the hypergraph with a known malicious actor, and programmatically performing, based on the calculated maliciousness value, one or more actions by a computer system designed to ensure security of the computer system.
FILED	Monday, July 09, 2018
APPL NO	16/029964
ART UNIT	2435 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/00 (20130101) G06F 21/55 (20130101) G06F 21/56 (20130101) G06F 21/552 (20130101) G06F 21/554 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/00 (20130101) H04L 63/14 (20130101) H04L 63/20 (20130101) H04L 63/145 (20130101) H04L 63/302 (20130101) H04L 63/1433 (20130101) Original (OR) Class H04L 63/1441 (20130101)
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Department of Energy (DOE)

10285945 — Formation of stable submicron peptide or protein particles by thin film freezing

US 10285945	Johnston et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Keith P. Johnston (Austin, Texas); Joshua Engstrom (Spotswood, New Jersey); Robert O. Williams, III (Austin, Texas)
ABSTRACT	The present invention includes compositions and methods for preparing micron-sized or submicron-sized particles by dissolving a water soluble effective ingredient in one or more solvents; spraying or dripping droplets solvent such that the effective ingredient is exposed to a vapor-liquid interface of less than 50, 100, 150, 200, 250, 200, 400 or 500 cm⁻¹area/volume to, e.g., increase protein stability; and contacting the droplet with a freezing surface that has a temperature differential of at least 30° C. between the droplet and the surface, wherein the surface freezes the droplet into a thin film with a thickness of less than 500 micrometers and a surface area to volume between 25 to 500 cm⁻¹.
FILED	Tuesday, April 04, 2017
APPL NO	15/479137
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1658 (20130101) A61K 9/1682 (20130101) Original (OR) Class Separation B01D 9/005 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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10286379 — Desiccant mixture compositions

US 10286379	Katsenovich
FUNDED BY	Department of Energy (DOE) Office of Environmental Management (DOE-EM)
APPLICANT(S)	Yelena Katsenovich (Miami, Florida)
ASSIGNEE(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S)	Yelena Katsenovich (Miami, Florida)
ABSTRACT	The invention pertains to desiccants within improved adsorption. The desiccants of the invention include silica, aluminum, bicarbonate and calcium. The addition of calcium increases the porosity of the resulting precipitated solid, which increases the adsorption properties. The invention also pertains to methods of preventing moisture damage to a chattel placed in an enclosed environment by placing the desiccant of the invention into the enclosed environment.
FILED	Monday, October 30, 2017
APPL NO	15/797786
ART UNIT	1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Separation B01D 53/261 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/043 (20130101) Original (OR) Class B01J 20/103 (20130101) B01J 20/0248 (20130101)
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10286383 — Mixed metal iron oxides and uses thereof

US 10286383	Shen et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	Research Triangle Institute (Research Triangle Park, North Carolina)
ASSIGNEE(S)	Research Triangle Institute (Research Triangle Park, North Carolina)
INVENTOR(S)	Jian-ping Shen (Chapel Hill, North Carolina); Marty Lail (Raleigh, North Carolina); Brian Turk (Durham, North Carolina); Paul D. Mobley (Raleigh, North Carolina); Jason S. Norman (Chapel Hill, North Carolina); Laura Douglas (Durham, North Carolina); Jonathan Peters (Durham, North Carolina)
ABSTRACT	This invention is directed to novel mixed transition metal iron (II/III) catalysts for the extraction of oxygen from CO₂and the selective reaction with organic compounds.
FILED	Thursday, November 09, 2017
APPL NO	15/808514
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/002 (20130101) B01J 23/74 (20130101) B01J 23/76 (20130101) B01J 23/78 (20130101) B01J 23/80 (20130101) B01J 23/83 (20130101) B01J 23/835 (20130101) Original (OR) Class B01J 23/8892 (20130101) B01J 23/8906 (20130101) B01J 35/002 (20130101) B01J 37/03 (20130101) B01J 37/14 (20130101) B01J 37/18 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/13 (20130101) B01J 2523/13 (20130101) B01J 2523/17 (20130101) B01J 2523/17 (20130101) B01J 2523/22 (20130101) B01J 2523/22 (20130101) B01J 2523/24 (20130101) B01J 2523/27 (20130101) B01J 2523/31 (20130101) B01J 2523/31 (20130101) B01J 2523/31 (20130101) B01J 2523/31 (20130101) B01J 2523/43 (20130101) B01J 2523/43 (20130101) B01J 2523/72 (20130101) B01J 2523/72 (20130101) B01J 2523/821 (20130101) B01J 2523/821 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/845 (20130101) B01J 2523/3706 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/40 (20130101) C01B 32/40 (20170801) C01B 2203/0238 (20130101) C01B 2203/1047 (20130101) C01B 2203/1064 (20130101) C01B 2203/1088 (20130101) C01B 2203/1235 (20130101) Acyclic or Carbocyclic Compounds C07C 2/84 (20130101) C07C 2/84 (20130101) C07C 5/42 (20130101) C07C 5/42 (20130101) C07C 5/42 (20130101) C07C 5/42 (20130101) C07C 5/42 (20130101) C07C 5/42 (20130101) C07C 5/42 (20130101) C07C 9/06 (20130101) C07C 9/06 (20130101) C07C 11/02 (20130101) C07C 11/02 (20130101) C07C 11/04 (20130101) C07C 11/04 (20130101) C07C 11/06 (20130101) C07C 11/06 (20130101) C07C 11/22 (20130101) C07C 11/22 (20130101) C07C 13/20 (20130101) C07C 13/20 (20130101) C07C 15/46 (20130101) C07C 15/46 (20130101) C07C 29/156 (20130101) C07C 29/156 (20130101) C07C 31/04 (20130101) C07C 31/04 (20130101) C07C 2521/04 (20130101) C07C 2521/06 (20130101) C07C 2521/08 (20130101) C07C 2523/46 (20130101) C07C 2523/74 (20130101) C07C 2523/78 (20130101) C07C 2523/80 (20130101) C07C 2523/83 (20130101) C07C 2523/89 (20130101) C07C 2523/835 (20130101) C07C 2523/889 (20130101) C07C 2601/16 (20170501) Heterocyclic Compounds C07D 301/03 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 27/00 (20130101) C10G 2400/22 (20130101) C10G 2400/30 (20130101) Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/463 (20130101) C10J 3/725 (20130101) C10J 2300/0969 (20130101) C10J 2300/0986 (20130101) C10J 2300/1653 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/18 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101)
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10286504 — Synthesis of paracetamol (acetaminophen) from biomass-derived p-hydroxybenzamide

US 10286504	Ralph et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	John Ralph (Madison, Wisconsin); Steven Karlen (Verona, Wisconsin); Justin Mobley (Cottage Grove, Wisconsin)
ABSTRACT	Disclosed is a method to make N-acetyl-p-aminophenol. The method includes steps for converting biomass-derived p-hydroxybenzoates to p-hydroxybenzamide, then to p-aminophenol; and then N-acetylating the p-aminophenol.
FILED	Wednesday, March 07, 2018
APPL NO	15/914597
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 19/04 (20130101) Original (OR) Class Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 3/02 (20130101) B60K 15/03006 (20130101) B60K 2015/03019 (20130101) B60K 2015/03026 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 11/1816 (20130101) B60L 11/1827 (20130101) B60L 11/1838 (20130101) B60L 11/1851 (20130101) B60L 11/1881 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/09 (20130101) Acyclic or Carbocyclic Compounds C07C 213/02 (20130101) C07C 231/10 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 23/1904 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/10 (20130101) H01M 8/04925 (20130101) H01M 16/006 (20130101) H01M 2220/20 (20130101) H01M 2250/20 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 90/12 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7005 (20130101) Y02T 90/32 (20130101)
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10286600 — Microporous membrane for stereolithography resin delivery

US 10286600	Deotte
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Joshua R. Deotte (Livermore, California)
ABSTRACT	A system for building a structure. The system includes a reservoir; an immiscible fluid in the reservoir; a membrane operatively connected to the reservoir; channels and delivery ports in the membrane; a microliter amount of curable resin; a delivery system for delivering the microliter amount of curable resin to channels and delivery ports in the membrane and to the reservoir in contact with the immiscible fluid in the reservoir; and an energy source adapted to deliver energy to the reservoir onto the microliter amount of curable resin for building the structure.
FILED	Wednesday, October 21, 2015
APPL NO	14/919408
ART UNIT	1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) B29C 64/124 (20170801) B29C 64/135 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 70/00 (20141201)
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10287223 — Systems and methods for separation and purification of products

US 10287223	Weiss et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	Calera Corporation (Moss Landing, California)
ASSIGNEE(S)	Calera Corporation (Moss Landing, California)
INVENTOR(S)	Michael Joseph Weiss (Los Gatos, California); Ryan J Gilliam (San Jose, California); Kyle Self (San Jose, California); Gal Mariansky (Morgan Hill, California); Margarete K Leclerc (Mountain View, California); Riyaz Mohammed Shipchandler (San Jose, California); Jacob Nagar (Durham, North Carolina)
ABSTRACT	There are provided methods and systems for an electrochemical cell including an anode and a cathode where the anode is contacted with a metal ion that converts the metal ion from a lower oxidation state to a higher oxidation state. The metal ion in the higher oxidation state is reacted with an unsaturated hydrocarbon and/or a saturated hydrocarbon to form products. Separation and/or purification of the products as well as of the metal ions in the lower oxidation state and the higher oxidation state, is provided herein.
FILED	Wednesday, October 25, 2017
APPL NO	15/793250
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 17/02 (20130101) Original (OR) Class C07C 17/02 (20130101) C07C 17/02 (20130101) C07C 19/01 (20130101) C07C 19/045 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 1/26 (20130101) C25B 1/46 (20130101) C25B 3/02 (20130101) C25B 9/08 (20130101)
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10287304 — Acid, solvent, and thermal resistant metal-organic frameworks

US 10287304	Yaghi et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Omar M. Yaghi (Berkeley, California); Seungkyu Lee (Oakland, California); Juncong Jiang (Berkeley, California); Yuebiao Zhang (Berkeley, California)
ABSTRACT	The disclosure provides for thermal, solvent, and/or acid resistant metal organic frameworks and the use of these frameworks in devices and methods for gas separation, gas storage, and catalysis. The disclosure further provides for MOFs that are strong solid acids, and the use of these strong solid acid MOFs in catalytic devices and catalytic methods.
FILED	Thursday, February 19, 2015
APPL NO	15/116186
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Separation B01D 33/00 (20130101) B01D 53/047 (20130101) B01D 53/228 (20130101) B01D 63/02 (20130101) B01D 2253/204 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) B01J 20/3085 (20130101) B01J 31/00 (20130101) B01J 31/1691 (20130101) B01J 37/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/003 (20130101) Original (OR) Class
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10287457 — Polishing slurry preventing agglomeration of charged colloids without loss of surface activity

US 10287457	Dylia-Spears et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Rebecca Dylia-Spears (Dublin, California); Michael Feit (Livermore, California); Phillip E. Miller (Livermore, California); William A. Steele (Tracy, California); Tayyab I. Suratwala (Pleasanton, California); Lana L. Wong (Pleasanton, California)
ABSTRACT	A method for chemically stabilizing polishing slurries in aqueous suspension to prevent their agglomeration while maintaining their surface activity is disclosed. The method prevents the formation of irreversible particle agglomerates during drying and permits the subsequent re-suspension of dried particles with no impact on the particle size distribution. The stabilization method can be customized based on knowledge of the colloid surface charge at suspension pH conditions, addition of a charged species having like charge to the colloid at the suspension conditions, and control of the concentrations of the charged species and other ions in suspension.
FILED	Wednesday, October 16, 2013
APPL NO	14/437453
ART UNIT	1716 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Machines, Devices, or Processes for Grinding or Polishing; Dressing or Conditioning of Abrading Surfaces; Feeding of Grinding, Polishing, or Lapping Agents B24B 37/04 (20130101) B24B 37/044 (20130101) Polishing Compositions; Ski Waxes C09G 1/02 (20130101) C09G 1/04 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/1436 (20130101) C09K 3/1463 (20130101)
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10287526 — Method to produce catalytically active nanocomposite coatings

US 10287526	Erdemir et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S)	UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Ali Erdemir (Naperville, Illinois); Osman Levent Eryilmaz (Plainfield, Illinois); Mustafa Urgen (Istanbul, Turkey); Kursat Kazmanli (Istanbul, Turkey)
ABSTRACT	A nanocomposite coating and method of making and using the coating. The nanocomposite coating is disposed on a base material, such as a metal or ceramic; and the nanocomposite consists essentially of a matrix of an alloy selected from the group of Cu, Ni, Pd, Pt and Re which are catalytically active for cracking of carbon bonds in oils and greases and a grain structure selected from the group of borides, carbides and nitrides.
FILED	Monday, December 18, 2017
APPL NO	15/845936
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 27/22 (20130101) B01J 27/24 (20130101) B01J 35/002 (20130101) B01J 37/0225 (20130101) B01J 37/347 (20130101) B01J 37/349 (20130101) Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 103/04 (20130101) C10M 125/02 (20130101) C10M 169/04 (20130101) Original (OR) Class C10M 2201/05 (20130101) C10M 2201/061 (20130101) C10M 2201/087 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2210/01 (20130101) C10N 2210/02 (20130101) C10N 2210/03 (20130101)
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10287566 — DHAD variants and methods of screening

US 10287566	Kelly et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Butamax Advanced Biofuels LLC (Wilmington, Delaware)
ASSIGNEE(S)	Butamax Advanced Biofuels LLC (Wilmington, Delaware)
INVENTOR(S)	Kristen J. Kelly (Wilmington, Delaware); Rick W. Ye (Hockessin, Delaware)
ABSTRACT	Methods of screening for dihydroxy-acid dehydratase (DHAD) variants that display increased DHAD activity are disclosed, along with DHAD variants identified by these methods. Such enzymes can result in increased production of compounds from DHAD requiring biosynthetic pathways. Also disclosed are isolated nucleic acids encoding the DHAD variants, recombinant host cells comprising the isolated nucleic acid molecules, and methods of producing butanol.
FILED	Monday, January 16, 2017
APPL NO	15/406876
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Separation B01D 11/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Original (OR) Class C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/16 (20130101) C12P 7/40 (20130101) Enzymes C12Y 101/01001 (20130101) C12Y 101/01086 (20130101) C12Y 202/01006 (20130101) C12Y 402/01009 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101)
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10287575 — Methods for generating barcoded combinatorial libraries

US 10287575	Gill et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	The Regents of the University of Colorado (Denver, Colorado); Inscripta, Inc. (Boulder, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado, a body corporate (Denver, Colorado); Inscripta, Inc. (Boulder, Colorado)
INVENTOR(S)	Ryan T. Gill (Denver, Colorado); Andrew Garst (Boulder, Colorado); Tanya Elizabeth Warnecke Lipscomb (Boulder, Colorado); Marcelo Colika Bassalo (Boulder, Colorado); Ramsey Ibrahim Zeitoun (San Francisco, California)
ABSTRACT	Provided herein are methods and composition for trackable genetic variant libraries. Further provided herein are methods and compositions for recursive engineering. Further provided herein are methods and compositions for multiplex engineering. Further provided herein are methods and compositions for enriching for editing and trackable engineered sequences and cells using nucleic acid-guided nucleases.
FILED	Monday, April 09, 2018
APPL NO	15/948798
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/102 (20130101) C12N 15/102 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 15/1079 (20130101) C12N 15/1082 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2563/179 (20130101)
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10287611 — Engineering the pathway for succinate production

US 10287611	Zhang et al.
FUNDED BY	Department of Energy (DOE) Department of Agriculture (USDA)
APPLICANT(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S)	Xueli Zhang (Tianjin, China PRC); Kaemwich Jantama (Chiang Mai, Thailand); Jonathan C. Moore (Encinitas, California); Laura R. Jarboe (Ames, Iowa); Keelnatham T. Shanmugam (Gainesville, Florida); Lonnie O'Neal Ingram (Gainesville, Florida)
ABSTRACT	This invention relates to biocatalysts for the efficient production of succinic acid and/or other products from renewable biological feedstocks. The biocatalysts have a very high efficiency for the growth-coupled production of succinic acid and/or other products from carbohydrate feed stocks as a result of both genetic manipulation and metabolic evolution. More specifically, certain biocatalysts of the present invention produce succinic acid at high titers and yields in mineral salts media during simple pH-controlled batch fermentation without the addition of any exogenous genetic material. The genetic manipulations of the present invention are concerned with energy-conserving strategies coupled with the elimination of alternative routes for NADH oxidation other than the routes for succinic acid production. The biocatalysts contain glucose-repressed gluconeogenic phosphoenolpyruvate carboxykinase (pck) derepressed by genetic modifications and a genetically-inactivated phosphotransferase system. In terms of succinic acid production efficiency, the biocatalysts of the present invention are functionally equivalent to succinate producing rumen bacteria such as Actinobacillus succinogens and Mannheimia succiniproducens, with one difference: that the biocatalysts are able to achieve this high level of succinic acid production in a minimal salt medium with carbohydrate source, as opposed to the requirement for a rich medium for succinic acid production by rumen bacteria.
FILED	Wednesday, May 06, 2015
APPL NO	14/705011
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 9/93 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/46 (20130101) Original (OR) Class Enzymes C12Y 401/01 (20130101) C12Y 604/01001 (20130101)
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10287627 — Multiplexed linking PCR

US 10287627	Gill et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF COLORADO, a body corporate (Denver, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S)	Ryan T. Gill (Denver, Colorado); Ramsey Zeitoun (Boulder, Colorado); Andrew Garst (Boulder, Colorado)
ABSTRACT	The invention provides compositions and methods for rapid assembly of one or more assembled polynucleotides from a plurality of component polynucleotides, as well as methods of designing polynucleotide primer and linker sets useful in the assembly methods of the invention.
FILED	Monday, February 09, 2015
APPL NO	15/116300
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6853 (20130101) Original (OR) Class C12Q 1/6853 (20130101) C12Q 2525/155 (20130101) C12Q 2525/161 (20130101) C12Q 2537/101 (20130101) C12Q 2537/143 (20130101) Enzymes C12Y 207/07007 (20130101)
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10287693 — Electrochemical systems and methods

US 10287693	Gilliam et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	Calera Corporation (Moss Landing, California)
ASSIGNEE(S)	Calera Corporation (Moss Landing, California)
INVENTOR(S)	Ryan J Gilliam (San Jose, California); Michael Kostowskyj (Los Gatos, California); Thomas H McWaid (Santa Cruz, California); Samaresh Mohanta (Dublin, California); Hong Zhao (Marina, California)
ABSTRACT	Disclosed herein are ion exchange membranes, electrochemical systems, and methods that relate to various configurations of the ion exchange membranes and other components of the electrochemical cell.
FILED	Tuesday, November 20, 2018
APPL NO	16/196199
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/00 (20130101) Original (OR) Class C25B 9/08 (20130101) C25B 9/063 (20130101) C25B 13/02 (20130101) C25B 13/04 (20130101)
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10287701 — Nanoparticle deposition in porous and on planar substrates

US 10287701	Pal et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	The Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S)	The Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S)	Uday B. Pal (Dover, Massachusetts); Soumendra Basu (Westwood, Massachusetts); Paul Gasper (Watertown, Massachusetts); Yanchen Lu (Boston, Massachusetts); Srikanth Gopalan (Westborough, Massachusetts)
ABSTRACT	A method of preparing a metal nanoparticle on a surface includes subjecting a metal source to a temperature and a pressure in a carrier gas selected to provide a vapor metal species at a vapor pressure in the range of about 10⁻⁴to about 10⁻¹¹atm; contacting the vapor metal species with a heated substrate; and depositing the metal as a nanoparticle on the substrate.
FILED	Wednesday, July 19, 2017
APPL NO	15/654152
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/02 (20130101) C23C 14/18 (20130101) C23C 14/0021 (20130101) C23C 14/046 (20130101) C23C 14/083 (20130101) C23C 14/228 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 7/006 (20130101) C25D 17/10 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/00 (20130101)
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10287894 — Turbine component and methods of making and cooling a turbine component

US 10287894	Dutta et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
ASSIGNEE(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S)	Sandip Dutta (Greenville, South Carolina); James Zhang (Greenville, South Carolina); Gary Michael Itzel (Simpsonville, South Carolina); John McConnell Delvaux (Fountain Inn, South Carolina); Matthew Troy Hafner (Honea Path, South Carolina)
ABSTRACT	A turbine component includes a root and an airfoil extending from the root to a tip opposite the root. The airfoil forms a leading edge and a trailing edge portion extending to a trailing edge. A plurality of nested cooling channels in the trailing edge portion of the airfoil permit passage of a cooling fluid from an interior of the turbine component to an exterior of the turbine component at the trailing edge portion. A method of making a turbine component includes forming an airfoil having a leading edge, a trailing edge portion extending to a trailing edge, and a plurality of nested cooling channels in the trailing edge portion. Each nested cooling channel fluidly connects an interior of the turbine component with an exterior of the turbine component at the trailing edge portion. A method of cooling a turbine component is also disclosed.
FILED	Monday, June 06, 2016
APPL NO	15/174182
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/24 (20130101) B22F 3/1055 (20130101) B22F 2998/10 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 15/0086 (20130101) B23K 15/0093 (20130101) B23K 26/0006 (20130101) B23K 26/70 (20151001) B23K 26/342 (20151001) B23K 2101/001 (20180801) B23K 2103/08 (20180801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 28/042 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) F01D 5/187 (20130101) Original (OR) Class F01D 5/282 (20130101) F01D 9/02 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/30 (20130101) F05D 2230/22 (20130101) F05D 2230/30 (20130101) F05D 2240/122 (20130101) F05D 2240/304 (20130101) F05D 2250/183 (20130101) F05D 2250/184 (20130101) F05D 2250/185 (20130101) F05D 2260/20 (20130101) F05D 2260/204 (20130101) F05D 2300/175 (20130101) F05D 2300/6033 (20130101)
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10288121 — Rotation flexure with temperature controlled modal frequency

US 10288121	Salas et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Theodore E. Salas (Los Lunas, New Mexico); Patrick S. Barney (Albuquerque, New Mexico); Aaron M. Ison (Albuquerque, New Mexico); Ronald L. Akau (Albuquerque, New Mexico); Nathan Weir (Albuquerque, New Mexico)
ABSTRACT	A flexure bearing includes an inner race, an outer race, and a plurality of substantially planar radially extending blades coupled between the inner and outer race. The blades have a thickness that is thinner than a thickness of the inner and outer races. The inner race, outer race, and blades have substantially the same height. At least one heating element is coupled to the inner race and/or the outer race. The heating element is configured to apply heat to the race that it is coupled to in order to tune the flexure bearing.
FILED	Wednesday, August 02, 2017
APPL NO	15/667524
ART UNIT	3656 — Material and Article Handling
CURRENT CPC	Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 11/12 (20130101) F16C 17/22 (20130101) F16C 17/243 (20130101) F16C 19/522 (20130101) F16C 19/525 (20130101) F16C 19/527 (20130101) F16C 27/04 (20130101) F16C 37/007 (20130101) F16C 41/00 (20130101) Original (OR) Class F16C 2202/20 (20130101) F16C 2370/20 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 1/185 (20130101) F16F 2238/022 (20130101)
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10288290 — Device for improved air and fuel distribution to a combustor

US 10288290	Laster et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Siemens Energy, Inc. (Orlando, Florida)
ASSIGNEE(S)	SIEMENS ENERGY, INC. (Orlando, Florida)
INVENTOR(S)	Walter Ray Laster (Oviedo, Florida); Reinhard Schilp (Winter Park, Florida)
ABSTRACT	A flow conditioning device for a can annular gas turbine engine, including a plurality of flow elements disposed in a compressed air flow path leading to a combustor, configured such that relative adjustment of at least one flow directing element with respect to an adjacent flow directing element during operation of the gas turbine engine is effective to adjust a level of choking of the compressed air flow path.
FILED	Wednesday, April 27, 2016
APPL NO	15/139970
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/141 (20130101) F01D 17/162 (20130101) F01D 17/165 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/20 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/10 (20130101) Original (OR) Class F23R 3/14 (20130101) F23R 3/26 (20130101)
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10288482 — Extended cavity laser absorption spectroscopy

US 10288482	Smith
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Mark W. Smith (Albuquerque, New Mexico)
ABSTRACT	Technologies for detecting absorption of electromagnetic radiation traveling through a measurement volume of interest are described herein. In a general embodiment, a laser is used to emit electromagnetic radiation through the measurement volume where absorption is desirably detected. An optical collector receives a portion of the radiation and directs a first fraction of the portion back to a gain medium of the laser, where the radiation is amplified and emitted again, and directs a second fraction to an optical sensor that can detect absorption in the measurement volume based upon attenuation of energy of the radiation. As the radiation feeds back to the gain medium and is emitted again, energy at attenuated wavelengths is amplified less than at other wavelengths. Thus, attenuation of energy of the radiation due to absorption in the measurement volume is cumulative, and relatively small absorptions are amplified, allowing smaller absorptions to be detected more easily.
FILED	Wednesday, February 03, 2016
APPL NO	15/014852
ART UNIT	2877 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/12 (20130101) G01J 3/42 (20130101) Original (OR) Class G01J 3/0208 (20130101) G01J 3/0216 (20130101) G01J 3/0264 (20130101)
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10288729 — Apodization of spurs in radar receivers using multi-channel processing

US 10288729	Doerry et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Armin W. Doerry (Albuquerque, New Mexico); Douglas L. Bickel (Albuquerque, New Mexico)
ABSTRACT	The various technologies presented herein relate to identification and mitigation of spurious energies or signals (aka “spurs”) in radar imaging. Spurious energy in received radar data can be a consequence of non-ideal component and circuit behavior. Such behavior can result from I/Q imbalance, nonlinear component behavior, additive interference (e.g. cross-talk, etc.), etc. The manifestation of the spurious energy in a radar image (e.g., a range-Doppler map) can be influenced by appropriate pulse-to-pulse phase modulation. Comparing multiple images which have been processed using the same data but of different signal paths and modulations enables identification of undesired spurs, with subsequent cropping or apodization of the undesired spurs from a radar image. Spurs can be identified by comparison with a threshold energy. Removal of an undesired spur enables enhanced identification of true targets in a radar image.
FILED	Wednesday, October 18, 2017
APPL NO	15/786935
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/292 (20130101) G01S 7/414 (20130101) G01S 13/9035 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 2207/20212 (20130101)
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10289143 — Agent-based microgrid architecture for generation following protocols

US 10289143	Goldsmith
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Steven Goldsmith (Rochester, Minnesota)
ASSIGNEE(S)	Michigan Technological University (Houghton, Michigan)
INVENTOR(S)	Steven Goldsmith (Rochester, Minnesota)
ABSTRACT	A system for predicting power and loads over a single, relatively short time horizon. More specifically, a system comprising a Storage Agent (S-agent) Cohort within a grid control society, wherein the system expands G and L intra-cohort protocols to allow the S-cohort to participate in power management of the grid by scheduling storage components in source or load roles as determined by the time-varying state of the power imbalance and by the risk-adjusting capacity margin relationship between the G and L cohorts.
FILED	Friday, June 12, 2015
APPL NO	15/318069
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Systems for Regulating Electric or Magnetic Variables G05F 1/66 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/06 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/00 (20130101) H02J 3/382 (20130101) H02J 3/383 (20130101) H02J 3/386 (20130101) H02J 5/00 (20130101) H02J 7/34 (20130101) H02J 7/35 (20130101) H02J 7/0052 (20130101) H02J 7/345 (20130101) H02J 13/00 (20130101) H02J 2003/007 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/04 (20130101) H02M 7/44 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/563 (20130101) Y02E 10/566 (20130101) Y02E 10/763 (20130101)
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10289329 — Burst buffer dynamic logical volume sizing in high performance computing environment

US 10289329	Gooding et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Thomas M. Gooding (Rochester, Minnesota); David L. Hermsmeier (Oronoco, Minnesota); Jin Ma (Ontario, Canada); Gary J. Mincher (Poughkeepsie, New York); Bryan S. Rosenburg (Cortlandt Manor, New York)
ABSTRACT	A method, data processing system and program product utilize dynamic logical storage volume sizing for burst buffers or other local storage for computing nodes to optimize job stage in, execution and/or stage out.
FILED	Wednesday, February 15, 2017
APPL NO	15/433998
ART UNIT	2136 — Memory Access and Control
CURRENT CPC	Electric Digital Data Processing G06F 3/067 (20130101) G06F 3/0605 (20130101) G06F 3/0631 (20130101) Original (OR) Class G06F 11/1407 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/1097 (20130101)
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10289573 — Bus based timed input output module

US 10289573	Boyd et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Gerald M. Boyd (Albuquerque, New Mexico); Dominic A. Montoya (Albuquerque, New Mexico); Gregory L. Wickstrom (Albuquerqe, New Mexico); Jeffrey E. Farrow (Albuquerque, New Mexico)
ABSTRACT	Described herein are features related to a bus based timed input output module (TIO) for use in control systems of physical systems, particularly where the physical systems are safety critical systems. When the TIO is powered on, one or more operations are performed by the TIO, wherein the one or more operations, when performed by the TIO: 1) cause the TIO to be non-functional, thereby preventing the TIO from improperly or accidentally activating a Component in communication with the TIO; 2) clears the TIO of previous operations (if any); and 3) facilitates compatibility of the TIO with an arbitrary Component.
FILED	Wednesday, September 06, 2017
APPL NO	15/696417
ART UNIT	2185 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 13/122 (20130101) Original (OR) Class G06F 13/3625 (20130101)
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10290063 — System and method for instantaneous power decomposition and estimation

US 10290063	Yang et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) Office of Fossil Energy and Carbon Management (FECM) National Energy Technology Laboratory (NETL)
APPLICANT(S)	EATON CORPORATION (Cleveland, Ohio)
ASSIGNEE(S)	UNITED STATES DEPARTMENT OF ENERGY (Washington, District of Columbia)
INVENTOR(S)	Yi Yang (Milwaukee, Wisconsin); Liang Du (Atlanta, Georgia); Dawei He (Beijing, China PRC)
ABSTRACT	A system disaggregates and estimates power consumption of electric loads powered by a single electrical outlet. The system includes a processor having a routine; a current sensor cooperating with the processor to measure samples for one line cycle of an aggregated current waveform for the electric loads powered by the single electrical outlet; and a voltage sensor cooperating with the processor to measure samples for the one line cycle of a voltage waveform for the electric loads powered by the single electrical outlet. The processor routine transfers the measured samples for the one line cycle of the aggregated current waveform and the voltage waveform into an aggregated voltage-current trajectory for the single electrical outlet, and provides an instantaneous decomposition of power consumption for a plurality of different categories of the electric loads from the aggregated voltage-current trajectory for the one line cycle.
FILED	Tuesday, June 18, 2013
APPL NO	13/920602
ART UNIT	2864 — Printing/Measuring and Testing
CURRENT CPC	Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 4/00 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/06 (20130101) Original (OR) Class Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 20/38 (20130101)
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10290195 — System and method of detecting and analyzing a threat in a confined environment

US 10290195	Skorpik et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	James R. Skorpik (Kennewick, Washington); Michael S. Hughes (Richland, Washington); Eric G. Gonzalez (Richland, Washington)
ABSTRACT	A system and method of detecting and analyzing a threat in a confined environment is disclosed. An audio board detects and analyzes audio signals which are then transmitted and analyzed to determine the location of a gunshot in a confined location and the type of firearm being shot.
FILED	Thursday, February 23, 2017
APPL NO	15/440902
ART UNIT	2686 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/18 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 7/064 (20130101) G08B 13/1672 (20130101) G08B 21/02 (20130101) Original (OR) Class G08B 25/009 (20130101) G08B 29/185 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/51 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 3/005 (20130101) H04R 2499/11 (20130101)
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10290480 — Methods of resolving artifacts in Hadamard-transformed data

US 10290480	Crowell et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Kevin Crowell (Richland, Washington); Spencer A. Prost (Tempe, Arizona)
ABSTRACT	Apparatus and methods are disclosed for processing data transformed according to an invertible transform (e.g., using a Hadamard transform) multiplexing scheme. In one example of the disclosed technology, a computer-implemented method includes generating transformed data by applying a Hadamard transform to intensity data generated by modulating input of analytes into a mass spectrometer according to a pseudorandom sequence (PRS). The exemplary method further includes identifying at least one pair of symmetric intensity peaks in the transformed data based on the PRS and removing data associated with the pair of symmetric peaks from the transformed data to produce modified data, which can be used to identify, characterize, and/or quantify the composition of the sample. In some examples, the exemplary method further includes validating peaks in the transformed data based on comparing the location of peaks in the untransformed intensity data.
FILED	Friday, April 19, 2013
APPL NO	13/866686
ART UNIT	2853 — Printing/Measuring and Testing
CURRENT CPC	Electric Digital Data Processing G06F 19/703 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0036 (20130101) Original (OR) Class
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10290507 — Formation of antireflective surfaces

US 10290507	Black et al.
FUNDED BY	Department of Energy (DOE) Brookhaven Science Associates, LLC (BSA) Office of Science (DOE-SC) Brookhaven National Laboratory (BNL) Federally Funded Research and Development Center (FFRDC) Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S)	Brookhaven Science Associates, LLC (Upton, New York)
ASSIGNEE(S)	BROOKHAVEN SCIENCE ASSOCIATES, LLC (Upton, New York)
INVENTOR(S)	Charles T. Black (New York, New York); Atikur Rahman (Ridge, New York); Matthew Eisaman (Port Jefferson, New York); Ahsan Ashraf (Port Jefferson, New York)
ABSTRACT	Technologies are described for methods and systems effective for etching nanostructures in a substrate. The methods may comprise depositing a patterned block copolymer on the substrate. The patterned block copolymer may include first and second polymer block domains. The methods may comprise applying a precursor to the patterned block copolymer to generate an infiltrated block copolymer. The precursor may infiltrate into the first polymer block domain and generate a material in the first polymer block domain. The methods may comprise applying a removal agent to the infiltrated block copolymer to generate a patterned material. The removal agent may be effective to remove the first and second polymer block domains from the substrate. The methods may comprise etching the substrate. The patterned material on the substrate may mask the substrate to pattern the etching. The etching may be performed under conditions to produce nanostructures in the substrate.
FILED	Friday, June 13, 2014
APPL NO	14/897481
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/0149 (20130101) Optical Elements, Systems, or Apparatus G02B 1/118 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) G03F 7/405 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 2237/334 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0271 (20130101) H01L 21/0273 (20130101) H01L 21/0337 (20130101) H01L 21/3065 (20130101) H01L 21/3086 (20130101) Original (OR) Class
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10290732 — High voltage semiconductor devices and methods of making the devices

US 10290732	Matocha et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Monolith Semiconductor Inc. (Round Rock, Texas)
ASSIGNEE(S)	Monolith Semiconductor Inc. (Round Rock, Texas)
INVENTOR(S)	Kevin Matocha (Round Rock, Texas); Kiran Chatty (Round Rock, Texas); Sujit Banerjee (Round Rock, Texas)
ABSTRACT	A multi-cell MOSFET device including a MOSFET cell with an integrated Schottky diode is provided. The MOSFET includes n-type source regions formed in p-type well regions which are formed in an n-type drift layer. A p-type body contact region is formed on the periphery of the MOSFET. The source metallization of the device forms a Schottky contact with an n-type semiconductor region adjacent the p-type body contact region of the device. Vias can be formed through a dielectric material covering the source ohmic contacts and/or Schottky region of the device and the source metallization can be formed in the vias. The n-type semiconductor region forming the Schottky contact and/or the n-type source regions can be a single continuous region or a plurality of discontinuous regions alternating with discontinuous p-type body contact regions. The device can be a SiC device. Methods of making the device are also provided.
FILED	Monday, December 18, 2017
APPL NO	15/844766
ART UNIT	2893 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/046 (20130101) H01L 21/0485 (20130101) H01L 21/0495 (20130101) H01L 21/8213 (20130101) H01L 21/823412 (20130101) H01L 27/0629 (20130101) H01L 27/0727 (20130101) H01L 29/0619 (20130101) H01L 29/0696 (20130101) H01L 29/872 (20130101) H01L 29/1095 (20130101) H01L 29/1608 (20130101) H01L 29/7806 (20130101) Original (OR) Class H01L 29/66068 (20130101)
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10290753 — Mid-infrared photodetectors

US 10290753	Guyot-Sionnest et al.
FUNDED BY	Department of Energy (DOE) National Science Foundation (NSF)
APPLICANT(S)	The University of Chicago (Chicago, Illinois)
ASSIGNEE(S)	The University of Chicago (Chicago, Illinois)
INVENTOR(S)	Philippe Guyot-Sionnest (Chicago, Illinois); Sean E. Keuleyan (Chicago, Illinois); Emmanuel Lhuillier (Chicago, Illinois)
ABSTRACT	Nanoparticles, methods of manufacture, devices comprising the nanoparticles, methods of their manufacture, and methods of their use are provided herein. The nanoparticles and devices having photoabsorptions in the range of 1.7 μm to 12 μm and can be used as photoconductors, photodiodes, phototransistors, charge-coupled devices (CCD), luminescent probes, lasers, thermal imagers, night-vision systems, and/or photodetectors.
FILED	Monday, March 07, 2016
APPL NO	15/062418
ART UNIT	2884 — Optics
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/89 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/4228 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/146 (20130101) H01L 31/09 (20130101) H01L 31/0272 (20130101) H01L 31/0296 (20130101) Original (OR) Class H01L 31/0324 (20130101) H01L 31/1828 (20130101) H01L 31/035218 (20130101)
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10290816 — Organic electroluminescent materials and devices

US 10290816	Forrest et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Stephen R. Forrest (Ann Arbor, Michigan); Jaesang Lee (Ann Arbor, Michigan); Quinn Burlingame (Ann Arbor, Michigan)
ABSTRACT	An organic light emitting device is disclosed whose emissive layer has a host material, a first emissive dopant, and a second dopant. The second dopant is an excited energy state managing dopant provided in an amount between 2-10 vol. % of the emissive layer and has a lowest triplet state energy level, T_M, that is higher than a lowest triplet state energy levels, T₁, of both the host and the first dopant and lower than the multiply-excited energy level, T*, of the first dopant.
FILED	Wednesday, November 09, 2016
APPL NO	15/347371
ART UNIT	2814 — Semiconductors/Memory
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/185 (20130101) C09K 2211/1007 (20130101) C09K 2211/1014 (20130101) C09K 2211/1029 (20130101) C09K 2211/1044 (20130101) C09K 2211/1092 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0061 (20130101) H01L 51/0072 (20130101) Original (OR) Class H01L 51/0074 (20130101) H01L 51/0085 (20130101) H01L 51/0087 (20130101) H01L 51/5004 (20130101) H01L 51/5016 (20130101) H01L 51/5024 (20130101) H01L 51/5028 (20130101) H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 51/5096 (20130101)
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10290868 — Cathodes for rechargeable lithium-ion batteries

US 10290868	Goodenough et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	John B. Goodenough (Austin, Texas); Kyu-Sung Park (Suwon, South Korea); Steen Schougaard (Glostrup, Denmark)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	John B. Goodenough (Austin, Texas); Kyu-Sung Park (Suwon, South Korea); Steen Schougaard (Glostrup, Denmark)
ABSTRACT	The present invention includes an apparatus and method of making and using a composition that includes the replacement of electrochemically inactive additives with a conductive and electrochemically active polymer that is attached so as to make an electrical contract to the redox couples of the electrochemically active oxide particles into/from which Lithium is reversibly inserted/extracted in a battery discharge/charge cycle.
FILED	Thursday, June 01, 2006
APPL NO	11/447510
ART UNIT	1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/60 (20130101) H01M 4/131 (20130101) H01M 4/136 (20130101) H01M 4/137 (20130101) H01M 4/364 (20130101) H01M 4/366 (20130101) H01M 4/485 (20130101) Original (OR) Class H01M 4/505 (20130101) H01M 4/608 (20130101) H01M 4/5825 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101)
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10290871 — Battery cell engineering and design to reach high energy

US 10290871	Masarapu et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) U.S. State Government State of California California Energy Commission (CEC)
APPLICANT(S)	Envia Systems, Inc. (Newark, California)
ASSIGNEE(S)	Zenlabs Energy, Inc. (Fremont, California)
INVENTOR(S)	Charan Masarapu (Fremont, California); Haixia Deng (Fremont, California); Yongbong Han (San Francisco, California); Yogesh Kumar Anguchamy (Newark, California); Subramanian Venkatachalam (Pleasanton, California); Sujeet Kumar (Newark, California); Herman A. Lopez (Sunnyvale, California)
ABSTRACT	Improved high energy capacity designs for lithium ion batteries are described that take advantage of the properties of high specific capacity anode active compositions and high specific capacity cathode active compositions. In particular, specific electrode designs provide for achieving very high energy densities. Furthermore, the complex behavior of the active materials is used advantageously in a radical electrode balancing design that significantly reduced wasted electrode capacity in either electrode when cycling under realistic conditions of moderate to high discharge rates and/or over a reduced depth of discharge.
FILED	Wednesday, June 24, 2015
APPL NO	14/749099
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/024 (20130101) H01M 2/1646 (20130101) H01M 4/38 (20130101) H01M 4/131 (20130101) H01M 4/134 (20130101) H01M 4/386 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/582 (20130101) Original (OR) Class H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 10/446 (20130101) H01M 10/0525 (20130101) H01M 2220/20 (20130101)
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10290890 — Poly(aryl piperidinium) polymers for use as hydroxide exchange membranes and ionomers

US 10290890	Yan et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	University of Delaware (Newark, Delaware)
ASSIGNEE(S)	Universty of Delaware (Newark, Delaware)
INVENTOR(S)	Yushan Yan (Hockessin, Delaware); Bingjun Xu (West Chester, Pennsylvania); Junhua Wang (Newark, Delaware); Yun Zhao (Newark, Delaware)
ABSTRACT	Poly(aryl piperidinium) polymers are provided which have an alkaline-stable cation, piperidinium, introduced into a rigid aromatic polymer backbone free of ether bonds. Hydroxide exchange membranes or hydroxide exchange ionomers formed from these polymers exhibit superior chemical stability, hydroxide conductivity, decreased water uptake, good solubility in selected solvents, and improved mechanical properties in an ambient dry state as compared to conventional hydroxide exchange membranes or ionomers. Hydroxide exchange membrane fuel cells comprising the poly(aryl piperidinium) polymers exhibit enhanced performance and durability at relatively high temperatures.
FILED	Friday, September 28, 2018
APPL NO	16/146887
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Separation B01D 71/44 (20130101) B01D 71/62 (20130101) B01D 71/82 (20130101) B01D 2325/42 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 10/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2262 (20130101) C08J 2361/18 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/106 (20130101) H01M 8/1023 (20130101) Original (OR) Class H01M 8/1039 (20130101) H01M 8/1069 (20130101) H01M 8/1081 (20130101) H01M 2008/1095 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/56 (20151101)
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10290950 — Dual-band GPS antenna with horizontal polarization

US 10290950	Crocker et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Dylan Andrew Crocker (Albuquerque, New Mexico); Bernd H. Strassner, II (Albuquerque, New Mexico); Troy Satterthwait (Rio Rancho, New Mexico)
ABSTRACT	An antenna array is described herein that is suitable for dual-band GPS reception. The antenna array includes a plurality of dipole antennas arranged in a circular pattern. The antenna array further includes a feed network, separated from the dipole antennas by an insulating plate, and that passes electrical signals output by the dipole antennas to a feed line. The feed network comprises a central plate in contact with the feed line, and a plurality of arms aligned with the dipoles and extending from the center plate toward the outer edges of the circular pattern. The arms cross over slots in each of the dipole antennas. Electromagnetic waves that impinge on the dipoles induce signals that travel down the slots in the dipoles and couple to the arms of the feed network where the arms cross over the slots. The signals then travel along the feed network to the feed line.
FILED	Wednesday, August 23, 2017
APPL NO	15/684560
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/24 (20130101) H01Q 21/0006 (20130101) H01Q 21/062 (20130101) Original (OR) Class
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10290996 — Bottom emitting vertical-cavity surface-emitting lasers

US 10290996	Mathai et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Palo Alto, California)
ASSIGNEE(S)	Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S)	Sagi Varghese Mathai (Sunnyvale, California); Stanley Cheung (Palo Alto, California); Wayne V. Sorin (Mountain View, California); Michael Renne Ty Tan (Menlo Park, California)
ABSTRACT	A bottom-emitting vertical-cavity surface-emitting laser (VCSEL) structure includes a first substrate permitting the passage of light therethrough, an n-doped distributed Bragg reflector (nDBR), a p-doped distributed Bragg reflector (pDBR), one or more active layers, at least one of a high contrast grating mirror and a dielectric-enhanced metal mirror, and a plurality of layers, where the VCSEL structure is configured to be flip chipped to a second substrate. The pDBR and the nDBR define a laser cavity extending vertically therebetween and containing the one or more active layers. The at least one of a high contrast grating mirror and a dielectric-enhanced metal mirror may be disposed over the pDBR. The plurality of layers may be disposed over the at least one of the high contrast grating mirror and the dielectric-enhanced metal mirror to optically and hermetically seal the laser cavity.
FILED	Wednesday, April 25, 2018
APPL NO	15/962649
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/183 (20130101) H01S 5/187 (20130101) H01S 5/0224 (20130101) H01S 5/02476 (20130101) H01S 5/18305 (20130101) Original (OR) Class H01S 5/18308 (20130101) H01S 5/18311 (20130101) H01S 5/18369 (20130101) H01S 5/18375 (20130101) H01S 5/18388 (20130101)
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10291025 — Systems and methods for improved stability of power systems

US 10291025	Baone et al.
FUNDED BY	Department of Energy (DOE) Office of Electricity (DOE-OE)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S)	Chaitanya Ashok Baone (Glenville, New York); Naresh Acharya (Schenectady, New York); Nilanjan Ray Chaudhuri (Fargo, North Dakota)
ABSTRACT	The embodiments described herein provide for a system including a processor. The processor is configured to select at least one grid system contingency from a plurality of grid system contingencies. The processor is further configured to derive one or more eigen-sensitivity values based on the at least on grid system contingency. The processor is also configured to derive one or more control actions at least partially based on the eigen-sensitivity values. The processor is additionally configured to apply the one or more control actions for generation re-dispatch of a grid system.
FILED	Wednesday, April 22, 2015
APPL NO	14/693590
ART UNIT	2117 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/10 (20130101) Original (OR) Class H02J 3/24 (20130101)
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10291199 — Direct write sensors

US 10291199	McIntyre
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Timothy J. McIntyre (Farragut, Tennessee)
ABSTRACT	A method of making an acoustic wave sensor includes the steps of providing a piezoelectric substrate layer and printing on the substrate layer a sensor layer comprising a first interdigitated acoustic wave transducer, a sensing film, and positioned on an opposing side of the sensing film from the first interdigitated acoustic wave transducer at least one selected from the group consisting of a second interdigitated acoustic wave transducer and a Bragg reflector. An insulation layer can be printed. An antenna can be printed in an antenna layer, and the insulation layer can be interposed between the antenna layer and the sensor layer. An electrical connection can be printed between the antenna and the first interdigitated acoustic wave transducer. An acoustic wave sensor is also disclosed.
FILED	Thursday, August 25, 2016
APPL NO	15/246907
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/022 (20130101) G01N 29/22 (20130101) G01N 2291/0255 (20130101) G01N 2291/0256 (20130101) G01N 2291/0423 (20130101) G01N 2291/0426 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/314 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/02007 (20130101) H03H 9/02275 (20130101) H03H 9/02535 (20130101) Original (OR) Class
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10291399 — Quantum-secured communications overlay for optical fiber communications networks

US 10291399	Nordholt et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Traid National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Jane Elizabeth Nordholt (Los Alamos, New Mexico); Richard John Hughes (Los Alamos, New Mexico); Charles Glen Peterson (Los Alamos, New Mexico); Raymond Thorson Newell (Santa Fe, New Mexico)
ABSTRACT	Quantum secure communication systems communicate quantum signals for quantum key distribution and classical signals with encrypted data and commands via a single optical fiber. In some systems, the single fiber carries classical data in both directions along with quantum communications. For example, quantum keys can be used to encrypt packets for bidirectional communication between two parties. In other systems, a single fiber is used for one way classical communications and quantum communications. The communication systems are secured using a security parameter based on the quantum and classical communications across the optical fiber.
FILED	Tuesday, September 30, 2014
APPL NO	15/026001
ART UNIT	2433 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0852 (20130101) Original (OR) Class
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10291711 — Real-time predictive sensor network and deployable sensor

US 10291711	Hehlen et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Markus Hehlen (Los Alamos, New Mexico); Michael Brown (Los Alamos, New Mexico); Janette Frigo (Los Alamos, New Mexico); William Priedhorsky (Los Alamos, New Mexico)
ABSTRACT	Deployable, predictive sensor systems may form a sensor network configured to provide environmental data in real-time or near-real-time. The sensors may be deployable sensors that can be launched and/or airdropped in areas that may be contaminated or otherwise unsafe for humans to enter. The predictive sensor network may include sensor tetrapods that may include anemometers for measuring wind speed, radiation sensors, gaseous contaminant sensors, biological sensors, and/or any other desired sensor type. These sensors may inform wind, transport and dispersion models in real-time. The sensor tetrapods may be satellite-linked, linked via a cellular network, linked via RF line-of-sight, a wireless communication link, and/or another compatible wireless network to a wind, dispersal, and deposition model that provides a dispersion pattern, a deposition pattern, and a wind pattern to enable a high-quality remote assessment of the changing scene in real-time.
FILED	Thursday, January 11, 2018
APPL NO	15/868517
ART UNIT	2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 9/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) Original (OR) Class Selecting H04Q 9/02 (20130101) H04Q 2209/25 (20130101) H04Q 2209/40 (20130101) H04Q 2209/86 (20130101) H04Q 2209/826 (20130101) H04Q 2209/883 (20130101) Wireless Communication Networks H04W 52/0258 (20130101) H04W 84/18 (20130101)
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10292261 — Stretchable and foldable electronic devices

US 10292261	Rogers et al.
FUNDED BY	Department of Energy (DOE) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois); Northwestern University (Evanston, Illinois)
INVENTOR(S)	John A Rogers (Champaign, Illinois); Yonggang Huang (Glencoe, Illinois); Heung Cho Ko (Urbana, Illinois); Mark Stoykovich (Dover, New Hampshire); Won Mook Choi (Champaign, Illinois); Jizhou Song (Evanston, Illinois); Jong Hyun Ahn (Gyeonggi-do, South Korea); Dae Hyeong Kim (Champaign, Illinois)
ABSTRACT	Disclosed herein are stretchable, foldable and optionally printable, processes for making devices and devices such as semiconductors, electronic circuits and components thereof that are capable of providing good performance when stretched, compressed, flexed or otherwise deformed. Strain isolation layers provide good strain isolation to functional device layers. Multilayer devices are constructed to position a neutral mechanical surface coincident or proximate to a functional layer having a material that is susceptible to strain-induced failure. Neutral mechanical surfaces are positioned by one or more layers having a property that is spatially inhomogeneous, such as by patterning any of the layers of the multilayer device.
FILED	Thursday, May 07, 2015
APPL NO	14/706733
ART UNIT	2848 — Electrical Circuits and Systems
CURRENT CPC	Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4867 (20130101) H01L 21/6835 (20130101) H01L 23/4985 (20130101) H01L 25/50 (20130101) H01L 25/0655 (20130101) H01L 27/14601 (20130101) H01L 2221/68359 (20130101) H01L 2224/05624 (20130101) H01L 2924/00 (20130101) H01L 2924/01019 (20130101) H01L 2924/01046 (20130101) H01L 2924/01057 (20130101) H01L 2924/01079 (20130101) H01L 2924/1461 (20130101) H01L 2924/1461 (20130101) H01L 2924/3025 (20130101) H01L 2924/09701 (20130101) H01L 2924/12044 (20130101) H01L 2924/13091 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/03 (20130101) H05K 1/16 (20130101) H05K 1/028 (20130101) Original (OR) Class H05K 1/036 (20130101) H05K 1/111 (20130101) H05K 1/118 (20130101) H05K 1/185 (20130101) H05K 1/0283 (20130101) H05K 1/0393 (20130101) H05K 3/30 (20130101) H05K 3/207 (20130101) H05K 3/284 (20130101) H05K 2201/0133 (20130101) H05K 2203/0271 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4913 (20150115) Y10T 29/49002 (20150115) Y10T 29/49146 (20150115)
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National Science Foundation (NSF)

10285961 — Organic acids as agents to dissolve calcium minerals in pathological calcification and uses thereof

US 10285961	Rimer et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Jeffrey D. Rimer (Houston, Texas); Jihae Chung (Houston, Texas); John Asplin (Chicago, Illinois)
ASSIGNEE(S)	University of Houston System (Houston, Texas)
INVENTOR(S)	Jeffrey D. Rimer (Houston, Texas); Jihae Chung (Houston, Texas); John Asplin (Chicago, Illinois)
ABSTRACT	In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.
FILED	Monday, April 27, 2015
APPL NO	14/696863
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/194 (20130101) Original (OR) Class A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 59/245 (20130101)
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10285978 — Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio

US 10285978	Bassler et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)	The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S)	Bonnie L. Bassler (Princeton, New Jersey); Lark J. Perez (Ewing, New Jersey); Martin F. Semmelhack (Princeton, New Jersey)
ABSTRACT	A structurally distinct and potent series of synthetic small molecule activators of Vibrio cholerae quorum sensing have been chemically synthesized. The small molecule activators reduce virulence in V. cholerae. Acyl pyrrole molecules displayed strong potency and stability, particularly 1-(1H-pyrrol-3-yl)decan-1-one.
FILED	Wednesday, November 29, 2017
APPL NO	15/825597
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/36 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) A61K 31/53 (20130101) A61K 31/401 (20130101) Original (OR) Class A61K 31/401 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 207/333 (20130101) Technologies for Adaptation to Climate Change Y02A 50/471 (20180101)
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10286088 — Multifunctional infrared-emitting composites

US 10286088	Naczynski et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Dominik J. Naczynski (Wallington, New Jersey); Mei-Chee Tan (Singapore, Singapore); Richard E. Riman (Belle Mead, New Jersey); Charles Roth (Princeton, New Jersey); Prabhas V. Moghe (Basking Ridge, New Jersey)
ASSIGNEE(S)	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S)	Dominik J. Naczynski (Wallington, New Jersey); Mei-Chee Tan (Singapore, Singapore); Richard E. Riman (Belle Mead, New Jersey); Charles Roth (Princeton, New Jersey); Prabhas V. Moghe (Basking Ridge, New Jersey)
ABSTRACT	Disclosed is a method of non-invasive infrared imaging, comprising (a) administering a composition containing infrared-emitting particles which contain rare earth elements that emit in the short-wavelength infrared (SWIR) spectrum, where the particles are encapsulated with a biocompatible matrix to form downconverting encapsulated particles; and (b) irradiating with infrared radiation, where both excitation and emission spectra of the encapsulated particles are in the infrared region. Analogous methods of image-guided biomedical intervention, and drug tracking and delivery are also disclosed. Also disclosed is a composition for biomedical applications, containing infrared-emitting particles which contain rare earth-elements that emit in the short-wavelength infrared (SWIR) spectrum, where the particles are encapsulated with a biocompatible matrix to form downconverting encapsulated particles.
FILED	Monday, May 07, 2012
APPL NO	14/115752
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0065 (20130101) Original (OR) Class
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10286197 — Patient-specific temporary implants for accurately guiding local means of tumor control along patient-specific internal channels to treat cancer

US 10286197	Pouliot et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Jean Pouliot (Mill Valley, California); Ken Goldberg (Mill Valley, California); I-Chow Hsu (San Francisco, California); J. Adam M. Cunha (San Bruno, California); Animesh Garg (Berkeley, California); Sachin Patil (Berkeley, California); Pieter Abbeel (Berkeley, California); Timmy Siauw (Berkeley, California)
ABSTRACT	The present invention offers an alternative for cancer treatment where radiation, thermotherapy, or another therapeutic modality must be delivered to an internal cavity of a subject, for example to treat mouth, anal, cervical, and vaginal cancers. The invention is a new approach that builds on recent results in 3D printing and steerable needle motion planning to create customized implants containing customized curvature-constrained internal channels that fit securely, minimize air gaps, and precisely guide treatment sources through internal printed channels to accurately reach tumors and minimize damage to healthy tissue.
FILED	Monday, July 28, 2014
APPL NO	14/907679
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 8/085 (20130101) A61B 18/14 (20130101) A61B 18/1815 (20130101) A61B 2018/0212 (20130101) A61B 2018/00559 (20130101) A61B 2018/00577 (20130101) A61B 2018/00791 (20130101) A61B 2018/1861 (20130101) A61B 2090/3983 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2007/126 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/002 (20130101) Original (OR) Class A61M 2207/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0603 (20130101) A61N 5/1014 (20130101) A61N 5/1016 (20130101) A61N 5/1049 (20130101) A61N 7/022 (20130101) A61N 2005/0606 (20130101) A61N 2005/0608 (20130101) A61N 2005/0611 (20130101) A61N 2005/1018 (20130101) A61N 2005/1094 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/20 (20170801) B29C 64/112 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/12 (20130101) B29K 2995/0056 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201)
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10286364 — Mixed matrix membranes for olefin/paraffin separation and method of making thereof

US 10286364	Tang et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	BETTERGY CORP. (Peekskill, New York)
ASSIGNEE(S)	BETTERGY CORP. (Peekskill, New York)
INVENTOR(S)	Zhong Tang (Pompton Plains, New Jersey); Bo Lu (Croton on Hudson, New York); Xiaojuan Hu (Croton on Hudson, New York); Tuyen Pham (Camden, New Jersey); Lin-Feng Li (Croton on Hudson, New York)
ABSTRACT	The invention provides mixed matrix membranes (MMMs) for olefin/paraffin separation and methodes of making and using the same. The MMMs comprise a continuous polymer matrix with metal doped zeolite nano-particles. A separation technology based upon the composite membranes is effective for propylene and other olefin separation from olefin/paraffin mixtures, and the separation is more energy-efficient than the conventional cryogenic technique.
FILED	Monday, April 10, 2017
APPL NO	15/482942
ART UNIT	1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/228 (20130101) B01D 63/10 (20130101) B01D 67/0016 (20130101) B01D 67/0079 (20130101) B01D 69/04 (20130101) B01D 69/08 (20130101) B01D 69/148 (20130101) B01D 71/028 (20130101) B01D 71/34 (20130101) B01D 71/48 (20130101) B01D 71/52 (20130101) B01D 71/56 (20130101) B01D 71/64 (20130101) B01D 71/68 (20130101) Original (OR) Class B01D 2256/24 (20130101) B01D 2257/702 (20130101) Acyclic or Carbocyclic Compounds C07C 7/144 (20130101)
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10286382 — Silver nanowires, methods of making silver nanowires, core-shell nanostructures, methods of making core-shell nanostructures, core-frame nanostructures, methods of making core-frame nanostructures

US 10286382	Qin et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S)	GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
INVENTOR(S)	Dong Qin (Atlanta, Georgia); Younan Xia (Atlanta, Georgia); Yin Yang (Atlanta, Georgia); Jumei Li (Atlanta, Georgia); Xiaojun Sun (Atlanta, Georgia); Robson Rosa da Silva (Inhumas Goiás, Brazil); Miaoxin Yang (Atlanta, Georgia)
ABSTRACT	In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure provide for silver nanowires, methods of making silver nanowires, core-shell nanostructures, methods of making core-shell nanostructures, core-frame nanostructures, methods of making core-frame nanostructures, and the like.
FILED	Tuesday, October 10, 2017
APPL NO	15/728619
ART UNIT	1788 — Miscellaneous Articles, Stock Material
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/50 (20130101) Original (OR) Class B01J 35/002 (20130101) B01J 35/06 (20130101) B01J 35/008 (20130101) B01J 35/0013 (20130101) B01J 35/023 (20130101) B01J 35/026 (20130101) B01J 37/16 (20130101) B01J 37/0219 (20130101) B01J 37/0225 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0025 (20130101) B22F 9/24 (20130101) B22F 9/26 (20130101) B22F 2001/0037 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/02 (20130101) C23F 1/30 (20130101)
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10286713 — Printing using reactive inks and conductive adhesion promoters

US 10286713	Hildreth et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Owen Hildreth (Tempe, Arizona); April Jeffries (Tempe, Arizona); Avinash Mamidanna (Tempe, Arizona); Mariana Bertoni (Mesa, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Owen Hildreth (Tempe, Arizona); April Jeffries (Tempe, Arizona); Avinash Mamidanna (Tempe, Arizona); Mariana Bertoni (Mesa, Arizona)
ABSTRACT	Methods and chemistries are described to form electrically conductive adhesion promoters for use with reactive inks. In some implementations, a metal ink is printed on a substrate. An adhesion promoter is deposited on the surface of the substrate. The adhesion promoter reacts to form a covalent bond with the substrate. Subsequently, a reactive metal ink is used to print on a substrate using a drop-on-demand printing process. The reactive metal ink includes metal cations that react with the adhesion promoter-treated substrate surface to form a conductive bond between the adhesion promoter-treated substrate surface and a metal of the reactive metal ink.
FILED	Wednesday, October 11, 2017
APPL NO	15/729978
ART UNIT	2823 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/17 (20130101) B41J 2/04505 (20130101) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 5/0011 (20130101) B41M 5/0017 (20130101) B41M 5/0023 (20130101) B41M 7/009 (20130101) Original (OR) Class
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10287332 — Self-assembled beta solenoid protein scaffolds

US 10287332	Cox et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Daniel Cox (Oakland, California); Gang-Yu Liu (Oakland, California); Michael Toney (Oakland, California); Xi Chen (Oakland, California); Josh Hihath (Oakland, California); Gergely Zimanyi (Oakland, California); Natha Robert Hayre (Oakland, California); Maria Peralta (Oakland, California)
ABSTRACT	The present invention provides amyloid fibrils comprising a plurality of modified β solenoid protein (mBSP) monomers. The mBSP monomers are modified to enhance self-assembly and are useful in a variety of applications.
FILED	Monday, January 26, 2015
APPL NO	15/111687
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 14/47 (20130101) C07K 14/415 (20130101) C07K 14/43563 (20130101) Original (OR) Class
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10287376 — Anisotropic and amphiphilic particles and methods for producing and using the same

US 10287376	Lee et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustee of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Daeyeon Lee (Wynnewood, Pennsylvania); Fuquan Tu (Philadelphia, Pennsylvania)
ABSTRACT	A method for producing an amphiphilic particle or an anisotropic particle includes combining seed particles with a monomer emulsion to obtain monomer-swollen seed particles, polymerizing the monomer-swollen seed particles to obtain polymerized monomer-swollen particles, and hydrolyzing the polymerized monomer-swollen particles. An amphiphilic particle is adapted to stabilize a first type of multiphasic mixture comprising a first aqueous phase having a first pH and a second type of multiphasic mixture comprising a second aqueous phase having a second pH.
FILED	Thursday, January 12, 2017
APPL NO	15/404549
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/00 (20130101) C08F 212/08 (20130101) Original (OR) Class C08F 220/06 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/05 (20130101) C08J 2325/06 (20130101) C08J 2333/02 (20130101)
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10287573 — Combinatorial DNA taggants and methods of preparation and use thereof

US 10287573	Macula
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Research Laboratory (AFRL) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	JEANSEE LLC (Geneseo, New York)
ASSIGNEE(S)	JEANSEE LLC (Geneseo, New York)
INVENTOR(S)	Anthony J. Macula (Geneseo, New York)
ABSTRACT	DNA taggants in which the nucleotide sequences are defined according to combinatorial mathematical principles. Methods of defining nucleotide sequences of the combinatorial DNA taggants, and using such taggants for authentication and tracking and tracing an object or process are also disclosed.
FILED	Monday, April 14, 2014
APPL NO	14/251690
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6876 (20130101) C12Q 2563/185 (20130101)
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10287677 — Methods of fabricating pillared graphene nanostructures

US 10287677	Ozkan et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR) Nanoscale Science and Engineering Centers (NSF-NSEC) Materials Research Science and Engineering Centers (MRSECs)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Cengiz S. Ozkan (San Diego, California); Mihrimah Ozkan (San Diego, California); Ali B. Guvenc (San Diego, California); Rajat K. Paul (San Diego, California); Jian Lin (San Diego, California); Maziar Ghazinejad (San Diego, California); Miro Penchev (San Diego, California); Shirui Guo (San Diego, California); Jiebin Zhong (San Diego, California)
ABSTRACT	Methods of fabricating a graphene film are disclosed. An example method can include providing a substrate, heating the substrate between about 600° C. and about 1100° C. in a chamber, and introducing a carbon source into the chamber at a temperature between about 600° C. and about 1100° C. for about 10 seconds to about 1 minute. The method can further include cooling the substrate to about room temperature to form the graphene film Methods of fabricating pillared graphene nano structures and graphene based devices are also provided.
FILED	Monday, November 18, 2013
APPL NO	14/443300
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/186 (20170801) C01B 2204/04 (20130101) C01B 2204/22 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) C23C 16/44 (20130101) Original (OR) Class Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/008 (20130101) H01G 9/20 (20130101) H01G 9/042 (20130101) H01G 9/145 (20130101) H01G 9/2031 (20130101) H01G 9/2072 (20130101) H01G 11/36 (20130101) H01G 11/52 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02491 (20130101) H01L 21/02527 (20130101) H01L 21/02664 (20130101) H01L 27/302 (20130101) H01L 29/413 (20130101) H01L 29/0673 (20130101) H01L 29/1606 (20130101) H01L 29/7781 (20130101) H01L 31/028 (20130101) H01L 31/068 (20130101) H01L 31/076 (20130101) H01L 31/1804 (20130101) H01L 51/0048 (20130101) H01L 51/424 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/542 (20130101) Y02E 10/547 (20130101) Y02E 10/548 (20130101) Y02E 60/13 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101)
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10288420 — Laser speckle photography for surface tampering detection

US 10288420	Shih et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	YiChang Shih (Cambridge, Massachusetts); Myers Abraham Davis (Cambridge, Massachusetts); Samuel Wiliam Hasinoff (Sunnyvale, California); Frederic Durand (Boston, Massachusetts); William T. Freeman (Acton, Massachusetts)
ABSTRACT	In one embodiment, a method comprises projecting, from a projector, a diffused on an object. The method further includes capturing, with a first camera in a particular location, a reference image of the object while the diffused is projected on the object. The method further includes capturing, with a second camera positioned in the particular location, a test image of the object while the diffused is projected on the object. The method further includes comparing speckles in the reference image to the test image. The projector, first camera and second camera are removably provided to and positioned in a site of the object.
FILED	Friday, July 31, 2015
APPL NO	14/815092
ART UNIT	2422 — Cable and Television
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/254 (20130101) G01B 11/303 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6215 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) Pictorial Communication, e.g Television H04N 7/18 (20130101)
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10288563 — Sensor platform based on toroidal resonances for rapid detection of biomolecules

US 10288563	Ahmadivand et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Arash Ahmadivand (Miami, Florida); Raju Sinha (Miami, Florida); Burak Gerislioglu (Miami, Florida); Nezih Pala (Fort Lauderdale, Florida)
ASSIGNEE(S)	The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S)	Arash Ahmadivand (Miami, Florida); Raju Sinha (Miami, Florida); Burak Gerislioglu (Miami, Florida); Nezih Pala (Fort Lauderdale, Florida)
ABSTRACT	A plasmonic resonator can include: a substrate; a central resonator on the substrate; a first curved resonator disposed on the substrate and disposed at a first side of the central resonator; and a second curved resonator disposed on the substrate and disposed at a second side of the central resonator, the first curved resonator and the second curved resonator being asymmetric to each other with respect to the central resonator, and the central resonator and at least one of the first and second curved resonators being made of different materials.
FILED	Monday, January 22, 2018
APPL NO	15/876481
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) Original (OR) Class G01N 21/3581 (20130101) G01N 33/56983 (20130101) G01N 2333/185 (20130101)
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10288672 — Monitoring aging of power semiconductor devices based on case temperature

US 10288672	Qiao et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S)	NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S)	Wei Qiao (Lincoln, Nebraska); Ze Wang (Kokomo, Indiana); Liyan Qu (Lincoln, Nebraska)
ABSTRACT	The aging of an electronic component in an electronic power converter can be monitored based on two or more case temperature measurements. A power electronic device is enclosed in a package having a baseplate, in which the power electronic device generates heat during operation and the baseplate transfers heat to a heat dissipating device or a cooling device. Sensors measure temperatures at first and second locations on a surface of the baseplate. A data processor calculates a value for a first parameter based on the temperatures at the first and second locations, in which the first parameter is indicative of an aging process of the power electronic device, and generates a first signal based on a comparison of the calculated value and a first predetermined threshold. The data processor calculates a value for a second parameter based on the first parameter value, a predetermined look-up table, and the temperatures at the first and second locations, in which the second parameter is indicative of another aging process of the semiconductor switching devices, and generates a second signal based on a comparison of the calculated value and a second predetermined threshold.
FILED	Friday, April 07, 2017
APPL NO	15/482276
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2619 (20130101) G01R 31/2642 (20130101) Original (OR) Class
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10288804 — Method to fabricate chip-scale electronic photonic (plasmonic)-integrated circuits

US 10288804	Bao et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	University of Houston System (Houston, Texas)
ASSIGNEE(S)	UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S)	Jiming Bao (Pearland, Texas); Zhuan Zhu (Houston, Texas); Zhiming Wang (Katy, Texas)
ABSTRACT	Electronic-photonic integrated circuits (EPICs), such a monolithically integrated circuit, are considered to be next generation technology that takes advantage of high-speed optical communication and nanoscale electronics. Atomically thin transition metal dichalcogenides (TMDs) may serve as a perfect platform to realize EPIC. The generation and detection of light by a monolayer TMD at nanoscale through surface plasmon polaritons (SPPs) may be utilized to provide optical communication. The bidirectional nature of the TMDs allow such a layer to be utilizes as part of emitters or photodetectors for EPICs.
FILED	Wednesday, July 06, 2016
APPL NO	15/736941
ART UNIT	2874 — Optics
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 19/007 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 39/06 (20130101) C01G 41/00 (20130101) Optical Elements, Systems, or Apparatus G02B 6/30 (20130101) G02B 6/107 (20130101) G02B 6/1226 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/022408 (20130101) H01L 33/38 (20130101)
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10289146 — Reconfigurable dickson star switched capacitor voltage regulator

US 10289146	Puggelli et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Lion Semiconductor Inc. (San Francisco, California)
ASSIGNEE(S)	Lion Semiconductor Inc. (San Francisco, California)
INVENTOR(S)	Alberto Alessandro Angelo Puggelli (Oakland, California); Thomas Li (Mountain View, California); Wonyoung Kim (Berkeley, California); John Crossley (Oakland, California); Hanh-Phuc Le (Richmond, California)
ABSTRACT	The present disclosure shows a reconfigurable Dickson Star SC regulator that can support multiple conversion ratios by reconfiguring between various modes. The reconfigurable Dickson Star SC regulator is designed to reduce the number of redundant capacitors by reusing capacitors and switches across multiple modes of operation (across multiple conversion ratios). The present disclosure also shows a hybrid (e.g., two-stage) voltage regulator.
FILED	Friday, April 14, 2017
APPL NO	15/487682
ART UNIT	2859 — Printing/Measuring and Testing
CURRENT CPC	Systems for Regulating Electric or Magnetic Variables G05F 5/00 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0052 (20130101) H02J 7/0065 (20130101) H02J 2007/0062 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/07 (20130101) H02M 3/1582 (20130101) H02M 2001/007 (20130101)
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10289604 — Memory processing core architecture

US 10289604	Sankaralingam et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Karthikeyan Sankaralingam (Madison, Wisconsin); Jaikrishnan Menon (Madison, Wisconsin); Lorenzo De Carli (Madison, Wisconsin)
ABSTRACT	Aspects of the present invention provide a memory system comprising a plurality of stacked memory layers, each memory layer divided into memory sections, wherein each memory section connects to a neighboring memory section in an adjacent memory layer, and a logic layer stacked among the plurality of memory layers, the logic layer divided into logic sections, each logic section including a memory processing core, wherein each logic section connects to a neighboring memory section in an adjacent memory layer to form a memory vault of connected logic and memory sections, and wherein each logic section is configured to communicate directly or indirectly with a host processor. Accordingly, each memory processing core may be configured to respond to a procedure call from the host processor by processing data stored in its respective memory vault and providing a result to the host processor. As a result, increased performance may be provided.
FILED	Thursday, August 07, 2014
APPL NO	14/453990
ART UNIT	2194 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 15/7821 (20130101) Original (OR) Class Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/12 (20180101) Y02D 10/13 (20180101)
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10289650 — Active stability devices and systems for mobile devices

US 10289650	Pearlman et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburg, Pennsylvania); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Jonathan L. Pearlman (Pittsburgh, Pennsylvania); Jonathan Aaron Duvall (Pittsburgh, Pennsylvania); Benjamin Todd Gebrosky (Gibsonia, Pennsylvania); Rory Alan Cooper (Gibsonia, Pennsylvania)
ABSTRACT	A system for use with a mobile device includes at least one sensor to sense a variable related to tilting of the mobile device and at least one activatable system in operative connection with the sensor. The at least one activatable system increases stability of the mobile device upon actuation/change in state thereof on the basis of data measured by the at least one sensor. A variable related to tilting includes variables that indicate concurrent, actual tilting as described herein as well as variables predictive of imminent tilting. Activatable systems hereof change state upon actuation or activation to increase stability of the mobile device by reducing, eliminating or preventing tilting.
FILED	Thursday, September 22, 2016
APPL NO	15/273116
ART UNIT	3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/00 (20130101) A61G 5/043 (20130101) A61G 5/063 (20130101) A61G 5/068 (20130101) A61G 5/128 (20161101) A61G 5/1054 (20161101) A61G 5/1089 (20161101) A61G 2203/14 (20130101) A61G 2203/42 (20130101) Electric Digital Data Processing G06F 17/00 (20130101) Original (OR) Class
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10289875 — Embedding data on objects using surface modulation

US 10289875	Singh et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Portland State University (Portland, Oregon)
ASSIGNEE(S)	Portland State University (Portland, Oregon)
INVENTOR(S)	Suresh Singh (Portland, Oregon); Farnoosh Moshirfatemi (Portland, Oregon)
ABSTRACT	Methods and apparatus are disclosed for embedding static information (such as serial numbers, etc.) on objects by modifying their exterior shape slightly, dubbed surface modulation. Data is embedded when the object is created and can then be read using readers with the appropriate resolution. According to one example of the disclosed technology, a method of embedding data expressed as a binary sequence onto an object surface includes establishing a coordinate system over an object surface, computing a transform of the coordinate system to a frequency domain, mapping the binary sequence to an integer value, replacing the highest frequency coefficient of the transform with the integer value, computing an inverse of the transform, producing a vector expressed in the coordinate system, and fabricating at least a portion of the object surface according to the vector.
FILED	Friday, July 22, 2016
APPL NO	15/746275
ART UNIT	2887 — Optics
CURRENT CPC	Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 50/00 (20141201) B33Y 80/00 (20141201) Electric Digital Data Processing G06F 17/141 (20130101) G06F 17/147 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 1/12 (20130101) G06K 1/121 (20130101) Original (OR) Class G06K 7/10 (20130101) G06K 7/10712 (20130101) G06K 19/06 (20130101) G06K 19/06159 (20130101) G06K 2019/06271 (20130101)
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10289955 — Systems and methods for predicting meme virality based on network structure

US 10289955	Menczer et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S)	Filippo Menczer (Bloomington, Indiana); Lilian Weng (Bloomington, Indiana); Yong Yeol Ahn, Jr. (Bloomington, Indiana)
ABSTRACT	Systems and methods for predicting virality of a content item are disclosed. A method includes: receiving a social network structure; identifying communities within the social network structure, where communities are identified as dense subnetworks in the social network structure; receiving social network content that includes one or more content items; and identifying one or more content items that are predicted to become viral based on utilization of the content items between different communities in the social network structure.
FILED	Wednesday, March 12, 2014
APPL NO	14/775403
ART UNIT	2124 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0202 (20130101) G06Q 50/01 (20130101)
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10290230 — Device specific finite element models for simulating endovascular treatment

US 10290230	Babiker et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona); Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); MAYO FOUNDATION FOR MEDICAL EDUCATION and RESEARCH (Rochester, Minnesota)
INVENTOR(S)	Mohamed Haithem Babiker (Tempe, Arizona); David H. Frakes (Scottsdale, Arizona); Brian W. Chong (Scottsdale, Arizona)
ABSTRACT	Systems and methods provide a novel computational approach to planning the endovascular treatment of cardiovascular diseases. In particular, the invention simulates medical device deployment and hemodynamic outcomes using a virtual patient-specific anatomical model of the area to be treated, high-fidelity finite element medical device models and computational fluid dynamics (CFD). In an embodiment, the described approach investigates the effects of coil packing density, coil shape, aneurysmal neck size and parent vessel flow rate on aneurysmal hemodynamics. A processor may receive patient clinical data used to construct the relevant anatomical structure model. The processor may access medical device models constructed using finite element analysis and three dimensional beam analysis, and simulates the deployment of selected medical devices in the anatomical structure model. The selected medical device models and the anatomical structure model mesh, allowing the processor to simulate hemodynamic outcomes using computational fluid dynamics.
FILED	Monday, January 26, 2015
APPL NO	14/605887
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/02 (20130101) G09B 23/28 (20130101) Original (OR) Class
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10290233 — Physical deformable lung phantom with subject specific elasticity

US 10290233	Santhanam et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
INVENTOR(S)	Anand P. Santhanam (Culver City, California); Olusegun Ilegbusi (Oviedo, Florida)
ABSTRACT	A system and method to integrate computational fluid dynamics (CFD) and radiotherapy data for accurate simulation of spatio-temporal flow and deformation in real human lung is presented. The method utilizes a mathematical formulation that fuses the CFD predictions of lung displacement with the corresponding radiotherapy data using the theory of Tikhonov regularization.
FILED	Wednesday, July 13, 2016
APPL NO	15/208876
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/50 (20130101) A61B 6/466 (20130101) A61B 6/583 (20130101) A61B 6/5211 (20130101) A61B 34/10 (20160201) A61B 2034/105 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1075 (20130101) A61N 2005/1076 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Image Data Processing or Generation, in General G06T 7/251 (20170101) G06T 2207/10076 (20130101) G06T 2207/10081 (20130101) G06T 2207/30061 (20130101) G06T 2207/30076 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 23/28 (20130101) G09B 23/30 (20130101) Original (OR) Class G09B 23/286 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101)
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10290387 — Modification of colloidal nanocrystals

US 10290387	Risbud Bartl et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Electrical and Communications Systems (ECS)
APPLICANT(S)	University of Utah Research Foundation (, None)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Michael Hans Risbud Bartl (Cupertino, California); Jacqueline T. Siy (Salt Lake City, Utah)
ABSTRACT	Methods for precise and predictable modification of previously synthesized nanocrystals. The methods rely on the solubility behavior of crystalline materials to provide for controlled reversal of the nanocrystal growth process (i.e., dissolution). A method for post-synthesis modification of colloidal nanocrystals includes (1) providing a first nanocrystal having a first size and a first shape, (2) forming a reaction mixture that includes the nanocrystal, at least one ligand capable of binding to at least one component of the nanocrystal, at least one solvent, and an inert gas atmosphere, and (3) modifying the size and/or shape of the nanocrystal in the reaction mixture for a period of time at a temperature in a range from about 100° C. to about 240° C. so as to produce at least a second nanocrystal having a second size and/or a second shape.
FILED	Tuesday, July 28, 2015
APPL NO	14/811715
ART UNIT	1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/00 (20130101) C07F 7/24 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/88 (20130101) C09K 11/883 (20130101) C09K 2211/10 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/12 (20130101) Original (OR) Class
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10290753 — Mid-infrared photodetectors

US 10290753	Guyot-Sionnest et al.
FUNDED BY	Department of Energy (DOE) National Science Foundation (NSF)
APPLICANT(S)	The University of Chicago (Chicago, Illinois)
ASSIGNEE(S)	The University of Chicago (Chicago, Illinois)
INVENTOR(S)	Philippe Guyot-Sionnest (Chicago, Illinois); Sean E. Keuleyan (Chicago, Illinois); Emmanuel Lhuillier (Chicago, Illinois)
ABSTRACT	Nanoparticles, methods of manufacture, devices comprising the nanoparticles, methods of their manufacture, and methods of their use are provided herein. The nanoparticles and devices having photoabsorptions in the range of 1.7 μm to 12 μm and can be used as photoconductors, photodiodes, phototransistors, charge-coupled devices (CCD), luminescent probes, lasers, thermal imagers, night-vision systems, and/or photodetectors.
FILED	Monday, March 07, 2016
APPL NO	15/062418
ART UNIT	2884 — Optics
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/89 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/4228 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/146 (20130101) H01L 31/09 (20130101) H01L 31/0272 (20130101) H01L 31/0296 (20130101) Original (OR) Class H01L 31/0324 (20130101) H01L 31/1828 (20130101) H01L 31/035218 (20130101)
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10290869 — Doped lithium-rich layered composite cathode materials

US 10290869	Axelbaum et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Washington University (St. Louis, Missouri)
ASSIGNEE(S)
INVENTOR(S)	Richard L. Axelbaum (St. Louis, Missouri); Miklos Lengyel (St. Louis, Missouri)
ABSTRACT	A layered composite composition having a general chemical formula of Li_α-xAD_x(Mn_β-y-εAl_yNi_γ-εCo_δ-zAED_z)O₂, wherein AD is an alkaline dopant for Li, AED is an alkaline earth dopant for Co or Ni, and Al is a dopant for Mn or Ni, and at least two of AD, AED, and Al are present in the composition, and the dopants, if present, are at an amount that does not result in the formation of new phase.
FILED	Friday, March 20, 2015
APPL NO	14/664632
ART UNIT	1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/50 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/50 (20130101) C01P 2004/61 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) C01P 2006/12 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) Original (OR) Class H01M 2004/021 (20130101)
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10291076 — Misalignment insensitive wireless power transfer with cylindrical, spherical and conical transmitter and receiver elements

US 10291076	Georgakopoulos
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Stavros Georgakopoulos (Miami, Florida)
ASSIGNEE(S)	The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S)	Stavros Georgakopoulos (Miami, Florida)
ABSTRACT	Wireless power transfer systems including wireless transmitter and receivers, which are insensitive to misalignment, are provided. A wireless power transfer system can include a first conductive loop that has cylindrical, conical, or spherical symmetry. The wireless power transfer system can further include a second conductive loop that is formed around the first conductive loop, and can also share the same type of symmetry as the first conductive loop. The wireless transfer system can be a wearable device or an implantable device.
FILED	Tuesday, May 15, 2018
APPL NO	15/979902
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/2804 (20130101) H01F 38/14 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/12 (20160201) Original (OR) Class Transmission H04B 5/0037 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/028 (20130101) H05K 1/165 (20130101) H05K 1/0284 (20130101) H05K 1/0393 (20130101) H05K 3/103 (20130101)
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10291696 — Peer-to-peer architecture for processing big data

US 10291696	Ying et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Tempe, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona)
INVENTOR(S)	Lei Ying (Tempe, Arizona); Weina Wang (Tempe, Arizona); Matthew Barnard (Tempe, Arizona)
ABSTRACT	A system is disclosed for managing large datasets. The system comprises a physical network. The physical network comprises a plurality of computing devices with a plurality of processors. The system further comprises a logical peer-to-peer (P2P) network with a plurality of nodes. The system further comprises a distributed file system for distributing data and jobs received by the system randomly across the plurality of nodes in the P2P network. The system duplicates the data to neighboring nodes of the plurality of nodes. The nodes monitor each other to reduce loss of data. The system further comprises a task scheduler. The task scheduler balances load across the plurality of nodes as tasks, derived from jobs, are distributed to various nodes. The task scheduler redistributes and forwards tasks to ensure the nodes processing the tasks are best suited to process those tasks.
FILED	Tuesday, April 28, 2015
APPL NO	14/698672
ART UNIT	2447 — Computer Networks
CURRENT CPC	Electric Digital Data Processing G06F 9/5066 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/34 (20130101) H04L 67/104 (20130101) H04L 67/1061 (20130101) Original (OR) Class H04L 67/1065 (20130101) H04L 67/1076 (20130101)
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10292261 — Stretchable and foldable electronic devices

US 10292261	Rogers et al.
FUNDED BY	Department of Energy (DOE) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois); Northwestern University (Evanston, Illinois)
INVENTOR(S)	John A Rogers (Champaign, Illinois); Yonggang Huang (Glencoe, Illinois); Heung Cho Ko (Urbana, Illinois); Mark Stoykovich (Dover, New Hampshire); Won Mook Choi (Champaign, Illinois); Jizhou Song (Evanston, Illinois); Jong Hyun Ahn (Gyeonggi-do, South Korea); Dae Hyeong Kim (Champaign, Illinois)
ABSTRACT	Disclosed herein are stretchable, foldable and optionally printable, processes for making devices and devices such as semiconductors, electronic circuits and components thereof that are capable of providing good performance when stretched, compressed, flexed or otherwise deformed. Strain isolation layers provide good strain isolation to functional device layers. Multilayer devices are constructed to position a neutral mechanical surface coincident or proximate to a functional layer having a material that is susceptible to strain-induced failure. Neutral mechanical surfaces are positioned by one or more layers having a property that is spatially inhomogeneous, such as by patterning any of the layers of the multilayer device.
FILED	Thursday, May 07, 2015
APPL NO	14/706733
ART UNIT	2848 — Electrical Circuits and Systems
CURRENT CPC	Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4867 (20130101) H01L 21/6835 (20130101) H01L 23/4985 (20130101) H01L 25/50 (20130101) H01L 25/0655 (20130101) H01L 27/14601 (20130101) H01L 2221/68359 (20130101) H01L 2224/05624 (20130101) H01L 2924/00 (20130101) H01L 2924/01019 (20130101) H01L 2924/01046 (20130101) H01L 2924/01057 (20130101) H01L 2924/01079 (20130101) H01L 2924/1461 (20130101) H01L 2924/1461 (20130101) H01L 2924/3025 (20130101) H01L 2924/09701 (20130101) H01L 2924/12044 (20130101) H01L 2924/13091 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/03 (20130101) H05K 1/16 (20130101) H05K 1/028 (20130101) Original (OR) Class H05K 1/036 (20130101) H05K 1/111 (20130101) H05K 1/118 (20130101) H05K 1/185 (20130101) H05K 1/0283 (20130101) H05K 1/0393 (20130101) H05K 3/30 (20130101) H05K 3/207 (20130101) H05K 3/284 (20130101) H05K 2201/0133 (20130101) H05K 2203/0271 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4913 (20150115) Y10T 29/49002 (20150115) Y10T 29/49146 (20150115)
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10292263 — Biodegradable materials for multilayer transient printed circuit boards

US 10292263	Rogers et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S)	John A. Rogers (Champaign, Illinois); Xian Huang (Urbana, Illinois)
ABSTRACT	The invention provides transient printed circuit board devices, including active and passive devices that electrically and/or physically transform upon application of at least one internal and/or external stimulus.
FILED	Tuesday, August 04, 2015
APPL NO	14/818109
ART UNIT	2847 — Electrical Circuits and Systems
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/686 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/028 (20130101) H05K 1/095 (20130101) H05K 1/097 (20130101) H05K 1/144 (20130101) H05K 1/0212 (20130101) H05K 1/0275 (20130101) H05K 1/0283 (20130101) H05K 1/0286 (20130101) Original (OR) Class H05K 1/0386 (20130101) H05K 3/22 (20130101) H05K 3/207 (20130101) H05K 3/285 (20130101) H05K 3/287 (20130101) H05K 3/288 (20130101) H05K 3/1216 (20130101) H05K 3/4626 (20130101) H05K 2201/041 (20130101) H05K 2201/0133 (20130101) H05K 2201/0266 (20130101) H05K 2201/10083 (20130101) H05K 2201/10098 (20130101) H05K 2201/10151 (20130101) H05K 2201/10196 (20130101) H05K 2201/10212 (20130101) H05K 2203/105 (20130101) H05K 2203/175 (20130101) H05K 2203/178 (20130101) H05K 2203/0271 (20130101) H05K 2203/0292 (20130101) H05K 2203/0514 (20130101) H05K 2203/0769 (20130101) H05K 2203/0776 (20130101) H05K 2203/0786 (20130101) H05K 2203/1105 (20130101) H05K 2203/1142 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/611 (20151101) Y02P 70/613 (20151101) Technical Subjects Covered by Former US Classification Y10T 29/49124 (20150115) Y10T 137/0318 (20150401) Y10T 428/239 (20150115)
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Department of Veterans Affairs (DVA)

10285935 — Non-invasive method for direct delivery of therapeutics to the spinal cord in the treatment of spinal cord pathology

US 10285935	Garbuzova-Davis et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	Svitlana Garbuzova-Davis (Tampa, Florida); Cesario Venturina Borlongan (Tampa, Florida); Harry Ronald van Loveren (Tampa, Florida); Peter Richard Nelson (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida); United States Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Svitlana Garbuzova-Davis (Tampa, Florida); Cesario Venturina Borlongan (Tampa, Florida); Harry Ronald van Loveren (Tampa, Florida); Peter Richard Nelson (Tampa, Florida)
ABSTRACT	Most spinal cord therapies are administered systemically, with only a small portion of the therapeutic reaching the spinal cord. A novel method for delivering therapeutics directly to the spinal cord is provided. The method uses a dual balloon catheter to isolate the microvasculature around a region of the spinal cord. Once isolated, one or more therapeutics are delivered directly to the spinal cord blood supply. This allows for smaller, safer therapeutic dose to be utilized.
FILED	Tuesday, December 20, 2016
APPL NO	15/384808
ART UNIT	3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) Original (OR) Class A61K 9/0085 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/1011 (20130101) A61M 2025/1015 (20130101) A61M 2025/1052 (20130101)
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10286054 — Attenuated EHEC and clostridial toxins TcdA and TcdB based vaccine for Clostridium difficil associated disease (CDAD)

US 10286054	Boedeker et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Agriculture (USDA)
APPLICANT(S)	DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S)	Edgar C. Boedeker (Washington, District of Columbia); Sudeep Kumar (Washington, District of Columbia)
ABSTRACT	Provided are novel methods for expressing antigens in a vaccine vector strain, a live oral vaccine designed to prevent clostridium difficile-associated disease and methods for delivering antigens to the mucosal immune system of a subject.
FILED	Friday, October 11, 2013
APPL NO	14/435443
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/08 (20130101) Original (OR) Class A61K 2039/522 (20130101) A61K 2039/523 (20130101) A61K 2039/541 (20130101) Peptides C07K 14/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101)
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10286084 — Compositions for the inactivation of virus replication and methods of making and using the same

US 10286084	Cullen et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	DUKE UNIVERSITY (Durham, North Carolina); EMORY UNIVERSITY (Atlanta, Georgia)
ASSIGNEE(S)	Duke University (Durham, North Carolina); Emory University (Atlanta, Georgia); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Bryan R. Cullen (Durham, North Carolina); E. Matthew Kennedy (Durham, North Carolina); Hal P. Bogerd (Durham, North Carolina); Anand Kornepati (Durham, North Carolina); Adam Mefferd (Durham, North Carolina); Raymond F. Schinazi (Atlanta, Georgia)
ABSTRACT	Provided herein are recombinant constructs, vectors and expression cassettes including a first promoter which is suitably a tRNA promoter operably connected to a first polynucleotide encoding a first single guide RNA and a second promoter operably connected to a second polynucleotide encoding a Cas9 polypeptide. The first single guide RNA includes a first portion complementary to a strand of a target sequence of a DNA virus and a second portion capable of interacting with the Cas9 polypeptide. Also provided are codon optimized Staphylococcus aureus derived Cas9 polynucleotides and polypeptides with nuclear localization signals and optionally an epitope tag. Also provided are constructs for production of sgRNAs including a tRNA. Methods of inhibiting viral replication, inhibiting expression of a target sequence from a virus or treating a viral infection or viral induced cancer using the compositions are also provided.
FILED	Wednesday, February 18, 2015
APPL NO	15/119867
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 15/1131 (20130101) C12N 15/1132 (20130101) C12N 15/1133 (20130101) C12N 2310/20 (20170501) C12N 2740/15043 (20130101) C12N 2750/14143 (20130101)
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10286195 — Surgical drain sutured-in-place prevention device

US 10286195	Turner
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	University of Maryland, Baltimore (Baltimore, Maryland); THE UNITED STATES OF AMERICA AS REP. BY THE DEPT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S)	University of Maryland, Baltimore (Baltimore, Maryland); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Douglas Turner (Fulton, Maryland)
ABSTRACT	The present invention discloses systems and methods to alert a medical operator that a surgical drain has been sutured in place within a patient's body. A readily removable sheath is provided at a distal end of a surgical drain. The sheath is configured to be placed within a surgical wound along with the surgical drain, and after the surgical drain is placed, to be removed from the surgical drain and withdrawn from the patient's body, leaving the surgical drain in place. As the medical operator attempts to withdraw the sheath from the drain and the patient's body, in the event that a suture has inadvertently passed through the body of the surgical drain, such inadvertently placed suture will obstruct the removal of the sheath, in turn alerting the medical operator that the surgical drain has been inadvertently sutured and allowing them to correct the drain placement during the same surgical procedure.
FILED	Wednesday, March 18, 2015
APPL NO	15/127082
ART UNIT	3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0668 (20130101) A61M 27/00 (20130101) Original (OR) Class A61M 2025/0286 (20130101) A61M 2025/0681 (20130101) A61M 2205/04 (20130101) A61M 2205/60 (20130101)
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10287227 — Myricanol derivatives and uses thereof for treatment of neurodegenerative diseases

US 10287227	Dickey et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	University of South Florida (Tampa, Florida); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S)	UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); The Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Chad Dickey (Tampa, Florida); Umesh Jinwal (Tampa, Florida); Laurent Calcul (Tampa, Florida); Bill J. Baker (Tampa, Florida); Matthew Lebar (Boston, Massachusetts)
ABSTRACT	The subject invention pertains to myricanol derivatives, therapeutic compositions, and methods for treatment of neurodegenerative diseases, in particular, neurodegenerative diseases associated with abnormal accumulation of protein tau.
FILED	Tuesday, January 24, 2017
APPL NO	15/414242
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/11 (20130101) A61K 31/121 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 43/21 (20130101) C07C 43/23 (20130101) Original (OR) Class C07C 43/215 (20130101) C07C 47/277 (20130101) C07C 69/28 (20130101) C07C 2603/38 (20170501) C07C 2603/40 (20170501)
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10289650 — Active stability devices and systems for mobile devices

US 10289650	Pearlman et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburg, Pennsylvania); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Jonathan L. Pearlman (Pittsburgh, Pennsylvania); Jonathan Aaron Duvall (Pittsburgh, Pennsylvania); Benjamin Todd Gebrosky (Gibsonia, Pennsylvania); Rory Alan Cooper (Gibsonia, Pennsylvania)
ABSTRACT	A system for use with a mobile device includes at least one sensor to sense a variable related to tilting of the mobile device and at least one activatable system in operative connection with the sensor. The at least one activatable system increases stability of the mobile device upon actuation/change in state thereof on the basis of data measured by the at least one sensor. A variable related to tilting includes variables that indicate concurrent, actual tilting as described herein as well as variables predictive of imminent tilting. Activatable systems hereof change state upon actuation or activation to increase stability of the mobile device by reducing, eliminating or preventing tilting.
FILED	Thursday, September 22, 2016
APPL NO	15/273116
ART UNIT	3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/00 (20130101) A61G 5/043 (20130101) A61G 5/063 (20130101) A61G 5/068 (20130101) A61G 5/128 (20161101) A61G 5/1054 (20161101) A61G 5/1089 (20161101) A61G 2203/14 (20130101) A61G 2203/42 (20130101) Electric Digital Data Processing G06F 17/00 (20130101) Original (OR) Class
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Department of Agriculture (USDA)

10285411 — System for cleaning fresh and fresh-cut produce

US 10285411	Luo et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia); The Board of Trustees of The University of Illinois (Urbana, Illinois)
INVENTOR(S)	Yaguang Luo (Bethesda, Maryland); Bin Zhou (Laurel, Maryland); Patricia D. Millner (Burtonsville, Maryland); Arne J. Pearlstein (Urbana, Illinois)
ABSTRACT	The system for cleaning fresh and freshly-cut produce is designed to clean produce as soon as practicable after the produce is cut. As the produce falls downwardly, a spray manifold directs a produce-washing liquid upwardly so that the produce-washing liquid directly sprays and impacts the falling produce. The impact of the produce-washing liquid causes the produce to tumble and the descent of the produce is slowed, and consequently the produce is thoroughly coated and cleaned by the produce-washing liquid. In an alternative embodiment, a suspending fluid (preferably air) is simultaneously directed to the falling produce to slow the descent of the produce and further ensure that the produce is thoroughly washed and directly sprayed by the produce-washing liquid.
FILED	Friday, January 27, 2017
APPL NO	15/417570
ART UNIT	1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 7/16 (20130101) A23B 7/144 (20130101) Original (OR) Class A23B 7/157 (20130101) A23B 7/158 (20130101) Machines or Apparatus for Treating Harvested Fruit, Vegetables or Flower Bulbs in Bulk, Not Otherwise Provided For; Peeling Vegetables or Fruit in Bulk; Apparatus for Preparing Animal Feeding- Stuffs A23N 12/02 (20130101) A23N 12/06 (20130101)
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10286054 — Attenuated EHEC and clostridial toxins TcdA and TcdB based vaccine for Clostridium difficil associated disease (CDAD)

US 10286054	Boedeker et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Agriculture (USDA)
APPLICANT(S)	DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S)	Edgar C. Boedeker (Washington, District of Columbia); Sudeep Kumar (Washington, District of Columbia)
ABSTRACT	Provided are novel methods for expressing antigens in a vaccine vector strain, a live oral vaccine designed to prevent clostridium difficile-associated disease and methods for delivering antigens to the mucosal immune system of a subject.
FILED	Friday, October 11, 2013
APPL NO	14/435443
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/08 (20130101) Original (OR) Class A61K 2039/522 (20130101) A61K 2039/523 (20130101) A61K 2039/541 (20130101) Peptides C07K 14/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101)
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10287600 — Compositions and methods for differential regulation of fatty acid unsaturation in membrane lipids and seed oil

US 10287600	Browse et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Washington State University (Pullman, Washington)
ASSIGNEE(S)	Washington State University (Pullman, Washington)
INVENTOR(S)	John A. Browse (Palouse, Washington); Chaofu Lu (Bozeman, Montana); Zhanguo Xin (Lubbock, Texas)
ABSTRACT	Aspects of the invention provide methods for differential regulation of fatty acid unsaturation in seed oil and membrane lipids of plants based on modulation of a previously unknown biosynthetic pathway involving a novel phosphatidylcholine:diacylglycerol cholinephosphotransferase (PDCT) that regulates phosphatidylcholine biosynthesis in developing oil seed plants. Specific aspects relate to inventive PDCT polypeptides including, for example, variants, deletions, muteins, fusion proteins, and orthologs thereof (collectively PDCT proteins), to nucleic acids encoding same, to plants comprising such PDCT sequences or proteins or devoid or depleted of such PDCT proteins or sequences, and to methods for generating plants having altered or no PDCT expression and/or activity, including but not limited to methods comprising mutagenesis, recombinant DNA, transgenics, etc.
FILED	Friday, November 20, 2015
APPL NO	14/948166
ART UNIT	1663 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 5/10 (20130101) Edible Oils or Fats, e.g Margarines, Shortenings, Cooking Oils A23D 9/013 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/026 (20130101) C10L 2200/0476 (20130101) C10L 2270/026 (20130101) Producing, e.g by Pressing Raw Materials or by Extraction From Waste Materials, Refining or Preserving Fats, Fatty Substances, e.g Lanolin, Fatty Oils or Waxes; Essential Oils; Perfumes C11B 1/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1288 (20130101) C12N 15/8247 (20130101) Original (OR) Class Enzymes C12Y 207/08002 (20130101)
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10287611 — Engineering the pathway for succinate production

US 10287611	Zhang et al.
FUNDED BY	Department of Energy (DOE) Department of Agriculture (USDA)
APPLICANT(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S)	Xueli Zhang (Tianjin, China PRC); Kaemwich Jantama (Chiang Mai, Thailand); Jonathan C. Moore (Encinitas, California); Laura R. Jarboe (Ames, Iowa); Keelnatham T. Shanmugam (Gainesville, Florida); Lonnie O'Neal Ingram (Gainesville, Florida)
ABSTRACT	This invention relates to biocatalysts for the efficient production of succinic acid and/or other products from renewable biological feedstocks. The biocatalysts have a very high efficiency for the growth-coupled production of succinic acid and/or other products from carbohydrate feed stocks as a result of both genetic manipulation and metabolic evolution. More specifically, certain biocatalysts of the present invention produce succinic acid at high titers and yields in mineral salts media during simple pH-controlled batch fermentation without the addition of any exogenous genetic material. The genetic manipulations of the present invention are concerned with energy-conserving strategies coupled with the elimination of alternative routes for NADH oxidation other than the routes for succinic acid production. The biocatalysts contain glucose-repressed gluconeogenic phosphoenolpyruvate carboxykinase (pck) derepressed by genetic modifications and a genetically-inactivated phosphotransferase system. In terms of succinic acid production efficiency, the biocatalysts of the present invention are functionally equivalent to succinate producing rumen bacteria such as Actinobacillus succinogens and Mannheimia succiniproducens, with one difference: that the biocatalysts are able to achieve this high level of succinic acid production in a minimal salt medium with carbohydrate source, as opposed to the requirement for a rich medium for succinic acid production by rumen bacteria.
FILED	Wednesday, May 06, 2015
APPL NO	14/705011
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 9/93 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/46 (20130101) Original (OR) Class Enzymes C12Y 401/01 (20130101) C12Y 604/01001 (20130101)
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10288625 — Early determination of pregnancy status in ruminants

US 10288625	Hansen et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Colorado State University Research Foundation (Fort Collins, Colorado)
ASSIGNEE(S)	Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S)	Thomas R. Hansen (Fort Collins, Colorado); Jessica Prenni (Fort Collins, Colorado); Torrance M. Nett (Bellvue, Colorado); Kevin McSweeney (Loveland, Colorado); Jared Romero (Alamosa, Colorado)
ABSTRACT	The present invention provides compositions and methods for detection schemes for ascertaining pregnancy status of an animal. The compositions and methods employ interferon-tau (IFNT) and/or antibodies specific for IFNT. Methods of the present invention detect the presence of IFNT in samples obtained from animals as an early indicator of pregnancy. Methods are provided to identify non-pregnant animals so that management decisions regarding rebreeding can be made earlier compared to existing approaches.
FILED	Monday, February 26, 2018
APPL NO	15/904684
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 29/005 (20130101) A01K 67/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/689 (20130101) Original (OR) Class G01N 33/6866 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/26 (20130101) H01J 49/0027 (20130101)
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National Aeronautics and Space Administration (NASA)

10287024 — Direct drive aft fan engine

US 10287024	Suciu et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Neil A Armstrong Flight Research Center (AFRC)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Gabriel L. Suciu (Glastonbury, Connecticut); Jesse M. Chandler (South Windsor, Connecticut)
ABSTRACT	An aircraft engine includes a gas generator, a turbine fluidly connected to the gas generator, and a fan connected to the turbine via a shaft. The fan is positioned aft of the turbine, and the shaft is at least partially disposed in a fan inlet flowpath.
FILED	Thursday, August 04, 2016
APPL NO	15/228359
ART UNIT	3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/14 (20130101) Original (OR) Class B64D 33/04 (20130101) B64D 2033/0226 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 9/02 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/10 (20130101) Jet-propulsion Plants F02K 3/062 (20130101) Non-positive-displacement Pumps F04D 29/321 (20130101) F04D 29/325 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/60 (20130101)
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10288009 — Efficient, low pressure ratio propulsor for gas turbine engines

US 10288009	Gallagher et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Edward J. Gallagher (West Hartford, Connecticut); Byron R. Monzon (Cromwell, Connecticut)
ABSTRACT	A gas turbine engine includes a bypass flow passage that has an inlet and defines a bypass ratio in a range of approximately 8.5 to 13.5. A fan is arranged at the inlet. A first turbine is coupled with a first shaft such that rotation of the first turbine will drive the fan. A first compressor is coupled with the first shaft and includes three stages, and a second turbine is coupled with a second shaft and includes two stages. The fan includes a row of 16 (N) fan blades that has a solidity value (R) that is from 1.0 to 1.2 and a ratio of N/R that is from 13.3 to 16.0.
FILED	Wednesday, August 31, 2016
APPL NO	15/252689
ART UNIT	3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/14 (20130101) Jet-propulsion Plants F02K 1/06 (20130101) F02K 3/06 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/327 (20130101) F05D 2260/4031 (20130101)
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10288110 — Washer for retaining assembly pin

US 10288110	Zaffetti
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Hamilton Sundstrand Space Systems International, Inc. (Windsor Locks, Connecticut)
ASSIGNEE(S)	HAMILTON SUNDSTRAND SPACE SYSTEMS INTERNATIONAL, INC. (Windsor Locks, Connecticut)
INVENTOR(S)	Mark A. Zaffetti (Suffield, Connecticut)
ABSTRACT	An assembly includes a first structure having a first pin aperture and at least one first fastener aperture adjacent the first pin aperture and a second structure to attached to the first structure having a second pin aperture and at least one second fastener aperture adjacent the second pin aperture. At least one fastener is configured to pass through the first and second fastener apertures and attach the first structure to the second structure. An assembly pin passes through the first and second pin apertures and is trapped within the first and second pin apertures. A pin-securing washer having a fastener surface defining at least one fastener aperture and a pin-securing surface to secure the assembly pin within the pin apertures. The at least one fastener passes through the at least one fastener aperture of the pin-securing washer.
FILED	Wednesday, May 20, 2015
APPL NO	14/717583
ART UNIT	3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 41/002 (20130101) F16B 43/00 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 403/75 (20150115)
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10291150 — Method and system for operating a phase-leg of a three-level active neutral point clamped converter

US 10291150	Zhang et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Glenn Research Center (GLENN)
APPLICANT(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
ASSIGNEE(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S)	Di Zhang (Niskayuna, New York); Jiangbiao He (Niskayuna, New York); Sachin Madhusoodhanan (San Jose, California); Di Pan (Niskayuna, New York)
ABSTRACT	A method for operating a phase-leg of a three-level active neutral point clamped (3L-ANPC) converter is presented. The phase-leg includes an output terminal, a plurality of input terminals, and a plurality of switches disposed therebetween. The method includes operating the phase-leg in a neutral state to generate an output voltage having a neutral level. The method further includes transitioning the phase-leg to a first intermediate neutral state from the neutral state. Moreover, the method includes transitioning the phase-leg from the first intermediate neutral state to a first state to generate the output voltage having a first level. A modulator for operating the phase-leg of the 3L-ANPC converter is also presented. Moreover, a 3L-ANPC converter including the modulator is presented.
FILED	Wednesday, November 08, 2017
APPL NO	15/806352
ART UNIT	2838 — Electrical Circuits and Systems
CURRENT CPC	Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/487 (20130101) H02M 7/5395 (20130101) Original (OR) Class
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Department of Homeland Security (DHS)

10289819 — Active authentication of users

US 10289819	Stavrou et al.
FUNDED BY	Department of Homeland Security (DHS) Science and Technology Directorate (DHS-ST) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Kryptowire LLC (Fairfax, Virginia)
ASSIGNEE(S)	KRYPTOWIRE LLC (Fairfax, Virginia)
INVENTOR(S)	Angelos Stavrou (Fairfax, Virginia); Rahul Murmuria (Burke, Virginia); Ryan Johnson (Warrenton, Virginia); Daniel Barbara (Reston, Virginia)
ABSTRACT	Embodiments herein disclose a method and system for actively authenticating users of an electronic device in a continuous manner using a plurality of factors comprising of biometric modalities, power consumption, application usage, user interactions, user movement, and user location/travel.
FILED	Friday, August 12, 2016
APPL NO	15/236049
ART UNIT	2434 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/32 (20130101) G06F 21/316 (20130101) Original (OR) Class
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10290483 — Systems and methods for transfer of ions for analysis

US 10290483	Ouyang et al.
FUNDED BY	Department of Homeland Security (DHS) Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Zheng Ouyang (West Lafayette, Indiana); Robert Graham Cooks (West Lafayette, Indiana); Sandilya Venkata Garimella (West Lafayette, Indiana); Jason David Harper (Lafayette, Indiana); Nicholas Alan Charipar (Batavia, Indiana)
ABSTRACT	The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.
FILED	Thursday, May 24, 2018
APPL NO	15/988698
ART UNIT	2881 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/04 (20130101) H01J 49/10 (20130101) H01J 49/26 (20130101) H01J 49/0027 (20130101) H01J 49/0031 (20130101) H01J 49/40 (20130101) H01J 49/0404 (20130101) Original (OR) Class H01J 49/0409 (20130101) H01J 49/0422 (20130101) H01J 49/0459 (20130101) H01J 49/4215 (20130101)
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Small Business Administration (SBA)

10285943 — Aptamer bioconjugate drug delivery device

US 10285943	Bloembergen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Steven Bloembergen (Okemos, Michigan); Ian J. McLennan (Burlington, Canada); Nathan Jones (Hamilton, Canada); Ryan Wagner (Kitchener, Canada); Aareet Krsna Ganesh Shermon (Waterloo, Canada); Abdel Rahman Elsayed (Waterloo, Canada); Juewen Liu (Kitchener, Canada)
ASSIGNEE(S)	GreenMark Biomedical Inc. (East Lansing, Michigan)
INVENTOR(S)	Steven Bloembergen (Okemos, Michigan); Ian J. McLennan (Burlington, Canada); Nathan Jones (Hamilton, Canada); Ryan Wagner (Kitchener, Canada); Aareet Krsna Ganesh Shermon (Waterloo, Canada); Abdel Rahman Elsayed (Waterloo, Canada); Juewen Liu (Kitchener, Canada)
ABSTRACT	A delivery device for an active agent comprises nanoparticles based on a biopolymer such as starch. The delivery device may also be in the form of an aptamer-biopolymer-active agent conjugate wherein the aptamer targets the device for the treatment of specific disorders. The nanoparticles may be made by applying a high shear force in the presence of a crosslinker. The particles may be predominantly in the range of 50-150 nm and form a colloidal dispersion of crosslinked hydrogel particles in water. The biopolymer may be functionalized. The aptamer may be conjugated directly to the cross-linked biopolymers. The active agent may be a drug useful for the treatment of cancer. The delivery device survives for a period of time in the body sufficient to allow for the sustained release of a drug and for the transportation and uptake of the conjugate into targeted cells. However, the biopolymer is biocompatible and resorbable.
FILED	Friday, December 02, 2011
APPL NO	13/990278
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/145 (20130101) Original (OR) Class A61K 9/1676 (20130101) A61K 9/5161 (20130101) A61K 31/704 (20130101) A61K 47/36 (20130101) A61K 47/549 (20170801) A61K 47/6939 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Polysaccharides; Derivatives Thereof C08B 31/003 (20130101) C08B 31/185 (20130101) C08B 33/00 (20130101) C08B 35/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/906 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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10287573 — Combinatorial DNA taggants and methods of preparation and use thereof

US 10287573	Macula
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Research Laboratory (AFRL) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	JEANSEE LLC (Geneseo, New York)
ASSIGNEE(S)	JEANSEE LLC (Geneseo, New York)
INVENTOR(S)	Anthony J. Macula (Geneseo, New York)
ABSTRACT	DNA taggants in which the nucleotide sequences are defined according to combinatorial mathematical principles. Methods of defining nucleotide sequences of the combinatorial DNA taggants, and using such taggants for authentication and tracking and tracing an object or process are also disclosed.
FILED	Monday, April 14, 2014
APPL NO	14/251690
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6876 (20130101) C12Q 2563/185 (20130101)
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Environmental Protection Agency (EPA)

10290089 — Cyanobacteria assessment network

US 10290089	Schaeffer et al.
FUNDED BY	Environmental Protection Agency (EPA)
APPLICANT(S)	The United States of America, as represented by the Administrator of the U.S. Environmental Protection (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE ADMINISTRATOR OF THE U.S. ENVIRONMENTAL PROTECTION AGENCY (Washington, District of Columbia)
INVENTOR(S)	Blake Allen Schaeffer (Cary, North Carolina); Robyn Nicole Conmy (Cincinnati, Ohio); Darryl Joel Keith (Wakefield, Rhode Island); Ross S. Lunetta (Cary, North Carolina); Mark S. Murphy (Apex, North Carolina); Torrin Hultgren (Seattle, Washington)
ABSTRACT	Systems and methods are used to determine the location and severity of harmful algal blooms or other water quality parameters. GPS location information is transmitted from a mobile device and recent Satellite image data and water quality parameters are provided to the mobile device. Data regarding other locations, historical water quality parameters and algorithm based predictive results are provided for the end user. This provides for near-real time information allowing users to make decisions regarding fishing, beach closures, municipal water intake, etc. so as to avoid toxic effects of a harmful algal bloom.
FILED	Friday, May 22, 2015
APPL NO	14/545574
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Electric Digital Data Processing G06F 16/9537 (20190101) Image Data Processing or Generation, in General G06T 7/0004 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) Wireless Communication Networks H04W 4/02 (20130101) Technologies for Adaptation to Climate Change Y02A 20/16 (20180101)
VIEW PATENT	@ USPTO: Full Text PDF

U.S. State Government

10290871 — Battery cell engineering and design to reach high energy

US 10290871	Masarapu et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) U.S. State Government State of California California Energy Commission (CEC)
APPLICANT(S)	Envia Systems, Inc. (Newark, California)
ASSIGNEE(S)	Zenlabs Energy, Inc. (Fremont, California)
INVENTOR(S)	Charan Masarapu (Fremont, California); Haixia Deng (Fremont, California); Yongbong Han (San Francisco, California); Yogesh Kumar Anguchamy (Newark, California); Subramanian Venkatachalam (Pleasanton, California); Sujeet Kumar (Newark, California); Herman A. Lopez (Sunnyvale, California)
ABSTRACT	Improved high energy capacity designs for lithium ion batteries are described that take advantage of the properties of high specific capacity anode active compositions and high specific capacity cathode active compositions. In particular, specific electrode designs provide for achieving very high energy densities. Furthermore, the complex behavior of the active materials is used advantageously in a radical electrode balancing design that significantly reduced wasted electrode capacity in either electrode when cycling under realistic conditions of moderate to high discharge rates and/or over a reduced depth of discharge.
FILED	Wednesday, June 24, 2015
APPL NO	14/749099
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/024 (20130101) H01M 2/1646 (20130101) H01M 4/38 (20130101) H01M 4/131 (20130101) H01M 4/134 (20130101) H01M 4/386 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/582 (20130101) Original (OR) Class H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 10/446 (20130101) H01M 10/0525 (20130101) H01M 2220/20 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

United States Postal Service (USPS)

10287107 — System and method of article feeder operation

US 10287107	Brown et al.
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S)	United States Postal Service (Washington, District of Columbia)
INVENTOR(S)	John W. Brown (Manassas, Virginia); Edward F. Houston (Bristow, Virginia); Juan A. Roman (Fairfax, Virginia); Leung M. Shiu (Gaithersburg, Maryland); Riley H. Mayhall (Germantown, Maryland); Thomas A. Hillerich, Jr. (Louisville, Kentucky); Jacob L. Timm (Pasadena, Maryland); Matthew G. Good (Eldersburg, Maryland); William P. McConnell (Woodstock, Maryland); Robert L. Schlender (Columbia, Maryland); Christopher D. Austin (Parkville, Maryland)
ABSTRACT	Embodiments of a system and method for shingulating, singulating, and synchronizing articles in an article feeder system are disclosed. The article feeder system may include a shingulating device configured to receive a stack of articles and to produce a positively lapped stack of articles, a plurality of picking devices configured to pick one or more articles from the positively lapped stack of articles and to produce one or more singulated articles, and one or more synchronization devices configured to deliver the one or more singulated articles to one or more sorter windows.
FILED	Wednesday, June 17, 2015
APPL NO	14/742480
ART UNIT	3653 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 47/06 (20130101) B65G 47/28 (20130101) B65G 47/46 (20130101) B65G 47/74 (20130101) Original (OR) Class B65G 59/04 (20130101) Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables B65H 3/46 (20130101) B65H 3/124 (20130101) B65H 5/24 (20130101) B65H 5/224 (20130101) B65H 7/12 (20130101) B65H 2220/09 (20130101) B65H 2220/09 (20130101) B65H 2301/321 (20130101) B65H 2404/2691 (20130101) B65H 2406/32 (20130101) B65H 2406/32 (20130101) B65H 2701/1916 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

10287009 — Helicopter blade folding apparatus

US 10287009	Peterson et al.
FUNDED BY
APPLICANT(S)	Alion Science and Technology Corporation (McLean, Virginia)
ASSIGNEE(S)	ALION SCIENCE AND TECHNOLOGY CORPORATION (McLean, Virginia)
INVENTOR(S)	Eric Peterson (St. Croix Falls, Wisconsin); Jeremiah Schweitzer (Grantsburg, Wisconsin); Zachary Anderson (Grantsburg, Wisconsin)
ABSTRACT	The present invention relates to a blade folding apparatus that may incorporate an overhead blade lifting system that reduces binding loads on blade pins induced by blade weight and pitch, and a folding mechanism that removes the necessity of personnel with external guide-poles to rotate main rotor blades. The apparatus may include flap locks, an overhead lifting system support structure attached to the flap locks, and two blade support beams to create and support a lifting point near each blade's longitudinal and lateral center of gravity. The blade support beams may be fitted with an articulation mechanism that lifts and/or lowers the overhead lifting structure. The apparatus facilitates rapid folding of the main rotor blades, and, when used with blade clamping mechanisms, is capable of aiding in the removal and/or the re-installation of the main rotor blades without external lifting mechanisms.
FILED	Wednesday, May 18, 2016
APPL NO	15/158180
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Aeroplanes; Helicopters B64C 27/50 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10288715 — Systems and methods for direction finding using augmented spatial sample covariance matrices

US 10288715	Bowden
FUNDED BY
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	James M. Bowden (Forney, Texas)
ABSTRACT	In an array antenna having a plurality of subarrays, a direction finding system and technique includes receiving signals at an array antenna and capturing data with a plurality of groups of subarrays. Each group of subarrays may capture data during a selected one of a plurality of different dwell times. The method further includes generating a plurality of dwell spatial sample covariance matrices (SCMs) using data corresponding to one or more of the plurality of groups of subarrays and combining the plurality of dwell spatial SCMs in complex form to generate an aggregate covariance matrix (ACM). The ACM may then be used in subsequent processing with MINDIST technique to estimate a direction of a received signal based on the combined data.
FILED	Friday, September 09, 2016
APPL NO	15/260715
ART UNIT	3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/14 (20130101) G01S 3/043 (20130101) Original (OR) Class G01S 3/48 (20130101) G01S 3/74 (20130101) G01S 11/02 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10288716 — Systems and methods for direction finding based on minimum distance search to principal components

US 10288716	Bowden
FUNDED BY
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	James M. Bowden (Forney, Texas)
ABSTRACT	The concepts, systems and method described herein provide direction finding (DF) methods based on a minimum distance (MINDIST) search to principal components. In an embodiment, the method includes capturing samples of data from one or more array elements. The samples may be samples of a signal received at the array elements. The method includes generating a spatial sample covariance matrix (SCM) using the samples of data, extracting principal components from the SCM and generating a principal component table using angle and frequency measurement for each of the principal components. The method further includes determining a distance between a test point and each value in the principal component table and identifying a minimum distance point corresponding to a direction of the received signal. The minimum distance point may correspond to direction of arrival of a signal on the one or more array elements.
FILED	Friday, September 09, 2016
APPL NO	15/260508
ART UNIT	3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/48 (20130101) Original (OR) Class G01S 3/465 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10290676 — Superconducting device with thermally conductive heat sink

US 10290676	Pesetski et al.
FUNDED BY
APPLICANT(S)	Aaron A. Pesetski (Gambrills, Maryland); Patrick Alan Loney (Fairview Park, Ohio)
ASSIGNEE(S)	NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S)	Aaron A. Pesetski (Gambrills, Maryland); Patrick Alan Loney (Fairview Park, Ohio)
ABSTRACT	An integrated circuit is provided that comprises a resistor, a first superconducting structure coupled to a first end of the resistor, and a second superconducting structure coupled to a second end of the resistor. A thermally conductive heat sink structure is coupled to the second end of the resistor for moving hot electrons from the resistor prior to the electrons generating phonons.
FILED	Tuesday, August 15, 2017
APPL NO	15/677756
ART UNIT	2896 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) H01L 23/367 (20130101) H01L 27/18 (20130101) Original (OR) Class H01L 39/045 (20130101) H01L 2223/6683 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

What You'll Find On This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, May 14, 2019.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190514.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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