FedInvent™ Patents

Patent Details for Tuesday, May 28, 2019 

This page was updated on Monday, March 27, 2023 at 05:48 AM GMT

Department of Defense (DOD) 

US 10299695 Muraskin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Jordan Muraskin (New York, New York);  Jason Sherwin (New York, New York);  Paul Sajda (New York, New York)
ABSTRACT Methods and systems for evaluating a subject's response to a task related to a stimulus include a brain activity sensor, such as an EEG sensor, for measuring neural data generated by the subject in response to the visual stimulus. One or more neural discriminators can be calculated based on the neural data. In order to generate one or more neural discriminators, two or more task conditions can be selected for discrimination. The subject's performance can be evaluated based on the one or more neural discriminators. Feedback can be provided to the subject to assist in achieving better performance.
FILED Monday, February 02, 2015
APPL NO 14/612233
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/0059 (20130101)
A61B 5/0075 (20130101)
A61B 5/0478 (20130101)
A61B 5/0482 (20130101)
A61B 5/742 (20130101)
A61B 5/04012 (20130101)
A61B 5/04842 (20130101) Original (OR) Class
A61B 2503/10 (20130101)
A61B 2576/026 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4806 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10299779 Shepherd et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Robert F. Shepherd (Brooktondale, New York);  George M. Whitesides (Newton, Massachusetts);  Bobak Mosadegh (New York, New York)
ABSTRACT A surgical device for displacement of organs within a body cavity for providing at least visual access to a selected site includes an expandable bladder, wherein the elasticity of the bladder varies across the surface of the bladder, said variation in elasticity selected to provide a predetermined, non-spherical shape when expanded; and a valve on the proximal end on the inflatable bladder for introduction of a pressurizing gas into the soft bladder.
FILED Monday, October 20, 2014
APPL NO 14/518433
ART UNIT 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/32 (20130101)
A61B 1/00082 (20130101)
A61B 1/3132 (20130101)
A61B 17/0218 (20130101) Original (OR) Class
A61B 2017/0225 (20130101)
A61B 2017/00557 (20130101)
A61B 2017/00831 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10299941 Langenfeld et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Research, Development and Engineering Command (RDECOM)
APPLICANT(S) DEKA Products Limited Partnership (Manchester, New Hampshire)
ASSIGNEE(S) DEKA PRODUCTS LIMITED PARTNERSHIP (Manchester, New Hampshire)
INVENTOR(S) Christopher C. Langenfeld (Nashua, New Hampshire);  Christopher O. Evans (Amherst, New Hampshire);  Stanley B. Smith, III (Raymond, New Hampshire);  Alexander H. Muller (Manchester, New Hampshire);  John M. Kerwin (Manchester, New Hampshire);  Thomas S. Schnellinger (North Andover, Massachusetts);  G. Michael Guay (Greenville, New Hampshire);  Dirk A. van der Merwe (Manchester, New Hampshire)
ABSTRACT A prosthetic arm apparatus comprising a plurality of interconnected segments that provide the prosthetic arm apparatus with substantially the same movement capability and function as a human arm. The segments are connected to one another and connectable to a harness mount that may be adorned by the user. Each segment of the plurality of segments includes an actuator providing a portion of the movement capability, and each segment may operate independently of each of the other segments of the plurality of segments. One segment of the plurality of segments includes a non-backdriving clutch that transfers power from the actuator to an output interface of the segment when the actuator is actuated to generate movement of the output interface in either of two opposing directions and prevents backward transfer of power from the output interface to the actuator of the segment in both of the two opposing directions.
FILED Monday, July 27, 2015
APPL NO 14/809624
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/54 (20130101) Original (OR) Class
A61F 2/68 (20130101)
A61F 2/78 (20130101)
A61F 2/581 (20130101)
A61F 2/582 (20130101)
A61F 2/585 (20130101)
A61F 2/586 (20130101)
A61F 2002/507 (20130101)
A61F 2002/543 (20130101)
A61F 2002/546 (20130101)
A61F 2002/587 (20130101)
A61F 2002/701 (20130101)
A61F 2002/704 (20130101)
A61F 2002/764 (20130101)
A61F 2002/5061 (20130101)
A61F 2002/5069 (20130101)
A61F 2002/5083 (20130101)
A61F 2002/6827 (20130101)
A61F 2002/6836 (20130101)
A61F 2002/6845 (20130101)
A61F 2002/6854 (20130101)
A61F 2002/6863 (20130101)
A61F 2002/7625 (20130101)
A61F 2002/7635 (20130101)
A61F 2002/7862 (20130101)
A61F 2002/30464 (20130101)
A61F 2220/0075 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300029 Mangino
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia)
ASSIGNEE(S) Virginia Commonwealth University (Richmond, Virginia)
INVENTOR(S) Martin Mangino (Powhatan, Virginia)
ABSTRACT An organ protectant solution which is intravenously administered includes at least one oncotic agent and optionally a high concentration of cell-impermeant molecules. Together, they promote transfer of water from cells to interstitium and into the capillaries, thereby preventing or reducing cell swelling, maintaining blood circulation and oxygenation of tissues, and extending the “Golden Hour” for traumatic and/or hemorrhagic shock patients. In addition, compositions comprising PEG-20k and methods of their use for preserving and/or reanimating harvested organs ex vivo for lengthy periods of time (e.g. at least about 8-24 hours) are also provided.
FILED Friday, October 14, 2016
APPL NO 15/293689
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0221 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/08 (20130101)
A61K 31/191 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300070 Goldman et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Aaron Goldman (Somerville, Massachusetts);  Shiladitya Sengupta (Waltham, Massachusetts);  Abhimanyu Paraskar (Belmont, Massachusetts)
ABSTRACT Described are combination therapies and metabolically-activated drug conjugates and their use in treating cancer in subjects.
FILED Friday, March 27, 2015
APPL NO 15/127973
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/704 (20130101)
A61K 31/704 (20130101)
A61K 31/5377 (20130101) Original (OR) Class
A61K 31/5377 (20130101)
A61K 31/7068 (20130101)
A61K 31/7068 (20130101)
A61K 45/06 (20130101)
A61K 47/55 (20170801)
A61K 47/556 (20170801)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300073 Haudenschild et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Dominik Haudenschild (Davis, California);  Jasper Yik (Elk Grove, California)
ABSTRACT Provided are methods for the combined use of cyclin-dependent kinase 9 (CDK9) inhibitors and bromodomain containing 4 (BRD4) inhibitors to reduce, inhibit and/or prevent cartilage degradation and systemic traumatic inflammation. A combination of CDK9 inhibitors and BRD4 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. A combination of CDK9 inhibitors and BRD4 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
FILED Tuesday, October 13, 2015
APPL NO 15/517476
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/352 (20130101)
A61K 31/352 (20130101)
A61K 31/445 (20130101)
A61K 31/551 (20130101)
A61K 31/551 (20130101)
A61K 31/5513 (20130101) Original (OR) Class
A61K 31/5513 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300076 Szmulewitz et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Russell Z. Szmulewitz (Chicago, Illinois);  Suzanne D. Conzen (Park Ridge, Illinois)
ABSTRACT Methods are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer may be one that has become resistant to androgen deprivation therapy, for example, by increase in glucocorticoid receptor expression and/or activity.
FILED Thursday, September 14, 2017
APPL NO 15/704726
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/437 (20130101)
A61K 31/437 (20130101)
A61K 31/567 (20130101) Original (OR) Class
A61K 31/567 (20130101)
A61K 31/569 (20130101)
A61K 31/569 (20130101)
A61K 31/573 (20130101)
A61K 31/573 (20130101)
A61K 31/4166 (20130101)
A61K 31/4166 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300143 Sengupta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Shiladitya Sengupta (Waltham, Massachusetts);  Ashish Kulkarni (Waltham, Massachusetts);  Poornima Rao (Waltham, Massachusetts);  Bhaskar Roy (Belmont, Massachusetts)
ABSTRACT Described herein are compositions and methods relating to chemotherapeutic agent conjugates and the treatment of cancer.
FILED Monday, October 02, 2017
APPL NO 15/722831
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)
A61K 47/55 (20170801) Original (OR) Class
A61K 47/554 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300309 Maharbiz et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michel M. Maharbiz (El Cerrito, California);  Jose M. Carmena (Berkeley, California);  Mekhail Anwar (San Francisco, California);  Burak A. Ozilgen (Berkeley, California);  Dongjin Seo (Albany, California);  Federica Fava (Berkeley, California)
ABSTRACT Described herein is an implantable device having a sensor configured to detect an amount of an analyte, a pH, a temperature, strain, or a pressure; and an ultrasonic transducer with a length of about 5 mm or less in the longest dimension, configured to receive current modulated based on the analyte amount, the pH, the temperature, or the pressure detected by the sensor, and emit an ultrasonic backscatter based on the received current. The implantable device can be implanted in a subject, such as an animal or a plant. Also described herein are systems including one or more implantable devices and an interrogator comprising one or more ultrasonic transducers configured to transmit ultrasonic waves to the one or more implantable devices or receive ultrasonic backscatter from the one or more implantable devices. Also described are methods of detecting an amount of an analyte, a pH, a temperature, a strain, or a pressure.
FILED Tuesday, September 25, 2018
APPL NO 16/141902
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0031 (20130101)
A61B 5/076 (20130101)
A61B 5/686 (20130101)
A61B 5/4836 (20130101)
A61B 6/4258 (20130101)
A61B 8/48 (20130101)
A61B 8/085 (20130101)
A61B 8/0808 (20130101)
A61B 8/0875 (20130101)
A61B 2505/05 (20130101)
A61B 2560/0219 (20130101)
A61B 2562/12 (20130101)
A61B 2562/028 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 39/0208 (20130101)
A61M 2205/04 (20130101)
A61M 2205/825 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0534 (20130101)
A61N 1/3605 (20130101)
A61N 1/3787 (20130101)
A61N 1/37205 (20130101)
A61N 5/1071 (20130101)
A61N 7/02 (20130101) Original (OR) Class
A61N 2005/1087 (20130101)
A61N 2007/0021 (20130101)

Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/327 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/025 (20130101)
H02J 50/15 (20160201)
H02J 50/90 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300310 Maharbiz et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michel M. Maharbiz (El Cerrito, California);  Jose M. Carmena (Berkeley, California);  Mekhail Anwar (San Francisco, California);  Burak A. Ozilgen (Berkeley, California);  Dongjin Seo (Albany, New York);  Federica Fava (Berkeley, California)
ABSTRACT Described herein is an implantable device having a sensor configured to detect an amount of an analyte, a pH, a temperature, strain, or a pressure; and an ultrasonic transducer with a length of about 5 mm or less in the longest dimension, configured to receive current modulated based on the analyte amount, the pH, the temperature, or the pressure detected by the sensor, and emit an ultrasonic backscatter based on the received current. The implantable device can be implanted in a subject, such as an animal or a plant. Also described herein are systems including one or more implantable devices and an interrogator comprising one or more ultrasonic transducers configured to transmit ultrasonic waves to the one or more implantable devices or receive ultrasonic backscatter from the one or more implantable devices. Also described are methods of detecting an amount of an analyte, a pH, a temperature, a strain, or a pressure.
FILED Tuesday, September 25, 2018
APPL NO 16/141930
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0031 (20130101)
A61B 5/076 (20130101)
A61B 5/686 (20130101)
A61B 5/4836 (20130101)
A61B 6/4258 (20130101)
A61B 8/48 (20130101)
A61B 8/085 (20130101)
A61B 8/0808 (20130101)
A61B 8/0875 (20130101)
A61B 2505/05 (20130101)
A61B 2560/0219 (20130101)
A61B 2562/12 (20130101)
A61B 2562/028 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 39/0208 (20130101)
A61M 2205/04 (20130101)
A61M 2205/825 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0534 (20130101)
A61N 1/3605 (20130101)
A61N 1/3787 (20130101)
A61N 1/37205 (20130101)
A61N 5/1071 (20130101)
A61N 7/02 (20130101) Original (OR) Class
A61N 2005/1087 (20130101)
A61N 2007/0021 (20130101)

Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/327 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/025 (20130101)
H02J 50/15 (20160201)
H02J 50/90 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300439 Bishop
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
INVENTOR(S) Benjamin E. Bishop (South Glastonbury, Connecticut)
ABSTRACT A method for controlling the saturation level of gas in a liquid discharge includes obtaining temperature and pressure measurements of a solvent in a mixing vessel and obtaining a pressure measurement of a source feedstock in a feedstock tank, correlating the temperature and pressure measurements of the solvent to baseline data to generate a theoretical uptake rate for the source feedstock into the solvent and a theoretical flow rate of the source feedstock into the mixing vessel, and determining a required opening setting for a feedstock valve in the feedstock input line in order to achieve a desired liquid displacement in the mixing vessel. The method includes determining an uptake duration and achieving an uptake displacement equivalent to the reverse of the desired liquid displacement. The method includes generating a valve operating control law for how the feedstock valve should function in a cycle.
FILED Monday, September 28, 2015
APPL NO 14/868094
ART UNIT 1748 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 1/0005 (20130101)
B01F 1/0038 (20130101) Original (OR) Class
B01F 3/04099 (20130101)
B01F 15/0035 (20130101)
B01F 15/00155 (20130101)
B01F 15/00162 (20130101)
B01F 15/00175 (20130101)

Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers
B63G 8/08 (20130101)

Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines
F01N 3/04 (20130101)
F01N 9/00 (20130101)
F01N 13/12 (20130101)
F01N 2590/02 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 21/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300526 Propheter-Hinckley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut)
ASSIGNEE(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Tracy A. Propheter-Hinckley (Manchester, Connecticut);  James T. Auxier (Bloomfield, Connecticut);  Eric A. Hudson (Harwinton, Connecticut)
ABSTRACT A core assembly for a casting system according to an exemplary aspect of the present disclosure includes, among other things, a core that includes a body and at least one hole formed through the body and a spacer that extends through the at least one hole. The spacer includes a stud portion and a chaplet portion configured to abut a surface of the body that circumscribes the at least one hole.
FILED Monday, February 09, 2015
APPL NO 14/616940
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Foundry Moulding
B22C 9/101 (20130101)
B22C 9/108 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300570 Nelaturi et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) Sandvik Intellectual Property AB (Sandviken, Sweden)
INVENTOR(S) Saigopal Nelaturi (Palo Alto, California);  Arvind Rangarajan (Santa Clara, California);  Tolga Kurtoglu (Freemont, California);  Christian Fritz (Menlo Park, California)
ABSTRACT Automated fixture layout is approached in two distinct stages. First, the spatial locations of clamping points on the work piece are determined to ensure immobility of the fixtured part under any infinitesimal perturbation. Second, spatial locations are matched against a user-specified library of reconfigurable clamps to synthesize a valid fixture layout or configuration that includes clamps that are accessible and collision free. The spatial locations matching during the second stage can be the same spatial locations chosen in the first stage to ensure immobility, or a different set of spatial locations.
FILED Monday, February 13, 2017
APPL NO 15/431691
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Details, Components, or Accessories for Machine Tools, e.g Arrangements for Copying or Controlling; Machine Tools in General Characterised by the Construction of Particular Details or Components; Combinations or Associations of Metal-working Machines, Not Directed to a Particular Result
B23Q 3/103 (20130101) Original (OR) Class

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/40937 (20130101)
G05B 2219/31058 (20130101)
G05B 2219/37221 (20130101)
G05B 2219/49123 (20130101)

Electric Digital Data Processing
G06F 2217/06 (20130101)

Image Data Processing or Generation, in General
G06T 17/005 (20130101)
G06T 19/20 (20130101)
G06T 2210/21 (20130101)
G06T 2219/2004 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 80/40 (20151101)
Y02P 90/04 (20151101)
Y02P 90/265 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300969 Blankespoor et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
ASSIGNEE(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
INVENTOR(S) Kevin Blankespoor (Arlington, Massachusetts);  Marco da Silva (Arlington, Massachusetts);  Alex Perkins (Arlington, Massachusetts)
ABSTRACT An example method may include i) determining a first distance between a pair of feet of a robot at a first time, where the pair of feet is in contact with a ground surface; ii) determining a second distance between the pair of feet of the robot at a second time, where the pair of feet remains in contact with the ground surface from the first time to the second time; iii) comparing a difference between the determined first and second distances to a threshold difference; iv) determining that the difference between determined first and second distances exceeds the threshold difference; and v) based on the determination that the difference between the determined first and second distances exceeds the threshold difference, causing the robot to react.
FILED Monday, February 27, 2017
APPL NO 15/443899
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1694 (20130101)

Motor Vehicles; Trailers
B62D 57/02 (20130101) Original (OR) Class

Systems for Controlling or Regulating Non-electric Variables
G05D 1/027 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301012 Darrow, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) David A. Darrow, Jr. (Stratford, Connecticut);  Kevin Laitenberger (Beacon Falls, Connecticut)
ABSTRACT A rotor hub assembly for a rotary-winged aircraft includes a spool portion and a plurality of hub arms extending radially outwardly from the spool portion. A rotor blade is connectable to each hub arm. Each hub arm includes a spine portion and at least two leg portions extending from the spine portion. The spine portion and the at least two leg portions defining an I-shaped cross-section of each hub arm. A rotor assembly includes a rotor hub assembly including a spool portion and a plurality of hub arms extending radially outwardly from the spool portion. Each hub arm includes a spine portion and at least two leg portions extending from the spine portion. The spine portion and the at least two leg portions define an I-shaped cross-section of each hub arm. A rotor blade is secured to each hub arm.
FILED Wednesday, March 19, 2014
APPL NO 14/915093
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 11/04 (20130101)
B64C 27/10 (20130101)
B64C 27/32 (20130101) Original (OR) Class
B64C 27/33 (20130101)
B64C 27/35 (20130101)
B64C 27/48 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301015 Kirchen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Adrial Kirchen (Stamford, Connecticut);  Jonathon Crim (Milford, Connecticut);  Steven M. Capelle (Derby, Connecticut);  Stephen V. Poulin (Milford, Connecticut)
ABSTRACT A linkage assembly configured for use on a rotor blade having a first section and a second section, the second section being configured to rotate about a blade fold axis between an aligned position and a rotated position relative to the first section is provided. The linkage assembly includes a bracket having a first portion rotatably coupled to the first section about the blade fold axis and a second portion mounted to the second section. A spacer assembly is positioned between the bracket and an adjacent wall of the second section. The overall thickness of the spacer assembly is adjustable to control a distance between the second section and the bracket to adjust the rotated position.
FILED Friday, June 19, 2015
APPL NO 15/329431
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/46 (20130101)
B64C 27/50 (20130101) Original (OR) Class
B64C 27/54 (20130101)
B64C 27/473 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301040 Franich et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Goodrich Lighting Systems, Inc. (Oldsmar, Florida)
ASSIGNEE(S) GOODRICH LIGHTING SYSTEMS, INC. (Oldsmar, Florida)
INVENTOR(S) David Franich (Tempe, Arizona);  Philippe Lapujade (Chandler, Arizona)
ABSTRACT A dual mode light assembly for a forward position light of an aircraft includes a base, a visible light source mounted to the base that is configured to emit visible light, a covert light source mounted to the base that is configured to emit covert light, and a light shield mounted to the base. The light shield is configured to restrict transmission of the visible light to a visible light pattern and to restrict transmission of the covert light to a covert light pattern.
FILED Monday, July 09, 2018
APPL NO 16/029788
ART UNIT 2879 — Optics
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 47/02 (20130101)
B64D 47/04 (20130101)
B64D 47/06 (20130101) Original (OR) Class
B64D 2203/00 (20130101)

Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for
F21V 7/00 (20130101)
F21V 11/16 (20130101)

Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to Uses or Applications of Lighting Devices or Systems
F21W 2107/30 (20180101)

Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted
F21Y 2115/10 (20160801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301073 Cavallaro et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Paul V Cavallaro (Raynham, Massachusetts);  Andrew W Hulton (Mansfield, Massachusetts);  Gregory J Gudejko (Cranston, Rhode Island);  Dustin T Green (Fredericksburg, Virginia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Paul V Cavallaro (Raynham, Massachusetts);  Andrew W Hulton (Mansfield, Massachusetts);  Gregory J Gudejko (Cranston, Rhode Island);  Dustin T Green (Fredericksburg, Virginia)
ABSTRACT A soft transfer case for biological and chemical material is provided. The transfer case includes a film-laminated, woven textile exterior layer as a pouch resembling an open cylinder. The cylinder is capable of being clamped at each end of the cylinder. A pouch shaped and single open end elastomeric bladder capable of containing biological and chemical material can be contained by the exterior layer. The bladder requires only one seam which is used to permanently seal the open end with the material contained therein. Upon pressurization of the bladder, the exterior layer expands and a restraining force is generated between the textile layer and the clamps.
FILED Monday, August 28, 2017
APPL NO 15/688145
ART UNIT 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle
A61J 1/00 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/024 (20130101)
B32B 27/36 (20130101)

Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages
B65D 29/00 (20130101) Original (OR) Class
B65D 31/16 (20130101)
B65D 33/1641 (20130101)
B65D 53/00 (20130101)
B65D 75/525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301221 Taylor
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) SPAWAR Systems Center Pacific (San Diego, California)
ASSIGNEE(S) United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Benjamin J. Taylor (Escondido, California)
ABSTRACT A superconducting material having a strong magnetic-flux pinning by way of sites having high electronic effective mass and charge carrier density. The superconducting material involves a superconducting host material and a dopant pinning material being inert in relation to the superconducting host material and has a √{square root over (ρ)}/m* in a range less than that of the superconducting host material, the dopant pinning material doping the superconducting host material.
FILED Tuesday, September 20, 2016
APPL NO 15/270233
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/4508 (20130101) Original (OR) Class
C04B 35/6303 (20130101)
C04B 37/005 (20130101)
C04B 2235/79 (20130101)
C04B 2235/3201 (20130101)
C04B 2235/3208 (20130101)
C04B 2235/3215 (20130101)
C04B 2235/3225 (20130101)
C04B 2235/3227 (20130101)
C04B 2235/3282 (20130101)
C04B 2235/3289 (20130101)
C04B 2237/06 (20130101)
C04B 2237/34 (20130101)
C04B 2237/74 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301285 Miller et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Tennessee Research Foundation (Knoxville, Tennessee);  GTx, Inc. (Memphis, Tennessee)
ASSIGNEE(S) GTX, INC. (Memphis, Tennessee);  UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Noxville, Tennessee)
INVENTOR(S) Duane D. Miller (Collierville, Tennessee);  Jianjun Chen (Knoxville, Tennessee);  James T. Dalton (Ann Arbor, Michigan);  Chien-Ming Li (Fremont, California);  Sunjoo Ahn (Daejeon, South Korea);  Wei Li (Germantown, Tennessee)
ABSTRACT The present invention relates to a compound of formula XXII and a compound of formula 17ya, which are defined as anywhere in the specification, to a composition comprising the same, and to a method of using thereof in the treatment of various forms of cancer.
FILED Tuesday, April 21, 2015
APPL NO 14/692597
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4178 (20130101)
A61K 31/4178 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 233/02 (20130101)
C07D 233/22 (20130101)
C07D 233/54 (20130101)
C07D 263/06 (20130101)
C07D 263/14 (20130101)
C07D 263/32 (20130101)
C07D 277/04 (20130101)
C07D 277/24 (20130101)
C07D 277/28 (20130101)
C07D 277/56 (20130101)
C07D 401/04 (20130101)
C07D 401/06 (20130101)
C07D 403/04 (20130101) Original (OR) Class
C07D 413/04 (20130101)
C07D 413/06 (20130101)
C07D 417/04 (20130101)
C07D 417/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301413 Jiang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) UNIVERSITY OF WASHINGTON (Seattle, Washington)
INVENTOR(S) Shaoyi Jiang (Redmond, Washington);  Shengfu Chen (Hangzhou, China PRC)
ABSTRACT Nonfouling copolymers and hydrogels comprising positively charged repeating units or latent positively charged repeating units and negatively charged units or latent positively charged units.
FILED Tuesday, April 28, 2015
APPL NO 14/698721
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/10 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 39/20 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 220/10 (20130101) Original (OR) Class
C08F 220/26 (20130101)
C08F 220/34 (20130101)
C08F 222/1006 (20130101)

Compositions of Macromolecular Compounds
C08L 51/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301430 Tan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Loon-Seng Tan (Centerville, Ohio);  David Huabin Wang (Beavercreek, Ohio);  Jeong Jae Wie (Gyeonggi, South Korea);  Timothy J. White (Centerville, Ohio)
ABSTRACT Bis(azo-benzene) diamine monomers and a method of synthesizing the monomers are provided. The bis(azo-benzene) diamine monomers, in combination with amine reactive monomers, form polymers, such as polyimides and copolyimides, having photomechanical and thermomechanical properties.
FILED Tuesday, September 26, 2017
APPL NO 15/715414
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 245/08 (20130101)
C07C 323/48 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 69/32 (20130101)
C08G 73/10 (20130101)
C08G 73/105 (20130101)
C08G 73/1007 (20130101) Original (OR) Class
C08G 73/1039 (20130101)
C08G 73/1042 (20130101)
C08G 73/1046 (20130101)
C08G 73/1064 (20130101)
C08G 73/1067 (20130101)
C08G 73/1071 (20130101)
C08G 73/1085 (20130101)
C08G 73/1096 (20130101)

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 35/021 (20130101)
C09B 43/16 (20130101)
C09B 69/106 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301530 Guenthner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) The United States as Represented by the Secretary of the Air Force (Washington, District of Columbia);  Nano Hydrophobics, Inc. (San Francisco, California)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Andrew Guenthner (Lancaster, California);  Jeffrey Alston (Palmdale, California);  Peter H. Boyd (San Francisco, California);  Joseph M. Mabry (Lancaster, California);  Timothy W. Rost (Fremont, California)
ABSTRACT In some aspects, the present invention relates generally to self-release compositions and methods useful for the removal or prevention of mineral scaling and, more particularly, to surface coatings and surface treatments that resist, prevent, or aid in removal of mineral scaling. In some aspects, the self-release coating includes a polyhedral oligomeric silsesquioxane and a thermoplastic or an additive.
FILED Friday, August 11, 2017
APPL NO 15/675070
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/36 (20130101)
B05D 1/38 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 77/24 (20130101)
C08G 77/045 (20130101)

Compositions of Macromolecular Compounds
C08L 25/06 (20130101)
C08L 33/08 (20130101)
C08L 33/12 (20130101)
C08L 33/12 (20130101)
C08L 33/20 (20130101)
C08L 81/06 (20130101)
C08L 83/00 (20130101)
C08L 83/00 (20130101)
C08L 83/08 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/00 (20130101)
C09D 7/20 (20180101)
C09D 133/12 (20130101)
C09D 133/12 (20130101)
C09D 183/08 (20130101)
C09D 183/08 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 8/52 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301587 Krishnaswamy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Pavitra Krishnaswamy (Cambridge, Massachusetts);  Andras Kuthi (Thousand Oaks, California)
ABSTRACT Disclosed are methods and systems for subnanosecond rise time high voltage (HV) electric pulse delivery to biological loads. The system includes an imaging device and monitoring apparatus used for bio-photonic studies of pulse induced intracellular effects. The system further features a custom fabricated microscope slide having micro-machined electrodes. A printed circuit board to interface the pulse generator to the micro-machined glass slide having the cell solution is disclosed. An low-parasitic electronic setup to interface with avalanche transistor-switched pulse generation system is also disclosed. The pc-board and the slide are configured to match the output impedance of the pulse generator which minimizes reflection back into the pulse generator, and minimizes distortion of the pulse shape and pulse parameters. The pc-board further includes a high bandwidth voltage divider for real-time monitoring of pulses delivered to the cell solutions.
FILED Monday, October 31, 2016
APPL NO 15/339706
ART UNIT 1799 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/327 (20130101)
A61N 1/0408 (20130101)
A61N 1/0412 (20130101)
A61N 1/0452 (20130101)
A61N 1/0456 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 35/02 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 13/00 (20130101)

Pulse Technique
H03K 3/57 (20130101)
H03K 3/537 (20130101)
H03K 5/159 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301608 Raushel et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) The Texas A and M University System (College Station, Texas)
INVENTOR(S) Frank M. Raushel (College Station, Texas);  Andrew N. Bigley (North Zulch, Texas)
ABSTRACT Variants of phosphotriesterase have been created that exhibit enhanced hydrolysis of V-type and G-type nerve agents over wild-type phosphotriesterase. V- and G-type nerve agents have an SP and RP enantiomer. The SP enantiomers are more toxic. V-type nerve agents are among the most toxic substances known. Variants of phosphotriesterase can prefer to hydrolyze one enantiomer of VX over the other enantiomer.
FILED Friday, June 19, 2015
APPL NO 15/320490
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus
A62D 3/02 (20130101)
A62D 2101/02 (20130101)
A62D 2101/26 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101) Original (OR) Class

Enzymes
C12Y 301/03008 (20130101)
C12Y 301/08001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301624 Ting et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts);  Aalborg University (Aalborg, Denmark)
INVENTOR(S) David T. Ting (Dover, Massachusetts);  Daniel A. Haber (Chestnut Hill, Massachusetts);  Shyamala Maheswaran (Lexington, Massachusetts);  Francesca Bersani (Turin, Italy);  Anders M. Naar (Arlington, Massachusetts);  Mihir Shivadatta Rajurkar (Worcester, Massachusetts);  Sakari Kauppinen (Holte, Denmark);  Andreas Petri (Frederiksberg, Denmark)
ABSTRACT Methods for treating cancer, e.g., cancer of epithelial origin, by specifically targeting human satellite II (HSATII) using sequence specific agents such as oligonucleotides. As shown herein, the hetero chromatic HSATII satellite repeat is silenced in normal cells, but massively over expressed in epithelial cancers and in cancer cell lines when grown as xenografts or in 3D culture. Induction of HSATII RNA, either in xenografts or using in vitro reconstitution models, suggests the appearance of complementary DNA intermediates.
FILED Thursday, June 25, 2015
APPL NO 15/321391
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/315 (20130101)
C12N 2310/321 (20130101)
C12N 2310/341 (20130101)
C12N 2310/3231 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301630 Philpot et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Benjamin David Philpot (Durham, North Carolina);  Mark John Zylka (Chapel Hill, North Carolina);  Bryan Leo Roth (Durham, North Carolina);  John Arthur Allen (North Billerica, Massachusetts);  Hsien-Sung Huang (Kaohsiung, Taiwan)
ABSTRACT The present invention provides methods and compositions for inducing expression of Ube3a in a cell by contacting the cell with a topoisomerase inhibitor. Particular embodiments include a method of treating a genomic imprinting disorder, such as Angelman syndrome, in a subject by administering to the subject an effective amount of a topoisomerase inhibitor.
FILED Thursday, June 22, 2017
APPL NO 15/630664
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/473 (20130101)
A61K 31/496 (20130101)
A61K 31/713 (20130101)
A61K 31/4741 (20130101)
A61K 31/4745 (20130101)
A61K 31/5377 (20130101)
A61K 31/7048 (20130101)
A61K 31/7105 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/635 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301667 Cao
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Research, Development and Engineering Command (RDECOM)
Edgewood Chemical Biological Center (ECBC)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Yunwei Charles Cao (Gainesville, Florida)
ABSTRACT Described herein are fluid-manipulation-based devices. Fluid manipulations as described herein can be configured to perform assays on biological samples. In an embodiment, the device includes a reaction chamber, which can includes an integrated sample isolation module, a cell lysis module, a biological target purification module, and an assay mixing module, which can include a microbead with a capture molecule coupled thereto and a nanoparticle having a probe molecule coupled thereto via a label, which can be a spectroscopic label. In an embodiment, the capture and probe molecules can be configured to be coupled together via a biological target to form a biological molecule bead complex. Devices and methods as described herein can manipulate and analyze nanoliter volumes of fluid, microliter volumes of fluid, milliliter volumes of fluid, or greater. Embodiments of the present disclosure can enable random biological assays and rapid, simultaneous analysis of multiple biological samples.
FILED Friday, November 18, 2016
APPL NO 15/355306
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502761 (20130101)
B01L 7/00 (20130101)
B01L 2200/10 (20130101)
B01L 2200/0631 (20130101)
B01L 2200/0636 (20130101)
B01L 2200/0647 (20130101)
B01L 2300/087 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/0424 (20130101)
B01L 2400/0487 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101) Original (OR) Class
C12Q 1/6816 (20130101)
C12Q 1/6816 (20130101)
C12Q 2563/137 (20130101)
C12Q 2563/155 (20130101)
C12Q 2563/155 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/587 (20130101)
G01N 33/54313 (20130101)
G01N 35/1097 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301684 Tavazoie et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) The Rockefeller Universtiy (New York, New York)
ASSIGNEE(S) The Rockefeller University (New York, New York)
INVENTOR(S) Sohail Tavazoie (New York, New York);  Nils Halberg (Brooklyn, New York);  Kim Png (Singapore, Singapore)
ABSTRACT This invention concerns pathological angiogenesis and cancer, related treatment methods, and related compositions. Also disclosed are related diagnosis kits and methods.
FILED Thursday, June 22, 2017
APPL NO 15/629971
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1709 (20130101)
A61K 38/1709 (20130101)
A61K 39/3955 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 16/18 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 15/1135 (20130101)
C12N 2310/113 (20130101)
C12N 2310/141 (20130101)
C12N 2320/11 (20130101)
C12N 2320/12 (20130101)
C12N 2330/31 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/136 (20130101)
C12Q 2600/158 (20130101)
C12Q 2600/178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301719 Paquette et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri);  Intel Corporation (Santa Clara, California)
INVENTOR(S) Michelle Paquette (Overland Park, Kansas);  Bradley Nordell (Kansas City, Missouri);  Anthony N. Caruso (Overland Park, Kansas);  Sean King (Hillsboro, Oregon)
ABSTRACT A method of forming a low-dielectric-constant amorphous hydrogenated boron carbide film on a substrate includes positioning the substrate within a plasma enhanced chemical vapor deposition (PECVD) chamber, providing a boron carbide precursor and introducing the boron carbide precursor into a carrier gas to form a carrier gas-precursor mixture. The method also includes introducing the carrier gas-precursor mixture into the PECVD chamber. The method also includes applying radio frequency power within the PECVD chamber to the carrier gas-precursor mixture to form one or more plasmas containing one or more species containing at least one of boron, carbon or hydrogen. The method also includes forming the low-dielectric-constant amorphous hydrogenated boron carbide film on the substrate within the PECVD chamber.
FILED Wednesday, April 06, 2016
APPL NO 15/092604
ART UNIT 1718 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/32 (20130101)
C23C 16/455 (20130101)
C23C 16/505 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0262 (20130101)
H01L 21/02365 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301947 Propheter-Hinckley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Tracy A. Propheter-Hinckley (Rocky Hill, Connecticut);  Steven Bruce Gautschi (Milton, Massachusetts);  San Quach (Southington, Connecticut)
ABSTRACT A method of manufacturing a component for a gas turbine engine according to an exemplary aspect of the present disclosure includes forming the component with a first manufacturing technique to include a first cavity and a second cavity, and a microcircuit in fluid communication with the first cavity, the component including an outer wall and a ribbed portion or a bulged portion extending from the outer wall. The exemplary method includes forming a plunged hole with a second manufacturing technique different from the first manufacturing technique to intersect at least a portion of the microcircuit and extend into the ribbed portion or the bulged portion.
FILED Tuesday, June 05, 2018
APPL NO 15/997943
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Foundry Moulding
B22C 9/04 (20130101)
B22C 9/10 (20130101)

Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 15/02 (20130101)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/186 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2230/14 (20130101)
F05D 2230/211 (20130101)
F05D 2260/204 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 7/00 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49234 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301958 Hough et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Matthew Andrew Hough (West Hartford, Connecticut);  Christopher Corcoran (Manchester, Connecticut);  Jeffrey S. Beattie (South Glastonbury, Connecticut)
ABSTRACT A gas turbine engine includes a turbine section. The turbine section includes a disk that is rotatable about an axis. A plurality of turbine blades are mounted around a periphery of the disk, and a plurality of seals are arranged between the turbine blades and the periphery of the disk. Each of the seals includes, with respect to the axis, a radially outer surface and a radially inner surface. The radially inner surface includes a plurality of protrusions.
FILED Thursday, August 21, 2014
APPL NO 15/021945
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/22 (20130101)
F01D 11/006 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2250/75 (20130101)
F05D 2250/181 (20130101)
F05D 2250/182 (20130101)
F05D 2250/183 (20130101)
F05D 2260/22141 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301961 Davis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Timothy M. Davis (Kennebunk, Maine);  Brian Duguay (Berwick, Maine)
ABSTRACT An active clearance control system of a gas turbine engine includes a multiple of blade outer air seal assemblies and a sync ring with a multiple of graduation sets. Each of the graduation sets is associated with one of the multiple of blade outer air seal assemblies. An active clearance control system of a gas turbine engine includes a sync ring with a multiple of graduation sets. Each of the graduation sets includes a multiple of graduations to define an associated radial position for each of a respective multiple of blade outer air seal assemblies.
FILED Wednesday, July 23, 2014
APPL NO 14/913785
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 11/08 (20130101)
F01D 11/14 (20130101)
F01D 11/22 (20130101) Original (OR) Class

Non-positive-displacement Pumps
F04D 29/164 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2260/50 (20130101)
F05D 2270/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301967 Slavens et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Thomas N. Slavens (Vernon, Connecticut);  Steven Bruce Gautschi (Naugatuck, Connecticut)
ABSTRACT A turbine vane assembly for a gas turbine engine is disclosed and includes an airfoil rotatable about a first axis transverse to an engine longitudinal axis. The airfoil includes an endwall and at least one protrusion disposed on the endwall configured for obstructing flow through a gap between the endwall and a static structure of the gas turbine engine.
FILED Friday, October 17, 2014
APPL NO 15/028468
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/02 (20130101)
F01D 5/12 (20130101)
F01D 9/041 (20130101)
F01D 11/001 (20130101)
F01D 11/04 (20130101)
F01D 17/14 (20130101)
F01D 17/162 (20130101)
F01D 25/12 (20130101) Original (OR) Class

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/04 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/35 (20130101)
F05D 2250/182 (20130101)
F05D 2250/183 (20130101)
F05D 2250/184 (20130101)
F05D 2260/20 (20130101)

Pistons; Cylinders; Sealings
F16J 15/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302041 Czapski, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Joseph J. Czapski, Jr. (New Britain, Connecticut);  David C. Pimenta (Rocky Hill, Connecticut);  Chung-Han Liou (Stoneham, Massachusetts);  Paul R. Senofonte (Jupiter, Florida);  Steven D. Roberts (Moodus, Connecticut)
ABSTRACT Tracks (35), fastened to static structure of an aircraft engine nozzle, guide sliders (32) journaled in struts (27, 28) fastened to a flap (23) of the nozzle. Each slider and attached journal axle or bolt (33) is formed of cobalt, and each track slider surface (61) and journal bushings (43, 44) are formed of a nickel alloy to reduce wear from rubbing. Track slides (40, 41) are mounted to the static structure of the nozzle by blind bolts (68) having a tool recess (70) at its threaded tip to prevent the bolt (68) from turning as a nut is secured. Each slider has limited rotation due to a pin (102), thereon engaging a slot in a tab (100) of the bushing (43) to assist in inserting the slider (32) into the beveled ends of the tracks (35, 36), when mounting or replacing a flap.
FILED Friday, December 09, 2016
APPL NO 15/373948
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Jet-propulsion Plants
F02K 1/06 (20130101) Original (OR) Class
F02K 1/09 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/36 (20130101)
F05D 2260/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302117 Latcha et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Tank Automotive Research, Development and Engineering Center (TARDEC)
APPLICANT(S) Oakland University (Rochester, Michigan)
ASSIGNEE(S) OAKLAND UNIVERSITY (Rochester, Michigan)
INVENTOR(S) Michael A. Latcha (Redford, Michigan);  Sayed A. Nassar (Northville, Michigan);  Mehmet H. Uras (Ann Arbor, Michigan)
ABSTRACT A de-coupling mechanism includes a link slidably received in a link aperture of a bracket. A pin is slidably received in a pin bore of the link and a receiving bore of the bracket. A first block is connected to the bracket and includes an initiator receiving passage in communication with the pin bore. An initiator is positioned in the initiator receiving passage and retained against a connecting passage edge and oppositely contacts an end face of a cap connected to the first block. A second block connected to the bracket includes a longitudinal channel having a channel diameter larger than a pin diameter so the pin is freely displaceable into the longitudinal channel. An end face of a retaining cap is connected to a second block end wall. The retaining cap includes a stepped portion having a step diameter smaller than the channel diameter and the pin diameter.
FILED Wednesday, October 05, 2016
APPL NO 15/285524
ART UNIT 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing
F16B 19/00 (20130101) Original (OR) Class

Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 7/042 (20130101)
F41H 7/046 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 3/006 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 403/1633 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302427 Broe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) NSWC CRANE (Crane, Indiana)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Kevin Michael Broe (Bloomington, Indiana);  Tyler Mullis (Bloomfield, Indiana);  Mark Halter (Washinqton, Indiana);  Steven Mowery (Mitchell, Indiana)
ABSTRACT Various embodiments of this disclosure relates to a methods and related apparatuses for rapidly and visually determining and verifying multiple interface alignments of parts within a system. In particular, embodiments of the invention are directed to methods and related apparatuses enabling rapid visual determining and verifying multiple interface alignments of parts within at least one first system interface part that cooperatively engage with at least one second system's interface part each having at least one system-sub-system assembly alignment datum that requires the at least one first and second system's interface parts cooperatively and engagingly align within multiple respective tolerances of alignment.
FILED Tuesday, August 08, 2017
APPL NO 15/671319
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Apparatus for Launching Projectiles or Missiles From Barrels, e.g Cannons; Launchers for Rockets or Torpedoes; Harpoon Guns
F41F 3/04 (20130101)

Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/27 (20130101) Original (OR) Class
G01B 11/0608 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302541 Hagen
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Gregory S. Hagen (Glastonbury, Connecticut)
ABSTRACT A gas turbine engine, a method, and a system for detecting oil debris are provided. The gas turbine engine includes an oil debris monitor sensor configured to detects oil debris in an oil flow, and generate a sensor signal based on the detected oil debris, a controller configured to control the oil flow through the oil debris monitor sensor using a plurality of valves, and a signal processor configured to receive the sensor signal from the oil debris monitor and to receive a valve system configuration from the controller, the signal processor further configured to generates a health indicator based on the sensor signal and valve configuration.
FILED Wednesday, September 14, 2016
APPL NO 15/264637
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 21/003 (20130101)
F01D 21/10 (20130101)
F01D 25/18 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/06 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2260/80 (20130101)
F05D 2260/98 (20130101)
F05D 2260/607 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/02 (20130101)
G01N 15/0606 (20130101) Original (OR) Class
G01N 27/74 (20130101)
G01N 33/2888 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302586 Sun et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jeong Yun Sun (Cambridge, Massachusetts);  Christoph Matthias Keplinger (Cambridge, Massachusetts);  Zhigang Suo (Lexington, Massachusetts);  George M. Whitesides (Newton, Massachusetts)
ABSTRACT A class of devices enabled by ionic conductors is highly stretchable, fully transparent to light of all colors, biocompatible or biodegradable, and capable of operation at frequencies beyond 10 kilohertz and voltages above 10 kilovolts. These devices enabled by ionic conductors can be used as large strain actuators, full-range loudspeakers, as strain or pressure sensors and as stretchable interconnects. The electromechanical transduction is achieved without electrochemical reaction. When large stretchability and high optical transmittance are required, the ionic conductors have lower sheet resistance than all existing electronic conductors.
FILED Thursday, April 10, 2014
APPL NO 14/768850
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/02 (20130101)
G01N 27/305 (20130101) Original (OR) Class
G01N 27/3335 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302601 McGill et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) R. Andrew McGill (Lorton, Virginia);  Robert Furstenberg (Largo, Maryland);  Viet K. Nguyen (Gaithersburg, Maryland);  Chris Kendziora (Burke, Virginia);  Michael Papantonakis (Washington, District of Columbia);  Todd H. Stievater (Arlington, Virginia)
ABSTRACT A chemical detector for rapid, simultaneous detection of multiple chemicals including chemical warfare agents, toxic industrial chemicals, and explosives having one or more gas chromatography columns each with a chemosorbent or a chemo-reactive stationary phase and an infrared-transparent base, a bright infrared light source, a mechanism to direct the light source to any point along any of the columns, and an infrared sensor. Another disclosed detector has one or more gas chromatography columns each on the surface of a substrate having at least one infrared-transparent waveguide pattern, a bright infrared light source, and at least one ring resonator for each column, where each ring resonator is coated with a chemosorbent or a chemo-reactive stationary phase, and where each ring resonator spectroscopically probes the stationary phase. Also disclosed are the related methods for chemical detection.
FILED Tuesday, March 21, 2017
APPL NO 15/464378
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/39 (20130101)
G01N 21/0332 (20130101)
G01N 21/552 (20130101)
G01N 21/658 (20130101)
G01N 21/3504 (20130101)
G01N 21/7746 (20130101)
G01N 30/02 (20130101) Original (OR) Class
G01N 30/48 (20130101)
G01N 30/74 (20130101)
G01N 30/6034 (20130101)
G01N 30/6082 (20130101)
G01N 2021/4761 (20130101)
G01N 2030/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302649 Clinton et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Charles M. Clinton (Clarksburg, Maryland);  Eli N. Glezer (Chevy Chase, Maryland);  Bandele Jeffrey-Coker (Darnestown, Maryland);  Sandor L. Kovacs (Middletown, Maryland);  Sudeep M. Kumar (Gaithersburg, Maryland);  George Sigal (Rockville, Maryland);  Carl Stevens (Silver Spring, Maryland);  Michael Vock (Loveland, Ohio)
ASSIGNEE(S) Meso Scale Technologies, LLC (Gaithersburg, Maryland)
INVENTOR(S) Charles M. Clinton (Clarksburg, Maryland);  Eli N. Glezer (Chevy Chase, Maryland);  Bandele Jeffrey-Coker (Darnestown, Maryland);  Sandor L. Kovacs (Middletown, Maryland);  Sudeep M. Kumar (Gaithersburg, Maryland);  George Sigal (Rockville, Maryland);  Carl Stevens (Silver Spring, Maryland);  Michael Vock (Loveland, Ohio)
ABSTRACT We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
FILED Thursday, December 21, 2006
APPL NO 11/642968
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Applying Closure Members to Bottles Jars, or Similar Containers; Opening Closed Containers
B67B 7/24 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/66 (20130101)
G01N 21/6452 (20130101)
G01N 33/582 (20130101) Original (OR) Class
G01N 33/5302 (20130101)
G01N 35/028 (20130101)
G01N 35/109 (20130101)
G01N 35/1002 (20130101)
G01N 35/1011 (20130101)
G01N 35/1079 (20130101)
G01N 35/1081 (20130101)
G01N 2035/0405 (20130101)
G01N 2035/0425 (20130101)
G01N 2035/1025 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 83/9314 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302711 Wang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Jian-Ping Wang (Shoreview, Minnesota);  Angeline Klemm Smith (Hillsboro, Oregon);  Mahdi Jamali (Folsom, California);  Zhengyang Zhao (Minneapolis, Minnesota)
ABSTRACT An article may include a substantially perpendicularly magnetized free layer having a first magnetic orientation in the absence of an applied magnetic field. The article may also include a spin Hall channel layer configured to conduct a spin current configured to subject the perpendicularly magnetized free layer to a magnetic switching torque and a substantially in-plane magnetized bias layer configured to bias the substantially perpendicularly magnetized free layer to a second magnetic orientation. The second magnetic orientation is different than the first magnetic orientation and is out of a plane of the substantially perpendicularly magnetized free layer.
FILED Monday, March 12, 2018
APPL NO 15/918942
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/075 (20130101) Original (OR) Class
G01R 33/077 (20130101)
G01R 33/1284 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 43/04 (20130101)
H01L 43/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302722 Alsop et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) David Alsop (Newton, Massachusetts);  Gopal Varma (Boston, Massachusetts)
ASSIGNEE(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) David Alsop (Newton, Massachusetts);  Gopal Varma (Boston, Massachusetts)
ABSTRACT A system and method for producing a report about a subject from data collected from the subject using a magnetic resonance imaging (MRI] system. The method includes directing the MRI system to perform a pulse sequence to manipulate exchangeable magnetization in the subject and acquiring, with the MRI system, imaging data from the subject in response to the pulse sequence. The method also includes analyzing the effects of the frequencies of applied RF energy on the imaging data to identify inhomogeneous lines formed by a summation of multiple sublines centered at multiple different frequencies. The method further includes generating a report pertaining to inhomogeneous magnetization transfer occurring in the subject in response to the pulse sequence.
FILED Thursday, March 13, 2014
APPL NO 14/776872
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/4041 (20130101)
A61B 5/7278 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/50 (20130101)
G01R 33/4828 (20130101)
G01R 33/5605 (20130101) Original (OR) Class
G01R 33/5659 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302808 Chiao
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Raymond Chiao (Oakland, California)
ABSTRACT A gravitational radiation communication system. The system includes a gravitational radiation transmitter and a gravitational radiation receiver. Each of the transmitter and the receiver includes a first cylindrical superconducting cavity, having a first length, a first diameter, and an entrance aperture for electromagnetic radiation; a second cylindrical superconducting cavity, having a second length, a second diameter, and a first aperture for gravitational radiation, the second cavity being coaxial with and adjacent the first cavity; and a superconducting movable membrane positioned between the first cavity and the second cavity and configured to provide parametric amplification of electromagnetic fields in the second cavity. The first aperture is configured to pass gravitational radiation.
FILED Thursday, February 25, 2016
APPL NO 15/548375
ART UNIT 2878 — Optics
CURRENT CPC
Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 7/00 (20130101) Original (OR) Class

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 12/06 (20130101)
H01B 12/12 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 39/08 (20130101)
H01L 39/14 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 7/04 (20130101)
H01P 7/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302864 Reano et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Ronald M. Reano (Columbus, Ohio);  Li Chen (Edison, New Jersey)
ABSTRACT An example method of forming a deterministic thin film from a crystal substrate is described herein. The method can include implanting ions into a surface of the crystal substrate to form a thin film crystal layer, and bonding the crystal substrate and a handle substrate to form a bilayer bonding interface between the crystal substrate and the handle substrate. The method can also include exfoliating the thin film crystal layer from the crystal substrate, patterning the thin film crystal layer to define a deterministic thin film, etching one or more trenches in the thin film crystal layer, etching the bilayer bonding interface via the one or more trenches, and releasing the deterministic thin film from the handle substrate.
FILED Friday, June 02, 2017
APPL NO 15/612087
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/12 (20130101)
G02B 6/126 (20130101)
G02B 6/132 (20130101)
G02B 6/136 (20130101)
G02B 6/1347 (20130101) Original (OR) Class
G02B 2006/1204 (20130101)
G02B 2006/12042 (20130101)
G02B 2006/12045 (20130101)
G02B 2006/12078 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/035 (20130101)
G02F 2202/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302889 Chin et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Patricia D. Chin (Redondo Beach, California);  John D. Isker (Sun City, California)
ABSTRACT A gimbal transmission cable management system is disclosed. The system can include a first gimbal portion and a second gimbal portion rotatable relative to one another to provide rotation about a gimbal axis. The system can also include a cable retainer fixed relative to one of the first and second gimbal portions and defining a cable volume between the cable retainer and at least one of the first and second gimbal portions. In addition, the system can include a transmission cable coiled about the gimbal axis within the cable volume. Bi-directional relative rotation of the first and second gimbal portions can alternately coil and uncoil a portion of the transmission cable about the gimbal axis within the cable volume.
FILED Tuesday, October 09, 2018
APPL NO 16/155788
ART UNIT 3632 — Static Structures, Supports and Furniture
CURRENT CPC
Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 3/16 (20130101)

Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports
F16M 13/022 (20130101)

Weapon Sights; Aiming
F41G 7/2213 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/003 (20130101)
G01S 7/4818 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/4457 (20130101)
G02B 6/4478 (20130101) Original (OR) Class

Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines
H02G 3/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302974 Goeders et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S) James Goeders (Plymouth, Minnesota);  Matthew Edward Lewis Jungwirth (Golden Valley, Minnesota)
ABSTRACT Preparation cell systems and methods are described herein. One example of a system for a preparation cell includes a laser coupled to a fiber bundle comprising a plurality of fibers, a preparation cell to prepare a state of laser light received by the fiber bundle, and an exiting fiber bundle coupled to the preparation cell.
FILED Tuesday, May 02, 2017
APPL NO 15/584456
ART UNIT 2874 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/645 (20130101)
G01N 2021/6484 (20130101)
G01N 2201/067 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/11 (20130101)
G02F 1/035 (20130101)
G02F 1/113 (20130101)
G02F 1/0115 (20130101) Original (OR) Class
G02F 1/125 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)
G06N 99/002 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/0018 (20130101)
H01J 49/424 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/0085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303541 Milor et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Linda Milor (Atlanta, Georgia);  Woongrae Kim (Atlanta, Georgia);  Taizhi Liu (Atlanta, Georgia)
ABSTRACT Methods and systems have been proposed to estimate the remaining lifetime of an electronic integrated circuit that incorporates error-correcting code memory by using the failed memory bits as an indicator for the remaining lifetime of the circuit. The number of failed memory bits correlates with the remaining lifetime of the circuit, but varies as a function of wearout mechanism and use conditions. The methodology incorporates algorithms and test patterns to diagnose the cause of memory cell failure. By linking the failed bits to the wearout mechanism and by using lifetime simulation, the remaining lifetime of the circuit is estimated.
FILED Wednesday, March 01, 2017
APPL NO 15/446776
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/073 (20130101)
G06F 11/079 (20130101) Original (OR) Class
G06F 17/5022 (20130101)
G06F 17/5036 (20130101)

Static Stores
G11C 29/02 (20130101)
G11C 29/24 (20130101)
G11C 29/70 (20130101)
G11C 29/12005 (20130101)
G11C 29/50004 (20130101)
G11C 29/50016 (20130101)
G11C 2029/1208 (20130101)
G11C 2029/3602 (20130101)
G11C 2029/5002 (20130101)
G11C 2029/5004 (20130101)
G11C 2029/5006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303735 Kaul et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Himanshu Kaul (Portland, Oregon);  Mark A. Anders (Hillsboro, Oregon);  Sanu K. Mathew (Hillsboro, Oregon)
ABSTRACT Systems, apparatuses, and methods for k-nearest neighbor (KNN) searches are described. In particular, embodiments of a KNN accelerator and its uses are described. In some embodiments, the KNN accelerator includes a plurality of vector partial distance computation circuits each to calculate a partial sum, a minimum sort network to sort partial sums from the plurality of vector partial distance computation circuits to find k nearest neighbor matches and a global control circuit to control aspects of operations of the plurality of vector partial distance computation circuits.
FILED Wednesday, November 18, 2015
APPL NO 14/944828
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 16/90335 (20190101)
G06F 17/10 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00986 (20130101)
G06K 9/6276 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303763 Beller et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charles E. Beller (Baltimore, Maryland);  Paul J. Chase (Fairfax, Virginia);  Richard Darden (Leesburg, Virginia);  Michael Drzewucki (Woodbridge, Virginia);  Edward G. Katz (Washington, District of Columbia);  Christopher Phipps (Arlington, Virginia)
ABSTRACT An apparatus comprising a memory and a processor configured for semi-autonomous natural language processing domain adaptation related activities. The processor coupled to the memory and configured to identify a corpus of documents of an evaluation domain and generate a first lexicon based on the corpus of documents of the evaluation domain, and determine a threshold that indicates a sufficiency of domain adaptation of the evaluation domain based at least in part on the first lexicon. The processor is further configured to identify a corpus of documents of a client domain, generate a second lexicon based on the corpus of documents of the client domain, determine a metric associated with the corpus of documents of the client domain and the second lexicon, and determine that domain adaptation of the client domain is complete when the metric exceeds the threshold.
FILED Friday, January 06, 2017
APPL NO 15/400300
ART UNIT 2659 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC
Electric Digital Data Processing
G06F 16/93 (20190101)
G06F 16/3329 (20190101)
G06F 16/3344 (20190101)
G06F 17/277 (20130101) Original (OR) Class
G06F 17/2735 (20130101)
G06F 17/2785 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303766 Ackermann et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Christopher F. Ackermann (Chantilly, Virginia);  Charles E. Beller (Baltimore, Maryland);  Stephen A. Boxwell (Columbus, Ohio);  Stanley J. Vernier (Grove City, Ohio)
ABSTRACT Embodiments can provide a computer implemented method, in a data processing system comprising a processor and a memory comprising instructions which are executed by the processor to cause the processor to implement a mixed-language question answering supplement system, the method comprising receiving a question in a target language; applying natural language processing to parse the question into at least one focus; for each focus, determining if one or more target language verbs share direct syntactic dependency with the focus; for each of the one or more verbs sharing direct syntactic dependency, determining if one or more target language entities share direct syntactic dependency with the verb; determining one or more Abstract Universal Verbal Types associated with each verb; for each of the one or more Abstract Universal Verbal Types, determining whether a dependency between a source language entity and a source language verb is of the same type as the dependency between the target language verb and the target language entity; if the dependency is similar, returning the source language entity as a member of a set; and if the set is full, returning an answer in the target language to the question in the target language.
FILED Friday, June 08, 2018
APPL NO 16/003772
ART UNIT 2657 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC
Electric Digital Data Processing
G06F 17/275 (20130101)
G06F 17/278 (20130101) Original (OR) Class
G06F 17/2755 (20130101)
G06F 17/2775 (20130101)
G06F 17/2785 (20130101)
G06F 17/2827 (20130101)
G06F 17/30976 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303767 Ackermann et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Christopher F. Ackermann (Chantilly, Virginia);  Charles E. Beller (Baltimore, Maryland);  Stephen A. Boxwell (Columbus, Ohio);  Stanley J. Vernier (Grove City, Ohio)
ABSTRACT Embodiments can provide a computer implemented method, in a data processing system comprising a processor and a memory comprising instructions which are executed by the processor to cause the processor to implement a mixed-language question answering supplement system, the method comprising receiving a question in a target language; determining the question cannot be answered using a target-language only corpus; applying natural language processing to parse the question into at least one focus; for each focus, determining if one or more target language verbs share direct syntactic dependency with the focus; for each of the one or more verbs sharing direct syntactic dependency, determining if one or more target language entities share direct syntactic dependency with the verb; determining one or more Abstract Universal Verbal Types associated with each verb; for each of the one or more Abstract Universal Verbal Types, determining whether a dependency between a source language entity and a source language verb is of the same type as the dependency between the target language verb and the target language entity; if the dependency is similar, returning the source language entity as a member of a set; populating the set of returned source language entities for each focus in the target language question; identifying one or more parallel passages wherein all core arguments are matched; for each parallel passage: identifying the presence or absence of oblique nominal arguments; and measuring the precision of the oblique nominal arguments in the parallel passages against those present in the target language question; and returning an answer to the target question in the target language based on a scoring of the parallel passages based on the accuracy of their respective oblique nominal arguments.
FILED Friday, June 08, 2018
APPL NO 16/003794
ART UNIT 2657 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC
Electric Digital Data Processing
G06F 17/275 (20130101)
G06F 17/278 (20130101) Original (OR) Class
G06F 17/2755 (20130101)
G06F 17/2785 (20130101)
G06F 17/3043 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/006 (20130101)
G06N 99/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303768 Divakaran et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) SRI International (Menlo Park, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Ajay Divakaran (Monmouth Junction, New Jersey);  Behjat Siddiquie (Plainsboro, New Jersey);  David Chisholm (Menlo Park, California);  Elizabeth Shriberg (Berkeley, California)
ABSTRACT Technologies to detect persuasive multimedia content by using affective and semantic concepts extracted from the audio-visual content as well as the sentiment of associated comments are disclosed. The multimedia content is analyzed and compared with a persuasiveness model.
FILED Friday, October 02, 2015
APPL NO 14/874348
ART UNIT 2659 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC
Electric Digital Data Processing
G06F 17/241 (20130101)
G06F 17/271 (20130101)
G06F 17/2765 (20130101)
G06F 17/2785 (20130101) Original (OR) Class
G06F 17/30867 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00718 (20130101)
G06K 9/00744 (20130101)

Pictorial Communication, e.g Television
H04N 21/4532 (20130101)
H04N 21/4668 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303827 Shen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) Rolls-Royce Corporation (Indianapolis, Indiana)
ASSIGNEE(S) Rolls-Royce Corporation (Indianapolis, Indiana)
INVENTOR(S) Gangshu Shen (Carmel, Indiana);  Eugene Sun (Carmel, Indiana);  Stephanie M. Janicek (Mooresville, Indiana);  Robert A. Ress, III (Carmel, Indiana);  Brian Drier (Indianapolis, Indiana);  Mark E. Bartolomeo (Brownsburg, Indiana)
ABSTRACT An example system may include a computing device including a finite element analysis module solving for a finite element model representing a component including a metal or an alloy and including a plurality of respective elements. The finite element analysis module may solve a respective stress St and a respective temperature Tt at each respective element during the predetermined cooling operating. The finite element analysis module may determine a respective impact energy ET based on the temperature Tt and cooling rate, using a predetermined cooling rate-dependent energy relationship that relates a temperature of the metal or the alloy to an impact energy, determine a respective weakness index Wt=[A×ET/St]n (A being a predetermined constant, n being a predetermined real number greater than or equal to 1), and identify a respective element having a minimum weakness index less than a predetermined weakness index threshold as a cracking-prone element.
FILED Tuesday, April 05, 2016
APPL NO 15/091086
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 1/18 (20130101)
C21D 11/005 (20130101)
C21D 2211/001 (20130101)
C21D 2211/008 (20130101)

Electric Digital Data Processing
G06F 17/5018 (20130101) Original (OR) Class
G06F 2217/16 (20130101)
G06F 2217/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303861 Homescu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) IMMUNANT, INC. (Irvine, California)
ASSIGNEE(S) IMMUNANT, INC. (Irvine, California)
INVENTOR(S) Andrei Homescu (Irvine, California);  Stephen J. Crane (Irvine, California);  Per Larsen (Irvine, California)
ABSTRACT The present invention features a system in which dynamic code randomization may be used in concert with enforcement-based mitigation policies to optimally secure a software code. A privileged, external execution context is employed when rewriting (randomizing) the software code. The rewritten code is then reloaded and executed in a less privileged execution context. Finally, the system ensures that the less privileged execution context is authorized to load and execute the code before rewriting.
FILED Monday, January 15, 2018
APPL NO 15/871663
ART UNIT 2191 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 8/41 (20130101)
G06F 8/70 (20130101)
G06F 9/45558 (20130101)
G06F 21/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304006 Keshava et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts)
INVENTOR(S) Nirmal Keshava (Needham, Massachusetts);  Laura Jane Mariano (Watertown, Massachusetts)
ABSTRACT A method and system for predicting the onset of a disease is provided. According to one example, the method includes receiving patient data including a first input sample of a first data type and a second input sample of a second data type, the first data type including discrete data and the second data type including continuous data, receiving a training data set including a first plurality of training samples of the first data type and a corresponding second plurality of training samples of the second data type, providing the first input sample and the first plurality of training samples to a first kernel function of a multiple kernel decision function, providing the second input sample and the second plurality of training samples to a second kernel function of the multiple kernel decision function, performing at least one calculation using the multiple kernel decision function to produce at least one result, and determining a probability of whether the patient data indicates that the patient will develop the disease based on the at least one result of the multiple kernel decision function.
FILED Tuesday, February 18, 2014
APPL NO 14/183018
ART UNIT 2122 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 19/00 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101) Original (OR) Class

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304199 Menozzi
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Applied Research Associates, Inc. (Albuquerque, New Mexico)
ASSIGNEE(S) Applied Research Associates, Inc. (Albuquerque, New Mexico)
INVENTOR(S) Alberico Menozzi (Raleigh, North Carolina)
ABSTRACT The described technology regards an augmented reality system and method for estimating a position of a location of interest relative to the position and orientation of a display, including a retroactive update to a previously rendered estimate of the position of the orientation of the display stored in a rewind buffer. Systems of the described technology include including a plurality of sensors, a processing module or other computation means, and a database. Methods of the described technology use data from the sensor package useful to accurately render graphical user interface information on a display.
FILED Thursday, September 14, 2017
APPL NO 15/704934
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/165 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/017 (20130101)
G02B 27/0093 (20130101)
G02B 2027/0138 (20130101)
G02B 2027/0141 (20130101)
G02B 2027/0181 (20130101)

Electric Digital Data Processing
G06F 1/163 (20130101)
G06F 3/01 (20130101)
G06F 3/011 (20130101)
G06F 3/04817 (20130101)
G06F 11/00 (20130101)

Image Data Processing or Generation, in General
G06T 5/20 (20130101)
G06T 7/33 (20170101) Original (OR) Class
G06T 11/00 (20130101)
G06T 19/006 (20130101)
G06T 2200/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304200 Menozzi
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Applied Research Associates, Inc. (Albuquerque, New Mexico)
ASSIGNEE(S) Applied Research Associates, Inc. (Albuquerque, New Mexico)
INVENTOR(S) Alberico Menozzi (Raleigh, North Carolina)
ABSTRACT The described technology regards an augmented reality system and method for estimating a position of a location of interest relative to the position and orientation of a display, using a forward buffer to store current and predicted position estimates calculated by the methods of the present invention. Systems of the described technology include including a plurality of sensors, a processing module or other computation means, and a database. Methods of the described technology use data from the sensor package useful to accurately render graphical user interface information on a display.
FILED Thursday, September 14, 2017
APPL NO 15/704954
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/165 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/017 (20130101)
G02B 27/0093 (20130101)
G02B 2027/0138 (20130101)
G02B 2027/0141 (20130101)
G02B 2027/0181 (20130101)

Electric Digital Data Processing
G06F 1/163 (20130101)
G06F 3/01 (20130101)
G06F 3/011 (20130101)
G06F 3/04817 (20130101)
G06F 11/00 (20130101)

Image Data Processing or Generation, in General
G06T 5/20 (20130101)
G06T 7/33 (20170101) Original (OR) Class
G06T 11/00 (20130101)
G06T 19/006 (20130101)
G06T 2200/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304263 Martin et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Charles E. Martin (Westlake Village, California);  Tsai-Ching Lu (Thousand Oaks, California);  Alice A. Murphy (Mesa, Arizona);  Christopher R. Wezdenko (Mesa, Arizona);  Steve Slaughter (Scottsdale, Arizona)
ABSTRACT A method for determining a vehicle system prognosis includes detecting a predetermined characteristic of a vehicle with one or more sensors, obtaining a plurality of sensor signals corresponding to the predetermined characteristic, receiving the plurality of sensor signals from the one or more sensors and determining an input time series of data based on the sensor signals, generating, a matrix of time series data based on the input time series of data, clustering the matrix of time series data based on predetermined clustering criteria into a predetermined number of clusters, generating a sparse temporal matrix based on the predetermined number of clusters, extracting extracted features that are indicative of an operation of a vehicle system from the sparse temporal matrix and determining an operational status of the vehicle system based on the extracted features, and communicating the operational status of the vehicle system to an operator or crew member of the vehicle.
FILED Tuesday, December 13, 2016
APPL NO 15/377532
ART UNIT 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/4628 (20130101)
G06K 9/6244 (20130101)

Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 5/08 (20130101)
G07C 5/085 (20130101)
G07C 5/0808 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304604 Lazarus et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Research Laboratory (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, DC, None)
INVENTOR(S) Nathan S. Lazarus (Bethesda, Maryland);  Christopher D. Meyer (Bethesda, Maryland);  Iain M. Kierzewski (Silver Spring, Maryland)
ABSTRACT A deformable inductive device includes a magnetic core formed of an elastomer material having magnetic particles dispersed in it and at least one deformable electrode. Depending on the device's configuration, the deformable element may be embedded in, attached to, or in close proximity with the magnetic core. In some embodiments, the deformable inductive device may be configured as an inductor, solenoid, or transformer and the deformable electrode is at least partially embedded in the magnetic core, for instance. In another embodiment, the deformable inductive device may be configured as part of a wireless power transfer system which includes a coil and a magnetic backplane having the magnetic core with the coil being attached to or in close proximity to the magnetic backplane.
FILED Tuesday, May 03, 2016
APPL NO 15/144995
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/26 (20130101)
H01F 3/08 (20130101) Original (OR) Class
H01F 5/00 (20130101)
H01F 27/365 (20130101)
H01F 38/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304650 Youngner
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S) Daniel Youngner (Maple Grove, Minnesota)
ABSTRACT Apparatuses, systems, and methods for ion traps are described herein. One apparatus includes a number of microwave (MW) rails and a number of radio frequency (RF) rails formed with substantially parallel longitudinal axes and with substantially coplanar upper surfaces. The apparatus includes two sequences of direct current (DC) electrodes with each sequence formed to extend substantially parallel to the substantially parallel longitudinal axes of the MW rails and the RF rails. The apparatus further includes a number of through-silicon vias (TSVs) formed through a substrate of the ion trap and a trench capacitor formed in the substrate around at least one TSV.
FILED Tuesday, March 13, 2018
APPL NO 15/919959
ART UNIT 2881 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Computer Systems Based on Specific Computational Models
G06N 99/002 (20130101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 1/00 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 3/38 (20130101) Original (OR) Class
H01J 9/14 (20130101)
H01J 49/0018 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/945 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305014 Boukai et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Akram Boukai (Mountain View, California);  Yuri Bunimovich (Williamsville, New York);  William A. Goddard (Pasadena, California);  James R. Heath (South Pasadena, California);  Jamil Tahir-Kheli (Los Angeles, California)
ABSTRACT Methods and devices for controlling thermal conductivity and thermoelectric power of semiconductor nanowires are described. The thermal conductivity and the thermoelectric power are controlled substantially independently of the electrical conductivity of the nanowires by controlling dimensions and doping, respectively, of the nanowires. A thermoelectric device comprising p-doped and n-doped semiconductor nanowire thermocouples is also shown, together with a method to fabricate alternately p-doped and n-doped arrays of silicon nanowires.
FILED Tuesday, October 27, 2015
APPL NO 14/924596
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/26 (20130101) Original (OR) Class
H01L 35/32 (20130101)
H01L 35/34 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305158 Sherrer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Nuvotronics, Inc. (Radford, Virginia)
ASSIGNEE(S) CUBIC CORPORATION (San Diego, California)
INVENTOR(S) David Sherrer (Cary, North Carolina);  Jean-Marc Rollin (Chapel Hill, North Carolina);  Kenneth Vanhille (Cary, North Carolina);  Marcus Oliver (Durham, North Carolina);  Steven E. Huettner (Tucson, Arizona)
ABSTRACT An apparatus comprising a first power combiner/divider network and a second power combiner/divider network. The first power combiner/divider network splits a first electromagnetic signal into split signals that are connectable to signal processor(s). The second power combiner/divider network combines processed signals into a second electromagnetic signal. The apparatus includes a three-dimensional coaxial microstructure.
FILED Friday, November 10, 2017
APPL NO 15/809701
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 3/06 (20130101)
H01P 5/12 (20130101) Original (OR) Class
H01P 5/183 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305159 Sikora et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Paul A. Sikora (Holland Patent, New York);  Mark A. Southcott (Rome, New York)
ABSTRACT The invention provides an apparatus comprising a wide bandwidth resonating structure based on a primary split ring resonator having a plurality of additional split ring resonators bounded by the primary split ring resonator. The invention provides a method for optimizing the placement and size of the additional split ring resonators to achieve the desired bandwidth for the overall resonator structure.
FILED Tuesday, August 22, 2017
APPL NO 15/682648
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 7/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305161 Carr et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S) James A. Carr (Fountain View, California);  Mark B. Hanna (Allen, Texas)
ABSTRACT A dual stacked stripline circulator includes multiple composite ferrite discs, each having an inner portion and an outer portion; a first substrate having an edge with a first composite ferrite disc disposed in the first substrate; a second substrate having an edge with a second composite ferrite disc disposed in the second substrate; a third substrate having an edge with a third composite ferrite disc disposed in the third substrate, the third substrate disposed adjacent the second substrate; a fourth substrate having an edge with a fourth composite ferrite disc disposed in the fourth substrate; a first pattern defining three ports of a first three-port circulator disposed between the first substrate and the second substrate; a second pattern defining three ports of a second three-port circulator disposed between the third substrate and the fourth substrate; and a metal film encircling the edge of the first, second, third and fourth substrate.
FILED Tuesday, August 11, 2015
APPL NO 14/823266
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 1/387 (20130101)
H01P 11/003 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 29/49016 (20150115)
Y10T 29/49018 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305241 Small
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Scott L. Small (Newberry, Indiana)
ABSTRACT An illustrative cable connector hand tool and associated method are operable to permit cable connection sections to respectively pass through a side opening of hand tool members into a center aperture of the tool members. In one illustrative embodiment, the hand tool members are formed with a recessed portion adapted to receive an end of one of a pair of cable connectors such that mating edges of the cable connectors used to couple the cable connection sections are visible when the cable connectors are in a coupled configuration abutting each other. An illustrative embodiment includes the recessed portion formed with a plurality of keyway indentions or recesses spaced apart in the center aperture that are operable to engage keys, protrusions, or lugs on an outer wall of the cable connectors.
FILED Friday, February 03, 2017
APPL NO 15/423827
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding
B25B 13/04 (20130101)
B25B 13/50 (20130101)
B25B 13/481 (20130101)
B25B 23/0085 (20130101)

Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 13/622 (20130101)
H01R 13/6392 (20130101)
H01R 43/26 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 29/49 (20150115)
Y10T 29/4978 (20150115)
Y10T 29/49194 (20150115)
Y10T 29/53209 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305253 Shtyrkova et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Katia Shtyrkova (Arlington, Massachusetts);  Erich P. Ippen (Belmont, Massachusetts);  Franz X. Kaertner (Hamburg, Germany);  Patrick T. Callahan (Cambridge, Massachusetts);  Michael R. Watts (Hingham, Massachusetts)
ABSTRACT An artificial saturable absorber uses additive pulse mode-locking to enable pulse operation of an on-chip laser operation. Four different artificial saturable absorbers are disclosed. The first includes an integrated coupler, two arms each containing some implementation of the end-reflector, and a phase bias element in one arm. The second includes an integrated directional coupler, two integrated waveguide arms, and another integrated coupler as an output. The third includes an integrated birefringent element, integrated birefringent-free waveguide, and integrated polarizer. And the fourth includes a multimode waveguide that allows for different modes to propagate in such a way that the difference in the spatial distribution of intensity causes a nonlinear phase difference between the modes. These are just some examples of an on-chip fully integrated artificial saturable absorber with instantaneous recovery time that allow for generation of sub-femtosecond optical pulses at high repetition rates using passive mode-locking.
FILED Thursday, May 11, 2017
APPL NO 15/592905
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/082 (20130101)
H01S 3/0637 (20130101)
H01S 3/1112 (20130101)
H01S 3/1616 (20130101)
H01S 3/1636 (20130101)
H01S 3/08054 (20130101)
H01S 5/026 (20130101)
H01S 5/041 (20130101)
H01S 5/042 (20130101)
H01S 5/0604 (20130101)
H01S 5/0651 (20130101)
H01S 5/0657 (20130101) Original (OR) Class
H01S 5/1007 (20130101)
H01S 5/02453 (20130101)
H01S 5/06236 (20130101)
H01S 5/06246 (20130101)
H01S 5/06251 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305408 Sudhoff et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West LaFayette, Indiana)
INVENTOR(S) Scott Sudhoff (West Lafayette, Indiana);  Steve Pekarek (West Lafayette, Indiana);  Omar Abdul Laldin (Inglewood, California)
ABSTRACT A hybrid electrical machine containing surface mounted magnets which includes a magnetically permeable cylindrically shaped stator assembly having at least one stator winding formed about a plurality of stator teeth, a rotor assembly concentrically disposed within the stator assembly, including a magnetically permeable rotor backiron, a rotational drive mechanism coupled to the rotor backiron, and a plurality of protruding rotor poles, each including a magnetically permeable pole support assembly, a winding provided around the pole support assembly, and a radially magnetized permanent magnet assembly disposed about the pole support assembly.
FILED Monday, June 18, 2018
APPL NO 16/011119
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Dynamo-electric Machines
H02K 16/02 (20130101)
H02K 21/042 (20130101)

Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils
H02P 9/14 (20130101)
H02P 23/009 (20130101) Original (OR) Class
H02P 25/022 (20130101)
H02P 25/024 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305492 Martin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) RAYTHEON COMPANY (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Andrew L. Martin (Waltham, Massachusetts);  David W. Palmer (Waltham, Massachusetts)
ABSTRACT The frequency of a clock signal is compared to a predetermined range. If the measured frequency is outside the range, a system controller determines if a current operating state of the overall system allows for the internal clock to be adjusted back into compliance. If the controller determines that the current system state allows for the change, then a control signal to the internal clock signal source is changed by the smallest increment available, either to increase or decrease the frequency. If the internal clock signal is out of the desired range, and the system controller does not decide to modify the frequency, the controller may increase the size of the range by decreasing the lower bound and/or increasing the upper bound.
FILED Wednesday, July 12, 2017
APPL NO 15/647993
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Electric Digital Data Processing
G06F 1/04 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/06 (20130101) Original (OR) Class

Multiplex Communication
H04J 3/07 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/2657 (20130101)
H04L 27/2675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305587 Torres et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Myra Torres (Pittsford, New York);  Michael J. Moore (Rochester, New York);  Jeremy W. Sheaffer (Pittsford, New York);  Brian Drost (Fairport, New York);  Maksim Bobrov (Rochester, New York)
ABSTRACT A system and method of condition based maintenance of a fiber network includes a processor and memory having instructions that when executed cause the system to transmit an optical signal over a plurality of fiber links in the fiber network; receive a response signal in response to the transmitting of the optical signal; and determine one or more condition indicators in response to the receiving of the response signal.
FILED Friday, March 06, 2015
APPL NO 15/310036
ART UNIT 2633 — Digital Communications
CURRENT CPC
Transmission
H04B 10/071 (20130101)
H04B 10/0771 (20130101) Original (OR) Class
H04B 10/2504 (20130101)
H04B 10/07953 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305598 Devgan
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Preetpaul S Devgan (Dayton, Ohio)
ABSTRACT A method and apparatus for isolating an RF signal are provided. A first RF signal is received and passed to an input of a 90 degree hybrid. An output of the 90 degree hybrid is connected to a first waveguide and a second output is connected to a second waveguide of an optical modulator. A second RF signal is received and passed to an input of a second 90 degree hybrid. An output of the second 90 degree hybrid is connected to the second waveguide and a second output is connected to the first waveguide of the optical modulator. The optical modulator is biased to produce single side band optical outputs of the RF signals. The single side band optical outputs are passed to an optical notch filter to remove one of the side band outputs. The other of the side band optical outputs is converted to an electrical signal.
FILED Wednesday, November 25, 2015
APPL NO 14/951673
ART UNIT 2637 — Optical Communications
CURRENT CPC
Transmission
H04B 10/00 (20130101)
H04B 10/802 (20130101)
H04B 10/5165 (20130101) Original (OR) Class
H04B 10/5563 (20130101)
H04B 2210/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305622 Antonik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY SECRETARY OF THE AIR FORCE (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Paul Antonik (Rome, New York);  John D. Matyjas (Rome, New York);  Michael C. Wicks (Utica, New York)
ABSTRACT A system for transmitting a message, including an array of signal radiating elements for broadcasting signals that are unique one from another. One each of the unique signals is associated with one each of the radiating elements. One each of a set of transmitters is in electronic communication with one each of the radiating elements, and provides the associated unique signal to each of the radiating elements. A signal generating device receives the message from a message source and transforms the message into the unique signals. The unique signals, when broadcast, spatially interfere one with another such that the message is intelligibly receivable at only one location that is predetermined by the signal generating device, and is garbled at all other locations.
FILED Wednesday, May 10, 2017
APPL NO 15/592096
ART UNIT 2633 — Digital Communications
CURRENT CPC
Transmission
H04B 7/0413 (20130101)
H04B 7/0613 (20130101)

Secret Communication; Jamming of Communication
H04K 1/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305692 Peterson
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Medtronic, Inc. (Minneapolis, Minnesota)
ASSIGNEE(S) Medtronic, Inc. (Minneapolis, Minnesota)
INVENTOR(S) Erik J. Peterson (Fridley, Minnesota)
ABSTRACT In one example, a method includes transitioning, responsive to determining that a charging coil of wireless charger is in proximity of an implantable medical device (IMD) and by the IMD, from operating in a non-pairing mode into a pairing mode of a far-field wireless communication protocol. In this example, operating in the paring mode comprises: receiving, by the IMD and via a transceiver of the far-field wireless communication protocol, a public encryption key from another device that is different than the wireless charger; and determining, based on the public encryption key of the other device and a public encryption key of the IMD, a link encryption key for future communication between the IMD and the other device. In this example, the method further includes communicating, by the IMD and based on the link encryption key, with the other device via the far-field wireless communication protocol.
FILED Wednesday, February 22, 2017
APPL NO 15/439503
ART UNIT 2435 — Cryptography and Security
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 31/002 (20130101)
A61M 2205/3523 (20130101)
A61M 2205/8206 (20130101)
A61M 2205/8243 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/3605 (20130101)
A61N 1/3787 (20130101)
A61N 1/37223 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/14 (20130101)
H04L 9/30 (20130101)
H04L 9/3236 (20130101) Original (OR) Class
H04L 2209/80 (20130101)
H04L 2209/88 (20130101)

Wireless Communication Networks
H04W 4/80 (20180201)
H04W 76/10 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305805 Flajslik et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Mario Flajslik (Hudson, Massachusetts);  Eric R. Borch (Fort Collins, Colorado);  Michael A. Parker (Santa Clara, California)
ABSTRACT Technologies for adaptive routing based on aggregated congestion information include a network switch that includes a plurality of output ports. The network switch is configured to determine a maximum local occupancy count for each output port based on a maximum local occupancy count of output buffer queues of each output port, a local congestion value based on the maximum local occupancy count, and a remote congestion value for a corresponding remote input buffer queue of a remote computing device communicatively coupled to a corresponding output port. The network switch is further configured to determine, for each output port, a total congestion value as a function of the local congestion value and the remote congestion value and enqueue the network packet into one of the output buffer queues of one of the output ports based on the total congestion values of the output ports. Other embodiments are described herein.
FILED Friday, July 01, 2016
APPL NO 15/200442
ART UNIT 2412 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 47/11 (20130101)
H04L 47/30 (20130101)
H04L 47/125 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305870 Khazan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Roger I. Khazan (Arlington, Massachusetts);  Joshua Kramer (Burlington, Massachusetts);  Daniil M. Utin (Waban, Massachusetts);  Mankuan Michael Vai (Sudbury, Massachusetts);  David Whelihan (Framingham, Massachusetts)
ABSTRACT A method for operating a secure device having a plurality of mutually exclusive circuit zones, including a first circuit zone having a first level of security and a second circuit zone having a second level of security less than the first level of security, the method including unpacking a key exchange package including receiving a key exchange package in the second circuit zone, the key exchange package including encrypted key data and processing the encrypted key data using a content key in the first circuit zone to generate decrypted key data and storing the decrypted key data in the first circuit zone without disclosing the decrypted key data into the second circuit zone.
FILED Monday, June 08, 2015
APPL NO 14/733325
ART UNIT 2495 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/602 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/14 (20130101)
H04L 9/0819 (20130101)
H04L 9/0894 (20130101)
H04L 63/20 (20130101)
H04L 63/061 (20130101) Original (OR) Class
H04L 63/126 (20130101)
H04L 63/0428 (20130101)
H04L 2209/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305919 Locasto et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Michael E. Locasto (Springfield, Virginia);  Salvatore J. Stolfo (New York, New York);  Angelos D. Keromytis (New York, New York);  Ke Wang (New York, New York)
ABSTRACT In accordance with some embodiments of the present invention, systems and methods that protect an application from attacks are provided. In some embodiments of the present invention, input from an input source, such as traffic from a communication network, can be routed through a filtering proxy that includes one or more filters, classifiers, and/or detectors. In response to the input passing through the filtering proxy to the application, a supervision framework monitors the input for attacks (e.g., code injection attacks). The supervision framework can provide feedback to tune the components of the filtering proxy.
FILED Monday, May 09, 2016
APPL NO 15/149821
ART UNIT 2438 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/41 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/0815 (20130101)
H04L 63/1408 (20130101)
H04L 63/1416 (20130101) Original (OR) Class
H04L 63/1441 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305921 Gao et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Jing Gao (Buffalo, New York);  Deepak Turaga (Yorktown Heights, New York);  Long H. Vu (Yorktown Heights, New York);  Houping Xiao (Buffalo, New York)
ABSTRACT A network security apparatus includes a packet detector detecting transmission of data packets between a plurality of hosts and a plurality of domains and defining a plurality of links therefrom. A model builder circuit receives the plurality of links from the packet detector, receives ground truth information labeling one or more of the plurality of hosts or one or more of the plurality of domains as benign or malicious, generates predictive models from the received links and ground truth information, and stores generated predictive models in a predictive model database. An anomaly detector circuit retrieves the generated predictive models from the predictive model database and uses the predictive models to label each of the plurality of hosts and plurality of domains, that have not previously been labeled by the ground truth information, as benign or malicious.
FILED Thursday, April 28, 2016
APPL NO 15/141127
ART UNIT 2494 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/552 (20130101)
G06F 21/577 (20130101)

Computer Systems Based on Specific Computational Models
G06N 99/00 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 43/12 (20130101)
H04L 43/062 (20130101)
H04L 63/0227 (20130101)
H04L 63/1425 (20130101) Original (OR) Class
H04L 63/1433 (20130101)
H04L 63/1466 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305945 Ethier et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
National Security Engineering Center (NSEC)
Federally Funded Research and Development Center (FFRDC)
Operated by MITRE Corporation (MITRE) at Bedford, MA
APPLICANT(S) THE MITRE CORPORATION (McLean, Virginia)
ASSIGNEE(S) The MITRE Corporation (McLean, Virginia)
INVENTOR(S) Randall Paul Joseph Ethier (Burke, Virginia);  Gene Lee Harrison (Leesburg, Virginia)
ABSTRACT Disclosed herein are system, apparatus, method and/or computer program product embodiments for providing survivable calling and conferencing. An embodiment operates by providing, by a first server, a first sub-conference to a plurality of user devices over first lines. The first sub-conference is combined with a second sub-conference to form a collective conference of the plurality of user devices. The first server accesses the conference. A second server is configured to provide the second sub-conference of the collective conference to the plurality of user devices over second lines, the first and second lines being distinct from each other. The collective conference may provide resilient and reliable sharing of information among participants and may leverage dispersed elements or diverse links simultaneously without impediments of echoes, loops, or other impacts.
FILED Monday, November 10, 2014
APPL NO 14/537641
ART UNIT 2454 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 65/403 (20130101) Original (OR) Class
H04L 67/10 (20130101)
H04L 69/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10306186 Chuang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Daniel B. Chuang (Cambridge, Massachusetts);  Lawrence M. Candell (Arlington, Massachusetts);  William D. Ross (Westford, Massachusetts);  Mark E. Beattie (Westford, Massachusetts);  Cindy Y. Fang (Arlington, Massachusetts);  Bobby Ren (Cambridge, Massachusetts);  Jonathan P. Blanchard (Sterling, Massachusetts);  Gary M. Long, Jr. (Lowell, Massachusetts);  Lauren L. White (Burlington, Massachusetts);  Svetlana V. Panasyuk (Lexington, Massachusetts);  Mark Bury (Acton, Massachusetts)
ABSTRACT Security guards at large facilities, such as airports, monitor multiple screens that display images from individual surveillance cameras dispersed throughout the facility. If a guard zooms with a particular camera, he may lose image resolution, along with perspective on the surrounding area. Embodiments of the inventive Imaging System for Immersive Surveillance (ISIS) solve these problems by combining multiple cameras in one device. When properly mounted, example ISIS systems offer up to 360-degree, 240-megapixel views on a single screen. (Other fields of view and resolutions are also possible.) Image-stitching software merges multiple video feeds into one scene. The system also allows operators to tag and follow targets, and can monitor restricted areas and sound an alert when intruders breach them.
FILED Thursday, March 05, 2015
APPL NO 14/639244
ART UNIT 2488 — Recording and Compression
CURRENT CPC
Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 13/1968 (20130101)
G08B 13/19608 (20130101)
G08B 13/19619 (20130101)
G08B 13/19628 (20130101)
G08B 13/19682 (20130101)

Pictorial Communication, e.g Television
H04N 5/247 (20130101)
H04N 5/3415 (20130101)
H04N 5/23238 (20130101)
H04N 7/181 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10306267 Lin et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Chung-Ching Lin (White Plains, New York);  Sharathchandra U. Pankanti (Darien, Connecticut);  John R. Smith (New York, New York)
ABSTRACT A compression system for compressing a video received from an imaging device, the compression system including a transformation estimation device configured to estimate, based on pixel transformations between a first frame and a second frame of the video, a transformation matrix, an encoding device configured to encode the second frame as an increment with the first frame based on the transformation matrix generated by the transformation device, a compression device configured to compress the increments into compressed data, and a reconstruction device configured to reconstruct the first frame and the second frame using the transformation matrix generated by the transformation estimation device.
FILED Monday, August 31, 2015
APPL NO 14/840140
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6211 (20130101)

Image Data Processing or Generation, in General
G06T 9/004 (20130101)

Pictorial Communication, e.g Television
H04N 5/265 (20130101)
H04N 5/23238 (20130101)
H04N 19/60 (20141101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10306396 Romigh
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Griffin D. Romigh (Dayton, Ohio)
ABSTRACT An improved methodology for binaural rendering of audio signals that are perceived by a user to originate from a real-world spatial location is disclosed. Embodiments enable personalized HRTF selection from among a data store containing a plurality of candidate HRTFs using an evaluation-based personalization strategy. One or more relational models personalize the selection. These relational models can relate candidate HRTFs to each other and a particular user to other users so that only a subset of the candidate HRTFs require evaluation. Candidate HRTFs can be evaluated according to one or more selection policies, and relational models can be updated based on actual responses from a user to virtual audio signals that are rendered by a candidate HRTF.
FILED Thursday, April 19, 2018
APPL NO 15/957876
ART UNIT 2652 — Videophones and Telephonic Communications
CURRENT CPC
Stereophonic Systems
H04S 3/008 (20130101)
H04S 7/303 (20130101) Original (OR) Class
H04S 2420/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10306751 Duffy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S) HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina)
INVENTOR(S) Jason C. Duffy (Granby, Connecticut);  James A. Gosse (Storrs, Connecticut);  Shun-Tien Lin (Glastonbury, Connecticut);  Michael Maynard (Somers, Connecticut);  An Nguyen (East Hartford, Connecticut)
ABSTRACT An electronic module assembly has a memory module that includes a memory module and an electronic module. The memory module includes a first board having a first board first surface disposed opposite a first board second surface. The electronic module is operatively connected to the memory module. The electronic module includes a mounting plate having a mounting plate first surface that is disposed opposite a mounting plate second surface that faces towards the first board first surface. The mounting plate has a first post and a second post spaced apart from the first post.
FILED Friday, October 20, 2017
APPL NO 15/788862
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 12/716 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/144 (20130101)
H05K 1/181 (20130101)
H05K 1/0201 (20130101)
H05K 1/0271 (20130101) Original (OR) Class
H05K 2201/042 (20130101)
H05K 2201/049 (20130101)
H05K 2201/068 (20130101)
H05K 2201/09063 (20130101)
H05K 2201/10159 (20130101)
H05K 2201/10189 (20130101)
H05K 2201/10325 (20130101)
H05K 2201/10409 (20130101)
H05K 2201/10522 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10306801 Chainer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Timothy Joseph Chainer (Putnam Valley, New York);  Pritish Ranjan Parida (Stamford, Connecticut);  Fanghao Yang (Somerset, New Jersey)
ABSTRACT Techniques that facilitate two-phase liquid cooling of an electronic device are provided. In one example, an apparatus, such as a cold plate device, comprises a first stackable layer and a second stackable layer. The first stackable layer comprises a first channel formed within the first stackable layer. The first channel comprises a first channel width and the first channel receives a coolant fluid via an inlet port of the apparatus. The second stackable layer comprises a second channel that provides a path for the coolant fluid to flow between the first channel and an outlet port of the apparatus. A width of the second channel increases along a flow direction of the coolant fluid that flows between the inlet port and the outlet port.
FILED Thursday, March 29, 2018
APPL NO 15/939777
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 3/12 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/4882 (20130101)
H01L 23/473 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/20254 (20130101) Original (OR) Class
H05K 7/20272 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10306802 Ditri et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Lockheed Martin Corporation (Bethesda, Maryland)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) John Ditri (Huntingdon Valley, Pennsylvania);  Joseph W. Hahn (Erial, New Jersey);  Michael K. McNulty (Cherry Hill, New Jersey)
ABSTRACT A heat sink for cooling an integrated circuit device includes a body having a first side and a second side. A fluid inlet opening is formed in the second side of the body for receiving pressurized fluid from a fluid source. A plurality of impingement openings are formed in the first side of the body. At least one fluid delivery channel is provided and configured to deliver pressurized fluid from the fluid inlet opening to the plurality of impingement openings for generating a plurality of fluid streams expelled from the plurality of impingement openings. A plurality of fluid diverters are formed on the first side of the body and arranged generally between each of the plurality of impingement openings for diverting a flow of fluid around each of the plurality of impingement openings.
FILED Wednesday, December 02, 2015
APPL NO 14/957011
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/20263 (20130101) Original (OR) Class
H05K 7/20272 (20130101)
H05K 7/20281 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US D849597 Kiel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Thomas J. Kiel (Bernardsville, New Jersey);  Kris J. Mayer (Blairstown, New Jersey)
ABSTRACT
FILED Tuesday, November 21, 2017
APPL NO 29/626867
ART UNIT 2914 — Design
CURRENT CPC
Transportation
D12/12
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 10299695 Muraskin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Jordan Muraskin (New York, New York);  Jason Sherwin (New York, New York);  Paul Sajda (New York, New York)
ABSTRACT Methods and systems for evaluating a subject's response to a task related to a stimulus include a brain activity sensor, such as an EEG sensor, for measuring neural data generated by the subject in response to the visual stimulus. One or more neural discriminators can be calculated based on the neural data. In order to generate one or more neural discriminators, two or more task conditions can be selected for discrimination. The subject's performance can be evaluated based on the one or more neural discriminators. Feedback can be provided to the subject to assist in achieving better performance.
FILED Monday, February 02, 2015
APPL NO 14/612233
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/0059 (20130101)
A61B 5/0075 (20130101)
A61B 5/0478 (20130101)
A61B 5/0482 (20130101)
A61B 5/742 (20130101)
A61B 5/04012 (20130101)
A61B 5/04842 (20130101) Original (OR) Class
A61B 2503/10 (20130101)
A61B 2576/026 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4806 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10299720 Brown et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
NIH Office of the Director (NIHOD)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Emery N. Brown (Brookline, Massachusetts);  Patrick L. Purdon (Somerville, Massachusetts)
ABSTRACT The present invention generally relates to compositions comprising anesthesia-reversing agents which facilitate or increase the time of awakening or reverse the effects of general anesthesia-induced unconsciousness. In some embodiments, the anesthesia reversing agent can be selected from any or a combination of methylphenidate (MPH), amphetamine, modafinil, amantadine, caffeine, or analogs or derivatives thereof. In some embodiments, compositions comprising at least one or more anesthesia-reversing agents can be used to facilitate awakening from anesthesia without or decreasing occurrence of delirium, and can be used in methods to treat or prevent the symptoms associated with emergence delirium, as well as treat a subject oversedated with general an esthesia. The invention also relates to methods for administering these compositions comprising anesthesia-reversing agents to subjects and for use.
FILED Tuesday, February 10, 2015
APPL NO 14/618978
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0476 (20130101)
A61B 5/04012 (20130101)
A61B 5/4821 (20130101) Original (OR) Class

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/13 (20130101)
A61K 31/137 (20130101)
A61K 31/165 (20130101)
A61K 31/522 (20130101)
A61K 31/4458 (20130101)
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10299736 Najafi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Bijan Najafi (Tucson, Arizona);  Saman Parvaneh (Tucson, Arizona);  Martha Jane Mohler (Tucson, Arizona);  David G. Armstrong (Tucson, Arizona);  Mindy Joy Fain (Tucson, Arizona);  Marvin J. Slepian (Tucson, Arizona)
ABSTRACT Methods, devices, and systems according to present principles provide ways to diagnose frailty and assess the severity of its clinical status—e.g., non-frail, pre-frail, and frail, especially as measured and quantified during activities of daily living. Systems and methods according to present principles objectively quantify physical activity behaviors and identify specific motor tasks, which indicate clinical frailty syndrome behaviors such as flopping, cautious-sitting, non-uniform walking fluctuations, cognitive decline, slowness, weakness, and exhaustion. Additionally, the systems and methods allow improved sensitivity and specificity of frailty identification by further assessing physiological parameters such as heart rate, respiration rate, and skin temperature in response to, or recovery from, specific activities.
FILED Friday, March 27, 2015
APPL NO 14/671980
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0002 (20130101)
A61B 5/112 (20130101)
A61B 5/0816 (20130101)
A61B 5/1116 (20130101)
A61B 5/1118 (20130101)
A61B 5/1123 (20130101)
A61B 5/02405 (20130101)
A61B 5/7275 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300023 Karp et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Jeffrey M. Karp (Cambridge, Massachusetts);  Nitin Joshi (Cambridge, Massachusetts);  Nikken Wiradharma (Cambridge, Massachusetts);  Kai Vincent Slaughter (Cambridge, Massachusetts)
ABSTRACT A non-covalently assembled hydrogel or organo-gel composition with serum stability is described. Low molecular weight (<2,500 Da), generally regarded as safe (GRAS), materials assemble in the presence of a stabilizing agent at an appropriate molar percentage, forming hydrogel or organo-gel with nanostructures that resist disassembly or destabilization in serum for an extended period of time. The composition is used to deliver one or more therapeutic, prophylactic, or diagnostic agents, allowing for controlled release in response to biological stimuli such as enzymes and a greatly improved dosing efficacy.
FILED Friday, April 27, 2018
APPL NO 15/965499
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/5123 (20130101) Original (OR) Class
A61K 31/337 (20130101)
A61K 49/0093 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300037 Dalton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Child Health and Human Development (NICHD)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S) UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee)
INVENTOR(S) James T. Dalton (Ann Arbor, Michigan);  Thamarai Ponnusamy (Memphis, Tennessee);  Ramesh Narayanan (Cordova, Tennessee)
ABSTRACT This invention is directed to substituted acylanilide compounds and uses thereof in treating muscular dystrophies such as Duchenne muscular dystrophy and Becker muscular dystrophy and in improving or preserving lung function and cardiac function in a subject suffering from Duchenne muscular dystrophy.
FILED Wednesday, October 18, 2017
APPL NO 15/786811
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/277 (20130101) Original (OR) Class
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300043 Kashyap et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Purna C. Kashyap (Rochester, Minnesota);  Michael Fischbach (Portola Valley, California)
ABSTRACT This document provides materials and methods related to bacterial compositions containing at least one bacterial organism having tryptophan decarboxylase activity. For example, bacterial compositions containing at least one bacterial organism having tryptophan decarboxylase activity and methods for using such bacterial compositions to improve gastrointestinal epithelial function and/or to treat gastrointestinal disorders are provided.
FILED Friday, August 12, 2016
APPL NO 15/235782
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/405 (20130101) Original (OR) Class
A61K 31/405 (20130101)
A61K 35/74 (20130101)
A61K 35/741 (20130101)
A61K 35/742 (20130101)
A61K 2035/115 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300069 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
ASSIGNEE(S) Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
INVENTOR(S) Binghe Wang (Marietta, Georgia);  Danzhu Wang (Atlanta, Georgia);  Xingyue Ji (Atlanta, Georgia);  Alexander Draganov (Atlanta, Georgia);  Chaofeng Dai (Atlanta, Georgia);  Krishna Damera (Smyrna, Georgia);  Didier Merlin (Decatur, Georgia);  Emilie Viennois (Atlanta, Georgia);  Yueqin Zheng (Atlanta, Georgia)
ABSTRACT Carbon monoxide-releasing organic molecules are described herein. The molecules can be synthesized prior to administration (e.g., ex vivo) or formed in vivo. In those embodiments where the molecules are formed in vivo, reactants are administered under physiological conditions and undergo a cycloaddition reaction to form a product which releases carbon monoxide. In applying such reactions for therapeutic applications in vivo, the cycloaddition and CO release typically occur only under near-physiological or physiological conditions. For example, in some embodiments, the cycloaddition reaction and/or release of carbon monoxide occur at a temperature of about 37 C and pH of about 7.4. Pharmaceutical compositions and methods for release carbon monoxide are also described.
FILED Tuesday, June 09, 2015
APPL NO 15/317705
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/015 (20130101)
A61K 31/015 (20130101)
A61K 31/122 (20130101)
A61K 31/122 (20130101)
A61K 31/166 (20130101)
A61K 31/216 (20130101)
A61K 31/216 (20130101)
A61K 31/235 (20130101)
A61K 31/5375 (20130101) Original (OR) Class
A61K 47/61 (20170801)
A61K 47/549 (20170801)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/40 (20170801)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 37/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300070 Goldman et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Aaron Goldman (Somerville, Massachusetts);  Shiladitya Sengupta (Waltham, Massachusetts);  Abhimanyu Paraskar (Belmont, Massachusetts)
ABSTRACT Described are combination therapies and metabolically-activated drug conjugates and their use in treating cancer in subjects.
FILED Friday, March 27, 2015
APPL NO 15/127973
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/704 (20130101)
A61K 31/704 (20130101)
A61K 31/5377 (20130101) Original (OR) Class
A61K 31/5377 (20130101)
A61K 31/7068 (20130101)
A61K 31/7068 (20130101)
A61K 45/06 (20130101)
A61K 47/55 (20170801)
A61K 47/556 (20170801)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300073 Haudenschild et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Dominik Haudenschild (Davis, California);  Jasper Yik (Elk Grove, California)
ABSTRACT Provided are methods for the combined use of cyclin-dependent kinase 9 (CDK9) inhibitors and bromodomain containing 4 (BRD4) inhibitors to reduce, inhibit and/or prevent cartilage degradation and systemic traumatic inflammation. A combination of CDK9 inhibitors and BRD4 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. A combination of CDK9 inhibitors and BRD4 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
FILED Tuesday, October 13, 2015
APPL NO 15/517476
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/352 (20130101)
A61K 31/352 (20130101)
A61K 31/445 (20130101)
A61K 31/551 (20130101)
A61K 31/551 (20130101)
A61K 31/5513 (20130101) Original (OR) Class
A61K 31/5513 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300074 Pache et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Sanford-Burnham Medical Research Institute (La Jolla, California);  Salk Institute for Biological Studies (La Jolla, California)
ASSIGNEE(S) SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California);  SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California)
INVENTOR(S) Lars Pache (La Jolla, California);  Sumit K. Chanda (La Jolla, California);  Mitchell Dennis Vamos (La Jolla, California);  Nicholas David Peter Cosford (La Jolla, California);  Peter Teriete (La Jolla, California);  John Marlett (La Jolla, California);  Arturo Diaz (La Jolla, California);  John A. T. Young (La Jolla, California)
ABSTRACT Provided herein is the use of compounds that modulate the activity of inhibitor of apoptosis proteins (IAPs), alone or in combination with other therapeutic agents, in the treatment of human immunodeficiency virus (HIV). Described herein is the use of IAP antagonists in the treatment of human immunodeficiency virus (HIV) in a mammal, alone or in combination with other therapeutic agents used in HIV therapy. In one aspect, provided herein is a method of treating human immunodeficiency virus (HIV) in an individual in need thereof comprising administering a therapeutically effective amount of at least one inhibitor of apoptosis proteins (IAP) antagonist.
FILED Thursday, June 04, 2015
APPL NO 15/313286
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/18 (20130101)
A61K 31/18 (20130101)
A61K 31/20 (20130101)
A61K 31/20 (20130101)
A61K 31/27 (20130101)
A61K 31/27 (20130101)
A61K 31/55 (20130101)
A61K 31/167 (20130101)
A61K 31/167 (20130101)
A61K 31/551 (20130101)
A61K 31/553 (20130101) Original (OR) Class
A61K 31/553 (20130101)
A61K 31/554 (20130101)
A61K 31/554 (20130101)
A61K 31/4045 (20130101)
A61K 31/4045 (20130101)
A61K 31/4406 (20130101)
A61K 31/4406 (20130101)
A61K 31/5365 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300076 Szmulewitz et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Russell Z. Szmulewitz (Chicago, Illinois);  Suzanne D. Conzen (Park Ridge, Illinois)
ABSTRACT Methods are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer may be one that has become resistant to androgen deprivation therapy, for example, by increase in glucocorticoid receptor expression and/or activity.
FILED Thursday, September 14, 2017
APPL NO 15/704726
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/437 (20130101)
A61K 31/437 (20130101)
A61K 31/567 (20130101) Original (OR) Class
A61K 31/567 (20130101)
A61K 31/569 (20130101)
A61K 31/569 (20130101)
A61K 31/573 (20130101)
A61K 31/573 (20130101)
A61K 31/4166 (20130101)
A61K 31/4166 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300080 Leis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Northwestern University (Evanston, Illinois);  The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  The Research Foundation for the State University (Albany, New York)
INVENTOR(S) Jonathan Leis (Chicago, Illinois);  Carol Carter (Huntington, New York)
ABSTRACT A compound having an antiviral activity for inhibiting release of an enveloped virus from a cell is disclosed, including methods of inhibiting release of an enveloped virus from a cell. The antiviral activity of the compound includes inhibiting formation of an associative complex or disrupting formation of an associative complex. The associative complex comprises an L-domain motif of the enveloped virus and at least one cellular polypeptide, or fragment thereof, capable of binding the L-domain motif of the enveloped virus.
FILED Tuesday, November 10, 2015
APPL NO 14/937182
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/53 (20130101)
A61K 31/65 (20130101) Original (OR) Class
A61K 31/165 (20130101)
A61K 31/415 (20130101)
A61K 31/437 (20130101)
A61K 31/4035 (20130101)
A61K 31/4439 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300082 Breuer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Christopher K. Breuer (New Albany, Ohio);  Tarek Fahmy (New Haven, Connecticut)
ABSTRACT A composition containing a macrophage inhibitor may be administered in an effective amount to prevent, inhibit or reduce restenosis, thrombus or aneurysm formation in implanted polymeric vascular grafts. The composition may be administered prior to vascular graft implantation, at the same time as vascular graft implantation, following vascular graft implantation, or any combination thereof. Examplary macrophage inhibitors include bisphosphonates, anti-folate drugs and antibodies, preferably in a controlled release or liposomal formulation.
FILED Wednesday, April 13, 2016
APPL NO 15/097716
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 9/7023 (20130101)
A61K 31/663 (20130101) Original (OR) Class

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101)
A61L 27/34 (20130101)
A61L 27/54 (20130101)
A61L 27/58 (20130101)
A61L 27/507 (20130101)
A61L 2300/62 (20130101)
A61L 2300/602 (20130101)
A61L 2300/622 (20130101)
A61L 2300/624 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300086 Machielse et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Vtesse Inc. (Hazelwood, Missouri)
ASSIGNEE(S) VTESSE INC (Hazelwood, Missouri)
INVENTOR(S) Bernardus Nicolaas Machielse (North Potomac, Maryland);  Allan Darling (North Potomac, Maryland)
ABSTRACT This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
FILED Tuesday, September 18, 2018
APPL NO 16/134028
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/08 (20130101)
A61K 9/0019 (20130101)
A61K 9/0085 (20130101)
A61K 31/724 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300091 McFetridge et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S) Peter S. McFetridge (Gainesville, Florida);  Marc C. Moore (Gainesville, Florida)
ABSTRACT The present disclosure provides compositions including a human placental extract and biodegradable microparticles, sustained release angiogenesis-modulating compositions, compositions and methods for releasing a placental extract to a target over a period of time, and methods for inducing and/or modulating angiogenesis and identifying modulators of angiogenesis. The present disclosure also provides methods of making a composition, including a placental extract that can induce and/or modulate angiogenesis.
FILED Thursday, May 07, 2015
APPL NO 15/309306
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1647 (20130101)
A61K 9/1658 (20130101)
A61K 35/50 (20130101) Original (OR) Class
A61K 38/18 (20130101)
A61K 38/19 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/54 (20130101)
A61L 27/3604 (20130101)
A61L 27/3683 (20130101)
A61L 27/3808 (20130101)
A61L 2300/252 (20130101)
A61L 2300/426 (20130101)
A61L 2300/602 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/069 (20130101)
C12N 5/0691 (20130101)
C12N 2502/28 (20130101)
C12N 2502/1347 (20130101)
C12N 2503/04 (20130101)
C12N 2533/92 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300095 Chiorini et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) John A. Chiorini (Dayton, Maryland);  Giovanni DiPasquale (Kensington, Maryland);  Edoardo Mannucci (Prato, Italy)
ABSTRACT The invention relates to a gene transfer-based method to protect a subject from diabetes or obesity. The method comprises administering to a salivary gland of the subject an AAV virion comprising an AAV vector that encodes an exendin-4 protein. Also provided are exendin-4 proteins and nucleic acid molecules that encode such exendin-4 proteins. Also provided are AAV vectors and AAV virions that encode an exendin-4 protein. One embodiment is an exendin-4 protein that is a fusion protein comprising an NGF secretory segment joined to the amino terminus of an exendin-4 protein domain.
FILED Monday, December 05, 2016
APPL NO 15/368940
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/76 (20130101) Original (OR) Class
A61K 35/761 (20130101)
A61K 38/1703 (20130101)
A61K 48/005 (20130101)
A61K 48/0075 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Peptides
C07K 14/48 (20130101)
C07K 14/605 (20130101)
C07K 14/57563 (20130101)
C07K 2319/50 (20130101)
C07K 2319/055 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/79 (20130101)
C12N 15/86 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300106 Levine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas);  Baylor College of Medicine (Houston, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Beth C. Levine (Dallas, Texas);  Sanae Shoji-Kawata (Dallas, Texas);  Nick V. Grishin (Dallas, Texas);  Lisa N. Kinch (Dallas, Texas);  Olivier Lichtarge (Houston, Texas);  Angela D. Wilkins (Houston, Texas)
ABSTRACT An autophagy-inducing compound comprises an autophagy-inducing peptide comprising Beclin 1 peptides immediately N- and C-terminally flanked by moieties R1 and R2, respectively, wherein up to six of said peptide residues may be substituted, R1 and R2 do not naturally flank the Beclin 1 residues, and F270 and F274 are optionally substituted and optionally linked. The compounds may be used to induce autophagy.
FILED Thursday, September 03, 2015
APPL NO 14/844007
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/08 (20130101) Original (OR) Class

Peptides
C07K 7/06 (20130101)
C07K 14/47 (20130101)
C07K 14/82 (20130101)
C07K 14/4747 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300107 Bayer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado)
INVENTOR(S) K. Ulrich Bayer (Denver, Colorado);  Steve Coultrap (Denver, Colorado)
ABSTRACT Embodiments herein generally relate to methods, compositions and uses of CaMKII inhibitors. Other embodiments relate to methods, compositions and uses of agents that target CaMKII. Yet further embodiments relate to compositions, methods and uses of CaMKIIN-derived molecules and other CaMKII inhibitor molecules that inhibit autonomous CaMKII activity. In accordance with these embodiments, compositions that inhibit autonomous CaMKII activity may be used for treating conditions causing neuronal cell death, for treating cancer or for treating neurodegenerative disorders.
FILED Thursday, September 14, 2017
APPL NO 15/704902
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/10 (20130101) Original (OR) Class
A61K 38/45 (20130101)
A61K 38/45 (20130101)
A61K 38/55 (20130101)
A61K 38/55 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1205 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300108 McPherson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) ASTUTE MEDICAL, INC. (San Diego, California);  UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Astute Medical, Inc. (San Diego, California);  University of Pittsburgh - of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Paul McPherson (Encinitas, California);  John A. Kellum (Pittsburgh, Pennsylvania)
ABSTRACT It is an object of the present invention to provide methods and compositions for protection of subjects from acute kidney injury by treating the subject with compounds that modulate the cell cycle. Modulating the cell cycle can comprise inducing G0/G1 cell cycle arrest, and/or inducing cell cycle progression. As demonstrated below, even a single administration of a compound which induces G0/G1 cell cycle arrest can protect subjects from AKI, and may be used prophylactically in advance of, or as a treatment following, various treatments or conditions that are known to be injurious to the kidney, followed optionally by release of the arrest. Once AKI is established, cell cycle progression can be induced to increase replacement of lost and damaged cells.
FILED Wednesday, December 03, 2014
APPL NO 15/101118
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/55 (20130101)
A61K 31/357 (20130101)
A61K 31/366 (20130101)
A61K 31/436 (20130101)
A61K 31/437 (20130101)
A61K 31/453 (20130101)
A61K 31/585 (20130101)
A61K 38/13 (20130101) Original (OR) Class
A61K 38/55 (20130101)
A61K 38/1754 (20130101)
A61K 45/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101)
G01N 2333/4745 (20130101)
G01N 2333/8146 (20130101)
G01N 2800/50 (20130101)
G01N 2800/347 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300115 Biragyn et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Arya Biragyn (Lutherville, Maryland);  Kouji Matsushima (Tokyo, Japan);  Dolgor Baatar (Parkville, Maryland)
ABSTRACT The instant invention provides methods and compositions for modulation of the immune system. Specifically, the present disclosure provides methods and compositions for increasing T cell mediated immune response useful in the treatment of cancer and chronic infection.
FILED Wednesday, January 11, 2017
APPL NO 15/404189
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/45 (20130101)
A61K 38/195 (20130101)
A61K 38/465 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 47/642 (20170801)
A61K 47/6415 (20170801)

Peptides
C07K 14/521 (20130101)
C07K 14/523 (20130101)
C07K 14/7158 (20130101)
C07K 2319/55 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/1077 (20130101)

Enzymes
C12Y 204/02036 (20130101)
C12Y 301/27 (20130101)
C12Y 301/27005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300117 Dubal
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Dena Dubal (Oakland, California)
ABSTRACT Provided herein are klotho polypeptide compositions and methods for improving cognitive function in an individual comprising treatment of with klotho polypeptides.
FILED Thursday, May 24, 2018
APPL NO 15/988216
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/47 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2402 (20130101)

Enzymes
C12Y 302/01031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300120 Edwards, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
U.S. Public Health Service (USPHS)
APPLICANT(S) Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center (Torrance, California)
ASSIGNEE(S) Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (Torrance, California)
INVENTOR(S) John E. Edwards, Jr. (Palos Verdes Estates, California);  Ashraf S. Ibrahim (Irvine, California);  Bradley J. Spellberg (Rancho Palos Verdes, California);  Yue Fu (Carson, California);  Scott G. Filler (Rancho Palos Verdes, California);  Michael R. Yeaman (Redondo Beach, California)
ABSTRACT The invention provides a vaccine including an isolated Als protein family member having cell adhesion activity, or an immunogenic fragment thereof, with an adjuvant in a pharmaceutically acceptable medium. The invention also provides a method of treating or preventing hematogenously disseminated or mucocutaneous candidiasis. The method includes administering an immunogenic amount of a vaccine an isolated Als protein family member having cell adhesion activity, or an immunogenic fragment thereof, in a pharmaceutically acceptable medium. A method of treating or preventing disseminated candidiasis also is provided that includes administering an effective amount of an isolated Als protein family member having cell adhesion activity, or an functional fragment thereof, to inhibit the binding or invasion of Candida to a host cell or tissue. The Als protein family member can be derived from a Candida strain selected from the group consisting of Candida albicans, Candida krusei, Candida tropicalis, Candida glabrata and Candida parapsilosis and the Als protein family member includes Als1p, Als3p, Als5p, Als6p, Als7p or Als9p. Also provided is a method of treating or preventing Staphylococcus aureus infections. The method includes administering an immunogenic amount of a vaccine an isolated Als protein family member having cell adhesion activity, or an immunogenic fragment thereof, in a pharmaceutically acceptable medium.
FILED Wednesday, February 03, 2016
APPL NO 15/014440
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0002 (20130101) Original (OR) Class
A61K 39/085 (20130101)
A61K 2039/58 (20130101)
A61K 2039/5156 (20130101)

Peptides
C07K 16/14 (20130101)
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300124 Milich et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) VLP Biotech, Inc. (San Diego, California)
ASSIGNEE(S) VLP BIOTECH, INC. (San Diego, California)
INVENTOR(S) David R. Milich (Escondido, California);  David C. Whitacre (San Diego, California)
ABSTRACT The present disclosure generally relates to hepadnavirus core antigens in which one or more endogenous b cell epitopes have been effectively removed. More specifically, the present disclosure relates to rodent hepadnavirus cores modified to diminish the antibody response to the core so as to enhance the antibody response to heterologous polypeptides included therein.
FILED Friday, March 14, 2014
APPL NO 14/774108
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/07 (20130101)
A61K 39/12 (20130101) Original (OR) Class
A61K 39/015 (20130101)
A61K 39/155 (20130101)
A61K 39/292 (20130101)
A61K 39/385 (20130101)
A61K 2039/5258 (20130101)
A61K 2039/55566 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2730/10023 (20130101)
C12N 2730/10034 (20130101)
C12N 2730/10043 (20130101)
C12N 2730/10134 (20130101)
C12N 2730/10143 (20130101)
C12N 2740/16034 (20130101)
C12N 2760/16134 (20130101)
C12N 2760/18534 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300127 Ravetch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Rockefeller University (New York, New York)
ASSIGNEE(S) The Rockefeller University (New York, New York)
INVENTOR(S) Jeffrey V. Ravetch (New York, New York);  Taia Wang (New York, New York);  Jad Mamaary (New York, New York)
ABSTRACT The present invention relates to immunogenic immune complexes, related compositions, and related methods. This invention addresses the above-described un-met need by providing an immune complex (IC) or immune complexes (ICs), which take advantages of Type II Fc receptor (FcR) interactions and signaling to elicit broader and more potent protective immune responses. In one aspect, the invention provides an immune complex comprising an antigenic agent and an isolated protein. The protein comprises an IgG Fc region and is capable of binding to a Type II Fc receptor. Preferably, the protein is an antibody or an Fc region-containing fragment thereof.
FILED Monday, March 21, 2016
APPL NO 15/560074
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101)
A61K 39/12 (20130101)
A61K 39/42 (20130101)
A61K 39/42 (20130101)
A61K 39/145 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 2039/505 (20130101)
A61K 2039/5252 (20130101)
A61K 2039/55516 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/16 (20180101)
A61P 35/00 (20180101)

Peptides
C07K 14/005 (20130101)
C07K 14/4748 (20130101)
C07K 16/1018 (20130101)
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)
C07K 2317/31 (20130101)
C07K 2317/41 (20130101)
C07K 2317/72 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2760/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300130 Shenk et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Thomas Shenk (Princeton, New Jersey);  Dai Wang (Blue Bell, Pennsylvania)
ABSTRACT Methods of increasing diversity in cytomegalovirus vaccines through the selection of cell type in which the virus is propagated, and the use of cytomegalovirus produced by those methods in the development of vaccine compositions, are disclosed. Vaccine compositions comprising CMV isolated from epithelial cells are also disclosed.
FILED Friday, July 29, 2016
APPL NO 15/223980
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/245 (20130101) Original (OR) Class
A61K 2039/54 (20130101)
A61K 2039/5252 (20130101)
A61K 2039/5254 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/16134 (20130101)
C12N 2710/16151 (20130101)
C12N 2710/16164 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300143 Sengupta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Shiladitya Sengupta (Waltham, Massachusetts);  Ashish Kulkarni (Waltham, Massachusetts);  Poornima Rao (Waltham, Massachusetts);  Bhaskar Roy (Belmont, Massachusetts)
ABSTRACT Described herein are compositions and methods relating to chemotherapeutic agent conjugates and the treatment of cancer.
FILED Monday, October 02, 2017
APPL NO 15/722831
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)
A61K 47/55 (20170801) Original (OR) Class
A61K 47/554 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300145 Irvine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Darrell J. Irvine (Arlington, Massachusetts);  Eric Dane (Cambridge, Massachusetts)
ABSTRACT The present disclosure provides a synthetic nanoparticle comprising a peptide nucleic acid (PNA) oligomer conjugated to a lipid, wherein the PNA oligomer noncovalently complexes with an immunomodulatory compound, thereby forming a nanoparticle. The nanoparticles are useful to elicit immune responses and can be used to treat a broad range of cancers and infectious diseases.
FILED Friday, July 14, 2017
APPL NO 15/650177
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5123 (20130101)
A61K 47/64 (20170801)
A61K 47/542 (20170801)
A61K 47/543 (20170801)
A61K 47/645 (20170801)
A61K 47/6425 (20170801) Original (OR) Class
A61K 47/6807 (20170801)
A61K 47/6911 (20170801)

Peptides
C07K 14/003 (20130101)
C07K 19/00 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 69/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300146 Gao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Guangping Gao (Westborough, Massachusetts);  Phillip D. Zamore (Northborough, Massachusetts)
ABSTRACT The invention in some aspects relates to isolated nucleic acids, compositions, and kits useful for identifying adeno-associated viruses in cells. In some aspects, the invention provides kits and methods for producing somatic transgenic animal models using recombinant AAV (rAAV) to an animal having at least one transgene that expresses a small interfering nucleic acid or at least one binding site for a miRNA.
FILED Friday, February 03, 2017
APPL NO 15/423720
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0275 (20130101)
A01K 2207/05 (20130101)
A01K 2217/058 (20130101)
A01K 2227/105 (20130101)
A01K 2267/03 (20130101)
A01K 2267/0331 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 38/00 (20130101)
A61K 48/0008 (20130101) Original (OR) Class
A61K 48/0058 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 15/8509 (20130101)
C12N 2015/8527 (20130101)
C12N 2310/13 (20130101)
C12N 2310/141 (20130101)
C12N 2320/32 (20130101)
C12N 2330/51 (20130101)
C12N 2710/10342 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14145 (20130101)
C12N 2820/002 (20130101)
C12N 2840/007 (20130101)
C12N 2840/102 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300151 Zheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
U.S. State Government
State of Texas
Cancer Prevention and Research Institute of Texas (TX-CPRIT)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Jie Zheng (Allen, Texas);  Mengxiao Yu (Plano, Texas)
ABSTRACT Methods and systems for evaluating renal function of a live subject. The method includes intravenously administering nanoparticles of a noble metal to the kidney of the live subject, followed by illuminating the kidney with a near infrared excitation wavelength such that the nanoparticles in the kidney fluoresce, and finally detecting presence or absence of nanoparticle fluorescence in the kidney. Detecting presence or absence of nanoparticle fluorescence includes obtaining at least one image of the kidney through the subject's skin.
FILED Monday, September 12, 2016
APPL NO 15/262307
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0071 (20130101)
A61B 5/4222 (20130101)
A61B 5/7275 (20130101)
A61B 2503/40 (20130101)
A61B 2503/42 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0004 (20130101)
A61K 49/0056 (20130101)
A61K 49/0065 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300269 Richter et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois);  RESONANCE MEDICAL, LLC (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois);  RESONANCE MEDICAL, LLC (Evanston, Illinois)
INVENTOR(S) Claus-Peter Richter (Skokie, Illinois);  Chris Heddon (Evanston, Illinois);  Petrina LaFaire (Chicago, Illinois);  Brian Dougherty (Mequon, Wisconsin)
ABSTRACT A system for neuromodulation device coding for stimulation of a patient includes a neural code library comprising digital representations of neural responses of neural units of at least one normal functioning animal, each digital representation corresponding to one of digital representations of stimulus; a sensory device configured to detect a sensory signal; an analyzer configured to identify one of the digital representations of stimulus in the neural code library in response to receipt of the sensory signal; a processing device configured, for each identified sensory signal, to retrieve the digital representations of neural responses of neural units corresponding to the identified sensory signal from the neural code library, and select one or more neural units of a patient to be stimulated by a neuromodulation device associated with the patient; and a transmitting device configured to stimulate the selected one or more neural units of the patient.
FILED Wednesday, August 22, 2018
APPL NO 16/109041
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0541 (20130101) Original (OR) Class
A61N 1/36036 (20170801)
A61N 1/36038 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300281 Joyner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Michael J. Joyner (Rochester, Minnesota);  Bruce D. Johnson (Rochester, Minnesota);  Thomas P. Olson (Cannon Falls, Minnesota)
ABSTRACT This document provides methods and materials for modulating afferent nerve signals to treat medical conditions such as CHF, CHF respiration, dyspnea, peripheral vascular disease (e.g., peripheral arterial disease or venous insufficiency), hypertension (e.g., age-associated hypertension, resistant hypertension, or chronic refractory hypertension), COPD, sleep apnea, and chronic forms of lung disease where muscle dysfunction is a part of the disease pathophysiology. For example, methods and materials involved in using electrical and/or chemical techniques to block or reduce afferent nerve signals (e.g., nerve signals of group III and/or IV afferents coming from skeletal muscle and/or the kidneys) are provided.
FILED Friday, March 08, 2013
APPL NO 14/383964
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/245 (20130101)
A61K 31/4468 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/3611 (20130101)
A61N 1/36057 (20130101)
A61N 1/36114 (20130101) Original (OR) Class
A61N 1/36117 (20130101)
A61N 1/36146 (20130101)
A61N 2/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301268 Evans et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Salk Institute for Biological Studies (La Jolla, California);  The University of Sydney (Sydney, Australia)
ASSIGNEE(S) The Salk Institute for Biological Studies (La Jolla, California);  University of Sydney (Sydney, Australia)
INVENTOR(S) Ronald M. Evans (La Jolla, California);  Michael Downes (San Diego, California);  Annette Atkins (San Diego, California);  Sungsoon Fang (La Jolla, California);  Jae Myoung Suh (San Diego, California);  Thomas J. Baiga (Escondido, California);  Ruth T. Yu (La Jolla, California);  John F. W. Keana (Eugene, Oregon);  Christopher Liddle (Tura Beach, Australia)
ABSTRACT Novel compounds having a formula
embodiments of a method of making the same, and of a composition comprising them are disclosed herein. Also disclosed are embodiments of a method of treating or preventing a metabolic disorder in a subject, comprising administering to a subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and treating or preventing a metabolic disorder in the subject. Additionally disclosed are embodiments of a method of treating or preventing inflammation in an intestinal region of a subject, comprising administering to the subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and thereby treating or preventing inflammation in the intestinal region of the subject.
FILED Monday, September 12, 2016
APPL NO 15/263033
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 59/001 (20130101)
C07B 59/002 (20130101)
C07B 2200/05 (20130101)

Acyclic or Carbocyclic Compounds
C07C 233/63 (20130101)
C07C 2601/14 (20170501)
C07C 2602/42 (20170501)

Heterocyclic Compounds
C07D 231/56 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301270 Sletten et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ellen May Sletten (Berkeley, California);  Carolyn Ruth Bertozzi (Stanford, California)
ABSTRACT The present disclosure features a strain-promoted [2+2+2] reaction that can be carried out under physiological conditions. In general, the reaction involves reacting a pi-electrophile with a low lying LUMO with a quadricyclane on a biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo and in vitro. The reaction is compatible with modification of living cells. In certain embodiments, the pi-electrophile can comprise a molecule of interest that is desired for delivery to a quadricyclane-containing biomolecule via [2+2+2] reaction.
FILED Wednesday, January 18, 2017
APPL NO 15/409354
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 49/04 (20130101)
C07C 49/76 (20130101)
C07C 69/013 (20130101)
C07C 69/76 (20130101)
C07C 69/96 (20130101)
C07C 245/04 (20130101)
C07C 255/46 (20130101)
C07C 271/42 (20130101)
C07C 323/16 (20130101)
C07C 323/56 (20130101)
C07C 323/64 (20130101)
C07C 2601/14 (20170501)

Heterocyclic Compounds
C07D 225/02 (20130101)
C07D 249/04 (20130101)
C07D 249/12 (20130101) Original (OR) Class
C07D 339/06 (20130101)
C07D 405/12 (20130101)
C07D 495/04 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 15/045 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0602 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301285 Miller et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Tennessee Research Foundation (Knoxville, Tennessee);  GTx, Inc. (Memphis, Tennessee)
ASSIGNEE(S) GTX, INC. (Memphis, Tennessee);  UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Noxville, Tennessee)
INVENTOR(S) Duane D. Miller (Collierville, Tennessee);  Jianjun Chen (Knoxville, Tennessee);  James T. Dalton (Ann Arbor, Michigan);  Chien-Ming Li (Fremont, California);  Sunjoo Ahn (Daejeon, South Korea);  Wei Li (Germantown, Tennessee)
ABSTRACT The present invention relates to a compound of formula XXII and a compound of formula 17ya, which are defined as anywhere in the specification, to a composition comprising the same, and to a method of using thereof in the treatment of various forms of cancer.
FILED Tuesday, April 21, 2015
APPL NO 14/692597
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4178 (20130101)
A61K 31/4178 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 233/02 (20130101)
C07D 233/22 (20130101)
C07D 233/54 (20130101)
C07D 263/06 (20130101)
C07D 263/14 (20130101)
C07D 263/32 (20130101)
C07D 277/04 (20130101)
C07D 277/24 (20130101)
C07D 277/28 (20130101)
C07D 277/56 (20130101)
C07D 401/04 (20130101)
C07D 401/06 (20130101)
C07D 403/04 (20130101) Original (OR) Class
C07D 413/04 (20130101)
C07D 413/06 (20130101)
C07D 417/04 (20130101)
C07D 417/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301294 Lewis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Mental Health (NIMH)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS GENERAL HOSPITAL (Boston, Massachusetts);  BRIGHAM AND WOMEN'S HOSPITAL (Boston, Massachusetts)
ASSIGNEE(S) THE BROAD INSTITUTE INC. (Cambridge, Massachusetts);  MASSACHUSETTS GENERAL HOSPITAL (Boston, Massachusetts);  BRIGHAM AND WOMEN'S HOSPITAL (Boston, Massachusetts)
INVENTOR(S) Timothy A. Lewis (Marlborough, Massachusetts);  Sivaraman Dandapani (Malden, Massachusetts);  Deborah Hung (Cambridge, Massachusetts);  Benito Munoz (Newtonville, Massachusetts);  Partha Nag (Somerville, Massachusetts);  Sarah Grant (Boston, Massachusetts);  Tomohiko Kawate (Cambridge, Massachusetts)
ABSTRACT Disclosed are compounds that can be used for treating tuberculosis.
FILED Wednesday, March 12, 2014
APPL NO 14/776477
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 263/46 (20130101)
C07D 271/10 (20130101)
C07D 271/113 (20130101)
C07D 285/125 (20130101)
C07D 413/04 (20130101)
C07D 413/12 (20130101) Original (OR) Class
C07D 413/14 (20130101)
C07D 417/04 (20130101)
C07D 417/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301314 Frankowski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia);  University of Kansas (Lawrence, Kansas);  Northwestern University (Evanston, Illinois)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia);  University of Kansas (Lawrence, Kansas);  Northwestern University (Evanston, Illinois)
INVENTOR(S) Kevin Frankowski (Lawrence, Kansas);  Samarjit Patnaik (Gaithersburg, Maryland);  Sui Huang (Evanston, Illinois);  Juan Jose Marugan (Gaithersburg, Maryland);  John Norton (San Diego, California);  Frank J. Schoenen (Lawrence, Kansas);  Noel Terrence Southall (Chevy Chase, Maryland);  Steven Titus (Elkridge, Maryland);  Wei Zheng (Potomac, Maryland);  Chen Wang (Chicago, Illinois)
ABSTRACT The disclosure provides compounds for reducing the prevalence of the perinucleolar compartment in cells, for example, of formula (I), wherein R1, R2, R3, and R4 are as defined herein, that are useful in treating a disease or disorder associated with increased prevalence of the perinucleolar compartment, such as cancer. Also disclosed is a composition containing a pharmaceutically acceptable carrier and at least one compound embodying the principles of the invention, and a method of treating or preventing cancer in a mammal.
FILED Friday, May 26, 2017
APPL NO 15/606740
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101)
A61K 31/695 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 487/04 (20130101) Original (OR) Class

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/1804 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301320 Markowitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio);  Board of Regents of the University of Texas System (Austin, Texas);  University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky);  Case Western Reserve University (Cleveland, Ohio);  Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Sanford Markowitz (Pepper Pike, Ohio);  James K. V. Willson (Dallas, Texas);  Bruce Posner (Richardson, Texas);  Joseph Ready (Carrolton, Texas);  Youngyou Zhang (Cleveland, Ohio);  Hsin-Hsiung Tai (Lexington, Kentucky);  Monika Antczak (Ft. Worth, Texas);  Stanton Gerson (Hunting Valley, Ohio);  KiBeom Bae (Buk-gu, South Korea);  Sung Yeun Yang (Yeonje-Gu, South Korea);  Amar Desai (Cleveland, Ohio)
ABSTRACT Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors and 15-PGDH activators described herein.
FILED Tuesday, November 22, 2016
APPL NO 15/359330
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101)
A61K 31/4365 (20130101)

Acyclic or Carbocyclic Compounds
C07C 311/21 (20130101)
C07C 2601/14 (20170501)

Heterocyclic Compounds
C07D 207/263 (20130101)
C07D 209/08 (20130101)
C07D 213/71 (20130101)
C07D 213/73 (20130101)
C07D 213/75 (20130101)
C07D 213/76 (20130101)
C07D 215/08 (20130101)
C07D 237/20 (20130101)
C07D 239/42 (20130101)
C07D 241/20 (20130101)
C07D 261/14 (20130101)
C07D 275/03 (20130101)
C07D 277/46 (20130101)
C07D 295/185 (20130101)
C07D 405/12 (20130101)
C07D 495/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301349 Cook et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) BIOSEARCH TECHNOLOGIES, INC. (Petaluma, California)
ASSIGNEE(S) BIOSEARCH TECHNOLOGIES, INC. (Petaluma, California)
INVENTOR(S) Ronald M. Cook (Novato, California);  Matt Lyttle (San Rafael, California);  Daren Dick (San Rafael, California)
ABSTRACT The present invention provides a family of dark quenchers, termed Black Hole Quenchers (“BHQs”), that are efficient quenchers of excited state energy but which are themselves substantially non-fluorescent. Also provided are methods of using the BHQs, probes incorporating the BHQs and methods of using the probes.
FILED Monday, March 30, 2015
APPL NO 14/673118
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/11 (20130101)

Acyclic or Carbocyclic Compounds
C07C 245/08 (20130101)

Heterocyclic Compounds
C07D 241/46 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/091 (20130101)
C07F 9/2408 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101) Original (OR) Class

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 31/043 (20130101)
C09B 56/00 (20130101)
C09B 56/12 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6818 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/542 (20130101)
G01N 33/582 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301355 Abdel-Malek et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Cincinnati (Cincinnati, Ohio)
ASSIGNEE(S) University of Cincinnati (Cincinnati, Ohio)
INVENTOR(S) Zalfa A. Abdel-Malek (Cincinnati, Ohio);  Leonid Koikov (Cincinnati, Ohio);  James J. Knittel (Belchertown, Massachusetts)
ABSTRACT Short tri- and tetrapeptides according to the following Formula I Ar(CH2)mX1—X2—CO—X3—X4—X5-(Trp)n-NX6R are potent, selective agonists of melanocortin 1 receptor (MC1R). Provided herein are pharmaceutical compositions including Formula I peptide agonists of MC1R and methods of treating skin diseases and disorders that include administering to an individual in need thereof a therapeutic amount of a Formula I peptide. The peptides, pharmaceutical compositions, and methods described herein are useful in the treatment of diseases and disorders that benefit from agonism of MC1R, including melanoma, basal cell carcinoma, squamous cell carcinoma, porphyria, polymorphous light eruption, vitiligo, and solar urticaria.
FILED Thursday, October 26, 2017
APPL NO 15/794301
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 8/06 (20130101)
A61K 8/64 (20130101)
A61K 9/0014 (20130101)
A61K 38/00 (20130101)
A61K 38/06 (20130101)
A61K 38/07 (20130101)

Specific Use of Cosmetics or Similar Toilet Preparations
A61Q 17/04 (20130101)
A61Q 19/004 (20130101)
A61Q 19/04 (20130101)
A61Q 19/08 (20130101)

Peptides
C07K 5/0821 (20130101)
C07K 5/1024 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301358 Looby et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Collagen Medical, LLC (Boston, Massachusetts)
ASSIGNEE(S) Collagen Medical, LLC (Boston, Massachusetts)
INVENTOR(S) Richard J. Looby (Reading, Massachusetts);  Peter D. Caravan (Cambridge, Massachusetts);  Thomas J. McMurry (Winchester, Massachusetts)
ABSTRACT Compounds and methods for imaging and/or assessing collagen are described. The compounds can include collagen binding peptides.
FILED Wednesday, June 29, 2016
APPL NO 15/196626
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/14 (20130101)
A61K 49/085 (20130101)

Peptides
C07K 7/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301360 Deverman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Mental Health (NIMH)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Benjamin E. Deverman (Pasadena, California);  Paul H. Patterson (Altadena, California);  Viviana Gradinaru (La Canada-Flintridge, California)
ABSTRACT Provided herein are methods of selective screening. In addition, various targeting proteins and sequences, as well as methods of their use, are also provided.
FILED Wednesday, February 01, 2017
APPL NO 15/422259
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/47 (20130101)
A61K 38/50 (20130101)
A61K 38/1709 (20130101)
A61K 38/2093 (20130101)
A61K 38/4813 (20130101)
A61K 39/3955 (20130101)
A61K 48/005 (20130101)
A61K 48/0058 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 14/005 (20130101) Original (OR) Class
C07K 2319/33 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 15/1068 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14145 (20130101)
C12N 2810/6027 (20130101)

Enzymes
C12Y 304/14009 (20130101)
C12Y 305/01015 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301366 Drivas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Theodore G. Drivas (Philadelphia, Pennsylvania);  Jean Bennett (Bryn Mawr, Pennsylvania)
ABSTRACT Compositions are provided that comprise a recombinant vector carrying a nucleic acid sequence encoding a fragment of CEP290 lacking all or part of its N-terminal and C-terminal inhibitory regions, under the control of regulatory sequences which express the product of said gene in a selected cell of a mammalian subject, and a pharmaceutically acceptable carrier. These and other compositions are disclosed with are useful in methods for treating a mammalian subject having a disease associated with a CEP290 mutation, such as Lebers Congenital Amaurosis.
FILED Monday, November 05, 2018
APPL NO 16/180892
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 48/00 (20130101)

Peptides
C07K 14/47 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301370 Payne et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Aimee S. Payne (Merion Station, Pennsylvania);  Christoph T. Ellebrecht (Philadelphia, Pennsylvania);  Vijay Bhoj (Philadelphia, Pennsylvania);  Michael C. Milone (Cherry Hill, New Jersey)
ABSTRACT The invention includes compositions comprising at least one chimeric autoantibody receptor (CAAR) specific for an autoantibody, vectors comprising the same, compositions comprising CAAR vectors packaged in viral particles, and recombinant T cells comprising the CAAR. The invention also includes methods of making a genetically modified T cell expressing a CAAR (CAART) wherein the expressed CAAR comprises a desmoglein extracellular domain.
FILED Friday, May 01, 2015
APPL NO 15/307644
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0008 (20130101)
A61K 48/00 (20130101)
A61K 2039/57 (20130101)
A61K 2039/5158 (20130101)

Peptides
C07K 14/705 (20130101) Original (OR) Class
C07K 16/28 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301377 Graham et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Barney Graham (Rockville, Maryland);  Wing-Pui Kong (Germantown, Maryland);  Kayvon Modjarrad (Bethesda, Maryland);  Lingshu Wang (North Potomac, Maryland);  Wei Shi (Rockville, Maryland);  Michael Gordon Joyce (Washington, District of Columbia);  Masaru Kanekiyo (Chevy Chase, Maryland);  John Mascola (Rockville, Maryland)
ABSTRACT Methods of inducing an immune response in a subject to the Middle East respiratory syndrome coronavirus (MERS-CoV) are provided. In several embodiments, the immune response is a protective immune response that inhibits or prevents MERS-CoV infection in the subject. Recombinant MERS-CoV polypeptides and nucleic acid molecules encoding same are also provided. Additionally, neutralizing antibodies that specifically bind to MERS-CoV S protein and antigen binding fragments thereof are disclosed. The antibodies and antigen binding fragments are useful, for example, in methods of detecting MERS-CoV S protein in a sample or in a subject, as well as methods of preventing and treating a MERS-CoV infection in a subject.
FILED Wednesday, February 24, 2016
APPL NO 15/553466
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/215 (20130101)
A61K 2039/53 (20130101)
A61K 2039/57 (20130101)
A61K 2039/545 (20130101)
A61K 2039/55505 (20130101)
A61K 2039/55566 (20130101)
A61K 2039/55572 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 14/165 (20130101)
C07K 16/10 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)
C07K 2317/33 (20130101)
C07K 2317/34 (20130101)
C07K 2317/52 (20130101)
C07K 2317/54 (20130101)
C07K 2317/55 (20130101)
C07K 2317/56 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
C07K 2317/567 (20130101)
C07K 2317/622 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2770/20034 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101)
G01N 2333/165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301590 Kam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Lance C. Kam (New York, New York);  Helen H. Lu (New York, New York);  Sarah E. De Leo (Baton Rouge, Louisiana);  Keenan T. Bashour (Hillsborough, California);  Danielle Bogdanowicz (Cortlandt Manor, New York);  Philip Chuang (New York, New York)
ABSTRACT The disclosure provides for compositions, systems, and methods of cell expansion, stimulation and/or differentiation. The disclosure further provides for a mesh substrate and associated methods capable of stimulating cell expansion, for example, T cell or stem cell expansion. In another aspect, the disclosure provides for an electrospun mesh substrate and methods of using thereof comprising a silicone rubber composition, for example, polydimethylsiloxane, PLC, or combinations thereof.
FILED Friday, April 10, 2015
APPL NO 15/302475
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 5/0075 (20130101) Original (OR) Class
C12N 5/0636 (20130101)
C12N 5/0662 (20130101)
C12N 2531/00 (20130101)
C12N 2533/30 (20130101)
C12N 2533/40 (20130101)
C12N 2533/50 (20130101)

Knitting
D04B 21/12 (20130101)

Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials
D06M 15/15 (20130101)
D06M 2101/30 (20130101)
D06M 2101/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301605 Wickens et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Marvin P. Wickens (Madison, Wisconsin);  Melanie A. Preston (Madison, Wisconsin)
ABSTRACT Methods, kits, and compositions of matter relating to poly(UG) polymerases are disclosed. In one embodiment, a method includes: contacting an RNA substrate with a poly(UG) polymerase; and allowing the poly(UG) polymerase to add a poly(UG) sequence to the end of the RNA substrate by retaining contact between the RNA substrate and the poly(UG) polymerase for a period of time from about 1 second to about 28 days. The poly(UG) polymerase can be Caenorhabditis elegans RDE-3.
FILED Tuesday, November 17, 2015
APPL NO 14/943229
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1247 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6846 (20130101)
C12Q 1/6846 (20130101)
C12Q 2521/119 (20130101)

Enzymes
C12Y 207/07 (20130101)
C12Y 207/07006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301608 Raushel et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) The Texas A and M University System (College Station, Texas)
INVENTOR(S) Frank M. Raushel (College Station, Texas);  Andrew N. Bigley (North Zulch, Texas)
ABSTRACT Variants of phosphotriesterase have been created that exhibit enhanced hydrolysis of V-type and G-type nerve agents over wild-type phosphotriesterase. V- and G-type nerve agents have an SP and RP enantiomer. The SP enantiomers are more toxic. V-type nerve agents are among the most toxic substances known. Variants of phosphotriesterase can prefer to hydrolyze one enantiomer of VX over the other enantiomer.
FILED Friday, June 19, 2015
APPL NO 15/320490
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus
A62D 3/02 (20130101)
A62D 2101/02 (20130101)
A62D 2101/26 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101) Original (OR) Class

Enzymes
C12Y 301/03008 (20130101)
C12Y 301/08001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301613 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Xiao Wang (Chandler, Arizona);  Kylie Standage-Beier (Phoenix, Arizona)
ABSTRACT The present invention relates to kits and methods of modifying the prokaryotic genome a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas system that utilized one nicking Cas nuclease and crRNAs. The kid and methods delete or replace portions of the prokaryotic genome. In some embodiments, an entire gene or multiple genes may be deleted or replaced.
FILED Friday, September 09, 2016
APPL NO 15/260788
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/01 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301621 Shapiro et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Bruce A. Shapiro (Gaithersburg, Maryland);  Kirill A. Afonin (Charlotte, North Carolina);  Mathias D. Viard (Frederick, Maryland);  Angelica N. Martins (Frederick, Maryland)
ABSTRACT The instant invention provides RNA nanoparticles and R/DNA chimeric nanoparticles comprising one or more functionalities. The multifunctional RNA nanoparticles are suitable for therapeutic or diagnostic use in a number of diseases or disorders.
FILED Wednesday, September 17, 2014
APPL NO 15/022530
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 47/549 (20170801)
A61K 47/6929 (20170801)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/87 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 15/1132 (20130101)
C12N 2310/14 (20130101)
C12N 2310/51 (20130101)
C12N 2310/52 (20130101)
C12N 2310/351 (20130101)
C12N 2310/3519 (20130101)
C12N 2320/32 (20130101)
C12N 2330/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301622 Mirkin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  William E. Briley (Chicago, Illinois);  Pratik S. Randeria (Hoffman Estates, Illinois);  Nathaniel J. Kim (Carmel, Indiana)
ABSTRACT The present invention relates to methods of detecting and tracking a target molecule using a nanoparticle wherein the nanoparticle comprises a polynucleotide that can specifically associate with the target molecule, and wherein the association results in a change in a detectable marker that can be measured after association with the target molecule.
FILED Tuesday, November 04, 2014
APPL NO 15/034005
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/3517 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6823 (20130101)
C12Q 1/6823 (20130101)
C12Q 2563/155 (20130101)
C12Q 2563/179 (20130101)
C12Q 2565/519 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301624 Ting et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts);  Aalborg University (Aalborg, Denmark)
INVENTOR(S) David T. Ting (Dover, Massachusetts);  Daniel A. Haber (Chestnut Hill, Massachusetts);  Shyamala Maheswaran (Lexington, Massachusetts);  Francesca Bersani (Turin, Italy);  Anders M. Naar (Arlington, Massachusetts);  Mihir Shivadatta Rajurkar (Worcester, Massachusetts);  Sakari Kauppinen (Holte, Denmark);  Andreas Petri (Frederiksberg, Denmark)
ABSTRACT Methods for treating cancer, e.g., cancer of epithelial origin, by specifically targeting human satellite II (HSATII) using sequence specific agents such as oligonucleotides. As shown herein, the hetero chromatic HSATII satellite repeat is silenced in normal cells, but massively over expressed in epithelial cancers and in cancer cell lines when grown as xenografts or in 3D culture. Induction of HSATII RNA, either in xenografts or using in vitro reconstitution models, suggests the appearance of complementary DNA intermediates.
FILED Thursday, June 25, 2015
APPL NO 15/321391
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/315 (20130101)
C12N 2310/321 (20130101)
C12N 2310/341 (20130101)
C12N 2310/3231 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301626 O'Rourke et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Sara Marie O'Rourke (Santa Cruz, California);  William Gregory Scott (Santa Cruz, California)
ABSTRACT Provided are minimal hammerhead ribozymes and catalytic strands thereof. Aspects of the present disclosure include a catalytic strand of a minimal hammerhead ribozyme, the catalytic strand including a catalytic core region, a stem I-forming region, a stem II region, and a stem III-forming region. The catalytic strand hybridizes to a target strand via the stem I-forming region and the stem III-forming region. A nucleotide (e.g., an adenine, cytosine, or a natural or non-natural nucleotide base having hydrogen bond donor and acceptor functionalities at positions analogous to those of adenine or cytosine) present in a stem II loop base pairs with a nucleotide (e.g., uracil or cytosine) at position 1.7 of the target strand. Also provided are compositions that include the catalytic strands, and methods of using the catalytic strands, e.g., in a variety of different applications, as well as kits that find use in practicing embodiments of the methods.
FILED Tuesday, March 01, 2016
APPL NO 15/554660
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/70 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101)
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 15/1132 (20130101)
C12N 2310/121 (20130101)
C12N 2320/13 (20130101)
C12N 2320/50 (20130101)
C12N 2320/51 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301648 Vandenberghe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Luk Vandenberghe (Weston, Massachusetts);  Guangping Gao (Westborough, Massachusetts);  James M. Wilson (Glen Mills, Pennsylvania)
ABSTRACT A method of correcting singletons in a selected AAV sequence in order to increasing the packaging yield, transduction efficiency, and/or gene transfer efficiency of the selected AAV is provided. This method involves altering one or more singletons in the parental AAV capsid to conform the singleton to the amino acid in the corresponding position(s) of the aligned functional AAV capsid sequences.
FILED Wednesday, February 18, 2015
APPL NO 14/624671
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)
A61K 48/005 (20130101)
A61K 48/0091 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2750/14122 (20130101)
C12N 2750/14142 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14152 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301650 Gao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Guangping Gao (Westborough, Massachusetts);  James M. Wilson (Philadelphia, Pennsylvania);  Mauricio R. Alvira (Philadelphia, Pennsylvania)
ABSTRACT Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles.
FILED Monday, May 01, 2017
APPL NO 15/582815
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 35/761 (20130101)
A61K 38/45 (20130101)
A61K 38/177 (20130101)
A61K 38/4846 (20130101)
A61K 48/00 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 14/705 (20130101)
C07K 14/755 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/644 (20130101)
C12N 9/1018 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 15/8645 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14152 (20130101)
C12N 2830/008 (20130101)
C12N 2830/48 (20130101)
C12N 2830/85 (20130101)

Enzymes
C12Y 201/03003 (20130101)
C12Y 304/21021 (20130101)
C12Y 304/21022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301651 Doudna et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California);  University of Vienna (Vienna, Austria);  Emmanuelle Charpentier (Braunschweig, Germany)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  University of Vienna (Vienna, Austria);  Emmanuelle Charpentier (Braunschweig, Germany)
INVENTOR(S) Jennifer A. Doudna (Berkeley, California);  Martin Jinek (Berkeley, California);  Emmanuelle Charpentier (Braunschweig, Germany);  Krzysztof Chylinski (Vienna, Austria)
ABSTRACT The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.
FILED Monday, April 13, 2015
APPL NO 14/685504
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 6/4684 (20180501)

Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/027 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/465 (20130101)
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/63 (20130101)
C12N 15/70 (20130101)
C12N 15/90 (20130101)
C12N 15/102 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 15/746 (20130101)
C12N 15/902 (20130101)
C12N 15/907 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/13 (20130101)
C12N 2310/14 (20130101)
C12N 2310/20 (20170501)
C12N 2310/31 (20130101)
C12N 2310/32 (20130101)
C12N 2310/33 (20130101)
C12N 2310/531 (20130101)
C12N 2310/3519 (20130101)
C12N 2800/80 (20130101)

Enzymes
C12Y 301/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301664 Seleem
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Mohamed Seleem (West Lafayette, Indiana)
ABSTRACT Disclosed herewith is drug repurposing efforts that lead to the discovery of prior non-antibiotic drugs can be used in clinical applicable ranges to treat patients of bacterial infection. These repurposed drug can be used either alone or in combination with traditional antibiotic drugs to treat bacterial strains that may develop or already have developed drug resistance.
FILED Thursday, December 15, 2016
APPL NO 15/380648
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/41 (20130101)
A61K 31/351 (20130101)
A61K 31/439 (20130101)
A61K 31/496 (20130101)
A61K 31/575 (20130101)
A61K 31/5377 (20130101)
A61K 31/7036 (20130101)
A61K 31/7048 (20130101)
A61K 31/7056 (20130101)
A61K 31/7072 (20130101)
A61K 31/7135 (20130101)
A61K 38/14 (20130101)
A61K 38/15 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302528 Ilev et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Ilko Kolev Ilev (Rockville, Maryland);  Bennett Neave Walker (Silver Spring, Maryland);  Robert Harold James (Gaithersburg, Maryland);  Don Calogero (Montgomery Village, Maryland)
ABSTRACT Described are systems, devices, and methods related to a confocal laser method (CLM) for accurately measuring dioptric powers and other critical optical properties of intraocular lenses (IOLs), such as toric IOLs. Described test results demonstrate that the described CLM systems and methods can be used to measure the spherical equivalent and cylinder powers of toric IOLs with high accuracy. Furthermore, some described systems include a rotating rectangular slit aperture that can be used for precise differentiation of the two focal planes and isolation of the two focal points, and thus, for accurate measurement of the anterior cylinder axis of toric IOLs.
FILED Wednesday, January 27, 2016
APPL NO 15/545018
ART UNIT 2886 — Optics
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/1645 (20150401)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 11/0207 (20130101)
G01M 11/0228 (20130101)
G01M 11/0235 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302536 Shi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) DIAGNOLOGIX, LLC (San Diego, California)
ASSIGNEE(S) DIAGNOLOGIX, LLC (San Diego, California)
INVENTOR(S) Guixin Shi (San Diego, California);  Michael Benchimol (San Diego, California);  Tyler Watson (San Diego, California)
ABSTRACT Systems and devices for the isolation of biological agents that are infused in a solution causing those agents to float. These systems and devices have numerous research, diagnostic, clinical, consumer, and other applications. An aspect of the disclosure provides for an apparatus for isolation or enrichment of biological agents from a sample comprising: a sample container comprising an inner volume to hold a sample and a plurality of micro bubbles, a tapered end and an open end, a plunger inserted into the open end and a tip of the tapered end forming an acute angle relative to the horizontal axis of the sample container, wherein the plurality of micro bubbles float one or more biological agents of the sample and wherein the plunger moves towards the tip to isolate or enrich the one or more biological agents from the sample.
FILED Friday, May 08, 2015
APPL NO 15/309413
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Flotation; Differential Sedimentation
B03D 1/14 (20130101)
B03D 2203/003 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 47/04 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/4077 (20130101) Original (OR) Class
G01N 33/536 (20130101)
G01N 2001/4066 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302629 Carrier
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) France Carrier (Highland, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
INVENTOR(S) France Carrier (Highland, Maryland)
ABSTRACT The present invention is drawn to therapeutics which can target hnRNP A18, a regulator of protein translation in cancer cells. The invention provides a method of treating cancer in a subject comprising administering to the subject a therapeutically effective amount of a composition that decreases the level and/or activity of heterogenous ribonucleoprotein A18 (hnRNP A18). The composition can comprise a nucleic acid molecule that binds to at least a portion of a nucleotide sequence coding for hnRNP A18. The invention also provides a composition for treating cancer comprising a nucleic acid or antibody that is capable of decreasing the level and/or activity of hnRNP A18 and a pharmaceutically acceptable carrier. The invention also provides methods of screening for an anti-cancer compound.
FILED Tuesday, March 29, 2016
APPL NO 15/084459
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 16/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/14 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5011 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302644 Hideshima et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Teru Hideshima (Brookline, Massachusetts);  Kenneth C. Anderson (Wellesley, Massachusetts);  Francesca Cottini (Boston, Massachusetts)
ABSTRACT The invention provides, inter alia, methods of prognosing the survival of a multiple myeloma patient based levels of TP53RK in multiple myeloma cells of the patient. Also provided are methods of screening for therapeutic agents for treating multiple myeloma based on their ability to decrease TP53RK levels or activity in a patient with multiple myeloma.
FILED Tuesday, October 20, 2015
APPL NO 15/524186
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/485 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101)
G01N 33/57426 (20130101) Original (OR) Class
G01N 2333/912 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302650 Ng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Yao Zong Ng (Singapore, Singapore);  Pedro Alexis Baldera Aguayo (New York, New York);  Virginia W. Cornish (New York, New York);  Ehud Herbst (New York, New York)
ABSTRACT The present disclosure provides a high-throughput fluorescence polarization microorganism screening assay for a metabolite produced by a microorganism. The metabolite is detected using competition with a fluorescent reporter for a receptor that binds both the metabolite and the reporter. The present disclosure further provides materials used in such an assay, a kit for such an assay, an isolated microorganism identified using such an assay, and culture conditions identified using such an assay.
FILED Thursday, June 14, 2018
APPL NO 16/008777
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/10 (20130101)
C12N 15/1086 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/64 (20130101)
G01N 33/542 (20130101)
G01N 33/569 (20130101)
G01N 33/582 (20130101) Original (OR) Class
G01N 33/56944 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302658 Laurie
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Gordon W. Laurie (Charlottesville, Virginia)
ABSTRACT The present invention provides compositions and methods for identifying subjects suffering from dry eye that can be treated by topical administration of a composition comprising lacritin or a bioactive fragment thereof. The application discloses in part that a ˜90 KDa deglycanated form of syndecan-1 is abundant in tears of normal individuals but not individuals suffering from dry eye, whereas a ˜25 kDa syndecan-1 fragment is detectable in dry, but no normal tears.
FILED Wednesday, March 11, 2015
APPL NO 15/125357
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 38/18 (20130101)
A61K 38/1709 (20130101)

Peptides
C07K 14/475 (20130101)

Enzymes
C12Y 302/01166 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/68 (20130101)
G01N 33/573 (20130101)
G01N 33/6893 (20130101) Original (OR) Class
G01N 2333/924 (20130101)
G01N 2333/4706 (20130101)
G01N 2333/4722 (20130101)
G01N 2333/4728 (20130101)
G01N 2333/70596 (20130101)
G01N 2800/16 (20130101)
G01N 2800/162 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302722 Alsop et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) David Alsop (Newton, Massachusetts);  Gopal Varma (Boston, Massachusetts)
ASSIGNEE(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) David Alsop (Newton, Massachusetts);  Gopal Varma (Boston, Massachusetts)
ABSTRACT A system and method for producing a report about a subject from data collected from the subject using a magnetic resonance imaging (MRI] system. The method includes directing the MRI system to perform a pulse sequence to manipulate exchangeable magnetization in the subject and acquiring, with the MRI system, imaging data from the subject in response to the pulse sequence. The method also includes analyzing the effects of the frequencies of applied RF energy on the imaging data to identify inhomogeneous lines formed by a summation of multiple sublines centered at multiple different frequencies. The method further includes generating a report pertaining to inhomogeneous magnetization transfer occurring in the subject in response to the pulse sequence.
FILED Thursday, March 13, 2014
APPL NO 14/776872
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/4041 (20130101)
A61B 5/7278 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/50 (20130101)
G01R 33/4828 (20130101)
G01R 33/5605 (20130101) Original (OR) Class
G01R 33/5659 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302727 Rathi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Mental Health (NIMH)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Yogesh Rathi (Lexington, Massachusetts);  Lipeng Ning (Lexington, Massachusetts);  Oleg Michailovich (Ontario, Canada);  Kawin Setsompop (Cambridge, Massachusetts)
ABSTRACT A system and method for producing high resolution diffusion information and imaging from a subject. In some aspects, the method includes receiving a plurality of low resolution diffusion images, each acquired with a different set of gradient directions and shifted in a slice direction, and generating a model correlating diffusion signals associated with the plurality of low resolution diffusion images and a high resolution diffusion image. The method also includes reconstructing the high resolution diffusion image by minimizing a cost function determined using the model. In some applications, the method further includes processing the high resolution diffusion image to generate a report providing diffusion information associated with the subject.
FILED Friday, November 13, 2015
APPL NO 14/940202
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5608 (20130101)
G01R 33/56341 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302731 Trzasko et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota)
ASSIGNEE(S) MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota)
INVENTOR(S) Joshua D. Trzasko (Rochester, Minnesota);  Matthew A. Bernstein (Rochester, Minnesota);  Shengzhen Tao (Rochester, Minnesota)
ABSTRACT A system and method for simultaneously reconstructing magnetic resonance images and correcting those imaged for gradient nonlinearity effects are provided. As opposed to conventional methods for gradient nonlinearity correction where distortion is corrected after image reconstruction is performed, the model-based method described here prospectively accounts for the effects of gradient nonlinearity during reconstruction. It is a discovery of the inventors that the method described here can reduce the blurring effect and resolution loss caused by conventional correction algorithms while achieving the same level of geometric correction.
FILED Friday, April 24, 2015
APPL NO 15/305443
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/58 (20130101)
G01R 33/482 (20130101)
G01R 33/4824 (20130101)
G01R 33/56572 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302924 Prakash et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Fogarty International Center (FIC)
National Center for Research Resources (NCRR)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Manu Prakash (San Francisco, California);  James Stanley Cybulski (Palo Alto, California);  James C. Clements (Everett, Washington)
ABSTRACT An optical device, such as a microscope, is disclosed that can be assembled from flat materials. The optical device can be assembled via a series of folds of a flat material. The optical microscope can include a stage for supporting a sample, an optic stage, and a light source. The optic stage can include one or more lenses. The optical microscope can be capable of obtaining simultaneous images from different forms of microscopy. The optical microscope may have bright field and filter field viewing capabilities wherein a user shifts from bright field to filter field by lateral movement of the stage containing a lens and a light source that cooperate to provide either the bright field or the filter field.
FILED Friday, June 30, 2017
APPL NO 15/639856
ART UNIT 2872 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/01 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/06 (20130101)
G02B 21/0008 (20130101)
G02B 21/26 (20130101)
G02B 21/0076 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304183 Mikhno et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York);  The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York);  The Research Foundation for the State University of New York (Albany, New York)
INVENTOR(S) Arthur Mikhno (Staten Island, New York);  Elsa D. Angelini (New York, New York);  Andrew F. Laine (New York, New York);  Todd Ogden (Teaneck, New Jersey);  Ramin Parsey (Mountain Lakes, New Jersey);  Joseph John Mann (Riverdale, New York)
ABSTRACT The present disclosure is directed to iterative regularized reconstruction methods. In certain embodiments, the methods incorporate locally-weighted total variation denoising to suppress artifacts induced by PSF modeling. In certain embodiments, the methods are useful for suppressing ringing artifacts while contrast recovery is maintained. In certain embodiments, the weighting scheme can be extended to noisy measures introducing a noise-independent weighting scheme. The present disclosure is also directed to a method for quantifying radioligand binding in a subject without collecting arterial blood. In certain embodiments, the methods incorporate using imaging data and electronic health records to predict one or more anchors, which are used to generate an aterial input function (AIF) for the radioligand.
FILED Friday, September 02, 2016
APPL NO 15/256435
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/037 (20130101)
A61B 6/481 (20130101)
A61B 6/501 (20130101)
A61B 6/5205 (20130101)
A61B 6/5258 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 11/003 (20130101)
G06T 11/006 (20130101)
G06T 15/08 (20130101)
G06T 2207/10104 (20130101)
G06T 2207/10108 (20130101)
G06T 2207/30016 (20130101)
G06T 2211/424 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304311 Clark et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) BARRON ASSOCIATES, INC. (Charlottesville, Virginia)
ASSIGNEE(S) BARRON ASSOCIATES, INC. (Charlottesville, Virginia)
INVENTOR(S) Brian R. Clark (Charlottesville, Virginia);  Christopher J. Wiles (Charlottesville, Virginia)
ABSTRACT A communicator for autonomous monitoring, detecting, and tracking of movement and orientation of a portion of a body of a wearer is disclosed. The communicator includes a sensor configured to detect a translational and/or rotational movement of the portion of the body of the wearer; an altimeter to measure changes in altitude of the portion of the body of the wearer; and a processor configured to determine an orientation and/or position of the portion of the body of the wearer. The processor further configured to compensate for the measured changes in altitude. The sensor is implemented at least by one of the following: accelerometer(s), gyroscope(s), and/or magnetometer(s).
FILED Tuesday, December 05, 2017
APPL NO 15/832032
ART UNIT 2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 5/00 (20130101)
G01C 21/20 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 15/14 (20130101)
G01P 15/18 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/0206 (20130101)
G01R 33/0286 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 21/0446 (20130101) Original (OR) Class
G08B 25/08 (20130101)
G08B 25/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305692 Peterson
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Medtronic, Inc. (Minneapolis, Minnesota)
ASSIGNEE(S) Medtronic, Inc. (Minneapolis, Minnesota)
INVENTOR(S) Erik J. Peterson (Fridley, Minnesota)
ABSTRACT In one example, a method includes transitioning, responsive to determining that a charging coil of wireless charger is in proximity of an implantable medical device (IMD) and by the IMD, from operating in a non-pairing mode into a pairing mode of a far-field wireless communication protocol. In this example, operating in the paring mode comprises: receiving, by the IMD and via a transceiver of the far-field wireless communication protocol, a public encryption key from another device that is different than the wireless charger; and determining, based on the public encryption key of the other device and a public encryption key of the IMD, a link encryption key for future communication between the IMD and the other device. In this example, the method further includes communicating, by the IMD and based on the link encryption key, with the other device via the far-field wireless communication protocol.
FILED Wednesday, February 22, 2017
APPL NO 15/439503
ART UNIT 2435 — Cryptography and Security
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 31/002 (20130101)
A61M 2205/3523 (20130101)
A61M 2205/8206 (20130101)
A61M 2205/8243 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/3605 (20130101)
A61N 1/3787 (20130101)
A61N 1/37223 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/14 (20130101)
H04L 9/30 (20130101)
H04L 9/3236 (20130101) Original (OR) Class
H04L 2209/80 (20130101)
H04L 2209/88 (20130101)

Wireless Communication Networks
H04W 4/80 (20180201)
H04W 76/10 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10306135 Velipasalar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Syracuse University (Syracuse, New York)
ASSIGNEE(S) Syracuse University (Syracuse, New York)
INVENTOR(S) Senem Velipasalar (Fayetteville, New York);  Mauricio Casares (Lincoln, Nebraska);  Akhan Almagambetov (Nunda, New York)
ABSTRACT There is set forth herein a system including a camera device. In one embodiment the system is operative to perform image processing for detection of an event involving a human subject. There is set forth herein in one embodiment, a camera equipped system employed for fall detection.
FILED Monday, February 13, 2017
APPL NO 15/431186
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0077 (20130101)
A61B 5/1117 (20130101)
A61B 5/7264 (20130101)

Electric Digital Data Processing
G06F 19/00 (20130101)

Pictorial Communication, e.g Television
H04N 1/00029 (20130101)
H04N 1/00042 (20130101)
H04N 5/2253 (20130101)
H04N 5/23206 (20130101)
H04N 5/23219 (20130101) Original (OR) Class
H04N 7/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE47404 Rossignol
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Romark Laboratories, L.C. (Tampa, Florida)
ASSIGNEE(S) ROMARK LABORATORIES, L.C. (Tampa, Florida)
INVENTOR(S) Jean-Francois Rossignol (St. Petersburg, Florida)
ABSTRACT The present disclosure relates to methods for treating viral hepatitis, compounds useful in the treatment of viral hepatitis, and pharmaceutical compositions comprising such compounds. In one embodiment, pharmaceutical compositions comprising nitazoxanide, tizoxanide, or derivatives and/or mixtures thereof are provided, as well as methods of treating hepatitis C using such compositions.
FILED Friday, July 07, 2017
APPL NO 15/644637
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/426 (20130101) Original (OR) Class
A61K 31/426 (20130101)
A61K 31/7068 (20130101)
A61K 38/21 (20130101)
A61K 38/21 (20130101)
A61K 38/212 (20130101)
A61K 38/212 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 10300410 Ji et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Princeton Plasma Physics Laboratory (PPPL)
Federally Funded Research and Development Center (FFRDC)
Operated by Princeton University (PRINCETON) at Princeton, NJ
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S) Hantao Ji (Plainsboro, New Jersey);  Adam Cohen (Princeton Junction, New Jersey);  Phil Efthimion (Bedminster, New Jersey);  Eric Edlund (Princeton, New Jersey);  Erik Gilson (Princeton, New Jersey)
ABSTRACT Provided is an advanced liquid centrifuge using differentially rotating cylinders moveable rings at the ends thereof, as well as methods for the separation of fluids, preferably liquids.
FILED Monday, March 02, 2015
APPL NO 14/635701
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 21/34 (20130101)
B01D 21/0087 (20130101)
B01D 21/262 (20130101) Original (OR) Class

Centrifuges
B04B 1/00 (20130101)
B04B 9/00 (20130101)
B04B 11/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300430 Nguyen et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Du T. Nguyen (Fremont, California);  Roger D. Aines (Livermore, California);  Sarah E. Baker (Dublin, California);  William L. Bourcier (Livermore, California);  Eric B. Duoss (Dublin, California);  James S. Oakdale (Castro Valley, California);  Megan M. Smith (Livermore, California);  William L. Smith (Oakland, California);  Joshuah K. Stolaroff (Oakland, California);  Congwang Ye (Livermore, California)
ABSTRACT A composite material for gas capture, notably CO2 capture and storage. The composite material includes a mixture of a solid or liquid reactive filler and a gas-permeable polymer such that the reactive filler forms micron-scale domains in the polymer matrix.
FILED Friday, March 24, 2017
APPL NO 15/468297
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Separation
B01D 53/1475 (20130101)
B01D 53/1493 (20130101) Original (OR) Class
B01D 2252/202 (20130101)
B01D 2252/20405 (20130101)
B01D 2252/20421 (20130101)
B01D 2252/20484 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/206 (20130101)
B01J 20/2805 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 10/06 (20130101)
Y02C 10/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300438 Nulwala et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Hunaid B. Nulwala (Pittsburgh, Pennsylvania);  David Luebke (Pittsburgh, Pennsylvania);  Xu Zhou (Pittsburgh, Pennsylvania)
ABSTRACT Provided herein are compositions, CO2-permeable/selective membranes and related methods of making and using the membranes. Ionically cross-linked poly(ether)-based membranes were prepared for applications relating to CO2. These films were studied for their thermal curing behavior using DSC. The resulting free-standing membranes have Tgs near −64° C., TdS up to 230° C., and Young's modulus up to 4.2 MPa. These membranes showed CO2 permeabilities of 84-110 Barrer and CO2/N2 selectivity of 20-40.
FILED Wednesday, October 28, 2015
APPL NO 15/520962
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/22 (20130101)
B01D 53/228 (20130101)
B01D 67/0006 (20130101)
B01D 69/02 (20130101)
B01D 69/12 (20130101)
B01D 69/125 (20130101)
B01D 71/52 (20130101)
B01D 71/62 (20130101)
B01D 71/76 (20130101) Original (OR) Class
B01D 2257/504 (20130101)
B01D 2258/0283 (20130101)
B01D 2323/30 (20130101)
B01D 2323/40 (20130101)
B01D 2325/20 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 41/13 (20170101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 73/08 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 10/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300464 Lin et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) EverNu Technology LLC (Warminster, Pennsylvania)
ASSIGNEE(S) EverNu Technology, LLC (Warwick, Pennsylvania)
INVENTOR(S) Manhua Lin (Maple Glen, Pennsylvania);  Wai-si Eng (Maple Glen, Pennsylvania)
ABSTRACT Disclosed is a method for producing, among others, alkenes and/or saturated or unsaturated oxygenates and, which include at least one of an aldehyde and an acid, comprising subjecting the corresponding C3 to C5 aliphatic alcohols that are derivable from biomass, to a vapor phase process over the catalytic system in the presence of a gas mixture of oxygen, air or nitrogen and/or other suitable diluting gas. The catalyst system comprises multi-catalytic zones, in each of which the composition of the co-feed and other reaction parameter can be independently controlled.
FILED Friday, December 06, 2013
APPL NO 14/649929
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/002 (20130101)
B01J 23/28 (20130101)
B01J 23/30 (20130101)
B01J 23/687 (20130101)
B01J 23/888 (20130101)
B01J 23/8885 (20130101) Original (OR) Class
B01J 35/023 (20130101)
B01J 37/08 (20130101)
B01J 37/0036 (20130101)
B01J 2523/00 (20130101)
B01J 2523/00 (20130101)
B01J 2523/53 (20130101)
B01J 2523/55 (20130101)
B01J 2523/68 (20130101)

Acyclic or Carbocyclic Compounds
C07C 1/24 (20130101)
C07C 1/24 (20130101)
C07C 1/24 (20130101)
C07C 11/06 (20130101)
C07C 11/09 (20130101)
C07C 45/38 (20130101)
C07C 45/38 (20130101)
C07C 47/02 (20130101)
C07C 51/235 (20130101)
C07C 51/235 (20130101)
C07C 57/04 (20130101)
C07C 67/40 (20130101)
C07C 2523/10 (20130101)
C07C 2523/18 (20130101)
C07C 2523/22 (20130101)
C07C 2523/28 (20130101)
C07C 2523/30 (20130101)
C07C 2523/745 (20130101)
C07C 2523/888 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/52 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300474 Li
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Zhenglong Li (Knoxville, Tennessee)
ABSTRACT A method for producing one or more hydrocarbon compounds from at least one of 2,3-butanediol, acetoin, and ethanol, the method comprising contacting said at least one of 2,3-butanediol, acetoin, and ethanol with a catalyst at a temperature of at least 100° C. and up to 500° C. to result in said 2,3-butanediol, acetoin, and/or ethanol being converted to said one or more hydrocarbon compounds, wherein said catalyst is either: (i) a catalyst comprising nanoparticles composed of (a) a first metal oxide selected from the group consisting of zirconium oxide, cerium oxide, titanium oxide, and lanthanum oxide, and (b) a main group metal oxide; or (ii) a catalyst comprising a zeolite loaded with at least one metal selected from the group consisting of copper, silver, nickel, palladium, platinum, rhodium, and ruthenium in an amount of 1-30 wt % by weight of the zeolite.
FILED Thursday, August 09, 2018
APPL NO 16/059512
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/04 (20130101)
B01J 21/08 (20130101)
B01J 21/063 (20130101)
B01J 21/066 (20130101)
B01J 23/10 (20130101)
B01J 29/44 (20130101)
B01J 29/46 (20130101)
B01J 29/7038 (20130101)
B01J 35/0006 (20130101) Original (OR) Class

Acyclic or Carbocyclic Compounds
C07C 11/08 (20130101)
C07C 11/167 (20130101)
C07C 15/46 (20130101)
C07C 31/10 (20130101)
C07C 49/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301043 Shoer et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Naval Nuclear Laboratory (NNL)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts)
ASSIGNEE(S) THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts)
INVENTOR(S) Joseph Shoer (Cambridge, Massachusetts);  Leena Singh (Lexington, Massachusetts);  Sungyung Lim (Acton, Massachusetts);  Timothy Henderson (Ashland, Massachusetts)
ABSTRACT A conical scanning method and system is provided for orienting a spacecraft with respect to a source. The system includes a spacecraft and an incidence angle sensor secured to the spacecraft to sense a signal from a source. The incidence angle sensor has a boresight that is canted with respect to the principal axis. A processor communicates with actuators on the spacecraft to adjust an attitude of the spacecraft based on information received from the incidence angle sensor and to thereby align a principal axis of the spacecraft with a direction from the spacecraft to the source. The method and system can also rely on information received from source presence sensors. The source may be the Sun, or a non-solar signal source.
FILED Wednesday, November 23, 2016
APPL NO 15/360545
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/36 (20130101)
B64G 1/363 (20130101) Original (OR) Class
B64G 2001/245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301340 Boyle et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Timothy J. Boyle (Albuquerque, New Mexico);  LaRico Juan Treadwell (Albuquerque, New Mexico)
ABSTRACT Nickel nanoparticles can be synthesized using a variety of precursors (e.g., nickel amides [Ni(NR2)2], alkyls [NR2], and alkoxides [Ni(OR)2]).
FILED Thursday, August 03, 2017
APPL NO 15/668208
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0018 (20130101)
B22F 9/24 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 15/045 (20130101) Original (OR) Class

Production and Refining of Metals; Pretreatment of Raw Materials
C22B 23/0461 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/81 (20130101)
Y10S 977/773 (20130101)
Y10S 977/896 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301653 Reed et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Jennifer L. Reed (Madison, Wisconsin);  Joonhoon Kim (Busan, South Korea)
ABSTRACT Microorganisms that co-consume glucose with non-glucose carbohydrates, such as xylose, and methods of using same. The microorganisms comprise modifications that reduce or ablate the activity of a phosphoenolpyruvate (PEP):carbohydrate phosphotransferase system (PTS) protein or modifications that reduce or ablate the activity of a phosphoglucose isomerase and a GntR. The PTS protein may be selected from an enzyme I (EI), an HPr, an FPr, and an enzyme IIGlc (EIIGlc). Additional modifications include reduction or ablation of the activity of a pyruvate formate lyase, a lactate dehydrogenase, and a fumarate reductase and inclusion of recombinant pyruvate decarboxylase and alcohol dehydrogenase genes. The microorganisms are particularly suited to co-consuming glucose and xylose in media containing these substrates and producing ethanol therefrom.
FILED Monday, July 06, 2015
APPL NO 14/791590
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/14 (20130101)
C12N 1/20 (20130101)
C12N 9/0006 (20130101)
C12N 9/88 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/06 (20130101)
C12P 7/065 (20130101) Original (OR) Class

Enzymes
C12Y 101/01001 (20130101)
C12Y 401/01001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301729 Willit et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) James L. Willit (Batavia, Illinois);  Mark A. Williamson (Naperville, Illinois);  Stanley G. Wiedmeyer (Glen Ellyn, Illinois);  Magdalena M. Tylka (Willow Springs, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) James L. Willit (Batavia, Illinois);  Mark A. Williamson (Naperville, Illinois);  Stanley G. Wiedmeyer (Glen Ellyn, Illinois);  Magdalena M. Tylka (Willow Springs, Illinois)
ABSTRACT The invention provides a system for collecting metal in an electrorefining process, the system having a hollow cathode; and a container defining an upwardly extending surface adapted to be received by the hollow cathode. An embodiment of the invention provides for metal reduction to occur on laterally facing and medially facing surfaces of the cathode such that electrolyte resides between surfaces of the cathode. Also provided is a metal electrorefining process having the steps of subjecting molten salt containing metal moieties to electrolysis wherein reduced metal accumulates in a cathode-cup construct in a first position; raising the construct to a second position above the molten salt while subjecting the construct to heat from the molten salt; withdrawing the cathode from the construct into a vestibule to the electrorefiner to a third position; and removing the cathode and cup from the electrorefiner to a fourth position.
FILED Friday, April 29, 2016
APPL NO 15/143173
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor
C25C 3/34 (20130101)
C25C 7/025 (20130101) Original (OR) Class

Nuclear Reactors
G21C 19/42 (20130101)
G21C 19/48 (20130101)

Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management
Y02W 30/884 (20150501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302252 Kuczek et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Andrzej Ernest Kuczek (Bristol, Connecticut);  Matthew E. Lynch (Canton, Connecticut);  Paul F. Croteau (Columbia, Connecticut);  Tahany Ibrahim El-Wardany (Bloomfield, Connecticut);  Ellen Y. Sun (South Windsor, Connecticut);  Wenping Zhao (Glastonbury, Connecticut);  Daniel V. Viens (Mansfield Center, Connecticut)
ABSTRACT An illustrative example container includes a plurality of internal support members having a surface contour that at least approximates a minimum surface. The plurality of internal support members collectively provide structural support for carrying loads on the container. The plurality of internal support members collectively establish a plurality of cavities for at least temporarily containing fluid. An outer shell is connected with at least some of the internal support members. The outer shell includes a plurality of curved surfaces. The outer shell encloses the cavities.
FILED Monday, April 14, 2014
APPL NO 15/302532
ART UNIT 3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases
F17C 1/08 (20130101) Original (OR) Class
F17C 1/14 (20130101)
F17C 2201/054 (20130101)
F17C 2201/056 (20130101)
F17C 2201/0147 (20130101)
F17C 2201/0157 (20130101)
F17C 2203/013 (20130101)
F17C 2203/0636 (20130101)
F17C 2209/221 (20130101)
F17C 2223/0123 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 3/12 (20130101)
F28F 3/086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302369 Siebert
FUNDED BY
Department of Energy (DOE)
Knolls Atomic Power Laboratory (KAPL)
APPLICANT(S) Brett W. Siebert (Schenectady, New York)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Brett W. Siebert (Schenectady, New York)
ABSTRACT A non-circular coolant passage is disclosed, which includes one or more walls axially defining a flow path; an inlet connecting to a first end of the flow path; and an exit connecting to a second end of the flow path, wherein a size of a passage cross-section varies in the axial direction. In certain exemplary embodiments the passage cross-section size varies uniformly, while in others the passage cross-section size varies incrementally. In certain exemplary embodiments, an angular orientation of the passage cross-section varies in the axial direction. The cross-section angular orientation can vary uniformly, incrementally, or a combination of both. In still other embodiments, both the size of the passage cross-section and the angular orientation of the passage cross-section vary in the axial direction. In these embodiments, the passage cross-section size and/or the angular orientation of the passage cross-section can vary uniformly, incrementally, and/or a combination of the two.
FILED Monday, September 09, 2013
APPL NO 14/020983
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 1/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302405 McGrane
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S) Shawn D. McGrane (Los Alamos, New Mexico)
ABSTRACT Disclosed herein are embodiments of devices comprising energetic materials capable of superdetonation and methods of making and using such devices. The devices disclosed herein comprise components, dimensions, and configurations optimized to utilize superdetonation velocities produced by the energetic materials disclosed herein.
FILED Tuesday, January 23, 2018
APPL NO 15/878233
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 1/02 (20130101)
F42B 3/00 (20130101)
F42B 3/08 (20130101)
F42B 12/10 (20130101)
F42B 12/20 (20130101)
F42B 12/207 (20130101)

Blasting
F42D 3/00 (20130101) Original (OR) Class
F42D 5/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302586 Sun et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jeong Yun Sun (Cambridge, Massachusetts);  Christoph Matthias Keplinger (Cambridge, Massachusetts);  Zhigang Suo (Lexington, Massachusetts);  George M. Whitesides (Newton, Massachusetts)
ABSTRACT A class of devices enabled by ionic conductors is highly stretchable, fully transparent to light of all colors, biocompatible or biodegradable, and capable of operation at frequencies beyond 10 kilohertz and voltages above 10 kilovolts. These devices enabled by ionic conductors can be used as large strain actuators, full-range loudspeakers, as strain or pressure sensors and as stretchable interconnects. The electromechanical transduction is achieved without electrochemical reaction. When large stretchability and high optical transmittance are required, the ionic conductors have lower sheet resistance than all existing electronic conductors.
FILED Thursday, April 10, 2014
APPL NO 14/768850
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/02 (20130101)
G01N 27/305 (20130101) Original (OR) Class
G01N 27/3335 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302614 Zografos et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) SafeTraces, Inc. (Oakland, California);  Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) SafeTraces, Inc. (Oakland, California);  Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Antonios Zografos (Oakland, California);  George Roy Farquar (Livermore, California)
ABSTRACT Food distributed to consumers through a distribution chain may be traced by tagging the food with DNA tags that identify the origin of the food, such as the grower, packer and other points of distribution, and their attributes. This makes it much quicker and easier to trace the food in case of food contamination or adulteration. Preferably these attributes indicate the field, location, crew and machine used to grow and process the food, and the dates of the various steps of food harvesting, processing and distribution. Natural or synthetic DNA pieces may be used to tag items, including food items. Multidigit binary or other types of bar codes may be represented by multiple types of DNA. Each digit of the bar code may be represented by one, two or more unique DNA pieces.
FILED Friday, January 16, 2015
APPL NO 14/599315
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 29/045 (20160801)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1065 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/686 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 2563/185 (20130101)
C12Q 2563/185 (20130101)
C12Q 2563/185 (20130101)
C12Q 2563/185 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/02 (20130101) Original (OR) Class
G01N 33/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302733 Walsh
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) VISTA CLARA INC. (Mukilteo, Washington)
ASSIGNEE(S) VISTA CLARA INC. (Mukilteo, Washington)
INVENTOR(S) David O. Walsh (Mukilteo, Washington)
ABSTRACT Technologies applicable to NMR spin-echo amplitude estimation are disclosed. Example methods may calibrate for distortion of a shape and estimated amplitude of measured NMR spin or gradient echoes. NMR spin or gradient echo measurements may be performed on a sample. The measured NMR spin or gradient echoes may be used to calculate an echo-shape calibration factor. The echo-shape calibration factor may estimate an effect of echo shape on estimated spin or gradient echo amplitude(s) of the NMR spin or gradient echoes. The echo-shape calibration factor may be used to correct for underestimation or overestimation of the spin or gradient echo amplitude(s).
FILED Monday, December 19, 2016
APPL NO 15/383840
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/081 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/441 (20130101)
G01R 33/448 (20130101)
G01R 33/583 (20130101) Original (OR) Class
G01R 33/4625 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303139 Chen et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Jie Chen (Carmel, Indiana);  Ali Razban (Carmel, Indiana);  Stanley Yung-Ping Chien (Zionsville, Indiana);  Amin Amini (Irvine, California);  Mustafa Saad Abdulwahhab Kamoona (Santa Clara, California);  Hamid Reza Piroozi (Fishers, Indiana)
ASSIGNEE(S) CREATIVE ESP INCORPORATED (Carmel, Indiana)
INVENTOR(S) Jie Chen (Carmel, Indiana);  Ali Razban (Carmel, Indiana);  Stanley Yung-Ping Chien (Zionsville, Indiana);  Amin Amini (Irvine, California);  Mustafa Saad Abdulwahhab Kamoona (Santa Clara, California);  Hamid Reza Piroozi (Fishers, Indiana)
ABSTRACT A system for managing performance of one or more electrical components in real-time includes one or more sensors to provide working conditions of one or more energy consuming devices. The system further includes one or more actuators coupled to and configured to control the one or more energy consuming devices. Additionally, the system includes a computing device in electrical communication with the one or more sensors and the one or more actuators. The system also includes a database capable of retaining an instruction program for the computing device. The computing device includes a processor that is configured to receive data from the one or more sensors, analyze data from the one or more sensors, and execute the instruction program received from the database in order to optimize operation of the one or more energy consuming devices based on one or more criteria.
FILED Wednesday, May 31, 2017
APPL NO 15/609780
ART UNIT 2117 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 13/00 (20130101)
G05B 15/00 (20130101)
G05B 15/02 (20130101) Original (OR) Class
G05B 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303472 Lowell et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Sunnyvale, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Daniel I. Lowell (Austin, Texas);  Manish Gupta (San Diego, California)
ABSTRACT Systems, apparatuses, and methods for implementing bufferless communication for redundant multithreading applications using register permutation are disclosed. In one embodiment, a system includes a parallel processing unit, a register file, and a scheduler. The scheduler is configured to cause execution of a plurality of threads to be performed in lockstep on the parallel processing unit. The plurality of threads include a first thread and a second thread executing on adjacent first and second lanes, respectively, of the parallel processing unit. The second thread is configured to perform a register permute operation from a first register location to a second register location in a first instruction cycle, with the second register location associated with the second processing lane. The second thread is configured to read from the second register location in a second instruction cycle, wherein the first and second instruction cycles are successive instruction cycles.
FILED Tuesday, November 22, 2016
APPL NO 15/359236
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/46 (20130101)
G06F 9/3824 (20130101)
G06F 9/3851 (20130101)
G06F 9/3861 (20130101)
G06F 9/3887 (20130101)
G06F 9/30032 (20130101) Original (OR) Class
G06F 11/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303602 Kayiran et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Sunnyvale, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Onur Kayiran (Sunnyvale, California);  Gabriel H. Loh (Bellevue, Washington);  Yasuko Eckert (Bellevue, Washington)
ABSTRACT A processing system includes at least one central processing unit (CPU) core, at least one graphics processing unit (GPU) core, a main memory, and a coherence directory for maintaining cache coherence. The at least one CPU core receives a CPU cache flush command to flush cache lines stored in cache memory of the at least one CPU core prior to launching a GPU kernel. The coherence directory transfers data associated with a memory access request by the at least one GPU core from the main memory without issuing coherence probes to caches of the at least one CPU core.
FILED Friday, March 31, 2017
APPL NO 15/475435
ART UNIT 2138 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/0804 (20130101)
G06F 12/0806 (20130101) Original (OR) Class
G06F 12/0817 (20130101)
G06F 2212/502 (20130101)
G06F 2212/1024 (20130101)
G06F 2212/1048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303697 Naegle et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  Lewis Rhodes Labs, Inc. (Concord, Massachusetts)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  Lewis Rhodes Labs, Inc. (Concord, Massachusetts)
INVENTOR(S) John H. Naegle (Albuquerque, New Mexico);  James Bradley Aimone (Albuquerque, New Mexico);  Frances S. Chance (Albuquerque, New Mexico);  Craig Michael Vineyard (Albuquerque, New Mexico);  David R. Follett (Boxborough, Massachusetts);  Pamela L. Follett (Boxborough, Massachusetts)
ABSTRACT A method for processing data is provided. Data is identified by a computer system. The data is processed in parallel by the computer system using temporal transformations to form pieces of temporal data. The pieces of temporal data are placed by the computer system in an order as the pieces of temporal data are generated by the temporal transformations to form a sequence of temporal data. The order of the sequence is based on a priority of when the pieces of temporal data should be processed, enabling performing an action.
FILED Thursday, June 25, 2015
APPL NO 14/749890
ART UNIT 2168 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/86 (20190101)
G06F 16/254 (20190101) Original (OR) Class
G06F 16/258 (20190101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 7/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303841 Ochoa et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Edward M. Ochoa (Powder Springs, Georgia);  Kristina Rodriguez Czuchlewski (Albuquerque, New Mexico)
ABSTRACT Various technologies pertaining to automatic relative volatility and relative amplitude detection are described herein. A spectral density of a geospatial temporal dataset is computed, and one or more frequencies of the dataset are identified. A volatility period of interest is calculated based upon the frequencies, and volatility thresholds are computed based upon the volatility period of interest. One or more periods of potential interest are detected in the dataset based upon the geospatial temporal data and the volatility thresholds. An indication of the periods of interest, an occurrence of an event captured in the dataset, or a prediction of an occurrence of an event that is of potential interest to an analyst is output.
FILED Tuesday, March 22, 2016
APPL NO 15/077584
ART UNIT 2898 — Semiconductors/Memory
CURRENT CPC
Electric Digital Data Processing
G06F 17/509 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304243 Ebeida
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Mohamed Salah Ebeida (Albuquerque, New Mexico)
ABSTRACT Described herein are technologies pertaining to generating a Voronoi mesh for an enclosed domain of arbitrarily many dimensions. An implicit Voronoi mesh is received that comprises locations of seeds in the domain. Neighbors of a seed are identified by extending a segment from the seed to the boundary of the domain and performing successive hyperplane trimming of the segment to identify a point on the facet of the Voronoi cell of the seed. A vertex of the cell can be identified by successively extending and trimming one or more additional spokes to identify points on a facet of the cell that are constrained to lie in a (d−n) space, where d is a number of dimensions of the domain and n is a number of iterations. A numerical simulation is performed based on the Voronoi mesh to generate simulation results in applications including surrogate modeling, global optimization, calibration, dimension reduction.
FILED Tuesday, June 27, 2017
APPL NO 15/634750
ART UNIT 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Electric Digital Data Processing
G06F 17/5009 (20130101)
G06F 2217/16 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6276 (20130101)
G06K 9/6286 (20130101)

Image Data Processing or Generation, in General
G06T 17/20 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304570 Cadell et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
APPLICANT(S) NuScale Power, LLC (Corvallis, Oregon)
ASSIGNEE(S) NuScale Power, LLC (Corvallis, Oregon)
INVENTOR(S) Seth Cadell (Corvallis, Oregon);  Tamas R. Liszkai (Corvallis, Oregon)
ABSTRACT Various embodiments are directed towards a nuclear latch assembly. The assembly includes a latch housing and a latch mechanism. The latch mechanism includes a projection member. The latch mechanism provides a biasing force on the projection member. Unless an opposing force on the projection member counterbalances the biasing force, the projection member at least partially projects from a surface of the latch housing. The assembly may include a biasing member that provides the biasing force on the projection member. The assembly may include a bolt. The bolt includes a longitudinal axis. A bore included in the housing is sized to receive the bolt. When the bore receives the bolt, the housing is rotatable about the longitudinal axis of the bolt. The latch mechanism includes a side bore that receives the projection member, the biasing member, and a disk intermediate the projection member and the biasing member.
FILED Friday, February 26, 2016
APPL NO 15/055336
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Nuclear Reactors
G21C 3/331 (20130101) Original (OR) Class
G21C 5/10 (20130101)
G21C 11/06 (20130101)
G21C 13/02 (20130101)
G21C 19/19 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 30/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304972 Shepherd et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) SUNPOWER CORPORATION (San Jose, California)
ASSIGNEE(S) SunPower Corporation (San Jose, California)
INVENTOR(S) Michael Shepherd (San Jose, California);  David D. Smith (Campbell, California)
ABSTRACT Solar cells with silicon oxynitride dielectric layers and methods of forming silicon oxynitride dielectric layers for solar cell fabrication are described. For example, an emitter region of a solar cell includes a portion of a substrate having a back surface opposite a light receiving surface. A silicon oxynitride (SiOxNy, 0<x, y) dielectric layer is disposed on the back surface of the portion of the substrate. A semiconductor layer is disposed on the silicon oxynitride dielectric layer.
FILED Friday, March 20, 2015
APPL NO 14/664759
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/02 (20130101) Original (OR) Class
H01L 31/18 (20130101)
H01L 31/0236 (20130101)
H01L 31/0682 (20130101)
H01L 31/1804 (20130101)
H01L 31/02002 (20130101)
H01L 31/02167 (20130101)
H01L 31/02245 (20130101)
H01L 31/02363 (20130101)
H01L 31/03682 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
Y02E 10/546 (20130101)
Y02E 10/547 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/521 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304977 Okandan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Murat Okandan (Edgewood, New Mexico);  Gregory N. Nielson (Albuquerque, New Mexico);  Jose Luis Cruz-Campa (Albuquerque, New Mexico);  Paul J. Resnick (Albuquerque, New Mexico);  Carlos Anthony Sanchez (Belen, New Mexico)
ABSTRACT A method, system and apparatus including a device cell having a top side, a bottom side and opposing side walls. A passivation layer is formed along the top side, the bottom side and opposing side walls of the device cell. The passivation layer serves to passivate the device cell and facilitate carrier collection around the device cell. An anti-reflective layer is formed over the passivation layer and an optical layer is formed on the top side of the device cell. The optical layer reflects light within the device cell. The apparatus may further include a reflective layer formed along the bottom side of the device cell, the reflective layer to reflect light internally within the device cell.
FILED Monday, May 11, 2015
APPL NO 14/709284
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/054 (20141201)
H01L 31/056 (20141201)
H01L 31/0682 (20130101)
H01L 31/1804 (20130101)
H01L 31/1892 (20130101)
H01L 31/02167 (20130101)
H01L 31/02168 (20130101)
H01L 31/02327 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304980 Yang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Peidong Yang (Kensington, California);  Chong Liu (Cambridge, Massachusetts);  Jinyao Tang (Emeryville, California);  Hao Ming Chen (Taipei, Taiwan);  Bin Liu (Albany, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Peidong Yang (Kensington, California);  Chong Liu (Cambridge, Massachusetts);  Jinyao Tang (Emeryville, California);  Hao Ming Chen (Taipei, Taiwan);  Bin Liu (Albany, California)
ABSTRACT This disclosure provides systems, methods, and apparatus related to solar water splitting. In one aspect, a structure includes a plurality of first nanowires, the plurality of first nanowires comprising an n-type semiconductor or a p-type semiconductor. The structure further includes a second nanowire, the second nanowire comprising the n-type semiconductor or the p-type semiconductor, the second nanowire being a different composition than the plurality of first nanowires. The second nanowire includes a first region and a second region, with the first region having a conductive layer disposed thereon, and each of the plurality of first nanowires being disposed on the conductive layer.
FILED Wednesday, April 22, 2015
APPL NO 14/692886
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/003 (20130101)
C25B 3/04 (20130101)
C25B 9/18 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0352 (20130101) Original (OR) Class
H01L 31/035272 (20130101)
H01L 31/035281 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304983 Kozodoy et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Glint Photonics, Inc. (Burlingame, California)
ASSIGNEE(S) Glint Photonics, Inc. (Burlingame, California)
INVENTOR(S) Peter Kozodoy (Palo Alto, California);  Christopher Gladden (San Mateo, California);  Michael Pavilonis (San Francisco, California);  Christopher Rhodes (Oakland, California)
ABSTRACT The system captures and concentrates sunlight for transmission to interior spaces or to a PV system. A solar collector uses arrayed refractive lenses and opposing concave focusing mirrors and a movable coupling sheet forming part of a lightguide. The transparent sheet contains small angled mirrors, where each angled mirror corresponds to a particular set of the lenses/focusing mirrors and is in the focal plane. The lightguide also includes a fluid surrounding the transparent sheet, and lower index cladding layers sandwich the fluid. The sheet is translated within the fluid by an actuator to position the angled mirrors at the focal points of the sunlight for maximum deflection of the sunlight to an edge of the lightguide for extraction to a light transmission system or to a PV system. A position sensor on the sheet provides feedback regarding the position of the angled mirrors relative to the focal points.
FILED Tuesday, October 25, 2016
APPL NO 15/333970
ART UNIT 2874 — Optics
CURRENT CPC
Non-portable Lighting Devices; Systems Thereof; Vehicle Lighting Devices Specially Adapted for Vehicle Exteriors
F21S 11/002 (20130101)

Solar Heat Collectors; Solar Heat Systems
F24S 23/00 (20180501)
F24S 23/12 (20180501)
F24S 23/30 (20180501)
F24S 23/70 (20180501)

Optical Elements, Systems, or Apparatus
G02B 6/003 (20130101)
G02B 6/0018 (20130101)
G02B 6/3538 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0543 (20141201)
H01L 31/0547 (20141201) Original (OR) Class

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 10/20 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/44 (20130101)
Y02E 10/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10304989 Albin et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) David Scott Albin (Denver, Colorado);  Wyatt Keith Metzger (Louisville, Colorado);  James Michael Burst (Lakewood, Colorado);  Eric Michael Colegrove (Denver, Colorado);  Joel Nathan Duenow (Golden, Colorado)
ABSTRACT Methods for growing and using large-grain templates are provided. According to an aspect of the invention, a method includes depositing a small-grain layer of a semiconductor material; treating the small-grain layer such that the small-grain layer becomes a large-grain layer; and growing an epitaxial layer of the semiconductor material on the large-grain layer. A ratio of an average grain size of the small-grain layer to a thickness of the small-grain layer is less than 1.0, and a ratio of an average grain size of the large-grain layer to a thickness of the large-grain layer is greater than 1.5.
FILED Friday, March 16, 2018
APPL NO 15/923307
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0248 (20130101)
H01L 21/02422 (20130101)
H01L 21/02491 (20130101)
H01L 21/02502 (20130101)
H01L 21/02513 (20130101)
H01L 21/02562 (20130101)
H01L 21/02595 (20130101)
H01L 21/02631 (20130101)
H01L 21/02634 (20130101)
H01L 21/02694 (20130101)
H01L 31/1828 (20130101) Original (OR) Class
H01L 31/1836 (20130101)
H01L 31/1864 (20130101)
H01L 31/1868 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305014 Boukai et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Akram Boukai (Mountain View, California);  Yuri Bunimovich (Williamsville, New York);  William A. Goddard (Pasadena, California);  James R. Heath (South Pasadena, California);  Jamil Tahir-Kheli (Los Angeles, California)
ABSTRACT Methods and devices for controlling thermal conductivity and thermoelectric power of semiconductor nanowires are described. The thermal conductivity and the thermoelectric power are controlled substantially independently of the electrical conductivity of the nanowires by controlling dimensions and doping, respectively, of the nanowires. A thermoelectric device comprising p-doped and n-doped semiconductor nanowire thermocouples is also shown, together with a method to fabricate alternately p-doped and n-doped arrays of silicon nanowires.
FILED Tuesday, October 27, 2015
APPL NO 14/924596
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/26 (20130101) Original (OR) Class
H01L 35/32 (20130101)
H01L 35/34 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305103 Thackeray et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Michael M. Thackeray (Naperville, Illinois);  Jason Croy (Plainfield, Illinois);  Khalil Amine (Oak Brook, Illinois);  Bryan T. Yonemoto (Westmont, Illinois);  Joong Sun Park (Woodridge, Illinois)
ABSTRACT A structurally inhomogeneous lithium metal oxide material having the Formula (I): y[xLi2MO3•(1-x)LiM′O2]•(1-y)Li1+dM″2−dO4; wherein 0≤x≤1; 0<y<1; 0≤d≤0.33; and wherein the Li1+dM″2−dO4 component comprises a spinel structure, and each of the Li2MO3 and the LiM′2 components thereof comprise layered structures. Each of M, M′, and M″ independently comprises one or more metal ions. The composition of the material of Formula (I) varies across the electrode particles by changing at least one of x, y, d, M, M′ and M″. Electrodes, cells and batteries comprising the lithium metal oxide material are also described.
FILED Tuesday, August 09, 2016
APPL NO 15/232188
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/364 (20130101)
H01M 4/505 (20130101) Original (OR) Class
H01M 4/525 (20130101)
H01M 10/052 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305114 Liu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Di-Jia Liu (Elmhurst, Illinois);  Shengqian Ma (Tampa, Florida);  Gabriel A. Goenaga (Knoxville, Tennessee)
ABSTRACT A method of preparing a nitrogen containing electrode catalyst by converting a high surface area metal-organic framework (MOF) material free of platinum group metals that includes a transition metal, an organic ligand, and an organic solvent via a high temperature thermal treatment to form catalytic active sites in the MOF. At least a portion of the contained organic solvent may be replaced with a nitrogen containing organic solvent or an organometallic compound or a transition metal salt to enhance catalytic performance. The electrode catalysts may be used in various electrochemical systems, including a proton exchange membrane fuel cell.
FILED Monday, September 08, 2014
APPL NO 14/479796
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/18 (20130101)
B01J 31/1691 (20130101)
B01J 31/1805 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/8605 (20130101)
H01M 4/8875 (20130101)
H01M 4/8882 (20130101)
H01M 4/9008 (20130101) Original (OR) Class
H01M 4/9041 (20130101)
H01M 8/10 (20130101)
H01M 2008/1095 (20130101)
H01M 2250/20 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/50 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 90/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305115 Liu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Di-Jia Liu (Naperville, Illinois);  Shengqian Ma (Chicago, Illinois);  Gabriel A. Goenaga (New York, New York);  Dan Zhao (Clementi, Singapore)
ABSTRACT A method of preparing a nitrogen containing electrode catalyst by converting a high surface area metal-organic framework (MOF) material free of platinum group metals that includes a transition metal, an organic ligand, and an organic solvent via a high temperature thermal treatment to form catalytic active sites in the MOF. At least a portion of the contained organic solvent may be replaced with a nitrogen containing organic solvent or an organometallic compound or a transition metal salt to enhance catalytic performance. The electrode catalysts may be used in various electrochemical systems, including an alkaline fuel cell.
FILED Friday, February 27, 2015
APPL NO 14/634581
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/18 (20130101)
B01J 31/1691 (20130101)
B01J 31/1805 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/8605 (20130101)
H01M 4/8882 (20130101)
H01M 4/9008 (20130101) Original (OR) Class
H01M 4/9016 (20130101)
H01M 4/9041 (20130101)
H01M 8/083 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305116 Tong et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Colorado School of Mines (Golden, Colorado);  CoorsTek, Inc. (Golden, Colorado)
ASSIGNEE(S) Colorado School of Mines (Golden, Colorado);  CoorsTek, Inc. (Golden, Colorado)
INVENTOR(S) Jianhua Tong (Golden, Colorado);  Meng Shang (Urbana, Illinois);  Ryan Patrick O'Hayre (Golden, Colorado);  Sophie Menzer (Lakewood, Colorado);  W. Grover Coors (Golden, Colorado)
ABSTRACT The present invention relates to a protonic ceramic fuel cell and a method of making the same. More specifically, the method relates to a cost-effective route which utilizes a single moderate-temperature (less than or equal to about 1400° C.) sintering step to achieve the sandwich structure of a PCFC single cell (dense electrolyte, porous anode, and porous cathode bone). The PCFC layers are stably connected together by the intergrowth of proton conducting ceramic phases. The resulted PCFC single cell exhibits excellent performance (about 450 mW/cm2 at about 500° C.) and stability (greater than about 50 days) at intermediate temperatures (less than or equal to about 600° C.). The present invention also relates to a two step method for forming a PCFC, and the resulting PCFC.
FILED Thursday, February 12, 2015
APPL NO 14/621091
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/8621 (20130101)
H01M 4/8828 (20130101)
H01M 4/8889 (20130101)
H01M 4/8892 (20130101)
H01M 4/9025 (20130101)
H01M 4/9033 (20130101) Original (OR) Class
H01M 4/9066 (20130101)
H01M 8/126 (20130101)
H01M 8/1213 (20130101)
H01M 8/1246 (20130101)
H01M 8/1253 (20130101)
H01M 2004/8689 (20130101)
H01M 2008/1293 (20130101)
H01M 2300/0074 (20130101)
H01M 2300/0077 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/525 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/56 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305133 Small et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Leo J. Small (Albuquerque, New Mexico);  Travis Mark Anderson (Albuquerque, New Mexico);  Harry Pratt (Albuquerque, New Mexico)
ABSTRACT Nonaqueous redox flow batteries (RFB) hold the potential for high energy density grid scale storage, though are often limited by the solubility of the redox-active species in their electrolytes. A systematic approach enables an increase the concentration of redox-active species in electrolytes for nonaqueous RFB, starting from a metal-coordination-cation-based ionic liquid. As an example, starting with an ionic liquid consisting of a metal coordination cation (MetIL), ferrocene-containing ligands and iodide anions can be substituted into the original MetIL structure, enabling a nearly 4× increase in capacity compared to original MetIL structure. Application of this strategy to other chemistries, optimizing electrolyte melting point and conductivity could yield >10 M redox-active electrons.
FILED Wednesday, May 17, 2017
APPL NO 15/597474
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/188 (20130101) Original (OR) Class
H01M 8/1016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305421 Darling et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Energy, United States Department of (Washington, District of Columbia)
ASSIGNEE(S) U.S. Department of Energy (Washington, D.C., None)
INVENTOR(S) Seth B Darling (Chicago, Illinois);  Omar Daniel Lopez (Chicago, Illinois)
ABSTRACT A solar cell system is formed with a dynamic surface relief grating. Movement members are actuated by a controller to produce a force on the reflective surface. The reflective surface deforms in response to the force creating a surface relief grating that can adapt to changing light conditions.
FILED Tuesday, June 28, 2016
APPL NO 15/194983
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/056 (20141201)
H01L 31/0547 (20141201)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 20/32 (20141201)
H02S 40/22 (20141201) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305868 Evans et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Nathaniel Evans (Orland Hills, Illinois);  Michael Thompson (Chicago, Illinois)
ABSTRACT Systems and methods for utilizing stream splitting Moving Target Defense (MTD) to provide enhanced computer system communication system security by splitting a data stream in to a plurality of paths is described. In some implementations, Stream splitting MTD, involves splitting a single data stream (e.g., TCP stream) into a plurality of discrete units, then sending and receiving those discrete units from and to different (ideally geographically disparate) receiving servers, with the stream being reassembled on the receiving end. The plurality of discrete units of data include resequencing data. The size of each discrete unit may vary depending on the specific implementation, even down to small unit sizes (e.g., a single packet).
FILED Friday, September 30, 2016
APPL NO 15/282875
ART UNIT 2435 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/166 (20130101)
H04L 63/0464 (20130101) Original (OR) Class
H04L 63/1441 (20130101)
H04L 65/605 (20130101)
H04L 69/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305932 Hong et al.
FUNDED BY
Department of Energy (DOE)
Office of Electricity (DOE-OE)
APPLICANT(S) ABB Inc. (Raleigh, North Carolina)
ASSIGNEE(S) ABB Inc. (Raleigh, North Carolina)
INVENTOR(S) Junho Hong (Cary, North Carolina);  Reynaldo Nuqui (Cary, North Carolina)
ABSTRACT Unique systems, methods, techniques and apparatuses of a substation phasor data concentrator (ssPDC) is disclosed herein. One exemplary embodiment is a method for operating an electrical substation including a merging unit (MU), a phasor measurement unit (PMU), and a substation phasor data concentrator (ssPDC). The method includes receiving, with the MU and the PMU, input information corresponding to a set of electrical characteristics of the electrical substation; measuring, with the MU, the input information; measuring, with the PMU, the input information; a and estimating, with the ssPDC, electrical characteristics of the electrical substation using the received false measurement and the one of the MU measurement and the PMU measurement, determining in substantially real time the false measurement does not correspond to the set of electrical characteristics using the estimated electric characteristics, and replacing the false measurement with the received the one of the MU measurement and the PMU measurement.
FILED Wednesday, December 21, 2016
APPL NO 15/386339
ART UNIT 2437 — Cryptography and Security
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 25/00 (20130101)
G01R 35/005 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 23/0286 (20130101)

Electric Digital Data Processing
G06F 21/55 (20130101)
G06F 21/577 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1416 (20130101)
H04L 63/1466 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305980 Gonzalez et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Juan Guillermo Gonzalez (Weston, Florida);  Santiago Andres Fonseca (Doral, Florida);  Rafael Camilo Nunez (Aventura, Florida)
ASSIGNEE(S) Intellectual Property Systems, LLC (, None)
INVENTOR(S) Juan Guillermo Gonzalez (Weston, Florida);  Santiago Andres Fonseca (Doral, Florida);  Rafael Camilo Nunez (Aventura, Florida)
ABSTRACT Data employed in computations amongst multiple processors in a computing system is processed so that less bits than a full representation of the data needs to be communicated yet all of the relevant information is communicated. More specifically, a sensitivity value is determined for various items of the data which reflect the number of bits in the data items that are not garbage bits, and only information in the data items that are indicated by the sensitivity value to not be garbage bits are necessarily effectively retained. At least the information that is not garbage bits and the corresponding associated sensitivity are packed together. The results of computations that are performed using the data items as at least one of the operands for the computation are associated with a sensitivity that is derived from the individual sensitivities of the operands used in the computation.
FILED Monday, August 29, 2016
APPL NO 15/249619
ART UNIT 2457 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/104 (20130101)
H04L 67/1095 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 10299707 Plumley et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) John B. Plumley (Albuquerque, New Mexico);  Erin D. Milligan (Placitas, New Mexico);  Marek Osinski (Albuquerque, New Mexico)
ABSTRACT The invention provides a quantum dot (QD) modified optical fiber-based biosensor which characterizes matrix metalloproteinase (MMP) enzyme activity at pain signaling sites in the central nervous system (CNS) in vivo. Related systems and peptide biomarker screening methods are also provided.
FILED Tuesday, April 18, 2017
APPL NO 15/489828
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1455 (20130101) Original (OR) Class
A61B 5/1459 (20130101)
A61B 5/4058 (20130101)
A61B 5/6852 (20130101)
A61B 5/6877 (20130101)
A61B 5/14735 (20130101)
A61B 2562/0233 (20130101)
A61B 2562/0285 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/588 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10299887 Yu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Qingsong Yu (Columbia, Missouri);  Hao Li (Columbia, Missouri);  Meng Chen (Columbia, Missouri)
ASSIGNEE(S) Nanova, Inc. (Columbia, Missouri);  Curators of the University of Missouri Office of Intellectual Property Admin. (Columbia, Missouri)
INVENTOR(S) Qingsong Yu (Columbia, Missouri);  Hao Li (Columbia, Missouri);  Meng Chen (Columbia, Missouri)
ABSTRACT The provision of dental restorations can be improved by generating a cold atmospheric plasma inside the mouth of the patient and then applying that cold atmospheric plasma onto a dental restoration site. The dental restoration site can be composed of either or both of dentin and enamel. Further, the provision of dental restorations can also be improved by introducing a dental adhesive onto a dental restoration site and treating it with a cold atmospheric plasma.
FILED Friday, April 23, 2010
APPL NO 12/766602
ART UNIT 3772 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Dentistry; Apparatus or Methods for Oral or Dental Hygiene
A61C 5/00 (20130101)
A61C 5/30 (20170201) Original (OR) Class
A61C 13/0001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300011 Khizroev et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Sakhrat Khizroev (Miami, Florida);  Tiffanie Stewart (Miami, Florida);  Abhignyan Nagesetti (Miami, Florida)
ASSIGNEE(S) The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S) Sakhrat Khizroev (Miami, Florida);  Tiffanie Stewart (Miami, Florida);  Abhignyan Nagesetti (Miami, Florida)
ABSTRACT Methods and devices for three-dimensional navigation of magnetic nanoparticles are provided. A method can comprise introducing high-anisotropy magnetic nanoparticles to a mammal and directing the high-anisotropy magnetic nanoparticles towards a target region of the mammal. Direction control is achieved by subjecting the high-anisotropy magnetic nanoparticles to an alternating signal comprising a uniform magnetic field pulse having a strength greater than a coercivity of the high-anisotropy magnetic nanoparticles and a magnetic gradient pulse having a highest strength that is less than the coercivity of the high-anisotropy magnetic nanoparticles and a location of a lowest strength at the target region of the mammal, and the direction of the uniform magnetic field pulse being in an opposite direction of the magnetic gradient pulse.
FILED Friday, September 14, 2018
APPL NO 16/131246
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/4839 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0009 (20130101) Original (OR) Class

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2/004 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300453 Leddy et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Iowa Research Foundation (Iowa City, Iowa)
ASSIGNEE(S)
INVENTOR(S) Johna Leddy (Iowa City, Iowa);  Chester G. Duda (West Liberty, Iowa);  Jacob Lyon (Davenport, Iowa);  William J. Leddy, III (Lakeway, Texas)
ABSTRACT A device which can increase the rates of interfacial reactions including heterogeneous electron transfer reactions, the device comprising at least one sono(electro)chemical cell adapted to hold a thin layer of condensed fluid which is optionally adapted to participate in a heterogeneous electron transfer reaction, wherein the cell is further adapted to provide an ultrasonic transducer face to propagate sound waves into the thin layer of condensed fluid, and wherein the cell is still further adapted with an opening to provide the thin layer of condensed fluid with at least one interface which provides for reflection of the sound waves from the interface back into the thin layer of condensed fluid. The cells are configured to provide for a thin layer operation as opposed to a bulk operation. In method embodiments, ultrasound is applied to the thin layer of condensed fluid. The application of ultrasound is carried out both without cooling of the cell and without pressurization of the cell. Methods of using the device include fuel cells and fuel cell electrodes. Systems having anodes and cathodes are also provided.
FILED Wednesday, October 15, 2014
APPL NO 14/515418
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/10 (20130101) Original (OR) Class
B01J 19/087 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/92 (20130101)
H01M 8/04 (20130101)
H01M 8/188 (20130101)
H01M 8/0637 (20130101)
H01M 8/1011 (20130101)
H01M 12/06 (20130101)
H01M 2008/1095 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/523 (20130101)
Y02E 60/566 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300599 Simaan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee);  Roger E. Goldman (New York, New York)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Nabil Simaan (Nashville, Tennessee);  Andrea Bajo (Fort Lauderdale, Florida);  James L. Netterville (Nashville, Tennessee);  C. Gaelyn Garrett (Nashville, Tennessee);  Roger E. Goldman (New York, New York)
ABSTRACT Methods and systems are described for controlling movement and an applied force at the tip of the continuum robot that includes a plurality of independently controlled segments along its length. An estimated force at the tip of the continuum robot is determined based on measurements of loads and positions of each segment. A reference position command and a force command are received from a user interface. The reference position command indicates a desired movement for the distal end of the continuum robot and the force command indicates a desired force to be applied by the tip of the continuum robot to a tissue surface. The position of the continuum robot is adjusted to cause the tip of the continuum robot to apply the desired force to the tissue surface based on the estimated force at the tip of the continuum robot, the reference position command, and the force command.
FILED Friday, January 06, 2017
APPL NO 15/399902
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/30 (20160201)
A61B 34/35 (20160201)
A61B 34/37 (20160201)
A61B 90/06 (20160201)
A61B 2017/00314 (20130101)
A61B 2017/00323 (20130101)
A61B 2034/301 (20160201)
A61B 2034/306 (20160201)
A61B 2090/064 (20160201)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1602 (20130101)
B25J 9/1625 (20130101) Original (OR) Class
B25J 9/1633 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 2219/40184 (20130101)
G05B 2219/40299 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/01 (20130101)
Y10S 901/30 (20130101)
Y10S 901/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301203 Wang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Xiaotang Wang (Hollywood, Florida);  Qinghao He (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Xiaotang Wang (Hollywood, Florida);  Qinghao He (Miami, Florida)
ABSTRACT The present invention provides efficient, economical, and environmentally-friendly compositions and methods for removing pollutants from water sources. In particular embodiments, the present invention provides compositions and methods for catalyzing the degradation of pharmaceutical pollutants in wastewater using the enzyme chloroperoxidase (CPO). Another embodiment provides a method of degrading pollutants in wastewater and other water sources. In specific embodiments, the claimed composition and method can be used to degrade pharmaceutical pollutants selected from the group consisting of: acetaminophen, carbamazepine, sulfamethazine, diclofenac, and naproxen.
FILED Tuesday, March 06, 2018
APPL NO 15/913419
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/76 (20130101)
C02F 1/722 (20130101)
C02F 1/725 (20130101)
C02F 1/766 (20130101)
C02F 3/342 (20130101) Original (OR) Class
C02F 2101/34 (20130101)
C02F 2101/36 (20130101)
C02F 2101/38 (20130101)
C02F 2101/40 (20130101)

Enzymes
C12Y 111/0101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301413 Jiang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) UNIVERSITY OF WASHINGTON (Seattle, Washington)
INVENTOR(S) Shaoyi Jiang (Redmond, Washington);  Shengfu Chen (Hangzhou, China PRC)
ABSTRACT Nonfouling copolymers and hydrogels comprising positively charged repeating units or latent positively charged repeating units and negatively charged units or latent positively charged units.
FILED Tuesday, April 28, 2015
APPL NO 14/698721
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/10 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 39/20 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 220/10 (20130101) Original (OR) Class
C08F 220/26 (20130101)
C08F 220/34 (20130101)
C08F 222/1006 (20130101)

Compositions of Macromolecular Compounds
C08L 51/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301445 Leventis et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Nicholas Leventis (Rolla, Missouri);  Chariklia Sotiriou-Leventis (Rolla, Missouri);  Sudhir Mulik (North Wales, Pennsylvania)
ASSIGNEE(S) Aerogel Technologies, LLC (Glendale, Wisconsin)
INVENTOR(S) Nicholas Leventis (Rolla, Missouri);  Chariklia Sotiriou-Leventis (Rolla, Missouri);  Sudhir Mulik (North Wales, Pennsylvania)
ABSTRACT Porous three-dimensional networks of polyurea and porous three-dimensional networks of carbon and methods of their manufacture are described. In an example, polyurea aerogels are prepared by mixing an triisocyanate with water and a triethylamine to form a sol-gel material and supercritically drying the sol-gel material to form the polyurea aerogel. Subjecting the polyurea aerogel to a step of pyrolysis may result in a three dimensional network having a carbon skeleton, yielding a carbon aerogel. The density and morphology of polyurea aerogels can be controlled by varying the amount of isocyanate monomer in the initial reaction mixture. A lower density in the aerogel gives rise to a fibrous morphology, whereas a greater density in the aerogel results in a particulate morphology. Polyurea aerogels described herein may also exhibit a reduced flammability.
FILED Friday, August 19, 2011
APPL NO 13/214061
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/00 (20170801)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/18 (20130101)
C08G 18/302 (20130101)
C08G 18/792 (20130101)
C08G 2101/0091 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/02 (20130101) Original (OR) Class
C08J 2205/026 (20130101)
C08J 2375/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301590 Kam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Lance C. Kam (New York, New York);  Helen H. Lu (New York, New York);  Sarah E. De Leo (Baton Rouge, Louisiana);  Keenan T. Bashour (Hillsborough, California);  Danielle Bogdanowicz (Cortlandt Manor, New York);  Philip Chuang (New York, New York)
ABSTRACT The disclosure provides for compositions, systems, and methods of cell expansion, stimulation and/or differentiation. The disclosure further provides for a mesh substrate and associated methods capable of stimulating cell expansion, for example, T cell or stem cell expansion. In another aspect, the disclosure provides for an electrospun mesh substrate and methods of using thereof comprising a silicone rubber composition, for example, polydimethylsiloxane, PLC, or combinations thereof.
FILED Friday, April 10, 2015
APPL NO 15/302475
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 5/0075 (20130101) Original (OR) Class
C12N 5/0636 (20130101)
C12N 5/0662 (20130101)
C12N 2531/00 (20130101)
C12N 2533/30 (20130101)
C12N 2533/40 (20130101)
C12N 2533/50 (20130101)

Knitting
D04B 21/12 (20130101)

Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials
D06M 15/15 (20130101)
D06M 2101/30 (20130101)
D06M 2101/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301597 Lipke et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Auburn University (Auburn, Alabama)
ASSIGNEE(S) Auburn University (Auburn, Alabama)
INVENTOR(S) Elizabeth A. Lipke (Auburn, Alabama);  Petra Kerscher (Auburn, Alabama);  Alexander J. Hodge (Auburn, Alabama)
ABSTRACT The present invention relates to the production of cell cultures and tissues from undifferentiated pluripotent stem cells using three-dimensional biomimetic materials. The resultant cell cultures or tissues can be used in any of a number of protocols including testing chemicals, compounds, and drugs. Further, the methods and compositions of the present invention further provide viable cell sources and novel cell delivery platforms that allow for replacement of diseased tissue and engraftment of new cardiomyocytes from a readily available in vitro source. The present invention includes novel methods required for the successful production of cell cultures and tissues, systems and components used for the same, and methods of using the resultant cell and tissue compositions.
FILED Friday, January 20, 2017
APPL NO 15/411807
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0657 (20130101) Original (OR) Class
C12N 5/0696 (20130101)
C12N 2500/46 (20130101)
C12N 2500/50 (20130101)
C12N 2501/999 (20130101)
C12N 2506/45 (20130101)
C12N 2513/00 (20130101)
C12N 2533/52 (20130101)
C12N 2533/54 (20130101)
C12N 2537/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301613 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Xiao Wang (Chandler, Arizona);  Kylie Standage-Beier (Phoenix, Arizona)
ABSTRACT The present invention relates to kits and methods of modifying the prokaryotic genome a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas system that utilized one nicking Cas nuclease and crRNAs. The kid and methods delete or replace portions of the prokaryotic genome. In some embodiments, an entire gene or multiple genes may be deleted or replaced.
FILED Friday, September 09, 2016
APPL NO 15/260788
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/01 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301745 D'Evelyn et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) SLT TECHNOLOGIES, INC. (Los Angeles, California)
ASSIGNEE(S) SLT TECHNOLOGIES, INC. (Los Angeles, California)
INVENTOR(S) Mark P. D'Evelyn (Santa Barbara, California);  Dirk Ehrentraut (Santa Barbara, California);  Wenkan Jiang (Corona, California);  Bradley C. Downey (Santa Barbara, California)
ABSTRACT An ultralow defect gallium-containing nitride crystal and methods of making ultralow defect gallium-containing nitride crystals are disclosed. The crystals are useful as substrates for light emitting diodes, laser diodes, transistors, photodetectors, solar cells, and photoelectrochemical water splitting for hydrogen generators.
FILED Tuesday, August 02, 2016
APPL NO 15/226552
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 7/105 (20130101)
C30B 25/02 (20130101)
C30B 25/18 (20130101)
C30B 25/20 (20130101)
C30B 29/403 (20130101)
C30B 29/406 (20130101)
C30B 33/00 (20130101)
C30B 33/06 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/045 (20130101)
H01L 29/2003 (20130101)
H01L 31/03044 (20130101)
H01L 33/32 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/3202 (20130101)
H01S 5/32341 (20130101)
H01S 2304/00 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/24355 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302586 Sun et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jeong Yun Sun (Cambridge, Massachusetts);  Christoph Matthias Keplinger (Cambridge, Massachusetts);  Zhigang Suo (Lexington, Massachusetts);  George M. Whitesides (Newton, Massachusetts)
ABSTRACT A class of devices enabled by ionic conductors is highly stretchable, fully transparent to light of all colors, biocompatible or biodegradable, and capable of operation at frequencies beyond 10 kilohertz and voltages above 10 kilovolts. These devices enabled by ionic conductors can be used as large strain actuators, full-range loudspeakers, as strain or pressure sensors and as stretchable interconnects. The electromechanical transduction is achieved without electrochemical reaction. When large stretchability and high optical transmittance are required, the ionic conductors have lower sheet resistance than all existing electronic conductors.
FILED Thursday, April 10, 2014
APPL NO 14/768850
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/02 (20130101)
G01N 27/305 (20130101) Original (OR) Class
G01N 27/3335 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302692 Ghosh et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Swaroop Ghosh (Tampa, Florida);  Cheng-Wei Lin (Seffner, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Swaroop Ghosh (Tampa, Florida);  Cheng-Wei Lin (Seffner, Florida)
ABSTRACT Various devices, methods and systems are provided for aging-sensitive chip authentication. In one example, among others, a chip includes a reference Schmitt trigger ring oscillator (STRO) configured to enter a sleep mode during operation of the chip; a stressed STRO; a VDD charge pump configured to boost a positive voltage supplied to the stressed STRO during operation of the chip; and/or a GND charge pump configured to under-drive a ground voltage supplied to the stressed STRO during operation of the chip. In another example, a method includes detecting activation of a chip including a reference STRO and a stressed STRO and, in response to the activation of the chip, initiating sleep mode operation of the reference STRO. In response to the activation of the chip, a VDD voltage supplied to the stressed STRO can be boosted and/or a GND voltage supplied to the stressed STRO can be under-driven.
FILED Thursday, June 21, 2018
APPL NO 16/014195
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 23/02 (20130101)
G01R 31/282 (20130101)
G01R 31/2832 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302816 Deierling et al.
FUNDED BY
National Science Foundation (NSF)
National Center for Atmospheric Research (NCAR)
Federally Funded Research and Development Center (FFRDC)
Operated by University Corporation for Atmospheric Research (UCAR) at Boulder, CO
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) University Corporation for Atmospheric Research (Boulder, Colorado)
ASSIGNEE(S) University Corporation for Atmiospheric Research (Boulder, Colorado)
INVENTOR(S) Wiebke Kristina Deierling (Boulder, Colorado);  Kyoko Ikeda (Longmont, Colorado);  Matthias Steiner (Boulder, Colorado)
ABSTRACT A method and system for determining and displaying lightning potential information is provided. The method includes receiving a radar data and temperature data for a grid location. If the radar data is above a radar threshold and the temperature data is below a temperature threshold a predictor field is computed. One or more predictor fields may be used to determine a lightning potential. Fuzzy logic may be used to combine predictor fields into a lightning potential. A grid of lightning potential values may be used to determine the lightning potential at a target location, or to indicate the lightning potential in a region outside an inner outlook region including the target location. A display may include an icon with an inner and outer portion displaying lightning potential in an inner and outer outlook region. A display may further include future lightning potential information.
FILED Wednesday, August 27, 2014
APPL NO 14/470205
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Meteorology
G01W 1/02 (20130101) Original (OR) Class
G01W 1/10 (20130101)
G01W 1/16 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 21/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303978 Kang et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Clinc, Inc. (Ann Arbor, Michigan)
ASSIGNEE(S) Clinc, Inc. (Ann Arbor, Michigan)
INVENTOR(S) Yiping Kang (Ann Arbor, Michigan);  Yunqi Zhang (Ann Arbor, Michigan);  Jonathan K. Kummerfeld (Ann Arbor, Michigan);  Parker Hill (Ann Arbor, Michigan);  Johann Hauswald (Ann Arbor, Michigan);  Michael A. Laurenzano (Ann Arbor, Michigan);  Lingjia Tang (Ann Arbor, Michigan);  Jason Mars (Ann Arbor, Michigan)
ABSTRACT Systems and methods of intelligent formation and acquisition of machine learning training data for implementing an artificially intelligent dialogue system includes constructing a corpora of machine learning test corpus that comprise a plurality of historical queries and commands sampled from production logs of a deployed dialogue system; configuring training data sourcing parameters to source a corpora of raw machine learning training data from remote sources of machine learning training data; calculating efficacy metrics of the corpora of raw machine learning training data, wherein calculating the efficacy metrics includes calculating one or more of a coverage metric value and a diversity metric value of the corpora of raw machine learning training data; using the corpora of raw machine learning training data to train the at least one machine learning classifier if the calculated coverage metric value of the corpora of machine learning training data satisfies a minimum coverage metric threshold.
FILED Thursday, September 27, 2018
APPL NO 16/143773
ART UNIT 2121 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 16/3329 (20190101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6256 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303982 Cox et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) David Cox (Somerville, Massachusetts);  Walter Scheirer (Somerville, Massachusetts);  Samuel Anthony (Cambridge, Massachusetts);  Ken Nakayama (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) David Cox (Somerville, Massachusetts);  Walter Scheirer (Somerville, Massachusetts);  Samuel Anthony (Cambridge, Massachusetts);  Ken Nakayama (Cambridge, Massachusetts)
ABSTRACT In various embodiments, training objects are classified by human annotators, psychometric data characterizing the annotation of the training objects is acquired, a human-weighted loss function based at least in part on the classification data and the psychometric data is computationally derived, and one or more features of a query object are computationally classified based at least in part on the human-weighted loss function.
FILED Wednesday, July 25, 2018
APPL NO 16/044822
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00288 (20130101)
G06K 9/627 (20130101)
G06K 9/6263 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305014 Boukai et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Akram Boukai (Mountain View, California);  Yuri Bunimovich (Williamsville, New York);  William A. Goddard (Pasadena, California);  James R. Heath (South Pasadena, California);  Jamil Tahir-Kheli (Los Angeles, California)
ABSTRACT Methods and devices for controlling thermal conductivity and thermoelectric power of semiconductor nanowires are described. The thermal conductivity and the thermoelectric power are controlled substantially independently of the electrical conductivity of the nanowires by controlling dimensions and doping, respectively, of the nanowires. A thermoelectric device comprising p-doped and n-doped semiconductor nanowire thermocouples is also shown, together with a method to fabricate alternately p-doped and n-doped arrays of silicon nanowires.
FILED Tuesday, October 27, 2015
APPL NO 14/924596
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/26 (20130101) Original (OR) Class
H01L 35/32 (20130101)
H01L 35/34 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305250 Bhattacharya et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Pallab Bhattacharya (Ann Arbor, Michigan);  Arnab S. Hazari (Hillsboro, Oregon)
ABSTRACT Photonic devices such as semiconductor lasers and photodetectors of various operating wavelengths are grown monolithically on a Silicon substrate, and formed of nanowire structures with quantum structures as active regions. A reduction of strain during fabrication results from the use of these nanowire structures, thereby allowing devices to operate for extended periods of time at elevated temperatures. Monolithic photonic devices and monolithic photonic integrated circuits formed on Silicon substrates are thus provided.
FILED Friday, November 10, 2017
APPL NO 15/809598
ART UNIT 2883 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/132 (20130101)
G02B 2006/12121 (20130101)
G02B 2006/12123 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/1443 (20130101)
H01L 27/1446 (20130101)
H01L 31/109 (20130101)
H01L 31/173 (20130101)
H01L 31/1848 (20130101)
H01L 31/1852 (20130101)
H01L 31/1856 (20130101)
H01L 31/02327 (20130101)
H01L 31/03044 (20130101)
H01L 31/03048 (20130101)
H01L 31/022408 (20130101)
H01L 31/035218 (20130101)
H01L 31/035227 (20130101)
H01L 31/035236 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/021 (20130101)
H01S 5/183 (20130101)
H01S 5/0262 (20130101) Original (OR) Class
H01S 5/0287 (20130101)
H01S 5/341 (20130101)
H01S 5/343 (20130101)
H01S 5/405 (20130101)
H01S 5/423 (20130101)
H01S 5/0425 (20130101)
H01S 5/3407 (20130101)
H01S 5/3409 (20130101)
H01S 5/34386 (20130101)
H01S 2304/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10306135 Velipasalar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Syracuse University (Syracuse, New York)
ASSIGNEE(S) Syracuse University (Syracuse, New York)
INVENTOR(S) Senem Velipasalar (Fayetteville, New York);  Mauricio Casares (Lincoln, Nebraska);  Akhan Almagambetov (Nunda, New York)
ABSTRACT There is set forth herein a system including a camera device. In one embodiment the system is operative to perform image processing for detection of an event involving a human subject. There is set forth herein in one embodiment, a camera equipped system employed for fall detection.
FILED Monday, February 13, 2017
APPL NO 15/431186
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0077 (20130101)
A61B 5/1117 (20130101)
A61B 5/7264 (20130101)

Electric Digital Data Processing
G06F 19/00 (20130101)

Pictorial Communication, e.g Television
H04N 1/00029 (20130101)
H04N 1/00042 (20130101)
H04N 5/2253 (20130101)
H04N 5/23206 (20130101)
H04N 5/23219 (20130101) Original (OR) Class
H04N 7/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10306206 Mourikis et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) The Regents of the University of California (Riverside, California)
ASSIGNEE(S) The Regents of The University of California (Oakland, California)
INVENTOR(S) Anastasios Mourikis (Riverside, California);  Mingyang Li (Riverside, California)
ABSTRACT A system and method for a 3-D motion estimation and online temporal calibration having one or more than one processor, one or more than one camera, one or more than one inertial sensor, a storage for storing data and instructions. The stored instructions comprise a filter estimation module, high-precision navigation instructions and consistent state estimates in scenarios involving features, with both constant and time-varying offsets from the filter estimation module.
FILED Wednesday, July 23, 2014
APPL NO 14/339276
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/165 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00671 (20130101)

Image Data Processing or Generation, in General
G06T 7/73 (20170101)
G06T 7/80 (20170101)
G06T 2207/10016 (20130101)
G06T 2207/30244 (20130101)

Pictorial Communication, e.g Television
H04N 5/247 (20130101)
H04N 13/204 (20180501) Original (OR) Class
H04N 13/296 (20180501)
H04N 2013/0085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10306532 Zhang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) WAYNE STATE UNIVERSITY (Detroit, Michigan)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Hongwei Zhang (Troy, Michigan);  Xiaohui Liu (Menlo Park, California);  Chuan Li (Detroit, Michigan)
ABSTRACT A Distributed sensing and control network includes multiple sensing/control nodes, each of which includes a controller. Each sensing/control node determines signal transmission/receipt scheduling based on a physical-ratio-k-scheduling (PRKS) protocol stored within the controller.
FILED Friday, March 14, 2014
APPL NO 14/776806
ART UNIT 2461 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 47/626 (20130101)

Wireless Communication Networks
H04W 40/16 (20130101) Original (OR) Class
H04W 40/20 (20130101)
H04W 72/1231 (20130101)
H04W 72/1242 (20130101)

Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use
Y02D 70/22 (20180101)
Y02D 70/34 (20180101)
Y02D 70/38 (20180101)
Y02D 70/144 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 10300603 Gorshechnikov et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Neurala, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Neurala, Inc. (Boston, Massachusetts)
INVENTOR(S) Anatoly Gorshechnikov (Newton, Massachusetts);  Massimiliano Versace (South Boston, Massachusetts);  Tim Barnes (Seattle, Washington)
ABSTRACT The systems and methods disclosed herein include a path integration system that calculates optic flow, infers angular velocity from the flow field, and incorporates this velocity estimate into heading calculations. The resulting system fuses heading estimates from accelerometers, gyroscopes, engine torques, and optic flow to determine self-localization. The system also includes a motivational system that implements a reward drive, both positive and negative, into the system. In some implementations, the drives can include: a) a curiosity drive that encourages exploration of new areas, b) a resource drive that attracts the agent towards the recharging base when the battery is low, and c) a mineral reward drive that attracts the agent towards previously explored scientific targets.
FILED Friday, November 20, 2015
APPL NO 14/947516
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1664 (20130101)
B25J 9/1694 (20130101) Original (OR) Class
B25J 9/1697 (20130101)

Electric Digital Data Processing
G06F 17/30241 (20130101)
G06F 17/30321 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/4619 (20130101)
G06K 9/4671 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/02 (20130101)
G06N 3/008 (20130101)
G06N 5/02 (20130101)

Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids
Y04S 10/54 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/01 (20130101)
Y10S 901/09 (20130101)
Y10S 901/46 (20130101)
Y10S 901/47 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10300675 Wusk et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINITRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Mary E. Wusk (Yorktown, Virginia);  Anthony M. Calomino (Cleveland, Ohio);  Kamran Daryabeigi (Virginia Beach, Virginia);  Walter E. Bruce, III (Yorktown, Virginia);  Joshua M. Fody (Hampton, Virginia);  Stephen D. Miller (Flagstaff, Arizona);  Steven P. Vague (Flagstaff, Arizona)
ABSTRACT A portable thermal protection system is provided for protecting equipment, facilities, and personnel in a region from a high intensity incident heat source. The system can be formed as a sleeping bag, a tent, a blanket, a sleeping bag, a vertical barrier, a curtain, a flexible rollup doorway, or a wrap. The system includes an outer textile layer first layer, an insulator second layer, and a non-porous film third layer which forms a gas barrier. Some embodiments include a fourth layer formed of a material to provide radiation protection. In some embodiments, the first and/or second layers are integrally formed with the materials that reflects radiation. The layers are joined together by high-temperature adhesives, stitching, needling, or tacking.
FILED Friday, February 10, 2017
APPL NO 15/429239
ART UNIT 1781 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/02 (20130101)
B32B 5/06 (20130101) Original (OR) Class
B32B 5/22 (20130101)
B32B 5/024 (20130101)
B32B 5/24 (20130101)
B32B 5/026 (20130101)
B32B 5/26 (20130101)
B32B 7/08 (20130101)
B32B 7/12 (20130101)
B32B 15/04 (20130101)
B32B 15/12 (20130101)
B32B 15/14 (20130101)
B32B 15/20 (20130101)
B32B 27/06 (20130101)
B32B 27/10 (20130101)
B32B 27/12 (20130101)
B32B 27/36 (20130101)
B32B 27/281 (20130101)
B32B 27/285 (20130101)
B32B 27/288 (20130101)
B32B 27/322 (20130101)
B32B 29/02 (20130101)
B32B 2250/03 (20130101)
B32B 2250/04 (20130101)
B32B 2250/05 (20130101)
B32B 2255/02 (20130101)
B32B 2255/10 (20130101)
B32B 2255/205 (20130101)
B32B 2262/101 (20130101)
B32B 2262/105 (20130101)
B32B 2262/106 (20130101)
B32B 2264/108 (20130101)
B32B 2307/304 (20130101)
B32B 2307/416 (20130101)
B32B 2307/546 (20130101)
B32B 2307/718 (20130101)
B32B 2307/732 (20130101)
B32B 2307/3065 (20130101)
B32B 2307/7242 (20130101)
B32B 2571/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301041 Shao et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Michael Shao (Pasadena, California);  Shanti R. Rao (Altadena, California);  Bijan Nemati (Madison, Alabama);  Navtej Singh Saini (Pasadena, California);  Russell Edward Trahan, III (Los Angeles, California);  Thomas A. Werne (Pasadena, California);  Chengxing Zhai (La Canada Flintridge, California)
ABSTRACT Systems and methods for tracking moving objects in accordance with embodiments of the invention are disclosed. In one embodiment of the invention, an object tracking system comprises a processor, a communications interface, and a memory configured to store an object tracking application. The object tracking application configures the processor to receive a sequence of images; estimate and subtract background pixel values from pixels in a sequence of images; compute sets of summed intensity values for different per frame pixel offsets from a sequence of images; identify summed intensity values from a set of summed intensity values exceeding a threshold; cluster identified summed intensity values exceeding the threshold corresponding to single moving objects; and identify a location of at least one moving object in an image based on at least one summed intensity value cluster.
FILED Friday, June 09, 2017
APPL NO 15/619260
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Aeroplanes; Helicopters
B64C 39/024 (20130101)
B64C 2201/127 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 47/08 (20130101) Original (OR) Class
B64D 2205/00 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 3/00 (20130101)

Image Data Processing or Generation, in General
G06T 7/254 (20170101)
G06T 2207/10016 (20130101)

Pictorial Communication, e.g Television
H04N 5/23238 (20130101)
H04N 5/23254 (20130101)
H04N 5/23277 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/823 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301043 Shoer et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Naval Nuclear Laboratory (NNL)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts)
ASSIGNEE(S) THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts)
INVENTOR(S) Joseph Shoer (Cambridge, Massachusetts);  Leena Singh (Lexington, Massachusetts);  Sungyung Lim (Acton, Massachusetts);  Timothy Henderson (Ashland, Massachusetts)
ABSTRACT A conical scanning method and system is provided for orienting a spacecraft with respect to a source. The system includes a spacecraft and an incidence angle sensor secured to the spacecraft to sense a signal from a source. The incidence angle sensor has a boresight that is canted with respect to the principal axis. A processor communicates with actuators on the spacecraft to adjust an attitude of the spacecraft based on information received from the incidence angle sensor and to thereby align a principal axis of the spacecraft with a direction from the spacecraft to the source. The method and system can also rely on information received from source presence sensors. The source may be the Sun, or a non-solar signal source.
FILED Wednesday, November 23, 2016
APPL NO 15/360545
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/36 (20130101)
B64G 1/363 (20130101) Original (OR) Class
B64G 2001/245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302496 Corrochano
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) NASA SOLUTIONS, LLC (Grayslake, Illinois)
ASSIGNEE(S) NASA SOLUTIONS, LLC (Grayslake, Illinois)
INVENTOR(S) Denis Corrochano (Algonquin, Illinois)
ABSTRACT A method and apparatus for determining a color and brightness of an LED, when the LED is biased with a current pulse. The apparatus includes a sensor having a plurality of filters and an output probe connected to the sensor, the output probe providing a color output and a brightness output in a single signal. The sensor may further include an input probe connected to the sensor providing power and a ground probe connected to the sensor providing a grounded connection to the sensor. The plurality of filters in the sensor are preferably configured in a matrix array of color receptors having different colors. The method of this invention utilizes pulsing/dynamic sampling to determine a frequency and/or a brightness of the LED output.
FILED Thursday, February 09, 2017
APPL NO 15/428948
ART UNIT 2877 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/0204 (20130101)
G01J 1/0492 (20130101)
G01J 3/0264 (20130101)
G01J 3/505 (20130101) Original (OR) Class
G01J 3/513 (20130101)
G01J 2001/4252 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302556 Yost et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) William T. Yost (Newport News, Virginia);  Daniel F. Perey (Yorktown, Virginia)
ABSTRACT Systems, methods, instruments and devices of the various embodiments enable improved characterization and comparison of the level and species of surface contaminants from photo-induced emission analysis. The various embodiments may provide flexibility for calculating and analyzing the time-dependence of emission efficiencies. Irregular and heterogeneous surfaces, including regionally multiply-connected surface compositions, may be analyzed according to the various embodiments, and the various embodiments include techniques that support specific contaminant identification. Various embodiment focusing techniques may enhance assessment of spatially differential regional analysis of the substrate for more critical applications. The various embodiments may also include differential comparison with reference surfaces, either through differential comparison while scanning, or by comparison to digitally stored responses to known contaminants.
FILED Thursday, July 14, 2016
APPL NO 15/210444
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/33 (20130101)
G01N 21/272 (20130101) Original (OR) Class
G01N 23/2273 (20130101)
G01N 2201/062 (20130101)
G01N 2201/068 (20130101)
G01N 2201/06113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10302759 Arteaga
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Ricardo A Arteaga (Lancaster, California)
ABSTRACT The present invention proposes an automatic dependent surveillance broadcast (ADS-B) architecture and process, in which priority aircraft and ADS-B IN and radar traffic information are included in the transmission of data through the telemetry communications to a remote ground control station. The present invention further proposes methods for displaying general aviation traffic information in three and/or four dimension trajectories using an industry standard Earth browser for increased situation awareness and enhanced visual acquisition of traffic for conflict detection. The present invention enable the applications of enhanced visual acquisition of traffic, traffic alerts, and en-route and terminal surveillance used to augment pilot situational awareness through ADS-B IN display and information in three or four dimensions for self-separation awareness.
FILED Monday, May 09, 2016
APPL NO 15/149451
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/003 (20130101)
G01S 13/86 (20130101)
G01S 13/9303 (20130101) Original (OR) Class
G01S 19/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303966 Coulter et al.
FUNDED BY
Department of Homeland Security (DHS)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) San Diego State University Research Foundation (San Diego, California)
ASSIGNEE(S) SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION (San Diego, California)
INVENTOR(S) Lloyd Lawrence Arthur Coulter (Escondido, California);  Douglas A. Stow (San Diego, California)
ABSTRACT A method for collecting and processing remotely sensed imagery in order to achieve precise spatial co-registration (e.g., matched alignment) between multi-temporal image sets is presented. Such precise alignment or spatial co-registration of imagery can be used for change detection, image fusion, and temporal analysis/modeling. Further, images collected in this manner may be further processed in such a way that image frames or line arrays from corresponding photo stations are matched, co-aligned and if desired merged into a single image and/or subjected to the same processing sequence. A second methodology for automated detection of moving objects within a scene using a time series of remotely sensed imagery is also presented. Specialized image collection and preprocessing procedures are utilized to obtain precise spatial co-registration (image registration) between multitemporal image frame sets. In addition, specialized change detection techniques are employed in order to automate the detection of moving objects.
FILED Monday, April 23, 2018
APPL NO 15/960298
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0063 (20130101)
G06K 9/3216 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 3/0093 (20130101)
G06T 7/33 (20170101)
G06T 7/254 (20170101)
G06T 2207/10032 (20130101)
G06T 2207/30181 (20130101)
G06T 2207/30212 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305158 Sherrer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Nuvotronics, Inc. (Radford, Virginia)
ASSIGNEE(S) CUBIC CORPORATION (San Diego, California)
INVENTOR(S) David Sherrer (Cary, North Carolina);  Jean-Marc Rollin (Chapel Hill, North Carolina);  Kenneth Vanhille (Cary, North Carolina);  Marcus Oliver (Durham, North Carolina);  Steven E. Huettner (Tucson, Arizona)
ABSTRACT An apparatus comprising a first power combiner/divider network and a second power combiner/divider network. The first power combiner/divider network splits a first electromagnetic signal into split signals that are connectable to signal processor(s). The second power combiner/divider network combines processed signals into a second electromagnetic signal. The apparatus includes a three-dimensional coaxial microstructure.
FILED Friday, November 10, 2017
APPL NO 15/809701
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 3/06 (20130101)
H01P 5/12 (20130101) Original (OR) Class
H01P 5/183 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305606 Chang et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Mau-Chung Frank Chang (Los Angeles, California);  Yanghyo Kim (Los Angeles, California);  Adrian J. Tang (Pasadena, California)
ABSTRACT Communication between a wireless base-station and a microwave reflector link are enhanced by feeding back a portion of the transmitter signal, adjusted for phase and amplitude, to cancel ambient reflection blocker signals being received at the base-station. The microwave reflector link does not utilize a transmitter gain stage, but communicates data back to the base-station in response to modulating the reflections of its antenna (e.g., in gain and/or phase). The disclosure aids in the proper amplification and processing of reflection signals from the microwave reflector link, by canceling out the blocking signals which arise as background objects reflect transmitter signal energy back to the base-station.
FILED Tuesday, April 18, 2017
APPL NO 15/490156
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/32 (20130101)

Antennas, i.e Radio Aerials
H01Q 11/12 (20130101)

Transmission
H04B 1/10 (20130101)
H04B 1/40 (20130101)
H04B 15/005 (20130101) Original (OR) Class

Selecting
H04Q 5/22 (20130101)

Wireless Communication Networks
H04W 84/02 (20130101)
H04W 88/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305980 Gonzalez et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Juan Guillermo Gonzalez (Weston, Florida);  Santiago Andres Fonseca (Doral, Florida);  Rafael Camilo Nunez (Aventura, Florida)
ASSIGNEE(S) Intellectual Property Systems, LLC (, None)
INVENTOR(S) Juan Guillermo Gonzalez (Weston, Florida);  Santiago Andres Fonseca (Doral, Florida);  Rafael Camilo Nunez (Aventura, Florida)
ABSTRACT Data employed in computations amongst multiple processors in a computing system is processed so that less bits than a full representation of the data needs to be communicated yet all of the relevant information is communicated. More specifically, a sensitivity value is determined for various items of the data which reflect the number of bits in the data items that are not garbage bits, and only information in the data items that are indicated by the sensitivity value to not be garbage bits are necessarily effectively retained. At least the information that is not garbage bits and the corresponding associated sensitivity are packed together. The results of computations that are performed using the data items as at least one of the operands for the computation are associated with a sensitivity that is derived from the individual sensitivities of the operands used in the computation.
FILED Monday, August 29, 2016
APPL NO 15/249619
ART UNIT 2457 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/104 (20130101)
H04L 67/1095 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10306155 Jhabvala et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Murzban D. Jhabvala (Clarksville, Maryland);  Donald E. Jennings (College Park, Maryland);  Compton J. Tucker (Washington, District of Columbia)
ABSTRACT A dual band infrared imaging system self-contained to fit within a small spacecraft is provided. The imaging system uses a detector array cooled by a mini cryocooler, and includes telescope optics and two bandpass filters for fire detection and thermal and evapotranspiration Earth science.
FILED Tuesday, June 28, 2016
APPL NO 15/194835
ART UNIT 2482 — Recording and Compression
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/66 (20130101)
B64G 1/1021 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/208 (20130101)
G02B 17/0808 (20130101)

Pictorial Communication, e.g Television
H04N 5/33 (20130101) Original (OR) Class
H04N 5/23245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 10303735 Kaul et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Himanshu Kaul (Portland, Oregon);  Mark A. Anders (Hillsboro, Oregon);  Sanu K. Mathew (Hillsboro, Oregon)
ABSTRACT Systems, apparatuses, and methods for k-nearest neighbor (KNN) searches are described. In particular, embodiments of a KNN accelerator and its uses are described. In some embodiments, the KNN accelerator includes a plurality of vector partial distance computation circuits each to calculate a partial sum, a minimum sort network to sort partial sums from the plurality of vector partial distance computation circuits to find k nearest neighbor matches and a global control circuit to control aspects of operations of the plurality of vector partial distance computation circuits.
FILED Wednesday, November 18, 2015
APPL NO 14/944828
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 16/90335 (20190101)
G06F 17/10 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00986 (20130101)
G06K 9/6276 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305251 Liang et al.
FUNDED BY
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S) HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S) Di Liang (Palo Alto, California);  Yingtao Hu (Palo Alto, California)
ABSTRACT According to an example of the present disclosure a semiconductor laser diode includes a layer of graphene between an active laser region and a semiconductor substrate structure. The semiconductor laser diode may further include a first pair of electrodes to apply a potential difference across the active laser region and a second pair of electrodes to apply a potential difference across the layer of graphene.
FILED Wednesday, May 11, 2016
APPL NO 15/151647
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/021 (20130101)
H01S 5/026 (20130101)
H01S 5/0085 (20130101)
H01S 5/0265 (20130101) Original (OR) Class
H01S 5/0607 (20130101)
H01S 5/1032 (20130101)
H01S 5/1071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305805 Flajslik et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Mario Flajslik (Hudson, Massachusetts);  Eric R. Borch (Fort Collins, Colorado);  Michael A. Parker (Santa Clara, California)
ABSTRACT Technologies for adaptive routing based on aggregated congestion information include a network switch that includes a plurality of output ports. The network switch is configured to determine a maximum local occupancy count for each output port based on a maximum local occupancy count of output buffer queues of each output port, a local congestion value based on the maximum local occupancy count, and a remote congestion value for a corresponding remote input buffer queue of a remote computing device communicatively coupled to a corresponding output port. The network switch is further configured to determine, for each output port, a total congestion value as a function of the local congestion value and the remote congestion value and enqueue the network packet into one of the output buffer queues of one of the output ports based on the total congestion values of the output ports. Other embodiments are described herein.
FILED Friday, July 01, 2016
APPL NO 15/200442
ART UNIT 2412 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 47/11 (20130101)
H04L 47/30 (20130101)
H04L 47/125 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305921 Gao et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Jing Gao (Buffalo, New York);  Deepak Turaga (Yorktown Heights, New York);  Long H. Vu (Yorktown Heights, New York);  Houping Xiao (Buffalo, New York)
ABSTRACT A network security apparatus includes a packet detector detecting transmission of data packets between a plurality of hosts and a plurality of domains and defining a plurality of links therefrom. A model builder circuit receives the plurality of links from the packet detector, receives ground truth information labeling one or more of the plurality of hosts or one or more of the plurality of domains as benign or malicious, generates predictive models from the received links and ground truth information, and stores generated predictive models in a predictive model database. An anomaly detector circuit retrieves the generated predictive models from the predictive model database and uses the predictive models to label each of the plurality of hosts and plurality of domains, that have not previously been labeled by the ground truth information, as benign or malicious.
FILED Thursday, April 28, 2016
APPL NO 15/141127
ART UNIT 2494 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/552 (20130101)
G06F 21/577 (20130101)

Computer Systems Based on Specific Computational Models
G06N 99/00 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 43/12 (20130101)
H04L 43/062 (20130101)
H04L 63/0227 (20130101)
H04L 63/1425 (20130101) Original (OR) Class
H04L 63/1433 (20130101)
H04L 63/1466 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10306052 Lack
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) Invincea, Inc. (Fairfax, Virginia)
ASSIGNEE(S) Invincea, Inc. (Fairfax, Virginia)
INVENTOR(S) Michael Nathan Lack (Arlington, Virginia)
ABSTRACT An apparatus includes a memory of a mobile compute device, and a hardware processor of the mobile compute device. The hardware processor is configured to implement an operating system and an authentication module. The operating system is configured to receive a first authentication identifier, and is also configured to authorize use of the mobile compute device based on the first authentication identifier meeting a first criterion. The authentication module is configured to, in response to the operating system authorizing use of the mobile compute device, disable at least one function of the mobile compute device and request a second authentication identifier. The authentication module is also configured to receive the second authentication identifier. The authentication module is also configured to enable the at least one function in response to the second authentication identifier meeting a second criterion.
FILED Monday, June 26, 2017
APPL NO 15/632808
ART UNIT 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/3247 (20130101)
H04L 63/08 (20130101)

Telephonic Communication
H04M 1/72577 (20130101) Original (OR) Class

Wireless Communication Networks
H04W 4/80 (20180201)
H04W 12/04 (20130101)
H04W 12/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 10301358 Looby et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Collagen Medical, LLC (Boston, Massachusetts)
ASSIGNEE(S) Collagen Medical, LLC (Boston, Massachusetts)
INVENTOR(S) Richard J. Looby (Reading, Massachusetts);  Peter D. Caravan (Cambridge, Massachusetts);  Thomas J. McMurry (Winchester, Massachusetts)
ABSTRACT Compounds and methods for imaging and/or assessing collagen are described. The compounds can include collagen binding peptides.
FILED Wednesday, June 29, 2016
APPL NO 15/196626
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/14 (20130101)
A61K 49/085 (20130101)

Peptides
C07K 7/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303978 Kang et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Clinc, Inc. (Ann Arbor, Michigan)
ASSIGNEE(S) Clinc, Inc. (Ann Arbor, Michigan)
INVENTOR(S) Yiping Kang (Ann Arbor, Michigan);  Yunqi Zhang (Ann Arbor, Michigan);  Jonathan K. Kummerfeld (Ann Arbor, Michigan);  Parker Hill (Ann Arbor, Michigan);  Johann Hauswald (Ann Arbor, Michigan);  Michael A. Laurenzano (Ann Arbor, Michigan);  Lingjia Tang (Ann Arbor, Michigan);  Jason Mars (Ann Arbor, Michigan)
ABSTRACT Systems and methods of intelligent formation and acquisition of machine learning training data for implementing an artificially intelligent dialogue system includes constructing a corpora of machine learning test corpus that comprise a plurality of historical queries and commands sampled from production logs of a deployed dialogue system; configuring training data sourcing parameters to source a corpora of raw machine learning training data from remote sources of machine learning training data; calculating efficacy metrics of the corpora of raw machine learning training data, wherein calculating the efficacy metrics includes calculating one or more of a coverage metric value and a diversity metric value of the corpora of raw machine learning training data; using the corpora of raw machine learning training data to train the at least one machine learning classifier if the calculated coverage metric value of the corpora of machine learning training data satisfies a minimum coverage metric threshold.
FILED Thursday, September 27, 2018
APPL NO 16/143773
ART UNIT 2121 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 16/3329 (20190101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6256 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305980 Gonzalez et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Juan Guillermo Gonzalez (Weston, Florida);  Santiago Andres Fonseca (Doral, Florida);  Rafael Camilo Nunez (Aventura, Florida)
ASSIGNEE(S) Intellectual Property Systems, LLC (, None)
INVENTOR(S) Juan Guillermo Gonzalez (Weston, Florida);  Santiago Andres Fonseca (Doral, Florida);  Rafael Camilo Nunez (Aventura, Florida)
ABSTRACT Data employed in computations amongst multiple processors in a computing system is processed so that less bits than a full representation of the data needs to be communicated yet all of the relevant information is communicated. More specifically, a sensitivity value is determined for various items of the data which reflect the number of bits in the data items that are not garbage bits, and only information in the data items that are indicated by the sensitivity value to not be garbage bits are necessarily effectively retained. At least the information that is not garbage bits and the corresponding associated sensitivity are packed together. The results of computations that are performed using the data items as at least one of the operands for the computation are associated with a sensitivity that is derived from the individual sensitivities of the operands used in the computation.
FILED Monday, August 29, 2016
APPL NO 15/249619
ART UNIT 2457 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/104 (20130101)
H04L 67/1095 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 10301191 Davis et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) University of Maryland (College Park, Maryland);  Low Impact Development Design Group, LLC (Beltsville, Maryland);  The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) UNIVERSITY OF MARYLAND (College Park, Maryland);  LOW IMPACT DEVELOPMENT DESIGN GROUP, LLC (Beltsville, Maryland);  The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Allen P. Davis (Laurel, Maryland);  Neil A. Weinstein (Silver Spring, Maryland);  Rufus L. Chaney (Beltsville, Maryland)
ABSTRACT A filtration system and method are provided for removing suspended solids and other affiliated pollutants from stormwater runoff and any other contaminated water. The filtration system and method utilize a filtration medium including steel slag. By improving or replacing a conventional filtration media, such as a sand filtration system, with a filtration medium including steel slag, the removal efficiency of suspended solids and affiliated pollutants is improved and the lifespan of the filtration system is lengthened.
FILED Thursday, August 27, 2015
APPL NO 14/837730
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 39/02 (20130101)
B01D 39/06 (20130101)
B01D 39/08 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/281 (20130101) Original (OR) Class
C02F 1/286 (20130101)
C02F 1/288 (20130101)
C02F 3/327 (20130101)
C02F 2101/20 (20130101)
C02F 2101/105 (20130101)
C02F 2103/001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301661 Obendorf et al.
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
APPLICANT(S) Cornell Research Foundation, Inc. (Ithaca, New York)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Ralph L. Obendorf (Ithaca, New York);  Takashi Ueda (Fort Myers, Florida)
ABSTRACT The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analog, an insulin mediator homolog, or an insulin mediator inhibitor is also described. The method includes providing a fagopyritol synthase, providing a substrate comprising a galactosyl donor and a galactosyl acceptor, and combining the fagopyritol synthase with the substrate under conditions effective produce a fagopyritol, an insulin mediator, an insulin mediator analog, an insulin mediator homolog, or an insulin mediator inhibitor.
FILED Wednesday, February 14, 2018
APPL NO 15/896517
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1051 (20130101)
C12N 15/8245 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/26 (20130101)
C12P 19/46 (20130101) Original (OR) Class

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/52 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 10300313 Baz et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) University of Maryland, College Park Office of Technology Commercialization (College Park, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
INVENTOR(S) Amr M. Baz (Rockville, Maryland);  Marino diMarzo (Bethesda, Maryland)
ABSTRACT A method and devices are described, in which a transformable fiber at a first crystal structure is shaped from its pre-determined configuration into a new shaped configuration. The new shaped configuration of the transformable fiber is inserted into a cavity of a heat and fire protective item. The new shaped configuration of the transformable fiber is heated to above its transformation temperature to a second crystal structure. The heating transforms the new shaped configuration to its pre-determined configuration, wherein the pre-determined configuration forms an air pocket within the heat and fire protective item. The transformable fiber is cooled below its transformation temperature to revert the transformable fiber back to the new shaped configuration at the first crystal structure.
FILED Friday, March 15, 2013
APPL NO 13/836099
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Outerwear; Protective Garments; Accessories
A41D 31/0027 (20130101)

Devices, Apparatus or Methods for Life-saving
A62B 17/003 (20130101) Original (OR) Class

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10303966 Coulter et al.
FUNDED BY
Department of Homeland Security (DHS)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) San Diego State University Research Foundation (San Diego, California)
ASSIGNEE(S) SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION (San Diego, California)
INVENTOR(S) Lloyd Lawrence Arthur Coulter (Escondido, California);  Douglas A. Stow (San Diego, California)
ABSTRACT A method for collecting and processing remotely sensed imagery in order to achieve precise spatial co-registration (e.g., matched alignment) between multi-temporal image sets is presented. Such precise alignment or spatial co-registration of imagery can be used for change detection, image fusion, and temporal analysis/modeling. Further, images collected in this manner may be further processed in such a way that image frames or line arrays from corresponding photo stations are matched, co-aligned and if desired merged into a single image and/or subjected to the same processing sequence. A second methodology for automated detection of moving objects within a scene using a time series of remotely sensed imagery is also presented. Specialized image collection and preprocessing procedures are utilized to obtain precise spatial co-registration (image registration) between multitemporal image frame sets. In addition, specialized change detection techniques are employed in order to automate the detection of moving objects.
FILED Monday, April 23, 2018
APPL NO 15/960298
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0063 (20130101)
G06K 9/3216 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 3/0093 (20130101)
G06T 7/33 (20170101)
G06T 7/254 (20170101)
G06T 2207/10032 (20130101)
G06T 2207/30181 (20130101)
G06T 2207/30212 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 10302816 Deierling et al.
FUNDED BY
National Science Foundation (NSF)
National Center for Atmospheric Research (NCAR)
Federally Funded Research and Development Center (FFRDC)
Operated by University Corporation for Atmospheric Research (UCAR) at Boulder, CO
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) University Corporation for Atmospheric Research (Boulder, Colorado)
ASSIGNEE(S) University Corporation for Atmiospheric Research (Boulder, Colorado)
INVENTOR(S) Wiebke Kristina Deierling (Boulder, Colorado);  Kyoko Ikeda (Longmont, Colorado);  Matthias Steiner (Boulder, Colorado)
ABSTRACT A method and system for determining and displaying lightning potential information is provided. The method includes receiving a radar data and temperature data for a grid location. If the radar data is above a radar threshold and the temperature data is below a temperature threshold a predictor field is computed. One or more predictor fields may be used to determine a lightning potential. Fuzzy logic may be used to combine predictor fields into a lightning potential. A grid of lightning potential values may be used to determine the lightning potential at a target location, or to indicate the lightning potential in a region outside an inner outlook region including the target location. A display may include an icon with an inner and outer portion displaying lightning potential in an inner and outer outlook region. A display may further include future lightning potential information.
FILED Wednesday, August 27, 2014
APPL NO 14/470205
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Meteorology
G01W 1/02 (20130101) Original (OR) Class
G01W 1/10 (20130101)
G01W 1/16 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 21/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305176 Bridgelall et al.
FUNDED BY
Department of Transportation (USDOT)
APPLICANT(S) University of North Dakota (Grand Forks, North Dakota);  NDSU Research Foundation (Fargo, North Dakota)
ASSIGNEE(S) University of North Dakota (Grand Forks, North Dakota);  NDSU Research Foundation (Fargo, North Dakota)
INVENTOR(S) Raj Bridgelall (Planno, Texas);  Michael Corcoran (Grand Forks, North Dakota)
ABSTRACT A vehicle includes a body providing structural support and defining a fuselage perimeter and including a plurality of bands, a plurality of antennas integrated into the plurality of bands, and a transceiver operatively connected to each of the plurality of antennas. The transceiver is configured to power selected sub-sets of the plurality of antennas to generate a directional antenna beam.
FILED Tuesday, May 19, 2015
APPL NO 14/716288
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 1/36 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 43/00 (20130101)

Antennas, i.e Radio Aerials
H01Q 1/27 (20130101)
H01Q 1/286 (20130101) Original (OR) Class
H01Q 3/26 (20130101)

Transmission
H04B 7/0617 (20130101)
H04B 7/18504 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Education (ED) 

US 10299972 Kuiken et al.
FUNDED BY
Department of Education (ED)
Office of Special Education and Rehabilitative Services (OSERS)
National Institute on Disability and Rehabilitation Research (NIDRR)
APPLICANT(S) REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois)
ASSIGNEE(S) Rehabilitation Institute Of Chicago (Chicago, Illinois)
INVENTOR(S) Todd A. Kuiken (Oak Park, Illinois);  James Lipsey (Oak Park, Illinois);  Frank J. Ursetta (Chicago, Illinois)
ABSTRACT A drive mechanism for a wheelchair may include a hand grip having a continuous track that moves over a drive rotator. The hand grip may have a flat, top surface that extends ventrally from the wheelchair. The drive mechanism may include a drivetrain connected to the drive rotator, such that movement of the hand grip in a dorsal or a ventral direction causes the drive rotator to rotate, and such rotation actuates the drivetrain. The drive mechanism may further comprise a switch. When the switch is in a first position, actuation of the drivetrain drives the wheels of the wheelchair. When the switch is in a second position, actuation of the drivetrain drives a mechanism that lifts the wheelchair into a standing position.
FILED Tuesday, March 07, 2017
APPL NO 15/451973
ART UNIT 3611 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices
A61G 5/14 (20130101)
A61G 5/021 (20130101) Original (OR) Class
A61G 5/022 (20130101)
A61G 5/023 (20130101)
A61G 5/026 (20130101)
A61G 5/0825 (20161101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 10300151 Zheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
U.S. State Government
State of Texas
Cancer Prevention and Research Institute of Texas (TX-CPRIT)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Jie Zheng (Allen, Texas);  Mengxiao Yu (Plano, Texas)
ABSTRACT Methods and systems for evaluating renal function of a live subject. The method includes intravenously administering nanoparticles of a noble metal to the kidney of the live subject, followed by illuminating the kidney with a near infrared excitation wavelength such that the nanoparticles in the kidney fluoresce, and finally detecting presence or absence of nanoparticle fluorescence in the kidney. Detecting presence or absence of nanoparticle fluorescence includes obtaining at least one image of the kidney through the subject's skin.
FILED Monday, September 12, 2016
APPL NO 15/262307
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0071 (20130101)
A61B 5/4222 (20130101)
A61B 5/7275 (20130101)
A61B 2503/40 (20130101)
A61B 2503/42 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0004 (20130101)
A61K 49/0056 (20130101)
A61K 49/0065 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 10301359 Sasisekharan et al.
FUNDED BY
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Ram Sasisekharan (Lexington, Massachusetts);  Kannan Tharakaraman (Arlington, Massachusetts);  Rahul Raman (Waltham, Massachusetts)
ABSTRACT The present invention provides, among other things, technologies and methodologies for detection, treatment, and/or prevention of influenza transmission and/or infection. The present invention also provides technologies for monitoring influenza variants for their potential to present a pandemic risk to humans.
FILED Wednesday, April 30, 2014
APPL NO 14/888205
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/145 (20130101)

Peptides
C07K 14/005 (20130101) Original (OR) Class
C07K 16/1018 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/16122 (20130101)
C12N 2760/16134 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101)
G01N 2333/11 (20130101)
G01N 2469/10 (20130101)
G01N 2469/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10301584 Vunjak-Novakovic et al.
FUNDED BY
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Gordana Vunjak-Novakovic (New York, New York);  Sarindr Bhumiratana (Brooklyn, New York);  Keith Yeager (Jersey City, New Jersey)
ABSTRACT A perfusion bioreactor chamber for engineering a broad spectrum of tissues. The bioreactor allows controlled distribution of fluid through or around scaffolding materials of various shapes, structures and topologies during prolonged periods of cultivation.
FILED Thursday, April 17, 2014
APPL NO 14/782630
ART UNIT 1799 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 21/08 (20130101) Original (OR) Class
C12M 23/40 (20130101)
C12M 25/14 (20130101)
C12M 29/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10305193 Larussi et al.
FUNDED BY
APPLICANT(S) RAYTHEON COMPANY (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Amedeo Larussi (Waltham, Massachusetts);  David A. Buell (Waltham, Massachusetts);  Craig R. Adams (Waltham, Massachusetts);  Christopher Moshenrose (Waltham, Massachusetts)
ABSTRACT A high speed radio frequency signal interconnect device provides for signal communication within a system at cryogenic temperatures. The device includes a plurality of conductive traces provided on a first dielectric substrate where the ends of the traces have a predetermined shape. A second dielectric substrate covers the first dielectric substrate leaving the ends of the traces exposed. A connector is coupled to each respective end and includes pins coupled to a respective trace. Each connector is configured to define a respective isolating chamber about each of the first ends of the conductive traces where the pins are attached.
FILED Thursday, February 22, 2018
APPL NO 15/902396
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/66 (20130101)
H01L 2223/6627 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 1/047 (20130101)
H01P 5/028 (20130101)

Antennas, i.e Radio Aerials
H01Q 13/206 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, May 28, 2019.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190528.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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