FedInvent™ Patents
Patent Details for Tuesday, June 11, 2019
This page was updated on Monday, March 27, 2023 at 05:49 AM GMT
Department of Health and Human Services (HHS)
| US 10314302 | Hubel et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Allison Hubel (St. Paul, Minnesota); Kathryn Lindsay Pollock (Seattle, Washington) |
| ABSTRACT | This disclosure describes a cryopreservative composition and methods for storing cells. Generally, the cryopreservative composition includes a sugar component and a sugar alcohol component, and is effective for storing and recovering cells without requiring dimethyl sulfoxide (DMSO). |
| FILED | Friday, December 16, 2016 |
| APPL NO | 15/381530 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Original (OR) Class A01N 1/0284 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314473 | Smith |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | R. Theodore Smith (New York, New York) |
| ABSTRACT | A system and method for in vivo detection and quantification of drusen present in the retina via administering an excitation signal to the retina of the eye and detecting an electromagnetic emissions spectrum from the retina in response to the excitation signal. The electromagnetic emissions spectrum may be used to identify a plurality of component emissions spectra, each component emissions spectrum corresponding to fluorescence from a component of the retina, one of the component emissions spectra corresponding to a target emissions spectrum. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/261102 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) A61B 3/0025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314491 | Cui et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Dongyao Cui (Boston, Massachusetts); Kengyeh K. Chu (Boston, Massachusetts); Guillermo J. Tearney (Boston, Massachusetts) |
| ABSTRACT | Optics for apodizing an optical imaging probe beam, and methods for fabricating optics for apodizing an optical imaging probe beam are provided. In some embodiments, optics for apodizing an electrical comprises: an optical fiber; a focusing element coaxially aligned with the optical fiber; an element having a cylindrical bore and an angled reflective surface, wherein a first portion of a beam focused by the focusing element enters the cylindrical bore and a second portion of the beam is reflected at an angle to produce a beam with a generally annular-shaped profile. |
| FILED | Monday, February 12, 2018 |
| APPL NO | 15/894574 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/051 (20130101) A61B 1/00112 (20130101) A61B 1/00131 (20130101) A61B 1/00147 (20130101) A61B 5/0066 (20130101) Original (OR) Class A61B 5/0084 (20130101) A61B 5/0086 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02015 (20130101) G01B 9/02091 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2021/015 (20130101) Optical Elements, Systems, or Apparatus G02B 6/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314503 | Prerau et al. |
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| FUNDED BY |
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| APPLICANT(S) | Michael J. Prerau (Somerville, Massachusetts); Patrick L. Purdon (Somerville, Massachusetts); Uri Eden (Somerville, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Michael J. Prerau (Somerville, Massachusetts); Patrick L. Purdon (Somerville, Massachusetts); Uri Eden (Somerville, Massachusetts) |
| ABSTRACT | Systems and methods for tracking dynamic structure in physiological data are provided. In some aspects, the method includes providing physiological data, including electroencephalogram (“EEG”) data, acquired from a subject and assembling a time-frequency representation of signals from the physiological data. The method also includes generating a dynamic model of at least one non-stationary spectral feature, such as at least one non-stationary spectral peak, using the time-frequency representation and a user indication, and applying a dynamic model of at least one non-stationary spectral feature in a parameter estimation algorithm to compute concurrent estimates of spectral parameters describing the at least one non-stationary spectral feature. The method also includes tracking the spectral parameters of the at least one spectral feature over time. |
| FILED | Friday, June 27, 2014 |
| APPL NO | 14/900805 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/048 (20130101) A61B 5/0402 (20130101) A61B 5/0488 (20130101) A61B 5/0496 (20130101) A61B 5/0533 (20130101) A61B 5/725 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/4806 (20130101) A61B 5/4821 (20130101) A61B 5/4839 (20130101) A61B 5/7253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314574 | Linderman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Stephen W. Linderman (St. Louis, Missouri); Guy M. Genin (St. Louis, Missouri); Stavros Thomopoulos (St. Louis, Missouri) |
| ABSTRACT | The field of the disclosure relates generally to sutures and, more specifically, to enhancing suture repair mechanics using adhesives. |
| FILED | Friday, November 13, 2015 |
| APPL NO | 14/940541 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1146 (20130101) A61B 17/06166 (20130101) Original (OR) Class A61B 2017/00884 (20130101) A61B 2017/00951 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314683 | Martin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Tepha, Inc. (Lexington, Massachusetts) |
| ASSIGNEE(S) | Tepha, Inc. (Lexington, Massachusetts) |
| INVENTOR(S) | David P. Martin (Arlington, Massachusetts); Said Rizk (Windham, New Hampshire); Ajay Ahuja (Long Grove, Illinois); Simon F. Williams (Sherborn, Massachusetts) |
| ABSTRACT | Absorbable polyester fibers, braids, and surgical meshes with prolonged strength retention have been developed. These devices are preferably derived from biocompatible copolymers or homopolymers of 4-hydroxybutyrate. These devices provide a wider range of in vivo strength retention properties than are currently available, and could offer additional benefits such as anti-adhesion properties, reduced risks of infection or other post-operative problems resulting from absorption and eventual elimination of the device, and competitive cost. The devices may also be particularly suitable for use in pediatric populations where their absorption should not hinder growth, and provide in all patient populations wound healing with long-term mechanical stability. The devices may additionally be combined with autologous, allogenic and/or xenogenic tissues to provide implants with improved mechanical, biological and handling properties. |
| FILED | Thursday, July 21, 2016 |
| APPL NO | 15/215878 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0063 (20130101) Original (OR) Class A61F 2002/0068 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/48 (20130101) A61L 31/06 (20130101) A61L 31/06 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0004 (20130101) B29C 47/0014 (20130101) B29C 71/0072 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 67/04 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/16 (20130101) D01D 5/088 (20130101) D01D 5/098 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/62 (20130101) D01F 6/84 (20130101) D01F 6/625 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/1362 (20150115) Y10T 428/1369 (20150115) Y10T 428/249922 (20150401) Y10T 442/10 (20150401) Y10T 442/183 (20150401) Y10T 442/184 (20150401) Y10T 442/2525 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314802 | Stock et al. |
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| FUNDED BY |
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| APPLICANT(S) | Signum Biosciences, Inc. (Monmouth Junction, New Jersey) |
| ASSIGNEE(S) | Signum Biosciences, Inc. (Monmouth Junction, New Jersey) |
| INVENTOR(S) | Jeffry B. Stock (Princeton, New Jersey); Maxwell Stock (Boulder, Colorado); Keshava Rapole (Edison, New Jersey); Seung-Yub Lee (Princeton, New Jersey); Michael Voronkov (Pennington, New Jersey); Eduardo Perez (Somerset, New Jersey); Joel Gordon (Prinecton Junction, New Jersey); Shuyi Chen (Somerset, New Jersey); Jinglong Chen (Newark, New Jersey) |
| ABSTRACT | Among other things, the present invention provides novel isoprenyl compounds capable of effectively modulating inflammatory responses and pharmaceutical, cosmetic, cosmeceutical and topical compositions comprising these isoprenyl compounds. Anti-inflammatory compounds of the present invention are useful in treating or preventing diseases or conditions associated with inflammation. Proinflammatory compounds of the present invention are useful in treating or preventing diseases or conditions associated with suppression of inflammatory responses. Thus, the present invention also provides methods useful in the treatment or prevention of diseases or conditions associated with inflammation as well as methods useful in the treatment or prevention of diseases or conditions associated with suppression of inflammatory responses. |
| FILED | Tuesday, August 01, 2017 |
| APPL NO | 15/665922 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/197 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 243/34 (20130101) C07C 321/18 (20130101) C07C 323/59 (20130101) C07C 335/08 (20130101) C07C 2601/02 (20170501) C07C 2601/14 (20170501) Heterocyclic Compounds C07D 207/16 (20130101) C07D 209/18 (20130101) C07D 209/48 (20130101) C07D 217/26 (20130101) C07D 243/34 (20130101) C07D 295/145 (20130101) C07D 307/54 (20130101) C07D 333/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314810 | Sherr et al. |
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| FUNDED BY |
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| APPLICANT(S) | David H. Sherr (West Roxbury, Massachusetts); Michael Pollastri (Waltham, Massachusetts); Jennifer Schlezinger (East Falmouth, Massachusetts); Sarah Haigh Molina (Boston, Massachusetts); Scott Schaus (Boston, Massachusetts); Joshua Robert Giguere (Sharon, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts); Northeastern University (Boston, Massachusetts); Boston Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | David H. Sherr (West Roxbury, Massachusetts); Michael Pollastri (Waltham, Massachusetts); Jennifer Schlezinger (East Falmouth, Massachusetts); Sarah Haigh Molina (Boston, Massachusetts); Scott Schaus (Boston, Massachusetts); Joshua Robert Giguere (Sharon, Massachusetts) |
| ABSTRACT | Provided herein are novel agents that modulate AhR activity for use in therapeutic compositions and methods thereof for inhibiting cancer cell proliferation and tumor cell invasion and metastasis. The agents comprise AhR inhibitors or non-constitutive AhR agonists of Formula (I) and (II) for the inhibition of cancer cell growth and parameters that characterize tumor metastasis, such as tumor cell invasiveness. |
| FILED | Wednesday, July 27, 2011 |
| APPL NO | 13/812375 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/35 (20130101) A61K 31/35 (20130101) A61K 31/35 (20130101) A61K 31/352 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 311/22 (20130101) C07D 407/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314816 | Weibel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Douglas Benjamin Weibel (Madison, Wisconsin); Ye Jin Eun (Cambridge, Massachusetts); Marie Hazel Foss (Hillsboro, Oregon); Katherine Ann Hurley (Madison, Wisconsin) |
| ABSTRACT | Described herein are antimicrobial compounds identified via a high-throughput inhibitor screen of the in vitro activity of MipZ, which is an ATPase that regulates division site placement in Caulobacter crescentus. The compounds and their analogs are active against bacterial membranes and thus represent a novel class of antimicrobial compounds. The antimicrobial compounds are effective against both actively growing bacterial cells as well as bacterial cells in the stationary phase. The antimicrobial compounds are also effective against bacteria in biofilms. |
| FILED | Monday, June 10, 2013 |
| APPL NO | 13/913912 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/403 (20130101) Original (OR) Class A61K 31/4045 (20130101) Heterocyclic Compounds C07D 209/04 (20130101) C07D 209/44 (20130101) C07D 209/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314818 | Fenical et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | William Fenical (Del Mar, California); Paul Jensen (San Diego, California); Tracy Mincer (San Diego, California); Robert H. R. Feling (Wiesbaden, Germany) |
| ABSTRACT | The present invention is based on the discovery that certain fermentation products of the marine actinomycete strains CNB392 and CNB476 are effective inhibitors of hyperproliferative mammalian cells. The CNB392 and CNB476 strains lie within the family Micromonosporaceae, and the generic epithet Salinospora has been proposed for this obligate marine group. The reaction products produced by this strain are classified as salinosporamides, and are particularly advantageous in treating neoplastic disorders due to their low molecular weight, low IC50 values, high pharmaceutical potency, and selectivity for cancer cells over fungi. |
| FILED | Thursday, July 20, 2017 |
| APPL NO | 15/655739 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/397 (20130101) A61K 31/407 (20130101) Original (OR) Class A61K 31/424 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 491/04 (20130101) C07D 491/044 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/18 (20130101) C12P 17/188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314824 | Pavliv et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cumberland Pharmaceuticals Inc. (Nashville, Tennessee); Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Cumberland Pharmaceuticals Inc. (Nashville, Tennessee); Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Leo Pavliv (Cary, North Carolina); Bryan Voss (Nashville, Tennessee); James West (Nashville, Tennessee); Erica Carrier (Nashville, Tennessee) |
| ABSTRACT | The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by administration of a therapeutically effective amount of ifetroban, or a pharmaceutically acceptable salt thereof. |
| FILED | Monday, June 11, 2018 |
| APPL NO | 16/004666 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/00 (20130101) A61K 9/0019 (20130101) A61K 9/2059 (20130101) A61K 9/4858 (20130101) A61K 31/421 (20130101) Original (OR) Class A61K 31/422 (20130101) Heterocyclic Compounds C07D 263/30 (20130101) C07D 407/04 (20130101) C07D 413/04 (20130101) C07D 493/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314826 | Sarkar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rajabrata Sarkar (Ellicott City, Maryland); Mark Hoofnagle (Baltimore, Maryland); Subhradip Mukhopadhyay (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Rajabrata Sarkar (Ellicott City, Maryland); Mark Hoofnagle (Baltimore, Maryland); Subhradip Mukhopadhyay (Baltimore, Maryland) |
| ABSTRACT | It has now been discovered that p53 is a potent inhibitor of angiogenesis and arteriogenesis. Inhibition of p53 stimulates angiogenesis, arteriogenesis and improves perfusion in limbs. Therefore, methods are provided for treating diabetic-induced ischemia in a subject in need thereof comprising locally administering a therapeutically effective amount of one or more p53 molecule inhibitors or analogs and derivatives thereof to a site of ischemic tissue in the subject. Methods are provided for improving limb perfusion in a subject in need thereof comprising locally administering a therapeutically effective amount one or more p53 inhibitors together with a therapeutic agent or separately from the therapeutic agent to cells of a limb of a subject in need thereof. Methods are also provided for improving ischemia-induced angiogenesis and arteriogenesis in method of improving ischemia-induced angiogenesis in tissue of a limb comprising administering a therapeutically effective amount one or more p53 inhibitors individually or in combination with another therapeutic to a subject in need thereof. |
| FILED | Monday, February 09, 2015 |
| APPL NO | 14/617149 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/428 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314827 | Castro et al. |
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| FUNDED BY |
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| APPLICANT(S) | Infinity Pharmaceuticals, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Infinity Pharmaceuticals, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Alfredo C. Castro (Winchester, Massachusetts); Michael J. Grogan (Winchester, Massachusetts); Karen J. McGovern (Groton, Massachusetts); Martin R. Tremblay (Melrose, Massachusetts) |
| ABSTRACT | The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula: |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/047008 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/17 (20130101) A61K 31/56 (20130101) A61K 31/58 (20130101) A61K 31/69 (20130101) A61K 31/196 (20130101) A61K 31/198 (20130101) A61K 31/454 (20130101) A61K 31/519 (20130101) A61K 31/573 (20130101) A61K 31/664 (20130101) A61K 31/704 (20130101) A61K 31/4355 (20130101) Original (OR) Class A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 31/7076 (20130101) A61K 38/21 (20130101) A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Heterocyclic Compounds C07D 307/94 (20130101) C07D 471/04 (20130101) C07D 471/10 (20130101) C07D 491/04 (20130101) C07D 491/10 (20130101) C07D 491/048 (20130101) C07D 491/107 (20130101) Steroids C07J 69/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314835 | Ressler et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Kerry J. Ressler (Atlanta, Georgia); Raul Andero Gali (Barcelona, Spain) |
| ABSTRACT | This disclosure relates to managing conditioned fear and conditions induced by experiencing or witnessing an extreme traumatic event using neurokinin receptor antagonists. In certain embodiments, the disclosure relates to methods of treating or preventing conditioned fear comprising administering an effective about neurokinin 3 receptor antagonist to a subject in need thereof. In certain embodiments, the subject is diagnosed with Post-Traumatic Stress Disorder. In certain embodiments, the neurokinin 3 receptor antagonist is (R)—N-{{3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-methylacetamine or salts thereof. |
| FILED | Thursday, June 25, 2015 |
| APPL NO | 15/320952 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4545 (20130101) Original (OR) Class A61K 31/4545 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314839 | Jenkins |
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| FUNDED BY |
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| APPLICANT(S) | Elysium Therapeutics, Inc. (Danville, California) |
| ASSIGNEE(S) | Elysium Therapeutics, Inc. (Danville, California) |
| INVENTOR(S) | Thomas E. Jenkins (Half Moon Bay, California) |
| ABSTRACT | The present invention provides a composition comprising an opioid agonist, and a polymer-antagonist conjugate. The polymer-antagonist conjugate preferably does not hydrolyze upon administration to a patient, and does not bind to the opioid receptors. The covalent bond between the polymer and the antagonist in the conjugate is broken over a defined period of time to release the antagonist into the formulation. The released antagonist attenuates the liking of the agonist, thereby eliminating the incentive to the diversion of the medicines. |
| FILED | Tuesday, October 20, 2015 |
| APPL NO | 14/918464 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/4866 (20130101) A61K 31/485 (20130101) Original (OR) Class A61K 31/485 (20130101) A61K 45/06 (20130101) A61K 47/55 (20170801) A61K 47/60 (20170801) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314854 | Salem et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Aliasger K. Salem (Coralville, Iowa); Amani Makkouk (Iowa City, Iowa); Vijaya B. Joshi (Minneapolis, Minnesota); George Weiner (Iowa City, Iowa) |
| ABSTRACT | Disclosed are compositions, kits, and methods for treating cancer in a subject in need thereof. The compositions, kits, and methods may be used to treat a tumor in a subject in situ. The compositions, kits, and methods comprise or utilize cytotoxic particles, immune checkpoint inhibitors, and/or T-cell stimulatory agents. |
| FILED | Monday, May 16, 2016 |
| APPL NO | 15/572347 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1647 (20130101) A61K 31/704 (20130101) Original (OR) Class A61K 31/7088 (20130101) A61K 39/0011 (20130101) A61K 39/39 (20130101) A61K 39/3955 (20130101) A61K 47/34 (20130101) A61K 2039/54 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2039/585 (20130101) A61K 2039/55561 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/2878 (20130101) C07K 2317/75 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314855 | Pavel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Ana Brandusa Pavel (New York, New York); Joshua David Campbell (Sharon, Massachusetts); Marc Elliott Lenburg (Brookline, Massachusetts); Avrum Spira (Newton, Massachusetts) |
| ABSTRACT | The methods and assays described herein relate to detection, diagnosis, and treatment of lung cancer, e.g., by detecting the level of expression of certain miRNAs described herein and/or by therapeutically increasing the level of those miRNAs. |
| FILED | Tuesday, January 23, 2018 |
| APPL NO | 15/877447 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 2539/10 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314870 | Fisher et al. |
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| FUNDED BY |
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| APPLICANT(S) | Virginia Commonwealth University (Richmond, Virginia) |
| ASSIGNEE(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| INVENTOR(S) | Paul Fisher (Richmond, Virginia); Devanand Sarkar (Richmond, Virginia); Paul Dent (Richmond, Virginia) |
| ABSTRACT | A tropism modified cancer terminator virus (Ad.5/3-CTV; Ad.5/3-CTV-M7) has been found to have infectivity that is Coxsackie Adenoviral Receptor (CAR) independent. The Ad.5/3-CTV (Ad.5/3-CTV-M7) may be used alone or in combination with other therapeutic agents such as agents that augment reactive oxygen (ROS) production, HDAC inhibitors, MCL-1 inhibitors and Bcl-2 inhibitors to treat a variety of cancers particularly including malignant glioma (GBM), renal cancer, prostate cancer, and colorectal cancer. |
| FILED | Tuesday, December 10, 2013 |
| APPL NO | 14/650775 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/166 (20130101) A61K 31/404 (20130101) A61K 35/768 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 45/06 (20130101) A61K 2039/5254 (20130101) A61K 2039/55511 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2710/10032 (20130101) C12N 2710/10321 (20130101) C12N 2710/10332 (20130101) C12N 2710/10343 (20130101) C12N 2710/10371 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314883 | Isakson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Brant E. Isakson (Charlottesville, Virginia); Marie Billaud (Mount Washington, Pennsylvania); Leon J. DeLalio (Wading River, New York); Thu Le (Charlottesville, Virginia) |
| ABSTRACT | Both purinergic signaling through nucleotides such as ATP and noradrenergic signaling through molecules such as norepinephrine regulate vascular tone and blood pressure. Pannexin1 (Panx1), which forms large-pore, ATP-releasing channels, is present in vascular smooth muscle cells in peripheral blood vessels and participates in noradrenergic responses. Using pharmacological approaches and mice conditionally lacking Panx1 in smooth muscle cells, we found that Panx1 contributed to vasoconstriction mediated by the α1 adrenoreceptor (α1AR), whereas vasoconstriction in response to serotonin or endothelin-1 was independent of Panx1. Analysis of the Panx1-deficient mice showed that Panx1 contributed to blood pressure regulation especially during the night cycle when sympathetic nervous activity is highest. Using mimetic peptides and site-directed mutagenesis, we identified a specific amino acid sequence in the Panx1 intracellular loop that is essential for activation by α1AR signaling. Collectively, these data describe a specific link between noradrenergic and purinergic signaling in blood pressure homeostasis. |
| FILED | Friday, February 12, 2016 |
| APPL NO | 15/549232 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/08 (20130101) Original (OR) Class A61K 38/10 (20130101) A61K 38/2013 (20130101) Peptides C07K 7/06 (20130101) C07K 14/163 (20130101) C07K 14/705 (20130101) C07K 2319/00 (20130101) C07K 2319/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314889 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Reen Wu (Davis, California); Ching-Hsien Chen (Davis, California); Chen-Chen Lee (Davis, California) |
| ABSTRACT | This disclosure relates to compositions of isolated polypeptides and methods of their use for the treatment and prevention of disease or disease symptoms associated with MARCKS phosphorylation and/or dissociation from the cell membrane, including but not limited to allergic inflammation, asthma, chronic bronchitis, COPD, infection, hyper-reactivity, cystic fibrosis, ulcerative colitis, Crohn's disease, irritable bowel syndrome, rosacea, eczema, psoriasis, acne, arthritis, rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus. |
| FILED | Friday, December 19, 2014 |
| APPL NO | 15/106263 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/007 (20130101) A61K 38/10 (20130101) A61K 38/177 (20130101) Original (OR) Class A61K 38/1709 (20130101) Peptides C07K 7/08 (20130101) C07K 14/4703 (20130101) C07K 16/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314893 | Daniell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); University of Florida Research Foundation, Inc. (Gainsville, Florida) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Henry Daniell (Media, Pennsylvania); Qiuhong Li (Gainsville, Florida); Mohan K. Raizada (Alachua, Florida) |
| ABSTRACT | Emerging evidence indicates that diminished activity of the vasoprotective axis of the renin-angiotensin system, constituting angiotensin converting enzyme2 (ACE2) and its enzymatic product, angiotensin-(1-7) [Ang-(1-7)] contribute to pulmonary hypertension (PH). However, clinical success for long-term delivery of ACE2 or Ang-(1-7) would require stability and ease of administration to increase patient compliance. Chloroplast expression of therapeutic proteins enables their bioencapsulation within plant cells to protect from acids and gastric enzymes; fusion to a transmucosal carrier facilitates effective systemic absorption. Oral feeding of rats with bioencapsulated ACE2 or Ang-(1-7) attenuated monocrotaline (MCT)-induced increase in right ventricular systolic pressure, decreased pulmonary vessel wall thickness and improved right heart function in both prevention and reversal protocols. Furthermore, combination of ACE2 and Ang-(1-7) augmented the beneficial effects against cardio-pulmonary pathophysiology induced by MCT administration. Experiments have also been performed which indicate that this approach is also suitable for the treatment or inhibition of experimental uveitis and autoimmune uveoretinitis These studies provide proof-of-concept for a novel low-cost oral ACE2 or Ang-(1-7) delivery system using transplastomic technology for pulmonary and ocular disease therapeutics. |
| FILED | Monday, April 18, 2016 |
| APPL NO | 15/030377 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/0053 (20130101) A61K 9/1664 (20130101) A61K 9/5063 (20130101) A61K 36/23 (20130101) A61K 36/28 (20130101) A61K 36/31 (20130101) A61K 38/22 (20130101) A61K 38/164 (20130101) A61K 38/4813 (20130101) Original (OR) Class A61K 47/65 (20170801) A61K 47/6415 (20170801) Peptides C07K 14/28 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) C12N 15/8214 (20130101) C12N 15/8257 (20130101) Enzymes C12Y 304/15001 (20130101) C12Y 304/17023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314894 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| INVENTOR(S) | Qingyu Wu (Orange Village, Ohio); Shenghan Chen (Beachwood, Ohio) |
| ABSTRACT | A method of treating a cardio-renal disease is described that includes administering to a subject in need thereof a therapeutically effective amount of proprotein convertase subtilisin/kexin-6 (PCSK6), or an effective fragment thereof, which functions as a corin activator. |
| FILED | Thursday, February 12, 2015 |
| APPL NO | 14/620278 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/482 (20130101) Original (OR) Class Enzymes C12Y 304/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314900 | Valenzuela et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); Fundaçao Oswaldo Cruz (FIOCRUZ) (Rio de Janeiro, Brazil) |
| ASSIGNEE(S) | The United States of America, as represted by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Fundaçao Oswaldo Cruz (FIOCRUZ) (Rio de Janeiro, Brazil) |
| INVENTOR(S) | Jesus G. Valenzuela (Gaithersburg, Maryland); Jose M. C. Ribeiro (Rockville, Maryland); Aldina Barral (Bahia, Brazil); Manoel Barral Netto (Bahia, Brazil); Claudia I. Brodskyn (Bahia, Brazil); Regis Gomes (Bahia, Brazil) |
| ABSTRACT | Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed. |
| FILED | Tuesday, January 09, 2018 |
| APPL NO | 15/866050 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0003 (20130101) A61K 39/008 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/57 (20130101) A61K 2039/58 (20130101) A61K 2039/575 (20130101) Peptides C07K 14/44 (20130101) C07K 14/43577 (20130101) C07K 16/18 (20130101) C07K 16/20 (20130101) C07K 2317/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) Technologies for Adaptation to Climate Change Y02A 50/41 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314901 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GenVec, Inc. (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GenVec, Inc. (Gaitherburg, Maryland) |
| INVENTOR(S) | Ping Chen (Potomac, Maryland); Duncan McVey (Derwood, Maryland); Douglas E. Brough (Gaithersburg, Maryland); Joseph Bruder (Gaithersburg, Maryland) |
| ABSTRACT | The invention is directed to a composition comprising one or more polypeptides or one or more nucleic acid sequences that can induce a protective immune response against Plasmodium species that infect humans. The invention also is directed to a method of using such compositions to induce a protective immune response against a Plasmodium parasite in a mammal. |
| FILED | Thursday, June 14, 2018 |
| APPL NO | 16/008852 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/015 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/5256 (20130101) Technologies for Adaptation to Climate Change Y02A 50/412 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314908 | Sitkovsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of (Washington, District of Columbia) |
| INVENTOR(S) | Michail V. Sitkovsky (Boston, Massachusetts); Akio Ohta (Newton, Massachusetts) |
| ABSTRACT | A method is provided herein to increase an immune response to an antigen. The method includes administering an agent that inhibits extracellular adenosine or inhibits adenosine receptors. Also disclosed are methods to increase the efficacy of a vaccine and to increase an immune response to a tumor antigen or immune cell-mediated tumor destruction. |
| FILED | Monday, August 15, 2016 |
| APPL NO | 15/237316 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/52 (20130101) A61K 31/53 (20130101) A61K 31/365 (20130101) A61K 31/519 (20130101) A61K 31/522 (20130101) A61K 31/7088 (20130101) A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/55561 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5055 (20130101) G01N 2333/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314924 | Sandberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS EYE and EAR INFIRMARY (Boston, Massachusetts); UCL BUSINESS PLC (London, United Kingdom); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts); UCL Business PLC (London, United Kingdom); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Michael A. Sandberg (Reading, Massachusetts); Basil Pawlyk (Hampton Falls, New Hampshire); Alan Finlay Wright (Edinburgh, United Kingdom); Xinhua Shu (Glasgow, United Kingdom); Tiansen Li (Clarksburg, Maryland); Robin Ali (London, United Kingdom) |
| ABSTRACT | Methods for treating a human subject who has X-linked Retinitis Pigmentosa (XLRP) or another clinically-defined ophthalmological condition due to a loss-of-function mutation in the gene encoding the retinitis pigmentosa GTPase regulator (RPGR) protein, the method comprising administering to the subject a nucleic acid comprising an adeno-associated viral vector comprising an abbreviated human RPGR cDNA. |
| FILED | Friday, July 17, 2015 |
| APPL NO | 15/328617 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 48/005 (20130101) Original (OR) Class Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314938 | Kaplan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Ballou Hall, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Ung-Jin Kim (Daejeon, South Korea); Jaehyung Park (Decatur, Georgia); Hyoung-Joon Jin (Seoul, South Korea) |
| ABSTRACT | The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels. |
| FILED | Thursday, February 16, 2017 |
| APPL NO | 15/434484 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/38 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 27/3604 (20130101) A61L 2430/02 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/003 (20130101) B29C 39/203 (20130101) B29C 55/005 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 7/01 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2089/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2007/00 (20130101) B29L 2009/00 (20130101) Peptides C07K 14/43536 (20130101) C07K 14/43586 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/07 (20130101) C08J 3/075 (20130101) C08J 5/18 (20130101) C08J 9/26 (20130101) C08J 9/28 (20130101) C08J 9/0061 (20130101) C08J 2201/0444 (20130101) C08J 2201/0504 (20130101) C08J 2205/022 (20130101) C08J 2389/00 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249921 (20150401) Y10T 442/10 (20150401) Y10T 442/60 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314940 | Voytik-Harbin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation Office of Technology Commercialization (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Sherry Voytik-Harbin (Zionsville, Indiana) |
| ABSTRACT | A collagen-based therapeutic delivery device includes an insoluble synthetic collagen-fibril matrix comprising a polymerization product of soluble oligomeric collagen or a polymerization product of a mixture of soluble oligomeric collagen with one or more type of non-oligomeric soluble collagen molecules, such as, for example, soluble telocollagen and/or soluble atelocollagen, and an active agent dispersed throughout the collagen-fibril matrix or within a portion of the collagen-fibril matrix. A pre-matrix composition includes an aqueous solution including soluble collagen-fibril building blocks and an active agent in the aqueous solution. The soluble collagen-fibril building blocks include soluble oligomeric collagen or a mixture of soluble oligomeric collagen with non-oligomeric soluble collagen molecules. The building blocks are operable to self-assemble into a macromolecular synthetic collagen-fibril matrix in the absence of an exogenous cross-linking agent. Methods of making and using the pre-matrix composition and the device are also provided. |
| FILED | Thursday, August 27, 2015 |
| APPL NO | 15/505046 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/0024 (20130101) A61K 38/18 (20130101) A61K 47/42 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 2300/414 (20130101) A61L 2300/604 (20130101) A61L 2400/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10315029 | Tai |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Changfeng Tai (Wexford, Pennsylvania) |
| ABSTRACT | Provided herein are methods and devices useful for inhibiting or treating urological conditions, such as overactive bladder (OAB) symptoms including bladder overactivity, urinary frequency, urinary urgency, urinary incontinence, interstitial cystitis (IC), urinary retention, and pelvic pain; gastrointestinal conditions, such as fecal incontinence, irritable bowel syndrome (IBS), and constipation; and sexual conditions, such as premature ejaculation, erectile disorder, and female sexual arousal disorder by non-invasive transcutaneous electrical stimulation of the foot. |
| FILED | Wednesday, December 20, 2017 |
| APPL NO | 15/848143 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36007 (20130101) Original (OR) Class A61N 1/36014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10315046 | Stoianovici et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dan Stoianovici (Baltimore, Maryland); Alexandru Patriciu (Ancaster, Canada); Dumitru Mazilu (Lutherville, Maryland); Doru Petrisor (Towson, Maryland); Louis R. Kavoussi (Lutherville, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Dan Stoianovici (Baltimore, Maryland); Alexandru Patriciu (Ancaster, Canada); Dumitru Mazilu (Lutherville, Maryland); Doru Petrisor (Towson, Maryland); Louis R. Kavoussi (Lutherville, Maryland) |
| ABSTRACT | Featured is a robot and a needle delivery apparatus. Such a robot comprises a plurality of actuators coupled to control locating any of number of intervention specific medical devices such as intervention specific needle injectors. Such a robot is usable with image guided interventions using any of a number of types of medical imaging devices or apparatuses including MRI. The end-effector can include an automated low needle delivery apparatus that is configured for dose radiation seed brachytherapy injection. Also featured is an automated seed magazine for delivering seeds to such an needle delivery apparatus adapted for brachytherapy seed injection. |
| FILED | Monday, December 04, 2006 |
| APPL NO | 12/085972 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/0233 (20130101) A61B 17/3468 (20130101) A61B 34/30 (20160201) A61B 2017/00544 (20130101) A61B 2034/304 (20160201) A61B 2090/062 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1007 (20130101) Original (OR) Class A61N 2005/101 (20130101) A61N 2005/1011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10315246 | Wegst et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire); WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Ulrike G. K. Wegst (Hanover, New Hampshire); Philipp Hunger (Pittsburgh, Pennsylvania); Todd Allen (Idaho Falls, Idaho) |
| ABSTRACT | A multiphase composite, formed by freeze-casting, lyophilization, and sintering, has sintered particles forming a scaffold having at least one region of aligned porosity; and a second phase formed in pores of the scaffold. In a particular embodiment, the second phase is a nuclear fuel, in another, the first phase is a nuclear fuel, and in others, both phases are nuclear fuels. In some embodiments, the first phase is a ceramic, and in other embodiments a metal such as stainless steel. In other embodiments, the second phase is a metal, and in other embodiments a ceramic. In some embodiments the second phase is positioned in a subset of pores of the scaffold, at least some additional pores being filled with a third phase. In embodiments, the second phase is also sintered. |
| FILED | Tuesday, March 04, 2014 |
| APPL NO | 14/196883 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 15/00 (20130101) Original (OR) Class B22D 25/005 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/10 (20130101) B22F 3/24 (20130101) B22F 5/10 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 43/025 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/34 (20130101) C01P 2004/50 (20130101) Nuclear Reactors G21C 3/623 (20130101) G21C 3/626 (20130101) G21C 21/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0485 (20130101) H01M 4/661 (20130101) H01M 4/801 (20130101) H01M 2004/021 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316000 | Jaffrey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Samie R. Jaffrey (New York, New York); Jeremy S. Paige (New York, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Samie R. Jaffrey (New York, New York); Jeremy S. Paige (New York, New York) |
| ABSTRACT | The present invention relates to novel fluorophores and their use in combination with novel nucleic acid molecules, called aptamers, that bind specifically to the fluorophore and thereby enhance the fluorescence signal of the fluorophore upon exposure to radiation of suitable wavelength. Molecular complexes formed between the novel fluorophores, novel nucleic acid molecules, and their target molecules are described, and the use of multivalent aptamer constructs as fluorescent sensors for target molecules of interest are also described. |
| FILED | Thursday, February 18, 2010 |
| APPL NO | 13/202250 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0054 (20130101) Heterocyclic Compounds C07D 233/96 (20130101) Original (OR) Class C07D 403/06 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 23/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316031 | Werner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Inhibikase Therapeutics, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Inhibikase Therapeutics, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Milton H. Werner (Marietta, Georgia); Terence A. Kelly (Ridgefield, Connecticut) |
| ABSTRACT | The present invention provides compounds for the prevention or treatment of cancer or a bacterial or viral infection. Additionally, the present invention provides compositions and methods for using these compounds and compositions in the prevention or treatment of cancer or a bacterial or viral infection in a subject. |
| FILED | Wednesday, October 24, 2018 |
| APPL NO | 16/169677 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/14 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/393 (20180101) Y02A 50/467 (20180101) Y02A 50/473 (20180101) Y02A 50/475 (20180101) Y02A 50/481 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316057 | Chae et al. |
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| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Pil Seok Chae (Madison, Wisconsin); Samuel Helmer Gellman (Madison, Wisconsin) |
| ABSTRACT | The invention provides tandem facial amphiphiles for biochemical manipulations and characterization of membrane proteins, such as intrinsic membrane proteins. Members of this new family display favorable behavior with several membrane proteins. These amphiphiles can form relatively small micelles, and small changes in amphiphile chemical structures can result in large changes in their physical properties. The tandem facial amphiphiles can be used to aid the solubilization, isolation, purification, stabilization, crystallization, and/or structural determination of membrane proteins. |
| FILED | Tuesday, July 22, 2014 |
| APPL NO | 14/337496 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) A61B 90/361 (20160201) A61B 2034/301 (20160201) A61B 2090/3782 (20160201) Preparations for Medical, Dental, or Toilet Purposes A61K 9/107 (20130101) A61K 47/26 (20130101) A61K 47/28 (20130101) Steroids C07J 9/00 (20130101) C07J 31/006 (20130101) C07J 41/0061 (20130101) C07J 43/003 (20130101) Original (OR) Class C07J 51/00 (20130101) Peptides C07K 1/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316072 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia); HEALTH RESEARCH, INC. (Buffalo, New York) |
| ASSIGNEE(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia); HEALTH RESEARCH, INC. (Buffalo, New York) |
| INVENTOR(S) | Xiang-Yang Wang (Richmond, Virginia); Xiaofei Yu (Richmond, Virginia); John R. Subjeck (Buffalo, New York) |
| ABSTRACT | A recombinant Flagrp170 protein and pharmaceutical compositions comprising a Flagrp170 protein and related molecules encoding same, and cells presenting such a protein are provided. The Flagrp170 protein comprises an NF-κB-activating domain of Flagellin and an ATP-binding domain truncated Grp170. The pharmaceutical compositions of the invention can be used for the treatment or prevention of cancer or infectious disease. |
| FILED | Thursday, October 26, 2017 |
| APPL NO | 15/795155 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/761 (20130101) A61K 39/0011 (20130101) A61K 39/0275 (20130101) A61K 2039/57 (20130101) A61K 2039/70 (20130101) A61K 2039/572 (20130101) A61K 2039/585 (20130101) A61K 2039/6068 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 14/255 (20130101) C07K 2319/00 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2710/10343 (20130101) Enzymes C12Y 306/03044 (20130101) Technologies for Adaptation to Climate Change Y02A 50/466 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316073 | Ulrichts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | argenx BVBA (Zwijnaarde, Belgium); The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | argenx BVBA (, Belgium); The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Peter Ulrichts (Destelbergen, Belgium); Christophe Blanchetot (Destelbergen, Belgium); Torsten Dreier (Sint Martens Latem, Belgium); Johannes de Haard (NA Oudelande, Netherlands); E. Sally Ward Ober (Dallas, Texas); Nicolas G. H. Ongenae (Ghent, Belgium) |
| ABSTRACT | Provided are novel FcRn antagonist compositions comprising a variant Fc region that binds specifically to FcRn with increased affinity and reduced pH dependence relative to the native Fc region. Also provided are FcRn antagonists with enhanced CD16 binding affinity. Also provided are methods of treating antibody-mediated disorders (e.g. autoimmune diseases) using the these FcRn antagonist compositions, nucleic acids encoding the FcRn antagonist compositions, recombinant expression vectors and host cells for making the FcRn antagonist compositions, and pharmaceutical compositions comprising the FcRn antagonist compositions. |
| FILED | Tuesday, December 23, 2014 |
| APPL NO | 14/580771 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1709 (20130101) A61K 45/06 (20130101) Peptides C07K 14/4703 (20130101) Original (OR) Class C07K 2317/41 (20130101) C07K 2317/52 (20130101) C07K 2317/94 (20130101) C07K 2317/524 (20130101) C07K 2317/526 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316075 | Vandenbark et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Arthur A. Vandenbark (Portland, Oregon); Roberto Meza-Romero (Hillsboro, Oregon); Gil Benedek (Portland, Oregon); Gregory G. Burrows (Portland, Oregon) |
| ABSTRACT | Recombinant polypeptides comprising a DRα1 domain, an antigenic peptide, and a linker sequence are disclosed. The linker sequence comprises a first glycine-serine spacer, a thrombin cleavage site and a second glycine-serine spacer. Further disclosed are pharmaceutical compositions comprising the recombinant polypeptides, methods of treating inflammatory disease using said pharmaceutical compositions, and expression constructs comprising nucleic acids that encode the recombinant polypeptides. |
| FILED | Friday, October 03, 2014 |
| APPL NO | 14/506502 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) A61K 2039/605 (20130101) A61K 2039/627 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 14/70539 (20130101) C07K 2319/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316083 | Michelsen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Kathrin S. Michelsen (Los Angeles, California); Stephan R. Targan (Santa Monica, California) |
| ABSTRACT | The present invention relates to the finding that TL1A enhances differentiation of TH17 cells, and enhance IL17 secretion from TH17 cells. In one embodiment, the present invention provides a method of treating an inflammatory disease comprising determining the presence of a TL1A signaling profile, and treating the disease by administering a composition comprising a therapeutically effective dosage of one or more inhibitors of TL1A or TH17 cell differentiation. In another embodiment, the disease is characterized by TH17 differentiation. |
| FILED | Friday, July 18, 2014 |
| APPL NO | 14/900024 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/241 (20130101) Original (OR) Class C07K 16/244 (20130101) C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/6863 (20130101) G01N 33/56966 (20130101) G01N 2015/149 (20130101) G01N 2333/70575 (20130101) G01N 2800/12 (20130101) G01N 2800/065 (20130101) G01N 2800/7095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316092 | Yao et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEDIMMUNE, LLC (Gaithersburg, Maryland); THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHN HOPKINS UNIVERSITY (Baltimore, Maryland); MEDIMMUNE, LLC (Gaitherburgh, Maryland) |
| INVENTOR(S) | Sheng Yao (Columbia, Maryland); Lieping Chen (Hampden, Connecticut); Linda Liu (Columbia, Maryland); Solomon Langermann (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to antibodies and their antigen-binding fragments and to other molecules that are capable of immunospecifically binding to the B7-H5 ligand of the B7-H5:CD28H pathway, and to the uses of such molecules in the treatment and diagnosis of autoimmune disease, transplant rejection and other inflammatory diseases. |
| FILED | Tuesday, May 27, 2014 |
| APPL NO | 14/893463 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/2827 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316094 | Maute et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Roy Louis Maute (San Francisco, California); Kipp Andrew Weiskopf (Sudbury, Massachusetts); Aaron Michael Ring (New Haven, Connecticut); Irving L. Weissman (Stanford, California) |
| ABSTRACT | Methods and compositions are provided for inducing phagocytosis of a target cell, treating an individual having cancer, treating an individual having an intracellular pathogen infection (e.g., a chronic infection), and/or reducing the number of inflicted cells (e.g., cancer cells, cells infected with an intracellular pathogen, etc.) in an individual. Methods and compositions are also provided for predicting whether an individual is resistant (or susceptible) to treatment with an anti-CD47/SIRPA agent. In some cases, the subject methods and compositions include an anti-MHC Class I/LILRB1 agent. In some cases, the subject methods and compositions include an anti-MHC Class I/LILRB1 agent and an anti-CD47/SIRPA agent (e.g., co-administration of an anti-MHC Class I/LILRB1 agent and an anti-CD47/SIRPA agent). Kits are also provided for practicing the methods of the disclosure. |
| FILED | Friday, October 23, 2015 |
| APPL NO | 15/518976 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1774 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/2803 (20130101) C07K 16/2833 (20130101) Original (OR) Class C07K 16/2863 (20130101) C07K 2317/24 (20130101) C07K 2317/55 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316287 | Gundry et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE MEDICAL COLLEGE OF WISCONSIN, INC. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Rebekah L. Gundry (Milwaukee, Wisconsin); Kenneth R. Boheler (Hong Kong, China PRC); Erin M. Kropp (Milwaukee, Wisconsin) |
| ABSTRACT | Provided herein are methods of reducing or eliminating undifferentiated pluripotent stem cells, where the methods comprise contacting an effective amount of a compound to a heterogeneous cell population or sample comprising or suspected of comprising differentiated cell types and undifferentiated pluripotent stem cells, whereby the contacting selectively reduces or eliminates undifferentiated pluripotent stem cells from the cell population or sample. Also provided are methods for obtaining a population of stem cell-derived cell types substantially free of undifferentiated pluripotent stem cells as well as isolated populations of such of stem cell-derived cell types. |
| FILED | Wednesday, January 21, 2015 |
| APPL NO | 15/112923 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/545 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0081 (20130101) Original (OR) Class C12N 5/0606 (20130101) C12N 5/0657 (20130101) C12N 5/0696 (20130101) C12N 2500/38 (20130101) C12N 2501/72 (20130101) C12N 2501/724 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316289 | Gattinoni et al. |
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| FUNDED BY |
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| APPLICANT(S) | Luca Gattinoni (Washington, District of Columbia); Enrico Lugli (Bethesda, Maryland); Mario Roederer (Washington, District of Columbia); Nicholas P. Restifo (Chevy Chase, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Luca Gattinoni (Washington, District of Columbia); Enrico Lugli (Bethesda, Maryland); Mario Roederer (Washington, District of Columbia); Nicholas P. Restifo (Chevy Chase, Maryland) |
| ABSTRACT | Provided are methods of producing an isolated T memory stem cell population, the method comprising a) isolating nave T cells from a mammal, wherein the mammal is not a mouse; b) activating the nave T cells and expanding the numbers of nave T cells in the presence of one or more non-specific T cell stimuli, one or more cytokines, and a GSK-3beta inhibitor. Also provided are methods of producing an isolated T memory stem cell population, the method comprising a) isolating lymphocytes from a mammal; b) sorting the lymphocytes using flow cytometry into a population comprising a phenotype comprising i) CD95+, CD45RO−, and CCR7+; and ii) CD62L+ or one or more of CD27+, CD28+, CD45RA+, and CD127+ to produce an isolated T memory stem cell population. Further embodiments of the invention provide related cells, populations of cells, pharmaceutical compositions, and methods of treating or preventing cancer. |
| FILED | Thursday, September 06, 2012 |
| APPL NO | 14/425713 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 2039/572 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2501/51 (20130101) C12N 2501/415 (20130101) C12N 2501/515 (20130101) C12N 2501/727 (20130101) C12N 2501/2302 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316294 | Mueller et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Steffen Mueller (Great Neck, New York); Eckard Wimmer (East Setauket, New York); Bruce Futcher (Stony Brook, New York); Steven Skiena (Setauket, New York); Chen Yang (Forest Hills, New York) |
| ABSTRACT | This invention provides highly attenuated influenza viruses and vaccines. The attenuated viruses and vaccines proliferate well and have high safety factors. The attenuated viruses providing protective immunity from challenge by virus of the same subtype, as well as cross protection against heterologous viruses. |
| FILED | Saturday, March 15, 2014 |
| APPL NO | 14/777204 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2760/16034 (20130101) C12N 2760/16061 (20130101) C12N 2760/16134 (20130101) C12N 2760/16162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316295 | Schmitt et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Anthony Paul Schmitt (State College, Pennsylvania); Phuong Tieu Schmitt (State College, Pennsylvania); Greeshma Vivekananda Ray (State College, Pennsylvania) |
| ABSTRACT | Provided are modified virus-like particles (VLPs) of paramyxoviruses, compositions containing them, methods of using the VLPs for delivery of any particular protein of interest to any of a variety of cells, kits that contain expression vectors for making, using and detecting VLPs, and methods for screening for anti-viral compounds using the VLPs. The modified VLPs contain a contiguous recombinant polypeptide that contains i) all or a segment of a C-terminal domain of a paramyxovirus nucleocapsid protein and ii) a polypeptide sequence of a distinct protein. Non-covalent complexes of paramyxovirus M protein and fusion proteins that contain a C-terminal domain of a paramyxovirus nucleocapsid protein and a polypeptide sequence of a distinct protein are provided, as are non-covalent complexes of cells, and cell receptors, with modified VLPs. |
| FILED | Monday, December 19, 2016 |
| APPL NO | 15/383324 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 14/8121 (20130101) C07K 16/1027 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/0069 (20130101) C12N 9/0089 (20130101) C12N 2760/18022 (20130101) C12N 2760/18023 (20130101) C12N 2760/18034 (20130101) C12N 2760/18222 (20130101) C12N 2760/18223 (20130101) C12N 2760/18234 (20130101) C12N 2760/18252 (20130101) C12N 2760/18722 (20130101) C12N 2760/18723 (20130101) C12N 2760/18734 (20130101) Enzymes C12Y 113/12005 (20130101) C12Y 115/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316334 | Picker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Louis Picker (Portland, Oregon); Scott Hansen (Portland, Oregon); Klaus Frueh (Portland, Oregon); Daniel Malouli (Hillsboro, Oregon) |
| ABSTRACT | CMV vectors comprising a heterologous protein antigen, an active UL131 protein (or an ortholog thereof), and an active UL128 protein (or an ortholog thereof) but lacking an active UL130 protein (or an ortholog thereof) are provided. CMV vectors comprising a heterologous protein antigen, an active UL131 protein (or an ortholog thereof), and an active UL130 protein (or an ortholog thereof) but lacking an active UL128 protein are also provided. In addition, methods of using CMV vectors to generate an immune response characterized as having at least 10% of the CD8+ T cells directed against epitopes presented by MHC Class II are provided. |
| FILED | Friday, September 01, 2017 |
| APPL NO | 15/693558 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 48/00 (20130101) A61K 2039/572 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2710/16011 (20130101) C12N 2710/16143 (20130101) C12N 2740/15034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316354 | Furst et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Ariel L. Furst (Pasadena, California); Michael G. Hill (Pasadena, California); Natalie B. Muren (Pasadena, California); Jacqueline K. Barton (San Marino, California) |
| ABSTRACT | A two-electrode detection system having target substrates including nucleic acids, proteins, and/or small molecules on specifically defined regions of a single surface. The spatial distribution of the target substrate on the surface allows for more accurate substrate interactions and analysis. Additionally, the detection system of the present invention allows for patterning of different target substrates, thereby affording more accurate analysis of multiple substrate targets. |
| FILED | Monday, July 14, 2014 |
| APPL NO | 14/331221 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6825 (20130101) C12Q 2523/115 (20130101) C12Q 2525/197 (20130101) C12Q 2563/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316361 | Sukumar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Saraswati V. Sukumar (Columbia, Maryland); Christopher Benedict Umbricht (Towson, Maryland); Antonio C. Wolff (Baltimore, Maryland); Mary Jo Steele Fackler (Hunt Valley, Maryland); Zhe Zhang (Columbia, Maryland); Leslie M. Cope (Baltimore, Maryland); Kala Visvanathan (Baltimore, Maryland); Peng Huang (Owings Mills, Maryland) |
| ASSIGNEE(S) | THE JOHN HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Saraswati V. Sukumar (Columbia, Maryland); Christopher Benedict Umbricht (Towson, Maryland); Antonio C. Wolff (Baltimore, Maryland); Mary Jo Steele Fackler (Hunt Valley, Maryland); Zhe Zhang (Columbia, Maryland); Leslie M. Cope (Baltimore, Maryland); Kala Visvanathan (Baltimore, Maryland); Peng Huang (Owings Mills, Maryland) |
| ABSTRACT | To better understand the biology of hormone receptor-positive and negative breast cancer and to identify methylated gene markers of disease progression, a genome-wide methylation array analysis was performed on 103 primary invasive breast cancers and 21 normal breast samples using the Illumina Infinium HumanMethylation27 array that queried 27,578 CpG loci. Forty CpG loci showed differential methylation specific to either ER-positive or ER-negative tumors. Each of the 40 ER-subtype-specific loci was validated in silico using an independent, publicly available methylome dataset from The Cancer Genome Atlas (TCGA). In addition, 100 methylated CpG loci were identified that were significantly associated with disease progression. Arrays containing the ER-subtype-specific loci and their use in methods of diagnosis and treatment of breast cancer are provided. |
| FILED | Monday, July 16, 2012 |
| APPL NO | 14/232981 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316365 | Chute et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | John Chute (Durham, North Carolina); Joseph Nevins (Durham, North Carolina); Holly Dressman (Durham, North Carolina); Nelson Chao (Durham, North Carolina) |
| ABSTRACT | The present invention relates, in general, to gene expression profiles, and in particular, to a peripheral blood gene expression profile of an environmental exposure, ionizing radiation. The invention further relates to methods of screening patients for radiation exposure based on gene expression profiling and to kits suitable for use in such methods. |
| FILED | Wednesday, November 27, 2013 |
| APPL NO | 14/092291 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 1/6881 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316368 | Klumpp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); The Board of Trustees of the University of Illinoi (Urbana, Illinois) |
| INVENTOR(S) | David J. Klumpp (Chicago, Illinois); Anthony J. Schaeffer (Hinsdale, Illinois); Bryan A. White (Champaign, Illinois) |
| ABSTRACT | Provided herein are kits, compositions, and methods for diagnosing and treating interstitial cystitis (IC) and/or interstitial cystitis/bladder pain syndrome (IC/BPS) based on finding lower levels of certain bacteria in a subject's stool sample (e.g., O. splanchnicus, F. prausnitzii, C. aerofaciens, E. sinensis, L. longoviformis, and R. intestinalis). In certain embodiments, then present invention provides probiotic formulations containing live bacteria (e.g., from O. splanchnicus, F. prausnitzii, C. aerofaciens, E. sinensis, L. longoviformis, and R. intestinalis). |
| FILED | Tuesday, October 10, 2017 |
| APPL NO | 15/729249 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 35/741 (20130101) A61K 2035/115 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6883 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317321 | Tillberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Paul Warren Tillberg (Cambridge, Massachusetts); Fei Chen (Cambridge, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Chih-Chieh Yu (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides a method termed protein retention ExM (proExM), in which proteins, rather than labels, are anchored to the swellable gel, using a cross-linking molecule. This proExM strategy can be used to perform nanoscale imaging of immunostained cells and tissues as well as samples expressing various FPs as fluorescent signals from genetically encoded fluorescent proteins and/or conventional fluorescently labeled secondary antibodies and streptavidin that are directly anchored to the gel are preserved even when subjected to the nonspecific proteolytic digestion. |
| FILED | Friday, August 05, 2016 |
| APPL NO | 15/229545 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) Original (OR) Class G01N 1/36 (20130101) G01N 33/582 (20130101) G01N 33/6803 (20130101) G01N 2001/302 (20130101) G01N 2001/307 (20130101) G01N 2333/95 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317361 | Mayer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Michael Mayer (Ann Arbor, Michigan); Erik Yusko (Seattle, Washington) |
| ABSTRACT | Physical parameters of macromolecules are determined by measuring electrical current I over time for translocation events as the macromolecules in solution move between two liquid compartments that are separated by and fluidically coupled through a synthetic nanopore. Values of charge, volume, shape, rotational diffusion coefficient, and dipole moment are derived from the measurements. |
| FILED | Thursday, January 26, 2017 |
| APPL NO | 15/416522 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4473 (20130101) Original (OR) Class G01N 27/44791 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10317364 — Method and apparatus for ion mobility separations utilizing alternating current waveforms
| US 10317364 | Garimella et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Venkata B S Garimella (Richland, Washington); Ahmed M. Hamid (Richland, Washington); Yehia M. Ibrahim (West Richland, Washington); Richard D. Smith (Richland, Washington) |
| ABSTRACT | Methods and apparatuses for ion manipulations, including ion trapping, transfer, and mobility separations, using traveling waves (TW) formed by continuous alternating current (AC) are disclosed. An apparatus for ion manipulation includes a surface to which are coupled a first plurality of continuous electrodes and a second plurality of segmented electrodes. The second plurality of segmented electrodes is arranged in longitudinal sets between or adjacent to the first plurality of electrodes. An RF voltage applied to adjacent electrodes of the first plurality of electrodes is phase shifted by approximately 180° to confine ions within the apparatus. An AC voltage waveform applied to adjacent electrodes within a longitudinal set of the second plurality of segmented electrodes is phase shifted on the adjacent electrodes by 1°-359° to move ions longitudinally through the apparatus for separation. |
| FILED | Monday, August 15, 2016 |
| APPL NO | 15/774837 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/624 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/26 (20130101) H01J 49/0027 (20130101) H01J 49/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317393 | Wong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Academia Sinica (Taipei, Taiwan) |
| ASSIGNEE(S) | ACADEMIA SINICA (Taipei, Taiwan) |
| INVENTOR(S) | Chi-Huey Wong (Rancho Santa Fe, California); Tsui-Ling Hsu (Taipei, Taiwan); Sarah R. Hanson (San Marcos, California); Masaaki Sawa (Ibaraki, Japan) |
| ABSTRACT | Methods for metabolic oligosaccharide engineering that incorporates derivatized alkyne-bearing sugar analogs as “tags” into cellular glycoconjugates are disclosed. Alkynyl derivatized Fuc and alkynyl derivatized ManNAc sugars are incorporated into cellular glycoconjugates. Chemical probes comprising an azide group and a visual or fluorogenic probe and used to label alkyne-derivatized sugar-tagged glycoconjugates are disclosed. Chemical probes bind covalently to the alkynyl group by Cu(I)-catalyzed [3+2] azide-alkyne cycloaddition and are visualized at the cell surface, intracellularly, or in a cellular extract. The labeled glycoconjugate is capable of detection by flow cytometry, SDS-PAGE, Western blot, ELISA, confocal microscopy, and mass spectrometry. |
| FILED | Tuesday, October 10, 2017 |
| APPL NO | 15/729317 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/533 (20130101) G01N 33/5005 (20130101) Original (OR) Class G01N 33/5008 (20130101) G01N 2400/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317395 | Singh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Ankur Singh (Ithaca, New York); Alberto Purwada (Ithaca, New York) |
| ABSTRACT | Provided are compositions and methods that relate ex vivo organoids that contain B cells and stromal cells in a three dimensional material includes a hydrogel. The hydrogel can be formed without exposure to ultraviolet light from an electronic ultraviolet light source. The hydrogel contains silicate nanoparticles (SiNPs) that are ionically bonded to a polyampholytic gelatin. The three dimensional material can be held at a temperature of at least 37 degrees Celsius and does not liquefy. The organoids exhibit mechanical properties that are similar to certain lymphoid tissues, and can include a germinal center. Methods of making the organoids are included, as are high throughput screening approaches that use the organoids for screening a variety of test agents. The organoids can synthesize a variety of compounds that can be recovered from the organoids or the organoid culture medium. |
| FILED | Wednesday, August 31, 2016 |
| APPL NO | 15/253078 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5088 (20130101) Original (OR) Class G01N 2333/47 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317404 | Campbell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Becton, Dickinson and Company (Franklin Lakes, New Jersey) |
| ASSIGNEE(S) | BECTON, DICKINSON AND COMPANY (Franklin Lakes, New Jersey) |
| INVENTOR(S) | Robert Campbell (Bullock, North Carolina); Kevin G. Dolan (Holly Springs, North Carolina); Eric Fallows (Apex, North Carolina); Randal A. Hoke (Cary, North Carolina); Ross Jacobson (Hillsborough, North Carolina); J. Bruce Pitner (Durham, North Carolina); Glenn P. Vonk (Fuquay Varina, North Carolina); Rajashaker Kache (Cary, North Carolina); Upma Gulati (Cary, North Carolina); Herman Himel (Cary, North Carolina); Rosemary B. Evans-Storms (Durham, North Carolina) |
| ABSTRACT | Some embodiments provided herein relate to combined assays. In some embodiments, an assay for identifying influenza type A or influenza type B is combined with an assay for determining the sensitivity of an influenza neuraminidase to an antiviral drug. |
| FILED | Tuesday, April 01, 2014 |
| APPL NO | 14/781008 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/203 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) Original (OR) Class G01N 2333/11 (20130101) G01N 2333/924 (20130101) G01N 2500/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317409 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hyesook Kim (Bloomfield Hills, Michigan); Sohee Kim (Seoul, South Korea) |
| ASSIGNEE(S) | Detroit R and D, Inc. (Detroit, Michigan) |
| INVENTOR(S) | Hyesook Kim (Bloomfield Hills, Michigan); Sohee Kim (Seoul, South Korea) |
| ABSTRACT | A method of characterizing the protein O-GlcNAcylation site-specificity of an antibody. A method of detecting or quantitating the expression of site-specific O-GlcNAcylated proteins expressed in cells and biological samples. A method of diagnosing cancer in a host based on the cellular expression of site-specific O-GlcNAcylated proteins. A method of screening anti-cancer compounds according to their ability to increase a level O-GlcNAcylation of oncogene or tumor suppressor proteins. Methods of treating cancer in an animal host by administering compounds that increase a level of O-GlcNAcylated c-myc or p53 in cancer cells. A method of distinguishing subclasses of pancreatic cancer according to the sensitivity of pancreatic cancer cells to an imidazole derivative, and a method of personalized pancreatic cancer treatment delivered according to the sensitivity subclasses. |
| FILED | Monday, March 03, 2014 |
| APPL NO | 14/195209 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/433 (20130101) A61K 31/496 (20130101) A61K 31/7076 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5091 (20130101) G01N 33/57415 (20130101) G01N 33/57419 (20130101) G01N 33/57423 (20130101) G01N 33/57438 (20130101) G01N 33/57496 (20130101) Original (OR) Class G01N 2400/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317417 | Saffitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Jeffrey E. Saffitz (Waban, Massachusetts); Angeliki Asimaki (Boston, Massachusetts) |
| ABSTRACT | Described herein are, inter alia, methods for diagnosing and treating arrhythmogenic cardiomyopathy (ACM) by detecting cardiac intercalated disk proteins, e.g., desmosomal proteins, mechanical and gap junction proteins, in buccal cells. Exemplary desmosomal and gap junction proteins that can be evaluated in the methods described herein include plakoglobin, plakophilin 1, desmoplakin, and Cx43. The methods can also include selecting and/or administering a treatment for ACM to the subject. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/979199 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2800/60 (20130101) G01N 2800/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317418 | Goosens |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ki Ann Goosens (Cambridge, Massachusetts) |
| ABSTRACT | The invention relates to methods of treating stress-sensitive psychiatric diseases arising from trauma in a subject by enhancing ghrelin signaling in the BLA of the subject. The invention also relates to methods of reversing ghrelin resistance. |
| FILED | Wednesday, February 24, 2016 |
| APPL NO | 15/052110 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/165 (20130101) A61K 31/395 (20130101) A61K 31/404 (20130101) A61K 31/415 (20130101) A61K 31/4439 (20130101) A61K 31/4545 (20130101) A61K 31/7076 (20130101) A61K 38/25 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) Original (OR) Class G01N 2800/30 (20130101) G01N 2800/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317597 | Cohen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Noy Cohen (Stanford, California); Marc S. Levoy (Stanford, California); Michael J. Broxton (San Francisco, California); Logan Grosenick (Brooklyn, New York); Samuel Yang (Stanford, California); Aaron Andalman (San Francisco, California); Karl A. Disseroth (Stanford, California); Mark A. Horowitz (Menlo Park, California) |
| ABSTRACT | Various aspects of the present disclosure are directed toward optics and imaging. As may be implemented with one or more embodiments, an apparatus includes one or more phase masks that operate with an objective lens and a microlens array to alter a phase characteristic of light travelling in a path from a specimen, through the objective lens and microlens array and to a photosensor array. Using this approach, the specimen can be imaged with spatial resolution characteristics provided via the altered phase characteristic, which can facilitate construction of an image with enhanced resolution. |
| FILED | Monday, August 17, 2015 |
| APPL NO | 14/828259 |
| ART UNIT | 2485 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 3/0006 (20130101) G02B 5/3083 (20130101) Original (OR) Class G02B 21/0056 (20130101) G02B 27/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318706 | Putnam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dovetail Genomics, LLC (Santa Cruz, California) |
| ASSIGNEE(S) | Dovetail Genomics, LLC (Santa Cruz, California) |
| INVENTOR(S) | Nicholas H. Putnam (Santa Cruz, California); Jonathan C. Stites (Santa Cruz, California); Brandon J. Rice (Santa Cruz, California) |
| ABSTRACT | Disclosed herein are compositions, systems and methods related to sequence assembly, such as nucleic acid sequence assembly of single reads and contigs into larger contigs and scaffolds through the use of read pair sequence information, such as read pair information indicative of nucleic acid sequence phase or physical linkage. |
| FILED | Monday, June 26, 2017 |
| APPL NO | 15/632895 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Electric Digital Data Processing G06F 19/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318863 | Lock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rehabilitation Institute of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | Rehabilitation Institute of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Blair Lock (Chicago, Illinois); Levi Hargrove (Chicago, Illinois) |
| ABSTRACT | Embodiments of the invention provide for a prosthesis guided training system that includes a plurality of sensors for detecting electromyographic activity. A computing device, which can include a processor and memory, can extract data from the electromyographic activity. A real-time pattern recognition control algorithm and an autoconfiguring pattern recognition training algorithm can be stored in the memory. The computing device can determine movement of a prosthesis based on the execution of the real-time pattern recognition control algorithm. The computing device can also alter operational parameters of the real-time pattern recognition control algorithm based on execution of the autoconfiguring pattern recognition training algorithm. |
| FILED | Wednesday, July 24, 2013 |
| APPL NO | 13/950000 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/04888 (20130101) A61B 5/7267 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) A61F 2/72 (20130101) A61F 2002/704 (20130101) A61F 2002/5036 (20130101) A61F 2002/7615 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/0265 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10319390 | Soleymani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Roozbeh Soleymani (New York, New York); Ivan W. Selesnick (Maplewood, New Jersey); David M. Landsberger (Forest Hills, New York) |
| ABSTRACT | A system and method for improving intelligibility of speech is provided. The system and method may include obtaining an input audio signal frame, classifying the input audio signal frame into a first category or a second category, wherein the first category corresponds to the noise being stronger than the speech signal, and the second category corresponds to the speech signal being stronger than the noise, decomposing the input audio signal frame into a plurality of sub-band components; de-noising each sub-band component of the input audio signal frame in parallel by applying a first wavelet de-noising method including a first wavelet transform and a predetermined threshold for the sub-band component, and a second wavelet de-noising method including a second wavelet transform and the predetermined threshold for the sub-band component, wherein the predetermined threshold for each sub-band component is based on at least one previous noise-dominant signal frame received by the receiving arrangement. |
| FILED | Wednesday, September 13, 2017 |
| APPL NO | 15/703721 |
| ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 19/0216 (20130101) G10L 21/0205 (20130101) Original (OR) Class G10L 21/0208 (20130101) G10L 2021/02087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320610 | Matni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Nikolai Matni (Pasadena, California); John Comstock Doyle (Pasadena, California) |
| ABSTRACT | Data network components and frameworks for the control and optimization of network traffic using layered architectures, according to embodiments of the invention, are disclosed. In one embodiment, a data network comprises a switch, a data link, a tracking processor, and a planning processor. The planning processor is configured to generate a reference trajectory by receiving a local system state from the tracking processor, calculating a reference trajectory by solving a planning problem, and sending the reference trajectory to the tracking processor. The tracking processor is configured to track the reference trajectory by determining a set of states of the switch over a time interval, sending a local system state to the planning processor, receiving the reference trajectory from the planning processor, computing a control action by solving a tracking problem based on the reference trajectory, determining an instruction based on the control action, and sending the instruction to the switch. |
| FILED | Monday, October 17, 2016 |
| APPL NO | 15/295507 |
| ART UNIT | 2479 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/147 (20130101) H04L 41/0823 (20130101) Original (OR) Class H04L 43/0876 (20130101) H04L 45/42 (20130101) H04L 49/25 (20130101) H04L 49/552 (20130101) Wireless Communication Networks H04W 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10314527 | Qiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Liangliang Qiang (Willimantic, Connecticut); Santhisagar Vaddiraju (Willimantic, Connecticut); Fotios Papadimitrakopoulos (West Hartford, Connecticut) |
| ABSTRACT | Disclosed herein is a sensor comprising a conduit; the conduit comprising an organic polymer; a working electrode; the working electrode being etched and decorated with a nanostructured material; a reference electrode; and a counter electrode; the working electrode, the reference electrode and the counter electrode being disposed in the conduit; the working electrode, the reference electrode and the counter electrode being separated from each other by an electrically insulating material; and wherein a cross-sectional area of the conduit that comprises a section of the working electrode, a section of the reference electrode and a section of the counter electrode is exposed to detect analytes. |
| FILED | Tuesday, August 02, 2016 |
| APPL NO | 15/226150 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1473 (20130101) A61B 5/1495 (20130101) A61B 5/14532 (20130101) A61B 5/14865 (20130101) Original (OR) Class A61B 2560/0223 (20130101) A61B 2562/04 (20130101) A61B 2562/028 (20130101) A61B 2562/125 (20130101) A61B 2562/0285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314723 | Gregg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rehabilitation Institute of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | Rehabilitation Institute of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Robert D. Gregg (Allen, Texas); Jon Sensinger (Chicago, Illinois) |
| ABSTRACT | Systems and methods for improved control of a lower limb device are disclosed. The lower limb may have one or more joints and one or more corresponding motors. In some embodiments, a center of pressure is calculated in order to enforce virtual constraints at the one or more joints of the lower limb device. The system utilizes one or more effective shapes, and each effective shape's corresponding error, in order to cause each joint motor to produce a torque that causes the joint to move according to a virtual constraint. The systems and methods result in improved control of lower limb devices. |
| FILED | Friday, May 23, 2014 |
| APPL NO | 14/286380 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/64 (20130101) A61F 2/68 (20130101) A61F 2/6607 (20130101) Original (OR) Class A61F 2002/607 (20130101) A61F 2002/704 (20130101) A61F 2002/7625 (20130101) A61F 2002/7635 (20130101) A61F 2002/7645 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314725 | Chestek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Cynthia Anne Chestek (Ann Arbor, Michigan); Melanie G. Urbanchek (Ann Arbor, Michigan); Paul S. Cederna (Milan, Michigan); Richard Brent Gillespie (Ann Arbor, Michigan); Nicholas B. Langhals (Ypsilanti, Michigan); Zachary Irwin (Ann Arbor, Michigan); Daniel C. Ursu (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure provides methods and systems for receiving, with processing circuitry of an implant device, an electrical signal from a free tissue graft attached to a portion of a nerve (e.g., a nerve branch or fascicle) through an electrical conductor in electrical communication with the free tissue graft (e.g., muscle graft), the nerve having reinnervated the free tissue graft. The electrical signal from the free tissue graft has a voltage amplitude of greater than or equal to about 150 microvolts. The processing circuitry stores signal data corresponding to the electrical signal from the free tissue graft in a memory accessible to the processing circuitry. |
| FILED | Friday, November 13, 2015 |
| APPL NO | 14/940703 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Original (OR) Class A61F 2/583 (20130101) A61F 2002/701 (20130101) A61F 2002/704 (20130101) A61F 2002/5058 (20130101) A61F 2002/5064 (20130101) A61F 2002/6827 (20130101) A61F 2002/6872 (20130101) A61F 2002/7635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314911 | Frey, II et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HealthPartners Research and Education (Minneapolis, Minnesota) |
| ASSIGNEE(S) | HealthPartners Research and Education (Minneapolis, Minnesota); The Henry M. Jackson Foundation for Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | William H. Frey, II (St. Paul, Minnesota); Leah Ranae Bresin Hanson (Vadnais Heights, Minnesota); Kimberly Byrnes (Gaithersburg, Maryland); Fiona Brabazon (Silver Springs, Maryland) |
| ABSTRACT | The present system is directed in several embodiments to a method of administration of a therapeutic composition for protection of the brain of a subject at risk of injury leading to traumatic brain injury (TBI) and/or treatment of injury to the brain resulting from TBI. The method includes administering one or more therapeutic compositions comprising an effective amount of insulin directly to the subject patient's CNS, with no to minimal systemic exposure. Preferably, this method comprises administration of an effective amount of insulin to the upper third of a patient's nasal cavity, thereby bypassing the patient's blood-brain barrier and delivering the therapeutic composition directly to the patient's central nervous system. |
| FILED | Monday, April 06, 2015 |
| APPL NO | 14/679667 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 38/28 (20130101) A61K 38/28 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314938 | Kaplan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Ballou Hall, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Ung-Jin Kim (Daejeon, South Korea); Jaehyung Park (Decatur, Georgia); Hyoung-Joon Jin (Seoul, South Korea) |
| ABSTRACT | The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels. |
| FILED | Thursday, February 16, 2017 |
| APPL NO | 15/434484 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/38 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 27/3604 (20130101) A61L 2430/02 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/003 (20130101) B29C 39/203 (20130101) B29C 55/005 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 7/01 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2089/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2007/00 (20130101) B29L 2009/00 (20130101) Peptides C07K 14/43536 (20130101) C07K 14/43586 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/07 (20130101) C08J 3/075 (20130101) C08J 5/18 (20130101) C08J 9/26 (20130101) C08J 9/28 (20130101) C08J 9/0061 (20130101) C08J 2201/0444 (20130101) C08J 2201/0504 (20130101) C08J 2205/022 (20130101) C08J 2389/00 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249921 (20150401) Y10T 442/10 (20150401) Y10T 442/60 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314941 | McKinley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Todd O. McKinley (Indianapolis, Indiana); James A. Martin (Iowa City, Iowa); Mitchell Coleman (Iowa City, Iowa); Tae-Hong Lim (Coralville, Iowa); Marc Brouillette (Coralville, Iowa) |
| ABSTRACT | Compositions comprising a reverse-temperature sensitive hydrogel comprising a biopolymer such as a polysaccharide and a synthetic polymer, and a compound in an amount that reversibly inhibits respiratory enzyme complex I, and methods of using the composition, are provided. |
| FILED | Tuesday, February 13, 2018 |
| APPL NO | 15/895518 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0024 (20130101) A61K 31/155 (20130101) A61K 31/515 (20130101) A61K 47/34 (20130101) A61K 47/36 (20130101) A61K 47/38 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) Original (OR) Class A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/50 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 2300/434 (20130101) A61L 2400/06 (20130101) A61L 2430/24 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) C08L 71/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10315643 | Shukla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oshkosh Defense, LLC (Oshkosh, Wisconsin) |
| ASSIGNEE(S) | Oshkosh Defense, LLC (Oshkosh, Wisconsin) |
| INVENTOR(S) | Deepak Shukla (Oshkosh, Wisconsin); Rongjun Zhang (Oshkosh, Wisconsin); Nader Nasr (Neenah, Wisconsin) |
| ABSTRACT | A method of operating a first electric machine and a second electric machine in a vehicle drive includes operating the vehicle drive in: a first operating mode by operating the first electric machine in a voltage mode and the second electric machine in a torque mode; and a second operating mode by operating the first electric machine in the torque mode and the second electric machine in the voltage mode. |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/274946 |
| ART UNIT | 3659 — Material and Article Handling |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 6/26 (20130101) B60K 6/34 (20130101) B60K 6/52 (20130101) B60K 6/365 (20130101) B60K 6/387 (20130101) B60K 6/445 (20130101) B60K 6/543 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 50/11 (20190201) Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 10/02 (20130101) B60W 10/06 (20130101) B60W 10/08 (20130101) B60W 20/10 (20130101) Original (OR) Class B60W 2510/06 (20130101) B60W 2510/08 (20130101) B60W 2510/081 (20130101) B60W 2510/0604 (20130101) B60W 2510/0638 (20130101) B60W 2520/10 (20130101) B60W 2710/06 (20130101) B60W 2710/08 (20130101) B60W 2710/021 (20130101) B60W 2710/083 (20130101) B60W 2710/0644 (20130101) B60W 2710/0677 (20130101) Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology B60Y 2200/92 (20130101) B60Y 2300/42 (20130101) B60Y 2300/43 (20130101) B60Y 2300/60 (20130101) B60Y 2300/72 (20130101) B60Y 2400/73 (20130101) Gearing F16H 1/28 (20130101) F16H 3/72 (20130101) F16H 3/727 (20130101) F16H 3/728 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/92 (20130101) Y02T 10/6239 (20130101) Y02T 10/6286 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 903/91 (20130101) Y10S 903/93 (20130101) Y10S 903/906 (20130101) Y10S 903/914 (20130101) Y10S 903/916 (20130101) Y10S 903/918 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10315742 | Kaufman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| ASSIGNEE(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| INVENTOR(S) | Amanda Kaufman (Manassas, Virginia) |
| ABSTRACT | A marine propeller is disclosed having two blades. The shape of the propeller blades remains constant through the radial position of the propeller blades. The blade length of the propeller blades changes as a function of the radial position of the propeller blade. The twist angle of each blade starts at approximately 63 degrees at the propeller hub (proximal end) and decreases to about 15 degrees at the blade tip (distal end). |
| FILED | Tuesday, August 22, 2017 |
| APPL NO | 15/682938 |
| ART UNIT | 3617 — Material and Article Handling |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 2702/04 (20130101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 2008/002 (20130101) Marine Propulsion or Steering B63H 1/26 (20130101) Original (OR) Class B63H 21/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10315749 | Walker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Leidos, Inc. (Reston, Virginia) |
| ASSIGNEE(S) | Leidos, Inc. (Reston, Virginia) |
| INVENTOR(S) | Howard Walker (San Diego, California); Scott Stewart (Escondido, California); Richard Holmes Griffey (Vista, California) |
| ABSTRACT | Marine vessel propulsor occlusion systems and devices made of novel fabrics formed from biodegradable and/or dissolvable materials, and methods of manufacturing and using the same are disclosed. The propulsor occlusion devices can slow and/or incapacitate a marine vessel without serious injury to occupants and without destroying the vessel's propulsion system. |
| FILED | Wednesday, March 16, 2016 |
| APPL NO | 15/071279 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Marine Propulsion or Steering B63H 25/00 (20130101) Original (OR) Class Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 3/007 (20130101) D04H 3/009 (20130101) D04H 3/018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316058 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhifeng Ren (Houston, Texas); Dong Cai (Houston, Texas); Zhen Yang (Houston, Texas); University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Zhifeng Ren (Houston, Texas); Dong Cai (Houston, Texas); Zhen Yang (Houston, Texas) |
| ABSTRACT | A method of extracting biomolecules from live cells comprising: introducing a plurality of magnetized carbon nanotubes (MCNTs) into a live cell, wherein the MCNTs penetrate the cell membrane under a magnetic force; spearing the MCNTs through the cell under the magnetic force, wherein a biomolecule attaches to at least a portion of the MCNTs to form a biomolecule loaded MCNT; removing at least a portion of the biomolecule loaded MCNTs from the cell under the magnetic force; and collecting at least a portion of the biomolecule loaded MCNTs. |
| FILED | Tuesday, August 04, 2015 |
| APPL NO | 15/501796 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 1/14 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54326 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316137 | Wilker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jonathan James Wilker (Lafayette, Indiana); Courtney Lynn Jenkins (Jefferson City, Missouri) |
| ABSTRACT | Poly[(3,4-dihydroxymandelic acid)-co-(lactic acid)] can be produced from renewable feedstocks, possesses tunable degradation, and can achieve adhesion strengths rivaling the performance of existing glues and adhesives. In one aspect, a polymer is presented. The polymer includes poly[(3,4-dihydroxymandelic acid)-co-(lactic acid)]. The polymer can be an adhesive. The adhesive is configured to have tunable degradation. The polymer is derived from renewable resources. The renewable resources can include any one of or a combination of starch, cellulose, hemicellulose, lignin, chitin, polyphenols, poly (isoprene), suberin, polyterpenes, polyterpenoids, polyhydroxyalkanoates, rosin-based polymers, triglyceride-based polymers, alginates, and/or proteins. |
| FILED | Friday, February 19, 2016 |
| APPL NO | 15/552429 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/06 (20130101) Original (OR) Class C08G 63/912 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 101/02 (20130101) C09J 103/02 (20130101) C09J 105/08 (20130101) C09J 105/14 (20130101) C09J 167/04 (20130101) C09J 189/00 (20130101) C09J 193/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316220 | Hawkes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Elliot W. Hawkes (San Francisco, California); David L. Christensen (Los Altos, California); Srinivasan Arul Suresh (Stanford, California); Mark R Cutkosky (Palo Alto, California) |
| ABSTRACT | A controllable adhesive for non-flat surfaces is provided. The device has a conformable (i.e. flexible) film and directly cast thereto a synthetic dry adhesive film. The synthetic dry adhesive film has elastomeric wedges. The conformable film is capable to deform to a non-flat surface. In one embodiment, the controllable adhesive has a first loading mechanism at one end of the controllable adhesive to apply load to the controllable adhesive. In another embodiment, forming a gripper, the controllable adhesive has a second controllable adhesive with a second loading mechanism, such that the first and second loading mechanism face each other and join a common point of loading. |
| FILED | Tuesday, January 12, 2016 |
| APPL NO | 14/993332 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/00 (20130101) Original (OR) Class C09J 7/22 (20180101) C09J 7/28 (20180101) C09J 183/04 (20130101) C09J 2201/28 (20130101) C09J 2201/122 (20130101) C09J 2201/162 (20130101) C09J 2201/626 (20130101) C09J 2400/226 (20130101) C09J 2483/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316446 | Kroger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael J. Kroger (Middletown, Rhode Island); Brian K. Amaral (Newport, Rhode Island); Robert F. Cutler, III (Tiverton, Rhode Island); Michael R. Williams (Richmond, Rhode Island); Charles A. Holicker (Swansea, Rhode Island); Eric A. Lee (Warwick, Rhode Island); Jason R. Bernier (Exeter, Rhode Island); Kathryn A. Best (Warwick, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Michael J. Kroger (Middletown, Rhode Island); Brian K. Amaral (Newport, Rhode Island); Robert F. Cutler, III (Tiverton, Rhode Island); Michael R. Williams (Richmond, Rhode Island); Charles A. Holicker (Swansea, Rhode Island); Eric A. Lee (Warwick, Rhode Island); Jason R. Bernier (Exeter, Rhode Island); Kathryn A. Best (Warwick, Rhode Island) |
| ABSTRACT | A strength member sewing machine is provided which comprises upper and lower feeder spools, a collection spool and idlers positioned on a support structure. A cord supply, a fabric shaper, a speed control and a pressure foot lift are positioned on the structure. Fabric from the spools is kept in tension with the idlers while moving toward the fabric shaper. The fabric from the upper spool is crimped while the fabric from the lower spool remains flat underneath the shaper. Between the fabric layers, pull cords are pulled through from the cord supply thru the fabric shaper. The fabric with crimps and with the pull cords inside the crimps is sewn to the fabric from the lower spool to create casings with a pull cord in the internal space of each casing. The joined fabrics with the pull cords are collected by the collection spool as a finished product. |
| FILED | Tuesday, September 26, 2017 |
| APPL NO | 15/715197 |
| ART UNIT | 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Sewing D05B 21/002 (20130101) D05B 29/12 (20130101) D05B 35/08 (20130101) D05B 55/10 (20130101) Original (OR) Class D05B 69/04 (20130101) D05B 73/12 (20130101) Ropes or Cables in General D07B 1/147 (20130101) D07B 5/005 (20130101) D07B 2301/4091 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316671 | Chakka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Pitchaiah Vijay Chakka (Avon, Connecticut); James D. Hill (Tolland, Connecticut); David R. Pack (Gilbert, Arizona) |
| ABSTRACT | A blade for a gas turbine engine includes a body that includes an airfoil that extends in a radial direction from a 0% span position near an airfoil base to a 100% span position at an airfoil tip. The airfoil includes a first portion near the airfoil base with a first density and includes a second portion near the airfoil tip with a second density. The second density is less than the first density. The second portion includes an increasing true chord length in the radial direction. |
| FILED | Friday, July 17, 2015 |
| APPL NO | 14/802512 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) Original (OR) Class F01D 5/28 (20130101) F01D 5/141 (20130101) F01D 5/147 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/211 (20130101) F05D 2300/1723 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316683 | Palmer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Paul W Palmer (South Glastonbury, Connecticut) |
| ABSTRACT | A clearance control system for a gas turbine engine includes a full hoop blade outer air seal carrier ring, a full hoop thermal control ring at least partially contained within the full hoop blade outer air seal blade outer air seal carrier ring to form an interference fit therebetween, and a multiple of blade outer air seals mounted to the full hoop blade outer air seal carrier ring. |
| FILED | Wednesday, February 11, 2015 |
| APPL NO | 14/619419 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 11/16 (20130101) F01D 11/18 (20130101) Original (OR) Class F01D 25/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316684 | Duguay |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Brian Duguay (Berwick, Maine) |
| ABSTRACT | An active clearance control system for a gas turbine engine includes an air seal segment and a puller engageable with the air seal segment. |
| FILED | Thursday, February 06, 2014 |
| APPL NO | 14/781456 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/20 (20130101) Original (OR) Class F01D 11/22 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316685 | Davis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Timothy M. Davis (Kennebunk, Maine); Brian Duguay (Berwick, Maine) |
| ABSTRACT | An active clearance control system of a gas turbine engine includes a multiple of blade outer air seal assemblies and a multiple of rotary ramps. Each of the multiple of rotary ramps is associated with one of the multiple of blade outer air seal assemblies. A method of active blade tip clearance control for a gas turbine engine is provided. The method includes rotating a multiple of rotary ramps to control a continuously adjustable radial position for each of a respective multiple of blade outer air seal assemblies. |
| FILED | Friday, August 01, 2014 |
| APPL NO | 15/024686 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316698 | Candelori et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | David J. Candelori (Glastonbury, Connecticut); Brandon Spangler (Vernon, Connecticut) |
| ABSTRACT | A system for circumferentially distributing debris in a gas turbine engine includes a component that defines a component cooling channel that has an opening and is configured to receive a cooling airflow. The system also includes a casing at least partially enclosing the component. The system also includes a debris distribution surface positioned radially between the casing and the opening. |
| FILED | Monday, May 23, 2016 |
| APPL NO | 15/161807 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 11/08 (20130101) F01D 19/00 (20130101) F01D 25/005 (20130101) F01D 25/12 (20130101) F01D 25/32 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/202 (20130101) F05D 2260/607 (20130101) F05D 2300/17 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316751 | Hagan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Benjamin F. Hagan (Manchester, Connecticut); Ryan Alan Waite (Glastonbury, Connecticut) |
| ABSTRACT | a gas turbine engine structure includes a body radially spanning an inner portion and an outer portion. The structure body includes a first passage interior to the structure body. The first passage includes a first opening on one of a radially outward edge and a radially inward edge of the structure, and a second opening on the other of the radially outward edge and the radially inward edge of the structure. A second passage is also included interior to the structure. The second passage is approximately aligned with the first passage, and is disposed between the first passage and one of the first surface and the second surface of the structure. The second passage insulates the first passage from heat transfer through one of the first surface and the second surface. |
| FILED | Thursday, August 27, 2015 |
| APPL NO | 14/837398 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) F01D 5/187 (20130101) F01D 9/04 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 7/18 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/202 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316900 | Bouton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | ROLLS-ROYCE CORPORATION (Indianapolis, Indiana) |
| INVENTOR(S) | Matthew Tyler Bouton (Indianapolis, Indiana); Kevin Beckner (Indianapolis, Indiana); Andy Copeland (Greenwood, Indiana); Matt Starr (Indianapolis, Indiana); Doug Schwerin (Zionsville, Indiana); Kyle Hassler (Pittsboro, Indiana) |
| ABSTRACT | A clutch for a lift fan comprises at least one output shaft lug key positioned in a keyway of at least two output clutch plates and extending axially from one to the other of the two output clutch plates. The output shaft lug key couples the rotation of the output clutch plates to the rotation an output shaft and allows axial movement of the two output clutch plates relative the output shaft lug key. The width of an inner surface of the output shaft lug key varies along the axial length as a function of the proximity to a home axial position of each of the output clutch plates when in the disengaged position. |
| FILED | Monday, March 06, 2017 |
| APPL NO | 15/450842 |
| ART UNIT | 3659 — Material and Article Handling |
| CURRENT CPC | Aeroplanes; Helicopters B64C 29/0025 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/10 (20130101) B64D 35/00 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/36 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/90 (20130101) F05D 2260/4023 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 1/0864 (20130101) F16D 1/0876 (20130101) F16D 13/38 (20130101) Original (OR) Class F16D 13/52 (20130101) F16D 13/69 (20130101) F16D 13/646 (20130101) F16D 2200/0039 (20130101) F16D 2250/0046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317085 | Hannwacker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | David Andrew Hannwacker (Torrance, California); Stephen John Howell (West Newbury, Massachusetts); John Carl Jacobson (Melrose, Massachusetts) |
| ABSTRACT | A combustor assembly for a gas turbine engine includes a combustor dome having a hot side and a cold side and at least in part defining a combustion chamber. The combustor assembly additionally includes a fuel-air injector hardware assembly having a first member and a second member. The first member is positioned at least partially adjacent to the cold side of the combustor dome and the second member is positioned at least partially adjacent to the hot side of the combustor dome. The first and second members together define an attachment interface joining the first member to the second member and mounting the fuel-air injector hardware assembly to the combustor dome. The attachment interface may be shielded from the combustion chamber to protect the attachment interface from an undesirable amount of thermal expansion and to maintain the materials within desired material operating temperature limits. |
| FILED | Thursday, February 25, 2016 |
| APPL NO | 15/053522 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/20 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/14 (20130101) F23R 3/60 (20130101) Original (OR) Class F23R 3/283 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317150 | McCaffrey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Michael G McCaffrey (Windsor, Connecticut); Matthew A Devore (Rocky Hill, Connecticut) |
| ABSTRACT | A staged high temperature heat exchanger (HEX) may comprise a first stage made from a first material and a second stage made from a second material. The first stage may comprise an inlet manifold configured to receive a flow of fluid. The second stage may comprise an outlet manifold whereby the flow of fluid exits the HEX. The first stage is configured to withstand the temperature of the flow of fluid entering the inlet manifold and configured to reduce the temperature of the flow of fluid to an intermediate temperature before the flow of fluid reaches the second stage. In various embodiments, the first material may comprise a nickel-based superalloy having at least 40% of a Ni3(Al,X) precipitate phase, X being a metallic or refractory element other than Al. |
| FILED | Monday, November 21, 2016 |
| APPL NO | 15/357467 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) Jet-propulsion Plants F02K 3/115 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2250/75 (20130101) F05D 2260/213 (20130101) F05D 2300/175 (20130101) F05D 2300/177 (20130101) F05D 2300/607 (20130101) F05D 2300/1723 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/05316 (20130101) F28D 1/05325 (20130101) F28D 2021/0026 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 9/02 (20130101) F28F 21/087 (20130101) Original (OR) Class F28F 2265/00 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317178 | Burkart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph Burkart (Bloomfield, Indiana); Lucius A. Taylor, IV (French Lick, Indiana) |
| ABSTRACT | Various embodiments of optimized subsonic projectiles are provided along with related methods. For example, one exemplary subsonic projectile can include an elliptical nose cone, a cylindrical body and a boattail with various design features that can be used in a subsonic ammunition cartridge where the subsonic projectile is stabile throughout at least a segment of a flight allowing for better accuracy, maintaining low drag, maximizing range and achieving desired performance while ensuring the projectile stays below the speed of sound and lowering a noise profile of projectile and a launcher firing the projectile. |
| FILED | Saturday, November 28, 2015 |
| APPL NO | 14/953315 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 1/00 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/02 (20130101) Original (OR) Class F42B 10/00 (20130101) F42B 10/22 (20130101) F42B 10/24 (20130101) F42B 10/32 (20130101) F42B 10/38 (20130101) F42B 10/44 (20130101) F42B 33/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317182 | Elalem et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mohamed Elalem (Carteret, New Jersey); Philip Abbate (Long Valley, New Jersey); Vincent Gonsalves (Nazareth, Pennsylvania); Matthew P. Evangelisti (Denville, New Jersey); John W. Grassia (Andover, New Jersey); Steve Kotefski (Bloomingdale, New Jersey); Nikola Kotefski (Bloomingdale, New Jersey); Ming-Wan Young (Basking Ridge, New Jersey); Fei Shen (North Arlington, New Jersey); Chong Peng (Harrison, New Jersey); Linjie Zhu (Livingston, New Jersey); Viral Panchal (Parlin, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Mohamed Elalem (Carteret, New Jersey); Philip Abbate (Long Valley, New Jersey); Vincent Gonsalves (Nazareth, Pennsylvania); Matthew P. Evangelisti (Denville, New Jersey); John W. Grassia (Andover, New Jersey); Steve Kotefski (Bloomingdale, New Jersey); Nikola Kotefski (Bloomingdale, New Jersey); Ming-Wan Young (Basking Ridge, New Jersey); Fei Shen (North Arlington, New Jersey); Chong Peng (Harrison, New Jersey); Linjie Zhu (Livingston, New Jersey); Viral Panchal (Parlin, New Jersey) |
| ABSTRACT | A safety fuze for use in military and commercial applications, includes a fuze body that is attached to a trigger mechanism, an energetic train contained within the fuze body, and a non-energetic fuze delay mixture that is formed in a rod form so that it can dropped inside the fuze body, without modification to the other components of the safety fuze. Preferably, the non-energetic fuze delay mixture is made of foamed celluloid. |
| FILED | Thursday, March 12, 2015 |
| APPL NO | 14/656005 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 27/00 (20130101) F42B 27/08 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 9/10 (20130101) Original (OR) Class F42C 9/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317210 | Kub et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
| ASSIGNEE(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts); The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Francis J. Kub (Arnold, Maryland); Karl D. Hobart (Alexandria, Virginia); Eugene Imhoff (Washington, District of Columbia); Rachael Myers-Ward (Springfield, Virginia); Eugene H. Cook (Acton, Massachusetts); Marc S. Weinberg (Needham, Massachusetts); Jonathan J. Bernstein (Medfield, Massachusetts) |
| ABSTRACT | According to one aspect, embodiments herein provide a gyroscope comprising an axially symmetric structure, and a plurality of transducers, each configured to perform at least one of driving and sensing motion of the axially symmetric structure, wherein the plurality of transducers is configured to drive the axially symmetric structure in at least a first vibratory mode and a second vibratory mode, and wherein the gyroscope is implemented on a hexagonal crystal-based substrate. |
| FILED | Friday, May 20, 2016 |
| APPL NO | 15/160433 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5684 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317257 | Cunningham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Cunningham (West Hartford, Connecticut); Brett R. Hackleman (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Cunningham (West Hartford, Connecticut); Brett R. Hackleman (Scottsdale, Arizona) |
| ABSTRACT | A system for implementing a situational awareness includes a plurality of data gathering devices for observing the physical environment and transforming observations of physical phenomena into digital information; a plurality of field monitoring units with each of the plurality of units communicating with a corresponding plurality of data gathering devices to obtain data therefrom; and an aggregate monitoring unit communicating with each of the plurality of field monitoring units to monitor and control each of the plurality of field monitoring units and collect and store data from the plurality of data gathering devices. |
| FILED | Friday, February 05, 2016 |
| APPL NO | 15/016871 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 9/32 (20130101) Original (OR) Class Electric Digital Data Processing G06F 16/29 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317313 | Becker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ASCENDANT ENGINEERING SOLUTIONS (Austin, Texas) |
| ASSIGNEE(S) | Ascendant Engineering Solutions (Austin, Texas) |
| INVENTOR(S) | Keith Eric Becker (Georgetown, Texas); George Gregory Mooty (Austin, Texas) |
| ABSTRACT | Embodiments of the present invention are directed to an apparatus, system and associated method of operation that allows medium weight Class II equipment to be shock tested using a Medium Weight Shock Machine (MWSM) in a manner that adequately simulates the required shock response exhibited when subjected to underwater explosion (UNDEX), Heavyweight testing utilizing a FSP. Advantageously, such an apparatus, system and associated method allows for testing of Class II medium weight (e.g., about 500-4500 lbs.) equipment (e.g., submarine and surface vessel equipment) utilizing an MWSM instead of Heavyweight testing utilizing a Floating Shock Platform (FSP). Testing of Class II medium weight equipment in this manner significantly reduces cost of testing such equipment and increases safety associated with testing such equipment. |
| FILED | Tuesday, November 08, 2016 |
| APPL NO | 15/346108 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 7/08 (20130101) Original (OR) Class G01M 10/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317323 | Haldeman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bell Helicopter Textron Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | Bell Helicopter Textron Inc. (Fort Worth, Texas) |
| INVENTOR(S) | Andrew Paul Haldeman (Forth Worth, Texas); Ramesh Thiagarajan (Plano, Texas); Suvankar Mishra (Carrollton, Texas) |
| ABSTRACT | Systems and methods of operating a test apparatus to simulate testing a production aircraft component include assembling a test assembly having a test specimen and a wear protection material disposed on opposing sides of the test specimen, an outer plate disposed on each side of the test specimen in contact with the wear protection material, and a bolt disposed through the test specimen and the outer plates and applying a preload against the wear protection material. The test assembly is secured in a test machine, and the test machine is operated to provide a predetermined displacement of the test specimen relative to the outer plates at a predetermined frequency at a determined frequency of displacement cycles. The preload, the predetermined displacement, and the predetermined frequency of displacement cycles are determined through finite element analysis of an analytical model of the production component. |
| FILED | Thursday, October 12, 2017 |
| APPL NO | 15/782677 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/00 (20130101) G01N 1/08 (20130101) G01N 3/00 (20130101) G01N 3/08 (20130101) Original (OR) Class G01N 2201/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317418 | Goosens |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ki Ann Goosens (Cambridge, Massachusetts) |
| ABSTRACT | The invention relates to methods of treating stress-sensitive psychiatric diseases arising from trauma in a subject by enhancing ghrelin signaling in the BLA of the subject. The invention also relates to methods of reversing ghrelin resistance. |
| FILED | Wednesday, February 24, 2016 |
| APPL NO | 15/052110 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/165 (20130101) A61K 31/395 (20130101) A61K 31/404 (20130101) A61K 31/415 (20130101) A61K 31/4439 (20130101) A61K 31/4545 (20130101) A61K 31/7076 (20130101) A61K 38/25 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) Original (OR) Class G01N 2800/30 (20130101) G01N 2800/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317501 | Sarracanie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mathieu Sarracanie (Basel, Switzerland); Matthew Rosen (Somerville, Massachusetts); Ouri Cohen (Teaneck, New Jersey); Lionel Broche (Aberdeen, United Kingdom) |
| ABSTRACT | Systems and methods for magnetic resonance fingerprinting (“MRF”) using highly differentiated trajectories that optimize differentiation between magnetic resonance signal patterns as a function of relaxation time(s) and static magnetic field homogeneity are described. Using the optimized acquisition parameters, MRF can be performed in the presence of inhomogeneous magnetic fields. Flip angle homogeneity can also be incorporated into the dictionary matching process to simultaneously estimate quantitative parameters of the subject and radio frequency coil transmission homogeneity profiles. |
| FILED | Wednesday, July 26, 2017 |
| APPL NO | 15/660221 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/482 (20130101) G01R 33/3614 (20130101) G01R 33/5615 (20130101) G01R 33/5616 (20130101) G01R 33/5659 (20130101) G01R 33/56563 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317532 | Jannson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Physical Optics Corporation (Torrance, California) |
| ASSIGNEE(S) | PHYSICAL OPTICS CORPORATION (Torrance, California) |
| INVENTOR(S) | Tomasz Jannson (Torrance, California); Ranjit Pradhan (Torrance, California); Andrew Kostrzewski (Torrance, California) |
| ABSTRACT | A laser is used to emit a diverging laser flash configured to illuminate a detection zone. A pseudoimaging optical receiver system is used to detect reflections from objects in the detection zone. The receiver system includes a time-gated photodetector array that is used to record signatures in a voxel array. A voxel processing module receives the voxel array and detects a reference clutter signal within the array. Potential targets are then detected according to target signals in relation to the reference clutter signal. |
| FILED | Monday, June 26, 2017 |
| APPL NO | 15/633380 |
| ART UNIT | 2484 — Recording and Compression |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/66 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317581 | Govorov |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio University (Athens, Ohio) |
| ASSIGNEE(S) | Ohio University (Athens, Ohio) |
| INVENTOR(S) | Alexander Govorov (Athens, Ohio) |
| ABSTRACT | A composition includes a first population of strongly plasmonic nanorods and a second population of strongly plasmonic nanorods. The two populations each have a size range of the nanorods, creating a size range gap between the two populations. This size range gap creates a transparency window that can be seen in an extinction spectrum of the composition, which is characterized by the sizes of the nanorods in both populations. The composition may be included in a filter providing a transparency to a defined wavelength characterized by the size range gap of the nanorods. |
| FILED | Friday, March 27, 2015 |
| APPL NO | 15/129454 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/008 (20130101) Original (OR) Class G02B 5/22 (20130101) G02B 5/208 (20130101) G02B 27/0012 (20130101) G02B 2207/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317930 | Amir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Arnon Amir (Saratoga, California); Pallab Datta (San Jose, California); Nimrod Megiddo (Palo Alto, California); Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | A computer-implemented method is provided for optimizing core utilization in a neurosynaptic network. The computer-implemented method comprises identifying one or more unused portions of a neurosynaptic network. Additionally, the computer-implemented method comprises, for each of the one or more unused portions of the neurosynaptic network, disconnecting the unused portion from the neurosynaptic network. |
| FILED | Wednesday, September 30, 2015 |
| APPL NO | 14/871680 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Optical Computing Devices; G06E 1/00 (20130101) Original (OR) Class G06E 3/00 (20130101) Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317962 | Bose et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Pradip Bose (Yorktown Heights, New York); Alper Buyuktosunoglu (White Plains, New York); Timothy Joseph Chainer (Putnam Valley, New York); Pritish Ranjan Parida (Fishkill, New York); Augusto Javier Vega (Astoria, New York) |
| ABSTRACT | Techniques for inducing heterogeneous microprocessor behavior using non-uniform cooling are described. According to an embodiment, a device is provided that comprises an IC chip comprising a plurality of cores and a cooling apparatus coupled to the integrated chip that cools the integrated chip in association with electrical operation of the plurality of cores. The cooling apparatus cools a first core of the plurality of cores to a lower temperature than a second core of the plurality of cores. In various embodiments, the cooling apparatus comprises a plurality of channels embedded within the integrated chip and the cooling apparatus cools the integrated chip via flow of liquid coolant through the plurality of channels. |
| FILED | Tuesday, August 16, 2016 |
| APPL NO | 15/238452 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 1/206 (20130101) Original (OR) Class G06F 1/324 (20130101) G06F 1/3206 (20130101) G06F 2200/201 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/16 (20180101) Y02D 10/126 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318256 | Bruening et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VMware, Inc. (Palo Alto, California) |
| ASSIGNEE(S) | VMware, Inc. (Palo Alto, California) |
| INVENTOR(S) | Derek Bruening (Troy, New York); Vladimir L. Kiriansky (Alameda, California) |
| ABSTRACT | Computer code from an application program comprising a plurality of modules that each comprise a separately loadable file is code cached in a shared and persistent caching system. A shared code caching engine receives native code comprising at least a portion of a single module of the application program, and stores runtime data corresponding to the native code in a cache data file in the non-volatile memory. The engine then converts cache data file into a code cache file and enables the code cache file to be pre-loaded as a runtime code cache. These steps are repeated to store a plurality of separate code cache files at different locations in non-volatile memory. |
| FILED | Tuesday, November 27, 2012 |
| APPL NO | 13/686009 |
| ART UNIT | 2191 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/41 (20130101) Original (OR) Class G06F 12/0862 (20130101) G06F 12/1491 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318259 | Zhang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Yongzhi Zhang (Wayland, Massachusetts) |
| ABSTRACT | An apparatus for automatically converting a control flow program into a data flow program comprises a non-transitory machine-readable medium and a translator stored in the machine-readable medium. The translator, when executed by a data processing system, enables the data processing system to (a) automatically generate a control dependency graph for a control flow program, (b) automatically generate a data flow graph based at least in part on the control dependency graph, and (c) automatically generate a data flow program based at least in part on the data flow graph. In one embodiment or scenario, the translator may also automatically insert a switch instruction into the data flow program, in response to a determination that a variable of the control flow program is defined in one control dependency region and used in a different control dependency region. Other embodiments are described and claimed. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 15/609583 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/20 (20130101) G06F 8/34 (20130101) G06F 8/433 (20130101) Original (OR) Class G06F 15/825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318526 | Dean et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zymergen Inc. (Emeryville, California) |
| ASSIGNEE(S) | Zymergen Inc. (Emeryville, California) |
| INVENTOR(S) | Jed Dean (Lafayette, California); Adam Safir (Berkeley, California); Gregory Michael Werner (Fremont, California) |
| ABSTRACT | Systems and methods for enabling construction of complex Boolean chemical substructure queries in a structured graphical user interface are provided. The chemical substructures (molecules) may be represented graphically in standard molecular notation, and may be arranged horizontally and vertically on the interface, along with Boolean logical operators. Boolean logical operators of a first type may logically associate molecules arranged in horizontal fashion to form row queries, whereas Boolean logical operators of a different, second type may logically associate the row queries to form a composite query to be applied to a database of molecules. The operators of the first type may comprise disjunctive operators, whereas the operators of the second type may comprise conjunctive operators. |
| FILED | Tuesday, July 05, 2016 |
| APPL NO | 15/202439 |
| ART UNIT | 2164 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/248 (20190101) G06F 16/2246 (20190101) G06F 16/2282 (20190101) G06F 16/2428 (20190101) Original (OR) Class G06F 16/2456 (20190101) G06F 19/709 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318672 | Koizumi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arkansas State University Jonesboro (State University, Arkansas) |
| ASSIGNEE(S) | Arkansas State University Jonesboro (Jonesboro, Arkansas) |
| INVENTOR(S) | Hideya Koizumi (Jonesboro, Arkansas); Kenichiro Saito (Tokyo, Japan) |
| ABSTRACT | The system effectively manipulates the operation of a charged particle flow device by approximating the total force on each ion during a trajectory calculation. The system applies the method in massively parallel general-purpose computing with GPU (GPGPU) to test its performance in simulations with thousands to over a million ions. The method calculates the forces on an ion using ions within an active region near the ion of interest. To decrease computation time, the method approximates the forces by calculating the ion-ion interactions within a first zone and the ion-ion cloud interactions within a second zone. The system adjusts settings of the charged particle flow device to affect the flow and positioning of the charged particles. Such setting may include adjusting the positioning of the charged plates, adjusting the voltage of the plates, and adjusting the pressure within the charged particle flow device. |
| FILED | Thursday, February 02, 2017 |
| APPL NO | 15/423525 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class G06F 2217/16 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318798 | Majumdar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOOZ ALLEN HAMILTON INC. (McLean, Virginia) |
| ASSIGNEE(S) | BOOZ ALLEN HAMILTON INC. (McLean, Virginia) |
| INVENTOR(S) | Zigurts K. Majumdar (Washington, District of Columbia); Paul C. D'Angio (Arlington, Virginia); Michael A. Papazoglou (Chapel Hill, North Carolina); Allan Steinhardt (Vienna, Virginia); Christopher Hutchens (Leesburg, Virginia) |
| ABSTRACT | A method and device are provided for detecting non-visible content of an object in a non-contact manner. The device includes a light source configured to emit light toward a surface of an object over a period of time. The device also includes an optical sensing component configured to receive a pattern of light from the surface of the object, and to record the received pattern at plural points in time. In addition, the device includes a processing component configured to determine temporal changes in the pattern during the plural points in time, and to detect whether motion is present in the object based on determined temporal changes in the pattern, where the motion represents a frequency source of non-visible content in the object. |
| FILED | Friday, July 10, 2015 |
| APPL NO | 14/796343 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/14 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00335 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/262 (20170101) G06T 2207/30232 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318862 | Appuswamy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Rathinakumar Appuswamy (San Jose, California); Myron D. Flickner (San Jose, California); Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | Embodiments of the present invention provide a method for feature extraction comprising generating synaptic connectivity information for a neurosynaptic core circuit. The core circuit comprises one or more electronic neurons, one or more electronic axons, and an interconnect fabric including a plurality of synapse devices for interconnecting the neurons with the axons. The method further comprises initializing the interconnect fabric based on the synaptic connectivity information generated, and extracting a set of features from input received via the electronic axons. The set of features extracted comprises a set of features with reduced correlation. |
| FILED | Tuesday, May 15, 2018 |
| APPL NO | 15/980612 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0635 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10319098 | Nash et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Stephen R. Nash (Los Angeles, California); Christopher A. Leddy (Huntington Beach, California); Hector A. Quevedo (Redondo Beach, California) |
| ABSTRACT | A system for processing video signal information to identify those pixels associated with a moving object in the presence of platform and/or sensor pointing induced motion. Frame differencing with self-adjusting noise thresholds is implemented to detect pixels associated with objects that are in motion with respect to the background and a field-by-field motion pixel map of pixels associated with the moving object is generated. A two (2) step pixel grouping process is used where the first pass runs in real-time as the video signal is received and writes the links between pixel groups into entries in a table. The second pass operates on a smaller set of link data and only needs to reorder entries in the table. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/119088 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/20 (20130101) G06T 7/74 (20170101) G06T 7/215 (20170101) Original (OR) Class G06T 2207/20128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10319537 | Claussen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jonathan Clay Claussen (San Diego, California); Anurag Kumar (West Lafayette, Indiana); Timothy S. Fisher (West Lafayette, Indiana); Ronald G. Reifenberger (Lafayette, Indiana); Guoping Xiong (West Lafayette, Indiana); David Benjamin Jaroch (Tonawanda, New York); David Marshall Porterfield (West Lafayette, Indiana); Rajib Paul (Kaliyaganj, India) |
| ABSTRACT | A method of graphitic petal synthesis includes a step of providing a flexible carbon substrate, such as that including carbon microfibers. The method further includes the step of subjecting flexible carbon substrate to microwave plasma enhanced chemical vapor deposition. The resulting synthesized graphitic petal structure may optionally be coated with PANI. |
| FILED | Friday, February 14, 2014 |
| APPL NO | 14/181106 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/15 (20170801) C01B 32/18 (20170801) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3272 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/30 (20130101) H01G 11/36 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/587 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/742 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10319825 | Terrones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Humberto Terrones (State College, Pennsylvania); Mauricio Terrones (State College, Pennsylvania); Ana Laura Elias (State College, Pennsylvania); Nestor Perea-Lopez (State College, Pennsylvania) |
| ABSTRACT | A TMD system in which the first layered material is made of heterobilayers or multilayers with semiconducting direct band gaps is provided. The first layered material may be made of multiple layers of different TMD with different stackings, exhibiting smaller direct and indirect band gaps smaller than monolayer systems of TMD. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/724612 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/768 (20130101) H01L 21/02485 (20130101) H01L 21/02499 (20130101) H01L 21/02507 (20130101) H01L 21/02568 (20130101) H01L 21/28556 (20130101) H01L 29/24 (20130101) H01L 29/45 (20130101) Original (OR) Class H01L 29/417 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10319881 | Shatalov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sensor Electronic Technology, Inc. (Columbia, South Carolina) |
| ASSIGNEE(S) | Sensor Electronic Technology, Inc. (Columbia, South Carolina) |
| INVENTOR(S) | Maxim S. Shatalov (Columbia, South Carolina); Alexander Dobrinsky (Loudonville, New York); Michael Shur (Latham, New York); Remigijus Gaska (Columbia, South Carolina) |
| ABSTRACT | A profiled surface for improving the propagation of radiation through an interface is provided. The profiled surface includes a set of large roughness components providing a first variation of the profiled surface having a characteristic scale approximately an order of magnitude larger than a target wavelength of the radiation. The set of large roughness components can include a series of truncated shapes. The profiled surface also includes a set of small roughness components superimposed on the set of large roughness components and providing a second variation of the profiled surface having a characteristic scale on the order of the target wavelength of the radiation. |
| FILED | Monday, December 26, 2016 |
| APPL NO | 15/390575 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 17/5009 (20130101) G06F 17/5045 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/007 (20130101) H01L 33/10 (20130101) H01L 33/20 (20130101) H01L 33/22 (20130101) Original (OR) Class H01L 33/32 (20130101) H01L 33/62 (20130101) H01L 2933/0083 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320153 | Binder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rudolf Heinrich Binder (Tucson, Arizona); Nai-Hang Kwong (Tucson, Arizona); Paul Bryan Lundquist (Longmont, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rudolf Heinrich Binder (Tucson, Arizona); Nai-Hang Kwong (Tucson, Arizona); Paul Bryan Lundquist (Longmont, Colorado) |
| ABSTRACT | Provided herein are systems and methods for switching the generation of light emissions using charge separation in a gain medium to manipulate carrier lifetimes. For a given output pulse energy, extended carrier lifetimes may allow carrier generation powers to be reduced and/or carrier generation times to be extended. L-switching of light output from a gain medium may be combined with other switching schemes utilizing different approaches to control lasing, such as Q-switching. |
| FILED | Friday, May 15, 2015 |
| APPL NO | 14/714248 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/11 (20130101) H01S 3/0933 (20130101) H01S 3/0941 (20130101) H01S 3/1022 (20130101) H01S 5/042 (20130101) H01S 5/062 (20130101) H01S 5/0614 (20130101) H01S 5/0615 (20130101) H01S 5/34333 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320232 | Pivonka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Daniel Michael Pivonka (Palo Alto, California); Anatoly Anatolievich Yakovlev (Mountain View, California); Ada Shuk Yan Poon (Redwood City, California); Teresa H. Meng (Saratoga, California) |
| ABSTRACT | Described is a locomotive implant for usage within a predetermined magnetic field. In one embodiment magnetohydrodynamics is used to generate thrust with a plurality of electrodes. In another embodiment, asymmetric drag forces are used to generate thrust. |
| FILED | Friday, July 22, 2016 |
| APPL NO | 15/217827 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00158 (20130101) A61B 5/07 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0116 (20130101) A61M 25/0127 (20130101) A61M 31/002 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 7/345 (20130101) H02J 50/10 (20160201) Original (OR) Class H02J 50/23 (20160201) H02J 50/27 (20160201) H02J 50/80 (20160201) H02J 50/90 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320467 | Elwell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Ryan Elwell (Newfield, New Jersey); Mark Govoni (Abingdon, Maryland) |
| ABSTRACT | Various embodiments are described that relate to radio beamforming waveform transmission. Transmission can occur, for example, in three manners. The first manner is time-based where waveform transmission is staggered at the same frequency. The second manner is frequency-based where different frequencies are used at one time. This third manner is a combination of time and frequency such that simultaneous transmission occurs, but at different times different frequencies are used. |
| FILED | Tuesday, September 29, 2015 |
| APPL NO | 14/868506 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Transmission H04B 7/12 (20130101) Original (OR) Class H04B 7/068 (20130101) H04B 7/0617 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320610 | Matni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Nikolai Matni (Pasadena, California); John Comstock Doyle (Pasadena, California) |
| ABSTRACT | Data network components and frameworks for the control and optimization of network traffic using layered architectures, according to embodiments of the invention, are disclosed. In one embodiment, a data network comprises a switch, a data link, a tracking processor, and a planning processor. The planning processor is configured to generate a reference trajectory by receiving a local system state from the tracking processor, calculating a reference trajectory by solving a planning problem, and sending the reference trajectory to the tracking processor. The tracking processor is configured to track the reference trajectory by determining a set of states of the switch over a time interval, sending a local system state to the planning processor, receiving the reference trajectory from the planning processor, computing a control action by solving a tracking problem based on the reference trajectory, determining an instruction based on the control action, and sending the instruction to the switch. |
| FILED | Monday, October 17, 2016 |
| APPL NO | 15/295507 |
| ART UNIT | 2479 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/147 (20130101) H04L 41/0823 (20130101) Original (OR) Class H04L 43/0876 (20130101) H04L 45/42 (20130101) H04L 49/25 (20130101) H04L 49/552 (20130101) Wireless Communication Networks H04W 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320901 | Roy |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Radhika Roy (Howell, New Jersey) |
| ABSTRACT | Various embodiments are described that relate to network communication. In a mobile peer-to-peer ad hoc network, nodes can use a context-aware key-based distribution hash table routing algorithm to create the route scheme. This can be done among nodes that are cluster-heads while nodes that are within a cluster can use a non-context based algorithm. |
| FILED | Monday, November 23, 2015 |
| APPL NO | 14/948862 |
| ART UNIT | 2457 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/02 (20130101) H04L 45/7453 (20130101) H04L 67/1065 (20130101) Original (OR) Class Wireless Communication Networks H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10321068 | Fleizach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gregory K. Fleizach (San Diego, California); Micaela M. Wiseman (Boston, Massachusetts) |
| ABSTRACT | A method and system for automatically adjusting an iris opening in an imaging system. The method includes an iterative process that continues to adjust the camera's iris opening until an algorithm stopping condition is met. More particularly, a processor determines a brightness for the image at the current aperture setting. The processor classifies the image according to one of at least two brightness regime classifications. Based on the classifying step, the processor selects a pre-set optimal brightness parameter. The processor compares the brightness value of the image to the pre-set optimal value. The camera's iris opening is automatically adjusted based on a formula that takes into account, the current f-stop setting, the current brightness value, and the optimal brightness value. The iterative process continues until an algorithm stopping condition is met. |
| FILED | Wednesday, September 13, 2017 |
| APPL NO | 15/703837 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 9/14 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 8/42 (20130101) Pictorial Communication, e.g Television H04N 5/238 (20130101) Original (OR) Class H04N 5/2351 (20130101) H04N 5/2352 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10321557 | Brigham |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute Of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Glenn A. Brigham (Chelmsford, Massachusetts) |
| ABSTRACT | An assembly that includes a printed circuit board having an air gap, and a method of fabricating the assembly is disclosed. The assembly includes at least one air gap. This air gap is created by using a soluble material during the PCB assembly process. The soluble material can preferably be processed in accordance with traditional PCB fabrication processes. For example, other materials can be bonded to the soluble material. Additionally, the soluble material is capable of withstanding a drilling process. After the PCB assembly is complete, the soluble material is then dissolved, leaving an air gap where the soluble material once existed. This assembly may be useful in configurations where an antenna, EBG material or other electronic structure is to be disposed above the top surface of the printed circuit board. |
| FILED | Thursday, April 09, 2015 |
| APPL NO | 15/302645 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 15/0006 (20130101) H01Q 15/141 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/115 (20130101) H05K 1/165 (20130101) H05K 1/181 (20130101) H05K 1/0236 (20130101) Original (OR) Class H05K 3/4038 (20130101) H05K 3/4697 (20130101) H05K 2201/10098 (20130101) H05K 2203/308 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49165 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10315185 | Nell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon); Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon); Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Kara Nell (Eugene, Oregon); Darren W. Johnson (Eugene, Oregon); Jonathan Pittman (Richland, Washington); Wilaiwan Chouyyok (Richland, Washington); Raymond Shane Addleman (Richland, Washington); Marvin G. Warner (Richland, Washington) |
| ABSTRACT | Disclosed herein is a material comprising a functionalized solid support surface, wherein the functionalization comprises a thioalkylene linker bound to the support surface and the thioalkylene linker is coupled to a moiety derived from a ligand, wherein the ligand includes a terminal alkenyl and at least one first functional group configured to bind to at least one predetermined target species. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 15/650234 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/103 (20130101) B01J 20/3042 (20130101) Original (OR) Class B01J 2219/00596 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/11 (20130101) Acyclic or Carbocyclic Compounds C07C 323/25 (20130101) C07C 323/29 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/3839 (20130101) C07F 9/3847 (20130101) C07F 9/3865 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10315246 | Wegst et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire); WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Ulrike G. K. Wegst (Hanover, New Hampshire); Philipp Hunger (Pittsburgh, Pennsylvania); Todd Allen (Idaho Falls, Idaho) |
| ABSTRACT | A multiphase composite, formed by freeze-casting, lyophilization, and sintering, has sintered particles forming a scaffold having at least one region of aligned porosity; and a second phase formed in pores of the scaffold. In a particular embodiment, the second phase is a nuclear fuel, in another, the first phase is a nuclear fuel, and in others, both phases are nuclear fuels. In some embodiments, the first phase is a ceramic, and in other embodiments a metal such as stainless steel. In other embodiments, the second phase is a metal, and in other embodiments a ceramic. In some embodiments the second phase is positioned in a subset of pores of the scaffold, at least some additional pores being filled with a third phase. In embodiments, the second phase is also sintered. |
| FILED | Tuesday, March 04, 2014 |
| APPL NO | 14/196883 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 15/00 (20130101) Original (OR) Class B22D 25/005 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/10 (20130101) B22F 3/24 (20130101) B22F 5/10 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 43/025 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/34 (20130101) C01P 2004/50 (20130101) Nuclear Reactors G21C 3/623 (20130101) G21C 3/626 (20130101) G21C 21/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0485 (20130101) H01M 4/661 (20130101) H01M 4/801 (20130101) H01M 2004/021 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10315926 | Nakano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Jinichiro Nakano (Albany, Oregon); Anna Nakano (Albany, Oregon); James P. Bennett (Salem, Oregon) |
| ABSTRACT | Embodiments relate to methods, systems And apparatus tor generating lithium from brine. The brine is heated in a first vessel to greater than 260° C. and CO2 gas is injected mixing with the brine such that the CO2/P is greater than 18 g/atm. The brine is held at greater than 18 g/atm for longer than 20 minutes so that any impurities precipitate as solids leaving only lithium ions and chlorine ions. The brine is moved to a second vessel screening out solid precipitates leaving a brine containing only chlorine and lithium. CO2 gas is injected and mixed with the brine at 260° C. so that the CO2/P is greater than 200 g/atm. The brine is held at greater than 200 g/atm for longer than 20 minutes suppressing the chlorine as dissolved ions while lithium precipitates out as lithium carbonate. The lithium carbonate precipitate is removed from the brine solution. |
| FILED | Tuesday, October 10, 2017 |
| APPL NO | 15/728784 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 15/08 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/80 (20130101) Alloys C22C 24/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316060 | Tovar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | John D. Tovar (Baltimore, Maryland); Howard E. Katz (Owings Mills, Maryland); Herdeline Ann M. Ardona (Baltimore, Maryland); Allix Sanders (Baltimore, Maryland); Kalpana Besar (Baltimore, Maryland) |
| ABSTRACT | Nanostructures comprising Π-conjugated peptides for energy migration in aqueous environments are disclosed. Conductive material comprising these nanostructures, and supramolecular assemblies comprising covalently-bound electron donor-acceptor chromophores for photoinduced electron transfer also are disclosed. |
| FILED | Tuesday, November 24, 2015 |
| APPL NO | 14/950603 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 5/06026 (20130101) C07K 5/06052 (20130101) C07K 7/06 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/49 (20130101) H01L 29/0665 (20130101) H01L 51/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316068 | Mukhopadhyay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aindrila Mukhopadhyay (Oakland, California); Amanda Reider Apel (Alameda, California); Mario Ouellet (Castro Valley, California); Jay D. Keasling (Berkeley, California) |
| ABSTRACT | This disclosure provides methods and compositions related to microbial gene expression. In one aspect, a synthetic polypeptide having a xylose import activity. |
| FILED | Thursday, July 14, 2016 |
| APPL NO | 15/210834 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/395 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316180 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Zhilin Yu (Evanston, Illinois); Samuel I. Stupp (Chicago, Illinois) |
| ABSTRACT | Provided herein are compositions comprising covalent and supramolecular polymers, and methods of preparation and use thereof. |
| FILED | Wednesday, September 28, 2016 |
| APPL NO | 15/278610 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 12/08 (20130101) C08G 12/46 (20130101) C08G 69/10 (20130101) C08G 69/36 (20130101) Compositions of Macromolecular Compounds C08L 61/22 (20130101) Original (OR) Class C08L 61/22 (20130101) C08L 61/22 (20130101) C08L 77/04 (20130101) C08L 77/04 (20130101) C08L 77/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316336 | Survase et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | API Intellectual Property Holdings, LLC (Minnetrista, Minnesota) |
| ASSIGNEE(S) | API Intellectual Property Holdings, LLC (Atlanta, Georgia) |
| INVENTOR(S) | Shrikant Survase (Thomaston, Georgia); Ryan Zebroski (Fayetteville, Georgia); Georgios Adamos (Thomaston, Georgia); Vesa Pylkkanen (Atlanta, Georgia) |
| ABSTRACT | This invention provides optimized fermentation of cellulosic and hemicellulosic sugars. Biomass-derived hemicellulosic and cellulosic sugars are independently conditioned and separately fermented, utilizing reuse and recycle of microorganisms, metabolic intermediates, and nutrients. Conditioned sugars can be fermented in separate vessels, where excess cells from glucose fermentation are conveyed to hemicellulose sugar fermentation along with raffinate from solvent recovery, to enhance productivity and product yield. Some variations provide a method of fermenting C5 and C6 sugars to fermentation products, the method comprising: fermenting a C6-rich sugar feed to a first fermentation product; fermenting a C5-rich sugar feed to a second fermentation product; removing microorganism cells from the first fermentor, to maintain a cell concentration within a selected range; conveying microorganism cells to a second fermentor; and removing microorganism cells from the second fermentor, to maintain a microorganism cell concentration that is greater than that in the C6-rich fermentor. |
| FILED | Thursday, May 25, 2017 |
| APPL NO | 15/605930 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) C12P 7/10 (20130101) Original (OR) Class C12P 7/16 (20130101) C12P 7/28 (20130101) C12P 7/52 (20130101) C12P 7/54 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2201/00 (20130101) C12P 2203/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316343 | Quinlan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes, Inc. (Davis, California); Novozymes North America, Inc. (Franklinton, North Carolina) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California); Novozymes North America, Inc. (Franklinton, North Carolina) |
| INVENTOR(S) | Jason Quinlan (Woodland, California); Feng Xu (Davis, California); Matt Sweeney (Sacramento, California); Don Higgins (Franklinton, North Carolina); Hui Xu (Wake Forest, North Carolina) |
| ABSTRACT | The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and a liquor. The present invention also relates to methods of using the compositions. |
| FILED | Tuesday, June 07, 2016 |
| APPL NO | 15/175645 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/37 (20130101) C07K 14/38 (20130101) C07K 14/385 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) C12N 9/2437 (20130101) C12N 9/2445 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/002 (20130101) C12P 5/02 (20130101) C12P 5/026 (20130101) C12P 7/10 (20130101) C12P 7/26 (20130101) C12P 7/28 (20130101) C12P 7/40 (20130101) C12P 13/04 (20130101) C12P 19/02 (20130101) C12P 19/12 (20130101) C12P 19/14 (20130101) Original (OR) Class C12P 2201/00 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 302/01004 (20130101) C12Y 302/01021 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316344 | Berka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Randy Berka (Davis, California); Joel Cherry (Winters, California) |
| ABSTRACT | The present invention relates to methods for converting plant cell wall polysaccharides into one or more products, comprising: treating the plant cell wall polysaccharides with an effective amount of a spent whole fermentation broth of a recombinant microorganism, wherein the recombinant microorganism expresses one or more heterologous genes encoding enzymes which degrade or convert the plant cell wall polysaccharides into the one or more products. The present invention also relates to methods for producing an organic substance, comprising: (a) saccharifying plant cell wall polysaccharides with an effective amount of a spent whole fermentation broth of a recombinant microorganism, wherein the recombinant microorganism expresses one or more heterologous genes encoding enzymes which degrade or convert the plant cell wall polysaccharides into saccharified material; (b) fermenting the saccharified material of step (a) with one or more fermenting microoganisms; and (c) recovering the organic substance from the fermentation. |
| FILED | Wednesday, June 15, 2016 |
| APPL NO | 15/183474 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/023 (20130101) C12P 7/00 (20130101) C12P 7/02 (20130101) C12P 7/04 (20130101) C12P 7/06 (20130101) C12P 7/10 (20130101) C12P 7/16 (20130101) C12P 7/18 (20130101) C12P 7/20 (20130101) C12P 7/26 (20130101) C12P 7/28 (20130101) C12P 7/40 (20130101) C12P 13/04 (20130101) C12P 17/04 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) Y02E 50/16 (20130101) Y02E 50/17 (20130101) Y02E 50/343 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316737 | Mendler, III |
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| FUNDED BY |
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| APPLICANT(S) | Edward Charles Mendler, III (Mill Valley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edward Charles Mendler, III (Mill Valley, California) |
| ABSTRACT | According to the present invention, a rotary blower or supercharger includes a recirculation loop for readmitting pressurized outlet gas back into the rotor chambers, and cooling means for cooling the pressurized outlet gas before it is readmitted into the rotor chambers, thereby providing a supercharger having a lower operating temperature and a higher operating pressure capability. In the preferred embodiment of the present invention, a supercharger includes a housing assembly defining first and second transversely overlapping cylindrical chambers. The housing defines an inlet port for the inflow of an inlet gas, and an outlet port for the outflow of the outlet gas. The supercharger further has first and second meshed, lobed rotors respectively disposed in the chambers for counter rotation about axes substantially coincident with the chamber axes. According to the present invention, the housing further includes a recirculation port and a recirculation flow path for recirculation of a portion of outlet gas flowing out of the outlet port back into cylindrical chamber. The recirculation flow path further including cooling means for cooling of at least a portion of the outlet gas, thereby providing a cooler operating supercharger. |
| FILED | Friday, April 10, 2015 |
| APPL NO | 15/330526 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cooling of Machines or Engines in General; Cooling of Internal-combustion Engines F01P 2060/02 (20130101) Internal-combustion Piston Engines; Combustion Engines in General F02B 29/0475 (20130101) F02B 33/38 (20130101) Original (OR) Class F02B 39/16 (20130101) F02B 2039/164 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/146 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317060 | Nimma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sridhar Reddy Nimma (Cumming, Georgia); Matthew A. Davis (Orange, California) |
| ASSIGNEE(S) | EATON INTELLIGENT POWER LIMITED (Dublin, Ireland) |
| INVENTOR(S) | Sridhar Reddy Nimma (Cumming, Georgia); Matthew A. Davis (Orange, California) |
| ABSTRACT | A lighting fixture can comprise a substantially flat sheet of metal supporting a circuit that comprises one or more light emitting diodes with one or more associated optics for manipulating emitted light. The circuit can be attached to, mounted next to, or integrated with the sheet of metal. In some examples, a layer of dielectric material adheres to the sheet of metal, and circuit elements adhere to the layer of dielectric material. Such circuit elements may comprise electrical traces, light emitting diodes, and/or a light emitting diode driver. The sheet of metal can provide a substrate for the circuit or a support for a freestanding circuit board that may be rigid or flexible. |
| FILED | Thursday, August 27, 2015 |
| APPL NO | 14/837597 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Non-portable Lighting Devices; Systems Thereof; Vehicle Lighting Devices Specially Adapted for Vehicle Exteriors F21S 8/086 (20130101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 5/007 (20130101) F21V 19/003 (20130101) F21V 21/116 (20130101) F21V 23/005 (20130101) Original (OR) Class F21V 23/008 (20130101) F21V 23/0464 (20130101) F21V 23/0471 (20130101) F21V 31/005 (20130101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to Uses or Applications of Lighting Devices or Systems F21W 2131/103 (20130101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2105/10 (20160801) F21Y 2115/10 (20160801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317300 | Elizondo-Decanini |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Juan M. Elizondo-Decanini (Albuquerque, New Mexico) |
| ABSTRACT | Described herein is an apparatus that includes a varactor and an inductor to form a resonant circuit that oscillates at a resonant frequency. The resonant frequency is a function of a pressure of a gas within an aperture of the varactor. In some embodiment, the varactor includes a first layer of p-type material, a first layer of n-type material, and a first np junction formed between the layer of p-type material and the layer of n-type material. The aperture extends at least partially through the layer of p-type material, at least partially through the layer of n-type material, and entirely through the np junction. |
| FILED | Friday, September 30, 2016 |
| APPL NO | 15/281909 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/12 (20130101) G01L 9/0098 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/93 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10317364 — Method and apparatus for ion mobility separations utilizing alternating current waveforms
| US 10317364 | Garimella et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Venkata B S Garimella (Richland, Washington); Ahmed M. Hamid (Richland, Washington); Yehia M. Ibrahim (West Richland, Washington); Richard D. Smith (Richland, Washington) |
| ABSTRACT | Methods and apparatuses for ion manipulations, including ion trapping, transfer, and mobility separations, using traveling waves (TW) formed by continuous alternating current (AC) are disclosed. An apparatus for ion manipulation includes a surface to which are coupled a first plurality of continuous electrodes and a second plurality of segmented electrodes. The second plurality of segmented electrodes is arranged in longitudinal sets between or adjacent to the first plurality of electrodes. An RF voltage applied to adjacent electrodes of the first plurality of electrodes is phase shifted by approximately 180° to confine ions within the apparatus. An AC voltage waveform applied to adjacent electrodes within a longitudinal set of the second plurality of segmented electrodes is phase shifted on the adjacent electrodes by 1°-359° to move ions longitudinally through the apparatus for separation. |
| FILED | Monday, August 15, 2016 |
| APPL NO | 15/774837 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/624 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/26 (20130101) H01J 49/0027 (20130101) H01J 49/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317539 | Zorn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
| ASSIGNEE(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
| INVENTOR(S) | Carl Zorn (Yorktown, Virginia); Andrew Weisenberger (Yorktown, Virginia); Wenze Xi (Ellicott City, Maryland) |
| ABSTRACT | A radiation monitor apparatus and method based on wavelength-dependent optical absorption in fused silica optical fibers. The radiation monitor uses the radiation induced optical changes in fused silica optical fibers as a way to quantify and differentiate the large doses of radiation from high energy photons and neutrons as well as providing a method to extend the sensitivity over a large dynamic range of doses from 103 to beyond 106 rads. The radiation monitor enables dynamic monitoring of highly ionizing radiation environments. The radiation monitor reduces sensitivity saturation at high dose levels, provides increased sensitivity over a large dynamic range of doses, and enables differentiation between high energy photon and neutron contributions or poor signal to noise. |
| FILED | Friday, April 13, 2018 |
| APPL NO | 15/952841 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/02 (20130101) G01T 1/06 (20130101) Original (OR) Class G01T 3/00 (20130101) G01T 3/08 (20130101) G01T 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317774 | Muir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Ryan D Muir (Livermore, California); John E Heebner (San Ramon, California) |
| ABSTRACT | Single-shot transient optical signals are recorded in a time regime of picoseconds to nanosecond. An auxiliary pump beam is crossed through the signal to sample a diagonal ‘slice’ of space-time, analogous to a rolling shutter. The slice is then imaged onto an ordinary camera, where the recorded spatial trace is a direct representation of the time content of the signal. The pump samples the signal by optically exciting carriers that modify the refractive index in a conventional semiconductor wafer. Through use of birefringent retarders surrounding the wafer, the integrating response of the rapidly excited but persistent carriers is differentiated by probing with two polarization-encoded time-staggered signal replicas that are recombined to interfere destructively. |
| FILED | Thursday, May 11, 2017 |
| APPL NO | 15/593256 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3517 (20130101) Original (OR) Class G02F 1/3556 (20130101) G02F 2201/20 (20130101) G02F 2203/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317852 | Spooner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jeffrey T. Spooner (Albuquerque, New Mexico) |
| ABSTRACT | The various technologies presented herein relate to utilizing predictive guidance during one or more phases of a trajectory flown by an interceptor during interception with a target. The trajectory of the interceptor comprises an initial phase, a predictive phase, and a final phase. The initial phase includes the launching of the interceptor and can be unguided. The predictive phase directs the interceptor towards the target, wherein the predictive phase utilizes predictive guidance to control the trajectory of the interceptor based upon a predicted location of the target relative to the current locations of the target and the interceptor. During the predictive phase, a motor(s) can be cycled on and off, causing a period(s) where the interceptor is being propelled by the ignited motor, and a period(s) where the interceptor is propelled by its own momentum after cessation of power from the motor, e.g., unpowered flight. |
| FILED | Thursday, October 29, 2015 |
| APPL NO | 14/927118 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 15/01 (20130101) F42B 15/10 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/026 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317970 | Peng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Qiuyu Peng (Pasadena, California); Steven H. Low (La Canada, California) |
| ABSTRACT | Node controllers and power distribution networks in accordance with embodiments of the invention enable distributed power control on an unbalanced network. One embodiment includes a node controller including a distributed power control application; a plurality of node operating parameters describing the operating parameter of a node in an unbalanced network; wherein the processor is configured by the distributed power control application to: send node operating parameters to nodes in the set of at least one node; receive operating parameters from the nodes in the set of at least one node; calculate a plurality of updated node operating parameters using an iterative process to determine updated node operating parameters using the node operating parameters that describe the operating parameters of the node, and the operating parameters of the set of at least one node, where each iteration in the iterative process involves evaluation of a subproblem; and adjust node operating parameters. |
| FILED | Thursday, April 21, 2016 |
| APPL NO | 15/135249 |
| ART UNIT | 2446 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 1/266 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 12/10 (20130101) H04L 41/0816 (20130101) H04L 41/0833 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 40/162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318363 | Sadowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Greg Sadowski (Cambridge, Massachusetts); Steven E. Raasch (Worcester, Massachusetts); Shomit N. Das (Austin, Texas); Wayne Burleson (Shutesbury, Massachusetts) |
| ABSTRACT | A system and method for managing operating parameters within a system for optimal power and reliability are described. A device includes a functional unit and a corresponding reliability evaluator. The functional unit provides reliability information to one or more reliability monitors, which translate the information to reliability values. The reliability evaluator determines an overall reliability level for the system based on the reliability values. The reliability monitor compares the actual usage values and the expected usage values. When system has maintained a relatively high level of reliability for a given time interval, the reliability evaluator sends an indication to update operating parameters to reduce reliability of the system, which also reduces power consumption for the system. |
| FILED | Friday, October 28, 2016 |
| APPL NO | 15/338172 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/008 (20130101) Original (OR) Class G06F 11/3058 (20130101) G06F 11/3452 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/34 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318444 | Michelogiannakis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgios Michelogiannakis (Berkeley, California); John Shalf (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Georgios Michelogiannakis (Berkeley, California); John Shalf (Oakland, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus for collective memory transfers. A control unit may be configured to coordinate a transfer of data between a memory and processor cores. For a read data transfer operation, the control unit may receive a trigger packet identifying a read data transfer operation and identifying a first plurality of data lines based on data values included in the trigger packet. The control unit may read the first plurality of data lines from the memory sequentially and send a second plurality of data lines to the processor cores. For a write data transfer operation, the control unit may send a request for at least one data line to a plurality of processor cores, may receive and reorder the requested data lines, and may write the data lines to a memory. The control unit may determine a mapping between processor cores and the memory. |
| FILED | Thursday, April 10, 2014 |
| APPL NO | 14/250085 |
| ART UNIT | 2139 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0223 (20130101) G06F 13/1626 (20130101) Original (OR) Class G06F 13/1652 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/13 (20180101) Y02D 10/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318880 | Pereverzev |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Sergey Pereverzev (San Ramon, California) |
| ABSTRACT | Materials, devices, methods of use and fabrication thereof are disclosed. The materials are particularly well suited for application in superconducting devices and quantum computing, due to ability to avoid undesirable effects from inherent noise and decoherence. The materials are formed from select isotopes having zero nuclear spin into a single crystal-phase film or layer of thickness depending on the desired application of the resulting device. The film/layer may be suspended or disposed on a substrate. The isotopes may be enriched from naturally-occurring sources of isotopically mixed elemental material(s). The single crystal is preferably devoid of structural defects such as grain boundaries, inclusions, impurities and lattice vacancies. Device configurations may be formed from the layer according to a predetermined pattern using lithographic and/or milling techniques. An optional protective layer may be deposited on some or all of the device to avoid formation of oxides and/or patinas on surfaces of the device. |
| FILED | Wednesday, May 13, 2015 |
| APPL NO | 14/711718 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 13/00 (20130101) C01B 19/02 (20130101) C01B 32/00 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/40 (20130101) Alloys C22C 5/04 (20130101) C22C 27/04 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/02 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/12 (20130101) H01L 39/223 (20130101) H01L 39/2493 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10319461 | Kwon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kon-Woo Kwon (Hillsboro, Oregon); Vivek Kozhikkottu (Hillsboro, Oregon); Dinesh Somasekhar (Portland, Oregon) |
| ABSTRACT | Embodiments are generally directed to a low-overhead mechanism to detect address faults in ECC-protected memories. An embodiment of an apparatus includes a memory array; an error correction code (ECC) encoder for the memory array to encode ECC values based on a data value and a respective address value for the data value; and an ECC decoder for the memory array to decode ECC values that are based on data values and respective addresses for the data values; wherein the apparatus is to detect and correct an error in an address value based on an ECC value, address value, and data value stored in the memory. |
| FILED | Wednesday, June 29, 2016 |
| APPL NO | 15/197590 |
| ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1048 (20130101) G06F 11/1068 (20130101) Static Stores G11C 29/024 (20130101) G11C 29/42 (20130101) G11C 29/52 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10319489 | Ren et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Zhifeng Ren (Houston, Texas); Chuanfei Guo (Houston, Texas); Yuan Liu (Houston, Texas) |
| ABSTRACT | Systems and methods of fabricating electrodes, including thin metallic films, include depositing a first metallic layer on a substrate and passivating the deposited layer. The processes of deposition and passivation may be done sequentially. In some embodiments, a plurality of substrates may be coated with a metallic layer and further processed at a later time, including passivation and disposal of additional layers as discussed herein. |
| FILED | Wednesday, February 10, 2016 |
| APPL NO | 15/547033 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Photosensitive Materials for Photographic Purposes; Photographic Processes, e.g Cine, X-RAY, Colour, Stereo-photographic Processes; Auxiliary Processes in Photography G03C 1/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/16 (20130101) Original (OR) Class H01B 1/22 (20130101) H01B 1/023 (20130101) H01B 1/026 (20130101) H01B 13/0036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10319871 | Gershon et al. |
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| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Talia S. Gershon (White Plains, New York); Supratik Guha (Chicago, Illinois); Oki Gunawan (Westwood, New Jersey); Richard A. Haight (Mahopac, New York); Yun Seog Lee (White Plains, New York) |
| ABSTRACT | Photovoltaic devices based on an Ag2ZnSn(S,Se)4 (AZTSSe) absorber and techniques for formation thereof are provided. In one aspect, a method for forming a photovoltaic device includes the steps of: coating a substrate with a conductive layer; contacting the substrate with an Ag source, a Zn source, a Sn source, and at least one of a S source and a Se source under conditions sufficient to form an absorber layer on the conductive layer having Ag, Zn, Sn, and at least one of S and Se; and annealing the absorber layer. Methods of doping the AZTSSe are provided. A photovoltaic device is also provided. |
| FILED | Thursday, July 05, 2018 |
| APPL NO | 16/028249 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0256 (20130101) H01L 21/0262 (20130101) H01L 21/02557 (20130101) H01L 21/02568 (20130101) H01L 21/02579 (20130101) H01L 31/07 (20130101) H01L 31/072 (20130101) Original (OR) Class H01L 31/0326 (20130101) H01L 31/0327 (20130101) H01L 31/0392 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10319989 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Xinwei Chen (Cambridge, Massachusetts); Jiayan Luo (Cambridge, Massachusetts); Yet-Ming Chiang (Weston, Massachusetts) |
| ABSTRACT | Embodiments described herein relate generally to lithium sulfur batteries and methods of producing the same. As described herein, preventing coarsening of sulfur during the well-known melt-diffusion processing of cathodes allows a high areal capacity of 10.7 mAh/cm2 at current density of 3.4 mA/cm2 (C-rate of 1/5 h−1). The addition of a lithium salt, such as LiTFSI, prior to melt-diffusion can prevent coarsening of molten sulfur and allows creation of a sulfur electrode with a high concentration of triple-phase junctions for electrochemical reaction. In some embodiments, approximately 60-70% utilization of the theoretical capacity of sulfur is reached at a high loading (e.g., greater than 7.5 mg S/cm2). The electrodes are prepared in lean-electrolyte environment of 3 mlelectrolyte/gsulfur (˜70 vol % of electrolyte in the electrode) for high areal capacity in Li—S batteries. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 15/905017 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/136 (20130101) H01M 4/0483 (20130101) H01M 4/625 (20130101) H01M 4/1397 (20130101) Original (OR) Class H01M 10/052 (20130101) H01M 2300/0028 (20130101) H01M 2300/0065 (20130101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320000 | Naskar et al. |
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| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Amit K. Naskar (Knoxville, Tennessee); Mariappan Parans Paranthaman (Knoxville, Tennessee) |
| ABSTRACT | A method of recovering carbon black includes the step of providing a carbonaceous source material containing carbon black. The carbonaceous source material is contacted with a sulfonation bath to produce a sulfonated material. The sulfonated material is pyrolyzed to produce a carbon black containing product comprising a glassy carbon matrix phase having carbon black dispersed therein. The pyrolysis can be conducted at a temperature from 1100° C. to 1490° C. A method of making a battery electrode and a lithium ion or sodium ion battery is also disclosed. |
| FILED | Monday, February 29, 2016 |
| APPL NO | 15/056184 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/04 (20130101) C01P 2006/12 (20130101) C01P 2006/40 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/48 (20130101) C09C 1/482 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/0471 (20130101) H01M 4/587 (20130101) Original (OR) Class H01M 4/1393 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320004 | Kongkanand et al. |
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| FUNDED BY |
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| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Anusorn Kongkanand (Rochester Hills, Michigan); Michael K. Carpenter (Troy, Michigan) |
| ABSTRACT | A method of making a fuel cell including the following steps: comprising: (a) mixing carbon nanotubes (CNT) with an initial dispersion, wherein the initial dispersion includes an ionomer; (b) heating and stirring the initial dispersion to form a CNT-ionomer composite suspension; (c) after forming the CNT-ionomer composite suspension, mixing the CNT-ionomer composite suspension with an electrode catalyst solution to form an electrode ink, wherein the electrode catalyst solution includes a carbon black powder and a catalyst supported by the carbon black powder; and (d) coating a proton exchange membrane with the electrode ink to form the fuel cell electrode. |
| FILED | Friday, May 12, 2017 |
| APPL NO | 15/593383 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 39/20 (20130101) B01J 47/12 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/225 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/881 (20130101) H01M 4/926 (20130101) H01M 4/8663 (20130101) H01M 4/8673 (20130101) H01M 4/8828 (20130101) H01M 4/8892 (20130101) Original (OR) Class H01M 8/1004 (20130101) H01M 8/1032 (20130101) H01M 8/1039 (20130101) H01M 2008/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320028 | Sava Gallis et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Dorina F. Sava Gallis (Albuquerque, New Mexico); Harry D. Pratt (Albuquerque, New Mexico); Travis Mark Anderson (Albuquerque, New Mexico); Nicholas Hudak (Washington, District of Columbia) |
| ABSTRACT | A sodium ion battery comprises a cathode having a porous redox active metal-organic framework material. The battery can be an organic electrolyte sodium ion battery wherein the electrolyte comprises a sodium salt dissolved in an organic solvent or mixture of organic solvents. Alternatively, the battery can comprise an aqueous sodium ion battery wherein the electrolyte comprises a sodium salt dissolved in an aqueous solvent. Battery performance is especially related to electrolyte and binder selection. |
| FILED | Monday, July 31, 2017 |
| APPL NO | 15/664507 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 13/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/025 (20130101) Polysaccharides; Derivatives Thereof C08B 11/12 (20130101) Compositions of Macromolecular Compounds C08L 1/286 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/022 (20130101) H01M 2/0222 (20130101) H01M 4/381 (20130101) H01M 4/382 (20130101) H01M 4/623 (20130101) H01M 10/0564 (20130101) Original (OR) Class H01M 10/0565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10321564 | Takken et al. |
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| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Todd E. Takken (Brewster, New York); Xin Zhang (Yorktown Heights, New York); Yuan Yao (Tarrytown, New York); Andrew Ferencz (Southborough, Massachusetts) |
| ABSTRACT | A printed circuit board (PCB) and PCB assembly. The PCB is formed of a laminate substrate of at least two layers of a non-conductive material forming at least one peripheral end face (PEF) surface separating top and bottom PCB surfaces. Embedded conductive wiring at one or more multiple layers carry energy to or from PCB surface mounted devices. The conductive wiring provides multiple conductive wire ends exposed at multiple locations along the PEF. A conductive contact structure is formed at the PEF surface to connect with one or more of the exposed conductive wire ends. One or more conductive pins are attached to the conductive contact at the PEF and are configured to mount the PCB on, and in a vertical and perpendicular orientation or a coplanar orientation relative to, a surface of a second PCB surface. The conductive pins provide one or more of: an electrical, thermal and/or mechanical contact. |
| FILED | Thursday, November 09, 2017 |
| APPL NO | 15/808786 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/113 (20130101) H05K 1/0203 (20130101) H05K 1/0298 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10314503 | Prerau et al. |
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| FUNDED BY |
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| APPLICANT(S) | Michael J. Prerau (Somerville, Massachusetts); Patrick L. Purdon (Somerville, Massachusetts); Uri Eden (Somerville, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Michael J. Prerau (Somerville, Massachusetts); Patrick L. Purdon (Somerville, Massachusetts); Uri Eden (Somerville, Massachusetts) |
| ABSTRACT | Systems and methods for tracking dynamic structure in physiological data are provided. In some aspects, the method includes providing physiological data, including electroencephalogram (“EEG”) data, acquired from a subject and assembling a time-frequency representation of signals from the physiological data. The method also includes generating a dynamic model of at least one non-stationary spectral feature, such as at least one non-stationary spectral peak, using the time-frequency representation and a user indication, and applying a dynamic model of at least one non-stationary spectral feature in a parameter estimation algorithm to compute concurrent estimates of spectral parameters describing the at least one non-stationary spectral feature. The method also includes tracking the spectral parameters of the at least one spectral feature over time. |
| FILED | Friday, June 27, 2014 |
| APPL NO | 14/900805 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/048 (20130101) A61B 5/0402 (20130101) A61B 5/0488 (20130101) A61B 5/0496 (20130101) A61B 5/0533 (20130101) A61B 5/725 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/4806 (20130101) A61B 5/4821 (20130101) A61B 5/4839 (20130101) A61B 5/7253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314938 | Kaplan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Ballou Hall, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Ung-Jin Kim (Daejeon, South Korea); Jaehyung Park (Decatur, Georgia); Hyoung-Joon Jin (Seoul, South Korea) |
| ABSTRACT | The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels. |
| FILED | Thursday, February 16, 2017 |
| APPL NO | 15/434484 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/38 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 27/3604 (20130101) A61L 2430/02 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/003 (20130101) B29C 39/203 (20130101) B29C 55/005 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 7/01 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2089/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2007/00 (20130101) B29L 2009/00 (20130101) Peptides C07K 14/43536 (20130101) C07K 14/43586 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/07 (20130101) C08J 3/075 (20130101) C08J 5/18 (20130101) C08J 9/26 (20130101) C08J 9/28 (20130101) C08J 9/0061 (20130101) C08J 2201/0444 (20130101) C08J 2201/0504 (20130101) C08J 2205/022 (20130101) C08J 2389/00 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249921 (20150401) Y10T 442/10 (20150401) Y10T 442/60 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314945 | Puskas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Judit E. Puskas (Akron, Ohio); Alejandra Alvarez Albarran (Allison Park, Pennsylvania); Emily Q. Rosenthal-Kim (Dublin, Ohio) |
| ASSIGNEE(S) | THE UNIVERSITY OF AKRON (Akron, Ohio) |
| INVENTOR(S) | Judit E. Puskas (Akron, Ohio); Alejandra Alvarez Albarran (Allison Park, Pennsylvania); Emily Q. Rosenthal-Kim (Dublin, Ohio) |
| ABSTRACT | A polymer composite includes a functionalized polyisobutylene and an additional polyisobutylene-containing material. The functionalized polyisobutylene includes an α-lipoic acid functional group. A method for producing the polymer composite includes providing the additional polyisobutylene-containing material as a substrate having a surface, and coating the surface of the substrate with the functionalized polyisobutylene. A method for producing a coated substrate including the polymer composite includes providing a polymer combination including the functionalized polyisobutylene and the additional polyisobutylene-containing material, and depositing the polymer combination on to a substrate to thereby form the coated substrate. |
| FILED | Tuesday, April 18, 2017 |
| APPL NO | 15/490080 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/48 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 29/085 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/10 (20130101) A61L 2300/606 (20130101) A61L 2420/02 (20130101) A61L 2420/04 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) B05D 1/04 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/14 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/02 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/047 (20130101) C08J 2323/22 (20130101) C08J 2423/26 (20130101) Compositions of Macromolecular Compounds C08L 23/20 (20130101) C08L 23/20 (20130101) C08L 23/20 (20130101) C08L 53/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 153/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314950 | Mayes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Sarah Mayes (Austin, Texas); Christine E. Schmidt (Gainesville, Florida) |
| ABSTRACT | A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components. |
| FILED | Tuesday, May 16, 2017 |
| APPL NO | 15/596685 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) A61K 31/195 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/16 (20130101) A61L 31/041 (20130101) Original (OR) Class A61L 31/041 (20130101) A61L 31/041 (20130101) A61L 31/145 (20130101) A61L 31/148 (20130101) A61L 2300/43 (20130101) A61L 2300/62 (20130101) A61L 2300/414 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10315131 | Jarvis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida) |
| INVENTOR(S) | Jacqueline M. Jarvis (Tallahassee, Florida); Ryan P. Rodgers (Tallahassee, Florida); Winston K. Robbins (Brunswick, Maine) |
| ABSTRACT | A method for preparing a crude oil solution for analysis, including adding water to a porous adsorbent to obtain a supported water substrate, having a plurality of water monolayers disposed on the porous adsorbent. The method further includes exposing the crude oil solution to the supported water substrate for a period of time; separating the supported water substrate from the crude oil solution; washing the supported water substrate with a water immiscible solvent to remove at least one hydrocarbon; displacing water from the plurality of water monolayers and the at least one interfacially active compound from the porous adsorbent with an alcohol and a co-solvent to obtain a displaced phase. The displaced phase can include the water, the at least one interfacially active compound, the alcohol, and the co-solvent. Finally, the method can include drying the displaced phase to isolate the at least one interfacially active compound. |
| FILED | Tuesday, October 22, 2013 |
| APPL NO | 14/060268 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/08 (20130101) B01D 15/265 (20130101) Original (OR) Class B01D 39/00 (20130101) B01D 39/02 (20130101) B01D 39/06 (20130101) B01D 39/2006 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/02 (20130101) B01J 20/10 (20130101) B01J 20/103 (20130101) B01J 20/0251 (20130101) B01J 20/28057 (20130101) B01J 20/28064 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/28 (20130101) C02F 1/42 (20130101) C02F 1/281 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/32 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/2823 (20130101) G01N 33/2835 (20130101) G01N 2013/0233 (20130101) G01N 2013/0275 (20130101) G01N 2030/486 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10315169 | Hoek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eric M. V. Hoek (Pacific Palisades, California); Richard B. Kaner (Pacific Palisades, California); Brian T. McVerry (Los Angeles, California) |
| ABSTRACT | Disclosed are fouling resistant filtration membranes comprising a polymeric thin-film membrane comprising a surface. Also disclosed are methods of modifying thin-film filtration membranes, thereby improving, for example, the anti-fouling properties of the membranes. Also disclosed are methods of purifying water using the disclosed membranes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 15/581783 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/08 (20130101) B01D 61/025 (20130101) B01D 65/08 (20130101) B01D 67/0088 (20130101) B01D 67/0093 (20130101) B01D 69/02 (20130101) B01D 69/08 (20130101) B01D 71/56 (20130101) B01D 71/76 (20130101) B01D 71/78 (20130101) Original (OR) Class B01D 2323/36 (20130101) B01D 2323/345 (20130101) B01D 2325/48 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/441 (20130101) C02F 2103/08 (20130101) Acyclic or Carbocyclic Compounds C07C 247/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10315275 | Vadali et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Venkata Madhukanth Vadali (Madison, Wisconsin); Chao Ma (Madison, Wisconsin); Neil Arthur Duffie (Madison, Wisconsin); Xiaochun Li (Madison, Wisconsin); Frank Ewald Pfefferkorn (Madison, Wisconsin) |
| ABSTRACT | Surface asperities, such as roughness characteristics, are reduced or otherwise mitigated via the control of surface regions including the asperities in different regimes. In accordance with various embodiments, the height of both high-frequency and low-frequency surface asperities is reduced by controlling characteristics of a surface region under a first regime to flow material from the surface asperities. A second regime is implemented to reduce a height of high-frequency surface asperities in the surface region by controlling characteristics of the surface region under a second regime to flow material that is predominantly from the high-frequency surface asperities, the controlled characteristics in the second regime being different than the controlled characteristics in the first regime. Such aspects may include, for example, controlling melt pools in each regime via energy pulses, to respectively mitigate/reduce the asperities. |
| FILED | Thursday, January 24, 2013 |
| APPL NO | 13/749426 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/354 (20151001) Original (OR) Class B23K 26/3576 (20180801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10315967 | Michalsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (Manhattan, Kansas) |
| ASSIGNEE(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| INVENTOR(S) | Ronald Michalsky (Zurich, Switzerland); Peter Pfromm (Manhattan, Kansas) |
| ABSTRACT | Reactant materials for use in the synthesis of compounds comprising a non-metal and hydrogen, and methods of making and using the same are provided. The reactant materials generally comprise first and second non-metals, metals, a cation, and a transition metal, and can be formed and used in reactions occurring at relatively low-pressure conditions using heat energy that can be supplied via solar radiation. In particular, the reactant materials can be used in the synthesis of ammonia and various hydrocarbon compounds using air, water, and sunlight. |
| FILED | Monday, November 25, 2013 |
| APPL NO | 14/647209 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/127 (20130101) B01J 38/04 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/06 (20130101) C01B 3/025 (20130101) C01B 21/16 (20130101) C01B 21/0602 (20130101) C01B 21/0637 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/026 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/54 (20130101) Acyclic or Carbocyclic Compounds C07C 1/10 (20130101) C07C 1/10 (20130101) C07C 1/10 (20130101) C07C 1/32 (20130101) Original (OR) Class C07C 1/321 (20130101) C07C 1/325 (20130101) C07C 1/328 (20130101) C07C 9/04 (20130101) C07C 11/24 (20130101) C07C 29/1518 (20130101) C07C 29/1518 (20130101) C07C 31/04 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/36 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/582 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316060 | Tovar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | John D. Tovar (Baltimore, Maryland); Howard E. Katz (Owings Mills, Maryland); Herdeline Ann M. Ardona (Baltimore, Maryland); Allix Sanders (Baltimore, Maryland); Kalpana Besar (Baltimore, Maryland) |
| ABSTRACT | Nanostructures comprising Π-conjugated peptides for energy migration in aqueous environments are disclosed. Conductive material comprising these nanostructures, and supramolecular assemblies comprising covalently-bound electron donor-acceptor chromophores for photoinduced electron transfer also are disclosed. |
| FILED | Tuesday, November 24, 2015 |
| APPL NO | 14/950603 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 5/06026 (20130101) C07K 5/06052 (20130101) C07K 7/06 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/49 (20130101) H01L 29/0665 (20130101) H01L 51/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316180 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Zhilin Yu (Evanston, Illinois); Samuel I. Stupp (Chicago, Illinois) |
| ABSTRACT | Provided herein are compositions comprising covalent and supramolecular polymers, and methods of preparation and use thereof. |
| FILED | Wednesday, September 28, 2016 |
| APPL NO | 15/278610 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 12/08 (20130101) C08G 12/46 (20130101) C08G 69/10 (20130101) C08G 69/36 (20130101) Compositions of Macromolecular Compounds C08L 61/22 (20130101) Original (OR) Class C08L 61/22 (20130101) C08L 61/22 (20130101) C08L 77/04 (20130101) C08L 77/04 (20130101) C08L 77/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316348 | Goluch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Edgar D. Goluch (Somerville, Massachusetts); Hunter J. Sismaet (Boston, Massachusetts); Thaddaeus A. Webster (Exeter, New Hampshire) |
| ABSTRACT | Methods and devices for monitoring the viability of a biofilm comprising Pseudomonas Aeruginosa bacteria are provided by detecting pyocyanin. The invention relates to electrochemical methods and devices that offer a simple and inexpensive alternative for immediate identification of bacterial infection due to the presence of Pseudomonas aeruginosa. In some embodiments, an inexpensive, disposable electrochemical sensor can be used to rapidly screen for the presence of P. aeruginosa in clinical wound effluent samples. |
| FILED | Wednesday, September 16, 2015 |
| APPL NO | 15/511735 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 38/12 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502715 (20130101) B01L 2300/02 (20130101) B01L 2300/0636 (20130101) B01L 2300/0645 (20130101) Apparatus for Enzymology or Microbiology; C12M 1/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/04 (20130101) C12Q 1/12 (20130101) Original (OR) Class C12Q 1/18 (20130101) C12Q 1/22 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/48 (20130101) G01N 27/327 (20130101) G01N 33/48707 (20130101) G01N 33/48735 (20130101) G01N 2333/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316379 | Gross et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Cameron T. Gross (Evanston, Illinois); Yao Du (Evanston, Illinois); Xu Zhang (Evanston, Illinois); Dieter Isheim (Chicago, Illinois); Semyon Vaynman (Highland Park, Illinois); Yip-Wah Chung (Wilmette, Illinois); Zilin Jiang (Evanston, Illinois); Allan V. Mathai (Evanston, Illinois) |
| ABSTRACT | Steel compositions are provided. A steel composition may include iron; from 0.015 to 0.06 wt. % carbon; from 9 to 12 wt. % chromium; from 0.75 to 1.5 wt. % manganese; from 0.08 to 0.18 wt. % molybdenum; from 0.10 to 0.30 wt. % silicon; from 0.2 to 1.0 wt. % vanadium; from 0.05 to 1.2 wt. % niobium; and optionally, an amount of an additional precipitate forming alloying element. Methods of making the steel compositions are also provided. |
| FILED | Tuesday, October 18, 2016 |
| APPL NO | 15/296549 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/28 (20130101) C21D 6/002 (20130101) Original (OR) Class Alloys C22C 38/02 (20130101) C22C 38/04 (20130101) C22C 38/22 (20130101) C22C 38/24 (20130101) C22C 38/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316873 | Weitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David A. Weitz (Bolton, Massachusetts); Darren Roy Link (Lexington, Massachusetts); Andrew S. Utada (Japan, Japan) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David A. Weitz (Bolton, Massachusetts); Darren Roy Link (Lexington, Massachusetts); Andrew S. Utada (Japan, Japan) |
| ABSTRACT | The present invention generally relates to multiple emulsions, and to methods and apparatuses for making multiple emulsions. A multiple emulsion generally describes larger droplets that contain one or more smaller droplets therein. The larger droplets may be suspended in a third fluid in some cases. These can be useful for encapsulating species such as pharmaceutical agents, cells, chemicals, or the like. In some cases, one or more of the droplets can change form, for instance, to become solidified to form a microcapsule, a liposome, a polymerosome, or a colloidosome. Multiple emulsions can be formed in one step in certain embodiments, with generally precise repeatability, and can be tailored to include one, two, three, or more inner droplets within a single outer droplet (which droplets may all be nested in some cases). |
| FILED | Wednesday, April 08, 2015 |
| APPL NO | 14/681560 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/113 (20130101) A61K 9/1273 (20130101) A61K 9/5089 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 5/045 (20130101) B01F 5/046 (20130101) B01F 13/0059 (20130101) B01F 13/0062 (20130101) B01F 2005/0022 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/008 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 516/924 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0391 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317214 | Fourie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Dehann Fourie (Cambridge, Massachusetts); John Leonard (Newton, Massachusetts) |
| ABSTRACT | Systems and methods for determining pose parameters of an inertial measurement unit (IMU) sensor include collecting measurement data generated by IMU sensors, using a processor to temporally integrate the measurement data, including any errors, generating a temporally continuous error propagation model, and temporally integrating the model to generate one or more compensation gradients for said pose parameters. |
| FILED | Tuesday, October 25, 2016 |
| APPL NO | 15/333773 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Weapon Sights; Aiming F41G 7/36 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/16 (20130101) Original (OR) Class G01C 22/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317321 | Tillberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Paul Warren Tillberg (Cambridge, Massachusetts); Fei Chen (Cambridge, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Chih-Chieh Yu (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides a method termed protein retention ExM (proExM), in which proteins, rather than labels, are anchored to the swellable gel, using a cross-linking molecule. This proExM strategy can be used to perform nanoscale imaging of immunostained cells and tissues as well as samples expressing various FPs as fluorescent signals from genetically encoded fluorescent proteins and/or conventional fluorescently labeled secondary antibodies and streptavidin that are directly anchored to the gel are preserved even when subjected to the nonspecific proteolytic digestion. |
| FILED | Friday, August 05, 2016 |
| APPL NO | 15/229545 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) Original (OR) Class G01N 1/36 (20130101) G01N 33/582 (20130101) G01N 33/6803 (20130101) G01N 2001/302 (20130101) G01N 2001/307 (20130101) G01N 2333/95 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317324 | Ownby et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of the University of Alabama, fo (Huntsville, Alabama) |
| ASSIGNEE(S) | Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in Huntsville (Huntsville, Alabama) |
| INVENTOR(S) | Kalob Ownby (Florence, Alabama); Mark Creel (Cullman, Alabama); Jordan Fulmer (Huntsville, Alabama); Matt Fulmer (Muscle Shoals, Alabama); Michael Henry (Madison, Alabama); Dung Tuan Le (Opelika, Alabama); Melissa Lee (Madison, Alabama); Derek Odom (Ardmore, Alabama); Russ Walton (Hunsville, Alabama); Jeffrey Evans (Priceville, Alabama) |
| ABSTRACT | A specimen testing system has holders that hold a specimen for testing. The holders brace the specimen so that a load may be applied. A load applicator applies a load to the specimen at a location that is between the holders bracing the specimen. A user may adjust the load applicator until it applies the desired load to the specimen. If desired, a user may apply rotation to a specimen while it is experiencing a load by using a specimen rotation system. The user may continue to adjust the load applied to the specimen or continue to rotate the specimen during loading until the specimen fails. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 15/900063 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/04 (20130101) G01N 3/08 (20130101) G01N 3/20 (20130101) Original (OR) Class G01N 3/22 (20130101) G01N 3/26 (20130101) G01N 2203/0023 (20130101) G01N 2203/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317515 | Tan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Yixuan Tan (Madison, Wisconsin); Xingze Wang (Stanford, California); Zongfu Yu (Madison, Wisconsin) |
| ABSTRACT | An optical field sensor is used to make phase measurements over an area of light reflected from an object outside a field of view of the light field sensor. These phase measurements are applied to a machine learning system trained with similar phase measurements from objects outside of a field of view to identify the object within a class of objects subject to the training. |
| FILED | Friday, September 01, 2017 |
| APPL NO | 15/694119 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4914 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317549 | Rawles et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Christopher J. Rawles (Novato, California); Clifford H. Thurber (Madison, Wisconsin) |
| ABSTRACT | Systems and methods for automatically detecting and identifying seismic wave features in seismic data are provided. In general, the systems and methods utilize a nonparametric time series classification method to detect seismic wave features that may otherwise be difficult to automatically identify in seismic data. Instead of building a model by estimating parameters from the seismic data, the data itself is used to define a trained model. The systems and methods described here provide the ability to detect and identify seismic wave features with reasonably fast and extremely accurate results without needing to compute parameters. |
| FILED | Wednesday, October 29, 2014 |
| APPL NO | 14/527315 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/288 (20130101) G01V 1/307 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317597 | Cohen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Noy Cohen (Stanford, California); Marc S. Levoy (Stanford, California); Michael J. Broxton (San Francisco, California); Logan Grosenick (Brooklyn, New York); Samuel Yang (Stanford, California); Aaron Andalman (San Francisco, California); Karl A. Disseroth (Stanford, California); Mark A. Horowitz (Menlo Park, California) |
| ABSTRACT | Various aspects of the present disclosure are directed toward optics and imaging. As may be implemented with one or more embodiments, an apparatus includes one or more phase masks that operate with an objective lens and a microlens array to alter a phase characteristic of light travelling in a path from a specimen, through the objective lens and microlens array and to a photosensor array. Using this approach, the specimen can be imaged with spatial resolution characteristics provided via the altered phase characteristic, which can facilitate construction of an image with enhanced resolution. |
| FILED | Monday, August 17, 2015 |
| APPL NO | 14/828259 |
| ART UNIT | 2485 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 3/0006 (20130101) G02B 5/3083 (20130101) Original (OR) Class G02B 21/0056 (20130101) G02B 27/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317602 | Patrick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Western Washington University (Bellingham, Washington); University of Washington Through Its Center For Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | Western Washington University (Bellingham, Washington); University of Washington Through Its Center For Commercialization (Seattle, Washington) |
| INVENTOR(S) | David Patrick (Bellingham, Washington); John Gilbertson (Bellingham, Washington); Stephen McDowall (Bellingham, Washington); Christian Erickson (Bellingham, Washington); Daniel R. Gamelin (Seattle, Washington); Liam Bradshaw (Seattle, Washington); Emily Jane McLaurin (Seattle, Washington); Kathryn E. Knowles (Seattle, Washington) |
| ABSTRACT | The present disclosure describes luminescent solar concentrators that include photoluminescent nanoparticles. The photoluminescent nanoparticles include a semiconductor nanocrystal that sensitizes the luminescence of a defect. The defect can include, for example, an atom, a cluster of atoms, or a lattice vacancy. The defect can be incorporated into the semiconductor nanocrystal, adsorbed onto, or otherwise associated with the surface of the semiconductor nanocrystal. |
| FILED | Thursday, April 12, 2018 |
| APPL NO | 15/952123 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 40/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) C09K 11/565 (20130101) C09K 11/584 (20130101) C09K 11/883 (20130101) C09K 11/7706 (20130101) C09K 11/7773 (20130101) Optical Elements, Systems, or Apparatus G02B 6/0003 (20130101) Original (OR) Class G02B 19/0019 (20130101) G02B 19/0042 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/055 (20130101) H01L 31/02322 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/95 (20130101) Y10S 977/774 (20130101) Y10S 977/896 (20130101) Y10S 977/948 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318008 | Sinha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Ayan Sinha (West Lafayette, Indiana); Chiho Choi (West Lafayette, Indiana); Joon Hee Choi (West Lafayette, Indiana); Karthik Ramani (West Lafayette, Indiana) |
| ABSTRACT | A method for hand pose identification in an automated system includes providing depth map data of a hand of a user to a first neural network trained to classify features corresponding to a joint angle of a wrist in the hand to generate a first plurality of activation features and performing a first search in a predetermined plurality of activation features stored in a database in the memory to identify a first plurality of hand pose parameters for the wrist associated with predetermined activation features in the database that are nearest neighbors to the first plurality of activation features. The method further includes generating a hand pose model corresponding to the hand of the user based on the first plurality of hand pose parameters and performing an operation in the automated system in response to input from the user based on the hand pose model. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 15/380002 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/017 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/00214 (20130101) G06K 9/00389 (20130101) G06K 9/4628 (20130101) Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) Pictorial Communication, e.g Television H04N 13/271 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10319589 | Duan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Xiangfeng Duan (Los Angeles, California); Yu Huang (Los Angeles, California) |
| ABSTRACT | A method of forming a thin film includes: (1) providing an ink composition including nanoplates of a layered material disposed in a liquid dispersion medium; (2) applying the ink composition over a substrate to form a coating; and (3) annealing the coating to form a thin film of the layered material over the substrate. |
| FILED | Thursday, September 10, 2015 |
| APPL NO | 15/510618 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/005 (20130101) B05D 1/18 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/428 (20130101) H01L 21/477 (20130101) H01L 21/02381 (20130101) H01L 21/02488 (20130101) H01L 21/02568 (20130101) H01L 21/02601 (20130101) H01L 21/02628 (20130101) Original (OR) Class H01L 29/78681 (20130101) H01L 29/78684 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10319825 | Terrones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Humberto Terrones (State College, Pennsylvania); Mauricio Terrones (State College, Pennsylvania); Ana Laura Elias (State College, Pennsylvania); Nestor Perea-Lopez (State College, Pennsylvania) |
| ABSTRACT | A TMD system in which the first layered material is made of heterobilayers or multilayers with semiconducting direct band gaps is provided. The first layered material may be made of multiple layers of different TMD with different stackings, exhibiting smaller direct and indirect band gaps smaller than monolayer systems of TMD. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/724612 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/768 (20130101) H01L 21/02485 (20130101) H01L 21/02499 (20130101) H01L 21/02507 (20130101) H01L 21/02568 (20130101) H01L 21/28556 (20130101) H01L 29/24 (20130101) H01L 29/45 (20130101) Original (OR) Class H01L 29/417 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10319994 | Alcoutlabi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Mataz Alcoutlabi (Edinburg, Texas); Victor Anafo Agubra (Edinburg, Texas) |
| ABSTRACT | Tin-containing carbon fibers may be produced by centrifugal spinning of a precursor composition that includes a base polymer and a tin-containing compound. The produced fibers are heated at a temperature sufficient to convert at least a portion of the base polymer in the collected fibers into carbon fibers comprising tin. |
| FILED | Tuesday, August 16, 2016 |
| APPL NO | 15/237892 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/05 (20170801) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/364 (20130101) Original (OR) Class H01M 4/387 (20130101) H01M 4/587 (20130101) H01M 4/625 (20130101) H01M 10/052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320013 | Nguyen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| ASSIGNEE(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| INVENTOR(S) | Trung Van Nguyen (Lawrence, Kansas); Xuhai Wang (Drexel Hill, Pennsylvania) |
| ABSTRACT | A gas diffusion layer having a first major surface and a second major surface which is positioned opposite to said first major surface and an interior between said first and second major surfaces is formed. The gas diffusion layer comprises a porous carbon substrate which is directly fluorinated in the interior and is substantially free of fluorination on at least one of the first major surfaces or the second major surfaces, and preferably both surfaces. The gas diffusion layer may be formed using protective sandwich process during direct fluorination or by physically or chemically removing the C—F atomic layer at the major surfaces, for example by physical plasma etching or chemical reactive ion etching. |
| FILED | Friday, November 17, 2017 |
| APPL NO | 15/815804 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0234 (20130101) H01M 8/0245 (20130101) H01M 8/1004 (20130101) H01M 8/04201 (20130101) Original (OR) Class H01M 2008/1095 (20130101) H01M 2300/0082 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/56 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320295 | Crossley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lion Semiconductor Inc. (San Francisco, California) |
| ASSIGNEE(S) | Lion Semiconductor Inc. (San Francisco, California) |
| INVENTOR(S) | John Crossley (Oakland, California); Hanh-Phuc Le (Superior, Colorado); Alberto Alessandro Angelo Puggelli (Oakland, California) |
| ABSTRACT | The present disclosure provides an asymmetric switching capacitor regulator that is capable of providing an output voltage, covering a wide voltage range, with a high efficiency. The disclosed switching capacitor regulator is configured to generate a wide range of an output voltage by differentiating a voltage across one or more switching capacitors from a voltage across the rest of the switching capacitors in the switching capacitor regulator. |
| FILED | Saturday, February 17, 2018 |
| APPL NO | 15/898499 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/14 (20130101) H02M 3/07 (20130101) H02M 3/158 (20130101) Original (OR) Class H02M 2001/007 (20130101) H02M 2001/4291 (20130101) H02M 2003/072 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 70/126 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320610 | Matni et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Nikolai Matni (Pasadena, California); John Comstock Doyle (Pasadena, California) |
| ABSTRACT | Data network components and frameworks for the control and optimization of network traffic using layered architectures, according to embodiments of the invention, are disclosed. In one embodiment, a data network comprises a switch, a data link, a tracking processor, and a planning processor. The planning processor is configured to generate a reference trajectory by receiving a local system state from the tracking processor, calculating a reference trajectory by solving a planning problem, and sending the reference trajectory to the tracking processor. The tracking processor is configured to track the reference trajectory by determining a set of states of the switch over a time interval, sending a local system state to the planning processor, receiving the reference trajectory from the planning processor, computing a control action by solving a tracking problem based on the reference trajectory, determining an instruction based on the control action, and sending the instruction to the switch. |
| FILED | Monday, October 17, 2016 |
| APPL NO | 15/295507 |
| ART UNIT | 2479 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/147 (20130101) H04L 41/0823 (20130101) Original (OR) Class H04L 43/0876 (20130101) H04L 45/42 (20130101) H04L 49/25 (20130101) H04L 49/552 (20130101) Wireless Communication Networks H04W 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10316795 | Bostwick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vector Launch Inc. (Tucson, Arizona) |
| ASSIGNEE(S) | Vector Launch Inc. (Tucson, Arizona) |
| INVENTOR(S) | Christopher Bostwick (Long Beach, California); John Garvey (Long Beach, California); Christopher Anderson (San Marcos, California); Eric Besnard (Long Beach, California) |
| ABSTRACT | Provided herein are various improvements to rocket engine components and rocket engine operational techniques. In one example, a rocket engine propellant injection apparatus is provided that includes a manifold formed into a single body by an additive manufacturing process and comprising a fuel cavity and an oxidizer cavity. The manifold also includes one or more propellant feed stubs, the one or more propellant feed stubs protruding from the manifold and formed into the single body of the manifold by the additive manufacturing process, with at least a first stub configured to carry fuel to the fuel cavity and at least a second stub configured to carry oxidizer to the oxidizer cavity. The manifold also includes a plurality of injection features formed by apertures in a face of the manifold, ones of the plurality of injection features configured to inject the fuel and the oxidizer for combustion. |
| FILED | Friday, August 10, 2018 |
| APPL NO | 16/101000 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/008 (20130101) B22F 3/1055 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Jet-propulsion Plants F02K 9/52 (20130101) Original (OR) Class F02K 9/566 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/31 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317292 | Liaghati et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Amir Liaghati (Huntsville, Alabama); Jordan Miller (Huntsville, Alabama); David Rushing (Madison, Alabama); John Blumer (Huntsville, Alabama) |
| ABSTRACT | A two-wire resistance temperature detector (RTD) includes an RTD sensor having a sensor resistance that changes in correspondence with changes in the temperature of the RTD sensor. The two-wire RTD additionally includes a pair of leads electrically coupling the RTD sensor to a control unit having a pulse generator for generating a first current pulse and a second current pulse. The two-wire RTD also includes a switch electrically coupled between the pair of leads and operable in an open state when subjected to the first current pulse and operable in a closed state when subjected to the second current pulse. The open state causes the first current pulse to flow through the pair of leads and the RTD sensor. The closed state causes the second current pulse to flow through the pair of leads. The switch enables the control unit to determine the sensor resistance and corresponding sensor temperature. |
| FILED | Friday, February 24, 2017 |
| APPL NO | 15/441948 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317521 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Lihua Li (Ellicott City, Maryland); Matthew McLinden (Greenbelt, Maryland); Michael Coon (Columbia, Maryland); Gerald Heymsfield (North Potomac, Maryland); Vijay Subbaraman Venkatesh (Annapolis, Maryland) |
| ABSTRACT | The disclosed subject matter relates to Frequency Diversity Pulse Pair (FDPP) methods and technology implemented by, alternating the order of the pulse pair transmitted or order of the group of multiple pulses transmitted, the pulses differentiated based on the center frequency of each transmitted pulse. For example, where a pair of transmitted pulses have center frequencies f1 and f2, the pulses transmitted in pairs such that the first pair may be f1 followed by f2 and the second pair are a different order, such as f2 followed by f1. |
| FILED | Thursday, June 16, 2016 |
| APPL NO | 15/184048 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/024 (20130101) G01S 13/581 (20130101) Original (OR) Class G01S 13/953 (20130101) G01S 13/955 (20130101) Technologies for Adaptation to Climate Change Y02A 90/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10318656 | Cox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Kelsea Cox (Harvest, Alabama); Laura S. Kang (Seattle, Washington); David E. Hall (Madison, Alabama); Vincent O. Dominguez (Harvest, Alabama); Dwaine K. Coates (Madison, Alabama) |
| ABSTRACT | Systems, computer readable media, and method concern determining operational parameters of an inventory of components to be included in a battery. The components can include storage components and electrical components. The method includes generating a system of equations that describe suitable combinations of components in locations in a battery design layout for the battery, the system of equations being generated based at least partially on rules and constraints, and includes analyzing the system of equations using integer optimization. The integer optimization can optimizes, based at least partially on the operational parameters, one or more objective functions in the system of equations to determine at least one solution for the battery design layout, and the at least one solution can include a set of the components for the locations in the battery design layout for the battery. The method includes providing, via an interface, the at least one solution. |
| FILED | Tuesday, April 26, 2016 |
| APPL NO | 15/138815 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 17/11 (20130101) G06F 17/50 (20130101) Original (OR) Class G06F 17/5009 (20130101) G06F 2217/06 (20130101) G06F 2217/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10320015 | Burke |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth A. Burke (Chardon, Ohio) |
| ABSTRACT | Systems, methods, and other embodiments associated with fuel cell power management. According to one embodiment, a fuel cell stack includes a plurality of fuel cells producing electric potentials. An electric potential of a fuel cell is measured as a fuel cell voltage. The fuel cell stack further includes a plurality of connection points including a ground, a first connection point, and a second connection point. The first connection point draws a first voltage based on combined fuel cell voltages of a first set of fuel cells of the plurality of fuel cells. The second connection point draws a second voltage based on the combined fuel cell voltages of a second set of fuel cells of the plurality of fuel cells. |
| FILED | Friday, March 06, 2015 |
| APPL NO | 14/640866 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/04559 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10314683 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tepha, Inc. (Lexington, Massachusetts) |
| ASSIGNEE(S) | Tepha, Inc. (Lexington, Massachusetts) |
| INVENTOR(S) | David P. Martin (Arlington, Massachusetts); Said Rizk (Windham, New Hampshire); Ajay Ahuja (Long Grove, Illinois); Simon F. Williams (Sherborn, Massachusetts) |
| ABSTRACT | Absorbable polyester fibers, braids, and surgical meshes with prolonged strength retention have been developed. These devices are preferably derived from biocompatible copolymers or homopolymers of 4-hydroxybutyrate. These devices provide a wider range of in vivo strength retention properties than are currently available, and could offer additional benefits such as anti-adhesion properties, reduced risks of infection or other post-operative problems resulting from absorption and eventual elimination of the device, and competitive cost. The devices may also be particularly suitable for use in pediatric populations where their absorption should not hinder growth, and provide in all patient populations wound healing with long-term mechanical stability. The devices may additionally be combined with autologous, allogenic and/or xenogenic tissues to provide implants with improved mechanical, biological and handling properties. |
| FILED | Thursday, July 21, 2016 |
| APPL NO | 15/215878 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0063 (20130101) Original (OR) Class A61F 2002/0068 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/48 (20130101) A61L 31/06 (20130101) A61L 31/06 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0004 (20130101) B29C 47/0014 (20130101) B29C 71/0072 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 67/04 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/16 (20130101) D01D 5/088 (20130101) D01D 5/098 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/62 (20130101) D01F 6/84 (20130101) D01F 6/625 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/1362 (20150115) Y10T 428/1369 (20150115) Y10T 428/249922 (20150401) Y10T 442/10 (20150401) Y10T 442/183 (20150401) Y10T 442/184 (20150401) Y10T 442/2525 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314802 | Stock et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Signum Biosciences, Inc. (Monmouth Junction, New Jersey) |
| ASSIGNEE(S) | Signum Biosciences, Inc. (Monmouth Junction, New Jersey) |
| INVENTOR(S) | Jeffry B. Stock (Princeton, New Jersey); Maxwell Stock (Boulder, Colorado); Keshava Rapole (Edison, New Jersey); Seung-Yub Lee (Princeton, New Jersey); Michael Voronkov (Pennington, New Jersey); Eduardo Perez (Somerset, New Jersey); Joel Gordon (Prinecton Junction, New Jersey); Shuyi Chen (Somerset, New Jersey); Jinglong Chen (Newark, New Jersey) |
| ABSTRACT | Among other things, the present invention provides novel isoprenyl compounds capable of effectively modulating inflammatory responses and pharmaceutical, cosmetic, cosmeceutical and topical compositions comprising these isoprenyl compounds. Anti-inflammatory compounds of the present invention are useful in treating or preventing diseases or conditions associated with inflammation. Proinflammatory compounds of the present invention are useful in treating or preventing diseases or conditions associated with suppression of inflammatory responses. Thus, the present invention also provides methods useful in the treatment or prevention of diseases or conditions associated with inflammation as well as methods useful in the treatment or prevention of diseases or conditions associated with suppression of inflammatory responses. |
| FILED | Tuesday, August 01, 2017 |
| APPL NO | 15/665922 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/197 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 243/34 (20130101) C07C 321/18 (20130101) C07C 323/59 (20130101) C07C 335/08 (20130101) C07C 2601/02 (20170501) C07C 2601/14 (20170501) Heterocyclic Compounds C07D 207/16 (20130101) C07D 209/18 (20130101) C07D 209/48 (20130101) C07D 217/26 (20130101) C07D 243/34 (20130101) C07D 295/145 (20130101) C07D 307/54 (20130101) C07D 333/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10314839 | Jenkins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elysium Therapeutics, Inc. (Danville, California) |
| ASSIGNEE(S) | Elysium Therapeutics, Inc. (Danville, California) |
| INVENTOR(S) | Thomas E. Jenkins (Half Moon Bay, California) |
| ABSTRACT | The present invention provides a composition comprising an opioid agonist, and a polymer-antagonist conjugate. The polymer-antagonist conjugate preferably does not hydrolyze upon administration to a patient, and does not bind to the opioid receptors. The covalent bond between the polymer and the antagonist in the conjugate is broken over a defined period of time to release the antagonist into the formulation. The released antagonist attenuates the liking of the agonist, thereby eliminating the incentive to the diversion of the medicines. |
| FILED | Tuesday, October 20, 2015 |
| APPL NO | 14/918464 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/4866 (20130101) A61K 31/485 (20130101) Original (OR) Class A61K 31/485 (20130101) A61K 45/06 (20130101) A61K 47/55 (20170801) A61K 47/60 (20170801) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317313 | Becker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ASCENDANT ENGINEERING SOLUTIONS (Austin, Texas) |
| ASSIGNEE(S) | Ascendant Engineering Solutions (Austin, Texas) |
| INVENTOR(S) | Keith Eric Becker (Georgetown, Texas); George Gregory Mooty (Austin, Texas) |
| ABSTRACT | Embodiments of the present invention are directed to an apparatus, system and associated method of operation that allows medium weight Class II equipment to be shock tested using a Medium Weight Shock Machine (MWSM) in a manner that adequately simulates the required shock response exhibited when subjected to underwater explosion (UNDEX), Heavyweight testing utilizing a FSP. Advantageously, such an apparatus, system and associated method allows for testing of Class II medium weight (e.g., about 500-4500 lbs.) equipment (e.g., submarine and surface vessel equipment) utilizing an MWSM instead of Heavyweight testing utilizing a Floating Shock Platform (FSP). Testing of Class II medium weight equipment in this manner significantly reduces cost of testing such equipment and increases safety associated with testing such equipment. |
| FILED | Tuesday, November 08, 2016 |
| APPL NO | 15/346108 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 7/08 (20130101) Original (OR) Class G01M 10/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317532 | Jannson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Physical Optics Corporation (Torrance, California) |
| ASSIGNEE(S) | PHYSICAL OPTICS CORPORATION (Torrance, California) |
| INVENTOR(S) | Tomasz Jannson (Torrance, California); Ranjit Pradhan (Torrance, California); Andrew Kostrzewski (Torrance, California) |
| ABSTRACT | A laser is used to emit a diverging laser flash configured to illuminate a detection zone. A pseudoimaging optical receiver system is used to detect reflections from objects in the detection zone. The receiver system includes a time-gated photodetector array that is used to record signatures in a voxel array. A voxel processing module receives the voxel array and detects a reference clutter signal within the array. Potential targets are then detected according to target signals in relation to the reference clutter signal. |
| FILED | Monday, June 26, 2017 |
| APPL NO | 15/633380 |
| ART UNIT | 2484 — Recording and Compression |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/66 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10314816 | Weibel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Douglas Benjamin Weibel (Madison, Wisconsin); Ye Jin Eun (Cambridge, Massachusetts); Marie Hazel Foss (Hillsboro, Oregon); Katherine Ann Hurley (Madison, Wisconsin) |
| ABSTRACT | Described herein are antimicrobial compounds identified via a high-throughput inhibitor screen of the in vitro activity of MipZ, which is an ATPase that regulates division site placement in Caulobacter crescentus. The compounds and their analogs are active against bacterial membranes and thus represent a novel class of antimicrobial compounds. The antimicrobial compounds are effective against both actively growing bacterial cells as well as bacterial cells in the stationary phase. The antimicrobial compounds are also effective against bacteria in biofilms. |
| FILED | Monday, June 10, 2013 |
| APPL NO | 13/913912 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/403 (20130101) Original (OR) Class A61K 31/4045 (20130101) Heterocyclic Compounds C07D 209/04 (20130101) C07D 209/44 (20130101) C07D 209/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316295 | Schmitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Anthony Paul Schmitt (State College, Pennsylvania); Phuong Tieu Schmitt (State College, Pennsylvania); Greeshma Vivekananda Ray (State College, Pennsylvania) |
| ABSTRACT | Provided are modified virus-like particles (VLPs) of paramyxoviruses, compositions containing them, methods of using the VLPs for delivery of any particular protein of interest to any of a variety of cells, kits that contain expression vectors for making, using and detecting VLPs, and methods for screening for anti-viral compounds using the VLPs. The modified VLPs contain a contiguous recombinant polypeptide that contains i) all or a segment of a C-terminal domain of a paramyxovirus nucleocapsid protein and ii) a polypeptide sequence of a distinct protein. Non-covalent complexes of paramyxovirus M protein and fusion proteins that contain a C-terminal domain of a paramyxovirus nucleocapsid protein and a polypeptide sequence of a distinct protein are provided, as are non-covalent complexes of cells, and cell receptors, with modified VLPs. |
| FILED | Monday, December 19, 2016 |
| APPL NO | 15/383324 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 14/8121 (20130101) C07K 16/1027 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/0069 (20130101) C12N 9/0089 (20130101) C12N 2760/18022 (20130101) C12N 2760/18023 (20130101) C12N 2760/18034 (20130101) C12N 2760/18222 (20130101) C12N 2760/18223 (20130101) C12N 2760/18234 (20130101) C12N 2760/18252 (20130101) C12N 2760/18722 (20130101) C12N 2760/18723 (20130101) C12N 2760/18734 (20130101) Enzymes C12Y 113/12005 (20130101) C12Y 115/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10314683 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tepha, Inc. (Lexington, Massachusetts) |
| ASSIGNEE(S) | Tepha, Inc. (Lexington, Massachusetts) |
| INVENTOR(S) | David P. Martin (Arlington, Massachusetts); Said Rizk (Windham, New Hampshire); Ajay Ahuja (Long Grove, Illinois); Simon F. Williams (Sherborn, Massachusetts) |
| ABSTRACT | Absorbable polyester fibers, braids, and surgical meshes with prolonged strength retention have been developed. These devices are preferably derived from biocompatible copolymers or homopolymers of 4-hydroxybutyrate. These devices provide a wider range of in vivo strength retention properties than are currently available, and could offer additional benefits such as anti-adhesion properties, reduced risks of infection or other post-operative problems resulting from absorption and eventual elimination of the device, and competitive cost. The devices may also be particularly suitable for use in pediatric populations where their absorption should not hinder growth, and provide in all patient populations wound healing with long-term mechanical stability. The devices may additionally be combined with autologous, allogenic and/or xenogenic tissues to provide implants with improved mechanical, biological and handling properties. |
| FILED | Thursday, July 21, 2016 |
| APPL NO | 15/215878 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0063 (20130101) Original (OR) Class A61F 2002/0068 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/48 (20130101) A61L 31/06 (20130101) A61L 31/06 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0004 (20130101) B29C 47/0014 (20130101) B29C 71/0072 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 67/04 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/16 (20130101) D01D 5/088 (20130101) D01D 5/098 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/62 (20130101) D01F 6/84 (20130101) D01F 6/625 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/1362 (20150115) Y10T 428/1369 (20150115) Y10T 428/249922 (20150401) Y10T 442/10 (20150401) Y10T 442/183 (20150401) Y10T 442/184 (20150401) Y10T 442/2525 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10316428 | Schujman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Crystal IS, Inc. (Green Island, New York) |
| ASSIGNEE(S) | Crystal IS, Inc. (Green Island, New York) |
| INVENTOR(S) | Sandra B. Schujman (Niskayuna, New York); Shailaja P. Rao (Albany, New York); Robert T. Bondokov (Watervliet, New York); Kenneth E. Morgan (Castleton, New York); Glen A. Slack (Scotia, New York); Leo J. Schowalter (Latham, New York) |
| ABSTRACT | In various embodiments, methods of forming single-crystal AlN include providing a substantially undoped polycrystalline AlN ceramic having an oxygen concentration less than approximately 100 ppm, forming a single-crystal bulk AlN crystal by a sublimation-recondensation process at a temperature greater than approximately 2000° C., and cooling the bulk AlN crystal to a first temperature between approximately 1500° C. and approximately 1800° C. at a first rate less than approximately 250° C./hour. |
| FILED | Monday, August 15, 2016 |
| APPL NO | 15/237113 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/00 (20130101) C30B 23/002 (20130101) C30B 23/02 (20130101) C30B 23/066 (20130101) Original (OR) Class C30B 29/403 (20130101) C30B 33/02 (20130101) C30B 35/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02389 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10316313 | Corgie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithica, New York) |
| INVENTOR(S) | Stephane C. Corgie (Ithaca, New York); Patarawan Kahawong (Nakhonsithammarat, Thailand); Emmanuel P. Giannelis (Ithaca, New York); Larry P. Walker (Ithaca, New York) |
| ABSTRACT | A composition comprising mesoporous aggregates of magnetic nanoparticles and free-radical producing enzyme (i.e., enzyme-bound mesoporous aggregates), wherein the mesoporous aggregates of magnetic nanoparticles have mesopores in which the free-radical-producing enzyme is embedded. Methods for synthesizing the enzyme-bound mesoporous aggregates are also described. Processes that use said enzyme-bound mesoporous aggregates for depolymerizing lignin, removing aromatic contaminants from water, and polymerizing monomers polymerizable by a free-radical reaction are also described. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 15/380104 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/003 (20130101) B01J 35/0033 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 3/342 (20130101) C02F 2305/08 (20130101) Derivatives of Natural Macromolecular Compounds C08H 6/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/0065 (20130101) C12N 11/14 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/181 (20130101) C12P 2201/00 (20130101) Enzymes C12Y 111/01007 (20130101) C12Y 111/01013 (20130101) C12Y 111/01014 (20130101) C12Y 111/01016 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317358 | Sagues et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alberto A. Sagues (Lutz, Florida); William Clarence Ruth (St. Petersburg, Florida); Leonidas Philip Emmenegger (Tarpon Springs, Florida); Enrique Alberto Paz Velasquez (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Alberto A. Sagues (Lutz, Florida); William Clarence Ruth (St. Petersburg, Florida); Leonidas Philip Emmenegger (Tarpon Springs, Florida); Enrique Alberto Paz Velasquez (Tampa, Florida) |
| ABSTRACT | In one embodiment, reinforced soil is assessed using a non-contact method including positioning a reference electrode in close proximity to a surface of the soil without contacting the electrode to the soil surface, vibrating the electrode with a vibration generator, and measuring an electrical potential difference between the electrode and the soil surface, the potential difference being indicative of the condition of a portion of a reinforcement member positioned below the soil surface at the location of the electrode. |
| FILED | Wednesday, March 15, 2017 |
| APPL NO | 15/460156 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 17/04 (20130101) G01N 17/006 (20130101) G01N 27/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10315797 | Lee |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Jim E. Lee (St. Leonard, Maryland) |
| ABSTRACT | Embodiments of a reusable stackable shipping box are provided herein. The reusable stackable shipping box may be reused and cleaned without causing harm to the integrity of the box. In addition, the box is slightly tapered in shape such that the box may be stacked upon and within other boxes for ease in shipping and organization. |
| FILED | Thursday, May 31, 2018 |
| APPL NO | 15/994886 |
| ART UNIT | 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 5/001 (20130101) Original (OR) Class B65D 5/10 (20130101) B65D 5/14 (20130101) B65D 5/0245 (20130101) B65D 5/0281 (20130101) B65D 5/4266 (20130101) B65D 5/4608 (20130101) B65D 5/48024 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/807 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10317229 | Bonnell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Sates Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Clayton C. Bonnell (Fairfax, Virginia); Gary C. Reblin (Falls Church, Virginia) |
| ABSTRACT | A method and system for generating a location identifier using a location code and a grid coordinate. The location code corresponds to a defined geographical area, such as a postal code or an area code. A grid coordinate can be determined based on destination location information, such as an address, a GPS-determined position, or other reference to a specific physical location. The location identifier is combined with the location code to generate a location identifier, which can be encoded in a computer readable format and placed on items for use in a distribution network. The location identifier can be used to facilitate domestic or international distribution of items using a common format or addressing scheme. The domestic and foreign distribution networks read and interpret location identifiers in order to deliver items. |
| FILED | Friday, December 01, 2017 |
| APPL NO | 15/829154 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/26 (20130101) G01C 21/362 (20130101) G01C 21/3476 (20130101) Original (OR) Class G01C 21/3623 (20130101) G01C 21/3629 (20130101) G01C 21/3661 (20130101) Electric Digital Data Processing G06F 16/29 (20190101) G06F 16/9537 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/083 (20130101) Wireless Communication Networks H04W 4/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10316075 | Vandenbark et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Arthur A. Vandenbark (Portland, Oregon); Roberto Meza-Romero (Hillsboro, Oregon); Gil Benedek (Portland, Oregon); Gregory G. Burrows (Portland, Oregon) |
| ABSTRACT | Recombinant polypeptides comprising a DRα1 domain, an antigenic peptide, and a linker sequence are disclosed. The linker sequence comprises a first glycine-serine spacer, a thrombin cleavage site and a second glycine-serine spacer. Further disclosed are pharmaceutical compositions comprising the recombinant polypeptides, methods of treating inflammatory disease using said pharmaceutical compositions, and expression constructs comprising nucleic acids that encode the recombinant polypeptides. |
| FILED | Friday, October 03, 2014 |
| APPL NO | 14/506502 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) A61K 2039/605 (20130101) A61K 2039/627 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 14/70539 (20130101) C07K 2319/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 10316506 | Hawley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Environmental Protection Agency (Washington, District of Columbia); Sustainable Streams, LLC (Louisville, Kentucky) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF U.S. ENVIRONMENTAL PROTECTION AGENCY (Washington, District of Columbia); SUSTAINABLE STREAMS, LLC (Washington, District of Columbia) |
| INVENTOR(S) | Robert J. Hawley (Louisville, Kentucky); James A. Goodrich (Cincinnati, Ohio); Katherine R. MacMannis (Carmel, Indiana) |
| ABSTRACT | Aspects of a detention pond retrofit device for detention basin outlet control provide structures designed to throttle stormwater flow and maintain the rate at which water is discharged from the system below Qcritical, the flow rate at which erosion and down cutting of the receiving stream would begin, based on channel morphology and bed material resistance. The primary goal of the device is to induce increased flow detention during low to moderate rain events, while providing similar hydraulic performance during large events to that of the detention basin performance prior to the installation of the retrofit unit. This is achieved through a “T” or “Y” design with split flow paths, in which the lower path is hydraulically restricted through the installation of structures while the upper path is unrestricted. |
| FILED | Friday, July 18, 2014 |
| APPL NO | 14/335567 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Sewers; Cesspools E03F 5/106 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) Y10T 137/794 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10318259 | Zhang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Yongzhi Zhang (Wayland, Massachusetts) |
| ABSTRACT | An apparatus for automatically converting a control flow program into a data flow program comprises a non-transitory machine-readable medium and a translator stored in the machine-readable medium. The translator, when executed by a data processing system, enables the data processing system to (a) automatically generate a control dependency graph for a control flow program, (b) automatically generate a data flow graph based at least in part on the control dependency graph, and (c) automatically generate a data flow program based at least in part on the data flow graph. In one embodiment or scenario, the translator may also automatically insert a switch instruction into the data flow program, in response to a determination that a variable of the control flow program is defined in one control dependency region and used in a different control dependency region. Other embodiments are described and claimed. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 15/609583 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/20 (20130101) G06F 8/34 (20130101) G06F 8/433 (20130101) Original (OR) Class G06F 15/825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 10317321 | Tillberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Paul Warren Tillberg (Cambridge, Massachusetts); Fei Chen (Cambridge, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Chih-Chieh Yu (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides a method termed protein retention ExM (proExM), in which proteins, rather than labels, are anchored to the swellable gel, using a cross-linking molecule. This proExM strategy can be used to perform nanoscale imaging of immunostained cells and tissues as well as samples expressing various FPs as fluorescent signals from genetically encoded fluorescent proteins and/or conventional fluorescently labeled secondary antibodies and streptavidin that are directly anchored to the gel are preserved even when subjected to the nonspecific proteolytic digestion. |
| FILED | Friday, August 05, 2016 |
| APPL NO | 15/229545 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) Original (OR) Class G01N 1/36 (20130101) G01N 33/582 (20130101) G01N 33/6803 (20130101) G01N 2001/302 (20130101) G01N 2001/307 (20130101) G01N 2333/95 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 10317196 | Laine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts); Luna Innovations Incorporated (Roanoke, Virginia) |
| ASSIGNEE(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Juha-Pekka J. Laine (Boston, Massachusetts); Bruce Dow (West Newbury, Massachusetts); Marc McConley (Andover, Massachusetts); Gregory Blasche (Burlington, Massachusetts); Paul Bohn (St. Petersburg, Florida); Matthew S. Bottkol (Boston, Massachusetts); Michael Ricard (Natick, Massachusetts); Evan M. Lally (Blacksburg, Virginia); Sandra M. Klute (Blacksburg, Virginia); Matthew T. Reaves (Baltimore, Maryland); Emily H. Templeton (Blacksburg, Virginia); James Donna (Watertown, Massachusetts) |
| ABSTRACT | Systems and methods for determining the shape and/or position of an object are described. A fiber optic shape sensor (FOSS) may be used in combination with one or more inertial measurement units (IMUs) to mutually cross-correct for errors in the sensors' measurements of position and/or orientation. The IMU(s) may be attached to the FOSS's optical fiber, such that each IMU measures the orientation of a corresponding portion of the optical fiber. The position and shape of the optical fiber can then be determined based on the measurements obtained from the IMU(s) and the measurements obtained from the FOSS. For example, the FOSS measurements and the IMU measurements can be provided to a state estimation unit (e.g., a Kalman filter), which can estimate the position and/or shape of the optical fiber based on those measurements. In some embodiments, the estimates of position are used for navigation of tethered mobile devices. |
| FILED | Friday, June 17, 2016 |
| APPL NO | 15/186051 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/16 (20130101) Original (OR) Class Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/268 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. Agency for International Development (USAID)
| US 10314990 | Richards-Kortum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Rebecca Richards-Kortum (Houston, Texas); Z. Maria Oden (Houston, Texas); Jocelyn Kaye Brown (Pittsburgh, Pennsylvania); Robert H. J. Miros (San Rafael, California); Elizabeth Molyneux (Blantyre, Malawi) |
| ABSTRACT | A bubble continuous positive airway pressure system may include an adjustable flow generator configured to control a flow rate of air to be delivered to a patient. A pressure-regulated delivery system is configured to control a pressure delivered to the patient interface. The delivery system is operatively connected to a pressure control tube. One end of the pressure control tube is submerged in a liquid. A patient interface is configured to transfer pressure from the pressure control tube to the patient's airway. |
| FILED | Wednesday, May 27, 2015 |
| APPL NO | 14/722393 |
| ART UNIT | 3764 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Hats; Head Coverings A42B 1/02 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0003 (20140204) A61M 16/12 (20130101) A61M 16/20 (20130101) A61M 16/0066 (20130101) Original (OR) Class A61M 16/0672 (20140204) A61M 16/0683 (20130101) A61M 16/0816 (20130101) A61M 2016/003 (20130101) A61M 2202/0208 (20130101) A61M 2205/3334 (20130101) A61M 2205/3348 (20130101) A61M 2240/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10316058 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhifeng Ren (Houston, Texas); Dong Cai (Houston, Texas); Zhen Yang (Houston, Texas); University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Zhifeng Ren (Houston, Texas); Dong Cai (Houston, Texas); Zhen Yang (Houston, Texas) |
| ABSTRACT | A method of extracting biomolecules from live cells comprising: introducing a plurality of magnetized carbon nanotubes (MCNTs) into a live cell, wherein the MCNTs penetrate the cell membrane under a magnetic force; spearing the MCNTs through the cell under the magnetic force, wherein a biomolecule attaches to at least a portion of the MCNTs to form a biomolecule loaded MCNT; removing at least a portion of the biomolecule loaded MCNTs from the cell under the magnetic force; and collecting at least a portion of the biomolecule loaded MCNTs. |
| FILED | Tuesday, August 04, 2015 |
| APPL NO | 15/501796 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 1/14 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54326 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10319556 | Jing et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Euclid TechLabs, LLC (Solon, Ohio) |
| ASSIGNEE(S) | Euclid Techlabs, LLC (Solon, Ohio) |
| INVENTOR(S) | Chunguang Jing (Naperville, Illinois); Jiaqi Qiu (Willowbrook, Illinois); Sergey V Baryshev (Lemont, Illinois); June W Lau (Rockville, Maryland); Yimei Zhu (East Setauket, New York) |
| ABSTRACT | An ElectroMagnetic-Mechanical Pulser (“EMMP”) generates electron pulses at a continuously tunable rate between 100 MHz and 20-50 GHz, with energies up to 0.5 MeV, duty cycles up to 20%, and pulse widths between 100 fs and 10 ps. A dielectric-filled Traveling Wave Transmission Stripline (“TWTS”) that is terminated by an impedance-matching load such as a 50 ohm load imposes a transverse modulation on a continuous electron beam. The dielectric is configured such that the phase velocity of RF propagated through the TWTS matches a desired electron energy, which can be between 100 and 500 keV, thereby transferring electromagnetic energy to the electrons. The beam is then chopped into pulses by an adjustable aperture. Pulse dispersion arising from the modulation is minimized by a suppressing section that includes a mirror demodulating TWTS, so that the spatial and temporal coherence of the pulses is substantially identical to the input beam. |
| FILED | Friday, December 02, 2016 |
| APPL NO | 15/368051 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/045 (20130101) Original (OR) Class H01J 37/3178 (20130101) H01J 2237/065 (20130101) H01J 2237/0432 (20130101) H01J 2237/2802 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
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THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 11, 2019.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
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Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
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THE PANEL
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FUNDED BY
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Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
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Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190611.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page