FedInvent™ Patents
Patent Details for Tuesday, July 02, 2019
This page was updated on Monday, March 27, 2023 at 05:50 AM GMT
Department of Health and Human Services (HHS)
| US 10334829 | Ebert et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Benjamin Levine Ebert (Boston, Massachusetts); Jan Krönke (Boston, Massachusetts); Steven A. Carr (Cambridge, Massachusetts); Namrata D. Udeshi (Cambridge, Massachusetts); Emma Fink (Boston, Massachusetts) |
| ABSTRACT | The present invention features a knock-in mouse comprising a mutation in an endogenous CRBN locus and methods of use thereof. |
| FILED | Tuesday, April 17, 2018 |
| APPL NO | 15/955073 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) Original (OR) Class A01K 2217/072 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/94 (20130101) G01N 33/5011 (20130101) G01N 33/5088 (20130101) G01N 33/57496 (20130101) G01N 2333/47 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335037 | Jolly et al. |
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| FUNDED BY |
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| APPLICANT(S) | Siemens Healthcare GmbH (Erlangen, Germany) |
| ASSIGNEE(S) | Siemens Healthcare GmbH (Erlangen, Germany) |
| INVENTOR(S) | Marie-Pierre Jolly (Hillsborough, New Jersey); Xiaoguang Lu (West Windsor, New Jersey) |
| ABSTRACT | A method for computing global longitudinal strain from cine magnetic resonance (MR) images includes automatically detecting landmark points in each MR long axis image frame included in a cine MR image sequence. A deformation field is determined between every pair of frames based on the landmark points. Myocardial pixels in the frames are labeled using a deep learning framework to yield myocardium masks. These myocardium masks are propagated to each frame using the deformation fields. A polar transformation is performed on each of the masked frames. The contours of the myocardium in each transformed frame are computed using a shortest path algorithm. Next, longitudinal strain is calculated at every pixel in the myocardium for the polar frames using the contours of the myocardium. Then, global longitudinal strain is computed by averaging the longitudinal strain at every pixel in the myocardium of the transformed frames. |
| FILED | Tuesday, October 24, 2017 |
| APPL NO | 15/791680 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0044 (20130101) Original (OR) Class A61B 5/055 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 2209/051 (20130101) Image Data Processing or Generation, in General G06T 7/13 (20170101) G06T 2207/10088 (20130101) G06T 2207/20164 (20130101) G06T 2207/30048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335048 | Rooney et al. |
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| FUNDED BY |
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| APPLICANT(S) | William Rooney (Lake Oswego, Oregon); Charles Springer, Jr. (Portland, Oregon); Xin Li (Beaverton, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | William Rooney (Lake Oswego, Oregon); Charles Springer, Jr. (Portland, Oregon); Xin Li (Beaverton, Oregon) |
| ABSTRACT | Provided herein are methods and apparatuses for determining a level of cellular metabolic activity for a region of interest in order to detect and map on-going gliovascular unit metabolic activity using high-resolution 1H2O MRI. In one example approach, a computer-implemented method includes receiving a first set of DCE-MRI time-course data for a region, wherein a contrast agent is administered prior to imaging, identifying a region of interest from the first set of DCE-MRI time-course data for further analysis, performing shutter-speed pharmacokinetic analysis of the time-course data associated with the region of interest using computer-implemented software to obtain a finite and non-zero mean water molecule capillary lifetime in the region of interest, and indicating a level of cellular metabolic activity in the brain based on the mean water molecule capillary lifetime. |
| FILED | Monday, November 17, 2014 |
| APPL NO | 14/543071 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0013 (20130101) A61B 5/0037 (20130101) A61B 5/055 (20130101) A61B 5/0263 (20130101) Original (OR) Class A61B 5/0295 (20130101) A61B 5/742 (20130101) A61B 5/748 (20130101) A61B 5/4064 (20130101) A61B 5/4082 (20130101) A61B 5/4088 (20130101) A61B 5/4866 (20130101) A61B 5/7282 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4828 (20130101) G01R 33/5601 (20130101) G01R 33/5608 (20130101) G01R 33/56366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335049 | Griswold et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Mark Griswold (Shaker Heights, Ohio); Yun Jiang (Cleveland Heights, Ohio); Dan Ma (Cleveland, Ohio) |
| ABSTRACT | Example embodiments associated with NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. Sampling is performed in response to a fast imaging with steady state free precession (MRF-FISP) pulse sequence having an unbalanced gradient that dephases transverse magnetization. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals, and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals. The unbalanced gradient in the MRF-FISP pulse sequence reduces sensitivity to B0 in homogeneity. |
| FILED | Thursday, April 09, 2015 |
| APPL NO | 14/682183 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00 (20130101) A61B 5/055 (20130101) A61B 5/0263 (20130101) Original (OR) Class A61B 5/742 (20130101) A61B 5/4064 (20130101) A61B 17/00 (20130101) A61B 2217/00 (20130101) A61B 2218/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 1/00 (20130101) G01R 33/50 (20130101) G01R 33/448 (20130101) G01R 33/4818 (20130101) G01R 33/4828 (20130101) G01R 33/5602 (20130101) G01R 33/5608 (20130101) G01R 33/5611 (20130101) G01R 33/56366 (20130101) G01R 33/56563 (20130101) Image Data Processing or Generation, in General G06T 1/00 (20130101) G06T 2200/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335368 | Fabiilli et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Mario L. Fabiilli (Plymouth, Michigan); Christopher Wilson (Ann Arbor, Michigan); Frederic Padilla (Ann Arbor, Michigan); Francisco Martin-Saavedra (Ann Arbor, Michigan) |
| ABSTRACT | The present invention is directed to compositions and methods for delivering a tissue scaffold comprising ultrasound-triggerable agents to an individual. |
| FILED | Friday, February 26, 2016 |
| APPL NO | 15/055263 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) A61K 9/0014 (20130101) A61K 9/0024 (20130101) A61K 9/107 (20130101) A61K 9/113 (20130101) A61K 9/1075 (20130101) Original (OR) Class A61K 35/00 (20130101) A61K 38/363 (20130101) A61K 38/1825 (20130101) A61K 41/0028 (20130101) A61K 47/06 (20130101) A61K 47/10 (20130101) A61K 47/24 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/225 (20130101) A61L 27/227 (20130101) A61L 27/3804 (20130101) A61L 2300/62 (20130101) A61L 2300/252 (20130101) A61L 2300/414 (20130101) A61L 2300/418 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335382 | Hellmich et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mark Hellmich (Galveston, Texas); Jia Zhou (League City, Texas); Csaba Szabo (Seattle, Washington) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Mark Hellmich (Galveston, Texas); Jia Zhou (League City, Texas); Csaba Szabo (Seattle, Washington) |
| ABSTRACT | In certain aspects the methods comprise administering an inhibitor of hydrogen sulfide biosynthesis, a cystathionine-β-synthase (CBS) inhibitor, or a hydrogen sulfide neutralizing agent to a patient having a cancer associated with elevated production of hydrogen sulfide. |
| FILED | Monday, December 14, 2015 |
| APPL NO | 14/967649 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/22 (20130101) A61K 31/27 (20130101) A61K 31/195 (20130101) Original (OR) Class A61K 31/221 (20130101) A61K 31/222 (20130101) A61K 31/325 (20130101) A61K 31/7105 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 291/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) Enzymes C12Y 402/01022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335406 | Jenkins |
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| FUNDED BY |
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| APPLICANT(S) | Elysium Therapeutics, Inc. (Danville, California) |
| ASSIGNEE(S) | Elysium Therapeutics, Inc. (Danville, California) |
| INVENTOR(S) | Thomas E. Jenkins (Half Moon Bay, California) |
| ABSTRACT | The invention provides pharmaceutical compositions comprising macromolecular gastrointestinal enzyme-labile opioid prodrugs, co-formulated with small-molecule and/or macromolecular gastrointestinal enzyme inhibitors. The macromolecular constructs are minimally absorbed from the GI tract, and can produce non-linear pharmacokinetic profiles of the delivered opioid agonist following oral ingestion. An optional macromolecular opioid antagonist may also be present in compositions of the invention to discourage tampering by potential abusers. |
| FILED | Thursday, October 26, 2017 |
| APPL NO | 15/795126 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/55 (20170801) A61K 47/61 (20170801) A61K 47/64 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335420 | Reisfeld et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Ralph A. Reisfeld (La Jolla, California); Rong Xiang (San Diego, California); Yunping Luo (San Diego, California); Debbie Liao (San Diego, California); Ze Liu (Beijing, China PRC); Tingmei Chen (Chongqing, China PRC); Si Chen (Little Rock, Arkansas); Dan Lu (San Diego, California) |
| ABSTRACT | An aqueous tumor-targeting liposome nanoparticle composition comprises an aqueous dispersion of liposome nanoparticles. The nanoparticles preferably encapsulate an anti-cancer chemotherapeutic agent, which can be added to a pre-formed liposome composition or can be incorporated in the liposomes during the formation of the liposomes. The liposome nanoparticles comprise a legumain-targeting lipid admixed with one or more other micelle or vesicle-forming lipid materials in the form of nanoparticulate liposomes dispersed in an aqueous carrier. A preferred tumor-targeting liposome nanoparticle composition comprises a legumain-targeting lipid component and polyethylene glycol-conjugated lipid component. The legumain-targeting lipid component comprising a hydrophobic lipid portion covalently attached to a legumain-binding moiety. |
| FILED | Monday, April 24, 2017 |
| APPL NO | 15/495474 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 9/1271 (20130101) A61K 9/1272 (20130101) A61K 31/58 (20130101) Original (OR) Class A61K 31/704 (20130101) A61K 31/4164 (20130101) A61K 47/28 (20130101) A61K 47/6911 (20170801) A61K 47/6913 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335423 | Heneine et al. |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Walid Heneine (Atlanta, Georgia); Thomas M. Folks (Helotes, Texas); Robert Janssen (Atlanta, Georgia); Ronald A. Otten (Villa Rica, Georgia); Jose Gerardo Garcia Lerma (Decatur, Georgia) |
| ABSTRACT | A process is provided for protecting a primate host from a self-replicating infection by an immunodeficiency retrovirus. Protection is achieved by administering to the primate host a combination of a pharmaceutically effective amount of a nucleoside reverse transcriptase inhibitor and a pharmaceutically effective amount of a nucleotide reverse transcriptase inhibitor prior to exposure to the immunodeficiency retrovirus. The administration is effective if provided in a single dose within 24 hours of the exposure. A regime of regular daily doses is also effective in providing protection against an immunodeficiency retrovirus becoming self-replicating after infecting a primate host. A process for controlling retrovirus transmission within a population includes the administration to a subpopulation at high risk for contracting an immunodeficiency retroviral infection the detailed combination prior to sexual exposure to a source of immunodeficiency retrovirus so as to preclude the immunodeficiency retrovirus from becoming self-replicating in a member of the subpopulation. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 15/913750 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0034 (20130101) A61K 9/0053 (20130101) A61K 31/513 (20130101) A61K 31/675 (20130101) Original (OR) Class A61K 31/675 (20130101) A61K 31/683 (20130101) A61K 31/7072 (20130101) A61K 31/7072 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335425 | Bonomo et al. |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Robert Bonomo (Cleveland, Ohio); Fabio Prati (Modena MO, Italy); Emilia Caselli (Modena MO, Italy); Chiara Romagnoli (Modena MO, Italy) |
| ABSTRACT | A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one β-lactam antibiotic and at least one triazolylmethyl boronic acid. |
| FILED | Tuesday, April 24, 2018 |
| APPL NO | 15/961738 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/43 (20130101) A61K 31/69 (20130101) Original (OR) Class A61K 31/69 (20130101) A61K 31/407 (20130101) A61K 31/546 (20130101) A61K 31/546 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335426 | Huizing et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Marjan Huizing (Santa Cruz, California); William A. Gahl (Kensington, Maryland); Irini Manoli (Rockville, Maryland); Enriko Klootwijk (London, United Kingdom) |
| ABSTRACT | The invention relates to compositions and methods for treating kidney and muscle dysfunction that involves use of therapeutic amounts of N-acetyl mannosamine. |
| FILED | Tuesday, September 12, 2017 |
| APPL NO | 15/702529 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7008 (20130101) Original (OR) Class A61K 31/7012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335434 | Sanberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Paul R. Sanberg (Spring Hill, Florida); Alison E. Willing (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Paul R. Sanberg (Spring Hill, Florida); Alison E. Willing (Tampa, Florida) |
| ABSTRACT | The present invention is directed to compositions and methods for treatment of ischemic diseases and conditions, particularly myocardial, CNS/brain and limb ischemia. More particularly, the present invention provides methods of treating disorders by administering monocytes obtained from blood, including umbilical cord blood, peripheral blood, or bone marrow to an individual in need of treatment, wherein the drug is administered to the individual at a time point specifically determined to provide therapeutic efficacy. In one embodiment, the cells are for injection into ischemic myocardium for the treatment of angina. |
| FILED | Monday, July 21, 2014 |
| APPL NO | 14/336621 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) Original (OR) Class A61K 35/44 (20130101) A61K 35/51 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) C12N 5/0645 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335437 | Gillette et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Brian Gillette (Bronx, New York); Samuel Sia (New York, New York) |
| ABSTRACT | Provided are methods, pharmaceutical compositions, and kits for treatment of a metabolic condition, including obesity and type 2 diabetes by administration of a therapeutically effective amount of a cell or tissue preparation such as brown adipose microtissues to a subject, where the microtissues comprise adipose stem cells and endothelial cells. Modified approaches to creating brown adipose tissue involve differentiation of explanted white adipose tissue rather than isolation and expansion of adipose stems cells or endothelial cells and formation and differentiation of 3D cell aggregates. |
| FILED | Monday, August 12, 2013 |
| APPL NO | 14/420904 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/35 (20130101) Original (OR) Class A61K 35/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0653 (20130101) C12N 2502/28 (20130101) C12N 2506/1384 (20130101) C12N 2513/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335448 | O'Reilly et al. |
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| FUNDED BY |
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| APPLICANT(S) | The UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Philip J. O'Reilly (Hoover, Alabama); Edwin J. Blalock (Vestavia Hills, Alabama) |
| ABSTRACT | Provided herein are compositions and methods for treating or preventing fibrosis. |
| FILED | Tuesday, November 10, 2015 |
| APPL NO | 15/525682 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 9/0053 (20130101) A61K 38/06 (20130101) Original (OR) Class A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 304/15001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/6893 (20130101) G01N 2333/46 (20130101) G01N 2333/948 (20130101) G01N 2333/96433 (20130101) G01N 2333/96494 (20130101) G01N 2800/12 (20130101) G01N 2800/7052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335460 | Felber et al. |
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| FUNDED BY |
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| APPLICANT(S) | Novartis AG (Basel, Switzerland); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | NOVARTIS AG (Basel, Switzerland); The United States of America Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Barbara K. Felber (Rockville, Maryland); Sergio Finkielsztein (Newton, Massachusetts); George N. Pavlakis (Bethesda, Maryland); John N. Vournakis (Charleston, South Carolina) |
| ABSTRACT | Described herein are dose escalation regimens for the administration of complexes comprising interleukin-15 (“IL-15”) covalently or noncovalently bound to IL-15 receptor alpha (“IL-15Rα”) to patients in order to enhance IL-15-mediated immune function. In a specific aspect, the dose escalation regimens are useful in the prevention, treatment, and/or management of disorders in which enhancing IL-15-mediated function is beneficial, such as cancer, infectious diseases, immunodeficiencies and lymphopenia. In another specific aspect, the dose escalation regimens are useful for eradicating or reducing HIV in HIV-infected patients. |
| FILED | Tuesday, July 28, 2015 |
| APPL NO | 15/328882 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1793 (20130101) A61K 38/1793 (20130101) A61K 38/2046 (20130101) A61K 38/2086 (20130101) Original (OR) Class A61K 38/2086 (20130101) A61K 39/39558 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335470 | Singh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Pomila Singh (Houston, Texas); Gurpreet Singh (Houston, Texas) |
| ABSTRACT | The present invention is drawn to immunotherapeutic methods to treat tumors/cancers that produce progastrin ectopically or are dependent on progastrin for their growth. Disclosed herein are immunogenic compositions comprising agents that target progastrin, agents that target the progastrin receptor, annexin II, or both. Such a composition may be administered in combination with chemotherapy or to an individual who had been previously subjected to chemotherapy or radiation therapy. The cancers that may be treated using such a composition may include but are not limited to colon cancer, breast cancer, lung cancer or pancreatic cancer. |
| FILED | Monday, December 22, 2014 |
| APPL NO | 14/579220 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/2207 (20130101) A61K 39/0005 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 14/595 (20130101) C07K 16/26 (20130101) C07K 2317/77 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335476 | Thomas et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sunil Thomas (Dickinson, Texas); David H. Walker (Galveston, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Sunil Thomas (Dickinson, Texas); David H. Walker (Galveston, Texas) |
| ABSTRACT | Certain embodiments are direct to a vaccine composition comprising an immunizing amount of an Ehrlichia sonicate, wherein the Ehrlichia sonicate elicits a protective physiologic response. In certain aspects the Ehrlichia is one or more of E. canis, E. chaffeensis, E. muris, E. ruminantium, E. ewingii, and E. ovis. |
| FILED | Wednesday, October 21, 2015 |
| APPL NO | 14/919494 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0233 (20130101) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/55566 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335477 | Galan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Jorge E. Galan (New Haven, Connecticut); Jeongmin Song (Hamden, Connecticut) |
| ABSTRACT | The invention provides compositions and methods for preventing, treating and diagnosing infection by Salmonella enterica serovar typhi (S. typhi) and/or S. paratyphi, i.e., typhoid fever. |
| FILED | Tuesday, May 20, 2014 |
| APPL NO | 14/892237 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 39/0275 (20130101) Original (OR) Class A61K 39/3955 (20130101) A61K 2039/505 (20130101) A61K 2039/55583 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/12 (20130101) Peptides C07K 16/40 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56916 (20130101) G01N 2333/255 (20130101) G01N 2333/916 (20130101) G01N 2333/91142 (20130101) Technologies for Adaptation to Climate Change Y02A 50/484 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335478 | Kinney et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Mahidol University (Nakhon Pathom, Thailand) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Mahidol University (Nakhon Pathom, Thailand) |
| INVENTOR(S) | Richard M. Kinney (Fort Collins, Colorado); Claire Y. H. Kinney (Fort Collins, Colorado); Siritorn Butrapet (Bangkok, Thailand); Duane J. Gubler (St. George, Utah); Natth Bhamarapravati (Bangkok, Thailand) |
| ABSTRACT | Chimeric flaviviruses that are avirulent and immunogenic are provided. The chimeric viruses are constructed to contain amino acid mutations in the nonstructural viral proteins of a flavivirus. Chimeric viruses containing the attenuation-mutated nonstructural genes of the virus are used as a backbone into which the structural genes of a second flavivirus strain are inserted. These chimeric viruses elicit pronounced immunogenicity yet lack the accompanying clinical symptoms of viral disease. The attenuated chimeric viruses are effective as immunogens or vaccines and may be combined in a pharmaceutical composition to confer simultaneous immunity against several strains of pathogenic flaviviruses. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/257430 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 39/295 (20130101) A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) C07K 14/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24121 (20130101) C12N 2770/24122 (20130101) C12N 2770/24134 (20130101) Technologies for Adaptation to Climate Change Y02A 50/39 (20180101) Y02A 50/386 (20180101) Y02A 50/388 (20180101) Y02A 50/394 (20180101) Y02A 50/396 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335491 | Tseng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hsian-Rong Tseng (Los Angeles, California); Hao Wang (Los Angeles, California); Kuan-Ju Chen (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); National Institutes of Health (NIH) (Bethesda, Maryland) |
| INVENTOR(S) | Hsian-Rong Tseng (Los Angeles, California); Hao Wang (Los Angeles, California); Kuan-Ju Chen (Los Angeles, California) |
| ABSTRACT | This invention relates, e.g., to a molecular delivery system comprising A. a substrate having a nanostructured surface region which comprises a plurality of nanostructures and, covalently attached to the substrate, multiple copies of a first member of a binding pair; and B. at least one vector nanoparticle which comprises, encapsulated therein, a molecule of interest, and on its surface, multiple copies of second member of the binding pair. Methods of using the molecular delivery system to deliver a molecule of interest to a cell are also described. |
| FILED | Monday, July 23, 2012 |
| APPL NO | 14/234321 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/54 (20170801) A61K 47/59 (20170801) Original (OR) Class A61K 47/60 (20170801) A61K 47/595 (20170801) A61K 47/6923 (20170801) A61K 47/6925 (20170801) A61K 47/6951 (20170801) A61K 47/6957 (20170801) A61K 48/0008 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335493 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Lily Yang (Atlanta, Georgia); Xiangxue Gao (Lilburn, Georgia) |
| ABSTRACT | This disclosure relates to targeted protease compositions and uses related thereto. In certain embodiments, the disclosure relates to nanoparticles wherein a targeting molecule is linked to the nanoparticle and wherein a catalytic domain of a protease is linked to the nanoparticle. In certain embodiments, the targeting molecule and the catalytic domain are within a single polypeptide sequence. In certain embodiments, the targeting molecule binds a molecule more highly expressed on cancer cells then non-cancerous cells, and the nanoparticles disclosed herein are used for the treatment of cancer by further attaching an anti-cancer agent to the nanoparticle or incorporating an anticancer agent within the nanoparticle. |
| FILED | Monday, December 08, 2014 |
| APPL NO | 15/102600 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) Original (OR) Class A61K 49/0056 (20130101) A61K 49/0065 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/50 (20130101) C12N 9/96 (20130101) Enzymes C12Y 304/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335498 | Elangovan et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Satheesh Elangovan (Iowa City, Iowa); Sheetal Reginald R D'mello (Silver Spring, Maryland); Anh-Vu T Do (Iowa City, Iowa); Liu Hong (Coralville, Iowa); Behnoush Khorsand-Sourkohi (Iowa City, Iowa); Aliasger K Salem (Coralville, Iowa); Michael Kormann (Tübingen, Germany) |
| ABSTRACT | The present disclosure provides compositions and methods useful for tissue engineering including a composition having chemically modified RNA (cmRNA) encapsulated in or complexed with a non-viral delivery vehicle and a biocompatible, bioresorbable scaffold and methods of using the composition to regenerate, for example, bone tissue. |
| FILED | Tuesday, December 29, 2015 |
| APPL NO | 14/983021 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/712 (20130101) A61K 31/7115 (20130101) A61K 38/00 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) A61K 48/0041 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 2300/62 (20130101) A61L 2300/258 (20130101) A61L 2300/414 (20130101) A61L 2430/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335500 | Hanes et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Justin Hanes (Baltimore, Maryland); Jung Soo Suk (Baltimore, Maryland); Panagiotis Mastorakos (Charlottesville, Virginia) |
| ABSTRACT | A major challenge in non-viral gene delivery remains finding a safe and effective delivery system. Colloidally stable non-viral gene vector delivery systems capable of overcoming various biological barriers, are disclosed. The gene vectors are biodegradable, non-toxic and highly tailorable for use in specific applications. The vectors include a mixture of biodegradable copolymers, such as PBAE, and biodegradable polymers conjugated with hydrophilic, neutrally charged polymer, such as PEG. The gene vectors demonstrate broad vector distribution and high transgene delivery in vivo, providing an efficient non-viral gene delivery system for localized therapeutic gene transfer. Methods of using the vectors to overcome biological barriers including mucus gel and extracellular matrix are provided. Methods of formulating the vectors are also provided. |
| FILED | Tuesday, May 12, 2015 |
| APPL NO | 15/310643 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 9/0085 (20130101) A61K 9/5153 (20130101) A61K 47/60 (20170801) A61K 47/593 (20170801) A61K 47/6935 (20170801) A61K 48/00 (20130101) A61K 48/005 (20130101) Original (OR) Class A61K 48/0041 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335501 | Bradbury et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Cornell University (Ithaca, New York) |
| INVENTOR(S) | Michelle S. Bradbury (New York, New York); Barney Yoo (New York, New York); Ulrich Wiesner (Ithaca, New York); Peiming Chen (New York, New York); Kai Ma (Ithaca, New York); Snehal G. Patel (New York, New York); Daniella Karassawa Zanoni (New York, New York) |
| ABSTRACT | Described herein are cyclic peptides, nanoparticles bound with cyclic peptides, and methods for using said cyclic peptides and/or said nanoparticles bound with cyclic peptides for intraoperative nerve tissue imaging. |
| FILED | Tuesday, December 15, 2015 |
| APPL NO | 14/969877 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/4893 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 49/0032 (20130101) A61K 49/0056 (20130101) Original (OR) Class A61K 49/0065 (20130101) A61K 49/0093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335515 | Detamore et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | The University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Michael Detamore (Lawrence, Kansas); Emily Beck (Lawrence, Kansas); Stevin Gehrke (Lawrence, Kansas); Cory Berkland (Lawrence, Kansas) |
| ABSTRACT | An implantable hydrogel precursor composition can include: a cross-linkable polymer matrix that is biocompatible; and a plurality of polymer particles in the cross-linkable polymer matrix. The cross-linkable polymer matrix can include a cross-linkable hyaluronic acid polymer that has cross-linkable functional groups. The hyaluronic acid polymer can be a methacrylated hyaluronic acid polymer. The methacrylated hyaluronic acid polymer can have a molecular weight from about 500 kDa to about 1.8 MDa. The polymer particles can include a cross-linked hyaluronic acid. The cross-linkable polymer matrix having the polymer particles has a yield stress. The cross-linkable polymer matrix having the polymer particles has shape retention at physiological temperatures. The composition can include live cells in the cross-linkable polymer matrix. The composition can include a biologically active agent in the cross-linkable polymer matrix. |
| FILED | Tuesday, October 20, 2015 |
| APPL NO | 14/918229 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/20 (20130101) A61L 27/48 (20130101) Original (OR) Class A61L 27/48 (20130101) A61L 27/50 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/383 (20130101) A61L 27/3817 (20130101) A61L 27/3834 (20130101) A61L 2430/06 (20130101) A61L 2430/32 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) C08L 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335519 | Kaplan et al. |
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| FUNDED BY |
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| APPLICANT(S) | David L. Kaplan (Concord, Massachusetts); Lee W. Tien (Brookline, Massachusetts); Gary G. Leisk (Wilmington, Massachusetts); Tim Jia-Ching Lo (Lungtan, Taiwan); Cinzia Metallo (Somerville, Massachusetts); Fiorenzo Omenetto (Wakefield, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Lee W. Tien (Brookline, Massachusetts); Gary G. Leisk (Wilmington, Massachusetts); Tim Jia-Ching Lo (Lungtan, Taiwan); Cinzia Metallo (Somerville, Massachusetts); Fiorenzo Omenetto (Wakefield, Massachusetts) |
| ABSTRACT | Provided herein relates to implantable devices and systems with dynamic silk coatings. In some embodiments, the dynamic silk coatings can be formed in situ or in vivo. |
| FILED | Friday, April 20, 2012 |
| APPL NO | 14/112078 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0478 (20130101) A61B 5/686 (20130101) A61B 5/4088 (20130101) A61B 5/4094 (20130101) A61B 5/6868 (20130101) A61B 5/6877 (20130101) A61B 2562/125 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/227 (20130101) A61L 27/3604 (20130101) A61L 27/3675 (20130101) A61L 31/10 (20130101) Original (OR) Class A61L 31/14 (20130101) A61L 31/16 (20130101) A61L 31/047 (20130101) A61L 2400/18 (20130101) A61L 2420/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/375 (20130101) A61N 1/0529 (20130101) A61N 1/0541 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335530 | Madhani et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Shalv Madhani (Pittsburgh, Pennsylvania); Brian Joseph Frankowski (Imperial, Pennsylvania); William J. Federspiel (Pittsburgh, Pennsylvania) |
| ABSTRACT | An extracorporeal system for lung assist includes a system housing, which includes a blood flow inlet and a blood flow outlet and a fiber bundle housing movably positioned within the system housing. The fiber bundle housing includes a gas inlet and a gas outlet. A fiber bundle is in operative connection with the fiber bundle housing. The fiber bundle includes a plurality of hollow gas permeable fibers, wherein lumens of the plurality of hollow gas fibers are in fluid connection with the gas inlet at a first end thereof and in fluid connection with the gas outlet as a second end thereof. The system further includes an actuator to impart oscillatory motion to the fiber bundle housing and thereby to the fiber bundle. |
| FILED | Friday, October 07, 2016 |
| APPL NO | 15/288111 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/26 (20130101) A61M 1/1625 (20140204) Original (OR) Class A61M 1/1649 (20140204) A61M 1/1698 (20130101) A61M 2202/0208 (20130101) A61M 2202/0225 (20130101) A61M 2205/3334 (20130101) Separation B01D 63/02 (20130101) B01D 2311/2661 (20130101) B01D 2315/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335590 | Katnani et al. |
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| FUNDED BY |
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| APPLICANT(S) | Husam Katnani (Boston, Massachusetts); Giorgio Bonmassar (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Husam Katnani (Boston, Massachusetts); Giorgio Bonmassar (Boston, Massachusetts) |
| ABSTRACT | A lead for an implanted medical device is disclosed in which the lead is adapted for electrical communication with an electrical signal source and has a distal tip with an electrode. The lead comprises a wire adapted to be placed in electrical communication with electrode. The wire includes: (i) a core comprising a polymeric material, and (ii) a metallic layer surrounding an outer surface of the core. The metallic layer includes a first section having a first thickness and a second section having a second thickness, wherein the first thickness is greater than the second thickness. The lead is substantially transparent to radio frequency waves in clinically-applicable magnetic resonance environments to reduce radio frequency absorption and avoid substantial heating effects. |
| FILED | Thursday, September 10, 2015 |
| APPL NO | 14/850229 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) Original (OR) Class A61N 1/086 (20170801) A61N 1/0534 (20130101) A61N 1/0551 (20130101) A61N 1/0563 (20130101) A61N 1/3718 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336678 | Shockley et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Samantha E. Shockley (Pasadena, California); John C. Hethcox (Pasadena, California); Brian M. Stoltz (San Marino, California) |
| ABSTRACT | The present disclosure provides methods for enantioselective synthesis of acyclic α-quaternary carboxylic acid derivatives via iridium-catalyzed allylic alkylation. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/977638 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/12 (20130101) B01J 31/186 (20130101) B01J 2231/44 (20130101) B01J 2531/827 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 51/08 (20130101) Original (OR) Class C07C 51/08 (20130101) C07C 51/08 (20130101) C07C 51/08 (20130101) C07C 51/08 (20130101) C07C 51/08 (20130101) C07C 57/03 (20130101) C07C 57/03 (20130101) C07C 57/26 (20130101) C07C 57/42 (20130101) C07C 57/60 (20130101) C07C 59/48 (20130101) C07C 67/00 (20130101) C07C 67/00 (20130101) C07C 67/22 (20130101) C07C 69/52 (20130101) C07C 69/65 (20130101) C07C 201/12 (20130101) C07C 201/12 (20130101) C07C 205/57 (20130101) C07C 231/18 (20130101) C07C 231/18 (20130101) C07C 233/09 (20130101) C07C 233/09 (20130101) C07C 253/30 (20130101) C07C 253/30 (20130101) C07C 255/38 (20130101) C07C 2601/14 (20170501) C07C 2601/16 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336713 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents, Acting for and on behalf of, Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, Acting for and on behalf of, Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Peiming Zhang (Gilbert, Arizona); Stuart Lindsay (Phoenix, Arizona); Sovan Biswas (Tempe, Arizona); Suman Sen (Tempe, Arizona) |
| ABSTRACT | Triazole-based molecules, methods of making and using the same are provided. Triazole-based molecules may be used as reading molecules and incorporated into or operatively-linked with electrodes, for example, and used in recognition tunneling systems to identify individual and/or sequences of molecules (e.g., DNA bases, carbohydrates, proteins, peptides, and/or amino-acids). |
| FILED | Friday, February 27, 2015 |
| APPL NO | 15/121669 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 319/12 (20130101) Heterocyclic Compounds C07D 249/10 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3276 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336721 | Jorgensen et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | William L. Jorgensen (Deep River, Connecticut); Pawel Dziedzic (New Haven, Connecticut); Jose Cisneros (New Haven, Connecticut) |
| ABSTRACT | The present disclosure describes biaryl triazole compounds, as well as their compositions and methods of use. The compounds inhibit the activity of macrophage migration inhibitory factor and are useful for the treatment of diseases, e.g., inflammatory diseases and cancer. |
| FILED | Friday, February 12, 2016 |
| APPL NO | 15/550573 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 401/04 (20130101) Original (OR) Class C07D 403/04 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336734 | Mahajan et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| INVENTOR(S) | Nupam P. Mahajan (Tampa, Florida); Kiran N. Mahajan (Tampa, Florida); Nicholas J. Lawrence (Tampa, Florida); Harshani R. Lawrence (Tampa, Florida) |
| ABSTRACT | Described are cancer therapies and anti-cancer compounds. In particular, disclosed are inhibitors of ACK1 tyrosine kinase and their use in the treatment of cancer. Methods of screening for new ACK1 tyrosine kinase inhibitors are also disclosed. In specific example, compound having Formula I are disclosed. |
| FILED | Tuesday, August 02, 2016 |
| APPL NO | 15/748214 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 239/48 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) Original (OR) Class C07D 405/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336737 | Sarlah et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | David Sarlah (Champaign, Illinois); Lucas William Hernandez (Urbana, Illinois); Jola Pospech (Rostock, Germany) |
| ABSTRACT | Described herein is the development of an arenophile-mediated, nickel-catalyzed dearomative trans-1,2-carboamination protocol. A range of readily available aromatic compounds was converted to the corresponding dienes using Grignard reagents as nucleophiles. This strategy provided products with exclusive trans-selectivity and high enantioselectivity was observed in case of benzene and naphthalene. The utility of this methodology was showcased by controlled and stereoselective preparation of small, functionalized molecules. A concise synthesis of (+)-pancratistatin and (+)-7-deoxypancratistatin from benzene using an enantioselective, dearomative carboamination strategy has been achieved. This approach, in combination with the judicious choice of subsequent olefin-type difunctionalization reactions, permits rapid and controlled access to a hexasubstituted core. Finally, minimal use of intermediary steps as well as direct, late stage C-7 hydroxylation provides both natural products in six and seven operations. |
| FILED | Monday, June 18, 2018 |
| APPL NO | 16/011178 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2295 (20130101) B01J 2231/321 (20130101) B01J 2523/842 (20130101) B01J 2523/847 (20130101) Heterocyclic Compounds C07D 407/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336757 | Chiosis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gabriela Chiosis (New York, New York); Paul Greengard (New York, New York); Fei Dou (Nanjing, China PRC); Wenjie Luo (Hopatcong, New Jersey); Huazhong He (New York, New York); Danuta Zatorska (Ericeira, Portugal) |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York); The Rockefeller University (New York, New York) |
| INVENTOR(S) | Gabriela Chiosis (New York, New York); Paul Greengard (New York, New York); Fei Dou (Nanjing, China PRC); Wenjie Luo (Hopatcong, New Jersey); Huazhong He (New York, New York); Danuta Zatorska (Ericeira, Portugal) |
| ABSTRACT | Treatment of neurodegenerative diseases is achieved using small molecule purine scaffold compounds that inhibit Hsp90 and that possess the ability to cross the blood-brain barrier or are other wise delivered to the brain. |
| FILED | Monday, July 02, 2007 |
| APPL NO | 12/307063 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) Heterocyclic Compounds C07D 473/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336768 | Cuny et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yuma Therapeutics, Inc. (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Yuma Therapeutics, Inc. (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Gregory D. Cuny (Houston, Texas); Marcie A. Glicksman (Boston, Massachusetts); Kevin J. Hodgetts (Framingham, Massachusetts); Steven L. Mathieu (Somerville, Massachusetts); Yukari Y. Perrella (Cambridge, Massachusetts); Vincent Darmency (Bougy Villars, Switzerland); Hrvoje Lusic (Boston, Massachusetts) |
| ABSTRACT | The present invention relates to 2-amino-4-arylpyrimidine and 2-amino-4-aryltriazine compounds as inhibitors of heat shock protein 90 family of chaperone proteins. The invention also features pharmaceutical compositions and kits that include the compounds and compositions of the invention. The invention further relates to the medical use of these compounds and compositions for the treatment of a disorder in a subject. For example, the disorder is a neurodegenerative disease. |
| FILED | Monday, June 15, 2015 |
| APPL NO | 15/317999 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 239/42 (20130101) C07D 239/70 (20130101) C07D 239/84 (20130101) C07D 251/16 (20130101) C07D 251/22 (20130101) C07D 405/04 (20130101) C07D 405/10 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 495/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336786 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Zhijian Chen (Dallas, Texas); Lijun Sun (Dallas, Texas); Jiaxi Wu (Dallas, Texas); Heping Shi (Dallas, Texas); Chuo Chen (Dallas, Texas) |
| ABSTRACT | Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2′3-cGAMP, 2′2-cGAMP, 3′2′-cGAMP and 3′3′-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies and diagnostics. |
| FILED | Monday, December 16, 2013 |
| APPL NO | 14/653586 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7084 (20130101) A61K 39/39 (20130101) A61K 2039/55511 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/25 (20130101) C12Q 1/6876 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/573 (20130101) G01N 2333/9015 (20130101) G01N 2333/9125 (20130101) G01N 2400/00 (20130101) G01N 2500/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336790 | Belfort et al. |
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| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Georges Belfort (Slingerlands, New York); C. Seth Pearson (Albany, New York); Brian Murray (Troy, New York); Pankaj Sakharam Karande (Troy, Michigan); Jun Ha Kwak (Troy, New York); Kathleen A. McDonough (Albany, New York); Zachary Andrew Kloos (New Haven, Connecticut) |
| ABSTRACT | Disclosed herein are novel anti-microbial peptides with inhibitory activity against M. tuberculosis and streptococcus bacteria. Additionally, a method for designing novel anti-microbial peptides is disclosed. |
| FILED | Thursday, September 08, 2016 |
| APPL NO | 15/259942 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/38 (20130101) A01N 63/02 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/10 (20130101) A61K 45/06 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336796 | Simon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia) |
| ASSIGNEE(S) | MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia) |
| INVENTOR(S) | Roger P. Simon (Atlanta, Georgia); Zhigang Xiong (Atlanta, Georgia) |
| ABSTRACT | A system, including methods and compositions, for treatment of ischemia. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/638655 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/439 (20130101) A61K 31/498 (20130101) A61K 31/4418 (20130101) A61K 31/4965 (20130101) A61K 38/16 (20130101) A61K 38/17 (20130101) A61K 38/1767 (20130101) A61K 45/06 (20130101) Peptides C07K 14/43518 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336804 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Tong Zhang (Lebanon, New Hampshire); Charles L. Sentman (West Lebanon, New Hampshire) |
| ABSTRACT | The present invention relates to chimeric immune receptor molecules for reducing or eliminating tumors. The chimeric receptors are composed a C-type lectin-like natural killer cell receptor, or a protein associated therewith, fused to an immune signaling receptor containing an immunoreceptor tyrosine-based activation motif. Methods for using the chimeric receptors are further provided. |
| FILED | Tuesday, January 20, 2015 |
| APPL NO | 14/600799 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/10 (20130101) A61K 45/06 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 14/715 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336997 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); Kevin Michael Esvelt (Cambridge, Massachusetts); Jacob Charles Carlson (Somerville, Massachusetts) |
| ABSTRACT | The invention provides systems, methods, reagents, apparatuses, vectors, and host cells for the continuous evolution of nucleic acids. For example, a lagoon is provided in which a population of viral vectors comprising a gene of interest replicates in a stream of host cells, wherein the viral vectors lack a gene encoding a protein required for the generation of infectious viral particles, and wherein that gene is expressed in the host cells under the control of a conditional promoter, the activity of which depends on a function of the gene of interest to be evolved. Some aspects of this invention provide evolved products obtained from continuous evolution procedures described herein. Kits containing materials for continuous evolution are also provided. |
| FILED | Tuesday, June 21, 2016 |
| APPL NO | 15/188627 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/70 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 15/1058 (20130101) Original (OR) Class C12N 2795/14121 (20130101) C12N 2795/14152 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/06 (20130101) C40B 60/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336999 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Zymergen Inc. (Emeryville, California) |
| ASSIGNEE(S) | Zymergen Inc. (Emeryville, California) |
| INVENTOR(S) | Oliver Liu (San Francisco, California); Jeffrey Hoon Kim (Berkeley, California) |
| ABSTRACT | The disclosure provides compositions and methods for producing natural products in microorganisms that are otherwise unexpressed, poorly expressed or poorly transcribed. In particular aspects, the disclosure provides compositions and methods for activating a silent gene or gene cluster with a bacteriophage and/or Streptomyces Antibiotic Regulatory Protein (SARP) transcription factor. |
| FILED | Friday, May 27, 2016 |
| APPL NO | 15/167224 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/63 (20130101) C12N 15/76 (20130101) C12N 15/1072 (20130101) Original (OR) Class C12N 2795/10042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337015 | Lutz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Gordon J. Lutz (Kennett Square, Pennsylvania); Melanie K. Tallent (Kennett Square, Pennsylvania); Nicole Michele Lykens (Woodbury, New Jersey) |
| ABSTRACT | The present invention encompasses a class of compounds known as splice modulating oligonucleotides (SMOs) that modulate pre-mRNA splicing, thereby affecting expression and functionality of a specific protein in a cell. The present invention further provides compositions and methods for modulating pre-mRNA splicing using a SMO of the invention to abrogate disease-causing mutations in a protein. Accordingly, the present invention provides compositions and methods of treating a subject at risk of, susceptible to, or having a disease, disorder, or condition associated with aberrant or unwanted target pre-mRNA expression or activity. |
| FILED | Monday, July 30, 2018 |
| APPL NO | 16/049109 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/1135 (20130101) C12N 15/1137 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337019 | Wu |
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| FUNDED BY |
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| APPLICANT(S) | Intact Genomics, Inc (Saint Louis, Missouri) |
| ASSIGNEE(S) | INTACT GENOMICS, INC. (Saint Louis, Missouri) |
| INVENTOR(S) | Chengcang Charles Wu (Saint Louis, Missouri) |
| ABSTRACT | Fungal artificial chromosome (FAC) vectors are disclosed. A vector can be replicated in a bacterial or a fungal host, and can comprise an insert of heterologous DNA up to about 500 kilobases. A vector can be used for cloning and expressing a secondary metabolite (SM) gene cluster. An insert sequence can be modified by homologous recombination. A vector can be a plasmid comprising bacterial and fungal origins of replication, as well as bacterial and fungal selection marker genes. Also disclosed are vectors that can be integrated into a fungal genome, and dual function vectors which can be replicated in a bacterial or a fungal host and can also be integrated into a fungal genome. Also disclosed are methods of generating plasmid libraries including vectors comprising intact SM gene clusters. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/143493 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/52 (20130101) C12N 15/69 (20130101) C12N 15/80 (20130101) Original (OR) Class C12N 15/1082 (20130101) C12N 15/1082 (20130101) C12N 15/1093 (20130101) C12N 2800/20 (20130101) C12N 2800/70 (20130101) C12N 2820/002 (20130101) C12N 2820/10 (20130101) C12N 2820/55 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2525/191 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337051 | Doudna et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Mitchell Ray O'Connell (Oakland, California); Alexandra East-Seletsky (San Francisco, California); Spencer Charles Knight (Berkeley, California); James Harrison Doudna Cate (Berkeley, California) |
| ABSTRACT | The present disclosure provides methods for detecting a single-stranded target RNA. The present disclosure provides methods of cleaving a precursor C2c2 guide RNA array into two or more C2c2 guide RNAs. The present disclosure provides a kit for detecting a target RNA in a sample. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/467922 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6823 (20130101) Original (OR) Class C12Q 1/6823 (20130101) C12Q 2521/327 (20130101) Technologies for Adaptation to Climate Change Y02A 50/53 (20180101) Y02A 50/54 (20180101) Y02A 50/57 (20180101) Y02A 50/58 (20180101) Y02A 50/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337053 | Rao et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); THE UNTTED STATES OF AMERICA AS REPRESENTED, BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia) |
| INVENTOR(S) | Anjana Rao (La Jolla, California); Mamta Tahiliani (New York, New York); Kian Peng Koh (Jamaica Plain, Massachusetts); Suneet Agarwal (Belmont, Massachusetts); Aravind Iyer (Bethesda, Maryland) |
| ABSTRACT | The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes being capable of converting the cytosine nucleotide 5-methylcytosine into 5-hydroxymethylcytosine by hydroxylation. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/012280 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0607 (20130101) C12N 5/0637 (20130101) C12N 5/0696 (20130101) C12N 9/0071 (20130101) C12N 15/873 (20130101) C12N 2501/15 (20130101) C12N 2501/70 (20130101) C12N 2501/71 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/606 (20130101) C12N 2501/999 (20130101) C12N 2506/1307 (20130101) C12N 2506/1353 (20130101) C12N 2510/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6869 (20130101) C12Q 1/6886 (20130101) C12Q 2521/531 (20130101) C12Q 2522/10 (20130101) C12Q 2537/164 (20130101) C12Q 2600/154 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5308 (20130101) G01N 33/57426 (20130101) G01N 33/57484 (20130101) G01N 33/57496 (20130101) G01N 2500/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337059 | Esfandyarpour et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Hesaam Esfandyarpour (Los Altos, California); Mostafa Ronaghi (Los Altos Hills, California) |
| ABSTRACT | The present method involves sequencing by synthesis in which a template strand having an attached primer is immobilized in a small volume reaction mixture. In one embodiment, the reaction mixture is in contact with a sensitive heat sensor, which detects the heat of reaction from incorporation of a complementary base (dNTP) in the presence of appropriate reagents (DNA polymerase, and polymerase reaction buffer). Alternatively, or in addition, a change in pH resulting from the incorporation of nucleotides in the DNA polymerase reaction is measured. A device is provided having delivery channels for appropriate reagents, including dNTPs, which may be delivered sequentially or in a mixture. Preferably, the dNTPs are added in a predetermined sequence, and the dNTP is incorporated or not depending on the template sequence. |
| FILED | Monday, September 21, 2015 |
| APPL NO | 14/860553 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2527/101 (20130101) C12Q 2527/119 (20130101) C12Q 2565/301 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337062 | Giresi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Paul Giresi (Palo Alto, California); Jason D. Buenrostro (Redwood City, California); Howard Y. Chang (Stanford, California); William J. Greenleaf (Menlo Park, California) |
| ABSTRACT | Provided herein is a method for analyzing polynucleotides such as genomic DNA. In certain embodiments, the method comprises: (a) treating chromatin isolated from a population of cells with an insertional enzyme complex to produce tagged fragments of genomic DNA; (b) sequencing a portion of the tagged fragments to produce a plurality of sequence reads; and (c) making an epigenetic map of a region of the genome of the cells by mapping information obtained from the sequence reads to the region. A kit for performing the method is also provided. |
| FILED | Monday, October 15, 2018 |
| APPL NO | 16/160719 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337065 | Tavazoie et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | THE ROCKEFELLER UNIVERSITY (New York, New York) |
| INVENTOR(S) | Sohail Tavazoie (New York, New York); Hani Goodarzi (New York, New York) |
| ABSTRACT | In one embodiment, the present invention relates to a method for optimizing cell-type specific protein expression. In another embodiment, the present invention relates to a method for creating a tRNA profile of a cell. |
| FILED | Thursday, April 13, 2017 |
| APPL NO | 15/487192 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2521/327 (20130101) C12Q 2521/501 (20130101) C12Q 2535/122 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337995 | Yi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOSTON MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | BOSTON MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Ji Yi (Brookline, Massachusetts) |
| ABSTRACT | A method for constructing a three-dimensional image of a sample includes producing electromagnetic radiation and directing the produced electromagnetic radiation such that it is incident on the sample at an oblique angle. The incident electromagnetic radiation is scanned in discrete increments to a plurality of discrete locations along a first direction, and at each discrete location, scanned along a second direction orthogonal to the first direction. The sample reflects a first portion of the incident electromagnetic radiation and absorbs a second portion of the incident electromagnetic radiation, and emits electromagnetic radiation responsive to the absorption. A plurality of cross-sectional images is produced from the reflected electromagnetic radiation and the emitted electromagnetic radiation, and each cross-sectional image is modified to compensate for the oblique angle. The modified cross-sectional images are then combined to create a three-dimensional image of the sample. |
| FILED | Monday, June 11, 2018 |
| APPL NO | 16/005246 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/0071 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02091 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0208 (20130101) G01J 3/4406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) G01N 21/4795 (20130101) G01N 21/6402 (20130101) G01N 21/6458 (20130101) Original (OR) Class G01N 2021/1785 (20130101) G01N 2021/1787 (20130101) Optical Elements, Systems, or Apparatus G02B 26/085 (20130101) G02B 26/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338052 | Chekmenev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Eduard Y. Chekmenev (Brentwood, Tennessee); Roman V. Shchepin (Nashville, Tennessee) |
| ABSTRACT | Methods of detecting a sulfur-containing compound in a sample are described, for example using NMR-SABRE hyperpolarization of the sulfur-containing compounds in the sample. The methods can comprise, for example, contacting a sample comprising a sulfur-containing compound with parahydrogen and a catalyst to form a mixture. A spin order can be transferred from the parahydrogen to the sulfur-containing compound thereby hyperpolarizing the sulfur-containing compound during a temporary association of the parahydrogen, the sulfur-containing compound, and the catalyst. The methods can further comprise, for example, performing an NMR measurement on the mixture comprising the hyperpolarized sulfur-containing compound to detect the hyperpolarized sulfur-containing compound (e.g., from the hyperpolarized NMR signals. In some examples, the methods described herein can be used for detecting a sulfur-containing contaminant in a fuel. |
| FILED | Tuesday, November 29, 2016 |
| APPL NO | 15/362846 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/08 (20130101) G01N 33/287 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/282 (20130101) G01R 33/307 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338070 | Ervin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ELECTRONIC BIO SCIENCES, INC. (San Diego, California) |
| ASSIGNEE(S) | Electronic BioSciences, Inc. (San Diego, California) |
| INVENTOR(S) | Eric Ervin (Salt Lake City, Utah); Anna E. P. Schibel (Snoqualmie, Washington) |
| ABSTRACT | Provided herein is a cell-free assay device, sometimes comprising a lipid bilayer and an endopeptidase assay component, for characterizing a pore forming protein. In some embodiments provided herein is an apparatus comprising a pressure system for characterizing an interaction. Also, provided herein are methods for using a cell-free assay device to characterize a pore forming protein and/or a test substance. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 15/498864 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/573 (20130101) Original (OR) Class G01N 33/6872 (20130101) G01N 33/48721 (20130101) G01N 2333/952 (20130101) G01N 2500/20 (20130101) G01N 2800/709 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338071 | Hahn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Stephen M. Hahn (Glen Mills, Pennsylvania); Jay F. Dorsey (Media, Pennsylvania); Gary D. Kao (Wynnewood, Pennsylvania); Emigdio Reyes (Philadelphia, Pennsylvania) |
| ABSTRACT | A repeatable method for detecting circulating tumor cells in vitro is provided. The method involves combining a test sample from a patient suspected of having circulating tumor cells, and a non-lytic adenoviral system, and culture media for the cells. The adenoviral system utilizes (i) a first replication-defective adenoviral particle in which an expression cassette is packaged, said expression cassette comprising an adenoviral 5′ and 3′ ITRs and a tumor-specific promoter; and (ii) a coding sequence for a reporter protein which is expressed in the presence of circulating tumor cells, and an adenoviral 3′ ITR. The test sample and the non-lytic adenoviral system are incubated for a sufficient time to permit expression of the reporter protein, and measuring reporter protein expression in the test samples, whereby presence of reporter expression indicates the presence of circulating tumor cells in the sample. Because the system is non-lytic, the testing can be repeated on the cells which remain viable in culture. Also provided is a method for enriching test samples having circulating tumor cells and a microfluidics device suitable for CTC-specification identification and enumeration. |
| FILED | Tuesday, November 14, 2017 |
| APPL NO | 15/812105 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2400/086 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/6069 (20130101) G01N 30/6095 (20130101) G01N 33/574 (20130101) Original (OR) Class G01N 33/54366 (20130101) G01N 2030/524 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338076 | Speicher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| INVENTOR(S) | David W. Speicher (Berwyn, Pennsylvania); Hsin Yao Tang (Media, Pennsylvania); Lynn A. Beer (Medford, New Jersey) |
| ABSTRACT | A diagnostic reagent or device comprises at least one ligand capable of specifically complexing with, binding to, or quantitatively detecting or identifying the biomarker chloride intracellular channel protein 4 (CLIC4) or an isoform, pro-form, modified molecular form including posttranslational modification, or unique peptide fragment or nucleic acid fragment thereof. An alternative diagnostic reagent or device comprises ligand or ligands capable of specifically complexing with, binding to, or quantitatively detecting or identifying multiple tropomyosin biomarkers. Optionally, such reagent or device includes a signaling molecule and/or a substrate on which the ligand is immobilized. Other reagents and methods of diagnosing ovarian cancer include use of CLIC4 ligands and/or multiple tropomyosin ligands with an additional ovarian cancer biomarker. For example, CLIC4 combined with one or more of CLIC1 and/or one or multiple members of the tropomyosin family, e.g., TPM1, TPM2, TPM3 or TPM4, and further optionally including CTSD-30 kDa and/or PRDX-6, among other ovarian cancer biomarkers can form a characteristic diagnostic pattern or profile of expression that is diagnostic of the disease. Still other embodiments are described. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/884691 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 16/3069 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) C40B 40/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6887 (20130101) G01N 33/57449 (20130101) Original (OR) Class G01N 2333/4712 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338079 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEWOMICS INC. (Emeryville, California) |
| ASSIGNEE(S) | NEWOMICS INC. (Berkeley, California) |
| INVENTOR(S) | Daojing Wang (Moraga, California); Pan Mao (Milpitas, California) |
| ABSTRACT | The present disclosure provided methods and systems for diagnosing diseases and monitoring their progression and therapeutic responses by detecting a presence or absence, or an increase or decrease, of one or more substances in a sample. |
| FILED | Wednesday, July 06, 2016 |
| APPL NO | 15/203666 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 2200/10 (20130101) B01L 2200/12 (20130101) B01L 2300/0627 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) B01L 2300/0874 (20130101) B01L 2300/0887 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 30/72 (20130101) G01N 30/6095 (20130101) G01N 30/7266 (20130101) G01N 33/66 (20130101) G01N 33/68 (20130101) G01N 33/92 (20130101) G01N 33/723 (20130101) G01N 33/726 (20130101) G01N 33/6848 (20130101) Original (OR) Class G01N 33/6893 (20130101) G01N 2570/00 (20130101) G01N 2800/042 (20130101) G01N 2800/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338173 | Kolandaivelu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Aravindan Kolandaivelu (Baltimore, Maryland); Henry Halperin (Baltimore, Maryland) |
| ABSTRACT | The present invention is directed to a system and method for reducing large magnetic artifact susceptibility in magnetic resonance imaging. The present invention is used to maximize cancellation of the magnetic field distortion cremated when objects with high variations in magnetic susceptibility are placed in a uniform magnetic field. Particularly, the present invention reduces the magnetic resonance imaging artifact produced by pacemakers and internal cardiac defibrillators in order to maximize the diagnostic image quality in the region surrounding these devices. |
| FILED | Thursday, May 22, 2014 |
| APPL NO | 14/892390 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/3875 (20130101) Original (OR) Class G01R 33/56536 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338174 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior Univesity (Palo Alto, California) |
| INVENTOR(S) | Tao Zhang (Stanford, California); Yuxin Chen (Stanford, California); John M. Pauly (Stanford, California); Shreyas S. Vasanawala (Stanford, California) |
| ABSTRACT | A method for creating a first MRI image and a second MRI image is provided. A first echo is read out. A second echo is read out. The first echo readout is used to generate a first image set, with each image pixel being a first linear combination of the first species and the second species. The second echo readout is used to generate a second image set, with each image pixel being a second linear combination of the first species and the second species. The first image set and second image set are combined to obtain a first combined image containing only the first species and a second combined image containing only the second species, comprising combining the first image set and the second image set to generate two pairs of solutions and using a mathematical optimization to choose a correct pair of solutions. |
| FILED | Tuesday, November 15, 2016 |
| APPL NO | 15/352420 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4828 (20130101) Original (OR) Class G01R 33/5601 (20130101) G01R 33/5611 (20130101) G01R 33/56308 (20130101) G01R 33/56325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338178 | Liang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Zhi-Pei Liang (Champaign, Illinois); Fan Lam (Urbana, Illinois); Chao Ma (Charlestown, Massachusetts) |
| ABSTRACT | Various embodiments accelerate high-resolution magnetic resonance spectroscopic imaging (MRSI). Various embodiments are built on a low-dimensional subspace model exploiting the partial separability of high-dimensional MRSI signals. For two and three dimensional MRSI with one spectral dimension, various embodiments sparsely sample the corresponding (k,t)-space in two complementary data sets, one with dense temporal sampling and high signal-to-noise ratio but limited k-space coverage and the other with sparse temporal sampling but extended k-space coverage. The reconstruction is then done by estimating a set of temporal/spectral basis functions and the corresponding spatial coefficients from these two data sets. The imaging technique of various embodiments can be used for high-resolution MRSI of different nuclei. |
| FILED | Monday, January 11, 2016 |
| APPL NO | 14/992498 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/485 (20130101) G01R 33/561 (20130101) Original (OR) Class G01R 33/5616 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338180 | McMillan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Alan B. McMillan (Madison, Wisconsin); Hyungseok Jang (Madison, Wisconsin) |
| ABSTRACT | A system and method for determining an actual gradient field generated by a magnetic resonance imaging (MRI) system when controlled to produce a prescribed gradient field is provided. The techniques include using the prescribed gradient field, controlling the MRI system to perform a phase encoding including a gradient that is scaled along each direction desired to be measured over a selected number of encoding times and acquiring one-dimensional (1D) data using a prescribed k-space trajectory during the phase encoding. The 1D data is used to determine scaling factors between encoding times that correlate to actual k-space trajectories achieved when controlling the gradient coils to perform the phase encoding based on the desired gradient field and a report is generated that provides a measure of the actual gradient field generated when controlling the MRI system to produce the prescribed gradient field. |
| FILED | Monday, October 12, 2015 |
| APPL NO | 14/881093 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/243 (20130101) G01R 33/4816 (20130101) G01R 33/4824 (20130101) G01R 33/56572 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339648 | Stringfield et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| INVENTOR(S) | Olya Stringfield (Tampa, Florida); Robert J. Gillies (Tampa, Florida) |
| ABSTRACT | Disclosed are methods for quantitatively predicting the severity of a tumor in a subject. In some embodiments, the methods further comprise selecting a course of therapy for the subject. In some embodiments, the tumor comprises is non-small cell lung cancer. |
| FILED | Tuesday, January 21, 2014 |
| APPL NO | 14/761688 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/046 (20130101) G01N 2223/419 (20130101) Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/64 (20170101) G06T 2207/10081 (20130101) G06T 2207/20216 (20130101) G06T 2207/30061 (20130101) G06T 2207/30064 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339653 | Gillies et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); Stichting Maastricht Radiation Oncology ‘Maastro Clinic’ (Maastricht, Netherlands) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); Stichting Maastricht Radiation Oncology ‘Maastro Clinic’ (Maastricht, Netherlands) |
| INVENTOR(S) | Robert J. Gillies (Tampa, Florida); Steven A. Eschrich (Lakeland, Florida); Robert A. Gatenby (Tampa, Florida); Philippe Lambin (Bousval-Genappe, Belgium); Andreas L. A. J. Dekker (Maastricht, Netherlands); Sandy A. Napel (Menlo Park, California); Sylvia K. Plevritis (Los Altos Hills, California); Daniel L. Rubin (Stanford, California) |
| ABSTRACT | An example method for analyzing quantitative information obtained from radiological images includes identifying a ROI or a VOI in a radiological image, segmenting the ROI or the VOI from the radiological image and extracting quantitative features that describe the ROI or the VOI. The method also includes creating a radiological image record including the quantitative features, imaging parameters of the radiological image and clinical parameters and storing the radiological image record in a data structure containing a plurality of radiological image records. In addition, the method includes receiving a request with the patient's radiological image or information related thereto, analyzing the data structure to determine a statistical relationship between the request and the radiological image records and generating a patient report with a diagnosis, a prognosis or a recommended treatment regimen for the patient's disease based on a result of analyzing the data structure. |
| FILED | Monday, July 31, 2017 |
| APPL NO | 15/664530 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/7271 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/463 (20130101) A61B 6/469 (20130101) A61B 6/5211 (20130101) A61B 6/5217 (20130101) Electric Digital Data Processing G06F 19/321 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/46 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10116 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340972 | Calhoun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Benton H. Calhoun (Charlottesville, Virginia); Yousef Shakhsheer (Charlottesville, Virginia); Yanqing Zhang (Charlottesville, Virginia); Alicia Klinefelter (Charlottesville, Virginia); David D. Wentzloff (Ann Arbor, Michigan); Nathan E. Roberts (Ann Arbor, Michigan); Seunghyun Oh (Jangdaedong Daejeon, South Korea) |
| ABSTRACT | An apparatus comprises a system on a chip (SoC). In some embodiments, the SoC includes a power supply circuit, a power management circuit operatively coupled to the power supply circuit, a first wireless communications circuit and a second wireless communications circuit. The first wireless communications circuit is configured to receive an RF signal and is operatively coupled to the power supply circuit and the power management circuit. The first wireless communications circuit has a net radio frequency (RF) power gain no more than unity before at least one of downconversion of the RF signal or detection of the RF signal. The second wireless communications circuit is operatively coupled to the power supply circuit and the power management circuit. |
| FILED | Monday, August 07, 2017 |
| APPL NO | 15/670386 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Transmission H04B 1/406 (20130101) Original (OR) Class H04B 1/1607 (20130101) Wireless Communication Networks H04W 4/70 (20180201) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 70/00 (20180101) Y02D 70/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10341640 | Shechtman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Yoav Shechtman (Santa Clara, California); William E. Moerner (Stanford, California); Lucien Weiss (Los Angeles, California) |
| ABSTRACT | Among other aspects, various embodiments include encoding wavelength-based characteristics, in addition to three-dimensional positions, of a plurality of objects of a plurality of different wavelengths directly in an image of the objects. |
| FILED | Monday, April 11, 2016 |
| APPL NO | 15/096127 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0028 (20130101) G02B 21/0032 (20130101) G02B 21/0056 (20130101) G02B 21/0064 (20130101) G02B 26/06 (20130101) Pictorial Communication, e.g Television H04N 13/161 (20180501) H04N 13/214 (20180501) H04N 13/218 (20180501) Original (OR) Class H04N 13/271 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE47475 | Cook et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WiSys Technology Foundation, Inc. (Madison, Wisconsin) |
| ASSIGNEE(S) | WISYS TECHNOLOGY FOUNDATION, INC. (Madison, Wisconsin) |
| INVENTOR(S) | James M. Cook (Whitefish Bay, Wisconsin); Shengming Huang (Fremont, California); Rahul Edwankar (Phoenixville, Pennsylvania); Ojas A. Namjoshi (Cary, North Carolina); Zhi-Jian Wang (Fremont, California); Qi Huang (Camarillo, California); Xiaohui He (San Diego, California); Xiaoyan Li (Sunnyvale, California); Jianming Yu (Plainsboro, New Jersey); Dongmei Han (Houston, Texas) |
| ABSTRACT | In preferred embodiments, the present invention provides methods of treatment and pharmaceutical compositions for the suppression, alleviation and prevention of the often chronic, severe and debilitating pain that can accompany inflammatory diseases and neuropathic insults, pain that is often unresponsive to conventional analgesic treatment. The preferred embodiments of the present invention further relate to methods of treatment and pharmaceutical compositions using benzodiazepine derivatives that provide suppression, alleviation and prevention of neuropathic pain, migraine-related pain and inflammatory pain with reduced sedative and ataxic side effects. |
| FILED | Friday, September 16, 2016 |
| APPL NO | 15/267953 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Heterocyclic Compounds C07D 243/12 (20130101) Original (OR) Class C07D 243/20 (20130101) C07D 243/24 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 487/06 (20130101) C07D 495/04 (20130101) C07D 498/04 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10335024 | Rentschler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Mark Rentschler (Boulder, Colorado); Shane Farritor (Lincoln, Nebraska) |
| ABSTRACT | The various embodiments disclosed herein relate to procedural space maintenance devices, medical device positioning devices, and devices that provide both procedural space maintenance and device positioning. Further embodiments relate to medical device insertion and/or retraction devices. |
| FILED | Monday, February 08, 2016 |
| APPL NO | 15/018530 |
| ART UNIT | 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/32 (20130101) A61B 1/3132 (20130101) Original (OR) Class A61B 17/0218 (20130101) A61B 17/0281 (20130101) A61B 17/3468 (20130101) A61B 34/30 (20160201) A61B 34/72 (20160201) A61B 34/73 (20160201) A61B 90/50 (20160201) A61B 2017/0042 (20130101) A61B 2017/0225 (20130101) A61B 2017/00283 (20130101) A61B 2017/00292 (20130101) A61B 2017/00345 (20130101) A61B 2017/00349 (20130101) A61B 2017/00557 (20130101) A61B 2017/00876 (20130101) A61B 2034/301 (20160201) A61B 2034/302 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335368 | Fabiilli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Mario L. Fabiilli (Plymouth, Michigan); Christopher Wilson (Ann Arbor, Michigan); Frederic Padilla (Ann Arbor, Michigan); Francisco Martin-Saavedra (Ann Arbor, Michigan) |
| ABSTRACT | The present invention is directed to compositions and methods for delivering a tissue scaffold comprising ultrasound-triggerable agents to an individual. |
| FILED | Friday, February 26, 2016 |
| APPL NO | 15/055263 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) A61K 9/0014 (20130101) A61K 9/0024 (20130101) A61K 9/107 (20130101) A61K 9/113 (20130101) A61K 9/1075 (20130101) Original (OR) Class A61K 35/00 (20130101) A61K 38/363 (20130101) A61K 38/1825 (20130101) A61K 41/0028 (20130101) A61K 47/06 (20130101) A61K 47/10 (20130101) A61K 47/24 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/225 (20130101) A61L 27/227 (20130101) A61L 27/3804 (20130101) A61L 2300/62 (20130101) A61L 2300/252 (20130101) A61L 2300/414 (20130101) A61L 2300/418 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335465 | Harvey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Edgewood Chemical Biological Center (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Steven P Harvey (Lutherville, Maryland); Melissa M Dixon (Abingdon, Maryland); Mark A Guelta (White Marsh, Maryland); Leslie R McMahon (Aberdeen, Maryland) |
| ABSTRACT | The invention is directed toward mutant, non-wild-type organophosphorus acid anhydrolase enzymes having three site mutations, methods of production, and methods of use to effectively degrade toxic organophosphorus compounds, most preferably GP (2,2′-dimethylcyclopentyl methylphosphonofluoridate). |
| FILED | Friday, January 26, 2018 |
| APPL NO | 15/880747 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) Original (OR) Class Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/02 (20130101) A62D 2101/02 (20130101) A62D 2101/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335905 | Hanson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Russell B. Hanson (Jupiter, Florida) |
| ABSTRACT | An iso-grid composite component according to an exemplary aspect of the present disclosure includes a spacer transverse to a uni-tape ply bundle, the spacer interrupted by the uni-tape ply bundle. |
| FILED | Tuesday, September 12, 2017 |
| APPL NO | 15/701475 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/04 (20130101) Original (OR) Class Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/30 (20130101) B29C 70/085 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 28/005 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) Y10T 428/24612 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336042 | Majidi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Carmel Majidi (Pittsburgh, Pennsylvania); Wanliang Shan (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein is a composite comprising a conductive elastomer and an isolating elastomer. When a current is passed through the conductive elastomer, its tensile modulus decreases as the elastomer heats from internal Joule heating, changing the rigidity of the composite. When the current is no longer present, the elastomer cools and the rigidity of the composite returns to its original state. |
| FILED | Thursday, February 02, 2017 |
| APPL NO | 15/423551 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/04 (20130101) B32B 27/08 (20130101) Original (OR) Class B32B 27/20 (20130101) B32B 27/32 (20130101) B32B 27/283 (20130101) B32B 2250/02 (20130101) B32B 2250/24 (20130101) B32B 2250/40 (20130101) B32B 2264/105 (20130101) B32B 2264/108 (20130101) B32B 2274/00 (20130101) B32B 2307/30 (20130101) B32B 2307/51 (20130101) B32B 2307/54 (20130101) B32B 2307/202 (20130101) B32B 2307/206 (20130101) B32B 2457/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336055 | Das et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Suman Das (Atlanta, Georgia); Dajun Yuan (San Diego, California); Anirudh Rudraraju (Hillsboro, Oregon); Paul Cilino (Atlanta, Georgia) |
| ABSTRACT | Systems and methods for fabricating three-dimensional objects. The system includes an optical imaging system providing a light source; a photosensitive medium adapted to change states upon exposure to a portion of the light source from the optical imaging system; a control system for controlling movement of the optical imaging system, wherein the optical imaging system moves continuously above the photosensitive medium. The method includes moving a maskless optical imaging system providing the light beam in a continuous sequence; presenting the light beam on a portion of the photosensitive medium; lowering a plate upon which the photosensitive medium resides; and applying a new layer of the photosensitive medium. |
| FILED | Monday, January 30, 2017 |
| APPL NO | 15/419600 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Foundry Moulding B22C 9/02 (20130101) B22C 9/10 (20130101) B22C 9/24 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0805 (20130101) B29C 64/40 (20170801) B29C 64/129 (20170801) B29C 64/135 (20170801) B29C 64/386 (20170801) B29C 2035/0827 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) Original (OR) Class Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/70291 (20130101) G03F 7/70416 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/292 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336444 | Darrow, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | David A. Darrow, Jr. (Stratford, Connecticut); Frederick J. Miner (Barkhamsted, Connecticut) |
| ABSTRACT | A rotor includes a blade retention cuff configured to receive a rotor blade; a yoke coupled to the blade retention cuff; and a rigid propeller shaped hub configured to enclose at least a portion of the blade retention cuff and at least a portion of the yoke. |
| FILED | Friday, June 13, 2014 |
| APPL NO | 14/915084 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/10 (20130101) B64C 27/32 (20130101) Original (OR) Class B64C 2027/8236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336446 | Orbon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | James Orbon (New Haven, Connecticut); Joseph John Andrews (Hamden, Connecticut); Devon Cowles (New Milford, Connecticut); Stephen V. Poulin (Milford, Connecticut) |
| ABSTRACT | A bearing sleeve assembly includes a rigid inner element having a cylindrical inner diameter bore and an outer surface that is non-cylindrical. Also included is a rigid outer element spaced radially outwardly from the rigid inner element, the rigid outer element comprising a cylindrical member with a uniform cross-section that forms a ring with an inner-diameter surface and an outer-diameter surface, the outer element's inner-diameter surface and the non-cylindrical outer surface of the inner element defining a non-uniform annulus therebetween. Further included is an elastomeric core disposed between the rigid inner element and the rigid outer element within the non-uniform annulus, the elastomeric core having a first thickness at a first location and a second thickness at a second location, the first thickness being greater than the second thickness. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/343659 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/10 (20130101) B64C 27/35 (20130101) Original (OR) Class B64C 2027/8236 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 19/26 (20130101) F16C 21/00 (20130101) F16C 27/063 (20130101) F16C 27/066 (20130101) F16C 33/62 (20130101) F16C 33/583 (20130101) F16C 2326/43 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336662 | Mannion et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Department of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph D Mannion (Washington, District of Columbia); John P Consaga (Diamond Point, New York) |
| ABSTRACT | The invention is an article of manufacture, a composition of matter and an in-situ process for making non-hygroscopic ammonium nitrate prills. The non-hygroscopic prills are formed from dried prills of ammonium nitrate, in reaction vessel having an inert gas atmosphere and a nonpolar reaction diluent. A shell is formed in situ by reacting a first reactant with a second reactant in the presence of the AN prills en masse. The prills, en masse, are individually sealed in the shell made of a highly crosslinked polymeric material. The material is a reaction product of a diglycidyl hydantoin and a polyoxypropylene-triamine. |
| FILED | Monday, September 26, 2016 |
| APPL NO | 15/330472 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 31/30 (20130101) C06B 45/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336705 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Brett D. Martin (Washington, District of Columbia); Scott A. Trammell (Springfield, Virginia); Jeffrey R. Deschamps (Laurel, Maryland); Jawad Naciri (Arlington, Virginia); Jeffrey DePriest (Stanley, Virginia) |
| ABSTRACT | An electrically conducting organic oligomer comprising 4-nitro-1H-pyrazole-3-yl-amine, 4-trifluoromethyl-1H-pyrazol-3-yl-amine, 4-trichloromethyl-1H-pyrazol-3-yl-amine, 4-tribromomethyl-1H-pyrazol-3-yl-amine, 4-ammonium-1H-pyrazol-3-yl-amine, 4-trimethylammonium-1H-pyrazol-3-yl-amine, 4-triethylammonium-1H-pyrazol-3-yl-amine, or 4-tripropylammonium-1H-pyrazol-3-yl-amine. An electrically conducting organic oligomer made from the steps of preparing an acidic aqueous solution with a monomer, preparing the acidic aqueous solution by mixing water with a monomer (3-amino-1H-pyrazole-4-carbonitrile), forming a solution preparing a second aqueous solution, mixing the acidic aqueous solution with the second aqueous solution, and allowing a reaction to proceed at about 40° C. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 15/610324 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 231/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336745 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretery of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Loon-Seng Tan (Centerville, Ohio); Zhenning Yu (Beavercreek, Ohio) |
| ABSTRACT | A two-photon absorbing (TPA) compound is provided along with a method of making same. The TPA compound has a general structural formula: where R1 and R2 are independently selected from the group consisting of linear or branched alkyl chains having a general formula CnH2n+1, n ranges from about 6 to about 20, and ethoxylated alkyls having a general formula R3(OCH2CH2)mOCH2CH2—, where R3 is a C1 to C4 alkyl group, and where m ranges from 0 to about 3; and where Y is selected from the group consisting of H, OH, and alkoxyl groups. |
| FILED | Friday, March 02, 2018 |
| APPL NO | 15/910341 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 277/66 (20130101) C07D 417/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337354 | Drake |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Christopher Drake (West Hartford, Connecticut) |
| ABSTRACT | A gas turbine engine includes a vane and a combustor housing that are supported relative to an engine static structure. A retaining assembly clamps the combustor housing and the vane to one another in an axial direction. A circumferential load transfer assembly circumferentially affixes the vane relative to the engine static structure. The retaining assembly is secured to the circumferential load transfer assembly. |
| FILED | Wednesday, September 03, 2014 |
| APPL NO | 14/915755 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/023 (20130101) F01D 9/041 (20130101) F01D 11/003 (20130101) F01D 25/28 (20130101) Original (OR) Class F01D 25/243 (20130101) F01D 25/246 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/35 (20130101) F05D 2260/30 (20130101) F05D 2260/36 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337600 | Ture |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Cody M. Ture (Fairport, New York) |
| ABSTRACT | Disclosed is an apparatus for in-situ filtering and monitoring of a lubricating fluid which includes, among other elements, a housing, a filter assembly and a lubrication monitoring module. The housing is adapted for being secured directly to a source of lubricating fluid and defines an internal filter chamber. The filter assembly is positioned at least partially within the internal filter chamber of the housing and the lubrication monitoring module is in fluid communication with the internal filter chamber of the housing. The filter assembly and the lubrication monitoring module are arranged so as to create first and second flow paths for lubricating fluid within the housing. The first flow path directs a portion of the lubricating fluid from the source, through the filter assembly where it is conditioned and returned to the source. The second flow path directs a second portion of the lubricating fluid from the source to the lubrication monitoring module and subsequently it is returned to the source. |
| FILED | Friday, June 24, 2016 |
| APPL NO | 15/191654 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Gearing F16H 57/0404 (20130101) F16H 57/0405 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337601 | Olson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bell Helicopter Textron Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | Bell Helicopter Textron Inc. (Fort Worth, Texas) |
| INVENTOR(S) | Eric Stephen Olson (Fort Worth, Texas) |
| ABSTRACT | A gear includes a toothed portion that has a plurality of teeth, an inner wall that defines a cavity, and a lubricant feed aperture. The lubricant feed aperture extends from the inner wall portion to a surface of a tooth. The lubricant feed aperture can deliver lubricant from the cavity to the surface of the tooth. |
| FILED | Wednesday, September 30, 2015 |
| APPL NO | 14/870170 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/12 (20130101) Gearing F16H 55/17 (20130101) F16H 57/043 (20130101) F16H 57/0423 (20130101) F16H 57/0426 (20130101) F16H 57/0431 (20130101) Original (OR) Class F16H 57/0442 (20130101) F16H 57/0479 (20130101) F16H 57/0486 (20130101) F16H 57/0495 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337621 | D'Ambruoso et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Tara L. D'Ambruoso (Oxford, Connecticut); Dwayne K. Mecklenburg (Stafford Springs, Connecticut) |
| ABSTRACT | A non-contact seal assembly is provided. The non-contact seal assembly includes a plurality of seal shoes arranged about a centerline in an annular array, the seal shoes include a first seal shoe extending axially along the centerline between a first shoe end and a second shoe end. The non-contact seal assembly may comprise a seal base circumscribing the annular array of the seal shoes. The non-contact seal assembly may further comprise a plurality of spring elements, each of the spring elements radially between and connecting a respective one of the seal shoes with the seal base, where the plurality of seal shoes each includes a weight reduction pocket formed in a circumferential region of the seal shoe. |
| FILED | Friday, June 23, 2017 |
| APPL NO | 15/631527 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/001 (20130101) F01D 11/025 (20130101) F01D 25/22 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/10 (20130101) F05D 2240/20 (20130101) F05D 2240/53 (20130101) Pistons; Cylinders; Sealings F16J 15/441 (20130101) Original (OR) Class F16J 15/442 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337802 | Fedorov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Andrei G. Fedorov (Atlanta, Georgia) |
| ABSTRACT | Capillary trap-vapor pumps, systems, methods of heat management, and the like, are disclosed. |
| FILED | Wednesday, October 01, 2014 |
| APPL NO | 15/516125 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/04 (20130101) Original (OR) Class F28D 15/046 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/187 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/427 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337809 | Shipley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AAI Corporation (Hunt Valley, Maryland) |
| ASSIGNEE(S) | AAI Corporation (Hunt Valley, Maryland) |
| INVENTOR(S) | Paul Andrew Shipley (Millers, Maryland); Joshua Stephen Ruck (Baltimore, Maryland); Benjamin Tyler Cole (Baltimore, Maryland); Brandon Scott Recchia (Parkton, Maryland); Cameron Mehdi Brand (Bel Air, Maryland); Gregory Paul Habiak (Bryn Mawr, Pennsylvania) |
| ABSTRACT | A magazine for storing cased telescoped (CT) cartridges. The magazine includes vertically extending side-wall ribs that project inwards into a loading channel. The side-wall ribs are positioned in alignment with a circumferential groove in each CT cartridge. The side-wall ribs prevent a backwards oriented CT cartridge from being pushed from the loading position through the loading channel into a body of the magazine. A moveable lip at the top of the magazine may move out of the way when the magazine is attached to a firearm, to allow the CT cartridge located in the loading position to be fed vertically out of the top of magazine. Each CT cartridge may include a thermal protective insert that provides thermal insulation from heat emanating from a barrel of a firearm when the CT cartridge is located in a chamber of the firearm. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/044244 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 3/10 (20130101) F41A 3/34 (20130101) Original (OR) Class F41A 5/18 (20130101) F41A 9/66 (20130101) F41A 9/67 (20130101) F41A 9/69 (20130101) F41A 9/75 (20130101) F41A 15/14 (20130101) F41A 21/12 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337814 | Shaker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Department of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Nicholas Shaker (Springfield, Virginia); Michael Craft (Waldorf, Maryland) |
| ABSTRACT | A dearmer positioning system has two assemblies, each of which circumscribes a dearmer's barrel. Each of the two assemblies includes two half rings and a one-piece outer ring. The two half rings are joined to one another to define a full ring having a first central opening defining a first diameter. The full ring has a periphery defining a second diameter. The one-piece outer ring has a second central opening defining a third diameter, and a periphery defining a fourth diameter. The third diameter is greater than the second diameter such that the full ring slidingly fits in the central opening of the outer ring. Threaded fasteners engage the outer ring and extend radially through the outer ring and into its central opening to engage the periphery of the full ring. |
| FILED | Monday, August 15, 2016 |
| APPL NO | 15/330139 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 15/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337821 | Garner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Russell S Garner (Huntland, Tennessee); Dan F Lighton (Huntsville, Alabama); John T Dillon (Huntsville, Alabama) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Russell S Garner (Huntland, Tennessee); Dan F Lighton (Huntsville, Alabama); John T Dillon (Huntsville, Alabama) |
| ABSTRACT | A stable mount is secured firmly to the bed of a vehicle and is of sufficient height to reach an opening in the roof level. The stable mount has five primary parts made of a suitable material and constructed together with welds. The mount has sufficient rigidity such that the first resonant mode of vibration of the mount is greater than the post-actuation resonance of the mounted weapon so that optimal gun bolt actuation is realized and the jamming of rounds is prevented. |
| FILED | Friday, November 21, 2008 |
| APPL NO | 12/313788 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 23/12 (20130101) Original (OR) Class F41A 27/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337838 | McIntosh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Scotlund McIntosh (Framingham, Massachusetts); Lisa Bareiss Hepfinger (Holliston, Massachusetts); Cheryl Ann Stewardson (Hopedale, Massachusetts); Anabela Dugas (Rochester, Massachusetts); James George Fairneny (Roslindale, Massachusetts) |
| ABSTRACT | A garment assembly such as a uniform, a military uniform and a military combat uniform is presented. The garment assembly includes a helmet or head cover being cut from a fabric having a first camouflage pattern with a first set of intermixed colored blotches thereon. The colors of the first set of intermixed colored blotches being selected from a first group of colors including an Olive 527 color, a Dark Green 528 color, a Tan 525 color, a Brown 529 color, a Bark Brown 561 color and a Dark Cream 559 color. The uniform also includes a coat being configured to fit at least a portion of a human torso and a trouser configured to fit at least a portion of human legs, the coat and trouser each being cut from a fabric having a second camouflage pattern with a second set of intermixed colored blotches thereon, the colors of the second set of intermixed colored blotches being selected from a second group of colors comprising an Olive 527 color, a Dark Green 528 color, a Light Sage 560 color, a Tan 525 color, a Brown 529 color, a Bark Brown 561 color and a Dark Cream 559 color. |
| FILED | Tuesday, June 20, 2017 |
| APPL NO | 15/627486 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 29/00 (20130101) A41D 31/00 (20130101) Hats; Head Coverings A42B 3/003 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 3/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
10337993 — Methods and apparatus for fluorescence lifetime imaging with periodically modulated light
| US 10337993 | Bhandari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ayush Bhandari (Cambridge, Massachusetts); Christopher Barsi (Lee, New Hampshire); Achuta Kadambi (Cambridge, Massachusetts); Ramesh Raskar (Cambridge, Massachusetts) |
| ABSTRACT | A light source may illuminate a scene with amplitude-modulated light. The scene may include fluorescent material. The amplitude modulation may be periodic, and the frequency of the amplitude modulation may be swept. During the sweep, a time-of-flight sensor may take measurements of light returning from the scene. A computer may calculate, for each pixel in the sensor, a vector of complex numbers. Each complex number in the vector may encode phase and amplitude of light incident at the pixel and may correspond to measurements taken at a given frequency in the sweep. A computer may, based on phase of the complex numbers for a pixel, calculate fluorescence lifetime and scene depth of a scene point that corresponds to the pixel. |
| FILED | Friday, April 14, 2017 |
| APPL NO | 15/487435 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6408 (20130101) Original (OR) Class G01N 21/6456 (20130101) G01N 2201/126 (20130101) G01N 2201/129 (20130101) G01N 2201/0691 (20130101) Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing G07D 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338000 | Gumennik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); FLIR Systems, Incorporated (Wilsonville, Oregon) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); FLIR Systems, Incorporated (Wilsonville, Oregon) |
| INVENTOR(S) | Alexander Gumennik (Brookline, Massachusetts); Alexander Mark Stolyarov (Belmont, Massachusetts); Brent Richard Schell (Stoughton, Massachusetts); Chong Hou (Cambridge, Massachusetts); Guillaume Romain Lestoquoy (Cambridge, Massachusetts); Fabien Sorin (Saintj-Sulpice, France); William Richard McDaniel, II (Worcester, Massachusetts); Yoel Fink (Brookline, Massachusetts); Aimee Rose (Cambridge, Massachusetts); John Dimitris Joannopoulos (Belmont, Massachusetts) |
| ABSTRACT | There is provided a sensor fiber including an electrically insulating material having a fiber length. At least one transduction element is disposed along at least a portion of the fiber length and is arranged for exposure to an intake species. A photoconducting element is in optical communication with the transduction element. At least one pair of electrically conducting electrodes are in electrical connection with the photoconducting element. The pair of electrodes extend the fiber length. |
| FILED | Tuesday, September 24, 2013 |
| APPL NO | 14/035933 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00721 (20130101) Manufacture, Shaping, or Supplementary Processes C03B 2201/86 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/76 (20130101) G01N 21/84 (20130101) Original (OR) Class G01N 21/7703 (20130101) G01N 2021/7753 (20130101) G01N 2021/7786 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02314 (20130101) G02B 6/4283 (20130101) G02B 6/4291 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338052 | Chekmenev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Eduard Y. Chekmenev (Brentwood, Tennessee); Roman V. Shchepin (Nashville, Tennessee) |
| ABSTRACT | Methods of detecting a sulfur-containing compound in a sample are described, for example using NMR-SABRE hyperpolarization of the sulfur-containing compounds in the sample. The methods can comprise, for example, contacting a sample comprising a sulfur-containing compound with parahydrogen and a catalyst to form a mixture. A spin order can be transferred from the parahydrogen to the sulfur-containing compound thereby hyperpolarizing the sulfur-containing compound during a temporary association of the parahydrogen, the sulfur-containing compound, and the catalyst. The methods can further comprise, for example, performing an NMR measurement on the mixture comprising the hyperpolarized sulfur-containing compound to detect the hyperpolarized sulfur-containing compound (e.g., from the hyperpolarized NMR signals. In some examples, the methods described herein can be used for detecting a sulfur-containing contaminant in a fuel. |
| FILED | Tuesday, November 29, 2016 |
| APPL NO | 15/362846 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/08 (20130101) G01N 33/287 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/282 (20130101) G01R 33/307 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338070 | Ervin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ELECTRONIC BIO SCIENCES, INC. (San Diego, California) |
| ASSIGNEE(S) | Electronic BioSciences, Inc. (San Diego, California) |
| INVENTOR(S) | Eric Ervin (Salt Lake City, Utah); Anna E. P. Schibel (Snoqualmie, Washington) |
| ABSTRACT | Provided herein is a cell-free assay device, sometimes comprising a lipid bilayer and an endopeptidase assay component, for characterizing a pore forming protein. In some embodiments provided herein is an apparatus comprising a pressure system for characterizing an interaction. Also, provided herein are methods for using a cell-free assay device to characterize a pore forming protein and/or a test substance. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 15/498864 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/573 (20130101) Original (OR) Class G01N 33/6872 (20130101) G01N 33/48721 (20130101) G01N 2333/952 (20130101) G01N 2500/20 (20130101) G01N 2800/709 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338156 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Dong Ho Wu (Olney, Maryland); Anthony Garzarella (Ellicott City, Maryland) |
| ABSTRACT | An ultra-sensitivity optical-fiber magneto-optic field sensor includes an input fiber passing optical power from an optical source into the sensor; a polarizer optically coupled to and downstream of the input fiber; an analyzer optically coupled to and downstream of the polarizer; an output fiber passing optical power out of the sensor to a photoreceiver; and a magneto-optic crystal element optically coupled between the polarizer and the analyzer. The ultra-sensitivity optical-fiber magneto-optic field sensor has an optical axis extending between the input and output fibers along which a beam of optical power is transmitted. |
| FILED | Wednesday, June 01, 2016 |
| APPL NO | 15/170569 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/032 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338157 | de Andrade et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Marcio C. de Andrade (San Diego, California); Anna Leese de Escobar (San Diego, California); Brandon J. Wiedemeier (San Diego, California); Jamie R. Lukos (San Diego, California); Shannon Kasa (San Diego, California); Matthew A. Yanagi (Jamul, California) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Marcio C. de Andrade (San Diego, California); Anna Leese de Escobar (San Diego, California); Brandon J. Wiedemeier (San Diego, California); Jamie R. Lukos (San Diego, California); Shannon Kasa (San Diego, California); Matthew A. Yanagi (Jamul, California) |
| ABSTRACT | A biosignal measuring device that can include at least one Super-conducting Quantum Interference Device (SQUID) array (SQA) of High Temperature Superconducting (HTS) Josephson Junctions (JJs). The HTS JJs operating parameters can be adjusted to establish an anti-peak response for the SQA, that can be at a maximum along a defined response axis, for detection of extremely small biomagnetic fields. For operation, the SQA can be maneuvered around a target area of a stationary subject that is emitting biomagnetic signals using a stand with three degrees of freedom, so that the response axis remains orthogonal to the subject target area. The device can further include a radome with an atomic layer deposition (ALD) window on the radome surface. The radome ALD surface can allow for passage of magnetic signals through the ALD window and radome, while simultaneously preventing passage of infrared radiation therethrough. |
| FILED | Wednesday, May 16, 2018 |
| APPL NO | 15/980969 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/04008 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/035 (20130101) G01R 33/0354 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 1/364 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338207 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intelligent Fusion Technology, Inc (Germantown, Maryland) |
| ASSIGNEE(S) | Intelligent Fusion Technology, Inc. (Germantown, Maryland) |
| INVENTOR(S) | Zhonghai Wang (Germantown, Maryland); XingPing Lin (Germantown, Maryland); Genshe Chen (Germantown, Maryland); Dan Shen (Germantown, Maryland); Bin Jia (Germantown, Maryland); Gang Wang (Germantown, Maryland); Khanh Pham (Germantown, Maryland); Erik Blasch (Rome, New York) |
| ABSTRACT | The present disclosure provides a gated range scanning linear frequency modulated continuous wave (LFMCW) radar structure, including: a frequency synthesizer, a first mixer, a second mixer, a first filter, and a third mixer. The frequency synthesizer is configured for generating a first local oscillating signal and a second local oscillating signal, a frequency of the first local oscillating signal varying in a frequency range, each frequency corresponding to a sub-range of a coverage range scanned by the LFMCW radar structure. The first mixer is configured for mixing a copy of a transmitted signal and the first local oscillating signal to generate a first output signal (the receiver's first local oscillator). The second mixer is configured for mixing the first output signal and a received signal from a receiving antenna to generate a second output signal that includes an intermediate frequency (IF) signal being received by the first filter. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/344365 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/354 (20130101) G01S 13/18 (20130101) G01S 13/34 (20130101) Original (OR) Class G01S 13/343 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338315 | Thapa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Rajesh Thapa (Manassas, Virginia); Rafael R. Gattass (Washington, District of Columbia); Daniel J. Gibson (Falls Church, Virginia); Woohong Kim (Washington, District of Columbia); L. Brandon Shaw (Woodbridge, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
| ABSTRACT | Systems and methods are disclosed for splicing crystal fibers to silica glass fibers. Embodiments of the present disclosure provide mechanically stable bonds with negligible optical transmission loss by splicing fibers through a thermally enhanced reaction bonding process at lower temperatures than the melting point of the crystal. In an embodiment, mixing of the materials at elevated temperatures forms a stable intermediary material which enhances strength and reduces the transmission losses. |
| FILED | Monday, October 16, 2017 |
| APPL NO | 15/784698 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/02 (20130101) G02B 6/2551 (20130101) Original (OR) Class G02B 6/2553 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338319 | Miller |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | David A. B. Miller (Stanford, California) |
| ABSTRACT | A modified directional coupler structure is used to provide a controllable time delay or phase shift for radiation propagating through the structure. A longitudinal displacement of the interaction region of the directional coupler relative to one or both of the waveguides of the directional coupler provides this effect. Double flexure arrangements can be used to provide longitudinal displacement with substantially no corresponding lateral displacement (or vice versa). In some embodiments, lateral and longitudinal displacement of the waveguides of the directional coupler are independently adjustable to provide full control of the power splitting and phase shift/time delay of the directional coupler. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 15/380062 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/29331 (20130101) G02B 6/29395 (20130101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/182 (20130101) H01P 3/16 (20130101) H01P 5/04 (20130101) H01P 5/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338790 | Keel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paul Erich Keel (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Paul Erich Keel (Cambridge, Massachusetts) |
| INVENTOR(S) | Paul Erich Keel (Cambridge, Massachusetts); Jeffrey Huang (Lausanne, Switzerland) |
| ABSTRACT | A computer-implemented method of interacting with at least one data item includes storing, in a database system, a configuration, of each of the data items as a distinct information object, in which each information object has an association with a picture and a heading and/or a link to the corresponding data item. The method additionally uses the stored configurations to make available for display a representation of each of at least two of the information objects in a uniform format, wherein the format includes a card, and, within the card, at least the picture, a set of indicators, the set of indicators having at least one member, and a set of graphically accessible functions. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/148379 |
| ART UNIT | 2173 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/04817 (20130101) G06F 3/04842 (20130101) Original (OR) Class G06F 16/22 (20190101) G06F 16/29 (20190101) G06F 16/258 (20190101) G06F 16/9535 (20190101) G06F 16/9537 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 51/046 (20130101) H04L 67/10 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 707/99933 (20130101) Y10S 707/99943 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338931 | Gupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Suyog Gupta (White Plains, New York); Ravi Nair (Briarcliff Manor, New York) |
| ABSTRACT | Techniques facilitating synchronization of processing engines for parallel deep learning are provided. In one example, a first processing component associated with a processor and processing components can: generate first output data based on input data associated with a machine learning process, wherein the processing components are communicatively coupled with an assignment component via a network; transmit the first output data to a second processing component of the processing components, wherein the first processing component and the second processing component comprise a first group of the processing components and the first group of the processing components is determined by the assignment component based on a first defined criterion; receive communication data generated by the second processing component; and generate second output data based on the communication data, wherein the second output data is an updated version of the first output data stored in the memory of the first processing component. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/142553 |
| ART UNIT | 2195 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3885 (20130101) G06F 9/4405 (20130101) Original (OR) Class G06F 9/30087 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Wireless Communication Networks H04W 56/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338970 | Kirchner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Peter D. Kirchner (Putnam Valley, New York); Krzysztof P. Onak (Scarsdale, New York); Robert Saccone (Glen Head, New York); Kanthi Sarpatwar (Mohegan Lake, New York); Joel L. Wolf (Goldens Bridge, New York) |
| ABSTRACT | A method of scheduling assignment of resources to a plurality of applications includes: determining shares of the resources assigned to each application during a first period; determining shares of the resources assigned to each application during a second period that occurs after the first period; determining an imbalance value for each application that is based on a sum of the shares assigned to the corresponding application over both periods; and considering requests of the applications for resources in an order that depends on a result of comparing the imbalance values of the applications. |
| FILED | Tuesday, September 20, 2016 |
| APPL NO | 15/270975 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) Original (OR) Class G06F 9/4881 (20130101) G06F 9/5005 (20130101) G06F 9/5083 (20130101) G06F 9/5088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339015 | Bose et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Pradip Bose (Yorktown Heights, New York); Alper Buyuktosunoglu (White Plains, New York); Jingwen Leng (Yorktown Heights, New York); Ramon Bertran Monfort (Bronx, New York) |
| ABSTRACT | A computer-implemented method is provided that is performed in a computer having a processor and multiple co-processors. The method includes launching a same set of operations in each of an original co-processor and a redundant co-processor, from among the multiple co-processors, to obtain respective execution signatures from the original co-processor and the redundant co-processor. The method further includes detecting an error in an execution of the set of operations by the original co-processor, by comparing the respective execution signatures. The method also includes designating the execution of the set of operations by the original co-processor as error-free and committing a result of the execution, responsive to identifying a match between the respective execution signatures. The method additionally includes performing an error recovery operation that replays the set of operations by the original co-processor and the redundant co-processor, responsive to identifying a mismatch between the respective execution signatures. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 15/832251 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1629 (20130101) G06F 11/1658 (20130101) Original (OR) Class G06F 2201/82 (20130101) G06F 2201/805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339266 | Urick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | Board of Regents of the University of Texas Systems (Austin, Texas); University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Benjamin Urick (Austin, Texas); Thomas J. R. Hughes (Austin, Texas); Richard H. Crawford (Austin, Texas); Elaine Cohen (Salt Lake City, Utah); Richard F. Riesenfeld (Salt Lake City, Utah) |
| ABSTRACT | A mechanism is disclosed for reconstructing trimmed surfaces whose underlying spline surfaces intersect in model space, so that the reconstructed version of each original trimmed surface is geometrically close to the original trimmed surface, and so that the boundary of each respective reconstructed version includes a model space trim curve that approximates the geometric intersection of the underlying spline surfaces. Thus, the reconstructed versions will meet in a continuous fashion along the model space curve. The mechanism may operate on already trimmed surfaces such as may be available in a boundary representation object model, or, on spline surfaces that are to be trimmed, e.g., as part of a Boolean operation in a computer-aided design system. The ability to create objects with surface-surface intersections that are free of gaps liberates a whole host of downstream industries to perform their respective applications without the burdensome labor of gap repair, and thus, multiplies the efficacy of those industries. |
| FILED | Wednesday, February 15, 2017 |
| APPL NO | 15/433823 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 17/50 (20130101) G06F 17/175 (20130101) G06F 17/5009 (20130101) G06F 17/5018 (20130101) G06F 17/5095 (20130101) Original (OR) Class G06F 2217/02 (20130101) G06F 2217/16 (20130101) Image Data Processing or Generation, in General G06T 17/30 (20130101) G06T 19/20 (20130101) G06T 2219/2021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339387 | Beard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brigham Young University (Provo, Utah) |
| ASSIGNEE(S) | Brigham Young University (Provo, Utah) |
| INVENTOR(S) | Randal W. Beard (Orem, Utah); Peter C. Niedfeldt (Provo, Utah); James K. Ingersoll (Snohomish, Washington); Patrick Defranco (Missouri City, Texas) |
| ABSTRACT | For automated detection and tracking of multiple targets, an apparatus, method, and program product are disclosed. The apparatus includes a camera that captures video data and a processor that compensates for camera motion in the video data, processes the compensated video data to remove noise and spurious returns, detects one or more targets within the processed video data, and identifies target information for each target in the processed video data. |
| FILED | Friday, March 03, 2017 |
| APPL NO | 15/449812 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/127 (20130101) B64C 2201/141 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/40 (20130101) G06K 9/46 (20130101) G06K 9/00651 (20130101) G06K 9/00771 (20130101) Original (OR) Class G06K 9/6202 (20130101) G06K 9/6211 (20130101) G06K 2009/3291 (20130101) G06K 2209/21 (20130101) Image Data Processing or Generation, in General G06T 7/254 (20170101) G06T 7/277 (20170101) G06T 7/292 (20170101) G06T 2207/10016 (20130101) G06T 2207/10032 (20130101) G06T 2207/30212 (20130101) G06T 2207/30232 (20130101) Pictorial Communication, e.g Television H04N 5/23258 (20130101) H04N 5/23267 (20130101) H04N 7/181 (20130101) H04N 7/183 (20130101) H04N 7/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339681 | Moore |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Erik M. Moore (McKinney, Texas) |
| ABSTRACT | According to an aspect a method for building an interactive multimedia process flow chart is provided. The method includes displaying a process flow chart in an interactive graphically editable format on a user interface. The process flow chart includes a plurality of nodes each located entirely in a single node cell of a node grid. A pair of output hubs on a decision node of the process flow chart is linked to a pair of nodes defining a yes-path and a no-path. An output hub of a process step node of the process flow chart is linked to a single node defining a next process step. A link is established to an end node of the process flow chart absent any output links from the end node. The decision node, process step node, and end node each have a common shape including a display region and an editing command region. |
| FILED | Friday, November 22, 2013 |
| APPL NO | 14/087356 |
| ART UNIT | 2178 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04817 (20130101) G06F 8/34 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/00 (20130101) Image Data Processing or Generation, in General G06T 11/206 (20130101) Original (OR) Class G06T 2200/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339685 | Fu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Yun Fu (Wellesley, Massachusetts); Shuyang Wang (Malden, Massachusetts) |
| ABSTRACT | A system and method are provided to detect, analyze and digitally remove makeup from an image of a face. An autoencoder-based framework is provided to extract attractiveness-aware features to perform an assessment of facial beauty. |
| FILED | Monday, February 23, 2015 |
| APPL NO | 15/120287 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/00268 (20130101) G06K 9/00671 (20130101) Image Data Processing or Generation, in General G06T 3/0093 (20130101) G06T 11/00 (20130101) G06T 11/60 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339706 | Black et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Michael J. Black (Providence, Rhode Island); Alexandru O. Balan (Pawtucket, Rhode Island); Alexander W. Weiss (Shirley, Massachusetts); Leonid Sigal (Pittsburgh, Pennsylvania); Matthew M. Loper (Providence, Rhode Island); Timothy S. St. Clair (Cambridge, Massachusetts) |
| ABSTRACT | A system and method of estimating the body shape of an individual from input data such as images or range maps. The body may appear in one or more poses captured at different times and a consistent body shape is computed for all poses. The body may appear in minimal tight-fitting clothing or in normal clothing wherein the described method produces an estimate of the body shape under the clothing. Clothed or bare regions of the body are detected via image classification and the fitting method is adapted to treat each region differently. Body shapes are represented parametrically and are matched to other bodies based on shape similarity and other features. Standard measurements are extracted using parametric or non-parametric functions of body shape. The system components support many applications in body scanning, advertising, social networking, collaborative filtering and Internet clothing shopping. |
| FILED | Thursday, June 14, 2018 |
| APPL NO | 16/008637 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00369 (20130101) G06K 9/6221 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0601 (20130101) Image Data Processing or Generation, in General G06T 7/75 (20170101) G06T 7/77 (20170101) G06T 17/00 (20130101) Original (OR) Class G06T 2207/10028 (20130101) G06T 2207/30196 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339730 | Rivera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGY CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Linda I. Rivera (Norwalk, Connecticut); Gregory S. Hagen (Glastonbury, Connecticut); Alexander I. Khibnik (Melrose, Massachusetts) |
| ABSTRACT | An article of manufacture including a tangible, non-transitory computer-readable storage medium having instructions stored thereon for detecting a fault in a gas turbine engine that, in response to execution by a controller, cause the controller to perform operations comprising receiving, by the controller, a first data output from a first flight data source; receiving, by the controller, a second data output from a second flight data source; determining, by the controller, a first flight realm of the first data output based on the second data output; identifying, by the controller, a fault threshold using a first parameter of the first flight realm; and comparing, by the controller, the first data output to the fault threshold. |
| FILED | Tuesday, May 09, 2017 |
| APPL NO | 15/590565 |
| ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 45/00 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/60 (20170101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 23/0235 (20130101) G05B 23/0245 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/0816 (20130101) Original (OR) Class Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/187 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340187 | Forrest et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents Of The University Of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Kyusang Lee (Ann Arbor, Michigan); Dejiu Fan (Ann Arbor, Michigan) |
| ABSTRACT | Disclosed herein are methods to eliminate or reduce the peeling-off of epitaxial lifted-off thin film epilayers on secondary host substrates that allow for the fabrication of high yield ELO processed thin film devices. The methods employ patterned strain-relief trenches. |
| FILED | Friday, March 18, 2016 |
| APPL NO | 15/558230 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 13/00 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 33/08 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/78 (20130101) Original (OR) Class H01L 21/7813 (20130101) H01L 31/1896 (20130101) H01L 33/0079 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340353 | Meyer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David J. Meyer (Fairfax, Virginia); Brian P. Downey (Alexandria, Virginia); Douglas S. Katzer (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David J. Meyer (Fairfax, Virginia); Brian P. Downey (Alexandria, Virginia); Douglas S. Katzer (Alexandria, Virginia) |
| ABSTRACT | A method for integrating epitaxial, metallic transition metal nitride (TMN) layers within a compound semiconductor device structure. The TMN layers have a similar crystal structure to relevant semiconductors of interest such as silicon carbide (SiC) and the Group III-Nitrides (III-Ns) such as gallium nitride (GaN), aluminum nitride (AlN), indium nitride (InN), and their various alloys. Additionally, the TMN layers have excellent thermal stability and can be deposited in situ with other semiconductor materials, allowing the TMN layers to be buried within the semiconductor device structure to create semiconductor/metal/semiconductor heterostructures and superlattices. |
| FILED | Thursday, July 30, 2015 |
| APPL NO | 14/813460 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/0485 (20130101) H01L 21/0495 (20130101) H01L 21/02378 (20130101) H01L 21/02458 (20130101) H01L 21/02491 (20130101) H01L 21/02505 (20130101) H01L 21/02529 (20130101) H01L 29/45 (20130101) Original (OR) Class H01L 29/452 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340596 | Gardner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Atlantic (San Diego, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Chad Michael Gardner (Charleston, South Carolina); Colin MacFarland Thomas (Charleston, South Carolina) |
| ABSTRACT | A method for resonating a conductive structure as an antenna comprising: connecting a radio frequency (RF) resonator to a transceiver, wherein the RF resonator has a conductive layer; attaching the conductive layer of the resonator to the conductive structure at a given location; balancing the impedance of the transceiver with the impedance of the conductive structure at the given location; and receiving and radiating electromagnetic waves through the conductive structure at an operating frequency of the transceiver, wherein the conductive structure has a dimension of at least one-half wavelength of the operating frequency of the transceiver. |
| FILED | Wednesday, October 24, 2018 |
| APPL NO | 16/169687 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/44 (20130101) H01Q 5/335 (20150115) Original (OR) Class Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340606 | Elsallal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The MITRE Corporation (McLean, Virginia); The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Wajih Elsallal (Acton, Massachusetts); Jamie Hood (Owatonna, Minnesota); Al Locker (Westford, Massachusetts); Rick W. Kindt (Arlington, Virginia) |
| ABSTRACT | An antenna element that includes a base plate, a first ground clustered pillar projecting from the base plate, a second ground clustered pillar projecting from the base plate and spaced apart from a first side of the first ground clustered pillar, a first ground member projecting from the base plate between the first ground clustered pillar and the second ground clustered pillar, wherein a distal end of the first ground member is configured to capacitively couple to the second ground clustered pillar, and a first signal member projecting from the base plate between the first ground clustered pillar and the first ground member, wherein the first signal member is electrically insulated from the base plate, the first ground clustered pillar, and the first ground member, and a distal end of the first signal member is configured to capacitively couple to the first ground clustered pillar. |
| FILED | Tuesday, May 22, 2018 |
| APPL NO | 15/986413 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/30 (20130101) H01Q 13/085 (20130101) H01Q 21/24 (20130101) H01Q 21/062 (20130101) H01Q 21/064 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340658 | Boyd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AOSense, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | AOSense, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Martin M. Boyd (Sunnyvale, California); Brian R. Patton (San Francisco, California) |
| ABSTRACT | A laser system for atomic clocks and sensors includes a single laser, an intensity splitter, a modulator, and a feedback-based lock controller. The single laser outputs a central optical frequency of laser light that can be tuned. The intensity splitter splits the laser light along a first and a second optical path. A modulator is disposed in the first optical path. The portion of laser light from the first optical path is subjected to the modulator with the modulator disposed to generate a frequency-shifted sideband from some or all of the portion of the laser light subjected to the modulator, with the frequency-shifted sideband shifted by an adjustable frequency source, resulting in an adjustable frequency offset between the frequency-shifted sideband and an unmodulated carrier propagating in the second optical path. The feedback-based lock controller locks the optical frequency of the frequency-shifted sideband to a repumping transition for atom cooling. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/967405 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/10 (20130101) H01S 3/13 (20130101) H01S 3/0085 (20130101) H01S 3/105 (20130101) H01S 3/1305 (20130101) H01S 3/08086 (20130101) H01S 3/10092 (20130101) H01S 5/12 (20130101) H01S 5/14 (20130101) H01S 5/0085 (20130101) H01S 5/125 (20130101) H01S 5/142 (20130101) H01S 5/146 (20130101) H01S 5/0687 (20130101) Original (OR) Class H01S 5/02284 (20130101) H01S 5/4012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340812 | Jacobson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Boris S. Jacobson (Westford, Massachusetts); Steven D. Bernstein (Brighton, Massachusetts); Steven M. Lardizabal (Westford, Massachusetts); Jason Adams (Medway, Massachusetts); Jeffrey R. Laroche (Austin, Texas) |
| ABSTRACT | A modular high-power converter system includes an electronic power distribution unit configured to output an analog current (AC) voltage to a power bus, and at least one Transmit or Receive Integrated Microwave Module (T/RIMM) that includes a voltage converter unit and a transmitter and receiver (T/R) unit. The voltage converter unit includes at least one analog-to-digital converter (ADC) to convert the AC voltage into a direct current (DC) voltage having a first DC voltage level. The transmitter and receiver (T/R) unit includes a modular-based DC/DC converter to convert the DC voltage into a second DC voltage having a second voltage. The modular-based DC/DC converter includes a modular power converter unit configured to generate the second DC voltage. The modular converter unit is configured to be independently interchangeable with a different modular converter unit. |
| FILED | Wednesday, September 13, 2017 |
| APPL NO | 15/703455 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/28 (20130101) H01F 27/42 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/335 (20130101) H02M 7/003 (20130101) Original (OR) Class H02M 7/04 (20130101) H02M 2001/007 (20130101) H02M 2001/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340962 | Utter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Alexander C. Utter (Hawthorne, California); Philip Dafesh (Manhattan Beach, California); Phillip Brian Hess (Venice, California) |
| ABSTRACT | Under one aspect, a method for reducing interference in a received signal can include splitting a received signal into a first portion and a second portion, the received signal comprising a desired signal and an interference signal that spectrally overlaps the desired signal. The method also can include estimating an amplitude A(t) of the first portion as a function of time. The method also can include suppressing at least a portion of the interference signal in the estimated amplitude A(t) to generate an interference suppressed amplitude A′(t). The method also can include delaying the second portion by an amount of time corresponding to the estimation and suppression. The method also can include multiplying the interference suppressed amplitude A′(t) by the delayed second portion to obtain an output having reduced contribution from the interference signal. |
| FILED | Friday, May 06, 2016 |
| APPL NO | 15/149002 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/1036 (20130101) Original (OR) Class H04B 2001/1063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340965 | Dolgin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Benjamin P. Dolgin (Alexandria, Virginia); Thomas Lavedas (Moneta, Virginia); Joseph J. Fraundorfer (Portsmouth, Rhode Island) |
| ABSTRACT | Examples of passive diode-based transmitter detuning circuits and low-voltage active diode-based and receiver detuning circuits are provided. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 15/964477 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Demodulation or Transference of Modulation From One Carrier to Another H03D 7/1408 (20130101) H03D 2200/0013 (20130101) Transmission H04B 1/14 (20130101) Original (OR) Class H04B 1/1018 (20130101) H04B 1/1027 (20130101) H04B 2001/1072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10341031 | Hutchinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Meredith N. Hutchinson (Washington, District of Columbia); Nicholas Frigo (Silver Spring, Maryland); Caitlin R. S Williams (Hastings, Nebraska) |
| ABSTRACT | A communication system includes an optical receiver that receives a modulated optical signal and converts same back to electrical form by a photodiode. The photodiode includes an optical input and a dc bias input, and outputs a photocurrent. The optical communication system includes a photodiode linear operation point feedback loop communicating with the photodiode based on an intermodulation distortion contour plot corresponding to the photodiode. The intermodulation distortion contour plot includes a plurality of linear operation points for the photodiode. The photodiode linear operation point feedback loop operates the photodiode at a respective operation point of the plurality of linear operation points. Optionally, the photodiode linear operation point feedback loop includes a voltage-biasing feedback loop receiving the photocurrent and outputting to the dc bias input a bias voltage based on the intermodulation distortion contour plot, and/or an optical power regulating feedback loop communicating with the optical input. |
| FILED | Tuesday, April 10, 2018 |
| APPL NO | 15/949138 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/807 (20130101) H04B 10/2507 (20130101) H04B 10/2575 (20130101) H04B 10/6911 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10341108 | Smayling et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Multibeam Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael C. Smayling (Fremont, California); David K. Lam (Saratoga, California); Theodore A. Prescop (San Jose, California); Kevin M. Monahan (Cupertino, California) |
| ABSTRACT | Methods, systems and devices for using charged particle beams (CPBs) to write different die-specific, non-volatile, electronically readable data to different dies on a substrate. CPBs can fully write die-specific data within the chip interconnect structure during the device fabrication process, at high resolution and within a small area, allowing one or multiple usefully-sized values to be securely written to service device functions. CPBs can write die-specific data in areas readable or unreadable through a (or any) communications bus. Die-specific data can be used for, e.g.: encryption keys; communications addresses; manufacturing information (including die identification numbers); random number generator improvements; or single, nested, or compartmentalized security codes. Die-specific data and locations for writing die-specific data can be kept in encrypted form when not being written to the substrate to conditionally or permanently prevent any knowledge of said data and locations. |
| FILED | Thursday, October 13, 2016 |
| APPL NO | 15/293090 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 3/067 (20130101) G06F 3/0623 (20130101) G06F 3/0659 (20130101) G06F 21/602 (20130101) G06F 21/606 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/14 (20130101) H04L 9/30 (20130101) H04L 9/32 (20130101) Original (OR) Class H04L 9/0861 (20130101) H04L 2209/127 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10341302 | Khazan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Roger I. Khazan (Arlington, Massachusetts); Daniil M. Utin (Waban, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Roger I. Khazan (Arlington, Massachusetts); Daniil M. Utin (Waban, Massachusetts) |
| ABSTRACT | A method for establishing a secure communication session over communication paths between one or more client devices and one or more server computers according to a communication protocol includes initiating the session including passing communication through a proxy on a device on the communication paths, passing session initiation information between the client devices and the server computers via the proxy, passing encrypted content between the client devices and the server computers over secure communication sessions, each established for exclusive access from one client device and one server computer based on the exchanged session initiation information between said client device and said server computer whereby the proxy does not have access to the content, and modifying, using the proxy, at least some information passing between a client device and a server computer such that the communication to and from the server computer adheres to the communication protocol. |
| FILED | Friday, May 06, 2016 |
| APPL NO | 15/148327 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/14 (20130101) H04L 9/30 (20130101) H04L 9/3263 (20130101) H04L 63/061 (20130101) H04L 63/166 (20130101) H04L 63/0281 (20130101) H04L 63/0428 (20130101) Original (OR) Class H04L 63/0823 (20130101) H04L 67/2876 (20130101) H04L 69/04 (20130101) H04L 2209/80 (20130101) Wireless Communication Networks H04W 12/02 (20130101) H04W 12/04 (20130101) H04W 12/06 (20130101) H04W 76/12 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10341378 | Cui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Ang Cui (New York, New York); Salvatore J. Stolfo (New York, New York) |
| ABSTRACT | Methods, systems, and media for inhibiting attacks on embedded devices are provided. In some embodiments, a system for inhibiting on embedded devices is provided, the system comprises a processor that is configured to: identify an embedded device that is configured to provide one or more services to one or more digital processing devices within a communications network; receive a first firmware associated with the embedded device; generate a second firmware that is functionally equivalent to the first firmware by: determining unused code within the first firmware; removing the unused code within the second firmware; and restructuring remaining code portions of the first firmware into memory positions within the second firmware; and inject the second firmware into the embedded device. |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/136581 |
| ART UNIT | 2492 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/54 (20130101) G06F 21/64 (20130101) G06F 21/572 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/145 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10341555 | Menon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Naresh Menon (Pasadena, California); Gregory Howard Bearman (Pasadena, California); Leonard Nelson (Pasadena, California) |
| ASSIGNEE(S) | Chromologic LLC (Monrovia, California) |
| INVENTOR(S) | Naresh Menon (Pasadena, California); Gregory Howard Bearman (Pasadena, California); Leonard Nelson (Pasadena, California) |
| ABSTRACT | The present invention is directed to a method and apparatus that involves improved characterization of an object based on its surface roughness and other unique features without having to necessarily define a fixed and predetermined region of interest. In accordance with one aspect, the present invention provides a method for characterizing an object based on a pattern of the object's surface roughness. The method comprises the steps of obtaining a unique image of a feature on the surface of the object, converting the image obtained into certain electrical signals and processing the electrical signals so they are associated with the object and thereby provide a characterization of the object that is used to generate a unique identifying signature for the object. |
| FILED | Wednesday, October 10, 2012 |
| APPL NO | 13/573868 |
| ART UNIT | 2481 — Recording and Compression |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4738 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) H04N 5/23222 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10341606 | Davey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SA Photonics, Inc. (Los Gatos, California) |
| ASSIGNEE(S) | SA Photonics, Inc. (Los Gatos, California) |
| INVENTOR(S) | James Arundell Davey (Sunnyvale, California) |
| ABSTRACT | Systems and methods of multiplexing information from a plurality of monochrome sensors/cameras is provided. The systems and methods provided can be useful to achieve pixel-level time synchronization between information acquired by different monochrome sensors/cameras that are configured to view a scene from different viewing directions. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 15/604475 |
| ART UNIT | 2422 — Cable and Television |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/04 (20130101) H04N 5/247 (20130101) H04N 5/0733 (20130101) H04N 7/10 (20130101) H04N 7/181 (20130101) H04N 7/0806 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10335045 | Sebe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Universita' degli Studi di Trento (University of Trento) (Trento, Italy); Fondazione Bruno Kessler (Bruno Kessler Foundation) (Trento, Italy); The Research Foundation for The State University of New York (Albany, New York); University of Pittsburgh Of The Commonwealth of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Universita degli Studi Di Trento (Trento, Italy); Fondazione Bruno Kessler (Trento, Italy); The Research Foundation for the State University of New York (Binghamton, New York); University of Pittsburgh of the Commonwealth of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Niculae Sebe (Pergine Valsugana, Italy); Xavier Alameda-Pineda (Trento, Italy); Sergey Tulyakov (Trento, Italy); Elisa Ricci (Trento, Italy); Lijun Yin (Vestal, New York); Jeffrey F. Cohn (Pittsburgh, Pennsylvania) |
| ABSTRACT | Recent studies in computer vision have shown that, while practically invisible to a human observer, skin color changes due to blood flow can be captured on face videos and, surprisingly, be used to estimate the heart rate (HR). While considerable progress has been made in the last few years, still many issues remain open. In particular, state-of-the-art approaches are not robust enough to operate in natural conditions (e.g. in case of spontaneous movements, facial expressions, or illumination changes). Opposite to previous approaches that estimate the HR by processing all the skin pixels inside a fixed region of interest, we introduce a strategy to dynamically select face regions useful for robust HR estimation. The present approach, inspired by recent advances on matrix completion theory, allows us to predict the HR while simultaneously discover the best regions of the face to be used for estimation. Thorough experimental evaluation conducted on public benchmarks suggests that the proposed approach significantly outperforms state-of-the-art HR estimation methods in naturalistic conditions. |
| FILED | Friday, June 23, 2017 |
| APPL NO | 15/631346 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/021 (20130101) A61B 5/024 (20130101) Original (OR) Class A61B 5/0077 (20130101) A61B 5/165 (20130101) A61B 5/1114 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00268 (20130101) G06K 9/00281 (20130101) G06K 9/00315 (20130101) G06K 9/4652 (20130101) G06K 2009/00939 (20130101) Image Data Processing or Generation, in General G06T 3/0093 (20130101) G06T 7/11 (20170101) G06T 7/0016 (20130101) G06T 7/90 (20170101) G06T 2207/10016 (20130101) G06T 2207/10024 (20130101) G06T 2207/30048 (20130101) G06T 2207/30201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335116 | Boctor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Emad M. Boctor (Baltimore, Maryland); Iulian I. Iordachita (Lutherville, Maryland); Xiaoyu Guo (Baltimore, Maryland); Alexis Cheng (Baltimore, Maryland); Haichong Zhang (Baltimore, Maryland); Fereshteh Aalamifar (Baltimore, Maryland) |
| ABSTRACT | According to some embodiments of the invention, a robot-assisted ultrasound system includes a first ultrasound probe, a robot comprising a manipulator arm having a tool end, and a second ultrasound probe attached to the tool end of the manipulator arm. The robot-assisted ultrasound system further includes a robot control system configured to control at least one of a position or a pose of the second ultrasound probe based on a contemporaneous position and pose of the first ultrasound probe, and an ultrasound processing and display system configured to communicate with at least one of the first and second ultrasound probes to receive and display an ultrasound image based on the first and second ultrasound probes acting in conjunction with each other. |
| FILED | Friday, April 17, 2015 |
| APPL NO | 14/690232 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/15 (20130101) A61B 8/145 (20130101) A61B 8/4209 (20130101) Original (OR) Class A61B 8/4218 (20130101) A61B 8/4263 (20130101) A61B 8/4477 (20130101) A61B 34/30 (20160201) A61B 90/50 (20160201) A61B 2034/2055 (20160201) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/47 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335342 | Alvarez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| ASSIGNEE(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| INVENTOR(S) | Tara Lynn Alvarez (Whippany, New Jersey); John Vito D'Antonio-Bertagnolli (Mount Laurel, New Jersey); Robert Gioia (Copiagne, New York); Mitchell Scheiman (Bala Cynwyd, Pennsylvania); Chang Yaramothu (Hackensack, New Jersey) |
| ABSTRACT | Exemplary embodiments of the present disclosure relate to systems, methods, and apparatus for vision therapy. In exemplary embodiments a visual therapy game can be rendered on one or more displays and the visual therapy game can be controlled by eye movements of the user. Visual stimuli incorporated in the visual therapy game can be rendered to facilitate vergence eye movements for the treatment of binocular dysfunctions. |
| FILED | Friday, July 22, 2016 |
| APPL NO | 15/746757 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/08 (20130101) A61B 3/113 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 5/00 (20130101) Original (OR) Class A61H 2201/5015 (20130101) Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 13/213 (20140902) A63F 2300/8094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335515 | Detamore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | The University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Michael Detamore (Lawrence, Kansas); Emily Beck (Lawrence, Kansas); Stevin Gehrke (Lawrence, Kansas); Cory Berkland (Lawrence, Kansas) |
| ABSTRACT | An implantable hydrogel precursor composition can include: a cross-linkable polymer matrix that is biocompatible; and a plurality of polymer particles in the cross-linkable polymer matrix. The cross-linkable polymer matrix can include a cross-linkable hyaluronic acid polymer that has cross-linkable functional groups. The hyaluronic acid polymer can be a methacrylated hyaluronic acid polymer. The methacrylated hyaluronic acid polymer can have a molecular weight from about 500 kDa to about 1.8 MDa. The polymer particles can include a cross-linked hyaluronic acid. The cross-linkable polymer matrix having the polymer particles has a yield stress. The cross-linkable polymer matrix having the polymer particles has shape retention at physiological temperatures. The composition can include live cells in the cross-linkable polymer matrix. The composition can include a biologically active agent in the cross-linkable polymer matrix. |
| FILED | Tuesday, October 20, 2015 |
| APPL NO | 14/918229 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/20 (20130101) A61L 27/48 (20130101) Original (OR) Class A61L 27/48 (20130101) A61L 27/50 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/383 (20130101) A61L 27/3817 (20130101) A61L 27/3834 (20130101) A61L 2430/06 (20130101) A61L 2430/32 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) C08L 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335946 | Hogan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Neville Hogan (Sudbury, Massachusetts); Lucille Hosford (Edmonds, Washington) |
| ABSTRACT | Described herein are concepts, techniques, and structures for robot control using compositional impedance programming. In one embodiment, a robot control system comprises a plurality of impedance modules, each of the impedance modules defining one or more mechanical impedance parameters and an impedance controller. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/435544 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1641 (20130101) Original (OR) Class B25J 9/1661 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/39201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336028 | Katz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Andrew Jason Katz (Saint Johns, Florida); Craig Lusk (Lutz, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Andrew Jason Katz (Saint Johns, Florida); Craig Lusk (Lutz, Florida) |
| ABSTRACT | The first objective of this paper is to take an existing design for a shape-shifting surface (SSS) and make it waterproof, making it an effective barrier to fluid flow. The second objective is to minimize internal stresses in the device during operation, by optimizing the kinematic geometry of the SSS. The first objective was achieved by adding a waterproof membrane between the layers of the SSS, where the membrane had an origami fold pattern that enables the membrane to mimic the kinematics of the SSS. The second objective was achieved by creating a two objective optimization routine, which determined the kinematic geometry of the SSS which would minimize the internal stresses due to compression/tension of the flexure portion of the SSS during operation. The resulting SSS is easier to operate due to lower stresses, and has a membrane which prevents transverse fluid flow and mimics its motion. |
| FILED | Thursday, July 28, 2016 |
| APPL NO | 15/222258 |
| ART UNIT | 1781 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/06 (20130101) Original (OR) Class B32B 3/266 (20130101) B32B 7/05 (20190101) B32B 7/08 (20130101) B32B 2250/04 (20130101) B32B 2307/732 (20130101) B32B 2307/7265 (20130101) Motor Vehicles; Trailers B62D 29/04 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/34 (20130101) E04B 1/665 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 11/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336062 | Sreenivasan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | S. V. Sreenivasan (Austin, Texas); Brent Snyder (Austin, Texas); Miaomiao Yang (Austin, Texas); Shrawan Singhal (Austin, Texas); Ovadia Abed (Austin, Texas) |
| ABSTRACT | Systems and methods for precision inkjet printing are disclosed. A method determining an actuation parameter associated with a pressure waveform. Based on the pressure waveform, the method also includes actuating a print head to eject a droplet from a nozzle and acquiring an image of the droplet. The method further includes processing the acquired image to estimate a volume of the droplet and based on the estimated volume of the droplet and a target volume, adjusting the actuation parameter. |
| FILED | Monday, March 13, 2017 |
| APPL NO | 15/457283 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/0456 (20130101) B41J 2/0458 (20130101) B41J 2/04508 (20130101) Original (OR) Class B41J 2/04561 (20130101) B41J 2/04581 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336465 | Rennó |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Nilton O. Rennó (Ann Arbor, Michigan) |
| ABSTRACT | Methods and systems for detecting ice crystals and volcanic ash in concentrations capable of causing power loss in aircraft jet engines. These hazard conditions are inferred from the detection of ice crystals or ash in air recently lifted from the lower atmosphere by convective updrafts. The detection systems can comprise subsystems for detecting air recently lifted from the lower troposphere by measuring radon activity along the aircrafts' flight track, as well as subsystems for detecting ice crystals or volcanic ash around the aircraft via multispectral measurements. The detection of ice crystals in air recently lifted from the lower troposphere indicates that the ice crystals are likely present in large concentration. The detection of volcanic ash in air recently lifted from lower atmosphere also indicates that volcanic ash is likely present in high concentration. These are hazards conditions that could cause power loss, jet engine flameout, and even damage jet engines. |
| FILED | Thursday, January 05, 2017 |
| APPL NO | 15/399088 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 15/20 (20130101) B64D 15/22 (20130101) B64D 43/00 (20130101) B64D 45/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/35 (20130101) G01N 33/0036 (20130101) G01N 2021/1793 (20130101) G01N 2201/12 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 8/12 (20130101) G01V 9/007 (20130101) Technologies for Adaptation to Climate Change Y02A 50/25 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336618 | Li |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wenzhi Li (Palmetto Bay, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Wenzhi Li (Palmetto Bay, Florida) |
| ABSTRACT | Methods and devices to synthesize vertically aligned carbon nanotube (VACNT) arrays directly on a catalytic conductive substrate without addition of an external metallic catalyst layer and without any pretreatment to the substrate surface using a plasma enhanced chemical vapor deposition (PECVD) method are provided. A method comprises providing a catalytic conductive substrate, that has not been pretreated through a plasma enhanced chemical vapor deposition (PECVD) method or other methods, to a PECVD device, etching the catalytic conductive substrate to form catalytically active nano-features on the surface of the catalytic conductive substrate, and growing vertically aligned carbon nanotubes on the surface of the catalytic conductive substrate, without an external metallic catalyst layer, by providing a carbon source gas to the catalytic conductive substrate. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/023038 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/162 (20170801) Original (OR) Class C01B 2202/08 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) C23C 16/0236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336721 | Jorgensen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | William L. Jorgensen (Deep River, Connecticut); Pawel Dziedzic (New Haven, Connecticut); Jose Cisneros (New Haven, Connecticut) |
| ABSTRACT | The present disclosure describes biaryl triazole compounds, as well as their compositions and methods of use. The compounds inhibit the activity of macrophage migration inhibitory factor and are useful for the treatment of diseases, e.g., inflammatory diseases and cancer. |
| FILED | Friday, February 12, 2016 |
| APPL NO | 15/550573 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 401/04 (20130101) Original (OR) Class C07D 403/04 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336737 | Sarlah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | David Sarlah (Champaign, Illinois); Lucas William Hernandez (Urbana, Illinois); Jola Pospech (Rostock, Germany) |
| ABSTRACT | Described herein is the development of an arenophile-mediated, nickel-catalyzed dearomative trans-1,2-carboamination protocol. A range of readily available aromatic compounds was converted to the corresponding dienes using Grignard reagents as nucleophiles. This strategy provided products with exclusive trans-selectivity and high enantioselectivity was observed in case of benzene and naphthalene. The utility of this methodology was showcased by controlled and stereoselective preparation of small, functionalized molecules. A concise synthesis of (+)-pancratistatin and (+)-7-deoxypancratistatin from benzene using an enantioselective, dearomative carboamination strategy has been achieved. This approach, in combination with the judicious choice of subsequent olefin-type difunctionalization reactions, permits rapid and controlled access to a hexasubstituted core. Finally, minimal use of intermediary steps as well as direct, late stage C-7 hydroxylation provides both natural products in six and seven operations. |
| FILED | Monday, June 18, 2018 |
| APPL NO | 16/011178 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2295 (20130101) B01J 2231/321 (20130101) B01J 2523/842 (20130101) B01J 2523/847 (20130101) Heterocyclic Compounds C07D 407/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336781 | Hoveyda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston College, The (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | THE TRUSTEES OF BOSTON COLLEGE (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Amir H. Hoveyda (Belmont, Massachusetts); Jason Kingsbury (Brookline, Massachusetts); Steven Garber (Brighton, Massachusetts); Brian L. Gray (Chestnut Hill, Massachusetts); John T. Fourkas (Chestnut Hill, Massachusetts) |
| ABSTRACT | Highly active, recoverable and recyclable transition metal-based metathesis catalysts and their organometallic complexes including dendrimeric complexes are disclosed, including a Ru complex bearing a 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene and styrenyl ether ligand. The heterocyclic ligand significantly enhances the catalytic activity, and the styrenyl ether allows for the easy recovery of the Ru complex. Derivatized catalysts capable of being immobilized on substrate surfaces are also disclosed. The present catalysts can be used to catalyze ring-closing metathesis (RCM), ring-opening (ROM) and cross metatheses (CM) reactions, and promote the efficient formation of various trisubstituted olefins at ambient temperature in high yield. |
| FILED | Wednesday, October 21, 2015 |
| APPL NO | 14/919299 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/462 (20130101) B01J 31/28 (20130101) B01J 31/1625 (20130101) B01J 31/1641 (20130101) B01J 31/1666 (20130101) B01J 31/1683 (20130101) B01J 31/1805 (20130101) B01J 31/2208 (20130101) B01J 31/2273 (20130101) B01J 31/2404 (20130101) B01J 31/4038 (20130101) B01J 2231/482 (20130101) B01J 2231/543 (20130101) B01J 2531/821 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/11 (20130101) Acyclic or Carbocyclic Compounds C07C 6/02 (20130101) C07C 29/00 (20130101) C07C 29/00 (20130101) C07C 29/00 (20130101) C07C 29/00 (20130101) C07C 35/06 (20130101) C07C 35/18 (20130101) C07C 35/21 (20130101) C07C 67/293 (20130101) C07C 67/293 (20130101) C07C 67/293 (20130101) C07C 69/013 (20130101) C07C 69/145 (20130101) C07C 2531/22 (20130101) C07C 2601/08 (20170501) C07C 2601/16 (20170501) Heterocyclic Compounds C07D 233/56 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0046 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 290/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/003 (20130101) Compositions of Macromolecular Compounds C08L 51/04 (20130101) C08L 51/08 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/584 (20151101) Y02P 20/588 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336790 | Belfort et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Georges Belfort (Slingerlands, New York); C. Seth Pearson (Albany, New York); Brian Murray (Troy, New York); Pankaj Sakharam Karande (Troy, Michigan); Jun Ha Kwak (Troy, New York); Kathleen A. McDonough (Albany, New York); Zachary Andrew Kloos (New Haven, Connecticut) |
| ABSTRACT | Disclosed herein are novel anti-microbial peptides with inhibitory activity against M. tuberculosis and streptococcus bacteria. Additionally, a method for designing novel anti-microbial peptides is disclosed. |
| FILED | Thursday, September 08, 2016 |
| APPL NO | 15/259942 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/38 (20130101) A01N 63/02 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/10 (20130101) A61K 45/06 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336814 | Orgel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MATRIX ODYSSEY, LLC (Northbrook, Illinois) |
| ASSIGNEE(S) | MATRIX ODYSSEY, LLC (Northbrook, Illinois) |
| INVENTOR(S) | Joseph Orgel (Northbrook, Illinois); Olga Antipova (Naperville, Illinois) |
| ABSTRACT | A collagen material having a form of thin fibrils generally free of fibril-bundling proteogylcan interactions, and a method for providing the thin fibril collagen material from native collagen fibers. The method uses proteoglycan antibodies to disassociate the proteoglycan interactions in bundled collagen fibrils to provide the constituent fibrils. The process can be used as a model for arthritis and the resulting fibrils can be used to form new extracellular matrix biomaterials and new tissues. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/257089 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 2430/40 (20130101) Peptides C07K 1/14 (20130101) C07K 14/78 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6887 (20130101) G01N 2333/78 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336896 | Zheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jie Zheng (Copley, Ohio); Qiang Chen (Jiaozuo, China PRC); Chao Zhao (Akron, Ohio) |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Jie Zheng (Copley, Ohio); Qiang Chen (Jiaozuo, China PRC); Chao Zhao (Akron, Ohio) |
| ABSTRACT | A method of forming a hybrid physically and chemically cross-linked double-network hydrogel with highly recoverable and mechanical properties in a single-pot synthesis is provided. The method comprises the steps of combining the hydrogel precursor reactants into a single pot. The hydrogel precursor reactants include water; a polysaccharide; a methacrylate monomer; an ultraviolet initiator; and a chemical crosslinker. Next the hydrogel precursor reactants are heated to a temperature higher than the melting point of the polysaccharide and this temperature is retained until the polysaccharide is in a sol state. Then the single-pot is cooled to a temperature lower than the gelation point of the polysaccharide and this temperature is retained to form a first network. Thereafter, photo-initiated polymerization of the methacrylate monomer occurs via the ultraviolet initiator to form the second network. |
| FILED | Wednesday, April 23, 2014 |
| APPL NO | 14/787041 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 37/0039 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2305/12 (20130101) C08J 2333/26 (20130101) C08J 2405/12 (20130101) C08J 2433/26 (20130101) Compositions of Macromolecular Compounds C08L 5/00 (20130101) C08L 5/00 (20130101) C08L 5/12 (20130101) C08L 5/12 (20130101) C08L 33/10 (20130101) C08L 33/26 (20130101) Original (OR) Class C08L 33/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336944 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Fanglin Chen (Irmo, South Carolina); Libin Lei (Columbia, South Carolina); Tong Liu (Columbia, South Carolina); Shumin Fang (Columbia, South Carolina) |
| ABSTRACT | A hydrocarbon generation system that combines a solid oxide electrolysis cell (SOEC) and a Fischer-Tropsch unit in a single microtubular reactor is described. This system can directly synthesize hydrocarbons from carbon dioxide and water. High temperature co-electrolysis of H2O and CO2 and low temperature Fischer-Tropsch (F-T) process are integrated in a single microtubular reactor by designation of a temperature gradient along the axial length of the microtubular reactor. The microtubular reactor can provide direct conversion of CO2 to hydrocarbons for use as feedstock or energy storage. |
| FILED | Thursday, September 21, 2017 |
| APPL NO | 15/711634 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/10 (20130101) B01J 23/78 (20130101) Acyclic or Carbocyclic Compounds C07C 1/10 (20130101) C07C 1/12 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 2/34 (20130101) C10G 2/35 (20130101) Original (OR) Class C10G 2/40 (20130101) C10G 2/50 (20130101) C10G 2/332 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/04 (20130101) C25B 9/10 (20130101) C25B 15/02 (20130101) C25B 15/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337051 | Doudna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Mitchell Ray O'Connell (Oakland, California); Alexandra East-Seletsky (San Francisco, California); Spencer Charles Knight (Berkeley, California); James Harrison Doudna Cate (Berkeley, California) |
| ABSTRACT | The present disclosure provides methods for detecting a single-stranded target RNA. The present disclosure provides methods of cleaving a precursor C2c2 guide RNA array into two or more C2c2 guide RNAs. The present disclosure provides a kit for detecting a target RNA in a sample. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/467922 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6823 (20130101) Original (OR) Class C12Q 1/6823 (20130101) C12Q 2521/327 (20130101) Technologies for Adaptation to Climate Change Y02A 50/53 (20180101) Y02A 50/54 (20180101) Y02A 50/57 (20180101) Y02A 50/58 (20180101) Y02A 50/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338000 | Gumennik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); FLIR Systems, Incorporated (Wilsonville, Oregon) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); FLIR Systems, Incorporated (Wilsonville, Oregon) |
| INVENTOR(S) | Alexander Gumennik (Brookline, Massachusetts); Alexander Mark Stolyarov (Belmont, Massachusetts); Brent Richard Schell (Stoughton, Massachusetts); Chong Hou (Cambridge, Massachusetts); Guillaume Romain Lestoquoy (Cambridge, Massachusetts); Fabien Sorin (Saintj-Sulpice, France); William Richard McDaniel, II (Worcester, Massachusetts); Yoel Fink (Brookline, Massachusetts); Aimee Rose (Cambridge, Massachusetts); John Dimitris Joannopoulos (Belmont, Massachusetts) |
| ABSTRACT | There is provided a sensor fiber including an electrically insulating material having a fiber length. At least one transduction element is disposed along at least a portion of the fiber length and is arranged for exposure to an intake species. A photoconducting element is in optical communication with the transduction element. At least one pair of electrically conducting electrodes are in electrical connection with the photoconducting element. The pair of electrodes extend the fiber length. |
| FILED | Tuesday, September 24, 2013 |
| APPL NO | 14/035933 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00721 (20130101) Manufacture, Shaping, or Supplementary Processes C03B 2201/86 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/76 (20130101) G01N 21/84 (20130101) Original (OR) Class G01N 21/7703 (20130101) G01N 2021/7753 (20130101) G01N 2021/7786 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02314 (20130101) G02B 6/4283 (20130101) G02B 6/4291 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338051 | Strano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael S. Strano (Lexington, Massachusetts); Daniel A. Heller (Rye Brook, New York); George W. Pratt (Melrose, Massachusetts); Jingqing Zhang (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods related to optical nanosensors comprising photoluminescent nanostructures are generally described. |
| FILED | Tuesday, June 06, 2017 |
| APPL NO | 15/615802 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/643 (20130101) G01N 21/6428 (20130101) G01N 21/6489 (20130101) G01N 33/227 (20130101) Original (OR) Class G01N 2201/061 (20130101) G01N 2201/068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338052 | Chekmenev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Eduard Y. Chekmenev (Brentwood, Tennessee); Roman V. Shchepin (Nashville, Tennessee) |
| ABSTRACT | Methods of detecting a sulfur-containing compound in a sample are described, for example using NMR-SABRE hyperpolarization of the sulfur-containing compounds in the sample. The methods can comprise, for example, contacting a sample comprising a sulfur-containing compound with parahydrogen and a catalyst to form a mixture. A spin order can be transferred from the parahydrogen to the sulfur-containing compound thereby hyperpolarizing the sulfur-containing compound during a temporary association of the parahydrogen, the sulfur-containing compound, and the catalyst. The methods can further comprise, for example, performing an NMR measurement on the mixture comprising the hyperpolarized sulfur-containing compound to detect the hyperpolarized sulfur-containing compound (e.g., from the hyperpolarized NMR signals. In some examples, the methods described herein can be used for detecting a sulfur-containing contaminant in a fuel. |
| FILED | Tuesday, November 29, 2016 |
| APPL NO | 15/362846 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/08 (20130101) G01N 33/287 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/282 (20130101) G01R 33/307 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339139 | Gehrke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Johannes Gehrke (Bellevue, Washington); Christoph Koch (Ecublens, Switzerland); Lucja Kot (Freeville, New York); Nitin Gupta (San Mateo, California) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Johannes Gehrke (Bellevue, Washington); Christoph Koch (Ecublens, Switzerland); Lucja Kot (Freeville, New York); Nitin Gupta (San Mateo, California) |
| ABSTRACT | A computer system and computer implemented method that obtains coordinated results from at least two queries by utilizing context data of each query. Specifically, the computer system and computer implemented method facilitates enhanced querying functionality by matching entangled queries to achieve coordinated results. |
| FILED | Monday, August 15, 2011 |
| APPL NO | 13/816382 |
| ART UNIT | 2158 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2425 (20190101) G06F 16/24554 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339706 | Black et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Michael J. Black (Providence, Rhode Island); Alexandru O. Balan (Pawtucket, Rhode Island); Alexander W. Weiss (Shirley, Massachusetts); Leonid Sigal (Pittsburgh, Pennsylvania); Matthew M. Loper (Providence, Rhode Island); Timothy S. St. Clair (Cambridge, Massachusetts) |
| ABSTRACT | A system and method of estimating the body shape of an individual from input data such as images or range maps. The body may appear in one or more poses captured at different times and a consistent body shape is computed for all poses. The body may appear in minimal tight-fitting clothing or in normal clothing wherein the described method produces an estimate of the body shape under the clothing. Clothed or bare regions of the body are detected via image classification and the fitting method is adapted to treat each region differently. Body shapes are represented parametrically and are matched to other bodies based on shape similarity and other features. Standard measurements are extracted using parametric or non-parametric functions of body shape. The system components support many applications in body scanning, advertising, social networking, collaborative filtering and Internet clothing shopping. |
| FILED | Thursday, June 14, 2018 |
| APPL NO | 16/008637 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00369 (20130101) G06K 9/6221 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0601 (20130101) Image Data Processing or Generation, in General G06T 7/75 (20170101) G06T 7/77 (20170101) G06T 17/00 (20130101) Original (OR) Class G06T 2207/10028 (20130101) G06T 2207/30196 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340108 | Graber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Lukas Graber (Tallahassee, Florida); Christopher Widener (Tallahassee, Florida); Samantha Smith (Tallahassee, Florida); Michael Steurer (Crawfordville, Florida) |
| ABSTRACT | An ultrafast electromechanical switch having a drive mechanism comprising two non-movable contacts connected to electrical feedthroughs, one actuator and one movable contact. The provided ultrafast electrical (e.g., transfer, disconnect, etc.) switch is simple, compact, clean, exhibits ultralow loss, does not require high energy to operate and is capable of being automatically reset. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196455 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 33/14 (20130101) H01H 33/28 (20130101) H01H 33/64 (20130101) H01H 33/666 (20130101) H01H 55/00 (20130101) H01H 57/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340109 | Graber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Lukas Graber (Tallahassee, Florida); Christopher Widener (Tallahassee, Florida); Samantha Smith (Tallahassee, Florida); Michael Steurer (Crawfordville, Florida) |
| ABSTRACT | An ultrafast electromechanical switch having a drive mechanism comprising three non-movable contacts, an actuator and two movable contacts. The switch further including a switching chamber to provide a self-contained environment that may consist of a high-pressure gas or a vacuum and one or more precision adjustment screws coupled to the non-movable contacts for adjusting the contact pressure. The provided ultrafast electrical (e.g., transfer, disconnect, etc.) switch is simple, compact, clean, exhibits ultralow loss, does not require high energy to operate and is capable of being automatically reset. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196800 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 33/14 (20130101) H01H 33/28 (20130101) H01H 33/64 (20130101) H01H 33/666 (20130101) H01H 55/00 (20130101) H01H 57/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340458 | Gong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xiong Gong (Hudson, Ohio); Chang Liu (Akron, Ohio); Kai Wang (Akron, Ohio) |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Xiong Gong (Hudson, Ohio); Chang Liu (Akron, Ohio); Kai Wang (Akron, Ohio) |
| ABSTRACT | Perovskite hybrid solar cells utilize a bulk heterojunction (BHJ) active layer that is formed as a composite of an organometal halide perovskite and a water soluble fullerene, such as A10C60. In alternative embodiments, the BHJ active layer may be formed as a composite of an organometal halide perovskite material and a fullerene, such as PC61BM. Thus, the fullerene acts as an electron extraction acceptor within the BHJ, allowing such solar cells to more efficiently transport the electrons from the fullerene/perovskite interface to a fullerene-based electron transport layer (ETL). As a result, increased fill factor (FF), as well as improvements in the short-circuit current density (JSC) and power conversion efficiency (PCE) are achieved by the solar cells. |
| FILED | Monday, October 31, 2016 |
| APPL NO | 15/339501 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0007 (20130101) H01L 51/0028 (20130101) H01L 51/0037 (20130101) H01L 51/0047 (20130101) Original (OR) Class H01L 51/0077 (20130101) H01L 51/4273 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340972 | Calhoun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Benton H. Calhoun (Charlottesville, Virginia); Yousef Shakhsheer (Charlottesville, Virginia); Yanqing Zhang (Charlottesville, Virginia); Alicia Klinefelter (Charlottesville, Virginia); David D. Wentzloff (Ann Arbor, Michigan); Nathan E. Roberts (Ann Arbor, Michigan); Seunghyun Oh (Jangdaedong Daejeon, South Korea) |
| ABSTRACT | An apparatus comprises a system on a chip (SoC). In some embodiments, the SoC includes a power supply circuit, a power management circuit operatively coupled to the power supply circuit, a first wireless communications circuit and a second wireless communications circuit. The first wireless communications circuit is configured to receive an RF signal and is operatively coupled to the power supply circuit and the power management circuit. The first wireless communications circuit has a net radio frequency (RF) power gain no more than unity before at least one of downconversion of the RF signal or detection of the RF signal. The second wireless communications circuit is operatively coupled to the power supply circuit and the power management circuit. |
| FILED | Monday, August 07, 2017 |
| APPL NO | 15/670386 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Transmission H04B 1/406 (20130101) Original (OR) Class H04B 1/1607 (20130101) Wireless Communication Networks H04W 4/70 (20180201) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 70/00 (20180101) Y02D 70/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10335711 | Baxter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Larry Baxter (Orem, Utah); Kyler Stitt (Lindon, Utah); Aaron Sayre (Spanish Fork, Utah); Christopher Hoeger (Provo, Utah) |
| ASSIGNEE(S) | Sustainable Energy Solutions, LLC (Orem, Utah) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); Kyler Stitt (Lindon, Utah); Aaron Sayre (Spanish Fork, Utah); Christopher Hoeger (Provo, Utah) |
| ABSTRACT | A process to prevent fouling using a desublimating heat exchanger is disclosed. An outlet stream from the desublimating heat exchanger may be split into a plurality of parallel streams. The parallel streams may be sent through other devices for performing a unit operation, and the devices for performing a unit operation may change the temperature of at least one of the parallel streams. Parallel streams of differing temperature may emerge from the devices for performing a unit operation. The parallel streams of differing temperature may be sent to a mixing chamber. A mixed stream of uniform temperature may emerge from the mixing chamber, and the mixed stream may be recycled back to the desublimating heat exchanger. The mixing chamber may be separate from the desublimating heat exchanger, or the parallel streams of differing temperature may be mixed in the desublimating heat exchanger. |
| FILED | Wednesday, April 12, 2017 |
| APPL NO | 15/485495 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 1/0094 (20130101) B01D 7/02 (20130101) Original (OR) Class B01D 53/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335755 | Shin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Youngho Shin (La Grange Highlands, Illinois); Ozgenur Kahvecioglu Feridun (Naperville, Illinois); Gregory K. Krumdick (Homer Glen, Illinois) |
| ABSTRACT | A reaction apparatus includes a hollow chamber with a stirring shaft. The chamber is maintained at a predetermined pressure and accepts at least two reactants from two storage tanks. The stirring shaft rotates around an axis and creates a reaction product. Taylor vortexes are created while the pressure minimizes the volume possession of the gas phase. The reaction product of micron and sub-micron particles is removed from the chamber and depressurized. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/976916 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 3/02 (20130101) B01J 3/04 (20130101) Original (OR) Class B01J 2203/068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336868 | Stahl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Shannon S. Stahl (Madison, Wisconsin); Mohammad Rafiee (Madison, Wisconsin) |
| ABSTRACT | Methods of selectively modifying lignin, polycarboxylated products thereof, and methods of deriving aromatic compounds therefrom. The methods comprise electrochemically oxidizing lignin using stable nitroxyl radicals to selectively oxidize primary hydroxyls on β-O-4 phenylpropanoid units to corresponding carboxylic acids while leaving the secondary hydroxyls unchanged. The oxidation results in polycarboxylated lignin in the form of a polymeric β-hydroxy acid. The polymeric β-hydroxy acid has a high loading of carboxylic acid and can be isolated in acid form, deprotonated, and/or converted to a salt. The β-hydroxy acid, anion, or salt can also be subjected to acidolysis to generate various aromatic monomers or oligomers. The initial oxidation of lignin to the polycarboxylated form renders the lignin more susceptible to acidolysis and thereby enhances the yield of aromatic monomers and oligomers obtained through acidolysis. |
| FILED | Friday, May 27, 2016 |
| APPL NO | 15/167103 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Derivatives of Natural Macromolecular Compounds C08H 6/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336937 | Worsley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Marcus A. Worsley (Hayward, California); Alexander E. Gash (Brentwood, California); Robert A. Reibold (Salida, California) |
| ABSTRACT | Disclosed here is a method for making a monolithic rare earth oxide (REO) aerogel, comprising: preparing a reaction mixture comprising at least one rare earth metal nitrate, at least one epoxide, at least one base catalyst, and at least one organic solvent; curing the mixture to produce a wet gel; drying the wet gel to produce a dry gel; and thermally annealing the dry gel to produce the monolithic REO aerogel. Also disclosed is an REO aerogel comprising a network of REO nanostructures, wherein the REO aerogel is a monolith having at least one lateral dimension of at least 1 cm, wherein the REO aerogel has a density of about 40-500 mg/cm3 and/or a BET surface area of at least about 20 m2/g, and wherein the REO aerogel is substantially free of oxychloride. |
| FILED | Thursday, March 17, 2016 |
| APPL NO | 15/073400 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/0018 (20130101) C01F 17/0043 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2006/10 (20130101) C01P 2006/12 (20130101) C01P 2006/14 (20130101) C01P 2006/16 (20130101) C01P 2006/60 (20130101) C01P 2006/80 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/50 (20130101) C04B 38/009 (20130101) C04B 38/009 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7701 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336989 | Niyogi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Krishna K. Niyogi (Oakland, California); Zhirong Li (El Cerrito, California); Rachel Dent (Berkeley, California); Graham Peers (Fort Collins, Colorado) |
| ABSTRACT | This disclosure provides Chlamydomonas violaxanthin de-epoxidase (CVDE) gene, polypeptides, and variants thereof as well as host cells that are genetically modified to express a CVDE polypeptide or variant. The disclosure additionally provides methods of producing such a genetically modified host cell and methods of using the cells , e.g., to increase zeaxanthin production. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/625798 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0055 (20130101) Original (OR) Class C12N 15/825 (20130101) C12N 15/8269 (20130101) Enzymes C12Y 110/99003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337024 | Schnell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Danny J. Schnell (Belchertown, Massachusetts); Mine O. Canakci (Granby, Massachusetts); Bibin Paulose (Amherst, Massachusetts); Michelle DaCosta Inguagiato (Wilbraham, Massachusetts) |
| ABSTRACT | A transgenic plant having enhanced photosynthesis is disclosed. The transgenic plant is transformed with a transgenic polynucleotide encoding a heterologous bicarbonate transporter. The bicarbonate transporter can be from an algae or a cyanobacterial species. The transgenic polynucleotide comprises a nucleic acid sequence encoding the bicarbonate transporter under the control of a functional plant promoter and optionally includes a chloroplast envelope targeting peptide heterologous to the bicarbonate transporter. Methods of making the transgenic plant and transgenic polynucleotide are disclosed. |
| FILED | Wednesday, December 24, 2014 |
| APPL NO | 15/109349 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Peptides C07K 14/405 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8245 (20130101) C12N 15/8247 (20130101) C12N 15/8261 (20130101) C12N 15/8269 (20130101) Original (OR) Class C12N 15/8271 (20130101) C12N 15/8273 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337030 | Moon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); U.S. Geological Survey (Reston, Virginia) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); U.S. Geological Survey (Reston, Virginia) |
| INVENTOR(S) | Ji Won Moon (Oak Ridge, Tennessee); Tommy Joe Phelps (Knoxville, Tennessee); Ronald Oremland (Brisbane, California); David E. Graham (Knoxville, Tennessee); Ilia N. Ivanov (Knoxville, Tennessee); Christopher B. Jacobs (Knoxville, Tennessee); Gyoung Gug Jang (Knoxville, Tennessee); Michelle K. Kidder (Clinton, Tennessee); Pooran C. Joshi (Knoxville, Tennessee); Beth L. Armstrong (Clinton, Tennessee) |
| ABSTRACT | A method for producing metal chalcogenide nanoparticles, the method comprising: (i) producing hydrogen chalcogenide-containing vapor from a microbial source, wherein said microbial source comprises: (a) chalcogen-reducing microbes capable of producing hydrogen chalcogenide vapor from a chalcogen-containing source; (b) a culture medium suitable for sustaining said chalcogen-reducing microbes; (c) at least one chalcogen-containing compound that can be converted to hydrogen chalcogenide vapor by said chalcogen-reducing microbes; and (d) at least one nutritive compound that provides donatable electrons to said chalcogen-reducing microbes during consumption of the nutritive compound by said chalcogen-reducing microbes; and (ii) directing said hydrogen chalcogenide-containing vapor into a metal-containing solution comprising a metal salt dissolved in a solvent to produce metal chalcogenide nanoparticles in said solution, wherein said chalcogen is sulfur or selenium, and said chalcogenide is sulfide or selenide, respectively. The invention is also directed to metal chalcogenide nanoparticle compositions produced as above and having distinctive properties. |
| FILED | Friday, July 07, 2017 |
| APPL NO | 15/643610 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/002 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337034 | Beckham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Gregg Tyler Beckham (Golden, Colorado); Christopher W. Johnson (Denver, Colorado); Derek Richard Vardon (Lakewood, Colorado); Mary Ann Franden (Centennial, Colorado) |
| ABSTRACT | This disclosure relates to compositions and methods for converting biomass to various chemical intermediates and final products including fuels. Aspects include the depolymerization of lignin, cellulose, and hemicellulose to a wide slate of depolymerization compounds that can be subsequently metabolized by genetically modified bacterium, and converted to cis,cis-muconic acid. Other aspects include the use of monometallic catalysts for converting the cis,cis-muconic acid to commodity chemicals and fuels, for example adipic acid and/or nylon. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 15/964465 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 51/36 (20130101) C07C 51/36 (20130101) C07C 51/43 (20130101) C07C 51/43 (20130101) C07C 51/47 (20130101) C07C 51/47 (20130101) C07C 55/14 (20130101) C07C 57/16 (20130101) C07C 57/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/44 (20130101) Original (OR) Class Enzymes C12Y 113/11001 (20130101) C12Y 401/01063 (20130101) C12Y 402/01118 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337038 | Lynch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARGILL, INCORPORATED (Wayzata, Minnesota) |
| ASSIGNEE(S) | CARGILL, INCORPORATED (Wayzata, Minnesota) |
| INVENTOR(S) | Michael Lynch (Durham, North Carolina); Michael Louie (Broomfield, Colorado); Shelley Copley (Boulder, Colorado); Eileen Spindler (Lafayette, Colorado); Brittany Prather (Wheat Ridge, Colorado); Matthew Lipscomb (Boulder, Colorado); Tanya Lipscomb (Boulder, Colorado); Hans Liao (Superior, Colorado); Dave Hogsett (Niwot, Colorado); Ron Evans (Louisville, Colorado) |
| ABSTRACT | This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a fatty acid or fatty acid derived product, wherein the modified microorganism produces fatty acyl-CoA intermediates via a malonyl-CoA dependent but malonyl-ACP independent mechanism. |
| FILED | Friday, July 18, 2014 |
| APPL NO | 14/904862 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/16 (20130101) C12N 9/88 (20130101) C12N 9/1029 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/40 (20130101) C12P 7/52 (20130101) C12P 7/6409 (20130101) Original (OR) Class C12P 7/6436 (20130101) Enzymes C12Y 203/0118 (20130101) C12Y 203/01194 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337088 | Saw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Cheng Kiong Saw (Livermore, California); William A. Bauer (Beavercreek, Ohio); Jor-Shan Choi (El Cerrito, California); Sumner Daniel Day (Danville, California); Joseph C. Farmer (Tracy, California) |
| ABSTRACT | A method according to one embodiment includes combining an amorphous iron-based alloy and at least one metal selected from a group consisting of molybdenum, chromium, tungsten, boron, gadolinium, nickel phosphorous, yttrium, and alloys thereof to form a mixture, wherein the at least one metal is present in the mixture from about 5 atomic percent (at %) to about 55 at %; and ball milling the mixture at least until an amorphous alloy of the iron-based alloy and the at least one metal is formed. Several amorphous iron-based metal alloys are also presented, including corrosion-resistant amorphous iron-based metal alloys and radiation-shielding amorphous iron-based metal alloys. |
| FILED | Tuesday, March 22, 2016 |
| APPL NO | 15/077819 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0003 (20130101) B22F 9/002 (20130101) B22F 9/04 (20130101) B22F 9/005 (20130101) B22F 2009/041 (20130101) B22F 2009/043 (20130101) B22F 2301/35 (20130101) Alloys C22C 33/003 (20130101) Original (OR) Class C22C 45/02 (20130101) C22C 45/006 (20130101) C22C 2200/02 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 1/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337159 | Morgan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas); Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); Washington State University (Pullman, Washington) |
| INVENTOR(S) | Cristine Morgan (College Station, Texas); Yufeng Ge (College Station, Texas); David Brown (Pullman, Washington); Ross Bricklemyer (Pullman, Washington) |
| ABSTRACT | Soil penetrometers capable of measuring soil reflectance along the direction of insertion of the penetrometer are provided. The penetrometer can house an array of sensors, such as, for example, a Vis-NIR reflectance sensor, a load cell, a displacement sensor, and a moisture sensor. The reflectance data collected using the penetrometer can allow the interpretation and quantification of soil constituents and contaminants at high vertical resolution, such as 3 cm or more. |
| FILED | Friday, June 23, 2017 |
| APPL NO | 15/631470 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 1/027 (20130101) Original (OR) Class Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) G01J 3/0208 (20130101) G01J 3/0272 (20130101) G01J 3/0291 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/8507 (20130101) G01N 33/24 (20130101) G01N 33/246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337859 | Kreitinger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bridger Photonics, Inc. (Bozeman, Montana) |
| ASSIGNEE(S) | Bridger Photonics, Inc. (Bozeman, Montana) |
| INVENTOR(S) | Aaron Kreitinger (Bozeman, Montana); Michael Thorpe (Bozeman, Montana) |
| ABSTRACT | Measurement apparatuses and methods are disclosed for generating high-precision and -accuracy gas concentration maps that can be overlaid with 3D topographic images by rapidly scanning one or several modulated laser beams with a spatially-encoded transmitter over a scene to build-up imagery. Independent measurements of the topographic target distance and path-integrated gas concentration are combined to yield a map of the path-averaged concentration between the sensor and each point in the image. This type of image is particularly useful for finding localized regions of elevated (or anomalous) gas concentration making it ideal for large-area leak detection and quantification applications including: oil and gas pipeline monitoring, chemical processing facility monitoring, and environmental monitoring. |
| FILED | Monday, March 26, 2018 |
| APPL NO | 15/936247 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 21/20 (20130101) Original (OR) Class Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 15/00 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/28 (20130101) G01M 3/38 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) G01N 21/53 (20130101) G01N 2021/1793 (20130101) G01N 2021/1795 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/00 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10338305 | Davis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Matthew A. Davis (Orange, California); Sridhar Reddy Nimma (Cumming, Georgia) |
| ASSIGNEE(S) | EATON INTELLIGENT POWER LIMITED (Dublin, Ireland) |
| INVENTOR(S) | Matthew A. Davis (Orange, California); Sridhar Reddy Nimma (Cumming, Georgia) |
| ABSTRACT | A luminaire can comprise a lightguide, a substrate to which an array of light emitting diodes is mounted, and a cover that extends over the substrate. A light-receiving edge of the lightguide can be positioned adjacent the array of light emitting diodes so that emitted light couples into the lightguide via that edge. The lightguide can guide the coupled light from the light-receiving edge to an opposing, light-emitting edge that emits the coupled light to provide illumination. The cover can comprise an aperture through which the lightguide extends, so that the cover may enclose the light-receiving edge while the light emitting edge may protrude through the aperture. |
| FILED | Monday, November 07, 2016 |
| APPL NO | 15/345217 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/0036 (20130101) G02B 6/0051 (20130101) G02B 6/0083 (20130101) Original (OR) Class G02B 6/0085 (20130101) G02B 6/0086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339067 | Eckert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Yasuko Eckert (Bellevue, Washington); Thiruvengadam Vijayaraghavan (Madison, Wisconsin); Gabriel H. Loh (Bellevue, Washington) |
| ABSTRACT | A technique for use in a memory system includes swapping a first plurality of pages of a first memory of the memory system with a second plurality of pages of a second memory of the memory system. The first memory has a first latency and the second memory has a second latency. The first latency is less than the second latency. The technique includes updating a page table and triggering a translation lookaside buffer shootdown to associate a virtual address of each of the first plurality of pages with a corresponding physical address in the second memory and to associate a virtual address for each of the second plurality of pages with a corresponding physical address in the first memory. |
| FILED | Monday, June 19, 2017 |
| APPL NO | 15/626623 |
| ART UNIT | 2131 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 12/1009 (20130101) G06F 12/1036 (20130101) Original (OR) Class G06F 2212/68 (20130101) G06F 2212/1024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340049 | Washington, II et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Aaron L. Washington, II (Aiken, South Carolina); James C. Nicholson (Aiken, South Carolina) |
| ABSTRACT | Alpha/beta radiation barrier materials and structures formed to include the barrier materials are described. Barrier materials include a matrix and particulate materials contained in the matrix. The particulates include alpha/beta radiation absorbers. Alpha/beta radiation absorbers of the barrier materials can be molecular, particulates, or defined nanostructures that are capable of absorbing incident alpha/beta particle energies. Matrix materials can include organic or inorganic materials including thermoplastic polymers, thermoset polymers, glasses, ceramics, etc. |
| FILED | Thursday, August 04, 2016 |
| APPL NO | 15/228448 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 1/08 (20130101) Original (OR) Class G21F 1/103 (20130101) G21F 1/106 (20130101) G21F 3/02 (20130101) G21F 5/015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340508 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gao Liu (Piedmont, California); Hui Zhao (Emeryville, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Gao Liu (Piedmont, California); Hui Zhao (Emeryville, California) |
| ABSTRACT | The invention demonstrates that only 2% functional conductive polymer binder without any conductive additives was successfully used with a micron-size silicon monoxide (SiO) anode material, demonstrating stable and high gravimetric capacity (>1000 mAh/g) for ˜500 cycles and more than 90% capacity retention. Prelithiation of this anode using stabilized lithium metal powder (SLMP®) improves the first cycle Coulombic efficiency of a SiO/NMC full cell from ˜48% to ˜90%. This combination enables good capacity retention of more than 80% after 100 cycles at C/3 in a lithium-ion full cell. We also demonstrate the important connection between porosity and the loading of silicon electrodes. By employing a highly porous silicon electrode, a high areal capacity (3.3 mAh/cm2) is obtained. This method works well to achieve high loading of other high-capacity alloy anodes, the state-of-art graphite anode, as well as a high loading of positive electrodes for LIBs. |
| FILED | Tuesday, June 16, 2015 |
| APPL NO | 14/741383 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/22 (20130101) H01B 1/128 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/48 (20130101) H01M 4/364 (20130101) Original (OR) Class H01M 4/366 (20130101) H01M 4/382 (20130101) H01M 4/0404 (20130101) H01M 4/483 (20130101) H01M 4/622 (20130101) H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 4/661 (20130101) H01M 10/0525 (20130101) H01M 2004/021 (20130101) H01M 2004/027 (20130101) H01M 2220/20 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10340528 — Three-dimensional ion transport networks and current collectors for electrochemical cells
| US 10340528 | Roumi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Farshid Roumi (Pasadena, California); Mahshid Roumi (Pasadena, California) |
| ABSTRACT | Provided herein are three-dimensional ion transport networks and current collectors for electrodes of electrochemical cells. Exemplary electrodes include interconnected layers and channels including an electrolyte to facilitate ion transport. Exemplary electrodes also include three dimensional current collectors, such as current collectors having electronically conducting rods, electronically conducting layers or a combination thereof. |
| FILED | Friday, December 02, 2016 |
| APPL NO | 15/368406 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/16 (20130101) H01M 4/13 (20130101) H01M 4/78 (20130101) Original (OR) Class H01M 4/80 (20130101) H01M 4/366 (20130101) H01M 4/742 (20130101) H01M 10/054 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) H01M 12/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340801 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Regents of the University of Minnesota (Minneapolis, Minnesota); ETH Zürich (Zürich, Switzerland) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Regents of the University of Minnesota (Minneapolis, Minnesota); ETH Zürich (Zürich, Switzerland) |
| INVENTOR(S) | Brian Benjamin Johnson (Seattle, Washington); Miguel Rodriguez (Golden, Colorado); Mohit Sinha (St. Paul, Minnesota); Sairaj Vijaykumar Dhople (Minneapolis, Minnesota); Florian Anton Dörfler (Zürich, Switzerland) |
| ABSTRACT | A device includes a control unit that includes an oscillator circuit. The control unit is configured to generate, based on the oscillator circuit, at least one switching signal. The device also includes a direct current (DC)-to-DC conversion circuit comprising at least one electronic switch that is operatively coupled to the control unit. The DC-to-DC conversion circuit is configured to convert, based on the at least one switching signal, a DC input voltage to a DC output voltage, and the control unit is further configured to input, to the oscillator circuit, a current signal that is generated based on a measured output current of the DC-to-DC conversion circuit. |
| FILED | Monday, May 07, 2018 |
| APPL NO | 15/973161 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Systems for Regulating Electric or Magnetic Variables G05F 1/565 (20130101) G05F 1/575 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/08 (20130101) H02M 3/157 (20130101) H02M 3/1584 (20130101) Original (OR) Class H02M 2001/0009 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10341015 | Sarovar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Mohan Sarovar (Albany, California); David Farley (Livermore, California); Daniel B. S. Soh (Pleasanton, California); Ryan Camacho (Albuquerque, New Mexico); Constantin Brif (Tracy, California) |
| ABSTRACT | Described herein are various technologies pertaining to detecting tampering of a seal based upon quantum optical communication via a communications channel comprising the seal. A plurality of pulses of light encoded with random data are transmitted on the communications channel, whereupon they are received and their data values measured. The measured data values of the pulses are then compared to the known transmitted data to determine a correlation statistic between the transmitted and received data values. Tampering with the seal can be detected based upon identifying that the correlation statistic has dropped below a threshold non-tampered level of correlation between transmitted and received values. |
| FILED | Thursday, September 29, 2016 |
| APPL NO | 15/279706 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/50 (20130101) H04B 10/70 (20130101) H04B 10/85 (20130101) H04B 10/0795 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10341096 | Lentine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Anthony L. Lentine (Albuquerque, New Mexico); Christopher DeRose (Albuquerque, New Mexico); Paul Davids (Albuquerque, New Mexico); Hong Cai (Albuquerque, New Mexico) |
| ABSTRACT | Various technologies for performing discrete-variable (DV) quantum key distribution (QKD) with integrated electro-optical circuits are described herein. An integrated DV-QKD system uses Mach-Zehnder modulators (MZMs) to modulate a polarization of photons at a transmitter and select a photon polarization measurement basis at a receiver. A transmitter of a DV-QKD system further uses phase shifters to correct for non-idealities of the MZM in output provided to a polarization beam splitter. A receiver of a DV-QKD system can use phase shifters between a polarization beam splitter and an MZM to correct for non-idealities of the polarization beam splitter and the MZM on the receiver side. |
| FILED | Monday, October 10, 2016 |
| APPL NO | 15/289601 |
| ART UNIT | 2494 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0858 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10341311 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Schweitzer Engineering Laboratories, Inc. (Pullman, Washington) |
| ASSIGNEE(S) | Schweitzer Engineering Laboratories, Inc. (Pullman, Washington) |
| INVENTOR(S) | Rhett Smith (Kuna, Idaho); Barry Jakob Grussling (Pullman, Washington) |
| ABSTRACT | The present disclosure pertains to systems and methods for selectively encrypting data flows within a software defined network (SDN). In one embodiment, a communication device may be configured to receive a plurality of unencrypted data packets. The communication device may receive from an SDN controller a criterion used to identify at least one of the unencrypted data flows to be encrypted. Based on the criterion, an encryption subsystem may generate an encrypted data flow the unencrypted data packets based on an encryption key. In some embodiments, the encryption system may parse the packets and encrypt the data payloads without encrypting the routing information associated with the packet. In other embodiments, the encryption subsystem may be configured to encapsulate and encrypt the entire unencrypted data packet. In some embodiments, the encryption subsystem may further be configured to authenticate a sending device and/or to verify the integrity of a message. |
| FILED | Monday, July 20, 2015 |
| APPL NO | 14/803755 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/06 (20130101) H04L 63/162 (20130101) H04L 63/0471 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10342128 | Shah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Kedar G. Shah (San Francisco, California); Satinderpall S. Pannu (Pleasanton, California); Vanessa Tolosa (Oakland, California); Angela C. Tooker (Dublin, California); Heeral J. Sheth (Oakland, California); Sarah H. Felix (Oakland, California); Terri L. Delima (Livermore, California) |
| ABSTRACT | Thicker electrodes are provided on microelectronic device using thermo-compression bonding. A thin-film electrical conducting layer forms electrical conduits and bulk depositing provides an electrode layer on the thin-film electrical conducting layer. An insulating polymer layer encapsulates the electrically thin-film electrical conducting layer and the electrode layer. Some of the insulating layer is removed to expose the electrode layer. |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/274363 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/0553 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) H05K 1/11 (20130101) Original (OR) Class H05K 1/097 (20130101) H05K 3/007 (20130101) H05K 3/12 (20130101) H05K 3/20 (20130101) H05K 3/28 (20130101) H05K 3/4007 (20130101) H05K 2201/099 (20130101) H05K 2201/0338 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49147 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10342165 | Iyengar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Madhusudan K. Iyengar (Woodstock, New York); Pritish R. Parida (Fishkill, New York); Mark D. Schultz (Ossining, New York) |
| ABSTRACT | A data center cooling system has an indoor portion wherein heat is absorbed from components in the data center, and an outdoor heat exchanger portion wherein outside air is used to cool a first heat transfer fluid (e.g., water) present in at least the outdoor heat exchanger portion of the cooling system during a first mode. When an appropriate time has been reached to switch from the first mode to a second mode, the outdoor heat exchanger portion of the data cooling system is switched to a second heat transfer fluid, which is a relatively low performance heat transfer fluid (compared to the first fluid). It has a second heat transfer fluid freezing point, lower than the first heat transfer fluid freezing point, and sufficiently low to operate without freezing when the outdoor air temperature drops below a first predetermined relationship with the first heat transfer fluid freezing point. |
| FILED | Monday, September 28, 2015 |
| APPL NO | 14/867161 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/00 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/2079 (20130101) H05K 7/20836 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10336637 | Saslaw et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeremy Saslaw (Cooper City, Florida); The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Jeremy Saslaw (Cooper City, Florida); Luke Roberson (Titusville, Florida) |
| ABSTRACT | A water purification system comprises a bioreaction subsystem receiving contaminated input effluent and having a gas-lift anaerobic membrane bioreactor removing urea and organic matter to create a first effluent. A light-treatment subsystem receives the first effluent and exposes the first effluent to UV light to create a second effluent free from microorganisms. A reactor subsystem fluidically connects an ammonia-reducing reactor to the UV output and receives UV-treated second effluent and has a struvite regenerator connected to the ammonia-reducing reactor output, separating ammonia from the second effluent in the ammonia-reducing reactor, and outputting the ammonia. A separation subsystem fluidically connects to the reactor output and receives the second effluent substantially free from ammonia and has a continuous electro-deionization device separating brine/salts from the second effluent to produce potable water. A closed-loop includes an ammonia-converting subsystem and a sequential fertilizer producer. |
| FILED | Monday, July 17, 2017 |
| APPL NO | 15/651737 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 5/006 (20130101) B01D 53/24 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/60 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/70 (20130101) C02F 1/325 (20130101) C02F 1/4695 (20130101) C02F 3/322 (20130101) C02F 3/2853 (20130101) C02F 9/00 (20130101) Original (OR) Class C02F 2101/16 (20130101) C02F 2101/38 (20130101) C02F 2303/04 (20130101) C02F 2305/00 (20130101) C02F 2307/00 (20130101) Phosphatic Fertilisers C05B 7/00 (20130101) Inorganic Fertilisers Not Covered by Subclasses C05B, C05C; Fertilisers Producing Carbon Dioxide C05D 1/02 (20130101) C05D 9/00 (20130101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 17/009 (20130101) C05F 17/0081 (20130101) C05F 17/0264 (20130101) Mixtures of Fertilisers Covered Individually by Different Subclasses of Class C05; Mixtures of One or More Fertilisers With Materials Not Having a Specific Fertilising Activity, e.g Pesticides, Soil-conditioners, Wetting Agents; Fertilisers Characterised by Their Form C05G 3/0064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337996 | Blagojevic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Branimir Blagojevic (Ellicott City, Maryland); Melissa Trainer (Silver Spring, Maryland); Alexander Pavlov (Crofton, Maryland) |
| ABSTRACT | The present invention relates to a Lidar surveying instrument, which is capable of detecting and discriminating laser-induced particle fluorescence of any biological or non-biological atmospheric particles. The present astrobiology sensing instrument can remotely sense and discriminate, in real-time, the bio-indicator aerosol material signatures and environmental interferents that exist in an extraterrestrial environment, such as Mars, in order to expand the search for signatures of extraterrestrial life from the planetary soil to the planetary ground level atmosphere, by performing atmospheric volume scans of hundreds of meters in a radial direction around a planetary vehicle or a spacecraft. The Lidar instrument technology of the present invention employs real-time aerosol particle detection and discrimination based on two physical variables: particle fluorescence and particle size in the bio-discrimination space. |
| FILED | Thursday, August 25, 2016 |
| APPL NO | 15/247281 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/66 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1429 (20130101) G01N 21/6486 (20130101) Original (OR) Class G01N 2015/1493 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4813 (20130101) G01S 17/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339114 | Schnase et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | John L. Schnase (Laurel, Maryland); Daniel Q. Duffy (Gambrills, Maryland); Glenn S. Tamkin (Silver Spring, Maryland); Mark McInerney (Chevy Chase, Maryland); Denis Nadeau (Baltimore, Maryland); John H. Thompson (Fairfax Station, Virginia); Scott Sinno (Atlanta, Georgia); Savannah L. Strong (Stevensville, Maryland) |
| ABSTRACT | A system, method and computer-readable storage devices for providing an interface for an analytic service for Modern-Era Retrospective Analysis for Research and Applications (MERRA) datasets. An example system for providing the service includes a data analytics platform of an assemblage of compute and storage nodes that provide a compute-storage fabric upon which high-performance parallel operations are performed over a collection of climate data stored in a distributed file system, a sequencer that transforms the climate data, a desequencer that transforms serialized block compressed sequence files between data formats. The system includes a services library of applications that dynamically create data objects from the data as reduced final results, and a utilities library of software applications that process flat serialized block compressed sequence files. The system also includes a service interface through which a client device can access the climate data via the data analytics platform. |
| FILED | Wednesday, May 13, 2015 |
| APPL NO | 14/711137 |
| ART UNIT | 2157 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/182 (20190101) G06F 16/211 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340553 | Smart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Marshall C. Smart (Studio City, California); Ratnakumar V. Bugga (Arcadia, California) |
| ABSTRACT | Provided herein are electrolytes for lithium-ion electrochemical cells, electrochemical cells employing the electrolytes, methods of making the electrochemical cells and methods of using the electrochemical cells over a wide temperature range. Included are electrolyte compositions comprising a lithium salt, a cyclic carbonate, a non-cyclic carbonate, and a linear ester and optionally comprising one or more additives. |
| FILED | Tuesday, February 16, 2016 |
| APPL NO | 15/044637 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/52 (20130101) H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 4/382 (20130101) H01M 4/386 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/583 (20130101) H01M 4/587 (20130101) H01M 6/164 (20130101) H01M 6/166 (20130101) H01M 6/168 (20130101) H01M 10/058 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 2004/027 (20130101) H01M 2004/028 (20130101) H01M 2220/20 (20130101) H01M 2300/004 (20130101) H01M 2300/0042 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/54 (20151101) Technical Subjects Covered by Former US Classification Y10T 29/49108 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10340585 | Marrero-Fontanez |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Victor J. Marrero-Fontanez (Greenbelt, Maryland) |
| ABSTRACT | Various embodiments relate to a low-profile, linearly-polarized patch antenna with parasitic elements at 5.3 GHz for the ISS C-band WiFi band. It may also use the 5.8 GHz band. A protective dome helps to meet low earth orbit space requirements. |
| FILED | Monday, July 24, 2017 |
| APPL NO | 15/657590 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 1/42 (20130101) H01Q 1/288 (20130101) Original (OR) Class H01Q 1/2291 (20130101) H01Q 5/30 (20150115) H01Q 5/385 (20150115) H01Q 7/00 (20130101) H01Q 9/0407 (20130101) H01Q 19/28 (20130101) Transmission H04B 7/195 (20130101) H04B 7/18515 (20130101) Wireless Communication Networks H04W 84/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10335406 | Jenkins |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elysium Therapeutics, Inc. (Danville, California) |
| ASSIGNEE(S) | Elysium Therapeutics, Inc. (Danville, California) |
| INVENTOR(S) | Thomas E. Jenkins (Half Moon Bay, California) |
| ABSTRACT | The invention provides pharmaceutical compositions comprising macromolecular gastrointestinal enzyme-labile opioid prodrugs, co-formulated with small-molecule and/or macromolecular gastrointestinal enzyme inhibitors. The macromolecular constructs are minimally absorbed from the GI tract, and can produce non-linear pharmacokinetic profiles of the delivered opioid agonist following oral ingestion. An optional macromolecular opioid antagonist may also be present in compositions of the invention to discourage tampering by potential abusers. |
| FILED | Thursday, October 26, 2017 |
| APPL NO | 15/795126 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/55 (20170801) A61K 47/61 (20170801) A61K 47/64 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10336768 | Cuny et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yuma Therapeutics, Inc. (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Yuma Therapeutics, Inc. (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Gregory D. Cuny (Houston, Texas); Marcie A. Glicksman (Boston, Massachusetts); Kevin J. Hodgetts (Framingham, Massachusetts); Steven L. Mathieu (Somerville, Massachusetts); Yukari Y. Perrella (Cambridge, Massachusetts); Vincent Darmency (Bougy Villars, Switzerland); Hrvoje Lusic (Boston, Massachusetts) |
| ABSTRACT | The present invention relates to 2-amino-4-arylpyrimidine and 2-amino-4-aryltriazine compounds as inhibitors of heat shock protein 90 family of chaperone proteins. The invention also features pharmaceutical compositions and kits that include the compounds and compositions of the invention. The invention further relates to the medical use of these compounds and compositions for the treatment of a disorder in a subject. For example, the disorder is a neurodegenerative disease. |
| FILED | Monday, June 15, 2015 |
| APPL NO | 15/317999 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 239/42 (20130101) C07D 239/70 (20130101) C07D 239/84 (20130101) C07D 251/16 (20130101) C07D 251/22 (20130101) C07D 405/04 (20130101) C07D 405/10 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 495/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10339387 | Beard et al. |
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| FUNDED BY |
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| APPLICANT(S) | Brigham Young University (Provo, Utah) |
| ASSIGNEE(S) | Brigham Young University (Provo, Utah) |
| INVENTOR(S) | Randal W. Beard (Orem, Utah); Peter C. Niedfeldt (Provo, Utah); James K. Ingersoll (Snohomish, Washington); Patrick Defranco (Missouri City, Texas) |
| ABSTRACT | For automated detection and tracking of multiple targets, an apparatus, method, and program product are disclosed. The apparatus includes a camera that captures video data and a processor that compensates for camera motion in the video data, processes the compensated video data to remove noise and spurious returns, detects one or more targets within the processed video data, and identifies target information for each target in the processed video data. |
| FILED | Friday, March 03, 2017 |
| APPL NO | 15/449812 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/127 (20130101) B64C 2201/141 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/40 (20130101) G06K 9/46 (20130101) G06K 9/00651 (20130101) G06K 9/00771 (20130101) Original (OR) Class G06K 9/6202 (20130101) G06K 9/6211 (20130101) G06K 2009/3291 (20130101) G06K 2209/21 (20130101) Image Data Processing or Generation, in General G06T 7/254 (20170101) G06T 7/277 (20170101) G06T 7/292 (20170101) G06T 2207/10016 (20130101) G06T 2207/10032 (20130101) G06T 2207/30212 (20130101) G06T 2207/30232 (20130101) Pictorial Communication, e.g Television H04N 5/23258 (20130101) H04N 5/23267 (20130101) H04N 7/181 (20130101) H04N 7/183 (20130101) H04N 7/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10341606 | Davey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SA Photonics, Inc. (Los Gatos, California) |
| ASSIGNEE(S) | SA Photonics, Inc. (Los Gatos, California) |
| INVENTOR(S) | James Arundell Davey (Sunnyvale, California) |
| ABSTRACT | Systems and methods of multiplexing information from a plurality of monochrome sensors/cameras is provided. The systems and methods provided can be useful to achieve pixel-level time synchronization between information acquired by different monochrome sensors/cameras that are configured to view a scene from different viewing directions. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 15/604475 |
| ART UNIT | 2422 — Cable and Television |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/04 (20130101) H04N 5/247 (20130101) H04N 5/0733 (20130101) H04N 7/10 (20130101) H04N 7/181 (20130101) H04N 7/0806 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10334857 | Blackburn et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Michael B. Blackburn (Woodbine, Maryland); Dawn E. Gundersen-Rindal (Silver Spring, Maryland); Robert R. Farrar (Bowie, Maryland); Daniel J. Kuhar (Laurel, Maryland); Ashaki D. Mitchell (Mount Airy, Maryland) |
| ABSTRACT | A novel Chromobacterium phragmitis sp. nov. strain 113-1 (NRRL B-67133) is described, which has insecticidal activity against insect larvae, in general, and dipteran and lepidopteran insect larvae, in particular. A biocontrol agent containing Chromobacterium phragmitis sp. nov. strain 113-1 (NRRL B-67133) and optionally a carrier are also described. Methods of killing insect larvae and methods of reducing insect populations in an area by applying to the area or an object an effective amount of the biocontrol agent are also described. |
| FILED | Tuesday, October 10, 2017 |
| APPL NO | 15/728901 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/006 (20130101) A01N 63/02 (20130101) Original (OR) Class A01N 65/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337067 | Kirkpatrick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Brian Wayne Kirkpatrick (Fitchburg, Wisconsin); Eui-Soo Kim (Laurel, Maryland); Chad D. Bierman (Holmen, Wisconsin) |
| ABSTRACT | Collections of polynucleotides useful for estimating breeding value or detecting likelihood of twinning are disclosed. The polynucleotides are used to detect genomic sequences quantitatively associated with the twinning trait. Also disclosed are methods and kits for using the collections to estimate breeding value or predict likelihood of twinning. |
| FILED | Wednesday, March 25, 2015 |
| APPL NO | 14/668512 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/124 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337159 | Morgan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas); Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); Washington State University (Pullman, Washington) |
| INVENTOR(S) | Cristine Morgan (College Station, Texas); Yufeng Ge (College Station, Texas); David Brown (Pullman, Washington); Ross Bricklemyer (Pullman, Washington) |
| ABSTRACT | Soil penetrometers capable of measuring soil reflectance along the direction of insertion of the penetrometer are provided. The penetrometer can house an array of sensors, such as, for example, a Vis-NIR reflectance sensor, a load cell, a displacement sensor, and a moisture sensor. The reflectance data collected using the penetrometer can allow the interpretation and quantification of soil constituents and contaminants at high vertical resolution, such as 3 cm or more. |
| FILED | Friday, June 23, 2017 |
| APPL NO | 15/631470 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 1/027 (20130101) Original (OR) Class Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) G01J 3/0208 (20130101) G01J 3/0272 (20130101) G01J 3/0291 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/8507 (20130101) G01N 33/24 (20130101) G01N 33/246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10338015 | Augustine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Madison Avenue Management Co., Inc. (Hamburg, New Jersey) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); MADISON AVENUE MANAGEMENT CO., INC. (Hamburg, New Jersey) |
| INVENTOR(S) | Matthew P. Augustine (Davis, California); Victor Lim (Walnut Creek, California); Joseph S. Broz (Alexandria, Virginia) |
| ABSTRACT | This invention relates to methods and devices for NMR spectroscopy analyzing sealed containers e.g., food and beverage containers and other containers, and particularly according to specific embodiments sealed containers made of a conducting but generally nonferromagnetic metal or other conducting material. As discussed in above referenced applications, many current strategies for contaminant detection require a container to be violated, a process that can destroy the container or product and is impractical in large scale applications. The present invention overcomes these and other problems by providing methods and devices for the detection of contaminants and/or contraband in metal or conducting containers by NMR spectroscopy. |
| FILED | Tuesday, March 04, 2014 |
| APPL NO | 14/772068 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/084 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/30 (20130101) G01R 33/4625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10341617 | Malik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Abish Malik (Northridge, California); David Scott Ebert (West Lafayette, Indiana); Hanye Xu (West Lafayette, Indiana); James Tay (West Lafayette, Indiana); Shehzad Afzal (West Lafayette, Indiana); Yung-hsiang Lu (West Lafayette, Indiana) |
| ABSTRACT | A system for determining a travel path, including a network of at least one camera, a communication hub coupled to the network of at least one camera, at least one electronic communication device, and a data processing system coupled to the communication hub, the data processing system comprising one or more processors configured to calculate a travel path based on user-specified criteria including maximum camera coverage, where the system is adapted to dynamically identify a plurality of cameras. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/468101 |
| ART UNIT | 2488 — Recording and Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04847 (20130101) G06F 16/29 (20190101) G06F 16/51 (20190101) G06F 16/951 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 45/02 (20130101) H04L 61/103 (20130101) H04L 61/6095 (20130101) H04L 67/10 (20130101) Pictorial Communication, e.g Television H04N 7/181 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/80 (20180201) H04W 84/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10335365 | Pan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents ot the Univershy of California (Oakland, California); The United States of America as represented by the Department of Veteran Affairs (Washington DC) (Washington, District of Columbia) |
| INVENTOR(S) | Chong-Xian Pan (Davis, California); Hongyong Zhang (Davis, California); Kit S. Lam (Davis, California); Olulanu H. Aina (Elk Grove, California) |
| ABSTRACT | The present invention is directed to bladder cancer specific ligand peptides, comprising the amino acid sequence X1DGRX5GF (SEQ ID NO: 1), and methods of their use, e.g., for imaging detection for diagnosis of bladder, tumor localization to guide transurethral resection of bladder cancer, imaging detection of bladder cancer for follow-up after the initial treatment that can replace or complement costly cystoscopy, imaging detection of metastatic bladder cancer, and targeted therapy for superficial and metastatic bladder cancer. |
| FILED | Saturday, January 07, 2017 |
| APPL NO | 15/400987 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) Original (OR) Class A61K 9/51 (20130101) A61K 38/00 (20130101) A61K 47/51 (20170801) A61K 47/64 (20170801) A61K 47/66 (20170801) A61K 49/0002 (20130101) A61K 49/0032 (20130101) A61K 49/0056 (20130101) A61K 51/088 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 7/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10338970 | Kirchner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Peter D. Kirchner (Putnam Valley, New York); Krzysztof P. Onak (Scarsdale, New York); Robert Saccone (Glen Head, New York); Kanthi Sarpatwar (Mohegan Lake, New York); Joel L. Wolf (Goldens Bridge, New York) |
| ABSTRACT | A method of scheduling assignment of resources to a plurality of applications includes: determining shares of the resources assigned to each application during a first period; determining shares of the resources assigned to each application during a second period that occurs after the first period; determining an imbalance value for each application that is based on a sum of the shares assigned to the corresponding application over both periods; and considering requests of the applications for resources in an order that depends on a result of comparing the imbalance values of the applications. |
| FILED | Tuesday, September 20, 2016 |
| APPL NO | 15/270975 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) Original (OR) Class G06F 9/4881 (20130101) G06F 9/5005 (20130101) G06F 9/5083 (20130101) G06F 9/5088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10335504 | Sundaram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (Saint Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | G. S. M. Sundaram (Saint Louis, Missouri); Jothilingam Sivapackiam (Saint Louis, Missouri); Vijay Sharma (Wildwood, Missouri) |
| ABSTRACT | Probes which target diffuse and fibrillar forms of amyloid beta (Aβ) are described. These probes demonstrate high initial brain penetration and facile clearance from non-targeted regions. The agents can be used to image amyloid quantitatively for monitoring efficacy of Aβ-modifying therapeutics and assist in premortem diagnosis of Alzheimer's disease (AD). Disclosed probes can bind Aβ aggregates of preformed Aβ1-42 fibrils in vitro and can be used to image fibrillar and diffuse plaques ex vivo in brain sections. Disclosed probes can be used to determine Aβ burden in early stages of AD. These probes can be used for multimodality imaging of Aβ. F-AI-187 (1 μM) can detect Aβ plaques in brain sections of APP/PS1 mice. F-AI-187 (10 μM) can detect Aβ plaques in the frontal lobe in a brain section of a patient with confirmed AD. Some probes can be used for fluorescence imaging of plaque. |
| FILED | Saturday, April 02, 2016 |
| APPL NO | 15/089516 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0453 (20130101) A61K 51/0455 (20130101) A61K 51/0459 (20130101) Original (OR) Class A61K 51/0465 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) Heterocyclic Compounds C07D 277/64 (20130101) C07D 277/66 (20130101) C07D 293/12 (20130101) C07D 417/06 (20130101) C07D 421/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1804 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/6893 (20130101) G01N 33/6896 (20130101) G01N 2333/4709 (20130101) G01N 2800/32 (20130101) G01N 2800/2821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10335759 | Ramler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey J. Ramler (Lewis Center, Ohio); Anna Lee Tonkovich (Dulbin, Ohio); Rachid Taha (Dublin, Ohio); Kai Jarosch (Bexley, Ohio); Robert J. Luzenski (Marysville, Ohio); Jeffery D. Slane (Galloway, Ohio); Thomas Hickey (Dublin, Ohio); Sean Fitzgerald (Columbus, Ohio); Harley D. Freeman (Dublin, Ohio); Frederick A. Zenz (Cold Spring, New York) |
| ASSIGNEE(S) | Velocys, Inc. (Plain City, Ohio) |
| INVENTOR(S) | Jeffrey J. Ramler (Lewis Center, Ohio); Anna Lee Tonkovich (Dulbin, Ohio); Rachid Taha (Dublin, Ohio); Kai Jarosch (Bexley, Ohio); Robert J. Luzenski (Marysville, Ohio); Jeffery D. Slane (Galloway, Ohio); Thomas Hickey (Dublin, Ohio); Sean Fitzgerald (Columbus, Ohio); Harley D. Freeman (Dublin, Ohio); Frederick A. Zenz (Cold Spring, New York) |
| ABSTRACT | The invention providing methods of loading and unloading particulate from microchannels in apparatus that contains multiple microchannels, typically apparatus that is designed to operate with hundreds or thousands of particulate-containing microchannels. Aligning a sonicating head at one end of a set of microchannels provides a particularly effective mode for densifying particulate in microchannels. |
| FILED | Wednesday, November 05, 2008 |
| APPL NO | 12/265727 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) Original (OR) Class B01J 2219/0086 (20130101) B01J 2219/00788 (20130101) B01J 2219/00822 (20130101) B01J 2219/00824 (20130101) B01J 2219/00835 (20130101) B01J 2219/00867 (20130101) B01J 2219/00873 (20130101) B01J 2219/00891 (20130101) B01J 2219/00932 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337068 | Winn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Michelle Winn (Durham, North Carolina); Margaret A. Pericak-Vance (Coral Gables, Florida); Jeffery M. Vance (Coral Gables, Florida) |
| ABSTRACT | Focal and segmental glomerulosclerosis (FSGS) is a kidney disorder of unknown etiology and up to 20% of patients on dialysis have this diagnosis. A large family with hereditary FSGS carries a missense mutation in the TRPC6 gene on chromosome 11q, encoding the ion channel protein Transient Receptor Potential Cation Channel 6. The missense mutation is a P112Q substitution, which occurs in a highly conserved region of the protein, enhances TRPC6-mediated calcium signals in response to agonists such as angiotensin II, and alters the intracellular distribution of TRPC6 protein. Previous work has emphasized the importance of cytoskeletal and structural proteins in proteinuric kidney diseases. Our findings suggest a novel mechanism for glomerular disease pathogenesis. |
| FILED | Wednesday, June 01, 2016 |
| APPL NO | 15/170916 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 31/4174 (20130101) A61K 33/24 (20130101) A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) G01N 2333/705 (20130101) G01N 2500/04 (20130101) G01N 2800/52 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10337577 | Bullard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Andrew L. Bullard (Manhattan Beach, California); Shane E. Wilson (Torrance, California); Ricardo A. Aguilera (Alhambra, California); Ryan Yates (Los Angeles, California) |
| ABSTRACT | A linear spring member having an annular region with a first thickness connected in series by cylindrical regions having a second thickness, wherein the first thickness is less than the second thickness. Outer portions of adjacent annular regions are coupled together by a first cylindrical region and inner portions of adjacent annular regions are coupled together by a second cylindrical region such that the effective spring rate of the bi-directional spring device increases symmetrically as it is displaced in either compression or tension. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/344434 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Springs; Shock-absorbers; Means for Damping Vibration F16F 1/18 (20130101) F16F 1/22 (20130101) Original (OR) Class F16F 1/025 (20130101) F16F 3/02 (20130101) F16F 2228/066 (20130101) F16F 2238/022 (20130101) Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 11/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 02, 2019.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190702.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page