FedInvent™ Patents
Patent Details for Tuesday, September 24, 2019
This page was updated on Monday, March 27, 2023 at 05:54 AM GMT
Department of Health and Human Services (HHS)
| US 10420471 | Alfano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Robert R. Alfano (Bronx, New York); Yang Pu (New York, New York); Lingyan Shi (New York, New York); Sebastião Pratavieira (São Paulo, Brazil) |
| ABSTRACT | A method is provided for deep tissue imaging using multi-photon excitation of a fluorescent agent. The fluorescent agent is irradiated with an ultrafast laser to produce an excited singlet state (Sn) which subsequently undergoes non-radiative relaxation to a first singlet state (S1). The S1 state undergoes fluorescence to the ground state S0 to produce an emission wavelength. Both the excitation and emission wavelengths are within the near infrared optical window, thereby permitting deep tissue penetration for both the incoming and outgoing signals. |
| FILED | Monday, June 09, 2014 |
| APPL NO | 14/299564 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00 (20130101) A61B 5/00 (20130101) A61B 5/0059 (20130101) A61B 5/0071 (20130101) Original (OR) Class A61B 5/0082 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/001 (20130101) A61K 49/0013 (20130101) A61K 49/0019 (20130101) A61K 49/0021 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) G01N 21/17 (20130101) G01N 21/62 (20130101) G01N 21/63 (20130101) G01N 21/6486 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420484 | Moghari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mehdi Hedjazi Moghari (Cambridge, Massachusetts); Reza Nezafat (Newton, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Mehdi Hedjazi Moghari (Cambridge, Massachusetts); Reza Nezafat (Newton, Massachusetts) |
| ABSTRACT | A system and method for producing an image of a subject with a magnetic resonance imaging (MRI) system using an adaptive gating window with constant gating efficiency is provided. Navigator data is acquired from the subject and used to produce a gating window having a defined gating efficiency value. Image data is acquired with the MRI system while measuring a position of an anatomical location within the subject. Image data is accepted or rejected based on whether the measured anatomical location is within the gating window. The gating window is updated using the measured position of the anatomical location such that a substantially constant gating efficiency value is maintained. Imaging is repeated with the updated gating window, after which the gating window is again updated. When the desired amount of image data has been acquired, an image of the subject is reconstructed. |
| FILED | Monday, February 13, 2012 |
| APPL NO | 13/372114 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420489 | Kovatchev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Boris P. Kovatchev (Charlottesville, Virginia); Stephen D. Patek (Charlottesville, Virginia); Marc D. Breton (Charlottesville, Virginia) |
| ASSIGNEE(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | Boris P. Kovatchev (Charlottesville, Virginia); Stephen D. Patek (Charlottesville, Virginia); Marc D. Breton (Charlottesville, Virginia) |
| ABSTRACT | A structure, method, and computer program product for a diabetes control system provides, but is not limited thereto, the following: open-loop or closed-loop control of diabetes that adapts to individual physiologic characteristics and to the behavioral profile of each person. An exemplary aspect to this adaptation is biosystem (patient or subject) observation and modular control. Consequently, established is the fundamental architecture and the principal components for a modular system, which may include algorithmic observers of patients' behavior and metabolic state, as well as interacting control modules responsible for basal rate, insulin boluses, and hypoglycemia prevention. |
| FILED | Friday, May 28, 2010 |
| APPL NO | 13/322943 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7275 (20130101) A61B 5/14532 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) G16H 50/20 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420523 | Hoogi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Assaf Hoogi (Mountain View, California); Daniel L. Rubin (Stanford, California) |
| ABSTRACT | Provided are methods for characterizing a feature of interest in a digital image. In certain aspects, the methods use an adaptive local window and include obtaining an initial contour for a feature of interest, defining a region of interest around the contour, and segmenting the feature of interest by iteratively selecting a size of a local window surrounding each point on the contour. Non-transitory computer readable media and systems that find use in practicing the methods of the present disclosure are also provided. |
| FILED | Tuesday, March 21, 2017 |
| APPL NO | 15/465459 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/725 (20130101) A61B 5/7267 (20130101) A61B 6/032 (20130101) A61B 6/502 (20130101) A61B 6/5217 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 7/12 (20170101) G06T 7/174 (20170101) G06T 7/194 (20170101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10116 (20130101) G06T 2207/20016 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20104 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420645 | Del Nido et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Pedro J. Del Nido (Lexington, Massachusetts); Haruo Yamauchi (Tokyo, Japan); Nikolay V. Vasilyev (Belmont, Massachusetts); Maria Jose M. Nunes Pereira (Cambridge, Massachusetts); Eoin D. O'Cearbhaill (Cambridge, Massachusetts) |
| ABSTRACT | A device for treating tricuspid regurgitation includes a shaft and a first fixation mechanism disposed on a distal end of the shaft. The first fixation mechanism is configured to anchor the device to a first cardiac tissue. The device includes a second fixation mechanism disposed on a proximal end of the shaft. The second fixation mechanism is configured to anchor the device to a second cardiac tissue. The device includes an approximation mechanism connecting the first fixation mechanism and the second fixation mechanism, wherein the approximation mechanism causes the second fixation mechanism to move along the shaft toward the first fixation mechanism to approximate the first cardiac tissue and the second cardiac tissue. |
| FILED | Friday, February 15, 2013 |
| APPL NO | 14/377560 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0401 (20130101) A61B 2017/081 (20130101) A61B 2017/00243 (20130101) A61B 2017/0406 (20130101) A61B 2017/00407 (20130101) A61B 2017/0409 (20130101) A61B 2017/0419 (20130101) A61B 2017/0451 (20130101) A61B 2017/0464 (20130101) A61B 2017/00606 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2487 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/04 (20130101) A61M 2025/0233 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420659 | Marshall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Healionics Corporation (Seattle, Washington) |
| ASSIGNEE(S) | HEALIONICS CORPORATION (Seattle, Washington) |
| INVENTOR(S) | Andrew J. Marshall (Seattle, Washington); Brandt Scanlan (Seattle, Washington); Max Maginness (Seattle, Washington); Adrienne Oda (Seattle, Washington); Michael J. Connolly (Seattle, Washington); Chad MacDonald (Seattle, Washington) |
| ABSTRACT | Provided herein are implantable devices, such as vascular grafts and access port for hemodialysis, that include a microporous sheath layer having a corrugated outer surface, and use therefore for reducing the risk of infection or stenosis. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/687404 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/06 (20130101) A61F 2/064 (20130101) A61F 2/0077 (20130101) A61F 2/91 (20130101) Original (OR) Class A61F 2/848 (20130101) A61F 2210/0076 (20130101) A61F 2220/0008 (20130101) A61F 2230/0069 (20130101) A61F 2250/0024 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3653 (20130101) A61M 1/3655 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420723 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Ramesh C. Gupta (Prospect, Kentucky); Radha Munagala (Louisville, Kentucky); Farrukh Aqil (Louisville, Kentucky); Jeyaprakash Jeyabalan (Louisville, Kentucky) |
| ABSTRACT | A composition is provided that comprises a therapeutic agent encapsulated by a milk-derived microvesicle. The compositions can include therapeutic agents such as phytochemical agents or chemotherapeutic agents, while the milk-derived microvesicle can be derived from raw milk or colostrum. Further provided are methods for isolating a microvesicle that includes the steps of obtaining an amount of milk, and subjecting the milk to a series of sequential centrifugations configured to yield greater than about 300 mg of microvesicle protein per 100 ml of milk. Methods of modifying an immune response and treating a cancer in which a milk-derived microvesicle composition is administered are also provided. |
| FILED | Friday, March 02, 2018 |
| APPL NO | 15/910322 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0043 (20130101) A61K 9/0053 (20130101) A61K 9/1276 (20130101) Original (OR) Class A61K 9/5176 (20130101) A61K 31/12 (20130101) A61K 31/337 (20130101) A61K 31/343 (20130101) A61K 31/352 (20130101) A61K 31/585 (20130101) A61K 31/704 (20130101) A61K 31/7042 (20130101) A61K 31/7048 (20130101) A61K 31/7105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420734 | Wardell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Suzanne E. Wardell (Durham, North Carolina); Erik R. Nelson (Champaign, Illinois); Donald P. McDonnell (Chapel Hill, North Carolina) |
| ABSTRACT | Disclosed herein are methods of treating subjects suffering from estrogen receptor positive cancer of the brain by administering a selective estrogen receptor degrader (SERM). Also disclosed are methods of treating a cancer that is resistant to an estrogen receptor modulator by administering a SERM. |
| FILED | Saturday, March 28, 2015 |
| APPL NO | 15/129197 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/136 (20130101) A61K 31/137 (20130101) Original (OR) Class A61K 31/137 (20130101) A61K 31/138 (20130101) A61K 31/138 (20130101) A61K 31/565 (20130101) A61K 31/565 (20130101) A61K 31/4196 (20130101) A61K 31/4196 (20130101) A61K 31/4535 (20130101) A61K 31/4535 (20130101) A61K 31/5685 (20130101) A61K 31/5685 (20130101) A61K 45/06 (20130101) A61K 2121/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 217/78 (20130101) C07C 217/84 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420742 | Puder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mark Puder (Medfield, Massachusetts); Deepika Nehra (Boston, Massachusetts); Brian Kalish (Brookline, Massachusetts) |
| ABSTRACT | Disclosed herein are compositions and methods for treating or preventing certain cancers in a subject. In certain embodiments such compositions and methods generally relate to the use of G-coupled protein receptor 40 (GPR40) agonists to inhibit the growth or induce apoptosis of certain cancer cells. The compositions and related methods disclosed herein may be used to treat subjects affected by cancers, such as melanoma, medullary thyroid carcinoma, malignant peripheral nerve sheath tumors and neuroblastoma, and to reduce the incidence of metastases in such affected subjects. |
| FILED | Thursday, September 14, 2017 |
| APPL NO | 15/704383 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/20 (20130101) A61K 31/20 (20130101) A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) A61K 31/196 (20130101) A61K 31/201 (20130101) A61K 31/201 (20130101) A61K 31/202 (20130101) Original (OR) Class A61K 31/202 (20130101) A61K 31/343 (20130101) A61K 31/343 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420751 | Sun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MedRegen, LLC (Baltimore, Maryland) |
| ASSIGNEE(S) | MedRegen, LLC (Baltimore, Maryland) |
| INVENTOR(S) | Zhaoli Sun (Perry Hall, Maryland); Xuhang Li (Clarksville, Maryland) |
| ABSTRACT | The present invention relates to the field of inflammatory bowel disease. In one aspect, the present invention provides methods for treating inflammatory bowel disease in a patient comprising administering to the patient a therapeutically effective amount of a stem cell mobilizer and an immunosuppressive agent. In particular embodiments, the present invention provides a method for treating inflammatory bowel disease in a patient comprising administering to the patient a therapeutically effective amount of an agent that mobilizes CD34+ and/or CD133+ stem cells and a low dose of an immunosuppressive agent. |
| FILED | Friday, July 31, 2015 |
| APPL NO | 14/814988 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/395 (20130101) A61K 31/436 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420752 | Markowitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Dallas, Texas) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Sanford Markowitz (Pepper Pike, Ohio); Amar Desai (Cleveland, Ohio); Joseph Ready (Carrollton, Texas) |
| ABSTRACT | A method of modulating hematopoietic stem cells and hematopoiesis includes administering to a subject in need thereof a 15-PGDH inhibitor. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 15/799307 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) A61K 31/4365 (20130101) Original (OR) Class A61K 38/193 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420753 | Androphy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Elliot J. Androphy (Indianapolis, Indiana); Kevin Hodgetts (Framingham, Massachusetts); Alyssa Nicole Calder (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed herein are compositions and methods for treatment of spinal muscular atrophy (SMA). In certain embodiments, compounds are provided that increase full-length survival of motor neuron (SMN) protein production by an SMN2 gene. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/862751 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2227/105 (20130101) A01K 2267/0318 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/422 (20130101) A61K 31/422 (20130101) A61K 31/426 (20130101) A61K 31/426 (20130101) A61K 31/427 (20130101) A61K 31/427 (20130101) A61K 31/437 (20130101) Original (OR) Class A61K 31/437 (20130101) A61K 31/444 (20130101) A61K 31/501 (20130101) A61K 31/501 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 31/4418 (20130101) A61K 31/4418 (20130101) A61K 31/4704 (20130101) A61K 31/4704 (20130101) A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 31/7125 (20130101) A61K 31/7125 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420758 | Lum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Lawrence Lum (Dallas, Texas); Chuo Chen (Dallas, Texas); Xuewu Zhang (Irving, Texas); Ozlem Kulak (Dallas, Texas); Xiaofeng Wu (Grapevine, Texas) |
| ABSTRACT | The present disclosure provides compounds that may be useful for inhibiting the Tankyrase enzyme. In some aspects, these compounds are useful in the treatment of a disease or disorder related to the misregulation of Tankyrase enzyme such as cancer, degenerative diseases, or fibrotic diseases. Also provided herein are compounds may also be used to prevent the elongation of the telomere in a cell. |
| FILED | Monday, May 02, 2016 |
| APPL NO | 15/571240 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/454 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420778 | Zon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Leonard I. Zon (Wellesley, Massachusetts); Alison M. Taylor (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates generally to methods, compositions and kits for treatment of ribosomal disorders and ribosomopathy, e.g. Diamond Blackfan anemia (DBA). In some embodiments, the invention relates to methods for the use of calmodulin inhibitors and calcium channel blockers for treatment of ribosomal disorders and ribosomopathy, e.g. Diamond Blackfan anemia (DBA). |
| FILED | Wednesday, November 08, 2017 |
| APPL NO | 15/806765 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/54 (20130101) A61K 31/145 (20130101) A61K 31/495 (20130101) A61K 31/553 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4375 (20130101) A61K 31/4418 (20130101) A61K 31/4965 (20130101) A61K 31/5415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420790 | Stayton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington); GENEVANT SCIENCES GMBH (Basel, Switzerland) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); GENEVANT SCIENCES GMBH (Basel, Switzerland) |
| INVENTOR(S) | Patrick S. Stayton (Seattle, Washington); Allan S. Hoffman (Seattle, Washington); Anthony Convertine (Seattle, Washington); Craig L. Duvall (Nashville, Tennessee); Danielle Benoit (Rochester, New York); Robert Overell (Shoreline, Washington); Paul H. Johnson (Snohomish, Washington); Anna S. Gall (Woodinville, Washington); Mary G. Prieve (Lake Forest Park, Washington); Amber E. E. Paschal (Redmond, Washington); Charbel Diab (Seattle, Washington); Priyadarsi De (Mohanpur, India) |
| ABSTRACT | Provided herein are micellic assemblies comprising a plurality of copolymers. In certain instauces, micellic assemblies provided herein are pH sensitive particles. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 15/499683 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 47/58 (20170801) A61K 47/60 (20170801) A61K 47/549 (20170801) A61K 47/6907 (20170801) A61K 48/0041 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 290/062 (20130101) C08F 293/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/111 (20130101) C12N 2320/32 (20130101) Technologies for Adaptation to Climate Change Y02A 50/463 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420792 | Ray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | The University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Anuradha Ray (Pittsburgh, Pennsylvania); Prabir Ray (Pittsburgh, Pennsylvania); Sally Ellen Wenzel (Pittsburgh, Pennsylvania); Timothy B. Oriss (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods are provided for treating corticosteroid-resistant asthma in a patient, comprising decreasing Interferon Regulatory Factor 5 (IRF5) activity in the patient. Antisense or RNA interference reagents and methods can be used to decrease IRF5 activity in the patient. |
| FILED | Friday, February 23, 2018 |
| APPL NO | 15/903505 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420801 | Fletcher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Anne Fletcher (Oakleigh South, Australia); Shannon J. Turley (West Roxbury, Massachusetts); Biju Parekkadan (Cambridge, Massachusetts) |
| ABSTRACT | A method for suppressing an immune response is provided. The method involves administration of isolated lymphoid tissue-derived suppressive stromal cells (LSSC) to a subject in need of such treatment in an amount effective to suppress the immune response in the subject. The invention also involves a method to isolate LSSC by digesting lymphoid tissue fragments using a combination of an enzyme mix and agitation and then collecting the LSSC. Pharmaceutical preparations comprising LSSC are also provided. |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 14/386535 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/26 (20130101) Original (OR) Class A61K 38/19 (20130101) A61K 38/204 (20130101) A61K 38/1866 (20130101) A61K 2035/122 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0651 (20130101) C12N 5/0669 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420825 | Rikihisa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Yasuko Rikihisa (Worthington, Ohio); Dipu Mohan-Kumar (Columbus, Ohio) |
| ABSTRACT | Disclosed are vaccines containing one or more immunogenic polypeptides derived from an EtpE protein from an Ehrlichia sp. or nucleic acid encoding these polypeptides. Also disclosed is a method for vaccinating a subject against Ehrlichia sp. that involves administering to the subject a composition comprising any of the disclosed vaccines. Also disclosed is a method for diagnosing and/or monitoring the treatment of Ehrlichiosis in a subject that comprising assaying a biological sample (e.g., blood, serum, or plasma sample) from the subject for the presence of an antibody that specifically binds an EtpE polypeptide. Also disclosed are methods for delivering a therapeutic or diagnostic agent to a cell in a subject that involves conjugating the agent, or a delivery vehicle comprising the agent, to polypeptide containing the C-terminal domain of an EtpE protein. |
| FILED | Friday, January 11, 2019 |
| APPL NO | 16/245904 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0233 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 47/646 (20170801) Peptides C07K 14/29 (20130101) C07K 2319/80 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 33/56911 (20130101) G01N 2333/29 (20130101) G01N 2469/20 (20130101) G01N 2800/52 (20130101) Technologies for Adaptation to Climate Change Y02A 50/403 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420826 | Valentino et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| INVENTOR(S) | Michael Valentino (Boston, Massachusetts); Michael S. Gilmore (Boston, Massachusetts) |
| ABSTRACT | Compositions comprising antigenic peptides, and their use in inducing an immunoprotective response in a subject against an infection with Streptococcus pneumonia, or for treating or preventing, i.e., reducing risk of, an infection of Streptococcus pneumonia. |
| FILED | Tuesday, November 10, 2015 |
| APPL NO | 15/524576 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/092 (20130101) Original (OR) Class Peptides C07K 14/3156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420829 | Caldwell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | Harlan D. Caldwell (Hamilton, Montana); Deborah Crane (Hamilton, Montana) |
| ABSTRACT | Compositions and methods for the treatment of Chlamydial infection are disclosed. The compositions provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions, vaccines and diagnostic kits are also disclosed. |
| FILED | Monday, February 15, 2016 |
| APPL NO | 15/043975 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/118 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/505 (20130101) A61K 2039/575 (20130101) A61K 2039/5158 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/295 (20130101) C07K 16/125 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420833 | Trent et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | M. Stephen Trent (Cedar Park, Texas); Joseph M. Boll (Austin, Texas) |
| ABSTRACT | Engineered bacteria are provided that produce modified lipid A and a polypeptide or polysaccharide antigens. In some aspects, immunogenic compositions are provided comprising a modified a lipid A and a polypeptide or polysaccharide antigen. |
| FILED | Monday, May 18, 2015 |
| APPL NO | 15/311233 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/107 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/62 (20130101) A61K 2039/70 (20130101) A61K 2039/522 (20130101) A61K 2039/575 (20130101) A61K 2039/5252 (20130101) A61K 2039/6006 (20130101) A61K 2039/6087 (20130101) A61K 2039/55572 (20130101) A61K 2039/55583 (20130101) Peptides C07K 14/005 (20130101) C07K 14/195 (20130101) C07K 2319/03 (20130101) C07K 2319/21 (20130101) C07K 2319/42 (20130101) C07K 2319/91 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/1081 (20130101) C12N 15/52 (20130101) C12N 2760/16022 (20130101) C12N 2760/16034 (20130101) C12N 2760/16071 (20130101) C12N 2760/16134 (20130101) Enzymes C12Y 204/99019 (20150701) Technologies for Adaptation to Climate Change Y02A 50/401 (20180101) Y02A 50/407 (20180101) Y02A 50/466 (20180101) Y02A 50/484 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420834 | Kwong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Institute for Research in Biomedicine (Bellinzona, Switzerland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Institute for Research in Biomedicine (Bellinzona, Switzerland) |
| INVENTOR(S) | Peter Kwong (Washington, District of Columbia); Michael Gordon Joyce (Washington, District of Columbia); Baoshan Zhang (Bethesda, Maryland); Yongping Yang (Potomac, Maryland); Peter Collins (Kensington, Maryland); Ursula Buchholz (Bethesda, Maryland); Davide Corti (Bellinzona, Switzerland); Antonio Lanzavecchia (Bellinzona, Switzerland); Guillaume Stewart-Jones (Bethesda, Maryland) |
| ABSTRACT | Metapneumovirus (MPV) F proteins stabilized in a prefusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the MPV F proteins and/or nucleic acid molecules can be used to generate an immune response to MPV in a subject. In additional embodiments, the therapeutically effective amount of the MPV F ectodomain trimers and/or nucleic acid molecules can be administered to a subject in a method of treating or preventing MPV infection. |
| FILED | Thursday, December 24, 2015 |
| APPL NO | 15/539640 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 39/155 (20130101) Original (OR) Class A61K 48/00 (20130101) Peptides C07K 14/005 (20130101) C07K 14/135 (20130101) C07K 2319/70 (20130101) C07K 2319/73 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/18322 (20130101) C12N 2760/18334 (20130101) C12N 2760/18522 (20130101) C12N 2760/18534 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420838 | Chang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Methodist Hospital (Houston, Texas) |
| ASSIGNEE(S) | The Methodist Hospital (Houston, Texas) |
| INVENTOR(S) | Jenny Chee Ning Chang (Houston, Texas) |
| ABSTRACT | Disclosed are methods for treating one or more mammalian cancers, and in particular, methods for treating human melanoma, or a head or neck cancer, that employ therapeutically-effective amounts of one or more iNOS pathway-inhibitory compounds, either alone, or in combination with one or more selected antihypertensive agents (including, for example, calcium channel antagonists), alone, or further in combination with one or more conventional chemotherapeutic agents. Also disclosed are pharmaceutical formulations that comprise these compositions, as well as methods for their use in treating refractory, metastatic, and/or relapsed cancers, or, for use in the management or reversal of treatment resistance in one or more such mammalian cancers. |
| FILED | Wednesday, April 12, 2017 |
| APPL NO | 15/486183 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/155 (20130101) A61K 31/198 (20130101) A61K 31/198 (20130101) A61K 31/223 (20130101) A61K 31/277 (20130101) A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/444 (20130101) A61K 31/496 (20130101) A61K 31/554 (20130101) A61K 31/675 (20130101) A61K 31/4422 (20130101) A61K 31/4422 (20130101) A61K 31/4427 (20130101) A61K 31/4439 (20130101) A61K 33/24 (20130101) A61K 39/0011 (20130101) A61K 39/395 (20130101) Original (OR) Class A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420840 | Hickey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RLL, LLC (Lutherville, Maryland) |
| ASSIGNEE(S) | RLL, LLC (Lutherville, Maryland) |
| INVENTOR(S) | Robert J. Hickey (Lakeview Terrace, California); Linda H. Malkas (Lakeview Terrace, California) |
| ABSTRACT | The invention described herein pertains to anticancer therapeutic agents that exhibit preferential cytotoxicity to malignant cells that express a cancer specific isoform of proliferating cell nuclear antigen (caPCNA) compared to cytotoxicity to comparable non-malignant cells, pharmaceutical compositions comprising the agents, and their use in cancer therapy. |
| FILED | Friday, April 10, 2015 |
| APPL NO | 14/684259 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 45/06 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420918 | Rodgers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Victor G. J. Rodgers (Riverside, California); Devin Binder (Riverside, California); Devin McBride (Riverside, California); Michael Hsu (Riverside, California); B. Hyle Park (Riverside, California) |
| ABSTRACT | The invention provides compositions and methods for the treatment and/or reversal of an edema, e.g., including a central nervous system (CNS) edema, e.g., a brain or a spinal edema, edema in a burned or an injured tissue such as skin, or any tissue edema. In alternative embodiments, the invention provides compositions and methods for a direct treatment and reversal of an edema, e.g., CNS, brain or spinal edema, including a membrane transport device, in vitro and in vivo characterization of edema, and the sensitive early optical detection of the edema, e.g., tissue, CNS or cerebral edema. |
| FILED | Wednesday, November 12, 2014 |
| APPL NO | 14/539385 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/4878 (20130101) A61B 5/6868 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/38 (20130101) A61K 38/40 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/16 (20130101) A61L 29/043 (20130101) A61L 29/044 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 27/002 (20130101) Original (OR) Class A61M 2027/004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420922 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Seung Yun Yang (Allston, Massachusetts); Jeffrey M. Karp (Brookline, Massachusetts); Eoin D. O'Cearbhaill (Cambridge, Massachusetts); Bohdan Pomahac (Dover, Massachusetts) |
| ABSTRACT | This disclosure relates to swellable needles that include a proximal end portion and a swellable distal end portion. Upon exposure to a liquid, the needles are configured to undergo a shape change from a first configuration in which the width of the needle is tapered from the proximal end portion to the distal end portion to a second configuration in which the distal end portion is more swollen than the proximal end portion. The swellable needles can be double layer swellable needles or single material swellable needles. |
| FILED | Friday, January 31, 2014 |
| APPL NO | 14/761504 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/08 (20130101) A61B 17/064 (20130101) A61B 2017/0641 (20130101) A61B 2017/00893 (20130101) A61B 2017/00898 (20130101) A61B 2017/06176 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0023 (20130101) A61M 2037/0046 (20130101) A61M 2037/0053 (20130101) A61M 2037/0061 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 22/00 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/18 (20130101) B32B 37/142 (20130101) B32B 38/0012 (20130101) B32B 2535/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/1043 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421070 | Chiu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Daniel T. Chiu (Seattle, Washington); Dawn E. Cohen (Seattle, Washington); Gavin D. M. Jeffries (Seattle, Washington) |
| ABSTRACT | Embodiments of the present invention relate to methods and apparatuses for the discretization and manipulation of sample volumes that is simple, robust, and versatile. It is a fluidic device that partitions a sample by exploiting the interplay between fluidic forces, interfacial tension, channel geometry, and the final stability of the formed droplet and/or discretized volume. These compartmentalized volumes allow for isolation of samples and partitioning into a localized array that can subsequently be manipulated and analyzed. The isolation of the discretized volumes along with the device's inherent portability render our invention versatile for use in many areas, including but not limited to PCR, digital PCR, biological assays for diagnostics and prognostics, cancer diagnosis and prognosis, high throughput screening, single molecule and single cell reactions or assays, the study crystallization and other statistical processes, protein crystallization, drug screening, environmental testing, and the coupling to a wide range of analytical detection techniques for biomedical assays and measurements. The minimal fluid interconnects and simple flow geometry makes the device easy to use and implement, economical to fabricate and operate, and robust in its operations. |
| FILED | Tuesday, September 29, 2015 |
| APPL NO | 14/869871 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 7/52 (20130101) B01L 2200/0642 (20130101) B01L 2200/0673 (20130101) B01L 2300/165 (20130101) B01L 2300/0877 (20130101) B01L 2300/0883 (20130101) B01L 2300/1827 (20130101) B01L 2300/1861 (20130101) B01L 2400/0439 (20130101) B01L 2400/0633 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/08 (20130101) G01N 35/10 (20130101) G01N 2035/00356 (20130101) G01N 2035/1032 (20130101) G01N 2035/1034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421696 | Stoltz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Brian M. Stoltz (San Marino, California); Yoshitaka Numajiri (Kamakura, Japan); Beau P. Pritchett (Pasadena, California); Koji Chiyoda (Gotenba, Japan) |
| ABSTRACT | This invention provides enantioenriched Mannich adducts with quaternary stereogenic centers and novel methods of preparing the compounds. Methods include the method for the preparation of a compound of formula (I): comprising treating a compound of formula (II): with a transition metal catalyst under alkylation conditions. |
| FILED | Thursday, December 17, 2015 |
| APPL NO | 14/972475 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 53/00 (20130101) Original (OR) Class C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 233/76 (20130101) C07C 271/18 (20130101) C07C 271/50 (20130101) C07C 311/16 (20130101) C07C 2601/08 (20170501) C07C 2601/14 (20170501) C07C 2601/18 (20170501) C07C 2602/10 (20170501) Heterocyclic Compounds C07D 209/88 (20130101) C07D 211/74 (20130101) C07D 211/76 (20130101) C07D 265/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421718 | Messick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Troy E. Messick (Upper Darby, Pennsylvania); Garry R. Smith (Royersford, Pennsylvania); Allen B. Reitz (Lansdale, Pennsylvania); Paul M. Lieberman (Wynnewood, Pennsylvania); Mark E. McDonnell (Lansdale, Pennsylvania); Yan Zhang (Fort Washington, Pennsylvania); Venkata Velvadapu (Ankeny, Iowa) |
| ABSTRACT | Pharmaceutical compositions of the invention comprise EBNA1 inhibitors useful for the treatment of diseases caused by EBNA1 activity such as cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and rheumatoid arthritis. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by lytic Epstein-Barr Virus (EBV) infection. |
| FILED | Thursday, November 16, 2017 |
| APPL NO | 15/814600 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/192 (20130101) A61K 31/404 (20130101) A61K 31/496 (20130101) A61K 31/4439 (20130101) Acyclic or Carbocyclic Compounds C07C 53/18 (20130101) C07C 63/66 (20130101) C07C 65/19 (20130101) C07C 65/28 (20130101) C07C 211/27 (20130101) C07C 217/84 (20130101) C07C 229/56 (20130101) C07C 229/64 (20130101) C07C 233/11 (20130101) C07C 233/64 (20130101) C07C 233/65 (20130101) C07C 235/58 (20130101) C07C 255/54 (20130101) C07C 255/55 (20130101) C07C 311/08 (20130101) C07C 311/16 (20130101) C07C 311/17 (20130101) C07C 317/14 (20130101) C07C 317/44 (20130101) C07C 2601/02 (20170501) Heterocyclic Compounds C07D 207/08 (20130101) C07D 207/12 (20130101) C07D 207/14 (20130101) C07D 207/16 (20130101) C07D 207/327 (20130101) Original (OR) Class C07D 209/08 (20130101) C07D 211/70 (20130101) C07D 213/55 (20130101) C07D 213/64 (20130101) C07D 213/74 (20130101) C07D 215/14 (20130101) C07D 231/12 (20130101) C07D 235/06 (20130101) C07D 239/26 (20130101) C07D 249/06 (20130101) C07D 277/30 (20130101) C07D 295/155 (20130101) C07D 307/79 (20130101) C07D 333/54 (20130101) C07D 401/04 (20130101) C07D 401/10 (20130101) C07D 403/10 (20130101) C07D 409/10 (20130101) C07D 417/10 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421720 | Petrukhin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Konstantin Petrukhin (New Windsor, New York); Christopher Cioffi (Albany, New York); Graham Johnson (Sanbornton, New Hampshire); Nicoleta Dobri (New York, New York); Emily Freeman (Albany, New York); Ping Chen (Albany, New York); Michael Conlon (Albany, New York); Lei Zhu (Albany, New York) |
| ABSTRACT | The present invention provides Octahydrocyclopentapyrrole compounds having the structure: (structurally represented) wherein psi is absent or present, and when present is a bond; R1, R2, R3, R4, and R5 are each independently H, halogen, CF, or C1-C4 alkyl; R6 is absent or present, and when present is H, OH, or halogen; A is absent or present, and when present is C(O) or C(O)NH; B is substituted or unsubstituted monocycle, bicycle, heteromonocycle, heterobicycle, benzyl, CO2H or (C1-C4 alkyl)-CO2H, wherein when B is CO2H, then A is present and is C(O); and when psi is present, then R6 is absent and when psi is absent, then R6 is present, or a pharmaceutically acceptable salt thereof, for treatment of diseases characterized by excessive lipofuscin accumulation in the retina. |
| FILED | Monday, March 26, 2018 |
| APPL NO | 15/935918 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/454 (20130101) Heterocyclic Compounds C07D 209/02 (20130101) C07D 209/52 (20130101) Original (OR) Class C07D 401/04 (20130101) C07D 401/06 (20130101) C07D 401/12 (20130101) C07D 403/04 (20130101) C07D 403/06 (20130101) C07D 403/12 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 498/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421722 | Tu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhude Tu (St. Louis, Missouri); Zonghua Luo (St. Louis, Missouri); Hui Liu (St. Louis, Missouri); Hongjun Jin (St. Louis, Missouri); Stanley M. Parsons (Santa Barbara, California) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zhude Tu (St. Louis, Missouri); Zonghua Luo (St. Louis, Missouri); Hui Liu (St. Louis, Missouri); Hongjun Jin (St. Louis, Missouri); Stanley M. Parsons (Santa Barbara, California) |
| ABSTRACT | The present invention generally relates to various compounds that are useful as vesicular acetylcholine transporter (VAChT) ligands. The invention further relates to methods of using these compounds and their radiolabeled analogs for the detection of neurodegenerative diseases including Parkinson's disease (PD), and Alzheimer's disease (AD). |
| FILED | Monday, June 12, 2017 |
| APPL NO | 15/620263 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 51/0455 (20130101) A61K 51/0457 (20130101) A61K 51/0497 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) C07B 2200/05 (20130101) Heterocyclic Compounds C07D 211/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421723 | Du et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Baruch S. Blumberg Institute (Doylestown, Pennsylvania) |
| ASSIGNEE(S) | BARUCH S. BLUMBERG INSTITUTE (, None) |
| INVENTOR(S) | Yanming Du (Cheshire, Connecticut); Jinhong Chang (Chalfont, Pennsylvania); Timothy Michael Block (Doylestown, Pennsylvania) |
| ABSTRACT | Described herein are alkylated imino sugars derivatives having a disease-modifying action in the treatment of diseases associated with glucosidase activity that include viral hemorrhagic fevers and other enveloped viruses, and any other diseases involving glucosidase activity. |
| FILED | Thursday, April 20, 2017 |
| APPL NO | 15/492652 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/13 (20130101) A61K 31/45 (20130101) Heterocyclic Compounds C07D 211/36 (20130101) C07D 211/40 (20130101) Original (OR) Class C07D 419/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421741 | Hoekstra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mycovia Pharmaceuticals, Inc. (Durham, North Carolina); The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | Mycovia Pharmaceuticals, Inc. (Durham, North Carolina); The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | William J. Hoekstra (Durham, North Carolina); Christopher M. Yates (Raleigh, North Carolina); Mark Behnke (Poolesville, Maryland); Asaf Alimardanov (North Bethesda, Maryland); Scott A. David (Huntsburg, Ohio); Douglas Franklin Fry (Euclid, Ohio) |
| ABSTRACT | The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof. |
| FILED | Monday, July 09, 2018 |
| APPL NO | 16/030228 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 213/30 (20130101) C07D 213/38 (20130101) C07D 213/50 (20130101) C07D 213/56 (20130101) C07D 401/06 (20130101) Original (OR) Class C07D 405/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421753 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Jiewen Zhu (Irvine, California); Wen-Hwa Lee (Newport Coast, California); Hongyuan Chen (Irvine, California); Xuning Guo (Irvine, California); Xiao-Long Qiu (Haimen, China PRC) |
| ABSTRACT | The present invention includes novel RAD51 inhibitors. The compounds of the invention may be useful in preventing or treating cancer in a subject in need thereof. The present invention also includes methods of preventing or treating cancer in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of the invention. |
| FILED | Tuesday, March 01, 2016 |
| APPL NO | 15/554829 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 209/44 (20130101) C07D 223/16 (20130101) C07D 277/56 (20130101) C07D 401/04 (20130101) C07D 403/04 (20130101) C07D 417/04 (20130101) Original (OR) Class C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421758 | Chiosis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Gabriela Chiosis (New York, New York); Pengrong Yan (New York, New York); Pallav Patel (Fresh Meadows, New York); Hardik J. Patel (Kew Gardens, New York); Tony Taldone (Forest Hills, New York); Chenghua Yang (New York, New York); Weilin Sun (Princeton, New Jersey); Stefan O. Ochiana (New York, New York) |
| ABSTRACT | The disclosure relates to novel selective Grp94 inhibitors, compositions comprising an effective amount of such compounds, and methods to treat or prevent a condition, such as cancer, comprising administering to an animal in need thereof an effective amount of such compounds. |
| FILED | Friday, August 15, 2014 |
| APPL NO | 14/912082 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 473/34 (20130101) Original (OR) Class C07D 519/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 35/00 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/60 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421773 | Parhami et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Farhad Parhami (Los Angeles, California); Frank Stappenbeck (Los Angeles, California); Brian T. Chamberlain (Los Angeles, California) |
| ABSTRACT | Oxysterol-bisphosphonate and oxysterol-alendronic acid compounds, compositions including them, and methods using them for the treatment of bone disorders. |
| FILED | Friday, May 01, 2015 |
| APPL NO | 15/302154 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/32 (20130101) Steroids C07J 7/002 (20130101) C07J 9/00 (20130101) C07J 41/0055 (20130101) Original (OR) Class C07J 43/003 (20130101) C07J 51/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421778 | Marshall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Garland R. Marshall (Clayton, Missouri); George B. Kyei (St. Louis, Missouri); Michael D. Onken (St. Louis, Missouri); Lee Ratner (St. Louis, Missouri); Nandarapu Damodara Reddy (St. Louis, Missouri) |
| ABSTRACT | Isoform-selective lysine deacetylase inhibitors are described. Inhibitors of the lysine deacetylase enzyme are useful as antitumor drugs and for treating addiction, asthma, cardio-vascular disease, immunosuppression, neurodegenerative diseases, sepsis, sickle-cell disease, uveal melanoma and termination of viral latency, particularly HIV-1 latency. |
| FILED | Thursday, May 05, 2016 |
| APPL NO | 15/570967 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 35/00 (20180101) Peptides C07K 5/0202 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421783 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kun Cheng (Kansas City, Missouri); Wei Jin (Kansas City, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Kun Cheng (Kansas City, Missouri); Wei Jin (Kansas City, Missouri) |
| ABSTRACT | Described herein is the discovery of novel PSMA-specific peptides, which were identified through a novel combinatorial biopanning method. One of the novel PSMA-specific peptides discovered, GTIQPYPFSWGY (or GTI) (SEQ ID NO: 2), exhibits high binding affinity and selectivity to PSMA and PSMA-positive prostate cancer cells. It was found that GTI can mediate internalization of the apoptotic KLA peptide (SEQ ID NO: 10) to PSMA-positive LNCaP cells and induce cell death. Moreover, a FAM-labeled GTI peptide shows a high and specific tumor uptake in nude mice bearing human prostate cancer xenografts. It was demonstrated that the GTI peptide can be employed as a PSMA-specific ligand for prostate cancer diagnosis and/or for targeted drug delivery to prostate cancer cells. |
| FILED | Monday, February 20, 2017 |
| APPL NO | 15/437248 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/10 (20130101) A61K 49/00 (20130101) A61K 49/0043 (20130101) A61K 49/0052 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 2319/33 (20130101) C07K 2319/035 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57434 (20130101) G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421789 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington, Center for Commercialization (Seattle, Washington); The Scripps Research Institute (La Jolla, California); International AIDS Vaccine Initiative (New York, New York) |
| ASSIGNEE(S) | University of Washington, Center for Commercialization (Seattle, Washington); The Scripps Research Institute (La Jolla, California); International AIDS Vaccine Initiative (New York, New York) |
| INVENTOR(S) | Po-Ssu Huang (Seattle, Washington); Joseph Graham Jardine (Seattle, Washington); Sergey V. Menis (Bothell, Washington); William Ray Schief (Encinitas, California); Neil P. King (Seattle, Washington) |
| ABSTRACT | The invention relates to an engineered outer domain (eOD) of HIV gp120 and mutants thereof and methods of making and using the same. The mutant eODs may be advantageous for the elicitation of CD4-binding site (CD4bs)-directed broadly-neutralizing antibodies (bnAbs) and/or improve binding to mature VRC01 and/or improve binding to germline VRC01 and the germlines of other VH1-2 derived broadly-neutralizing antibodies. The mutant eODs may also include glycan-masking mutations on eOD. The present invention also includes fusions of eOD to various protein multimers to enhance immunogenicity as well as the design of cocktails of different eODs that represent the full diversity of HIV sequences within the VRC01 epitope and surroundings. |
| FILED | Monday, March 04, 2019 |
| APPL NO | 16/291726 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421800 | Gladwin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Mark T. Gladwin (Pittsburgh, Pennsylvania); Jesus Tejero Bravo (Pittsburgh, Pennsylvania) |
| ABSTRACT | Described herein is a new antidote for the rapid elimination of carbon monoxide from hemoglobin, including brain, heart, and red cell hemoglobin. The disclosed therapy involves the use of modified human globins, particularly neuroglobins modified at residue 64 and cytoglobins modified at residue 81, which bind carbon monoxide with extremely high affinity. The monomeric mutant globins are infused into blood, where they rapidly and irreversibly sequester carbon monoxide, and thus limit toxic effects of carbon monoxide on cellular respiration and oxygen transport and utilization. |
| FILED | Friday, October 06, 2017 |
| APPL NO | 15/726779 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/00 (20130101) A61K 38/41 (20130101) Peptides C07K 14/795 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421801 | Chakrabarty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ananda M Chakrabarty (Villa Park, Illinois); Tapas K Das Gupta (River Forest, Illinois); Vasu Punj (Chicago, Illinois); Olga Zaborina (Brookfield, Illinois); Yoshinori Hiraoka (Chicago, Illinois); Tohru Yamada (Oak Park, Illinois) |
| ABSTRACT | Cytotoxic factors having use in modulating cell death, and their use in methods of treating necrosis or apoptosis-related conditions are disclosed. The invention also relates to methods for identifying active agents useful in treating conditions related to cell death or uncontrolled growth. The present inventors have found that different microorganisms produce different cytotoxic factor(s) having anticancer activity. The substantially pure cytotoxic factors can be used in a method of treating an infectious disease or a cancer. |
| FILED | Friday, November 08, 2013 |
| APPL NO | 14/075994 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) A61K 38/168 (20130101) A61K 38/415 (20130101) Peptides C07K 14/80 (20130101) Original (OR) Class C07K 14/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421802 | Dimitrov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Versitech Limited (Hong Kong, China Hong Kong) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Veritech Limited (Hong Kong, China Hong Kong) |
| INVENTOR(S) | Dimiter S. Dimitrov (Frederick, Maryland); Tianlei Ying (Frederick, Maryland); Tina W. Ju (Ashburn, Virginia); Kwok Yung Yuen (Hong Kong, China PRC) |
| ABSTRACT | The invention provides polypeptides (e.g., antibodies) and fusion proteins that target a epitope in the receptor binding domain (RBD) of the spike (S) glycoprotein of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV). The polypeptides and fusion proteins can be used to treat and prevent MERS-CoV infection in mammals. |
| FILED | Thursday, October 16, 2014 |
| APPL NO | 15/030165 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) Peptides C07K 14/005 (20130101) C07K 16/10 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/526 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/20033 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) G01N 2469/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421803 | Nussenzweig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Michel Nussenzweig (New York, New York); Pamela J. Bjorkman (La Canada Flintridge, California); Louise Scharf (Porter Ranch, California); Johannes Scheid (New York, New York) |
| ABSTRACT | The present invention relates to broadly neutralizing anti-HIV-1 antibodies and isolated antigens. Also disclosed are related methods and compositions. |
| FILED | Friday, January 30, 2015 |
| APPL NO | 15/115547 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 39/42 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 14/005 (20130101) C07K 16/1063 (20130101) Original (OR) Class C07K 2299/00 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) G01N 2333/162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421812 | Broering et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Teresa Broering (Brookline, Massachusetts); Colby Souders (North Weymouth, Massachusetts); Gregory Babcock (Marlborough, Massachusetts); Naomi Boatright (Quincy, Massachusetts) |
| ABSTRACT | Aspects of the present disclosure relate to binding agents (e.g., antibodies and antigen binding fragments) that bind soluble fms-like tyrosine kinase 1 (sFlt1) in an isoform specific manner. In some embodiments, immunological assay methods utilizing isoform-specific antibodies or antigen binding fragments that bind sFlt1 isoforms are provided for assessing biological samples obtained from pregnant subjects, e.g., for purposes of evaluating preeclampsia status in the subject. |
| FILED | Thursday, March 31, 2016 |
| APPL NO | 15/086445 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) Peptides C07K 16/40 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/689 (20130101) G01N 2333/71 (20130101) G01N 2800/368 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421820 | Conklin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | University Of New York (Albany, New York) |
| INVENTOR(S) | Douglas S. Conklin (Niskayuna, New York); Xianhui Wang (Albany, New York); Leila Kokabee (Albany, New York) |
| ABSTRACT | Receptor protein kinases (RPTKs) transmit extracellular signals across the plasma membrane to cytosolic proteins, stimulating formation of complexes that regulate key cellular functions. Over half of the known tyrosine kinases are implicated in human cancers and are therefore highly promising drug targets. A large-scale loss-of-function analysis of tyrosine kinases using RNA interference in the clinically relevant Erb-B2 positive, BT474 breast cancer cell line showed that Bruton's tyrosine kinase (BTK), a cytosolic, non-receptor tyrosine kinase that has been extensively studied for its role in B cell development, is required, in altered form, for BT474 breast cancer survival. This alternative form contains an amino-terminal extension that is also present in tumorigenic breast cells at significantly higher levels than in normal breast cells. Thus, embodiments of the invention find application in the field of cancer therapy. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/257478 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 31/704 (20130101) A61K 31/713 (20130101) A61K 45/06 (20130101) Peptides C07K 14/705 (20130101) C07K 16/40 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1205 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) Enzymes C12Y 207/10001 (20130101) C12Y 207/10002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/57415 (20130101) G01N 2333/9121 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421945 | Gu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York); The United States of America, as Represented by the Secretary, Department of Health and Human Service (Rockville, Maryland) |
| INVENTOR(S) | Hua Gu (New York, New York); Richard Hodes (Bethesda, Maryland); Jeffrey J. Chiang (Herndon, Virginia); Ihnkyung Jang (Jupiter, Florida) |
| ABSTRACT | The invention provides an isolated, purified population of human cells comprising CD8+ T cells with reduced Cbl-b activity. The invention provides uses of such cells in methods for inducing or enhancing an anti-tumor immune response in a subject. These methods comprise: (a) providing a cell population, from a subject or from another source, which comprises CD8+ T cells, (b) reducing Cbl-b activity in the CD8+ T-cells, (c) administering the cells of step (b) to the subject. The invention provides methods for making CD8+ T cells that do not require stimulation through a co-receptor in order for the cell to become activated or proliferated in response to contact via its T cell receptor. Such methods are based upon reducing function of Cbl-b. The invention also provides methods for identifying agents which affect Cbl-b expression or activity. |
| FILED | Monday, March 19, 2018 |
| APPL NO | 15/925148 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/57 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2501/998 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/25 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 2333/9015 (20130101) G01N 2333/70514 (20130101) G01N 2333/70517 (20130101) G01N 2333/70539 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421960 | June et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Carl H. June (Merion Station, Pennsylvania); Yangbing Zhao (Cherry Hill, New Jersey) |
| ABSTRACT | The present invention relates to compositions and methods for generating RNA Chimeric Antigen Receptor (CAR) transfected T cells. The RNA-engineered T cells can be used in adoptive therapy to treat cancer. |
| FILED | Monday, September 17, 2012 |
| APPL NO | 14/342904 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) Peptides C07K 14/82 (20130101) C07K 2319/03 (20130101) C07K 2319/72 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 2799/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421965 | Cubillos-Ruiz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Juan R. Cubillos-Ruiz (New York, New York); Laurie H. Glimcher (New York, New York) |
| ABSTRACT | Described herein is a previously unknown function of XBP1 in controlling anti-tumor immunity. It is shown that inhibiting XBP1 in tumor-associated dendritic cells inhibits tumor growth and induces protective anti-tumor immune responses. |
| FILED | Tuesday, January 23, 2018 |
| APPL NO | 15/877864 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/1137 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2320/31 (20130101) Enzymes C12Y 207/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421966 | Wilton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Western Australia (Crawley, Australia) |
| ASSIGNEE(S) | The University of Western Australia (Crawley, Australia) |
| INVENTOR(S) | Stephen Donald Wilton (Applecross, Australia); Sue Fletcher (Bayswater, Australia); Graham McClorey (Bayswater, Australia) |
| ABSTRACT | An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 214. |
| FILED | Tuesday, January 22, 2019 |
| APPL NO | 16/254047 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/33 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/3233 (20130101) C12N 2310/3341 (20130101) C12N 2310/3519 (20130101) C12N 2320/30 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421978 | Moss et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Bernard Moss (Bethesda, Maryland); Linda S. Wyatt (Rockville, Maryland); Patricia L. Earl (Chevy Chase, Maryland) |
| ABSTRACT | The present invention relates to new insertion sites useful for the integration of exogenous sequences into an intergenic region (IGR) of a vaccinia virus genome, where the IGR is located between or is flanked by two adjacent open reading frames (ORFs) of the vaccinia virus genome, and where the ORFs correspond to conserved genes, and to related plasmid vectors useful to insert exogenous DNA into the genome of a vaccinia virus, and further to recombinant vaccinia viruses comprising an exogenous sequence inserted into said new insertion site as a medicine or vaccine. |
| FILED | Monday, August 24, 2015 |
| APPL NO | 14/833913 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/8636 (20130101) C12N 2710/24111 (20130101) C12N 2710/24141 (20130101) C12N 2710/24143 (20130101) C12N 2710/24152 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421980 | Doudna et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); University of Vienna (Vienna, Austria); Emmanuelle Charpentier (Braunschweig, Germany) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); University of Vienna (Vienna, Austria); Emmanuelle Charpentier (Braunschweig, Germany) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Martin Jinek (Berkeley, California); Krzysztof Chylinski (Vienna, Austria); Emmanuelle Charpentier (Braunschweig, Germany) |
| ABSTRACT | The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms. |
| FILED | Wednesday, July 11, 2018 |
| APPL NO | 16/033002 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/4684 (20180501) Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/027 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/70 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/746 (20130101) C12N 15/902 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/13 (20130101) C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2310/31 (20130101) C12N 2310/32 (20130101) C12N 2310/33 (20130101) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 301/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421991 | Blaschke-Bonkowsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BioFire Diagnostics, LLC (Salt Lake City, Utah); University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | BioFire Diagnostics, LLC (Salt Lake City, Utah); University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Anne Jeannette Blaschke-Bonkowsky (Salt Lake City, Utah); Mark Aaron Poritz (Salt Lake City, Utah) |
| ABSTRACT | Methods for typing a strain of an organism are provided, the methods comprising the steps of amplifying, in a single reaction mixture containing nucleic acid from the organism, dividing the reaction mixture into a plurality of sets of second-stage reaction wells, each set of second-stage reaction wells containing a different pair of second-stage primers, subjecting each of the second-stage reaction wells to amplification conditions to generate a plurality of second-stage amplicons, melting the second-stage amplicons to generate a melting curve for each second-stage amplicon, and identifying the strain of the organism from the melting curves. |
| FILED | Wednesday, November 11, 2015 |
| APPL NO | 14/938242 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 1/689 (20130101) C12Q 1/6848 (20130101) Original (OR) Class C12Q 2527/107 (20130101) C12Q 2537/143 (20130101) C12Q 2549/119 (20130101) C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421998 | Rand |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Arthur Rand (Santa Cruz, California) |
| ABSTRACT | Provided are polynucleotide constructs useful in a nanopore analysis using enzyme activity. The polynucleotide constructs include a strand portion of interest to be analyzed in the nanopore analysis and having a 5′ end and a 3′ end, and a folded sequence located 3′ or 5′ of and adjacent to an end of the strand portion of interest, where the folded sequence can block the activity of a processive enzyme. In some embodiments, the polynucleotide constructs further include an enzyme binding sequence located 3′ of and adjacent to an end of the folded sequence, and an enzyme displacement sequence located 5′ of the strand portion of interest. Such polynucleotide constructs further include a threading sequence located 5′ of the enzyme displacement sequence and at a 5′ terminal end of the polynucleotide construct, where the processive enzyme has a processive activity in a direction from 3′ to 5′ on the polynucleotide construct. |
| FILED | Monday, September 28, 2015 |
| APPL NO | 15/515012 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2521/513 (20130101) C12Q 2521/513 (20130101) C12Q 2523/303 (20130101) C12Q 2523/303 (20130101) C12Q 2525/119 (20130101) C12Q 2525/119 (20130101) C12Q 2527/127 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422003 | Yu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aiming Yu (Granite Bay, California) |
| ABSTRACT | Provided are compositions and methods for detecting RNase activity. |
| FILED | Wednesday, March 16, 2016 |
| APPL NO | 15/558563 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/115 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/141 (20130101) C12N 2310/3519 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) C12Q 1/6876 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/922 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422004 | Rothenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Marc E. Rothenberg (Cincinnati, Ohio); Ting Wen (Cincinnati, Ohio); Seema Aceves (San Diego, California) |
| ABSTRACT | The invention provides methods for diagnosing eosinophilic esophagitis in a patient using a biomarker based assay directed to KCNJ2/Kir2.1 and related compositions, kits, and computer program products. |
| FILED | Monday, August 10, 2015 |
| APPL NO | 15/502273 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/56 (20130101) A61K 31/58 (20130101) A61K 31/573 (20130101) A61K 31/4439 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/521 (20130101) C08K 7/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) G01N 33/6893 (20130101) G01N 2333/705 (20130101) G01N 2800/06 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/20 (20180101) G16H 10/60 (20180101) G16H 15/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422006 | Samuels et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The John Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Yardena Samuels (Potomac, Maryland); Victor Velculescu (Dayton, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland) |
| ABSTRACT | Phosphatidylinositol 3-kinases (PI3Ks) are known to be important regulators of signaling pathways. To determine whether PI3Ks are genetically altered in cancers, we analyzed the sequences of the PI3K gene family and discovered that one family member, PIK3CA, is frequently mutated in cancers of the colon and other organs. The majority of mutations clustered near two positions within the PI3K helical or kinase domains. PIK3CA represents one of the most highly mutated oncogenes yet identified in human cancers and is useful as a diagnostic and therapeutic target. |
| FILED | Friday, October 31, 2014 |
| APPL NO | 14/529351 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422786 | Loomba et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Rohit Loomba (San Diego, California); Oswald Quehenberger (San Diego, California); Aaron Armando (San Diego, California); Edward A. Dennis (La Jolla, California) |
| ABSTRACT | The present invention relates to the substantially non-invasive diagnosis of liver disease, especially to enable intervention in the progression of such disease at an early stage. This invention further relates to the use of plasma biomarkers to differentiate nonalcoholic steatohepatitis (NASH) from nonalcoholic fatty liver (NAFL) and non-nonalcoholic fatty liver disease (NAFLD), and normal controls. Specifically, the invention relates to the use of free eicosanoids and other polyunsaturated fatty acid (PUFA) metabolite levels in plasma to differentiate NASH from NAFL and non-NAFLD normal controls. |
| FILED | Tuesday, December 09, 2014 |
| APPL NO | 15/100621 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/7233 (20130101) G01N 33/88 (20130101) G01N 33/92 (20130101) G01N 33/487 (20130101) Original (OR) Class G01N 2800/085 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) Technologies for Adaptation to Climate Change Y02A 90/24 (20180101) Y02A 90/26 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422787 | Lindsay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS on behalf of ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Stuart Lindsay (Phoenix, Arizona); Peiming Zhang (Gilbert, Arizona); Yanan Zhao (Tempe, Arizona) |
| ABSTRACT | A single molecule sensing or detecting device includes a first electrode and a second electrode separated from the first electrode by a gap. The first electrode and the second electrode have an opening formed therethrough. At least one of the first electrode and the second electrode is functionalized with a recognition molecule. The recognition molecule has an effective length L1 and is configured to selectively bind to a target molecule having an effective length L2. The size of the gap is configured to be greater than 2L1, but less than or equal to the sum of 2L1 and L2. |
| FILED | Monday, October 30, 2017 |
| APPL NO | 15/797052 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44791 (20130101) G01N 33/48721 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422803 | Deisseroth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Karl Deisseroth (Stanford, California); Edward S. Boyden (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides compositions and methods for light-activated cation channel proteins and their uses within cell membranes and subcellular regions. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-activated cation channels to specific cells or defined cell populations. In particular the invention provides millisecond-timescale temporal control of cation channels using moderate light intensities in cells, cell lines, transgenic animals, and humans. The invention provides for optically generating electrical spikes in nerve cells and other excitable cells useful for driving neuronal networks, drug screening, and therapy. |
| FILED | Wednesday, March 02, 2016 |
| APPL NO | 15/059159 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2217/05 (20130101) A01K 2227/40 (20130101) A01K 2227/105 (20130101) A01K 2227/703 (20130101) A01K 2227/706 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/18 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 31/353 (20130101) A61K 31/405 (20130101) A61K 31/4172 (20130101) A61K 35/30 (20130101) A61K 35/30 (20130101) A61K 38/00 (20130101) A61K 48/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3604 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0601 (20130101) A61N 5/0622 (20130101) Peptides C07K 14/405 (20130101) C07K 14/705 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/15043 (20130101) C12N 2740/15071 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) Original (OR) Class G01N 2500/04 (20130101) G01N 2500/10 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 530/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422841 | Garwood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Michael Garwood (Minneapolis, Minnesota); Woo Ju Albert Jang (Minneapolis, Minnesota) |
| ABSTRACT | Described here are systems and methods for designing and implementing spatially selective, multidimensional adiabatic radio frequency (“RF”) pulses for use in magnetic resonance imaging (“MRI”). Spatially selective inversion can be achieved adiabatically in both two-dimensional (“2D”) and three-dimensional (“3D”) regions-of-interest. The multidimensional adiabatic pulses are generally designed using sub-pulses that are adiabatically driven using a parent adiabatic pulse. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 15/493959 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4616 (20130101) G01R 33/4836 (20130101) Original (OR) Class G01R 33/5602 (20130101) G01R 33/5659 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10423123 | Brooker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CELLOPTIC, INC. (Rockville, Maryland) |
| ASSIGNEE(S) | CellOptic, Inc. (Rockville, Maryland) |
| INVENTOR(S) | Gary Brooker (Rockville, Maryland); Nisan Siegel (Silver Spring, Maryland) |
| ABSTRACT | The inventors have discovered a method to improve image quality in holography and, for the first time, utilize lenses made from birefringent materials to advantageously split an incoming beam of either coherent or incoherent light into two coincident beams with different focal lengths that interfere with one another and thus create holograms free of electro-optical or pixelated devices. This discovery has many advantages over current methods to create holograms in which many components, including multiple lenses, other electro-optical devices, and/or beam paths are necessary to create holograms. The current invention provides a purely optical holographic process which has better performance and holographic simplicity, in addition to being able to miniaturize holographic processes more than is currently possible in state of the art holography systems. |
| FILED | Thursday, April 30, 2015 |
| APPL NO | 15/308208 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/08 (20130101) G02B 5/3016 (20130101) G02B 5/3083 (20130101) G02B 27/283 (20130101) Holographic Processes or Apparatus G03H 1/06 (20130101) G03H 1/041 (20130101) Original (OR) Class G03H 1/0443 (20130101) G03H 2001/005 (20130101) G03H 2001/0216 (20130101) G03H 2001/0447 (20130101) G03H 2001/0452 (20130101) G03H 2222/31 (20130101) G03H 2223/17 (20130101) G03H 2223/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10423757 | Kruecker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jochen Kruecker (Washington, District of Columbia); Sandeep Dalal (Cortlandt Manor, New York); Bradford Johns Wood (Potomac, Maryland); Sheng Xu (Rockville, Maryland) |
| ASSIGNEE(S) | KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands) |
| INVENTOR(S) | Jochen Kruecker (Washington, District of Columbia); Sandeep Dalal (Cortlandt Manor, New York); Bradford Johns Wood (Potomac, Maryland); Sheng Xu (Rockville, Maryland) |
| ABSTRACT | A system and method for ablation planning includes defining (502) shapes and sizes for one or more ablation volumes based on probability of treatment, and determining (510) a target volume to be treated. A procedure plan is provided (516) by determining a number and location of planned ablations within the target volume using the one or more ablation volumes. A joint probability distribution (520) is determined for at least two planned ablations in the target volume. A final configuration is visualized (530) to determine if plan objectives are met based on a probability of treatment for the target volume. |
| FILED | Monday, November 07, 2011 |
| APPL NO | 13/885714 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/148 (20130101) A61B 34/10 (20160201) A61B 90/37 (20160201) A61B 2018/00577 (20130101) A61B 2034/104 (20160201) Electric Digital Data Processing G06F 19/00 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424212 | Wexler |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Bruce E. Wexler (Hamden, Connecticut) |
| ABSTRACT | A computer-implemented method, a computer program product, and a system are provided. A plurality of multi-level cognitive exercises are provided to an individual. Each of the multi-level cognitive exercises includes at least one task to perform. The individual is requested to respond to a cognitive exercise in the plurality of cognitive exercises by performing the at least one task contained in the cognitive exercise. A response provided by the individual to the cognitive exercise is monitored. Based on the monitoring, a determination is made whether the individual performed the at least one task at a predetermined performance level, wherein the performance level is defined by the at least one task contained in the cognitive exercise. Based on the determining, the individual is requested to perform at least another task. At least one activity for the individual to perform is generated. The at least one activity is based on responses to the multi-level cognitive exercises by the individual. |
| FILED | Wednesday, September 02, 2015 |
| APPL NO | 14/843708 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/00 (20130101) Original (OR) Class G09B 7/02 (20130101) G09B 7/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424471 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Richard D. Smith (Richland, Washington); Sandilya V. B. Garimella (Richland, Washington); Yehia M. Ibrahim (Richland, Washington) |
| ABSTRACT | An apparatus includes a flexible ion conduit extending between an input end situated to receive ions and an output end to define an ion passageway having an axis, the flexible ion conduit including an inner conduit portion having an inner surface facing the interior ion passageway and having a plurality of RF electrodes adjacently situated to receive RF voltages that are out of phase with respect to each other to direct the received ions away from the inner surface and into the ion passageway. |
| FILED | Tuesday, June 26, 2018 |
| APPL NO | 16/019397 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/062 (20130101) Original (OR) Class H01J 49/142 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10425106 | Halbawi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Wael Halbawi (Pasadena, California); Babak Hassibi (San Marino, California); Zihan Liu (Berkeley, California) |
| ABSTRACT | Balanced Reed-Solomon codes in accordance with embodiments of the invention enable balanced load in distributed storage systems. One embodiment includes a storage controller, wherein the storage processor is configured by the controller Reed-Solomon application to: receive a data segment; partition the data segment into a first block of data and a second block of data; transmit the first block of data to a first node controller in the plurality of node controllers; transmit the second block of data to a second node controller in the plurality of node controllers; wherein the node processor in the first node controller is configured by the node Reed-Solomon application to: receive the first block of data; encode the first block of data using a balanced and sparsest error-correcting code; and store the encoded first block of data in the node memory of the first node controller. |
| FILED | Tuesday, November 28, 2017 |
| APPL NO | 15/824948 |
| ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1044 (20130101) G06F 11/1076 (20130101) G06F 2211/1028 (20130101) G06F 2211/1057 (20130101) Coding; Decoding; Code Conversion in General H03M 13/1515 (20130101) Original (OR) Class H03M 13/3761 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10425348 | Keller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| INVENTOR(S) | Eric Keller (Louisville, Colorado); Blake Caldwell (Boulder, Colorado); Murad Kablan (Boulder, Colorado) |
| ABSTRACT | Systems and methods are described for stateless network function virtualization. Embodiments operate in context of a data network, in which network middleboxes are virtualized, for example, for added scalability and fault tolerance. The virtualized middleboxes can implement state-reliant network functions in a manner that decouples the state from the packet processing pipeline, while maintaining reliability and throughput even at very high data rates. Various embodiments include novel packet processing pipeline architectures, novel thread coordination structures (e.g., including batching and buffer pool sub-structures), novel remote state data store structures, and/or other novel features. |
| FILED | Tuesday, July 26, 2016 |
| APPL NO | 15/220129 |
| ART UNIT | 2458 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4843 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 47/621 (20130101) Original (OR) Class H04L 49/901 (20130101) H04L 67/2876 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10420345 | Clapsaddle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TDA Research, Inc (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
| INVENTOR(S) | Brady Clapsaddle (Littleton, Colorado); Joe Fredrickson (Denver, Colorado); William Bell (Boulder, Colorado); Trevor Haanstad (Denver, Colorado); Jeff Martin (Arvada, Colorado) |
| ABSTRACT | The present invention provides a humidity tolerant CO2 generator that operates in combination with an arthropod trap. The CO2 generator comprises a means for controllably adding solid pellets to an aqueous acid solution, and optionally includes a sound-based counting system for counting the number of pellets dispensed from a feeder reservoir and into a reaction chamber. The invention also provides a method of using the same. |
| FILED | Tuesday, November 07, 2017 |
| APPL NO | 15/805850 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/10 (20130101) A01M 1/023 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 59/04 (20130101) Original (OR) Class Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 83/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420346 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University Of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University Of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Peng Zhang (Cincinnati, Ohio); Niranga Wijesiri (Cincinnati, Ohio); Hong Tang (Cincinnati, Ohio) |
| ABSTRACT | The present invention relates generally to compositions and methods of killing fungi using a surface plasmon coupled to a photosensitizer. A nanostructure (10) may include a silver nanoparticle core (12), a mesoporous silica shell (14), and a photosensitizer (16). A method of killing fungi may include contacting fungi with a nanostructure (10) including a silver nanoparticle core (12), a mesoporous silica shell (14), and a photosensitizer (16) to form a blend and exposing the blend to light. |
| FILED | Monday, June 18, 2018 |
| APPL NO | 16/011154 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/26 (20130101) A01N 25/28 (20130101) A01N 25/28 (20130101) A01N 43/34 (20130101) A01N 43/713 (20130101) A01N 43/713 (20130101) A01N 59/16 (20130101) Original (OR) Class A01N 59/16 (20130101) A01N 59/16 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 41/0057 (20130101) A61K 41/0071 (20130101) A61K 47/6923 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 5/006 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/01 (20130101) C01P 2004/64 (20130101) Heterocyclic Compounds C07D 487/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420471 | Alfano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Robert R. Alfano (Bronx, New York); Yang Pu (New York, New York); Lingyan Shi (New York, New York); Sebastião Pratavieira (São Paulo, Brazil) |
| ABSTRACT | A method is provided for deep tissue imaging using multi-photon excitation of a fluorescent agent. The fluorescent agent is irradiated with an ultrafast laser to produce an excited singlet state (Sn) which subsequently undergoes non-radiative relaxation to a first singlet state (S1). The S1 state undergoes fluorescence to the ground state S0 to produce an emission wavelength. Both the excitation and emission wavelengths are within the near infrared optical window, thereby permitting deep tissue penetration for both the incoming and outgoing signals. |
| FILED | Monday, June 09, 2014 |
| APPL NO | 14/299564 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00 (20130101) A61B 5/00 (20130101) A61B 5/0059 (20130101) A61B 5/0071 (20130101) Original (OR) Class A61B 5/0082 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/001 (20130101) A61K 49/0013 (20130101) A61K 49/0019 (20130101) A61K 49/0021 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) G01N 21/17 (20130101) G01N 21/62 (20130101) G01N 21/63 (20130101) G01N 21/6486 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420659 | Marshall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Healionics Corporation (Seattle, Washington) |
| ASSIGNEE(S) | HEALIONICS CORPORATION (Seattle, Washington) |
| INVENTOR(S) | Andrew J. Marshall (Seattle, Washington); Brandt Scanlan (Seattle, Washington); Max Maginness (Seattle, Washington); Adrienne Oda (Seattle, Washington); Michael J. Connolly (Seattle, Washington); Chad MacDonald (Seattle, Washington) |
| ABSTRACT | Provided herein are implantable devices, such as vascular grafts and access port for hemodialysis, that include a microporous sheath layer having a corrugated outer surface, and use therefore for reducing the risk of infection or stenosis. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/687404 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/06 (20130101) A61F 2/064 (20130101) A61F 2/0077 (20130101) A61F 2/91 (20130101) Original (OR) Class A61F 2/848 (20130101) A61F 2210/0076 (20130101) A61F 2220/0008 (20130101) A61F 2230/0069 (20130101) A61F 2250/0024 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3653 (20130101) A61M 1/3655 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420753 | Androphy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Elliot J. Androphy (Indianapolis, Indiana); Kevin Hodgetts (Framingham, Massachusetts); Alyssa Nicole Calder (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed herein are compositions and methods for treatment of spinal muscular atrophy (SMA). In certain embodiments, compounds are provided that increase full-length survival of motor neuron (SMN) protein production by an SMN2 gene. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/862751 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2227/105 (20130101) A01K 2267/0318 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/422 (20130101) A61K 31/422 (20130101) A61K 31/426 (20130101) A61K 31/426 (20130101) A61K 31/427 (20130101) A61K 31/427 (20130101) A61K 31/437 (20130101) Original (OR) Class A61K 31/437 (20130101) A61K 31/444 (20130101) A61K 31/501 (20130101) A61K 31/501 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 31/4418 (20130101) A61K 31/4418 (20130101) A61K 31/4704 (20130101) A61K 31/4704 (20130101) A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 31/7125 (20130101) A61K 31/7125 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420819 | Soliman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| ASSIGNEE(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| INVENTOR(S) | Tarik Soliman (Cambridge, Massachusetts); Laura M. Hales (Cambridge, Massachusetts); Daniel B. Hall (Easton, Massachusetts); Howard Sard (Arlington, Massachusetts); Vishnumurthy Hegde (Chelmsford, Massachusetts) |
| ABSTRACT | The invention provides non-hormonal vitamin D conjugated to insulin peptides that result in the peptides having increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. The vitamin D targeting groups are coupled to the insulin peptides via the third carbon on the vitamin D backbone. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/468083 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/28 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/64 (20170801) A61K 47/551 (20170801) Peptides C07K 14/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420824 | Spencer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | David Spencer (Houston, Texas); Brent Hanks (Durham, North Carolina); Kevin Slawin (Houston, Texas) |
| ABSTRACT | The present invention is directed to a composition and method which to treat diseases and to enhance a regulated immune response. More particularly, the present invention is drawn to compositions that are based on dendritic cells modified to express an inducible form of a co-stimulatory polypeptide. |
| FILED | Thursday, January 05, 2017 |
| APPL NO | 15/399512 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 38/177 (20130101) A61K 38/1774 (20130101) A61K 39/02 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 2039/53 (20130101) A61K 2039/5154 (20130101) A61K 2039/5156 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/70578 (20130101) C07K 2319/033 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/10 (20130101) C12N 5/16 (20130101) C12N 9/90 (20130101) C12N 9/485 (20130101) C12N 2710/10043 (20130101) Enzymes C12Y 304/17021 (20130101) C12Y 502/01 (20130101) C12Y 502/01008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420840 | Hickey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RLL, LLC (Lutherville, Maryland) |
| ASSIGNEE(S) | RLL, LLC (Lutherville, Maryland) |
| INVENTOR(S) | Robert J. Hickey (Lakeview Terrace, California); Linda H. Malkas (Lakeview Terrace, California) |
| ABSTRACT | The invention described herein pertains to anticancer therapeutic agents that exhibit preferential cytotoxicity to malignant cells that express a cancer specific isoform of proliferating cell nuclear antigen (caPCNA) compared to cytotoxicity to comparable non-malignant cells, pharmaceutical compositions comprising the agents, and their use in cancer therapy. |
| FILED | Friday, April 10, 2015 |
| APPL NO | 14/684259 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 45/06 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421695 | Jain et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NEI Corporation (Somerset, New Jersey) |
| ASSIGNEE(S) | NEI Corporation (Somerset, New Jersey) |
| INVENTOR(S) | Mohit Jain (East Brunswick, New Jersey); Biju Mathew (Monroe, New Jersey) |
| ABSTRACT | A new class of energetic nanoparticles, and a method to produce the same. The energetic nanoparticles are differentiated from other metallic energetic nanoparticles by their core-shell nanostructure including an intermediate boride layer that provides oxidation protection and acts as an active mass. An intermetallic reaction occurs between aluminum and nickel. Aluminum based nanoparticles were used for the examples, but the principle is applicable to other materials as well. |
| FILED | Monday, July 20, 2015 |
| APPL NO | 14/803673 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0004 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 27/00 (20130101) C06B 45/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421820 | Conklin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | University Of New York (Albany, New York) |
| INVENTOR(S) | Douglas S. Conklin (Niskayuna, New York); Xianhui Wang (Albany, New York); Leila Kokabee (Albany, New York) |
| ABSTRACT | Receptor protein kinases (RPTKs) transmit extracellular signals across the plasma membrane to cytosolic proteins, stimulating formation of complexes that regulate key cellular functions. Over half of the known tyrosine kinases are implicated in human cancers and are therefore highly promising drug targets. A large-scale loss-of-function analysis of tyrosine kinases using RNA interference in the clinically relevant Erb-B2 positive, BT474 breast cancer cell line showed that Bruton's tyrosine kinase (BTK), a cytosolic, non-receptor tyrosine kinase that has been extensively studied for its role in B cell development, is required, in altered form, for BT474 breast cancer survival. This alternative form contains an amino-terminal extension that is also present in tumorigenic breast cells at significantly higher levels than in normal breast cells. Thus, embodiments of the invention find application in the field of cancer therapy. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/257478 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 31/704 (20130101) A61K 31/713 (20130101) A61K 45/06 (20130101) Peptides C07K 14/705 (20130101) C07K 16/40 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1205 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) Enzymes C12Y 207/10001 (20130101) C12Y 207/10002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/57415 (20130101) G01N 2333/9121 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421882 | Tsang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America as Represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph W. Tsang (Ridgecrest, California) |
| ABSTRACT | An epoxy-polysiloxane prepolymer composition(s) including, a mixture of polysiloxane oligomers having at least two epoxy groups, at least one monofunctional epoxy-siloxane as a reactive diluents, at least one amine, at least one pigment and/or at least one filler, at least one pigment dispersing agent, and at least one defoamer. |
| FILED | Thursday, August 11, 2016 |
| APPL NO | 15/234353 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) B05D 1/28 (20130101) B05D 3/007 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 183/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421952 | Harvey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army Edgewood Chemical Biological Center (APG, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Steven P Harvey (Lutherville, Maryland); Mark A Guelta (White Marsh, Maryland) |
| ABSTRACT | The invention is directed toward mutant, non-wild-type organophosphorus acid anhydrolases (OPPAs) having three or more site mutations, methods of production, kits and methods of use to effectively degrade toxic V-agent type chemical compounds such as VX, VR, CVX, and VM. |
| FILED | Tuesday, January 30, 2018 |
| APPL NO | 15/883331 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/02 (20130101) A62D 2101/02 (20130101) A62D 2101/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/08002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422048 | Hatchett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION on behalf of THE UNIVERSITY OF NEVADA (Las Vegas, Nevada); REACTIVE INNOVATIONS, LLC (Westford, Massachusetts) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (Las Vegas, Nevada); REACTIVE INNOVATIONS, LLC (Westford, Massachusetts) |
| INVENTOR(S) | David W. Hatchett (Las Vegas, Nevada); Kenneth R. Czerwinski (Seattle, Washington); Janelle Droessler (Las Vegas, Nevada); Karen D. Jayne (Littleton, Massachusetts); Michael C. Kimble (Westford, Massachusetts); Kyle G. Boutin (Westford, Massachusetts) |
| ABSTRACT | A process for recovering a rare earth element. The process includes adding water and a nonaqueous acid to an ionic liquid, and dissolving an oxide of a first rare earth element directly into the ionic liquid to form an ionic solution comprising at least about 0.1 weight percent water, the acid and an ion of the first rare earth element. The process further includes applying a potential to the ionic solution to deposit the first rare earth element onto an electrode as a metal. |
| FILED | Wednesday, September 30, 2015 |
| APPL NO | 15/515990 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/20 (20130101) C22B 59/00 (20130101) Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/22 (20130101) Original (OR) Class C25C 3/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422237 | McDavid |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Bruce S. McDavid (Jupiter, Florida) |
| ABSTRACT | A gas turbine engine includes a case having a wall that provides a cavity. The wall includes an aperture and a bore. A tube assembly with a flange provides a fluid passage aligned with the aperture. A flow diverter is arranged in the cavity and includes a plate with a hole. An insert has a body and a head. The body is received in the hole and press-fit in the bore. The head captures the plate against the wall. A fastener secures the flange to the insert and clamps the flow diverter to the case. |
| FILED | Tuesday, April 11, 2017 |
| APPL NO | 15/484215 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/065 (20130101) Original (OR) Class F01D 11/24 (20130101) F01D 25/12 (20130101) F01D 25/14 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 6/08 (20130101) F02C 7/18 (20130101) F02C 7/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422345 | Parker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | David Vickery Parker (Middleton, Massachusetts); Michael Macrorie (Winchester, Massachusetts); Caitlin Jeanne Smythe (Cambridge, Massachusetts); David Paul Miller (North Andover, Massachusetts) |
| ABSTRACT | A diffuser for a centrifugal compressor including an annular diffuser housing having a plurality of diffuser flow passages therethrough the housing. Each passage including a throat portion and a diffusing section with upstream and downstream diffusing portions. A diffusing passage centerline includes a linear portion extending downstream through the throat portion and the upstream diffusing portion and a curved portion of the diffusing passage centerline extending downstream from the centerline linear portion through the downstream diffusing portion. The diffuser flow passages may have an equivalent cone angle varying non-linearly or more particularly curvilinearly downstream along curved portion. The downstream diffusing portion may be flared. |
| FILED | Friday, October 17, 2014 |
| APPL NO | 15/101633 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/02 (20130101) Non-positive-displacement Pumps F04D 17/10 (20130101) F04D 29/444 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/128 (20130101) F05D 2250/324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422397 | McKnight et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Geoffrey P. McKnight (Los Angeles, California); Christopher B. Churchill (Ventura, California); Christopher P. Henry (Thousand Oaks, California) |
| ABSTRACT | A variable stiffness structure configured to isolate a mass from unwanted vibrations includes a negative stiffness element and an actuator operatively coupled to the negative stiffness element. The actuator is configured to be actuated to control a stiffness of the negative stiffness element. The variable stiffness structure may also include a positive stiffness element coupled to the negative stiffness element. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/214242 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Springs; Shock-absorbers; Means for Damping Vibration F16F 1/22 (20130101) F16F 1/26 (20130101) F16F 1/027 (20130101) Original (OR) Class F16F 1/322 (20130101) F16F 1/324 (20130101) F16F 3/00 (20130101) F16F 2224/0258 (20130101) F16F 2224/0283 (20130101) F16F 2228/063 (20130101) F16F 2228/066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422431 | Chuong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Conway Chuong (Manchester, Connecticut); Ross Wilson (South Glastonbury, Connecticut) |
| ABSTRACT | An assembly for rotational equipment includes a plurality of seal shoes, a seal base, a plurality of spring elements and a frangible element. The seal shoes are arranged around an axis in an annular array. The seal base circumscribes the annular array of the seal shoes. Each of the spring elements is radially between and connects a respective one of the seal shoes and the seal base. A first of the spring elements includes a first mount, a second mount and a spring beam. The first mount is connected to a first of the seal shoes. The second mount is connected to the seal base. The spring beam extends longitudinally between and connects the first mount and the second mount. The frangible element is configured to restrict radial outward movement of the first of the seal shoes. |
| FILED | Monday, July 17, 2017 |
| APPL NO | 15/651081 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/03 (20130101) F01D 11/14 (20130101) F01D 11/025 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/14 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/55 (20130101) Pistons; Cylinders; Sealings F16J 15/441 (20130101) F16J 15/442 (20130101) Original (OR) Class F16J 15/445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422451 | Arvelo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Amilcar R. Arvelo (Poughkeepsie, New York); Michael J. Ellsworth, Jr. (Poughkeepsie, New York); Eric J. McKeever (Poughkeepsie, New York) |
| ABSTRACT | Tapering couplers and coupling methods for connecting fluid flow components are provided. In one embodiment, the tapering coupler includes a housing with a first opening and a second opening in fluid communication through the housing. The first opening is sized for a first fluid flow component to couple to the housing, and the second opening for a second fluid flow component. The first and second fluid flow components include first and second fluid-carrying channels of different diameter, with the first fluid-carrying channel having a first channel diameter that is larger than the second channel diameter of the second fluid-carrying channel. A tapering element is associated with the housing and extends into the first fluid-carrying channel. The tapering element includes a tapering fluid-carrying channel which tapers in a direction back towards the housing, for instance, from about the first channel diameter to about the second channel diameter. |
| FILED | Wednesday, September 10, 2014 |
| APPL NO | 14/482147 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/00 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 21/002 (20130101) Original (OR) Class F16L 25/14 (20130101) F16L 55/027 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20272 (20130101) H05K 7/20772 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422613 | Reuther et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | James J. Reuther (Worthington, Ohio); Paul E. Shawcross (Hilliard, Ohio); Chad M. Cucksey (Worthington, Ohio); Ronald L. Loeser (Bexley, Ohio); John R. Leach (Tucson, Arizona); Jason E. Paugh (Columbus, Ohio); Emmett Mark Tackett (West Jefferson, Ohio); James D. Gombarcik (Richwood, Ohio) |
| ABSTRACT | A self-glowing solid material comprises a man-made metal mixture containing at least one rare earth metal and an oxide of iron. The material is inducible by flame initiation to self-glow with yellow-to-red colors (577-to-700 nanometer wavelengths). A stealth tracer ammunition comprises a projectile body having a tip and a base, and a solid pellet disposed in the base. The pellet may be made from the above-mentioned self-glowing solid material or another suitable material. The pellet becomes incandescent as a result of being heated when the ammunition is fired. The incandescent pellet emits a glow observable only from behind when the ammunition travels downrange after being fired. An illuminant comprises a bimodal blend of a man-made metal mixture containing at least one rare earth metal and an oxide of iron. The bimodal blend is a blend of smaller-sized fragments and larger-sized pellets. The illuminant is capable of ignition and dispersion in response to ballistic energy to create illumination. An illumination device comprises a body having an interior cavity, the body configured to be launched as a projectile or configured to contain projectiles. An illuminant is disposed in the cavity, the illuminant comprising a bimodal blend of a suitable illuminant material. The illuminant is capable of ignition and dispersion in response to ballistic energy to create illumination. |
| FILED | Thursday, December 01, 2016 |
| APPL NO | 15/366323 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 23/008 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 7/02 (20130101) F42B 12/38 (20130101) Original (OR) Class F42B 12/42 (20130101) F42B 12/382 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422644 | Clymer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Richard E. Clymer (Concord, New Hampshire); Jeffrey A. Paul (Milford, New Hampshire); Dean C. Slocum (Nashua, New Hampshire) |
| ABSTRACT | A method for improving target location accuracy in direction finding systems is disclosed. A target search region is identified based on a set of received signals, and the target search region is projected onto the earth's surface. An initial search grid, which is smaller than the target search region, is placed within the target search region. Next, the initial search grid is expanded to a full search grid by using an optimum number of virtual grid points in order to cover the entire target search region. The correlation coefficients at the virtual grid points between the estimated phases of emitted signals and the estimated phases of the received signals are then calculated. A target is designated as being at a location associated with the highest correlation coefficient. At this point, a new travel path can be initiated to engage or avoid the target. |
| FILED | Thursday, November 09, 2017 |
| APPL NO | 15/808246 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/20 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0252 (20130101) G01S 5/0268 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422699 | Vella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Jarrett H. Vella (New Carlisle, Ohio); Joshua Hendrickson (Dayton, Ohio); Justin W. Cleary (Miamisburg, Ohio); Shivashankar R. Vangala (Mason, Ohio) |
| ABSTRACT | A hybrid plasmonic-pyroelectric detector and laser detection system is disclosed. The hybrid plasmonic-pyroelectric detector includes a substrate and a refractory ground plane mounted on a surface of the substrate. A plasmonic array defines a plurality of apertures formed in the array. A highly-oriented pyroelectric layer is mounted on a surface of the ground plane and a surface of the plasmonic array. The plasmonic array is constructed and arranged to select particular wavelengths. Alternatively, a semiconductor or an avalanche material may be used. A pair of electrode contacts are coupled to each of the plasmonic array and the refractory ground plane. A laser detection system in accordance with the disclosure includes a mechanical chopper, a lens, a folding mirror, and a chip carrier for mounting the hybrid plasmonic-pyroelectric detector. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/106368 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/34 (20130101) Original (OR) Class G01J 5/046 (20130101) G01J 5/061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422764 | Gupta |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
| INVENTOR(S) | Chaitanya Gupta (Foster City, California) |
| ABSTRACT | A system for determining chemistry of a molecule in a high background interfering liquid environment by application of an electronic signal at a biased metal-electrolyte interface is disclosed. One or more of a resonant exchange of energy between one or more electrons exchanged by the metal and the electrolyte and vibrating bonds of a molecular analyte, for example, may be sensed by measuring small signal conductivity of an electrochemical interface. |
| FILED | Tuesday, February 02, 2016 |
| APPL NO | 15/013384 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/301 (20130101) G01N 27/327 (20130101) Original (OR) Class G01N 27/4145 (20130101) G01N 27/4148 (20130101) G01N 33/561 (20130101) G01N 33/6803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422947 | Aizenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); University of Exeter (Exeter, United Kingdom) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); University of Exeter (Exeter, United Kingdom) |
| INVENTOR(S) | Joanna Aizenberg (Boston, Massachusetts); Mathias Kolle (Hull, Massachusetts); Peter Vukusic (Exeter, United Kingdom); Robert D. Howe (Cambridge, Massachusetts) |
| ABSTRACT | The rolled photonic fibers presents two codependent, technologically exploitable features for light and color manipulation: regularity on the nanoscale that is superposed with microscale cylindrical symmetry, resulting in wavelength selective scattering of light in a wide range of directions. The bio-inspired photonic fibers combine the spectral filtering capabilities and color brilliance of a planar Bragg stack compounded with a large angular scattering range introduced by the microscale curvature, which also decreases the strong directional chromaticity variation usually associated with flat multilayer reflectors. Transparent and elastic synthetic materials equip the multilayer interference fibers with high reflectance that is dynamically tuned by longitudinal mechanical strain. A two-fold elongation of the elastic fibers results in a shift of reflection peak center wavelength of over 200 nm. |
| FILED | Friday, October 19, 2018 |
| APPL NO | 16/165490 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/242 (20130101) G01L 1/247 (20130101) Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) G02B 6/023 (20130101) G02B 6/0239 (20130101) Original (OR) Class G02B 6/0285 (20130101) G02B 6/02033 (20130101) G02B 6/02038 (20130101) G02B 6/02304 (20130101) G02B 6/02309 (20130101) G02B 6/03611 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10423129 | Huynh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Vu Anh Huynh (Canbridge, Massachusetts); Emilio Frazzoli (Cambridge, Massachusetts) |
| ABSTRACT | A computer-based method controls a dynamical system in an uncertain environment within a bounded probability of failure. The dynamical system has a state space and a control space. The method includes diffusing a risk constraint corresponding to the bounded probability of failure into a martingale that represents a level of risk tolerance associated with the dynamical system over time. The state space and the control space of the dynamical system are augmented with the martingale to create an augmented model with an augmented state space and an augmented control space. The method may include iteratively constructing one or more Markov Decision Processes (MDPs), with each iterative MDP represents an incrementally refined model of the dynamical system. The method further includes computing a first solution based on the augmented model or, if additional time was available, based on one of the MDP iterations. |
| FILED | Wednesday, July 26, 2017 |
| APPL NO | 15/660146 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/04 (20130101) Original (OR) Class G05B 23/0248 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10423171 | Streeter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| ASSIGNEE(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| INVENTOR(S) | Alexander D. Streeter (Concord, New Hampshire); David E. Altobelli (Hollis, New Hampshire); N. Christopher Perry (Manchester, New Hampshire) |
| ABSTRACT | A control unit system. The system includes a control unit which includes a control unit charging interface, at least one magnet located proximate to the control unit charging interface, at least one actuator, a detachable manifold including at least one magnet, fluidly coupled to the at least one actuator, a pump connected to the at least one actuator for causing actuation thereof, and a control system for controlling the pump, wherein the control system controls the pump to actuate the at least one actuator at least in response to a signal received by the control system. The system also includes a recharging device configured to receive the control unit, the recharging device including a reed switch, wherein when the magnet in the control unit is located proximate to the reed switch, the switch is activated. |
| FILED | Monday, September 29, 2014 |
| APPL NO | 14/499823 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/68 (20130101) A61F 2/7843 (20130101) A61F 5/012 (20130101) A61F 5/024 (20130101) A61F 5/34 (20130101) A61F 2002/704 (20130101) A61F 2002/741 (20130101) A61F 2002/745 (20130101) A61F 2002/5083 (20130101) A61F 2002/7635 (20130101) A61F 2002/7655 (20130101) A61F 2007/006 (20130101) A61F 2007/0063 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 39/00 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 7/0623 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10423633 | Mirhaji |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Parsa Mirhaji (Pearland, Texas) |
| ABSTRACT | Embodiments of methods and systems for informatics systems are disclosed. Such informatics systems may utilize a unifying format to represent text to facilitate linking between data from the text and one or more ontologies, and the commensurate ability to mine such data. |
| FILED | Wednesday, October 26, 2016 |
| APPL NO | 15/335205 |
| ART UNIT | 2165 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/22 (20190101) G06F 16/248 (20190101) G06F 16/367 (20190101) G06F 16/2465 (20190101) Original (OR) Class G06F 16/3329 (20190101) G06F 16/3344 (20190101) G06F 16/9024 (20190101) G06F 17/271 (20130101) G06F 17/274 (20130101) G06F 17/277 (20130101) G06F 17/2775 (20130101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10423735 | Chainer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Timothy Joseph Chainer (Putnam Valley, New York); Pritish Ranjan Parida (Fishkill, New York) |
| ABSTRACT | Techniques that facilitate hybrid modeling for a device under test associated with a cooling system (e.g., a two-phase cooling system) are provided. In one example, information indicative of a first model of a device under test associated with a cooling system is determined. Second information indicative of constraints that define values for an operational quantity related to the cooling system is also determined. Information indicative of a second model for the device under test is generated based on the information indicative of the first model and the second information indicative of the one or more constraints. In an aspect, a first simulation process is performed to determine first thermal properties for a first simulation domain associated with the device under test. In another aspect, a second simulation process is performed to determine second thermal properties for a second simulation domain associated with the device under test. |
| FILED | Wednesday, June 29, 2016 |
| APPL NO | 15/196713 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/30 (20180101) F24F 11/52 (20180101) Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class G06F 2217/40 (20130101) G06F 2217/78 (20130101) G06F 2217/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424071 | Menozzi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
| INVENTOR(S) | Alberico Menozzi (Raleigh, North Carolina) |
| ABSTRACT | The described technology regards an augmented reality system and method for estimating a position of a location of interest relative to the position and orientation of a display based upon a retroactive adjustment of a previously rendered position and orientation of the display, by means of an adjust-update-predict (AUP) cycle, and calculating the location of interest relative to the position and orientation of the display. Systems of the described technology include including a plurality of sensors, a processing module or other computation means, and a database. Methods of the described technology use data from the sensor package useful to accurately render graphical user interface information on a display. |
| FILED | Thursday, September 14, 2017 |
| APPL NO | 15/704986 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/165 (20130101) Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) G02B 27/0093 (20130101) G02B 2027/0138 (20130101) G02B 2027/0141 (20130101) G02B 2027/0181 (20130101) Electric Digital Data Processing G06F 1/163 (20130101) G06F 3/01 (20130101) G06F 3/011 (20130101) G06F 3/04817 (20130101) G06F 11/00 (20130101) Image Data Processing or Generation, in General G06T 5/20 (20130101) G06T 7/33 (20170101) Original (OR) Class G06T 11/00 (20130101) G06T 19/006 (20130101) G06T 2200/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424284 | Morozov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Teledyne Instruments, Inc. (Thousand Oaks, California) |
| ASSIGNEE(S) | TELEDYNE INSTRUMENTS, INC. (Thousand Oaks, California) |
| INVENTOR(S) | Andrey K. Morozov (N. Falmouth, Massachusetts) |
| ABSTRACT | An underwater sound source includes an acoustical driver, a controller of the acoustical driver, and a resonant tube acoustically coupled to the acoustical driver. The resonant tube has a pair of slotted portions, in which each slotted portion is disposed along the length of the resonant tube at a location corresponding to a node of a harmonic of the resonant tube. The sound system is configured to emit an output signal within a bandwidth defined by a dual resonance characteristic of the resonator tube. The sound source may also include a pair of coaxial tubular sleeves disposed around the resonant tube, each sleeve configured to slidably cover one of the slotted portions, and tune the resonance frequency of the tube over a wide range. At a high frequency end, when slots are uncovered, the frequency response of the resonant tube obtains a dual-resonant form. |
| FILED | Friday, April 13, 2018 |
| APPL NO | 15/952334 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/20 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/02 (20130101) G01V 1/133 (20130101) G01V 1/137 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 9/08 (20130101) Original (OR) Class G10K 11/04 (20130101) G10K 11/172 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/44 (20130101) H04R 1/345 (20130101) H04R 1/2857 (20130101) H04R 3/04 (20130101) H04R 17/00 (20130101) Technologies for Adaptation to Climate Change Y02A 90/36 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424341 | Thornton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jason R. Thornton (Chelmsford, Massachusetts); Christine M. Russ (Stoneham, Massachusetts); Nicholas Gallo (Irvine, California) |
| ABSTRACT | Cyclical pixel-based remapping techniques are disclosed for efficiently creating and displaying a video summary. Cyclical temporal remapping at the pixel level requires less processing power and eliminates the need for object identification and tracking, allowing for dynamic adjustment of summary video parameters while a user is viewing the summary video. An operator can select an archived camera feeds or video file, specify a time compression ratio or time interval over which to review video content, specify a motion sensitivity threshold, and then view a significantly condensed summary video that depicts all activity from the source video within a much shorter timeline. Furthermore, activity co-occurrence is preserved such that any activities that co-occur in the source video will also co-occur in the summary video. |
| FILED | Wednesday, November 12, 2014 |
| APPL NO | 14/539672 |
| ART UNIT | 2484 — Recording and Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04845 (20130101) G06F 3/04847 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 13/19602 (20130101) G08B 13/19682 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 27/06 (20130101) Original (OR) Class G11B 27/3081 (20130101) Pictorial Communication, e.g Television H04N 7/18 (20130101) H04N 7/181 (20130101) H04N 21/8549 (20130101) H04N 21/44008 (20130101) H04N 21/47217 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424612 | Forrest et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Stephen R. Forrest (Ewing, New Jersey); Xin Xu (Ewing, New Jersey); Christopher Kyle Renshaw (Ewing, New Jersey) |
| ABSTRACT | A method of forming a semiconductor device includes the steps of providing a first circuit layer including a plurality of first contacts, providing one or more semiconductor devices disposed on a stamp, the one or more semiconductor devices including a plurality of second contacts, bonding the plurality of second contacts to the plurality of first contacts via a pressure applied by the stamp. |
| FILED | Monday, June 13, 2016 |
| APPL NO | 15/180537 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/307 (20130101) H01L 27/3253 (20130101) H01L 27/14609 (20130101) H01L 27/14612 (20130101) H01L 27/14692 (20130101) Original (OR) Class H01L 51/0021 (20130101) H01L 51/0022 (20130101) H01L 51/0097 (20130101) H01L 2251/5338 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 13/046 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4913 (20150115) Y10T 29/49128 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424643 | Hobart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Karl D. Hobart (Alexandria, Virginia); Andrew D. Koehler (Alexandria, Virginia); Francis J. Kub (Arnold, Maryland); Travis J. Anderson (Alexandria, Virginia); Tatyana I. Feygelson (Springfield, Virginia); Marko J. Tadjer (Springfield, Virginia); Lunet E. Luna (Wheaton, Maryland) |
| ABSTRACT | A device structure and method for improving thermal management in highly scaled, high power electronic and optoelectronic devices such as GaN FET and AlGaN/GaN HEMT devices by implementing diamond air bridges into such devices to remove waste heat. The diamond air bridge can be formed from a polycrystalline diamond material layer which can be grown on the surface of a dielectric material layer, on the surface of a III-nitride material, or on the surface of a diamond polycrystalline nucleation layer, and may be optimized to have a high thermal conductivity at the growth interface with the underlying material. |
| FILED | Tuesday, April 23, 2019 |
| APPL NO | 16/391342 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/45 (20130101) H01L 29/1602 (20130101) Original (OR) Class H01L 29/4232 (20130101) H01L 29/7786 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424660 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cree, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Qingchun Zhang (Cary, North Carolina); Alexander V. Suvorov (Durham, North Carolina) |
| ABSTRACT | A power MOSFET includes a silicon carbide drift region having a first conductivity type, first and second well regions located in upper portions of the silicon carbide drift region that are doped with second conductivity dopants, and a channel region in a side portion of the first well region, an upper portion of the channel region having the first conductivity type, wherein a depth of the first well region is at least 1.5 microns and the depth of the first well region exceeds a distance between the first and second well regions. |
| FILED | Thursday, December 21, 2017 |
| APPL NO | 15/849975 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/26513 (20130101) H01L 29/086 (20130101) H01L 29/105 (20130101) H01L 29/1608 (20130101) H01L 29/7802 (20130101) Original (OR) Class H01L 29/66068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424711 | Schoelkopf, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Robert J. Schoelkopf, III (Madison, Connecticut); Teresa Brecht (New Haven, Connecticut); Luigi Frunzio (North Haven, Connecticut); Michel Devoret (New Haven, Connecticut) |
| ABSTRACT | Some embodiments are directed to a device including multiple substrates comprising one or more troughs. The substrates are disposed such that the one or more troughs form at least one enclosure. At least one superconducting layer covers at least a portion of the at least one enclosure. Other embodiments are directed to a method for manufacturing a superconducting device. The method includes acts of forming at least one trough in at least a first substrate; covering at least a portion of the first substrate with a superconducting material; covering at least a portion of a second substrate with the superconducting material; and bonding the first substrate and the second substrate to form at least one enclosure comprising the at least one trough and the superconducting material. |
| FILED | Friday, January 17, 2014 |
| APPL NO | 14/761912 |
| ART UNIT | 2896 — Semiconductors/Memory |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) H01L 39/08 (20130101) H01L 39/14 (20130101) Original (OR) Class H01L 39/24 (20130101) H01L 39/025 (20130101) H01L 39/045 (20130101) H01L 39/223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424712 | Schoelkopf, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Robert J. Schoelkopf, III (Madison, Connecticut); Luigi Frunzio (North Haven, Connecticut); Michel Devoret (New Haven, Connecticut); Teresa Brecht (New Haven, Connecticut) |
| ABSTRACT | Some embodiments are directed to a device including multiple substrates comprising one or more troughs. The substrates are disposed such that the one or more troughs form at least one enclosure. At least one superconducting layer covers at least a portion of the at least one enclosure. Other embodiments are directed to a method for manufacturing a superconducting device. The method includes acts of forming at least one trough in at least a first substrate; covering at least a portion of the first substrate with a superconducting material; covering at least a portion of a second substrate with the superconducting material; and bonding the first substrate and the second substrate to form at least one enclosure comprising the at least one trough and the superconducting material. |
| FILED | Friday, January 17, 2014 |
| APPL NO | 14/761914 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) H01L 39/02 (20130101) H01L 39/24 (20130101) Original (OR) Class H01L 39/045 (20130101) H01L 39/2406 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49016 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424836 | McMichael et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Ian T. McMichael (Stow, Massachusetts); Steven R. Best (Townsend, Massachusetts); Erik T. Lundberg (Cambridge, Massachusetts); Eddie N. Rosario (Mathuen, Massachusetts) |
| ABSTRACT | A helix antenna including a first radiating element extending helically about a longitudinal axis and tuned to resonate in a frequency band, a reactive element electrically connected to a first end of the first radiating element, and a second radiating element extending helically about the axis and electrically connected to the reactive element at a first end of the second radiating element, wherein the second radiating element is tuned to resonate in the frequency band. |
| FILED | Monday, September 26, 2016 |
| APPL NO | 15/276353 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/241 (20130101) H01Q 1/362 (20130101) Original (OR) Class H01Q 5/321 (20150115) H01Q 9/145 (20130101) H01Q 11/08 (20130101) H01Q 21/24 (20130101) H01Q 21/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10425411 | Huang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Dijiang Huang (Chandler, Arizona) |
| ABSTRACT | Systems and apparatuses for a secure mobile cloud framework (referred to as MobiCloud) for mobile computing and communication are disclosed. Embodiments of MobiCloud transfer each mobile node from a traditional strictly layer-structured communication node into a service node (SN). Each SN may be used as a service provider or a service broker according its capability. Each SN may be incorporated as a virtualized component of the MobiCloud. In some embodiments, MobiCloud mirrors an SN to one or multiple virtual images in the Cloud for addressing communication and computation deficiencies of mobile devices. Virtual images can create a visualized MANET routing and communication layer that can maximally assist the mobile nodes to enable pervasive computing services for each mobile device owner. A secure data processing framework is disclosed for the MobiCloud. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/775496 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0484 (20130101) G06F 9/5072 (20130101) G06F 9/45558 (20130101) G06F 21/335 (20130101) G06F 2009/45562 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/30 (20130101) H04L 9/3073 (20130101) H04L 9/3268 (20130101) H04L 41/0806 (20130101) H04L 47/70 (20130101) H04L 63/08 (20130101) H04L 63/0272 (20130101) H04L 63/0876 (20130101) Original (OR) Class H04L 67/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10425598 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Joseph Hsuhuan Lin (Lowell, Massachusetts); Michael Kelly (North Reading, Massachusetts); Ralph Hamilton Shepard, III (Somerville, Massachusetts); Brian Tyrrell (Brookline, New Hampshire) |
| ABSTRACT | An imaging system uses a dynamically varying coded mask, such as a spatial light modulator (SLM), to time-encode multiple degrees of freedom of a light field in parallel and a detector and processor to decode the encoded information. The encoded information may be decoded at the pixel level (e.g., with independently modulated counters in each pixel), on a read-out integrated circuit coupled to the detector, or on a circuit external to the detector. For example, the SLM, detector, and processor may create modulation sequences representing a system of linear equations where the variables represent a degree of freedom of the light field that is being sensed. If the number of equations and variables form a fully determined or overdetermined system of linear equations, the system of linear equations' solution can be determined through a matrix inverse. Otherwise, a solution can be determined with compressed sensing reconstruction techniques with the constraint that the signal is sparse in the frequency domain. |
| FILED | Tuesday, June 20, 2017 |
| APPL NO | 15/627775 |
| ART UNIT | 2422 — Cable and Television |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0229 (20130101) Optical Elements, Systems, or Apparatus G02B 26/00 (20130101) G02B 2207/129 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/1335 (20130101) G02F 1/13318 (20130101) G02F 1/133526 (20130101) G02F 1/133528 (20130101) G02F 2203/12 (20130101) Pictorial Communication, e.g Television H04N 5/332 (20130101) Original (OR) Class H04N 7/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10425622 | Brudnak |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. GOVERMENT AS REPRESENTED BY THE SECRETARY OF THE UNITED STATES ARMY (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Mark J. Brudnak (Rochester Hills, Michigan) |
| ABSTRACT | A method for generating a predictive image to enable remote control of an unmanned ground vehicle (UGV) under conditions of long communications latency. An original digital image of the UGV environment (from a UGV-mounted camera) is projected forward such that a lower portion falls on a ground plane defined to approximate the UGV's travel surface and an upper portion falls on a far plane defined approximately normal to the ground plane and forward of the UGV. A perspective transformation technique used to generate the predicted image separates the ground plane image from the far plane image. Two separate mathematical perspective transforms are defined and applied, one for the lower (ground plane) part of the image, and one for the upper (far plane) part of the image. The resulting predicted upper and lower image are rejoined to form the complete predicted image, which may then be presented on a video screen. |
| FILED | Tuesday, July 18, 2017 |
| APPL NO | 15/652975 |
| ART UNIT | 2425 — Cable and Television |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0038 (20130101) G05D 1/0044 (20130101) Image Data Processing or Generation, in General G06T 3/0012 (20130101) Pictorial Communication, e.g Television H04N 7/185 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10425708 | Kanter |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gregory S. Kanter (Chicago, Illinois) |
| ASSIGNEE(S) | Nucript LLC (Evanston, Illinois) |
| INVENTOR(S) | Gregory S. Kanter (Chicago, Illinois) |
| ABSTRACT | A method for controlling the splitting ratio of an input optical signal to one or more output ports is described. The splitting ratio of a fiber-coupled signal in the communications band is controlled using cross phase modulation from a pump signal in the 980-1090 nm band. This design allows the nonlinear fiber in which the cross phase modulation occurs to be standard single mode fiber having a zero dispersion wavelength between 1250 and 1350 nm, such as SMF-28e fiber, which helps to maintain the lowest possible loss and a low cost while still allowing for power efficient interactions with signal wavelengths in the technologically important 1520-1610 nm band. The design is compatible with low insertion loss, narrow switching windows, and low added noise. The location of the pump pulse can be controlled allowing for the location of an input pulse to be determined. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/953626 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3131 (20130101) G02F 1/3136 (20130101) G02F 2203/50 (20130101) Transmission H04B 10/70 (20130101) H04B 10/516 (20130101) H04B 10/2507 (20130101) Selecting H04Q 11/0005 (20130101) Original (OR) Class H04Q 2011/0015 (20130101) H04Q 2011/0035 (20130101) H04Q 2011/0083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10425742 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Qin Zhou (Fremont, California); Alexander Zettl (Kensington, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus associated with an electrostatically driven graphene speaker. In one aspect, a device includes a graphene membrane, a first frame on a first side of the graphene membrane, and a second frame on a second side of the graphene membrane. The first frame and the second frame both include substantially circular open regions that define a substantially circular portion of the graphene membrane. A first electrode is proximate the first side of the circular portion of the graphene membrane. A second electrode proximate the second side of the circular portion of the graphene membrane. |
| FILED | Friday, June 12, 2015 |
| APPL NO | 14/737903 |
| ART UNIT | 2651 — Videophones and Telephonic Communications |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 19/02 (20130101) H04R 19/005 (20130101) Original (OR) Class H04R 23/002 (20130101) H04R 29/001 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/733 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426023 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jinbo Li (Davis, California); Qun Gu (Davis, California) |
| ABSTRACT | The disclosed embodiments relate to the design of a system that implements a coupling balance scheme for differential signals. The system includes a set of 2N signal lines carrying N differential signal pairs, wherein the set of 2N signal lines runs parallel to each other in a planar layout. The set of 2N signal lines is organized into a set of consecutive sequences, wherein each sequence includes a pattern of twists that switch signal positions for each differential pair to cancel coupling effects with respect to other signal lines. Moreover, the positions of differential signal pairs are exchanged between consecutive sequences, so that the set of consecutive sequences includes a sequence for each possible ordering of the N differential signal pairs. |
| FILED | Wednesday, February 07, 2018 |
| APPL NO | 15/891230 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/52 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/08 (20130101) Amplifiers H03F 3/005 (20130101) H03F 3/45479 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 19/002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0228 (20130101) Original (OR) Class H05K 1/0245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10421081 | Rector |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Michael N. Rector (Tijeras, New Mexico) |
| ABSTRACT | Technologies pertaining to a centrifuge that comprises a vector-seeking linkage are disclosed herein. In a general embodiment, the centrifuge comprises a spindle that is rotatable about an axis of rotation. The centrifuge also has an arm that is coupled to the spindle, and a vector-seeking linkage that is coupled to the arm. The vector-seeking linkage provides two rotational degrees of freedom with respect to a load coupled to the vector-seeking linkage. The centrifuge is well-suited for a variety of applications, including sensor testing, solution separation, and producing accelerations expected to be experienced during flight. |
| FILED | Tuesday, June 09, 2015 |
| APPL NO | 14/735008 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Centrifuges B04B 5/0421 (20130101) B04B 9/10 (20130101) Original (OR) Class Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 25/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421709 | Leonard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Philip Leonard (Los Alamos, New Mexico); Michael Bange (Los Alamos, New Mexico) |
| ABSTRACT | Production of 2,4,6-triamino-1,3,5-trinitrobenzene (TATB) through a safer, less harmful process while yielding a superior product is disclosed. The biphasic production process may include mixing a solution of 1,3,5-trichloro-2,4,6-trinitrobenzene (TCTNB) and a surfactant into a solvent in a sealed, heated vessel such that TATB is formed in a mixture. The biphasic production process may also include pressurizing the vessel with gaseous ammonia such that aqueous TATB is formed and separating the TATB from the mixture. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 16/398612 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 209/10 (20130101) Original (OR) Class C07C 211/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421722 | Tu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhude Tu (St. Louis, Missouri); Zonghua Luo (St. Louis, Missouri); Hui Liu (St. Louis, Missouri); Hongjun Jin (St. Louis, Missouri); Stanley M. Parsons (Santa Barbara, California) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zhude Tu (St. Louis, Missouri); Zonghua Luo (St. Louis, Missouri); Hui Liu (St. Louis, Missouri); Hongjun Jin (St. Louis, Missouri); Stanley M. Parsons (Santa Barbara, California) |
| ABSTRACT | The present invention generally relates to various compounds that are useful as vesicular acetylcholine transporter (VAChT) ligands. The invention further relates to methods of using these compounds and their radiolabeled analogs for the detection of neurodegenerative diseases including Parkinson's disease (PD), and Alzheimer's disease (AD). |
| FILED | Monday, June 12, 2017 |
| APPL NO | 15/620263 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 51/0455 (20130101) A61K 51/0457 (20130101) A61K 51/0497 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) C07B 2200/05 (20130101) Heterocyclic Compounds C07D 211/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421975 | Benning et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Christoph Benning (East Lansing, Michigan); John B. Ohlrogge (Okemos, Michigan); Wei Ma (Lansing, Michigan); Que Kong (Lansing, Michigan) |
| ABSTRACT | The application describes plants, plant cells, and seeds that express WRINKLED1 transcription factors and/or 14-3-3 proteins that are useful for increasing production of oils in plants and seeds. Also described are expression systems and cassettes that encode and express such WRINKLED1 transcription factors and/or 14-3-3 proteins. |
| FILED | Monday, June 19, 2017 |
| APPL NO | 15/627006 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class C12N 15/8261 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422023 | Noack et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Clinton W. Noack (Pittsburgh, Pennsylvania); Athanasios K. Karamalidis (Pittsburgh, Pennsylvania); David A. Dzombak (Pittsburgh, Pennsylvania) |
| ABSTRACT | The disclosure describes a method of extraction for optimal recovery of rare earth elements (REE). This includes the optimization of a liquid-liquid extraction technique for economic extraction of REE from chemically complex brines. Through the use of a model, operating conditions are altered to increase separation efficiency. The technique achieves >98% recovery of all rare earth elements in one fraction, while using small volumes of sample and reagents. The method of the present invention recovers REE from previously unexploited waste streams, without need for development of new process equipment and while keeping a small footprint because of the volumes involved. |
| FILED | Monday, April 25, 2016 |
| APPL NO | 15/138117 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 11/04 (20130101) B01D 11/0488 (20130101) B01D 11/0492 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/0008 (20130101) C22B 59/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4055 (20130101) G01N 2001/4061 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/234 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422051 | Whalen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Jeffrey Whalen (Tallahassee, Florida); Theo Siegrist (Tallahassee, Florida) |
| ABSTRACT | Single crystals of the new semiconducting oxychalcogenide phase were synthesized using a novel crystal growth method. The crystals had low defects and homogeneous composition as characterized by single crystal X-ray diffraction and scanning electron microscopy, respectively. Heat capacity and resistivity measurements were in agreement with the calculated band structure calculations indicating semiconductivity, with a band gap of about 3 eV. |
| FILED | Tuesday, August 15, 2017 |
| APPL NO | 15/677706 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 9/10 (20130101) C30B 9/12 (20130101) C30B 29/22 (20130101) C30B 29/46 (20130101) Original (OR) Class Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/08 (20130101) H01B 1/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422477 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Wenping Zhao (Glastonbury, Connecticut); Andrzej Ernest Kuczek (Bristol, Connecticut); Ellen Y. Sun (South Windsor, Connecticut) |
| ABSTRACT | A composite vessel assembly includes a circumferentially continuous wall and an end cap. The wall includes a plurality of layers, and the end cap includes a plurality of steps. Each step of the plurality of steps is engaged to a respective layer of the plurality of layers. |
| FILED | Friday, April 07, 2017 |
| APPL NO | 15/481597 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/345 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/0872 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7126 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/00 (20130101) F17C 1/04 (20130101) F17C 1/06 (20130101) F17C 1/16 (20130101) Original (OR) Class F17C 13/00 (20130101) F17C 2201/054 (20130101) F17C 2201/056 (20130101) F17C 2201/0109 (20130101) F17C 2201/0166 (20130101) F17C 2201/0171 (20130101) F17C 2203/066 (20130101) F17C 2203/0604 (20130101) F17C 2203/0619 (20130101) F17C 2203/0621 (20130101) F17C 2203/0624 (20130101) F17C 2203/0636 (20130101) F17C 2203/0663 (20130101) F17C 2203/0673 (20130101) F17C 2209/225 (20130101) F17C 2209/232 (20130101) F17C 2209/234 (20130101) F17C 2209/2118 (20130101) F17C 2209/2127 (20130101) F17C 2209/2154 (20130101) F17C 2221/012 (20130101) F17C 2221/031 (20130101) F17C 2221/033 (20130101) F17C 2221/035 (20130101) F17C 2223/033 (20130101) F17C 2223/035 (20130101) F17C 2223/036 (20130101) F17C 2223/0123 (20130101) F17C 2260/01 (20130101) F17C 2260/011 (20130101) F17C 2260/018 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/321 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422481 | Tamburello et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Alken, South Carolina) |
| INVENTOR(S) | David A. Tamburello (Aiken, South Carolina); Donald L. Anton (Aiken, South Carolina); Bruce J. Hardy (Graniteville, South Carolina); Claudio Corgnale (Aiken, South Carolina) |
| ABSTRACT | In one aspect, a system for controlling the temperature within a gas adsorbent storage vessel of a vehicle may include an air conditioning system forming a continuous flow loop of heat exchange fluid that is cycled between a heated flow and a cooled flow. The system may also include at least one fluid by-pass line extending at least partially within the gas adsorbent storage vessel. The fluid by-pass line(s) may be configured to receive a by-pass flow including at least a portion of the heated flow or the cooled flow of the heat exchange fluid at one or more input locations and expel the by-pass flow back into the continuous flow loop at one or more output locations, wherein the by-pass flow is directed through the gas adsorbent storage vessel via the by-pass line(s) so as to adjust an internal temperature within the gas adsorbent storage vessel. |
| FILED | Wednesday, May 17, 2017 |
| APPL NO | 15/597336 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles B60H 1/14 (20130101) B60H 1/00271 (20130101) Internal-combustion Piston Engines; Combustion Engines in General F02B 43/12 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 21/06 (20130101) F02M 21/0221 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 11/00 (20130101) F17C 11/007 (20130101) F17C 13/005 (20130101) Original (OR) Class F17C 2227/0395 (20130101) F17C 2250/0631 (20130101) F17C 2270/0168 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 5/02 (20130101) F25B 6/02 (20130101) F25B 41/04 (20130101) F25B 2400/0403 (20130101) F25B 2400/0409 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422552 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Zhiwen Ma (Golden, Colorado); Craig S. Turchi (Lakewood, Colorado); Janna Martinek (Lafayette, Colorado); Timothy J. Wendelin (Lakewood, Colorado); Mark S. Mehos (Boulder, Colorado); Judy C. Netter (Westminster, Colorado) |
| ABSTRACT | A device is describe for collecting energy in electromagnetic radiation, where the device includes a first panel that includes a first height, a first end, and a second end such that a first length is defined between the first end and the second end. The device further includes a second panel that includes a second height, a third end, and a fourth end such that a second length is defined between the third end and the fourth end. In addition, the first height and the second height are substantially parallel to a reference axis, the first end and the third end intersect to form a leading edge that is substantially parallel to the reference axis, and the first panel and the second panel form a channel positioned between the first panel and the second panel. Further, the channel is configured for the flow of a first heat-transfer medium through the channel, and at least a part of the first panel and at least a part of the second panel are configured to absorb electromagnetic radiation to transfer energy from the electromagnetic radiation to the first heat-transfer medium. |
| FILED | Monday, December 26, 2016 |
| APPL NO | 15/390690 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 10/55 (20180501) Original (OR) Class F24S 20/20 (20180501) F24S 70/60 (20180501) F24S 80/20 (20180501) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/41 (20130101) Y02E 10/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422584 | Williamson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rodney L. Williamson (Albuquerque, New Mexico); David K. Melgaard (Albuquerque, New Mexico); Joseph J. Beaman (Austin, Texas) |
| ASSIGNEE(S) | Specialty Metals Processing Consortium (Albuquerque, New Mexico) |
| INVENTOR(S) | Rodney L. Williamson (Albuquerque, New Mexico); David K. Melgaard (Albuquerque, New Mexico); Joseph J. Beaman (Austin, Texas) |
| ABSTRACT | A Vacuum Arc Remelting controller apparatus wherein process control is accomplished primarily through control of pool power. Pool power being defined as the total energy flux into a top ingot surface of the VAR ingot. The controller apparatus of the present invention comprises a controller computer that transmits commands to the host furnace through an ethernet connection. |
| FILED | Tuesday, March 24, 2015 |
| APPL NO | 14/666378 |
| ART UNIT | 3742 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Furnaces, Kilns, Ovens, or Retorts in General; Open Sintering or Like Apparatus F27B 3/085 (20130101) Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 11/08 (20130101) F27D 19/00 (20130101) Original (OR) Class F27D 21/00 (20130101) F27D 2007/066 (20130101) F27D 2019/0028 (20130101) F27D 2019/0037 (20130101) F27D 2019/0096 (20130101) F27D 2099/0021 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 7/144 (20130101) H05B 7/152 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/256 (20151101) Y02P 10/259 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422590 | Staats, Jr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Wayne Lawrence Staats, Jr. (Livermore, California) |
| ABSTRACT | The various technologies presented herein relate to fabrication and operation of a heat exchanger that is configured to extract heat from an underlying substrate. Heat can be extracted by way of an air gap formed between an impeller and a baseplate. By utilizing a pump to create an initial air gap that is further maintained by rotation of the impeller relative to the baseplate, a spring can be utilized that can apply a force of greater magnitude to the impeller than is used in a conventional approach, thus enabling the weight of the impeller to be negligible with respect to a width of the air gap, thereby conferring the desirable feature of orientation independence with respect to gravity with no performance degradation. |
| FILED | Tuesday, September 26, 2017 |
| APPL NO | 15/715997 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 17/04 (20130101) F16C 19/06 (20130101) F16C 21/00 (20130101) F16C 32/06 (20130101) F16C 32/0603 (20130101) F16C 32/0614 (20130101) F16C 32/0622 (20130101) F16C 32/0625 (20130101) F16C 2360/46 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/02 (20130101) Original (OR) Class F28F 5/00 (20130101) F28F 27/00 (20130101) F28F 2250/08 (20130101) F28F 2280/10 (20130101) Dynamo-electric Machines H02K 9/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422888 | Ianakiev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Kiril D. Ianakiev (Los Alamos, New Mexico); Martyn Thomas Swinhoe (Los Alamos, New Mexico); Markus Peter Hehlen (Los Alamos, New Mexico); Metodi Iliev (Los Alamos, New Mexico); Andrea Favalli (Los Alamos, New Mexico) |
| ABSTRACT | Devices/apparatuses are disclosed that include a photoemitting component, a photosensitive component deposited on the photoemitting component, a charge collection component, and a hollow enclosure for housing the photoemitting component, the photosensitive component, the charge collection component, or combinations thereof. Methods for making and using the apparatuses are also disclosed. |
| FILED | Thursday, June 30, 2016 |
| APPL NO | 15/198719 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/2002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422896 | Ianakiev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Kiril Ianakiev (Los Alamos, New Mexico); Metodi Iliev (Los Alamos, New Mexico); Martyn Swinhoe (Los Alamos, New Mexico); Michael Browne (Los Alamos, New Mexico); Adrienne LaFleur (Los Alamos, New Mexico) |
| ABSTRACT | Improved, high count rate thermal neutron counters and electronics enabling new, higher measurement capabilities are disclosed. Next generation 3He and 10B tubes may include an electronics package capable of operating at higher count rates and in higher gamma fields and providing more efficient use of 3He gas. Conventional detector systems may also be upgraded, providing a possible solution to measure spent nuclear fuel with high neutron efficiency previously not possible in 235U fission counter systems. Switching the number of tubes per amplifier allows use of the measured nuclear material for a calibration standard for dead time correction, increasing accuracy of neutron measurements systems. An optimized detector geometry and advanced electronics with double pulse filtering and a dual channel readout may be provided. A bipolar shaper may improve dead time, provide efficient detector use, reduce double pulsing, facilitate high count rate measurements, and allow remote threshold setting. |
| FILED | Monday, October 23, 2017 |
| APPL NO | 15/791297 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 3/008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10423126 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Rush D. Robinett, III (Tijeras, New Mexico); Ossama Abdelkhalik (Houghton, Michigan); Jiajun Song (Houghton, Michigan) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Michigan Technological University (Houghton, Michigan) |
| INVENTOR(S) | David G. Wilson (Tijeras, New Mexico); Rush D. Robinett, III (Tijeras, New Mexico); Ossama Abdelkhalik (Houghton, Michigan); Jiajun Song (Houghton, Michigan); Giorgio Bacelli (Albuquerque, New Mexico) |
| ABSTRACT | A multi-resonant wide band controller decomposes the wave energy converter control problem into sub-problems; an independent single-frequency controller is used for each sub-problem. Thus, each sub-problem controller can be optimized independently. The feedback control enables actual time-domain realization of multi-frequency complex conjugate control. The feedback strategy requires only measurements of the buoy position and velocity. No knowledge of excitation force, wave measurements, nor wave prediction is needed. As an example, the feedback signal processing can be carried out using Fast Fourier Transform with Hanning windows and optimization of amplitudes and phases. Given that the output signal is decomposed into individual frequencies, the implementation of the control is very simple, yet generates energy similar to the complex conjugate control. |
| FILED | Monday, December 04, 2017 |
| APPL NO | 15/830752 |
| ART UNIT | 2115 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Machines or Engines for Liquids F03B 13/16 (20130101) F03B 13/22 (20130101) F03B 15/00 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2270/20 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 11/38 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/142 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10423151 | Wyman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Richard P. Wyman (Idaho Falls, Idaho) |
| ABSTRACT | An architecture for a control system in a network, and devices and techniques for implementing the same. The architecture may comprise a logic controller isolated from the network by an interface controller and a bridge interface between the interface controller and the logic controller. |
| FILED | Friday, July 07, 2017 |
| APPL NO | 15/644118 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 21/004 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/054 (20130101) G05B 19/418 (20130101) Original (OR) Class G05B 19/0426 (20130101) Electric Digital Data Processing G06F 13/12 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10423185 | Baone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Chaitanya Ashok Baone (Glenville, New York); Herman Lucas Norbert Wiegman (Niskayuna, New York); Naresh Acharya (Niskayuna, New York) |
| ABSTRACT | A microgrid system includes one or more power generators configured to provide electrical energy. The microgrid system also includes a localized distribution network coupled to the one or more power generators, coupled to the one or more loads, and coupled to an external grid. The microgrid system further includes a microgrid controller configured to predict microgrid demand for the one or more loads for a predetermined period of time. The microgrid controller is also configured to receive demand information for the external grid for the predetermined period of time. The microgrid controller is further configured to determine an operation plan for the one or more power generators based on the predicted microgrid demand and the received demand information. Moreover, the microgrid controller is configured to determine a schedule to transmit electrical energy to the external grid based on the operation plan. |
| FILED | Wednesday, July 27, 2016 |
| APPL NO | 15/220749 |
| ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/042 (20130101) G05B 2219/40458 (20130101) Systems for Regulating Electric or Magnetic Variables G05F 1/66 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/06 (20130101) H02J 3/38 (20130101) H02J 4/00 (20130101) H02J 2003/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424471 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Richard D. Smith (Richland, Washington); Sandilya V. B. Garimella (Richland, Washington); Yehia M. Ibrahim (Richland, Washington) |
| ABSTRACT | An apparatus includes a flexible ion conduit extending between an input end situated to receive ions and an output end to define an ion passageway having an axis, the flexible ion conduit including an inner conduit portion having an inner surface facing the interior ion passageway and having a plurality of RF electrodes adjacently situated to receive RF voltages that are out of phase with respect to each other to direct the received ions away from the inner surface and into the ion passageway. |
| FILED | Tuesday, June 26, 2018 |
| APPL NO | 16/019397 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/062 (20130101) Original (OR) Class H01J 49/142 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424474 | Ibrahim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Yehia M. Ibrahim (Richland, Washington); Sandilya V. B. Garimella (Richland, Washington); Richard D. Smith (Richland, Washington) |
| ABSTRACT | Methods and devices for ion separations or manipulations in gas phase are disclosed. The device includes a non-planar surface having a first, second and third region. An inner arrays of electrodes is positioned on the first region. A first set of electrodes of the inner array of electrodes is configured to receive RF voltages and generate a first potential upon the receipt of the RF voltage. A first and second outer arrays of electrodes are coupled to the second and third region, respectively. The first and second outer arrays are configured to receive a first DC voltage and generate a second potential upon the receipt of the first DC voltages. The first and second generated potential manipulate movement of ions. |
| FILED | Monday, May 02, 2016 |
| APPL NO | 15/759194 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0013 (20130101) H01J 49/022 (20130101) H01J 49/26 (20130101) Original (OR) Class H01J 49/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424572 | Rogers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Semprius, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); X-Celeprint Limited (Cork, Ireland) |
| INVENTOR(S) | John Rogers (Champaign, Illinois); Ralph Nuzzo (Champaign, Illinois); Matthew Meitl (Durham, North Carolina); Etienne Menard (Durham, North Carolina); Alfred Baca (Urbana, Illinois); Michael Motala (Champaign, Illinois); Jong-Hyun Ahn (Suwon, South Korea); Sang-Il Park (Savoy, Illinois); Chang-Jae Yu (Urbana, Illinois); Heung Cho Ko (Gwangju, South Korea); Mark Stoykovich (Dover, New Hampshire); Jongseung Yoon (Urbana, Illinois) |
| ABSTRACT | Provided are optical devices and systems fabricated, at least in part, via printing-based assembly and integration of device components. In specific embodiments the present invention provides light emitting systems, light collecting systems, light sensing systems and photovoltaic systems comprising printable semiconductor elements, including large area, high performance macroelectronic devices. Optical systems of the present invention comprise semiconductor elements assembled, organized and/or integrated with other device components via printing techniques that exhibit performance characteristics and functionality comparable to single crystalline semiconductor based devices fabricated using conventional high temperature processing methods. Optical systems of the present invention have device geometries and configurations, such as form factors, component densities, and component positions, accessed by printing that provide a range of useful device functionalities. Optical systems of the present invention include devices and device arrays exhibiting a range of useful physical and mechanical properties including flexibility, shapeability, conformability and stretchablity. |
| FILED | Tuesday, January 10, 2017 |
| APPL NO | 15/402684 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/0185 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/00 (20130101) H01L 25/042 (20130101) H01L 25/50 (20130101) Original (OR) Class H01L 25/167 (20130101) H01L 25/0753 (20130101) H01L 27/124 (20130101) H01L 27/1214 (20130101) H01L 27/1285 (20130101) H01L 27/1292 (20130101) H01L 27/14627 (20130101) H01L 27/14636 (20130101) H01L 27/14643 (20130101) H01L 29/78603 (20130101) H01L 29/78681 (20130101) H01L 31/043 (20141201) H01L 31/167 (20130101) H01L 31/0288 (20130101) H01L 31/0525 (20130101) H01L 31/0543 (20141201) H01L 31/0547 (20141201) H01L 31/0693 (20130101) H01L 31/0725 (20130101) H01L 31/1804 (20130101) H01L 31/1824 (20130101) H01L 31/1868 (20130101) H01L 31/1876 (20130101) H01L 31/1892 (20130101) H01L 31/02005 (20130101) H01L 31/02008 (20130101) H01L 31/02168 (20130101) H01L 31/02325 (20130101) H01L 31/02327 (20130101) H01L 31/03046 (20130101) H01L 33/005 (20130101) H01L 33/06 (20130101) H01L 33/30 (20130101) H01L 33/52 (20130101) H01L 33/54 (20130101) H01L 33/56 (20130101) H01L 33/58 (20130101) H01L 33/62 (20130101) H01L 33/0079 (20130101) H01L 33/483 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2933/005 (20130101) H01L 2933/0058 (20130101) H01L 2933/0066 (20130101) H01L 2933/0091 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/021 (20130101) H01S 5/183 (20130101) H01S 5/423 (20130101) H01S 5/02284 (20130101) H01S 5/3013 (20130101) H01S 5/34326 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Y02E 10/547 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424714 | Kemp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Mark A. Kemp (Belmont, California); Matthew A. Franzi (Burlingame, California); Erik N. Jongewaard (Boulder Creek, California); Emilio A. Nanni (Redwood City, California); Andrew A. Haase (Belmont, California) |
| ABSTRACT | A piezoelectric dipole transmitter is provided that includes a piezoelectric element, an insulating support disposed at a midpoint of said piezoelectric element, or along the piezoelectric element, an external capacitance driver, and an external modulation capacitance disposed proximal to a first end of the piezoelectric element, where the driver capacitance is driven by a signal appropriate to excite a length-extensional acoustic mode of the piezoelectric element, where the piezoelectric element resonates at a piezoelectric element resonance frequency to radiate energy as an electric dipole. |
| FILED | Tuesday, November 27, 2018 |
| APPL NO | 16/201485 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/18 (20130101) H01L 41/044 (20130101) Original (OR) Class H01L 41/053 (20130101) H01L 41/107 (20130101) H01L 41/1873 (20130101) H01L 41/1876 (20130101) Transmission H04B 1/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424792 | Dudney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Nancy J. Dudney (Knoxville, Tennessee); Chengdu Liang (Knoxville, Tennessee); Jagjit Nanda (Knoxville, Tennessee); Gabriel M. Veith (Knoxville, Tennessee); Yoongu Kim (Highlands Ranch, Colorado); Surendra Kumar Martha (Knoxville, Tennessee) |
| ABSTRACT | A lithium ion battery includes an anode and a cathode. The cathode includes a lithium, manganese, nickel, and oxygen containing compound. An electrolyte is disposed between the anode and the cathode. A protective layer is deposited between the cathode and the electrolyte. The protective layer includes pure lithium phosphorus oxynitride and variations that include metal dopants such as Fe, Ti, Ni, V, Cr, Cu, and Co. A method for making a cathode and a method for operating a battery are also disclosed. |
| FILED | Thursday, January 26, 2017 |
| APPL NO | 15/416500 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/366 (20130101) H01M 4/0402 (20130101) H01M 4/0426 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/628 (20130101) Original (OR) Class H01M 4/1391 (20130101) H01M 10/42 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/4235 (20130101) H01M 2004/028 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/54 (20151101) Technical Subjects Covered by Former US Classification Y10T 29/49115 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424803 | Angell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Charles Austen Angell (Mesa, Arizona); Leigang Xue (Tempe, Arizona) |
| ABSTRACT | An ionic liquid catholyte includes an ionic liquid, such as 1-ethyl-3-methylimidazolium chloride (EMICl), at least one half of a redox couple, and a sodium salt. The ionic liquid catholyte is suitable for use as a liquid cathode in an electrochemical device including an anode current collector, an anode in contact with the anode current collector, a cathode current collector, a liquid cathode in contact with the cathode current collector, and a solid electrolyte separating the anode and cathode current collectors. The one half of the redox couple includes a metal in a first oxidation state that is oxidized or reduced to yield the metal in a second oxidation state, and the redox couple includes the metal in the first oxidation state and the metal in the second oxidation state. The solid electrolyte is permeable to sodium ions and is in contact with the liquid anode and the liquid cathode. |
| FILED | Tuesday, September 15, 2015 |
| APPL NO | 15/508032 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8652 (20130101) H01M 8/20 (20130101) H01M 8/188 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424804 | Tucker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael C. Tucker (Piedmont, California); Adam Z. Weber (Lafayette, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michael C. Tucker (Piedmont, California); Adam Z. Weber (Lafayette, California) |
| ABSTRACT | The Ce—H2 redox flow cell is optimized using commercially-available cell materials. Cell performance is found to be sensitive to the upper charge cutoff voltage, membrane boiling pretreatment, methanesulfonic-acid concentration, (+) electrode surface area and flow pattern, and operating temperature. Performance is relatively insensitive to membrane thickness, Cerium concentration, and all features of the (−) electrode including hydrogen flow. Cell performance appears to be limited by mass transport and kinetics in the cerium (+) electrode. Maximum discharge power of 895 mW cm−2 was observed at 60° C.; an energy efficiency of 90% was achieved at 50° C. The Ce—H2 cell is promising for energy storage assuming one can optimize Ce reaction kinetics and electrolyte. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 15/582225 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/0047 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/92 (20130101) H01M 4/9041 (20130101) H01M 8/188 (20130101) Original (OR) Class H01M 8/1004 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424805 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Jingjing Zhang (Willowbrook, Illinois); Lu Zhang (Lisle, Illinois); Ilya A. Shkrob (Chicago, Illinois) |
| ABSTRACT | The present invention provides a redox flow battery comprising a negative electrode (also referred to herein as an “anode”) immersed in a first liquid electrolyte (also referred to herein as a “negative electrolyte” or “anolyte”), a positive electrode (also referred to herein as a “cathode”) immersed in a second liquid electrolyte (also referred to herein as a “positive electrolyte” or “catholyte”), and a cation-permeable separator (e.g., a membrane or other cation-permeable material) partitioning the negative electrode/anolyte from the positive electrode/catholyte. The redox reactant of the catholyte comprises a compound of Formula (I) as described herein. |
| FILED | Tuesday, August 15, 2017 |
| APPL NO | 15/677255 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/023 (20130101) H01M 8/188 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424806 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Lu Zhang (Lisle, Illinois); Jinhua Huang (Willowbrook, Illinois); Anthony Burrell (Naperville, Illinois) |
| ABSTRACT | The present invention provides a non-aqueous redox flow battery comprising a negative electrode immersed in a non-aqueous liquid negative electrolyte, a positive electrode immersed in a non-aqueous liquid positive electrolyte, and a cation-permeable separator (e.g., a porous membrane, film, sheet, or panel) between the negative electrolyte from the positive electrolyte. During charging and discharging, the electrolytes are circulated over their respective electrodes. The electrolytes each comprise an electrolyte salt (e.g., a lithium or sodium salt), a transition-metal free redox reactant, and optionally an electrochemically stable organic solvent. The redox reactant of the positive electrolyte is a dialkoxybenzene compound, and the redox reactant of the negative electrolyte is a viologen compound or a dipyridyl ketone. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 15/962563 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9008 (20130101) H01M 8/20 (20130101) H01M 8/188 (20130101) Original (OR) Class H01M 2300/0028 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10425018 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhong Lin Wang (Atlanta, Georgia); Xiaonan Wen (Atlanta, Georgia); Weiqing Yang (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Zhong Lin Wang (Atlanta, Georgia); Xiaonan Wen (Atlanta, Georgia); Weiqing Yang (Atlanta, Georgia) |
| ABSTRACT | A triboelectric generator includes a first triboelectric member, which includes a first conductive layer and an insulating triboelectric material layer disposed on the first conductive layer. The triboelectric material layer includes a first material having a first position on a triboelectric series. An elastic member, disposed against the triboelectric material layer of the triboelectric member and includes a second conductive material, has an elasticity that results in the elastic member being deformed when compressed and returning to an original non-deformed shape after being compressed. The second conductive material has a second position on the triboelectric series. A first load is coupled to the first conductive layer and with the second conductive material so that when a force compresses the elastic member charges will flow between the first conductive layer and the second conductive layer through the load. |
| FILED | Thursday, May 19, 2016 |
| APPL NO | 15/159225 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 1/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10425742 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Qin Zhou (Fremont, California); Alexander Zettl (Kensington, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus associated with an electrostatically driven graphene speaker. In one aspect, a device includes a graphene membrane, a first frame on a first side of the graphene membrane, and a second frame on a second side of the graphene membrane. The first frame and the second frame both include substantially circular open regions that define a substantially circular portion of the graphene membrane. A first electrode is proximate the first side of the circular portion of the graphene membrane. A second electrode proximate the second side of the circular portion of the graphene membrane. |
| FILED | Friday, June 12, 2015 |
| APPL NO | 14/737903 |
| ART UNIT | 2651 — Videophones and Telephonic Communications |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 19/02 (20130101) H04R 19/005 (20130101) Original (OR) Class H04R 23/002 (20130101) H04R 29/001 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/733 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426043 | Girardi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Michael Girardi (Kansas City, Missouri) |
| ABSTRACT | A circuit board comprising a substrate and a circuit trace. The substrate includes a surface etched via ion milling over a circuit area such that the surface has an increased roughness. The circuit trace forms portions of an electronic circuit and may be created from a thin conductive film deposited on the surface within the circuit area. The circuit trace adheres more strongly to the roughened substrate surface, which prevents the circuit trace from peeling or becoming delaminated from the substrate surface. |
| FILED | Friday, August 19, 2016 |
| APPL NO | 15/241336 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0298 (20130101) H05K 1/0306 (20130101) H05K 3/16 (20130101) H05K 3/0017 (20130101) H05K 3/027 (20130101) H05K 3/146 (20130101) H05K 3/381 (20130101) Original (OR) Class H05K 2201/0317 (20130101) H05K 2203/092 (20130101) H05K 2203/0522 (20130101) H05K 2203/0585 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10420495 | Cooks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Zheng Ouyang (West Lafayette, Indiana); Chien-hsun Chen (West Lafayette, Indiana); Ziqing Lin (West Lafayette, Indiana); Livia Schiavinato Eberlin (Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member. |
| FILED | Tuesday, January 15, 2019 |
| APPL NO | 16/248066 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/145 (20130101) A61B 5/157 (20130101) A61B 5/1405 (20130101) A61B 5/1477 (20130101) Original (OR) Class A61B 5/150015 (20130101) A61B 5/150992 (20130101) A61B 10/0045 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/00 (20130101) A61M 25/00 (20130101) A61M 2202/0468 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) G01N 2001/028 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0022 (20130101) H01J 49/34 (20130101) H01J 49/167 (20130101) H01J 49/0404 (20130101) H01J 49/0445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420819 | Soliman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| ASSIGNEE(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| INVENTOR(S) | Tarik Soliman (Cambridge, Massachusetts); Laura M. Hales (Cambridge, Massachusetts); Daniel B. Hall (Easton, Massachusetts); Howard Sard (Arlington, Massachusetts); Vishnumurthy Hegde (Chelmsford, Massachusetts) |
| ABSTRACT | The invention provides non-hormonal vitamin D conjugated to insulin peptides that result in the peptides having increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. The vitamin D targeting groups are coupled to the insulin peptides via the third carbon on the vitamin D backbone. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/468083 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/28 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/64 (20170801) A61K 47/551 (20170801) Peptides C07K 14/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420856 | Arinzeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| ASSIGNEE(S) | New Jersey Institute of Technology (, None) |
| INVENTOR(S) | Treena Arinzeh (West Orange, New Jersey); George Collins (Maplewood, New Jersey); Yee-Shuan Lee (Kearny, New Jersey) |
| ABSTRACT | Provided is an electroactive structure and method for growing isolated differentiable cells comprising a three dimensional matrix of fibers formed of a biocompatible synthetic piezoelectric polymeric material, wherein the matrix of fibers is seeded with the isolated differentiable cells and forms a supporting scaffold for growing the isolated differentiable cells, and wherein the matrix of fibers stimulates differentiation of the isolated differentiable cells into a mature cell phenotype on the structure. |
| FILED | Monday, August 22, 2016 |
| APPL NO | 15/242711 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) Original (OR) Class A61L 27/16 (20130101) A61L 27/16 (20130101) A61L 27/54 (20130101) A61L 27/3834 (20130101) A61L 2300/414 (20130101) A61L 2400/12 (20130101) A61L 2430/02 (20130101) A61L 2430/06 (20130101) Compositions of Macromolecular Compounds C08L 27/12 (20130101) C08L 27/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0618 (20130101) C12N 5/0668 (20130101) C12N 2529/00 (20130101) C12N 2533/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420885 | Sia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia in the City of New York (New York, New York) |
| INVENTOR(S) | Samuel K. Sia (New York, New York); Sau Yin Chin (Bronx, New York); Anne-Celine Kohler (Paris, France); Yuk Kee Cheung Poh (Cambridge, Massachusetts) |
| ABSTRACT | MicroElectroMechanical System (MEMS) devices can be fabricated completely of hydrogel materials. Such hydrogels can include polyethylene glycol with diacrylate functional groups (e.g., PEGDA), which are photopolymerizable in the presence of crosslinkers and photoinitiators. By using PEGDA monomers of different molecular weights and at different percentages, the mechanical properties of the polymerized gels and their respective permeabilities can be tuned. This spatial variation in properties and permeabilities can lead to different functionalities between different portions of the hydrogel MEMS device. Portions of the hydrogel device may be remotely actuated by applying wave energy, for example, a magnetic field, high intensity focused ultrasound, and/or infrared radiation. The remote actuation can allow the device to be actuated in vivo, for example, to allow the device to deliver a drug or other substance at a desired time and/or desired location within a patient. |
| FILED | Tuesday, January 16, 2018 |
| APPL NO | 15/872649 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14276 (20130101) A61M 5/16813 (20130101) Original (OR) Class A61M 2205/0244 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10420918 | Rodgers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Victor G. J. Rodgers (Riverside, California); Devin Binder (Riverside, California); Devin McBride (Riverside, California); Michael Hsu (Riverside, California); B. Hyle Park (Riverside, California) |
| ABSTRACT | The invention provides compositions and methods for the treatment and/or reversal of an edema, e.g., including a central nervous system (CNS) edema, e.g., a brain or a spinal edema, edema in a burned or an injured tissue such as skin, or any tissue edema. In alternative embodiments, the invention provides compositions and methods for a direct treatment and reversal of an edema, e.g., CNS, brain or spinal edema, including a membrane transport device, in vitro and in vivo characterization of edema, and the sensitive early optical detection of the edema, e.g., tissue, CNS or cerebral edema. |
| FILED | Wednesday, November 12, 2014 |
| APPL NO | 14/539385 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/4878 (20130101) A61B 5/6868 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/38 (20130101) A61K 38/40 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/16 (20130101) A61L 29/043 (20130101) A61L 29/044 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 27/002 (20130101) Original (OR) Class A61M 2027/004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421072 | Megaridis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Constantine M. Megaridis (Oak Park, Illinois); Ranjan Ganguly (Oak Park, Illinois); Aritra Ghosh (Chicago, Illinois); Thomas Schutzius (Tinley Park, Illinois) |
| ABSTRACT | Provided herein are methods and materials for the manufacture and use of wettability tracks on various substrates for rapid fluid transport and drainage, even in a condensing environment. The degree of wettability of the materials' surfaces range from superhydrophobic to superhydrophilic. The method centers on the formation of a dispersion of titanium dioxide and a fluoroacrylic co-polymer in an alcohol and water solution. The dispersion may then be deposited onto a surface to form a coating, which is then dried to evaporate the alcohol. The dried coating is exposed to radiation to produce a wedge-shaped track. The coating is exposed to the radiation through a photomask to produce the track. The radiation may be high energy, such as UV radiation. The radiation may be selectively exposed to designated areas on the coating. The hydrophilic wedge-shaped track may have a wedge angle of from 0 degrees to 45 degrees. |
| FILED | Wednesday, January 21, 2015 |
| APPL NO | 15/112958 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 3/502707 (20130101) B01L 3/502746 (20130101) B01L 2200/12 (20130101) B01L 2200/0605 (20130101) B01L 2300/12 (20130101) B01L 2300/089 (20130101) B01L 2300/126 (20130101) B01L 2300/161 (20130101) B01L 2300/166 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0883 (20130101) B01L 2400/088 (20130101) B01L 2400/0406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2015/1006 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/2575 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421675 | Hashim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel Paul Hashim (Deer Park, New York); Pulickel M. Ajayan (Houston, Texas); Mauricio Terrones (State College, Pennsylvania) |
| ASSIGNEE(S) | CSS Nanotech, Inc. (Houston, Texas) |
| INVENTOR(S) | Daniel Paul Hashim (Deer Park, New York); Pulickel M. Ajayan (Houston, Texas); Mauricio Terrones (State College, Pennsylvania) |
| ABSTRACT | Methods for synthesizing macroscale 3D heteroatom-doped carbon nanotube materials (such as boron doped carbon nanotube materials) and compositions thereof. Macroscopic quantities of three-dimensionally networked heteroatom-doped carbon nanotube materials are directly grown using an aerosol-assisted chemical vapor deposition method. The porous heteroatom-doped carbon nanotube material is created by doping of heteroatoms (such as boron) in the nanotube lattice during growth, which influences the creation of elbow joints and branching of nanotubes leading, to the three dimensional super-structure. The super-hydrophobic heteroatom-doped carbon nanotube sponge is strongly oleophilic and can soak up large quantities of organic solvents and oil. The trapped oil can be burnt off and the heteroatom-doped carbon nanotube material can be used repeatedly as an oil removal scaffold. Optionally, the heteroatom-doped carbon nanotubes in the heteroatom-doped carbon nanotube materials can be welded to form one or more macroscale 3D carbon nanotubes. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/369022 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/205 (20130101) B01J 20/0248 (20130101) B01J 20/0259 (20130101) B01J 20/0266 (20130101) B01J 2220/42 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/16 (20170801) C01B 35/00 (20130101) C01B 2202/30 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/281 (20130101) C02F 1/283 (20130101) C02F 1/288 (20130101) C02F 1/681 (20130101) Original (OR) Class C02F 2101/32 (20130101) C02F 2103/007 (20130101) C02F 2103/08 (20130101) C02F 2305/08 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/32 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 10/37 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421951 | Pfleger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Brian F. Pfleger (Madison, Wisconsin); Nestor Jose Hernandez-Lozada (Madison, Wisconsin); Costas Maranas (State College, Pennsylvania); Matthew Grisewood (Mountaintop, Pennsylvania) |
| ABSTRACT | Unnatural, mutated thioesterases having an amino acid sequence that is at least 80% identical to SEQ. ID. NO: 1 and having substitutions at one or more of amino acid positions I107, R108, L109, S122, M141, E142, Y145, and L146, gene constructs encoding and configured to express the mutated thioesterases in a transformed host cell and host cells transformed to contain the gene constructs. |
| FILED | Thursday, June 22, 2017 |
| APPL NO | 15/630442 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/02002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421954 | Kirshenbaum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Kent Kirshenbaum (New York, New York); Paul Levine (Los Angeles, California); Timothy Craven (Randolph, New Jersey) |
| ABSTRACT | Novel hybrid polymers are disclosed that have a structure represented by the following formula I: wherein Abiotic oligomer, Polypeptide, X, Y, and R1 are as described herein. The methods to prepare the hybrid polymers via novel oxazolidinyl compounds are also described. |
| FILED | Friday, September 30, 2016 |
| APPL NO | 15/281202 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 1/13 (20130101) C07K 1/026 (20130101) C07K 5/081 (20130101) C07K 5/0806 (20130101) C07K 7/06 (20130101) C07K 7/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421973 | McDonald et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents Of The University Of California (Oakland, California) |
| INVENTOR(S) | Karen A. McDonald (Fairfield, California); Abhaya Dandekar (Davis, California); Bryce W. Falk (Davis, California); Mysore R. Sudarshana (Davis, California); Sandra L. Uratsu (Davis, California); Michael A. Plesha (Davis, California); Ting-Kuo Huang (Davis, California) |
| ABSTRACT | The invention relates to a novel chemically inducible plant viral amplicon (CMViva) expression system that permits controllable, high level expression of foreign genes in plant hosts. This system employs agro-infiltration of plants to provide a transient production of a protein of interest, such as a human blood protein. This system provides a major advantage over existing plant expression systems because it allows for consistent expression of foreign or heterologous proteins in plant hosts. |
| FILED | Monday, February 13, 2017 |
| APPL NO | 15/431562 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/8125 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8203 (20130101) Original (OR) Class C12N 15/8216 (20130101) C12N 15/8217 (20130101) C12N 15/8238 (20130101) C12N 15/8257 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421989 | Blanchard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York); UNIVERSITY OF INNSBRUCK (Innsbruck, Austria) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York); UNIVERSITY OF INNSBRUCK (Innsbruck, Austria) |
| INVENTOR(S) | Scott Blanchard (New York, New York); Roger Altman (New York, New York); Marie F. Souliere (Chavannes-pres-Renens, Switzerland); Ronald Micura (Innsbruck, Austria); Andrea Haller (Innsbruck, Austria) |
| ABSTRACT | We provide isolated TPP and preQ1 class II riboswitches which are labelled for FRET studies of ribosome function. The riboswitches may be used in assays to determine riboswitch function, and to test the activity of compounds in modulating riboswitch function. |
| FILED | Thursday, February 26, 2015 |
| APPL NO | 15/121815 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6818 (20130101) Original (OR) Class C12Q 2525/205 (20130101) C12Q 2525/301 (20130101) C12Q 2565/133 (20130101) C12Q 2565/1015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422054 | Lozano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Karen Lozano (Edinburg, Texas); Lee Daniel Cremar (McAllen, Texas); Maria del Rocio Nava Lara (Cuernavaca, Mexico); Mandana Akia (Edinburg, Texas) |
| ABSTRACT | A method of producing doped carbon fibers, doped systems to prepare graphene-fiber hybrid structures, or doped carbon nanostructures, includes forming doped polymer precursors and decomposing at least a portion of the polymeric precursors to form carbon fibers. The decomposition may be accomplished by treating the doped polymer precursors with acid vapor from an aqueous acid solution at a temperature of less than 250° C. |
| FILED | Thursday, September 22, 2016 |
| APPL NO | 15/273113 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/18 (20170801) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/18 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) D01F 9/14 (20130101) Original (OR) Class D01F 9/21 (20130101) D01F 11/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422124 | Alfattani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rami A. Alfattani (Makkah, Saudi Arabia); Craig Lusk (Lutz, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Rami A. Alfattani (Makkah, Saudi Arabia); Craig Lusk (Lutz, Florida) |
| ABSTRACT | A bistable collapsible compliant mechanism including a first sub-mechanism comprising opposed first and second quaternary links and multiple binary links, each link being connected to at least two other links in the sub-mechanism, and a second sub-mechanism connected to the first sub-mechanism, the second sub-mechanism also comprising opposed first and second quaternary links and multiple binary links, each link being connected to at least two other links in the sub-mechanism, wherein the bistable collapsible compliant mechanism can be alternatively be placed in a stable extended orientation in which the bistable collapsible compliant mechanism has a trapezoidal shape and in a stable contracted orientation in which the bistable collapsible compliant mechanism has a polygonal spiral shape. |
| FILED | Friday, May 12, 2017 |
| APPL NO | 15/594132 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/344 (20130101) E04B 1/34357 (20130101) Original (OR) Class Gearing F16H 21/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422792 | Schwartz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Daniel K. Schwartz (Boulder, Colorado); Patrick S. Noonan (Golden, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| INVENTOR(S) | Daniel K. Schwartz (Boulder, Colorado); Patrick S. Noonan (Golden, Colorado) |
| ABSTRACT | The present invention provides methods, devices and kits for detecting binding between two molecules using a liquid crystal. |
| FILED | Thursday, March 19, 2015 |
| APPL NO | 15/121750 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/23 (20130101) G01N 33/5308 (20130101) Original (OR) Class G01N 2333/974 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10423129 | Huynh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Vu Anh Huynh (Canbridge, Massachusetts); Emilio Frazzoli (Cambridge, Massachusetts) |
| ABSTRACT | A computer-based method controls a dynamical system in an uncertain environment within a bounded probability of failure. The dynamical system has a state space and a control space. The method includes diffusing a risk constraint corresponding to the bounded probability of failure into a martingale that represents a level of risk tolerance associated with the dynamical system over time. The state space and the control space of the dynamical system are augmented with the martingale to create an augmented model with an augmented state space and an augmented control space. The method may include iteratively constructing one or more Markov Decision Processes (MDPs), with each iterative MDP represents an incrementally refined model of the dynamical system. The method further includes computing a first solution based on the augmented model or, if additional time was available, based on one of the MDP iterations. |
| FILED | Wednesday, July 26, 2017 |
| APPL NO | 15/660146 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/04 (20130101) Original (OR) Class G05B 23/0248 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424065 | Armeni et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Iro Armeni (Stanford, California); Ozan Sener (Stanford, California); Amir R. Zamir (Stanford, California); Martin Fischer (Stanford, California); Silvio Savarese (Stanford, California) |
| ABSTRACT | Systems and methods for performing three-dimensional semantic parsing of indoor spaces in accordance with embodiments of the invention are disclosed. In one embodiment, a method includes receiving input data representing a three-dimensional space, determining disjointed spaces within the received data by generating a density histogram on each of a plurality of axes, determining space dividers based on the generated density histogram, and dividing the point cloud data into segments based on the determined space dividers, and determining elements in the disjointed spaces by aligning the disjointed spaces within the point cloud data along similar axes to create aligned versions of the disjointed spaces normalizing the aligned version of the disjointed spaces into the aligned version of the disjointed spaces, determining features in the disjointed spaces, generating at least one detection score, and filtering the at least one detection score to determine a final set of determined elements. |
| FILED | Friday, June 09, 2017 |
| APPL NO | 15/619422 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/32 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/42 (20130101) G06K 9/4642 (20130101) G06K 9/6285 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) Original (OR) Class G06T 7/162 (20170101) G06T 7/187 (20170101) G06T 11/206 (20130101) G06T 19/00 (20130101) G06T 2207/10024 (20130101) G06T 2207/10028 (20130101) G06T 2207/20072 (20130101) G06T 2207/20221 (20130101) G06T 2210/04 (20130101) G06T 2210/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10425106 | Halbawi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Wael Halbawi (Pasadena, California); Babak Hassibi (San Marino, California); Zihan Liu (Berkeley, California) |
| ABSTRACT | Balanced Reed-Solomon codes in accordance with embodiments of the invention enable balanced load in distributed storage systems. One embodiment includes a storage controller, wherein the storage processor is configured by the controller Reed-Solomon application to: receive a data segment; partition the data segment into a first block of data and a second block of data; transmit the first block of data to a first node controller in the plurality of node controllers; transmit the second block of data to a second node controller in the plurality of node controllers; wherein the node processor in the first node controller is configured by the node Reed-Solomon application to: receive the first block of data; encode the first block of data using a balanced and sparsest error-correcting code; and store the encoded first block of data in the node memory of the first node controller. |
| FILED | Tuesday, November 28, 2017 |
| APPL NO | 15/824948 |
| ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1044 (20130101) G06F 11/1076 (20130101) G06F 2211/1028 (20130101) G06F 2211/1057 (20130101) Coding; Decoding; Code Conversion in General H03M 13/1515 (20130101) Original (OR) Class H03M 13/3761 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10425348 | Keller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| INVENTOR(S) | Eric Keller (Louisville, Colorado); Blake Caldwell (Boulder, Colorado); Murad Kablan (Boulder, Colorado) |
| ABSTRACT | Systems and methods are described for stateless network function virtualization. Embodiments operate in context of a data network, in which network middleboxes are virtualized, for example, for added scalability and fault tolerance. The virtualized middleboxes can implement state-reliant network functions in a manner that decouples the state from the packet processing pipeline, while maintaining reliability and throughput even at very high data rates. Various embodiments include novel packet processing pipeline architectures, novel thread coordination structures (e.g., including batching and buffer pool sub-structures), novel remote state data store structures, and/or other novel features. |
| FILED | Tuesday, July 26, 2016 |
| APPL NO | 15/220129 |
| ART UNIT | 2458 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4843 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 47/621 (20130101) Original (OR) Class H04L 49/901 (20130101) H04L 67/2876 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10425742 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Qin Zhou (Fremont, California); Alexander Zettl (Kensington, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus associated with an electrostatically driven graphene speaker. In one aspect, a device includes a graphene membrane, a first frame on a first side of the graphene membrane, and a second frame on a second side of the graphene membrane. The first frame and the second frame both include substantially circular open regions that define a substantially circular portion of the graphene membrane. A first electrode is proximate the first side of the circular portion of the graphene membrane. A second electrode proximate the second side of the circular portion of the graphene membrane. |
| FILED | Friday, June 12, 2015 |
| APPL NO | 14/737903 |
| ART UNIT | 2651 — Videophones and Telephonic Communications |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 19/02 (20130101) H04R 19/005 (20130101) Original (OR) Class H04R 23/002 (20130101) H04R 29/001 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/733 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE47622 | Sternberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Arizona Board of Regents on Behalf of University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Ben K. Sternberg (Tucson, Arizona); Steven L. Dvorak (Tucson, Arizona); Oleg Krichenko (Volgograd, Russian Federation) |
| ABSTRACT | A target is sensed by an antenna array having a transmitter antenna and a receiver antenna, both of which are caused to be electromagnetically coupled to the target. The antenna array is rotated, and as the array rotates, a change in at least one of the coupling between the transmitter antenna and the target and the coupling between the receiver antenna and the target is detected at multiple rotational orientations of the antenna array. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 15/720619 |
| ART UNIT | 3993 — Central Reexamination Unit (Mechanical) |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/104 (20130101) Antennas, i.e Radio Aerials H01Q 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10420465 | Stone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Leland S. Stone (San Francisco, California); Dorion B. Liston (Boulder Creek, California) |
| ABSTRACT | Various conditions, such as traumatic brain injuries (TBI), diseases, injuries, and/or other impairments, may be diagnosed by deriving a sensitive overall indicator of impairment of sensorimotor functional status based on results of an eye-movement assessment test that includes an appropriately randomized, radial tracking task together with a broad set of oculometric measures. The oculometric measures may be combined to yield the sensitive overall indicator of a particular impairment state. More specifically, the oculometric measures may be vectorized to help diagnose both the type of TBI, disease, or impairment and the extent thereof. |
| FILED | Monday, September 18, 2017 |
| APPL NO | 15/707561 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/032 (20130101) A61B 3/0041 (20130101) A61B 3/0091 (20130101) A61B 3/113 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421548 | McCarley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Michael C. McCarley (Titusville, Florida); Kent Clark (Cocoa, Florida); Melanie L. Weber (Melbourne, Florida); Norman G. Ring (Cocoa, Florida); Christopher Ferguson (Cape Canaveral, Florida) |
| ABSTRACT | An adjustable vehicle seat includes a seat frame forming a seat back, the seat frame being configured to couple with an aerospace vehicle; a seat pan coupled to the seat frame, where one or more of the seat frame and the seat pan is configured to couple the seat pan to the seat frame in one of a plurality of positions relative to the seat frame so that an eye position of a seat occupant relative to instrumentation within the aerospace vehicle is decoupled from a size of the seat occupant. |
| FILED | Friday, May 19, 2017 |
| APPL NO | 15/599739 |
| ART UNIT | 3616 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/386 (20170801) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/771 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 50/02 (20141201) B33Y 80/00 (20141201) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 11/062 (20141201) B64D 11/064 (20141201) Original (OR) Class B64D 11/0642 (20141201) B64D 11/0689 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/60 (20130101) B64G 1/62 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) G05B 2219/35134 (20130101) G05B 2219/49007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10422706 | Parker, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Adminstrator of the National Aeronautics and Space Adminstration (Washington, District of Columbia) |
| INVENTOR(S) | Allen R. Parker, Jr. (Lancaster, California); Anthony Piazza (Palmdale, California); Hon Man Chan (Canyon Country, California); Ryan M Warner (Lancaster, California) |
| ABSTRACT | The present invention is a temperature sensor for cryogenic systems using a fiber optic interrogation system that is capable of a large number of temperature readings across the cryogenic environment at high resolutions. The invention also includes a method of using such a system to measure temperatures in a cryogenic environment and a method of making such a system. |
| FILED | Thursday, June 28, 2018 |
| APPL NO | 16/021499 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/3206 (20130101) G01K 13/006 (20130101) Original (OR) Class Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/246 (20130101) Optical Elements, Systems, or Apparatus G02B 6/443 (20130101) G02B 6/02104 (20130101) G02B 6/02204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10424424 | Farrell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | James T. Farrell (Hermosa Beach, California); Thomas E. Musselman (Thousand Oaks, California); Martin W. Bieti (Tujunga, California); Paul J. Tatomir (Palm Desert, California) |
| ABSTRACT | Coaxial radio frequency (“RF”) connectors for high-power handling are disclosed. Specifically, a high-power male coaxial connector (“HPMC”) is disclosed. The HPMC includes a center conductor, an outer conductor disposed around the center conductor, an insulating layer positioned between the center conductor and the outer conductor, and a first elastomer. The outer conductor has an outer conductor front-end (“OCFE”) and the insulating layer has an insulating layer front-end (“ILFE”). The first elastomer is positioned between the center conductor and the insulating layer. The insulating layer may include an insulating layer cavity (“ILC”) extending inward into the insulating layer from the ILFE and the first elastomer may be within the ILC. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/626039 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 11/18 (20130101) H01B 11/1834 (20130101) Original (OR) Class Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/6584 (20130101) H01R 24/40 (20130101) H01R 24/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10420345 | Clapsaddle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TDA Research, Inc (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
| INVENTOR(S) | Brady Clapsaddle (Littleton, Colorado); Joe Fredrickson (Denver, Colorado); William Bell (Boulder, Colorado); Trevor Haanstad (Denver, Colorado); Jeff Martin (Arvada, Colorado) |
| ABSTRACT | The present invention provides a humidity tolerant CO2 generator that operates in combination with an arthropod trap. The CO2 generator comprises a means for controllably adding solid pellets to an aqueous acid solution, and optionally includes a sound-based counting system for counting the number of pellets dispensed from a feeder reservoir and into a reaction chamber. The invention also provides a method of using the same. |
| FILED | Tuesday, November 07, 2017 |
| APPL NO | 15/805850 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/10 (20130101) A01M 1/023 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 59/04 (20130101) Original (OR) Class Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 83/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421072 | Megaridis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Constantine M. Megaridis (Oak Park, Illinois); Ranjan Ganguly (Oak Park, Illinois); Aritra Ghosh (Chicago, Illinois); Thomas Schutzius (Tinley Park, Illinois) |
| ABSTRACT | Provided herein are methods and materials for the manufacture and use of wettability tracks on various substrates for rapid fluid transport and drainage, even in a condensing environment. The degree of wettability of the materials' surfaces range from superhydrophobic to superhydrophilic. The method centers on the formation of a dispersion of titanium dioxide and a fluoroacrylic co-polymer in an alcohol and water solution. The dispersion may then be deposited onto a surface to form a coating, which is then dried to evaporate the alcohol. The dried coating is exposed to radiation to produce a wedge-shaped track. The coating is exposed to the radiation through a photomask to produce the track. The radiation may be high energy, such as UV radiation. The radiation may be selectively exposed to designated areas on the coating. The hydrophilic wedge-shaped track may have a wedge angle of from 0 degrees to 45 degrees. |
| FILED | Wednesday, January 21, 2015 |
| APPL NO | 15/112958 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 3/502707 (20130101) B01L 3/502746 (20130101) B01L 2200/12 (20130101) B01L 2200/0605 (20130101) B01L 2300/12 (20130101) B01L 2300/089 (20130101) B01L 2300/126 (20130101) B01L 2300/161 (20130101) B01L 2300/166 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0883 (20130101) B01L 2400/088 (20130101) B01L 2400/0406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2015/1006 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/2575 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10421564 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Dongliang Yang (Ellicott City, Maryland); Shao C. Yang (Rockville, Maryland); Christopher R. Simpson (Olney, Maryland); James E. Goodbar, III (Springfield, Virginia); Marina E. Khazanov (Rockville, Maryland); George Coupar (Leesburg, Virginia) |
| ABSTRACT | Features for systems and methods for loading items into a tray are disclosed. The system may have an item conveyor configured to move the items towards a tray conveyor. The tray conveyor may be configured to move trays to receive items from the item conveyor into the tray. One or more sensors may detect the height of the items on the item conveyor and/or in the tray, and/or the position of the trays on the tray conveyor. A controller may receive data related to the one or more detected heights of the items and/or the position of the trays on the tray conveyor and correspondingly control movement of the item and/or tray conveyors for efficient loading of items into the tray and efficient movement of the trays for further processing. Tray conveyor movement sensors may detect movement of the trays or tray conveyors for further control or reliability of the system. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 15/799750 |
| ART UNIT | 3652 — Material and Article Handling |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/008 (20130101) Machines, Apparatus or Devices For, or Methods Of, Packaging Articles or Materials; Unpacking B65B 25/143 (20130101) Original (OR) Class B65B 43/54 (20130101) Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 65/00 (20130101) B65G 2201/0285 (20130101) Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables B65H 2701/1916 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10421630 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | John W. Brown (Manassas, Virginia); Edward F. Houston (Bristow, Virginia); Juan A. Roman (Fairfax, Virginia); Leung M. Shiu (Gaithersburg, Maryland); Riley H. Mayhall (Germantown, Maryland); Jacob L. Timm (Pasadena, Maryland); Reza Badri (Towson, Maryland); Thomas A. Hillerich (Louisville, Kentucky) |
| ABSTRACT | A device for reducing rotation of an article during singulation of a stack of articles is disclosed. The device may include a torsion element, a rotatable member configured to rotate about an elongated axis of the torsion element between a first position and a second position, and a revolving member coupled to the rotatable member. An outer surface of the revolving member contacts a drive belt in the first position and an article in the second position. The torsion element exerts torque on the rotatable member when it moves from the first position towards the second position. The torque causes the outer surface of the revolving member to apply a frictional force to the article, thereby minimizing rotation of the article. Systems and methods of singulating articles are also disclosed. |
| FILED | Thursday, August 03, 2017 |
| APPL NO | 15/668238 |
| ART UNIT | 3652 — Material and Article Handling |
| CURRENT CPC | Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables B65H 1/025 (20130101) B65H 3/66 (20130101) B65H 3/124 (20130101) Original (OR) Class B65H 7/16 (20130101) B65H 9/166 (20130101) B65H 2402/545 (20130101) B65H 2404/1521 (20130101) B65H 2404/1532 (20130101) B65H 2515/212 (20130101) B65H 2701/1916 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10424458 | Friedman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Lawrence H. Friedman (Silver Spring, Maryland); Wen-Li Wu (Gaithersburg, Maryland) |
| ABSTRACT | An electron reflectometer includes: a sample stage; a source that produces source electrons; a source collimator; and an electron detector that receives collimated reflected electrons. |
| FILED | Tuesday, May 15, 2018 |
| APPL NO | 15/980399 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 15/04 (20130101) G01B 2210/56 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/06 (20130101) H01J 37/10 (20130101) H01J 37/20 (20130101) H01J 37/22 (20130101) H01J 37/1471 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10420766 | Stauderman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CalciMedica, Inc. (La Jolla, California); VA MEDICAL CENTER (San Francisco, California) |
| ASSIGNEE(S) | CALCIMEDICA, INC. (La Jolla, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth Stauderman (San Diego, California); Michael Dunn (La Jolla, California); Sudarshan Hebbar (La Jolla, California); Midori Yenari (San Francisco, California); Rachid Kacimi (San Francisco, California) |
| ABSTRACT | Described herein are methods of treatment of stroke and traumatic brain injury comprising administration of a CRAC channel inhibitor. |
| FILED | Friday, August 05, 2016 |
| APPL NO | 15/751098 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/415 (20130101) A61K 31/422 (20130101) A61K 31/425 (20130101) A61K 31/427 (20130101) A61K 31/496 (20130101) A61K 31/497 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) A61P 9/10 (20180101) A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10422451 | Arvelo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Amilcar R. Arvelo (Poughkeepsie, New York); Michael J. Ellsworth, Jr. (Poughkeepsie, New York); Eric J. McKeever (Poughkeepsie, New York) |
| ABSTRACT | Tapering couplers and coupling methods for connecting fluid flow components are provided. In one embodiment, the tapering coupler includes a housing with a first opening and a second opening in fluid communication through the housing. The first opening is sized for a first fluid flow component to couple to the housing, and the second opening for a second fluid flow component. The first and second fluid flow components include first and second fluid-carrying channels of different diameter, with the first fluid-carrying channel having a first channel diameter that is larger than the second channel diameter of the second fluid-carrying channel. A tapering element is associated with the housing and extends into the first fluid-carrying channel. The tapering element includes a tapering fluid-carrying channel which tapers in a direction back towards the housing, for instance, from about the first channel diameter to about the second channel diameter. |
| FILED | Wednesday, September 10, 2014 |
| APPL NO | 14/482147 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/00 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 21/002 (20130101) Original (OR) Class F16L 25/14 (20130101) F16L 55/027 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20272 (20130101) H05K 7/20772 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 10422631 | Reaves et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LUNA INNOVATIONS INCORPORATED (Roanoke, Virginia) |
| ASSIGNEE(S) | Luna Innovations Incorporated (Roanoke, Virginia) |
| INVENTOR(S) | Matthew T. Reaves (Baltimore, Maryland); Brian M. Rife (Newport, Virginia); Evan M. Lally (Blacksburg, Virginia); Stephen T. Kreger (Blacksburg, Virginia) |
| ABSTRACT | An optical fiber includes primary optical core(s) having a first set of properties and secondary optical core(s) having a second set of properties. The primary set of properties includes a first temperature response, and the secondary set of properties includes a second temperature response sufficiently different from the first temperature response to allow a sensing apparatus when coupled to the optical fiber to distinguish between temperature and strain on the optical fiber. A method and apparatus interrogate an optical fiber having one or more primary optical cores with a first temperature response and one or more secondary optical cores with a second temperature response. Interferometric measurement data associated with each primary and secondary optical core are detected when the optical fiber is placed into a sensing position. Compensation parameter(s) is(are) determined to compensate for measurement errors caused by temperature variations along the optical fiber based on a difference between the first temperature response of the primary cores and the second temperature response of the secondary cores. The detected data are compensated using the compensation parameter(s). |
| FILED | Wednesday, November 11, 2015 |
| APPL NO | 15/525306 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/16 (20130101) Original (OR) Class Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/35303 (20130101) G01D 5/35316 (20130101) G01D 5/35361 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 11/3172 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10422793 | Johnston et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Arizona Board of Regents, A body Corporate of the State of Arizona for and on behalf of Arizona (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Stephen Albert Johnston (Tempe, Arizona); Phillip Stafford (Phoenix, Arizona) |
| ABSTRACT | The invention provides arrays of compound for use in profiling samples. The arrays include compounds bind to components of the samples at relatively low affinities. The avidity of compounds binding to components of the samples can be increased by forming arrays such that multivalent components of the samples (e.g., antibodies or cells) can bind to more than one molecule of a compound at the same time. When a sample is applied to an array under such conditions, the compounds of the array bind to component(s) of the sample with significantly different avidities generating a profile characteristic of the sample. |
| FILED | Friday, September 21, 2012 |
| APPL NO | 13/624332 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/543 (20130101) Original (OR) Class G01N 33/6845 (20130101) G01N 33/6854 (20130101) G01N 33/54306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10423650 | Moon |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Hankyu Moon (Oak Park, California) |
| ABSTRACT | Described is a system for identifying predictive keywords and generating a forecast. The system receives time-series of keyword counts (the time-series of keyword counts having a plurality of candidate keywords). The time-series of keyword counts are separated (i.e., marked or designated) into a group of time-series from active periods and a group of time-series from inactive periods. A covariance matrix is generated for each group of time-series. Generalized eigenvectors are generated between the two covariance matrices. Candidate keywords are ranked based on the generalized eigenvectors, such that candidate keywords having a rank exceeding a predetermined threshold are designated as predictive keywords. The predictive keywords are then provided to a machine learning system that generates a forecast based on the predictive keywords. Finally, a device is operated based on the forecast. |
| FILED | Thursday, October 26, 2017 |
| APPL NO | 15/795230 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 16/35 (20190101) G06F 16/337 (20190101) Original (OR) Class G06F 16/3346 (20190101) G06F 17/16 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 24, 2019.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20190924.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page