FedInvent™ Patents
Patent Details for Tuesday, October 01, 2019
This page was updated on Monday, March 27, 2023 at 05:54 AM GMT
Department of Health and Human Services (HHS)
| US 10426159 | Wen |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of California State University (Los Angeles, California) |
| ASSIGNEE(S) | The Trustees of California State University (Los Angeles, California) |
| INVENTOR(S) | Xin Wen (Alhambra, California) |
| ABSTRACT | New, highly efficient enhancers for AFPs have now been discovered in the form of co-enzymes, and active fragments and mimetics thereof. These enhancer molecules do not have TH activity themselves, but can enhance the TH activity of AFPs by at least about 2-11 times. These molecules are so far the most effective enhancers for AFPs, and are characterized by containing coenzymes or fragments or mimetic thereof. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 13/835734 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Original (OR) Class A01N 3/00 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 3/3472 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426331 | Jia et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (, None) |
| INVENTOR(S) | Yali Jia (Portland, Oregon); David Huang (Portland, Oregon); Miao Zhang (Portland, Oregon) |
| ABSTRACT | Disclosed are methods and systems for measuring areas of nonperfusion in the retina using OCT imaging. The disclosed methods and systems allow for the automated segmentation and quantification of avascular areas of the retina utilizing information obtained from both structural OCT and OCT angiography (OCTA) data. The disclosed methods include filtering approaches which enhance vessel structure while suppressing noise, dynamic thresholding approaches to mitigate the detrimental effects of within-scan variability and low scan quality, and distance transform-based approaches to improve detection of ischemic regions. When combined with methods such as projection-resolved OCTA, the sensitivity to detect nonperfusion within different plexuses of the inner retina is demonstrated. In the clinical setting of diabetic retinopathy, the disclosed methods and systems show high sensitivity and specificity to detect the mild non-proliferative form of the disease with high reproducibility. |
| FILED | Thursday, July 20, 2017 |
| APPL NO | 15/655040 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/0025 (20130101) Original (OR) Class A61B 3/102 (20130101) A61B 3/1233 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426374 | Bankiewicz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Krystof S. Bankiewicz (Oakland, California); Kathryn H. Rosenbluth (San Francisco, California); Adrian P Kells (San Francisco, California) |
| ABSTRACT | The present disclosure provides methods for targeting a biomedical system. Aspects of the subject methods include determining the trajectory of a targeting device using magnetic resonance imaging (MRI) of a MRI-visible style of a trajectory guide that is compatible with the targeting device. Targeted biomedical systems may be utilized for a variety of purposes including targeted delivery of a therapeutic, holding a therapeutic device, positioning of a therapeutic device and other uses. Also provided are devices and systems that can be used in practicing the described methods including but not limited to trajectory guides and adjustable targeting systems, as well as non-transitory computer readable medium storing instructions that, when executed by a computing device, cause a computing device to perform steps of the described methods. |
| FILED | Wednesday, July 18, 2018 |
| APPL NO | 16/039044 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/0555 (20130101) A61B 5/1071 (20130101) A61B 5/1072 (20130101) A61B 5/1127 (20130101) A61B 5/6835 (20130101) A61B 6/03 (20130101) A61B 6/04 (20130101) A61B 34/10 (20160201) A61B 90/11 (20160201) A61B 2017/00911 (20130101) A61B 2034/107 (20160201) A61B 2505/05 (20130101) A61B 2560/0475 (20130101) A61B 2576/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426375 | Bankiewicz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Krystof S. Bankiewicz (Oakland, California); Kathryn H. Rosenbluth (San Francisco, California); Adrian P. Kells (San Francisco, California) |
| ABSTRACT | The present disclosure provides methods for targeting a biomedical system. Aspects of the subject methods include determining the trajectory of a targeting device using magnetic resonance imaging (MRI) of a MRI-visible style of a trajectory guide that is compatible with the targeting device. Targeted biomedical systems may be utilized for a variety of purposes including targeted delivery of a therapeutic, holding a therapeutic device, positioning of a therapeutic device and other uses. Also provided are devices and systems that can be used in practicing the described methods including but not limited to trajectory guides and adjustable targeting systems, as well as non-transitory computer readable medium storing instructions that, when executed by a computing device, cause a computing device to perform steps of the described methods. |
| FILED | Monday, December 17, 2018 |
| APPL NO | 16/222763 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/0555 (20130101) A61B 5/1071 (20130101) A61B 5/1072 (20130101) A61B 5/1127 (20130101) A61B 5/6835 (20130101) A61B 6/03 (20130101) A61B 6/04 (20130101) A61B 34/10 (20160201) A61B 90/11 (20160201) A61B 2017/00911 (20130101) A61B 2034/107 (20160201) A61B 2505/05 (20130101) A61B 2560/0475 (20130101) A61B 2576/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426388 | Hasan et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Tayyaba Hasan (Boston, Massachusetts); Srivalleesha Mallidi (Boston, Massachusetts) |
| ABSTRACT | A method for measuring differential blood oxygen saturation in a solid tumor is described that includes the steps of obtaining a first oxygenation image of a solid tumor before, during, or immediately after a administration of vascular therapy; obtaining a second oxygenation image of the solid tumor after a devascularization time period; and determining a differential blood oxygen saturation value by comparing the first oxygenation image and the second oxygenation image. The differential blood oxygen saturation value can be compared to a blood oxygen saturation necrosis value to provide a prognosis for tumor recurrence, or to guide of the tumor. |
| FILED | Monday, February 02, 2015 |
| APPL NO | 15/114906 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0073 (20130101) A61B 5/0095 (20130101) A61B 5/4848 (20130101) A61B 5/7275 (20130101) A61B 5/14542 (20130101) A61B 5/14551 (20130101) Original (OR) Class A61B 2505/05 (20130101) A61B 2576/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426398 | Lieber et al. |
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| FUNDED BY |
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| APPLICANT(S) | REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Richard L. Lieber (Chicago, Illinois); Stojan Radic (San Diego, California); Kevin Young (San Diego, California) |
| ABSTRACT | Methods and systems for measuring muscle sarcomere length are disclosed. In an embodiment, a method comprises illuminating a set of muscle fibers with electromagnetic radiation, measuring an intensity of the electromagnetic radiation as reflected from the muscle fibers, the measuring occurring as a function of wavelength, determining wavelengths corresponding to maximums of reflected intensity, and correlating the determined wavelengths with respective muscle sarcomere lengths. In an embodiment, a system comprises an illumination source system for illuminating the set of muscle fibers with electromagnetic radiation, and an analyzer for measuring the intensity of the electromagnetic radiation as reflected from the muscle fibers. |
| FILED | Thursday, October 01, 2015 |
| APPL NO | 14/872906 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/0084 (20130101) A61B 5/1076 (20130101) A61B 5/1079 (20130101) A61B 5/4519 (20130101) Original (OR) Class A61B 2505/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426399 | Kayyali et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hani Kayyali (Shaker Heights, Ohio); Craig A. Frederick (Solon, Ohio); Christian Martin (Sandusky, Ohio); Robert N. Schmidt (Ft. Myers, Florida); Brian Kolkowski (Leroy, Ohio) |
| ASSIGNEE(S) | Cleveland Medial Devices Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Hani Kayyali (Shaker Heights, Ohio); Craig A. Frederick (Solon, Ohio); Christian Martin (Sandusky, Ohio); Robert N. Schmidt (Ft. Myers, Florida); Brian Kolkowski (Leroy, Ohio) |
| ABSTRACT | The present invention provides a method of conducting a sleep analysis by collecting physiologic and kinetic data from a subject, preferably via a wireless in-home data acquisition system, while the subject attempts to sleep at home. The sleep analysis, including clinical and research sleep studies and cardiorespiratory studies, can be used in the diagnosis of sleeping disorders and other diseases or conditions with sleep signatures, such as Parkinson's, epilepsy, chronic heart failure, chronic obstructive pulmonary disorder, or other neurological, cardiac, pulmonary, or muscular disorders. The method of the present invention can also be used to determine if environmental factors at the subject's home are preventing restorative sleep. |
| FILED | Friday, August 05, 2016 |
| APPL NO | 15/229242 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/0077 (20130101) A61B 5/085 (20130101) A61B 5/087 (20130101) A61B 5/0205 (20130101) A61B 5/0402 (20130101) A61B 5/0476 (20130101) A61B 5/0488 (20130101) A61B 5/0496 (20130101) A61B 5/1135 (20130101) A61B 5/4815 (20130101) Original (OR) Class A61B 5/6814 (20130101) A61B 5/6828 (20130101) A61B 5/14552 (20130101) A61B 2505/07 (20130101) A61B 2560/0242 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426403 | Butte et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of The Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Manish J. Butte (Stanford, California); Jayakumar Rajadas (Cupertino, California) |
| ABSTRACT | A method of testing for specificity and strength of an allergic reaction is performed by penetrating the skin of an individual with the microneedle array comprising a plurality of epitopes and determining the response of the skin to the allergens. The response can be measured with a thermal imaging device. Analysis, and optionally treatment, can be provided to the individual. |
| FILED | Thursday, May 08, 2014 |
| APPL NO | 14/888689 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/015 (20130101) A61B 5/0077 (20130101) A61B 5/411 (20130101) A61B 5/685 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) A61M 2037/0046 (20130101) A61M 2037/0053 (20130101) A61M 2037/0061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426482 | Rafiee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Nasser Rafiee (Andover, Massachusetts); Stuart MacDonald (Andover, Massachusetts); Robert J. Lederman (Bethesda, Maryland); Kanishka Ratnayaka (Bethesda, Maryland); Biwei MacDonald (Andover, Massachusetts); Alana Rafiee (Andover, Massachusetts) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Transmural Systems LLC (Andover, Massachusetts) |
| INVENTOR(S) | Nasser Rafiee (Andover, Massachusetts); Stuart MacDonald (Andover, Massachusetts); Robert J. Lederman (Bethesda, Maryland); Kanishka Ratnayaka (Bethesda, Maryland); Biwei MacDonald (Andover, Massachusetts); Alana Rafiee (Andover, Massachusetts) |
| ABSTRACT | In some implementations, a radially self-expanding endograft prosthesis is provided that includes (i) distal flange that is self-expanding and configured to flip generally perpendicularly with respect to a body of the prosthesis to help seat the prosthesis against a tissue wall, (ii) a distal segment extending proximally from the distal flange that has sufficient stiffness to maintain a puncture open that is formed through a vessel wall (iii) a compliant middle segment extending proximally from the distal segment, the middle segment being more compliant than the distal segment, and having independently movable undulating strut rings attached to a tubular fabric, the combined structure providing flexibility and compliance to allow for full patency while flexed, the segment being configured to accommodate up to a 90 degree bend, (iv) a proximal segment having a plurality of adjacent undulating strut rings that are connected to each other. |
| FILED | Thursday, September 15, 2016 |
| APPL NO | 15/267075 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/11 (20130101) Original (OR) Class A61B 2017/00252 (20130101) A61B 2017/1107 (20130101) A61B 2017/1139 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/07 (20130101) A61F 2002/828 (20130101) A61F 2002/91575 (20130101) A61F 2250/0082 (20130101) A61F 2250/0098 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426499 | Owen et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington Through Its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Neil Owen (Seattle, Washington); Michael Bailey (Seattle, Washington); Oleg Sapozhinikov (Seattle, Washington) |
| ABSTRACT | During shock wave therapy, a determination is made that a kidney stone has begun to fracture, and then a progress of its fragmentation is assessed. This determination can reduce the number of shock waves used to disintegrate kidney stones, and thereby reduce dose-dependent tissue damage. The identification of fracture is possible through the detection and analysis of resonant acoustic scattering, which is the radiation caused by reverberations within a stone particle that is struck by a shock wave. The scattering frequency can provide both an indication that the kidney stone has fragmented, and an indication of the relative sizes of the fragments. Related concepts employ displacement measurements of kidney stones/fragments to provide both an indication that the kidney stone has fragmented, and an indication of the relative sizes of the fragments. Such techniques can be combined with vibro-acoustography based gating that better targets the stone. |
| FILED | Wednesday, August 14, 2013 |
| APPL NO | 13/966535 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/06 (20130101) A61B 5/4848 (20130101) A61B 7/00 (20130101) A61B 7/04 (20130101) A61B 8/00 (20130101) A61B 8/13 (20130101) A61B 8/085 (20130101) A61B 8/0833 (20130101) A61B 17/225 (20130101) A61B 17/2255 (20130101) A61B 17/2256 (20130101) A61B 17/22004 (20130101) Original (OR) Class A61B 17/22012 (20130101) A61B 17/22029 (20130101) A61B 2017/22011 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) A61N 7/02 (20130101) A61N 7/022 (20130101) A61N 2007/0052 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/0016 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/35 (20130101) G10K 15/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426515 | Shivkumar |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Kalyanam Shivkumar (Los Angeles, California) |
| ABSTRACT | The present invention relates to systems and methods for accessing the left heart of a subject. For example, the invention includes a percutaneous inter-ventricular transseptal technique for accessing the left ventricle. In certain embodiments, the invention includes guiding a transseptal sheath to the right ventricle and positioning the transseptal sheath within the inter-ventricular septum. |
| FILED | Tuesday, December 23, 2014 |
| APPL NO | 14/581388 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3415 (20130101) A61B 17/3478 (20130101) Original (OR) Class A61B 2017/00243 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426554 | Siewerdsen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jeffrey H. Siewerdsen (Baltimore, Maryland); Yoshito Otake (Baltimore, Maryland); Russell H. Taylor (Severna Park, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Jeffrey H. Siewerdsen (Baltimore, Maryland); Yoshito Otake (Baltimore, Maryland); Russell H. Taylor (Severna Park, Maryland) |
| ABSTRACT | A tracking and navigation system is provided. The system includes an imaging or treatment device, a tracker device, and a fiducial marker. At least part of the imaging or treatment device is movable relative to a patient. The tracker device is mounted on the imaging or treatment device and is movable therewith relative to the patient. The fiducial marker may be fixed relative to the patient to define a patient coordinate system. The fiducial marker is detectable by the tracker device to substantially maintain registration between the tracker device and the patient coordinate system. A tracking and navigation kit including the tracker device and at least one fiducial marker may also be provided, for example, for retrofitting to existing imaging or treatment devices. |
| FILED | Monday, April 30, 2012 |
| APPL NO | 14/113563 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/4441 (20130101) A61B 34/20 (20160201) Original (OR) Class A61B 2034/2055 (20160201) A61B 2090/376 (20160201) A61B 2090/3983 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2005/1061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426735 | Vegas et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Arturo J. Vegas (Cambridge, Massachusetts); Joshua C. Doloff (Quincy, Massachusetts); Omid Veiseh (Cambridge, Massachusetts); Minglin Ma (Ithaca, New York); Robert S. Langer (Newton, Massachusetts); Daniel G. Anderson (Framingham, Massachusetts) |
| ABSTRACT | Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for coating of any material where reduced fibrosis is desired, such as encapsulated cells for transplantation and medical devices implanted or used in the body. |
| FILED | Monday, August 03, 2015 |
| APPL NO | 14/817084 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/5036 (20130101) Original (OR) Class A61K 35/39 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/085 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/10 (20130101) A61L 33/08 (20130101) A61L 33/08 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) C12N 5/0677 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426745 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Leaf Huang (Durham, North Carolina); Yi Zhao (Chapel Hill, North Carolina); Shutao Guo (Jamaica Plain, Massachusetts); Kai Shi (Chapel Hill, North Carolina) |
| ABSTRACT | Provided herein are polymers comprising Metformin residues (“PolyMet”) as useful therapeutic agents, delivery vehicles and transfection agents for nucleotides. Also provided herein are methods for the treatment of a disease or an unwanted condition in a subject, wherein the methods comprise administering PolyMet as a therapeutic agent to combat the disease or condition. Also provided herein are methods for the treatment of a disease or an unwanted condition in a subject, wherein the methods comprise administering a therapeutic agent in a delivery vehicle that comprises PolyMet. Further provided herein are methods for making PolyMet. |
| FILED | Friday, March 04, 2016 |
| APPL NO | 15/555794 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5123 (20130101) A61K 31/155 (20130101) Original (OR) Class A61K 47/28 (20130101) A61K 47/55 (20170801) A61K 47/61 (20170801) A61K 47/554 (20170801) A61K 47/6911 (20170801) A61K 48/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426757 | Sabatini et al. |
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| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David M. Sabatini (Cambridge, Massachusetts); Omer Yilmaz (Ann Arbor, Michigan); Maria Mihaylova (Somerville, Massachusetts) |
| ABSTRACT | Disclosed herein are novel methods and compositions useful for promoting intestinal stem cell function. The methods and compositions are particularly useful for stimulating the proliferation of and/or self-renewal of intestinal stem cells, as well as for minimizing, preventing, or ameliorating cellular damage resulting from incidental or accidental exposure to radiation (e.g., cancer radiation therapy). |
| FILED | Friday, May 29, 2015 |
| APPL NO | 15/314852 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426772 | Marchant et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jonathan Stephen Marchant (St Paul, Minnesota); John David Chan (St Paul, Minnesota) |
| ABSTRACT | Methods for preventing, inhibiting or treating parasitic flatworm infection in a vertebrate are provided that include administering an effective amount of a composition comprising one or more ergot alkaloids, one or more lysergic acid amides, or one or more dimethoxyisoquinoline derivatives. |
| FILED | Tuesday, May 16, 2017 |
| APPL NO | 15/596776 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Fodder A23K 20/132 (20160501) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/10 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/47 (20130101) A61K 31/48 (20130101) A61K 31/48 (20130101) A61K 31/522 (20130101) A61K 31/4985 (20130101) Original (OR) Class A61K 31/4985 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/423 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426774 | Hahn et al. |
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| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | William C. Hahn (Newton, Massachusetts); Joseph Rosenbluh (Brookline, Massachusetts) |
| ABSTRACT | The present invention provides methods of treating a subject having a Wnt/beta-catenin active cancer by administering to said subject a compound that inhibits the expression or activity of YES1, BIRC5 or BCL2L1, a compound that inhibits YAP1-beta-catenin complex formation, a compound that inhibits YAP1-beta-catenin complex binding to DNA, a compound that inhibits YAP1-beta-catenin-TBX5 complex formation, or any combination thereof. The compound can be, for example, a nucleic acid, a peptide, an antibody or a small molecule. Methods of screening for therapeutic targets for treating cancer are included. |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 14/389310 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 14/47 (20130101) C07K 14/4702 (20130101) C07K 14/4747 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2310/3233 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5017 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426777 | Tran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (Phoenix, Arizona); MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
| ASSIGNEE(S) | The Translational Genomics Research Institute (Phoenix, Arizona); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Nhan Tran (Phoenix, Arizona); Joseph C. Loftus (Scottsdale, Arizona); Harshil Dhruv (Phoenix, Arizona) |
| ABSTRACT | The invention encompasses methods of treating a patient with cancer, such as glioblastoma. The methods may include the administration of one or more pharmaceutical compositions that are capable of inhibiting TROY to treat the patient with cancer. |
| FILED | Thursday, December 14, 2017 |
| APPL NO | 15/842846 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/495 (20130101) A61K 31/495 (20130101) A61K 31/522 (20130101) Original (OR) Class A61K 31/522 (20130101) A61K 31/713 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57411 (20130101) G01N 2800/52 (20130101) G01N 2800/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426786 | Rogawski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Michael A. Rogawski (Sacramento, California); Isaac N. Pessah (Davis, California); Zhengyu Cao (Woodland, California); Pamela J. Lein (Davis, California) |
| ABSTRACT | Provided are compositions comprising a benzodiazepine and a neurosteroid, containing one or both of the benzodiazepine and the neurosteroid in a subtherapeutic dose, and administration of such compositions for mitigation of an epileptic seizure. Further provided are compositions comprising a benzodiazepine, a neurosteroid, and an NMDA blocker, and administration of such compositions for mitigation of an epileptic seizure. |
| FILED | Thursday, July 13, 2017 |
| APPL NO | 15/649460 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/57 (20130101) Original (OR) Class A61K 31/57 (20130101) A61K 31/439 (20130101) A61K 31/439 (20130101) A61K 31/5513 (20130101) A61K 31/5513 (20130101) A61K 31/5517 (20130101) A61K 31/5517 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426797 | Orentas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lentigen Technology, Inc. (Gaithersburg, Maryland); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | LENTIGEN TECHNOLOGY, INC. (Gaithersburg, Maryland); United States of America as Represented by the Secretary, The Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Rimas Orentas (Washington, District of Columbia); Dina Schneider (Potomac, Maryland); Boro Dropulic (Ellicott City, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland) |
| ABSTRACT | Chimeric antigen receptors containing CD33 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed. |
| FILED | Friday, March 23, 2018 |
| APPL NO | 15/934770 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 39/39558 (20130101) A61K 48/0016 (20130101) A61K 2039/505 (20130101) A61K 2039/5152 (20130101) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 16/2803 (20130101) C07K 2317/24 (20130101) C07K 2317/53 (20130101) C07K 2317/62 (20130101) C07K 2317/73 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10426814 — Chemical reprogramming of human glial cells into neurons for brain and spinal cord repair
| US 10426814 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Gong Chen (State College, Pennsylvania); Gang-Yi Wu (State College, Pennsylvania); Lei Zhang (State College, Pennsylvania); Jiu-Chao Yin (State College, Pennsylvania); Hana Yeh (State College, Pennsylvania); Ning-Xin Ma (State College, Pennsylvania); Grace Lee (State College, Pennsylvania) |
| ABSTRACT | Provided are methods and compositions from reprogramming human glial cells into human neurons. The reprogramming is achieved using combinations of compounds that can modify signaling via Transforming growth factor beta (TGF-β), Bone morphogenetic protein (BMP), glycogen synthase kinase 3 (GSK-3), and γ-secretase/Notch pathways. The reprogramming is demonstrated using groups of three or four compounds that are chosen from the group thiazovivin, LDN193189, SB431542, TTNPB, CHIR99021, DAPT, VPA, SAG purmorphamine. Reprogramming is demonstrated using the group of LDN193189/CHIR99021/DAPT, the group of B431542/CHIR99021/DAPT, the group of LDN193189/DAPT/SB431542, the group of LDN193189/CHIR99021/SB431542, a three drug combination of SB431542/CHIR99021/DAPT. Reprogramming using functional analogs of the compounds is also provided, as are pharmaceutical formulations that contain the drug combinations. |
| FILED | Thursday, August 10, 2017 |
| APPL NO | 15/673913 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4439 (20130101) A61K 38/05 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 2501/15 (20130101) C12N 2501/155 (20130101) C12N 2501/727 (20130101) C12N 2501/998 (20130101) C12N 2501/999 (20130101) C12N 2506/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426815 | Lerner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Ethan A. Lerner (Chestnut Hill, Massachusetts); Ehsan Azimi (Boston, Massachusetts); Vemuri B. Reddy (Ashland, Massachusetts) |
| ABSTRACT | Embodiments described herein relates to compositions and methods of preventing and/or treating itch in a subject using a therapeutically effective amount of a MRG receptor antagonist. e.g., a tripeptide QWF. In one embodiment, the itch is a non-histamine mediated itch. |
| FILED | Wednesday, January 20, 2016 |
| APPL NO | 15/543514 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/7038 (20130101) A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 38/06 (20130101) Original (OR) Class A61K 38/06 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426820 | Sen Gupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Anirban Sen Gupta (Cleveland, Ohio); Christa Pawloski (Seven Hills, Ohio) |
| ABSTRACT | A synthetic platelet including a biocompatible flexible nanoparticle, the nanoparticle having an outer surface and a plurality of site targeted peptides conjugated to the surface, the synthetic platelet also including a therapeutic agent, wherein the therapeutic agent is encapsulated by the nanoparticle, wherein the synthetic platelet adheres to the site targeted and promotes delivery of the therapeutic agent onto sites of the synthetic platelet adhesion, and wherein the therapeutic agent is released at the site targeted via a site-relevant enzyme. |
| FILED | Monday, June 25, 2018 |
| APPL NO | 16/017174 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 9/127 (20130101) A61K 9/1271 (20130101) A61K 9/4825 (20130101) A61K 38/00 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 38/177 (20130101) A61K 38/185 (20130101) A61K 38/1774 (20130101) A61K 47/62 (20170801) A61K 47/6911 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 14/78 (20130101) C07K 14/195 (20130101) C07K 14/745 (20130101) C07K 14/70596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426830 | Pavlakis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH (Rockville, Maryland); UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland); UNIVERSITY OF WASHNGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | George Pavlakis (Rockville, Maryland); Barbara Felber (Rockville, Maryland); James Mullins (Seattle, Washington) |
| ABSTRACT | The invention provides methods and compositions for eliciting broad immune responses. The methods employ nucleic acid vaccines that encodes highly conserved elements from a virus. |
| FILED | Friday, August 12, 2016 |
| APPL NO | 15/235430 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/545 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/327 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16222 (20130101) C12N 2740/16234 (20130101) C12N 2740/16271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426831 | Barouch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Dan H. Barouch (Boston, Massachusetts); Bette T. Korber (Los Alamos, New Mexico); William M. Fischer (Los Alamos, New Mexico) |
| ABSTRACT | The invention provides compositions, methods, and kits for the treatment or prevention of viral infections. The polyvalent (e.g., 2-valent) vaccines described herein incorporate computationally-optimized viral polypeptides that can increase the diversity or breadth and depth of cellular immune response in vaccinated subjects. |
| FILED | Monday, April 17, 2017 |
| APPL NO | 15/489220 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 39/235 (20130101) A61K 39/275 (20130101) A61K 2039/53 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2710/24043 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) C12N 2740/16222 (20130101) C12N 2740/16234 (20130101) C12N 2740/16271 (20130101) C12N 2740/16322 (20130101) C12N 2740/16334 (20130101) Technologies for Adaptation to Climate Change Y02A 50/467 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426844 | Agbandje-McKenna et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Mavis Agbandje-McKenna (Gainesville, Florida); William W. Hauswirth (Gainesville, Florida); Arun Srivastava (Gainesville, Florida); Li Zhong (Boxborough, Massachusetts) |
| ABSTRACT | Disclosed are capsid-mutated rAAV vectors and methods for their use in gene therapy, and particularly for use in delivering therapeutic transgenes to treat a variety of mammalian diseases and disorders, including dysfunctions and abnormal conditions of the human eye. VP3 capsid proteins comprising a modification of one or more of the surface-exposed tyrosine residues are disclosed, and in particular, VP3 capsid protein comprising tyrosine-to-phenylalanine mutations at positions corresponding to Y444F, Y500F, and Y730F of the wild-type AAV2 sequence. Also provided are rAAV virions and viral particles that comprise such a mutated AAV capsid protein and a nucleic acid molecule that expresses one or more selected therapeutic or reporter transgenes in one or more mammalian cells of interest. Advantageously, the capsid-mutated rAAV vectors and virions disclosed herein afford improved transduction efficiency in a variety of cells, tissues and organs of interest, when compared to their unmodified (i.e., wild-type) rAAV vector counterparts. |
| FILED | Wednesday, August 24, 2016 |
| APPL NO | 15/246385 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 48/005 (20130101) A61K 48/0058 (20130101) Original (OR) Class Peptides C07K 14/723 (20130101) C07K 14/70571 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/10043 (20130101) C12N 2799/025 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426850 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Michael S. Yu (Timonium, Maryland); Yang Li (Baltimore, Maryland); Daniel Summerfield (Baltimore, Maryland); Allen Yi-Lan Wang (Belle Mead, New Jersey); Catherine A. Foss (Baltimore, Maryland); Martin G. Pomper (Baltimore, Maryland) |
| ABSTRACT | The present invention provides both a caged collagen mimetic peptide (CCMP) having the formula: L-S-Zm-[Gly-X-Y]n-LGly-X-Y-[Gly-X-Y]n (SEQ ID NO: 19); wherein L is one or more detectable moieties; S is one or more spacer molecules; Zm is any amino acid where m is an integer of 1 to 10; X is proline or modified proline; Y is proline or modified proline; Gly is glycine; n is an integer from 1 to 20; and LGly is a glycine covalently linked to a cage moiety comprising a labile protecting group, as well as a collagen mimetic peptides lacking the labile protecting group (CMP). The inventions are useful for binding collagen and denatured collagen and/or gelatin both in vitro and in vivo, and are useful for targeting any organ or tissue where collagen is present, and can be used for research and diagnostic imaging (both in vivo and in vitro) and also for in vivo therapeutic applications. |
| FILED | Friday, November 16, 2012 |
| APPL NO | 13/679431 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/39 (20130101) A61K 49/0056 (20130101) Original (OR) Class Peptides C07K 14/78 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6887 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/55 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426867 | Runge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael Brett Runge (Pine Island, Minnesota); Michael J. Yaszemski (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Michael Brett Runge (Pine Island, Minnesota); Michael J. Yaszemski (Rochester, Minnesota) |
| ABSTRACT | A polycaprolactone fumarate polymer useful as a matrix material for a biocompatible scaffold for tissue engineering applications is disclosed. The polycaprolactone fumarate polymer can be prepared by reacting caprolactone with an alkane polyol to prepare a polycaprolactone precursor, and then reacting the polycaprolactone precursor with fumaric acid or a salt thereof to prepare the polycaprolactone fumarate polymer. The use of an alkane diol, such as 1,2-propanediol, provides a linear polycaprolactone diol precursor. The use of an alkane triol, such as glycerol, provides a branched polycaprolactone triol precursor. The biocompatible polycaprolactone fumarate formulation releases no diethylene glycol or other undesirable byproducts during degradation. |
| FILED | Wednesday, April 04, 2012 |
| APPL NO | 14/009987 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) Original (OR) Class A61L 27/18 (20130101) A61L 27/26 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/08 (20130101) C08G 63/60 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426870 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Christopher S. Chen (Princeton, New Jersey); Jan D. Baranski (Philadelphia, Pennsylvania); Ritika Chaturvedi (Philadelphia, Pennsylvania); Michael T. Yang (West Windsor, New Jersey); Kelly Stevens (Seattle, Washington); Sangeeta Bhatia (Lexington, Massachusetts) |
| ABSTRACT | The present disclosure provides patterned biomaterials having organized cords and extracellular matrix embedded in a 3D scaffold. According, the present disclosure is provides compositions and applications for patterned biomaterials. Pre-patterning of these biomaterials can lead to enhanced integration of these materials into host organisms, providing a strategy for enhancing the viability of engineered tissues by promoting vascularization. |
| FILED | Friday, January 09, 2015 |
| APPL NO | 14/593555 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/44 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/40 (20130101) A61L 27/50 (20130101) Original (OR) Class A61L 27/225 (20130101) A61L 27/507 (20130101) A61L 27/3604 (20130101) A61L 27/3804 (20130101) A61L 27/3808 (20130101) A61L 27/3834 (20130101) A61L 27/3839 (20130101) A61L 27/3886 (20130101) A61L 2430/20 (20130101) A61L 2430/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426872 | Sakamoto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); The United States Of America As Represented By The Department Of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey S. Sakamoto (Ann Arbor, Michigan); Dena Shahriari (Ann Arbor, Michigan); Mark H. Tuszynski (La Jolla, California); Wendy Campana (La Jolla, California); Yacov Koffler (San Diego, California) |
| ABSTRACT | Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall having a thickness of ≤about 100 μm that is formed from a biocompatible and biodegradable material comprising a polyester polymer. The polyester polymer may be polycaprolactone, poly(lactic-co-glycolic acid) polymer, and combinations thereof. The tissue scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. In other aspects, methods of making such tissue scaffolds are provided. Such a method may include mixing a reduced particle size porogen with a polymeric precursor solution. The material is cast onto a template and then can be processed, including assembly in a sheath and removal of the porogen, to form a tissue scaffold having a plurality of porous microchannels. |
| FILED | Friday, October 07, 2016 |
| APPL NO | 15/765981 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) Original (OR) Class A61L 27/58 (20130101) A61L 2300/252 (20130101) A61L 2300/412 (20130101) A61L 2430/32 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 89/00 (20130101) C08L 89/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426949 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Matthew D. Johnson (North Oaks, Minnesota); Edgar Peña (Minneapolis, Minnesota); Simeng Zhang (Minneapolis, Minnesota); Steven Deyo (Apple Valley, Minnesota); YiZi Xiao (Eden Prairie, Minnesota) |
| ABSTRACT | Systems and methods for programming multi-electrode neuromodulation systems, with applications for at least deep brain stimulation (DBS) therapy. One or more configurations can be generated and presented to a user for selection. The selected configurations can be settings for programming a pulse generator. The one or more configurations can be Pareto optimal in terms of one or more objective values and can be generated using a particle swarm optimization. The generated configurations can be visualized on a Pareto front for user selection. Objective values can include minimizing power use, maximizing activation of neural pathways and/or regions of interest, minimizing activation of neural pathways and or regions of avoidance, and maximizing or minimizing the distance to sources of sensed functional data. |
| FILED | Thursday, October 26, 2017 |
| APPL NO | 15/794333 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4064 (20130101) A61B 5/4836 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) Original (OR) Class A61N 1/36082 (20130101) A61N 1/36128 (20130101) A61N 1/37247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427183 | Granger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Michael C. Granger (Salt Lake City, Utah); Jooneon Park (Salt Lake City, Utah); Marc D. Porter (Salt Lake City, Utah) |
| ABSTRACT | Discrete magnetic nanoparticles synthesized using a layer-by-layer technique are disclosed. The nanoparticles contain a magnetic core having a large magnetic moment, a plurality of layers and an exterior coating. The nanoparticles have utility in a wide range of biological and bioanalytical applications. |
| FILED | Friday, January 15, 2016 |
| APPL NO | 14/996383 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/007 (20130101) Original (OR) Class Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) B22F 1/0018 (20130101) B22F 1/025 (20130101) B22F 1/0062 (20130101) B22F 2001/0037 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 25/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 2211/005 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427188 | Oralkan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Omer Oralkan (Morrisvilee, North Carolina); Feysel Yalcin Yamaner (Istanbul, Turkey); Xiao Zhang (Raleigh, North Carolina) |
| ABSTRACT | A capacitive micromachined ultrasonic transducer (CMUT) and methods of forming the same are disclosed herein. In one implementation, the CMUT comprises a glass substrate having a cavity; a patterned metal bottom electrode situated within the cavity of the glass substrate; and a vibrating plate comprising at least a conducting layer, wherein the vibrating plate is anodically bonded to the glass substrate to form an air-tight seal between the vibrating plate and the substrate and wherein a pressure inside the cavity is less than atmospheric pressure (i.e., a vacuum). In another implementation, the CMUT comprises a glass substrate with Through-Glass-Via (TGV) interconnects, wherein a metal electrode is electrically connected to a TGV and wherein said metal electrode can be in the bottom of a cavity of the glass substrate or on the vibrating plate. |
| FILED | Monday, August 01, 2016 |
| APPL NO | 15/225118 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0215 (20130101) B06B 1/0292 (20130101) Original (OR) Class B06B 2201/51 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/047 (20130101) B81B 2201/0271 (20130101) B81B 2201/0292 (20130101) B81B 2207/053 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 3/001 (20130101) B81C 2203/031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427331 | McLane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); VTT Technical Research Centre of Finland Ltd. (Espoo, Finland) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); VTT Technical Research Centre of Finland Ltd. (Espoo, Finland) |
| INVENTOR(S) | Jolie McLane (Newport Beach, California); Michelle Khine (Irvine, California); Ralph Liedert (Irvine, California) |
| ABSTRACT | Disclosed are methods of manufacturing a SH surface including: creating a master with SH features by: depositing a rigid material onto a first surface, wherein the first surface is a shrinkable platform; shrinking the first surface by heating to create a SH surface, wherein the SH surface has micro- and nano-scale structural features that trap air pockets and prevent water from wetting the surface; forming the master by molding an epoxy with the shrunken first surface having a SH surface, wherein the master acquires the SH features of the first surface; and imprinting the SH features of the master onto a second surface to impart the SH features of the master onto the second surface. Some embodiments relate to a superhydrophobic (SH) surface, an article including a SH surface as disclosed, such as a microfluidic device or a food container. |
| FILED | Wednesday, December 09, 2015 |
| APPL NO | 14/964295 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 2200/12 (20130101) B01L 2300/087 (20130101) B01L 2300/123 (20130101) B01L 2300/166 (20130101) B01L 2300/0816 (20130101) B01L 2300/0887 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/3878 (20130101) Original (OR) Class B29C 59/04 (20130101) B29C 2059/023 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2905/00 (20130101) B29K 2905/14 (20130101) B29K 2995/0074 (20130101) B29K 2995/0093 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/712 (20130101) B29L 2031/7148 (20130101) B29L 2031/7532 (20130101) B29L 2031/7562 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/14 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/10 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428025 | Hoekstra et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mycovia Pharmaceuticals, Inc. (Durham, North Carolina); The U.S.A. as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | Mycovia Pharmaceuticals, Inc. (Durham, North Carolina); The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | William J. Hoekstra (Durham, North Carolina); Christopher M. Yates (Raleigh, North Carolina); Mark Behnke (Poolesville, Maryland); Asaf Alimardanov (North Bethesda, Maryland); Scott A. David (Huntsburg, Ohio); Douglas Franklin Fry (Euclid, Ohio) |
| ABSTRACT | The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof. |
| FILED | Wednesday, February 20, 2019 |
| APPL NO | 16/280534 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 213/30 (20130101) C07D 213/38 (20130101) C07D 213/50 (20130101) Original (OR) Class C07D 401/06 (20130101) C07D 405/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428047 | Arancio et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Ottavio Arancio (New York, New York); Daniel Martin Watterson (Douglas, Michigan); Jeffrey Claude Pelletier (Lafayette Hill, Pennsylvania); Saktimayee Mitra Roy (Evanston, Illinois) |
| ABSTRACT | The invention provides for novel MAP kinase inhibitors and compositions comprising the same. In some embodiments, the MAP kinase inhibitors are p38α MAP kinase inhibitors. The invention further provides for methods for treatment of diseases comprising administration of MAP kinase inhibitors or compositions comprising MAP kinase inhibitors. In some embodiments, the disease is Alzheimer's Disease, ALS, Huntington's Disease or Parkinson's Disease. |
| FILED | Thursday, September 07, 2017 |
| APPL NO | 15/697656 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428049 | Herz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Algomedix, Inc. (Mill Creek, Washington) |
| ASSIGNEE(S) | ALGOMEDIX, INC. (Mill Creek, Washington) |
| INVENTOR(S) | Jeffrey M. Herz (Mill Creek, Washington); Edward A. Kesicki (Mill Creek, Washington) |
| ABSTRACT | This disclosure relates to polycyclic heteroaromatic compounds useful as TRPA1 modulators, as well as compositions and methods of treating pain that include the compounds. |
| FILED | Thursday, March 01, 2018 |
| APPL NO | 15/909652 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/46 (20130101) A61K 31/46 (20130101) A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/415 (20130101) A61K 31/415 (20130101) A61K 31/444 (20130101) A61K 31/485 (20130101) A61K 31/485 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/497 (20130101) A61K 31/497 (20130101) A61K 31/498 (20130101) A61K 31/498 (20130101) A61K 31/513 (20130101) A61K 31/513 (20130101) A61K 31/536 (20130101) A61K 31/536 (20130101) A61K 31/537 (20130101) A61K 31/537 (20130101) A61K 31/538 (20130101) A61K 31/538 (20130101) A61K 31/635 (20130101) A61K 31/635 (20130101) A61K 31/4045 (20130101) A61K 31/4045 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 31/4545 (20130101) A61K 31/4545 (20130101) A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 405/14 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) C07D 471/04 (20130101) C07D 471/10 (20130101) C07D 491/107 (20130101) C07D 491/113 (20130101) C07D 495/10 (20130101) C07D 498/04 (20130101) C07D 513/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428060 | Glenn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jeffrey S. Glenn (Palo Alto, California); Michael A. Gelman (New York, New York); Brandon Tavshanjian (San Francisco, California); Kevan Shokat (San Francisco, California); Ingrid Choong (Los Altos, California) |
| ABSTRACT | Compounds and methods are provided for the treatment of pathogen infections. In some embodiments, the anti-infective compounds have broad spectrum activity against a variety of infective diseases, where the diseases are caused by pathogens containing a basic amino acid PIP-2 pincer (BAAPP) domain that interacts with phosphatidylinositol 4,5-bisphosphate (PIP-2) to mediate pathogen replication. Also provided are methods of inhibiting a PI4-kinase and methods of inhibiting viral infection. In some embodiments, the compound is a PI4-kinase inhibiting compound that is a 5-aryl-thiazole or a 5-hetereoaryl-thiazole. The subject compounds may be formulated or provided to a subject in combination with a second anti-infective agent, e.g. interferon, ribivarin, and the like. |
| FILED | Friday, February 09, 2018 |
| APPL NO | 15/892965 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 277/42 (20130101) C07D 277/44 (20130101) C07D 277/46 (20130101) C07D 417/04 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428082 | Janganati et al. |
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| FUNDED BY |
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| APPLICANT(S) | BioVentures, LLC (Little Rock, Arkansas); The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | BioVentures, LLC (Little Rock, Arkansas); The Regents of the University of Colorado, A Body (Denver, Colorado) |
| INVENTOR(S) | Venumadhav Janganati (Little Rock, Arkansas); Peter Crooks (Little Rock, Arkansas); Jessica Ponder (Denver, Colorado); Craig Jordan (Denver, Colorado) |
| ABSTRACT | The present disclosure relates to triazole derivatives of melampomagnolide B, their synthesis, and their use as anti-cancer compounds. |
| FILED | Friday, January 27, 2017 |
| APPL NO | 16/073705 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4192 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 57/15 (20130101) Heterocyclic Compounds C07D 493/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428093 | Schwarz |
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| FUNDED BY |
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| APPLICANT(S) | Richard I. Schwarz (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard I. Schwarz (Oakland, California) |
| ABSTRACT | Herein is described a cell density signaling protein and its tissue-specific lipid cofactor. Constructs, compositions and methods for isolation, purification and use of the protein and the tissue-specific lipid cofactor are described. |
| FILED | Monday, April 25, 2016 |
| APPL NO | 15/137448 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Separation B01D 61/16 (20130101) B01D 61/145 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/572 (20130101) Original (OR) Class Peptides C07K 14/47 (20130101) C07K 14/465 (20130101) C07K 14/4705 (20130101) C07K 16/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428113 | Franco |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Alessandra Franco (San Diego, California) |
| ABSTRACT | In alternative embodiments, provided are compositions, including e.g., isolated, synthetic or recombinant peptides or polypeptides, for: expanding regulatory T cells (Treg) populations; or, for treating, ameliorating, preventing or reversing a vascular inflammation, and Kawasaki disease (KD) or a pediatric acute vasculitis of the coronary arteries, including vascular coronary abnormalities and the same or similar types of acute or chronic vascular inflammatory abnormalities, and methods for making and using them. In one embodiment, provided are immunotherapies for promoting expansion of natural, regulatory T cells to establish, or re-establish, vascular homeostasis; or, for treating, reversing, preventing or ameliorating: a disease or condition associated with an autoimmune disease or condition; an immune-mediated vascular disorder; a disease or condition that is currently treated with intravenous immunoglobulin (IVIG) therapy; a vascular coronary abnormality; an acute or a chronic vasculitis; an autoimmune inflammatory vasculitis; a T cell mediated pediatric vasculitis; Kawasaki disease (KD) or a pediatric acute vasculitis of the coronary arteries; atherosclerosis; rheumatoid arthritis or Juvenile Idiopathic Arthritis; an autoimmune disease or condition; or, a neoplastic hematological disorder such as a lymphoma (e.g., a T cell lymphoma) or a leukemia. |
| FILED | Thursday, June 28, 2018 |
| APPL NO | 16/022306 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/127 (20130101) A61K 38/00 (20130101) A61K 39/0005 (20130101) A61K 39/0008 (20130101) A61K 2039/545 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428115 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Yeon Sun Lee (Tucson, Arizona); Victor J. Hruby (Tucson, Arizona); Frank Porreca (Tucson, Arizona); Josephine Lai (Tucson, Arizona) |
| ABSTRACT | Described are Dynorphin A analog compounds and uses thereof for treating pain in humans and lower animals by administering to a human or lower animal in need of treatment. The compounds interact with the bradykinin receptor to relieve pain. Preferred compounds are amphipathic [Des-Arg7]-dynorphin A peptide analogs and specific cyclic dynorphin A peptide analogs. |
| FILED | Friday, May 23, 2014 |
| APPL NO | 14/893800 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/08 (20130101) C07K 7/64 (20130101) Original (OR) Class C07K 14/665 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428116 | Palmenberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Ann C. Palmenberg (Madison, Wisconsin); Marchel Goldsby Hill (Madison, Wisconsin); Kelly Elizabeth Watters (Madison, Wisconsin); Michael G. Rossman (Madison, Wisconsin); Yue Liu (Madison, Wisconsin) |
| ABSTRACT | A peptide comprising the rhinovirus immunogen peptide of the rhinovirus structural protein 1 (VP1) of rhinovirus C and related vaccines and therapeutic compositions is disclosed. |
| FILED | Wednesday, April 19, 2017 |
| APPL NO | 15/491513 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/125 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 16/1009 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/32722 (20130101) C12N 2770/32734 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428119 | Pastan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Ira H. Pastan (Potomac, Maryland); Ronit Mazor (Rockville, Maryland); Masanori Onda (Rockville, Maryland); Aaron Vassall (Shelton, Washington); Richard Beers (Rockville, Maryland); Jaime Eberle (Delmar, New York); Wenhai Liu (Jamesburg, New Jersey) |
| ABSTRACT | The invention provides a Pseudomonas exotoxin A (PE) comprising an amino acid sequence having a substitution of one or more B-cell and/or T-cell epitopes. The invention further provides related chimeric molecules, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions. Methods of treating or preventing cancer in a mammal, methods of inhibiting the growth of a target cell, methods of producing the PE, and methods of producing the chimeric molecule are further provided by the invention. |
| FILED | Friday, September 01, 2017 |
| APPL NO | 15/693705 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/21 (20130101) Original (OR) Class C07K 16/2896 (20130101) C07K 2319/33 (20130101) C07K 2319/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428124 | Sette et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (San Diego, California) |
| ASSIGNEE(S) | La Jolla Institute For Allergy And Immunology (San Diego, California) |
| INVENTOR(S) | Alessandro Sette (La Jolla, California); Veronique Schulten (San Diego, California); Howard Grey (La Jolla, California); Bjoern Peters (San Diego, California); Jason Greenbaum (San Diego, California) |
| ABSTRACT | The invention relates to Timothy Grass proteins and peptides, subsequences, portions, homologs, variants and derivatives thereof, and methods and uses of Timothy Grass proteins and peptides. Methods include, for example, modulating an immune response; protecting a subject against or treating a subject for an allergic response, allergic disorder or allergic disease; and inducing immunological tolerance to the allergen in a subject. |
| FILED | Thursday, February 07, 2013 |
| APPL NO | 14/375980 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/36 (20130101) A61K 2039/543 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/415 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428133 | Felber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland) |
| INVENTOR(S) | Barbara K. Felber (Rockville, Maryland); George N. Pavlakis (Rockville, Maryland) |
| ABSTRACT | The present invention provides for nucleic acids improved for the expression of interleukin-15 (IL-15) in mammalian cells. The invention further provides for methods of expressing IL-15 in mammalian cells by transfecting the cell with a nucleic acid sequence encoding an improved IL-15 sequence. The present invention further provides expression vectors, and IL-15 and IL-15 receptor alpha combinations (nucleic acid and protein) that increase IL-15 stability and potency in vitro and in vivo. The present methods are useful for the increased bioavailability and biological effects of IL-15 after DNA, RNA or protein administration in a subject (e.g. a mammal, a human). |
| FILED | Monday, October 09, 2017 |
| APPL NO | 15/728455 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/02 (20180101) Peptides C07K 14/535 (20130101) C07K 14/5443 (20130101) Original (OR) Class C07K 14/7155 (20130101) C07K 2319/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428141 | Orentas et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lentigen Technology, Inc. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | LENTIGEN TECHNOLOGY, INC. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Rimas J. Orentas (Seattle, Washington); Dina Schneider (Potomac, Maryland); Boro Dropulic (Ellicott, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland) |
| ABSTRACT | Chimeric antigen receptors containing ROR1 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed. |
| FILED | Friday, November 02, 2018 |
| APPL NO | 16/179364 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1774 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/15 (20130101) C07K 14/7051 (20130101) C07K 14/70514 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70525 (20130101) C07K 14/70532 (20130101) C07K 14/70535 (20130101) C07K 14/70575 (20130101) C07K 14/70589 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) C12N 15/113 (20130101) C12N 2740/16043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428143 | Krummel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Matthew Krummel (San Francisco, California); Miranda Broz (San Francisco, California); Denise Wolf (San Francisco, California); Joshua Pollack (San Francisco, California); Mikhail Biennewies (San Francisco, California) |
| ABSTRACT | Provided herein are methods and compositions for enhancing an immune response and/or for the treatment of an immune-related condition in an individual, e.g., cancer, comprising killing, disabling, or depleting non-stimulatory myeloid cells using an antigen binding protein such as an antibody or antigen binding fragment thereof. |
| FILED | Monday, September 28, 2015 |
| APPL NO | 15/514471 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/30 (20130101) C07K 16/243 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2818 (20130101) C07K 16/2863 (20130101) C07K 16/3046 (20130101) C07K 16/3053 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0626 (20130101) C12N 5/0639 (20130101) C12N 5/0645 (20130101) C12N 5/0693 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428171 | Cheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Jianjun Cheng (Champaign, Illinois); Hanze Ying (Champaign, Illinois) |
| ABSTRACT | The present invention relates to a one-component processing method and system for preparing polyurea materials. This method and system involves a polymerization process using cyclic oligomeric polyurea precursors. These cyclic oligomeric precursors have dynamic urea bonds such as hindered urea bonds (HUBs). These cyclic oligomeric precursors exhibit dynamic properties to reversibly dissociate in situ yielding isocyanate and amine components which polymerize to yield the polyureas, such as linear, branched or cross-linked polyureas. This method and system has advantages over conventional methods that utilize two-component systems. Such two-component systems require the segregation of the isocyanate and amine components to prevent premature or too rapid polymerization. The resulting polyureas are useful for a variety of applications including coatings. |
| FILED | Wednesday, February 03, 2016 |
| APPL NO | 15/547525 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/325 (20130101) C08G 18/757 (20130101) C08G 18/792 (20130101) C08G 18/3228 (20130101) Original (OR) Class C08G 71/02 (20130101) C08G 2150/20 (20130101) Compositions of Macromolecular Compounds C08L 75/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/03 (20130101) C09D 175/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428185 | Bailey et al. |
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| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado); The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado); The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Travis S. Bailey (Fort Collins, Colorado); Chen Guo (Newark, Delaware); Jackson T. Lewis (Fort Collins, Colorado); Kristine Fischenich (Fort Collins, Colorado); Tammy Haut Donahue (Fort Collins, Colorado); Dilanji Wijayasekara (Fort Collins, Colorado); Matthew G. Cowan (Boulder, Colorado); Douglas L. Gin (Longmont, Colorado); Richard D. Noble (Boulder, Colorado) |
| ABSTRACT | Provided herein is a block copolymer hydrogel, comprising a glass formed from a dry blend of polystyrene-poly(ethylene oxide) diblock copolymer (SO) and polystyrene-poly(ethylene oxide)-polystyrene triblock copolymer (SOS) in a molar ratio from between 95:5 and 1:99 SO/SOS and a liquid medium at a concentration between about 32:1 and about 2:1 liquid medium/SO—SOS by weight. The block copolymer hydrogel has a fatigue resistance to at least 500,000 compression cycles. Also provided are methods for forming the hydrogel. |
| FILED | Monday, December 05, 2016 |
| APPL NO | 15/539312 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Separation B01D 69/02 (20130101) B01D 71/28 (20130101) B01D 71/52 (20130101) B01D 71/76 (20130101) B01D 71/80 (20130101) B01D 2325/20 (20130101) B01D 2325/42 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0052 (20130101) B01J 2219/00051 (20130101) B01J 2219/00162 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) Original (OR) Class C08J 2353/00 (20130101) C08J 2453/00 (20130101) Compositions of Macromolecular Compounds C08L 53/00 (20130101) C08L 2207/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1653 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428308 | Keller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Gordon M. Keller (Toronto, Canada); Paul Gadue (New York, New York) |
| ABSTRACT | The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy. The present invention further provides a method of generating hepatocytes, cell populations enriched for hepatocytes, and a method of hepatocyte replacement therapy. |
| FILED | Monday, August 28, 2017 |
| APPL NO | 15/687891 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) Original (OR) Class C12N 5/0603 (20130101) C12N 5/0606 (20130101) C12N 5/0607 (20130101) C12N 2500/90 (20130101) C12N 2501/11 (20130101) C12N 2501/12 (20130101) C12N 2501/16 (20130101) C12N 2501/40 (20130101) C12N 2501/115 (20130101) C12N 2501/148 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2501/415 (20130101) C12N 2506/02 (20130101) C12N 2506/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428313 | Kinney |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Claire Y. H. Kinney (Fort Collins, Colorado) |
| ABSTRACT | Disclosed herein are chimeric flaviviruses including non-coding regions, non-structural proteins, and at least a portion of a C protein from West Nile virus (WNV), and a prM protein and an E protein from Dengue virus (DENV). The DENV may be DEN1 serotype, DEN2 serotype, DEN3 serotype, or DEN4 serotype. Also disclosed herein are compositions and methods for eliciting an immune response in a subject, such as an immune response to one or more DENV serotypes. In particular embodiments, the compositions include one or more inactivated viruses including a WN/DENV chimeric nucleic acid (such as a tetravalent inactivated vaccine including a WN/DEN1 chimera, a WN/DEN2 chimera, a WN/DEN3 chimera, and a WN/DEN4 chimera). The compositions may be administered to a subject to elicit an immune response. |
| FILED | Friday, June 19, 2015 |
| APPL NO | 15/318334 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/70 (20130101) A61K 2039/5252 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2770/24122 (20130101) C12N 2770/24134 (20130101) C12N 2770/24162 (20130101) Technologies for Adaptation to Climate Change Y02A 50/386 (20180101) Y02A 50/394 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428314 | Towner et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Jonathan S. Towner (Decatur, Georgia); Stuart T. Nichol (Atlanta, Georgia); James A. Comer (Decatur, Georgia); Thomas G. Ksiazek (Galveston, Texas); Pierre E. Rollin (Lilburn, Georgia) |
| ABSTRACT | Compositions and methods including and related to the Ebola Bundibugyo virus (EboBun) are provided. Compositions are provided that are operable as immunogens to elicit and immune response or protection from EboBun challenge in a subject such as a primate. Inventive methods are directed to detection and treatment of EboBun infection. |
| FILED | Monday, August 28, 2017 |
| APPL NO | 15/688421 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 2039/53 (20130101) A61K 2039/542 (20130101) A61K 2039/543 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) C07K 16/10 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2760/14121 (20130101) C12N 2760/14134 (20130101) C12N 2760/14143 (20130101) C12N 2760/14145 (20130101) C12N 2810/6072 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428323 | Raines et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ronald T. Raines (Madison, Wisconsin); Kalie Mix (Madison, Wisconsin) |
| ABSTRACT | Methods and reagents for esterification of biological molecules including proteins, polypeptides and peptides. Diazo compounds of formula I: where R is hydrogen, an alkyl, an alkenyl or an alkynyl, RA represents 1-5 substituents on the indicated phenyl ring and RM is an organic group, which includes a label, a cell penetrating group, a cell targeting group, or a reactive group or latent reactive group for reaction to bond to a label, a cell penetrating group, or a cell targeting group, among other organic groups are useful for esterification of biological molecules. Also provided are diazo compounds which are bifunctional and trifunctional coupling reagents as well as reagents for the synthesis of compounds of formula I. |
| FILED | Wednesday, October 11, 2017 |
| APPL NO | 15/730197 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 231/12 (20130101) C07C 231/12 (20130101) C07C 235/34 (20130101) C07C 245/18 (20130101) C07C 269/06 (20130101) C07C 269/06 (20130101) C07C 271/22 (20130101) C07C 319/12 (20130101) C07C 319/12 (20130101) C07C 323/52 (20130101) Heterocyclic Compounds C07D 207/46 (20130101) Peptides C07K 1/13 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428335 | Lindquist et al. |
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| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Susan L. Lindquist (Cambridge, Massachusetts); Aaron D. Gitler (Foster City, California) |
| ABSTRACT | Disclosed are yeast cells expressing TAR DNA-binding protein 43 (TDP-43) and methods of screening yeast cells to identify compounds that prevent or suppress TDP-43-induced toxicity, compounds that inhibit the formation or maintenance of cytoplasmic inclusions of TDP-43, genetic suppressors or enhancers of TDP-43-induced toxicity, and genetic suppressors or enhancers of the formation or maintenance of cytoplasmic inclusions of TDP-43. Compounds identified by such screens can be used to treat or prevent TDP-43 proteinopathies such as frontotemporal lobar degeneration or amyotrophic lateral sclerosis. |
| FILED | Thursday, September 20, 2018 |
| APPL NO | 16/136814 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/81 (20130101) Original (OR) Class C12N 15/1079 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) G01N 33/6896 (20130101) G01N 2500/10 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428384 | Redei |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Eva E. Redei (Chicago, Illinois) |
| ABSTRACT | The present invention relates generally to the detection or diagnosis of post-traumatic stress states in a subject, and provides methods, reagents, and kits useful for this purpose. Provided herein are biomarkers that are indicative of and/or diagnostic of post-traumatic stress states including PTSD. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 15/913511 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428387 | Green et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Michael R. Green (Boylston, Massachusetts); Leyuan Ma (Holden, Massachusetts) |
| ABSTRACT | Methods for treating chronic myeloid leukemia (CML), e.g., BCR-ABL inhibitor imatinib mesylate (IM)-resistant CML, using combination treatments, e.g., combined treatment with a BCR-ABL inhibitor, e.g., IM, and a MEK inhibitor, e.g., trametinib. |
| FILED | Thursday, May 14, 2015 |
| APPL NO | 15/308673 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/519 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57426 (20130101) G01N 2333/91205 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428391 | Guerrero-Preston et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Rafael Guerrero-Preston (Baltimore, Maryland); David Sidransky (Baltimore, Maryland) |
| ABSTRACT | Methods and kits for triaging a human papillomavirus (HPV)-positive woman into colposcopy are disclosed. The methods comprise determining the promoter methylation level of the promoter regions of a group of genes (e.g., viral and host genes) that exhibit increased promoter methylation in women having CIN2+ lesions as compared to women having no intraepithelial lesions or malignancy (NILM). |
| FILED | Wednesday, July 27, 2016 |
| APPL NO | 15/747889 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/303 (20130101) A61B 5/0084 (20130101) A61B 34/10 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1039 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1093 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428392 | Flavell et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Richard Flavell (Guilford, Connecticut); Noah Palm (New Haven, Connecticut); Marcel de Zoete (New Haven, Connecticut) |
| ABSTRACT | The invention relates to the identification of secretory antibody-bound bacteria in the microbiota in a subject that influence the development and progression of inflammatory diseases and disorders. Thus, the invention relates to compositions and methods for detecting and identifying the constituents of a subject's microbiota, methods of modifying the constituents of the microbiota, and methods for treating inflammatory diseases and disorders in a subject in need thereof. |
| FILED | Monday, July 31, 2017 |
| APPL NO | 15/664150 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/741 (20130101) A61K 39/0208 (20130101) A61K 2035/115 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 2537/159 (20130101) C12Q 2563/131 (20130101) C12Q 2565/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429300 | Bosmans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Centre National de la Recherche Scientifique (Paris, France); Aix-Marseilles University (Marseilles, France) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Le Centre National de la Recherche Scientifique (Paris, France); Aix-Marseilles University (Marseilles, France) |
| INVENTOR(S) | Frank Bosmans (Annapolis, Maryland); Pierre E. Bougis (Marseilles, France); Marie-France Eauclaire (Marseilles, France) |
| ABSTRACT | The present invention provides assays utilizing SPR to detect protein-ligand interactions as well as compositions utilized is such assays. |
| FILED | Tuesday, January 26, 2016 |
| APPL NO | 15/545980 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/58 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1205 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/553 (20130101) Original (OR) Class G01N 33/6872 (20130101) G01N 33/54373 (20130101) G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429302 | Nolan et al. |
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| FUNDED BY |
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| APPLICANT(S) | SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH (San Diego, California) |
| ASSIGNEE(S) | Scintillon Institute for Biomedical and Bioenergy Research (San Diego, California) |
| INVENTOR(S) | John P. Nolan (La Jolla, California); Erika Duggan (San Diego, California) |
| ABSTRACT | This technology relates in part to optical methods for analyzing particles, including nanoparticles, thereby determining their presence, identity, origin, size and/or number in a sample of interest. |
| FILED | Wednesday, August 10, 2016 |
| APPL NO | 15/233723 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/06 (20130101) G01N 15/1429 (20130101) G01N 15/1459 (20130101) G01N 21/6428 (20130101) Original (OR) Class G01N 33/542 (20130101) G01N 33/582 (20130101) G01N 33/5308 (20130101) G01N 33/56983 (20130101) G01N 2015/0065 (20130101) G01N 2015/0687 (20130101) G01N 2015/0693 (20130101) G01N 2015/1087 (20130101) G01N 2015/1486 (20130101) G01N 2015/1488 (20130101) G01N 2015/1493 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429361 | Sims et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Carl W. Sims (Santa Rosa, California); Peter W. Carr (St. Paul, Minnesota); Marcelo Roberto Filgueira (Downingtown, Pennsylvania); Klaus Witt (Keltern, Germany) |
| ABSTRACT | A multi-dimensional liquid analysis system includes a flow splitter for separating mobile phase outflow from a first dimension liquid analysis system into first and second liquid split outlet flows. Volumetric flow rate control of the split outlet flows is provided by a flow control pump which withdraws one of the split outlet flows from the flow splitter at a controlled withdrawal flow rate to define the other split outlet flow rate as the difference between the outflow rate from the first dimension system and the withdrawal flow rate. In this manner, accurate and consistent flow division can be accomplished, which is particularly useful for multi-dimensional liquid analysis. |
| FILED | Friday, January 15, 2016 |
| APPL NO | 14/996784 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/10 (20130101) G01N 30/32 (20130101) G01N 30/463 (20130101) Original (OR) Class G01N 30/465 (20130101) G01N 30/7233 (20130101) G01N 2030/324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429376 | Soper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steven A. Soper (Baton Rouge, Louisiana); Michael C. Murphy (Baton Rouge, Louisiana); June Feng (Shreveport, Louisiana); Robin L. McCarley (Prairieville, Louisiana); André A. Adams (Burke, Virginia) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| INVENTOR(S) | Steven A. Soper (Baton Rouge, Louisiana); Michael C. Murphy (Baton Rouge, Louisiana); June Feng (Shreveport, Louisiana); Robin L. McCarley (Prairieville, Louisiana); André A. Adams (Burke, Virginia) |
| ABSTRACT | Microdevices are disclosed to efficiently, accurately, and rapidly isolate and enumerate rare cells, such as circulating tumor cells, from liquids such as whole blood. The system employs multiple parallel meandering channels having a width on the order of 1-2 cell diameters. The microdevices can be produced at low-cost, may readily be automated, and in many instances may be used without pre-processing of the sample. They may be used to isolate and enumerate rare cells, including for example the detection and diagnosis of cancers, cancer staging, or evaluating the effectiveness of a therapeutic intervention, or detecting pathogenic bacteria. The device may optionally be used to nondestructively capture and later to release target cells. |
| FILED | Wednesday, May 13, 2009 |
| APPL NO | 12/992225 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0883 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 15/1484 (20130101) G01N 33/49 (20130101) Original (OR) Class G01N 33/4915 (20130101) G01N 2015/1006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429379 | Steere et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Allen C. Steere (Wellesley, Massachusetts); Elise E. Drouin (Boston, Massachusetts) |
| ABSTRACT | Disclosed herein are methods of diagnosing Rheumatoid arthritis in a subject comprising determining whether the subject is immunologically reactive with N-acetylglucosamine-6-sulfatase and/or filamin-A, wherein immunological reactivity of the subject to one or more of N-acetylglucosamine-6-sulfatase or filamin-A, as compared to an appropriate control, indicates the subject has rheumatoid arthritis. Examples of specific assays and kits for use with the methods are also disclosed. |
| FILED | Thursday, May 12, 2016 |
| APPL NO | 15/571734 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/505 (20130101) Original (OR) Class G01N 33/564 (20130101) G01N 33/6866 (20130101) G01N 33/56972 (20130101) G01N 2333/47 (20130101) G01N 2333/57 (20130101) G01N 2333/914 (20130101) G01N 2333/4706 (20130101) G01N 2800/24 (20130101) G01N 2800/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429384 | Spiegelman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bruce M. Spiegelman (Waban, Massachusetts); Jang Hyun Choi (Brookline, Massachusetts); Shingo Kajimura (Boston, Massachusetts); Alexander Banks (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Bruce M. Spiegelman (Waban, Massachusetts); Jang Hyun Choi (Brookline, Massachusetts); Shingo Kajimura (Boston, Massachusetts); Alexander Banks (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides methods and compositions for selectively promoting anti-metabolic disorder activity over classical PPAR gamma activation through modulation of PPAR gamma phosphorylation (e.g., Ser-273 phosphorylation of murine peroxisome proliferator activated receptor gamma (PPAR gamma) 2 or a corresponding serine residue in a murine PPAR gamma 2 homolog, including a human). Also provided are methods for preventing, treating, or predictiving responsiveness of therapies for metabolic disorders in a subject through selective inhibition of such PPAR gamma phosphorylation. Further provided are methods for identifying compounds that are capable of modulating such PPAR gamma phosphorylation. |
| FILED | Thursday, January 20, 2011 |
| APPL NO | 13/522736 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/70567 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) Original (OR) Class G01N 2333/70567 (20130101) G01N 2440/14 (20130101) G01N 2500/04 (20130101) G01N 2800/04 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429386 | Fritz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Heather Fritz (Davis, California); Patricia Conrad (Davis, California) |
| ABSTRACT | The present disclosure provides antibodies that bind the surface of Toxoplasma gondii oocysts, methods for using such antibodies and kits and devices for practicing such methods. Such antibodies, methods, kits and devices find use in detection of T. gondii oocysts and the isolation of such oocysts from samples including environmental samples, food-based samples, diagnostic samples, and the like. |
| FILED | Tuesday, March 08, 2016 |
| APPL NO | 15/548062 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/20 (20130101) C07K 2317/33 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56905 (20130101) Original (OR) Class G01N 2333/45 (20130101) G01N 2469/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429397 | Pflum |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WAYNE STATE UNIVERSITY (Detroit, Michigan) |
| ASSIGNEE(S) | WAYNE STATE UNIVERSITY (Detroit, Michigan) |
| INVENTOR(S) | Mary Kay Pflum (Northville, Michigan) |
| ABSTRACT | A cell permeable ATP analog has the following formula: or a physiologically acceptable salt thereof, wherein: R0 is n, o, p are each independently 1, 2, 3, 4, 5, or 6, m is 0, 1, 2, 3, 4, or 5; X is O, S, NH, or CH2. R1 is H or C1-6 alkyl, R2 is H, C1-6 alkyl, C6-30 aryl, C5-32 heteroaryl, or C7-32 alkylaryl; R3, R4 are each independently H, C1-6 alkyl, C6-30 aryl, C5-32 heteroaryl, or C7-32 alkylaryl, wherein R3, and R4 can be combined together to form a ring structure. |
| FILED | Monday, June 20, 2016 |
| APPL NO | 15/187206 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/20 (20130101) Polysaccharides; Derivatives Thereof C08B 37/003 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/82 (20130101) Original (OR) Class G01N 33/581 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429473 | Dyvorne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Hadrien Dyvorne (Branford, Connecticut); Priti Balchandani (New York, New York) |
| ABSTRACT | A method, magnetic resonance imaging computing device, and a non-transitory computer readable medium for producing a slice-selective adiabatic magnetization T2 preparation pulse for magnetic resonance imaging. A pulse control signal including an adiabatic half passage pulse control signal, an adiabatic full passage pulse control signal, and a reverse adiabatic half passage pulse control signal is generated. A plurality of slice-selective linear phase subpulse control signals are generated. The pulse control signal is sampled using the plurality of slice-selective linear phase subpulse control signals to generate a slice-selective adiabatic magnetization T2 preparation control signal. The slice-selective adiabatic magnetization T2 preparation control signal is output to a waveform generator to produce the slice-selective adiabatic magnetization T2 preparation pulse. |
| FILED | Friday, March 11, 2016 |
| APPL NO | 15/067507 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/485 (20130101) G01R 33/4833 (20130101) G01R 33/5602 (20130101) Original (OR) Class G01R 33/56341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10430933 | Sobieranski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Bringham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Antonio Carlos Sobieranski (Florianopolis, Brazil); Utkan Demirci (Stanford, California); Huseyin Cumhur Tekin (Bursa, Turkey); Fatih Inci (Palo Alto, California) |
| ABSTRACT | Method and system for lensless, shadow optical imaging. Formation of a hologram shadow image having higher spatial resolution and lower noise level is accomplished by processing image information contained in multiple individual hologram shadow image frames acquired either under conditions of relative shift between point light source and the detector of the system or under stationary conditions, when system remains fixed in space and is devoid of any relative movement during the process of acquisition of individual image frames. |
| FILED | Thursday, February 25, 2016 |
| APPL NO | 15/553630 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/265 (20130101) G03H 1/0443 (20130101) G03H 1/0866 (20130101) G03H 2001/0447 (20130101) G03H 2001/0825 (20130101) G03H 2001/2655 (20130101) G03H 2222/15 (20130101) G03H 2226/11 (20130101) G03H 2227/03 (20130101) G03H 2240/56 (20130101) Image Data Processing or Generation, in General G06T 5/50 (20130101) Original (OR) Class G06T 2207/20056 (20130101) G06T 2207/20221 (20130101) Pictorial Communication, e.g Television H04N 5/23232 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10430955 | Frise et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Erwin Frise (Oakland, California); Benjamin Booth (San Lorenzo, California); Charles McParland (Berkeley, California); Keith Beattie (Oakland, California); Bill Fisher (Berkeley, California); Ann S. Hammonds (Berkeley, California); Susan E. Celniker (Lafayette, California) |
| ABSTRACT | Disclosed herein are systems methods for high content screening for microscope imaging. In some embodiments, the system comprises: a microscope; and a processor configured to implement: a slide loader module; a reference imager module; a slide imager module; a region of interest (ROI) finder module; a compare imager module; a calibrator module; and an image stitcher module. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 15/692552 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/33 (20170101) G06T 7/168 (20170101) G06T 7/337 (20170101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/10056 (20130101) G06T 2207/10148 (20130101) G06T 2207/10152 (20130101) G06T 2207/20056 (20130101) G06T 2207/20061 (20130101) G06T 2207/20221 (20130101) G06T 2207/30024 (20130101) Pictorial Communication, e.g Television H04N 5/23229 (20130101) H04N 5/23293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431342 | Kovatchev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Boris P. Kovatchev (Charlottesville, Virginia); Marc D. Breton (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Boris P. Kovatchev (Charlottesville, Virginia); Marc D. Breton (Charlottesville, Virginia) |
| ABSTRACT | A method, system and related computer program product for tracking the probability of hypoglycemia from routine self-monitoring of blood glucose (SMBG) data in patients with diabetes. A specific bivariate probability distribution of low BG events based jointly on the Low BG Index (LBGI) and the Average Daily Risk Range (ADRR) is used to predict hypoglycemia probability of occurrence from inputted SMBG data. The SMBG data is retrieved from a series of SMBG data of a patient available from the patient's glucose meter and allows tracking of the probability for future hypoglycemia over a predetermined duration, e.g., a 24 or 48 hour period. The tracking includes presentation of visual and/or numerical output, as we construction of hypoglycemia risk trajectories that would enable warning messages for crossing of predefined thresholds, such as 50% likelihood for upcoming hypoglycemia below 50 mg/dl. |
| FILED | Thursday, September 02, 2010 |
| APPL NO | 13/394091 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/042 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10432871 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hui Cao (New Haven, Connecticut); Brandon Redding (New Haven, Connecticut); Michael Choma (Hamden, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Hui Cao (New Haven, Connecticut); Brandon Redding (New Haven, Connecticut); Michael Choma (Hamden, Connecticut) |
| ABSTRACT | Systems and methods are provided for imaging using complex lasers. In general, a complex laser may be used as an electromagnetic source for an imaging application. The use of a lower spatial coherence configured complex laser in imaging applications may advantageously mitigate coherent artifacts in imaging such as cross-talk and speckle and improve overall image quality. Imaging applications where a complex laser may be useful include both incoherent imaging applications, such as digital light projectors and traditional microscopy, and coherent imaging applications, such as optical coherence tomography (OCT) and holography. The systems and methods provided also enable controlling the degree of spatial coherence of a complex laser. |
| FILED | Monday, April 16, 2012 |
| APPL NO | 14/110937 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/48 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/10 (20130101) H01S 3/30 (20130101) H01S 3/213 (20130101) H01S 3/0804 (20130101) H01S 5/10 (20130101) H01S 5/041 (20130101) Pictorial Communication, e.g Television H04N 5/235 (20130101) Original (OR) Class H04N 9/3161 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10426390 | Berthier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tasso, Inc. (Seattle, Washington) |
| ASSIGNEE(S) | Tasso, Inc. (Seattle, Washington) |
| INVENTOR(S) | Erwin Berthier (Seattle, Washington); Ben Casavant (Seattle, Washington); Ben Moga (Soquel, California) |
| ABSTRACT | The disclosed apparatus, systems and methods relate to devices, systems and methods for the collection of bodily fluids involving a single-use actuation and retraction mechanism disposed within a collector. |
| FILED | Wednesday, December 21, 2016 |
| APPL NO | 15/387177 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/15113 (20130101) A61B 5/15115 (20130101) Original (OR) Class A61B 5/15117 (20130101) A61B 5/15144 (20130101) A61B 5/150022 (20130101) A61B 5/150099 (20130101) A61B 5/150167 (20130101) A61B 5/150175 (20130101) A61B 5/150221 (20130101) A61B 5/150236 (20130101) A61B 5/150916 (20130101) A61B 5/150984 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426548 | Tearney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Guillermo J. Tearney (Cambridge, Massachusetts); Milen Shishkov (Watertown, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts); Benjamin J. Vakoc (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The General Hosppital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Guillermo J. Tearney (Cambridge, Massachusetts); Milen Shishkov (Watertown, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts); Benjamin J. Vakoc (Cambridge, Massachusetts) |
| ABSTRACT | According one exemplary embodiment of the present invention, method and system can be provided for applying a laser radiation to at least one portion of a biological structure. For example, a beam of the laser radiation can be provided to the portion, whereas a cross-sectional area of the beam is at most about 1/10th of an entire area of the at least one portion. The beam can be applied to the portion (a) based on a predetermined pattern, (b) while modulating a wavelength of the laser radiation, and/or (c) while monitoring a depth of the application of the laser radiation. |
| FILED | Thursday, February 01, 2007 |
| APPL NO | 11/670043 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 18/24 (20130101) Original (OR) Class A61B 2017/00066 (20130101) A61B 2017/22051 (20130101) A61B 2018/2272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426638 | Evans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| ASSIGNEE(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| INVENTOR(S) | Christopher O. Evans (Amherst, New Hampshire); Keith D. Violette (Sandown, New Hampshire) |
| ABSTRACT | A system for powering a prosthetic arm is disclosed. The system includes at least one internal battery located in the prosthetic arm, at least one external battery connected to the prosthetic arm, and a master controller configured to connect either the at least one internal battery or the at least one external battery to a power bus to power the prosthetic arm. |
| FILED | Wednesday, February 08, 2017 |
| APPL NO | 15/427306 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) A61F 2/68 (20130101) A61F 2/70 (20130101) Original (OR) Class A61F 2/78 (20130101) A61F 2/581 (20130101) A61F 2/582 (20130101) A61F 2/585 (20130101) A61F 2/586 (20130101) A61F 2002/587 (20130101) A61F 2002/701 (20130101) A61F 2002/702 (20130101) A61F 2002/704 (20130101) A61F 2002/705 (20130101) A61F 2002/708 (20130101) A61F 2002/747 (20130101) A61F 2002/764 (20130101) A61F 2002/768 (20130101) A61F 2002/769 (20130101) A61F 2002/5001 (20130101) A61F 2002/5061 (20130101) A61F 2002/5083 (20130101) A61F 2002/6836 (20130101) A61F 2002/6845 (20130101) A61F 2002/6881 (20130101) A61F 2002/7625 (20130101) A61F 2002/7635 (20130101) A61F 2002/7645 (20130101) A61F 2002/7665 (20130101) A61F 2002/7862 (20130101) A61F 2002/30464 (20130101) A61F 2220/0075 (20130101) A61F 2250/008 (20130101) A61F 2250/0074 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 19/005 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 9/06 (20130101) F16D 27/01 (20130101) F16D 41/12 (20130101) F16D 41/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426735 | Vegas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Arturo J. Vegas (Cambridge, Massachusetts); Joshua C. Doloff (Quincy, Massachusetts); Omid Veiseh (Cambridge, Massachusetts); Minglin Ma (Ithaca, New York); Robert S. Langer (Newton, Massachusetts); Daniel G. Anderson (Framingham, Massachusetts) |
| ABSTRACT | Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for coating of any material where reduced fibrosis is desired, such as encapsulated cells for transplantation and medical devices implanted or used in the body. |
| FILED | Monday, August 03, 2015 |
| APPL NO | 14/817084 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/5036 (20130101) Original (OR) Class A61K 35/39 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/085 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/10 (20130101) A61L 33/08 (20130101) A61L 33/08 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) C12N 5/0677 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426867 | Runge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael Brett Runge (Pine Island, Minnesota); Michael J. Yaszemski (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Michael Brett Runge (Pine Island, Minnesota); Michael J. Yaszemski (Rochester, Minnesota) |
| ABSTRACT | A polycaprolactone fumarate polymer useful as a matrix material for a biocompatible scaffold for tissue engineering applications is disclosed. The polycaprolactone fumarate polymer can be prepared by reacting caprolactone with an alkane polyol to prepare a polycaprolactone precursor, and then reacting the polycaprolactone precursor with fumaric acid or a salt thereof to prepare the polycaprolactone fumarate polymer. The use of an alkane diol, such as 1,2-propanediol, provides a linear polycaprolactone diol precursor. The use of an alkane triol, such as glycerol, provides a branched polycaprolactone triol precursor. The biocompatible polycaprolactone fumarate formulation releases no diethylene glycol or other undesirable byproducts during degradation. |
| FILED | Wednesday, April 04, 2012 |
| APPL NO | 14/009987 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) Original (OR) Class A61L 27/18 (20130101) A61L 27/26 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/08 (20130101) C08G 63/60 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427134 | DeCoste et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army Edgewood Chemical Biological Center (APG, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jared B. DeCoste (Bel Air, Maryland); Trenton M. Tovar (Parkville, Maryland); Ivan O. Iordanov (Baltimore, Maryland) |
| ABSTRACT | A composite adsorbent material includes a component that creates a localized electric field and a porous material where adsorption occurs, wherein the localized electric field extends into the porous material. The localized electric field created by the component controls adsorption properties of the porous material. The porous material may be microporous. The component may include ferroelectric material including a β-phase of polyvinylidene fluoride (PVDF), and wherein the porous material may include any of zeolites, silicas, activated carbons, covalent organic frameworks (COFs), polymers of intrinsic microporosity (PIMs), and metal-organic frameworks (MOFs). The MOFs may include any of HKUST-1, UiO-66, and UiO-66-NH2. The β-phase of PVDF and the HKUST-1 may be electrospun together. The β-phase of PVDF includes aligned polymer chains that create the localized electric field extending within the porous material. The localized electric field enhances adsorption of an adsorbate, particularly a non-polar adsorbate such as oxygen or dioxide, to the porous material. |
| FILED | Tuesday, December 20, 2016 |
| APPL NO | 15/385300 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/04 (20130101) B01D 2253/25 (20130101) B01D 2253/202 (20130101) B01D 2253/204 (20130101) B01D 2257/104 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/18 (20130101) B01J 20/20 (20130101) B01J 20/26 (20130101) B01J 20/103 (20130101) B01J 20/226 (20130101) B01J 20/28011 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427188 | Oralkan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Omer Oralkan (Morrisvilee, North Carolina); Feysel Yalcin Yamaner (Istanbul, Turkey); Xiao Zhang (Raleigh, North Carolina) |
| ABSTRACT | A capacitive micromachined ultrasonic transducer (CMUT) and methods of forming the same are disclosed herein. In one implementation, the CMUT comprises a glass substrate having a cavity; a patterned metal bottom electrode situated within the cavity of the glass substrate; and a vibrating plate comprising at least a conducting layer, wherein the vibrating plate is anodically bonded to the glass substrate to form an air-tight seal between the vibrating plate and the substrate and wherein a pressure inside the cavity is less than atmospheric pressure (i.e., a vacuum). In another implementation, the CMUT comprises a glass substrate with Through-Glass-Via (TGV) interconnects, wherein a metal electrode is electrically connected to a TGV and wherein said metal electrode can be in the bottom of a cavity of the glass substrate or on the vibrating plate. |
| FILED | Monday, August 01, 2016 |
| APPL NO | 15/225118 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0215 (20130101) B06B 1/0292 (20130101) Original (OR) Class B06B 2201/51 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/047 (20130101) B81B 2201/0271 (20130101) B81B 2201/0292 (20130101) B81B 2207/053 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 3/001 (20130101) B81C 2203/031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427195 | Ball |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OXYTEC LLC (Newton, Massachusetts) |
| ASSIGNEE(S) | OXYTEC LLC (Newton, Massachusetts) |
| INVENTOR(S) | Raymond G. Ball (Newton, Massachusetts) |
| ABSTRACT | A method and system for the reduction of contamination in soil and groundwater is provided. Cyclic oligosaccharides can be used, for example, to carry oxidants, carry activators, solubilize organic contaminants and promote biodegradation. |
| FILED | Wednesday, November 07, 2018 |
| APPL NO | 16/183327 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/24 (20130101) Reclamation of Contaminated Soil B09C 1/002 (20130101) B09C 1/02 (20130101) B09C 1/08 (20130101) Original (OR) Class B09C 2101/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/72 (20130101) C02F 1/78 (20130101) C02F 1/725 (20130101) C02F 2101/38 (20130101) C02F 2101/306 (20130101) C02F 2101/322 (20130101) C02F 2101/327 (20130101) C02F 2101/363 (20130101) C02F 2101/366 (20130101) C02F 2103/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427293 | Asbeck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Prisident and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Alan Thomas Asbeck (Waltham, Massachusetts); Ignacio Galiana Bujanda (Cambridge, Massachusetts); Ye Ding (Cambridge, Massachusetts); Robert Joseph Dyer (Concord, Massachusetts); Arnar Freyr Larusson (Hanover, New Hampshire); Brendan Thomas Quinlivan (Rutland, Massachusetts); Kai Schmidt (Berlin, Germany); Diana Wagner (Charlotte, North Carolina); Conor J. Walsh (Cambridge, Massachusetts); Michael Wehner (Berkeley, California) |
| ABSTRACT | In at least one aspect, there is provided a system for generating force about one or more joints including a soft exosuit having a plurality of anchor elements and at least one connection element disposed between the plurality of anchor elements. The system also includes at least one sensor to determine a force the at least one connection element or at least one of the plurality of anchor elements and to output signals relating to the force, at least one actuator configured to change a tension in the soft exosuit and at least one controller configured to receive the signals output from the at least one sensor and actuate the at least one actuator responsive to the received signals. |
| FILED | Tuesday, March 17, 2015 |
| APPL NO | 14/660704 |
| ART UNIT | 3652 — Material and Article Handling |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/024 (20130101) A61H 1/0244 (20130101) A61H 1/0266 (20130101) A61H 3/00 (20130101) A61H 2201/149 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/501 (20130101) A61H 2201/1215 (20130101) A61H 2201/1238 (20130101) A61H 2201/1246 (20130101) A61H 2201/1261 (20130101) A61H 2201/1481 (20130101) A61H 2201/1628 (20130101) A61H 2201/1652 (20130101) A61H 2201/1664 (20130101) A61H 2201/1671 (20130101) A61H 2201/5002 (20130101) A61H 2201/5007 (20130101) A61H 2201/5061 (20130101) A61H 2201/5064 (20130101) A61H 2201/5069 (20130101) A61H 2201/5079 (20130101) A61H 2201/5084 (20130101) A61H 2201/5097 (20130101) A61H 2230/60 (20130101) A61H 2230/605 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427367 | Ghebrebrhan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Michael Ghebrebrhan (Cambridge, Massachusetts); Landa Hoke (Leominster, Massachusetts) |
| ABSTRACT | Disclosed is a retro-reflective thread 100 including an internal section 10; a plurality of fibers 12, each fiber comprising a respective longitudinal axis and a respective surface and each fiber comprising a first material that is at least partially optically transmissive, and wherein said plurality of fibers are configured with their respective longitudinal axes substantially co-linearly aligned with one another and said plurality of fibers are interconnected in series around said internal section and wherein a first part 12b of said respective surface of each of said plurality of fibers faces into said internal section; and a reflective material 14 provided on said first part of said respective surface of each of said plurality of fibers. |
| FILED | Wednesday, February 24, 2016 |
| APPL NO | 15/051966 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/01 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00605 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/12 (20130101) B29K 2033/04 (20130101) B29K 2995/003 (20130101) B29K 2995/0026 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427725 | Banerjee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEXGEN COMPOSITES LLC (Franklin, Ohio) |
| ASSIGNEE(S) | NEXGEN COMPOSITES LLC (Kettering, Ohio) |
| INVENTOR(S) | Robin Banerjee (Centerville, Ohio); Michael S. Sheppard (Centerville, Ohio) |
| ABSTRACT | A unitary floor system comprising a top layer, a bottom layer, and, and an intermediate layer including a longitudinal central floor axis. Further, the intermediate layer comprises floor components that define at least one edge line, wherein the floor components are tiled together and sandwiched between the top layer and the bottom layer to provide an integral structure that comprises a continuous surface, unitary floor and a frame that surrounds the floor components. Each of the floor components comprises a composite assembly of a first set of material strips and a second set of material strips. The first set of material strips has a different density compared to the second set of material strips, and edge lines of the floor components span between the longitudinal central floor axis and the frame, wherein the floor components do not cross the longitudinal central floor axis. |
| FILED | Monday, February 12, 2018 |
| APPL NO | 15/894264 |
| ART UNIT | 3612 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/18 (20130101) B32B 5/18 (20130101) B32B 5/26 (20130101) B32B 5/142 (20130101) B32B 5/245 (20130101) B32B 7/12 (20130101) B32B 15/14 (20130101) B32B 15/20 (20130101) B32B 21/10 (20130101) B32B 27/12 (20130101) B32B 37/12 (20130101) B32B 2250/03 (20130101) B32B 2250/20 (20130101) B32B 2250/40 (20130101) B32B 2260/023 (20130101) B32B 2260/046 (20130101) B32B 2262/101 (20130101) B32B 2307/722 (20130101) B32B 2419/04 (20130101) B32B 2605/00 (20130101) Motor Vehicles; Trailers B62D 25/2054 (20130101) B62D 29/00 (20130101) B62D 33/02 (20130101) B62D 33/04 (20130101) Original (OR) Class Finishing Work on Buildings, e.g Stairs, Floors E04F 15/102 (20130101) E04F 15/107 (20130101) E04F 15/02038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427788 | Grenga |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Todd M. Grenga (Cumberland, Rhode Island) |
| ABSTRACT | An airdrop platform is provided that includes a pallet. Under the pallet are a first outrigger main body and a second outrigger main body. The first outrigger main body and second main body each include at least one outrigger finger. When airdropped, the outrigger main bodies and outrigger fingers are configured to move from under the pallet. |
| FILED | Thursday, November 17, 2016 |
| APPL NO | 15/353793 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/10 (20130101) B64D 1/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427806 | Chao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Chia-Chun Chao (Rolling Hills Estates, California); Victor Shiaw-Jong Lin (Oak Park, California); Siegfried W. Janson (Redondo Beach, California) |
| ABSTRACT | A control algorithm that determines one or more deviations in an orbit of a companion satellite, and control the companion satellite to minimize effects of perturbing forces. |
| FILED | Friday, May 12, 2017 |
| APPL NO | 15/593798 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/10 (20130101) B64G 1/24 (20130101) B64G 1/40 (20130101) B64G 1/242 (20130101) Original (OR) Class B64G 1/405 (20130101) B64G 1/1085 (20130101) B64G 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427934 | Coutu, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Ronald A Coutu, Jr. (Milwaukee, Wisconsin); Robert S LaFleur (Fairborn, Ohio); John P. K. Walton (Troy, Ohio); LaVern A Starman (Dayton, Ohio) |
| ABSTRACT | A cooling structure for a heat source, where the cooling structure includes a beam having a first end and a second end and a length disposed therebetween. The beam is formed at least in part of a first material having a first thermal coefficient of expansion and a second material having a second thermal coefficient of expansion, where the first thermal coefficient of expansion is different from the second thermal coefficient of expansion. The first end of the beam is thermally connected to the heat source, such that heat generated by the heat source is conducted along the length of the beam to the second end of the beam. The heat conducted through the beam causes the beam to deflect as the first and second materials expand differently due to the difference in the first and second thermal coefficients of expansion. |
| FILED | Friday, July 28, 2017 |
| APPL NO | 15/662810 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/007 (20130101) B81B 7/0087 (20130101) Original (OR) Class B81B 2201/032 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428037 | Stenger-Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John D. Stenger-Smith (Ridgecrest, California); Paul A. Goodman (Pleasant Prairie, Wisconsin) |
| ABSTRACT | Methods of synthesizing and purifying ethers are described. The synthesis and purification are achieved using an etherification technique followed by one or two fractional distillations. The etherification utilizes an element having low work function properties. Examples of low work function elements include, but are not limited to, metals or their hydrides, such as sodium, lithium or potassium or some combination thereof. This technique yields ethers of greater than 90% purity. |
| FILED | Thursday, October 26, 2017 |
| APPL NO | 15/794508 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 307/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428175 | Palmese et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania); The United States of America as represented by the Secretary of the Army (Washington, District of Columbia); Giuseppe R. Palmese (Hainesport, New Jersey); Fengshuo Hu (Mason, Ohio); Xing Geng (Fort Wayne, Indiana); John J. La Scala (Wilmington, Delaware) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania); The United States of America Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Giuseppe R. Palmese (Hainesport, New Jersey); Fengshuo Hu (Mason, Ohio); Xing Geng (Fort Wayne, Indiana); John J. La Scala (Wilmington, Delaware) |
| ABSTRACT | Grafted triglycerides comprising a triglyceride grafted with a fatty acid residue containing 4 to 30 carbon atoms are reacted with an epoxide resin and an amine curing agent to yield an epoxy thermoset. The grafted triglyceride is prepared by reaction of an epoxidized triglyceride with a fatty acid. By varying the length of the fatty residue, the number of fatty residues per triglyceride, the identity of the epoxy resin and the amine curing agent, it is possible to prepare epoxy thermosets that exhibit superior physical properties compared to the properties of epoxy thermosets prepared without the grafted triglyceride, or as compared to epoxy thermosets wherein the epoxidized triglyceride is used in place of the grafted triglyceride. |
| FILED | Friday, September 11, 2015 |
| APPL NO | 15/507532 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/06 (20130101) C08G 59/20 (20130101) C08G 59/50 (20130101) C08G 59/145 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/00 (20130101) C08K 3/013 (20180101) C08K 3/013 (20180101) Compositions of Macromolecular Compounds C08L 63/00 (20130101) C08L 63/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 163/00 (20130101) Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom C11C 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428225 | Mahn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SWIMC LLC (Cleveland, Ohio) |
| ASSIGNEE(S) | SWIMC LLC (Cleveland, Ohio) |
| INVENTOR(S) | Edmund J. Mahn (Grove City, Ohio); Mark E. Walker (Tinley Park, Illinois); Mark J. Wytiaz (Chicago, Illinois) |
| ABSTRACT | A powder coating composition comprising: (a) a first acrylic powder resin having a hydroxyl value of at least about 180; (b) a second acrylic powder resin having a hydroxyl value between about 45 and about 80; (c) a crosslinker reactive with the hydroxyl functional acrylic resins; and (d) an acicular filler. |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 13/798329 |
| ART UNIT | 1768 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/035 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428234 | Tabor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Christopher E. Tabor (Kettering, Ohio); Michael F. Durstock (West Chester, Ohio); James R. Deneault (Kettering, Ohio) |
| ABSTRACT | A method for forming a conductive trace on a substrate. A metallic liquid is mixed with a solvent to produce a metallic liquid mixture. The metallic liquid mixture is stimulated to produce a colloidal suspension of discrete metallic liquid particles surrounded by the solvent. The colloidal suspension is aerosolized with a carrier gas, and passed through a nozzle to deposit the discrete metallic liquid particles onto the substrate. The deposited discrete metallic liquid particles are annealed, thereby producing the conductive trace. The conductive trace has a substantially contiguous core of the metallic liquid within a substantially non-electrically conductive solid skin that substantially bounds the liquid core. |
| FILED | Monday, September 25, 2017 |
| APPL NO | 15/713955 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/0012 (20130101) B05B 7/262 (20130101) B05B 7/0416 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/52 (20130101) Original (OR) Class C09D 11/322 (20130101) Alloys C22C 28/00 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/125 (20130101) H05K 2203/1344 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428659 | Hagan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Benjamin F. Hagan (Winston-Salem, North Carolina); Matthew A. Devore (Rocky Hill, Connecticut); Dominic J. Mongillo (West Hartford, Connecticut); Ryan Alan Waite (Glastonbury, Connecticut) |
| ABSTRACT | A flowpath component for a gas turbine engine includes a leading edge, a trailing edge connected to the leading edge via a first surface and a second surface, an impingement cavity internal to the flowpath component, the impingement cavity being aligned with one of the leading edge and the trailing edge, a cooling passage extending at least partially through the flowpath component, and a plurality of crossover holes connecting the cooling passage to the impingement cavity. At least one of the crossover holes is aligned normal to an expected direction of fluid flow through the cooling passage and is unaligned with an axial line drawn perpendicular to a stacking line of the flowpath component. |
| FILED | Monday, December 21, 2015 |
| APPL NO | 14/976041 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) Original (OR) Class F01D 9/041 (20130101) F01D 9/065 (20130101) F01D 25/12 (20130101) F01D 25/24 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/35 (20130101) F05D 2240/121 (20130101) F05D 2240/303 (20130101) F05D 2250/232 (20130101) F05D 2250/323 (20130101) F05D 2260/201 (20130101) F05D 2260/202 (20130101) F05D 2260/205 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428665 | Tracey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Bradford Alan Tracey (Cold Spring, Kentucky); Thomas Lipinski (Monroe, Ohio); Donald George LaChapelle (West Chester, Ohio); Michael Murrish (Norwood, Ohio) |
| ABSTRACT | A clamping assembly includes a shaft, a first plurality of clamps, and a second plurality of clamps. Each of the first and the second pluralities of clamps includes a first wall, a second wall extending outwardly from the first wall in a first direction, and a third wall extending outwardly from the first wall in a second direction. Each of the first plurality of clamps is longitudinally spaced apart by one of the second plurality of clamps. The second walls of the first plurality of clamps are transversely spaced apart from the second walls of the second plurality of clamps. The first and the second walls of the first and the second pluralities of clamps collectively define a first slot that receives the shaft. The first and the third walls of the first and the second pluralities of clamps collectively define a second slot for receiving adjacent components. |
| FILED | Friday, December 11, 2015 |
| APPL NO | 14/966268 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) Original (OR) Class F01D 9/042 (20130101) F01D 25/246 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/60 (20130101) F05D 2230/64 (20130101) F05D 2240/35 (20130101) F05D 2240/128 (20130101) F05D 2260/30 (20130101) F05D 2260/36 (20130101) F05D 2260/39 (20130101) F05D 2300/10 (20130101) F05D 2300/6033 (20130101) F05D 2300/50212 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428672 | Peters |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Christopher J. Peters (West Hartford, Connecticut) |
| ABSTRACT | Aspects of the disclosure are directed to a seal comprising: a shoe, and at least two beams coupled to the shoe, where a first width associated with the beams exceeds a second width associated with the shoe in a reference direction. Aspects of the disclosure are directed to an engine comprising: a compressor section, a turbine section, and a floating, non-contact seal that includes: a shoe, and at least two beams coupled to the shoe, where the beams extend past an edge of a flowpath surface associated with the shoe in a reference direction. |
| FILED | Monday, February 08, 2016 |
| APPL NO | 15/018374 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 9/02 (20130101) F01D 11/025 (20130101) Original (OR) Class Non-positive-displacement Pumps F04D 29/164 (20130101) F04D 29/526 (20130101) Pistons; Cylinders; Sealings F16J 15/442 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428690 | Juh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Christopher M. Juh (South Windsor, Connecticut); David J. Wasserman (Hamden, Connecticut) |
| ABSTRACT | A variable positioner includes a body portion with a cylindrical component, and an axially aligned through hole in the body position. A threading protrudes radially inward from an inner surface of the axially aligned through hole. A first axial end of the variable positioner defines an interface surface for interfacing with a rotor arm. |
| FILED | Monday, February 02, 2015 |
| APPL NO | 14/611369 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/025 (20130101) F01D 5/026 (20130101) F01D 25/16 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/107 (20130101) F02C 7/36 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/52 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/671 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49238 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428736 | Hannwacker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | David Andrew Hannwacker (Torrance, California); Stephen John Howell (West Newbury, Massachusetts) |
| ABSTRACT | A combustor assembly for a gas turbine engine includes a combustor dome defining an opening, a cooling hole, and at least in part defining a combustion chamber. The combustor dome includes a first side and a second side, the cooling hole extending from the first side to the second side. The combustor assembly additionally includes a fuel-air injector hardware assembly positioned at least partially within the opening of the combustor dome and including a heat shield. The heat shield includes a heat deflector lip. The cooling hole in the combustor dome is oriented to direct a cooling airflow onto the heat deflector lip to maintain at least a portion of the heat shield within a desired operating temperature range. |
| FILED | Thursday, February 25, 2016 |
| APPL NO | 15/053541 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) Original (OR) Class Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/02 (20130101) F23R 3/04 (20130101) F23R 3/283 (20130101) F23R 2900/03044 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428823 | Del Donno et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, None) |
| INVENTOR(S) | Andrew Mark Del Donno (Lynn, Massachusetts); Justin Anthony Black (Lynn, Massachusetts) |
| ABSTRACT | A compressor has an axial portion and a centrifugal portion. A disk structure is provided to support the centrifugal portion and is connected to the centrifugal portion with a rabbet joint. |
| FILED | Wednesday, October 21, 2015 |
| APPL NO | 14/918622 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/025 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/08 (20130101) Non-positive-displacement Pumps F04D 17/025 (20130101) F04D 19/02 (20130101) Original (OR) Class F04D 29/266 (20130101) F04D 29/285 (20130101) F04D 29/624 (20130101) F04D 29/644 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428842 | Hutchison et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| ASSIGNEE(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| INVENTOR(S) | Matthew G. Hutchison (Manassas, Virginia); William Bosworth (Manassas, Virginia); Andrew Kehlenbeck (Manassas, Virginia); Devin Jensen (Manassas, Virginia) |
| ABSTRACT | A triplex pneumatic architecture system is disclosed having first, second, and third pneumatic subsystems where triplex redundancy may be accomplished by measuring only one particular node in each system, such as a measured current of the servo valve. Each of the first, second, and third pneumatic subsystems are configured to control a separate redundant pneumatic actuation assembly. Each subsystem may comprise a current sensor to measure a control current from a servo driver to a servo valve that controls the pneumatic actuation assembly to output a measured current value, and a dump valve coupled to a relay. Each processor is configured to generate a termination signal to actuate the first relay to open the first dump valve. The triplex pneumatic architecture system further includes a communication bus to communicatively couple each of the first, second, and third pneumatic subsystems. Each processor is configured to generate the termination signal and to communicate the termination signal to one or more of the relays when one measured current value deviates from the two other measured current values by a predetermined error value. |
| FILED | Friday, May 05, 2017 |
| APPL NO | 15/588178 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 13/42 (20130101) B64C 13/48 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 9/09 (20130101) Original (OR) Class F15B 13/02 (20130101) F15B 13/16 (20130101) F15B 18/00 (20130101) F15B 19/005 (20130101) F15B 20/00 (20130101) F15B 21/044 (20130101) F15B 21/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428971 | DeFelice |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Robert DeFelice (South Windsor, Connecticut) |
| ABSTRACT | A valve assembly includes a flow duct with an inlet and an outlet downstream from the inlet. A piston housing is inside the flow duct and is axially aligned with a center axis of the flow duct. A piston is inside the piston housing and is configured to extend downstream of the piston housing in a closed position. A control chamber is between the piston and an upstream end of the piston housing. A control opening extends through the upstream end of the piston housing and fluidically communicates with the flow duct and the control chamber. A cap extends through the control opening. A cap passage extends through the cap and has an inlet outside of the piston housing and an outlet inside the piston housing, and includes two ninety-degree turns between the inlet and the outlet of the cap passage. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 15/913005 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 1/126 (20130101) F16K 17/10 (20130101) F16K 31/1221 (20130101) Original (OR) Class F16K 31/1223 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/3421 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429070 | Hannwacker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | David Andrew Hannwacker (Torrance, California); Stephen John Howell (West Newbury, Massachusetts) |
| ABSTRACT | A combustor assembly for a gas turbine engine includes a combustor dome and a combustion chamber liner formed integrally of a ceramic matrix composite material. The combustor dome defines a plurality of openings for receiving a respective plurality of fuel air injector hardware assemblies and may extend continuously along a circumferential direction. |
| FILED | Thursday, February 25, 2016 |
| APPL NO | 15/053369 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/06 (20130101) F23R 3/007 (20130101) Original (OR) Class F23R 3/10 (20130101) F23R 3/50 (20130101) F23R 3/60 (20130101) F23R 2900/03042 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429159 | Dylla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Joseph P. Dylla (Oro Valley, Arizona); Michael J. Scolman (Oro Valley, Arizona) |
| ABSTRACT | A deployable airfoil airborne body such as missiles, bombs, guided projectiles, MALDs and UAVs includes first and second rigid airfoil sections stowed end-to-end along the airborne body. The airfoil sections have first and second interior edges of equal lengths, abutting ends connected at the first and second interior edges by a free-floating pivot, a distant end of the first rigid airfoil section coupled to a fixed pivot on the airborne body, and a distant end of the second rigid airfoil section having a translation point. The first and second rigid airfoil sections are configured to rotate in opposite directions to move the translation point axially along the airborne body to abut the fixed pivot driving the free-floating pivot radially away from the airborne body to join the first and second interior edges in a deployed position transverse to the airborne body to form a rigid airfoil. |
| FILED | Tuesday, June 27, 2017 |
| APPL NO | 15/634530 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/102 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429171 | Vyacheslav |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF MISSISSIPPI (University, Mississippi) |
| ASSIGNEE(S) | THE UNIVERSITY OF MISSISSIPPI (University, Mississippi) |
| INVENTOR(S) | Aranchuk Vyacheslav (University, Mississippi) |
| ABSTRACT | A sensor for a vibration imaging system is provided. The sensor includes a transmitter configured to project an array of laser beams onto a surface of an object such that neighboring beams in the array of laser beams are frequency shifted relative to each other, an interferometer configured to mix radiations reflected from neighboring points on the surface of the object such that the radiations from neighboring points interfere with one another, a photodetector array configured to produce output signals representative of the interfering beams, a demodulator configured to demodulate the output signals, and a computing device configured to calculate a deformation profile for the object based on the demodulated output signals. |
| FILED | Thursday, July 21, 2016 |
| APPL NO | 15/745771 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02003 (20130101) G01B 9/02019 (20130101) G01B 9/02027 (20130101) G01B 9/02028 (20130101) G01B 9/02045 (20130101) G01B 9/02077 (20130101) G01B 9/02083 (20130101) Original (OR) Class G01B 11/161 (20130101) G01B 2290/65 (20130101) G01B 2290/70 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/004 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 7/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429187 | Sanders et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Glen A. Sanders (Scottsdale, Arizona); Lee K. Strandjord (Tonka Bay, Minnesota); Neil A. Krueger (Saint Paul, Minnesota); Edward Summers (Glendale, Arizona); Clarence Eugene Laskoskie (Scottsdale, Arizona) |
| ABSTRACT | A method comprises: receiving a first optical signal and a second optical signal; injecting a portion of the first optical signal into an optical resonator; injecting a portion of the second optical signal into the optical resonator, where the first optical signal and the second optical signal propagate in opposite directions in the optical resonator; emitting a portion of the first optical signal; emitting a portion of the second optical signal; coupling, by free space optics, a portion of the emitted first optical signal to a first power detector; coupling, by free space optics, a portion of the emitted second optical signal to a second power detector; adjusting the power level of the received first optical signal based upon a first detected power level detected by the first power detector; and adjusting the power level of the received second optical signal based upon a second detected power level detected by the second power detector. |
| FILED | Tuesday, September 04, 2018 |
| APPL NO | 16/121317 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429241 | Mitchell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas A. Mitchell (Northampton, Pennsylvania) |
| ASSIGNEE(S) | Wavefront Research, Inc. (Northampton, Pennsylvania) |
| INVENTOR(S) | Thomas A. Mitchell (Northampton, Pennsylvania) |
| ABSTRACT | An imaging optical system including a plurality of imaging optical sub-systems, each having at least one optical element and receiving light from a source, and a plurality of spectrometer optical sub-systems, each spectrometer optical sub-system receiving light from at least one of the imaging optical sub-systems, each imaging optical sub-system and spectrometer optical sub-system combination having a spatial distortion characteristic, each spatial distortion characteristic having a predetermined relationship to the other spatial distortion characteristics. |
| FILED | Monday, July 02, 2018 |
| APPL NO | 16/025233 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/14 (20130101) G01J 3/28 (20130101) G01J 3/36 (20130101) G01J 3/0208 (20130101) G01J 3/2823 (20130101) Original (OR) Class G01J 2003/2826 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429258 | Bartyczak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Susan L. Bartyczak (King George, Virginia); Willis Mock, Jr. (Fredericksburg, Virginia); Lauren N. Edgerton (Milford, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Susan L. Bartyczak (King George, Virginia); Willis Mock, Jr. (Fredericksburg, Virginia); Lauren N. Edgerton (Milford, Virginia) |
| ABSTRACT | A test fixture is provided for evaluating structural response of a sample to blast pressure from a muzzle of a gas gun. The fixture includes an adapter, an annular flange, a gauge assembly and a target assembly. The adapter has a proximal rim and an expansion tube. The rim attaches to the muzzle to direct the blast pressure into the tube towards an exit opposite the rim. The annular flange has a ring and a shim that attaches to the tube at the exit. The gauge assembly contains the sample between upstream and downstream stress gauges. The target assembly contains the gauge assembly. The target assembly includes front and rear annular plates connecting coaxially in parallel. The rear annular plate connects to the ring. The tube carries the blast pressure through the exit to strike the gauge assembly for the stress gauges to measure stress from the blast pressure. The ring includes first circumferentially distributed through-holes substantially parallel to the flange's symmetry axis and second circumferentially distributed mutually parallel through-holes angularly offset from the symmetry axis for mounting the rear plate to the ring either coaxially or at an oblique angle. |
| FILED | Tuesday, September 12, 2017 |
| APPL NO | 15/701774 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/08 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/2218 (20130101) G01L 7/043 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2203/0066 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/665 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429405 | Savchenko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arthur Savchenko (Morristown, New Jersey); Fred Petri (Snohomish, Washington) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Arthur Savchenko (Morristown, New Jersey); Fred Petri (Snohomish, Washington) |
| ABSTRACT | Systems and methods for improving common mode cancelation in a vibrating beam accelerometer (VBA) by using multiple resonant modes. The VBA includes two double-ended tuning forks (DETF). Additional oscillators drive the DETFs into the extra resonant modes. This increases common mode rejection from two modes to four modes. In addition the scale factor of the additional mode may provide a greater scale factor than prior designs. |
| FILED | Friday, February 03, 2012 |
| APPL NO | 13/365574 |
| ART UNIT | 2865 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/097 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429433 | Robertazzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Raphael P. Robertazzi (Ossining, New York); Peilin Song (Lagrangeville, New York); Franco Stellari (Waldwick, New Jersey) |
| ABSTRACT | A method for characterizing an integrated circuit that includes ramping the supply voltage to an integrated circuit as a function of time for each of the transistors in the integrated circuit, and measuring a power supply current for the integrated circuit during the ramping of the power supply voltage. The measured peaks in the power supply current are a current pulse that identifies an operation state in which each of the transistors are in an on state. The peaks in the power supply current are compared to the reference peaks for the power supply current for a reference circuit having a same functionality as the integrated circuit to determine the integrated circuit's fitness. |
| FILED | Thursday, November 17, 2016 |
| APPL NO | 15/354095 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/275 (20130101) G01R 31/311 (20130101) G01R 31/2607 (20130101) G01R 31/2621 (20130101) G01R 31/2642 (20130101) Original (OR) Class G01R 31/2855 (20130101) G01R 31/3004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429488 | Parks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Walter J. Keller, III (Bridgeville, Pennsylvania); Jennting Timothy Hsu (Bethel Park, Pennsylvania) |
| ASSIGNEE(S) | NOKOMIS, INC. (Charleroi, Pennsylvania) |
| INVENTOR(S) | Brandon Scott Parks (South Park, Pennsylvania); Walter J. Keller, III (Bridgeville, Pennsylvania); Jennting Timothy Hsu (Bethel Park, Pennsylvania) |
| ABSTRACT | A system for identifying a real-world geographic location of an emission source emitting electromagnetic energy includes a platform configured for movement and an apparatus disposed on the platform and configured to collect and process, in a passive manner and during movement of the platform, at least a pair of successive samples of the electromagnetic energy emission and define angular and spatial coordinates of the emission source. The apparatus includes at least a pair of antennas, a receiver coupled to antennas and a processor executing a predetermined logic. |
| FILED | Monday, May 22, 2017 |
| APPL NO | 15/601391 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/46 (20130101) G01S 5/04 (20130101) Original (OR) Class G01S 5/0221 (20130101) G01S 5/0278 (20130101) G01S 5/0284 (20130101) G01S 5/0294 (20130101) G01S 19/21 (20130101) G01S 19/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429491 | Ray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois); HRL LABORATORIES, LLC (Malibu, California) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois); HRL LABORATORIES, LLC (Malibu, California) |
| INVENTOR(S) | Gary Alan Ray (Issaquah, Washington); Peter Petre (Oak Park, California); Charles E. Martin (Thousand Okas, California); Shankar R. Rao (Agoura Hills, California) |
| ABSTRACT | A method for generating pulse descriptor words (PDWs) including frequency and/or bandwidth data from time-varying signals received by a sensor includes filtering, at a plurality of blind source separation (BSS) modules, signals derived from the time-varying signals, each BSS module including a filtering subsystem having a plurality of filter modules. Each filter module has a frequency filter coefficient (α) and is parameterized by a center frequency (f). The method also includes transmitting at least one blind source separated signal from the BSS modules to a PDW generation module communicatively coupled to the filtering subsystem. The method further includes generating, using the PDW generation module and based on the blind source separated signal, at least one PDW parameter vector signal containing the frequency data. The method also includes updating, upon generating and based on the PDW parameter vector signal, values of α and/or f for each filter module. |
| FILED | Monday, September 12, 2016 |
| APPL NO | 15/262987 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 23/155 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/006 (20130101) G01S 7/021 (20130101) G01S 7/2923 (20130101) Original (OR) Class G01S 13/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429538 | Venezia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William A. Venezia (Stuart, Florida); John J. Holmes (Columbia, Maryland); Eric S. Dykes (Loxahatchee, Florida) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | William A. Venezia (Stuart, Florida); John J. Holmes (Columbia, Maryland); Eric S. Dykes (Loxahatchee, Florida) |
| ABSTRACT | According to exemplary inventive practice, an ADCP system (including one or more acoustic Doppler current profilers) and a magnetometer system (including one or more magnetometers) are placed underwater. The ADCP system is used to obtain ADCP time series data. The magnetometer system is used to obtain magnetometer time series data. A computer performs computations with respect to input from the ADCP system and input from the magnetometer system. The computations include formulation of a least squares matrix to minimize a least squared error between the ADCP time series data and the magnetometer time series data. The present invention may be practiced, for instance, whereby a magnetometer is centrally located in relation to a triangular arrangement of three ADCPs, or whereby the ADCP system and the magnetometer system are co-located. |
| FILED | Wednesday, July 06, 2016 |
| APPL NO | 15/203593 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/38 (20130101) Original (OR) Class G01V 3/081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429546 | Ulmer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intellisense Systems, Inc. (Torrance, California) |
| ASSIGNEE(S) | INTELLISENSE SYSTEMS, INC. (Torrance, California) |
| INVENTOR(S) | Christopher T. Ulmer (San Pedro, California) |
| ABSTRACT | An assembly and method for using ultrasonic wind sensors and their assembly with solar cell technology is disclosed. The weather sensor assembly may include a sensor module with a top sensor and a bottom sensor, where the top sensor and the bottom sensor are separated by a gap to allow air to flow through unobstructed. By including an unobstructed gap in the sensor module structure, ultrasonic signals communicated by the ultrasonic wind sensors to obtain wind measurements are less subject to comprise from signal interference, thereby improving accuracy. Additionally, one or more power modules may be included that provide power storage and power generation capabilities, which are then placed beneath the sensor module. By doing so, multiple power modules can be stacked vertically on top of one another to ensure that ultrasonic wind sensors, which typically require high power, are powered more efficiently. |
| FILED | Friday, December 23, 2016 |
| APPL NO | 15/390196 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/245 (20130101) G01P 13/00 (20130101) Meteorology G01W 1/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429588 | Yoo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sung-Joo Ben Yoo (Davis, California); Kuanping Shang (Davis, California); Yu Zhang (Woodland, California) |
| ABSTRACT | The disclosed embodiments relate to the design of an optical phased array grating. This optical phased array grating includes an optical waveguide comprising a first material having a uniform lateral width, wherein the first material confines the optical waveguide as the optical waveguide core. It also includes an overlay layer comprising a sequence of overlays made of a second material spaced across a top surface of the optical waveguide, wherein successive overlays in the sequence have continuously varying longitudinal duty cycles and continuously varying lateral widths between an input end and an output end of the overlay layer, and wherein the second material has a lower optical index than the first material. The optical phased array grating also includes a cladding layer comprised of a third material deposited over the overlay layer and the optical waveguide. |
| FILED | Friday, October 26, 2018 |
| APPL NO | 16/172527 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/29301 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429648 | Sverdrup |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Sverdrup (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lawrence Sverdrup (San Diego, California) |
| ABSTRACT | An augmented reality head worn device having a a curve transparent mirror, a scanning light source defining a field of view, a holographic optical element adapted to provide pupil expansion to create an eye-box, and at least one projection system for providing high acuity at or near a center of the field of view. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/257883 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/289 (20130101) G02B 27/0081 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 2027/013 (20130101) G02B 2027/0112 (20130101) G02B 2027/0174 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429677 | Puckett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Matthew Wade Puckett (Scottsdale, Arizona); Mary K. Salit (Plymouth, Minnesota) |
| ABSTRACT | An embodiment of a waveguide has a Brillouin bandwidth, and includes cladding and a core. The cladding includes first layers of a first material, each first layer having a physical characteristic of approximately a first value, and includes second layers of a second material, each second layer having the physical characteristic of approximately a second value, the second layers alternating with the first layers such that the Brillouin bandwidth is wider than the Brillouin bandwidth would be if the cladding excluded the first layers or excluded the second layers. For example, the first and second cladding layers can be formed from different materials, or can be formed having different values of a physical characteristic such as thickness, acoustic velocity, or index of refraction. Such a waveguide can facilitate alignment of the waveguide's optical bandwidth with the waveguide's Brillouin bandwidth because the Brillouin bandwidth is widened compared to conventional waveguides. |
| FILED | Wednesday, June 28, 2017 |
| APPL NO | 15/636474 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/721 (20130101) Optical Elements, Systems, or Apparatus G02B 6/036 (20130101) G02B 6/122 (20130101) G02B 6/132 (20130101) G02B 6/136 (20130101) G02B 2006/12176 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/125 (20130101) Original (OR) Class G02F 2201/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429718 | Pant et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Mihir Pant (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts); Mikkel Heuck (Cambridge, Massachusetts) |
| ABSTRACT | A photon source to deliver single photons includes a storage ring resonator to receive pump photons and generate a signal photon and an idler photon. An idler resonator is coupled to the storage resonator to couple the idler photon out of the storage resonator and into a detector. Detection of the idler photon stops the pump photons from entering the storage resonator. A signal resonator is coupled to the storage resonator to couple out the signal photon remaining in the storage resonator and delivers the signal photon to applications. The photon source can be fabricated into a photonic integrated circuit to achieve high compactness, reliability, and controllability. |
| FILED | Tuesday, October 24, 2017 |
| APPL NO | 15/792066 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/31 (20130101) Original (OR) Class G02F 1/39 (20130101) G02F 1/3501 (20130101) G02F 1/3536 (20130101) G02F 2001/3503 (20130101) Transmission H04B 10/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10430265 | Larsen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Per Larsen (Irvine, California); Stefan Brunthaler (Irvine, California); Michael Franz (Irvine, California) |
| ABSTRACT | Error report reporting errors that occur during software execution may be normalized to account for diversification of single software program. A method for useful providing error reports comprises receiving information regarding computer system status at a time of failure of proper execution of a diversified implementation of a computer program, the computer program having a plurality of diversified implementations; and transforming the information regarding the computer system status using metadata indicative of differences between the diversified implementation of the computer program and a canonical implementation of the computer program. |
| FILED | Thursday, October 01, 2015 |
| APPL NO | 15/514811 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/0706 (20130101) G06F 11/0775 (20130101) Original (OR) Class G06F 21/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10430598 | Roy |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Radhika Roy (Howell, New Jersey) |
| ABSTRACT | Various embodiments are described that relate to a generalized Bloom filter design methodology. The Bloom filter design methodology can be used for preventing Bloom filter-specific cyber-attacks instead of designing special-purpose Bloom filters that can be applied preventing a specific kind of attack for a given kind of communications networking environment. The resultant security functionalities that can be considered as a package for the generalized secure Bloom filter can include Identifier Modifications, Secure Indexes, Dynamic Salting, Independent Multiple Hash Functions, Random Bit Insertions, Fake Bit Injections, Secure Record Linkage, Single Bloom Filter with all Identifiers, and Encryption. The overall secure generalized Bloom filter algorithms can be devised along with numerous sub-algorithms for these functionalities for making the Bloom-filter-based communications over a network providing robust security, reliability, and availability, preventing known cyber-attacks. |
| FILED | Thursday, June 08, 2017 |
| APPL NO | 15/617161 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/6209 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0643 (20130101) H04L 9/3218 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10430700 | Valdes Garcia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Alberto Valdes Garcia (Chappaqua, New York); Dirk Pfeiffer (Croton on Hudson, New York); Fengnian Xia (Plainsboro, New Jersey) |
| ABSTRACT | A system for labeling an object uses at least one object label made from a material that absorbs and reflects incident energy uniformly across all wavelengths of incident energy at a ratio proportional to a thickness of the material and that includes a pattern having variations in the thickness of the material along at least one of two orthogonal directions across the label. An interrogator directs a predetermined wavelength of radiation to the at least one label, and a reader to receives reflected radiation from the label at the predetermined wavelength and interprets the reflected radiation to recognize the pattern. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/118975 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) C23C 16/56 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10430954 | Menozzi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
| INVENTOR(S) | Alberico Menozzi (Raleigh, North Carolina) |
| ABSTRACT | The described technology regards an augmented reality system and method for estimating a position of a location of interest relative to the position and orientation of a display, including receiving and selectively filtering a plurality of measurement vectors from a rate-gyroscope. Systems of the described technology include including a plurality of sensors, a processing module or other computation means, and a database. Methods of the described technology use data from the sensor package useful to accurately render graphical user interface information on a display. |
| FILED | Thursday, September 14, 2017 |
| APPL NO | 15/704962 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/165 (20130101) Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) G02B 27/0093 (20130101) G02B 2027/0138 (20130101) G02B 2027/0141 (20130101) G02B 2027/0181 (20130101) Electric Digital Data Processing G06F 1/163 (20130101) G06F 3/01 (20130101) G06F 3/011 (20130101) G06F 3/04817 (20130101) G06F 11/00 (20130101) Image Data Processing or Generation, in General G06T 5/20 (20130101) G06T 7/33 (20170101) Original (OR) Class G06T 11/00 (20130101) G06T 19/006 (20130101) G06T 2200/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10430961 | Qian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ObjectVideo Labs, LLC (Tysons, Virginia) |
| ASSIGNEE(S) | ObjectVideo Labs, LLC (Tysons, Virginia) |
| INVENTOR(S) | Gang Qian (McLean, Virginia); Yunxian Zhou (Herndon, Virginia); David Conger (Sterling, Virginia); Allison Beach (Leesburg, Virginia) |
| ABSTRACT | Methods and apparatus are disclosed for enhancing urban surface model with image data obtained from a satellite image. Three dimensional models of an urban cityscape obtained from digital surface models may comprise surface location information but lack image information associated with the cityscape, such as the color and texture of building facades. The location of the satellite at the time of recording the satellite image interest may be obtained from metadata associated with the satellite image. A 3D model of a cityscape corresponding to the satellite image may be subjected to a transformation operation to determine portions of the 3D model that are viewable from a location corresponding to the location of the satellite when taking the picture. Visible facades buildings of the 3D model may be identified and mapped to portions of the satellite image which may then be used in rendering 2D images from the 3D model. |
| FILED | Friday, December 16, 2016 |
| APPL NO | 15/382521 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/60 (20130101) Original (OR) Class G06T 15/04 (20130101) G06T 17/05 (20130101) G06T 2207/10032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431106 | Tolland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aptima, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | APTIMA, INC. (Woburn, Massachusetts) |
| INVENTOR(S) | Michael Tolland (Woburn, Massachusetts); Zachary Zuzack (Waltham, Massachusetts) |
| ABSTRACT | A performance measurement system is provided utilizing an architecture configured to efficiently merge and monitor different types of performance data. Connectors are provided to receive and translate different types of performance data from different sources. The performance data is translated into and stored in a common data model format. In some embodiments, key attributes are defined for each of the performance data sources that uniquely characterizes each relevant performance data so that is can be parsed into separate processing streams to increase system performance. The key attributes also act as cues to organize the performance data as it is being merged so that it can be accessed without requiring a specific source data linkage. Using model listeners, determinations can be quickly made regarding when performance data is changed to reduce calculations necessary to determine measure values. Some embodiments merge different types of performance data in real-time. |
| FILED | Wednesday, April 13, 2016 |
| APPL NO | 15/098216 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04842 (20130101) G06F 3/04847 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431393 | Bag et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Santanu Bag (West Chester, Ohio); James R. Deneault (Dayton, Ohio); Michael F. Durstock (West Chester, Ohio) |
| ABSTRACT | A method for aerosol-jet printing a layered perovskite structure by applying a PEDOT:PSS layer to a substrate; applying a layer of lead iodide (PbI2) to the PEDOT:PSS layer; and applying an aerosol mist of methylammonium iodide (CH3NH3I) atop the PbI2 layer with an aerosol-jet nozzle to form a CH3NH3PbI3 perovskite film layer. The substrate may be an ITO glass substrate, and the PEDOT:PSS layer may be applied by a process selected from spin-coating, inkjet-printing, slot-die-coating, aerosol-jet printing, physical vapor deposition, chemical vapor deposition, and electrochemical deposition. The PbI2 layer may be applied by a process selected from spin-coating, aerosol-jet printing, inkjet-printing, slot-die-coating, physical vapor deposition, chemical vapor deposition, and electrochemical deposition, and the PbI2 for application to the PEDOT:PSS layer may be in a solution of DMF, DMSO, γ-butyrolactone, or a combination thereof. |
| FILED | Tuesday, February 06, 2018 |
| APPL NO | 15/889806 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/20 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0007 (20130101) H01L 51/0013 (20130101) H01L 51/0028 (20130101) H01L 51/0037 (20130101) H01L 51/0096 (20130101) H01L 51/424 (20130101) H01L 51/4293 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431412 | Akinwande et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Akintunde I. Akinwande (Newton, Massachusetts); Stephen Angelo Guerrera (Waitsfield, Vermont) |
| ABSTRACT | Example compact ion beam sources are provided that can be used to generate ion beams using chemical species and field emitter elements or field emitter arrays. In some example, the compact ion beam source can be implemented as neutron sources based on ion beam bombardment of neutron-rich targets. |
| FILED | Wednesday, December 23, 2015 |
| APPL NO | 15/539371 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 27/26 (20130101) H01J 27/205 (20130101) Original (OR) Class H01J 37/08 (20130101) H01J 2237/082 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431455 | Abere et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Michael J. Abere (Albuquerque, New Mexico); Steven Yalisove (Ann Arbor, Michigan); Ben Torralva (Ann Arbor, Michigan) |
| ABSTRACT | The interaction between multiple intense ultrashort laser pulses and solids typically produces a regular nanoscale surface corrugation. A coupled mechanism has been identified that operates in a specific range of fluences in GaAs that exhibits transient loss of the imaginary part of the dielectric function and X2, which produces a unique corrugation known as high spatial frequency laser induced periodic surface structures (HSFL). This mechanism is unique in that the corrugation does not involve melting or ablation. |
| FILED | Friday, September 16, 2016 |
| APPL NO | 15/760549 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/53 (20151001) B23K 26/0624 (20151001) B23K 2103/56 (20180801) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02521 (20130101) H01L 21/02546 (20130101) H01L 21/02549 (20130101) H01L 21/02587 (20130101) H01L 21/02686 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431624 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Seunghoon Han (Seoul, South Korea); Yongsung Kim (Suwon-si, South Korea); Seyedeh Mahsa Kamali (Pasadena, California); Amir Arbabi (Pasadena, California); Yu Horie (Pasadena, California); Andrei Faraon (Pasadena, California); Sungwoo Hwang (Seoul, South Korea) |
| ABSTRACT | A method of manufacturing an image sensor includes: preparing a sensor substrate including: a sensor layer including a photosensitive cell; and a signal line layer including lines to receive electric signals from the photosensitive cell; forming a first material layer having a first refractive index on the sensor substrate; and forming a nanopattern layer on the first material layer, the nanopattern layer including a material having a second refractive index different from the first refractive index. |
| FILED | Monday, June 27, 2016 |
| APPL NO | 15/193229 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/76254 (20130101) H01L 21/76256 (20130101) H01L 27/1203 (20130101) H01L 27/14621 (20130101) H01L 27/14685 (20130101) Original (OR) Class H01L 27/14698 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431675 | Islam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Ahmad Ehteshamul Islam (Beavercreek, Ohio); Benji Maruyama (Yellow Springs, Ohio) |
| ABSTRACT | A carbon nanotube triode apparatus includes a plurality of Horizontally Aligned Single Wall Carbon Nano Tubes (HA-SWCNT) disposed on an electrically insulating thermally conductive substrate. A first contact is disposed on the substrate and electrically coupled to a first end of the HA-SWCNT. A second contact is disposed on the substrate and separated from a second end of the HA-SWCNT by a gap. A gate terminal is coincident with a plane of the substrate. |
| FILED | Tuesday, January 20, 2015 |
| APPL NO | 14/600380 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02118 (20130101) H01L 21/02282 (20130101) H01L 21/76251 (20130101) H01L 29/0669 (20130101) H01L 29/775 (20130101) Original (OR) Class H01L 29/66045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431733 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Weigang Wang (Tucson, Arizona); Hamid Almasi (Tucson, Arizona) |
| ABSTRACT | A perpendicular magnetic tunnel junction device (pMTJ) is provided that has a structure of a first heavy metal layer, a first thin dusting layer on the first heavy metal layer, a first CoFeB layer on the thin dusting layer, a MgO barrier layer on the first CoFeB layer, a second CoFeB layer on the MgO barrier layer, a second thin dusting layer on the CoFeB layer; and a second heavy metal layer on the thin dusting layer. The insertion of the thin dusting layer improves thermal stability of the pMTJ structure. |
| FILED | Monday, June 26, 2017 |
| APPL NO | 15/633653 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/30 (20130101) H01F 10/3254 (20130101) H01F 10/3272 (20130101) H01F 10/3286 (20130101) H01F 41/307 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) Original (OR) Class H01L 43/08 (20130101) H01L 43/10 (20130101) H01L 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431757 | Bao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Zhenan Bao (Stanford, California); Chao Wang (Sunnyvale, California); Wen Ya Lee (Palo Alto, California); Guillaume Schweicher (Ixelles, Belgium); Desheng Kong (Palo Alto, California) |
| ABSTRACT | An electronic or optoelectronic device includes: (1) a semiconductor layer; (2) a dielectric layer in contact with the semiconductor layer and including a polar elastomer; and (3) an electrode. The dielectric layer is disposed between the electrode and the semiconductor layer, and the polar elastomer includes a backbone structure and polar groups that are bonded as side chains to the backbone structure, and each of the polar groups includes 2 or more atoms. |
| FILED | Monday, April 23, 2018 |
| APPL NO | 15/960157 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/0036 (20130101) H01L 51/0043 (20130101) H01L 51/052 (20130101) H01L 51/0516 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431867 | Strong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joshua A. Strong (Ellicott City, Maryland); Max E. Nielsen (Odenton, Maryland); Peter John Andrews (Glen Burnie, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Joshua A. Strong (Ellicott City, Maryland); Max E. Nielsen (Odenton, Maryland); Peter John Andrews (Glen Burnie, Maryland) |
| ABSTRACT | One embodiment includes a clock distribution system. The system includes a first resonator spine that propagates a first clock signal and a second resonator spine that propagates a second clock signal that is out-of-phase relative to the first clock signal. The system also includes at least one resonator rib each conductively coupled to at least one of the first and second resonator spines and being arranged as a standing wave resonator with respect to a respective at least one of the first and second clock signals to inductively provide the respective at least one of the first and second clock signals to an associated circuit via a respective transformer-coupling line. The system further includes an isolation element configured to mitigate at least one of inductive and capacitive coupling between the first and second clock signals. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/012517 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/10 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) H01L 2223/6616 (20130101) H01L 2223/6627 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/082 (20130101) Original (OR) Class Pulse Technique H03K 5/15013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431892 | Garcia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alberto V. Garcia (Hartsdale, New York); Xiaoxiong Gu (White Plains, New York); Duixian Liu (Scarsdale, New York) |
| ABSTRACT | Package structures are provided having antenna-in-packages that are integrated with semiconductor RFIC (radio frequency integrated circuit) chips to form compact integrated radio/wireless communications systems that operate in the millimeter wave (mmWave) frequency range with radiation in broadside and end-fire directions. |
| FILED | Wednesday, July 12, 2017 |
| APPL NO | 15/647996 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/077 (20130101) G06K 19/07749 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 24/13 (20130101) H01L 24/16 (20130101) H01L 24/17 (20130101) H01L 24/32 (20130101) H01L 24/33 (20130101) H01L 2223/6677 (20130101) H01L 2224/131 (20130101) H01L 2224/131 (20130101) H01L 2224/16225 (20130101) H01L 2224/16225 (20130101) H01L 2224/16225 (20130101) H01L 2224/16227 (20130101) H01L 2224/17517 (20130101) H01L 2224/32013 (20130101) H01L 2224/32014 (20130101) H01L 2224/32225 (20130101) H01L 2224/32225 (20130101) H01L 2224/33181 (20130101) H01L 2224/73204 (20130101) H01L 2224/73204 (20130101) H01L 2224/73253 (20130101) H01L 2924/00 (20130101) H01L 2924/00012 (20130101) H01L 2924/014 (20130101) H01L 2924/3025 (20130101) H01L 2924/15192 (20130101) H01L 2924/15321 (20130101) H01L 2924/15322 (20130101) Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 9/0407 (20130101) Original (OR) Class H01Q 19/30 (20130101) H01Q 21/28 (20130101) H01Q 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431897 | Xin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Hao Xin (Tucson, Arizona); Qi Tang (Tucson, Arizona); Adnan Kantemur (Tucson, Arizona) |
| ABSTRACT | The present invention features a microwave gain medium having a negative refractive index, which overcompensates for loss exhibited in conventional passive metamaterials. The design consists of sub-wavelength building blocks with embedded microwave tunnel diodes exhibiting a negative refractive index and a stable net gain. The negative resistance may also be used for dispersion compensation that may enable broadband response of metamaterials. |
| FILED | Friday, December 16, 2016 |
| APPL NO | 15/382144 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/26 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 5/028 (20130101) Antennas, i.e Radio Aerials H01Q 15/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10432320 | Gorshkov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Alexey V. Gorshkov (Rockville, Maryland); Michael Foss-Feig (Baltimore, Maryland); Zachary Eldredge (Adelphi, Maryland); Zhe-Xuan Gong (College Park, Maryland); Ali Hamed Moosavian (College Park, Maryland); Jeremy T. Young (College Park, Maryland) |
| ABSTRACT | A process for generating an entangled state of a plurality of particles includes: providing the plurality of particles, the plurality of particles interacting via long range interactions; producing a first entangled state in a first particle; entangling the first particle with a second particle to form a second entangled state, wherein particles that are not in the second entangled state are remaining particles; and proceeding, starting with the second entangled state, to propagate entanglement in a logarithmic progression through the remaining particles in a recursive manner, to produce an intermediate entangled state, such that the intermediate entangled state acts as an initial entangled state for a next iteration, until a final entangled state is formed to generate the entangled state of the particles. |
| FILED | Thursday, November 02, 2017 |
| APPL NO | 15/802146 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 10/70 (20130101) H04B 10/90 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10432546 | Le et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Thai Franck Le (White Plains, New York); Erich M Nahum (New York, New York) |
| ABSTRACT | A queue management method, system, and recording medium include a queue examining device configured to examine a reverse flow queue from a forwarder for an acknowledged packet and a dropping device configured to drop a packet in a forward flow queue if the packet in the forward flow queue includes the acknowledged packet in the reverse flow queue. |
| FILED | Tuesday, August 29, 2017 |
| APPL NO | 15/689103 |
| ART UNIT | 2414 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/32 (20130101) H04L 47/40 (20130101) H04L 47/627 (20130101) Original (OR) Class H04L 47/6255 (20130101) H04L 47/6275 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10432730 | Prentice |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | David C Prentice (Springboro, Ohio) |
| ABSTRACT | An apparatus for inhibiting data on a bi-directional bus includes a first portion having a first analog port and a digital output. A second portion has a second analog port and a digital input, and the digital output is operably coupled to the first digital input. The digital output of the first portion is configured to produce a digital representation of an analog input signal presented to the first analog port. Likewise, the second analog port of the second portion is configured to produce an analog output representation of a digital signal presented to the digital input. The first and second portion cooperate to inhibit the propagation of data presented to the second analog port as an input. |
| FILED | Wednesday, January 25, 2017 |
| APPL NO | 15/415076 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 9/16 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1441 (20130101) H04L 67/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10433429 | Kelly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | James H. Kelly (West Newbury, Massachusetts); Dmitry Tolpin (Sharon, Massachusetts); Roger M. Maurais (Goffstown, New Hampshire) |
| ABSTRACT | A method is presented that improves reliability for the mechanical electrical connection formed between a grid array device, such as a pin grid array device (PGA) or a column grid array device (CGA), and a substrate such as a printed circuit board (PCB). Between adjacent PCB pads, the method increases a spacing pattern toward the periphery of the CGA, creating a misalignment between pads and columns. As part of the method, columns align with the pads, resulting in column tilt that increases from the center to the periphery of the CGA. An advantage of the method is that the column tilt reduces the amount of contractions and expansions of columns during thermal cycling, thereby increasing the projected life of CGA. Another advantage of the method is that it reduces shear stress, further increasing the projected life of the CGA. |
| FILED | Tuesday, September 20, 2016 |
| APPL NO | 15/270940 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2224/16225 (20130101) H01L 2924/00 (20130101) H01L 2924/351 (20130101) H01L 2924/381 (20130101) H01L 2924/10253 (20130101) H01L 2924/10253 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/18 (20130101) H05K 1/111 (20130101) H05K 1/181 (20130101) H05K 3/30 (20130101) H05K 3/301 (20130101) Original (OR) Class H05K 3/303 (20130101) H05K 3/3436 (20130101) H05K 2201/068 (20130101) H05K 2201/094 (20130101) H05K 2201/09418 (20130101) H05K 2201/09427 (20130101) H05K 2201/10242 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/611 (20151101) Technical Subjects Covered by Former US Classification Y10T 29/4913 (20150115) Y10T 29/49133 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10426831 | Barouch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Dan H. Barouch (Boston, Massachusetts); Bette T. Korber (Los Alamos, New Mexico); William M. Fischer (Los Alamos, New Mexico) |
| ABSTRACT | The invention provides compositions, methods, and kits for the treatment or prevention of viral infections. The polyvalent (e.g., 2-valent) vaccines described herein incorporate computationally-optimized viral polypeptides that can increase the diversity or breadth and depth of cellular immune response in vaccinated subjects. |
| FILED | Monday, April 17, 2017 |
| APPL NO | 15/489220 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 39/235 (20130101) A61K 39/275 (20130101) A61K 2039/53 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2710/24043 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) C12N 2740/16222 (20130101) C12N 2740/16234 (20130101) C12N 2740/16271 (20130101) C12N 2740/16322 (20130101) C12N 2740/16334 (20130101) Technologies for Adaptation to Climate Change Y02A 50/467 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427137 | Kyriakidou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oakridge, Tennessee) |
| INVENTOR(S) | Eleni Kyriakidou (Amherst, New York); Todd J. Toops (Knoxville, Tennessee); Jae-Soon Choi (Knoxville, Tennessee); Michael J. Lance (Knoxville, Tennessee); James E. Parks, II (Knoxville, Tennessee) |
| ABSTRACT | A catalyst for treating fuel combustion exhaust, the catalyst comprising the following components: (i) an oxide support comprising silicon oxide, aluminum oxide, or combination of silicon and aluminum oxides; (ii) cerium oxide, zirconium oxide, or a combination of cerium and zirconium oxides in contact with said oxide support; and (iii) nanoparticles comprising elemental palladium or platinum in contact with at least component (ii), wherein said palladium or platinum is present in an amount of 0.1-4 wt. % by weight of the particles, and wherein surfaces of said nanoparticles of elemental palladium or palladium are exposed and accessible to said fuel combustion exhaust. Methods of producing and using the catalyst are also described. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 15/906606 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/944 (20130101) B01D 53/9445 (20130101) B01D 2255/30 (20130101) B01D 2255/90 (20130101) B01D 2255/407 (20130101) B01D 2255/1023 (20130101) B01D 2255/2065 (20130101) B01D 2255/2092 (20130101) B01D 2255/20715 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/08 (20130101) B01J 23/10 (20130101) B01J 23/44 (20130101) Original (OR) Class B01J 23/63 (20130101) B01J 35/002 (20130101) B01J 35/04 (20130101) B01J 35/008 (20130101) B01J 35/0013 (20130101) B01J 37/0207 (20130101) B01J 37/0244 (20130101) B01J 37/0248 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/10 (20130101) F01N 2370/02 (20130101) F01N 2370/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427138 | Siriwardane |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Ranjani V. Siriwardane (Morgantown, West Virginia) |
| ABSTRACT | The invention provides a use of metal ferrite oxygen carrier for converting carbon dioxide to carbon monoxide or synthesis gas via three processes: catalytic dry reforming of methane, chemical looping dry reforming of fuel and promoting coal gasification with CO2. The metal ferrite oxygen carrier comprises MzFexOy, where MzFexOy is a chemical composition with 0<x≤4, z>0 and 0<y≤6 and M is one of Ca, Ba, and/or combinations thereof. For example, MzFexOy may be one of CaFe2O4, BaFe2O4, MgFe2O4, SrFe2O4 and/or combinations thereof. In catalytic dry reforming, methane and carbon dioxide react in the presence of metal ferrites generating a product stream comprising at least 50 vol. % CO and H2. In another embodiment, chemical looping dry reforming process where metal ferrite is reduced with a fuel and then oxidized with carbon dioxide is used for production of CO from carbon dioxide. In another embodiment, the metal ferrite is used as a promoter to produce CO continuously from coal gasification with CO2. |
| FILED | Friday, May 19, 2017 |
| APPL NO | 15/599988 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/78 (20130101) Original (OR) Class Non-metallic Elements; Compounds Thereof; C01B 3/40 (20130101) C01B 2203/066 (20130101) C01B 2203/0238 (20130101) C01B 2203/1241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427160 | Strey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Helmut Strey (Stony Brook, New York); Robert Kimmerling (Shirley, New York); Tomasz Bakowski (Levittown, New York) |
| ABSTRACT | The compositions and methods described herein are designed to introduce functionalized microparticles into droplets that can be manipulated in microfluidic devices by fields, including electric (dielectrophoretic) or magnetic fields, and extracted by splitting a droplet to separate the portion of the droplet that contains the majority of the microparticles from the part that is largely devoid of the microparticles. Within the device, channels are variously configured at Y- or T junctions that facilitate continuous, serial isolation and dilution of analytes in solution. The devices can be limited in the sense that they can be designed to output purified analytes that are then further analyzed in separate machines or they can include additional channels through which purified analytes can be further processed and analyzed. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 15/908453 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 3/502784 (20130101) Original (OR) Class B01L 7/52 (20130101) B01L 2200/0647 (20130101) B01L 2200/0673 (20130101) B01L 2300/0864 (20130101) B01L 2400/043 (20130101) B01L 2400/0487 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 2563/159 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54313 (20130101) G01N 33/54326 (20130101) G01N 33/54366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427169 | Strmcnik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Dusan Strmcnik (Lemont, Illinois); Vojislav Stamenkovic (Naperville, Illinois); Nenad Markovic (Hinsdale, Illinois) |
| ABSTRACT | An electrochemical filter system is provided that can produce an ultra-clean electrolyte solution. The filter uses a working electrode with binding sites that adsorb impurities present in the electrolyte solution using a pseudocapacitive process. |
| FILED | Wednesday, December 07, 2016 |
| APPL NO | 15/371368 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427345 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Gang Chen (Carlisle, Massachusetts); Jianjian Wang (Cambridge, Massachusetts); Jonathan Kien-Kwok Tong (Cambridge, Massachusetts); Hadi Ghasemi (Boston, Massachusetts); Xiaopeng Huang (Cambridge, Massachusetts); James Loomis (Boston, Massachusetts); Yanfei Xu (Cambridge, Massachusetts) |
| ABSTRACT | Process for continuous fabrication of highly aligned polymer films. A polymer-solvent solution is subjected to a high shear, high temperature, Couette flow to extrude a thin film having polymer chain disentanglement. The extruded thin film is frozen and the solvent is allowed to evaporate to form a dried film. The dried film is mechanically drawn using a constant force, adaptive-thickness drawing system to align polymer molecular chains through plastic deformation. A suitable polymer is ultra-high molecular weight polyethylene. |
| FILED | Thursday, April 30, 2015 |
| APPL NO | 14/700284 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/08 (20190201) B29C 48/0018 (20190201) Original (OR) Class B29C 48/022 (20190201) B29C 48/914 (20190201) B29C 48/9135 (20190201) B29C 55/005 (20130101) B29C 55/06 (20130101) B29C 55/18 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/0683 (20130101) B29K 2995/0005 (20130101) B29K 2995/005 (20130101) B29K 2995/0077 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2007/008 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 2323/06 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/04 (20130101) C08K 3/042 (20170501) C08K 3/042 (20170501) Compositions of Macromolecular Compounds C08L 23/06 (20130101) C08L 23/06 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/04 (20130101) D01F 6/06 (20130101) Ropes or Cables in General D07B 2205/201 (20130101) D07B 2205/2014 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427958 | Hunter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Steven L. Hunter (Livermore, California); Michael Stadermann (Pleasanton, California) |
| ABSTRACT | An energy transfer system is disclosed which has a controller, a first capacitor acting as a first electrode, a second capacitor acting as a second electrode, a first inductor for storing energy received from the first capacitor, and transferring the stored energy to the second capacitor, and a first plurality of electronic switches. The first plurality of electronic switches may be controlled by the controller to control a transfer of energy from the first capacitor to the first inductor, and from the first inductor to the first capacitor. An additional energy transfer subsystem may be included which has a second inductor for receiving energy from the first capacitor while the first inductor is transferring the stored energy to the second capacitor. |
| FILED | Tuesday, November 15, 2016 |
| APPL NO | 15/352058 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4691 (20130101) Original (OR) Class C02F 2101/20 (20130101) C02F 2101/163 (20130101) C02F 2201/46125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428093 | Schwarz |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Richard I. Schwarz (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard I. Schwarz (Oakland, California) |
| ABSTRACT | Herein is described a cell density signaling protein and its tissue-specific lipid cofactor. Constructs, compositions and methods for isolation, purification and use of the protein and the tissue-specific lipid cofactor are described. |
| FILED | Monday, April 25, 2016 |
| APPL NO | 15/137448 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Separation B01D 61/16 (20130101) B01D 61/145 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/572 (20130101) Original (OR) Class Peptides C07K 14/47 (20130101) C07K 14/465 (20130101) C07K 14/4705 (20130101) C07K 16/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428100 | Sampson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Matthew D. Sampson (Oak Park, Illinois); Maria K. Chan (Burr Ridge, Illinois); Alex B. Martinson (Naperville, Illinois) |
| ABSTRACT | Lead halide perovskites have proven to be a versatile class of visible light absorbers that allow rapid access to the long minority carrier lifetimes and diffusion lengths desirable for traditional single-junction photovoltaics. Computational screening identified both Fe- and Co-substituted MAPbBr3 as promising intermediate band candidate materials, and the later films were synthesized via conventional solution-based processing techniques. First-principles density functional theory (DFT) calculations support the existence of intermediate bands upon Co incorporation and enhanced sub-gap absorption, which are confirmed by UV-visible-NIR absorption spectroscopy. The simple tenability combined with steady state and time-resolved PL studies that reveal no sign of self-quenching suggest this class of materials to be promising for intermediate band photovoltaics. |
| FILED | Friday, January 13, 2017 |
| APPL NO | 15/406419 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/24 (20130101) C07F 15/065 (20130101) Original (OR) Class Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2045 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428185 | Bailey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado); The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado); The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Travis S. Bailey (Fort Collins, Colorado); Chen Guo (Newark, Delaware); Jackson T. Lewis (Fort Collins, Colorado); Kristine Fischenich (Fort Collins, Colorado); Tammy Haut Donahue (Fort Collins, Colorado); Dilanji Wijayasekara (Fort Collins, Colorado); Matthew G. Cowan (Boulder, Colorado); Douglas L. Gin (Longmont, Colorado); Richard D. Noble (Boulder, Colorado) |
| ABSTRACT | Provided herein is a block copolymer hydrogel, comprising a glass formed from a dry blend of polystyrene-poly(ethylene oxide) diblock copolymer (SO) and polystyrene-poly(ethylene oxide)-polystyrene triblock copolymer (SOS) in a molar ratio from between 95:5 and 1:99 SO/SOS and a liquid medium at a concentration between about 32:1 and about 2:1 liquid medium/SO—SOS by weight. The block copolymer hydrogel has a fatigue resistance to at least 500,000 compression cycles. Also provided are methods for forming the hydrogel. |
| FILED | Monday, December 05, 2016 |
| APPL NO | 15/539312 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Separation B01D 69/02 (20130101) B01D 71/28 (20130101) B01D 71/52 (20130101) B01D 71/76 (20130101) B01D 71/80 (20130101) B01D 2325/20 (20130101) B01D 2325/42 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0052 (20130101) B01J 2219/00051 (20130101) B01J 2219/00162 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) Original (OR) Class C08J 2353/00 (20130101) C08J 2453/00 (20130101) Compositions of Macromolecular Compounds C08L 53/00 (20130101) C08L 2207/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1653 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428324 | Coons et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | James E. Coons (Los Alamos, New Mexico); James A. Ten Cate (Los Alamos, New Mexico); Eric Y. Raby (Los Alamos, New Mexico); Daniel M. Kalb (Los Alamos, New Mexico) |
| ABSTRACT | An acoustic resonator device includes a fluid chamber with a carrier surface and a reflector surface. The fluid chamber is filled with a volume of a fluid that includes a phase-separate material such as algae. The carrier surface is coupled to a transducer, which may be a lead zirconate titanate (PZT) transducer. The transducer, when supplied with electricity, emits an acoustic wave-based output of an output frequency (e.g., ultrasound). A sensor may be used to track one or more eigenfrequencies of the volume of fluid, the acoustic resonator device, or some combination thereof. A controller may receive tracking data from the sensor and control the voltage source, the transducer, or some combination thereof to ensure that the output frequency matches one of the tracked eigenfrequencies, thereby maximizing excitation of the fluid to improve efficiency of mixing, stimulation, and separation of materials from fluid (e.g., for algal biocrude production). |
| FILED | Friday, January 06, 2017 |
| APPL NO | 15/400890 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Separation B01D 21/283 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/36 (20130101) C02F 2101/30 (20130101) Apparatus for Enzymology or Microbiology; C12M 41/42 (20130101) C12M 41/48 (20130101) C12M 47/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 13/00 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/1876 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/13 (20130101) H03H 9/176 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428334 | Fox et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Brian Grant Fox (Madison, Wisconsin); Robert Joseph Stankey (Madison, Wisconsin); Cameron Robert Currie (Madison, Wisconsin); Emily Beebe (Madison, Wisconsin) |
| ABSTRACT | A heterologous gene cassette useful for creating Streptomyces species with enhanced capability of growing on a cellulosic polysaccharide substrate, wherein the cassette comprises at least two members of the following categories: a) a GH6 gene, b) an AA10 gene, c) a GH48 gene, d) a GH5 gene and e) either (i) a GH9 gene, (ii) a GH9 gene and a GH12 gene, or (iii) a GH12 gene is disclosed. |
| FILED | Tuesday, April 04, 2017 |
| APPL NO | 15/478871 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2434 (20130101) C12N 9/2437 (20130101) C12N 15/52 (20130101) C12N 15/76 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 302/01004 (20130101) C12Y 302/01091 (20130101) C12Y 302/01176 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428342 | Wilkerson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Board of Trustees of Michigan State University (East Lansing, Michigan); The Board of Trustees of Illinois State University (Normal, Illinois) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan); Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Board of Trustees of Illinois State University (Normal, Illinois) |
| INVENTOR(S) | Curtis Wilkerson (Swartz Creek, Michigan); John Ralph (Madison, Wisconsin); Saunia Withers (Durham, North Carolina); John Sedbrook (Bloomington, Illinois) |
| ABSTRACT | The invention relates to nucleic acids encoding a p-coumaroyl-CoA:monolignol transferase and to inhibitory nucleic acids adapted to inhibit the expression and/or translation of a p-coumaroyl-CoA:monolignol transferase RNA. Inhibition of p-coumaroyl-CoA:monolignol transferase in plants improves the incorporation of monolignol ferulates into the lignin of plants, giving rise to plant biomass that is more easily processed into useful products such as paper and biofuels. |
| FILED | Friday, December 14, 2012 |
| APPL NO | 14/365744 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1029 (20130101) C12N 15/1137 (20130101) C12N 15/8218 (20130101) C12N 15/8255 (20130101) Original (OR) Class C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428397 | Dumesic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | James A. Dumesic (Verona, Wisconsin); Jeremy S. Luterbacher (Madison, Wisconsin) |
| ABSTRACT | A process to produce an aqueous solution of carbohydrates that contains C6-sugar-containing oligomers, C6 sugar monomers, C5-sugar-containing oligomers, C5 sugar monomers, or any combination thereof is presented. The process includes the steps of reacting biomass or a biomass-derived reactant with a solvent system including a lactone and water, and an acid catalyst. The reaction yields a product mixture containing water-soluble C6-sugar-containing oligomers, C6-sugar monomers, C5-sugar-containing oligomers, C5-sugar monomers, or any combination thereof. |
| FILED | Wednesday, June 28, 2017 |
| APPL NO | 15/635354 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Heterocyclic Compounds C07D 307/46 (20130101) C07D 307/50 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 3/06 (20130101) Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides C13K 1/00 (20130101) C13K 1/02 (20130101) Original (OR) Class C13K 1/06 (20130101) C13K 13/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428432 | Masel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dioxide Materials, Inc. (Boca Raton, Florida) |
| ASSIGNEE(S) | Dioxide Materials, Inc. (Boca Raton, Florida) |
| INVENTOR(S) | Richard I. Masel (Boca Raton, Florida); Zengcai Liu (Boca Raton, Florida); Robert Kutz (Boca Raton, Florida); Syed Dawar Sajjad (Boca Raton, Florida) |
| ABSTRACT | A catalyst layer for an electrochemical device comprises a catalytically active element and an ion conducting polymer. The ion conducting polymer comprises positively charged cyclic amine groups. The ion conducting polymer comprises at least one of an imidazolium, a pyridinium, a pyrazolium, a pyrrolidinium, a pyrrolium, a pyrimidium, a piperidinium, an indolium, a triazinium, and polymers thereof. The catalytically active element comprises at least one of V, Cr, Mn, Fe, Co, Ni, Cu, Sn, Zr, Nb, Mo, Ru, Rh, Pd, Ag, Cd, Hf, Ta, W, Re, Ir, Pt, Au, Hg, Al, Si, In, Tl, Pb, Bi, Sb, Te, U, Sm, Tb, La, Ce and Nd. In an electrolyzer comprising the present catalyst layer, the feed to the electrolyzer comprises at least one of CO2 and H2O. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 15/908325 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/461 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 3/04 (20130101) C25B 9/10 (20130101) C25B 11/0405 (20130101) C25B 11/0489 (20130101) Original (OR) Class C25B 13/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3335 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8668 (20130101) H01M 4/9041 (20130101) H01M 4/9083 (20130101) H01M 8/1023 (20130101) H01M 8/1044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428686 | Marsh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Siemens Energy, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | SIEMENS ENERGY, INC. (Orlando, Florida) |
| INVENTOR(S) | Jan H. Marsh (Orlando, Florida); Stephen John Messmann (Charlotte, North Carolina) |
| ABSTRACT | A turbine airfoil including a central cavity defined by an outer wall including pressure and suction sides extending between and joined at leading and trailing edges, and a chordal axis extends generally centrally between the pressure and suction sides. Rib structures located in the central cavity define radial central channels extending across the chordal axis. Radial near wall passages are defined between the rib structures and each of the pressure and suction sides of the outer wall. The radial near wall passages are each open to an adjacent central channel along a radial extent of both the near wall passages and the adjacent central channel to define a radial flow pass associated with each central channel. The flow passes are connected in series to form a serpentine cooling path extending in the direction of the chordal axis. |
| FILED | Thursday, May 08, 2014 |
| APPL NO | 15/128492 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/08 (20130101) F01D 5/18 (20130101) F01D 5/187 (20130101) F01D 5/188 (20130101) F01D 9/041 (20130101) F01D 25/12 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/123 (20130101) F05D 2240/124 (20130101) F05D 2250/185 (20130101) F05D 2260/221 (20130101) F05D 2260/2214 (20130101) F05D 2260/22141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429105 | Kariya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Harumichi Arthur Kariya (Bellflower, California); Jeffrey P. Koplow (San Ramon, California); Wayne Lawrence Staats, Jr. (Livermore, California) |
| ABSTRACT | Embodiments disclosed herein relate to devices, systems, and methods for cooling and/or heating a medium as well as cooling and/or heating an environment containing the medium. More specifically, at least one embodiment includes a heat pump that may heat and/or cool a medium and, in some instances, may transfer heat from one location to another location. |
| FILED | Thursday, September 17, 2015 |
| APPL NO | 14/857652 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 30/02 (20130101) Original (OR) Class F25B 39/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429175 | Swallow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jessica G. Swallow (Cambridge, Massachusetts); Krystyn J. Van Vliet (Lexington, Massachusetts); Harry L. Tuller (Wellesley, Massachusetts); Sean R. Bishop (Silver Spring, Maryland); Jae Jin Kim (Naperville, Illinois); James F. Smith (Denbighshire, United Kingdom) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jessica G. Swallow (Cambridge, Massachusetts); Krystyn J. Van Vliet (Lexington, Massachusetts); Harry L. Tuller (Wellesley, Massachusetts); Sean R. Bishop (Silver Spring, Maryland); Jae Jin Kim (Naperville, Illinois); James F. Smith (Denbighshire, United Kingdom) |
| ABSTRACT | Current techniques for measuring chemical expansion in thin film structures are too slow, too imprecise, or require synchrotrons. In contrast, nanoscale electrochemomechanical spectroscopy (NECS) can be used to make nanoscale measurements at time scales of seconds with simple contact or non-contact sensors. In a NECS measurement, a sample, such as thin-film oxide structure, is subjected to a temporally modulated stimulus, such as a sinusoidally alternating voltage. The stimulus causes the sample to expand, contract, deflect, or otherwise deform. A sensor, such as a contact probe or optical sensor, produces an electrical signal in response to this deformation that is correlated with the temporal modulation of the stimulus. Because the stimulus and deformation are correlated, the temporal modulation of the stimulus can be used to filter the deformation signal produced by the sensor, producing a precise, sensitive measurement of the deformation. |
| FILED | Friday, December 01, 2017 |
| APPL NO | 15/829022 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 3/002 (20130101) G01B 5/30 (20130101) G01B 11/16 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) G01N 27/021 (20130101) G01N 29/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429256 | Raja et al. |
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| FUNDED BY |
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| APPLICANT(S) | Shilpa N. Raja (Berkeley, California); Danylo Zherebetskyy (Walnut Creek, California); Siva Wu (Berkeley, California); Peter Ercius (Oakland, California); Andrew C. K. Olson (San Francisco, California); Paul Alvisatos (Berkeley, California); Robert O. Ritchie (Berkeley, California); Sanjay Govindjee (Lafayette, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Shilpa N. Raja (Berkeley, California); Danylo Zherebetskyy (Walnut Creek, California); Siva Wu (Berkeley, California); Peter Ercius (Oakland, California); Andrew C. K. Olson (San Francisco, California); Paul Alvisatos (Berkeley, California); Robert O. Ritchie (Berkeley, California); Sanjay Govindjee (Lafayette, California) |
| ABSTRACT | Nanoscale stress-sensing can be used across fields ranging from detection of incipient cracks in structural mechanics to monitoring forces in biological tissues. We demonstrate how tetrapod quantum dots (tQDs) embedded in block-copolymers act as sensors of tensile/compressive stress. Remarkably, tQDs can detect their own composite dispersion and mechanical properties, with a switch in optomechanical response when tQDs are in direct contact. Using experimental characterizations, atomistic simulations and finite-element analyses, we show that under tensile stress, densely-packed tQDs exhibit a photoluminescence peak shifted to higher energies (“blue-shift”) due to volumetric compressive stress in their core; loosely-packed tQDs exhibit a peak shifted to lower energies (“red-shift”) from tensile stress in the core. The stress-shifts result from the tQD's unique branched morphology in which the CdS arms act as antennas that amplify the stress in the CdSe core. Our nanocomposites exhibit excellent cyclability and scalability with no degraded properties of the host polymer. Colloidal tQDs allow sensing in many materials to potentially enable auto-responsive, smart structural nanocomposites that self-predict impending fracture. |
| FILED | Friday, May 26, 2017 |
| APPL NO | 15/607158 |
| ART UNIT | 1768 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 2353/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/10 (20130101) C08K 3/30 (20130101) C08K 7/16 (20130101) C08K 9/02 (20130101) C08K 2003/3027 (20130101) C08K 2003/3036 (20130101) C08K 2201/001 (20130101) C08K 2201/003 (20130101) C08K 2201/011 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/88 (20130101) C09K 11/565 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/247 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6489 (20130101) G01N 33/442 (20130101) G01N 2033/0096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429284 | Nation et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Brendan L. Nation (Albuquerque, New Mexico); Nicolas Argibay (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to an in situ testing system, which includes a wear tester and an enclosure. The wear tester is configured to apply a normal load, by way of a tip, to a surface of the test sample. Use of an enclosure allows such wear testing to be conducted in a controlled environment. |
| FILED | Tuesday, July 25, 2017 |
| APPL NO | 15/659467 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/56 (20130101) Original (OR) Class G01N 19/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429343 | Talin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Albert Alec Talin (Dublin, California); Farid El Gabaly Marquez (Berkeley, California); Elliot James Fuller (Pleasanton, California); Sapan Agarwal (Dublin, California) |
| ABSTRACT | Various technologies pertaining to a transistor having a variable-conductance channel with a non-volatile tunable conductance are described herein. The transistor comprises source and drain electrodes separated by a conducting channel layer. The conducting channel layer is separated from an electrochemical gate (ECG) layer by an electrolyte layer that prevents migration of electrons between the channel and the ECG but allows ion migration. When a voltage is applied between the channel and the ECG, electrons flow from one to the other, which causes a migration of ions from the channel to the ECG or vice versa. As ions move into or out of the channel layer, the conductance of the channel changes. When the voltage is removed, the channel maintains its conductance state. |
| FILED | Thursday, February 09, 2017 |
| APPL NO | 15/428325 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/04 (20130101) G01N 27/4148 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/145 (20130101) H01L 45/148 (20130101) H01L 45/1206 (20130101) H01L 45/1266 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429438 | Zortman et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | William A. Zortman (Corrales, New Mexico); Ryan Helinski (Albuquerque, New Mexico); Jason Hamlet (Albuquerque, New Mexico) |
| ABSTRACT | The various technologies presented herein relate to measuring a signal generated by a die-based test circuit incorporated into an IC, and utilizing the measured signal to authenticate the IC. The signal can be based upon a sensor response generated by the test circuit fabricated into the die, wherein the sensor response is based upon a property of the die material. The signal can be compared with a reference value obtained from one or more test circuit(s) respectively located on one or more reference dies, wherein the reference dies are respectively cut from different wafers, and the location at which the reference dies were cut is known. If the measured signal matches the reference value, the die is deemed to be from the same cut location as the dies from which the reference value was obtained. If the measured signal does not match the reference value, the die is not authenticated. |
| FILED | Thursday, July 28, 2016 |
| APPL NO | 15/221814 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2851 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 22/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10430159 | Crosier |
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| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Lawrence Christopher Crosier (Kansas City, Missouri) |
| ABSTRACT | A hardware random number generator comprises a gas discharge tube, an average voltage generator, and a comparator. The gas discharge tube includes first, second, and third terminals and may generate a variable voltage on the second terminal when a supply voltage is applied to the first and third terminals. The average voltage generator receives the variable voltage from the gas discharge tube and may generate an average voltage equal to a moving average value of the variable voltage over successive periods of time. The comparator receives the variable voltage and the average voltage and may generate a random stream of data bits, such that a value of each bit varies according to the relative magnitudes of the variable voltage and the average voltage. |
| FILED | Tuesday, July 18, 2017 |
| APPL NO | 15/652496 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Systems for Regulating Electric or Magnetic Variables G05F 1/618 (20130101) Electric Digital Data Processing G06F 7/588 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10430955 | Frise et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Erwin Frise (Oakland, California); Benjamin Booth (San Lorenzo, California); Charles McParland (Berkeley, California); Keith Beattie (Oakland, California); Bill Fisher (Berkeley, California); Ann S. Hammonds (Berkeley, California); Susan E. Celniker (Lafayette, California) |
| ABSTRACT | Disclosed herein are systems methods for high content screening for microscope imaging. In some embodiments, the system comprises: a microscope; and a processor configured to implement: a slide loader module; a reference imager module; a slide imager module; a region of interest (ROI) finder module; a compare imager module; a calibrator module; and an image stitcher module. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 15/692552 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/33 (20170101) G06T 7/168 (20170101) G06T 7/337 (20170101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/10056 (20130101) G06T 2207/10148 (20130101) G06T 2207/10152 (20130101) G06T 2207/20056 (20130101) G06T 2207/20061 (20130101) G06T 2207/20221 (20130101) G06T 2207/30024 (20130101) Pictorial Communication, e.g Television H04N 5/23229 (20130101) H04N 5/23293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431280 | Brennecka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Geoffrey L. Brennecka (Lakewood, Colorado); Steven F. Glover (Albuquerque, New Mexico); Gary Pena (Albuquerque, New Mexico); Fred J. Zutavern (Albuquerque, New Mexico) |
| ABSTRACT | A ferroelectric opening switch is enabled by controlled polarization switching via nucleation in a ferroelectric material, such as BaTiO3, Pb(Zr,Ti)O3, LiNbO3, LiTaO3, or variants thereof. For example, nucleation sites can be provided by mechanical seeding, grain boundaries, or optical illumination. The invention can be used as an opening switch in large scale pulsed-power systems. However, the switch can also be used in compact pulsed-power systems (e.g., as drivers for high power microwave systems), as passive fault limiters for high voltage dc (HVDC) systems, and/or in other high power applications. |
| FILED | Monday, April 25, 2016 |
| APPL NO | 15/137539 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431419 | Kovarik et al. |
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| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Libor Kovarik (West Richland, Washington); Andrew J. Stevens (Richland, Washington); Andrey V. Liyu (Pasco, Washington); Nigel D. Browning (Richland, Washington) |
| ABSTRACT | Sparse sampling approaches and probe systems for analytical instruments are disclosed providing for effective sub-sampling of a specimen and inpainting to reconstruct representations of actual information. The sub-sampling involves serial acquisition of contiguous measured values lying at positions along a scan path extending in a line toward a first direction and having random perturbations in a second direction. The perturbations are limited within a predetermined distance from the line. Inpainting techniques are utilized among the measured values to reconstruct a representation of actual information regarding the specimen. |
| FILED | Friday, July 07, 2017 |
| APPL NO | 15/643862 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/28 (20130101) H01J 37/222 (20130101) Original (OR) Class H01J 2237/226 (20130101) H01J 2237/2802 (20130101) H01J 2237/2809 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431624 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Seunghoon Han (Seoul, South Korea); Yongsung Kim (Suwon-si, South Korea); Seyedeh Mahsa Kamali (Pasadena, California); Amir Arbabi (Pasadena, California); Yu Horie (Pasadena, California); Andrei Faraon (Pasadena, California); Sungwoo Hwang (Seoul, South Korea) |
| ABSTRACT | A method of manufacturing an image sensor includes: preparing a sensor substrate including: a sensor layer including a photosensitive cell; and a signal line layer including lines to receive electric signals from the photosensitive cell; forming a first material layer having a first refractive index on the sensor substrate; and forming a nanopattern layer on the first material layer, the nanopattern layer including a material having a second refractive index different from the first refractive index. |
| FILED | Monday, June 27, 2016 |
| APPL NO | 15/193229 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/76254 (20130101) H01L 21/76256 (20130101) H01L 27/1203 (20130101) H01L 27/14621 (20130101) H01L 27/14685 (20130101) Original (OR) Class H01L 27/14698 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431706 | Ku et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Peicheng Ku (Ann Arbor, Michigan); Nanditha Dissanayake (Ann Arbor, Michigan); Brian Roberts (Ann Arbor, Michigan) |
| ABSTRACT | A photoactive device that includes a photovoltaic device having electrodes and at least one photoactive layer between the electrodes. One or more other layers may be included between the electrodes. The device includes a substrate positioned below the photovoltaic device, and a nanostructure backreflective layer positioned below the substrate such that at least some of the incident light impinging on the photovoltaic device passes through the photovoltaic device and the substrate and is backscattered through the substrate to the photovoltaic device. |
| FILED | Sunday, February 09, 2014 |
| APPL NO | 14/176097 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/056 (20141201) Original (OR) Class H01L 51/447 (20130101) H01L 51/4253 (20130101) H01L 2251/308 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/22 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431820 | Croy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Jason Croy (Plainfield, Illinois); Mahalingam Balasubramanian (Naperville, Illinois); Joong Sun Park (Woodridge, Illinois) |
| ABSTRACT | The surface of a lithium ion cathode material (e.g., a lithium metal oxide material capable of releasing and accepting lithium ions during charging and discharging, respectively, of a lithium ion electrochemical cell) is coated with a lithium metal oxide (LMO) material comprising a high-valent metal to, inter alia, reduce interfacial resistance toward lithium exchange. Li-rich phases on the surface of the treated LMO particles allow for better lithium ion diffusion. The inclusion of elements that form phases with lithium and can substitute in the host structure allow for mixing across interfaces leading to more robust structures that better mimic epitaxial-type layers. Inclusion of doping elements in place of some of the high-valent metal in the surface-treating composition provides unexpectedly improved performance over surface treatments comprising lithium metal oxides that only include a high-valent metal. |
| FILED | Monday, July 10, 2017 |
| APPL NO | 15/645678 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/366 (20130101) H01M 4/485 (20130101) Original (OR) Class H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/1391 (20130101) H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10432134 | Keenihan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DOW GLOBAL TECHNOLOGIES LLC (Midland, Michigan) |
| ASSIGNEE(S) | DOW GLOBAL TECHNOLOGIES LLC (Midland, Michigan) |
| INVENTOR(S) | James R. Keenihan (Midland, Michigan); Leonardo C. Lopez (Midland, Michigan); Kwanho Yang (Midland, Michigan); Joseph A. Langmaid (Caro, Michigan) |
| ABSTRACT | A solar module (2) comprising; (a) an active portion (4) and (b) a support portion (6), wherein the support portion (8) includes a plurality of reinforcement ribs (20) in a series of interconnected or partially interconnected patterns. The solar module (2) may include an intermediate portion (6C) acting as a structural interface between the active portion (4) and the support portion (6). The intermediate portion (6C) may include one or more gate locations (10, 12). The plurality of reinforcement ribs (20) may extend at an angle along the support portion (6) so that an effective modulus of the support portion (6) along a width direction is substantially equal to an effective modulus of the support portion (6) along a length direction. |
| FILED | Monday, April 07, 2014 |
| APPL NO | 14/786083 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0481 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/25 (20141201) Original (OR) Class Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 10/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10433412 | Mao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Hann-Shin Mao (Richmond, California); Wim Leemans (Kensington, California); Stepan Bulanov (Concord, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to laser plasma accelerators. In one aspect a block of material defines a gas inlet, a chamber in fluid communication with the gas inlet, a throat in fluid communication with the chamber, a channel in fluid communication with the throat, and a gas outlet in fluid communication with the channel. The throat is configured to generate a supersonic flow of a gas when the gas flows through the throat. The channel includes a ramp that is positioned proximate the gas outlet, with the ramp being inclined at an angle with respect to a direction of a flow of the gas proximate a surface of the channel prior to the ramp at the gas outlet. |
| FILED | Monday, February 12, 2018 |
| APPL NO | 15/894422 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1001 (20130101) A61N 5/1007 (20130101) A61N 2005/1022 (20130101) A61N 2005/1088 (20130101) A61N 2005/1089 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 5/02 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/11 (20130101) H01S 3/0057 (20130101) H01S 3/1625 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/54 (20130101) Original (OR) Class H05H 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10433458 | Cader et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
| INVENTOR(S) | Tahir Cader (Liberty Lake, Washington); Harvey Lunsman (Chippewa Falls, Wisconsin) |
| ABSTRACT | Cold plates are described herein. In one example, a cold plate can include a thermally conductive plastic forming a coolant channel that includes a heat spreader formed into the thermally conductive plastic and an exterior surface of the thermally conductive plastic with a coupling location to couple a heat pipe to the exterior surface of the thermally conductive plastic. |
| FILED | Tuesday, May 08, 2018 |
| APPL NO | 15/973705 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/0233 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/04 (20130101) F28F 21/065 (20130101) Electric Digital Data Processing G06F 1/20 (20130101) G06F 2200/201 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/427 (20130101) H01L 23/473 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20254 (20130101) Original (OR) Class H05K 7/20336 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10426348 | Nolte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | David D. Nolte (Lafayette, Indiana); John J. Turek (West Lafayette, Indiana) |
| ABSTRACT | A phenotypic profiling method for drug/dose physiological response of living bodies utilizes feature recognition to segment the information in time-frequency tissue-response spectrograms to construct N-dimensional feature vectors. The feature vectors are used to generate a correlation matrix among a large number of different stimuli in the form of drugs, doses and conditions. Multi-dimensional scaling is applied to the correlation matrix to form a two-dimensional map of response relationships that retains rank distances from the higher-dimensionality feature matrix. The two-dimensional phenotypic profile space displays compact regions indicative of particular physiological responses, such as regions of enhanced active transport, membrane undulations and blebbing. |
| FILED | Wednesday, February 06, 2013 |
| APPL NO | 13/760827 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) Original (OR) Class Holographic Processes or Apparatus G03H 1/08 (20130101) G03H 1/0443 (20130101) G03H 2210/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426850 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Michael S. Yu (Timonium, Maryland); Yang Li (Baltimore, Maryland); Daniel Summerfield (Baltimore, Maryland); Allen Yi-Lan Wang (Belle Mead, New Jersey); Catherine A. Foss (Baltimore, Maryland); Martin G. Pomper (Baltimore, Maryland) |
| ABSTRACT | The present invention provides both a caged collagen mimetic peptide (CCMP) having the formula: L-S-Zm-[Gly-X-Y]n-LGly-X-Y-[Gly-X-Y]n (SEQ ID NO: 19); wherein L is one or more detectable moieties; S is one or more spacer molecules; Zm is any amino acid where m is an integer of 1 to 10; X is proline or modified proline; Y is proline or modified proline; Gly is glycine; n is an integer from 1 to 20; and LGly is a glycine covalently linked to a cage moiety comprising a labile protecting group, as well as a collagen mimetic peptides lacking the labile protecting group (CMP). The inventions are useful for binding collagen and denatured collagen and/or gelatin both in vitro and in vivo, and are useful for targeting any organ or tissue where collagen is present, and can be used for research and diagnostic imaging (both in vivo and in vitro) and also for in vivo therapeutic applications. |
| FILED | Friday, November 16, 2012 |
| APPL NO | 13/679431 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/39 (20130101) A61K 49/0056 (20130101) Original (OR) Class Peptides C07K 14/78 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6887 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/55 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427160 | Strey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Helmut Strey (Stony Brook, New York); Robert Kimmerling (Shirley, New York); Tomasz Bakowski (Levittown, New York) |
| ABSTRACT | The compositions and methods described herein are designed to introduce functionalized microparticles into droplets that can be manipulated in microfluidic devices by fields, including electric (dielectrophoretic) or magnetic fields, and extracted by splitting a droplet to separate the portion of the droplet that contains the majority of the microparticles from the part that is largely devoid of the microparticles. Within the device, channels are variously configured at Y- or T junctions that facilitate continuous, serial isolation and dilution of analytes in solution. The devices can be limited in the sense that they can be designed to output purified analytes that are then further analyzed in separate machines or they can include additional channels through which purified analytes can be further processed and analyzed. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 15/908453 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 3/502784 (20130101) Original (OR) Class B01L 7/52 (20130101) B01L 2200/0647 (20130101) B01L 2200/0673 (20130101) B01L 2300/0864 (20130101) B01L 2400/043 (20130101) B01L 2400/0487 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 2563/159 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54313 (20130101) G01N 33/54326 (20130101) G01N 33/54366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427188 | Oralkan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Omer Oralkan (Morrisvilee, North Carolina); Feysel Yalcin Yamaner (Istanbul, Turkey); Xiao Zhang (Raleigh, North Carolina) |
| ABSTRACT | A capacitive micromachined ultrasonic transducer (CMUT) and methods of forming the same are disclosed herein. In one implementation, the CMUT comprises a glass substrate having a cavity; a patterned metal bottom electrode situated within the cavity of the glass substrate; and a vibrating plate comprising at least a conducting layer, wherein the vibrating plate is anodically bonded to the glass substrate to form an air-tight seal between the vibrating plate and the substrate and wherein a pressure inside the cavity is less than atmospheric pressure (i.e., a vacuum). In another implementation, the CMUT comprises a glass substrate with Through-Glass-Via (TGV) interconnects, wherein a metal electrode is electrically connected to a TGV and wherein said metal electrode can be in the bottom of a cavity of the glass substrate or on the vibrating plate. |
| FILED | Monday, August 01, 2016 |
| APPL NO | 15/225118 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0215 (20130101) B06B 1/0292 (20130101) Original (OR) Class B06B 2201/51 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/047 (20130101) B81B 2201/0271 (20130101) B81B 2201/0292 (20130101) B81B 2207/053 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 3/001 (20130101) B81C 2203/031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427194 | Westerhoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul K. Westerhoff (Scottsdale, Arizona); Paul Dahlen (Tempe, Arizona); Onur Apul (Phoenix, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Paul K. Westerhoff (Scottsdale, Arizona); Paul Dahlen (Tempe, Arizona); Onur Apul (Phoenix, Arizona) |
| ABSTRACT | A soil remediation method for treating contaminated soil includes combining a dielectric carbonaceous nanomaterial with the contaminated soil to yield a composite contaminated soil, and irradiating the composite contaminated soil with microwave radiation to yield a remediated soil. The composite contaminated soil includes at least 1 wt % of the dielectric carbonaceous material, and the microwave radiation provides an energy input of at least 2.5 kWh per kilogram of the composite contaminated soil. |
| FILED | Thursday, September 28, 2017 |
| APPL NO | 15/719011 |
| ART UNIT | 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Reclamation of Contaminated Soil B09C 1/00 (20130101) B09C 1/06 (20130101) Original (OR) Class B09C 1/08 (20130101) B09C 2101/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427293 | Asbeck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Prisident and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Alan Thomas Asbeck (Waltham, Massachusetts); Ignacio Galiana Bujanda (Cambridge, Massachusetts); Ye Ding (Cambridge, Massachusetts); Robert Joseph Dyer (Concord, Massachusetts); Arnar Freyr Larusson (Hanover, New Hampshire); Brendan Thomas Quinlivan (Rutland, Massachusetts); Kai Schmidt (Berlin, Germany); Diana Wagner (Charlotte, North Carolina); Conor J. Walsh (Cambridge, Massachusetts); Michael Wehner (Berkeley, California) |
| ABSTRACT | In at least one aspect, there is provided a system for generating force about one or more joints including a soft exosuit having a plurality of anchor elements and at least one connection element disposed between the plurality of anchor elements. The system also includes at least one sensor to determine a force the at least one connection element or at least one of the plurality of anchor elements and to output signals relating to the force, at least one actuator configured to change a tension in the soft exosuit and at least one controller configured to receive the signals output from the at least one sensor and actuate the at least one actuator responsive to the received signals. |
| FILED | Tuesday, March 17, 2015 |
| APPL NO | 14/660704 |
| ART UNIT | 3652 — Material and Article Handling |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/024 (20130101) A61H 1/0244 (20130101) A61H 1/0266 (20130101) A61H 3/00 (20130101) A61H 2201/149 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/501 (20130101) A61H 2201/1215 (20130101) A61H 2201/1238 (20130101) A61H 2201/1246 (20130101) A61H 2201/1261 (20130101) A61H 2201/1481 (20130101) A61H 2201/1628 (20130101) A61H 2201/1652 (20130101) A61H 2201/1664 (20130101) A61H 2201/1671 (20130101) A61H 2201/5002 (20130101) A61H 2201/5007 (20130101) A61H 2201/5061 (20130101) A61H 2201/5064 (20130101) A61H 2201/5069 (20130101) A61H 2201/5079 (20130101) A61H 2201/5084 (20130101) A61H 2201/5097 (20130101) A61H 2230/60 (20130101) A61H 2230/605 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427938 | Panchapakesan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| INVENTOR(S) | Balaji Panchapakesan (Louisville, Kentucky) |
| ABSTRACT | A device and method detect cellular targets in a bodily source by utilizing a biofunctional pad comprised of a thin film of carbon nanotubes (CNT's). When antibodies are absorbed by the CNT's, cellular targets having markers matching the antibodies may be detected in a bodily source placed upon the biofunctional pad by measuring the conductivity of the thin film using conductive contacts electrically coupled to the thin film, as the binding of the receptors in the cellular targets to the antibodies changes the free energy in the thin film. In many respects, the device functions as a Field Effect Transistor (FET) with the bodily source, e.g., blood, acting as a polyelectrolyte liquid gate electrode to create a varying electrostatic charge or capacitance in the thin film based upon the binding of cellular targets in the source to the antibodies present on the biofunctional pad. |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/897851 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Original (OR) Class B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 27/4146 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/1039 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427946 | Orlovskaya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Nina Orlovskaya (Orlando, Florida); Richard Blair (Oviendo, Florida); Zhilin Xie (Oviendo, Florida); David A. Cullen (Oak Ridge, Tennessee) |
| ABSTRACT | The present disclosure relates generally to a composition comprising at least one of iridium diboride and iridium monoboride, and methods of making such. The present disclosure also relates to a composition comprising iridium monoboride and at least one of (a) rows of single iridium atoms and/or (b) one or more clusters of iridium atoms, and methods of making such. |
| FILED | Tuesday, October 27, 2015 |
| APPL NO | 15/522702 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/04 (20130101) Original (OR) Class Alloys C22C 1/1084 (20130101) C22C 29/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428043 | Caradonna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | John Philip Caradonna (Boston, Massachusetts); Paul Christopher Tarves (Boston, Massachusetts); Joshua McNally (Boston, Massachusetts); Lauren Gregor Tighe (Boston, Massachusetts) |
| ABSTRACT | Disclosed herein are reaction compositions comprising an oxidation catalyst, a solvent, and a substrate that is dissolved in the solvent. The oxidation catalyst comprises a metal ion complexed with an α-keto acid and a tridentate N,N,O-ligand. Also disclosed herein are methods for oxidizing a C—H bond of a molecule, the methods comprising contacting the molecule with a metal complex comprising a metal ion complexed with a tridentate N,N,O-ligand in the presence of an α-keto acid and a solvent. In some embodiments, the oxidation catalyst or metal complex is linked to a solid support. |
| FILED | Friday, December 18, 2015 |
| APPL NO | 15/537746 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/18 (20130101) B01J 31/1815 (20130101) B01J 31/2226 (20130101) B01J 2231/70 (20130101) B01J 2531/0252 (20130101) B01J 2531/842 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 41/00 (20130101) Acyclic or Carbocyclic Compounds C07C 27/12 (20130101) C07C 29/50 (20130101) C07C 29/50 (20130101) C07C 29/50 (20130101) C07C 31/02 (20130101) C07C 35/18 (20130101) C07C 35/20 (20130101) C07C 37/58 (20130101) C07C 45/27 (20130101) C07C 45/33 (20130101) C07C 45/33 (20130101) C07C 45/34 (20130101) C07C 45/34 (20130101) C07C 45/36 (20130101) C07C 45/36 (20130101) C07C 45/38 (20130101) C07C 45/38 (20130101) C07C 46/04 (20130101) C07C 46/04 (20130101) C07C 47/02 (20130101) C07C 47/04 (20130101) C07C 49/04 (20130101) C07C 49/413 (20130101) C07C 49/603 (20130101) C07C 49/675 (20130101) C07C 50/18 (20130101) C07C 51/235 (20130101) C07C 2601/16 (20170501) C07C 2601/18 (20170501) C07C 2603/24 (20170501) Heterocyclic Compounds C07D 211/22 (20130101) C07D 301/06 (20130101) C07D 401/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428101 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Xi Chen (Davis, California); Hai Yu (Woodland, California); Joel Hwang (Davis, California) |
| ABSTRACT | The present invention provides a method of preparing an isolated oligosaccharide or glycolipid by preparing the oligosaccharide or glycolipid having a hydrophobic group, such as a perfluorinated alkyl or a fatty acid, and separating the oligosaccharide or glycolipid using a solid-phase extraction cartridge. |
| FILED | Monday, June 16, 2014 |
| APPL NO | 14/897596 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/11 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 15/04 (20130101) Original (OR) Class C07H 15/08 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101) C12P 19/18 (20130101) C12P 19/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428160 | Rege et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); BANNER HEALTH an Arizona nonprofit corporation (Phoenix, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); BANNER HEALTH An Arizona Nonprofit Corporation (Phoenix, Arizona) |
| INVENTOR(S) | Kaushal Rege (Chandler, Arizona); Karthik Subramaniam Pushpavanam (Tempe, Arizona); Stephen Sapareto (Apache Junction, Arizona) |
| ABSTRACT | An apparatus includes a hydrogel including a metallic compound, a surfactant, an acid, agarose and water. The hydrogel is substantially colorless. A radiated hydrogel having a color is formed when the hydrogel receives a low dose of ionizing radiation. |
| FILED | Monday, July 10, 2017 |
| APPL NO | 15/645914 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 7/00 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0039 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2305/12 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/08 (20130101) C08K 3/30 (20130101) C08K 2003/0831 (20130101) C08K 2003/3009 (20130101) Compositions of Macromolecular Compounds C08L 5/12 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428171 | Cheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Jianjun Cheng (Champaign, Illinois); Hanze Ying (Champaign, Illinois) |
| ABSTRACT | The present invention relates to a one-component processing method and system for preparing polyurea materials. This method and system involves a polymerization process using cyclic oligomeric polyurea precursors. These cyclic oligomeric precursors have dynamic urea bonds such as hindered urea bonds (HUBs). These cyclic oligomeric precursors exhibit dynamic properties to reversibly dissociate in situ yielding isocyanate and amine components which polymerize to yield the polyureas, such as linear, branched or cross-linked polyureas. This method and system has advantages over conventional methods that utilize two-component systems. Such two-component systems require the segregation of the isocyanate and amine components to prevent premature or too rapid polymerization. The resulting polyureas are useful for a variety of applications including coatings. |
| FILED | Wednesday, February 03, 2016 |
| APPL NO | 15/547525 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/325 (20130101) C08G 18/757 (20130101) C08G 18/792 (20130101) C08G 18/3228 (20130101) Original (OR) Class C08G 71/02 (20130101) C08G 2150/20 (20130101) Compositions of Macromolecular Compounds C08L 75/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/03 (20130101) C09D 175/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428185 | Bailey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado); The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado); The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Travis S. Bailey (Fort Collins, Colorado); Chen Guo (Newark, Delaware); Jackson T. Lewis (Fort Collins, Colorado); Kristine Fischenich (Fort Collins, Colorado); Tammy Haut Donahue (Fort Collins, Colorado); Dilanji Wijayasekara (Fort Collins, Colorado); Matthew G. Cowan (Boulder, Colorado); Douglas L. Gin (Longmont, Colorado); Richard D. Noble (Boulder, Colorado) |
| ABSTRACT | Provided herein is a block copolymer hydrogel, comprising a glass formed from a dry blend of polystyrene-poly(ethylene oxide) diblock copolymer (SO) and polystyrene-poly(ethylene oxide)-polystyrene triblock copolymer (SOS) in a molar ratio from between 95:5 and 1:99 SO/SOS and a liquid medium at a concentration between about 32:1 and about 2:1 liquid medium/SO—SOS by weight. The block copolymer hydrogel has a fatigue resistance to at least 500,000 compression cycles. Also provided are methods for forming the hydrogel. |
| FILED | Monday, December 05, 2016 |
| APPL NO | 15/539312 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Separation B01D 69/02 (20130101) B01D 71/28 (20130101) B01D 71/52 (20130101) B01D 71/76 (20130101) B01D 71/80 (20130101) B01D 2325/20 (20130101) B01D 2325/42 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0052 (20130101) B01J 2219/00051 (20130101) B01J 2219/00162 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) Original (OR) Class C08J 2353/00 (20130101) C08J 2453/00 (20130101) Compositions of Macromolecular Compounds C08L 53/00 (20130101) C08L 2207/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1653 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428380 | Ju et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Zengmin Li (Flushing, New York); John Robert Edwards (St. Louis, Missouri); Yasuhiro Itagaki (New York, New York) |
| ABSTRACT | This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analog after the nucleotide analog is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotide analogs which comprise unique labels attached to the nucleotide analog through a cleavable linker, and a cleavable chemical group to cap the —OH group at the 3′-position of the deoxyribose. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/150191 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/11 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) C07H 19/14 (20130101) C07H 21/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6872 (20130101) C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/117 (20130101) C12Q 2525/186 (20130101) C12Q 2525/186 (20130101) C12Q 2535/101 (20130101) C12Q 2535/101 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2563/107 (20130101) C12Q 2563/107 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428444 | Meng et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachussetts (Boston, Massachusetts) |
| INVENTOR(S) | Xiangxi Meng (Sunderland, Massachusetts); Sarah L. Perry (Belchertown, Massachusetts); Jessica D. Schiffman (Amherst, Massachusetts) |
| ABSTRACT | The invention provides novel polymer nanofiber or microfiber mats or membranes and methods for their preparation via an aqueous, one-step polyelectrolyte complexation and electrospinning of complex coacervates. |
| FILED | Thursday, October 05, 2017 |
| APPL NO | 15/725465 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2400/12 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 12/30 (20130101) C08F 26/04 (20130101) C08F 28/02 (20130101) Compositions of Macromolecular Compounds C08L 25/18 (20130101) C08L 39/00 (20130101) C08L 39/04 (20130101) C08L 41/00 (20130101) C08L 2205/16 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0038 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/26 (20130101) Original (OR) Class D01F 6/44 (20130101) D01F 6/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429170 | Hendon et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Christine Hendon (Riverdale, New York); Xinwen Yao (New York, New York); Yuye Ling (New York, New York) |
| ABSTRACT | An exemplary system can be provided which can include, for example, a plurality of source arrangements configured to provide a plurality of electro-magnetic radiations to at least one of at least one sample or at least one reference structure, a first arrangement configured to receive a first radiation(s) from the reference structure(s), a second arrangement configured to receive a second radiation(s) from the sample(s), where a portion(s) of the second radiation(s) can be in an invisible spectrum, a third arrangement configured to combine the first radiation(s) and the second radiation(s) into a third radiation(s), and a fourth arrangement configured to convert the third radiation(s) into a further radiation in a visible spectrum based on the at least one portion. |
| FILED | Wednesday, November 25, 2015 |
| APPL NO | 15/531230 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02004 (20130101) Original (OR) Class G01B 9/02041 (20130101) G01B 9/02091 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3544 (20130101) G02F 1/3558 (20130101) G02F 1/3775 (20130101) G02F 2001/3548 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429328 | Lin et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Qiao Lin (New York, New York); Bin Wang (New York, New York) |
| ABSTRACT | A microelectromechanical systems-based calorimetric device includes first and second micromixers and first and second thermally-isolated microchambers. A first solution including a sample and a reagent is introduced to the first microchamber via the first micromixer, and a second solution including a sample and a buffer is introduced to the second microchamber via the second micromixer. A thermopile measures the differential temperature between the first microchamber and the second microchamber and outputs a voltage representative of the difference. The output voltage can be used to calculate reaction parameters. |
| FILED | Friday, January 23, 2015 |
| APPL NO | 14/603848 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 7/00 (20130101) B01L 2200/14 (20130101) B01L 2200/027 (20130101) B01L 2300/0663 (20130101) B01L 2300/0877 (20130101) B01L 2300/0883 (20130101) B01L 2300/1827 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/482 (20130101) Original (OR) Class G01N 25/4893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429361 | Sims et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Carl W. Sims (Santa Rosa, California); Peter W. Carr (St. Paul, Minnesota); Marcelo Roberto Filgueira (Downingtown, Pennsylvania); Klaus Witt (Keltern, Germany) |
| ABSTRACT | A multi-dimensional liquid analysis system includes a flow splitter for separating mobile phase outflow from a first dimension liquid analysis system into first and second liquid split outlet flows. Volumetric flow rate control of the split outlet flows is provided by a flow control pump which withdraws one of the split outlet flows from the flow splitter at a controlled withdrawal flow rate to define the other split outlet flow rate as the difference between the outflow rate from the first dimension system and the withdrawal flow rate. In this manner, accurate and consistent flow division can be accomplished, which is particularly useful for multi-dimensional liquid analysis. |
| FILED | Friday, January 15, 2016 |
| APPL NO | 14/996784 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/10 (20130101) G01N 30/32 (20130101) G01N 30/463 (20130101) Original (OR) Class G01N 30/465 (20130101) G01N 30/7233 (20130101) G01N 2030/324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429368 | Murphy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Roger Williams University (Bristol, Rhode Island) |
| ASSIGNEE(S) | Roger Williams University (Bristol, Rhode Island) |
| INVENTOR(S) | Clifford Brewster Murphy (North Attleboro, Massachusetts); Clifford John Timpson (Little Compton, Rhode Island) |
| ABSTRACT | The present invention provides a novel and unique device, method and system that detects thiocyanate in seawater with the halide ions present that can be provided in a hand-portable device that offers detection limits to 1-2 ppb which at least twice as sensitive as the nearest known device in the current state of the art. The sensor is also sensitive to nitrate ions (NO3−) in seawater at similar ppb concentrations as thiocyanate. |
| FILED | Thursday, October 19, 2017 |
| APPL NO | 15/787867 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/48 (20130101) G01N 33/182 (20130101) G01N 33/1826 (20130101) Original (OR) Class G01N 33/1886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429376 | Soper et al. |
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| FUNDED BY |
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| APPLICANT(S) | Steven A. Soper (Baton Rouge, Louisiana); Michael C. Murphy (Baton Rouge, Louisiana); June Feng (Shreveport, Louisiana); Robin L. McCarley (Prairieville, Louisiana); André A. Adams (Burke, Virginia) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| INVENTOR(S) | Steven A. Soper (Baton Rouge, Louisiana); Michael C. Murphy (Baton Rouge, Louisiana); June Feng (Shreveport, Louisiana); Robin L. McCarley (Prairieville, Louisiana); André A. Adams (Burke, Virginia) |
| ABSTRACT | Microdevices are disclosed to efficiently, accurately, and rapidly isolate and enumerate rare cells, such as circulating tumor cells, from liquids such as whole blood. The system employs multiple parallel meandering channels having a width on the order of 1-2 cell diameters. The microdevices can be produced at low-cost, may readily be automated, and in many instances may be used without pre-processing of the sample. They may be used to isolate and enumerate rare cells, including for example the detection and diagnosis of cancers, cancer staging, or evaluating the effectiveness of a therapeutic intervention, or detecting pathogenic bacteria. The device may optionally be used to nondestructively capture and later to release target cells. |
| FILED | Wednesday, May 13, 2009 |
| APPL NO | 12/992225 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0883 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 15/1484 (20130101) G01N 33/49 (20130101) Original (OR) Class G01N 33/4915 (20130101) G01N 2015/1006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429386 | Fritz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Heather Fritz (Davis, California); Patricia Conrad (Davis, California) |
| ABSTRACT | The present disclosure provides antibodies that bind the surface of Toxoplasma gondii oocysts, methods for using such antibodies and kits and devices for practicing such methods. Such antibodies, methods, kits and devices find use in detection of T. gondii oocysts and the isolation of such oocysts from samples including environmental samples, food-based samples, diagnostic samples, and the like. |
| FILED | Tuesday, March 08, 2016 |
| APPL NO | 15/548062 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/20 (20130101) C07K 2317/33 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56905 (20130101) Original (OR) Class G01N 2333/45 (20130101) G01N 2469/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431108 | Chestnut et al. |
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| FUNDED BY |
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| APPLICANT(S) | NSF International (Ann Arbor, Michigan) |
| ASSIGNEE(S) | NSF International (Ann Arbor, Michigan) |
| INVENTOR(S) | Thomas Chestnut (Saline, Michigan); Jennifer Leighanne Tong (Troy, Ohio) |
| ABSTRACT | Computer-implemented techniques for interactively training a user in performing a predetermined task related to at least one of food safety, workplace safety and food quality using a head wearable device are provided. The head wearable device comprises a digital display positioned within a field of view of the user, a camera to capture visual data from a first-person perspective, a user input device to provide control signals, and a processor. A series of steps are visually presented on the digital display in a predetermined order to direct the user through a process of performing the task. Visual data captured by the camera and the control signals provided from the user input device are analyzed during performance of one or more steps of the task. The computer-implemented techniques evaluate the user's performance of the one or more steps based on analysis of the visual data and the control signals. |
| FILED | Tuesday, April 05, 2016 |
| APPL NO | 15/091351 |
| ART UNIT | 2627 — Selective Visual Display Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) G02B 2027/014 (20130101) G02B 2027/0141 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/14 (20130101) G06F 3/16 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00335 (20130101) G06K 9/00671 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0639 (20130101) G06Q 30/018 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/00 (20130101) G09B 5/02 (20130101) Original (OR) Class G09B 19/003 (20130101) G09B 19/0076 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 5/12 (20130101) G09G 2370/02 (20130101) G09G 2370/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431726 | Ozturk et al. |
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| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Mehmet Ozturk (Raleigh, North Carolina); Michael D. Dickey (Raleigh, North Carolina); Collin Ladd (Raleigh, North Carolina); Dishit Paresh Parekh (Raleigh, North Carolina); Viswanath Padmanabhan Ramesh (Raleigh, North Carolina); Francisco Suarez (Raleigh, North Carolina) |
| ABSTRACT | Flexible thermoelectric generators and methods of manufacturing are disclosed. In one embodiment, a flexible thermoelectric generator includes a plurality of pillars, a first and a second plurality of flexible interconnects, and a flexible material. The plurality of pillars having a first side and a second side. The first plurality of flexible interconnects electrically connecting pairs of the plurality of pillars on the first side. The second plurality of flexible interconnects electrically connecting the pairs of plurality of pillars on the second side. The first and the second plurality of flexible interconnects alternate among the pairs of plurality of pillars to form an electrical circuit having a first end and a second end. The flexible material covering the first and second plurality of flexible interconnects and having an external surface. The flexible material is configured to conduct thermal energy from the external surface to the plurality of pillars. |
| FILED | Tuesday, May 02, 2017 |
| APPL NO | 15/584350 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/02 (20130101) H01L 35/30 (20130101) H01L 35/32 (20130101) Original (OR) Class H01L 35/225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431733 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Weigang Wang (Tucson, Arizona); Hamid Almasi (Tucson, Arizona) |
| ABSTRACT | A perpendicular magnetic tunnel junction device (pMTJ) is provided that has a structure of a first heavy metal layer, a first thin dusting layer on the first heavy metal layer, a first CoFeB layer on the thin dusting layer, a MgO barrier layer on the first CoFeB layer, a second CoFeB layer on the MgO barrier layer, a second thin dusting layer on the CoFeB layer; and a second heavy metal layer on the thin dusting layer. The insertion of the thin dusting layer improves thermal stability of the pMTJ structure. |
| FILED | Monday, June 26, 2017 |
| APPL NO | 15/633653 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/30 (20130101) H01F 10/3254 (20130101) H01F 10/3272 (20130101) H01F 10/3286 (20130101) H01F 41/307 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) Original (OR) Class H01L 43/08 (20130101) H01L 43/10 (20130101) H01L 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10432002 | Shoari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arian Shoari (San Diego, California); Mona Komeijani (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arian Shoari (San Diego, California); Mona Komeijani (San Diego, California) |
| ABSTRACT | This disclosure describes methods and apparatus sustainable battery charging. In one of the embodiments, a charger and plugging mechanism is presented to prevent overcharging of the battery. The plug will automatically detach the power cord from the device when the battery is fully charged. Other feedback controlled detaching mechanisms has also been disclosed such as the one disconnects the charger cord when the internal temperature of the device gets hotter than a preset threshold. |
| FILED | Monday, September 04, 2017 |
| APPL NO | 15/694979 |
| ART UNIT | 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 53/14 (20190201) Electric Digital Data Processing G06F 1/203 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/24 (20130101) G08B 21/182 (20130101) G08B 21/0247 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/6205 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0029 (20130101) H02J 7/0045 (20130101) Original (OR) Class Transmission H04B 17/23 (20150115) H04B 17/27 (20150115) H04B 17/318 (20150115) Telephonic Communication H04M 1/0202 (20130101) H04M 1/0262 (20130101) H04M 1/7253 (20130101) H04M 2250/12 (20130101) Wireless Communication Networks H04W 4/023 (20130101) H04W 88/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10432320 | Gorshkov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Alexey V. Gorshkov (Rockville, Maryland); Michael Foss-Feig (Baltimore, Maryland); Zachary Eldredge (Adelphi, Maryland); Zhe-Xuan Gong (College Park, Maryland); Ali Hamed Moosavian (College Park, Maryland); Jeremy T. Young (College Park, Maryland) |
| ABSTRACT | A process for generating an entangled state of a plurality of particles includes: providing the plurality of particles, the plurality of particles interacting via long range interactions; producing a first entangled state in a first particle; entangling the first particle with a second particle to form a second entangled state, wherein particles that are not in the second entangled state are remaining particles; and proceeding, starting with the second entangled state, to propagate entanglement in a logarithmic progression through the remaining particles in a recursive manner, to produce an intermediate entangled state, such that the intermediate entangled state acts as an initial entangled state for a next iteration, until a final entangled state is formed to generate the entangled state of the particles. |
| FILED | Thursday, November 02, 2017 |
| APPL NO | 15/802146 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 10/70 (20130101) H04B 10/90 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10432871 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hui Cao (New Haven, Connecticut); Brandon Redding (New Haven, Connecticut); Michael Choma (Hamden, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Hui Cao (New Haven, Connecticut); Brandon Redding (New Haven, Connecticut); Michael Choma (Hamden, Connecticut) |
| ABSTRACT | Systems and methods are provided for imaging using complex lasers. In general, a complex laser may be used as an electromagnetic source for an imaging application. The use of a lower spatial coherence configured complex laser in imaging applications may advantageously mitigate coherent artifacts in imaging such as cross-talk and speckle and improve overall image quality. Imaging applications where a complex laser may be useful include both incoherent imaging applications, such as digital light projectors and traditional microscopy, and coherent imaging applications, such as optical coherence tomography (OCT) and holography. The systems and methods provided also enable controlling the degree of spatial coherence of a complex laser. |
| FILED | Monday, April 16, 2012 |
| APPL NO | 14/110937 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/48 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/10 (20130101) H01S 3/30 (20130101) H01S 3/213 (20130101) H01S 3/0804 (20130101) H01S 5/10 (20130101) H01S 5/041 (20130101) Pictorial Communication, e.g Television H04N 5/235 (20130101) Original (OR) Class H04N 9/3161 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10433468 | Sturgis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Associated Universities, Inc. (Washington, District of Columbia) |
| ASSIGNEE(S) | Associated Universities, INC. (Washington, District of Columbia) |
| INVENTOR(S) | Silversun Sturgis (Socorro, New Mexico) |
| ABSTRACT | A modular system for containing electronic components has at least one storage bin and a plurality of Radio Frequency Interference (RFI) shielded electronics enclosures. Each RFI shielded electronics enclosure is at least one hollowed-out body; at least one hollowed-out cover, wherein the at least one hollowed-out cover is adapted to mate with the at least one hollowed-out body; and a plurality of fastening devices adapted to secure the at least one hollowed-out cover to the at least one hollowed-out body. |
| FILED | Monday, July 23, 2018 |
| APPL NO | 16/042013 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/182 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 9/0016 (20130101) Original (OR) Class H05K 9/0024 (20130101) H05K 9/0037 (20130101) H05K 9/0041 (20130101) H05K 9/0062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10426499 | Owen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington Through Its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Neil Owen (Seattle, Washington); Michael Bailey (Seattle, Washington); Oleg Sapozhinikov (Seattle, Washington) |
| ABSTRACT | During shock wave therapy, a determination is made that a kidney stone has begun to fracture, and then a progress of its fragmentation is assessed. This determination can reduce the number of shock waves used to disintegrate kidney stones, and thereby reduce dose-dependent tissue damage. The identification of fracture is possible through the detection and analysis of resonant acoustic scattering, which is the radiation caused by reverberations within a stone particle that is struck by a shock wave. The scattering frequency can provide both an indication that the kidney stone has fragmented, and an indication of the relative sizes of the fragments. Related concepts employ displacement measurements of kidney stones/fragments to provide both an indication that the kidney stone has fragmented, and an indication of the relative sizes of the fragments. Such techniques can be combined with vibro-acoustography based gating that better targets the stone. |
| FILED | Wednesday, August 14, 2013 |
| APPL NO | 13/966535 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/06 (20130101) A61B 5/4848 (20130101) A61B 7/00 (20130101) A61B 7/04 (20130101) A61B 8/00 (20130101) A61B 8/13 (20130101) A61B 8/085 (20130101) A61B 8/0833 (20130101) A61B 17/225 (20130101) A61B 17/2255 (20130101) A61B 17/2256 (20130101) A61B 17/22004 (20130101) Original (OR) Class A61B 17/22012 (20130101) A61B 17/22029 (20130101) A61B 2017/22011 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) A61N 7/02 (20130101) A61N 7/022 (20130101) A61N 2007/0052 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/0016 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/35 (20130101) G10K 15/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427461 | Padula, II et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Santo A. Padula, II (North Olmsted, Ohio); James Benzing (North canton, Ohio); Colln M. Creager (Columbia Station, Ohio) |
| ABSTRACT | A tire having a plurality of shape memory alloy (SMA) radial stiffening elements including a first end portion, a second end portion, and an arching middle portion. Each SMA radial element is secured to the rim of a wheel to form arching elements extending about an entire circumference of the tire. |
| FILED | Friday, May 19, 2017 |
| APPL NO | 15/599527 |
| ART UNIT | 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion B60B 21/104 (20130101) Vehicle Tyres Tyre Inflation; Tyre Changing or Repairing; Repairing, or Connecting Valves To, Inflatable Elastic Bodies in General; Devices or Arrangements Related to Tyres B60C 7/06 (20130101) Original (OR) Class B60C 7/14 (20130101) Alloys C22C 19/03 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10427807 | Stackpoole et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The USA as Represented by the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Margaret M. Stackpoole (Santa Clara, California); Ehson M. Ghandehari (Livermore, California); Jeremy J. Thornton (Gardena, California); Melmoth Alan Covington (San Jose, California) |
| ABSTRACT | A method for preparing a flexible low-density thermal protection material, the method comprising providing a flexible substrate and a pyrolizable material impregnated therein. The thermal protection material remains flexible after impregnation and continues to remain flexible when the pyrolizable material is fully pyrolized. |
| FILED | Thursday, March 02, 2017 |
| APPL NO | 15/448424 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428181 | Meador et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio Aerospace Institute (Brook Park, Ohio); U.S. Government, represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | OHIO AEROSPACE INSTITUTE (Brook Park, Ohio); U.S. GOVERNMENT AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (Washington, District of Columbia) |
| INVENTOR(S) | Mary Ann B. Meador (Strongsville, Ohio); Baochau N. Nguyen (North Royalton, Ohio); Haiquan Guo (Avon, Ohio) |
| ABSTRACT | Porous cross-linked partially aliphatic polyimide networks are provided. The polyimide networks comprise a polyamic acid oligomer that (i) comprises a repeating unit of a dianhydride and a diamine and terminal functional groups, (ii) has an average degree of polymerization of 10 to 70, (iii) has been cross-linked via a cross-linking agent, comprising three or more cross-linking groups, at a balanced stoichiometry of the cross-linking groups to the terminal functional groups, and (iv) has been chemically imidized to yield the porous cross-linked polyimide network. The polyimide networks are partially aliphatic based on (a) the diamine comprising a first diamine and a second diamine, wherein the first diamine comprises a linear aliphatic backbone chain, and the second diamine does not, and/or (b) the dianhydride comprising a first dianhydride and a second dianhydride, wherein the first dianhydride comprises a linear aliphatic backbone chain, and the second dianhydride does not. |
| FILED | Wednesday, October 11, 2017 |
| APPL NO | 15/729941 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 63/68 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/1007 (20130101) Original (OR) Class C08G 2101/0091 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/28 (20130101) C08J 2379/08 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0025 (20130101) C08K 5/095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428740 | Suciu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Gabriel L. Suciu (Glastonbury, Connecticut); Jesse M. Chandler (South Windsor, Connecticut) |
| ABSTRACT | A propulsion system for an aircraft has at least two fans with each fan having a fan drive shaft. A turboshaft gas turbine engine drives each of the at least two fans. The turboshaft engine drives an output shaft which drives a gear to, in turn, engage to drive a gear on a first intermediate shaft extending from the turboshaft gas turbine engine in a rearward direction toward an intermediate fan drive shaft. The intermediate fan drive shaft drives the fan drive shaft, and the at least two first intermediate drive shafts extending over a distance that is greater in an axial dimension defined between the turboshaft gas turbine engine and the fan than it is in a width dimension defined between the at least two fans. |
| FILED | Thursday, December 08, 2016 |
| APPL NO | 15/373072 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/00 (20130101) B64D 27/14 (20130101) B64D 27/16 (20130101) B64D 35/00 (20130101) B64D 2033/0293 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/36 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2250/312 (20130101) F05D 2250/313 (20130101) F05D 2250/314 (20130101) F05D 2260/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10428928 | Corallo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Roger Corallo (West Suffield, Connecticut) |
| ABSTRACT | A system has an input shaft driving a first gear and supported by at least one input shaft bearing. The first gear drives at least a second gear. The second gear drives an output shaft. The output shaft is supported by at least one output shaft bearing. A gear bearing also supports at least one of the first and second gears. Lubricant movement structure is associated with at least one of the first and second gears for moving lubricant in an axial and in a radial direction to drive the lubricant toward at least one of the shaft bearing and the gear bearing. A spacecraft is also disclosed. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 15/468482 |
| ART UNIT | 3654 — Material and Article Handling |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/60 (20130101) Gearing F16H 1/20 (20130101) F16H 57/0427 (20130101) Original (OR) Class F16H 57/0464 (20130101) F16H 57/0471 (20130101) F16H 57/0472 (20130101) F16H 57/0495 (20130101) Pistons; Cylinders; Sealings F16J 15/3232 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429243 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Anthony W. Yu (Spencerville, Maryland); Michael A. Krainak (Fulton, Maryland); Diego Janches (Tracys Landing, Maryland); Sarah L. Jones (Bowie, Maryland); Branimir Blagojevic (Ellicott City, Maryland) |
| ABSTRACT | The present invention relates an apparatus and method for measuring range-resolved atmospheric sodium temperature profiles using a space-based Lidar instrument, including a diode-pumped Q-switched self-Raman c-cut Nd:YVO4 laser with intra-cavity frequency doubling that could produce multi-watt 589 nm wavelength output. The c-cut Nd:YVO4 laser has a fundamental wavelength that is tunable from 1063-1067 nm. A continuous wave narrow linewidth diode laser is used as an injection seeder to provide single-frequency grating tunable output around 1066 nm. The injection-seeded self-Raman shifted Nd:VO4 laser is tuned across the sodium vapor D2 line at 589 nm. In one embodiment, a space-qualified frequency-doubled 9 Watt at 532 nm wavelength Nd:YVO4 laser, is utilized with a tandem interference filter temperature-stabilized fused-silica-etalon receiver and high-bandwidth photon-counting detectors. |
| FILED | Thursday, August 25, 2016 |
| APPL NO | 15/246870 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/10 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) G01N 2021/399 (20130101) G01N 2021/1793 (20130101) G01N 2201/068 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4814 (20130101) G01S 17/95 (20130101) G01S 17/102 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/042 (20130101) H01S 3/0085 (20130101) H01S 3/108 (20130101) H01S 3/109 (20130101) H01S 3/117 (20130101) H01S 3/0405 (20130101) H01S 3/0602 (20130101) H01S 3/0606 (20130101) H01S 3/0941 (20130101) H01S 3/1303 (20130101) H01S 3/1611 (20130101) H01S 3/1673 (20130101) H01S 3/08095 (20130101) H01S 3/10092 (20130101) Technologies for Adaptation to Climate Change Y02A 90/19 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10429521 | Wrbanek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Susan Y. Wrbanek (Sheffield Village, Ohio); John D. Wrbanek (Sheffield Village, Ohio); Gustave C. Fralick (Middleburg Heights, Ohio) |
| ABSTRACT | A small, low power, solid state particle counter may be configured to detect radiation. A scintillator may be doped to emit light in a predetermined energy range when impacted by radiation particles. A photodiode attached to or held against the scintillator may be configured to detect the emitted light in the predetermined energy range and output a current proportional to an amount of the emitted light. |
| FILED | Tuesday, January 20, 2015 |
| APPL NO | 14/600090 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/208 (20130101) G01T 1/2018 (20130101) Original (OR) Class G01T 1/2023 (20130101) G01T 1/2033 (20130101) G01T 1/2042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431355 | Fesmire et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | James E. Fesmire (Titusville, Florida); Adam M. Swanger (Orlando, Florida) |
| ABSTRACT | The feed-through assembly provides for the conveyance of a feed element from one boundary environment to another. The feed-through assembly includes the following components (from bottom to top) each with an axially extending aperture through which at least one feed element passes: lower compression member; packing stack including a plurality of packing buttons; and upper compression member. The plurality of packing buttons are made from expanded polytetrafluoroethylene (ePTFE) foam material (e.g., GORE-TEX®). A portion of the feed element is sealed within the packing stack including the plurality of packing buttons after it is compressed between the two compression members. The feed-through assembly is very cost effective and easy to make, but provides solutions to sealing problems under severe conditions or for extremely demanding requirements. |
| FILED | Wednesday, September 27, 2017 |
| APPL NO | 15/717021 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/427 (20130101) H01B 17/308 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431896 | Boryssenko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUVOTRONICS, INC (Radford, Virginia) |
| ASSIGNEE(S) | CUBIC CORPORATION (San Diego, California) |
| INVENTOR(S) | Anatoliy Boryssenko (Belchertown, Massachusetts); Kenneth Vanhille (Cary, North Carolina); Jennifer Arroyo (Arvada, Colorado) |
| ABSTRACT | Multiband antenna in the form of a three dimensional solid have a plurality of radiating cavities disposed therein. |
| FILED | Thursday, December 08, 2016 |
| APPL NO | 15/373016 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 5/35 (20150115) H01Q 5/40 (20150115) H01Q 5/47 (20150115) H01Q 5/50 (20150115) H01Q 13/18 (20130101) Original (OR) Class H01Q 21/28 (20130101) H01Q 21/0043 (20130101) H01Q 21/064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10432309 | Farr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | William H. Farr (Monrovia, California); Meera Srinivasan (La Crescenta, California) |
| ABSTRACT | A receiver, transmitter, and photon counting detector for use in an optical communication link are disclosed. Also disclosed are methods of communicating using the transmitter, the receiver, and the photon detector. |
| FILED | Thursday, December 06, 2018 |
| APPL NO | 16/211557 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission H04B 10/54 (20130101) H04B 10/118 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10433308 | Krasowski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of Americas as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Michael J. Krasowski (Chagrin Falls, Ohio) |
| ABSTRACT | A sensor network may be configured to operate in extreme temperature environments. A sensor may be configured to generate a frequency carrier, and transmit the frequency carrier to a node. The node may be configured to amplitude modulate the frequency carrier, and transmit the amplitude modulated frequency carrier to a receiver. |
| FILED | Friday, December 08, 2017 |
| APPL NO | 15/835927 |
| ART UNIT | 2414 — Multiplex and VoIP |
| CURRENT CPC | Wireless Communication Networks H04W 72/0453 (20130101) Original (OR) Class H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10429676 | Seyedi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Mir Ashkan Seyedi (Palo Alto, California); Chin-Hui Chen (Palo Alto, California) |
| ABSTRACT | In one example, a device includes a bus waveguide to carry a light of a carrier wavelength, a first ring waveguide with a first modulator, a first heater to adjust a resonance wavelength of the first ring waveguide, and a second ring waveguide with a second modulator. The first ring waveguide and the second ring waveguide are coupled to the bus waveguide and are to modulate the light of the carrier wavelength to impart one of at least four optical power levels to the light. In another example, a device includes, a bus waveguide, a first ring waveguide with a first modulator, and a second ring waveguide with a second modulator. The first ring waveguide and the second ring waveguide are coupled to the bus waveguide and are to modulate a light of a carrier wavelength to impart one of at least four optical power levels to the light. |
| FILED | Thursday, July 23, 2015 |
| APPL NO | 15/745712 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/287 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/0147 (20130101) Original (OR) Class G02F 2201/16 (20130101) G02F 2201/17 (20130101) G02F 2203/05 (20130101) G02F 2203/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10432315 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Janet Chen (Palo Alto, California); Cheng Li (Palo Alto, California); Marco Fiorentino (Mountain View, California); Raymond G Beausoleil (Seattle, Washington) |
| ABSTRACT | One example includes an optical transmitter system. The system includes a waveguide to receive and propagate an optical signal. The system also includes a ring modulation system comprising a ring resonator that is optically coupled to the waveguide and is to resonate a given wavelength of the optical signal in response to an input data signal that is provided to a modulation amplifier to provide carrier injection to change a refractive index of the ring resonator to resonate the given wavelength of the optical signal to modulate the optical signal. The system further includes a tuning controller associated with the ring modulation system. The tuning controller can implement iterative feedback tuning of the ring modulation system based on a relative amplitude of an optical intensity of the given wavelength in the ring resonator and a variable reference amplitude to substantially stabilize the ring resonator with respect to the given wavelength. |
| FILED | Tuesday, July 21, 2015 |
| APPL NO | 15/745709 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/29338 (20130101) G02B 6/29395 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/0121 (20130101) G02F 2201/58 (20130101) G02F 2203/15 (20130101) Transmission H04B 10/506 (20130101) H04B 10/675 (20130101) H04B 10/0799 (20130101) H04B 10/801 (20130101) H04B 10/5051 (20130101) H04B 10/25755 (20130101) H04B 10/50572 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10432319 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Kehan Zhu (Palo Alto, California); Cheng Li (Palo Alto, California); Marco Fiorentino (Mountain View, California) |
| ABSTRACT | One example of a receiver includes a first stage, a second stage, a third stage, and an automatic gain controller. The first stage amplifies an input signal to provide a first signal. The second stage amplifies or attenuates the first signal to provide a second signal based on a tunable gain of the second stage. The tunable gain is adjusted in response to a differential signal. The third stage amplifies the second signal to provide an output signal. The automatic gain controller provides the differential signal based on a comparison between a peak voltage of the output signal and the sum of a common mode voltage of the output signal and an offset voltage. |
| FILED | Thursday, October 29, 2015 |
| APPL NO | 15/768975 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/25 (20130101) H04B 10/693 (20130101) H04B 10/2507 (20130101) H04B 10/6931 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 25/4917 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10428377 | Knapp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIPER LIFE SCIENCES, Inc. (Hopkinton, Massachusetts) |
| ASSIGNEE(S) | CALIPER LIFE SCIENCES, INC. (Hopkinton, Massachusetts) |
| INVENTOR(S) | Michael R. Knapp (Palo Alto, California); Jill M. Baker (Redwood City, California); Andrea W. Chow (Los Altos, California); Anne R. Kopf-Sill (Portola Valley, California); Michael Spaid (Mountain View, California) |
| ABSTRACT | Methods are provided for detecting low copy nucleic acids of interest in a sample. In one method, a sample comprising a nucleic acid of interest is aliquotted into a plurality of reaction mixtures, at least two of which are single-copy reaction mixtures. The reaction mixtures are subjected to one or more amplification reactions while flowing through a channel of a microfluidic device. At least one of the reaction mixtures is formulated in an aqueous phase of an emulsion comprising aqueous droplets suspended in an immiscible liquid. The nucleic acid of interest is present as a single copy in at least one aqueous droplet of the aqueous phase prior to performing the amplification reaction(s). Amplification is performed on the reaction mixture when it is formulated in the emulsion. The nucleic acid is continuously flowed during a plurality of steps of the method. |
| FILED | Monday, April 14, 2014 |
| APPL NO | 14/252755 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 7/52 (20130101) B01L 2200/10 (20130101) B01L 2200/16 (20130101) B01L 2300/1827 (20130101) B01L 2400/0406 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/686 (20130101) C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 1/6851 (20130101) C12Q 1/6851 (20130101) C12Q 1/6851 (20130101) C12Q 1/6851 (20130101) C12Q 2527/143 (20130101) C12Q 2531/113 (20130101) C12Q 2531/113 (20130101) C12Q 2531/113 (20130101) C12Q 2537/157 (20130101) C12Q 2547/107 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10432320 | Gorshkov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Alexey V. Gorshkov (Rockville, Maryland); Michael Foss-Feig (Baltimore, Maryland); Zachary Eldredge (Adelphi, Maryland); Zhe-Xuan Gong (College Park, Maryland); Ali Hamed Moosavian (College Park, Maryland); Jeremy T. Young (College Park, Maryland) |
| ABSTRACT | A process for generating an entangled state of a plurality of particles includes: providing the plurality of particles, the plurality of particles interacting via long range interactions; producing a first entangled state in a first particle; entangling the first particle with a second particle to form a second entangled state, wherein particles that are not in the second entangled state are remaining particles; and proceeding, starting with the second entangled state, to propagate entanglement in a logarithmic progression through the remaining particles in a recursive manner, to produce an intermediate entangled state, such that the intermediate entangled state acts as an initial entangled state for a next iteration, until a final entangled state is formed to generate the entangled state of the particles. |
| FILED | Thursday, November 02, 2017 |
| APPL NO | 15/802146 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 10/70 (20130101) H04B 10/90 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10426398 | Lieber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Richard L. Lieber (Chicago, Illinois); Stojan Radic (San Diego, California); Kevin Young (San Diego, California) |
| ABSTRACT | Methods and systems for measuring muscle sarcomere length are disclosed. In an embodiment, a method comprises illuminating a set of muscle fibers with electromagnetic radiation, measuring an intensity of the electromagnetic radiation as reflected from the muscle fibers, the measuring occurring as a function of wavelength, determining wavelengths corresponding to maximums of reflected intensity, and correlating the determined wavelengths with respective muscle sarcomere lengths. In an embodiment, a system comprises an illumination source system for illuminating the set of muscle fibers with electromagnetic radiation, and an analyzer for measuring the intensity of the electromagnetic radiation as reflected from the muscle fibers. |
| FILED | Thursday, October 01, 2015 |
| APPL NO | 14/872906 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/0084 (20130101) A61B 5/1076 (20130101) A61B 5/1079 (20130101) A61B 5/4519 (20130101) Original (OR) Class A61B 2505/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10426872 | Sakamoto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); The United States Of America As Represented By The Department Of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey S. Sakamoto (Ann Arbor, Michigan); Dena Shahriari (Ann Arbor, Michigan); Mark H. Tuszynski (La Jolla, California); Wendy Campana (La Jolla, California); Yacov Koffler (San Diego, California) |
| ABSTRACT | Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall having a thickness of ≤about 100 μm that is formed from a biocompatible and biodegradable material comprising a polyester polymer. The polyester polymer may be polycaprolactone, poly(lactic-co-glycolic acid) polymer, and combinations thereof. The tissue scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. In other aspects, methods of making such tissue scaffolds are provided. Such a method may include mixing a reduced particle size porogen with a polymeric precursor solution. The material is cast onto a template and then can be processed, including assembly in a sheath and removal of the porogen, to form a tissue scaffold having a plurality of porous microchannels. |
| FILED | Friday, October 07, 2016 |
| APPL NO | 15/765981 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) Original (OR) Class A61L 27/58 (20130101) A61L 2300/252 (20130101) A61L 2300/412 (20130101) A61L 2430/32 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 89/00 (20130101) C08L 89/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10430728 | Snapp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert F. Snapp (Memphis, Tennessee); Michael C. Garner (Collierville, Tennessee); Edgar H. Gillock, II (Memphis, Tennessee); James D. Wilson (Collierville, Tennessee) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Robert F. Snapp (Memphis, Tennessee); Michael C. Garner (Collierville, Tennessee); Edgar H. Gillock, II (Memphis, Tennessee); James D. Wilson (Collierville, Tennessee) |
| ABSTRACT | Systems and methods are provided for determining secondary address information. In one implementation, a method is provided that uses a data processing apparatus. According to the method, a code word is created for a business name and a building default extended delivery code. A data table is searched using the code word and secondary address information is revealed when a match is found between the code word and data stored in the data table. |
| FILED | Thursday, August 30, 2012 |
| APPL NO | 13/599632 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Electric Digital Data Processing G06F 16/20 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10430753 | Felix et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Shea R. Felix (Falls Church, Virginia); Kate A. Sobel (Washington, District of Columbia); Rachel E. Clausen (Washington, District of Columbia) |
| ABSTRACT | A system and method for generating a return label for merchandise being returned from a buyer or consumer in a first country to a merchant in a second country. A name and address of a consumer in the first country desiring to return merchandise and merchant or seller information including a merchant identifier is received. An address for receiving returns for the merchant or seller in the second country is accessed based on the merchant information. One or more machine readable identifiers for use by a first country carrier and for use by a second country carrier based at least on the consumer information, and information for routing the return merchandise are generated. A return label for merchandise being returned from the consumer to the merchant is generated. The return label can include the machine readable identifiers and a customs declaration for the merchandise. |
| FILED | Thursday, December 11, 2014 |
| APPL NO | 14/568041 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/00 (20130101) G06Q 10/0831 (20130101) G06Q 10/0832 (20130101) G06Q 10/0833 (20130101) G06Q 10/0837 (20130101) Original (OR) Class G06Q 20/00 (20130101) G06Q 30/00 (20130101) G06Q 40/00 (20130101) G06Q 40/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US PP30917 | Clark et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Florida Foundation Seed Producers, Inc. (Marianna, Florida) |
| ASSIGNEE(S) | Florida Foundation Seed Producers, Inc. (Marianna, Florida) |
| INVENTOR(S) | David G. Clark (Gainesville, Florida); Adam Moseley (Gilmanton Iron Works, New Hampshire); Shannon Bly (Fort Pierce, Florida) |
| ABSTRACT | ‘UF16-23-2’ is a basil plant with vigorous upright growth habit, dark green leaf color, good lateral branching, late flowering and excellent resistance to Basil Downy Mildew (Peronospora belbahrii, BDM). It has a strong upright growth habit with excellent lateral branching which allows it to produce good quantities of high quality leaf tissue. Late flowering and BDM resistance in the greenhouse and field make this cultivar suitable for growers of fresh cut and potted basil for culinary use, and for home gardeners. |
| FILED | Monday, April 23, 2018 |
| APPL NO | 15/932769 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/258 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Federal Reserve Bank (FED)
| US 10430592 | Bowers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Federal Reserve Bank of Philadelphia (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Federal Reserve Bank of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Bradley C. Bowers (Wenonah, New Jersey); Keith Morales (Wynnewood, Pennsylvania); George C. Makin, V (Philadelphia, Pennsylvania); Abraham Vegh (Philadelphia, Pennsylvania) |
| ABSTRACT | A computing device may perform integrity checks on a closed operating system defining a preconfigured user portion and a preconfigured system portion using an integrity checking module. The integrity checking module may access parameters associated with an object stored on the system portion of the operating system. Files on the system portion may be accessed by submitting a query that comprises a file name, a file directory, and at least one parameter to the system portion of the operating system. The integrity checking module may provide an indication of a potential compromise to the integrity of the computing device based on the integrity check. The integrity check may be performed periodically and/or aperiodically. Updated integrity values may be compared against previously determined integrity values to update the integrity check. The integrity checking module may perform the integrity check using a signature function or hashing function to generate the integrity values. |
| FILED | Thursday, May 24, 2018 |
| APPL NO | 15/988769 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 10430961 | Qian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ObjectVideo Labs, LLC (Tysons, Virginia) |
| ASSIGNEE(S) | ObjectVideo Labs, LLC (Tysons, Virginia) |
| INVENTOR(S) | Gang Qian (McLean, Virginia); Yunxian Zhou (Herndon, Virginia); David Conger (Sterling, Virginia); Allison Beach (Leesburg, Virginia) |
| ABSTRACT | Methods and apparatus are disclosed for enhancing urban surface model with image data obtained from a satellite image. Three dimensional models of an urban cityscape obtained from digital surface models may comprise surface location information but lack image information associated with the cityscape, such as the color and texture of building facades. The location of the satellite at the time of recording the satellite image interest may be obtained from metadata associated with the satellite image. A 3D model of a cityscape corresponding to the satellite image may be subjected to a transformation operation to determine portions of the 3D model that are viewable from a location corresponding to the location of the satellite when taking the picture. Visible facades buildings of the 3D model may be identified and mapped to portions of the satellite image which may then be used in rendering 2D images from the 3D model. |
| FILED | Friday, December 16, 2016 |
| APPL NO | 15/382521 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/60 (20130101) Original (OR) Class G06T 15/04 (20130101) G06T 17/05 (20130101) G06T 2207/10032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10429488 | Parks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Walter J. Keller, III (Bridgeville, Pennsylvania); Jennting Timothy Hsu (Bethel Park, Pennsylvania) |
| ASSIGNEE(S) | NOKOMIS, INC. (Charleroi, Pennsylvania) |
| INVENTOR(S) | Brandon Scott Parks (South Park, Pennsylvania); Walter J. Keller, III (Bridgeville, Pennsylvania); Jennting Timothy Hsu (Bethel Park, Pennsylvania) |
| ABSTRACT | A system for identifying a real-world geographic location of an emission source emitting electromagnetic energy includes a platform configured for movement and an apparatus disposed on the platform and configured to collect and process, in a passive manner and during movement of the platform, at least a pair of successive samples of the electromagnetic energy emission and define angular and spatial coordinates of the emission source. The apparatus includes at least a pair of antennas, a receiver coupled to antennas and a processor executing a predetermined logic. |
| FILED | Monday, May 22, 2017 |
| APPL NO | 15/601391 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/46 (20130101) G01S 5/04 (20130101) Original (OR) Class G01S 5/0221 (20130101) G01S 5/0278 (20130101) G01S 5/0284 (20130101) G01S 5/0294 (20130101) G01S 19/21 (20130101) G01S 19/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. Agency for International Development (USAID)
| US 10426332 | Manquez Hatta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eyecare S.A. (Santiago, Chile) |
| ASSIGNEE(S) | Eyecare S.A. (Santiago, Chile) |
| INVENTOR(S) | Maria Eliana Manquez Hatta (Santiago, Chile); Humberto Lobos Sucarrat (Santiago, Chile) |
| ABSTRACT | A system for preliminary diagnosis of ocular diseases is proposed, in which from capturing a plurality of images of the eyes of a person, a final image, corrected by processing the images by a computer application, is obtained. The already mentioned application calculates the percentage of the colors composing the pupillary reflex of each eye, and compares the results with previous reference pictures obtained from normal cases and clinical cases of ocular diseases. |
| FILED | Wednesday, April 18, 2018 |
| APPL NO | 15/956555 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/0025 (20130101) Original (OR) Class A61B 3/112 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10430048 | Kunes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| INVENTOR(S) | David Kunes (Tisnov, Czech Republic); Zdenek Moravek (Rozdrojovice, Czech Republic); Katerina Chmelarova (Hradec Kralove, Czech Republic); Ivan Lacko (Cana, Slovakia) |
| ABSTRACT | A system and method for an improved aircraft information display is provided. The provided embodiments integrate and analyze relevant data from on-board and external sources to render airport availability and suitability information on the aircraft information display. The airport availability and suitability information displayed on the aircraft information display incorporates links between related information, is intuitively arranged on the aircraft information display, and dynamically updates responsive to changes in data and to user interaction. |
| FILED | Wednesday, August 24, 2016 |
| APPL NO | 15/245317 |
| ART UNIT | 2143 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/04842 (20130101) Original (OR) Class G06F 3/04892 (20130101) Traffic Control Systems G08G 5/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10430587 | Kuan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | George Kuan (Westlake Village, California); Aleksey Nogin (Fresno, California) |
| ABSTRACT | Described is a system and method for monitoring and enforcing information flow security in software systems. The system maintains security tags and reference counts for objects in computer memory. When an object or a portion of an object in the computer memory is being modified, the system arbitrarily performs operations of updating a security tag for the object being modified; updating reference counts for all objects that the portion of the object in the computer memory being modified pointed to immediately prior to modification; and updating reference counts for all objects that the portion of the object in the computer memory being modified points to immediately after the modification. Subsequently, the system examines the security tags and if the examination reveals a potential information flow security violation, a corrective action is performed. |
| FILED | Friday, October 28, 2016 |
| APPL NO | 15/338295 |
| ART UNIT | 2493 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/23 (20190101) G06F 21/54 (20130101) G06F 21/566 (20130101) Original (OR) Class G06F 21/577 (20130101) G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10431889 | White et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Charles Stark Draper Laboratory Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Douglas W. White (Lexington, Massachusetts); Warner G. Harrison (Medfield, Massachusetts) |
| ABSTRACT | An adaptive impedance matching network to implement an impedance match between an RF power device and an antenna comprises a matching network having at least one tunable component, a current sensor providing a current value corresponding to the supply current associated with the RF power device, a power sensor configured to provide an RF power sensor value monotonically related to power delivered to the antenna, and a tuner to provide a tuning signal to the matching network as a function of the current and RF power values. The tuner may adjust the tuning signal so that the RF power sensor value is at least as large as for other settings of the tuning signal, while maintaining the supply current at a predetermined amount corresponding to an amount of supply current occurring when the RF power device is driving a load that produces the desired RF output power and amplifier efficiency. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 15/456430 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 5/335 (20150115) Original (OR) Class Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
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THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, October 01, 2019.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20191001.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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