FedInvent™ Patents
Patent Details for Tuesday, October 08, 2019
This page was updated on Monday, March 27, 2023 at 05:55 AM GMT
Department of Health and Human Services (HHS)
| US 10433576 | Longo et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Valter D. Longo (Playa Del Rey, California); Chia-Wei Cheng (Los Angeles, California) |
| ABSTRACT | A method of alleviating symptoms of, or treating, pancreatic beta-cell damage in a subject includes a step of identifying a subject having pancreatic beta-cell damage. Multiple cycles of a diet protocol are administered to the subject. The diet protocol includes administering of a fasting mimicking diet and a re-feeding diet where the fasting mimicking diet is provided for a first time period and the re-feeding diet is provided for a second time period. |
| FILED | Thursday, July 07, 2016 |
| APPL NO | 15/204156 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/30 (20160801) Original (OR) Class A23L 33/40 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2002/00 (20130101) A23V 2200/328 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10433733 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Lihong Wang (St. Louis, Missouri); Lidai Wang (St. Louis, Missouri); Konstantin Maslov (St. Louis, Missouri) |
| ABSTRACT | A method for obtaining a 3-D OR-PAM image of microvasculature within a region of interest of a subject is provided. The method includes: focusing a first light pulse at a first depth beneath a first surface position within the region of interest; receiving a first PA signal in response to the first light pulse; focusing a second light pulse at a second depth beneath the first surface position within the region of interest; receiving a second PA signal in response to the second light pulse; and forming the 3-D OR-PAM image by combining the first PA signal and the second PA signal. |
| FILED | Friday, May 06, 2016 |
| APPL NO | 15/148685 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0059 (20130101) A61B 5/0068 (20130101) A61B 5/0082 (20130101) A61B 5/0095 (20130101) Original (OR) Class A61B 5/444 (20130101) A61B 5/02007 (20130101) A61B 5/4848 (20130101) A61B 5/14542 (20130101) A61B 5/14546 (20130101) A61B 8/485 (20130101) A61B 2090/306 (20160201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) G01N 29/0681 (20130101) G01N 29/2418 (20130101) G01N 2291/02836 (20130101) G01N 2291/02872 (20130101) Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10433742 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ming-Xiong Huang (San Diego, California); Roland R. Lee (San Diego, California) |
| ABSTRACT | Methods, systems, and devices are disclosed for implementing magnetoencephalography (MEG) source imaging. In one aspect, a method includes determining a covariance matrix based on sensor signal data in the time domain or frequency domain, the sensor signal data representing magnetic-field signals emitted by a brain of a subject and detected by MEG sensors in a sensor array surrounding the brain, defining a source grid containing source locations within the brain that generate magnetic signals, the source locations having a particular resolution, in which a number of source locations is greater than a number of sensors in the sensor array, and generating a source value of signal power for each location in the source grid by fitting the selected sensor covariance matrix, in which the covariance matrix is time-independent based on time or frequency information of the sensor signal data. |
| FILED | Tuesday, August 05, 2014 |
| APPL NO | 14/910218 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/04 (20130101) A61B 5/055 (20130101) A61B 5/04001 (20130101) A61B 5/04005 (20130101) A61B 5/04008 (20130101) Original (OR) Class A61B 5/04009 (20130101) A61B 5/7203 (20130101) A61B 5/7235 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10433754 | Nurmikko et al. |
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| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
| INVENTOR(S) | Arto V. Nurmikko (Providence, Rhode Island); Ming Yin (Providence, Rhode Island); William R. Patterson (Rehoboth, Massachusetts); Juan Aceros (Providence, Rhode Island); David A. Borton (Providence, Rhode Island); Christopher W. Bull (Rehoboth, Massachusetts); Farah Laiwalla (Providence, Rhode Island) |
| ABSTRACT | Systems and methods for providing an electrical interface to a body are provided. In one embodiment, an implantable module is disclosed, comprising: an implantable electrode array, implantable within a body and capable of providing a plurality of communication channels for communicating electrical signals detected in a body; an amplifier circuit for processing electrical signals received from the electrode array; a wireless transceiver for sending and receiving telemetry data between the amplifier circuit and a wireless receiver located outside of the body; and a sealed enclosure that houses the amplifier circuit and the wireless transmitter and is biocompatible with surrounding tissue, the enclosure having a window that is transparent to a wireless medium used by the wireless transceiver. In another embodiment, a wireless transceiver and amplifier is detachably coupled to a transcutaneous attachment device, and the implantable electrode array is electrically coupled to the interface board via the transcutaneous attachment device. |
| FILED | Monday, September 16, 2013 |
| APPL NO | 14/028178 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0017 (20130101) A61B 5/0031 (20130101) A61B 5/0478 (20130101) Original (OR) Class A61B 5/04001 (20130101) A61B 5/6864 (20130101) A61B 5/6868 (20130101) A61B 2560/045 (20130101) A61B 2576/026 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/375 (20130101) A61N 1/0531 (20130101) A61N 1/3606 (20130101) A61N 1/3758 (20130101) A61N 1/3787 (20130101) A61N 1/36064 (20130101) A61N 1/36125 (20130101) A61N 1/37217 (20130101) A61N 1/37223 (20130101) A61N 1/37229 (20130101) A61N 1/37252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10433962 | Rafiee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Nasser Rafiee (Andover, Massachusetts); Stuart MacDonald (Andover, Massachusetts); Koosha Rafiee (Andover, Massachusetts); Rany Busold (Andover, Massachusetts); Robert J. Lederman (Chevy Chase, Maryland); Toby Rogers (Bethesda, Maryland) |
| ASSIGNEE(S) | Transmural Systems LLC (Andover, Massachusetts); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Nasser Rafiee (Andover, Massachusetts); Stuart MacDonald (Andover, Massachusetts); Koosha Rafiee (Andover, Massachusetts); Rany Busold (Andover, Massachusetts); Robert J. Lederman (Chevy Chase, Maryland); Toby Rogers (Bethesda, Maryland) |
| ABSTRACT | Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An illustrative annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. An improved protective device can be placed between the annuloplasty device and an underlying coronary artery to inhibit compression of the underlying coronary artery by the annuloplasty device in the coronary sinus. In addition, the protective device can inhibit compression of the coronary artery from inside the heart, such as from a prosthetic mitral valve that exerts radially outward pressure toward the coronary artery. The annuloplasty device can also create an artificial inner ridge or retaining feature projecting into the native mitral valve region to help secure a prosthetic mitral valve. |
| FILED | Friday, October 27, 2017 |
| APPL NO | 15/796344 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0467 (20130101) A61B 17/3201 (20130101) A61B 17/320016 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2451 (20130101) Original (OR) Class A61F 2/2466 (20130101) A61F 2230/0045 (20130101) A61F 2250/0065 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/01 (20130101) A61M 2025/0175 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434074 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Bingcheng Wang (Cleveland, Ohio); Eugene Myshkin (Cleveland, Ohio); Hui Miao (Cleveland, Ohio) |
| ABSTRACT | Methods and compositions for activating an EphA receptor can be used for identifying therapeutic agents for cancer. |
| FILED | Monday, August 15, 2016 |
| APPL NO | 15/237494 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 31/166 (20130101) Original (OR) Class A61K 38/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434075 | Cox et al. |
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| FUNDED BY |
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| APPLICANT(S) | Marc B. Cox (El Paso, Texas); Jennifer Richer (Denver, Colorado) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| INVENTOR(S) | Marc B. Cox (El Paso, Texas); Jennifer Richer (Denver, Colorado) |
| ABSTRACT | Embodiments of the current invention include methods and compositions for treating breast cancer by administering an effective amount of MJC13 to a subject in need thereof. |
| FILED | Thursday, June 15, 2017 |
| APPL NO | 15/623775 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/138 (20130101) A61K 31/167 (20130101) Original (OR) Class A61K 31/337 (20130101) A61K 31/513 (20130101) A61K 31/555 (20130101) A61K 31/565 (20130101) A61K 31/675 (20130101) A61K 31/704 (20130101) A61K 31/4196 (20130101) A61K 31/5685 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434078 | Kaufman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
| INVENTOR(S) | Daniel L. Kaufman (Los Angeles, California); Jide Tian (Los Angeles, California) |
| ABSTRACT | In certain embodiments methods are provided for the therapeutic or prophylactic amelioration of one or more symptoms or disorders associated with metabolic syndrome. In various embodiments the methods involve administering to a subject in need thereof, a GABA receptor agonist, in an amount sufficient to ameliorate said one or more symptoms. In certain embodiments methods are provided for the prophylaxis or treatment of type I diabetes and related pathologies that involve the use of GABA or GABA agonists in combination with certain other compounds (e.g., one more antigens (e.g., GAD) that have a therapeutic effect in type I diabetes and/or an anti-CD3 antibody, an anti-CD20 antibody, exendin-4, and/or or a pro-insulin therapeutic). |
| FILED | Tuesday, October 17, 2017 |
| APPL NO | 15/786440 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/197 (20130101) Original (OR) Class A61K 31/197 (20130101) A61K 31/4465 (20130101) A61K 31/4465 (20130101) A61K 38/2013 (20130101) A61K 39/0008 (20130101) A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434079 | Ischiropoulos et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Harry Ischiropoulos (Media, Pennsylvania); Paschalis-Thomas Doulias (Philadelphia, Pennsylvania) |
| ABSTRACT | Compositions and methods for inhibiting, treating, and/or preventing fatty acid metabolism disorders, particularly fatty acid oxidation disorders, in a subject are provided. |
| FILED | Tuesday, July 29, 2014 |
| APPL NO | 14/907397 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) Original (OR) Class A61K 31/198 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/32 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434080 | Van Dyke et al. |
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| FUNDED BY |
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| APPLICANT(S) | Forsyth Dental Infirmary for Children (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Forsyth Dental Infirmary for Children (Cambridge, None) |
| INVENTOR(S) | Thomas E. Van Dyke (West Roxbury, Massachusetts); Hatice Hasturk (Brighton, Massachusetts); Alpdogan Kantarci (Brighton, Massachusetts) |
| ABSTRACT | The invention provides methods for increasing oral osteogenesis using LXA4 and its analogs. Methods are also provided for treating or preventing oral disorders that would benefit from increased oral osteogenesis using LXA4 and its analogs. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 14/769736 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 9/0063 (20130101) A61K 31/202 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434085 | Croatt et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Greensboro (Greensboro, North Carolina); Cedric Pearce (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | University of North Carolina at Greensboro (Greensboro, North Carolina) |
| INVENTOR(S) | Mitchell P. Croatt (Greensboro, North Carolina); Lara Fakhouri (Greensboro, North Carolina); Nicholas H. Oberlies (Greensboro, North Carolina); Cedric Pearce (Chapel Hill, North Carolina) |
| ABSTRACT | This disclosure is directed to non-aromatic difluoro analogues of resorcylic acid lactones, pharmaceutical compositions comprising non-aromatic difluoro analogues of resorcylic acid lactones, and methods of treatment comprising non-aromatic difluoro analogues of resorcylic acid lactones. |
| FILED | Friday, May 27, 2016 |
| APPL NO | 15/579251 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/336 (20130101) A61K 31/365 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Heterocyclic Compounds C07D 313/00 (20130101) C07D 493/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434089 | Lamichhane |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Gyanu Lamichhane (Towson, Maryland) |
| ABSTRACT | Described are methods of treating or preventing a bacterial infection by administering an antibacterial agent comprising a β-lactamase inhibitor and one or more carbapenem to a subject. |
| FILED | Tuesday, January 23, 2018 |
| APPL NO | 15/877762 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/407 (20130101) A61K 31/439 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434104 | Strum et al. |
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| FUNDED BY |
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| APPLICANT(S) | G1 Therapeutics, Inc. (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | G1 Therapeutics, Inc. (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Jay Copeland Strum (Hillsborough, North Carolina); John Emerson Bisi (Chapel Hill, North Carolina); Patrick Joseph Roberts (Durham, North Carolina); Francis Xavier Tavares (Durham, North Carolina) |
| ABSTRACT | This invention is in the area of improved compounds for and methods of treating selected RB-positive cancers and other Rb-positive abnormal cellular proliferative disorders while minimizing the deleterious effects on healthy cells, for example healthy Hematopoietic Stem Cells and Progenitor Cells (HSPCs), associated with current treatment modalities. In one aspect, improved treatment of select RB-positive cancers is disclosed using specific compounds disclosed herein. In certain embodiments, the compounds described herein act as highly selective and, in certain embodiments, short, transiently-acting cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors when administered to subjects. |
| FILED | Friday, August 24, 2018 |
| APPL NO | 16/112362 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/519 (20130101) A61K 31/527 (20130101) Original (OR) Class A61K 31/555 (20130101) A61K 31/5377 (20130101) A61K 31/7048 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Heterocyclic Compounds C07D 487/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434111 | Bertozzi et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Carolyn Ruth Bertozzi (Berkeley, California); Nicholas J. Agard (Berkeley, California); Jennifer A. Prescher (Berkeley, California); Jeremy Michael Baskin (Berkeley, California); Ellen May Sletten (Berkeley, California) |
| ABSTRACT | The present invention provides modified cycloalkyne compounds; and method of use of such compounds in modifying biomolecules. The present invention features a cycloaddition reaction that can be carried out under physiological conditions. In general, the invention involves reacting a modified cycloalkyne with an azide moiety on a target biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provide for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids). |
| FILED | Friday, February 12, 2016 |
| APPL NO | 15/043181 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/655 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 45/63 (20130101) C07C 45/63 (20130101) C07C 45/292 (20130101) C07C 45/292 (20130101) C07C 45/511 (20130101) C07C 45/511 (20130101) C07C 45/511 (20130101) C07C 49/457 (20130101) C07C 49/457 (20130101) C07C 49/457 (20130101) C07C 49/753 (20130101) C07C 49/753 (20130101) C07C 49/753 (20130101) C07C 57/26 (20130101) C07C 59/72 (20130101) C07C 63/66 (20130101) C07C 63/74 (20130101) C07C 69/76 (20130101) C07C 69/708 (20130101) C07C 2601/18 (20170501) Heterocyclic Compounds C07D 207/416 (20130101) C07D 207/452 (20130101) C07D 249/16 (20130101) C07D 495/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/531 (20130101) G01N 33/6803 (20130101) G01N 33/6842 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434116 | Frieman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Matthew Frieman (Hunt Valley, Maryland); Peter B. Jarhling (Gaithersburg, Maryland); Lisa E. Hensley (Frederick, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland); United States Government as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Matthew Frieman (Hunt Valley, Maryland); Peter B. Jarhling (Gaithersburg, Maryland); Lisa E. Hensley (Frederick, Maryland) |
| ABSTRACT | The present invention provides methods for treating a coronavirus infection. For example, treatment may be effected by administering a neurotransmitter inhibitor, a signaling kinase inhibitor, an estrogen receptor inhibitor, a DNA metabolism inhibitor or an anti-parasitic agent. Also provided are methods for treating a coronavirus infection in which an anti-viral drug also is administered during any of the described methods. |
| FILED | Tuesday, April 07, 2015 |
| APPL NO | 15/302915 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/13 (20130101) A61K 31/13 (20130101) A61K 31/46 (20130101) A61K 31/55 (20130101) A61K 31/138 (20130101) A61K 31/138 (20130101) A61K 31/435 (20130101) A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/522 (20130101) A61K 31/522 (20130101) A61K 31/662 (20130101) A61K 31/662 (20130101) A61K 31/675 (20130101) A61K 31/675 (20130101) A61K 31/4706 (20130101) A61K 31/4706 (20130101) A61K 31/4709 (20130101) A61K 31/5415 (20130101) A61K 31/5415 (20130101) A61K 31/7012 (20130101) A61K 31/7012 (20130101) A61K 31/7056 (20130101) A61K 31/7056 (20130101) A61K 31/7068 (20130101) Original (OR) Class A61K 31/7068 (20130101) A61K 31/7072 (20130101) A61K 31/7072 (20130101) A61K 31/7125 (20130101) A61K 31/7125 (20130101) A61K 38/21 (20130101) A61K 38/21 (20130101) A61K 38/212 (20130101) A61K 38/215 (20130101) A61K 38/217 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434134 | Chojkier et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Mario Chojkier (Del Mar, California); Martina Buck (Del Mar, California) |
| ABSTRACT | The invention is directed to peptides which inhibit phosphorylation of an amino phosphoacceptor domain of C/EBPβ and their use for treating inflammation and fibrosis. |
| FILED | Monday, April 11, 2016 |
| APPL NO | 15/570910 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0078 (20130101) A61K 38/00 (20130101) A61K 38/07 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Peptides C07K 5/1019 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434146 | Conrad |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Kirk P. Conrad (Gainesville, Florida) |
| ABSTRACT | The subject invention relates to methods for improving a subject's vasculature to normalize maternal hemodynamics, particularly in subjects attempting to conceive via assisted reproductive technologies, and comprises increasing relaxin levels in a subject or increasing any one or more of: relaxin synthesis, relaxin receptor synthesis, relaxin binding to the relaxin receptor, or relaxin receptor activity. |
| FILED | Thursday, June 02, 2016 |
| APPL NO | 15/171384 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/2221 (20130101) Original (OR) Class A61K 38/2221 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434149 | Gupta et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Anirban Sen Gupta (Cleveland, Ohio); Christa Pawlowski (Seven Hills, Ohio) |
| ABSTRACT | A method of promoting hemostasis in a subject in need thereof includes administering to the subject a biocompatible flexible nanoparticle that includes an outer surface and a plurality of peptides conjugated to the surface, wherein the peptides include a plurality of von Willebrand factor-binding peptides (VBPs), collagen-binding peptides (CBPs) and an active platelet GPM-Ma-binding peptides (GBPs). |
| FILED | Tuesday, May 02, 2017 |
| APPL NO | 15/584793 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/127 (20130101) A61K 9/1271 (20130101) A61K 9/4825 (20130101) A61K 38/00 (20130101) A61K 38/36 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 38/177 (20130101) A61K 38/1774 (20130101) A61K 47/6911 (20170801) A61K 47/6929 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 14/78 (20130101) C07K 14/705 (20130101) C07K 14/745 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434152 | Wei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Wei-Zen Wei (Grosse Pointe Farms, Michigan); Heather Gibson (Madison Heights, Michigan); Richard Jones (Fayetteville, New York); Joyce Reyes (Rochester Hills, Michigan) |
| ABSTRACT | Antigenic polypeptides of the growth factor receptor HER2, for breaking the tolerance of a host against self HER2. The antigenic polypeptides include HER2 polypeptides with single amino acid substitutions of lysine for glutamine, arginine for glutamine, or aspartic acid for asparagine. Gene expression constructs, vaccine compositions, and immunization methods including the substituted HER2 polypeptides. Methods for immunizing mammalian subjects with heterologous unsubstituted HER2 antigenic polypeptides, including polypeptides of feline and bear HER2. A diagnostic method of determining whether a mammalian subject is sufficiently immunocompetent to respond to immunotherapies directed at breaking tolerance to self HER2. |
| FILED | Thursday, February 19, 2015 |
| APPL NO | 15/120621 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/53 (20130101) A61K 2039/552 (20130101) A61K 2039/572 (20130101) A61K 2039/575 (20130101) A61K 2039/55522 (20130101) Peptides C07K 14/71 (20130101) C07K 16/32 (20130101) C07K 16/2863 (20130101) C07K 16/3015 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434155 | Okada et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Hideho Okada (Pittsburgh, Pennsylvania); Walter J. Storkus (Glenshaw, Pennsylvania) |
| ABSTRACT | The invention provides a peptide derived from the interleukin-13 receptor α2, which serves as a HLA-A2-restricted cytotoxic T lymphocyte (CTL) epitope. The invention can be used as a vaccine for glioma and can be formulated into compositions for medical or veterinary use. In addition, the invention provides the use of a peptide derived from the Eph family of tyrosine kinase receptors which can be also used as a vaccine for glioma and can be formulated into compositions for medical or veterinary use. |
| FILED | Friday, July 08, 2016 |
| APPL NO | 15/205203 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 2039/572 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/7155 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434161 | Ganta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| ASSIGNEE(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| INVENTOR(S) | Roman R. Ganta (Manhattan, Kansas); Chuanmin Cheng (Manhattan, Kansas); Arathy D. S. Nair (Manhattan, Kansas); Deborah Jaworski (Stillwater, Oklahoma); Suhasini Ganta (Manhattan, Kansas) |
| ABSTRACT | Attenuated vaccines to protect vertebrate animals and people against tick-born rickettsial, Ehrlichia and Anaplasma species infections is disclosed. Also disclosed are methods to modify the organism to achieve the desired immunity through the modification of a novel genetic region involved in pathogenesis. These compounds represent a needed vaccine against an organism causing life-threatening febrile illness in humans and animals, and also represent the potential to develop new classes of drugs targeting the gene products of genes Ech_0660, Ech_0379, and Ech_0230, and their homologs of other related rickettsial pathogens. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/106546 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0233 (20130101) Original (OR) Class A61K 2039/522 (20130101) A61K 2039/552 (20130101) A61K 2039/575 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434164 | Gale, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Michael J. Gale, Jr. (Seattle, Washington); Gretja Schnell (Seattle, Washington); Yueh-Ming Loo (Seattle, Washington) |
| ABSTRACT | Compositions and methods are provided that enable activation of innate immune responses through RIG-I like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (PAMPs) that comprise elements initially characterized in, and derived from, the hepatitis C virus genome. |
| FILED | Thursday, September 21, 2017 |
| APPL NO | 15/711934 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2039/57 (20130101) A61K 2039/555 (20130101) A61K 2039/55561 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/117 (20130101) C12N 2310/17 (20130101) C12N 2770/24134 (20130101) C12N 2770/24232 (20130101) C12N 2770/24234 (20130101) C12N 2770/24271 (20130101) Technologies for Adaptation to Climate Change Y02A 50/39 (20180101) Y02A 50/386 (20180101) Y02A 50/388 (20180101) Y02A 50/394 (20180101) Y02A 50/466 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434174 | Saha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BIOMED VALLEY DISCOVERIES, INC. (Kansas City, Missouri); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); BioMed Valley Discoveries, Inc. (Kansans City, Missouri) |
| INVENTOR(S) | Saurabh Saha (Wellesley Hills, Massachusetts); Xiaoyan M. Zhang (Lexington, Massachusetts); Dimiter Dimitrov (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland); Brad St. Croix (Frederick, Maryland); Enrique Zudaire (Germantown, Maryland) |
| ABSTRACT | Methods, pharmaceutical compositions, and kits for treating a disease, such as cancer, in a subject. The methods include: administering to a subject in need thereof (a) a therapeutically effective amount of a platinum agent; and (b) a therapeutically effective amount of a monoclonal antibody or antigen binding fragment thereof. |
| FILED | Tuesday, June 09, 2015 |
| APPL NO | 15/317084 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/282 (20130101) A61K 31/282 (20130101) A61K 31/555 (20130101) A61K 31/555 (20130101) A61K 33/24 (20130101) A61K 39/39558 (20130101) Original (OR) Class A61K 39/39558 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/22 (20130101) C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/303 (20130101) C07K 16/3015 (20130101) C07K 16/3023 (20130101) C07K 16/3046 (20130101) C07K 16/3053 (20130101) C07K 16/3069 (20130101) C07K 2317/56 (20130101) C07K 2317/72 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/732 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434177 | Bruchez et al. |
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| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Marcel P. Bruchez (Pittsburgh, Pennsylvania); Jianjun He (Pittsburgh, Pennsylvania); Yi Wang (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided herein is a two-component photosensitizer, which demonstrated robust and selective killing effects for transfected HEK cells and affibody targeted A431 cancer cells when exposed to near infrared light excitation. Free MG2I is a pure and stable fluorogen; it is easy to synthesize and modify, and has no toxicity to cells. Unlike conventional photosensitizers, the dye and FAP itself has no photosensitizing effect until they are bound. Also unlike other activation methods, the activation step is achieved by adding the fluorogen, not the presence of the targeted molecule, requiring an ‘active’ activation instead of a ‘passive’ activation. This method offers the ability to locally switch-on and selective generation of singlet oxygen at the target site and can be used for a wide variety of molecular targets. |
| FILED | Tuesday, November 17, 2015 |
| APPL NO | 15/527061 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0057 (20130101) Original (OR) Class A61K 47/64 (20170801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0659 (20130101) Acyclic or Carbocyclic Compounds C07C 211/43 (20130101) C07C 233/36 (20130101) C07C 233/40 (20130101) Peptides C07K 14/001 (20130101) C07K 14/71 (20130101) C07K 2317/622 (20130101) C07K 2319/30 (20130101) C07K 2319/035 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 11/10 (20130101) C09B 11/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434188 | Trippel et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Indiana University (Indianapolis, Indiana); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Indianapolis, Indiana); UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Stephen B. Trippel (Indianapolis, Indiana); Shuiliang Shi (Carmel, Indiana) |
| ABSTRACT | The present invention provides fusion proteins including a hyaluronic acid-binding domain of a cartilage matrix protein and a conserved region of a growth factor protein. Certain embodiments provide nucleic nucleic acid sequences encoding a fusion protein and compositions thereof. Methods for using fusion polypeptides and nucleic acid molecules discloses herein are also provided. In certain embodiments, the fusion proteins and/or nucleic acid molecules can be used to treat a cartilage matrix protein-related condition in a subject. |
| FILED | Tuesday, June 03, 2014 |
| APPL NO | 14/294305 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) Original (OR) Class Peptides C07K 14/65 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434189 | Essani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of Western Michigan University (Kalamazoo, Michigan) |
| ASSIGNEE(S) | The Board of Trustees of Western Michigan University (Kalamazoo, Michigan) |
| INVENTOR(S) | Karim Essani (Kalamazoo, Michigan); David Jeng (Kalamazoo, Michigan); Steven J. Conrad (Lansing, Michigan) |
| ABSTRACT | A composition for treating cancerous cells in a subject having an immune system includes a virus in the Yatapoxvirus genus having at least one mutation. In one embodiment, the mutation results in suppressed expression of a TNF binding protein by the virus. In another embodiment, the mutation results in suppressed expression of thymidine kinase (“TK”) by the virus. In another embodiment, the mutation arms the virus with a transgene to express a bacterial flagellin. The mutations can be present singly or in combination. Additional aspects include a method of treating cancerous cells with a composition as described herein, and a method of delivering at least one gene to cancerous cells in a subject. |
| FILED | Tuesday, January 17, 2017 |
| APPL NO | 15/407912 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/768 (20130101) A61K 39/00 (20130101) A61K 48/0066 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24032 (20130101) Technologies for Adaptation to Climate Change Y02A 50/481 (20180101) Y02A 50/483 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434195 | Shim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Hyunsuk Shim (Atlanta, Georgia); Mark M. Goodman (Atlanta, Georgia); Dinesh Shetty (Atlanta, Georgia); Hyeun Yoon Oum (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to methylsulfonamide derivatives and uses as imaging agents and other uses related to CXCR4 inhibition. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising compounds disclosed herein, derivatives, or pharmaceutically acceptable salts or prodrugs thereof. In certain embodiments, the compositions disclosed herein are used for imaging to study CXCR4 related conditions. |
| FILED | Wednesday, August 03, 2016 |
| APPL NO | 15/750086 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 51/0453 (20130101) A61K 51/0459 (20130101) A61K 51/0463 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) C07B 2200/05 (20130101) Heterocyclic Compounds C07D 249/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434319 | Narayan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); TOPERA, INC. (Menlo Park, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia); Topera, Inc. (Menlo Park, California) |
| INVENTOR(S) | Sanjiv M. Narayan (Palo Alto, California); Carey Robert Briggs (La Jolla, California); Ruchir Sehra (Scottsdale, Arizona) |
| ABSTRACT | An example system and method associated with identifying and treating a source of a heart rhythm disorder are disclosed. In accordance therewith, a spatial element associated with a region of the heart is selected. Progressive rotational activations or progressive focal activations are determined in relation to the selected spatial element over a period of time. The selecting and determining are repeated over multiple periods of time. A source parameter of rotation activations or focal activations is determined, wherein the source parameter indicates consistency of successive rotational activations or focal activations in relation to a portion of the region of the heart. The determining of a source parameter is repeated for multiple regions of the heart. Thereafter, representation of the source parameter is displayed for each of the multiple regions of the heart to identify a shape representing the source of the heart rhythm disorder. |
| FILED | Tuesday, May 02, 2017 |
| APPL NO | 15/585091 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/0422 (20130101) A61B 5/02405 (20130101) A61B 2018/00577 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2230/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/365 (20130101) A61N 1/378 (20130101) A61N 1/3622 (20130101) A61N 1/3712 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434329 | Poon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Ada Shuk Yan Poon (Redwood City, California); John S. Y. Ho (Stanford, California); Yuji Tanabe (Stanford, California); Alexander J. Yeh (Palo Alto, California); Kate L. Montgomery (Palo Alto, California); Logan Grosenick (Palo Alto, California); Emily A. Ferenczi (Palo Alto, California); Vivien Tsao (Stanford, California); Shrivats Mohan Iyer (Palo Alto, California); Scott Lee Delp (Stanford, California); Karl Deisseroth (Palo Alto, California) |
| ABSTRACT | A power transmitter is provided that can include a microwave cavity resonant at a desired operating frequency, a hexagonal mesh top to leak evanescent fields out of the cavity, and a plurality of orthogonal monopole feeds with 90 degrees phase differences creating circularly polarized waves. The power transmitter can be configured to transmit energy to a wireless device implanted in an animal passing through the evanescent fields. Implantable devices are also described which can receive wireless energy from the power transmitter and stimulate the animals (e.g., optogenetic or electrical stimulation). |
| FILED | Wednesday, March 25, 2015 |
| APPL NO | 15/306495 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0031 (20130101) A61B 2503/40 (20130101) A61B 2560/0219 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0529 (20130101) A61N 1/3605 (20130101) A61N 1/3787 (20130101) A61N 1/37205 (20130101) A61N 5/0601 (20130101) A61N 5/0622 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434507 | Abate et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Adam R. Abate (San Francisco, California); Adam R. Sciambi (San Francisco, California); Russell Cole (San Francisco, California); Zev Jordan Gartner (Pacifica, California) |
| ABSTRACT | Methods for delivering discrete entities including, e.g., cells, media or reagents to substrates are provided. In certain aspects, the methods include manipulating and/or analyzing qualities of the entities or biological components thereof. In some embodiments, the methods may be used to create arrays of microenvironments and/or for two and three-dimensional printing of tissues or structures. Systems and devices for practicing the subject methods are also provided. |
| FILED | Wednesday, October 21, 2015 |
| APPL NO | 15/520056 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 2200/0673 (20130101) B01L 2300/0645 (20130101) B01L 2300/0829 (20130101) B01L 2300/0864 (20130101) B01L 2400/086 (20130101) B01L 2400/0427 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 15/1484 (20130101) G01N 2015/149 (20130101) G01N 2015/1006 (20130101) G01N 2035/1034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434511 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Mei He (Olathe, Kansas); Yong Zeng (Olathe, Kansas); Andrew Godwin (Leawood, Kansas) |
| ABSTRACT | A microfluidic exosome profiling platform integrating exosome isolation and targeted proteomic analysis is disclosed. This platform is capable of quantitative exosomal biomarker profiling directly from 30 μL plasma samples within approximately 100 minutes with markedly enhanced sensitivity and specificity. Identification of distinct subpopulation of patient-derived exosomes is demonstrated by probing surface proteins and multiparameter analyses of intravesicular biomarkers in the selected subpopulation. The expression of IGF-1R and its phosphorylation level in non-small cell lung cancer (NSCLC) patient plasma is assessed, as a non-invasive alternative to the conventional biopsy and immunohistochemistry. The microfluidic chip, which may be fabricated of a glass substrate and a layer of poly(dimethylsiloxane), can include a first capture chamber, a second capture chamber, a serpentine microchannel, a first microchannel, a second microchannel, a sample inlet, a buffer inlet, a bead inlet, at least a first connector channel, and a reagent inlet. |
| FILED | Monday, March 16, 2015 |
| APPL NO | 15/125822 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0668 (20130101) B01L 2300/087 (20130101) B01L 2300/0816 (20130101) B01L 2300/0883 (20130101) B01L 2400/043 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5304 (20130101) G01N 33/54366 (20130101) G01N 33/54386 (20130101) G01N 33/57488 (20130101) G01N 2333/4725 (20130101) G01N 2333/4745 (20130101) G01N 2333/70596 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434513 | Beebe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David J. Beebe (Monona, Wisconsin); David J. Guckenberger, Jr. (Oconomowoc, Wisconsin); Scott M. Berry (Madison, Wisconsin); Hannah M. Pezzi (New Berlin, Wisconsin) |
| ABSTRACT | A method and microfluidic device are provided for containing a droplet having an outer surface at a predetermined location. The microfluidic device includes a plate having an upper surface and a central region communicating with the upper surface. The central region is adapted for receiving a droplet of fluid thereon. The central region includes an outer periphery that defines a first fluid constraint configured for discouraging fluid on the central region from flowing therepast. A second fluid constraint extends about the first fluid constraint. The second fluid constraint is configured for discouraging fluid flowing therepast. A third fluid constraint extends about the second fluid constraint. The third fluid constraint configured for discouraging fluid flowing therepast. |
| FILED | Wednesday, June 08, 2016 |
| APPL NO | 15/176932 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 3/5088 (20130101) Original (OR) Class B01L 3/502792 (20130101) B01L 2300/165 (20130101) B01L 2300/0819 (20130101) B01L 2300/0858 (20130101) B01L 2400/086 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/2575 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435355 | Piomelli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (Genoa, Italy) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Fondazione Istituto Italiano di Tecnologia (Genoa, Italy) |
| INVENTOR(S) | Daniele Piomelli (Irvine, California); Tiziano Bandiera (Gambolo, Italy); Rita Scarpelli (Rome, Italy) |
| ABSTRACT | Described herein, inter alia, are compositions and methods useful for inhibiting fatty acid amide hydrolase. |
| FILED | Friday, October 13, 2017 |
| APPL NO | 15/783113 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 271/56 (20130101) Original (OR) Class C07C 311/29 (20130101) C07C 317/22 (20130101) C07C 2601/04 (20170501) C07C 2601/08 (20170501) C07C 2601/14 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435357 | Schoenfisch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Novan, Inc. (Morrisville, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Novan, Inc. (Morrisville, North Carolina) |
| INVENTOR(S) | Mark Schoenfisch (Chapel Hill, North Carolina); Yuan Lu (Chapel Hill, North Carolina); Nathan Stasko (Chapel Hill, North Carolina); Jian Bao (Cary, North Carolina) |
| ABSTRACT | Provided here are nitric oxide-releasing compounds that include at least two different NO donor functional groups of the same class. In some embodiments, such nitric oxide-releasing compounds are macromolecules such as dendrimer and co-condensed silica. Pharmaceutical compositions, wound dressings, kits and methods of treatments are also provided herein. |
| FILED | Thursday, January 03, 2019 |
| APPL NO | 16/239069 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/655 (20130101) Acyclic or Carbocyclic Compounds C07C 247/10 (20130101) C07C 281/20 (20130101) Original (OR) Class C07C 291/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435371 | Tabakoff |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LOHOCLA RESEARCH CORPORATION (Evanston, Illinois) |
| ASSIGNEE(S) | LOHOCLA RESEARCH CORPORATION (Evanston, Illinois) |
| INVENTOR(S) | Boris Tabakoff (Elizabeth, Illinois) |
| ABSTRACT | Aminoquinoline compounds useful for treating chronic pain, addiction, and other conditions are provided. The aminoquinoline compound is represented by Formula (I): in which the substituents thereof are defined as set forth in the specification. |
| FILED | Thursday, September 13, 2018 |
| APPL NO | 16/130789 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) A61K 31/485 (20130101) A61K 31/616 (20130101) A61K 31/616 (20130101) A61K 31/4706 (20130101) A61K 31/4706 (20130101) A61K 33/24 (20130101) A61K 33/24 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 215/46 (20130101) C07D 215/48 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435375 | Schiltz et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Gary E. Schiltz (Naperville, Illinois); Richard J. Miller (Chicago, Illinois); Rama K. Mishra (Chicago, Illinois) |
| ABSTRACT | Provided herein are small molecule modulators of CXCR4 activity (e.g., agonists, antagonists, inverse agonists, partial agonists), and methods of use thereof (e.g., for the treatment of disease). |
| FILED | Thursday, May 05, 2016 |
| APPL NO | 15/571721 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 231/56 (20130101) Original (OR) Class C07D 401/04 (20130101) C07D 401/06 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/06 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 417/14 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435418 | Tuttle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University o (Binghamton, New York) |
| INVENTOR(S) | Susan Bane Tuttle (Vestal, New York); Ozlem Dilek (Istanbul, Turkey); Kamalika Mukherjee (Binghamton, New York) |
| ABSTRACT | A reaction method comprising combining a carbonyl-substituted arylboronic acid or ester and an α-effect amine in aqueous solution at a temperature between about −5 C to 55 C, and a pH between 2 and 8 to produce an adduct. A process is also provided comprising: contacting a boron compound having a boron atom bonded to a sp2 hybridized carbon conjugated with a cis-carbonyl, the boron having at least one labile substituent, with an α-effect amine, in a solvent for a time sufficient to form an adduct, which may proceed to further products. |
| FILED | Monday, September 11, 2017 |
| APPL NO | 15/700911 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 31/69 (20130101) A61K 2300/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 35/10 (20130101) C01B 35/146 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/02 (20130101) C07F 5/025 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Peptides C07K 14/765 (20130101) C07K 16/40 (20130101) C07K 16/2863 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435430 | Prakash et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California); Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | IONIS PHARMACEUTICALS, INC. (Carlsbad, California); THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Thazha P. Prakash (Carlsbad, California); Jiaxin Hu (Coppell, Texas); Jing Liu (Austin, Texas); Dongbo Yu (Austin, Texas); David Corey (Dallas, Texas); Eric E. Swayze (Encinitas, California) |
| ABSTRACT | Described are compounds and methods useful for the treatment and investigation of diseases and disorders associated with expanded repeat-containing RNA molecules. In certain embodiments, compounds and methods useful for the modulation of ATXN-3 pre-mRNA are described. In certain embodiments, compounds and methods useful for the modulation of ATN-1 mRNA are described. |
| FILED | Thursday, July 31, 2014 |
| APPL NO | 14/908429 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/32 (20130101) C12N 2320/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435452 | Rothenberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio) |
| INVENTOR(S) | Marc E. Rothenberg (Cincinnati, Ohio); Julie Caldwell (Cincinnati, Ohio) |
| ABSTRACT | The invention provides (CDH26)-based therapeutic agent, compositions comprising same, and methods of treating inflammatory conditions using same. |
| FILED | Wednesday, May 25, 2016 |
| APPL NO | 15/577502 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/177 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 14/4728 (20130101) C07K 2319/02 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435456 | Pluznick et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Jennifer Pluznick (Lutherville-Timonium, Maryland); Blythe Shepard (Baltimore, Maryland); Niranjana Natarajan (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to the field of protein expression. More specifically, the present invention provides compositions and methods for increasing the expression and signaling of proteins on cell surfaces. In particular embodiments, the present invention provides nucleic acids and amino acid sequences useful for improving/increasing protein expression on the cell surface. In several embodiments, the sequences are operably linked to the N-terminal end of the protein of interest. The nucleic acid sequence encoding the sequence tag and the protein can comprise part of an expression vector. The protein can be expressed with the N-terminal sequence tag. In certain embodiments, the sequences of the present invention can be used with one or more chaperone or accessory proteins. In particular embodiments, the one or more chaperone/accessory proteins are encoded by the same vector or separate vectors. In other embodiments, the chaperone/accessory proteins are encoded the same vector that encodes the protein of interest. |
| FILED | Thursday, January 29, 2015 |
| APPL NO | 15/115459 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/47 (20130101) C07K 14/705 (20130101) C07K 14/723 (20130101) Original (OR) Class C07K 14/4705 (20130101) C07K 2319/035 (20130101) C07K 2319/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435461 | Lai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York); THE GOVERNING COUNCEL OF THE UNIVERSITY OF TORONTO (Toronto, Canada); U.S. ARMY MEDICAL RESEARCH AND MATERIAL COMMAND (Fort Detrick, Maryland) |
| ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York); The Governing Council of the University of Toronto (Toronto, Canada); The Government of the United States as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Jonathan R. Lai (Dobbs Ferry, New York); Jayne F. Koellhoffer (New York, New York); Julia Frei (Bronx, New York); Kartik Chandran (Brooklyn, New York); Sachdev Sidhu (Toronto, Canada); Gang Chen (Toronto, Canada); John M. Dye (Frederick, Maryland); Samantha Zak (Frederick, Maryland) |
| ABSTRACT | The present invention addresses a need for improved treatments for filovirus infections. This invention provides an isolated humanized anti-filovirus glycoprotein pre-fusion core antibody comprising a framework region having a sequence of 95% or greater identity to a human antibody framework region. Also provided is a method of treating and/or inhibiting a filovirus infection in a subject comprising administering to the subject an amount of any of the antibodies described herein, or an amount of an antigen-binding fragment thereof. Also provided is composition comprising any of the antibodies described herein, or or an amount of an antigen-binding fragment thereof. In an embodiment, the composition comprises a pharmaceutically acceptably carrier. |
| FILED | Thursday, August 06, 2015 |
| APPL NO | 15/327857 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435469 | Goldberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Michael Solomon Goldberg (Brookline, Massachusetts); Chun Gwon Park (Suwon-si, South Korea) |
| ABSTRACT | Provided are drug delivery compositions and devices useful for the treatment and/or prevention of cancer and metastatic tumors. For example, a drug delivery device is provided that comprises a biodegradable scaffold carrying one or more anti-cancer therapeutic agents that activate the innate immune system (e.g., STING agonists) and/or the adaptive immune system (e.g., anti-PD-1 antibodies). The compositions and devices may include a cytokine (e.g., IL-15 superagonist). The drug delivery device can be implanted in the void volume of a resected tumor to prevent tumor regrowth and tumor metastasis. Also provided are methods of making the drug delivery compositions and devices as well as kits containing materials to provide the compositions and devices. |
| FILED | Thursday, November 15, 2018 |
| APPL NO | 16/192598 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 9/0024 (20130101) A61K 31/444 (20130101) A61K 31/444 (20130101) A61K 31/635 (20130101) A61K 31/635 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 35/17 (20130101) A61K 38/19 (20130101) A61K 38/19 (20130101) A61K 38/2086 (20130101) A61K 39/3955 (20130101) A61K 39/39541 (20130101) A61K 39/39541 (20130101) A61K 45/06 (20130101) A61K 47/36 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2818 (20130101) Original (OR) Class C07K 16/2878 (20130101) C07K 16/2896 (20130101) C07K 2317/75 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435679 | Chavez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Alejandro Chavez (New York, New York); Frank J. Poelwijk (Dallas, Texas); George M. Church (Brookline, Massachusetts) |
| ABSTRACT | Methods of making mutant Cas9 proteins are described. |
| FILED | Thursday, October 11, 2018 |
| APPL NO | 16/157481 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Enzymes C12Y 301/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 2333/922 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435688 | Khvorova et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Neil Aronin (Newtonville, Massachusetts); Julia Alterman (Worcester, Massachusetts) |
| ABSTRACT | This disclosure relates to novel huntingtin targets. Novel oligonucleotides for the treatment of Huntington's disease are also provided. |
| FILED | Wednesday, September 06, 2017 |
| APPL NO | 15/697120 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0085 (20130101) A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/52 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/343 (20130101) C12N 2310/344 (20130101) C12N 2310/346 (20130101) C12N 2310/3515 (20130101) C12N 2310/3517 (20130101) C12N 2310/3519 (20130101) C12N 2310/3521 (20130101) C12N 2310/3533 (20130101) C12N 2320/11 (20130101) C12N 2320/30 (20130101) C12N 2320/32 (20130101) C12N 2320/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435689 | Baltimore et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | David Baltimore (Pasadena, California); Ryan M. O'Connell (Pasadena, California); Konstantin Taganov (Pasadena, California); Mark Boldin (Pasadena, California) |
| ABSTRACT | The present disclosure relates to the finding that microRNA-155 plays a role in inflammation, hematopoiesis and myeloproliferation, and that dysregulation of microRNA-155 expression is associated with particular myeloproliferative disorders. Disclosed herein are methods and compositions for diagnosing an treating disorders, including inflammation and myeloproliferation, modulating the levels of expression of one or more genes selected from the group consisting of Cutl1, Arntl, Picalm, Jarid2, PU.1, Csf1r, HIF1α, Sla, Cepbβ, and Bach1, and the like. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 15/831839 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/56 (20130101) A61K 31/7105 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/113 (20130101) C12N 2310/141 (20130101) C12N 2320/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435708 | Mali et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Prashant G. Mali (Somerville, Massachusetts); George M. Church (Brookline, Massachusetts); Luhan Yang (Somerville, Massachusetts) |
| ABSTRACT | A method of altering a eukaryotic cell is provided including transfecting the eukaryotic cell with a nucleic acid encoding RNA complementary to genomic DNA of the eukaryotic cell, transfecting the eukaryotic cell with a nucleic acid encoding an enzyme that interacts with the RNA and cleaves the genomic DNA in a site specific manner, wherein the cell expresses the RNA and the enzyme, the RNA binds to complementary genomic DNA and the enzyme cleaves the genomic DNA in a site specific manner. |
| FILED | Friday, February 12, 2016 |
| APPL NO | 15/042515 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/01 (20130101) C12N 15/10 (20130101) C12N 15/63 (20130101) C12N 15/81 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 15/87 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/907 (20130101) C12N 15/1024 (20130101) C12N 15/8201 (20130101) C12N 2800/80 (20130101) C12N 2810/55 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435710 | Guye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Patrick Guye (Cambridge, Massachusetts); Ron Weiss (Newton, Massachusetts); Mohammad Reza Ebrahimkhani (Somerville, Massachusetts) |
| ABSTRACT | Aspects of the present disclosure are directed to methods and compositions for the production of heterogeneous tissue from human induced pluripotent stem (hiPS) cells. |
| FILED | Tuesday, May 09, 2017 |
| APPL NO | 15/590209 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/4705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 2510/00 (20130101) C12N 2799/027 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435712 | Rose et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | John Rose (Guilford, Connecticut); Nina Rose (Guilford, Connecticut) |
| ABSTRACT | The present invention relates to the discovery of a high titer hybrid-virus vector that gives rise to high titer virus like vesicles (VLVs) that can be used as a vaccine. The invention includes compositions and methods of generating an evolved hybrid-virus vector vaccine and selecting high titer VLVs, methods of treating and/or preventing or immunizing against, a specific disease or disorder, and methods of inducing a memory T cell and B cell immune response in a subject administered the VLV composition produced thereby. Furthermore, the invention encompasses a pharmaceutical composition for vaccinating a subject as well as a high titer protein expression system. |
| FILED | Monday, May 11, 2015 |
| APPL NO | 15/305237 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 2039/57 (20130101) A61K 2039/545 (20130101) A61K 2039/5256 (20130101) A61K 2039/5258 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2760/20245 (20130101) C12N 2770/36122 (20130101) C12N 2770/36134 (20130101) C12N 2770/36151 (20130101) C12N 2810/6081 (20130101) C12N 2840/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435740 | Kladde et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Michael P. Kladde (Newberry, Florida); Nancy H. Nabilsi (Gainesville, Florida); Carolina E. Pardo (Pacifica, California) |
| ABSTRACT | The subject invention pertains to a method of determining methylation state and chromatin structure of target loci. The method comprises treating the genetic material obtained from the cells with DNA methyltransferase, capturing target genetic loci using a set of oligonucleotides, ligating the target loci with oligonucleotide patches that flank the target loci, treating the target loci flanked by oligonucleotide patches with bisulfite, optionally amplifying the target loci by polymerase chain reaction, sequencing the PCR products, and analyzing the sequences to determine methylation state and chromatin structure of the target loci. The current invention also provides a method to identify genes associated with a disease. The invention also provides a method to detect cells suffering from a disease in a group of cells. The current invention also provides kits suitable for carrying out the method of determining methylation state and chromatin structure of the target loci. |
| FILED | Tuesday, April 01, 2014 |
| APPL NO | 14/773826 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) C12Q 1/6858 (20130101) Original (OR) Class C12Q 1/6858 (20130101) C12Q 1/6886 (20130101) C12Q 2521/125 (20130101) C12Q 2523/125 (20130101) C12Q 2525/191 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435747 | LaBaer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joshua LaBaer (Chandler, Arizona); Kristin Gillis (Mesa, Arizona); Garrick Wallstrom (Mesa, Arizona); Jin Park (Phoenix, Arizona); Vel Murugan (Chandler, Arizona); Mitch Magee (Chandler, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Joshua LaBaer (Chandler, Arizona); Kristin Gillis (Mesa, Arizona); Garrick Wallstrom (Mesa, Arizona); Jin Park (Phoenix, Arizona); Vel Murugan (Chandler, Arizona); Mitch Magee (Chandler, Arizona) |
| ABSTRACT | Disclosed herein are compositions and methods for accurately estimating the absorbed dose of radiation indicated by a subject based on the expression pattern of a panel of radiation-modulated (RM) genes at various time points following exposure of the subject to ionizing radiation. |
| FILED | Tuesday, August 11, 2015 |
| APPL NO | 14/823433 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2537/165 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435757 | Totary-Jain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hana Totary-Jain (Wesley Chapel, Florida); Ezinne Francess Mong (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Hana Totary-Jain (Wesley Chapel, Florida); Ezinne Francess Mong (Tampa, Florida) |
| ABSTRACT | Provided herein are methods of measuring C19MC miRNA amount and/or expression in a post-natal cell and/or tissue. Provided herein are methods of measuring CpG methylation of the upstream C19MC miRNA promoter region in a post-natal cell and/or tissue. Also provided herein are methods of treating a cell, population thereof, and/or a subject in need thereof by administering a C19MC miRNA inhibitor or CRISPR to suppress the expression of specific miRNA within the C19MC or the entire C19MC cluster, population thereof, and/or the subject in need thereof. |
| FILED | Thursday, June 15, 2017 |
| APPL NO | 15/623832 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436615 | Agarwal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Yuvraj Agarwal (Pittsburgh, Pennsylvania); Christopher Harrison (Pittsburgh, Pennsylvania); Gierad Laput (Pittsburgh, Pennsylvania); Sudershan Boovaraghavan (Pittsburgh, Pennsylvania); Chen Chen (Pittsburgh, Pennsylvania); Abhijit Hota (Pittsburgh, Pennsylvania); Bo Robert Xiao (Pittsburgh, Pennsylvania); Yang Zhang (Pittsburgh, Pennsylvania) |
| ABSTRACT | A sensing system includes a sensor assembly that is communicably connected to a computer system, such as a server or a cloud computing system. The sensor assembly includes a plurality of sensors that sense a variety of different physical phenomena. The sensor assembly featurizes the raw sensor data and transmits the featurized data to the computer system. Through machine learning, the computer system then trains a classifier to serve as a virtual sensor for an event that is correlated to the data from one or more sensor streams within the featurized sensor data. The virtual sensor can then subscribe to the relevant sensor feeds from the sensor assembly and monitor for subsequent occurrences of the event. Higher order virtual sensors can receive the outputs from lower order virtual sensors to infer nonbinary details about the environment in which the sensor assemblies are located. |
| FILED | Tuesday, April 24, 2018 |
| APPL NO | 15/961537 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/00 (20130101) G01D 9/005 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/2823 (20130101) H04L 67/12 (20130101) Wireless Communication Networks H04W 4/38 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436650 | Maurer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Peter Christian Maurer (Boston, Massachusetts); Hyun Ji Noh (Boston, Massachusetts); Georg Kucsko (Cambridge, Massachusetts); Mikhail D. Lukin (Cambridge, Massachusetts); Hongkun Park (Lexington, Massachusetts); Minako Kubo (Cambridge, Massachusetts) |
| ABSTRACT | An approach to nanoscale thermometry that utilizes coherent manipulation of the electronic spin associated with nitrogen-vacancy (NV) color centers in diamond is disclosed. The methods and apparatus allow for detection of temperature variations down to milli-Kelvin resolution, at nanometer length scales. This biologically compatible approach to thermometry offers superior temperature sensitivity and reproducibility with a reduced measurement time. The disclosed apparatus can be used to study heat-generating intracellular processes. |
| FILED | Tuesday, April 01, 2014 |
| APPL NO | 14/781382 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/32 (20130101) Original (OR) Class G01K 11/20 (20130101) G01K 13/00 (20130101) G01K 2211/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436747 | Lieber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Charles M. Lieber (Lexington, Massachusetts); Ping Xie (Needham, Massachusetts) |
| ABSTRACT | There is provided a method for sensing the translocation of a molecule through a nanopore. In the method, there is directed to an inlet of a nanopore a molecule that is disposed in a first ionic solution of a first ionic concentration. The molecule is caused to translocate through the nanopore from the inlet of the nanopore to an outlet of the nanopore and into a second ionic solution of a second ionic concentration that is different than the first ionic concentration. An electrical potential, local to that ionic solution, of the first and second ionic solutions, which has a lower ionic concentration, is measured while the molecule is caused to translocate through the nanopore. |
| FILED | Wednesday, June 07, 2017 |
| APPL NO | 15/616225 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) Original (OR) Class G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436771 | Anchang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Benedict Anchang (Stanford, California); Sylvia K. Plevritis (Menlo Park, California) |
| ABSTRACT | Systems and methods for targeted therapy based on single-cell stimulus perturbation response. In one embodiment, a method for optimizing stimulus combinations for therapy includes receiving a cell sample, treating the cell sample with a plurality of stimuli by treating a different portion of the cell sample with one of the plurality of stimuli for each of the plurality of stimuli, labeling the cell sample with a plurality of metal-conjugated probes, analyzing the cell sample using a mass spectrometer, obtaining mass spectrometry data from the mass spectrometer, identifying subpopulations within the cell sample using the mass spectrometry data, computing stimulus effects, generating a nested-effects model using the mass spectrometry data, and scoring stimuli combinations using the computing device, wherein the stimulus combinations are combinations made from the plurality of stimuli. |
| FILED | Wednesday, April 05, 2017 |
| APPL NO | 15/480327 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Original (OR) Class G01N 33/6848 (20130101) G01N 33/56966 (20130101) Electric Digital Data Processing G06F 19/325 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 45/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436784 | Blakely et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Meso Scale Technologies, LLC (Rockville, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | Meso Scale Technologies, LLC (Rockville, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | William F Blakely (Silver Spring, Maryland); Eli N. Glezer (Del Mar, California); John Kenten (Boyds, Maryland); Sudeep Kumar (Gaithersburg, Maryland); Anu Mathew (North Potomac, Maryland); Natalia I. Ossetrova (Silver Spring, Maryland); George Sigal (Rockville, Maryland) |
| ABSTRACT | The present invention relates to methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. The invention also relates to algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure. |
| FILED | Tuesday, September 15, 2015 |
| APPL NO | 14/854514 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 33/6893 (20130101) G01N 33/56972 (20130101) Original (OR) Class G01N 2333/70535 (20130101) G01N 2333/70578 (20130101) G01N 2800/40 (20130101) G01N 2800/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436789 | Branch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Andrea Branch (New York, New York); Francis Eng (New York, New York) |
| ABSTRACT | The present disclosure relates to hepatitis C virus (HCV) core and minicore-binding molecules and nucleic acid sequences encoding such molecules. In particular embodiments, the present invention provides HCV core and minicore-binding molecules (e.g., monoclonal antibodies or antibody fragments) with particular light chain and/or heavy chain CDRs (e.g., selected from SEQ ID NOS: 2-4 and 6-8) and methods for using such molecules to detect the presence of HCV core proteins (e.g., mature p21 core protein or minicore proteins) in a sample. |
| FILED | Thursday, December 20, 2018 |
| APPL NO | 16/227104 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/109 (20130101) C07K 2317/34 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5767 (20130101) Original (OR) Class G01N 2333/186 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436793 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Hui Zhang (Ellicott City, Maryland); Xingde Li (Ellicott City, Maryland); Shadi Toghi Eshghi (Baltimore, Maryland) |
| ABSTRACT | The presently disclosed subject matter provides methods using mass spectrometry for direct profiling of N-linked glycans from a biological sample. In addition, the embodiments of the present invention also disclose novel methods, known as targeted analyte detection (TAD), for improving the detection limit of MALDI-MS. These methods take advantage of the carrier effect of the added standard analytes, which occurs due to the generic sigmoidal shape of the calibration curve. The functionality of TAD depends on the relative enhancement of sensitivity over the increase of the standard deviation at the analysis of target analytes with spiking in exogenous concentration. At certain ranges of exogenous concentration, the increment in the sensitivity overcomes the standard deviation, resulting in an improved LOD. Theoretically, exogenous concentrations approximately at 1 LODorig would generate the optimum LOD improvement. TAD is a cost-effective LOD improvement method, which is not limited to a certain group of analytes, or detection methods or instruments. It can be applied to enhance the detection of any analyte with different detection methods, provided that the analyte of interest can be extracted or is available in synthetic form. |
| FILED | Thursday, September 14, 2017 |
| APPL NO | 15/704252 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6842 (20130101) Original (OR) Class G01N 33/6851 (20130101) G01N 2400/12 (20130101) G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436795 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Institute for Cancer Research (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Hong Cheng (Philadelphia, Pennsylvania); Heinrich Roder (Philadelphia, Pennsylvania) |
| ABSTRACT | Carbon-detected NMR is well-suited for mapping binding sites in intrinsically disordered regions of a polypeptides, and for mapping of binding motifs in intrinsically disordered regions with single-residue resolution. Provided are methods of carbon-detected NMR for determining the amino acids that mediate the interaction between an intrinsically disordered polypeptide or protein, or an intrinsically disordered region of a polypeptide, and a biomolecule such as another polypeptide or a nucleic acid. |
| FILED | Thursday, September 14, 2017 |
| APPL NO | 15/704852 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/088 (20130101) G01N 33/6854 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436796 | Steyaert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIB VZW (Ghent, Belgium); Vrije Universiteit Brussel (Brussels, Belgium); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California); VIB VZW (Ghent, Belgium); VRIJE UNIVERSITEIT BRUSSEL (Brussels, Belgium) |
| INVENTOR(S) | Jan Steyaert (Beersel, Belgium); Els Pardon (Wezemaal, Belgium); Soren G. F. Rasmussen (Frederiksberg, Denmark); Juan Jose Fung (San Jose, California); Brian Kobilka (Palo Alto, California); Toon Laeremans (Dworp, Belgium) |
| ABSTRACT | The present invention relates to the field of GPCR structure biology and signaling. In particular, the present invention relates to protein binding domains directed against or capable of specifically binding to a functional conformational state of a G-protein-coupled receptor (GPCR). More specifically, the present invention provides protein binding domains that are capable of increasing the stability of a functional conformational state of a GPCR, in particular, increasing the stability of a GPCR in its active conformational state. The protein binding domains of the present invention can be used as a tool for the structural and functional characterization of G-protein-coupled receptors bound to various natural and synthetic ligands, as well as for screening and drug discovery efforts targeting GPCRs. Moreover, the invention also encompasses the diagnostic, prognostic and therapeutic usefulness of these protein binding domains for GPCR-related diseases. |
| FILED | Friday, October 26, 2018 |
| APPL NO | 16/172191 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) C07K 14/723 (20130101) C07K 16/28 (20130101) C07K 2317/22 (20130101) C07K 2317/33 (20130101) C07K 2317/51 (20130101) C07K 2317/56 (20130101) C07K 2317/75 (20130101) C07K 2317/569 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20 (20130101) G01N 33/68 (20130101) G01N 33/566 (20130101) G01N 33/6857 (20130101) G01N 33/6872 (20130101) Original (OR) Class G01N 2333/726 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436866 | Bilgic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Berkin Bilgic (Boston, Massachusetts); Kawin Setsompop (Charlestown, Massachusetts); Lawrence L. Wald (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for simultaneous multislice (“SMS”} magnetic resonance imaging (“MRI”}, in which a random blip gradient encoding scheme is utilized to impart a different phase to each of a plurality of different slice locations. Because of the random blip gradient encoding, the amount of the imparted phase is randomized for each phase encoding step in a Cartesian k-space trajectory. This data acquisition strategy leads to incoherent aliasing artifacts across the simultaneously excited slices. Images of the individual slices can be reconstructed using a compressed sensing framework. |
| FILED | Friday, January 30, 2015 |
| APPL NO | 15/114999 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4822 (20130101) G01R 33/4835 (20130101) Original (OR) Class G01R 33/5611 (20130101) G01R 33/5616 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436871 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Debiao Li (South Pasadena, California); Anthony G. Christodoulou (Los Angeles, California); Jaime Shaw (Los Angeles, California); Yibin Xie (Studio City, California); Christopher Nguyen (Hollywood, California) |
| ABSTRACT | A new low rank tensor (LRT) imaging strategy/methodology, specifically for quantitative cardiovascular magnetic resonance (CMR) multitasking, includes performing a low-rank tensor image model exploiting image correlation along multiple physiological and physical time dimensions, a non-ECG data acquisition strategy featuring minimal gaps in acquisition and frequent collection of auxiliary subspace training data, and a factored tensor reconstruction approach which enforces the LRT model. |
| FILED | Monday, April 24, 2017 |
| APPL NO | 15/495588 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/32 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/56 (20130101) Original (OR) Class G01R 33/561 (20130101) G01R 33/5602 (20130101) G01R 33/5613 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/00 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/36 (20130101) G06K 9/3233 (20130101) G06K 9/6249 (20130101) G06K 9/6256 (20130101) G06K 2209/051 (20130101) Image Data Processing or Generation, in General G06T 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438346 | Nadeau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kyle Nadeau (Irvine, California); Anthony J. Durkin (Irvine, California); Bruce J. Tromberg (Irvine, California) |
| ABSTRACT | The present invention relates to methods and devices that may be used to extract spatial frequency information. In one embodiment, the invention provides an instrument configured to extract data using a two-dimensional (2D) Hilbert transform technique, and providing spatial frequency information from a sample. In another embodiment, the invention provides a spatial frequency domain imaging (SFDI) device adapted for demodulation using two or less imaging frames. |
| FILED | Tuesday, January 06, 2015 |
| APPL NO | 15/108279 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/06 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/25 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4604 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/42 (20170101) G06T 7/50 (20170101) G06T 7/521 (20170101) G06T 2207/10068 (20130101) G06T 2207/30004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438560 | Rosen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Sarah Rosen (Hoboken, New Jersey); Denis G. Pelli (New York, New York) |
| ABSTRACT | Methods, systems, and apparatuses, including computer programs encoded on computer readable media, for modifying displayed text in a gaze-contingent way to reduce crowding, thus increasing the observer's visual span, and thus increasing the observer's reading rate. The trick is to introduce only a few differences between characters (not enough to produce a pattern) of text so as to reduce crowding. For example, differences between characters near the left and right extremes of the observer's estimated visual span can be altered to reduce crowding. |
| FILED | Monday, June 05, 2017 |
| APPL NO | 15/614573 |
| ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 3/013 (20130101) G06F 17/214 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0061 (20130101) Image Data Processing or Generation, in General G06T 7/73 (20170101) G06T 2207/10048 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 5/02 (20130101) Original (OR) Class G09G 5/26 (20130101) G09G 2320/0666 (20130101) G09G 2354/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438603 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Edward F. Chang (San Francisco, California); Kristofer E. Bouchard (Oakland, California) |
| ABSTRACT | Provided are methods of decoding speech from the brain of a subject. The methods include detecting speech production signals from electrodes operably coupled to the speech motor cortex of a subject while the subject produces or imagines producing a speech sound. The methods further include deriving a speech production signal pattern from the detected speech production signals, and correlating the speech production signal pattern with a reference speech production signal pattern to decode speech from the brain of the subject. Speech communication systems and devices for practicing the subject methods are also provided. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 15/905378 |
| ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/726 (20130101) A61B 5/04001 (20130101) A61B 5/4076 (20130101) A61B 5/4094 (20130101) A61B 5/4803 (20130101) A61B 5/7203 (20130101) A61B 5/7257 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 21/00 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 13/043 (20130101) G10L 15/24 (20130101) G10L 21/00 (20130101) Original (OR) Class G10L 25/03 (20130101) G10L 25/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438686 | Yao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Mylene W. M. Yao (Stanford, California); Wing H. Wong (Stanford, California) |
| ABSTRACT | Methods and computer-based systems for facilitating assessment of clinical infertility are provided. The methods and systems can be implemented to, for example, facilitate assessment of a subject for an in vitro fertilization treatment cycle, including determining probability of a live birth event. The methods and systems can be implemented to, for example, facilitate a determination of success implantation of embryos, selection of an optimal number of embryos to transfer, and determination of success in subsequent in vitro fertilization treatment cycles following an unsuccessful treatment cycle. |
| FILED | Friday, August 19, 2016 |
| APPL NO | 15/242215 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/425 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Electric Digital Data Processing G06F 19/325 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class G16B 20/00 (20190201) G16B 25/00 (20190201) G16B 40/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) Technologies for Adaptation to Climate Change Y02A 90/22 (20180101) Y02A 90/26 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10433754 | Nurmikko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
| INVENTOR(S) | Arto V. Nurmikko (Providence, Rhode Island); Ming Yin (Providence, Rhode Island); William R. Patterson (Rehoboth, Massachusetts); Juan Aceros (Providence, Rhode Island); David A. Borton (Providence, Rhode Island); Christopher W. Bull (Rehoboth, Massachusetts); Farah Laiwalla (Providence, Rhode Island) |
| ABSTRACT | Systems and methods for providing an electrical interface to a body are provided. In one embodiment, an implantable module is disclosed, comprising: an implantable electrode array, implantable within a body and capable of providing a plurality of communication channels for communicating electrical signals detected in a body; an amplifier circuit for processing electrical signals received from the electrode array; a wireless transceiver for sending and receiving telemetry data between the amplifier circuit and a wireless receiver located outside of the body; and a sealed enclosure that houses the amplifier circuit and the wireless transmitter and is biocompatible with surrounding tissue, the enclosure having a window that is transparent to a wireless medium used by the wireless transceiver. In another embodiment, a wireless transceiver and amplifier is detachably coupled to a transcutaneous attachment device, and the implantable electrode array is electrically coupled to the interface board via the transcutaneous attachment device. |
| FILED | Monday, September 16, 2013 |
| APPL NO | 14/028178 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0017 (20130101) A61B 5/0031 (20130101) A61B 5/0478 (20130101) Original (OR) Class A61B 5/04001 (20130101) A61B 5/6864 (20130101) A61B 5/6868 (20130101) A61B 2560/045 (20130101) A61B 2576/026 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/375 (20130101) A61N 1/0531 (20130101) A61N 1/3606 (20130101) A61N 1/3758 (20130101) A61N 1/3787 (20130101) A61N 1/36064 (20130101) A61N 1/36125 (20130101) A61N 1/37217 (20130101) A61N 1/37223 (20130101) A61N 1/37229 (20130101) A61N 1/37252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434030 | Asbeck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Alan T. Asbeck (Blacksburg, Virginia); Ye Ding (Cambridge, Massachusetts); Ignacio Galiana Bujanda (Cambridge, Massachusetts); Sangjun Lee (Cambridge, Massachusetts); Diana A. Wagner (Somerville, Massachusetts); Conor J. Walsh (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for providing assistance with human motion, including hip and ankle motion, are disclosed. Sensor feedback is used to determine an appropriate profile for actuating a wearable robotic system to deliver desired joint motion assistance. Variations in user kinetics and kinematics, as well as construction, materials, and fit of the wearable robotic system, are considered in order to provide assistance tailored to the user and current activity. |
| FILED | Saturday, September 19, 2015 |
| APPL NO | 15/511894 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/01 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0262 (20130101) A61H 1/0266 (20130101) A61H 3/00 (20130101) Original (OR) Class A61H 2003/007 (20130101) A61H 2201/165 (20130101) A61H 2201/501 (20130101) A61H 2201/503 (20130101) A61H 2201/1659 (20130101) A61H 2201/1695 (20130101) A61H 2201/5038 (20130101) A61H 2201/5061 (20130101) A61H 2201/5069 (20130101) A61H 2201/5071 (20130101) A61H 2201/5079 (20130101) A61H 2201/5084 (20130101) A61H 2201/5097 (20130101) A61H 2205/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434069 | Tang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yi Tang (San Gabriel, California); Zhen Gu (Los Angeles, California); Yunfeng Lu (Culver City, California); Ming Yan (Los Angeles, California); Anuradha Biswas (Los Angeles, California); Guoping Fan (Agoura Hills, California) |
| ABSTRACT | A method for intracellular delivery of single proteins or other cargo molecules by encapsulation within nanocapsules formed by interfacial polymerization of one or more types of monomers and selected protease cleavable cross-linkers is provided. The thin positively charged capsules are readily brought into the cytosol of target cells by endocytosis. The capsules are degraded by the action of endogenous proteases or co-delivered proteases on the cross-linkers releasing the functional cargo unaltered. The cross-linkers can be adapted to be cleavable by specific enzymes selected from available intracellular enzymes within the target cell or co-delivered or self-cleaving when the cargo itself is a protease. The nanocapsules produced by the methods have been shown to have long-term stability, high cell penetration capability, low toxicity and efficient protease-modulated specific degradability without affecting cargo protein function. |
| FILED | Friday, February 26, 2016 |
| APPL NO | 15/054470 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5138 (20130101) A61K 9/5169 (20130101) Original (OR) Class A61K 9/5192 (20130101) A61K 31/7088 (20130101) A61K 38/02 (20130101) A61K 41/0042 (20130101) A61K 47/58 (20170801) A61K 48/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434074 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Bingcheng Wang (Cleveland, Ohio); Eugene Myshkin (Cleveland, Ohio); Hui Miao (Cleveland, Ohio) |
| ABSTRACT | Methods and compositions for activating an EphA receptor can be used for identifying therapeutic agents for cancer. |
| FILED | Monday, August 15, 2016 |
| APPL NO | 15/237494 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 31/166 (20130101) Original (OR) Class A61K 38/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434075 | Cox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marc B. Cox (El Paso, Texas); Jennifer Richer (Denver, Colorado) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| INVENTOR(S) | Marc B. Cox (El Paso, Texas); Jennifer Richer (Denver, Colorado) |
| ABSTRACT | Embodiments of the current invention include methods and compositions for treating breast cancer by administering an effective amount of MJC13 to a subject in need thereof. |
| FILED | Thursday, June 15, 2017 |
| APPL NO | 15/623775 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/138 (20130101) A61K 31/167 (20130101) Original (OR) Class A61K 31/337 (20130101) A61K 31/513 (20130101) A61K 31/555 (20130101) A61K 31/565 (20130101) A61K 31/675 (20130101) A61K 31/704 (20130101) A61K 31/4196 (20130101) A61K 31/5685 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434152 | Wei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Wei-Zen Wei (Grosse Pointe Farms, Michigan); Heather Gibson (Madison Heights, Michigan); Richard Jones (Fayetteville, New York); Joyce Reyes (Rochester Hills, Michigan) |
| ABSTRACT | Antigenic polypeptides of the growth factor receptor HER2, for breaking the tolerance of a host against self HER2. The antigenic polypeptides include HER2 polypeptides with single amino acid substitutions of lysine for glutamine, arginine for glutamine, or aspartic acid for asparagine. Gene expression constructs, vaccine compositions, and immunization methods including the substituted HER2 polypeptides. Methods for immunizing mammalian subjects with heterologous unsubstituted HER2 antigenic polypeptides, including polypeptides of feline and bear HER2. A diagnostic method of determining whether a mammalian subject is sufficiently immunocompetent to respond to immunotherapies directed at breaking tolerance to self HER2. |
| FILED | Thursday, February 19, 2015 |
| APPL NO | 15/120621 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/53 (20130101) A61K 2039/552 (20130101) A61K 2039/572 (20130101) A61K 2039/575 (20130101) A61K 2039/55522 (20130101) Peptides C07K 14/71 (20130101) C07K 16/32 (20130101) C07K 16/2863 (20130101) C07K 16/3015 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434167 | Alving et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Carl R. Alving (Bethesda, Maryland); Zoltan Beck (Rockville, Maryland) |
| ABSTRACT | Provided herein is an adjuvant formulation comprising a monophosphoryl lipid A (MPLA)-containing liposome composition to saponin (e.g., QS-21), wherein the liposome composition comprises i) a lipid bilayer comprising phospholipids in which the hydrocarbon chains have a melting temperature in water of ≥23° C. and ii) cholesterol at a mole percent concentration of greater than about 50% (mol/mol), preferably about 55% to about 71% (mol/mol), or more preferably about 55% (mol/mol). The adjuvant formulation displays minimal toxicity of either lipid A or saponin. |
| FILED | Wednesday, March 25, 2015 |
| APPL NO | 15/127081 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/55555 (20130101) A61K 2039/55572 (20130101) A61K 2039/55577 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16034 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434194 | Basilion et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERISTY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | James R. Basilion (Shaker Heights, Ohio); Agata Exner (Westlake, Ohio); Xinning Wang (Cleveland, Ohio); Christopher Hernandez (Cleveland, Ohio) |
| ABSTRACT | A PSMA targeted nanobubble includes a membrane that defines at least one internal void, which includes at least one gas, and at least one PSMA ligand coupled or conjugated to the membrane. The membrane includes at least one lipid and at least one nonionic triblock copolymer that is effective to control the size of the nanobubble without compromising in vitro and in vivo echogenicity of the nanobubble. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 15/691407 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/481 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/223 (20130101) Original (OR) Class A61K 49/227 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 2650/58 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/21 (20130101) Compositions of Macromolecular Compounds C08L 33/26 (20130101) C08L 71/08 (20130101) C08L 2201/06 (20130101) C08L 2203/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434507 | Abate et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Adam R. Abate (San Francisco, California); Adam R. Sciambi (San Francisco, California); Russell Cole (San Francisco, California); Zev Jordan Gartner (Pacifica, California) |
| ABSTRACT | Methods for delivering discrete entities including, e.g., cells, media or reagents to substrates are provided. In certain aspects, the methods include manipulating and/or analyzing qualities of the entities or biological components thereof. In some embodiments, the methods may be used to create arrays of microenvironments and/or for two and three-dimensional printing of tissues or structures. Systems and devices for practicing the subject methods are also provided. |
| FILED | Wednesday, October 21, 2015 |
| APPL NO | 15/520056 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 2200/0673 (20130101) B01L 2300/0645 (20130101) B01L 2300/0829 (20130101) B01L 2300/0864 (20130101) B01L 2400/086 (20130101) B01L 2400/0427 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 15/1484 (20130101) G01N 2015/149 (20130101) G01N 2015/1006 (20130101) G01N 2035/1034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434542 | Dai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Xianming Dai (University Park, Pennsylvania); Birgitt M. Boschitsch (University Park, Pennsylvania); Jing Wang (University Park, Pennsylvania); Tak-Sing Wong (University Park, Pennsylvania); Nan Sun (University Park, Pennsylvania) |
| ABSTRACT | Substrates having a textured surface that can maintain or improve droplet mobility in both the Cassie and Wenzel states include a textured surface and a conformal lubricant layer thereover. The textured surface can include a plurality of raised first elements and a plurality of second elements thereon and the conformal lubricant layer over the plurality of raised first elements and covering the plurality of second elements. The plurality of raised first elements can have an average height of between 0.5 μm and 500 μm, and the plurality of second elements can have an average height of between 0.01 μm and 10 μm. Such substrates can be prepared by texturing a surface of a substrate with a plurality of raised first elements and a plurality of second elements thereon; optionally silanizing the textured surface and applying a lubricant layer over the plurality of raised first elements and between the plurality of second elements. |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/568639 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/00 (20130101) B05D 5/02 (20130101) B05D 5/08 (20130101) Original (OR) Class Cleaning in General; Prevention of Fouling in General B08B 17/065 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 59/022 (20130101) B29C 2059/023 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0092 (20130101) B29K 2995/0093 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434651 | Blankespoor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Kevin Blankespoor (Arlington, Massachusetts); Alexander Douglas Perkins (Arlington, Massachusetts) |
| ABSTRACT | A control system of a robotic device may receive sensor data indicating at least one deviation from a nominal operating parameter of the robotic device, where the robotic device includes articulable legs that include respective actuators, and where one or more strokes of the actuators cause the articulable legs to articulate. Based on the received sensor data, the control system may determine that the at least one deviation exceeds a pre-determined threshold. In response to determining that the at least one deviation exceeds the pre-determined threshold, the control system may provide instructions for centering the one or more strokes at approximately a mid-point of extension of the actuators, and reducing a stroke length of the one or more strokes of the actuators. |
| FILED | Saturday, January 13, 2018 |
| APPL NO | 15/870887 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/14 (20130101) B25J 9/1664 (20130101) B25J 9/1674 (20130101) Original (OR) Class B25J 9/1694 (20130101) B25J 17/00 (20130101) Motor Vehicles; Trailers B62D 57/032 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434888 | Hooper et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ralph David Hooper (Lemon Grove, California); Jeffery Towns Gilchrist (Cardiff, California); William A. Chambers (Jamul, California); Bradley Joseph Easterwood (Madison, Alabama); Brett Paul Lassus (Huntsville, Alabama); Paul Michael Collins (Madison, Alabama); Samuel Thomas Edwards (Decatur, Alabama); Terry Lance Silas (Panama City Beach, Florida); Marc Ludwig Roth (Owens Cross Roads, Alabama); Harry Lynn Barker (Madison, Alabama); Steven Dustin Bennett (Huntsville, Alabama) |
| ABSTRACT | A vehicle charging station comprising: a container comprising an upper portion having an air duct, and a lower portion comprising a support structure, a smoke detector, a fire-suppressant inlet, and a charging/communications junction, wherein the upper portion is configured to mate with the lower portion to form a weather-tight enclosure around a vehicle, and wherein removal of the upper portion allows for loading/unloading of the vehicle into/out of the lower portion; and a resource control unit (RCU) comprising a processor, an environmental control unit (ECU), a fire-suppressant control manifold, and a charger, wherein the ECU is operatively coupled to the air duct, the fire-suppressant control manifold is operatively coupled to the fire-suppressant inlet, the charger is electrically coupled to the charging/communications junction, and the processor is communicatively coupled to the smoke detector, the charging/communications junction, the ECU, the charger, and the fire-suppressant control manifold. |
| FILED | Wednesday, June 21, 2017 |
| APPL NO | 15/629568 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Fire-fighting A62C 3/10 (20130101) A62C 3/16 (20130101) A62C 37/04 (20130101) A62C 37/40 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 11/1824 (20130101) Original (OR) Class B60L 53/31 (20190201) B60L 2200/32 (20130101) B60L 2250/10 (20130101) Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 1/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435133 | Jansen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Jan T. Jansen (Florissant, Missouri); Ryan Stott (Cedar Hill, Missouri); William Vallellanes (St. Louis, Missouri); Jack Van Es (St. Charles, Missouri) |
| ABSTRACT | A stringer for having a runout with a raised area configured to reduces stress while improving drainage across the runout when utilized in a close structural component of a vehicle such as an aileron of an aircraft. In one or more configurations, the raised area of the runout of the stringer includes multiple tapered surfaces adjacent to one another oriented and configured as ramps to collectively guide water up, over and down the raised area of the stringer. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/044118 |
| ART UNIT | 3635 — Static Structures, Supports and Furniture |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 3/00 (20130101) Aeroplanes; Helicopters B64C 1/064 (20130101) Original (OR) Class B64C 3/182 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435218 | Little et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gregory D. Little (Ashland, Virginia); John P. Shebalin (Fredericksburg, Virginia); James S. Fetsko (Fredericksburg, Virginia); Joseph A. Silber (King George, Virginia); John E. Brough (Fredericksburg, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Gregory D. Little (Ashland, Virginia); John P. Shebalin (Fredericksburg, Virginia); James S. Fetsko (Fredericksburg, Virginia); Joseph A. Silber (King George, Virginia); John E. Brough (Fredericksburg, Virginia) |
| ABSTRACT | An ammunition tray is provided for containing a plurality of bullet cartridges within an ammunition box container having a stowage volume. The tray includes a substantially rectangular template having a horizontal surface bounded by first and second opposing longitudinal edges and opposing lateral edges joined at four corners. Each longitudinal edge includes a first tab bent substantially perpendicular to the surface to form a rib. Each lateral edge includes a second tab bent substantially perpendicular to the surface to form a wall. The surface includes a first row of internal cutouts that point towards the first longitudinal edge as a proximal orientation. The surface further includes a second row of internal cutouts that point towards the second longitudinal edge as a distal orientation. The template has longitudinal and lateral edges bent to form the respective ribs and walls fits within the stowage volume as a vertical stack of plural templates. Each first internal cutout in the first row can cradle a cartridge on the surface along the proximal orientation and can fit the cartridge from an adjacent second row. Each second internal cutout in the second row can cradle the cartridge on the surface along the distal orientation and can fit the cartridge from an adjacent first row. |
| FILED | Tuesday, May 02, 2017 |
| APPL NO | 15/584276 |
| ART UNIT | 3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 21/02 (20130101) B65D 21/0233 (20130101) B65D 71/70 (20130101) Original (OR) Class Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 9/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435457 | Watters et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Alexander Watters (North Andover, Massachusetts); Brendon Dusel (Cambridge, Massachusetts); Michael Super (Lexington, Massachusetts); Mark Cartwright (West Newton, Massachusetts); Donald E. Ingber (Boston, Massachusetts) |
| ABSTRACT | Described herein are engineered microbe-targeting molecules, microbe-targeting articles, kits comprising the same, and uses thereof. Such microbe-targeting molecules, microbe-targeting articles, or the kits comprising the same can not only bind or capture of a microbe or microbial matter thereof, but they also have improved capability (e.g., enhanced sensitivity or signal intensity) of detecting a microbe or microbial matter. Thus, the microbe-targeting molecules, microbe-targeting articles, and/or the kit described herein can be used in various applications, e.g., but not limited to assays for detection of a microbe or microbial matter, diagnostic and/or therapeutic agents for diagnosis and/or treatment of an infection caused by microbes in a subject or any environmental surface, and/or devices for removal of a microbe or microbial matter from a fluid. |
| FILED | Thursday, August 04, 2016 |
| APPL NO | 15/750788 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/00 (20130101) C07K 14/78 (20130101) Original (OR) Class C07K 14/4726 (20130101) C07K 19/00 (20130101) C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/569 (20130101) G01N 2333/78 (20130101) G01N 2400/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435461 | Lai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York); THE GOVERNING COUNCEL OF THE UNIVERSITY OF TORONTO (Toronto, Canada); U.S. ARMY MEDICAL RESEARCH AND MATERIAL COMMAND (Fort Detrick, Maryland) |
| ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York); The Governing Council of the University of Toronto (Toronto, Canada); The Government of the United States as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Jonathan R. Lai (Dobbs Ferry, New York); Jayne F. Koellhoffer (New York, New York); Julia Frei (Bronx, New York); Kartik Chandran (Brooklyn, New York); Sachdev Sidhu (Toronto, Canada); Gang Chen (Toronto, Canada); John M. Dye (Frederick, Maryland); Samantha Zak (Frederick, Maryland) |
| ABSTRACT | The present invention addresses a need for improved treatments for filovirus infections. This invention provides an isolated humanized anti-filovirus glycoprotein pre-fusion core antibody comprising a framework region having a sequence of 95% or greater identity to a human antibody framework region. Also provided is a method of treating and/or inhibiting a filovirus infection in a subject comprising administering to the subject an amount of any of the antibodies described herein, or an amount of an antigen-binding fragment thereof. Also provided is composition comprising any of the antibodies described herein, or or an amount of an antigen-binding fragment thereof. In an embodiment, the composition comprises a pharmaceutically acceptably carrier. |
| FILED | Thursday, August 06, 2015 |
| APPL NO | 15/327857 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435584 | Sampathkumaran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INNOSENSE LLC (Torrance, California) |
| ASSIGNEE(S) | INNOSENSE LLC (Torrance, California) |
| INVENTOR(S) | Uma Sampathkumaran (Torrance, California); Kevin H. Yu (Temple City, California); Corey M. Selman (West Hills, California) |
| ABSTRACT | The present invention relates to hydrophilic anti-fog coatings. In particular, the coatings use two types of nanoscale particles, colloidal silica and porous organosilicate micelles, in a polyurethane matrix. The invention is an anti-fog coating for optically clear substrates (polycarbonate, polyurethane, nylon, polyester and other clear plastics) without the need for a primer and glass substrates with an additional primer layer, comprising monosized colloidal silica nanoparticles and porous organosilicate micelles in a polyurethane matrix. The silica is preferably 1-5% by weight and the micelles are loaded at 0.1 to 10% volume percentage by volume. The polyurethane prepolymer is dissolved at 10-40% by weight in a mixture of tertiary amyl alcohol and diacetone alcohol to customize for dip, flow or spray coating processes. |
| FILED | Monday, December 11, 2017 |
| APPL NO | 15/838158 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/10 (20130101) C08G 18/10 (20130101) C08G 18/282 (20130101) C08G 77/26 (20130101) C08G 77/46 (20130101) C08G 2290/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/34 (20130101) C08K 3/34 (20130101) C08K 3/34 (20130101) C08K 3/36 (20130101) C08K 3/36 (20130101) C08K 7/26 (20130101) C08K 7/26 (20130101) C08K 2201/005 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 83/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 175/00 (20130101) C09D 175/00 (20130101) C09D 175/00 (20130101) C09D 175/04 (20130101) Original (OR) Class C09D 175/04 (20130101) Optical Elements, Systems, or Apparatus G02B 1/04 (20130101) G02B 1/04 (20130101) G02B 1/18 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435664 | Rao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore County (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| INVENTOR(S) | Govind Rao (Ellicott city, Maryland); Yordan Kostov (Columbia, Maryland); Leah Tolosa (Columbia, Maryland); Xudong Ge (Woodstock, Maryland); Douglas Frey (Ellicott City, Maryland) |
| ABSTRACT | A portable and mobile bioprocessing system and method for protein manufacturing that is compact, integrated and suited for on-demand production of any type of proteins and for delivery of the produced proteins to patients or for assay purposes. The portable system and method can also be used for efficient on-demand production of any type of protein with point-of-care delivery. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/966609 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/12 (20130101) C12M 47/10 (20130101) Original (OR) Class C12M 47/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435756 | Lieberman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Judy Lieberman (Brookline, Massachusetts); Fabio Petrocca (Boston, Massachusetts) |
| ABSTRACT | Described herein are novel malignancy associated gene signature biomarkers, and assays and methods thereof, to classify prognosis or malignant potential of a cancer and identify cancer-initiating cells. The malignancy associated gene signature biomarkers, assays and methods described herein provide, in part, new methodologies to screen for novel drugs for treating cancers and tumors, such as, for example, triple-negative breast tumors. Using the assays and methods described herein proteasome inhibitors, histone deacetylase inhibitors, and glycolysis inhibitors, were identified as being highly effective in altering gene expression signatures specifically in malignant or cancer-initiating cells. |
| FILED | Monday, May 22, 2017 |
| APPL NO | 15/601195 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) A61K 31/167 (20130101) A61K 31/713 (20130101) A61K 38/05 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) G01N 2500/10 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435785 | Curran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Seamus Curran (Pearland, Texas); Nigel Alley (Houston, Texas); Kang-Shyang Liao (Houston, Texas); Amrita Haldar (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON (Houston, Texas) |
| INVENTOR(S) | Seamus Curran (Pearland, Texas); Nigel Alley (Houston, Texas); Kang-Shyang Liao (Houston, Texas); Amrita Haldar (Houston, Texas) |
| ABSTRACT | A system and method for depositing a coating may comprise a coating chemical reactor, surface activation component, and a deposition component. A target surface may be prepared for deposition with the surface activation component. The coating chemical reactor may comprise a coating chemical dispenser and a coating chemical verifier that prepares the coating chemical for deposition. The coating chemical verifier may utilize an optical excitation source and at least one optical detector, wherein chemical substances are identified by unique signatures composed of binary code. The coating chemical may be received by the deposition component to depositing the coating chemical on the target surface. |
| FILED | Wednesday, June 11, 2014 |
| APPL NO | 14/301643 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/60 (20130101) B05D 3/064 (20130101) B05D 3/142 (20130101) B05D 5/08 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 17/30 (20130101) C03C 2218/31 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/12 (20130101) C23C 16/02 (20130101) Original (OR) Class C23C 16/44 (20130101) C23C 16/50 (20130101) C23C 16/52 (20130101) C23C 16/0227 (20130101) C23C 16/448 (20130101) C23C 16/452 (20130101) C23C 16/458 (20130101) C23C 16/482 (20130101) C23C 16/545 (20130101) C23C 16/4412 (20130101) C23C 16/45561 (20130101) Treating Textile Materials Using Liquids, Gases or Vapours D06B 1/08 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 10/04 (20130101) D06M 10/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435817 | Lieber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Charles M. Lieber (Lexington, Massachusetts); Robert Day (Somerville, Massachusetts); Max Nathan Mankin (Cambridge, Massachusetts); Ruixuan Gao (Cambridge, Massachusetts); Thomas J. Kempa (Somerville, Massachusetts) |
| ABSTRACT | The present invention generally relates to nanoscale wires, and to methods of producing nanoscale wires. In some aspects, the nanoscale wires are nanowires comprising a core which is continuous and a shell which may be continuous or discontinuous, and/or may have regions having different cross-sectional areas. In some embodiments, the shell regions are produced by passing the shell material (or a precursor thereof) over a core nanoscale wire under conditions in which Plateau-Raleigh crystal growth occurs, which can lead to non-homogenous deposition of the shell material on different regions of the core. The core and the shell each independently may comprise semiconductors, and/or non-semiconductor materials such as semiconductor oxides, metals, polymers, or the like. Other embodiments are generally directed to systems and methods of making or using such nanoscale wires, devices containing such nanoscale wires, or the like. |
| FILED | Wednesday, May 06, 2015 |
| APPL NO | 15/308951 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/22 (20130101) C23C 16/44 (20130101) C23C 18/08 (20130101) C23C 18/12 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/025 (20130101) C30B 25/18 (20130101) C30B 29/06 (20130101) C30B 29/08 (20130101) C30B 29/38 (20130101) C30B 29/60 (20130101) C30B 29/66 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0256 (20130101) H01L 21/02532 (20130101) H01L 21/02543 (20130101) H01L 21/02546 (20130101) H01L 21/02557 (20130101) H01L 21/02576 (20130101) H01L 21/02579 (20130101) H01L 21/02603 (20130101) H01L 21/02631 (20130101) H01L 29/16 (20130101) H01L 29/20 (20130101) H01L 29/22 (20130101) H01L 29/0673 (20130101) H01L 29/42392 (20130101) H01L 29/78696 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436110 | Holley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Adam Takashi Holley (Manchester, Connecticut); Peter A T Cocks (East Hartford, Connecticut); Christopher Britton Greene (East Hartford, Connecticut) |
| ABSTRACT | A rotating detonation engine includes an annulus that defines a volume in which a mixture of an oxidizer and a fuel detonate in a rotating fashion, the volume defining a downstream outlet through which detonation exhaust flows. The rotating detonation engine further includes a wave arrestor positioned upstream from a location of detonation and configured to reduce a magnitude of a pressure wave traveling upstream from the location of detonation. |
| FILED | Monday, March 27, 2017 |
| APPL NO | 15/470783 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 5/04 (20130101) F02C 5/12 (20130101) F02C 7/00 (20130101) Original (OR) Class Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 1/02 (20130101) F42B 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436115 | Duesler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Paul W. Duesler (Manchester, Connecticut); Frederick M. Schwarz (Glastonbury, Connecticut) |
| ABSTRACT | A gas turbine engine has a core engine with a compressor section and a turbine section. The compressor section includes a low pressure compressor and a high pressure compressor. A cooling air system taps compressed air and passes the compressed air through a heat exchanger. Cooling air passes over the heat exchanger to cool the compressed air, which is returned to the core engine to provide a cooling function. The heat exchanger is mounted through a flexible mount allowing movement between a static structure and the heat exchanger. |
| FILED | Monday, August 22, 2016 |
| APPL NO | 15/242973 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 6/12 (20130101) F02C 7/18 (20130101) Original (OR) Class F02C 7/20 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/30 (20130101) F05D 2260/96 (20130101) F05D 2260/213 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436117 | Lovett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Jeffery A. Lovett (Tolland, Connecticut); Darin A. Knaus (Lyme, New Hampshire); Scott D. Phillips (Enfield, New Hampshire); Daniel J. Micka (Enfield, New Hampshire); Patrick Magari (Plainfield, New Hampshire) |
| ABSTRACT | A fuel injection system for a gas turbine engine includes a vane in an airflow path within the gas turbine engine, the vane includes an air channel with an outlet in communication with the airflow path; and a fuel nozzle within the vane operable to inject fuel into the air channel to at least partially premix and prevaporize the fuel with a secondary airflow from within the vane in the air channel prior to entry into the airflow path through the outlet. A method of injecting fuel within a gas turbine engine includes at least partially premixing and prevaporizing fuel with a secondary airflow from within a vane in an air channel within the vane, the vane within an airflow path of the gas turbine engine. |
| FILED | Monday, November 18, 2013 |
| APPL NO | 14/083040 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/22 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/10 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/20 (20130101) F23R 3/30 (20130101) F23R 3/286 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/494 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436209 | Pinera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida Turbine Technologies, Inc. (Jupiter, Florida) |
| ASSIGNEE(S) | FLORIDA TURBINE TECHNOLOGIES, INC. (Jupiter, Florida) |
| INVENTOR(S) | Alex Pinera (Jupiter, Florida); Stephen M Brooks (Jupiter, Florida) |
| ABSTRACT | A turbomachine such as a turbocharger with an air journal bearing and an air thrust bearing arrangement with a fixed air journal bearing connected in series with a floating air journal bearing connected by a hollow spring to supply compressed air from the fixed air journal bearing to the floating air journal bearing, and a forward air thrust bearing and an aft air thrust bearing connected in parallel to a source of compressed air. An air vent cavity is formed between the forward bearing and the aft bearing in which compressed air from all four bearings can be collected and discharged from a housing. Some of the compressed air from the forward thrust bearing is discharged with a compressor outlet, and some of the compressed air from the aft thrust bearing is discharged into a turbine inlet. |
| FILED | Friday, February 10, 2017 |
| APPL NO | 15/429212 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/16 (20130101) Non-positive-displacement Pumps F04D 29/051 (20130101) Original (OR) Class F04D 29/056 (20130101) F04D 29/668 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/40 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 32/0622 (20130101) F16C 32/0677 (20130101) F16C 32/0696 (20130101) F16C 2360/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436241 | Hooper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Government (San Diego, California) |
| ASSIGNEE(S) | United States Government as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ralph David Hooper (Lemon Grove, California); William A. Chambers (Jamul, California); James Benjamin Penney (Carlsbad, California) |
| ABSTRACT | A snap-hook, including a hook and a dual-direction latch pivotally attached to the hook by a latch pin. The dual-direction latch blocks an opening to the hook's throat when held in a neutral position by a latch spring having a first spring force and a lever-return spring having a second spring force. The dual-direction latch is configured to move into the throat by overcoming the first spring force and to move out of the throat by overcoming the second spring force. The dual-direction latch comprises a spring guard attached to the dual-direction latch so as to shield the lever-return spring from coming into contact with one or both of an object disposed within a throat of the hook and an inner edge of the hook throat. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 15/906678 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 45/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436558 | Gilliam |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jason C. Gilliam (Huntsville, Alabama) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (, None) |
| INVENTOR(S) | Jason C. Gilliam (Huntsville, Alabama) |
| ABSTRACT | A preformed warhead is provided with a casing having a front section and a rear section. A plurality of target piercing fragments is arranged at the front section. The density of a given fragment diminishes the further the given fragment is from a centerline of the warhead. An initiating point located on the centerline is positioned at the rear section of the warhead. An explosive charge is positioned between the initiating point and the target piercing fragments. Upon detonation of the warhead, the explosive wave propagates in a radial fashion such that the fragments receiving the impact of the explosive force soonest and most directly are those fragments closest to the centerline. Thus, a substantially planar velocity profile of all the fragments is achieved. |
| FILED | Thursday, December 18, 2008 |
| APPL NO | 12/322954 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436616 | Carney |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Kenneth Carney (Rancho Cucamonga, California) |
| ABSTRACT | A system has at least one sensor and a control for analyzing a signal from the sensor. The sensor is operable to send a signal indicative of a presence of a particular occurrence to the control. The sensor also sends a background signal even without the presence of the particular occurrence. The control evaluates the background signal to identify a need for calibration. A method is also disclosed. |
| FILED | Monday, August 08, 2016 |
| APPL NO | 15/230886 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 18/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436650 | Maurer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Peter Christian Maurer (Boston, Massachusetts); Hyun Ji Noh (Boston, Massachusetts); Georg Kucsko (Cambridge, Massachusetts); Mikhail D. Lukin (Cambridge, Massachusetts); Hongkun Park (Lexington, Massachusetts); Minako Kubo (Cambridge, Massachusetts) |
| ABSTRACT | An approach to nanoscale thermometry that utilizes coherent manipulation of the electronic spin associated with nitrogen-vacancy (NV) color centers in diamond is disclosed. The methods and apparatus allow for detection of temperature variations down to milli-Kelvin resolution, at nanometer length scales. This biologically compatible approach to thermometry offers superior temperature sensitivity and reproducibility with a reduced measurement time. The disclosed apparatus can be used to study heat-generating intracellular processes. |
| FILED | Tuesday, April 01, 2014 |
| APPL NO | 14/781382 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/32 (20130101) Original (OR) Class G01K 11/20 (20130101) G01K 13/00 (20130101) G01K 2211/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436724 | Grimshaw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Matthew T. Grimshaw (Seattle, Washington); Talion Edwards (Wentzville, Missouri); Gary E. Georgeson (Tacoma, Washington); Daniel J. Wright (Mercer Island, Washington); James E. Engel (Newport Beach, California); Morteza Safai (Newcastle, Washington); Yuan-Jye Wu (Issaquah, Washington); Taisia Tsukruk Lou (St. Louis, Missouri); Rodney S. Wright (Huntington Beach, California) |
| ABSTRACT | A system for quantifying x-ray backscatter system performance may include a support; a plurality of rods mounted on the support; the rods of the plurality of rods arranged parallel to each other, having generally curved outer surfaces, and being arranged in groups of varying widths, each group of the groups having at least two of the rods of a same width; and a user interface configured to be connected to receive a backscatter signal from an x-ray backscatter detector associated with an x-ray tube, apply a transfer function to generate a transfer curve representing x-ray backscatter for each rod of the plurality of rods from x-rays transmitted by the x-ray tube. |
| FILED | Thursday, June 16, 2016 |
| APPL NO | 15/184644 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/203 (20130101) Original (OR) Class G01N 2223/303 (20130101) G01N 2223/408 (20130101) G01N 2223/631 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/0025 (20130101) X-ray Technique H05G 1/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436744 | Friedman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Adam L. Friedman (Silver Spring, Maryland); F. Keith Perkins (Alexandria, Virginia); James C. Culbertson (Alexandria, Virginia); Aubrey T. Hanbicki (Washington, District of Columbia); Paul M. Campbell (Alexandria, Virginia) |
| ABSTRACT | A method of making a low dimensional material chemical vapor sensor comprising providing a monolayer of a transition metal dichalcogenide, applying the monolayer to a substrate, applying a PMMA film, defining trenches, and placing the device in a n-butyl lithium (nbl) bath. A low dimensional material chemical vapor sensor comprising a monolayer of a transition metal dichalcogenide, the monolayer applied to a substrate, a region or regions of the transition metal dichalcogenide that have been treated with n-butyl lithium, the region or regions of the transition metal dichalcogenide that have been treated with n-butyl lithium have transitioned from a semiconducting to metallic phase, metal contacts on the region or regions of the transition metal dichalcogenide that have been treated with the n-butyl lithium. |
| FILED | Tuesday, April 04, 2017 |
| APPL NO | 15/479014 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4141 (20130101) Original (OR) Class G01N 33/0057 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 1/20 (20130101) G03F 7/405 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) H01L 29/66969 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436767 | Bellotti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NLA Diagnostics LLC (Charlotte, North Carolina) |
| ASSIGNEE(S) | NLA Diagnostics LLC (Charlotte, North Carolina) |
| INVENTOR(S) | Aldo Bellotti (Charlotte, North Carolina); Ralph N. Strayhorn, IV (Charlotte, North Carolina) |
| ABSTRACT | A device and method for determining characteristics of a concrete sample includes the use of multiple transducers. The transducers may couple to the concrete surface so that they can impart or receive mechanical waves from the sample. An area within a plane in the concrete sample is bounded by a collective extent of mechanical waves that pass through the plane and has a dimension at least as long as a distance between reinforcing bars in the concrete. |
| FILED | Monday, April 09, 2018 |
| APPL NO | 15/948963 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/348 (20130101) G01N 33/383 (20130101) Original (OR) Class G01N 2291/011 (20130101) G01N 2291/0232 (20130101) G01N 2291/0422 (20130101) G01N 2291/02827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436784 | Blakely et al. |
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| FUNDED BY |
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| APPLICANT(S) | Meso Scale Technologies, LLC (Rockville, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | Meso Scale Technologies, LLC (Rockville, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | William F Blakely (Silver Spring, Maryland); Eli N. Glezer (Del Mar, California); John Kenten (Boyds, Maryland); Sudeep Kumar (Gaithersburg, Maryland); Anu Mathew (North Potomac, Maryland); Natalia I. Ossetrova (Silver Spring, Maryland); George Sigal (Rockville, Maryland) |
| ABSTRACT | The present invention relates to methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. The invention also relates to algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure. |
| FILED | Tuesday, September 15, 2015 |
| APPL NO | 14/854514 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 33/6893 (20130101) G01N 33/56972 (20130101) Original (OR) Class G01N 2333/70535 (20130101) G01N 2333/70578 (20130101) G01N 2800/40 (20130101) G01N 2800/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436855 | Sternberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Oren Sternberg (San Diego, California); John D. Rockway (San Diego, California); Jeffery C. Allen (San Diego, California) |
| ABSTRACT | An optically detected power quality disturbance caused by a remote load is classified as belonging to a class of known classes of power quality disturbances. Features associated with different power quality disturbances that belong to a plurality of different known classes of power quality disturbances are learned. Cross-covariance is applied to the optically detected power quality disturbance and the different power quality disturbances that belong to the different known classes of power quality disturbances to recognize features of the optically detected power quality disturbance that at least partially match the learned features. The class of power quality disturbances among the plurality of classes of different known power quality disturbances to which the optically detected power quality disturbance belongs is determined based on the recognized features. |
| FILED | Thursday, August 10, 2017 |
| APPL NO | 15/674193 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/40 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/627 (20130101) G06K 9/628 (20130101) G06K 9/00718 (20130101) G06K 9/4661 (20130101) G06K 9/6202 (20130101) G06K 2009/00738 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436897 | Ranney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by the Secretary of the Army (Army Research Laboratory) (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth Irving Ranney (Rockville, Maryland); David Chun Wong (Clarksville, Maryland); Tuan That Ton (Springfield, Virginia) |
| ABSTRACT | A system for determining the location of a man-made object based upon symmetry of the object comprising a receiver configured to receive radar signals comprising cross-polarized and co-polarized responses; at least one processor configured to combine the horizontal-horizontal polarimetric responses and vertical-vertical polarimetric responses to form co-polarimetric images and operate on one or both of the vertical-horizontal polarimetric responses and horizontal-vertical polarimetric responses to form cross-polarized images; the at least one processor configured to process the co-polarized and cross-polarized images to locate areas of interest containing a maximum in the co-pol image and a null state in the co-pol image indicating the potential detection of a man-made object; the at least one processor being configured to filter data using buffer regions and/or skipping of pixels in the vicinity of an area of interest. A method for detection of man-made objects is also disclosed. |
| FILED | Friday, February 03, 2017 |
| APPL NO | 15/423723 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/024 (20130101) G01S 7/025 (20130101) G01S 7/292 (20130101) G01S 7/412 (20130101) G01S 13/86 (20130101) G01S 13/90 (20130101) Original (OR) Class G01S 13/867 (20130101) G01S 13/885 (20130101) G01S 13/887 (20130101) G01S 13/9076 (20190501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436909 | Ouyang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia); Cuiling Gong (Dallas, Texas) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Bing Ouyang (Vero Beach, Florida); Weilin Hou (Slidell, Louisiana); Fraser Dalgleish (Vero Beach, Florida); Cuiling Gong (Dallas, Texas); Frank Caimi (Vero Beach, Florida); Anni Dalgleish (Vero Beach, Florida) |
| ABSTRACT | Embodiments relate to compressive line sensing imaging. Initially, a codebook is configured with a pattern sequence for a series of illumination patterns. Each light element in an individually addressable laser diode array (IALDA) is independently controlled to project the series of illumination patterns onto a target. Next, measurements of the target are acquired based on the series of illumination patterns. The codebook is then used to decode the measurements to create an image of the target. |
| FILED | Monday, October 31, 2016 |
| APPL NO | 15/339099 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) G01S 7/4808 (20130101) G01S 7/4815 (20130101) G01S 17/89 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10437001 | Gifford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Th United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Michael M Gifford (Marion, Massachusetts); Frank S LiVolski (Wakefield, Rhode Island); Zachary A Whittaker (Warwick, Rhode Island) |
| ABSTRACT | A drogue and mandrel are provided for securing a fiber optic link in which the mandrel has halves with winding knobs on the ends of the mandrel. One half includes pegs for positioning the link with a fiber optic splice between the pegs. The halves attach at the pegs such that the knobs can wind to secure the link on a lined surface of one of the halves. The halves have grooves to protect the link from breaking during winding. A pair of guide tubes and the mandrel including the fiber optic link are positioned in the drogue with the tubes tangent to the mandrel to ensure that there is no obstruction. A second half of the mandrel features arresting teeth that interfaces with recesses threaded winding knobs to prevent unwinding. A circumferential fin assists with inducing drag of the drogue. |
| FILED | Thursday, September 20, 2018 |
| APPL NO | 16/136587 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4457 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10437132 | Koehler |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Elka E. Koehler (Tucson, Arizona) |
| ABSTRACT | Examples provide a compact, dynamic non-uniformity correction mechanism and counter-countermeasure mechanism. In one example an optical imaging system includes an imaging sensor configured to receive optical radiation and to produce an image of a viewed scene from the optical radiation, an optical train including at least one optical component configured to receive the optical radiation from the viewed scene and to focus the optical radiation to the imaging sensor, and an acousto-optic modulator positioned in the optical train and having an ON state and an OFF state, the acousto-optic modulator being configured in the OFF state to pass the optical radiation, and the acousto-optic modulator being configured in the ON state to diffract the optical radiation and blur the image produced by the imaging sensor from the diffracted optical radiation. |
| FILED | Tuesday, March 20, 2018 |
| APPL NO | 15/926229 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4795 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/11 (20130101) G02F 1/332 (20130101) Original (OR) Class G02F 1/2255 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10437664 | Sud |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Seema Sud (Reston, Virginia) |
| ABSTRACT | A signal-of-interest (SOI) may be separated from interference and/or noise using repeated reduced rank minimum mean-square error Fractional Fourier Transform (MMSE-FrFT) filtering and a low rank adaptive multistage Wiener filter (MWF). A number of stages in the MWF, L, may be chosen such that at the Lth stage, the MSE between the SIM estimate and the true SW is less than or equal to an error threshold ∈ (e.g., ∈=0.001). By combining these filtering techniques, significant improvement in reducing the mean-square error (MSE) may be realized over single stage MMSE-FrFT, repeated MMSE-FrFT, and MMSE-FFT algorithms—indeed, by an order of magnitude or more. |
| FILED | Friday, September 08, 2017 |
| APPL NO | 15/698697 |
| ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 7/48 (20130101) G06F 11/0751 (20130101) G06F 11/0793 (20130101) Original (OR) Class Impedance Networks, e.g Resonant Circuits; Resonators H03H 17/0213 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10437854 | Gabrys |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ryan C. Gabrys (San Diego, California) |
| ABSTRACT | A method synchronizes related data across networked host devices. At each of a first and a second host device, string vectors are created for each document stored within the host device. The respective set of string vectors are encoded using a two-dimensional hash, where a first dimension of the two-dimensional hash stores string vector differences between all elements that reside in a symmetric difference and a second dimension of the two-dimensional hash stores one string vector from the symmetric difference. The respective encoded set of string vectors is transmitted to the other host device, which then decodes the respective encoded set of string vectors received to arrive at the symmetric difference. The host device determines which string vectors it is missing and requests from the other host device the missing documents pertaining to the missing string vectors. The missing documents are received by the requesting host device. |
| FILED | Tuesday, May 09, 2017 |
| APPL NO | 15/590200 |
| ART UNIT | 2169 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/273 (20190101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 2220/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10437943 | Chrisp |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael Chrisp (Burlington, Massachusetts) |
| ABSTRACT | A method of and program for optimizing NURBS optical surfaces for an imaging system. Preferably, the number and location of field point sources to be used in ray tracing of a NURBS modeled imaging system surfaces are determined by automatically iteratively increasing the number of field point sources during ray tracing until the spot size from adjacent field points sources on the image plane of the imaging system varies by less than a predetermined value. The number of rays for each field point source to be used in ray tracing of the NURBS modeled imaging system surfaces is preferably determined by automatically iteratively increasing the number of rays for each field point source during ray tracing until a predetermined number of rays intersect each NURBS rectangular grid sub-area. In ray tracing the modeled NURBS surfaces, the determined number and location of field point sources and the determined number of rays from each field point source are used and the grid control points of each NURBS surface are preferably iteratively adjusted, keeping symmetry or allowing freeform shapes, by means of an optimization algorithm based on ray tracing until spot sizes on the image plane meet a set requirement and/or until improvement in spot size is below a predetermined value. |
| FILED | Wednesday, February 24, 2016 |
| APPL NO | 15/051787 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 7/028 (20130101) Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class G06F 17/5086 (20130101) Image Data Processing or Generation, in General G06T 17/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10437993 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
| INVENTOR(S) | Ang Chen (Philadelphia, Pennsylvania); Hanjun Xiao (Philadelphia, Pennsylvania); William Bradley Moore (Washington, District of Columbia); Andreas Haeberlen (Philadelphia, Pennsylvania); Linh Thi Xuan Phan (Philadelphia, Pennsylvania); Micah Sherr (Silver Spring, Maryland); Wenchao Zhou (Vienna, Virginia) |
| ABSTRACT | A mechanism called time-deterministic replay (TOR) that can reproduce the execution of a program, including its precise timing. Without TOR, reproducing the timing of an execution is difficult because there are many sources of timing variability. TOR uses a combination of techniques to either mitigate or eliminate most of these sources of variability. Using a prototype implementation of TOR in a Java Virtual Machine, we show it is possible to reproduce the timing to within 1.85% of the original execution. A study of one of the applications of TOR is described: the detection of a covert timing channel. Timing channels can be used to exfiltrate information from a compromised machine by subtly varying timing of the machine's outputs, TOR can detect this variation. Unlike prior solutions, which generally look for a specific type of timing channel, our approach can detect a wide variety of channels with high accuracy. |
| FILED | Monday, October 05, 2015 |
| APPL NO | 15/514820 |
| ART UNIT | 2492 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) G06F 21/12 (20130101) G06F 21/53 (20130101) G06F 21/75 (20130101) G06F 21/556 (20130101) Original (OR) Class G06F 2009/45587 (20130101) G06F 2221/033 (20130101) G06F 2221/2151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438156 | Swanson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aptima, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | APTIMA, INC. (Woburn, Massachusetts) |
| INVENTOR(S) | Leah Swanson (Beavercreek, Ohio); Kristy Reynolds (Billings, Montana); Michael Garrity (Londonderry, New Hampshire); Tiffany Poeppelman (Centerville, Ohio); Michael Keeney (Sterling, Virginia); Alan Carlin (Arlington, Massachusetts); Danielle Dumond (Haverhill, Massachusetts); Yale Marc (Winchester, Massachusetts) |
| ABSTRACT | Systems and methods to provide a training solution for a trainee are disclosed. In some embodiments the method comprises receiving a training requirement comprising a training outcome and a training configuration wherein the training configuration defines a trainee state, determining a training environment based on a relevancy function of the training environment to the training outcome, determining a training content based on a relationship function of the training content to the trainee state and determining a training solution comprising the training environment and the training content. In some embodiments, the relationship function comprises a POMDP model and the relevancy function comprises a best fit curve. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/207684 |
| ART UNIT | 3624 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06398 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438305 | Song et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Siemens Corporation (Iselin, New Jersey) |
| ASSIGNEE(S) | SIEMENS CORPORATION (Iselin, New Jersey) |
| INVENTOR(S) | Zhen Song (Plainsboro, New Jersey); Xianjun S. Zheng (Plainsboro, New Jersey); Sanjeev Srivastava (Princeton, New Jersey) |
| ABSTRACT | A computer-implemented method of splitting whole building energy consumption includes collecting sensor data from a plurality Variable Air Volume (VAV) boxes in a building, an electric meter in the building, and a gas meter in the building. The total heating energy consumption is split across a plurality of zones within the building using the sensor data, thereby yielding heating energy consumption for each zone. The total cooling energy consumption is split across the plurality of zones using the sensor data, thereby yielding cooling energy consumption for each zone and the total ventilation energy consumption is split across the plurality of zones using the sensor data, thereby yielding ventilation energy consumption for each zone. Zone energy consumption by aggregating the heating energy consumption for the zone, the cooling energy consumption for the zone, and the ventilation energy consumption for the zone. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 15/468154 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/0001 (20130101) F24F 11/46 (20180101) F24F 11/52 (20180101) F24F 11/63 (20180101) F24F 2140/20 (20180101) F24F 2140/60 (20180101) Measuring Electric Variables; Measuring Magnetic Variables G01R 21/00 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) G05B 2219/2639 (20130101) G05B 2219/2642 (20130101) Electric Digital Data Processing G06F 1/3203 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438366 | Seetharaman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES AS REPRESETNED BY SECRETARY OF THE AIR FORCE (Rome, New York) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Gunasekaran Seetharaman (Alexandria, Virginia); Kannappan Palaniappan (Columbia, Missouri); Hadi Ali Akbarpour (Columbia, Missouri) |
| ABSTRACT | The present invention provides a method for fast, robust and efficient BA pipeline (SfM) for wide area motion imagery (WAMI). The invention can, without applying direct outliers filtering (e.g. RANSAC) or re-estimation of the camera parameters (e.g. essential matrix estimation) efficiently refine noisy camera parameters in very short amounts of time. The method is highly robust owing to its adaptivity with the persistency factor of each track. The present invention highly suitable for sequential aerial imagery, particularly for WAMI, where camera parameters are available from onboard sensors. |
| FILED | Thursday, February 01, 2018 |
| APPL NO | 15/885874 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00208 (20130101) Image Data Processing or Generation, in General G06T 7/73 (20170101) G06T 7/579 (20170101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/30244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438413 | Bilinski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mark Bilinski (Vista, California); Larry Clay Greunke (Lakeside, California) |
| ABSTRACT | A method for using a virtual reality (VR) headset to view a two-dimensional (2D) technical drawing of a physical object of a real-world, real-world environment in three dimensions (3D), the method comprising: using LiDAR to produce a 3D point cloud of the real-world environment; scaling and aligning the 2D technical drawing to match the size and orientation of the physical object as depicted in the 3D point cloud; overlaying the 2D technical drawing (including all labels and dimensions) over the physical object as depicted in the 3D point cloud; and visually comparing the 3D point cloud representation of the physical object to the 2D technical drawing by simultaneously displaying the 3D point cloud of the real-world environment and the overlaid 2D technical drawing to a user with the VR headset. |
| FILED | Tuesday, November 07, 2017 |
| APPL NO | 15/806125 |
| ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/00 (20130101) Optical Elements, Systems, or Apparatus G02B 27/0172 (20130101) Image Data Processing or Generation, in General G06T 11/60 (20130101) G06T 19/006 (20130101) Original (OR) Class G06T 2210/04 (20130101) Pictorial Communication, e.g Television H04N 13/344 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438700 | Ortiz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Edward A. Ortiz (Charlottesville, Virginia); Stephen D. Patek (Charlottesville, Virginia); Marc D. Breton (Charlottesville, Virginia); Leon S. Farhi (Charlottesville, Virginia); Boris P. Kovatchev (Charlottesville, Virginia) |
| ABSTRACT | Time-varying hyperglycemic stresses are derived from actual ICU patients and applied to non-critically ill virtual patients, using any model of normal glucose-insulin physiology that fulfills certain requirements, in order to model and simulate stress hyperglycemia. Other aspects provide: 1) a methodology to perform sensitivity analyses of the parameters of ICU insulin infusion therapy protocols and to improve the protocols; and 2) a training system for clinicians about the course and management of stress hyperglycemia in the ICU or other facility. |
| FILED | Monday, August 05, 2013 |
| APPL NO | 14/419375 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/54 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438753 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kang Xu (North Potomac, Maryland); Arthur Von Cresce (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Kang Xu (North Potomac, Maryland); Arthur Von Cresce (Rockville, Maryland) |
| ABSTRACT | This invention described the preparation of a series of compounds that can be used as co-solvents, solutes or additives in non-aqueous electrolytes and their test results in various electrochemical devices. The inclusion of these novel compounds in electrolyte systems can enable rechargeable chemistries at high voltages that are otherwise impossible with state-of-the-art electrolyte technologies. These compounds are so chosen because of their beneficial effect on the interphasial chemistries formed at high potentials, such as 5.0 V class cathodes for new Li ion chemistries. The potential application of these compounds goes beyond Li ion battery technology and covers any electrochemical device that employs non-aqueous electrolytes for the benefit of high energy density resultant from high operating voltages. |
| FILED | Tuesday, November 23, 2010 |
| APPL NO | 12/952354 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/58 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1653 (20130101) H01M 10/052 (20130101) H01M 10/0567 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438773 | Kobernik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PHOENIX LLC (Monona, Wisconsin) |
| ASSIGNEE(S) | PHOENIX LLC (Monona, Wisconsin) |
| INVENTOR(S) | Arne Kobernik (Monona, Wisconsin); Carl Sherven (Monona, Wisconsin); Casey Lamers (Monona, Wisconsin); Chris Seyfert (Monona, Wisconsin); Evan Sengbusch (Monona, Wisconsin); Gabriel Becerra (Monona, Wisconsin); Jin Lee (Monona, Wisconsin); Logan Campbell (Monona, Wisconsin); Mark Thomas (Monona, Wisconsin); Michael Taylor (Monona, Wisconsin); Preston Barrows (Monona, Wisconsin); Ross Radel (Monona, Wisconsin); Tye Gribb (Monona, Wisconsin) |
| ABSTRACT | Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196710 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/32082 (20130101) Original (OR) Class Spark Gaps; Overvoltage Arresters Using Spark Gaps; Sparking Plugs; Corona Devices; Generating Ions to be Introduced into Non-enclosed Gases H01T 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439091 | King et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Richard R. King (Thousand Oaks, California); Christopher M. Fetzer (Valencia, California); Daniel C. Law (Arcadia, California); Xing-Quan Liu (Arcadia, California); William D. Hong (Los Angeles, California); Kenneth M. Edmondson (Burbank, California); Dimitri D. Krut (Encino, California); Joseph C. Boisvert (Thousand Oaks, California); Nasser H. Karam (La Canada, California) |
| ABSTRACT | In one aspect, optoelectronic devices are described herein. In some implementations, an optoelectronic device comprises a photovoltaic cell. The photovoltaic cell comprises a space-charge region, a quasi-neutral region, and a low bandgap absorber region (LBAR) layer or an improved transport (IT) layer at least partially positioned in the quasi-neutral region of the cell. |
| FILED | Wednesday, November 16, 2016 |
| APPL NO | 15/353557 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0352 (20130101) H01L 31/0687 (20130101) H01L 31/0725 (20130101) Original (OR) Class H01L 31/0735 (20130101) H01L 31/035209 (20130101) H01L 31/035218 (20130101) H01L 31/035227 (20130101) H01L 31/035272 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439291 | Grossman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Kenneth R. Grossman (Olney, Maryland); Joseph A. Miragliotta (Ellicott City, Maryland); Adam J. Maisano (Sykesville, Maryland); Douglas B. Trigg (Elkton, Maryland) |
| ABSTRACT | A radio frequency surface wave attenuator structure is provided. The structure may be configured to be operably coupled with a plurality of other radio frequency surface wave attenuator structures to form a metamaterial. The radio frequency surface wave attenuator structure may include a patch disposed in a first plane and defining a patch area and a backplane disposed in a second plane and extending along the second plane to be shared with the other surface wave attenuator structures. The structure may further include a via spring having a number of turns and being comprised of a conductive material. The via spring may electrically couple the patch to the backplane. The structure may further include a dielectric disposed between the patch and the backplane. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/884426 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/52 (20130101) H01Q 15/008 (20130101) Original (OR) Class H01Q 17/007 (20130101) H01Q 17/008 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/48 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439292 | Grossman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Kenneth R. Grossman (Olney, Maryland); Joseph A. Miragliotta (Ellicott City, Maryland); Adam J. Maisano (Sykesville, Maryland); Douglas B. Trigg (Laurel, Maryland); Steven M. Storck (Timonium, Maryland) |
| ABSTRACT | Electromagnetic shielding systems, apparatuses, and method are provided. One apparatus is an example free-space absorber metamaterial that includes a first array of patches disposed at a first plane, a conductive backplane disposed at a structural surface plane, and a first dielectric spacer disposed between the first array of patches and the conductive backplane. A first bandwidth of absorption for the free-space absorber metamaterial may be based on the area of a patch in the first array of patches, the first electrical resistance of a patch in the first array of patches, and the first gap distance taken between the first array of patches and the conductive backplane. |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/026685 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/52 (20130101) H01Q 15/0086 (20130101) Original (OR) Class H01Q 17/007 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439323 | Higgins |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Shawn Orion Higgins (Ridgecrest, California) |
| ABSTRACT | A high voltage RF connector for coaxial-to-stripline transition is capable of withstanding high voltages and providing impedance matching at RF frequencies. The high voltage RF connector comprises a bulkhead connector adapted to couple a coaxial cable connector. As the bulkhead connector matingly engages the coaxial cable connector, a first air gap forms therebetween, having an impedance determined, at least in part, by a first air gap distance between a first bulkhead connector dielectric insert and a coaxial cable connector dielectric insert. A second air gap also forms between first and second bulkhead connector dielectric inserts, both located within the bulkhead connector. The second air gap has approximately the same air gap distance and shape as the first air gap. |
| FILED | Tuesday, September 04, 2018 |
| APPL NO | 16/121016 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/502 (20130101) H01R 13/622 (20130101) Original (OR) Class H01R 24/40 (20130101) H01R 2103/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439402 | Boehmer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Tyler J. Boehmer (Columbia, Maryland); Deanna K. Temkin (Silver Spring, Maryland) |
| ABSTRACT | An adaptive power system for powering a dynamically changing load may include an energy storage device, a bi-directional current source, and compensation circuitry. The bi-directional current source may be electrically connected between the energy storage device and a power distribution bus of a power distribution system. Further, the bi-directional current source is configured to receive a compensation value and, based on the compensation value, maintain a constant power level on the power distribution bus by delivering current to the power distribution bus from the energy storage device or absorbing current from the power distribution bus for storage in the energy storage device. The compensation circuitry may be configured to generate the compensation value. An expected average current value for the dynamically changing load and a power distribution bus current value may be used to generate the compensation value for maintaining the constant power level on the power distribution bus. |
| FILED | Wednesday, December 13, 2017 |
| APPL NO | 15/840085 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 5/00 (20130101) Original (OR) Class H02J 7/345 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/44 (20130101) H02M 3/158 (20130101) H02M 3/33584 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439696 | Baek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Andrew S. Baek (Irvine, California); Thompson Truong (Fullerton, California); Othon Equihua (Downey, California); Kevin Kanemori (Torrance, California) |
| ABSTRACT | A method and apparatus for generating a covariance matrix during adaptive beamforming of a multi-beam antenna. The method uses an upper right triangle of the covariance and time sharing of complex conjugate multipliers to efficiently compute the covariance matrix. In addition, a variable number of beams may be selected in the covariance matrix according to an operating environment of the multi-beam antenna. |
| FILED | Tuesday, September 11, 2018 |
| APPL NO | 16/127597 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 7/0617 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439737 | Hughes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Rome, New York) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | David H. Hughes (Blossvale, New York); Reinhard K. Erdmann (Richfield Springs, New York) |
| ABSTRACT | A hyper-entanglement photon server (i.e., hub) employs non-degenerate frequencies input as entangled photon pairs into a beam splitter. The beam splitter splits probability amplitudes into two sets of bunched superposition states plus two sets of anti-bunched superposition states. The amplitudes pass through identical Lyot filters and then either enter a polarization beam splitter, where the bunched and anti-bunched states switch identities, or merely advance unchanged to awaiting users at two distinct and spatially-displaced positions (i.e., spokes). The Lyot filters change the output amplitudes from rotationally invariant superpositions of generalized Bell States to rotationally non-invariant superpositions of generalized Bell states. All hubs and spokes pre-share operating key material (a security method called KCQ) that may be continually updated by shared stream ciphers seeded by fresh key material engendered by hub-to-spoke quantum communication. |
| FILED | Tuesday, February 13, 2018 |
| APPL NO | 15/895545 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/02 (20130101) Optical Elements, Systems, or Apparatus G02B 27/141 (20130101) G02B 27/283 (20130101) G02B 27/288 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Transmission H04B 10/70 (20130101) H04B 10/85 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0618 (20130101) H04L 9/0855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439755 | Krunz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Marwan M. Krunz (Tucson, Arizona); Berk Akgun (Tucson, Arizona); Peyman Siyari (Tucson, Arizona); Hanif Rahbari (Tucson, Arizona); Rashad Mohamed Eletreby (Tucson, Arizona); Onur Ozan Koyluoglu (Tucson, Arizona) |
| ABSTRACT | Systems and methods of friendly jamming for securing wireless communications at the physical layer are presented. Under the assumption of exact knowledge of the eavesdropping channel, a resource-efficient distributed approach is used to improve the secrecy sum-rate of a multi-link network with one or more eavesdroppers while satisfying an information-rate constraint for all links. A method based on mixed strategic games can offer robust solutions to the distributed secrecy sum-rate maximization. In addition, a block fading broadcast channel with a multi-antenna transmitter, sending two or more independent confidential data streams to two or more respective users in the presence of a passive eavesdropper is considered. Lastly, a per-link strategy is considered and an optimization problem is formulated, which aims at jointly optimizing the power allocation and placement of the friendly jamming devices for a given link under secrecy constraints. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/012620 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 1/12 (20130101) Secret Communication; Jamming of Communication H04K 3/60 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439799 | Diallo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mamadou H. Diallo (San Diego, California); Roger Alexander Hallman (San Diego, California); Michael Anthony August (San Diego, California); Megan Elane Monteverde Kline (San Diego, California); Henry Gwok Wing Au (Honolulu, Hawaii) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mamadou H. Diallo (San Diego, California); Roger Alexander Hallman (San Diego, California); Michael Anthony August (San Diego, California); Megan Elane Monteverde Kline (San Diego, California); Henry Gwok Wing Au (Honolulu, Hawaii) |
| ABSTRACT | Indirect fire protocol according to several embodiments of the present invention can include the initial step establishing a grid and locating a forward observer (FO) and a firing unit (FU) in the grid. The FO can estimate the bearing and range to a High Value Target (HVT) within the grid, and can homomorphically encrypting said HVT estimated position data. FO can then transmit the encrypted HVT estimated position data over cloud network architecture to a Fire Direction Center (FDC), using the FDC's Keypublic. The FDC can outsource the calculation of an absolute position of said HVT in said grid to non-secure internet cloud architecture, but with encrypted HVT estimation data and the FO position data in the grid (which the FDC knows). Once calculated, the HVT encrypted absolute position data can be decrypted, and then transmitted from FDC to a FU, using the FU's Keypublic. |
| FILED | Thursday, August 17, 2017 |
| APPL NO | 15/679932 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/602 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) Original (OR) Class H04L 9/08 (20130101) H04L 63/0442 (20130101) H04L 67/10 (20130101) H04L 67/18 (20130101) H04L 2463/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439946 | Dinan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | INTEL CORPORATION (Santa Clara, California) |
| INVENTOR(S) | James Dinan (Hudson, Massachusetts); Mario Flajslik (Hudson, Massachusetts); Robert C. Zak (Bolton, Massachusetts) |
| ABSTRACT | Technologies for endpoint congestion avoidance are disclosed. In order to avoid congestion caused by a network fabric that can transport data to a compute device faster than the compute device can store the data in a particular type of memory, the compute device may in the illustrative embodiment determine a suitable data transfer rate and communicate an indication of the data transfer rate to the remote compute device which is sending the data. The remote compute device may then send the data at the indicated data transfer rate, thus avoiding congestion. |
| FILED | Friday, February 10, 2017 |
| APPL NO | 15/429716 |
| ART UNIT | 2468 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/10 (20130101) H04L 43/0894 (20130101) H04L 47/12 (20130101) H04L 47/25 (20130101) Original (OR) Class H04L 47/127 (20130101) H04L 67/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439975 | Cansever |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Derya Cansever (Havre de Grace, Maryland) |
| ABSTRACT | Priority assignment embodiments are discussed. In one embodiment, a system comprises a comparison component configured to make a first comparison of a first message of a message set against a mission with regard to a similarity of the first message to the mission to produce a first message similarity result and make a second comparison of a second message of the message set against the mission with regard to a similarity of the second message to the mission to produce a second message similarity result. The system also comprises a priority component configured to assign a transfer priority order among the first message and the second message through use of the first message similarity result and the second message similarity result, where the transfer priority order is based, at least in part, on the more similar a message is to the mission the higher priority given to the message. |
| FILED | Thursday, October 12, 2017 |
| APPL NO | 15/730790 |
| ART UNIT | 2455 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/026 (20130101) H04L 51/14 (20130101) H04L 51/16 (20130101) H04L 51/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10440054 | Robertson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vencore Labs, Inc. (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | Perspecta Labs Inc. (Basking Ridge, New Jersey) |
| INVENTOR(S) | Seth Robertson (Basking Ridge, New Jersey) |
| ABSTRACT | A method, computer program product, and system for generating a unique (deceptive) view of a network, the method includes a processor generating, for a host on a computing network, a virtual network topology view, where the virtual network topology view of the network host differs from a physical network topology of the computing network, wherein the network node perceives the computing network as comprising a network topology of the virtual network topology view. The generating includes: the processor modifying naming and addressing services of network components communicatively coupled to the network host and transforming network flows between the network resources viewable by the network host in the virtual network topology view, to be consistent with the virtual network topology view. |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/274855 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/4641 (20130101) H04L 41/12 (20130101) H04L 41/145 (20130101) H04L 41/0886 (20130101) H04L 61/103 (20130101) H04L 61/1511 (20130101) H04L 61/2007 (20130101) H04L 61/6022 (20130101) H04L 63/20 (20130101) H04L 63/0407 (20130101) H04L 63/1491 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10440055 | Allen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Patrick D. Allen (Columbia, Maryland); Steven A. Handy (Washington, District of Columbia); Aaron M. David (Elkridge, Maryland); James G. Castle (Olney, Maryland); Mark A. Matties (Ellicott City, Maryland) |
| ABSTRACT | An example apparatus configured to perform network deception may include processing circuitry configured to generate virtual instances of decoy resources residing within a defined host network for presentation to cyber attackers, control at least one software defined network switch to monitor network traffic directed to real and decoy resources of the defined host network, and route network traffic based on detected interactions with the decoy resources. The decoy resources may have differing levels of decoy fidelity, where decoy fidelity indicates a difficulty for a cyber attacker to determine that the resource is a decoy. Additionally, generating the virtual instances of decoy resources may be performed without modification to real assets or real services residing in the defined host network. Furthermore, decoy services may be made to appear on real network assets using software defined networking without modification to the real assets or real services residing in the defined host network. |
| FILED | Friday, July 28, 2017 |
| APPL NO | 15/662910 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 11/301 (20130101) G06F 21/552 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1425 (20130101) H04L 63/1491 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10440450 | Singh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ninoshka Krishan Singh (Somerville, Massachusetts); Joseph John Lacirignola (Beverly, Massachusetts); Christine Michelle Weston (Cambridge, Massachusetts); Andrew Peter Dumas (Somerville, Massachusetts); David Christopher Maurer (Stoneham, Massachusetts); David Francis Aubin, Jr. (Pelham, New Hampshire); Erik Metzger (Lincoln, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ninoshka Krishan Singh (Somerville, Massachusetts); Joseph John Lacirignola (Beverly, Massachusetts); Christine Michelle Weston (Cambridge, Massachusetts); Andrew Peter Dumas (Somerville, Massachusetts); David Christopher Maurer (Stoneham, Massachusetts); David Francis Aubin, Jr. (Pelham, New Hampshire); Erik Metzger (Lincoln, Massachusetts) |
| ABSTRACT | Described are systems, methods, and computer readable medium for dynamic power usage and data transfer rate management in a sensor network including synchronous and asynchronous links. Exemplary embodiments provide a lightweight communication protocol enabling dynamic management of data buffer size in a sensor network and corresponding control of power usage and data transfer rates in the sensor network. |
| FILED | Thursday, July 14, 2016 |
| APPL NO | 15/210581 |
| ART UNIT | 2465 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) H04L 67/26 (20130101) H04L 67/2814 (20130101) H04L 67/2823 (20130101) H04L 67/2833 (20130101) H04L 2012/5681 (20130101) Selecting H04Q 9/00 (20130101) Original (OR) Class H04Q 2209/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10440808 | Poenitzsch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southwest research Institute (San Antonio, Texas) |
| ASSIGNEE(S) | SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas) |
| INVENTOR(S) | Vasiliki Zorbas Poenitzsch (Alamo Heights, Texas); Ronghua Wei (San Antonio, Texas); Kent E. Coulter (Boerne, Texas); Edward Langa (San Antonio, Texas) |
| ABSTRACT | A method and system for generating a surface treating plasma. Gas is provided to a power conducting electrode and flows through the power conducting electrode. Power pulses are applied to the power conducting electrode in the range of 40 kW to 100 kW with a DC generator, at a frequency in the range of 1 Hz to 62.5 kHz, and with a pulse duration in the range of 0.1 microseconds to 3,000 microseconds. Peak currents in the range of 100 Amps to 400 Amps are produced and plasma is formed from the gas. A substrate surface may then be treated with the plasma. |
| FILED | Tuesday, November 17, 2015 |
| APPL NO | 14/944017 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) Original (OR) Class H05H 2001/4682 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10440810 | Lal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Amit Lal (Ithaca, New York); Yue Shi (Santa Clara, California); Serhan Ardanuc (Ithaca, New York); June-Ho Hwang (Ithaca, New York); Farhan Rana (Ithaca, New York) |
| ABSTRACT | A system that generates short charged particle packets or pulses (e.g., electron packets) without requiring a fast-switching-laser source is described. This system may include a charged particle source that produces a stream of continuous charged particles to propagate along a charged particle path. The system also includes a charged particle deflector positioned in the charged particle path to deflect the stream of continuous charged particles to a set of directions different from the charged particle path. The system additionally includes a series of beam blockers located downstream from the charged particle deflector and spaced from one another in a linear configuration as a beam-blocker grating. This beam-blocker grating can interact with the deflected stream of charged particles and divide the stream of the charged particles into a set of short particle packets. In one embodiment, the charged particles are electrons. The beam blockers can be conductors. |
| FILED | Monday, January 08, 2018 |
| APPL NO | 15/865056 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/06 (20130101) H01J 37/1472 (20130101) H01J 2237/15 (20130101) H01J 2237/063 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/04 (20130101) H05H 9/042 (20130101) H05H 9/045 (20130101) Original (OR) Class H05H 2007/043 (20130101) H05H 2007/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10434460 | Koech et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| INVENTOR(S) | Phillip K. Koech (Richland, Washington); Deepika Malhotra (Richland, Washington); David J. Heldebrant (Richland, Washington); Vassiliki-Alexandra Glezakou (Richland, Washington); Roger J. Rousseau (Richland, Washington); David C. Cantu (Reno, Nevada) |
| ABSTRACT | A class of water lean, organic solvents that can bind with various acid gasses to form acid gas bound molecules having a high degree of intramolecular hydrogen bonding which enables their use as regenerable solvents for acid gas capture. Unlike the other devices described in the prior art, the present invention takes advantage of shortened distances between the portions of the molecule that form hydrogen bonds within the structures when loaded with an acid gas so as to create a molecule with a higher internal bonding affinity and a reduced proclivity for agglomeration with other molecules. |
| FILED | Friday, October 05, 2018 |
| APPL NO | 16/153104 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/1425 (20130101) Original (OR) Class B01D 53/1456 (20130101) B01D 53/1493 (20130101) B01D 2252/2041 (20130101) B01D 2252/20426 (20130101) B01D 2252/20431 (20130101) B01D 2252/20457 (20130101) B01D 2257/302 (20130101) B01D 2257/308 (20130101) B01D 2257/504 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434498 | O'Keefe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| INVENTOR(S) | Matthew J. O'Keefe (Rolla, Missouri); Carlos E. Castano Londono (Rolla, Missouri); William G. Fahrenholtz (Rolla, Missouri) |
| ABSTRACT | Embodiments relate to a cerium-containing nano-coating composition, the composition including an amorphous matrix including one or more of cerium oxide, cerium hydroxide, and cerium phosphate; and crystalline regions including one or more of crystalline cerium oxide, crystalline cerium hydroxide, and crystalline cerium phosphate. The diameter of each crystalline region is less than about 50 nanometers. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/724389 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/10 (20130101) Original (OR) Class B01J 27/1804 (20130101) B01J 35/002 (20130101) B01J 35/004 (20130101) B01J 35/0006 (20130101) B01J 35/0013 (20130101) B01J 35/0033 (20130101) B01J 37/06 (20130101) B01J 37/28 (20130101) B01J 37/035 (20130101) B01J 37/0217 (20130101) B01J 37/0219 (20130101) B01J 37/0225 (20130101) B01J 37/0226 (20130101) B01J 37/345 (20130101) Alloys C22C 21/10 (20130101) C22C 21/12 (20130101) C22C 23/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 22/48 (20130101) C23C 22/56 (20130101) C23C 22/57 (20130101) C23C 22/73 (20130101) C23C 22/78 (20130101) C23C 22/83 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434542 | Dai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Xianming Dai (University Park, Pennsylvania); Birgitt M. Boschitsch (University Park, Pennsylvania); Jing Wang (University Park, Pennsylvania); Tak-Sing Wong (University Park, Pennsylvania); Nan Sun (University Park, Pennsylvania) |
| ABSTRACT | Substrates having a textured surface that can maintain or improve droplet mobility in both the Cassie and Wenzel states include a textured surface and a conformal lubricant layer thereover. The textured surface can include a plurality of raised first elements and a plurality of second elements thereon and the conformal lubricant layer over the plurality of raised first elements and covering the plurality of second elements. The plurality of raised first elements can have an average height of between 0.5 μm and 500 μm, and the plurality of second elements can have an average height of between 0.01 μm and 10 μm. Such substrates can be prepared by texturing a surface of a substrate with a plurality of raised first elements and a plurality of second elements thereon; optionally silanizing the textured surface and applying a lubricant layer over the plurality of raised first elements and between the plurality of second elements. |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/568639 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/00 (20130101) B05D 5/02 (20130101) B05D 5/08 (20130101) Original (OR) Class Cleaning in General; Prevention of Fouling in General B08B 17/065 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 59/022 (20130101) B29C 2059/023 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0092 (20130101) B29K 2995/0093 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434568 | Loukus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REL, Inc. (Calumet, Michigan) |
| ASSIGNEE(S) | LOUKUS TECHNOLOGIES, INC. (Calumet, Michigan) |
| INVENTOR(S) | Josh E. Loukus (Calumet, Michigan); Adam R. Loukus (Calumet, Michigan); Travis Pennala (Lyon, Michigan); Luke Luskin (Hubbell, Michigan) |
| ABSTRACT | Embodiments provide methods, apparatuses and systems for depositing a thermal insulator coating onto a desired surface of a mold cavity or insert or preform. Embodiments also provide casting methods using a thermal insulator coating. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 13/836001 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Foundry Moulding B22C 9/00 (20130101) Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 17/00 (20130101) B22D 17/22 (20130101) B22D 17/203 (20130101) B22D 17/2023 (20130101) B22D 19/02 (20130101) B22D 19/08 (20130101) B22D 19/14 (20130101) B22D 19/0081 (20130101) B22D 27/04 (20130101) Original (OR) Class Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/46 (20130101) C04B 30/02 (20130101) C04B 30/02 (20130101) C04B 2111/00525 (20130101) C04B 2111/00577 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24926 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434704 | Fenn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | David Robert Fenn (Allison Park, Pennsylvania); Kurt G. Olson (Gibsonia, Pennsylvania); Reza M. Rock (Pittsburgh, Pennsylvania); Cynthia Kutchko (Pittsburgh, Pennsylvania); Susan Donaldson (Allison Park, Pennsylvania); Anthony J. Fogl (Swissvale, Pennsylvania) |
| ABSTRACT | Methods of additive manufacture using coreactive components are disclosed. Thermosetting compositions for additive manufacturing are also disclosed. |
| FILED | Friday, August 18, 2017 |
| APPL NO | 15/680846 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/10 (20130101) C08G 18/10 (20130101) C08G 18/325 (20130101) C08G 18/755 (20130101) C08G 18/792 (20130101) C08G 18/3234 (20130101) C08G 18/3821 (20130101) C08G 18/3855 (20130101) C08G 18/4854 (20130101) C08G 18/5024 (20130101) C08G 18/6685 (20130101) C08G 59/66 (20130101) C08G 75/14 (20130101) C08G 75/045 (20130101) C08G 2150/50 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) C08K 3/36 (20130101) C08K 3/36 (20130101) C08K 3/046 (20170501) C08K 3/046 (20170501) Compositions of Macromolecular Compounds C08L 75/02 (20130101) C08L 81/02 (20130101) C08L 81/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 175/02 (20130101) C09D 175/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435343 | Marks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Tobin J. Marks (Evanston, Illinois); Massimiliano Delferro (Chicago, Illinois); Peter C. Stair (Northbrook, Illinois); Tracy L. Lohr (Evanston, Illinois); Aidan R. Mouat (Chicago, Illinois) |
| ABSTRACT | Catalytic preparation of hydrogen and aldehyde(s) from alcohols, including bioalcohols, without production of carbon monoxide or carbon dioxide. |
| FILED | Thursday, April 13, 2017 |
| APPL NO | 15/487017 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/28 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/02 (20130101) C01B 2203/1082 (20130101) C01B 2203/1223 (20130101) C01B 2203/1229 (20130101) Acyclic or Carbocyclic Compounds C07C 45/002 (20130101) Original (OR) Class C07C 45/002 (20130101) C07C 45/002 (20130101) C07C 47/04 (20130101) C07C 47/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435568 | Denton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SANDIA CORPORATION (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Michele L. Baca Denton (Bosque, New Mexico); Shawn M. Dirk (Albuquerque, New Mexico); Ross Stefan Johnson (Wilmington, Delaware) |
| ABSTRACT | The present invention relates to antifouling coatings capable of being switched by using heat or ultraviolet light. Prior to switching, the coating includes an onium cation component having antimicrobial and antibacterial properties. Upon switching, the coating is converted to a conjugated polymer state, and the cationic component is released with any adsorbed biofilm layer. Thus, the coatings herein have switchable and releasable properties. Methods of making and using such coatings are also described. |
| FILED | Monday, January 16, 2017 |
| APPL NO | 15/407164 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 31/04 (20130101) A01N 43/10 (20130101) A01N 55/02 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 3/065 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1637 (20130101) Original (OR) Class C09D 5/1693 (20130101) C09D 165/02 (20130101) C09D 183/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435642 | Qu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC. (Oak Ridge, Tennessee) |
| INVENTOR(S) | Jun Qu (Oak Ridge, Tennessee); Huimin Luo (Knoxville, Tennessee) |
| ABSTRACT | An ionic liquid composition having the following generic structural formula: wherein R1, R2, R3, and R4 are equivalent and selected from hydrocarbon groups containing at least three carbon atoms, and X− is a phosphorus-containing anion, particularly an organophosphate, organophosphonate, or organophosphinate anion, or a thio-substituted analog thereof containing hydrocarbon groups with at least three carbon atoms. Also described are lubricant compositions comprising the above ionic liquid and a base oil, wherein the ionic liquid is dissolved in the base oil. Further described are methods for applying the ionic liquid or lubricant composition onto a mechanical device for which lubrication is beneficial, with resulting improvement in friction reduction, wear rate, and/or corrosion inhibition. |
| FILED | Thursday, March 22, 2018 |
| APPL NO | 15/928362 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 137/04 (20130101) C10M 137/10 (20130101) C10M 137/12 (20130101) Original (OR) Class C10M 171/00 (20130101) C10M 2203/1025 (20130101) C10M 2203/1025 (20130101) C10M 2223/04 (20130101) C10M 2223/06 (20130101) C10M 2223/045 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2210/02 (20130101) C10N 2220/022 (20130101) C10N 2230/06 (20130101) C10N 2230/08 (20130101) C10N 2230/10 (20130101) C10N 2230/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435693 | Henard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Calvin A. Henard (Westminster, Colorado); Michael T. Guarnieri (Denver, Colorado) |
| ABSTRACT | Presented herein are biocatalysts and methods for converting C1-containing materials to organic acids such as muconic acid or adipic acid. |
| FILED | Wednesday, August 31, 2016 |
| APPL NO | 15/252648 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0069 (20130101) C12N 9/88 (20130101) C12N 9/1022 (20130101) C12N 9/1294 (20130101) C12N 15/52 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/44 (20130101) Enzymes C12Y 113/11001 (20130101) C12Y 202/01001 (20130101) C12Y 207/09002 (20130101) C12Y 401/01059 (20130101) C12Y 401/01063 (20130101) C12Y 401/02009 (20130101) C12Y 402/01118 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435770 | Gschneidner, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Karl A. Gschneidner, Jr. (Ames, Iowa); Frederick A. Schmidt (Ames, Iowa) |
| ABSTRACT | A carbothermic reduction method is provided for reducing a La-, Ce-, MM-, and/or Y-containing oxide in the presence of carbon and a source of a reactant element comprising Si, Ge, Sn, Pb, As, Sb, Bi, and/or P to form an intermediate alloy material including a majority of La, Ce, MM, and/or Y and a minor amount of the reactant element. The intermediate material is useful as a master alloy for in making negative electrode materials for a metal hydride battery, as hydrogen storage alloys, as master alloy additive for addition to a melt of commercial Mg and Al alloys, steels, cast irons, and superalloys; or in reducing Sm2O3 to Sm metal for use in Sm—Co permanent magnets. |
| FILED | Thursday, November 10, 2016 |
| APPL NO | 15/330895 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 1/00 (20130101) C22C 1/06 (20130101) Original (OR) Class C22C 28/00 (20130101) C22C 30/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) H01M 4/242 (20130101) H01M 4/383 (20130101) H01M 4/385 (20130101) H01M 4/662 (20130101) H01M 10/30 (20130101) H01M 10/345 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/124 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/54 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435803 | Kumta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Prashant N. Kumta (Pittsburgh, Pennsylvania); Karan Sandeep Kadakia (Pittsburgh, Pennsylvania); Moni Kanchan Datta (Pittsburgh, Pennsylvania); Oleg Velikokhatnyi (Pittsburgh, Pennsylvania); Prashanth Jampani Hanumantha (Pittsburgh, Pennsylvania) |
| ABSTRACT | The invention provides electro-catalyst compositions for an anode electrode of an acid mediated proton exchange membrane-based water electrolysis system. The compositions include a noble metal component selected from the group consisting of iridium oxide, ruthenium oxide, rhenium oxide and mixtures thereof, and a non-noble metal component selected from the group consisting of tantalum oxide, tin oxide, niobium oxide, titanium oxide, tungsten oxide, molybdenum oxide, yttrium oxide, scandium oxide, cooper oxide, zirconium oxide, nickel oxide and mixtures thereof. Further, the non-noble metal component can include a dopant. The dopant can be at least one element selected from Groups III, V, VI and VII of the Periodic Table. The compositions can be prepared using any solution based methods involving a surfactant approach or a sol gel approach. Further, the compositions are prepared using noble metal and non-noble metal precursors. Furthermore, a thin film containing the compositions can be deposited onto a substrate to form the anode electrode. |
| FILED | Wednesday, July 11, 2018 |
| APPL NO | 16/032139 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/10 (20130101) C25B 11/0405 (20130101) C25B 11/0484 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/881 (20130101) H01M 4/8828 (20130101) H01M 4/9016 (20130101) H01M 4/9075 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435812 | Han |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Jung Han (Woodbridge, Connecticut) |
| ABSTRACT | Methods are provided for generating a crystalline material. The methods comprise depositing a textured thin film in a growth seed area, wherein the textured thin film has a preferential crystallographic axis; providing a growth channel extending from the growth seed area, the growth channel permitting guided lateral growth; and growing a crystalline material in the growth channel along a direction that is substantially perpendicular to the preferential crystallographic axis of the textured thin film. A preferred crystalline material is gallium nitride, and preferred textured thin films are aluminum nitride and titanium nitride. |
| FILED | Tuesday, February 19, 2013 |
| APPL NO | 14/379088 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/16 (20130101) C30B 25/22 (20130101) C30B 25/186 (20130101) Original (OR) Class C30B 29/406 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/0262 (20130101) H01L 21/02422 (20130101) H01L 21/02439 (20130101) H01L 21/02458 (20130101) H01L 21/02623 (20130101) H01L 21/02639 (20130101) H01L 21/02647 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436005 | Mace et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Jonathan L. Mace (Los Alamos, New Mexico); Gerald J. Seitz (El Rancho, New Mexico); Lawrence E. Bronisz (Los Alamos, New Mexico) |
| ABSTRACT | Detonation control modules and detonation control circuits are provided herein. A trigger input signal can cause a detonation control module to trigger a detonator. A detonation control module can include a timing circuit, a light-producing diode such as a laser diode, an optically triggered diode, and a high-voltage capacitor. The trigger input signal can activate the timing circuit. The timing circuit can control activation of the light-producing diode. Activation of the light-producing diode illuminates and activates the optically triggered diode. The optically triggered diode can be coupled between the high-voltage capacitor and the detonator. Activation of the optically triggered diode causes a power pulse to be released from the high-voltage capacitor that triggers the detonator. |
| FILED | Thursday, September 29, 2016 |
| APPL NO | 15/279910 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 25/34 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/263 (20130101) Original (OR) Class E21B 43/1185 (20130101) E21B 47/123 (20130101) Ignition; Extinguishing-devices F23Q 21/00 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/02 (20130101) F42B 3/10 (20130101) F42B 3/24 (20130101) F42B 3/113 (20130101) F42B 3/182 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 15/42 (20130101) Blasting F42D 1/02 (20130101) F42D 1/05 (20130101) F42D 1/042 (20130101) F42D 1/045 (20130101) F42D 1/055 (20130101) F42D 3/00 (20130101) F42D 3/04 (20130101) F42D 3/06 (20130101) F42D 5/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436478 | Eisinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph Eisinger (Lakewood, Colorado); Kerry Manning (Lakewood, Colorado); Patrick Marcotte (Lakewood, Colorado); Nathan Stegall (Lakewood, Colorado) |
| ASSIGNEE(S) | Abengoa Solar LLC (Lakewood, Colorado) |
| INVENTOR(S) | Joseph Eisinger (Lakewood, Colorado); Kerry Manning (Lakewood, Colorado); Patrick Marcotte (Lakewood, Colorado); Nathan Stegall (Lakewood, Colorado) |
| ABSTRACT | Solar collector modules and techniques for their construction are disclosed. In one aspect, a solar collector module includes a reflector and a three-dimensional structural frame that supports the reflector. The structural frame includes a set of primary structural shapes and a set of axial frame members connected between corners of the primary structural shapes forming helical paths for the transmission of torque from one end of the structural frame to the other. In another aspect, a method for assembling a solar collector module includes pre-assembling part of the module. |
| FILED | Thursday, April 19, 2012 |
| APPL NO | 14/112017 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 53/02 (20130101) Structural Elements; Building Materials E04C 2003/0495 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 23/71 (20180501) Original (OR) Class F24S 23/74 (20180501) F24S 25/13 (20180501) F24S 25/60 (20180501) F24S 25/70 (20180501) F24S 30/425 (20180501) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/45 (20130101) Y02E 10/47 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49355 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436481 | Vetrovec |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jan Vetrovec (Larkspur, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jan Vetrovec (Larkspur, Colorado) |
| ABSTRACT | The invention is for an apparatus and method for a refrigerator and a heat pump based on the magnetocaloric effect (MCE) offering a simpler, lighter, robust, more compact, environmentally compatible, and energy efficient alternative to traditional vapor-compression devices. The subject magnetocaloric apparatus alternately exposes a suitable magnetocaloric material to strong and weak magnetic field while switching heat to and from the material by a mechanical commutator comprising heat pipe elements. The invention may be practiced with multiple magnetocaloric stages to attain large differences in temperature. Key applications include thermal management of electronics, as well as industrial and home refrigeration, heating, and air conditioning. The invention offers a simpler, lighter, compact, and robust apparatus compared to magnetocaloric devices of prior art. Furthermore, the invention may be run in reverse as a thermodynamic engine, receiving low-level heat and producing mechanical energy. |
| FILED | Monday, May 15, 2017 |
| APPL NO | 15/731270 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) F25B 23/006 (20130101) Original (OR) Class F25B 2321/0021 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/02 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436516 | Heung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Leung K. Heung (Aiken, South Carolina); Henry T. Sessions, Jr. (Aiken, South Carolina); Xin Xiao (Augusta, Georgia); Sharon H. Redd (North Augusta, South Carolina); David M. Immel (Augusta, Georgia) |
| ABSTRACT | Thermal cycling devices are provided. In one embodiment, a thermal cycling device includes a packed tube comprising an inlet portion defining an inlet and an outlet portion defining an outlet. The packed tube is provided in a double coil arrangement, wherein the double coil arrangement causes radially neighboring turns of the packed tube to have opposing flow directions therethrough. The thermal cycling device further includes a cooling device disposed axially adjacent to the packed tube, and a heating device disposed axially adjacent to the packed tube opposite the cooling device. |
| FILED | Friday, August 23, 2013 |
| APPL NO | 13/974525 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 59/00 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 7/04 (20130101) F28D 7/0016 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436519 | Longtin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Jon P. Longtin (Port Jefferson, New York) |
| ABSTRACT | Provided is a cocurrent loop thermosyphon system and method for operation thereof. The system includes a first rising tube having first and second ends; a condenser having first and second ends, with the first end connected to the second end of the first rising tube; a return tube having a first end connected to the second end of the condenser; a second rising tube having a first end connected to a second end of the return tube; a pump that pumps liquid within the second rising tube; and an evaporator having a first end connected to the second end of the second rising tube. The second end of the evaporator outputs vapor created by a change in state of the liquid to the first end of the first rising tube. |
| FILED | Friday, October 14, 2016 |
| APPL NO | 15/293723 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/06 (20130101) F28D 15/025 (20130101) F28D 15/0266 (20130101) Original (OR) Class F28D 2015/0291 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436721 | Kumar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UHV Technologies, Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | UHV Technologies, Inc. (Fort Worth, Texas) |
| INVENTOR(S) | Nalin Kumar (Fort Worth, Texas); Manuel Gerardo Garcia (Lexington, Kentucky) |
| ABSTRACT | A linear x-ray tube having one or more x-ray sources is configured for insertion into the soil in proximity to a root system of a plant for emission of an x-ray beam detected by a linear array of one or more x-ray detectors. The linear x-ray tube and detector array may be inserted into rhizotrons previously inserted into the soil. Various combinations of multiple x-ray tubes and/or detector arrays may be utilized to customize the x-ray imaging of the root system. |
| FILED | Friday, July 22, 2016 |
| APPL NO | 15/217011 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/046 (20130101) Original (OR) Class G01N 23/223 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/005 (20130101) G01V 5/0016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436745 | Star |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alexander Star (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Alexander Star (Pittsburgh, Pennsylvania) |
| ABSTRACT | A system for measuring pH includes a substrate and a sensor medium on the substrate. The sensor medium includes at least one oxidized carbon nanostructure and optionally at least one composition immobilized on the at least one oxidized carbon nanostructure. The at least one composition has at least one property that depends on pH. The system further includes at least one measurement system to measure a property of the sensor medium. |
| FILED | Wednesday, July 11, 2012 |
| APPL NO | 14/232138 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 99/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/80 (20130101) G01N 27/128 (20130101) G01N 27/4146 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/75 (20130101) Y10S 977/773 (20130101) Y10S 977/902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436919 | Dazeley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Steven Dazeley (San Leandro, California); Marc Bergevin (Pleasant Hill, California); Adam Bernstein (Palo Alto, California) |
| ABSTRACT | Nuclear reactors are emitters of a fundamental particle known as an antineutrino. The antineutrinos emitted as a result of nuclear fission reactions inside a reactor core carry information about those fission reactions. To detect the antineutrinos emitted by the nuclear reactor, the exemplary detector detects a positron event followed by a neutron event. The exemplary detector can also reconstruct the direction of the detected neutron to remove events produced by cosmogenic fast neutrons from the neutrons generated by the nuclear fission. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 15/920299 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 3/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10437736 | Basu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Arkaprava Basu (Austin, Texas); Eric Van Tassell (San Marcos, Texas); Mark Oskin (Clinton, Washington); Guilherme Cox (Highland Park, New Jersey); Gabriel Loh (Bellevue, Washington) |
| ABSTRACT | A data processing system includes a memory and an input output memory management unit that is connected to the memory. The input output memory management unit is adapted to receive batches of address translation requests. The input output memory management unit has instructions that identify, from among the batches of address translation requests, a later batch having a lower number of memory access requests than an earlier batch, and selectively schedules access to a page table walker for each address translation request of a batch. |
| FILED | Friday, December 22, 2017 |
| APPL NO | 15/852442 |
| ART UNIT | 2138 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3887 (20130101) G06F 9/4843 (20130101) G06F 12/1009 (20130101) Original (OR) Class G06F 12/1027 (20130101) G06F 13/4022 (20130101) G06F 13/4282 (20130101) G06F 2212/65 (20130101) G06F 2212/68 (20130101) G06F 2213/0026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438712 | DeGrado et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Timothy R. DeGrado (Rochester, Minnesota); Mukesh K. Pandey (Rochester, Minnesota); John Byrne (Boston, Massachusetts) |
| ABSTRACT | Methods of producing and isolating 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 13N, 52Mn, or 44Sc and solution targets for use in the methods are disclosed. The methods of producing 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 13N, 52Mn, or 44Sc include irradiating a closed target system with a proton beam. The closed target system can include a solution target. The methods of producing isolated 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 52Mn, or 44Sc further include isolating 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 52Mn, or 44Sc by ion exchange chromatography. An example solution target includes a target body including a target cavity for receiving the target material; a housing defining a passageway for directing a particle beam at the target cavity; a target window for covering an opening of the target cavity; and a coolant gas flow path disposed in the passageway upstream of the target window. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 15/493310 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Separation B01D 15/08 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/001 (20130101) G21G 1/10 (20130101) Original (OR) Class G21G 2001/0021 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438773 | Kobernik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PHOENIX LLC (Monona, Wisconsin) |
| ASSIGNEE(S) | PHOENIX LLC (Monona, Wisconsin) |
| INVENTOR(S) | Arne Kobernik (Monona, Wisconsin); Carl Sherven (Monona, Wisconsin); Casey Lamers (Monona, Wisconsin); Chris Seyfert (Monona, Wisconsin); Evan Sengbusch (Monona, Wisconsin); Gabriel Becerra (Monona, Wisconsin); Jin Lee (Monona, Wisconsin); Logan Campbell (Monona, Wisconsin); Mark Thomas (Monona, Wisconsin); Michael Taylor (Monona, Wisconsin); Preston Barrows (Monona, Wisconsin); Ross Radel (Monona, Wisconsin); Tye Gribb (Monona, Wisconsin) |
| ABSTRACT | Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196710 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/32082 (20130101) Original (OR) Class Spark Gaps; Overvoltage Arresters Using Spark Gaps; Sparking Plugs; Corona Devices; Generating Ions to be Introduced into Non-enclosed Gases H01T 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439121 | Samsonidze et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert Bosch GmbH (Stuttgart, Germany) |
| ASSIGNEE(S) | Robert Bosch GmbH (Stuttgart, Germany) |
| INVENTOR(S) | Georgy Samsonidze (Dorchester, Massachusetts); Boris Kozinsky (Waban, Massachusetts) |
| ABSTRACT | A thermoelectric power generation (TEG) unit configured to be integrated into the exhaust system of a vehicle includes a plurality of thermoelectric power generator modules, each comprising an electrically interconnected plurality of p-type and n-type thermoelectric material legs, each leg extending between a substrate on a hot side and a substrate on a cold side of the module, wherein the thermoelectric materials for the legs are half-Heusler compounds having a thermoelectric figure of merit (ZT) greater than 1.0. |
| FILED | Thursday, December 04, 2014 |
| APPL NO | 15/101116 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Alloys C22C 28/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/02 (20130101) H01L 35/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439123 | Fu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Liang Fu (Winchester, Massachusetts); Brian J. Skinner (Boston, Massachusetts) |
| ABSTRACT | A thermoelectric device includes a thermoelectrode characterized by a band gap less than kBT, where kB is the Boltzmann constant and T is a temperature of the thermoelectrode. The device also includes a magnetic field source, operably coupled to the thermoelectrode, to apply a magnetic field B on the thermoelectrode along a first direction. The device also includes a voltage source, operably coupled to the thermoelectrode, to apply an electric field E on the thermoelectrode along a second direction substantially perpendicular to the first direction so as to generate a heat flow along the second direction. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/012560 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/02 (20130101) H01L 35/14 (20130101) H01L 35/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439197 | Evans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ESS TECH, INC. (Portland, Oregon) |
| ASSIGNEE(S) | ESS Tech, Inc. (Portland, Oregon) |
| INVENTOR(S) | Craig Evans (West Linn, Oregon); Yang Song (West Linn, Oregon) |
| ABSTRACT | In one example, a system for a flow cell for a flow battery, comprising: a first flow field; and a polymeric frame, comprising: a top face; a bottom face, opposite the top face; a first side; a second side, opposite the first side; a first electrolyte inlet located on the top face and the first side of the polymeric frame; a first electrolyte outlet located on the top face and the second side of the polymeric frame; a first electrolyte inlet flow path located within the polymeric frame and coupled to the first electrolyte inlet; and a first electrolyte outlet flow path located within the polymeric frame and coupled to the first electrolyte outlet. In this way, shunt currents may be minimized by increasing the length and/or reducing the cross-sectional area of the electrolyte inlet and electrolyte outlet flow paths. |
| FILED | Friday, March 31, 2017 |
| APPL NO | 15/476795 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/361 (20130101) H01M 2/362 (20130101) Original (OR) Class H01M 8/20 (20130101) H01M 8/188 (20130101) H01M 8/04186 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/4757 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439219 | Elam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Jeffrey W. Elam (Elmhurst, Illinois); Xiangbo Meng (Naperville, Illinois) |
| ABSTRACT | A cathode for a lithium-sulfur battery includes a copper-containing current collector, over which an active material layer is disposed. A method of producing the cathode is provided. A lithium-sulfur battery including the cathode provides improved capacity and cycleability. |
| FILED | Friday, April 17, 2015 |
| APPL NO | 14/689997 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/38 (20130101) H01M 4/0404 (20130101) H01M 4/0471 (20130101) H01M 4/587 (20130101) H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 4/661 (20130101) H01M 4/5815 (20130101) Original (OR) Class H01M 10/052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439240 | Knudsen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert Bosch GmbH (Stuttgart, Germany); Edward Knudsen (Menlo Park, California); Paul Albertus (Washington, District of Columbia) |
| ASSIGNEE(S) | Robert Bosch GmbH (Stuttgart, Germany) |
| INVENTOR(S) | Edward Knudsen (Menlo Park, California); Paul Albertus (Washington, District of Columbia) |
| ABSTRACT | A flow battery system and method of operating the system minimizes performance losses. The flow battery system includes at least one cell, a first tank including a liquid electrolyte, a pump operably connected to the first tank and to the at least one cell, and a second electrolyte tank operably connected to the at least one cell. The flow battery system further includes a memory including program instructions stored therein, at least one sensor configured to a generate at least one signal associated with a sensed condition of the battery system, and a controller operably connected to the at least one sensor, the pump, and the memory and configured to execute the program instructions to determine a dead zone condition exists based upon the at least one signal, and control the pump to pulse flow of the liquid electrolyte to the at least one cell based upon the determination. |
| FILED | Friday, November 21, 2014 |
| APPL NO | 15/037828 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/20 (20130101) H01M 8/188 (20130101) H01M 8/0444 (20130101) H01M 8/04231 (20130101) H01M 8/04276 (20130101) Original (OR) Class H01M 8/04455 (20130101) H01M 8/04552 (20130101) H01M 8/04559 (20130101) H01M 8/04753 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439248 | Rahn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Christopher D. Rahn (State College, Pennsylvania); Charles E. Bakis (State College, Pennsylvania); Michael Hickner (State College, Pennsylvania); Yancheng Zhang (State College, Pennsylvania) |
| ABSTRACT | Systems and methods are disclosed for enhancing the construction and application of batteries by providing a battery system comprising at least one electrochemical panel with at least one electrochemical cell disposed therein, which is configured to enable multi-purpose functionality and applicability of the battery system. Embodiments provide for electrodes and/or current collectors of each electrochemical cell that are transversely orientated with respect to each face of an electrochemical panel. Some embodiments provide for a separator pouch disposed about at least one electrode and/or current collector to electrically insulate the electrode and/or current collector from a structure component of the device. Each electrochemical panel is configured to enable electrical communication with another electrochemical panel and/or an ancillary electric circuit. Each electrochemical panel is configured enable utilization thereof as a structural component of an ancillary structure. |
| FILED | Wednesday, November 26, 2014 |
| APPL NO | 15/111602 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/08 (20130101) H01M 2/18 (20130101) H01M 2/36 (20130101) H01M 2/365 (20130101) H01M 2/1653 (20130101) H01M 2/1686 (20130101) H01M 6/42 (20130101) H01M 10/04 (20130101) H01M 10/058 (20130101) H01M 10/0413 (20130101) Original (OR) Class H01M 10/0431 (20130101) H01M 10/0436 (20130101) H01M 10/0585 (20130101) H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439255 | Dvorsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | James E. Dvorsky (Plain City, Ohio); Steven M. Risser (Reynoldsburg, Ohio); James H. Saunders (Worthington, Ohio); Alexander C. Morrow (Gahanna, Ohio); David W. Nippa (Dublin, Ohio) |
| ABSTRACT | Light is transmitted through or from a separator of a battery cell or scattered within a battery cell and received by one or more light detectors. The light that is normally transmitted through the separator is scattered, absorbed, wavelength-shifted or otherwise distorted by an impending fault in the vicinity of or within the separator. The change in light due to the impending fault is measured by a detector and a signal from the detector is processed to identify the impending fault so that a warning can be generated indicative of the impending fault. |
| FILED | Friday, August 09, 2013 |
| APPL NO | 14/414984 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 1/07 (20130101) G01R 31/382 (20190101) G01R 31/396 (20190101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/14 (20130101) H01M 2/1606 (20130101) H01M 2/1653 (20130101) H01M 2/1666 (20130101) H01M 10/48 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439456 | Reddy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Patel Bhageerath Reddy (Niskayuna, New York); Kevin Michael Grace (Niskayuna, New York) |
| ABSTRACT | According to various embodiments, a synchronous reluctance machine is disclosed. The synchronous reluctance machine includes a stator, a synchronous reluctance rotor disposed within the stator and configured to rotate relative to the stator, and a non-magnetic sleeve disposed circumferentially around the rotor, where sleeve thickness is between about 1 mm and 2 mm and an air-gap radius is between about 80 mm and 100 mm. |
| FILED | Friday, December 02, 2016 |
| APPL NO | 15/367261 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 11/18 (20130101) Dynamo-electric Machines H02K 1/146 (20130101) H02K 1/246 (20130101) Original (OR) Class H02K 3/18 (20130101) H02K 19/103 (20130101) H02K 2201/03 (20130101) H02K 2213/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439513 | Cox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert Williams Cox (Charlotte, North Carolina); Daniel Wade Evans (Charlotte, North Carolina) |
| ASSIGNEE(S) | SINEWATTS, INC. (Charlotte, North Carolina); THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (Charlotte, North Carolina) |
| INVENTOR(S) | Robert Williams Cox (Charlotte, North Carolina); Daniel Wade Evans (Charlotte, North Carolina) |
| ABSTRACT | Various examples are directed to a converter system comprising first and second series-connected converter modules and a synchronization circuit. The synchronization circuit may modulate a reference signal onto a carrier signal to generate a synchronization current signal and the synchronization current signal to an output current of the converter system to generate an aggregated output current. A first converter module may receive the aggregated output current from a first current sensor and generate a first reproduced synchronization signal at least in part from the aggregated output current. A first switch control signal for switching at least one switch at the first converter may be generated based at least in part on the first reproduced synchronization signal. |
| FILED | Friday, December 18, 2015 |
| APPL NO | 15/528127 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/088 (20130101) H02M 3/285 (20130101) H02M 3/33569 (20130101) H02M 7/49 (20130101) Original (OR) Class H02M 7/493 (20130101) H02M 7/5383 (20130101) H02M 7/5395 (20130101) H02M 2001/0077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439517 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Zhong Lin Wang (Atlanta, Georgia); Zong-Hong Lin (Hsinchu, Taiwan); Gang Cheng (Atlanta, Georgia) |
| ABSTRACT | A generator for harvesting energy from flowing water is disclosed. The generator harvests electrostatic energy as well as mechanical kinetic energy from the flowing water. In one aspect, the generator includes a plurality of blades arranged in a radially outward fashion. Each blade includes an electrode and a surface layer for receiving flowing water carrying triboelectric charges. The flowing water affects a flow of electrons between the electrode and ground. In another aspect, the generator includes a first member with a first electrode, and a second member coupled to the first member about an axis. The second member includes a second electrode, and a surface layer between the first electrode and the second electrode. The second member is rotatable with respect to the axis to change triboelectric charges on the electrodes, and to affect a flow of electrons between the electrodes. |
| FILED | Tuesday, January 26, 2016 |
| APPL NO | 15/006865 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 1/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439538 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Deere and Company (Moline, Illinois) |
| ASSIGNEE(S) | DEERE and COMPANY (Moline, Illinois) |
| INVENTOR(S) | Dan Li (Fargo, North Dakota); Jacob Pence (Dubuque, Iowa); Long Wu (Fargo, North Dakota) |
| ABSTRACT | A motor has a rotor that rotates in response to one or more alternating current input signals. A position sensor is adapted to generate a substantially saw-tooth waveform indicative of a position of the rotor. A primary processing module or data processor is capable of providing position data and speed data for the rotor based on the substantially saw-tooth waveform. A notch filter can reject one or more selected frequency components in the substantially saw-tooth waveform to reduce distortion off the substantially saw-tooth waveform that would otherwise tend to cause inaccuracy in the provided position data and speed data. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/142645 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 11/225 (20160101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 23/18 (20160201) Original (OR) Class H02P 2203/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439817 | Choi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Sung Nam Choi (Sandia Park, New Mexico); Susan L. Washburn (Albuquerque, New Mexico); David John Zage (Fremont, California) |
| ABSTRACT | An authentication system, device and method that include ephemeral biometrics at login authentication is disclosed. The system, device and method may continue to authenticate the user while accessed to a user system. The system, device and method may also include position/location reporting of the device. |
| FILED | Thursday, October 10, 2013 |
| APPL NO | 14/051318 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3231 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10440862 | Iyengar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Madhusudan K. Iyengar (Woodstock, New York); Pritish R. Parida (Fishkill, New York); Mark D. Schultz (Ossining, New York) |
| ABSTRACT | A data center cooling system has an indoor portion wherein heat is absorbed from components in the data center, and an outdoor heat exchanger portion wherein outside air is used to cool a first heat transfer fluid (e.g., water) present in at least the outdoor heat exchanger portion of the cooling system during a first mode. When an appropriate time has been reached to switch from the first mode to a second mode, the outdoor heat exchanger portion of the data cooling system is switched to a second heat transfer fluid, which is a relatively low performance heat transfer fluid (compared to the first fluid). It has a second heat transfer fluid freezing point, lower than the first heat transfer fluid freezing point, and sufficiently low to operate without freezing when the outdoor air temperature drops below a first predetermined relationship with the first heat transfer fluid freezing point. |
| FILED | Monday, September 28, 2015 |
| APPL NO | 14/867199 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 25/005 (20130101) F25B 47/006 (20130101) F25B 2313/009 (20130101) F25B 2700/2106 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/00 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/2079 (20130101) H05K 7/20218 (20130101) H05K 7/20254 (20130101) H05K 7/20836 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10433754 | Nurmikko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
| INVENTOR(S) | Arto V. Nurmikko (Providence, Rhode Island); Ming Yin (Providence, Rhode Island); William R. Patterson (Rehoboth, Massachusetts); Juan Aceros (Providence, Rhode Island); David A. Borton (Providence, Rhode Island); Christopher W. Bull (Rehoboth, Massachusetts); Farah Laiwalla (Providence, Rhode Island) |
| ABSTRACT | Systems and methods for providing an electrical interface to a body are provided. In one embodiment, an implantable module is disclosed, comprising: an implantable electrode array, implantable within a body and capable of providing a plurality of communication channels for communicating electrical signals detected in a body; an amplifier circuit for processing electrical signals received from the electrode array; a wireless transceiver for sending and receiving telemetry data between the amplifier circuit and a wireless receiver located outside of the body; and a sealed enclosure that houses the amplifier circuit and the wireless transmitter and is biocompatible with surrounding tissue, the enclosure having a window that is transparent to a wireless medium used by the wireless transceiver. In another embodiment, a wireless transceiver and amplifier is detachably coupled to a transcutaneous attachment device, and the implantable electrode array is electrically coupled to the interface board via the transcutaneous attachment device. |
| FILED | Monday, September 16, 2013 |
| APPL NO | 14/028178 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0017 (20130101) A61B 5/0031 (20130101) A61B 5/0478 (20130101) Original (OR) Class A61B 5/04001 (20130101) A61B 5/6864 (20130101) A61B 5/6868 (20130101) A61B 2560/045 (20130101) A61B 2576/026 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/375 (20130101) A61N 1/0531 (20130101) A61N 1/3606 (20130101) A61N 1/3758 (20130101) A61N 1/3787 (20130101) A61N 1/36064 (20130101) A61N 1/36125 (20130101) A61N 1/37217 (20130101) A61N 1/37223 (20130101) A61N 1/37229 (20130101) A61N 1/37252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10434062 — Compositions and methods of making brittle-matrix particles through blister pack freezing
| US 10434062 | Johnston et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Keith P. Johnston (Austin, Texas); Joshua Engstrom (Spotswood, New Jersey); Jasmine Rowe (Austin, Texas); Alan B. Watts (Plainsboro, New Jersey); Robert O. Williams, III (Austin, Texas) |
| ABSTRACT | The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane droplets upon atomization and the templated floc compacts upon the evaporation of the hydrofluoroalkane propellant to form a porous particle for deep lung delivery. |
| FILED | Wednesday, August 29, 2018 |
| APPL NO | 16/115888 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434065 | Hood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Renee Hood (Baltimore, Maryland); Donald Lad DeVoe (Bethesda, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Renee Hood (Baltimore, Maryland); Donald Lad DeVoe (Bethesda, Maryland) |
| ABSTRACT | Microfluidic methods and systems are provided for continuous flow synthesis and active loading of liposomes, which include a liposome formation region configured to form a population of liposomes and a microdialysis region downstream from the liposome formation region and configured to form a transmembrane gradient for active drug loading of the liposomes. Microfluidic methods and systems for high throughput production of liposomes are also provided featuring high aspect ratio microchannels. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 15/456111 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1277 (20130101) Original (OR) Class A61K 9/1278 (20130101) A61K 31/00 (20130101) A61K 31/704 (20130101) A61K 31/5415 (20130101) A61K 31/7048 (20130101) A61K 31/7068 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/08 (20130101) B01J 19/0093 (20130101) B01J 2219/0086 (20130101) B01J 2219/00894 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434507 | Abate et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Adam R. Abate (San Francisco, California); Adam R. Sciambi (San Francisco, California); Russell Cole (San Francisco, California); Zev Jordan Gartner (Pacifica, California) |
| ABSTRACT | Methods for delivering discrete entities including, e.g., cells, media or reagents to substrates are provided. In certain aspects, the methods include manipulating and/or analyzing qualities of the entities or biological components thereof. In some embodiments, the methods may be used to create arrays of microenvironments and/or for two and three-dimensional printing of tissues or structures. Systems and devices for practicing the subject methods are also provided. |
| FILED | Wednesday, October 21, 2015 |
| APPL NO | 15/520056 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 2200/0673 (20130101) B01L 2300/0645 (20130101) B01L 2300/0829 (20130101) B01L 2300/0864 (20130101) B01L 2400/086 (20130101) B01L 2400/0427 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 15/1484 (20130101) G01N 2015/149 (20130101) G01N 2015/1006 (20130101) G01N 2035/1034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434542 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Xianming Dai (University Park, Pennsylvania); Birgitt M. Boschitsch (University Park, Pennsylvania); Jing Wang (University Park, Pennsylvania); Tak-Sing Wong (University Park, Pennsylvania); Nan Sun (University Park, Pennsylvania) |
| ABSTRACT | Substrates having a textured surface that can maintain or improve droplet mobility in both the Cassie and Wenzel states include a textured surface and a conformal lubricant layer thereover. The textured surface can include a plurality of raised first elements and a plurality of second elements thereon and the conformal lubricant layer over the plurality of raised first elements and covering the plurality of second elements. The plurality of raised first elements can have an average height of between 0.5 μm and 500 μm, and the plurality of second elements can have an average height of between 0.01 μm and 10 μm. Such substrates can be prepared by texturing a surface of a substrate with a plurality of raised first elements and a plurality of second elements thereon; optionally silanizing the textured surface and applying a lubricant layer over the plurality of raised first elements and between the plurality of second elements. |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/568639 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/00 (20130101) B05D 5/02 (20130101) B05D 5/08 (20130101) Original (OR) Class Cleaning in General; Prevention of Fouling in General B08B 17/065 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 59/022 (20130101) B29C 2059/023 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0092 (20130101) B29K 2995/0093 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435311 | Hristovski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kiril D. Hristovski (Gilbert, Arizona); Jasmina Markovski (Mesa, Arizona); Paul K. Westerhoff (Scottsdale, Arizona); Shahnawaz Sinha (Chandler, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Kiril D. Hristovski (Gilbert, Arizona); Jasmina Markovski (Mesa, Arizona); Paul K. Westerhoff (Scottsdale, Arizona); Shahnawaz Sinha (Chandler, Arizona) |
| ABSTRACT | Preparing a porous hybrid media includes contacting porous media (e.g., strong base ion-exchange media) with an aqueous solution including aluminum ions to yield a aluminum-ion-containing porous media, contacting the aluminum-ion containing porous media with a reducing agent to impregnate elemental aluminum in the porous media, and oxidizing the elemental aluminum to yield a porous hybrid media including aluminum hydr(oxide) impregnated in the porous media. In some cases, a pH of an aqueous mixture including the aluminum-ion-containing porous media may be adjusted to form a floc including aluminum hydroxide, and the aluminum hydroxide-containing porous media may be contacted with a reducing agent to yield a porous hybrid media including aluminum hydr(oxide) impregnated in the porous media. The porous hybrid media may advantageously be prepared at low temperature (e.g., room temperature). |
| FILED | Thursday, September 28, 2017 |
| APPL NO | 15/718074 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/08 (20130101) B01J 20/26 (20130101) B01J 20/3208 (20130101) B01J 20/3236 (20130101) B01J 20/28026 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/281 (20130101) C02F 1/285 (20130101) C02F 1/288 (20130101) Original (OR) Class C02F 2001/422 (20130101) C02F 2101/14 (20130101) C02F 2101/163 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435523 | James et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| ASSIGNEE(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| INVENTOR(S) | Susan P. James (Bellvue, Colorado); Min Zhang (Seattle, Washington); Guy Beauregard (Irvine, California); Rachael Kurkowski Oldinski (Seattle, Washington) |
| ABSTRACT | The present disclosure provides, inter alia, a method of producing an outer layer material for forming into a structure and that comprises an entanglement having a hydrophobic polymer host and a hydrophilic guest, including in one embodiment the steps of: intermingling cloaked hydrophilic guest complexes with the hydrophobic host; crosslinking molecules of the guest with the guest; and performing a hydrolysis reaction. |
| FILED | Thursday, December 22, 2016 |
| APPL NO | 15/388355 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/048 (20130101) Polysaccharides; Derivatives Thereof C08B 37/00 (20130101) C08B 37/0072 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/246 (20130101) Original (OR) Class C08J 9/42 (20130101) C08J 2323/06 (20130101) C08J 2405/08 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) C08L 5/08 (20130101) C08L 101/00 (20130101) C08L 2666/02 (20130101) C08L 2666/26 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249953 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435742 | Ju et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Zengmin Li (Flushing, New York); John Robert Edwards (St. Louis, Missouri); Yasuhiro Itagaki (New York, New York) |
| ABSTRACT | This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotide analogues which comprise unique labels attached to the nucleotide analogue through a cleavable linker, and a cleavable chemical group to cap the —OH group at the 3′-position of the deoxyribose. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/150185 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/11 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) C07H 19/14 (20130101) C07H 21/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6872 (20130101) C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/117 (20130101) C12Q 2525/186 (20130101) C12Q 2525/186 (20130101) C12Q 2535/101 (20130101) C12Q 2535/101 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2563/107 (20130101) C12Q 2563/107 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436570 | Kheyraddini-Mousavi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arash Kheyraddini-Mousavi (Albuquerque, New Mexico); Zayd Leseman (Albuquerque, New Mexico); Behnam Kheyraddini-Mousavi (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Arash Kheyraddini-Mousavi (Albuquerque, New Mexico); Zayd Leseman (Albuquerque, New Mexico); Behnam Kheyraddini-Mousavi (Albuquerque, New Mexico) |
| ABSTRACT | The present invention provides a Michelson interferometer for capturing images of a vibrating sample comprising a coherent light source. The light source may be adapted to illuminate a sample with a constant brightness across the sample. The interferometer may also be configured to generate a 3D representation of a sample using a single frame for a predetermined phase of the sample. The 3D representations may be combined to create a 3D video representation of the vibrating sample. |
| FILED | Monday, November 07, 2016 |
| APPL NO | 15/330822 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02012 (20130101) G01B 9/02038 (20130101) Original (OR) Class G01B 9/02041 (20130101) G01B 9/02097 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0056 (20130101) G02B 21/082 (20130101) G02B 21/0084 (20130101) G02B 27/0927 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436615 | Agarwal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Yuvraj Agarwal (Pittsburgh, Pennsylvania); Christopher Harrison (Pittsburgh, Pennsylvania); Gierad Laput (Pittsburgh, Pennsylvania); Sudershan Boovaraghavan (Pittsburgh, Pennsylvania); Chen Chen (Pittsburgh, Pennsylvania); Abhijit Hota (Pittsburgh, Pennsylvania); Bo Robert Xiao (Pittsburgh, Pennsylvania); Yang Zhang (Pittsburgh, Pennsylvania) |
| ABSTRACT | A sensing system includes a sensor assembly that is communicably connected to a computer system, such as a server or a cloud computing system. The sensor assembly includes a plurality of sensors that sense a variety of different physical phenomena. The sensor assembly featurizes the raw sensor data and transmits the featurized data to the computer system. Through machine learning, the computer system then trains a classifier to serve as a virtual sensor for an event that is correlated to the data from one or more sensor streams within the featurized sensor data. The virtual sensor can then subscribe to the relevant sensor feeds from the sensor assembly and monitor for subsequent occurrences of the event. Higher order virtual sensors can receive the outputs from lower order virtual sensors to infer nonbinary details about the environment in which the sensor assemblies are located. |
| FILED | Tuesday, April 24, 2018 |
| APPL NO | 15/961537 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/00 (20130101) G01D 9/005 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/2823 (20130101) H04L 67/12 (20130101) Wireless Communication Networks H04W 4/38 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436650 | Maurer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Peter Christian Maurer (Boston, Massachusetts); Hyun Ji Noh (Boston, Massachusetts); Georg Kucsko (Cambridge, Massachusetts); Mikhail D. Lukin (Cambridge, Massachusetts); Hongkun Park (Lexington, Massachusetts); Minako Kubo (Cambridge, Massachusetts) |
| ABSTRACT | An approach to nanoscale thermometry that utilizes coherent manipulation of the electronic spin associated with nitrogen-vacancy (NV) color centers in diamond is disclosed. The methods and apparatus allow for detection of temperature variations down to milli-Kelvin resolution, at nanometer length scales. This biologically compatible approach to thermometry offers superior temperature sensitivity and reproducibility with a reduced measurement time. The disclosed apparatus can be used to study heat-generating intracellular processes. |
| FILED | Tuesday, April 01, 2014 |
| APPL NO | 14/781382 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/32 (20130101) Original (OR) Class G01K 11/20 (20130101) G01K 13/00 (20130101) G01K 2211/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436795 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Institute for Cancer Research (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Hong Cheng (Philadelphia, Pennsylvania); Heinrich Roder (Philadelphia, Pennsylvania) |
| ABSTRACT | Carbon-detected NMR is well-suited for mapping binding sites in intrinsically disordered regions of a polypeptides, and for mapping of binding motifs in intrinsically disordered regions with single-residue resolution. Provided are methods of carbon-detected NMR for determining the amino acids that mediate the interaction between an intrinsically disordered polypeptide or protein, or an intrinsically disordered region of a polypeptide, and a biomolecule such as another polypeptide or a nucleic acid. |
| FILED | Thursday, September 14, 2017 |
| APPL NO | 15/704852 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/088 (20130101) G01N 33/6854 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10437627 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Binghamton, New York) |
| INVENTOR(S) | Yaohui Hu (Binghamton, New York); Kartik Gopalan (Vestal, New York) |
| ABSTRACT | Standard nested virtualization allows a hypervisor to run other hypervisors as guests, i.e. a level-0 (L0) hypervisor can run multiple level-1 (L1) hypervisors, each of which can run multiple level-2 (L2) virtual machines (VMs), with each L2 VM is restricted to run on only one L1 hypervisor. Span provides a Multi-hypervisor VM in which a single VM can simultaneously run on multiple hypervisors, which permits a VM to benefit from different services provided by multiple hypervisors that co-exist on a single physical machine. Span allows (a) the memory footprint of the VM to be shared across two hypervisors, and (b) the responsibility for CPU and I/O scheduling to be distributed among the two hypervisors. Span VMs can achieve performance comparable to traditional (single-hypervisor) nested VMs for common benchmarks. |
| FILED | Monday, October 23, 2017 |
| APPL NO | 15/790751 |
| ART UNIT | 2196 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) Original (OR) Class G06F 2009/4557 (20130101) G06F 2009/45579 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10437993 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
| INVENTOR(S) | Ang Chen (Philadelphia, Pennsylvania); Hanjun Xiao (Philadelphia, Pennsylvania); William Bradley Moore (Washington, District of Columbia); Andreas Haeberlen (Philadelphia, Pennsylvania); Linh Thi Xuan Phan (Philadelphia, Pennsylvania); Micah Sherr (Silver Spring, Maryland); Wenchao Zhou (Vienna, Virginia) |
| ABSTRACT | A mechanism called time-deterministic replay (TOR) that can reproduce the execution of a program, including its precise timing. Without TOR, reproducing the timing of an execution is difficult because there are many sources of timing variability. TOR uses a combination of techniques to either mitigate or eliminate most of these sources of variability. Using a prototype implementation of TOR in a Java Virtual Machine, we show it is possible to reproduce the timing to within 1.85% of the original execution. A study of one of the applications of TOR is described: the detection of a covert timing channel. Timing channels can be used to exfiltrate information from a compromised machine by subtly varying timing of the machine's outputs, TOR can detect this variation. Unlike prior solutions, which generally look for a specific type of timing channel, our approach can detect a wide variety of channels with high accuracy. |
| FILED | Monday, October 05, 2015 |
| APPL NO | 15/514820 |
| ART UNIT | 2492 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) G06F 21/12 (20130101) G06F 21/53 (20130101) G06F 21/75 (20130101) G06F 21/556 (20130101) Original (OR) Class G06F 2009/45587 (20130101) G06F 2221/033 (20130101) G06F 2221/2151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438626 | Nealey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); HGST Netherlands B.V. (Amsterdam, Netherlands) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); WESTERN DIGITAL TECHNOLOGIES (San Jose, California) |
| INVENTOR(S) | Paul F. Nealey (Chicago, Illinois); Huiman Kang (Madison, Wisconsin); Francois Detcheverry (Madison, Wisconsin); Juan J. de Pablo (Chicago, Illinois); Ricardo Ruiz (Santa Clara, California); Thomas Albrecht (San Jose, California) |
| ABSTRACT | Methods to pattern substrates with dense periodic nanostructures that combine top-down lithographic tools and self-assembling block copolymer materials are provided. According to various embodiments, the methods involve chemically patterning a substrate, depositing a block copolymer film on the chemically patterned imaging layer, and allowing the block copolymer to self-assemble in the presence of the chemically patterned substrate, thereby producing a pattern in the block copolymer film that is improved over the substrate pattern in terms feature size, shape, and uniformity, as well as regular spacing between arrays of features and between the features within each array compared to the substrate pattern. In certain embodiments, the density and total number of pattern features in the block copolymer film is also increased. High density and quality nanoimprint templates and other nanopatterned structures are also provided. |
| FILED | Monday, November 09, 2015 |
| APPL NO | 14/935914 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 5/00 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00031 (20130101) B81C 2201/0149 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 5/82 (20130101) G11B 5/84 (20130101) Original (OR) Class G11B 5/743 (20130101) G11B 5/746 (20130101) G11B 5/855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439433 | Golshani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Amir Golshani (Orlando, Florida); Wei Sun (Oviedo, Florida); Qun Zhou (Oviedo, Florida) |
| ABSTRACT | A method of self-healing power grids after power outages includes providing an Adaptive Restoration Decision Support System (ARDSS) for generating a restoration solution using static and dynamic input data from power generator(s) powering transmission lines, from the transmission lines and loads. At a beginning of a restoration period a two-stage problem is solved including a first and second-stage problem with an optimal planning (OP) function as a mixed-integer linear programming (MILP) problem using initial static and dynamic data to determine start-up times for the power generator and energization sequences for transmission lines involved in the power outage. Only the second-stage problem is again solved with an optimal real-time (OR) function using the start-up times and energization sequences along with updated static and dynamic data to determine operating parameters for the grid. The restoration solution is implemented over restoration time steps until all loads involved in the power outage are recovered. |
| FILED | Thursday, March 01, 2018 |
| APPL NO | 15/909062 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0631 (20130101) G06Q 50/06 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/006 (20130101) H02J 3/06 (20130101) H02J 13/0048 (20130101) Original (OR) Class H02J 13/0072 (20130101) H02J 13/0075 (20130101) H02J 2003/001 (20130101) H02J 2003/003 (20130101) H02J 2003/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439755 | Krunz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Marwan M. Krunz (Tucson, Arizona); Berk Akgun (Tucson, Arizona); Peyman Siyari (Tucson, Arizona); Hanif Rahbari (Tucson, Arizona); Rashad Mohamed Eletreby (Tucson, Arizona); Onur Ozan Koyluoglu (Tucson, Arizona) |
| ABSTRACT | Systems and methods of friendly jamming for securing wireless communications at the physical layer are presented. Under the assumption of exact knowledge of the eavesdropping channel, a resource-efficient distributed approach is used to improve the secrecy sum-rate of a multi-link network with one or more eavesdroppers while satisfying an information-rate constraint for all links. A method based on mixed strategic games can offer robust solutions to the distributed secrecy sum-rate maximization. In addition, a block fading broadcast channel with a multi-antenna transmitter, sending two or more independent confidential data streams to two or more respective users in the presence of a passive eavesdropper is considered. Lastly, a per-link strategy is considered and an optimization problem is formulated, which aims at jointly optimizing the power allocation and placement of the friendly jamming devices for a given link under secrecy constraints. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/012620 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 1/12 (20130101) Secret Communication; Jamming of Communication H04K 3/60 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10440553 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sai Zhang (Wuhan, China PRC); Cihan Tepedelenlioglu (Chandler, Arizona); Andreas Spanias (Tempe, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Sai Zhang (Wuhan, China PRC); Cihan Tepedelenlioglu (Chandler, Arizona); Andreas Spanias (Tempe, Arizona) |
| ABSTRACT | Some embodiments include a wireless sensor network including a plurality of sensor nodes each comprising: a signal receiver configured to receive intermediate information from at least one of one or more neighboring nodes of the plurality of sensor nodes, one or more processors configured to receive the intermediate information and update the intermediate information based on a soft-max approximation function, and a transmitter configured to send the intermediate information, as updated, to at least one of the one or more neighboring nodes of the plurality of sensor nodes. For each sensor node of the plurality of sensor nodes: the sensor node can store local location coordinates for the sensor node, and the sensor node can be devoid of receiving location coordinates for any other of the plurality of sensor nodes. The plurality of sensor nodes can be configured to communicate in a distributed manner for a first plurality of iterations until a final iteration of the first plurality of iterations when a predetermined stopping condition is satisfied. The plurality of sensor nodes can be further configured to generate an estimated center of the wireless sensor network based on the intermediate information updated in the final iteration of the first plurality of iterations. The wireless sensor network can be devoid of a fusion center. Other embodiments are disclosed. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 15/995433 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) Wireless Communication Networks H04W 4/38 (20180201) H04W 8/005 (20130101) Original (OR) Class H04W 8/14 (20130101) H04W 24/02 (20130101) H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10435293 | Kang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jin Ho Kang (Newport News, Virginia); Cheol Park (Yorktown, Virginia); Joycelyn S. Harrison (Hampton, Virginia); Michael W. Smith (Newport News, Virginia); Sharon E. Lowther (Arlington, Virginia); Jae-Woo Kim (Newport News, Virginia); Godfrey Sauti (Hampton, Virginia) |
| ASSIGNEE(S) | National Institute of Aerospace Associates (Hampton, Virginia); The United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Jin Ho Kang (Newport News, Virginia); Cheol Park (Yorktown, Virginia); Joycelyn S. Harrison (Hampton, Virginia); Michael W. Smith (Newport News, Virginia); Sharon E. Lowther (Arlington, Virginia); Jae-Woo Kim (Newport News, Virginia); Godfrey Sauti (Hampton, Virginia) |
| ABSTRACT | Formation of a boron nitride nanotube nanocomposite film by combining a boron nitride nanotube solution with a matrix such as a polymer or a ceramic to form a boron nitride nanotube/polyimide mixture and synthesizing a boron nitride nanotube/polyimide nanocomposite film as an electroactive layer. |
| FILED | Wednesday, October 13, 2010 |
| APPL NO | 12/925047 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 29/14 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/00 (20130101) H01L 41/37 (20130101) H01L 41/082 (20130101) H01L 41/293 (20130101) H01L 41/0805 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/42 (20150115) Y10T 29/49002 (20150115) Y10T 29/49005 (20150115) Y10T 29/49155 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436612 | Ford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Kevin Ford (Middletown, Connecticut); Eli Warren (Wethersfield, Connecticut); Corey A. Benoit (Uncasville, Connecticut); Edward F Dreger (Burlington, Connecticut); Erik D. Rice (Lebanon, Connecticut); Mark W. Costa (Storrs, Connecticut) |
| ABSTRACT | A capacitance probe monitors the distance between a blade tip and a fan, compressor or turbine case. The capacitance probe may be attached to a liner, and may travel with the liner as it radially expands due to thermal changes. The capacitance probe may include a circuit board sensor with a metallic plate, and one or more capacitors. The metallic plate may be encapsulated within an insulating material. A plurality of soft leads may be in electrical communication with the circuit board sensor, allowing a lower lead weight, reduced size and increased flexibility. The soft leads may also be embedded in the liner. In this way, the capacitance probe can record more accurate distance measurements and promote a gas turbine engine's continued and efficient operation. |
| FILED | Wednesday, October 21, 2015 |
| APPL NO | 14/919225 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 11/20 (20130101) F01D 17/02 (20130101) F01D 21/003 (20130101) F01D 25/24 (20130101) Non-positive-displacement Pumps F04D 29/321 (20130101) F04D 29/325 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/83 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/14 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/2417 (20130101) Original (OR) Class Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436680 | Peyvan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kianoosh Peyvan (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kianoosh Peyvan (Seattle, Washington) |
| ABSTRACT | A cell capture, disruption, and extraction apparatus includes a disruption chamber configured to receive cell solution and having therein a plurality of abrasives, which can include diamond powder, variably and multi dimensionally disbursed therein, and a pestle positioned in the disruption chamber. The apparatus includes an actuation device configured to agitate the disruption chamber and/or pestle, movement of the abrasives tearing cell structure in the solution to access its contents. A binding column or size exclusion column can be positioned downstream of the disruption chamber. The pestle can rotate with respect to the disruption chamber. The pestle can include a nut-shaped core or axle, and/or include a plurality of extrusions. Cell solution can first be introduced in the disruption chamber, the abrasives capturing the cells and allowing therethrough and purging the waste content, then breaking the cell content through the foregoing agitation process. The lysate can then bind to an extraction matrix downstream of the disruption chamber or it can be mixed in with the abrasives. |
| FILED | Saturday, October 11, 2014 |
| APPL NO | 14/512428 |
| ART UNIT | 1799 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) Original (OR) Class G01N 2001/2866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10436957 | Tabirian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beam Engineering for Advanced Measurements Co. (Orlando, Florida) |
| ASSIGNEE(S) | Beam Engineering for Advanced Measurements Co. (Orlando, Florida) |
| INVENTOR(S) | Nelson V. Tabirian (Winter Park, Florida); Zhi J. Liao (Apopka, Florida); David E. Roberts (Apopka, Florida) |
| ABSTRACT | Diffractive waveplate lenses, mirrors, devices, systems and methods for performing imaging over a broad spectral band in imaging systems, such as but not limited to astronomical imaging, surveillance imaging, and in communication systems, such as laser communication systems. Corrector mirrors are used with a flat diffractive wave diffractive waveplate lens so that chromatic aberrations of the diffractive waveplate lens are reduced with the imaging system. |
| FILED | Thursday, October 27, 2016 |
| APPL NO | 15/336336 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/10 (20130101) G02B 5/1833 (20130101) Original (OR) Class G02B 5/1842 (20130101) G02B 5/3083 (20130101) G02B 7/02 (20130101) G02B 7/003 (20130101) G02B 7/1822 (20130101) G02B 13/0055 (20130101) G02B 23/02 (20130101) G02B 27/0012 (20130101) G02B 27/0037 (20130101) G02B 27/4211 (20130101) G02B 27/4261 (20130101) G02B 27/4288 (20130101) Holographic Processes or Apparatus G03H 2001/0816 (20130101) G03H 2240/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439212 | Bugga et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Ratnakumar V. Bugga (Arcadia, California); Candace S. Seu (La Jolla, California) |
| ABSTRACT | Composite cathode materials are provided herein. Disclosed composite cathode materials include those comprising an aluminum borate coating. Systems making use of the cathode active materials are also described, such as electrochemical cells and electrodes for use in electrochemical cells. Methods for making and using the composite cathode materials are also disclosed. |
| FILED | Friday, July 08, 2016 |
| APPL NO | 15/206080 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) Original (OR) Class H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/628 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10437311 | Chuang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Pierce I. Chuang (Briarcliff Manor, New York); Divya Pathak (Philadelphia, Pennsylvania); Phillip J. Restle (Katonah, New York); Christos Vezyrtzis (Elmsford, New York) |
| ABSTRACT | A voltage droop mitigation system, that includes a first processor core that executes computer executable components stored in a memory. A time-based sensor component generates digital data representing voltage values associated with a power supply. A filtering component digitally conditions the generated digital data, and an analysis component analyzes the conditioned data and determines slope of the power supply voltage and employs counters to determine rate of data change over time; and if the slope is negative and exceeds a first pre-determined value for a pre-determined time period. The system implements one or more voltage droop-reduction techniques at the first processor core; and the first processor core transmits at least one of the following types of information: its voltage value, slope information or decision to apply droop reduction to one or more other cores. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/257047 |
| ART UNIT | 2187 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/305 (20130101) G06F 1/324 (20130101) Original (OR) Class G06F 1/3296 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439733 | Sluz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Joseph E. Sluz (Ellicott City, Maryland); Michael L. Dennis (Ellicott City, Maryland); Eric J. Adles (Ellicott City, Maryland); Raymond M. Sova (Reisterstown, Maryland); Chun-Huei Bair (Silver Spring, Maryland); Darrell A. Zinn (Clarksville, Maryland); Edward H. Darlington (Jessup, Maryland) |
| ABSTRACT | An optical circuit breaker includes a main optical transmission path including an optical coupler, a delay line and a protection device, and a parallel protection path configured to receive a tapped portion of a signal provided to the main optical transmission path and generate a reference signal based on the tapped portion. The protection device may be configured to be triggered to prevent an overpower condition from passing through the optical circuit breaker responsive to the reference signal exceeding a user selectable threshold. The delay line may be configured to have a longer delay than a time it takes for the protection device to be triggered via the parallel protection path. |
| FILED | Thursday, January 08, 2015 |
| APPL NO | 14/591948 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Transmission H04B 10/032 (20130101) H04B 10/67 (20130101) Original (OR) Class H04B 10/672 (20130101) H04B 10/0795 (20130101) H04B 10/07955 (20130101) Multiplex Communication H04J 14/0294 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10439946 | Dinan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | INTEL CORPORATION (Santa Clara, California) |
| INVENTOR(S) | James Dinan (Hudson, Massachusetts); Mario Flajslik (Hudson, Massachusetts); Robert C. Zak (Bolton, Massachusetts) |
| ABSTRACT | Technologies for endpoint congestion avoidance are disclosed. In order to avoid congestion caused by a network fabric that can transport data to a compute device faster than the compute device can store the data in a particular type of memory, the compute device may in the illustrative embodiment determine a suitable data transfer rate and communicate an indication of the data transfer rate to the remote compute device which is sending the data. The remote compute device may then send the data at the indicated data transfer rate, thus avoiding congestion. |
| FILED | Friday, February 10, 2017 |
| APPL NO | 15/429716 |
| ART UNIT | 2468 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/10 (20130101) H04L 43/0894 (20130101) H04L 47/12 (20130101) H04L 47/25 (20130101) Original (OR) Class H04L 47/127 (20130101) H04L 67/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10434171 | Mauldin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Mauldin (Loveland, Colorado); Doug Eckery (Fort Collins, Colorado); Lowell Miller (Greeley, Colorado) |
| ABSTRACT | A vaccine adjuvant and immunogenic composition may be described herein. The vaccine adjuvant may comprise cell wall fragments of the genus Mycobacterium, and more particularly, of M. avium. The immunogenic composition may include the vaccine adjuvant conjugated to an antigen. For example, cell wall fragments of M. avium (herein also referred to as MAF) may be conjugated to an antigen targeting Gonadotropin releasing hormone (GnRH). The MAF-antigen conjugate may be delivered for the purposes of treatment through one of several methods, including intramuscular injection, naso-pharyngeal, or oral. |
| FILED | Monday, December 18, 2017 |
| APPL NO | 15/845306 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 39/04 (20130101) A61K 39/0006 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/552 (20130101) A61K 2039/6068 (20130101) A61K 2039/55594 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/16 (20180101) A61P 15/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10435557 | Orts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Wahington, District of Columbia); Lapol LLC (Santa Barbara, California) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Lapol, LLC (Santa Barbara, California) |
| INVENTOR(S) | William J. Orts (Burlingame, California); Lennard F. Torres (Dublin, California); Allison Flynn (El Cerrito, California); William Kelly (Grand Rapids, Michigan) |
| ABSTRACT | Stereocomplex biopolymer compositions having tunable and improved mechanical properties and methods of making such compositions are disclosed. The biopolymer compositions include combinations of a matrix-forming polylactic acid comprising an essentially pure enantiomer and a tough polyester to form a polylactic acid matrix. The polylactic acid matrix is further combined with a base polylactic acid comprising an essentially pure opposite enantiomer of the first essentially pure enantiomer of the matrix-forming polylactic acid to form the stereocomplex. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 15/469204 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/005 (20130101) C08J 2367/04 (20130101) C08J 2467/02 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) Original (OR) Class C08L 2201/08 (20130101) C08L 2205/03 (20130101) C08L 2205/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10435775 | Forbes Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ATI PROPERTIES LLC (Albany, Oregon) |
| ASSIGNEE(S) | ATI PROPERTIES LLC (Albany, Oregon) |
| INVENTOR(S) | Robin M. Forbes Jones (Charlotte, North Carolina); John V. Mantione (Indian Trail, North Carolina); Urban J. DeSouza (Ann Arbor, Michigan); Jean-Philippe Thomas (Charlotte, North Carolina); Ramesh S. Minisandram (Charlotte, North Carolina); Richard L. Kennedy (Monroe, North Carolina); R. Mark Davis (Marshville, North Carolina) |
| ABSTRACT | Methods of refining the grain size of titanium and titanium alloys include multiple upset and draw forging. Titanium and titanium alloy workpieces are heated to a workpiece forging temperature within a workpiece forging temperature range in the alpha+beta phase field. The workpiece may comprise a starting cross-sectional dimension. The workpiece is upset forged in the workpiece forging temperature range. After upsetting, the workpiece is multiple pass draw forged in the workpiece forging temperature range. Multiple pass draw forging may comprise incrementally rotating the workpiece in a rotational direction followed by draw forging the workpiece after each incremental rotation. Incrementally rotating and draw forging the workpiece is repeated until the workpiece comprises substantially the same starting cross-sectional dimension. |
| FILED | Tuesday, September 17, 2013 |
| APPL NO | 14/028588 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Forging; Hammering; Pressing Metal; Riveting; Forge Furnaces B21J 1/003 (20130101) B21J 1/06 (20130101) B21J 1/025 (20130101) Alloys C22C 14/00 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/183 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10438788 | Murphy |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NOAA Technology Partnerships Office (Silver Spring, Maryland) |
| ASSIGNEE(S) | NOAA Technology Partnerships Office (Silver Spring, Maryland) |
| INVENTOR(S) | Daniel Murphy (Boulder, Colorado) |
| ABSTRACT | A system for expressing an ion path in a time-of-flight (TOF) mass spectrometer. The present invention uses two successive curved sectors, with the second one reversed, to form S-shaped configuration such that an output ion beam is parallel to an input ion beam, such that the ions makes two identical but opposed turns, and such that the geometry of the entire system folds into a very compact volume. Geometry of a TOF mass spectrometer system in accordance with embodiments of the present invention further includes straight drift regions positioned before and after the S-shaped configuration and, optionally, a short straight region positioned between the two curved sectors with total length equal to about the length of the central arc of both curved sectors. |
| FILED | Monday, November 12, 2018 |
| APPL NO | 16/186821 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/408 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10434188 | Trippel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Indiana University (Indianapolis, Indiana); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Indianapolis, Indiana); UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Stephen B. Trippel (Indianapolis, Indiana); Shuiliang Shi (Carmel, Indiana) |
| ABSTRACT | The present invention provides fusion proteins including a hyaluronic acid-binding domain of a cartilage matrix protein and a conserved region of a growth factor protein. Certain embodiments provide nucleic nucleic acid sequences encoding a fusion protein and compositions thereof. Methods for using fusion polypeptides and nucleic acid molecules discloses herein are also provided. In certain embodiments, the fusion proteins and/or nucleic acid molecules can be used to treat a cartilage matrix protein-related condition in a subject. |
| FILED | Tuesday, June 03, 2014 |
| APPL NO | 14/294305 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) Original (OR) Class Peptides C07K 14/65 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10434319 | Narayan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); TOPERA, INC. (Menlo Park, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia); Topera, Inc. (Menlo Park, California) |
| INVENTOR(S) | Sanjiv M. Narayan (Palo Alto, California); Carey Robert Briggs (La Jolla, California); Ruchir Sehra (Scottsdale, Arizona) |
| ABSTRACT | An example system and method associated with identifying and treating a source of a heart rhythm disorder are disclosed. In accordance therewith, a spatial element associated with a region of the heart is selected. Progressive rotational activations or progressive focal activations are determined in relation to the selected spatial element over a period of time. The selecting and determining are repeated over multiple periods of time. A source parameter of rotation activations or focal activations is determined, wherein the source parameter indicates consistency of successive rotational activations or focal activations in relation to a portion of the region of the heart. The determining of a source parameter is repeated for multiple regions of the heart. Thereafter, representation of the source parameter is displayed for each of the multiple regions of the heart to identify a shape representing the source of the heart rhythm disorder. |
| FILED | Tuesday, May 02, 2017 |
| APPL NO | 15/585091 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/0422 (20130101) A61B 5/02405 (20130101) A61B 2018/00577 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2230/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/365 (20130101) A61N 1/378 (20130101) A61N 1/3622 (20130101) A61N 1/3712 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10435695 | Puckette et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Michael Puckette (Waterford, Connecticut); Max V. Rasmussen (Guilford, Connecticut) |
| ABSTRACT | Polynucleotides encoding fusion proteins comprising interferons and luciferases which have biotherapeutic, diagnostic, and quality control applications in biotechnological, medical, and veterinary fields. |
| FILED | Monday, May 01, 2017 |
| APPL NO | 15/583459 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/21 (20130101) Peptides C07K 14/00 (20130101) C07K 14/56 (20130101) C07K 14/705 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0069 (20130101) C12N 15/00 (20130101) C12N 15/63 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10436612 | Ford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Kevin Ford (Middletown, Connecticut); Eli Warren (Wethersfield, Connecticut); Corey A. Benoit (Uncasville, Connecticut); Edward F Dreger (Burlington, Connecticut); Erik D. Rice (Lebanon, Connecticut); Mark W. Costa (Storrs, Connecticut) |
| ABSTRACT | A capacitance probe monitors the distance between a blade tip and a fan, compressor or turbine case. The capacitance probe may be attached to a liner, and may travel with the liner as it radially expands due to thermal changes. The capacitance probe may include a circuit board sensor with a metallic plate, and one or more capacitors. The metallic plate may be encapsulated within an insulating material. A plurality of soft leads may be in electrical communication with the circuit board sensor, allowing a lower lead weight, reduced size and increased flexibility. The soft leads may also be embedded in the liner. In this way, the capacitance probe can record more accurate distance measurements and promote a gas turbine engine's continued and efficient operation. |
| FILED | Wednesday, October 21, 2015 |
| APPL NO | 14/919225 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 11/20 (20130101) F01D 17/02 (20130101) F01D 21/003 (20130101) F01D 25/24 (20130101) Non-positive-displacement Pumps F04D 29/321 (20130101) F04D 29/325 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/83 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/14 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/2417 (20130101) Original (OR) Class Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 10439538 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Deere and Company (Moline, Illinois) |
| ASSIGNEE(S) | DEERE and COMPANY (Moline, Illinois) |
| INVENTOR(S) | Dan Li (Fargo, North Dakota); Jacob Pence (Dubuque, Iowa); Long Wu (Fargo, North Dakota) |
| ABSTRACT | A motor has a rotor that rotates in response to one or more alternating current input signals. A position sensor is adapted to generate a substantially saw-tooth waveform indicative of a position of the rotor. A primary processing module or data processor is capable of providing position data and speed data for the rotor based on the substantially saw-tooth waveform. A notch filter can reject one or more selected frequency components in the substantially saw-tooth waveform to reduce distortion off the substantially saw-tooth waveform that would otherwise tend to cause inaccuracy in the provided position data and speed data. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/142645 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 11/225 (20160101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 23/18 (20160201) Original (OR) Class H02P 2203/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10436942 | Hoff |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clean Power Research, L.L.C. (Napa, California) |
| ASSIGNEE(S) | Clean Power Research, L.L.C. (Napa, California) |
| INVENTOR(S) | Thomas E. Hoff (Napa, California) |
| ABSTRACT | Statistically representing point-to-point photovoltaic power estimation and area-to-point conversion of satellite pixel irradiance data are described. Accuracy on correlated overhead sky clearness is bounded by evaluating a mean and standard deviation between recorded irradiance measures and the forecast irradiance measures. Sky clearness over the two locations is related with a correlation coefficient by solving an empirically-derived exponential function of the temporal distance. Each forecast clearness index is weighted by the correlation coefficient to form an output set of forecast clearness indexes and the mean and standard deviation are proportioned. Additionally, accuracy on correlated satellite imagery is bounded by converting collective irradiance into point clearness indexes. A mean and standard deviation for the point clearness indexes is evaluated. The mean is set as an area clearness index for the bounded area. For each point, a variance of the point clearness index is determined and the mean and standard deviation are proportioned. |
| FILED | Monday, March 14, 2016 |
| APPL NO | 15/069889 |
| ART UNIT | 2865 — Printing/Measuring and Testing |
| CURRENT CPC | Meteorology G01W 1/10 (20130101) Original (OR) Class G01W 1/12 (20130101) Electric Digital Data Processing G06F 17/18 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 50/04 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/383 (20130101) H02J 2003/007 (20130101) Technologies for Adaptation to Climate Change Y02A 90/15 (20180101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 10/14 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/563 (20130101) Y02E 60/76 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/30 (20151101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/54 (20130101) Y04S 40/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10436583 | Golob et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Richard Golob (Shoreline, Washington); Justin Cleve Hatcher (Seattle, Washington); Jung Soon Jang (Bellevue, Washington); Kimberly Ann Hinson (Seattle, Washington); Jeffrey L. Musgrave (Seattle, Washington) |
| ABSTRACT | A system for detecting a sensor fault of an aerial refueling boom. The system comprises a data collector configured to receive sensor data from a plurality of sensors and determine an aerial refueling boom elevation angle of the aerial refueling boom based on the sensor data, wherein the sensor data comprises at least one of cable length data, a dynamic pressure data or aerial refueling boom position data. The system further comprises a processing unit configured access a database table in a storage unit to determine an estimated aerial refueling boom elevation angle, a comparator configured to compare the estimated aerial refueling boom elevation angle to the determined aerial refueling boom elevation angle, and a fault detector configured to generate a sensor fault signal based on the comparison. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/189384 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 39/00 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 9/02 (20130101) G01C 9/005 (20130101) Original (OR) Class G01C 25/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10440776 | Bishop, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HARRIS CORPORATION (Melbourne, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James William Bishop, Jr. (Colorado Springs, Colorado); Brandon Hinton (Hamilton, Virginia); Leonard Perry Seip (Ashburn, Virginia); William N. Shores (Phoenix, Arizona) |
| ABSTRACT | One example includes a capability gateway that is comprised of a receiver and a transmitter. The receiver receives, from a ground station associated with a satellite system, a standard protocol associated with the ground station and a non-standard alternate protocol that includes alternate service layers inserted into an inter-layer boundary of standard radio layers, the alternate service layers providing end-to-end signaling between the capability gateway and a user equipment. The transmitter transmits the non-standard alternate protocol to the user equipment. |
| FILED | Friday, March 17, 2017 |
| APPL NO | 15/461665 |
| ART UNIT | 2412 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 7/18567 (20130101) Wireless Communication Networks H04W 4/10 (20130101) H04W 40/24 (20130101) H04W 76/12 (20180201) H04W 80/085 (20130101) Original (OR) Class H04W 84/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, October 08, 2019.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20191008.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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