FedInvent™ Patents

Patent Details for Tuesday, October 15, 2019

This page was updated on Monday, March 27, 2023 at 05:55 AM GMT

Department of Defense (DOD)

10441177 — High definition thermal imaging for medical applications

US 10441177	Franzini et al.
FUNDED BY	Department of Defense (DOD) Defense MicroElectronics Activity (DMEA) Department of the Navy (DON)
APPLICANT(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire); Mark B. Lyles (Exeter, Rhode Island)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire); Mark B. Lyles (Exeter, Rhode Island)
INVENTOR(S)	John R. Franzini (Hollis, New Hampshire); Mark B. Lyles (Exeter, Rhode Island); Robert H. Murphy (Lancaster, Massachusetts)
ABSTRACT	An apparatus for high resolution thermal imaging in medical applications has a single channel EMI shielded sensor, remote cable, and laptop controller with real time image processing software. The apparatus provides high resolution, real-time viewable infrared (IR) images with a variable focus distance adjustable from six inches to infinity. The present invention enables crisp, clear imagery of the thermal band for greater awareness of everything within the field of view. Various medical applications which would benefit from high resolution thermal imagery are presented.
FILED	Friday, August 07, 2015
APPL NO	15/109140
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/015 (20130101) Original (OR) Class A61B 5/0077 (20130101) A61B 5/445 (20130101) A61B 5/489 (20130101) A61B 5/725 (20130101) A61B 5/02042 (20130101) A61B 5/4504 (20130101) A61B 5/7203 (20130101) A61B 2562/18 (20130101) A61B 2576/00 (20130101)
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10441185 — Flexible and stretchable electronic systems for epidermal electronics

US 10441185	Rogers et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Neurological Disorders and Stroke (NINDS) Tissue Engineering Resource Center (TERC) National Science Foundation (NSF)
APPLICANT(S)	John A. Rogers (Champaign, Illinois); Dae-Hyeong Kim (Champaign, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	John A. Rogers (Champaign, Illinois); Dae-Hyeong Kim (Champaign, Illinois)
ABSTRACT	Provided herein are skin-mounted biomedical devices and methods of making and using biomedical devices for sensing and actuation applications. For example, flexible and/or stretchable biomedical devices are provided, including electronic devices useful for establishing conformal contact with the skin of a subject. Devices disclosed herein can comprise a plurality of sensing and/or actuating devices provided as part of a skin-mounted flexible or stretchable electronic circuit.
FILED	Friday, June 08, 2012
APPL NO	13/492636
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/076 (20130101) A61B 5/0422 (20130101) A61B 5/0478 (20130101) A61B 5/0492 (20130101) A61B 5/0537 (20130101) A61B 5/1104 (20130101) A61B 5/1107 (20130101) A61B 5/04085 (20130101) Original (OR) Class A61B 5/04284 (20130101) A61B 5/4875 (20130101) A61B 5/6867 (20130101) A61B 2562/02 (20130101) A61B 2562/12 (20130101) A61B 2562/029 (20130101) A61B 2562/046 (20130101) A61B 2562/066 (20130101) A61B 2562/164 (20130101) A61B 2562/0261 (20130101) A61B 2562/0271 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/36 (20130101) A61N 1/0472 (20130101) A61N 1/0587 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/3121 (20130101) H01L 23/3192 (20130101) H01L 27/1218 (20130101) H01L 29/7869 (20130101) H01L 29/78603 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2924/3011 (20130101) H01L 2924/3025 (20130101) H01L 2924/12044 (20130101) H01L 2924/19041 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/147 (20130101) H05K 1/189 (20130101) H05K 1/0283 (20130101) H05K 3/323 (20130101) H05K 2201/09263 (20130101)
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10441225 — Predicting disease recurrence following trimodality therapy in non-small cell lung cancer using computed tomography derived radiomic features and clinico-pathologic features

US 10441225	Madabhushi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Medical Research Acquisition Activity (USAMRAA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Center for Research Resources (NCRR) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Anant Madabhushi (Shaker Heights, Ohio); Mohammadhadi Khorrami (Cleveland, Ohio); Vamsidhar Velcheti (Pepper Pike, Ohio)
ABSTRACT	Embodiments include operations, apparatus, methods and other embodiments that access a baseline CT image of a region of tissue (ROT) demonstrating non-small cell lung cancer (NSCLC), segment a tumoral region represented in the baseline CT image; define a peritumoral region by dilating the tumoral boundary; extract a set of tumoral radiomic features from the tumoral region, a set of peritumoral radiomic features from the peritumoral region, and a set of clinico-pathologic features from the baseline CT image; provide the set of tumoral radiomic features, peritumoral radiomic features, and clinico-pathologic features to a machine learning classifier; receive, from the machine learning classifier, a time-to-recurrence post trimodality therapy (TMT) prediction, based on the set of tumoral radiomic features, peritumoral radiomic features, and clinico-pathologic features; generate a classification of the ROT as an MPR responder or MPR non-responder based, at least in part, on the time-to-recurrence post-TMT prediction; and display the classification.
FILED	Monday, December 31, 2018
APPL NO	16/236675
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/7267 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6284 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0016 (20130101) G06T 7/155 (20170101) G06T 2207/10081 (20130101) G06T 2207/20081 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101)
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10441304 — Surgical tool for tissue sizing and transection

US 10441304	Deister et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	AxoGen Corporation (Alachua, Florida)
ASSIGNEE(S)	AxoGen Corporation (Alachua, Florida)
INVENTOR(S)	Curt Deister (Alachua, Florida); Michael Raymond Orrico (Gainesville, Florida); Gregory Drach (Alachua, Florida)
ABSTRACT	A sizing forceps is provided for fixing a nerve in place, measuring the diameter of the nerve, and providing an efficient way to resect the nerve. A sizing forceps can have an upper and lower jaw with one or more aligned notches that form apertures for holding a nerve. The apertures can have predetermined sizes that can be used to measure the diameter of a nerve. A slicing slot in the upper and lower jaw allows a nerve within an aperture to be severed to obtain a non-frayed end.
FILED	Tuesday, February 07, 2017
APPL NO	15/426460
ART UNIT	3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/282 (20130101) Original (OR) Class A61B 17/1128 (20130101) A61B 2017/320052 (20130101) A61B 2090/061 (20160201) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 3/34 (20130101) G01B 5/08 (20130101)
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10441443 — Multi-modal neural interfacing for prosthetic devices

US 10441443	Harshbarger et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Sea Systems Command (NAVSEA)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Stuart D. Harshbarger (Woodbine, Maryland); James D. Beaty (Sandy Hook, Connecticut); R. Jacob Vogelstein (Bethesda, Maryland); Nitish V. Thakor (Clarksville, Maryland)
ABSTRACT	Methods and systems to interface between physiological devices and a prosthetic device, including to receive a plurality of types of physiological activity signals from a user, decode a user movement intent from each of the plurality of signals types, and fuse the movement intents into a joint decision to control moveable elements of the prosthetic device.
FILED	Thursday, September 22, 2016
APPL NO	15/273039
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0476 (20130101) A61B 5/0496 (20130101) A61B 5/04888 (20130101) A61B 5/7264 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) A61F 2/72 (20130101) Original (OR) Class A61F 2002/5058 (20130101) A61F 2002/5059 (20130101) A61F 2002/5061 (20130101) A61F 2002/5063 (20130101)
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10441610 — Protein delivery from stem cell microcarriers

US 10441610	Boyan et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Barbara Dale Boyan (Richmond, Virginia); Zvi Schwartz (Richmond, Virginia); Christopher S. D. Lee (Atlanta, Georgia); Shirae Kerisha Leslie (Richmond, Virginia); Ramsey C. Kinney (Decatur, Georgia)
ASSIGNEE(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Barbara Dale Boyan (Richmond, Virginia); Zvi Schwartz (Richmond, Virginia); Christopher S. D. Lee (Atlanta, Georgia); Shirae Kerisha Leslie (Richmond, Virginia); Ramsey C. Kinney (Decatur, Georgia)
ABSTRACT	Disclosed are methods and compositions of microbead carriers for delivery of cells and other biologically active substances to diseased or damaged tissue in a subject in need thereof.
FILED	Wednesday, November 23, 2011
APPL NO	13/988929
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/5036 (20130101) A61K 35/28 (20130101) Original (OR) Class A61K 2035/128 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0655 (20130101) C12N 5/0667 (20130101) C12N 2500/25 (20130101) C12N 2500/32 (20130101) C12N 2500/34 (20130101) C12N 2500/38 (20130101) C12N 2501/15 (20130101) C12N 2501/39 (20130101) C12N 2501/155 (20130101) C12N 2533/74 (20130101)
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10441642 — Immunogenic compositions and vaccines for preventing or treating filarial disease

US 10441642	Mitre et al.
FUNDED BY	Department of Defense (DOD) United States Special Operations Command (SOCOM) Uniformed Services University of the Health Sciences (USUHS) Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF) Department of Health and Human Services (HHS)
APPLICANT(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland); The United States Government, as Represented by the Secretary of the Department of Health and Human (Washington, District of Columbia)
ASSIGNEE(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland); The United States Government, as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Edward E. Mitre (Rockville, Maryland); Christopher Morris (North Potomac, Maryland); Sasisekhar Bennuru (Rockville, Maryland); Thomas Nutman (Chevy Chase, Maryland)
ABSTRACT	The present disclosure is directed to an immunogenic composition including: at least one or at least two isolated polypeptides or immunogenic fragments thereof, and optionally a pharmaceutically acceptable carrier, wherein each polypeptide is expressed on a luminal surface of an intestine of a filarial worm, wherein each polypeptide is expressed at a level at least two-fold higher in the intestine in comparison to the level of expression of each polypeptide in a reproductive tract or a body wall of the filarial worm, wherein each isolated polypeptide has at least one transmembrane domain, and wherein each polypeptide is a non-mitochondrial polypeptide. Also provided herein is a method for preventing or treating a filarial disease.
FILED	Thursday, March 17, 2016
APPL NO	15/558336
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/1767 (20130101) A61K 39/0003 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/55566 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/10 (20180101) Peptides C07K 14/4354 (20130101)
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10441646 — Infectious plasmodium sporozoites grown in vitro

US 10441646	Eappen et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Congressionally Directed Medical Research Programs (CDMRP) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	SANARIA INC. (Rockville, Maryland)
ASSIGNEE(S)	Sanaria Inc. (Rockville, Maryland)
INVENTOR(S)	Abraham G. Eappen (Ellicott City, Maryland); Stephen L. Hoffman (Gaithersburg, Maryland)
ABSTRACT	The application is directed to in vitro-reared Plasmodium sporozoites of human host range wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same. Provided herein are in vitro-reared infectious Plasmodium sporozoites (SPZ) of human host range, particularly P. falciparum, P. vivax, P. ovale, P. malariae, and P. knowlesi, wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same.
FILED	Friday, December 29, 2017
APPL NO	15/858574
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/015 (20130101) Original (OR) Class A61K 2039/52 (20130101) A61K 2039/522 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/10 (20130101) Technologies for Adaptation to Climate Change Y02A 50/412 (20180101)
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10441950 — Method for transferring a target between locations

US 10441950	Beebe et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	David J. Beebe (Monona, Wisconsin); Ben P. Casavant (Madison, Wisconsin); David J. Guckenberger (Oconomowoc, Wisconsin); Scott M. Berry (Madison, Wisconsin)
ABSTRACT	A device and method are proved for transferring a target from a first location to a second location. The target is bound to solid phase substrate to form a target bound solid phase substrate. The device includes transfer surface for receiving the target bound solid phase substrate thereon for transfer. The transfer surface movable between a first position wherein the transfer surface is aligned with the first location and spaced therefrom by a distance and a second position wherein the transfer surface is aligned with the second location. An alignment structure aligns the transfer surface with respect to the second location, with the transfer surface in the second position. A force is movable between an attraction position wherein the target bound solid phase substrate are drawn toward the transfer surface and a discharge position wherein the target bound solid phase substrate are free of the force.
FILED	Tuesday, July 17, 2018
APPL NO	16/037153
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) Original (OR) Class B01L 3/563 (20130101) B01L 3/5088 (20130101) B01L 3/50825 (20130101) B01L 2200/025 (20130101) B01L 2200/0657 (20130101) B01L 2200/0668 (20130101) B01L 2300/042 (20130101) B01L 2400/021 (20130101) B01L 2400/043 (20130101)
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10441962 — Cold spray device and system

US 10441962	Widener et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	South Dakota Board of Regents (Pierre, South Dakota)
ASSIGNEE(S)	SOUTH DAKOTA BOARD OF REGENTS (Pierre, South Dakota); GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia)
INVENTOR(S)	Christian Widener (Rapid City, South Dakota); Victor Champagne (Rapid City, South Dakota); Matthew Trexler (Rapid City, South Dakota); Dennis Helfritch (Rapid City, South Dakota); Rob Hrabe (Rapid City, South Dakota)
ABSTRACT	Cold spray devices and systems are disclosed. They include a flowpath having an inlet adapted for receiving communication with two or more inputs and an outlet adapted to discharge the two or more inputs. A discharge nozzle may be included in the flowpath of the outlet and a confluence may be included in the flowpath at the inlet for combining the two or more inputs. A nozzle body houses the discharge nozzle separate and downstream from the confluence of the two inputs.
FILED	Tuesday, October 29, 2013
APPL NO	14/066346
ART UNIT	3752 — Fluid Handling and Dispensing
CURRENT CPC	Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/1486 (20130101) B05B 7/1613 (20130101) B05B 7/1693 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 24/04 (20130101)
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10442114 — Compartmentalized resin pellets

US 10442114	Ferrari
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Aberdeen Proving Ground (APG)
APPLICANT(S)	M and G USA Corporation (Apple Grove, West Virginia)
ASSIGNEE(S)	APG Polytech, LLC (Wilmington, Delaware)
INVENTOR(S)	Gianluca Ferrari (Portogruaro, Italy)
ABSTRACT	Disclosed herein is a resin pellet and a process to make said resin pellet. The resin pellet comprises a major polyester comprising a catalytic titanium compound, and a minor polyester comprising a phosphorus compound. The major polyester is present in a first compartmentalized zone of the resin pellet and the minor polyester is present in a second compartmentalized zone of the resin pellet.
FILED	Friday, June 03, 2016
APPL NO	15/578878
ART UNIT	1768 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 9/12 (20130101) Original (OR) Class B29B 9/065 (20130101) B29B 2009/163 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/80 (20130101) C08G 63/85 (20130101) C08G 63/183 (20130101) C08G 63/916 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/51 (20130101) Compositions of Macromolecular Compounds C08L 67/02 (20130101) C08L 2207/53 (20130101) C08L 2310/00 (20130101)
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10442532 — Composite swashplate guide for rotorcraft control systems

US 10442532	Orbon et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Aviation and Missile Center (CCDC AVMC)
APPLICANT(S)	Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S)	SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S)	James Orbon (New Haven, Connecticut); Dean Nguyen (Greenwich, Connecticut); Kevin Laitenberger (Beacon Falls, Connecticut); Steven M. Capelle (Derby, Connecticut)
ABSTRACT	A swashplate guide for use with a spherical bearing and which connects with an adjacent component includes a hollow cylindrical tube formed from a composite material. An exterior surface of the hollow cylindrical tube provides an engagement surface with the spherical bearing. A flange arranged at an end of the hollow cylindrical tube provides an interface with the adjacent component.
FILED	Monday, September 18, 2017
APPL NO	15/707631
ART UNIT	3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Aeroplanes; Helicopters B64C 27/605 (20130101) Original (OR) Class B64C 2027/7238 (20130101) B64C 2027/7255 (20130101)
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10443032 — Device and method for isolation of corneal endothelial cells

US 10443032	Haggins, Jr. et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Fort Detrick, Maryland)
ASSIGNEE(S)	The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland)
INVENTOR(S)	Robert Haggins, Jr. (Belcamp, Maryland); Erik Eaton, Jr. (Havre de Grace, Maryland); Zachary Murray (Jarrettsville, Maryland); Timothy Varney (Baltimore, Maryland)
ABSTRACT	An apparatus (8) for isolating corneal endothelial cells (34) (CECs) includes a base portion (10) having an interior recessed opening (14) with a bottom surface (16). A convex projection (18) is centrally located on the bottom surface (16) and is configured to receive an inverted cornea (32). A top portion (12) is configured to mate with the base portion (10). The top portion (12) includes a fluid chamber (24) with a lower surface (20). The lower surface (20) has an opening (22) therein in which the convex projection (18) projects when the top portion (12) is mated with the base portion (10).
FILED	Wednesday, April 19, 2017
APPL NO	16/060078
ART UNIT	1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 23/02 (20130101) C12M 25/00 (20130101) C12M 29/06 (20130101) C12M 29/14 (20130101) C12M 29/26 (20130101) C12M 41/48 (20130101) C12M 47/04 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101)
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10443050 — Sample processing methods

US 10443050	Chen et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Roche Molecular Systems, Inc. (Pleasanton, California)
ASSIGNEE(S)	Roche Molecular Systems, Inc. (Pleasanton, California)
INVENTOR(S)	Shuqi Chen (Framingham, Massachusetts); Lingjun Chen (Framingham, Massachusetts)
ABSTRACT	A method of processing a sample may include introducing a sample into a vessel, the vessel having proximal and distal ends, the sample being introduced into the proximal end of the vessel; incubating the sample in the vessel with a substance capable of specific binding to a preselected component of the sample; propelling components of the incubated sample, other than the preselected component, toward the proximal end of the vessel by clamping the vessel distal to the incubated sample and compressing the vessel where the incubated sample is contained; propelling the preselected component toward a distal segment of the vessel by clamping the vessel proximal to the preselected component and compressing the vessel where the preselected component is contained; and mixing the preselected component with a reagent in the distal segment of the vessel.
FILED	Thursday, June 15, 2017
APPL NO	15/624535
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/505 (20130101) B01L 2200/10 (20130101) B01L 2200/0621 (20130101) B01L 2300/10 (20130101) B01L 2300/042 (20130101) B01L 2300/046 (20130101) B01L 2300/047 (20130101) B01L 2300/069 (20130101) B01L 2300/087 (20130101) B01L 2300/0681 (20130101) B01L 2400/0481 (20130101) B01L 2400/0677 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1003 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 33/543 (20130101) Technologies for Adaptation to Climate Change Y02A 50/52 (20180101) Y02A 50/53 (20180101) Y02A 50/58 (20180101) Y02A 50/60 (20180101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 435/81 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/25 (20150115)
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10443073 — Sin Nombre virus full-length M segment-based DNA vaccines

US 10443073	Hooper
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland)
ASSIGNEE(S)	The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland)
INVENTOR(S)	Jay Hooper (New Market, Maryland)
ABSTRACT	The invention contemplates a new synthetic, codon-optimized Sin Nombre virus (SNV) full-length M gene open reading frame (ORF) that encodes a unique consensus amino acid sequence. The SNV ORF was cloned into a plasmid to form the first stable recombinant SNV full-length M gene that elicits neutralizing antibodies. The gene can be engineered into a vaccine system, and is useful to protect mammals against infection with Sin Nombre virus.
FILED	Friday, March 25, 2016
APPL NO	15/081218
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/575 (20130101) Peptides C07K 14/005 (20130101) C07K 16/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2760/12111 (20130101) C12N 2760/12121 (20130101) C12N 2760/12122 (20130101) C12N 2760/12134 (20130101) C12N 2760/12143 (20130101) C12N 2760/12151 (20130101)
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10443260 — Modular anti-ballistic, blast and forced entry resistant shelter system

US 10443260	Roberts et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	United States of America as Represented by The Secretary of The Army (Alexandria, Virginia)
ASSIGNEE(S)	United States of America as Represented by The Secretary of The Army (Alexandria, Virginia)
INVENTOR(S)	Justin M Roberts (Florence, Mississippi); John M Hoemann (Vicksburg, Mississippi); Craig R. Ackerman (Gainesville, Virginia)
ABSTRACT	The modular anti-ballistic shelter system includes two end units and, optionally, additional middle units for a wider structure. End and middle units may also stack atop each other for multi-story structures. Each unit is configured to comply with both ISO standards for size and weight, and with the U.S. Department of State Certification Standard for Forced Entry and Ballistic Resistance of Structural Systems. Each exterior wall of each end unit and each middle unit is reinforced with wall studs that penetrate the unit's structural framework of beams and frames. Even though these wall studs are welded into place, penetration of the wall studs into the beams and frames ensures acceptable blast, ballistic, and forced entry resistance even if the welds are flawed.
FILED	Thursday, March 16, 2017
APPL NO	15/461333
ART UNIT	3633 — Static Structures, Supports and Furniture
CURRENT CPC	Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 6/00 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/1912 (20130101) E04B 1/2403 (20130101) E04B 2/58 (20130101) E04B 5/10 (20130101) E04B 7/022 (20130101) E04B 2001/199 (20130101) E04B 2001/1972 (20130101) E04B 2001/2427 (20130101) E04B 2001/2448 (20130101) E04B 2001/2463 (20130101) E04B 2001/2466 (20130101) E04B 2001/2481 (20130101) E04B 2001/2484 (20130101) E04B 2103/06 (20130101) Structural Elements; Building Materials E04C 3/06 (20130101) E04C 3/32 (20130101) E04C 2003/0465 (20130101) E04C 2003/0473 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 9/10 (20130101) Original (OR) Class E04H 2001/1283 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 1/02 (20130101) E06B 1/56 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 7/04 (20130101)
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10443415 — Flowpath assembly for a gas turbine engine

US 10443415	Corsmeier et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S)	Donald Michael Corsmeier (West Chester, Ohio); Bryan Harris Farrar (Cincinnati, Ohio)
ABSTRACT	A flowpath apparatus for a gas turbine engine includes: a plurality of ducts arranged in an array, each duct including a peripheral wall structure having a closed perimeter that defines a flow channel from an upstream end to a downstream end thereof; and a support structure positioning a the plurality of ducts in an array configuration.
FILED	Wednesday, March 30, 2016
APPL NO	15/085552
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/04 (20130101) Original (OR) Class F01D 9/047 (20130101) F01D 25/005 (20130101) F01D 25/145 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/128 (20130101) F05D 2300/6033 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101)
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10443425 — Blade outer air seal fin cooling assembly and method

US 10443425	Romanov et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Dmitriy A. Romanov (Wells, Maine); Jose R. Paulino (Saco, Maine); Ken F. Blaney (Middleton, New Hampshire)
ABSTRACT	A blade outer air seal according to an exemplary aspect of the present disclosure includes, among other things, a body to be distributed circumferentially about a blade array. The body has a plurality of grooves, which can, for example, improve the aerodynamic efficiency of a turbine. A fin is between a first groove and a second groove of the plurality of grooves. The fin extends radially from the body and terminates at a radially inner fin face that provides one or more cooling outlets.
FILED	Thursday, February 12, 2015
APPL NO	15/118521
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Foundry Moulding B22C 9/10 (20130101) B22C 9/24 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/08 (20130101) Original (OR) Class F01D 11/24 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/211 (20130101) F05D 2240/11 (20130101) F05D 2260/204 (20130101) F05D 2260/22141 (20130101) F05D 2300/13 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101)
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10443499 — Enhanced heat sink availability on gas turbine engines through the use of coolers

US 10443499	Snyder
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana)
ASSIGNEE(S)	Rolls Royce North American Technologies, Inc. (Indianapolis, Indiana)
INVENTOR(S)	Douglas J. Snyder (Carmel, Indiana)
ABSTRACT	A cooling assembly for a gas turbine engine including a heat source at a first temperature, a heat sink at a second temperature, and a heat pump coupled to the first heat source and the first heat sink. The heat pump is configured to convey a quantity of heat from the heat source through the heat pump and to the heat sink.
FILED	Thursday, May 07, 2015
APPL NO	14/706062
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/12 (20130101) F02C 7/14 (20130101) F02C 7/16 (20130101) Original (OR) Class F02C 7/224 (20130101) Jet-propulsion Plants F02K 3/115 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/213 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/30 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20163 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101)
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10443625 — Airfoil singlets

US 10443625	Langenbrunner et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Leslie Louis Langenbrunner (Cincinnati, Ohio); Ian Francis Prentice (Cincinnati, Ohio); Rosa Lee Nemec (Cincinnati, Ohio); Adam Max Aresty (West Chester, Ohio); Ming Xie (Beavercreek, Ohio); Andrew McGee (Oxford, Ohio)
ABSTRACT	Composite airfoil singlet, includes airfoil extending from base to tip of airfoil, integrally formed with no more than one outer platform at tip and/or no more than one inner platform at base. Parallel composite plies or woven fibers extend through airfoil and through outer and/or inner platforms. Outer and/or inner curved sections extend between outer and/or inner platforms and airfoil respectively. Assembly includes circular row of the composite airfoil singlets depending radially inwardly from and mounted to an outer shroud or casing. Outer and/or inner fasteners may secure outer and inner platforms to outer shroud or casing and an inner shroud respectively and include shanks extending substantially perpendicularly from outer and inner fastening plates though platform holes in outer and inner platforms and through outer and inner holes in outer shroud or casing and inner shroud respectively. Nuts are screwed on threaded ends of shanks.
FILED	Wednesday, September 21, 2016
APPL NO	15/271312
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/042 (20130101) Non-positive-displacement Pumps F04D 29/023 (20130101) F04D 29/542 (20130101) F04D 29/644 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/80 (20130101) F05D 2260/31 (20130101) F05D 2300/6033 (20130101) F05D 2300/6034 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101)
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10443663 — Clutch coupled to gas turbine engine and method for cooling

US 10443663	Bouton et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	Rolls-Royce Corporation (Indianapolis, Indiana)
ASSIGNEE(S)	Rolls-Royce Corporation (Indianapolis, Indiana)
INVENTOR(S)	Matthew T. Bouton (Indianapolis, Indiana); Doug M. Schwerin (Zionsville, Indiana)
ABSTRACT	A gas turbine engine clutch includes a dry clutch assembly, forward and aft working areas, and a shaft. The dry clutch assembly is operative to receive power from a gas turbine engine. The dry clutch assembly is configured to selectively engage the gas turbine engine with a driven source, and has an axial opening extending therethrough. The forward and aft working areas are disposed at axially opposite ends of the dry clutch assembly. The shaft extends axially through the axial opening of the dry clutch assembly, and defines an axial fluid flow passage therethrough in liquid fluid communication with the forward and aft working areas.
FILED	Tuesday, September 20, 2016
APPL NO	15/270486
ART UNIT	3655 — Material and Article Handling
CURRENT CPC	Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/16 (20130101) F02C 7/36 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/61 (20130101) F05D 2260/20 (20130101) F05D 2260/4023 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 13/52 (20130101) F16D 13/72 (20130101) Original (OR) Class Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101)
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10443732 — Oil slinger with convective cooling of radial surface

US 10443732	Clark et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Thomas E. Clark (Sanford, Maine); Eric Charles Mundell (South Berwick, Maine); Gary L. Grogg (South Berwick, Maine)
ABSTRACT	Oil slinger systems include a seal runner comprising an annular radial member having a radius (R) and an outer axially extending member having an axial length (L) such that a ratio (L/R) is between 0.8 and 1.4, the annular radial member disposed at a first angle with respect to the outer axially extending member, a heat shield in mechanical communication with the seal runner, and a volume bounded by an outer face of the annular radial member and an inner face of the heat shield. Methods of radial convective cooling include pumping a cooling liquid through the oil slinger system and convectively cooling the oil slinger.
FILED	Monday, March 21, 2016
APPL NO	15/075955
ART UNIT	3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/12 (20130101) F01D 25/18 (20130101) F01D 25/183 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2230/60 (20130101) F05D 2240/55 (20130101) F05D 2260/20 (20130101) Pistons; Cylinders; Sealings F16J 15/168 (20130101) Original (OR) Class Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101)
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10443992 — Non-pyrotechnic diversionary device

US 10443992	Cayer
FUNDED BY	Department of Defense (DOD) Assistant Secretary of Defense for Special Operations/Low-Intensity Conflict (ASD SOLIC) Technical Support Working Group (TSWG)
APPLICANT(S)	Applied Research Associates, Inc. (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S)	Richard Cayer (Littleton, Colorado)
ABSTRACT	The disclosed technology regards a reusable, non-pyrotechnic diversionary device having a housing assembly which receives and supports a pressure manifold, activation assembly, and a lighting assembly. The housing assembly includes a vessel, a main chassis, and a transparent lens. Positioned within the main chassis is a pressure manifold which supports a compressed gas source. A puncture pin is provided in the activation assembly, and aligned with the compressed gas source to facilitate puncture of the source. The disclosed technology further regards a reusable, non-pyrotechnic diversionary assembly having a housing assembly and a reloading tool. The reloading tool has an externally threaded inner body with an aperture at its distal end sized to receive the puncture pin, and an outer body sized and internally threaded to rotatably receive a portion of the inner body in its shaft, allowing the inner body to traverse through and from the shaft at its distal end. A threaded interface is provided on the outer body of the reloading tool to align with the first support structure of the pressure manifold. The inner body rotationally translates within the outer body to position the distal end of the inner body relative to the puncture pin and allow it to translate the puncture pin from an active position to a secured position.
FILED	Wednesday, March 22, 2017
APPL NO	15/466492
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 4/04 (20130101) F42B 12/42 (20130101) Original (OR) Class F42B 27/00 (20130101) F42B 33/02 (20130101)
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10443993 — Spin discarding multiple projectile sabot

US 10443993	Chaplin et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	U.S. Government as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Raymond Chaplin (Hopatcong, New Jersey); Christopher C. Parisi (Lake Hopatcong, New Jersey)
ABSTRACT	An ammunition round for simultaneously launching multiple penetrators enclosed with a single composite sabot, without any nesting or physical contact between the penetrators. The composite sabot has petals which are engraved by the tube's rifling during launch to rotate the petals, without presence of a separate rotating band element. The petals are separated from the penetrator elements upon exit from the gun tube solely by centrifugal forces acting on the petals.
FILED	Thursday, November 29, 2018
APPL NO	16/203706
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/06 (20130101) F42B 14/064 (20130101) Original (OR) Class F42B 14/065 (20130101)
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10444187 — System and method for electrical characterization of electrical materials

US 10444187	Grayson et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Matthew Grayson (Evanston, Illinois); Jiajun Luo (Evanston, Illinois)
ABSTRACT	Systems and methods can provide a fast and accurate way to measure conductivity and Hall effect, such that transient conductivities, transient carrier densities or transient mobilities can be measured on millisecond time scales, for example. The systems and methods can also reduce the minimum magnetic field needed to extract carrier density or mobility of a given sample, and reduce the minimum mobility that can be measured with a given magnetic field.
FILED	Wednesday, August 30, 2017
APPL NO	15/690624
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/72 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 15/202 (20130101) G01R 19/08 (20130101) G01R 31/2648 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/11 (20130101) H05K 2201/032 (20130101)
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10444223 — Integrated organ-on-chip systems and applications of the same

US 10444223	Wikswo et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Defense Threat Reduction Agency (DTRA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) National Cancer Institute (NCI) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	John P. Wikswo (Brentwood, Tennessee); David E. Cliffel (Nashville, Tennessee); Dmitry A. Markov (Nashville, Tennessee); John A. McLean (Nashville, Tennessee); Lisa Joy McCawley (Nashville, Tennessee); Phillip C. Samson (Nashville, Tennessee); Ronald S. Reiserer (Nashville, Tennessee); Frank Emmanuel Block (Nashville, Tennessee); Jennifer Robin McKenzie (Nashville, Tennessee)
ABSTRACT	A microclinical analyzer usable for analysis of one or more bio-objects, each bio-object including an organ or a group of cells includes a fluidic network having a plurality of fluidic switches, a plurality of fluidic paths in fluid communication with the plurality of fluidic switches, and one or more on-chip pumps coupled to corresponding fluidic paths; a sensor array coupled to the fluidic network; and a microcontroller for individually controlling the plurality of fluidic switches and the one or more on-chip pumps of the fluidic network as so to operably and selectively deliver an effluent of at least one bio-object to the sensor array for detecting properties of the effluent, or to a predetermined outlet destination.
FILED	Monday, July 30, 2018
APPL NO	16/049025
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0247 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502715 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0877 (20130101) B01L 2400/0481 (20130101) B01L 2400/0487 (20130101) B01L 2400/0622 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) Original (OR) Class G01N 35/1095 (20130101)
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10444254 — Virtual tachometers based on time series filtering

US 10444254	Winslow et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S)	SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S)	Christopher L. Winslow (Trumbull, Connecticut); Biqing Wu (Vancouver, Washington); Mark W. Davis (Southbury, Connecticut)
ABSTRACT	A system and method for receiving a plurality of first inputs from a transducer, where the plurality of first inputs correspond to vibrations of a rotational machine, and filtering the plurality of first inputs to derive a frequency of interest. The system and method then generates a sinusoidal signal at the frequency of interest and a pulse train of one or multiple pulses per revolution at the frequency of interest from the sinusoidal signal. The system and method further identifies a first pulse at a zero crossing within the pulse train and counts zero crossings to define blocks of data for use in time synchronous averaging calculations.
FILED	Monday, October 19, 2015
APPL NO	15/534887
ART UNIT	2864 — Printing/Measuring and Testing
CURRENT CPC	Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 1/006 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/48 (20130101) G01P 3/4807 (20130101) Original (OR) Class G01P 15/00 (20130101)
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10444328 — High-power laser (HPL) system with integral track illuminator

US 10444328	Saunders
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Government of the United States, as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico)
ASSIGNEE(S)	United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Patrick D. Saunders (Tijeras, New Mexico)
ABSTRACT	A high-power laser (HPL) system and method for targeting an object and imaging/tracking the object with an integral track illuminator. The system includes a HPL optically coupled to an aperture sharing element (ASE) and configured to project high-power light at the object, and to switch off for prescribed time intervals to illuminate and track the object. At least one camera is optically coupled to and disposed with respect to the ASE to track the illuminated object over a shared optical path with the HPL when the HPL is switched off for a prescribed time interval.
FILED	Tuesday, July 24, 2018
APPL NO	16/044133
ART UNIT	2877 — Optics
CURRENT CPC	Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 13/0062 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/481 (20130101) G01S 7/4804 (20130101) Original (OR) Class G01S 17/026 (20130101) G01S 17/66 (20130101) G01S 17/895 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0071 (20130101)
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10444330 — LADAR receiver with enhanced signal to noise ratio and method

US 10444330	Stann et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Barry Lee Stann (Edgewater, Maryland); Mark Michael Giza (Kensington, Maryland)
ABSTRACT	A laser receiver comprising a sensor; a first amplifier operatively connected to the sensor comprising a first gate, a first source and a first drain; a first subcircuit operatively connected between the first drain and the first gate comprising a first resistor, a first inductor and a decoupling capacitor configured to allow the first amplifier bias to be established by the at least one first biasing resistor; the impedance of the first gate being sufficient such that only a small proportion of the current from the sensor passes into the first gate; an inductor connecting the first gate to the at least one biasing resistor with high impedance at the receiver operating frequency; a second amplifier comprising a second gate operatively connected to the first drain; and an output configured to be operatively connected to a processing unit and a display unit configured to displaying output and method thereof.
FILED	Tuesday, November 01, 2016
APPL NO	15/340307
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/489 (20130101) G01S 7/4816 (20130101) Original (OR) Class G01S 7/4817 (20130101) G01S 7/4818 (20130101) G01S 7/4863 (20130101) G01S 17/10 (20130101) G01S 17/42 (20130101) G01S 17/89 (20130101)
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10444431 — Reticulated resonator, process for making and use of same

US 10444431	Simmonds et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Physics (PHY)
APPLICANT(S)	NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland); Cindy Regal (Boulder, Colorado); Pen-Li Yu (West Lafayette, Indiana); Yeghishe Tsaturyan (Copenhagen, Denmark); Thomas P. Purdy (Boulder, Colorado); Nir Shlomo Kampel (Boulder, Colorado)
ASSIGNEE(S)	NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland)
INVENTOR(S)	Raymond W. Simmonds (Boulder, Colorado); Katarina Cicak (Boulder, Colorado); Cindy A. Regal (Boulder, Colorado); Pen-Li Yu (West Lafayette, Indiana); Yeghishe Tsaturyan (Copenhagen, Denmark); Thomas P. Purdy (Gaithersburg, Maryland); Nir S. Kampel (Boulder, Colorado)
ABSTRACT	A reticulated resonator includes: a reticulated substrate that includes: a substrate frame; and a phononic structure in mechanical communication with the substrate frame and including a plurality of unit members arranged in a two-dimensional array; and a membrane disposed on the reticulated substrate. A process for producing a membrane frequency includes: providing a reticulated resonator including: a substrate frame; a phononic structure including: a first link connected to the substrate frame; a plurality of unit members arranged in a two-dimensional array and connected to the first link and in mechanical communication with the substrate frame through the first link; and a second link connected to the unit members; a membrane frame connected to the second link and in mechanical communication with the unit members through the second link; and a membrane disposed on the membrane and in mechanical communication with the substrate frame through the membrane frame and the unit members; subjecting the membrane to an excitation frequency; receiving, by the membrane, the excitation frequency; and producing, by the membrane, a membrane mode including a membrane frequency in response to receiving the excitation frequency.
FILED	Thursday, January 14, 2016
APPL NO	14/995853
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Optical Elements, Systems, or Apparatus G02B 6/1225 (20130101) Original (OR) Class
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10444595 — Technique for dynamically controlling the incoupler of a beam-steering device

US 10444595	Myers et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jason D. Myers (Alexandria, Virginia); Jesse A. Frantz (Washington, District of Columbia); Christopher M. Spillmann (Annandale, Virginia); Robel Y. Bekele (Washington, District of Columbia); Henry G. Gotjen (Washington, District of Columbia); Jawad Naciri (Arlington, Virginia); Jakub Kolacz (Washington, District of Columbia); L. Brandon Shaw (Woodbridge, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia)
ABSTRACT	An optical system has a beam-steering device having a planar waveguide region between a tapered incoupler and a tapered outcoupler that respectively define opposing incoupler and outcoupler facets of the BS device. Each region has a substrate, a subcladding layer over the substrate, a core layer over the subcladding, and a top cladding layer over the core. Within the incoupler, at least one of the subcladding and the top cladding has a material having a refractive index that varies with an applied field (e.g., an electric field) applied at the incoupler. The optical system also has a field-applying device that applies the applied field at the incoupler, an output detector that generates a feedback signal based on detected outgoing light output from the outcoupler, and a controller that controls the field-applying device based on the feedback signal to alter the light output from the outcoupler.
FILED	Thursday, January 03, 2019
APPL NO	16/238642
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/305 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0118 (20130101) G02F 1/292 (20130101) Original (OR) Class G02F 1/295 (20130101) G02F 1/1326 (20130101) G02F 2001/0113 (20130101) G02F 2001/291 (20130101) G02F 2203/24 (20130101)
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10445098 — Processors and methods for privileged configuration in a spatial array

US 10445098	Fleming et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	INTEL CORPORATION (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Kermin E. Fleming (Hudson, Massachusetts); Simon C. Steely (Hudson, New Hampshire); Kent D. Glossop (Merrimack, New Hampshire)
ABSTRACT	Methods and apparatuses relating to privileged configuration in spatial arrays are described. In one embodiment, a processor includes processing elements; an interconnect network between the processing elements; and a configuration controller coupled to a first subset and a second, different subset of the plurality of processing elements, the first subset having an output coupled to an input of the second, different subset, wherein the configuration controller is to configure the interconnect network between the first subset and the second, different subset of the plurality of processing elements to not allow communication on the interconnect network between the first subset and the second, different subset when a privilege bit is set to a first value and to allow communication on the interconnect network between the first subset and the second, different subset of the plurality of processing elements when the privilege bit is set to a second value.
FILED	Saturday, September 30, 2017
APPL NO	15/721809
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 9/544 (20130101) G06F 9/3017 (20130101) Original (OR) Class G06F 9/3895 (20130101) G06F 9/5016 (20130101)
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10445234 — Processors, methods, and systems for a configurable spatial accelerator with transactional and replay features

US 10445234	Fleming et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Kermin Fleming (Hudson, Massachusetts); Kent D. Glossop (Merrimack, New Hampshire); Simon C. Steely, Jr. (Hudson, New Hampshire); Samantika S. Sury (Westford, Massachusetts)
ABSTRACT	Systems, methods, and apparatuses relating to a configurable spatial accelerator are described. In an embodiment, a processor includes a plurality of processing elements; and an interconnect network between the plurality of processing elements to receive an input of a dataflow graph comprising a plurality of nodes, wherein the dataflow graph is to be overlaid into the interconnect network and the plurality of processing elements with each node represented as a dataflow operator in the plurality of processing elements, and the plurality of processing elements are to perform an atomic operation when an incoming operand set arrives at the plurality of processing elements.
FILED	Saturday, July 01, 2017
APPL NO	15/640533
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 12/0802 (20130101) Original (OR) Class G06F 15/7867 (20130101) G06F 15/8015 (20130101) G06F 17/505 (20130101) Static Stores G11C 7/1012 (20130101) G11C 8/12 (20130101) G11C 2207/2245 (20130101) Pulse Technique H03K 19/1776 (20130101) H03K 19/1778 (20130101) H03K 19/17736 (20130101) H03K 19/17756 (20130101) H03K 19/17764 (20130101) H03K 19/17776 (20130101)
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10445250 — Apparatus, methods, and systems with a configurable spatial accelerator

US 10445250	Fleming et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Kermin E. Fleming (Hudson, Massachusetts); Kent D. Glossop (Merrimack, New Hampshire); Simon C. Steely (Hudson, New Hampshire)
ABSTRACT	Systems, methods, and apparatuses relating to a configurable spatial accelerator are described. In one embodiment, a processor includes a core with a decoder to decode an instruction into a decoded instruction and an execution unit to execute the decoded instruction to perform a first operation; a plurality of processing elements; and an interconnect network between the plurality of processing elements to receive an input of a dataflow graph comprising a plurality of nodes, wherein the dataflow graph is to be overlaid into the interconnect network and the plurality of processing elements with each node represented as a dataflow operator in the plurality of processing elements, and the plurality of processing elements are to perform a second operation by a respective, incoming operand set arriving at each of the dataflow operators of the plurality of processing elements.
FILED	Saturday, December 30, 2017
APPL NO	15/859454
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 12/1054 (20130101) Original (OR) Class G06F 2212/608 (20130101) G06F 2212/683 (20130101)
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10445356 — Method and system for analyzing entities

US 10445356	Mugan et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	PULSELIGHT HOLDINGS, INC. (Austin, Texas)
ASSIGNEE(S)	Pulselight Holdings, Inc. (Austin, Texas)
INVENTOR(S)	Jonathan William Mugan (Buda, Texas); Laura Hitt (Austin, Texas); Jimmie Goode (Austin, Texas); Russ Gregory (Austin, Texas); Yuan Qu (Austin, Texas)
ABSTRACT	A recurrent neural network (RNN) method implemented on a computer system is used to produce summaries of unstructured text generated by multiple networks of individuals interacting over time by encoding the unstructured text into intermediate representations and decoding the intermediate representations into summaries of each network. Parameter data for the RNN is obtained by using multiple different versions of the same source texts to train the computer system. The method and computer system can be used to identify which of the networks match a query by determining which network generates the query with low or lowest cost.
FILED	Friday, June 23, 2017
APPL NO	15/632180
ART UNIT	2657 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC	Electric Digital Data Processing G06F 16/334 (20190101) G06F 16/345 (20190101) Original (OR) Class G06F 17/289 (20130101) G06F 17/2785 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101)
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10445405 — Method of performing variance calculations in real-time for in-situ instant variance measurements for low power applications

US 10445405	Sandquist
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S)	Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S)	David Sandquist (Saint Paul, Minnesota)
ABSTRACT	A system for performing real-time variance analysis of data measurements comprises a data source, and a data processing unit in operative communication with the data source. The data processing unit is configured to receive data measurement values output from the data source and comprises a processer, and a memory device that includes instructions executable by the processor for a real-time algorithm that performs variance calculations for the data measurement values. The real-time algorithm performs a process comprising: initializing a data array for tracking a variance of individual data measurement values received from the data source; receiving a data measurement value from the data source; determining the number of averaging times to be recalculated; and repeating the process when the next data measurement value is received from the data source. The data processing unit is configured to output real-time variance measurements based on the variance calculations for the data measurement values.
FILED	Wednesday, January 25, 2017
APPL NO	15/414967
ART UNIT	2857 — Printing/Measuring and Testing
CURRENT CPC	Electric Digital Data Processing G06F 17/18 (20130101) Original (OR) Class
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10445442 — System and method for game theory-based design of robotic systems

US 10445442	English et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Contracting Command (ACC)
APPLICANT(S)	ENERGID TECHNOLOGIES CORPORATION (Cambridge, Massachusetts)
ASSIGNEE(S)	Energid Technologies Corporation (Cambridge, Massachusetts)
INVENTOR(S)	James D. English (Alva, Florida); Ryan S. Penning (Madison, Wisconsin); Douglas E. Barker (Somerville, Massachusetts); Paul Muench (Livonia, Michigan); Brett L. Limone (Malden, Massachusetts)
ABSTRACT	A method, computer program product, and computer system for configuring a stochastic simulation scenario, wherein the stochastic simulation scenario may include one or more variables, wherein at least a portion of the one or more variables may include agent behavior, and wherein the stochastic simulation scenario may be randomized and digital. The stochastic simulation scenario may be executed to generate one or more results of the stochastic simulation scenario. At least a portion of the one or more variables may be optimized using one or more optimization metrics on the one or more results of the stochastic simulation scenario, wherein at least the portion of the one or more variables may be modified based on game theory.
FILED	Thursday, September 01, 2016
APPL NO	15/254383
ART UNIT	2194 — Interprocess Communication and Software Development
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 9/1671 (20130101) Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class G06F 2217/10 (20130101)
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10445451 — Processors, methods, and systems for a configurable spatial accelerator with performance, correctness, and power reduction features

US 10445451	Fleming et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Kermin Fleming (Hudson, Massachusetts); Kent D. Glossop (Merrimack, New Hampshire); Simon C. Steely, Jr. (Hudson, New Hampshire); Ping Tak Peter Tang (Edison, New Jersey)
ABSTRACT	Systems, methods, and apparatuses relating to a configurable spatial accelerator are described. In one embodiment, a processor includes a plurality of processing elements; and an interconnect network between the plurality of processing elements to receive an input of a dataflow graph comprising a plurality of nodes, wherein the dataflow graph is to be overlaid into the interconnect network and the plurality of processing elements with each node represented as a dataflow operator in the plurality of processing elements, and the plurality of processing elements is to perform an operation when an incoming operand set arrives at the plurality of processing elements. At least one of the plurality of processing elements includes a plurality of control inputs.
FILED	Saturday, July 01, 2017
APPL NO	15/640535
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 12/0802 (20130101) G06F 15/7867 (20130101) G06F 15/8015 (20130101) G06F 17/505 (20130101) Original (OR) Class Static Stores G11C 8/12 (20130101) Pulse Technique H03K 19/1778 (20130101) H03K 19/17736 (20130101) H03K 19/17756 (20130101) H03K 19/17764 (20130101) H03K 19/17776 (20130101)
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10445616 — Enhanced phase correlation for image registration

US 10445616	Tom et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Victor T. Tom (Bedford, Massachusetts); Stephen P. Delmarco (North Andover, Massachusetts); Helen F. Webb (Malden, Massachusetts)
ABSTRACT	An image registration system and method for matching images having fundamentally different characteristics. One exemplary feature of the system and method includes the use of an enhanced phase correlation method combined with a coarse sensor model to hypothesize and match a custom match metric to determine a best solution. The system and method may be operated on a non-transitory computer-readable medium storing a plurality of instructions which when executed by one or more processors causes the one or more processors to perform the image registration method utilizing the enhanced phase correlation.
FILED	Friday, January 22, 2016
APPL NO	15/004029
ART UNIT	2489 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/52 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/32 (20170101) G06T 2200/28 (20130101)
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10445642 — Unsupervised, supervised and reinforced learning via spiking computation

US 10445642	Modha
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Dharmendra S. Modha (San Jose, California)
ABSTRACT	The present invention relates to unsupervised, supervised and reinforced learning via spiking computation. The neural network comprises a plurality of neural modules. Each neural module comprises multiple digital neurons such that each neuron in a neural module has a corresponding neuron in another neural module. An interconnection network comprising a plurality of edges interconnects the plurality of neural modules. Each edge interconnects a first neural module to a second neural module, and each edge comprises a weighted synaptic connection between every neuron in the first neural module and a corresponding neuron in the second neural module.
FILED	Monday, May 23, 2016
APPL NO	15/162361
ART UNIT	2124 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Original (OR) Class G06N 3/049 (20130101) G06N 3/063 (20130101) G06N 3/088 (20130101)
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10446209 — Method and system for providing magnetic tunneling junction elements having improved performance through capping layer induced perpendicular anisotropy and memories using such magnetic elements

US 10446209	Watts et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Steven M. Watts (Mountain View, California); Zhitao Diao (Fremont, California); Xueti Tang (Fremont, California); Kiseok Moon (Pleasanton, California); Mohamad Towfik Krounbi (San Jose, California)
ASSIGNEE(S)	Samsung Semiconductor Inc. (San Jose, California)
INVENTOR(S)	Steven M. Watts (Mountain View, California); Zhitao Diao (Fremont, California); Xueti Tang (Fremont, California); Kiseok Moon (Pleasanton, California); Mohamad Towfik Krounbi (San Jose, California)
ABSTRACT	A method and system for providing a magnetic element and a magnetic memory utilizing the magnetic element are described. The magnetic element is used in a magnetic device that includes a contact electrically coupled to the magnetic element. The method and system include providing pinned, nonmagnetic spacer, and free layers. The free layer has an out-of-plane demagnetization energy and a perpendicular magnetic anisotropy corresponding to a perpendicular anisotropy energy that is less than the out-of-plane demagnetization energy. The nonmagnetic spacer layer is between the pinned and free layers. The method and system also include providing a perpendicular capping layer adjoining the free layer and the contact. The perpendicular capping layer induces at least part of the perpendicular magnetic anisotropy in the free layer. The magnetic element is configured to allow the free layer to be switched between magnetic states when a write current is passed through the magnetic element.
FILED	Friday, February 25, 2011
APPL NO	13/035726
ART UNIT	2627 — Selective Visual Display Systems
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 25/00 (20130101) B82Y 40/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/098 (20130101) Static Stores G11C 11/161 (20130101) G11C 11/1659 (20130101) G11C 11/1675 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/3254 (20130101) H01F 10/3286 (20130101) H01F 41/34 (20130101) H01F 41/307 (20130101) H01F 41/325 (20130101)
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10446307 — Magnetic field generators based on high magnetic permeability materials

US 10446307	Loftus et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	AOSense, Inc. (Sunnyvale, California)
ASSIGNEE(S)	AOSense, Inc. (Sunnyvale, California)
INVENTOR(S)	Thomas H. Loftus (Los Gatos, California); Mark A. Kasevich (Palo Alto, California); Arman Cingoz (Sunnyvale, California); Matthew Cashen (Gilroy, California)
ABSTRACT	A device for magnetic field generation includes a flux deliverer and a field shaper.
FILED	Tuesday, May 23, 2017
APPL NO	15/603020
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/12 (20130101) H01F 3/10 (20130101) H01F 3/14 (20130101) H01F 7/06 (20130101) Original (OR) Class H01F 7/20 (20130101) H01F 7/0278 (20130101)
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10446582 — Method of providing an imaging system and imaging system thereof

US 10446582	Smith et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Joseph Smith (Tempe, Arizona); Rita Bottesch (Mesa, Arizona); John Stowell (Tempe, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Joseph Smith (Tempe, Arizona); Rita Bottesch (Mesa, Arizona); John Stowell (Tempe, Arizona)
ABSTRACT	A method can include providing a scintillator structure. Providing the scintillator structure can include providing a scintillator support layer, providing a scintillator layer, and coupling the scintillator layer to the scintillator support layer. Meanwhile, the scintillator support layer has a substantially non-planar surface, the scintillator layer having a first surface and a second surface opposite the first surface and being configured to scintillate, and the first surface of the scintillator layer is coupled to the substantially non-planar surface of the scintillator support layer such that the second surface of the scintillator layer has a contour of the substantially non-planar surface of the scintillator support layer.
FILED	Tuesday, October 25, 2016
APPL NO	15/334143
ART UNIT	2893 — Semiconductors/Memory
CURRENT CPC	Diagnosis; Surgery; Identification A61B 2562/02 (20130101) A61B 2562/164 (20130101) Measurement of Nuclear or X-radiation G01T 1/2018 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/768 (20130101) H01L 21/6835 (20130101) H01L 21/30604 (20130101) H01L 23/15 (20130101) H01L 23/3192 (20130101) H01L 23/4985 (20130101) H01L 27/153 (20130101) H01L 27/1218 (20130101) Original (OR) Class H01L 27/1262 (20130101) H01L 27/14603 (20130101) H01L 27/14636 (20130101) H01L 27/14663 (20130101) H01L 29/78603 (20130101) H01L 33/0079 (20130101) H01L 2221/6835 (20130101) H01L 2221/68381 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101)
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10446701 — In-plane resonant-cavity infrared photodetectors with fully-depleted absorbers

US 10446701	Meyer et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jerry R. Meyer (Catonsville, Maryland); Igor Vurgaftman (Severna Park, Maryland); Chadwick Lawrence Canedy (Washington, District of Columbia); William W. Bewley (Falls Church, Virginia); Chul Soo Kim (Springfield, Virginia); Charles D. Merritt (Fairfax, Virginia); Michael V. Warren (Arlington, Virginia); Mijin Kim (Springfield, Virginia)
ABSTRACT	Resonant-cavity infrared photodetector (RCID) devices that include a thin absorber layer contained entirely within the resonant cavity. In some embodiments, the absorber is a single type-II InAs—GaSb interface situated between an AlSb/InAs superlattice n-type region and a p-type AlSb/GaSb region. In other embodiments, the absorber region comprises quantum wells formed on an upper surface of the n-type region. In other embodiments, the absorber region comprises a “W”-structured quantum well situated between two barrier layers, the “W”-structured quantum well comprising a hole quantum well sandwiched between two electron quantum wells. In other embodiments, the RCID includes a thin absorber region and an nBn or pBp active core within a resonant cavity. In some embodiments, the RCID is configured to absorb incident light propagating in the direction of the epitaxial growth of the RCID structure, while in other embodiments, it absorbs light propagating in the epitaxial plane of the structure.
FILED	Tuesday, April 09, 2019
APPL NO	16/378601
ART UNIT	2891 — Semiconductors/Memory
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) G01N 21/552 (20130101) G01N 21/3504 (20130101) G01N 21/7746 (20130101) Optical Elements, Systems, or Apparatus G02B 6/124 (20130101) G02B 6/12004 (20130101) G02B 2006/12061 (20130101) G02B 2006/12078 (20130101) G02B 2006/12123 (20130101) G02B 2006/12138 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/105 (20130101) H01L 31/109 (20130101) H01L 31/02327 (20130101) Original (OR) Class H01L 31/03046 (20130101)
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10446853 — Fluorine-based cathode materials for thermal batteries

US 10446853	Choi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Aviation and Missile Center (CCDC AVMC)
APPLICANT(S)	CFD Research Corporation (Huntsville, Alabama)
ASSIGNEE(S)	CFD Research Corporation (Huntsville, Alabama)
INVENTOR(S)	Pyoungho Choi (Huntsville, Alabama); Sameer Singhal (Huntsville, Alabama); Joe Don Edington (Chandler, Arizona)
ABSTRACT	A thermal battery can include: an anode of lithium alloy; a metal-fluoride cathode having Ni; and an electrolyte composition in contact with the anode and cathode. A thermal battery can also include: an anode of lithium alloy; a metal-fluoride cathode having an oxide selected from V₂O₅or LiVO₃; and an electrolyte composition in contact with the anode and cathode. In one aspect, a metal of the metal fluoride cathode includes Ni, Fe, V, Cr, Mn, Co, or mixture thereof. In one aspect, the metal-fluoride cathode includes NiF₂, FeF₃, VF₃, CrF₃, MnF₃, CoF₃, or a mixture thereof. A method of providing electricity can include: providing an electronic device having a thermal battery with a metal-fluoride cathode having Ni and/or having an oxide selected from V₂O₅or LiVO₃; and discharging the thermal battery to provide electricity.
FILED	Thursday, August 24, 2017
APPL NO	15/685665
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/06 (20130101) H01M 4/405 (20130101) H01M 4/582 (20130101) H01M 4/5815 (20130101) H01M 6/36 (20130101) Original (OR) Class H01M 2220/20 (20130101) H01M 2300/0054 (20130101) H01M 2300/0057 (20130101) H01M 2300/0062 (20130101)
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10447179 — Inertially operated piezoelectric energy harvesting electronic circuitry

US 10447179	Rastegar et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Armament Research, Development and Engineering Center (ARDEC)
APPLICANT(S)	Jahangir S Rastegar (Stony Brook, New York); Philip C Kwok (West Babylon, New York)
ASSIGNEE(S)	OMNITEK PARTNERS LLC (Ronkonkoma, New York)
INVENTOR(S)	Jahangir S Rastegar (Stony Brook, New York); Philip C Kwok (West Babylon, New York)
ABSTRACT	A device responsive to an acceleration pulse event, the device including: a piezoelectric device configured to generate a voltage over a duration responsive to one or more acceleration pulse events; an electrical storage device configured to receive a portion of the generated voltage to accumulate a charge; an energy dissipating device coupled to the electrical storage device and configured to dissipate the accumulated charge following the one or more acceleration pulse events and not to substantially dissipate the accumulated charge during the one or more acceleration pulse events; and a voltage limiting device coupled to the electrical storage device and configured to limit the portion of the generated voltage applied to the electrical storage device to a predetermined limit.
FILED	Saturday, November 04, 2017
APPL NO	15/803765
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Ammunition Fuzes; Arming or Safety Means Therefor F42C 11/02 (20130101) F42C 11/008 (20130101) Electric Machines Not Otherwise Provided for H02N 2/181 (20130101) Original (OR) Class H02N 2/183 (20130101)
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10447220 — Variable gain amplifier

US 10447220	Krishnamurthi et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Kathiravan Krishnamurthi (Westford, Massachusetts); Gregory M. Flewelling (Freeport, Maine)
ABSTRACT	A variable gain amplifier circuit including a first amplifier, a second amplifier, and a variable capacitor connected in series between the first amplifier and the second amplifier is disclosed. As a gain of the variable gain amplifier circuit varies, the input impedance, output impedance, noise figure and third-order output intercept point (OIP3) of the variable gain amplifier circuit remain unchanged.
FILED	Wednesday, March 07, 2018
APPL NO	15/914625
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Amplifiers H03F 1/26 (20130101) H03F 1/34 (20130101) H03F 7/04 (20130101) Original (OR) Class
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10447234 — Piezoelectric MEMS resonator with integrated phase change material switches

US 10447234	Rinaldi et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	Northeastern University (Boston, Massachusetts)
ASSIGNEE(S)	Northeastern University (Boston, Massachusetts)
INVENTOR(S)	Matteo Rinaldi (Boston, Massachusetts); Gwendolyn Hummel (Weymouth, Massachusetts)
ABSTRACT	A monolithic integration of phase change material (PCM) switches with a MEMS resonator is provided to implement switching and reconfiguration functionalities. MEMS resonator includes a piezoelectric material to control terminal connections to the electrodes. The PCM is operable between an ON state and an OFF state by application of heat, which causes the phase change material to change from an amorphous state to a crystalline state or from a crystalline state to an amorphous state, the amorphous state and the crystalline state each associated with one of the ON state and the OFF state. A method of fabricating the MEMS resonator with phase change material is provided. A reconfigurable filter system using the MEMS resonators is also provided.
FILED	Friday, April 17, 2015
APPL NO	15/304919
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/18 (20130101) H01L 45/06 (20130101) H01L 45/141 (20130101) H01L 45/144 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 3/02 (20130101) H03H 3/0073 (20130101) H03H 9/54 (20130101) H03H 9/131 (20130101) H03H 9/133 (20130101) Original (OR) Class H03H 9/205 (20130101) H03H 9/02228 (20130101) H03H 2003/027 (20130101) H03H 2009/155 (20130101)
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10447278 — JTL-based superconducting logic arrays and FPGAs

US 10447278	Reohr et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	William Robert Reohr (Severna Park, Maryland); Randall M. Burnett (Catonsville, Maryland); Randal L. Posey (Baltimore, Maryland)
ASSIGNEE(S)	Northrop Grumman Systems Corporation (Falls Church, Virginia)
INVENTOR(S)	William Robert Reohr (Severna Park, Maryland); Randall M. Burnett (Catonsville, Maryland); Randal L. Posey (Baltimore, Maryland)
ABSTRACT	Superconducting logic arrays (SLAs) and field-programmable gate arrays (FPGAs) that are based on Josephson transmission lines (JTLs) accommodate reciprocal quantum logic (RQL) compliant binary input signals and provide RQL-compliant output signals that are evaluations of generalized logic functions. Each JTL-based superconducting FPGA (JTLBSFPGA) incorporates multiple JTL-based SLAs (JTLBSLAs) connected together. Each JTLBSLA includes an array of software-programmable and/or mask-programmed logic cells that output products of inputs and cell states, such that the JTLBSLAs output evaluations of sum-of-products functions. New JTLBSLA logic cells are described, including some that provide programmable cell states via magnetic Josephson junctions (MJJs). JTLBSFPGAs provide area efficiency and clock speed advantages over CMOS FPGAs. Unlike SLAs based on Josephson magnetic random access memory (JMRAM), JTLBSLAs do not require word line drivers, flux pumps, or sense amplifiers. Because JTLBSLAs and JTLBSFPGAs are RQL-compliant, they can also include RQL gates connected within or between them, without signal conversion circuitry.
FILED	Tuesday, July 17, 2018
APPL NO	16/037587
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 11/44 (20130101) Pulse Technique H03K 19/195 (20130101) Original (OR) Class H03K 19/1776 (20130101) H03K 19/17708 (20130101) H03K 19/17736 (20130101)
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10447293 — Count time measurement analog to digital conversion

US 10447293	Hairston
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Allen W Hairston (Andover, Massachusetts)
ABSTRACT	A system and method is provided for analog to digital conversion, the system having: a front end whereby a current is converted to digital pulses; and a back end with a coarse conversion unit outputting a pulse count; and a fine conversion unit outputting a count time measurement count; wherein said back end unit is configured to combine said pulse count and said count time measurement to produce a high dynamic range output, said output being the product of the one more than the pulse count and the integration time divided by the sum of the integration time and the count time management count.
FILED	Friday, November 30, 2018
APPL NO	16/206151
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Coding; Decoding; Code Conversion in General H03M 1/50 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/378 (20130101)
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10447710 — Self-shielding dynamic network architecture

US 10447710	Li et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Cryptonite, LLC (Rockville, Maryland)
ASSIGNEE(S)	Cryptonite, LLC (Rockville, Maryland)
INVENTOR(S)	Jason Li (Potomac, Maryland); Justin Yackoski (Gaithersburg, Maryland); Brian Kambach (Rockville, Maryland); Renato Levy (North Potomac, Maryland); Nicholas Evancich (Clarksburg, Maryland)
ABSTRACT	A shielding is provided to prevent attacks on network architecture or reduce the impact thereof. The system reconfigures the network differently for each user, operating system, and host and the configuration changes as time passes. The system can use dynamic redirection to create a reconfigurable network, and include intermediary nodes to dynamically reconfigure the network infrastructure for all traffic.
FILED	Wednesday, June 03, 2015
APPL NO	14/729521
ART UNIT	2436 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/0281 (20130101) H04L 63/0876 (20130101) H04L 63/1416 (20130101) Original (OR) Class H04L 63/1425 (20130101)
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10448143 — Wireless communications headset system employing a loop transmitter that fits around the pinna

US 10448143	Parkins
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Red Tail Hawk Corporation (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Red Tail Hawk Corporation (Philadelphia, Pennsylvania)
INVENTOR(S)	John W. Parkins (Ithaca, New York)
ABSTRACT	A wireless communications headset system for double hearing protection systems that eliminates the problems associated with typical wireless communications systems. The system employs a magnetic-field coupled wireless link from a loop transmitter to a magnetic field receiver. Current through the transmitter wire loops generates magnetic flux which passes through a communications earplug. The earplug has a receiver for converting the magnetic flux to electrical voltage, and this voltage is used to drive a speaker within the earplug. The transmitter can be easily installed into aviation headsets. The loop transmitter has an open center sized so that it fits around the pinna of the human ear enabling a close position to the communications earplug. This close position is advantageous if an efficient system is desired.
FILED	Tuesday, April 26, 2016
APPL NO	15/138603
ART UNIT	2656 — Digital Audio Data Processing
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 11/08 (20130101) A61F 11/14 (20130101) Antennas, i.e Radio Aerials H01Q 1/273 (20130101) H01Q 7/08 (20130101) Telephonic Communication H04M 1/05 (20130101) H04M 1/215 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/08 (20130101) H04R 1/1016 (20130101) H04R 1/1083 (20130101) H04R 1/1091 (20130101) Original (OR) Class H04R 3/04 (20130101) H04R 2201/107 (20130101) H04R 2420/07 (20130101)
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10448152 — Systems and methods for monitoring and classifying marine animals based on acoustic signals

US 10448152	Makris et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate of Geosciences (GEO) Division of Ocean Sciences (OCE)
APPLICANT(S)	Northeastern Univerisity (Boston, Massachusetts)
ASSIGNEE(S)	Northeastern University (Boston, Massachusetts)
INVENTOR(S)	Purnima Ratilal Makris (Boston, Massachusetts); Nicholas Constantine Makris (Boston, Massachusetts)
ABSTRACT	Disclosed herein are apparatus, devices, and methods for monitoring marine animals, such as whales, and other marine mammals, and fish groups within a marine environment. A marine animal monitoring system may include an acoustic receiver array having a high-resolution directional sensing capacity using large-aperture densely-sampled coherent ocean acoustic receiver arrays operative to enhance detection range and localization accuracy of marine mammal vocalizations and fish acoustic signals. The acoustic receiver array may generate acoustic signal information based on acoustic signals sensed at the array. The marine monitoring system may operate to generate marine animal information based on the acoustic signal information, such as marine animal location, species, call type, and/or the like.
FILED	Wednesday, September 21, 2016
APPL NO	15/271890
ART UNIT	2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC	Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 17/26 (20130101) G10L 25/51 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/44 (20130101) Original (OR) Class H04R 1/265 (20130101) H04R 3/005 (20130101) H04R 29/008 (20130101) H04R 2430/03 (20130101) H04R 2430/20 (20130101)
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10448524 — High voltage power module

US 10448524	Cole et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Cree Fayetteville, Inc. (Fayetteville, Arkansas)
ASSIGNEE(S)	Cree, Inc. (Durham, North Carolina)
INVENTOR(S)	Zachary Cole (Summers, Arkansas); Brandon Passmore (Fayetteville, Arkansas)
ABSTRACT	A power module includes a number of sub-modules connected via removable jumpers. The removable jumpers allow the connections between one or more power semiconductor die in the sub-modules to be reconfigured, such that when the removable jumpers are provided, the power module has a first function, and when the removable jumpers are removed, the power module has a second function. The removable jumpers may also allow for independent testing of the sub-modules. The power module may also include a multi-layer printed circuit board (PCB), which is used to connect one or more contacts of the power semiconductor die. The multi-layer PCB reduces stray inductance between the contacts and therefore improves the performance of the power module.
FILED	Friday, October 27, 2017
APPL NO	15/796138
ART UNIT	2847 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/4093 (20130101) H01L 23/5382 (20130101) H01L 25/072 (20130101) H01L 25/115 (20130101) H01L 25/162 (20130101) H01L 29/78 (20130101) H01L 29/1608 (20130101) H01L 2224/49111 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/088 (20130101) H02M 7/003 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0298 (20130101) H05K 5/0065 (20130101) Original (OR) Class H05K 5/0069 (20130101) H05K 2201/10166 (20130101)
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RE047651 — Stackable electronic package and method of fabricating same

US RE47651	Sabatini et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	James Sabatini (Scotia, New York); Christopher James Kapusta (Delanson, New York); Glenn Forman (Niskayuna, New York)
ABSTRACT	An electronic package includes a first layer having a first surface, the first layer includes a first device having a first electrical node, and a first contact pad in electrical communication with the first electrical node and positioned within the first surface. The package includes a second layer having a second surface and a third surface, the second layer includes a first conductor positioned within the second surface and a second contact pad positioned within the third surface and in electrical communication with the first conductor. A first anisotropic conducting paste (ACP) is positioned between the first contact pad and the first conductor to electrically connect the first contact pad to the first conductor such that an electrical signal may pass therebetween.
FILED	Wednesday, January 25, 2017
APPL NO	15/415549
ART UNIT	3991 — Central Reexamination Unit (Chemical)
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/5385 (20130101) H01L 23/5389 (20130101) H01L 24/19 (20130101) H01L 24/82 (20130101) H01L 25/16 (20130101) H01L 25/50 (20130101) Original (OR) Class H01L 25/0657 (20130101) H01L 2224/04105 (20130101) H01L 2224/24137 (20130101) H01L 2224/73267 (20130101) H01L 2224/82039 (20130101) H01L 2224/92144 (20130101) H01L 2225/0652 (20130101) H01L 2225/06524 (20130101) H01L 2924/00 (20130101) H01L 2924/014 (20130101) H01L 2924/14 (20130101) H01L 2924/01006 (20130101) H01L 2924/01029 (20130101) H01L 2924/01033 (20130101) H01L 2924/01047 (20130101) H01L 2924/01075 (20130101) H01L 2924/01079 (20130101) H01L 2924/01082 (20130101) H01L 2924/12042 (20130101) H01L 2924/12042 (20130101) H01L 2924/15192 (20130101) H01L 2924/15311 (20130101) H01L 2924/15331 (20130101) H01L 2924/18162 (20130101) H01L 2924/19041 (20130101) H01L 2924/19042 (20130101) H01L 2924/19043 (20130101)
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Department of Health and Human Services (HHS)

10441185 — Flexible and stretchable electronic systems for epidermal electronics

US 10441185	Rogers et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Neurological Disorders and Stroke (NINDS) Tissue Engineering Resource Center (TERC) National Science Foundation (NSF)
APPLICANT(S)	John A. Rogers (Champaign, Illinois); Dae-Hyeong Kim (Champaign, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	John A. Rogers (Champaign, Illinois); Dae-Hyeong Kim (Champaign, Illinois)
ABSTRACT	Provided herein are skin-mounted biomedical devices and methods of making and using biomedical devices for sensing and actuation applications. For example, flexible and/or stretchable biomedical devices are provided, including electronic devices useful for establishing conformal contact with the skin of a subject. Devices disclosed herein can comprise a plurality of sensing and/or actuating devices provided as part of a skin-mounted flexible or stretchable electronic circuit.
FILED	Friday, June 08, 2012
APPL NO	13/492636
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/076 (20130101) A61B 5/0422 (20130101) A61B 5/0478 (20130101) A61B 5/0492 (20130101) A61B 5/0537 (20130101) A61B 5/1104 (20130101) A61B 5/1107 (20130101) A61B 5/04085 (20130101) Original (OR) Class A61B 5/04284 (20130101) A61B 5/4875 (20130101) A61B 5/6867 (20130101) A61B 2562/02 (20130101) A61B 2562/12 (20130101) A61B 2562/029 (20130101) A61B 2562/046 (20130101) A61B 2562/066 (20130101) A61B 2562/164 (20130101) A61B 2562/0261 (20130101) A61B 2562/0271 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/36 (20130101) A61N 1/0472 (20130101) A61N 1/0587 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/3121 (20130101) H01L 23/3192 (20130101) H01L 27/1218 (20130101) H01L 29/7869 (20130101) H01L 29/78603 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2924/3011 (20130101) H01L 2924/3025 (20130101) H01L 2924/12044 (20130101) H01L 2924/19041 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/147 (20130101) H05K 1/189 (20130101) H05K 1/0283 (20130101) H05K 3/323 (20130101) H05K 2201/09263 (20130101)
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10441225 — Predicting disease recurrence following trimodality therapy in non-small cell lung cancer using computed tomography derived radiomic features and clinico-pathologic features

US 10441225	Madabhushi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Medical Research Acquisition Activity (USAMRAA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Center for Research Resources (NCRR) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Anant Madabhushi (Shaker Heights, Ohio); Mohammadhadi Khorrami (Cleveland, Ohio); Vamsidhar Velcheti (Pepper Pike, Ohio)
ABSTRACT	Embodiments include operations, apparatus, methods and other embodiments that access a baseline CT image of a region of tissue (ROT) demonstrating non-small cell lung cancer (NSCLC), segment a tumoral region represented in the baseline CT image; define a peritumoral region by dilating the tumoral boundary; extract a set of tumoral radiomic features from the tumoral region, a set of peritumoral radiomic features from the peritumoral region, and a set of clinico-pathologic features from the baseline CT image; provide the set of tumoral radiomic features, peritumoral radiomic features, and clinico-pathologic features to a machine learning classifier; receive, from the machine learning classifier, a time-to-recurrence post trimodality therapy (TMT) prediction, based on the set of tumoral radiomic features, peritumoral radiomic features, and clinico-pathologic features; generate a classification of the ROT as an MPR responder or MPR non-responder based, at least in part, on the time-to-recurrence post-TMT prediction; and display the classification.
FILED	Monday, December 31, 2018
APPL NO	16/236675
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/7267 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6284 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0016 (20130101) G06T 7/155 (20170101) G06T 2207/10081 (20130101) G06T 2207/20081 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101)
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10441371 — Concentric tube robot

US 10441371	Hendrick et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Vanderbilt University (Nashville, Ohio)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	Richard J. Hendrick (Nashville, Tennessee); Robert J. Webster, III (Nashville, Tennessee); S. Duke Herrell (Nashville, Tennessee); Philip J. Swaney (Nashville, Tennessee); Ray Lathrop (Indianapolis, Indiana)
ABSTRACT	A robotic surgical apparatus includes at least two tubes having a nested, concentric configuration with an inner tube positioned in an outer tube. The tubes are configured to deliver surgical therapy. A first tube carrier connected to the outer tube and a second tube carrier connected to the inner tube. The first tube carrier and its associated outer tube and the second tube carrier and its associated inner tube form a robotic arm assembly. An actuator for actuating the robotic arm assembly is configured to receive the robotic arm assembly via a tube insertion interface into which the robotic arm assembly can be inserted.
FILED	Monday, October 03, 2016
APPL NO	15/283775
ART UNIT	3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/05 (20130101) A61B 1/00039 (20130101) A61B 1/00087 (20130101) A61B 1/00101 (20130101) A61B 1/00133 (20130101) A61B 17/00234 (20130101) A61B 34/30 (20160201) Original (OR) Class A61B 34/72 (20160201) A61B 2017/00296 (20130101) A61B 2017/00318 (20130101) A61B 2017/00345 (20130101) A61B 2034/301 (20160201) A61B 2034/302 (20160201) A61B 2034/742 (20160201)
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10441531 — Protein stabilizing factors

US 10441531	Chung et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Bloodworks (Seattle, Washington)
ASSIGNEE(S)	Bloodworks (Seattle, Washington)
INVENTOR(S)	Dominic Chung (Bellevue, Washington); Jose Aron Lopez (Seattle, Washington); Minhua Ling (Kenmore, Washington); Junmei Chen (Seattle, Washington); Xiaoyun Fu (Kenmore, Washington)
ABSTRACT	Compositions and methods are described for preventing or reducing protein loss due to protein aggregation, denaturation, and adsorption to surfaces. Also described are compositions and methods for preventing or reducing the fouling or clogging of medical devices that come into contact with blood, such as catheters. Also described are methods to treat diseases caused by activation of the microvasculature.
FILED	Tuesday, November 12, 2013
APPL NO	14/442387
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 47/42 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/16 (20130101) A61L 29/048 (20130101) A61L 29/085 (20130101) A61L 29/143 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 31/143 (20130101) A61L 2300/424 (20130101) A61L 2400/18 (20130101) Peptides C07K 14/755 (20130101) C07K 14/775 (20130101)
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10441549 — Methods of preparing polyelectrolyte complex nanoparticles

US 10441549	Mao et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Hai-Quan Mao (Baltimore, Maryland); Jose Luis Santos (Rockville, Maryland); Yong Ren (Baltimore, Maryland); John-Michael Williford (Chicago, Illinois)
ABSTRACT	The presently disclosed subject matter provides methods for continuously generating uniform polyelectrolyte complex (PEC) nanoparticles comprising: flowing a first stream comprising one or more water-soluble polycationic polymers at a first variable flow rate into a confined chamber; flowing a second stream comprising one or more water-soluble polyanionic polymers at a second variable flow rate into the confined chamber; and impinging the first stream and the second stream in the confined chamber until the Reynolds number is from about 1,000 to about 20,000, thereby causing the one or more water-soluble polycationic polymers and the one or more water-soluble polyanionic polymers to undergo a polyelectrolyte complexation process that continuously generates PEC nanoparticles. Compositions produced from the presently disclosed methods and a device for producing the compositions are also disclosed.
FILED	Wednesday, July 27, 2016
APPL NO	15/221189
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/5115 (20130101) A61K 9/5146 (20130101) A61K 9/5161 (20130101) A61K 9/5169 (20130101) A61K 9/5192 (20130101) Original (OR) Class A61K 47/61 (20170801) A61K 47/6455 (20170801)
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10441574 — Treatment for wolfram syndrome and other endoplasmic reticulum stress disorders

US 10441574	Urano et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Fumihiko Urano (St. Louis, Missouri); Simin Lu (St. Louis, Missouri)
ASSIGNEE(S)	Washington University (St. Louis, Missouri)
INVENTOR(S)	Fumihiko Urano (St. Louis, Missouri); Simin Lu (Shanghai, China PRC)
ABSTRACT	The present invention generally relates to a method of treating or preventing an endoplasmic reticulum stress disorder in subjects, such as a method of treating or preventing Wolfram syndrome.
FILED	Friday, November 13, 2015
APPL NO	15/526663
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/4178 (20130101) Original (OR) Class A61K 31/4178 (20130101) A61K 38/177 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101)
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10441588 — Methods and compositions for treating bacterial infection

US 10441588	Sun et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Curators of the University of Missouri (Columbia, Missouri); Nanova, Inc. (Columbia, Missouri)
ASSIGNEE(S)	Curators of the University of Missouri (Columbia, Missouri); Nanova, Inc. (Columbia, Missouri)
INVENTOR(S)	Hongmin Sun (Columbia, Missouri); David W. Anderson (Columbia, Missouri); Feng Qi (Columbia, Missouri)
ABSTRACT	The present disclosure relates to chemical compounds, methods for their discovery, and their therapeutic and research use. In particular, the present disclosure provides compounds as therapeutic agents against bacterial infections (e.g., biofilms). The present disclosure also provides topical formulations for use in methods for treating bacterial infections.
FILED	Thursday, September 21, 2017
APPL NO	15/711648
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/505 (20130101) A61K 31/517 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/527 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 47/06 (20130101) A61K 47/44 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 31/16 (20130101) A61L 2300/404 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101)
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10441596 — Methods and compositions related to glucocorticoid receptor antagonists and breast cancer

US 10441596	Pan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The University of Chicago (Chicago, Illinois)
ASSIGNEE(S)	The University of Chicago (Chicago, Illinois)
INVENTOR(S)	Deng Pan (Chicago, Illinois); Masha Kocherginsky (Chicago, Illinois); Suzanne D. Conzen (Park Ridge, Illinois)
ABSTRACT	Embodiments of the invention are directed to methods of determining the prognosis of a breast cancer patient by evaluating the activity of the glucocorticoid receptor in tumor cells. Other embodiment include methods of treating breast cancer cells, particularly, chemo-resistant cells, with a glucocorticoid receptor antagonist and an anticancer agent or compound.
FILED	Friday, March 03, 2017
APPL NO	15/448827
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/282 (20130101) A61K 31/337 (20130101) A61K 31/357 (20130101) A61K 31/567 (20130101) A61K 31/575 (20130101) Original (OR) Class A61K 31/575 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 33/24 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101)
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10441601 — Method for treating schizophrenia

US 10441601	Zakharenko
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee)
ASSIGNEE(S)	ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (Memphis, Tennessee)
INVENTOR(S)	Stanislav S. Zakharenko (Collierville, Tennessee)
ABSTRACT	The invention is directed to a method for treating the 22q11 deletion syndrome (22q11 DS) and schizophrenia (SCZ) by replenishment of decreased levels of miR-338-3p in thalamic neurons.
FILED	Thursday, June 30, 2016
APPL NO	15/740687
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 31/713 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/861 (20130101) C12N 2310/141 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/302 (20130101)
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10441607 — Multifunctional linker technology containing an N4 group

US 10441607	Azhdarinia et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S)	THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Ali Azhdarinia (Houston, Texas); Sukhen C. Ghosh (Houston, Texas); Nathaniel L. Wilganowski (Houston, Texas); Eva M. Sevick-Muraca (Houston, Texas)
ABSTRACT	In some aspects, the present disclosure provides compositions comprising an N4-based MMC ligand, a cell targeting group, and a fluorophore or a therapeutic compound comprising a formula: wherein the variables are as defined herein. In some embodiments, these compositions may be used in the imaging techniques or in the treatment of a disease or disorder such as cancer.
FILED	Wednesday, February 22, 2017
APPL NO	15/439515
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 33/02 (20130101) Original (OR) Class A61K 33/24 (20130101) A61K 38/16 (20130101) A61K 39/385 (20130101) A61K 39/395 (20130101) A61K 49/0021 (20130101) A61K 2039/5152 (20130101)
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10441637 — Methods for structural determination of selenium derivatized nucleic acid complexes

US 10441637	Huang
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	SeNA Research, Inc. (Marietta, Georgia)
ASSIGNEE(S)	SeNA Research, Inc. (Marietta, Georgia)
INVENTOR(S)	Zhen Huang (Marietta, Georgia)
ABSTRACT	Methods for crystallizing a molecule of interest, such as a polypeptide, in complex with nucleic acid, including contacting the molecule of interest with selenium-derivatized nucleic acid and crystallizing the molecule of interest/selenium-derivatized nucleic acid complex are provided. Methods for determining the X-ray crystal structure of molecule of interest/selenium-derivatized nucleic acid complexes are also provided. Typically, the method of X-ray crystal structural determination includes selenium single-wavelength anomalous phasing of the selenium-derivatized nucleic acid. In some embodiments the phases for the X-ray crystal structure of the molecule of interest are not provided from another crystal. Also disclosed are methods of affecting a biological process by administering a functional nucleic acid to a cell or a subject and/or by bringing into contact a nuclease and a functional nucleic acid, where the functional nucleic acid is selenium-derivatized nucleic acid.
FILED	Friday, November 21, 2014
APPL NO	15/038242
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) Original (OR) Class A61K 47/61 (20170801) Peptides C07K 1/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) Enzymes C12Y 301/26004 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101)
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10441642 — Immunogenic compositions and vaccines for preventing or treating filarial disease

US 10441642	Mitre et al.
FUNDED BY	Department of Defense (DOD) United States Special Operations Command (SOCOM) Uniformed Services University of the Health Sciences (USUHS) Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF) Department of Health and Human Services (HHS)
APPLICANT(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland); The United States Government, as Represented by the Secretary of the Department of Health and Human (Washington, District of Columbia)
ASSIGNEE(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland); The United States Government, as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Edward E. Mitre (Rockville, Maryland); Christopher Morris (North Potomac, Maryland); Sasisekhar Bennuru (Rockville, Maryland); Thomas Nutman (Chevy Chase, Maryland)
ABSTRACT	The present disclosure is directed to an immunogenic composition including: at least one or at least two isolated polypeptides or immunogenic fragments thereof, and optionally a pharmaceutically acceptable carrier, wherein each polypeptide is expressed on a luminal surface of an intestine of a filarial worm, wherein each polypeptide is expressed at a level at least two-fold higher in the intestine in comparison to the level of expression of each polypeptide in a reproductive tract or a body wall of the filarial worm, wherein each isolated polypeptide has at least one transmembrane domain, and wherein each polypeptide is a non-mitochondrial polypeptide. Also provided herein is a method for preventing or treating a filarial disease.
FILED	Thursday, March 17, 2016
APPL NO	15/558336
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/1767 (20130101) A61K 39/0003 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/55566 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/10 (20180101) Peptides C07K 14/4354 (20130101)
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10441644 — H3.3 CTL peptides and uses thereof

US 10441644	Okada et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Hideho Okada (Mill Valley, California); Yafei Hou (Palo Alto, California)
ABSTRACT	Peptides that generate an immune response to glioma-related H3.3 proteins and methods of their use are provided.
FILED	Monday, June 05, 2017
APPL NO	15/613837
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/03 (20130101) A61K 38/17 (20130101) A61K 38/19 (20130101) A61K 38/1764 (20130101) A61K 39/0011 (20130101) Original (OR) Class Peptides C07K 14/4748 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/5014 (20130101)
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10441646 — Infectious plasmodium sporozoites grown in vitro

US 10441646	Eappen et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Congressionally Directed Medical Research Programs (CDMRP) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	SANARIA INC. (Rockville, Maryland)
ASSIGNEE(S)	Sanaria Inc. (Rockville, Maryland)
INVENTOR(S)	Abraham G. Eappen (Ellicott City, Maryland); Stephen L. Hoffman (Gaithersburg, Maryland)
ABSTRACT	The application is directed to in vitro-reared Plasmodium sporozoites of human host range wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same. Provided herein are in vitro-reared infectious Plasmodium sporozoites (SPZ) of human host range, particularly P. falciparum, P. vivax, P. ovale, P. malariae, and P. knowlesi, wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same.
FILED	Friday, December 29, 2017
APPL NO	15/858574
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/015 (20130101) Original (OR) Class A61K 2039/52 (20130101) A61K 2039/522 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/10 (20130101) Technologies for Adaptation to Climate Change Y02A 50/412 (20180101)
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10441669 — Multifunctional chelators, complexes, and compositions thereof, and methods of using same

US 10441669	Chong
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	ILLINOIS INSTITUTE OF TECHNOLOGY (Chicago, Illinois)
ASSIGNEE(S)	ILLINOIS INSTITUTE OF TECHNOLOGY (Chicago, Illinois)
INVENTOR(S)	Hyun-Soon Chong (Chicago, Illinois)
ABSTRACT	Multifunctional chelators, metal complexes thereof, compositions thereof, and methods of making and use in diagnostic imaging and treatment of cellular disorders.
FILED	Monday, October 06, 2014
APPL NO	15/027104
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 51/0474 (20130101) A61K 51/0482 (20130101) Original (OR) Class Heterocyclic Compounds C07D 255/02 (20130101) C07D 257/02 (20130101) C07D 401/12 (20130101)
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10441681 — Materials and methods for nerve grafting

US 10441681	Muir
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S)	David F. Muir (Gainesville, Florida)
ABSTRACT	The subject invention pertains to compositions and methods for promoting repair of damaged nerve tissue using nerve grafts and preparation of nerve grafts. The compositions and methods of the subject invention can be employed to restore the continuity of nerve interrupted by disease, traumatic events or surgical procedures. Compositions of the subject invention comprise one or more chondroitin sulfate proteoglycan (CSPG)-degrading enzymes that promote axonal penetration into damaged nerve tissue and nerve graft. The invention also concerns methods for promoting repair of damaged nerve tissue using the present compositions and nerve tissue treated according to such methods. The invention also includes storage solutions for nerve tissue.
FILED	Tuesday, August 02, 2016
APPL NO	15/226409
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) A61K 35/30 (20130101) A61K 38/51 (20130101) A61K 38/51 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/227 (20130101) A61L 27/383 (20130101) A61L 27/3604 (20130101) A61L 27/3675 (20130101) A61L 27/3683 (20130101) A61L 27/3687 (20130101) Original (OR) Class A61L 27/3878 (20130101) A61L 31/047 (20130101) A61L 2430/32 (20130101)
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10441687 — Wnt/beta-catenin inhibitor-eluting endovascular stent

US 10441687	Sibinga et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York)
ASSIGNEE(S)	Albert Einstein College of Medicine (Bronx, New York)
INVENTOR(S)	Nicholas Ernst Smit Sibinga (Chappaqua, New York); Dario Fernando Riascos-Bernal (Bronx, New York)
ABSTRACT	A product comprising a stent for a human blood vessel which comprises (i) a scaffold which is impregnated with, adsorbed with, or coated with an inhibitor of a Wnt/p-catenin pathway, or (ii) a scaffold coated with a polymer, which polymer is impregnated with, adsorbed with, or coated with an inhibitor of a Wnt/p-catenin pathway, and methods of use to reduce the risk of restenosis.
FILED	Wednesday, November 05, 2014
APPL NO	15/028449
ART UNIT	1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/10 (20130101) Original (OR) Class A61L 31/16 (20130101) A61L 2300/432 (20130101) A61L 2420/06 (20130101)
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10441760 — Self-actuating chemomechanical devices for delivery and extended release of therapeutic agents in the gastrointestinal tract

US 10441760	Selaru et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) NIH Office of the Director (NIHOD)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Florin M. Selaru (Catonsville, Maryland); David H. Gracias (Baltimore, Maryland); Joyce Breger (Baltimore, Maryland)
ABSTRACT	The presently disclosed delivery systems utilize microtools, also referred to as theragrippers, to deliver a drug or other therapeutic agent to targeted tissue. More particularly, the drug delivery system and methods provide a delivery system that is capable of anchoring to a tissue site and then delivering a drug or therapeutic agent to the tissue directly to or in the vicinity of the site over an extended period of time. Any number of theragrippers may be deployed as desired to deliver different doses of a desired drug or therapeutic agent. The theragrippers also can be biodegradable such that they remain in place for an extended period of time and then degrade without adversely affecting the surrounding tissue.
FILED	Monday, March 03, 2014
APPL NO	14/195446
ART UNIT	3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/002 (20130101) Original (OR) Class
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10441768 — Bioactive components conjugated to substrates of microneedle arrays

US 10441768	Falo, Jr. et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Louis D. Falo, Jr. (Wexford, Pennsylvania); Geza Erdos (Wexford, Pennsylvania)
ABSTRACT	Microneedle arrays and methods of forming the same can include one or more bioactive components bonded to a biocompatible material such that the one or more bioactive components are cleavable in vivo to release the bioactive component from the biocompatible material.
FILED	Friday, March 18, 2016
APPL NO	15/074917
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0023 (20130101) A61M 2037/0046 (20130101) A61M 2037/0053 (20130101) A61M 2037/0061 (20130101) A61M 2202/0007 (20130101) A61M 2202/0057 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/025 (20130101) B29C 39/123 (20130101) B29C 41/22 (20130101) B29C 41/34 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2001/08 (20130101) B29K 2995/006 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101) B29L 2031/756 (20130101) B29L 2031/7544 (20130101)
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10441782 — Therapy delivery devices and methods for non-damaging neural tissue conduction block

US 10441782	Bhadra et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Niloy Bhadra (Cleveland Heights, Ohio); Kevin L. Kilgore (Avon Lake, Ohio); Narendra Bhadra (Chesterland, Ohio); Jesse Wainright (Willoughby Hills, Ohio); Tina Vrabec (Willoughby Hills, Ohio); Manfred Franke (South Euclid, Ohio)
ABSTRACT	Devices and methods for blocking signal transmission through neural tissue. One step of a method includes placing a therapy delivery device into electrical communication with the neural tissue. The therapy delivery device includes an electrode contact having a high charge capacity material. A multi-phase direct current (DC) can be applied to the neural tissue without damaging the neural tissue. The multi-phase DC includes a cathodic DC phase and anodic DC phase that collectively produce a neural block and reduce the charge delivered by the therapy delivery device. The DC delivery can be combined with high frequency alternating current (HFAC) block to produce a system that provides effective, safe, long term block without inducing an onset response.
FILED	Tuesday, August 21, 2018
APPL NO	16/106092
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/06 (20130101) A61N 1/20 (20130101) A61N 1/0556 (20130101) Original (OR) Class A61N 1/36064 (20130101) A61N 1/36067 (20130101) A61N 1/36071 (20130101)
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10441805 — Method and device for three-stage atrial cardioversion therapy

US 10441805	Efimov et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Washington University (St. Louis, Missouri)
ASSIGNEE(S)	The Washington University (St. Louis, Missouri)
INVENTOR(S)	Igor R. Efimov (Wildwood, Missouri); Wenwen Li (St. Louis, Missouri); Ajit Janardhan (St. Louis, Missouri)
ABSTRACT	Methods and apparatus for a three-stage atrial cardioversion therapy that treats atrial arrhythmias within pain tolerance thresholds of a patient. An implantable therapy generator adapted to generate and selectively deliver a three-stage atrial cardioversion therapy and at least two leads, each having at least one electrode adapted to be positioned proximate the atrium of the patient. The device is programmed for delivering a three-stage atrial cardioversion therapy via both a far-field configuration and a near-field configuration of the electrodes upon detection of an atrial arrhythmia. The three-stage atrial cardioversion therapy includes a first stage for unpinning of one or more singularities associated with an atrial arrhythmia, a second stage for anti-repinning of the one or more singularities, both of which are delivered via the far-field configuration of the electrodes, and a third stage for extinguishing of the one or more singularities delivered via the near-field configuration of the electrodes.
FILED	Monday, October 09, 2017
APPL NO	15/727803
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/395 (20130101) A61N 1/3624 (20130101) A61N 1/3956 (20130101) Original (OR) Class
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10441820 — Systems and methods for opening of a tissue barrier in primates

US 10441820	Konofagou et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Institute on Aging (NIA) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Mental Health (NIMH) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	The Trustees of Columbia University in the Ciy of New York (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Elisa E. Konofagou (New York, New York); Fabrice Marquet (New York, New York); Yao-Sheng Tung (New York, New York)
ABSTRACT	Systems and methods for cavitation-guided opening of a targeted region of tissue within a primate skull are provided. In one example, a method includes delivering one or more microbubbles to proximate the targeted region, applying an ultrasound beam, using a transducer, through the skull of the primate to the targeted region to open the tissue, transcranially acquiring acoustic emissions produced from an interaction between the one or more microbubbles and the tissue, and determining a cavitation spectrum from the acquired acoustic emissions.
FILED	Tuesday, November 26, 2013
APPL NO	14/091010
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 8/481 (20130101) A61B 8/0808 (20130101) A61B 17/2258 (20130101) A61B 90/10 (20160201) A61B 2017/00106 (20130101) A61B 2017/22008 (20130101) A61B 2017/22089 (20130101) A61B 2090/378 (20160201) A61B 2503/40 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0039 (20130101)
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10441950 — Method for transferring a target between locations

US 10441950	Beebe et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	David J. Beebe (Monona, Wisconsin); Ben P. Casavant (Madison, Wisconsin); David J. Guckenberger (Oconomowoc, Wisconsin); Scott M. Berry (Madison, Wisconsin)
ABSTRACT	A device and method are proved for transferring a target from a first location to a second location. The target is bound to solid phase substrate to form a target bound solid phase substrate. The device includes transfer surface for receiving the target bound solid phase substrate thereon for transfer. The transfer surface movable between a first position wherein the transfer surface is aligned with the first location and spaced therefrom by a distance and a second position wherein the transfer surface is aligned with the second location. An alignment structure aligns the transfer surface with respect to the second location, with the transfer surface in the second position. A force is movable between an attraction position wherein the target bound solid phase substrate are drawn toward the transfer surface and a discharge position wherein the target bound solid phase substrate are free of the force.
FILED	Tuesday, July 17, 2018
APPL NO	16/037153
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) Original (OR) Class B01L 3/563 (20130101) B01L 3/5088 (20130101) B01L 3/50825 (20130101) B01L 2200/025 (20130101) B01L 2200/0657 (20130101) B01L 2200/0668 (20130101) B01L 2300/042 (20130101) B01L 2400/021 (20130101) B01L 2400/043 (20130101)
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10442166 — Hydrophilic, yet slippery solid surfaces

US 10442166	Kota et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Science Foundation (NSF)
APPLICANT(S)	Colorado State University Research Foundation (Fort Collins, Colorado)
ASSIGNEE(S)	Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S)	Arun K. Kota (Fort Collins, Colorado); Hamed Vahabi (Fort Collins, Colorado)
ABSTRACT	In this work, a hydrophilic, yet slippery solid surface was developed. Because the surfaces are hydrophilic, there is significant affinity between the surface and contacting water, which results in substantial spreading of the contacting liquids on the surface. Due to their strong affinity, a high solid-liquid adhesion having virtually no mobility of the water on the surface occurs. However, counter-intuitively, the disclosed surfaces are highly slippery such that liquids can slide on the surface while maintaining their hydrophilicity. Demonstrated herein are water droplets that can slide on the surface under its own weight, when the hydrophilic, yet slippery solid surface is slightly tilted (ω=3°). This indicates that the disclosed hydrophilic surfaces are slippery to water.
FILED	Friday, January 11, 2019
APPL NO	16/246136
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/08 (20130101) A61L 33/00 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/18 (20130101) B05D 3/10 (20130101) B05D 5/08 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/30 (20130101) B32B 27/08 (20130101) Original (OR) Class B32B 27/28 (20130101) B32B 27/283 (20130101) B32B 27/285 (20130101) B32B 2307/728 (20130101) B32B 2307/746 (20130101) B32B 2535/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/336 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) C08L 71/08 (20130101) C08L 83/04 (20130101) C08L 2203/02 (20130101)
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10442182 — In vivo live 3D printing of regenerative bone healing scaffolds for rapid fracture healing

US 10442182	Varanasi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	The Texas A and M University System (College Station, Texas); The Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	The Texas A and M University System (College Station, Texas); The Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Venu G. Varanasi (Dallas, Texas); Azhar Ilyas (Arlington, Texas); Philip Roger Kramer (Dallas, Texas); Taha Azimaie (Dallas, Texas); Pranesh B. Aswath (Grapevine, Texas); Tugba Cebe (Grapevine, Texas)
ABSTRACT	Bio-Inks and methods of using compositions comprising the bio-Inks are disclosed. 3-D tissue repair and regeneration through precise and specific formation of biodegradable tissue scaffolds in a tissue site using the bio-inks are also provided. Specific methylacrylated gelatin hydrogels (MAC) and methacrylated chitosan (MACh) preparations formulated with sucrose, a silicate-containing component (such as laponite), and/or a cross-linking agent (such as a photo-initiator or chemical initiator), as well as powdered preparations of these, are also disclosed. Kits containing these preparations are provided for point-of-care tissue repair in vivo. Superior, more complete (up to 99.85% tissue regeneration within 4 weeks applied in situ), and rapid in situ tissue repair and bone formation are also demonstrated.
FILED	Wednesday, November 23, 2016
APPL NO	15/360788
ART UNIT	3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/722 (20130101) A61K 33/00 (20130101) A61K 38/39 (20130101) A61K 41/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0661 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/046 (20130101) B29K 2995/0056 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Original (OR) Class B33Y 80/00 (20141201)
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10442763 — EBNA1 inhibitors and methods using same

US 10442763	Messick et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia, Pennsylvania)
ASSIGNEE(S)	THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia, Pennsylvania)
INVENTOR(S)	Troy E. Messick (Upper Darby, Pennsylvania); Garry R. Smith (King of Prussia, Pennsylvania); Allen B. Reitz (Lansdale, Pennsylvania); Paul M. Lieberman (Wynnewood, Pennsylvania); Mark E. McDonnell (Lansdale, Pennsylvania); Yan Zhang (Fort Washington, Pennsylvania); Marianne Carlsen (Yardley, Pennsylvania); Shuai Chen (Philadelphia, Pennsylvania)
ABSTRACT	The present invention provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by EBNA1 activity, such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The present invention further provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection and/or lytic EBV infection.
FILED	Saturday, May 14, 2016
APPL NO	15/571223
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/41 (20130101) A61K 31/404 (20130101) A61K 31/422 (20130101) A61K 31/426 (20130101) A61K 31/427 (20130101) A61K 31/433 (20130101) A61K 31/435 (20130101) A61K 31/437 (20130101) A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/501 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/541 (20130101) A61K 31/551 (20130101) A61K 31/4155 (20130101) A61K 31/4375 (20130101) A61K 31/4439 (20130101) A61K 31/4725 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 209/08 (20130101) Original (OR) Class C07D 277/62 (20130101) C07D 401/10 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/10 (20130101) C07D 403/12 (20130101) C07D 403/14 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 409/12 (20130101) C07D 413/10 (20130101) C07D 417/10 (20130101) C07D 417/12 (20130101) C07D 471/04 (20130101) C07D 471/08 (20130101) C07D 471/10 (20130101) C07D 487/04 (20130101) C07D 487/08 (20130101) C07D 491/107 (20130101)
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10442806 — Substituted heterocycles for targeting HSP90

US 10442806	Haystead et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Duke University (Durham, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Timothy Haystead (Chapel Hill, North Carolina); Philip Floyd Hughes (Chapel Hill, North Carolina); Christopher D. Lascola (Durham, North Carolina)
ABSTRACT	Described herein are substituted indazoles comprising formula (II) that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. Formula (II) may link to detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.
FILED	Tuesday, June 05, 2018
APPL NO	16/000077
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 231/54 (20130101) C07D 405/14 (20130101) C07D 413/12 (20130101) C07D 473/24 (20130101) C07D 473/34 (20130101) Original (OR) Class C07D 487/04 (20130101) C07D 493/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/56988 (20130101) G01N 33/57496 (20130101) G01N 2333/47 (20130101)
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10442817 — Inhibitors of RAD52 recombination protein and methods using same

US 10442817	Mazin
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Mental Health (NIMH)
APPLICANT(S)	Alexander V. Mazin (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S)	Alexander V. Mazin (Philadelphia, Pennsylvania)
ABSTRACT	The present invention includes novel RAD52 inhibitors for preventing or treating cancers in a subject in need thereof. The present invention further includes a method of preventing or treating cancers in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound of the invention. In certain embodiments, the subject is further administered at least one additional therapeutic agent.
FILED	Friday, June 03, 2016
APPL NO	15/578558
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/47 (20130101) A61K 31/55 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 31/4188 (20130101) A61K 31/4188 (20130101) A61K 31/4525 (20130101) A61K 31/4741 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 215/38 (20130101) C07D 239/95 (20130101) C07D 307/82 (20130101) C07D 405/12 (20130101) C07D 471/04 (20130101) C07D 491/048 (20130101) C07D 491/056 (20130101) C07D 495/04 (20130101) Original (OR) Class
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10442839 — Monomeric near-infrared fluorescent proteins engineered from bacterial phytochromes and methods for making same

US 10442839	Verkhusha et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York)
ASSIGNEE(S)	Albert Einstein College of Medicine (Bronx, New York)
INVENTOR(S)	Vladislav V. Verkhusha (Bronx, New York); Daria M. Shcherbakova (Bronx, New York); Mikhail Baloban (Saint-Léonard, Canada)
ABSTRACT	Nucleic acid molecules encoding monomeric near-infrared fluorescent proteins, variants and derivatives thereof are provided, as well as proteins and peptides encoded by these nucleic acids. Also provided are proteins that are substantially similar to, or derivatives, homologues, or mutants of, the above-referenced specific proteins. Also provided are fragments of the nucleic acids and the peptides encoded thereby, specifically split fluorescent proteins. In addition, host-cells, stable cell lines and transgenic organisms comprising above-referenced nucleic acid molecules are provided. The invention also refers to methods of making and using monomeric fluorescent proteins derived from bacterial phytochromes. The subject protein and nucleic acid compositions find use in a variety of different applications and methods, particularly for labeling of biomolecules, cells or cell organelles, and for detecting protein-protein interactions. Finally, kits for use in such methods and applications are provided.
FILED	Wednesday, April 26, 2017
APPL NO	15/497667
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 14/195 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/50 (20130101) C07K 2319/60 (20130101)
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10442853 — Antibodies and processes for preparing the same

US 10442853	Refaeli et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Taiga Biotechnologies, Inc. (Aurora, Colorado)
ASSIGNEE(S)	TAIGA BIOTECHNOLOGIES, INC. (Aurora, Colorado)
INVENTOR(S)	Yosef Refaeli (Denver, Colorado); Brian Turner (Denver, Colorado)
ABSTRACT	Provided herein are various processes for the improved production of antibody producing organisms, antibody producing tissues, antibody producing cells and antibodies. In certain embodiments, provided herein are methods for rapidly producing antibody producing organisms, tissues, cells and antibodies derived from humans, organisms, plants or cells that are genetically altered to over-express certain proteins.
FILED	Tuesday, August 23, 2016
APPL NO	15/244138
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 2039/53 (20130101) A61K 2039/505 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/82 (20130101) Original (OR) Class C07K 16/00 (20130101) C07K 16/40 (20130101) C07K 16/1018 (20130101) C07K 2319/10 (20130101) C07K 2319/20 (20130101) C07K 2319/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101)
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10443039 — Inhibition of dendritic cell-driven regulatory T cell activation and potentiation of tumor antigen-specific T cell responses by interleukin-15 and MAP kinase inhibitor

US 10443039	Cannon et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Board of Trustees of the University of Arkansas (Little Rock, Arkansas)
ASSIGNEE(S)	Bioventures, LLC (Little Rock, Arkansas)
INVENTOR(S)	Martin J. Cannon (Little Rock, Arkansas); Kellie Kozak Vaidya (Fort Worth, Texas); Timothy J. O'Brien (Little Rock, Arkansas)
ABSTRACT	The invention involves the discovery that if dendritic cells loaded with a tumor antigen are cultured in interleukin-15 (IL-15), or if T cells activated by the dendritic cells are cultured in IL-15, Treg activity that is specific for the tumor antigen is reduced. This reduction in Treg activity results in an increase in anti-tumor immune response. Another embodiment of the invention involves the discovery that incubating dendritic cells with a MAP kinase inhibitor in combination with IL-15 gives synergistic benefits when the dendritic cells are used to activate T cells. Dendritic cell and T cell compositions incubated with IL-15 or a MAP kinase inhibitor are provided.
FILED	Monday, September 30, 2013
APPL NO	14/040850
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/2086 (20130101) A61K 38/2086 (20130101) A61K 39/0011 (20130101) A61K 2039/57 (20130101) A61K 2039/5154 (20130101) A61K 2039/5158 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 5/0639 (20130101) C12N 2501/02 (20130101) C12N 2501/22 (20130101) C12N 2501/23 (20130101) C12N 2501/25 (20130101)
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10443043 — Methods for making induced pluripotent stem cells

US 10443043	Stadtfeld et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Matthias Stadtfeld (New York, New York); Simon E. Vidal (New York, New York); Bhishma Amlani (New York, New York)
ASSIGNEE(S)	NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S)	Matthias Stadtfeld (New York, New York); Simon E. Vidal (New York, New York); Bhishma Amlani (New York, New York)
ABSTRACT	In vitro methods for generating induced pluripotent cells (iPSCs) are disclosed herein. Also encompassed are recombinant iPSCs generated using these methods and methods of use thereof.
FILED	Friday, May 06, 2016
APPL NO	15/148230
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) Original (OR) Class C12N 2501/15 (20130101) C12N 2501/415 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/606 (20130101) C12N 2506/1307 (20130101)
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10443049 — Active low molecular weight variants of angiotensin converting enzyme 2 (ACE2)

US 10443049	Batlle et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Daniel Batlle (Chicago, Illinois); Jan Wysocki (Chicago, Illinois)
ABSTRACT	Disclosed are variants of ACE2, pharmaceutical compositions comprising the variants of ACE2, and treatment methods for reducing Angiotensin II (1-8) plasma levels and/or increasing Angiotensin (1-7) plasma levels in a subject in need thereof. The disclosed variants of ACE2 may include polypeptide fragments of ACE2 having ACE2 activity for converting AngII(1-8) to Ang(1-7). Suitable subjects suitable for the disclosed methods of treatment may include subjects having or at risk for developing diabetic and non-diabetic chronic kidney disease, acute renal failure and its prevention, chronic kidney disease, severe hypertension, scleroderma and its skin, pulmonary, kidney and hypertensive complications, malignant hypertension, renovascular hypertension secondary to renal artery stenosis, idiopathic pulmonary fibrosis, liver fibrosis such as in liver cirrhosis patients, an aortic aneurysm, cardiac fibrosis and remodeling, left ventricular hypertrophy, and an acute stroke.
FILED	Wednesday, January 24, 2018
APPL NO	15/878823
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/4813 (20130101) A61K 47/60 (20170801) A61K 47/68 (20170801) A61K 47/6929 (20170801) Peptides C07K 14/315 (20130101) C07K 14/765 (20130101) C07K 2319/21 (20130101) C07K 2319/30 (20130101) C07K 2319/31 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) Original (OR) Class Enzymes C12Y 304/17023 (20130101)
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10443050 — Sample processing methods

US 10443050	Chen et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Roche Molecular Systems, Inc. (Pleasanton, California)
ASSIGNEE(S)	Roche Molecular Systems, Inc. (Pleasanton, California)
INVENTOR(S)	Shuqi Chen (Framingham, Massachusetts); Lingjun Chen (Framingham, Massachusetts)
ABSTRACT	A method of processing a sample may include introducing a sample into a vessel, the vessel having proximal and distal ends, the sample being introduced into the proximal end of the vessel; incubating the sample in the vessel with a substance capable of specific binding to a preselected component of the sample; propelling components of the incubated sample, other than the preselected component, toward the proximal end of the vessel by clamping the vessel distal to the incubated sample and compressing the vessel where the incubated sample is contained; propelling the preselected component toward a distal segment of the vessel by clamping the vessel proximal to the preselected component and compressing the vessel where the preselected component is contained; and mixing the preselected component with a reagent in the distal segment of the vessel.
FILED	Thursday, June 15, 2017
APPL NO	15/624535
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/505 (20130101) B01L 2200/10 (20130101) B01L 2200/0621 (20130101) B01L 2300/10 (20130101) B01L 2300/042 (20130101) B01L 2300/046 (20130101) B01L 2300/047 (20130101) B01L 2300/069 (20130101) B01L 2300/087 (20130101) B01L 2300/0681 (20130101) B01L 2400/0481 (20130101) B01L 2400/0677 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1003 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 33/543 (20130101) Technologies for Adaptation to Climate Change Y02A 50/52 (20180101) Y02A 50/53 (20180101) Y02A 50/58 (20180101) Y02A 50/60 (20180101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 435/81 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/25 (20150115)
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10443054 — Methods for identifying and treating invasive/metastatic breast cancers

US 10443054	Gertler et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); King's College London (London, United Kingdom)
ASSIGNEE(S)	MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); KING'S COLLEGE LONDON (London, England, United Kingdom)
INVENTOR(S)	Frank B. Gertler (Boston, Massachusetts); Guillaume Carmona (Boston, Massachusetts); Matthias Krause (London, United Kingdom); Upamali Perera (London, United Kingdom)
ABSTRACT	Cancer invasion is a hallmark of metastasis. The mesenchymal mode of cancer cell invasion is mediated by elongated membrane protrusions driven by the assembly of branched F-actin networks. Described herein are compositions and methods for assessing and treating a subject having metastatic cancer or at risk of developing metastatic cancer, e.g., metastatic breast cancer, through the determination of Lamellipodin protein or gene expression levels in the subject.
FILED	Monday, March 06, 2017
APPL NO	15/451374
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/315 (20130101) C12N 2310/531 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 2030/8813 (20130101)
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10443055 — Compounds that target MYC microRNA responsive elements for the treatment of MYC-associated cancer

US 10443055	Pandolfi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	BETH ISRAEL DEACONESS MEDICAL CENTER (Boston, Massachusetts)
ASSIGNEE(S)	BETH ISRAEL DEACONESS MEDICAL CENTER (Boston, Massachusetts)
INVENTOR(S)	Pier Paolo Pandolfi (Boston, Massachusetts); Assaf C. Bester (Boston, Massachusetts); Yvonne Tay (Singapore, Singapore)
ABSTRACT	Novel mIR-330 agents and their methods of use are provided. Methods of treating MYC-associated cancers are provided.
FILED	Monday, December 18, 2017
APPL NO	15/845573
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/1135 (20130101) C12N 2310/141 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/3521 (20130101) C12N 2750/14143 (20130101)
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10443075 — Adeno-associated virus vector variants for high efficiency genome editing and methods thereof

US 10443075	Chatterjee et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	CITY OF HOPE (Duarte, California)
ASSIGNEE(S)	CITY OF HOPE (Duarte, California)
INVENTOR(S)	Saswati Chatterjee (Altadena, California); Laura Jane Smith (Westford, Massachusetts); Kamehameha Wong (Altadena, California)
ABSTRACT	Adeno-associated virus (AAV) Clade F vectors or AAV vector variants (relative to AAV9) for precise editing of the genome of a cell and methods and kits thereof are provided. Targeted genome editing using the AAV Clade F vectors or AAV vector variants provided herein occurred at frequencies that were shown to be 1,000 to 100,000 fold more efficient than has previously been reported. Also provided are methods of treating a disease or disorder in a subject by editing the genome of a cell of the subject via transducing the cell with an AAV Clade F vector or AAV vector variant as described herein and further transplanting the transduced cell into the subject to treat the disease or disorder of the subject. Also provided herein are methods of treating a disease or disorder in a subject by in vivo genome editing by directly administering the AAV Clade F vector or AAV vector variant as described herein to the subject.
FILED	Monday, February 12, 2018
APPL NO	15/894538
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 48/005 (20130101) A61K 48/0008 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2710/16622 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) C12N 2750/14152 (20130101) C12N 2750/14171 (20130101) C12N 2800/70 (20130101) C12N 2840/44 (20130101)
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10443091 — Selective oxidation of 5-methylcytosine by TET-family proteins

US 10443091	Rao et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S)	CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
INVENTOR(S)	Anjana Rao (La Jolla, California); Mamta Tahiliani (New York, New York); Kian Peng Koh (Jamaica Plain, Massachusetts); Suneet Agarwal (Belmont, Massachusetts); Aravind Iyer (Bethesda, Maryland)
ABSTRACT	The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes being capable of converting the cytosine nucleotide 5-methylcytosine into 5-hydroxymethylcytosine by hydroxylation.
FILED	Monday, June 27, 2016
APPL NO	15/193796
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0607 (20130101) C12N 5/0637 (20130101) C12N 5/0696 (20130101) C12N 9/0071 (20130101) C12N 15/873 (20130101) C12N 2501/15 (20130101) C12N 2501/70 (20130101) C12N 2501/71 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/606 (20130101) C12N 2501/999 (20130101) C12N 2506/1307 (20130101) C12N 2506/1353 (20130101) C12N 2510/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6869 (20130101) C12Q 1/6886 (20130101) C12Q 2521/531 (20130101) C12Q 2521/531 (20130101) C12Q 2522/10 (20130101) C12Q 2522/10 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101) C12Q 2600/154 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5308 (20130101) G01N 33/57426 (20130101) G01N 33/57484 (20130101) G01N 33/57496 (20130101) G01N 2500/00 (20130101)
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10443092 — Methods of elongating DNA

US 10443092	Wu
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Chao-ting Wu (Brookline, Massachusetts)
ABSTRACT	The present invention relates to methods of elongating chromosomes. Embodiments of the present disclosure are directed to methods of elongating DNA by immobilizing or attaching the DNA to a substrate. According to one aspect, naturally occurring DNA includes a nucleic acid and one or more factors bound thereto, and may be referred to herein as “starting DNA”.
FILED	Tuesday, March 11, 2014
APPL NO	14/774291
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6834 (20130101) Original (OR) Class C12Q 1/6834 (20130101) C12Q 1/6841 (20130101) C12Q 1/6841 (20130101) C12Q 2521/537 (20130101) C12Q 2521/537 (20130101) C12Q 2523/307 (20130101) C12Q 2523/307 (20130101) C12Q 2543/10 (20130101) C12Q 2543/10 (20130101) C12Q 2565/518 (20130101) C12Q 2565/518 (20130101)
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10443100 — Gene expression profiles associated with sub-clinical kidney transplant rejection

US 10443100	Salomon et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California); NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S)	The Scripps Research Institute (La Jolla, California)
INVENTOR(S)	Daniel R. Salomon (San Diego, California); John Friedewald (Chicago, Illinois); Sunil Kurian (San Diego, California); Michael M. Abecassis (Highland Park, Illinois); Steve Head (Lakeside, California); Phillip Ordoukhanian (San Diego, California)
ABSTRACT	By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.
FILED	Tuesday, November 22, 2016
APPL NO	15/358390
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2537/165 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 25/10 (20190201) G16B 40/20 (20190201) G16B 40/30 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/30 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101)
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10443101 — Exonic splicing enhancers and exonic splicing silencers

US 10443101	Sanford et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Jeremy Sanford (Santa Cruz, California); Timothy Steme-Weiler (Santa Cruz, California)
ABSTRACT	Compounds and methods for regulation of exonic splicing enhancers and exonic splicing silencers. Compounds include polynucleotides targeted to aberrant exonic splicing enhancers and exonic splicing silencers. Compounds and methods for the diagnosis of diseases and conditions associated with aberrant exonic splicing enhancers and exonic splicing silencers. Methods for identifying splicing-sensitive disease mutations, and functional RNA elements as targets for amelioration of aberrant pre-mRNA splicing.
FILED	Friday, September 15, 2017
APPL NO	15/706485
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2320/33 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class
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10443105 — Methods and compositions for correlating genetic markers with prostate cancer risk

US 10443105	Xu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
ASSIGNEE(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S)	Jianfeng Xu (Clemmons, North Carolina); Siqun Lilly Zheng (Clemmons, North Carolina); Jielin Sun (Oak Ridge, North Carolina); Andrew Karim Kader (San Diego, California)
ABSTRACT	The present invention provides methods of assessing an individual subject's risk of developing prostate cancer, comprising: a) analyzing a nucleic acid sample obtained from the subject and determining a genotype for the subject at a plurality of biallelic polymorphic loci, wherein each of said plurality has an associated allele and an unassociated allele, wherein the genotype is selected from the group consisting of homozygous for the associated allele, heterozygous, and homozygous for the unassociated allele; and b) calculating a cumulative relative risk (CRR) for the subject based on the genotype determined in step (a). A CRR of greater than 1.00 identifies a subject as having an increased risk of developing prostate cancer and also can identify a subject who is a candidate for early PSA screening, prostate biopsy and/or chemoprevention.
FILED	Friday, August 11, 2017
APPL NO	15/675273
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/172 (20130101)
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10444123 — Volatile organic compounds (VOCs) for the diagnosis of Clostridium difficile-associated diarrhea (CDAD)

US 10444123	Koo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The Brigham and Women s Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Sophia Koo (Brookline, Massachusetts); Lindsey Robert Baden (Brookline, Massachusetts); Francisco M. Marty (Chestnut Hill, Massachusetts)
ABSTRACT	Methods for diagnosing, treating, and monitoring the treatment of Clostridium difficile infections (CDI), e.g., Clostridium difficile-Associated Diarrhea (CDAD). The methods can include detecting the presence of one or more volatile organic compounds (VOCs) in a sample from ambient air or stool sample from subjects suspected of having a CDI, e.g., CDAD.
FILED	Monday, August 03, 2015
APPL NO	15/500377
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/22 (20130101) G01N 1/2214 (20130101) Original (OR) Class G01N 33/497 (20130101) G01N 2033/4975 (20130101) G01N 2333/33 (20130101)
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10444136 — Particle emission tomography

US 10444136	Barrett et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); inviCro, LLC (Boston, Massachusetts)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); InviCro, LLC (Boston, Massachusetts)
INVENTOR(S)	Harrison H. Barrett (Tucson, Arizona); Yijun Ding (Tucson, Arizona); Luca Caucci (Tucson, Arizona); John William Hoppin (Boston, Massachusetts)
ABSTRACT	The present invention provides autoradiography methods and systems for imaging via the detection of alpha particles, beta particles, or other charged particles. Embodiments of the methods and systems provide high-resolution 3D imaging of the distribution of a radioactive probe, such as a radiopharmaceutical, on a tissue sample. Embodiments of the present methods and systems provide imaging of tissue samples by reconstruction of a 3D distribution of a source of particles, such as a radiopharmaceutical. Embodiments of the methods and systems provide tomographic methods including microtomography, macrotomography, cryomicrotomography and cryomacrotomography.
FILED	Wednesday, November 11, 2015
APPL NO	15/526514
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 6/037 (20130101) A61B 6/4241 (20130101) A61B 6/4258 (20130101) A61B 6/5205 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/004 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/02 (20130101) G01N 15/0227 (20130101) Original (OR) Class Measurement of Nuclear or X-radiation G01T 1/2942 (20130101)
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10444220 — Controlled tunnel gap device for sequencing polymers

US 10444220	Lindsay et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Stuart Lindsay (Phoenix, Arizona); Shuai Chang (Tempe, Arizona); Jin He (Mesa, Arizona); Peiming Zhang (Gilbert, Arizona); Shuo Huang (Tempe, Arizona)
ABSTRACT	The invention includes compositions, devices, and methods for analyzing a polymer and/or polymer unit. The polymer may be a homo or hetero-polymer such as DNA, RNA, a polysaccharide, or a peptide. The device includes electrodes that form a tunnel gap through which the polymer can pass. The electrodes are functionalized with a reagent attached thereto, and the reagent is capable of forming a transient bond to a polymer unit. When the transient bond forms between the reagent and the unit, a detectable signal is generated and used to analyze the polymer.
FILED	Friday, September 22, 2017
APPL NO	15/712552
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3275 (20130101) G01N 33/48721 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115)
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10444223 — Integrated organ-on-chip systems and applications of the same

US 10444223	Wikswo et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Defense Threat Reduction Agency (DTRA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) National Cancer Institute (NCI) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	John P. Wikswo (Brentwood, Tennessee); David E. Cliffel (Nashville, Tennessee); Dmitry A. Markov (Nashville, Tennessee); John A. McLean (Nashville, Tennessee); Lisa Joy McCawley (Nashville, Tennessee); Phillip C. Samson (Nashville, Tennessee); Ronald S. Reiserer (Nashville, Tennessee); Frank Emmanuel Block (Nashville, Tennessee); Jennifer Robin McKenzie (Nashville, Tennessee)
ABSTRACT	A microclinical analyzer usable for analysis of one or more bio-objects, each bio-object including an organ or a group of cells includes a fluidic network having a plurality of fluidic switches, a plurality of fluidic paths in fluid communication with the plurality of fluidic switches, and one or more on-chip pumps coupled to corresponding fluidic paths; a sensor array coupled to the fluidic network; and a microcontroller for individually controlling the plurality of fluidic switches and the one or more on-chip pumps of the fluidic network as so to operably and selectively deliver an effluent of at least one bio-object to the sensor array for detecting properties of the effluent, or to a predetermined outlet destination.
FILED	Monday, July 30, 2018
APPL NO	16/049025
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0247 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502715 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0877 (20130101) B01L 2400/0481 (20130101) B01L 2400/0487 (20130101) B01L 2400/0622 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) Original (OR) Class G01N 35/1095 (20130101)
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10444224 — Method for RNA detection and quantification

US 10444224	Jaffrey et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Samie R. Jaffrey (New York, New York); Jeremy Paige (La Jolla, California)
ABSTRACT	The present invention relates to novel nucleic acid molecules, called aptamers, that bind specifically to a small molecule fluorophore and thereby enhance the fluorescence signal of the fluorophore upon exposure to radiation of suitable wavelength. Molecular complexes formed between the novel fluorophores, novel nucleic acid molecules, and their target molecules are described, and the use of multivalent aptamer constructs as fluorescent sensors for target molecules of interest are also described.
FILED	Tuesday, February 26, 2019
APPL NO	16/286376
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 233/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/5008 (20130101) Original (OR) Class
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10444233 — Selective capture and stimulated release of circulating tumor cells on nanostructured devices

US 10444233	Tseng et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California); RIKEN (Saitama, Japan)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); Riken (Saitama, Japan)
INVENTOR(S)	Hsian-Rong Tseng (Los Angeles, California); Shuang Hou (Los Angeles, California); Libo Zhao (Los Angeles, California); Hsiao-Hua Yu (Saitama, Japan); Shyh-Chyang Luo (Saitama, Japan); Haichao Zhao (Saitama, Japan)
ABSTRACT	A device for capturing preselected cell types from a fluid sample that includes a plurality of cell types includes a substrate, a plurality of nanowires at least one of attached to or integral with a surface of the substrate such that each nanowire of the plurality of nanowires has an unattached end, and a layer of temperature-responsive material formed on at least the unattached end of each of the plurality of nanowires. The layer of temperature-responsive material has a compact configuration at a first temperature and an expanded configuration at a second temperature so as to facilitate release of cells captured at the first temperature to be released at the second temperature.
FILED	Wednesday, July 31, 2013
APPL NO	14/418406
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/545 (20130101) Original (OR) Class G01N 33/54306 (20130101) G01N 33/54346 (20130101) G01N 2333/70596 (20130101)
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10445880 — Molecular imaging biomarkers

US 10445880	Boppart et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Stephen A. Boppart (Champaign, Illinois); Haohua Tu (Savoy, Illinois); Sixian You (Urbana, Illinois); Yuan Liu (Dublin, California)
ABSTRACT	Methods for label-free characterization of untagged molecules within a biological sample in-situ. The untagged molecules may be constituent of extracellular vesicles, and are excited in the biological sample with at least one wavelength band of light derived from a single stream of optical pulses. Light emitted by the untagged molecules by SHG, THG, 2PAF and 3PAF processes is detected. Separate measures of the biological sample corresponding to light emitted by the untagged molecules in each of the SHG, THG, 2PAF and 3PAF processes are derived. On that basis, normal extracellular vesicles may be differentiated from extracellular vesicles associated with a tumor on the basis of a specified signature of characteristics of images of SHG, THG, 2PAF and 3PAF processes.
FILED	Thursday, March 22, 2018
APPL NO	15/928818
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1456 (20130101) G01N 21/65 (20130101) G01N 21/636 (20130101) G01N 21/6486 (20130101) G01N 33/483 (20130101) G01N 2015/144 (20130101) G01N 2015/1006 (20130101) G01N 2021/653 (20130101) G01N 2201/06113 (20130101) Image Data Processing or Generation, in General G06T 7/0014 (20130101) Original (OR) Class G06T 2207/10064 (20130101) G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) G06T 2207/30096 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/00 (20190201)
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10446259 — Systems, apparatus, and methods for analyzing and predicting cellular pathways

US 10446259	Pirhaji et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of General Medical Sciences (NIGMS) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Leila Pirhaji (Cambridge, Massachusetts); Ernest Fraenkel (Newton, Massachusetts)
ABSTRACT	Integrative analysis of metabolites is essential to obtain a comprehensive view of dysregulated biological pathways leading to a disease. Despite the great potential of metabolites their system level analysis has been limited. Global measurements of the metabolites by liquid chromatography-mass spectrometry (MS) detects metabolites features changing in a disease. However, identification of each feature is a bottleneck in metabolomics, in which a fraction of them are identified via tandem MS. Consequently, the scarcity of these data add additional barriers to decipher their biological meaning, especially in relation to other 'omic data such as proteomics. To address these challenges, a novel network-based approach called PIUMet is described. PIUMet infers dysregulated pathways and components from the differential metabolite features between control and disease systems without the need for the prior identification. The application of PIUMet is demonstrated by integrative analysis of untargeted lipid profiling data of a cell line model of Huntington's disease. The results show that PIUMet inferred dysregulation of sphingolipid metabolism in the disease cells. Additionally, PIUMet identified disease-modifying metabolite in the pathway that remained undetected experimentally. Furthermore, the lipidomic data of these cell lines was integrated with global phospho-proteomic ones. Integrative analysis of these data using PIUMet was shown to systematically lead to identifying dysregulated proteins in the disease cells that cannot be distinguished with individual analysis of each dataset.
FILED	Wednesday, August 10, 2016
APPL NO	15/233246
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5038 (20130101) G01N 33/6848 (20130101) G01N 33/6896 (20130101) G01N 2800/2835 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class G16B 20/00 (20190201)
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10447318 — Low power high gain radio frequency amplifier for sensor apparatus

US 10447318	Blaauw et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	The Regents of The University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	David T. Blaauw (Ann Arbor, Michigan); David D. Wentzloff (Ann Arbor, Michigan); Li-Xuan Chuo (Ann Arbor, Michigan); Hun-Seok Kim (Ann Arbor, Michigan)
ABSTRACT	A wireless communication device is presented for use with a sensor. The wireless communication device includes: an antenna, a driver circuit and a bias circuit. The driver circuit is electrically coupled to the antenna and includes at least one pair of cross-coupled transistors. The bias circuit is electrically coupled to the driver circuit. In a transmit mode, the bias circuit biases the driver circuit with a first bias current. In response to the first bias current, the driver circuit oscillates the antenna. In a receive mode, the bias circuit biases the driver circuit with a second bias current, such that the first bias current differs from the second bias current. In response to the second bias current, the bias circuit amplifies a signal received by the antenna.
FILED	Friday, February 02, 2018
APPL NO	15/887212
ART UNIT	2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 7/00 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/1212 (20130101) H03B 5/1228 (20130101) H03B 2200/0008 (20130101) H03B 2200/0082 (20130101) Transmission H04B 1/04 (20130101) Original (OR) Class H04B 1/40 (20130101)
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Department of Energy (DOE)

10441185 — Flexible and stretchable electronic systems for epidermal electronics

US 10441185	Rogers et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Neurological Disorders and Stroke (NINDS) Tissue Engineering Resource Center (TERC) National Science Foundation (NSF)
APPLICANT(S)	John A. Rogers (Champaign, Illinois); Dae-Hyeong Kim (Champaign, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	John A. Rogers (Champaign, Illinois); Dae-Hyeong Kim (Champaign, Illinois)
ABSTRACT	Provided herein are skin-mounted biomedical devices and methods of making and using biomedical devices for sensing and actuation applications. For example, flexible and/or stretchable biomedical devices are provided, including electronic devices useful for establishing conformal contact with the skin of a subject. Devices disclosed herein can comprise a plurality of sensing and/or actuating devices provided as part of a skin-mounted flexible or stretchable electronic circuit.
FILED	Friday, June 08, 2012
APPL NO	13/492636
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/076 (20130101) A61B 5/0422 (20130101) A61B 5/0478 (20130101) A61B 5/0492 (20130101) A61B 5/0537 (20130101) A61B 5/1104 (20130101) A61B 5/1107 (20130101) A61B 5/04085 (20130101) Original (OR) Class A61B 5/04284 (20130101) A61B 5/4875 (20130101) A61B 5/6867 (20130101) A61B 2562/02 (20130101) A61B 2562/12 (20130101) A61B 2562/029 (20130101) A61B 2562/046 (20130101) A61B 2562/066 (20130101) A61B 2562/164 (20130101) A61B 2562/0261 (20130101) A61B 2562/0271 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/36 (20130101) A61N 1/0472 (20130101) A61N 1/0587 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/3121 (20130101) H01L 23/3192 (20130101) H01L 27/1218 (20130101) H01L 29/7869 (20130101) H01L 29/78603 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2924/3011 (20130101) H01L 2924/3025 (20130101) H01L 2924/12044 (20130101) H01L 2924/19041 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/147 (20130101) H05K 1/189 (20130101) H05K 1/0283 (20130101) H05K 3/323 (20130101) H05K 2201/09263 (20130101)
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10441922 — Dual function composite oxygen transport membrane

US 10441922	Lin et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Jiefeng Lin (Rochester, New York); Pawel Plonczak (Buffalo, New York); Sean M. Kelly (Pittsford, New York); Uttam R. Doraswami (Bangalore, India); Jonathan A. Lane (Snyder, New York)
ASSIGNEE(S)	PRAXAIR TECHNOLOGY, INC. (Danbury, Connecticut)
INVENTOR(S)	Jiefeng Lin (Rochester, New York); Pawel Plonczak (Buffalo, New York); Sean M. Kelly (Pittsford, New York); Uttam R. Doraswami (Bangalore, India); Jonathan A. Lane (Snyder, New York)
ABSTRACT	A dual function composite oxygen transport membrane having a layered structure of mixed conducting oxygen transport materials on a first side of a porous substrate and a reforming catalyst layer on an opposing second side of the porous substrate. The layered structure of the mixed conducting oxygen transport materials contains an intermediate porous layer of mixed conducting oxygen transport materials formed on the porous substrate with a dense impervious layer of mixed conducting oxygen transport materials over the intermediate porous layer, and an optional surface exchange layer of mixed conducting oxygen transport materials over the dense impervious layer. The layered structure and the reforming catalyst layer are formed in separate steps.
FILED	Monday, June 29, 2015
APPL NO	14/753815
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Separation B01D 53/228 (20130101) B01D 67/0039 (20130101) B01D 67/0048 (20130101) B01D 69/04 (20130101) B01D 69/10 (20130101) B01D 69/12 (20130101) B01D 71/022 (20130101) Original (OR) Class B01D 71/024 (20130101) B01D 2311/2696 (20130101) B01D 2325/10 (20130101) B01D 2325/20 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/462 (20130101) B01J 23/892 (20130101) B01J 35/065 (20130101)
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10441940 — Polymers grafted with organic phosphorous compounds for extracting uranium from solutions

US 10441940	Tissot et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)	UNIVERSITY OF MARYLAND (College Park, Maryland); THE CATHOLIC UNIVERSITY OF AMERICA (Washington, District of Columbia)
ASSIGNEE(S)	UNIVERSITY OF MARYLAND, College Park (College Park, Maryland); CATHOLIC UNIVERSITY OF AMERICA (Washington, District of Columbia)
INVENTOR(S)	Chanel Tissot (Hyattsville, Maryland); Aaron Barkatt (Silver Spring, Maryland); Mohamad I. Al-Sheikhly (Potomac, Maryland)
ABSTRACT	Complexing or chelating agents that offer strong, selective bonding with uranium as well as a broad pH range of effectiveness, specifically including the pH range around 8.2, together with the acrylic double bonds required for radiation-induced grafting on polymers to remove uranium from a solution such as seawater. The novel adsorbing species are phosphorus-containing molecules, in particular organic phosphates, phosphonates and phosphoric acids. Organic phosphorus compounds, for example, organic phosphates, phosphonates, and phosphoric acids, are attached to polymer fibers to form fibers, fiber fabrics or membranes that are effective, or show activity, in uranium adsorption.
FILED	Tuesday, August 20, 2013
APPL NO	14/412892
ART UNIT	1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/264 (20130101) B01J 20/265 (20130101) B01J 20/321 (20130101) B01J 20/2804 (20130101) B01J 20/3085 (20130101) Original (OR) Class B01J 20/3212 (20130101) B01J 20/3278 (20130101) B01J 20/3425 (20130101) B01J 20/3475 (20130101) B01J 20/28023 (20130101) B01J 20/28038 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/285 (20130101) C02F 1/683 (20130101) C02F 2101/006 (20130101) C02F 2103/08 (20130101) C02F 2303/16 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/00 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 60/0265 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/12 (20130101)
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10442037 — Pb-free Sn—Ag—Cu—Al or Sn—Cu—Al solder

US 10442037	Anderson et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Ames Laboratory (AL) Federally Funded Research and Development Center (FFRDC) Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S)	Iver E. Anderson (Ames, Iowa); Joel L. Harringa (Ames, Iowa); Adam J. Boesenberg (Ankeny, Iowa)
ABSTRACT	A solder alloy includes Sn, optional Ag, Cu, and Al wherein the alloy composition is controlled to provide a strong, impact-and thermal aging-resistant solder joint that has beneficial microstructural features and is substantially devoid of Ag₃Sn blades.
FILED	Tuesday, February 24, 2015
APPL NO	14/544833
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 35/001 (20130101) B23K 35/0244 (20130101) B23K 35/262 (20130101) Original (OR) Class Alloys C22C 13/00 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/3463 (20130101)
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10442055 — Lubricated mechanical polishing

US 10442055	Cademartiri et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Ames Laboratory (AL) Federally Funded Research and Development Center (FFRDC) Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S)	Ludovico Cademartiri (Ames, Iowa); Briane Caroline Montoya (Denver, Colorado)
ABSTRACT	A lubricated mechanical polishing (LMP) process is provided that uses hard nanoparticles of less than 5 nm diameter dispersed in a fluid lubricant as a polishing slurry to produce an ultra-smooth surface on a hard metallic or non-metallic substrate with a sub-nanometer surface roughness substantially less than that produced by silica chemical mechanical polishing.
FILED	Tuesday, January 31, 2017
APPL NO	15/530575
ART UNIT	3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Machines, Devices, or Processes for Grinding or Polishing; Dressing or Conditioning of Abrading Surfaces; Feeding of Grinding, Polishing, or Lapping Agents B24B 37/044 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/1436 (20130101) C09K 3/1472 (20130101) Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 125/10 (20130101) C10M 2201/062 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2220/082 (20130101) C10N 2240/10 (20130101) C10N 2240/401 (20130101) C10N 2250/12 (20130101) C10N 2280/00 (20130101)
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10442120 — System for adjusting the equilibrium temperature of an inductively-heated susceptor

US 10442120	Matsen et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Marc R. Matsen (Seattle, Washington); Mark A. Negley (Bellevue, Washington); William Preston Geren (Shoreline, Washington)
ABSTRACT	A system for inductively heating a workpiece may include an induction coil, at least one susceptor face sheet, and a current controller coupled. The induction coil may be configured to conduct an alternating current and generate a magnetic field in response to the alternating current. The susceptor face sheet may be configured to have a workpiece positioned therewith. The susceptor face sheet may be formed of a ferromagnetic alloy having a Curie temperature and being inductively heatable to an equilibrium temperature approaching the Curie temperature in response to the magnetic field. The current controller may be coupled to the induction coil and may be configured to adjust the alternating current in a manner causing a change in at least one heating parameter of the susceptor face sheet.
FILED	Saturday, January 17, 2015
APPL NO	14/599475
ART UNIT	3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/06 (20130101) B29C 43/52 (20130101) Original (OR) Class B29C 2035/0811 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/105 (20130101) H05B 2206/023 (20130101)
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10442302 — Battery charging control methods, electrical vehicle charging methods, battery charging control apparatus, and electrical vehicles

US 10442302	Kintner-Meyer
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Michael Kintner-Meyer (Richland, Washington)
ABSTRACT	Battery charging control methods, electrical vehicle charging methods, battery charging control apparatus, and electrical vehicles are described. In one arrangement, battery charging control methods include accessing price information for electrical energy supplied by an electrical power distribution system and controlling an adjustment of an amount of the electrical energy from the electrical power distribution system used to charge a rechargeable battery at different moments in time using the price information. Other arrangements are described.
FILED	Wednesday, May 25, 2016
APPL NO	15/163925
ART UNIT	3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC	Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles B60H 1/00878 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 1/08 (20130101) B60L 11/184 (20130101) Original (OR) Class B60L 53/14 (20190201) B60L 53/60 (20190201) B60L 53/64 (20190201) B60L 53/65 (20190201) B60L 53/305 (20190201) B60L 58/12 (20190201) B60L 58/24 (20190201) B60L 2240/80 (20130101) Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 2510/244 (20130101) B60W 2510/246 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/007 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/705 (20130101) Y02T 10/6269 (20130101) Y02T 10/7005 (20130101) Y02T 10/7044 (20130101) Y02T 10/7088 (20130101) Y02T 90/14 (20130101) Y02T 90/121 (20130101) Y02T 90/128 (20130101) Y02T 90/163 (20130101) Y02T 90/169 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 30/14 (20130101)
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10442871 — Modified cyclodextrins for the selective sequestration of fentanyl related compounds and uses thereof

US 10442871	Kennedy et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Daniel Joseph Kennedy (Livermore, California); Brian P. Mayer (Livermore, California); Carlos A. Valdez (Livermore, California)
ABSTRACT	Novel thioalkylcarboxylate-modified CDs and pharmaceutical compositions comprising these thioalkylcarboxylate-modified CDs are disclosed, as well as methods of using the disclosed thioalkylcarboxylate-modified CDs and pharmaceutical compositions thereof to neutralize or reduce undesired effects or symptoms associated with one or more fentanyl related compounds in a subject in need thereof. The use of the disclosed thioalkylcarboxylate-modified CDs to detect the presence of one or more fentanyl related compounds in a sample is also disclosed, which comprises contacting the sample with said thioalkylcarboxylate-modified CDs or a composition comprising these CDs.
FILED	Thursday, June 22, 2017
APPL NO	15/630869
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/724 (20130101) Heterocyclic Compounds C07D 211/28 (20130101) C07D 221/00 (20130101) C07D 309/10 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0012 (20130101) Original (OR) Class
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10442887 — Functionalization of diels-alder polyphenylene polymers

US 10442887	Fujimoto
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Cy Fujimoto (Albuquerque, New Mexico)
ABSTRACT	The present invention relates to functionalized polymers including a poly(phenylene) structure. The structure can include any useful modifications, such as the inclusion of one or more reactive handles having an aryl group. Methods and uses of such structures and polymers are also described herein.
FILED	Wednesday, July 18, 2018
APPL NO	16/039153
ART UNIT	1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/10 (20130101) Original (OR) Class C08G 2261/11 (20130101) C08G 2261/46 (20130101) C08G 2261/72 (20130101) C08G 2261/146 (20130101) C08G 2261/148 (20130101) C08G 2261/312 (20130101) C08G 2261/516 (20130101) C08G 2261/722 (20130101) C08G 2261/728 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2287 (20130101) C08J 2365/02 (20130101) Compositions of Macromolecular Compounds C08L 65/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1023 (20130101) H01M 8/1039 (20130101)
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10442995 — Rapid production of hydrothermally carbonized biomass via reactive twin-screw extrusion

US 10442995	Felix et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Larry G. Felix (Pelham, Alabama); William E. Farthing (Pinson, Alabama); James H. Irvin (Hoover, Alabama); Todd R. Snyder (Birmingham, Alabama); Wei Yan (Memphis, Tennessee)
ASSIGNEE(S)	GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois)
INVENTOR(S)	Larry G. Felix (Pelham, Alabama); William E. Farthing (Pinson, Alabama); James H. Irvin (Hoover, Alabama); Todd R. Snyder (Birmingham, Alabama); Wei Yan (Memphis, Tennessee)
ABSTRACT	A system for the production of carbonized biomass that includes an infeed for accepting biomass feed material and an associated twin screw extruder. A water heater is connected with respect to at least one inlet along a length of the twin screw extruder and a pressure sustaining valve is connected at an outlet of the twin screw extruder.
FILED	Monday, March 17, 2014
APPL NO	14/216028
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/022 (20190201) B29C 48/67 (20190201) B29C 48/92 (20190201) B29C 48/268 (20190201) B29C 48/402 (20190201) B29C 48/832 (20190201) B29C 48/834 (20190201) B29C 2948/92704 (20190201) Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 7/10 (20130101) Original (OR) Class Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 9/086 (20130101)
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10443062 — Genes that improve tolerance to lignocellulosic toxins when overexpressed in yeast

US 10443062	Sardi et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S)	Maria Sardi (Madison, Wisconsin); Audrey P. Gasch (Madison, Wisconsin)
ABSTRACT	The present invention provides isolated gene sequences useful in increasing lignocellulosic toxin tolerance in yeast. Such engineered yeast are useful in methods of biofuel production, particularly ethanol production. Methods of bioengineering recombinant yeast with increased lignocellulosic toxin tolerance are also provided.
FILED	Friday, September 01, 2017
APPL NO	15/693710
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 14/395 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/1205 (20130101) C12N 15/52 (20130101) C12N 15/81 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 7/649 (20130101) Enzymes C12Y 101/0117 (20130101) C12Y 207/01025 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/13 (20130101) Y02E 50/16 (20130101) Y02E 50/343 (20130101)
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10443068 — Plants with engineered endogenous genes

US 10443068	Raab et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Agrivida, Inc. (Medford, Massachusetts)
ASSIGNEE(S)
INVENTOR(S)	R. Michael Raab (Arlington, Massachusetts); Michael Lanahan (Cary, North Carolina); Christopher Bonin (Colchester, Connecticut); Oleg Bougri (Boise, Idaho)
ABSTRACT	Genetically engineered plants expressing altered Glucan Water Dikinase and having elevated levels of starch are provided. Methods of genetically engineering plants to express altered Glucan Water Dikinase, and genetic constructs are provided. Methods of breeding genetically engineered plants homozygous for a mutated gene encoding an altered Glucan Water Dikinase are described. Methods of agricultural processing and animal feed using the genetically engineered plants are also provided.
FILED	Tuesday, January 31, 2017
APPL NO	15/420480
ART UNIT	1662 — Plants
CURRENT CPC	Fodder A23K 10/10 (20160501) A23K 10/30 (20160501) A23K 10/38 (20160501) A23K 40/10 (20160501) A23K 50/10 (20160501) A23K 50/30 (20160501) A23K 50/75 (20160501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1294 (20130101) C12N 15/8218 (20130101) C12N 15/8245 (20130101) Original (OR) Class C12N 15/8246 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/14 (20130101) Enzymes C12Y 207/00 (20130101) C12Y 207/09004 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 60/873 (20151101)
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10443410 — Ceramic matrix composite (CMC) hollow blade and method of forming CMC hollow blade

US 10443410	de Diego et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
ASSIGNEE(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S)	Peter de Diego (Saluda, North Carolina); Jacob John Kittleson (Greenville, South Carolina)
ABSTRACT	A ceramic matrix composite (CMC) hollow blade includes a CMC airfoil, which includes at least one airfoil CMC ply, at least one cavity CMC ply, and an insert. The airfoil CMC ply defines the contour of the CMC airfoil including a first edge, a second edge opposite the first edge, a first side extending from the first edge to the second edge, and a second side opposite the first side. The cavity CMC ply defines a cavity within the CMC airfoil. The insert is located between the first edge and the cavity. The insert is wrapped by a CMC ply such that the CMC ply extends along the insert from the first side of the CMC airfoil across the mean camber line of the CMC airfoil and to the second side of the CMC airfoil. The CMC ply terminates on the second side of the CMC airfoil.
FILED	Friday, June 16, 2017
APPL NO	15/624893
ART UNIT	3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/71 (20130101) C04B 35/622 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) F01D 5/282 (20130101) Original (OR) Class F01D 5/284 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/31 (20130101) F05D 2240/122 (20130101) F05D 2240/304 (20130101) F05D 2300/6033 (20130101) F05D 2300/6034 (20130101)
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10443838 — Method for forming consistently-sized and controllably-timed droplets

US 10443838	Baxter
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM) National Energy Technology Laboratory (NETL)
APPLICANT(S)	Larry Baxter (Orem, Utah)
ASSIGNEE(S)	Hall Labs LLC (Provo, Utah)
INVENTOR(S)	Larry Baxter (Orem, Utah)
ABSTRACT	A method for forming substantially consistently-sized and substantially controllably-timed droplets is disclosed. An opening is provided through which a protrusion passes. The protrusion ends at a tip below the opening. A process liquid is provided to the opening at a controlled flow rate. The process liquid passes through the opening and flows along the protrusion, forming a droplet of the process liquid on the tip that reaches a substantially consistent droplet size and falls. The process liquid continues to pass through the opening at an even time interval based on the flow rate. In this manner, substantially consistently-sized and substantially controllably-timed droplets are formed.
FILED	Wednesday, April 05, 2017
APPL NO	15/479471
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Separation B01D 53/62 (20130101) B01D 53/79 (20130101) B01D 53/504 (20130101) B01D 2257/302 (20130101) B01D 2257/304 (20130101) B01D 2257/404 (20130101) B01D 2257/504 (20130101) B01D 2259/124 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/02 (20130101) B05B 7/00 (20130101) Burners F23D 3/08 (20130101) F23D 11/44 (20130101) Original (OR) Class Feeding Fuel to Combustion Apparatus F23K 5/22 (20130101)
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10443905 — Magnetocaloric refrigeration using fully solid state working medium

US 10443905	Momen et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Ayyoub Mehdizadeh Momen (Knoxville, Tennessee); Omar Abdelaziz (Knoxville, Tennessee); Edward Allan Vineyard (Knoxville, Tennessee)
ABSTRACT	A magnetocaloric cooling system comprising a solid body or bodies, such as a cylinder or cube, having a plurality of channels extending between a first end and a second end of the cylinder or cube and a magnet at least partially surrounding the cylinder or cube. A metallic mass, such as a rod or plate, is positioned within each channel and slides within a respective channel between two sliding extremities so that in each sliding extremity, a portion of each metallic mass extends beyond an end of the solid body. A motor is used for reciprocating the metallic masses between the sliding extremities and a heat exchange mechanism directs heating or cooling where desired.
FILED	Tuesday, November 24, 2015
APPL NO	14/951191
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) Original (OR) Class F25B 2321/0021 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/66 (20130101)
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10443928 — Active magnetic regenerative liquefier using process gas pre-cooling from bypass flow of heat transfer fluid

US 10443928	Holladay et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington); John Barclay (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Jamie D. Holladay (Richland, Washington); Kerry D. Meinhardt (Kennewick, Washington); Evgueni Polikarpov (Richland, Washington); Edwin C. Thomsen (Richland, Washington); John Barclay (Richland, Washington); Jun Cui (Richland, Washington)
ABSTRACT	A process for liquefying a process gas that includes: introducing a heat transfer fluid into an active magnetic regenerative refrigerator apparatus that includes a low magnetic or demagnetized field section; continuously diverting a bypass portion of the heat transfer fluid from a cold side of the low magnetic or demagnetized field section into a bypass flow heat exchanger at a first cold inlet temperature; and continuously introducing the process gas into the bypass flow heat exchanger at a first hot inlet temperature and discharging the process gas or liquid from the bypass flow heat exchanger at a first cold exit temperature; wherein the temperature difference between bypass heat transfer first cold inlet temperature and the process gas first cold exit temperature is 1 to 5 K.
FILED	Tuesday, February 21, 2017
APPL NO	15/438529
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) F25B 2321/002 (20130101) Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 1/001 (20130101) F25J 1/0225 (20130101) Original (OR) Class F25J 2245/90 (20130101) F25J 2270/908 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/66 (20130101)
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10443954 — High performance metal hydride based thermal energy storage systems for concentrating solar power

US 10443954	Zidan
FUNDED BY	Department of Energy (DOE) Office of Environmental Management (DOE-EM) Savannah River National Laboratory (SRNL) Federally Funded Research and Development Center (FFRDC) Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S)	Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
ASSIGNEE(S)	SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina)
INVENTOR(S)	Ragaiy Zidan (Aiken, South Carolina)
ABSTRACT	Thermal energy storage (TES) systems based on metal hydride pairs using new class of high efficiency materials are evaluated. The use of low temperature metal cost effective material such hydrides NaAlH4 and Na3AlH6 became possible. In order to obtain high efficiency at reasonable cost high temperature materials were altered by the addition of materials to form reversible alloys and hydrides. The compounds were cycled to determine stability of hydrogen capacity over extended number of cycling. A thermal energy storage system based on two metal hydride pairs such as CaAl/CaH2/Al:NaAlH₄, Ca₂Si/CaH₂/Si:Na₃AlH₆and NaMgH₂F—Si/Mg2Si—NaF:Na₃AlH₆allows low cost and high efficiency performance.
FILED	Monday, December 07, 2015
APPL NO	14/961087
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 6/243 (20130101) C01B 21/072 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/003 (20130101) Original (OR) Class
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10444046 — Flow rate measurement in a volume

US 10444046	Galvez
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE)
APPLICANT(S)	NuScale Power, LLC (Corvallis, Oregon)
ASSIGNEE(S)	NUSCALE POWER, LLC (Corvallis, Oregon)
INVENTOR(S)	Cristhian Galvez (Corvallis, Oregon)
ABSTRACT	A system for measuring flow rate within a volume includes one or more transmission devices that transmit one or more signals through fluid contained within the volume. The volume may be bounded, at least in part, by an outer structure and by an object at least partially contained within the outer structure. A transmission device located at a first location of the outer structure transmits a first signal to a second location of the outer structure. A second signal is transmitted through the fluid from the second location to a third location of the outer structure. The flow rate of the fluid within the volume may be determined based, at least in part, on the time of flight of both the first signal and the second signal.
FILED	Monday, February 19, 2018
APPL NO	15/899251
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/66 (20130101) Original (OR) Class G01F 1/667 (20130101) Nuclear Reactors G21C 17/032 (20130101)
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10444110 — System and method for inspecting parts using frequency response function

US 10444110	Hartwig et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Kansas City National Security Campus (KCNSC) NNSA Critical Mission Site Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S)	HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri)
ASSIGNEE(S)	Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S)	Troy Hartwig (Kansas City, Missouri); Ben Brown (Kansas City, Missouri)
ABSTRACT	A system and method for the non-destructive testing of additively manufactured parts. An input mechanism excites with an excitation force (e.g., a vibration) an additive manufacturing build platform on which the part is located to induce a dynamic response in the part. An output mechanism (e.g., a non-contact transducer) senses the induced dynamic response in the part. A processor determines and examines the relationship between the response and excitation to identify an indication of a defect in the part, and communicates an alert if the indication is identified. The processor may compare the phase, magnitude, coherence, or time delay of the relationship to a reference relationship and/or may compare the modal frequency or the modal damping to a reference to identify a deviation greater than a pre-established threshold.
FILED	Friday, November 13, 2015
APPL NO	14/941258
ART UNIT	2861 — Printing/Measuring and Testing
CURRENT CPC	Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 7/022 (20130101) Original (OR) Class G01M 7/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/11 (20130101) G01N 29/12 (20130101) G01N 29/043 (20130101) G01N 29/045 (20130101) G01N 29/4427 (20130101) G01N 2291/012 (20130101) G01N 2291/014 (20130101) G01N 2291/015 (20130101) G01N 2291/2698 (20130101)
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10444202 — Nondestructive inspection using continuous ultrasonic wave generation

US 10444202	Flynn et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Eric B. Flynn (Santa Fe, New Mexico); Charles R. Farrar (Los Alamos, New Mexico); Gregory James Sylvester Jarmer (Albuquerque, New Mexico)
ABSTRACT	Methods and apparatus are disclosed for analyzing structures by applying a continuous ultrasonic excitation and measuring steady state response of the structures using laser Doppler vibrometery, or other techniques. In one example, a method comprises applying a continuous signal having one or more periodic tones to the structure, generating measurements of wave response to the signal at each of a plurality of inspection points of the structure, and, for each of the periodic tones, estimating wavenumbers for a number of the inspection points of the structure based on the wave response measurements and the frequency of the periodic tones. The estimated wavenumbers can be used to determine properties of the structure, including defects, damage, or variation in thickness.
FILED	Thursday, April 16, 2015
APPL NO	14/688854
ART UNIT	2812 — Semiconductors/Memory
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/12 (20130101) G01N 29/46 (20130101) Original (OR) Class G01N 29/265 (20130101) G01N 29/2418 (20130101) G01N 29/2437 (20130101) G01N 2291/02818 (20130101) G01N 2291/02827 (20130101) G01N 2291/02854 (20130101) G01N 2291/02881 (20130101)
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10444492 — Flexure-based, tip-tilt-piston actuation micro-array

US 10444492	Hopkins et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Jonathan Hopkins (Palo Alto, California); Robert Matthew Panas (Westborough, Massachusetts)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Jonathan Hopkins (Palo Alto, California); Robert Matthew Panas (Westborough, Massachusetts)
ABSTRACT	A flexure-based micro-array having a plurality of micro-assemblies, each comprising: an object; and at least three electrostatic actuation modules for tipping, tilting, and/or piston-actuating the object, each actuation module comprising: a base with first and second electrodes electrically isolated from each other; an electrically conductive lever arm; a first flexure bearing suspending the lever arm adjacent the first and second electrodes so that electrical activation of at least one of the first and second electrodes produces an electrostatic moment of force on the lever arm to resiliently bias the first flexure bearing and pivot the lever arm about a fulcrum; and a second flexure bearing connecting the lever arm to the object at a connection location that is different from other connection locations of the other actuation modules so that pivoting the lever arm about the fulcrum induces the second flexure bearing to pivot the object about an object pivot axis defined between two of the other connection locations while the second flexure bearing decouples the lever arm from object displacements induced by two of the other actuation modules connected to the two other connection locations defining the object pivot axis, wherein the plurality of micro-assemblies are arranged with the objects juxtaposed in a substantially 2D array.
FILED	Wednesday, March 19, 2014
APPL NO	14/218970
ART UNIT	2872 — Optics
CURRENT CPC	Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0062 (20130101) B81B 2201/033 (20130101) B81B 2203/053 (20130101) B81B 2203/058 (20130101) Optical Elements, Systems, or Apparatus G02B 26/0841 (20130101) Original (OR) Class
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10444526 — Optical pulse combiner comprising diffractive optical elements

US 10444526	Wilcox
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	Russell Wilcox (Berkeley, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Russell Wilcox (Berkeley, California)
ABSTRACT	This disclosure provides systems, methods, and apparatus related to optical systems. In one aspect, an optical system includes a plurality of optical sources, a first diffractive optical element, and a second diffractive optical element. The plurality of optical sources generates a plurality of pulsed beams that is less than about 1 picosecond in duration. The first diffractive optical element receives and diffracts the plurality of pulsed beams. The second diffractive optical element receives the diffracted plurality of pulsed beams and generates a combined pulsed beam.
FILED	Tuesday, July 25, 2017
APPL NO	15/658740
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 5/1861 (20130101) G02B 27/1086 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/067 (20130101) H01S 3/1307 (20130101) H01S 3/2383 (20130101)
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10444747 — Blended service schedule for a power generator

US 10444747	Keene et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Cummins Power Generation IP, Inc. (Minneapolis, Minnesota)
ASSIGNEE(S)	Cummins Power Generation IP, Inc. (Minneapolis, Minnesota)
INVENTOR(S)	Kevin Keene (Minneapolis, Minnesota); Benjamin S. Fuchs (Minneapolis, Minnesota)
ABSTRACT	A power generation system includes a power generator operatively connected to a plurality of sensors and a processor. The processor is configured to observe usage-based or event-based data regarding one or more components and consumables of the power generator. A usage-based service schedule is observed for the one or more event-based components and consumables. Operation-based data is received from the plurality of sensors regarding the functioning of the power generation system and one or more operation-based components and consumables of the power generator. An operation-based service schedule is determined for the one or more operation-based components and consumables based on the operation-based data. A blended service schedule is generated, the blended service schedule including the usage-based service schedule and the operation-based service schedule. The blended service schedule is then provided to at least one of a local monitor or a remote monitor.
FILED	Thursday, March 26, 2015
APPL NO	14/669983
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/00 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 23/0283 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0639 (20130101) G06Q 50/06 (20130101)
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10445065 — Constant depth, near constant depth, and subcubic size threshold circuits for linear algebraic calculations

US 10445065	Aimone et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	James Bradley Aimone (Albuquerque, New Mexico); Ojas D. Parekh (Albuquerque, New Mexico); Cynthia A. Phillips (Albuquerque, New Mexico)
ABSTRACT	A method of increasing an efficiency at which a plurality of threshold gates arranged as neuromorphic hardware is able to perform a linear algebraic calculation having a dominant size of N. The computer-implemented method includes using the plurality of threshold gates to perform the linear algebraic calculation in a manner that is simultaneously efficient and at a near constant depth. “Efficient” is defined as a calculation algorithm that uses fewer of the plurality of threshold gates than a naïve algorithm. The naïve algorithm is a straightforward algorithm for solving the linear algebraic calculation. “Constant depth” is defined as an algorithm that has an execution time that is independent of a size of an input to the linear algebraic calculation. The near constant depth comprises a computing depth equal to or between O(log(log(N)) and the constant depth.
FILED	Friday, September 08, 2017
APPL NO	15/699077
ART UNIT	2182 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 7/4833 (20130101) Original (OR) Class G06F 7/4876 (20130101) G06F 17/12 (20130101) G06F 17/16 (20130101) G06F 2207/4822 (20130101) G06F 2207/4835 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0635 (20130101)
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10445094 — Method and apparatus for reordering in a non-uniform compute device

US 10445094	Beard et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	ARM Limited (Cambridge, United Kingdom)
ASSIGNEE(S)	Arm Limited (Cambridge, United Kingdom)
INVENTOR(S)	Jonathan Curtis Beard (Austin, Texas); Wendy Elsasser (Austin, Texas); Shibo Wang (Austin, Texas)
ABSTRACT	A data processing apparatus includes a multi-level memory system, one or more first processing unit coupled to the memory system at a first level and one or more second processing units each coupled to the memory system at a second level. A first reorder buffer maintains data order during execution of instructions by the first and second processing units and a second reorder buffer maintains data order during execution of the instructions by an associated second processing unit. An entry in the first reorder buffer is configured, dependent upon an indicator bit, as an entry for a single instruction or a pointer to an entry in the second reorder buffer. An entry in the second reorder buffer includes instruction block start and end addresses and indicators of input and output register. Instructions are released to a processing unit when all inputs, as indicated by the reorder buffers, are available.
FILED	Friday, May 27, 2016
APPL NO	15/166467
ART UNIT	2183 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 9/32 (20130101) G06F 9/3004 (20130101) G06F 9/3005 (20130101) Original (OR) Class G06F 9/3836 (20130101) G06F 9/3855 (20130101) G06F 9/30098 (20130101) G06F 12/084 (20130101) G06F 12/0811 (20130101) G06F 12/0875 (20130101) G06F 12/0893 (20130101) G06F 15/7821 (20130101) G06F 2212/62 (20130101) G06F 2212/452 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/13 (20180101)
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10445110 — Modular space vehicle boards, control software, reprogramming, and failure recovery

US 10445110	Judd et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Stephen Judd (Los Alamos, New Mexico); Nicholas Dallmann (Los Alamos, New Mexico); Kevin McCabe (Santa Fe, New Mexico); Jerry Delapp (Los Alamos, New Mexico); Dean Prichard (Los Alamos, New Mexico); Michael Proicou (Los Alamos, New Mexico); Daniel Seitz (Los Alamos, New Mexico); Paul Stein (Los Alamos, New Mexico); John Michel (Santa Fe, New Mexico); Justin Tripp (Los Alamos, New Mexico); Joseph Palmer (Los Alamos, New Mexico); Steven Storms (Los Alamos, New Mexico)
ABSTRACT	A space vehicle may have a modular board configuration that commonly uses some or all components and a common operating system for at least some of the boards. Each modular board may have its own dedicated processing, and processing loads may be distributed. The space vehicle may be reprogrammable, and may be launched without code that enables all functionality and/or components. Code errors may be detected and the space vehicle may be reset to a working code version to prevent system failure.
FILED	Thursday, February 23, 2017
APPL NO	15/440836
ART UNIT	2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electric Digital Data Processing G06F 9/44505 (20130101) Original (OR) Class G06F 11/0739 (20130101) G06F 11/0757 (20130101) G06F 11/1417 (20130101) G06F 11/1433 (20130101)
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10445160 — Remote monitoring of critical reactor parameters

US 10445160	Pottorf et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE)
APPLICANT(S)	NuScale Power, LLC (Corvallis, Oregon)
ASSIGNEE(S)	NUSCALE POWER, LLC (Corvallis, Oregon)
INVENTOR(S)	Jason Pottorf (Corvallis, Oregon); Ted Hough (Corvallis, Oregon)
ABSTRACT	A nuclear reactor instrumentation system monitors a nuclear power system that includes a reactor core within a reactor vessel and one or more sensors for monitoring parameters of the nuclear power system. The nuclear reactor instrumentation system includes a computer having a processor and configured to be powered by a normal power source and a backup power source; a wireless transmitter operable under the control of the processor; and a memory coupled to the processor and containing stored programming instructions. The stored programming instructions are executable by the processor to cause the processor to receive data from the sensors; identify a loss of normal power from the normal power source; and in response to identifying the loss of normal power, cause the wireless transmitter to transmit the received data.
FILED	Thursday, December 17, 2015
APPL NO	14/973299
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Electric Digital Data Processing G06F 11/00 (20130101) Original (OR) Class Nuclear Reactors G21C 17/00 (20130101) Nuclear Power Plant G21D 1/00 (20130101) G21D 3/04 (20130101) G21D 3/06 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/40 (20130101)
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10445530 — Hardware intrusion detection system

US 10445530	Edwards
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Nathan J. Edwards (Albuquerque, New Mexico)
ABSTRACT	An apparatus for intrusion detection includes processing circuitry, a switch, signal detection circuitry, and an analog-to-digital converter (“ADC”). The processing circuitry is coupled to send a challenge signal to a device when the device is coupled to the processing circuitry. The switch is coupled to be enabled and disabled by the processing circuitry. The switch is for coupling to the device to receive a response signal in response to the challenge signal sent by the processing circuitry. The signal detection circuitry is coupled to receive the response signal in via the switch, when the processing circuitry enables the switch. The ADC is coupled to take measurements of the signal detection circuitry at a first output. The processing circuitry is coupled to the ADC and configured to analyze whether an intruder is present in the device based on the measurements of the signal detection circuitry.
FILED	Friday, March 15, 2013
APPL NO	13/834673
ART UNIT	2491 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/76 (20130101) Original (OR) Class
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10445862 — Efficient track-before detect algorithm with minimal prior knowledge

US 10445862	Merry et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Kyle Merry (Albuquerque, New Mexico); Ross L. Hansen (Albuquerque, New Mexico)
ABSTRACT	Apparatus, system and method for tracking an image target in a system, wherein a system receives an image comprising a plurality of pixels. The received image is processed via a plurality of different recursive motion model kernels in parallel to provide a plurality of kernel outputs, wherein each of the motion model kernels may include a respective pixel mask. Per-pixel energy is estimated of at least some of the plurality of kernel outputs. Velocity of at least one of the image pixels may also be estimated by generating a directional energy vector for each motion model kernel. The per-pixel energy and velocity estimates are fused to produce a fused estimate representing at least some of the motion model kernels for the image.
FILED	Monday, January 16, 2017
APPL NO	15/407104
ART UNIT	2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Electric Digital Data Processing G06F 16/24545 (20190101) G06F 17/11 (20130101) G06F 17/16 (20130101) Image Data Processing or Generation, in General G06T 5/004 (20130101) Original (OR) Class G06T 7/20 (20130101) G06T 7/35 (20170101) G06T 7/251 (20170101)
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10446369 — Systems and methods for interferometric end point detection for a focused ion beam fabrication tool

US 10446369	Phillips et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Brian Scott Phillips (Rio Rancho, New Mexico); Steven Norris Ball (Albuquerque, New Mexico); Gregory Paul Salazar (Rio Rancho, New Mexico); Randy J. Shul (Albuquerque, New Mexico)
ABSTRACT	Various technologies for providing an operator of a focused ion beam (FIB) system with navigational and processing data are described herein. An exemplary system includes a broadband light source and a narrowband light source that emit light to a target of the FIB. An optical detector receives reflections of the broadband light from the target and outputs data that is used to generate two-dimensional images of the target in a region near a location of incidence of the FIB at the target. An interferometer receives reflections of the narrowband light from the target and outputs data indicative of an interference pattern of the narrowband reflections. A computing device computes a thickness of one or more material layers that make up the target based upon the interference pattern. A two-dimensional image of the target and an indication of the computed thickness are then displayed to the operator of the FIB.
FILED	Wednesday, June 14, 2017
APPL NO	15/623239
ART UNIT	2884 — Optics
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/14 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/3005 (20130101) Original (OR) Class H01J 2237/31749 (20130101)
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10446704 — Formation of Ohmic back contact for Ag₂ZnSn(S,Se)₄photovoltaic devices

US 10446704	Gershon et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Talia S. Gershon (White Plains, New York); Oki Gunawan (Westwood, New Jersey); Richard A. Haight (Mahopac, New York); Ravin Mankad (Yonkers, New York)
ABSTRACT	Techniques for forming an ohmic back contact for Ag₂ZnSn(S,Se)₄photovoltaic devices. In one aspect, a method for forming a photovoltaic device includes the steps of: depositing a refractory electrode material onto a substrate; depositing a contact material onto the refractory electrode material, wherein the contact material includes a transition metal oxide; forming an absorber layer on the contact material, wherein the absorber layer includes Ag, Zn, Sn, and at least one of S and Se; annealing the absorber layer; forming a buffer layer on the absorber layer; and forming a top electrode on the buffer layer. The refractory electrode material may be Mo, W, Pt, Ti, TiN, FTO, and combinations thereof. The transition metal oxide may be TiO₂, ZnO, SnO, ZnSnO, Ga₂O₃, and combinations thereof. A photovoltaic device is also provided.
FILED	Wednesday, December 30, 2015
APPL NO	14/984512
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/072 (20130101) H01L 31/0326 (20130101) Original (OR) Class H01L 31/022425 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101)
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10446706 — Hexagonal phase epitaxial cadmium sulfide on copper indium gallium selenide for a photovoltaic junction

US 10446706	Mackie et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	BEIJING APOLLO DING RONG SOLAR TECHNOLOGY CO., LTD. (Beijing, China PRC); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S)	BEIJING APOLLO DING RONG SOLAR TECHNOLOGY CO., LTD. (Beijing, China PRC); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S)	Neil Mackie (Fremont, California); Geordie Zapalac (San Francisco, California); Weijie Zhang (San Jose, California); John F. Corson (Mountain View, California); Xiaoqing He (Champaign, Illinois); Angus Rockett (Champaign, Illinois); Joel Varley (San Francisco, California); Vincenzo Lordi (San Francisco, California)
ABSTRACT	A method of manufacturing a photovoltaic structure includes forming a p-type semiconductor absorber layer containing a copper indium gallium selenide based material over a first electrode, forming a n-type cadmium sulfide layer over the p-type semiconductor absorber layer by sputtering in an ambient including hydrogen gas and oxygen gas, and forming a second electrode over the cadmium sulfide layer.
FILED	Thursday, May 12, 2016
APPL NO	15/153478
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02485 (20130101) H01L 21/02557 (20130101) H01L 21/02631 (20130101) H01L 31/18 (20130101) H01L 31/036 (20130101) H01L 31/0296 (20130101) H01L 31/0749 (20130101) Original (OR) Class H01L 31/1828 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/541 (20130101) Y02E 10/543 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101)
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10446732 — NbFeSb-based half-heusler thermoelectric materials and methods of making

US 10446732	Zhu et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	ZHEJIANG UNIVERSITY (Hangzhou, Zhejiang Province, China PRC)
ASSIGNEE(S)	ZHEJIANG UNIVERSITY (Hangzhou, China PRC)
INVENTOR(S)	Tiejun Zhu (Hangzhou, China PRC); Chenguang Fu (Hangzhou, China PRC); Xinbing Zhao (Hangzhou, China PRC)
ABSTRACT	A thermoelectric half-Heusler material comprising niobium (Nb), iron (Fe) and antimony (Sb) wherein the material comprises grains having a mean grain size less than one micron. A method of making a nanocomposite half-Heusler thermoelectric material includes melting constituent elements of the thermoelectric material to form an alloy of the thermoelectric material, comminuting (e.g., ball milling) the alloy of the thermoelectric material into nanometer scale mean size particles, and consolidating the nanometer size particles to form the half-Heusler thermoelectric material comprising at least niobium (Nb), iron (Fe) and antimony (Sb) and having grains with a mean grain size less than one micron.
FILED	Tuesday, May 27, 2014
APPL NO	14/900132
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/18 (20130101) Original (OR) Class H01L 35/34 (20130101)
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10446817 — Energy storage device and related methods

US 10446817	Jarvis et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	ALCOA INC. (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Arconic Inc. (Pittsburgh, Pennsylvania)
INVENTOR(S)	Glenn W. Jarvis (Allison Park, Pennsylvania); Robert E. Dick (Cheswick, Pennsylvania); Hasso Weiland (Lower Burrell, Pennsylvania); Joseph M. Fridy (Pittsburgh, Pennsylvania); David J. McNeish (Greensburg, Pennsylvania); John W. Cobes (Lower Burrell, Pennsylvania); Rabindra K. Bhattacharyya (Export, Pennsylvania); John M. Krish (Apollo, Pennsylvania); David M. Ference (New Kensington, Pennsylvania); Brock Watters (Livonia, Michigan); Gregory Catrambone (Lemont, Illinois)
ABSTRACT	The present disclosure relates to energy storage devices having: a sealed container configured to house a plurality of energy storage devices and enable electrical communication via terminals of the sealed container and a vent located on a periphery of the sealed container. The vent generally comprises a vent panel; a countersink located adjacent the vent panel; at least one score located in the countersink; a buckling initiator at least partially located on the countersink, where the buckling initiator is configured to intersect with the at least one score; and a hinge portion attached to the vent panel, where the hinge portion is positioned opposite the buckling initiator.
FILED	Monday, October 03, 2016
APPL NO	15/283830
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/12 (20130101) H01M 2/345 (20130101) H01M 2/1241 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2200/20 (20130101)
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10446855 — Fuel cell system including multilayer interconnect

US 10446855	Liu et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	LG Fuel Cell Systems, Inc. (North Canton, Ohio)
ASSIGNEE(S)	LG FUEL CELL SYSTEMS INC. (Canton, Ohio)
INVENTOR(S)	Zhien Liu (Canton, Ohio); Richard W. Goettler (Medina, Ohio); Hwa-Young Jung (Canton, Ohio); Minjae Jung (Stow, Ohio)
ABSTRACT	In some examples, a fuel cell comprising a first electrochemical cell including a first anode and a first cathode; a second electrochemical cell including a second anode and a second cathode; and an interconnect configured to conduct a flow of electrons from the first anode to the second cathode, wherein the interconnect comprises a first portion and a second portion, wherein the first portion is closer to the anode than the second portion, and the second portion is closer to the cathode than the first portion, wherein the first portion comprises one or more of doped ceria, doped lanthanum chromite, and doped yttrium chromite, and wherein the second portion comprises one or more of a Co—Mn spinel and a ABO₃perovskite.
FILED	Friday, December 13, 2013
APPL NO	14/106298
ART UNIT	1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0217 (20130101) H01M 8/0219 (20130101) H01M 8/0228 (20130101) H01M 8/0236 (20130101) Original (OR) Class H01M 2008/1293 (20130101)
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10446861 — Flowing electrolyte fuel cell with improved performance and stability

US 10446861	Desai et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S)	Divyaraj Desai (Sunnyvale, California); Vedasri Vedharathinam (San Jose, California); Martin Joseph Sheridan (Redwood City, California); Ashish V. Pattekar (Cupertino, California); Craig Eldershaw (Belmont, California); Rajesh Kumar Padmarajan (Mountain View, California); Gabriel Iftime (Dublin, California)
ABSTRACT	A flowing electrolyte fuel cell system design (DHCFC-Flow) is provided. The use of a flowing oxygen-saturated electrolyte in a fuel cell offers a significant enhancement in the cell performance characteristics. The mass transfer and reaction kinetics of the superoxide/peroxide/oxide ion (mobile oxygen ion species) in the fuel cell are enhanced by recirculating an oxidizing gas-saturated electrolyte. Recirculating oxygen-saturated electrolyte through a liquid channel enhances the maximal current observed in a fuel cell. The use of a oxygen saturated electrolyte ensures that the reaction kinetics of the oxygen reduction reaction are fast and the use of convection ameliorates concentration gradients and the diffusion-limited maximum current density. The superoxide ion is generated in situ by the reduction of the oxygen dissolved in the gaseous electrolyte. Also, a dual porosity membrane allows the uniform flow of fuel (e.g., methane) on the fuel side, without allowing phase mixing. The capillary pressure for liquid intrusion into the gas phase and vice versa is quite large, estimated to be 1-10 psi. This makes it easier to control the fluctuations in gas/liquid velocity which might otherwise lead to phase mixing and the loss of fuel cell performance. In one variation, a dual-porosity membrane structure is incorporated in the system to allow uniform flow of fuel and prevent mixing of fuel with a liquid electrolyte.
FILED	Monday, December 28, 2015
APPL NO	14/981104
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8626 (20130101) H01M 8/22 (20130101) H01M 8/023 (20130101) H01M 8/188 (20130101) H01M 8/2455 (20130101) H01M 8/04283 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101)
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10446868 — Fuel cell subassemblies incorporating subgasketed thrifted membranes

US 10446868	Iverson et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	3M INNOVATIVE PROPERTIES COMPANY (St. Paul, Minnesota)
ASSIGNEE(S)	3M INNOVATIVE PROPERTIES COMPANY (Saint Paul, Minnesota)
INVENTOR(S)	Eric J. Iverson (Eau Claire, Wisconsin); Daniel M. Pierpont (North Saint Paul, Minnesota); Michael A. Yandrasits (Hastings, Minnesota); Steven J. Hamrock (Stillwater, Minnesota); Stephan J. Obradovich (Menomonie, Wisconsin); Donald G. Peterson (Shoreview, Minnesota)
ABSTRACT	An automated roll to roll method of making a fuel cell roll good subassembly is described wherein an elongated first subgasket web having a plurality of apertures is moved relative to a plurality of individual electrolyte membranes, each individual electrolyte membrane having a center region. The individual electrolyte membranes are aligned with the first subgasket web so that a center region of each electrolyte membrane is aligned with an aperture of the first subgasket web and the individual electrolyte membranes are attached to the first subgasket web.
FILED	Monday, January 25, 2016
APPL NO	15/005571
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/242 (20130101) H01M 8/0273 (20130101) H01M 8/0276 (20130101) H01M 8/0286 (20130101) H01M 8/1004 (20130101) H01M 8/1016 (20130101) H01M 8/2418 (20160201) Original (OR) Class H01M 2008/1095 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/56 (20151101)
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10446886 — Embedded fiber optic cables for battery management

US 10446886	Raghavan et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S)	Ajay Raghavan (Mountain View, California); Peter Kiesel (Palo Alto, California); Lars Wilko Sommer (Bretten, Germany); Bhaskar Saha (Redwood City, California); Saroj Sahu (Fremont, California); Alexander Lochbaum (Landau, Germany); Tobias Staudt (Neurnberg, Germany); Chang-Jun Bae (Mountain View, California); Mohamed Alamgir (Rochester Hills, Michigan); Hoe Jin Hah (Daejeon, South Korea); Bokkyu Choi (Tokyo, Japan); Gyu-Ok Hwang (Daejeon, South Korea); Geun-Chang Chung (Daejeon, South Korea)
ABSTRACT	A battery includes a folded bicell battery stack with an embedded fiber optic cable and sensor. A cell casing encloses the bicell stack with at least one fiber optic cable is embedded within the battery. The fiber optic cable includes an internal portion disposed within the cell casing and having at least one optical sensor disposed thereon. An external portion of the fiber optic cable protrudes from the casing. A sealing gasket is disposed at least partially around the fiber optic cable and between the cell sealing edges at a point of entry of the fiber optic cable into the battery.
FILED	Wednesday, July 23, 2014
APPL NO	14/339050
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/32 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/242 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/06 (20130101) H01M 2/08 (20130101) H01M 2/1061 (20130101) H01M 10/052 (20130101) H01M 10/0431 (20130101) H01M 10/0459 (20130101) H01M 10/482 (20130101) Original (OR) Class H01M 10/486 (20130101) H01M 10/4257 (20130101)
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10447038 — Microgrids with dynamically configurable boundaries including multiple main grid feeder coupling locations and methods of operating the same

US 10447038	Wang et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S)	University of Tennessee Research (Knoxville, Tennessee)
INVENTOR(S)	Fei Wang (Knoxville, Tennessee); Xiaojie Shi (Knoxville, Tennessee); Leon M. Tolbert (Knoxville, Tennessee); Yiwei Ma (Knoxville, Tennessee); Yilu Liu (Knoxville, Tennessee); Lin Zhu (Knoxville, Tennessee)
ABSTRACT	An energy system includes a microgrid including a network of at least one distributed energy resource and a plurality of loads, the at least one distributed energy resource being configured to supply power to the plurality of loads. The microgrid is configurable to connect to one of a plurality of feeder circuits of a main power grid at one of a plurality of coupling interface locations, respectively. The microgrid is also configurable to expand or shrink its power supply area according to the available power generation capabilities.
FILED	Friday, November 10, 2017
APPL NO	15/809329
ART UNIT	2117 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/14 (20130101) Original (OR) Class H02J 3/381 (20130101) H02J 13/0017 (20130101)
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10447043 — Verifying status of a termination end cap of a microinverter chain

US 10447043	Chapman et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	SunPower Corporation (San Jose, California)
ASSIGNEE(S)	SunPower Corporation (San Jose, California)
INVENTOR(S)	Patrick L Chapman (Austin, Texas); Philip Rothblum (Austin, Texas)
ABSTRACT	A photovoltaic (PV) system includes a system control module that determines the presence of a microinverter chain termination end cap. The end cap includes an embedded circuit. The embedded circuit includes components having resistive, reactive, or impedance values. A signal source provides a signal through the microinverter chain. A parameter for a sensed signal detected by the system control module is used to determine the presence of the end cap using a change between the parameter for the sense signal and a reference parameter.
FILED	Tuesday, May 24, 2016
APPL NO	15/163359
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/383 (20130101) Original (OR) Class Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 50/10 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/563 (20130101)
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10447046 — Secondary battery management system with remote parameter estimation

US 10447046	Ravi et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Robert Bosch GmbH (Stuttgart, Germany)
ASSIGNEE(S)	Robert Bosch GmbH (Stuttgart, Germany)
INVENTOR(S)	Nikhil Ravi (Mountain View, California); Anahita MirTabatabaei (San Francisco, California); Reinhardt Klein (Mountain View, California); Ashish Krupadanam (Cupertino, California); John F. Christensen (Elk Grove, California)
ABSTRACT	A battery system, having a battery management system configured to determine the state of charge and state of health of a secondary battery. The battery management system may export data to and receive inputs from a remote computer which calculates at least a portion of the state of health of the battery.
FILED	Thursday, September 22, 2016
APPL NO	15/273040
ART UNIT	2851 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/367 (20190101) Electric Digital Data Processing G06F 1/28 (20130101) G06F 1/30 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/425 (20130101) H01M 2010/4271 (20130101) H01M 2010/4278 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/007 (20130101) H02J 7/0021 (20130101) Original (OR) Class H02J 13/0003 (20130101)
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10447054 — Staircase charging

US 10447054	Christensen et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Robert Bosch GmbH (Stuttgart, Germany)
ASSIGNEE(S)	Robert Bosch GmbH (Stuttgart, Germany)
INVENTOR(S)	John F. Christensen (Elk Grove, California); Reinhardt Klein (Mountain View, California); Ashish Krupadanam (Cupertino, California); Anahita MirTabatabaei (San Francisco, California); Nikhil Ravi (Mountain View, California)
ABSTRACT	A battery management system comprising a processor and a memory storing instructions that, when executed by the processor, cause the battery management system to estimate one or more states of the battery by applying a battery model to account for physical parameters of a chemical composition of the battery based on one or more measured characteristics of the battery and the one or more estimated characteristics of the battery and regulate a first charging mode of the battery based on the estimation of the one or more states of the one or more battery cells and switch between the first charging mode and a second charging mode based on the estimation of the one or more states of the battery to allow for rapid charging of the battery.
FILED	Friday, May 20, 2016
APPL NO	15/160659
ART UNIT	2859 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3651 (20130101) G01R 31/3679 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/48 (20130101) H01M 10/425 (20130101) H01M 10/441 (20130101) H01M 2010/4271 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/007 (20130101) Original (OR) Class H02J 7/0021 (20130101)
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10447110 — Halbach-array radial stabilizer for a passive magnetic bearing

US 10447110	Post
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Richard F Post (Walnut Creek, California)
ABSTRACT	A radial stabilizer is provided for stabilizing levitation passive bearing elements against lateral displacements. The stabilizer provides a means to introduce anisotropy in the radial stiffness of the stabilizer. The presence of anisotropic stiffness has a strongly stabilizing effect on whirl-type rotor-dynamic instabilities. The stabilizer design also provides a means for continuously monitoring the state of health of the rotor by signaling the onset of changes of balance that would be expected to precede any major failure.
FILED	Wednesday, June 01, 2016
APPL NO	15/170864
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 32/041 (20130101) F16C 32/0436 (20130101) Dynamo-electric Machines H02K 7/09 (20130101) Original (OR) Class H02K 11/26 (20160101)
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10447273 — Dynamic virtualized field-programmable gate array resource control for performance and reliability

US 10447273	Roberts et al.
FUNDED BY	Department of Energy (DOE) Exascale Computing Project (ECP) PathForward Project (PATHFORWARD) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S)	Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S)	David A. Roberts (Boxborough, Massachusetts); Shenghsun Cho (Boxborough, Massachusetts)
ABSTRACT	A method for allocating field-programmable gate array (FPGA) resources includes monitoring a first operating metric for one or more computing devices, identifying a first portion of plurality of macro components of a set of one or more FPGA devices in the one or more computing devices, where the first portion is allocated for implementing one or more user defined functions. The method also includes, in response to a first change in the first operating metric, reallocating the first portion of the macro components for implementing a system function associated with the first operating metric, and generating a first notification indicating the reallocation of the first portion.
FILED	Tuesday, September 11, 2018
APPL NO	16/128014
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 9/4881 (20130101) G06F 11/3024 (20130101) G06F 11/3409 (20130101) Pulse Technique H03K 19/17752 (20130101) Original (OR) Class
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10447297 — Electronic device and method for compressing sampled data

US 10447297	Tohlen et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Kansas City National Security Campus (KCNSC) NNSA Critical Mission Site Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S)	Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
ASSIGNEE(S)	Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S)	Michael Tohlen (Kansas City, Missouri); Derek Welty (Kansas City, Missouri); Mitchell Morrow (Kansas City, Missouri)
ABSTRACT	An electronic device for compressing sampled data comprises a memory element and a processing element. The memory element is configured to store sampled data points and sampled times. The processing element is in electronic communication with the memory element and is configured to receive a plurality of sampled data points, a slope for each sampled data point in succession, the slope being a value of a change between the sampled data point and its successive sampled data point, and store the sampled data point in the memory element when the slope changes in value from a previous sampled data point.
FILED	Wednesday, October 03, 2018
APPL NO	16/150355
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/0608 (20130101) G06F 3/0661 (20130101) G06F 3/0673 (20130101) Coding; Decoding; Code Conversion in General H03M 7/6058 (20130101) Original (OR) Class
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10448496 — Superconducting cavity coupler

US 10448496	Kazakov
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Fermi National Accelerator Laboratory (FNAL) Federally Funded Research and Development Center (FFRDC) Operated by Fermi Research Alliance, LLC (FRA) at Batavia, IL
APPLICANT(S)	Fermi Research Alliance, LLC (Batavia, Illinois)
ASSIGNEE(S)	Fermi Research Alliance, LLC (Batavia, Illinois)
INVENTOR(S)	Sergey Kazakov (Batavia, Illinois)
ABSTRACT	A cavity coupler comprising of an outer coupler body, at least one shield formed inside the outer coupler body wherein the relationship between the shield and the outer coupler body form at least one chamber, an antenna configured to provide a radio frequency signal, and a flange for connecting the cavity coupler to a superconducting cavity. In an embodiment, the outer coupler body is formed of stainless steel. In an embodiment, the at least one shield is formed of copper.
FILED	Wednesday, September 28, 2016
APPL NO	15/278299
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 5/103 (20130101) H01P 7/06 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/20 (20130101) Original (OR) Class
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National Science Foundation (NSF)

10440911 — Targeted modification of maize roots to enhance abiotic stress tolerance

US 10440911	Kaeppler et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Organismal Systems (IOS) Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Penn State Research Foundation (University Park, Pennsylvania); The University of Nottingham (East Midlands, United Kingdom)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Shawn Michael Kaeppler (Oregon, Wisconsin); Patompong Saengwilai (Bangkok, Thailand); Jonathan Paul Lynch (Boalsburg, Pennsylvania); Malcolm John Bennett (Nottingham, United Kingdom); James Johnson (Whitestown, Indiana)
ABSTRACT	The present invention relates to crop breeding. More particularly, the present invention relates to targeted modification of root to enhance abiotic stress tolerance in maize. In one aspect, the invention provides recombinant maize exhibiting increased root cortical aerenchyma (RCA). Methods of making the recombinant maize and various methods of plant selection and breeding are further provided.
FILED	Thursday, September 14, 2017
APPL NO	15/704502
ART UNIT	1663 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/06 (20130101) A01H 5/10 (20130101) Original (OR) Class A01H 6/4684 (20180501) Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/82 (20130101) C12N 15/8242 (20130101) C12N 15/8271 (20130101)
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10441185 — Flexible and stretchable electronic systems for epidermal electronics

US 10441185	Rogers et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Neurological Disorders and Stroke (NINDS) Tissue Engineering Resource Center (TERC) National Science Foundation (NSF)
APPLICANT(S)	John A. Rogers (Champaign, Illinois); Dae-Hyeong Kim (Champaign, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	John A. Rogers (Champaign, Illinois); Dae-Hyeong Kim (Champaign, Illinois)
ABSTRACT	Provided herein are skin-mounted biomedical devices and methods of making and using biomedical devices for sensing and actuation applications. For example, flexible and/or stretchable biomedical devices are provided, including electronic devices useful for establishing conformal contact with the skin of a subject. Devices disclosed herein can comprise a plurality of sensing and/or actuating devices provided as part of a skin-mounted flexible or stretchable electronic circuit.
FILED	Friday, June 08, 2012
APPL NO	13/492636
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/076 (20130101) A61B 5/0422 (20130101) A61B 5/0478 (20130101) A61B 5/0492 (20130101) A61B 5/0537 (20130101) A61B 5/1104 (20130101) A61B 5/1107 (20130101) A61B 5/04085 (20130101) Original (OR) Class A61B 5/04284 (20130101) A61B 5/4875 (20130101) A61B 5/6867 (20130101) A61B 2562/02 (20130101) A61B 2562/12 (20130101) A61B 2562/029 (20130101) A61B 2562/046 (20130101) A61B 2562/066 (20130101) A61B 2562/164 (20130101) A61B 2562/0261 (20130101) A61B 2562/0271 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/36 (20130101) A61N 1/0472 (20130101) A61N 1/0587 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/3121 (20130101) H01L 23/3192 (20130101) H01L 27/1218 (20130101) H01L 29/7869 (20130101) H01L 29/78603 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2924/3011 (20130101) H01L 2924/3025 (20130101) H01L 2924/12044 (20130101) H01L 2924/19041 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/147 (20130101) H05K 1/189 (20130101) H05K 1/0283 (20130101) H05K 3/323 (20130101) H05K 2201/09263 (20130101)
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10441371 — Concentric tube robot

US 10441371	Hendrick et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Vanderbilt University (Nashville, Ohio)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	Richard J. Hendrick (Nashville, Tennessee); Robert J. Webster, III (Nashville, Tennessee); S. Duke Herrell (Nashville, Tennessee); Philip J. Swaney (Nashville, Tennessee); Ray Lathrop (Indianapolis, Indiana)
ABSTRACT	A robotic surgical apparatus includes at least two tubes having a nested, concentric configuration with an inner tube positioned in an outer tube. The tubes are configured to deliver surgical therapy. A first tube carrier connected to the outer tube and a second tube carrier connected to the inner tube. The first tube carrier and its associated outer tube and the second tube carrier and its associated inner tube form a robotic arm assembly. An actuator for actuating the robotic arm assembly is configured to receive the robotic arm assembly via a tube insertion interface into which the robotic arm assembly can be inserted.
FILED	Monday, October 03, 2016
APPL NO	15/283775
ART UNIT	3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/05 (20130101) A61B 1/00039 (20130101) A61B 1/00087 (20130101) A61B 1/00101 (20130101) A61B 1/00133 (20130101) A61B 17/00234 (20130101) A61B 34/30 (20160201) Original (OR) Class A61B 34/72 (20160201) A61B 2017/00296 (20130101) A61B 2017/00318 (20130101) A61B 2017/00345 (20130101) A61B 2034/301 (20160201) A61B 2034/302 (20160201) A61B 2034/742 (20160201)
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10441610 — Protein delivery from stem cell microcarriers

US 10441610	Boyan et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Barbara Dale Boyan (Richmond, Virginia); Zvi Schwartz (Richmond, Virginia); Christopher S. D. Lee (Atlanta, Georgia); Shirae Kerisha Leslie (Richmond, Virginia); Ramsey C. Kinney (Decatur, Georgia)
ASSIGNEE(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Barbara Dale Boyan (Richmond, Virginia); Zvi Schwartz (Richmond, Virginia); Christopher S. D. Lee (Atlanta, Georgia); Shirae Kerisha Leslie (Richmond, Virginia); Ramsey C. Kinney (Decatur, Georgia)
ABSTRACT	Disclosed are methods and compositions of microbead carriers for delivery of cells and other biologically active substances to diseased or damaged tissue in a subject in need thereof.
FILED	Wednesday, November 23, 2011
APPL NO	13/988929
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/5036 (20130101) A61K 35/28 (20130101) Original (OR) Class A61K 2035/128 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0655 (20130101) C12N 5/0667 (20130101) C12N 2500/25 (20130101) C12N 2500/32 (20130101) C12N 2500/34 (20130101) C12N 2500/38 (20130101) C12N 2501/15 (20130101) C12N 2501/39 (20130101) C12N 2501/155 (20130101) C12N 2533/74 (20130101)
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10441637 — Methods for structural determination of selenium derivatized nucleic acid complexes

US 10441637	Huang
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	SeNA Research, Inc. (Marietta, Georgia)
ASSIGNEE(S)	SeNA Research, Inc. (Marietta, Georgia)
INVENTOR(S)	Zhen Huang (Marietta, Georgia)
ABSTRACT	Methods for crystallizing a molecule of interest, such as a polypeptide, in complex with nucleic acid, including contacting the molecule of interest with selenium-derivatized nucleic acid and crystallizing the molecule of interest/selenium-derivatized nucleic acid complex are provided. Methods for determining the X-ray crystal structure of molecule of interest/selenium-derivatized nucleic acid complexes are also provided. Typically, the method of X-ray crystal structural determination includes selenium single-wavelength anomalous phasing of the selenium-derivatized nucleic acid. In some embodiments the phases for the X-ray crystal structure of the molecule of interest are not provided from another crystal. Also disclosed are methods of affecting a biological process by administering a functional nucleic acid to a cell or a subject and/or by bringing into contact a nuclease and a functional nucleic acid, where the functional nucleic acid is selenium-derivatized nucleic acid.
FILED	Friday, November 21, 2014
APPL NO	15/038242
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) Original (OR) Class A61K 47/61 (20170801) Peptides C07K 1/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) Enzymes C12Y 301/26004 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101)
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10441820 — Systems and methods for opening of a tissue barrier in primates

US 10441820	Konofagou et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Institute on Aging (NIA) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Mental Health (NIMH) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	The Trustees of Columbia University in the Ciy of New York (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Elisa E. Konofagou (New York, New York); Fabrice Marquet (New York, New York); Yao-Sheng Tung (New York, New York)
ABSTRACT	Systems and methods for cavitation-guided opening of a targeted region of tissue within a primate skull are provided. In one example, a method includes delivering one or more microbubbles to proximate the targeted region, applying an ultrasound beam, using a transducer, through the skull of the primate to the targeted region to open the tissue, transcranially acquiring acoustic emissions produced from an interaction between the one or more microbubbles and the tissue, and determining a cavitation spectrum from the acquired acoustic emissions.
FILED	Tuesday, November 26, 2013
APPL NO	14/091010
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 8/481 (20130101) A61B 8/0808 (20130101) A61B 17/2258 (20130101) A61B 90/10 (20160201) A61B 2017/00106 (20130101) A61B 2017/22008 (20130101) A61B 2017/22089 (20130101) A61B 2090/378 (20160201) A61B 2503/40 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0039 (20130101)
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10441999 — Ultrasonic grain refining

US 10441999	Han et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	HANS TECH, LLC (West Lafayette, Indiana)
ASSIGNEE(S)	HANS TECH, LLC (West Lafayette, Indiana)
INVENTOR(S)	Qingyou Han (West Lafayette, Indiana); Lu Shao (West Lafayette, Indiana); Clause Xu (West Lafayette, Indiana)
ABSTRACT	A molten metal processing device including a molten metal containment structure for reception and transport of molten metal along a longitudinal length thereof. The device further includes a cooling unit for the containment structure including a cooling channel for passage of a liquid medium therein, and an ultrasonic probe disposed in relation to the cooling channel such that ultrasonic waves are coupled through the liquid medium in the cooling channel and through the molten metal containment structure into the molten metal.
FILED	Monday, October 10, 2016
APPL NO	15/289735
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 1/007 (20130101) B22D 11/003 (20130101) B22D 11/22 (20130101) B22D 11/103 (20130101) B22D 11/114 (20130101) B22D 11/117 (20130101) B22D 11/141 (20130101) B22D 11/144 (20130101) B22D 21/007 (20130101) B22D 27/08 (20130101) Original (OR) Class B22D 30/00 (20130101) B22D 35/04 (20130101) B22D 35/06 (20130101) B22D 37/00 (20130101)
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10442166 — Hydrophilic, yet slippery solid surfaces

US 10442166	Kota et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Science Foundation (NSF)
APPLICANT(S)	Colorado State University Research Foundation (Fort Collins, Colorado)
ASSIGNEE(S)	Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S)	Arun K. Kota (Fort Collins, Colorado); Hamed Vahabi (Fort Collins, Colorado)
ABSTRACT	In this work, a hydrophilic, yet slippery solid surface was developed. Because the surfaces are hydrophilic, there is significant affinity between the surface and contacting water, which results in substantial spreading of the contacting liquids on the surface. Due to their strong affinity, a high solid-liquid adhesion having virtually no mobility of the water on the surface occurs. However, counter-intuitively, the disclosed surfaces are highly slippery such that liquids can slide on the surface while maintaining their hydrophilicity. Demonstrated herein are water droplets that can slide on the surface under its own weight, when the hydrophilic, yet slippery solid surface is slightly tilted (ω=3°). This indicates that the disclosed hydrophilic surfaces are slippery to water.
FILED	Friday, January 11, 2019
APPL NO	16/246136
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/08 (20130101) A61L 33/00 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/18 (20130101) B05D 3/10 (20130101) B05D 5/08 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/30 (20130101) B32B 27/08 (20130101) Original (OR) Class B32B 27/28 (20130101) B32B 27/283 (20130101) B32B 27/285 (20130101) B32B 2307/728 (20130101) B32B 2307/746 (20130101) B32B 2535/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/336 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) C08L 71/08 (20130101) C08L 83/04 (20130101) C08L 2203/02 (20130101)
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10442693 — Porous nanostructured polyimide networks and methods of manufacture

US 10442693	Leventis et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Aerogel Technologies, LLC (Glendale, Wisconsin)
ASSIGNEE(S)	Aerogel Technologies, LLC (Glendale, Wisconsin)
INVENTOR(S)	Nicholas Leventis (Rolla, Missouri); Chariklia Sotiriou-Leventis (Rolla, Missouri); Chakkaravarthy Chidambareswarapattar (Rolla, Missouri)
ABSTRACT	Porous three-dimensional networks of polyimide and porous three-dimensional networks of carbon and methods of their manufacture are described. For example, polyimide aerogels are prepared by mixing a dianhydride and a diisocyanate in a solvent comprising a pyrrolidone and acetonitrile at room temperature to form a sol-gel material and supercritically drying the sol-gel material to form the polyimide aerogel. Porous three-dimensional polyimide networks, such as polyimide aerogels, may also exhibit a fibrous morphology. Having a porous three-dimensional polyimide network undergo an additional step of pyrolysis may result in the three dimensional network being converted to a purely carbon skeleton, yielding a porous three-dimensional carbon network. The carbon network, having been derived from a fibrous polyimide network, may also exhibit a fibrous morphology.
FILED	Wednesday, July 19, 2017
APPL NO	15/654111
ART UNIT	1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/00 (20170801) C01B 32/30 (20170801) C01B 32/90 (20170801) Original (OR) Class C01B 32/956 (20170801) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/346 (20130101) C08G 18/3243 (20130101) C08G 18/7671 (20130101) C08G 73/1003 (20130101) C08G 73/1035 (20130101) C08G 73/1067 (20130101) C08G 2101/0091 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/28 (20130101) C08J 2201/0502 (20130101) C08J 2205/026 (20130101) C08J 2375/04 (20130101) Compositions of Macromolecular Compounds C08L 79/08 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/38 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101)
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10442696 — Shape-controlled cement hydrate synthesis and self-assembly

US 10442696	Shahsavari et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	WILLIAM MARSH RICE UNIVERSITY (Houston, Texas)
ASSIGNEE(S)	WILLIAM MARSH RICE UNIVERSITY (Houston, Texas)
INVENTOR(S)	Rouzbeh Shahsavari (Houston, Texas); Sakineh Ebrahimpourmoghaddam (Houston, Texas); Kenton Herbert Whitmire (Houston, Texas)
ABSTRACT	In some embodiments, the present disclosure pertains to methods of forming calcium-silicate-hydrate particles by mixing a calcium source with a silicate source. In some embodiments, the mixing comprises sonication. In some embodiments, the mixing occurs in the presence of a surfactant and a solvent. In some embodiments, the methods of the present disclosure further comprise a step of controlling the morphology of the calcium-silicate-hydrate particles. In some embodiments, the step of controlling the morphology of calcium-silicate-hydrate particles comprises selecting a stoichiometric ratio of the calcium source over the silicate source. In some embodiments, the formed calcium-silicate-hydrate particles have cubic shapes. In some embodiments, the formed calcium-silicate-hydrate particles have rectangular shapes. In some embodiments, the formed calcium-silicate-hydrate particles are in the form of self-assembled particles of controlled shapes. Additional embodiments of the present disclosure pertain to compositions that contain the calcium silicate-hydrate particles of the present disclosure.
FILED	Wednesday, May 06, 2015
APPL NO	15/309279
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 33/24 (20130101) Original (OR) Class Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 12/04 (20130101) C04B 12/04 (20130101) C04B 22/085 (20130101) C04B 24/16 (20130101) C04B 28/18 (20130101) C04B 28/18 (20130101) C04B 28/18 (20130101) C04B 28/18 (20130101) C04B 28/188 (20130101) C04B 38/103 (20130101) C04B 40/0021 (20130101) C04B 40/0021 (20130101) C04B 40/0021 (20130101) C04B 40/0028 (20130101) C04B 40/0028 (20130101) C04B 40/0028 (20130101) C04B 2103/40 (20130101) C04B 2103/402 (20130101) C04B 2103/404 (20130101) C04B 2103/404 (20130101)
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10442890 — Multifunctional degradable nanoparticles with control over size and functionalities

US 10442890	Harth et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Eva M. Harth (Houston, Texas); David J. Calkins (Nashville, Tennessee); Alice E. Van Der Ende (Antioch, Tennessee)
ABSTRACT	In one aspect, the invention relates to polymers, crosslinked polymers, functionalized polymers, nanoparticles, and functionalized nanoparticles and methods of making and using same. In one aspect, the invention relates to degradable polymers and degradable nanoparticles. In one aspect, the invention relates to methods of preparing degradable nanoparticles and, more specifically, methods of controlling particle size during the preparation of degradable nanoparticles. In one aspect, the degradable nanoparticles are useful for complexing, delivering, and releasing payloads, including pharmaceutically active payloads. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED	Monday, August 21, 2017
APPL NO	15/682278
ART UNIT	1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/5153 (20130101) A61K 47/58 (20170801) A61K 47/59 (20170801) A61K 47/593 (20170801) A61K 47/595 (20170801) A61K 49/0041 (20130101) A61K 49/0056 (20130101) A61K 49/0093 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/08 (20130101) C08G 63/78 (20130101) C08G 63/912 (20130101) Original (OR) Class
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10442911 — Dendritic macroporous hydrogels prepared by crystal templating

US 10442911	Zawko et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Scott Zawko (Austin, Texas); Christine Schmidt (Gainesville, Florida)
ABSTRACT	The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture into a vessel; allowing the cast mixture to dry to form an amorphous hydrogel film; seeding the cast mixture with a seed crystal of the crystallizable molecule; growing the crystallizable molecule into a crystal structure within the uncrosslinked polymer; crosslinking the polymer around the crystal structure under conditions in which the crystal structure within the crosslinked polymer is maintained; and dissolving the crystals within the crosslinked polymer to form the porous hydrogel.
FILED	Wednesday, February 07, 2018
APPL NO	15/890719
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/0023 (20130101) A61L 26/0095 (20130101) A61L 27/52 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0065 (20130101) Polysaccharides; Derivatives Thereof C08B 37/003 (20130101) C08B 37/0015 (20130101) C08B 37/0045 (20130101) C08B 37/0072 (20130101) C08B 37/0075 (20130101) C08B 37/0084 (20130101) Derivatives of Natural Macromolecular Compounds C08H 1/06 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 3/26 (20130101) C08J 3/28 (20130101) C08J 3/075 (20130101) C08J 3/242 (20130101) C08J 5/10 (20130101) C08J 5/18 (20130101) C08J 9/26 (20130101) Original (OR) Class C08J 2201/0424 (20130101) C08J 2205/04 (20130101) C08J 2205/022 (20130101) C08J 2207/10 (20130101) C08J 2305/00 (20130101) C08J 2305/04 (20130101) C08J 2305/08 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/21 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0083 (20130101) Compositions of Macromolecular Compounds C08L 5/00 (20130101) C08L 5/00 (20130101) C08L 5/00 (20130101) C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/06 (20130101) C08L 5/06 (20130101) C08L 5/08 (20130101) C08L 5/08 (20130101) C08L 5/10 (20130101) C08L 5/10 (20130101) C08L 5/10 (20130101) C08L 5/16 (20130101) C08L 89/06 (20130101)
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10443511 — Control of fuel flow for power generation based on DC link level

US 10443511	Ethier et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Dynamo Micropower Corporation (Somerville, Massachusetts)
ASSIGNEE(S)	Dynamo Micropower Corporation (Somerville, Massachusetts)
INVENTOR(S)	Jason How-Ring Ethier (Somerville, Massachusetts); Ivan Wang (Boston, Massachusetts); German Lakov (Brookline, Massachusetts)
ABSTRACT	A power generating unit, control unit and modular power generating system. A power generating unit includes an engine-generator set including an engine that produces mechanical power and a generator mechanically coupled to the engine. The generator converts the mechanical power to electrical power provided to a DC link. The control unit includes at least one controller configured to control fuel flow to the engine based on a voltage of the DC link.
FILED	Wednesday, February 21, 2018
APPL NO	15/901659
ART UNIT	2831 — Electrical Circuits and Systems
CURRENT CPC	Internal-combustion Piston Engines; Combustion Engines in General F02B 37/004 (20130101) F02B 41/10 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/10 (20130101) F02C 6/14 (20130101) F02C 9/42 (20130101) Original (OR) Class F02C 9/56 (20130101) Controlling Combustion Engines F02D 29/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/764 (20130101) F05D 2260/15 (20130101) F05D 2260/42 (20130101) F05D 2260/43 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/32 (20130101) H02J 7/1415 (20130101) Dynamo-electric Machines H02K 7/1815 (20130101) H02K 7/1823 (20130101) H02K 11/046 (20130101) H02K 11/0094 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/144 (20130101) Y02T 10/163 (20130101)
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10444069 — Imaging spectrometer with freeform surfaces

US 10444069	Rolland et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	University of Rochester (Rochester, New York)
ASSIGNEE(S)	University of Rochester (Rochester, New York)
INVENTOR(S)	Jannick P. Rolland (Pittsford, New York); Jacob Reimers (Homestead, Florida)
ABSTRACT	Expanded performance opportunities for imaging spectrometers are described using ϕ-polynomial freeform surfaces in reflective and diffractive optics. The imaging spectrometers are generally of a type that include an entrance aperture for admitting radiation over a range of wavelengths, a detector array, a primary reflective optic with optical power, a secondary reflective diffractive optic, and a tertiary reflective optic with optical power for collectively imaging the entrance aperture onto the detector array through a range of dispersed positions. One or more of the primary reflective optic, the secondary reflective diffractive optic, and the tertiary reflective optic can include a ϕ-polynomial optical surface with no axis of symmetry and represented by a function that depends on both a radial component and an azimuthal component.
FILED	Tuesday, June 07, 2016
APPL NO	15/579201
ART UNIT	2886 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/18 (20130101) G01J 3/021 (20130101) Original (OR) Class G01J 3/0208 (20130101) G01J 3/2823 (20130101)
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10444187 — System and method for electrical characterization of electrical materials

US 10444187	Grayson et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Matthew Grayson (Evanston, Illinois); Jiajun Luo (Evanston, Illinois)
ABSTRACT	Systems and methods can provide a fast and accurate way to measure conductivity and Hall effect, such that transient conductivities, transient carrier densities or transient mobilities can be measured on millisecond time scales, for example. The systems and methods can also reduce the minimum magnetic field needed to extract carrier density or mobility of a given sample, and reduce the minimum mobility that can be measured with a given magnetic field.
FILED	Wednesday, August 30, 2017
APPL NO	15/690624
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/72 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 15/202 (20130101) G01R 19/08 (20130101) G01R 31/2648 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/11 (20130101) H05K 2201/032 (20130101)
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10444216 — Measuring concentration of analytes in liquid samples using surface-enhanced Raman spectroscopy

US 10444216	Peterman et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	OndaVia, Inc. (Hayward, California)
ASSIGNEE(S)	ONDAVIA, INC. (Hayward, California)
INVENTOR(S)	Mark Charles Peterman (Freemont, California); Merwan Benhabib (San Francisco, California); Carlos Atico Ariza (Hayward, California); Samuel Louis Kleinman (Oakland, California)
ABSTRACT	A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port and a cartridge for input to the cartridge receiving port. An optical detection system in the housing is capable of providing an illuminated electric field useful for Raman spectroscopy. The cartridge may have a sample well. The sample well is loaded with a mixture of water containing the analyte, Raman-scattering nanoparticles and a calibration solution. The calibration solution contains an analog of the analyte differing in its Raman response, for example an isotope of the analyte. Optionally, a chemical compound capable of increasing interaction between the analyte and the nanoparticles may be added.
FILED	Wednesday, November 22, 2017
APPL NO	15/821098
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) G01N 33/18 (20130101) Original (OR) Class G01N 33/182 (20130101)
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10444279 — Non-invasive pre-bond TSV test using ring oscillators and multiple voltage levels

US 10444279	Chakrabarty et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	DUKE UNIVERSITY (Durham, North Carolina)
ASSIGNEE(S)	DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S)	Krishnendu Chakrabarty (Chaphel Hill, North Carolina); Sergej Deutsch (Durham, North Carolina)
ABSTRACT	A design for test (DfT) architecture is provided that enables pre-bond parametric testing of through-silicon vias (TSVs). A grouping of N number of input/output (I/O) segments are configured to receive a test signal in a feedback loop, where each I/O segment includes one or more buffers (or inverters) and a TSV connected at one end to the one or more buffers. The TSV acts as a shunt-connected capacitor—when defect free—and includes a load resistance when the TSV contains a defect. Each I/O segment can also include one or two multiplexers to control whether the I/O segment receives a test or functional signal and, optionally, whether the I/O segment is bypassed or included in the ring oscillator. The varying loads caused by the defects cause variations in the delay across the buffers (or inverters) of an I/O segment that can be detected in the output signal.
FILED	Thursday, September 15, 2016
APPL NO	15/266744
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2601 (20130101) G01R 31/2853 (20130101) Original (OR) Class G01R 31/2894 (20130101) G01R 31/318558 (20130101)
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10444431 — Reticulated resonator, process for making and use of same

US 10444431	Simmonds et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Physics (PHY)
APPLICANT(S)	NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland); Cindy Regal (Boulder, Colorado); Pen-Li Yu (West Lafayette, Indiana); Yeghishe Tsaturyan (Copenhagen, Denmark); Thomas P. Purdy (Boulder, Colorado); Nir Shlomo Kampel (Boulder, Colorado)
ASSIGNEE(S)	NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland)
INVENTOR(S)	Raymond W. Simmonds (Boulder, Colorado); Katarina Cicak (Boulder, Colorado); Cindy A. Regal (Boulder, Colorado); Pen-Li Yu (West Lafayette, Indiana); Yeghishe Tsaturyan (Copenhagen, Denmark); Thomas P. Purdy (Gaithersburg, Maryland); Nir S. Kampel (Boulder, Colorado)
ABSTRACT	A reticulated resonator includes: a reticulated substrate that includes: a substrate frame; and a phononic structure in mechanical communication with the substrate frame and including a plurality of unit members arranged in a two-dimensional array; and a membrane disposed on the reticulated substrate. A process for producing a membrane frequency includes: providing a reticulated resonator including: a substrate frame; a phononic structure including: a first link connected to the substrate frame; a plurality of unit members arranged in a two-dimensional array and connected to the first link and in mechanical communication with the substrate frame through the first link; and a second link connected to the unit members; a membrane frame connected to the second link and in mechanical communication with the unit members through the second link; and a membrane disposed on the membrane and in mechanical communication with the substrate frame through the membrane frame and the unit members; subjecting the membrane to an excitation frequency; receiving, by the membrane, the excitation frequency; and producing, by the membrane, a membrane mode including a membrane frequency in response to receiving the excitation frequency.
FILED	Thursday, January 14, 2016
APPL NO	14/995853
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Optical Elements, Systems, or Apparatus G02B 6/1225 (20130101) Original (OR) Class
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10446234 — Self-powered timers and methods of use

US 10446234	Chakrabartty et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	WASHINGTON UNIVERSITY (St. Louis, Missouri)
ASSIGNEE(S)	Washington University (St. Louis, Missouri)
INVENTOR(S)	Shantanu Chakrabartty (St. Louis, Missouri); Liang Zhou (St. Louis, Missouri)
ABSTRACT	A timer module including a timer and a compensation circuit coupled to the timer is provided. The timer measures time over a first monitoring period. The timer includes a floating-gate and an energy barrier. The floating-gate stores electrons and has an initial state and a measured state. The measured state includes a current time and a current floating-gate voltage. The energy barrier is positioned adjacent the floating-gate and leaks electrons from an ambient environment of the timer to the floating-gate at a predetermined leakage rate using Fowler-Nordheim (FN) tunneling. The compensation circuit selectably adjusts the first monitoring period to facilitate improved robustness of the timer with respect to fabrication mismatch due to the self-compensating dynamics of FN tunneling.
FILED	Tuesday, October 24, 2017
APPL NO	15/792222
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Time-interval Measuring G04F 10/10 (20130101) Static Stores G11C 7/04 (20130101) G11C 16/04 (20130101) Original (OR) Class G11C 16/0408 (20130101) G11C 16/0441 (20130101) G11C 27/005 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/0629 (20130101) H01L 27/11526 (20130101) H01L 28/40 (20130101)
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10446329 — Process of forming electrodes and products thereof from biomass

US 10446329	Li et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S)	UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
INVENTOR(S)	Xiaodong Li (Charlottesville, Virginia); Zan Gao (Charlottesville, Virginia); Yunya Zhang (Charlottesville, Virginia)
ABSTRACT	A flexible electrode comprises an activated cotton textile composite comprising activated carbon fibers, nickel sulfide nanoparticles and graphene and a process for making the flexible electrode. The process may comprise preparing a cotton textile containing Ni(NO₃)₂. Then, the cotton textile containing Ni(NO₃)₂may be heated at a first temperature to produce an activated cotton textile composite comprising activated carbon fibers, nickel nanoparticles and graphene. The activated cotton textile composite may be then treated with sulfur to produce an activated cotton textile composite comprising activated carbon fibers, nickel sulfide nanoparticles and graphene. The nickel sulfide particles may be NiS₂nanoparticles in a form of nanobowls, and distributed on a surface and inside the activated carbon fibers. The activated carbon fibers and the nickel sulfide nanoparticles may be coated with graphene. Banana peels may be activated and treated with the similar processes to form electrodes for both supercapacitor and battery applications.
FILED	Friday, September 23, 2016
APPL NO	15/274557
ART UNIT	1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/26 (20130101) Original (OR) Class H01G 11/36 (20130101) H01G 11/40 (20130101) H01G 11/46 (20130101) H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/0416 (20130101) H01M 4/0471 (20130101) H01M 4/625 (20130101) H01M 4/5815 (20130101) H01M 4/5825 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101)
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10446852 — Fuel-cell system and method of generating energy from crude fuel

US 10446852	Li et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S)	Wenzhen Li (Ames, Iowa); Neeva Benipal (Ames, Iowa); Ji Qi (Ames, Iowa); Yang Qiu (Ames, Iowa)
ABSTRACT	The present invention relates to a fuel-cell system. This system includes an anode electrode; a cathode electrode; a separator positioned between the anode electrode and the cathode electrode, wherein the separator is not an ion exchange membrane; an anode catalyst; and a cathode catalyst, wherein the cathode catalyst is a non-precious metal catalyst or metal-free catalyst. The present invention also relates to a method of generating energy from crude fuel. This method involves providing a fuel-cell system and contacting the fuel-cell system with a crude fuel under conditions effective to generate energy from the crude fuel.
FILED	Tuesday, March 14, 2017
APPL NO	15/458202
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/96 (20130101) H01M 4/926 (20130101) Original (OR) Class H01M 4/9041 (20130101) H01M 4/9083 (20130101) H01M 8/0239 (20130101) H01M 8/1009 (20130101)
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10447038 — Microgrids with dynamically configurable boundaries including multiple main grid feeder coupling locations and methods of operating the same

US 10447038	Wang et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S)	University of Tennessee Research (Knoxville, Tennessee)
INVENTOR(S)	Fei Wang (Knoxville, Tennessee); Xiaojie Shi (Knoxville, Tennessee); Leon M. Tolbert (Knoxville, Tennessee); Yiwei Ma (Knoxville, Tennessee); Yilu Liu (Knoxville, Tennessee); Lin Zhu (Knoxville, Tennessee)
ABSTRACT	An energy system includes a microgrid including a network of at least one distributed energy resource and a plurality of loads, the at least one distributed energy resource being configured to supply power to the plurality of loads. The microgrid is configurable to connect to one of a plurality of feeder circuits of a main power grid at one of a plurality of coupling interface locations, respectively. The microgrid is also configurable to expand or shrink its power supply area according to the available power generation capabilities.
FILED	Friday, November 10, 2017
APPL NO	15/809329
ART UNIT	2117 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/14 (20130101) Original (OR) Class H02J 3/381 (20130101) H02J 13/0017 (20130101)
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10447249 — Hold violation free scan chain and scanning mechanism for testing of synchronous digital VLSI circuits

US 10447249	Vrudhula et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Sarma Vrudhula (Chandler, Arizona); Niranjan Kulkarni (Tempe, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Sarma Vrudhula (Chandler, Arizona); Niranjan Kulkarni (Tempe, Arizona)
ABSTRACT	A sequential state element (SSE) is disclosed. In one embodiment, an SSE includes a differential sense flip flop (DSFF) and a completion detection circuit (CDC) operably associated with the DSFF. The DSFF is configured to generate a differential logical output. During a normal operational mode, the DSFF is synchronized by a clock signal to provide a differential logical output in a differential output state in accordance with a data input or in a precharge state based on the clock signal. The differential logical output is provided in a differential output state in accordance with a test input during a scan mode. The CDC is configured to generate a test enable input during the scan mode that indicates the scan mode once the differential logical output is in the differential output state. Accordingly, another SSE can be asynchronously triggered to operate in the scan mode without a separate scan clock.
FILED	Monday, May 23, 2016
APPL NO	15/568858
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3177 (20130101) G01R 31/318541 (20130101) Pulse Technique H03K 3/0375 (20130101) H03K 3/356086 (20130101) Original (OR) Class
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10447318 — Low power high gain radio frequency amplifier for sensor apparatus

US 10447318	Blaauw et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	The Regents of The University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	David T. Blaauw (Ann Arbor, Michigan); David D. Wentzloff (Ann Arbor, Michigan); Li-Xuan Chuo (Ann Arbor, Michigan); Hun-Seok Kim (Ann Arbor, Michigan)
ABSTRACT	A wireless communication device is presented for use with a sensor. The wireless communication device includes: an antenna, a driver circuit and a bias circuit. The driver circuit is electrically coupled to the antenna and includes at least one pair of cross-coupled transistors. The bias circuit is electrically coupled to the driver circuit. In a transmit mode, the bias circuit biases the driver circuit with a first bias current. In response to the first bias current, the driver circuit oscillates the antenna. In a receive mode, the bias circuit biases the driver circuit with a second bias current, such that the first bias current differs from the second bias current. In response to the second bias current, the bias circuit amplifies a signal received by the antenna.
FILED	Friday, February 02, 2018
APPL NO	15/887212
ART UNIT	2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 7/00 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/1212 (20130101) H03B 5/1228 (20130101) H03B 2200/0008 (20130101) H03B 2200/0082 (20130101) Transmission H04B 1/04 (20130101) Original (OR) Class H04B 1/40 (20130101)
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10447331 — Ambient backscatter transceivers, apparatuses, systems, and methods for communicating using backscatter of ambient RF signals

US 10447331	Gollakota et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	University of Washington (Seattle, Washington)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Shyamnath Gollakota (Seattle, Washington); Joshua R. Smith (Seattle, Washington); Vincent Liu (Seattle, Washington); Aaron N. Parks (Seattle, Washington); Vamsi Talla (Seattle, Washington)
ABSTRACT	Apparatuses, systems, ambient backscatter transceivers, and methods for modulating a backscatter of an ambient RF signal are described. An example system may include an ambient backscatter transceiver comprising an antenna that is configured to receive a backscattered ambient radio frequency (RF) signal. The ambient backscatter transceiver is configured to demodulate the backscattered ambient RF signal to retrieve first data. The backscattered ambient RF signal is generated by backscattering an ambient RF signal at a first frequency. The ambient RF signal is encoded with modulated to provide second data at a second frequency.
FILED	Tuesday, July 24, 2018
APPL NO	16/043383
ART UNIT	2633 — Digital Communications
CURRENT CPC	Transmission H04B 1/40 (20130101) Original (OR) Class
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10447410 — Ultrasonic communication system

US 10447410	Biswas et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S)	Subir Biswas (Okemos, Michigan); Stephan Lorenz (Lake Orion, Michigan); Bo Dong (Sunnyvale, California); Qiong Huo (Sunnyvale, California)
ABSTRACT	A sensor network includes a sink and multiple sensor nodes. The sink is coupled to a substrate and configured to transmit a periodic ultrasonic pulse on the substrate. A first one of the sensor nodes is coupled to the substrate. The first sensor node is configured to (i) receive the periodic ultrasonic pulse from the substrate, (ii) synchronize an internal clock of the first sensor node to the sink based on the periodic ultrasonic pulse, (iii) selectively detect an event in a region surrounding the first sensor node, and (iv) in response to detecting the event, transmit a first ultrasonic pulse toward the sink on the substrate.
FILED	Wednesday, November 26, 2014
APPL NO	15/039243
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 25/009 (20130101) Transmission H04B 11/00 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 7/02 (20130101) H04L 7/0037 (20130101) Wireless Communication Networks H04W 4/38 (20180201) H04W 4/70 (20180201) H04W 56/0015 (20130101)
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10448152 — Systems and methods for monitoring and classifying marine animals based on acoustic signals

US 10448152	Makris et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate of Geosciences (GEO) Division of Ocean Sciences (OCE)
APPLICANT(S)	Northeastern Univerisity (Boston, Massachusetts)
ASSIGNEE(S)	Northeastern University (Boston, Massachusetts)
INVENTOR(S)	Purnima Ratilal Makris (Boston, Massachusetts); Nicholas Constantine Makris (Boston, Massachusetts)
ABSTRACT	Disclosed herein are apparatus, devices, and methods for monitoring marine animals, such as whales, and other marine mammals, and fish groups within a marine environment. A marine animal monitoring system may include an acoustic receiver array having a high-resolution directional sensing capacity using large-aperture densely-sampled coherent ocean acoustic receiver arrays operative to enhance detection range and localization accuracy of marine mammal vocalizations and fish acoustic signals. The acoustic receiver array may generate acoustic signal information based on acoustic signals sensed at the array. The marine monitoring system may operate to generate marine animal information based on the acoustic signal information, such as marine animal location, species, call type, and/or the like.
FILED	Wednesday, September 21, 2016
APPL NO	15/271890
ART UNIT	2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC	Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 17/26 (20130101) G10L 25/51 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/44 (20130101) Original (OR) Class H04R 1/265 (20130101) H04R 3/005 (20130101) H04R 29/008 (20130101) H04R 2430/03 (20130101) H04R 2430/20 (20130101)
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National Security Agency (NSA)

10445098 — Processors and methods for privileged configuration in a spatial array

US 10445098	Fleming et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	INTEL CORPORATION (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Kermin E. Fleming (Hudson, Massachusetts); Simon C. Steely (Hudson, New Hampshire); Kent D. Glossop (Merrimack, New Hampshire)
ABSTRACT	Methods and apparatuses relating to privileged configuration in spatial arrays are described. In one embodiment, a processor includes processing elements; an interconnect network between the processing elements; and a configuration controller coupled to a first subset and a second, different subset of the plurality of processing elements, the first subset having an output coupled to an input of the second, different subset, wherein the configuration controller is to configure the interconnect network between the first subset and the second, different subset of the plurality of processing elements to not allow communication on the interconnect network between the first subset and the second, different subset when a privilege bit is set to a first value and to allow communication on the interconnect network between the first subset and the second, different subset of the plurality of processing elements when the privilege bit is set to a second value.
FILED	Saturday, September 30, 2017
APPL NO	15/721809
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 9/544 (20130101) G06F 9/3017 (20130101) Original (OR) Class G06F 9/3895 (20130101) G06F 9/5016 (20130101)
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10445234 — Processors, methods, and systems for a configurable spatial accelerator with transactional and replay features

US 10445234	Fleming et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Kermin Fleming (Hudson, Massachusetts); Kent D. Glossop (Merrimack, New Hampshire); Simon C. Steely, Jr. (Hudson, New Hampshire); Samantika S. Sury (Westford, Massachusetts)
ABSTRACT	Systems, methods, and apparatuses relating to a configurable spatial accelerator are described. In an embodiment, a processor includes a plurality of processing elements; and an interconnect network between the plurality of processing elements to receive an input of a dataflow graph comprising a plurality of nodes, wherein the dataflow graph is to be overlaid into the interconnect network and the plurality of processing elements with each node represented as a dataflow operator in the plurality of processing elements, and the plurality of processing elements are to perform an atomic operation when an incoming operand set arrives at the plurality of processing elements.
FILED	Saturday, July 01, 2017
APPL NO	15/640533
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 12/0802 (20130101) Original (OR) Class G06F 15/7867 (20130101) G06F 15/8015 (20130101) G06F 17/505 (20130101) Static Stores G11C 7/1012 (20130101) G11C 8/12 (20130101) G11C 2207/2245 (20130101) Pulse Technique H03K 19/1776 (20130101) H03K 19/1778 (20130101) H03K 19/17736 (20130101) H03K 19/17756 (20130101) H03K 19/17764 (20130101) H03K 19/17776 (20130101)
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10445250 — Apparatus, methods, and systems with a configurable spatial accelerator

US 10445250	Fleming et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Kermin E. Fleming (Hudson, Massachusetts); Kent D. Glossop (Merrimack, New Hampshire); Simon C. Steely (Hudson, New Hampshire)
ABSTRACT	Systems, methods, and apparatuses relating to a configurable spatial accelerator are described. In one embodiment, a processor includes a core with a decoder to decode an instruction into a decoded instruction and an execution unit to execute the decoded instruction to perform a first operation; a plurality of processing elements; and an interconnect network between the plurality of processing elements to receive an input of a dataflow graph comprising a plurality of nodes, wherein the dataflow graph is to be overlaid into the interconnect network and the plurality of processing elements with each node represented as a dataflow operator in the plurality of processing elements, and the plurality of processing elements are to perform a second operation by a respective, incoming operand set arriving at each of the dataflow operators of the plurality of processing elements.
FILED	Saturday, December 30, 2017
APPL NO	15/859454
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 12/1054 (20130101) Original (OR) Class G06F 2212/608 (20130101) G06F 2212/683 (20130101)
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10445451 — Processors, methods, and systems for a configurable spatial accelerator with performance, correctness, and power reduction features

US 10445451	Fleming et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Kermin Fleming (Hudson, Massachusetts); Kent D. Glossop (Merrimack, New Hampshire); Simon C. Steely, Jr. (Hudson, New Hampshire); Ping Tak Peter Tang (Edison, New Jersey)
ABSTRACT	Systems, methods, and apparatuses relating to a configurable spatial accelerator are described. In one embodiment, a processor includes a plurality of processing elements; and an interconnect network between the plurality of processing elements to receive an input of a dataflow graph comprising a plurality of nodes, wherein the dataflow graph is to be overlaid into the interconnect network and the plurality of processing elements with each node represented as a dataflow operator in the plurality of processing elements, and the plurality of processing elements is to perform an operation when an incoming operand set arrives at the plurality of processing elements. At least one of the plurality of processing elements includes a plurality of control inputs.
FILED	Saturday, July 01, 2017
APPL NO	15/640535
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 12/0802 (20130101) G06F 15/7867 (20130101) G06F 15/8015 (20130101) G06F 17/505 (20130101) Original (OR) Class Static Stores G11C 8/12 (20130101) Pulse Technique H03K 19/1778 (20130101) H03K 19/17736 (20130101) H03K 19/17756 (20130101) H03K 19/17764 (20130101) H03K 19/17776 (20130101)
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10445478 — Multi-user access control for a sensitive system

US 10445478	Barrick et al.
FUNDED BY	National Security Agency (NSA)
APPLICANT(S)	The Government of the United States as represented by the Director, National Security Agency (Fort George G. Meade, Maryland)
ASSIGNEE(S)	Government of the United States, as represented by Director, National Security Agency (Washington, District of Columbia)
INVENTOR(S)	Daniel M. Barrick (Eldersburg, Maryland); Raul Grajales, III (Pasadena, Maryland); Brian S. McGarvey (Arnold, Maryland); Mark S. Sitzwohl (Millersville, Maryland); William Paul F. Wright (Dayton, New Jersey)
ABSTRACT	A multi-user access control device provides controlled access to a sensitive system by enabling/disabling an input/output port in communication with said sensitive system. Tokens are held by users and provide for confirmation of group membership and authentication. Upon authentication of the users, an enable signal is provided to a relay providing power to an external port. The external port may provide power to an input/output device allowing the user to interact with the sensitive system. The external port may provide power to a network port of the access control device allowing for management of the access control device or allowing for auditing of the access control device.
FILED	Tuesday, August 15, 2017
APPL NO	15/677386
ART UNIT	2494 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 1/266 (20130101) G06F 1/3218 (20130101) G06F 1/3265 (20130101) G06F 13/4286 (20130101) G06F 21/31 (20130101) Original (OR) Class
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National Aeronautics and Space Administration (NASA)

10444180 — Polymer electrolyte-based sensors

US 10444180	Hunter et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Gary W Hunter (Oberlin, Ohio); Jennifer C Xu (Olmsted Township, Ohio); Chung-Chiun Liu (Cleveland Heights, Ohio)
ASSIGNEE(S)	United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Gary W Hunter (Oberlin, Ohio); Jennifer C Xu (Olmsted Township, Ohio); Chung-Chiun Liu (Cleveland Heights, Ohio)
ABSTRACT	A polymer electrolyte-based sensor is disclosed. The sensor includes a conductive polymer electrolyte film including water-retaining components. The water-retaining components facilitate operational conductivity of the conductive polymer electrolyte film in lower humidity environments than would be possible without the water-retaining components.
FILED	Thursday, July 19, 2012
APPL NO	13/552760
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/406 (20130101) Original (OR) Class G01N 27/407 (20130101)
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10444189 — Method and apparatus for non-destructive evaluation of materials

US 10444189	Goldfine et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	JENTEK Sensors, Inc. (Waltham, Massachusetts)
ASSIGNEE(S)	JENTEK Sensors, Inc. (Marlborough, Massachusetts)
INVENTOR(S)	Neil J Goldfine (Indian Harbour Beach, Florida); Andrew P Washabaugh (Chula Vista, California); Robert Lyons (Pelham, Massachusetts)
ABSTRACT	Methods and apparatus for characterizing composite materials for manufacturing quality assurance (QA), periodic inspection during the useful life, or for forensic analysis/material testing. System are provided that relate eddy-current sensor responses to the fiber layup of a composite structure, the presence of impact damage on a composite structure with or without a metal liner, volumetric stress within the composite, fiber tow density, and other NDE inspection requirements. Also provided are systems that determine electromagnetic material properties and material dimensions of composite materials from capacitive sensor inspection measurements. These properties are related to the presence of buried defects in non-conductive composite materials, moisture ingress, aging of the material due to service or environmental/thermal exposure, or changes in manufacturing quality.
FILED	Tuesday, July 11, 2017
APPL NO	15/646622
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/72 (20130101) G01N 27/90 (20130101) Original (OR) Class G01N 27/9046 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/10 (20130101) G01R 33/0064 (20130101) G01R 33/093 (20130101) G01R 33/0094 (20130101)
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10446373 — Cyclotronic plasma actuator with arc-magnet for active flow control

US 10446373	Zimmerman et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Langley Research Center (LaRC) NASA Shared Services Center (NSSC)
APPLICANT(S)	CU Aerospace, LLC (Champaign, Illinois); The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	CU Aerospace, LLC (Champaign, Illinois)
INVENTOR(S)	Joseph W. Zimmerman (Champaign, Illinois); David L. Carroll (Champaign, Illinois); Phillip J. Ansell (Urbana, Illinois); Georgi Hristov (Champaign, Illinois)
ABSTRACT	In an embodiment of the invention there is a cyclotronic actuator utilizing a high-voltage plasma driver connected to a first electrode. A second electrode is grounded and the two are isolated from each other by a dielectric plate. A magnet is positioned beneath the dielectric plate such that a coaxial dielectric barrier discharge plasma is formed outwardly between the first electrode across the dielectric plate. The magnet positioned beneath the dielectric plate introduces a magnetic field transverse to the plasma current path, such that the plasma discharge discharges radially and the local magnetic field is oriented vertically in a direction perpendicular to the dielectric plate to create a Lorentz Force, which forces the plasma discharge to move radially outwardly in a curved radial streamer mode pattern.
FILED	Thursday, April 18, 2019
APPL NO	16/387777
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Aeroplanes; Helicopters B64C 23/005 (20130101) B64C 2230/12 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/32064 (20130101) Original (OR) Class H01J 37/32449 (20130101) H01J 37/32568 (20130101) H01J 37/32678 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/1563 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/50 (20130101)
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10446920 — Aerogel-based antennas for aerospace and terrestrial applications

US 10446920	Meador et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Mary Ann B. Meador (Strongsville, Ohio); Felix A. Miranda (Olmsted Falls, Ohio); Frederick W. Van Keuls (Westlake, Ohio)
ABSTRACT	Systems and methods for lightweight, customizable antenna with improved performance and mechanical properties are disclosed. In some aspects, aerogels can be used, for example, as a substrate for antenna fabrication. The reduced weight and expense, as well as the increased ability to adapt antenna designs, permits a systems to mitigate a variety of burdens associated with antennas while providing added benefits.
FILED	Monday, April 11, 2016
APPL NO	15/095894
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/28 (20130101) H01Q 1/32 (20130101) H01Q 1/38 (20130101) Original (OR) Class H01Q 1/085 (20130101) H01Q 1/273 (20130101) H01Q 21/0087 (20130101)
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Department of Agriculture (USDA)

10440911 — Targeted modification of maize roots to enhance abiotic stress tolerance

US 10440911	Kaeppler et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Organismal Systems (IOS) Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Penn State Research Foundation (University Park, Pennsylvania); The University of Nottingham (East Midlands, United Kingdom)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Shawn Michael Kaeppler (Oregon, Wisconsin); Patompong Saengwilai (Bangkok, Thailand); Jonathan Paul Lynch (Boalsburg, Pennsylvania); Malcolm John Bennett (Nottingham, United Kingdom); James Johnson (Whitestown, Indiana)
ABSTRACT	The present invention relates to crop breeding. More particularly, the present invention relates to targeted modification of root to enhance abiotic stress tolerance in maize. In one aspect, the invention provides recombinant maize exhibiting increased root cortical aerenchyma (RCA). Methods of making the recombinant maize and various methods of plant selection and breeding are further provided.
FILED	Thursday, September 14, 2017
APPL NO	15/704502
ART UNIT	1663 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/06 (20130101) A01H 5/10 (20130101) Original (OR) Class A01H 6/4684 (20180501) Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/82 (20130101) C12N 15/8242 (20130101) C12N 15/8271 (20130101)
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10443010 — Polytriglycerides

US 10443010	Harry O Kuru et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Rogers E. Harry O Kuru (Peoria, Illinois); Girma Biresaw (Peoria, Illinois); Rex E. Murray (Peoria, Illinois)
ABSTRACT	Disclosed herein are polyketone triglyceride compositions containing 8 to 16 ketone carbonyl moieties per triglyceride unit and methods of making. Also disclosed are polyimine triglyceride compositions having has 8 to 16 nitrogen moieties per triglyceride unit and methods of making. Also disclosed are polyamine triglyceride compositions containing 8 to 16 nitrogen moieties per triglyceride unit and methods of making.
FILED	Thursday, September 21, 2017
APPL NO	15/711509
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 69/716 (20130101) Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 105/20 (20130101) C10M 105/56 (20130101) C10M 105/60 (20130101) C10M 129/95 (20130101) C10M 133/06 (20130101) C10M 133/22 (20130101) C10M 133/54 (20130101) Original (OR) Class C10M 159/12 (20130101) C10M 177/00 (20130101) C10M 2207/34 (20130101) C10M 2207/40 (20130101) C10M 2207/401 (20130101) C10M 2215/003 (20130101) C10M 2215/04 (20130101) C10M 2215/14 (20130101) C10M 2215/041 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2230/02 (20130101) C10N 2230/06 (20130101) C10N 2230/14 (20130101) C10N 2260/02 (20130101) C10N 2260/04 (20130101) C10N 2270/00 (20130101) Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom C11C 3/006 (20130101)
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Department of Commerce (DOC)

10444431 — Reticulated resonator, process for making and use of same

US 10444431	Simmonds et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Physics (PHY)
APPLICANT(S)	NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland); Cindy Regal (Boulder, Colorado); Pen-Li Yu (West Lafayette, Indiana); Yeghishe Tsaturyan (Copenhagen, Denmark); Thomas P. Purdy (Boulder, Colorado); Nir Shlomo Kampel (Boulder, Colorado)
ASSIGNEE(S)	NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland)
INVENTOR(S)	Raymond W. Simmonds (Boulder, Colorado); Katarina Cicak (Boulder, Colorado); Cindy A. Regal (Boulder, Colorado); Pen-Li Yu (West Lafayette, Indiana); Yeghishe Tsaturyan (Copenhagen, Denmark); Thomas P. Purdy (Gaithersburg, Maryland); Nir S. Kampel (Boulder, Colorado)
ABSTRACT	A reticulated resonator includes: a reticulated substrate that includes: a substrate frame; and a phononic structure in mechanical communication with the substrate frame and including a plurality of unit members arranged in a two-dimensional array; and a membrane disposed on the reticulated substrate. A process for producing a membrane frequency includes: providing a reticulated resonator including: a substrate frame; a phononic structure including: a first link connected to the substrate frame; a plurality of unit members arranged in a two-dimensional array and connected to the first link and in mechanical communication with the substrate frame through the first link; and a second link connected to the unit members; a membrane frame connected to the second link and in mechanical communication with the unit members through the second link; and a membrane disposed on the membrane and in mechanical communication with the substrate frame through the membrane frame and the unit members; subjecting the membrane to an excitation frequency; receiving, by the membrane, the excitation frequency; and producing, by the membrane, a membrane mode including a membrane frequency in response to receiving the excitation frequency.
FILED	Thursday, January 14, 2016
APPL NO	14/995853
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Optical Elements, Systems, or Apparatus G02B 6/1225 (20130101) Original (OR) Class
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10446391 — Thick pseudomorphic nitride epitaxial layers

US 10446391	Grandusky et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	James R. Grandusky (Waterford, New York); Leo J. Schowalter (Latham, New York); Shawn R. Gibb (Clifton Park, New York); Joseph A. Smart (Mooresville, North Carolina); Shiwen Liu (Painted Post, New York)
ASSIGNEE(S)	CRYSTAL IS, INC. (Green Island, New York)
INVENTOR(S)	James R. Grandusky (Waterford, New York); Leo J. Schowalter (Latham, New York); Shawn R. Gibb (Clifton Park, New York); Joseph A. Smart (Mooresville, North Carolina); Shiwen Liu (Painted Post, New York)
ABSTRACT	In various embodiments, a semiconductor device includes an aluminum nitride single-crystal substrate, a pseudomorphic strained layer disposed thereover that comprises at least one of AlN, GaN, InN, or an alloy thereof, and, disposed over the strained layer, a semiconductor layer that is lattice-mismatched to the substrate and substantially relaxed.
FILED	Thursday, November 17, 2011
APPL NO	13/298570
ART UNIT	2815 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) Original (OR) Class H01L 21/0262 (20130101) H01L 21/02389 (20130101) H01L 21/02433 (20130101) H01L 21/02458 (20130101) H01L 33/08 (20130101) H01L 33/12 (20130101) H01L 33/20 (20130101) H01L 33/22 (20130101) H01L 33/025 (20130101) H01L 33/32 (20130101)
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Department of Justice (DOJ)

10445555 — Systems and methods for ridge-based fingerprint analysis

US 10445555	Walch et al.
FUNDED BY	Department of Justice (DOJ) Federal Bureau of Investigation (FBI)
APPLICANT(S)	Mark A. Walch (Chantilly, Virginia); Donald T. Gantz (Fairfax, Virginia); Daniel Thomas Gantz (Arlington, Virginia)
ASSIGNEE(S)	SCIOMETRICS, LLC (Chantilly, Virginia)
INVENTOR(S)	Mark A. Walch (Chantilly, Virginia); Donald T. Gantz (Fairfax, Virginia); Daniel Thomas Gantz (Arlington, Virginia)
ABSTRACT	In an automated method of processing fingerprint images, identity information is extracted from prints typically classified as having “no identification value” because of sparse or missing minutiae by capturing ridge information. Bezier approximations of ridge curvature are used as Ridge Specific Markers. Control points arising from Bezier curves generate unique polygons that represent the actual curve in the fingerprint. These polygons are generated for latent prints and reference prints and compared to determine whether a match exists.
FILED	Monday, February 06, 2012
APPL NO	13/367153
ART UNIT	2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/001 (20130101) G06K 9/0008 (20130101) G06K 9/00093 (20130101) Original (OR) Class G06K 2209/01 (20130101)
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10445565 — Crowd analytics via one shot learning

US 10445565	Tu et al.
FUNDED BY	Department of Justice (DOJ) Office of Justice Programs (OJP) National Institute of Justice (NIJ)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	GENERAL ELECTRIC COMPANY (Niskayuna, New York)
INVENTOR(S)	Peter Henry Tu (Niskayuna, New York); Tao Gao (Niskayuna, New York); Jilin Tu (Schenectady, New York)
ABSTRACT	Provided are techniques for assessing individual or crowd level behavior based on image data analysis. For example, in one embodiment, the techniques may include generating signatures representative of an observed behavior based on video data and performing pairwise matching by determining whether the first signature matches a second signature indicative of a query behavior.
FILED	Tuesday, December 06, 2016
APPL NO	15/370746
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0061 (20130101) G06K 9/00315 (20130101) G06K 9/00335 (20130101) Original (OR) Class G06K 9/00342 (20130101) G06K 9/00758 (20130101) G06K 9/00771 (20130101) G06K 9/00778 (20130101) Image Data Processing or Generation, in General G06T 7/248 (20170101) G06T 2207/30201 (20130101) G06T 2207/30232 (20130101) Pictorial Communication, e.g Television H04N 7/183 (20130101)
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Department of Transportation (USDOT)

10443447 — Doubler attachment system

US 10443447	King et al.
FUNDED BY	Department of Transportation (USDOT) Federal Aviation Administration (FAA)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Daniel Elmer King (Norwood, Ohio); Jonathan Harry Kerner (Brookline, Massachusetts)
ABSTRACT	A doubler attachment system is provided for fixedly coupling a strut to an engine casing. The strut includes at least one flanged end configured to mate with the engine casing. The doubler attachment system includes a doubler plate having a first radial surface and a second opposing radial surface. The first radial surface is configured to mate with and conform to a contour of the at least one flanged end of the strut. The doubler attachment system further includes at least two bolts fixedly attached to the doubler plate at the first radial surface. The at least two bolts extend radially away from the first radial surface and toward the engine casing.
FILED	Monday, March 14, 2016
APPL NO	15/068682
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/042 (20130101) F01D 25/162 (20130101) F01D 25/243 (20130101) Original (OR) Class F01D 25/246 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/20 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101)
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10446859 — Fuel cell gas inlet manifold drain

US 10446859	Skiba et al.
FUNDED BY	Department of Transportation (USDOT)
APPLICANT(S)	Tommy Skiba (East Hartford, Connecticut); Christopher John Carnevale (Vernon, Connecticut)
ASSIGNEE(S)	AUDI AG (Ingolstadt, Germany)
INVENTOR(S)	Tommy Skiba (East Hartford, Connecticut); Christopher John Carnevale (Vernon, Connecticut)
ABSTRACT	An exemplary manifold assembly includes a gas inlet manifold configured to introduce a gas to a fuel cell. A gas outlet manifold is configured to direct gas away from the fuel cell. A drain channel connects the inlet manifold to the outlet manifold. The drain channel is configured to carry liquid from the gas inlet manifold to the gas outlet manifold.
FILED	Thursday, May 24, 2012
APPL NO	14/403146
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/2485 (20130101) H01M 8/04156 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

10444216 — Measuring concentration of analytes in liquid samples using surface-enhanced Raman spectroscopy

US 10444216	Peterman et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	OndaVia, Inc. (Hayward, California)
ASSIGNEE(S)	ONDAVIA, INC. (Hayward, California)
INVENTOR(S)	Mark Charles Peterman (Freemont, California); Merwan Benhabib (San Francisco, California); Carlos Atico Ariza (Hayward, California); Samuel Louis Kleinman (Oakland, California)
ABSTRACT	A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port and a cartridge for input to the cartridge receiving port. An optical detection system in the housing is capable of providing an illuminated electric field useful for Raman spectroscopy. The cartridge may have a sample well. The sample well is loaded with a mixture of water containing the analyte, Raman-scattering nanoparticles and a calibration solution. The calibration solution contains an analog of the analyte differing in its Raman response, for example an isotope of the analyte. Optionally, a chemical compound capable of increasing interaction between the analyte and the nanoparticles may be added.
FILED	Wednesday, November 22, 2017
APPL NO	15/821098
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) G01N 33/18 (20130101) Original (OR) Class G01N 33/182 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10448143 — Wireless communications headset system employing a loop transmitter that fits around the pinna

US 10448143	Parkins
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Red Tail Hawk Corporation (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Red Tail Hawk Corporation (Philadelphia, Pennsylvania)
INVENTOR(S)	John W. Parkins (Ithaca, New York)
ABSTRACT	A wireless communications headset system for double hearing protection systems that eliminates the problems associated with typical wireless communications systems. The system employs a magnetic-field coupled wireless link from a loop transmitter to a magnetic field receiver. Current through the transmitter wire loops generates magnetic flux which passes through a communications earplug. The earplug has a receiver for converting the magnetic flux to electrical voltage, and this voltage is used to drive a speaker within the earplug. The transmitter can be easily installed into aviation headsets. The loop transmitter has an open center sized so that it fits around the pinna of the human ear enabling a close position to the communications earplug. This close position is advantageous if an efficient system is desired.
FILED	Tuesday, April 26, 2016
APPL NO	15/138603
ART UNIT	2656 — Digital Audio Data Processing
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 11/08 (20130101) A61F 11/14 (20130101) Antennas, i.e Radio Aerials H01Q 1/273 (20130101) H01Q 7/08 (20130101) Telephonic Communication H04M 1/05 (20130101) H04M 1/215 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/08 (20130101) H04R 1/1016 (20130101) H04R 1/1083 (20130101) H04R 1/1091 (20130101) Original (OR) Class H04R 3/04 (20130101) H04R 2201/107 (20130101) H04R 2420/07 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of the Treasury (TREASURY)

10445078 — Layered software architecture model for translation of assembler language to target language

US 10445078	Wang et al.
FUNDED BY	Department of the Treasury (TREASURY) Internal Revenue Service (IRS)
APPLICANT(S)	Jian Wang (Sterling, Virginia); Zhenqiang Yu (Rockville, Maryland); Yan Cheng (Great Falls, Virginia)
ASSIGNEE(S)	Internal Revenue Service United States Department of the Treasury (, None)
INVENTOR(S)	Jian Wang (Sterling, Virginia); Zhenqiang Yu (Rockville, Maryland); Yan Cheng (Great Falls, Virginia)
ABSTRACT	The present invention is a multi-layer computer architecture which separately extracts ALC business and logical functions and data. The architecture creates a Java object model or other target language object model which allows comparison of ALC data with target language data to verify logical processes. These object models can be directly traced back to the legacy ALC. The data model is automatically generated from a scan of the ALC and leverages generic patterns which can be reused to generate Java representations of other legacy code bases.
FILED	Saturday, April 29, 2017
APPL NO	15/582619
ART UNIT	3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Electric Digital Data Processing G06F 8/433 (20130101) G06F 8/447 (20130101) Original (OR) Class G06F 9/45516 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

U.S. Agency for International Development (USAID)

10444232 — Diagnostic devices, systems, and methods

US 10444232	Guo et al.
FUNDED BY	U.S. Agency for International Development (USAID)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Tiffany Guo (Lagrange, Ohio); Samuel K. Sia (New York, New York); Jeisun Shi Xie (San Jose, California); Fanxing Meng (Tianjin, China PRC); Keith Yeager (Jersey City, New Jersey)
ABSTRACT	Diagnostic systems, methods, and devices employing low-cost handheld components are disclosed herein. A diagnostic system can include a diagnostic device that is configured to perform one or more assays on a fluid sample, such as a whole blood sample, in one or more microfluidic channels or chambers. The diagnostic device can move the fluid sample into or through the one or more microfluidic channels or chambers without using any electrical power, for example, using manual actuation to generate a positive or negative pressure within the diagnostic device. The diagnostic device can have a connector for interfacing with a separate handheld unit that can provide power and data processing. For example, the separate handheld unit can be a smartphone or PDA, and the connector can interface with an existing input/output port of the unit to draw power and/or transmit data.
FILED	Thursday, August 13, 2015
APPL NO	15/503512
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 2200/16 (20130101) B01L 2300/023 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2400/049 (20130101) B01L 2400/0481 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/66 (20130101) G01N 33/571 (20130101) G01N 33/6827 (20130101) G01N 33/54366 (20130101) Original (OR) Class G01N 33/56988 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

10442721 — Microgravity-based method and system for fabricating optical fibers

US 10442721	Tucker et al.
FUNDED BY
APPLICANT(S)	Dennis S. Tucker (Huntsville, Alabama); Jeremy A. Tucker (Antioch, Tennessee)
ASSIGNEE(S)
INVENTOR(S)	Dennis S. Tucker (Huntsville, Alabama); Jeremy A. Tucker (Antioch, Tennessee)
ABSTRACT	In a unit gravity environment, a glass preform is encased in a material to generate an encased glass preform. The material remains solid at the glass preform's crystal melting temperature and is inert with respect to the glass preform. The encased glass preform is placed in a microgravity environment and heated to a temperature above the crystal melting temperature until the glass preform melts and is free of crystals, wherein a crystallite-free glass preform is encased within the material. The crystallite-free glass preform is then cooled in the microgravity environment to generate a solid crystallite-free glass preform encased within the material. While still in the microgravity environment, the material encasing the solid crystallite-free glass preform is removed in the microgravity environment and the solid crystallite-free glass preform is polished. A glass optical fiber is then drawn from the solid crystallite-free glass preform in the microgravity environment.
FILED	Monday, April 15, 2019
APPL NO	16/384118
ART UNIT	1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Manufacture, Shaping, or Supplementary Processes C03B 37/025 (20130101) C03B 37/01265 (20130101) Original (OR) Class C03B 2201/82 (20130101) C03B 2201/86 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 25/005 (20130101) C03C 25/106 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10444362 — LADAR data upsampling

US 10444362	Schaefer
FUNDED BY
APPLICANT(S)	RAYTHEON COMPANY (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Matthew A. Schaefer (Rowlett, Texas)
ABSTRACT	Systems and processes for increasing the effective sampling density of a LADAR data set are disclosed. LADAR data points are merged with data regarding edges of objects within the physical space represented by the LADAR data points to form a merged LADAR-edge point cloud. Each data point within the merged LADAR-edge point cloud is examined to identify co-planar neighboring data points within a defined search area. Additional data points are added to the LADAR-edge point cloud by interpolating between the identified, co-planar neighboring data points.
FILED	Tuesday, January 13, 2015
APPL NO	14/595631
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/89 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 7/30 (20170101) G06T 2207/10028 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, October 15, 2019.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20191015.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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