FedInvent™ Patents
Patent Details for Tuesday, October 22, 2019
This page was updated on Monday, March 27, 2023 at 05:55 AM GMT
Department of Health and Human Services (HHS)
| US 10448850 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Lihong Wang (St. Louis, Missouri); Yong Zhou (St. Louis, Missouri) |
| ABSTRACT | Methods for measuring blood flow speed within blood vessels using a PA imaging system are disclosed. The methods include position a field of view of a PA imaging system along a section of a blood vessel, introducing a PA discontinuity into the blood flow within the blood vessel upstream of the FOV of the PA system, monitoring the movement of the PA discontinuity during movement through the FOV of the PA imaging device, and calculate the blood flow speed using at least two measured positions and corresponding times of the PA discontinuity within the FOV of the PA imaging system. PA discontinuities may include blood surges formed by compressing and releasing the blood vessel and/or boluses of a fluid with high PA contrast relative to the blood, such as saline solution. |
| FILED | Monday, October 10, 2016 |
| APPL NO | 15/289319 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0095 (20130101) A61B 5/0275 (20130101) Original (OR) Class A61B 5/0295 (20130101) A61B 5/02233 (20130101) A61B 5/7278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10448852 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Peng-Sheng Chen (Indianapolis, Indiana); Shien-Fong Lin (Indianapolis, Indiana) |
| ABSTRACT | A system and method for monitoring nerve activity in a subject. The system includes a plurality of electrodes placed in proximity to skin of the subject, an amplifier electrically connected to the electrodes and configured to generate a plurality of amplified signals corresponding to electrical signals received from the subject through the electrodes, and a signal processor. The signal processor applies a high-pass filter to the amplified signals to generate filtered signals from the amplified signals, identifies autonomic nerve activity in the plurality of filtered signals; and generates an output signal corresponding to the filtered signals. The high-pass filter attenuates a plurality of the amplified signals having frequencies that correspond to heart muscle activity during a heartbeat. |
| FILED | Monday, December 09, 2013 |
| APPL NO | 14/649038 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/044 (20130101) A61B 5/046 (20130101) A61B 5/0245 (20130101) A61B 5/0402 (20130101) A61B 5/04001 (20130101) Original (OR) Class A61B 5/04018 (20130101) A61B 5/4035 (20130101) A61B 5/4836 (20130101) A61B 5/4848 (20130101) A61B 5/6869 (20130101) A61B 5/7203 (20130101) A61B 5/7425 (20130101) A61B 2562/0209 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3925 (20130101) A61N 1/36514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10448868 | Friedman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Nizan Friedman (Irvine, California); Justin Rowe (Irvine, California); David J. Reinkensmeyer (Irvine, California); Mark G. Bachman (Irvine, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Nizan Friedman (Irvine, California); Justin Rowe (Irvine, California); David J. Reinkensmeyer (Irvine, California); Mark G. Bachman (Irvine, California) |
| ABSTRACT | In one embodiment, a system includes apparatus for monitoring hand or wrist movement, the apparatus including a magnetic ring adapted to be worn on a finger of a patient and a data acquisition unit adapted to be worn on a wrist of the patient, the data acquisition unit including a magnetic sensor that can measure the strength and orientation of magnetic fields generated by the ring. |
| FILED | Monday, March 10, 2014 |
| APPL NO | 14/203455 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1118 (20130101) A61B 5/1122 (20130101) A61B 5/1126 (20130101) Original (OR) Class A61B 5/6825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10448877 | Truccolo et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wilson Truccolo (Providence, Rhode Island); Leigh R. Hochberg (Brookline, Massachusetts); John P. Donoghue (Providence, Rhode Island); Sydney S. Cash (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island); The General Hospital Corporation (Boston, Massachusetts); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Wilson Truccolo (Providence, Rhode Island); Leigh R. Hochberg (Brookline, Massachusetts); John P. Donoghue (Providence, Rhode Island); Sydney S. Cash (Cambridge, Massachusetts) |
| ABSTRACT | Several methods for prediction and detection of neurological events are proposed based on spatiotemporal patterns in recorded neural signals. The methods are illustrated with examples from neural data recorded from human and non-human primates. |
| FILED | Monday, December 05, 2011 |
| APPL NO | 13/991680 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/048 (20130101) A61B 5/0476 (20130101) A61B 5/0482 (20130101) A61B 5/04012 (20130101) A61B 5/4094 (20130101) Original (OR) Class A61B 5/7282 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10448883 | Grossman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); NuVu LLC (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); NuVu LLC (Cambridge, Massachusetts) |
| INVENTOR(S) | Nir Grossman (Loerrach, Germany); David Wang (Cambridge, Massachusetts); Edward Boyden (Chestnut Hill, Massachusetts) |
| ABSTRACT | A neuromodulator accurately measures—in real time and over a range of frequencies—the instantaneous phase and amplitude of a natural signal. For example, the natural signal may be an electrical signal produced by neural tissue, or a motion such as a muscle tremor. The neuromodulator generates signals that are precisely timed relative to the phase of the natural signal. For example, the neuromodulator may generate an exogenous signal that is phase-locked with the natural signal. Or, for example, the neuromodulator may generate an exogenous signal that comprises short bursts which occur only during a narrow phase range of each period of an oscillating natural signal. The neuromodulator corrects distortions due to Gibbs phenomenon. In some cases, the neuromodulator does so by applying a causal filter to a discrete Fourier transform in the frequency domain, prior to taking an inverse discrete Fourier transform. |
| FILED | Thursday, July 21, 2016 |
| APPL NO | 15/215597 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0476 (20130101) A61B 5/1101 (20130101) A61B 5/04001 (20130101) A61B 5/4836 (20130101) Original (OR) Class A61B 5/7253 (20130101) A61B 5/7257 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0622 (20130101) A61N 7/00 (20130101) A61N 2005/063 (20130101) A61N 2007/0021 (20130101) Electric Digital Data Processing G06F 17/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10448901 | McVeigh et al. |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Elliot Ross McVeigh (Timonium, Maryland); Amir Pourmorteza (Baltimore, Maryland) |
| ABSTRACT | An embodiment in accordance with the present invention provides a method and system for evaluating regional cardiac function and dyssynchrony from an imaging modality using the motion of endocardial features of the heart. In the method and system, an imaging modality such as a CT scanner is used to obtain an image sequence that is then processed using a computer program. The computer program is configured to create an endocardial mesh formed from triangular components that represents at least the region of interest of the subject's heart. From tracking the motion of conserved topological features on this endocardial mesh at least two time points a displacement map can be modeled. The displacement map can be further analyzed to determine metrics of regional cardiac function such as SQUEEZ, myocardial strain, torsion etc., and the displacement map can also be used to create visual representations of the function of the subject's heart. |
| FILED | Friday, October 12, 2012 |
| APPL NO | 14/350991 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/02 (20130101) A61B 5/0035 (20130101) A61B 5/0044 (20130101) A61B 5/055 (20130101) A61B 5/0073 (20130101) A61B 5/742 (20130101) A61B 5/1128 (20130101) A61B 5/02028 (20130101) A61B 5/4884 (20130101) A61B 5/7282 (20130101) Original (OR) Class A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/503 (20130101) A61B 6/5217 (20130101) A61B 6/5288 (20130101) A61B 2576/023 (20130101) Image Data Processing or Generation, in General G06T 7/246 (20170101) G06T 2207/10016 (20130101) G06T 2207/10081 (20130101) G06T 2207/30048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10448956 | Gordon et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF DEFENSE (Bethesda, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Chad Gordon (Lutherville, Maryland); Mehran Armand (Fulton, Maryland); Ryan Murphy (Columbia, Maryland); Gerald Grant (Goshen, Kentucky); Peter Liacouras (North Potomac, Maryland); Kevin Wolfe (Lutherville, Maryland); Ehsan Basafa (Baltimore, Maryland) |
| ABSTRACT | A method for computer-assisted planning of a transplant surgery is provided. The method includes obtaining a computer-readable representation of a donor and recipient skeletal fragment; determining surgical cutting planes on the computer-readable representation of the donor skeletal fragment from which a portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment will be harvested; determining virtual cutting guides; performing a virtual osteotomy to separate the portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment from a remainder portion of the donor skeletal fragment based on a position of the virtual cutting guides that are attached to the computer-readable representation of the donor skeletal fragment; positioning the donor skeletal fragment within a transplant region of the recipient skeletal fragment; and creating a hybrid computer-readable representation comprising the recipient skeletal fragment and the portion of the donor skeletal. |
| FILED | Wednesday, November 26, 2014 |
| APPL NO | 15/100215 |
| ART UNIT | 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/15 (20130101) Original (OR) Class A61B 17/176 (20130101) A61B 17/1695 (20130101) A61B 17/1739 (20130101) A61B 17/8085 (20130101) A61B 34/10 (20160201) A61B 34/20 (20160201) A61B 2034/105 (20160201) A61B 2034/108 (20160201) A61B 2034/2051 (20160201) A61B 2034/2055 (20160201) A61B 2034/2065 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2803 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) G06F 19/3481 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449084 | Chin et al. |
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| APPLICANT(S) | HydroGlyde Coatings LLC (Brookline, Massachusetts) |
| ASSIGNEE(S) | HydroGlyde Coatings LLC (Brookline, Massachusetts) |
| INVENTOR(S) | Stacy Lee Chin (Brookline, Massachusetts); Benjamin Goldman Cooper (Lynnfield, Massachusetts); Ruiqing Xiao (Boston, Massachusetts); Mark W. Grinstaff (Brookline, Massachusetts) |
| ABSTRACT | The invention provides a novel hydrophilic polymer and latex polymer blend coating formulation and compositions thereof, and their use on various devices (e.g., prophylactic and medical devices) to form hydrophilic and flexible coatings with durable lubricity. |
| FILED | Tuesday, February 05, 2019 |
| APPL NO | 16/267872 |
| ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 6/04 (20130101) Original (OR) Class Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/26 (20130101) B32B 27/28 (20130101) B32B 27/30 (20130101) B32B 27/36 (20130101) B32B 27/285 (20130101) B32B 27/302 (20130101) B32B 27/306 (20130101) B32B 2307/728 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/042 (20130101) C08J 2300/26 (20130101) C08J 2307/00 (20130101) C08J 2307/02 (20130101) C08J 2347/00 (20130101) C08J 2407/02 (20130101) C08J 2409/02 (20130101) Compositions of Macromolecular Compounds C08L 7/02 (20130101) C08L 9/08 (20130101) C08L 11/02 (20130101) C08L 29/04 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 107/02 (20130101) C09D 109/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449151 | Little et al. |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Steven R. Little (Allison Park, Pennsylvania); Siddharth Jhunjhunwala (Bengaluru, India) |
| ABSTRACT | The present invention contemplates induction of immunological tolerance thereby providing permanent allograft acceptance. This method obviates the need for a lifelong regimen of immunosuppressive agents which can increase the risk of infection, autoimmunity, and cancer. Immunological tolerance is thought to be mediated by regulatory T lymphocytes (Treg cells) with immunosuppressive capabilities. A therapeutically relevant platform comprising artificial constructs are contemplated comprising numerous soluble and surface bound Treg cell stimulating factors that may induce tolerance following allograft transplantation. Such artificial constructs, being the size of a cell, have surface bound monoclonal antibodies specific to regulatory T-cell surface moieties and encapsulated soluble regulatory T-cell modulating factors. |
| FILED | Thursday, August 10, 2017 |
| APPL NO | 15/674128 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1635 (20130101) Original (OR) Class A61K 9/1682 (20130101) A61K 38/1841 (20130101) A61K 38/1841 (20130101) A61K 38/2013 (20130101) A61K 38/2013 (20130101) A61K 47/6921 (20170801) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0065 (20130101) B01J 2208/00823 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449168 | Viola et al. |
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| APPLICANT(S) | The University of Toledo (Toledo, Ohio) |
| ASSIGNEE(S) | The University of Toledo (Toledo, Ohio) |
| INVENTOR(S) | Ronald E. Viola (Toledo, Ohio); Bharani Thangavelu (Toledo, Ohio); Vinay Mutthamsetty (Toledo, Ohio); Qinzhe Wang (Toledo, Ohio); Pravin Bhansali (Toledo, Ohio) |
| ABSTRACT | Phthalate derivatives that are aspartate-P-semialdehyde dehydrogenase (ASADH) inhibitor compounds, aspartate N-acetyltransferase (ANAT) inhibitor compounds, or both, are described, as well as methods of making the same, and methods of using the same. |
| FILED | Monday, August 29, 2016 |
| APPL NO | 15/755447 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 31/00 (20180101) Acyclic or Carbocyclic Compounds C07C 227/18 (20130101) C07C 229/38 (20130101) Technologies for Adaptation to Climate Change Y02A 50/475 (20180101) Y02A 50/481 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449174 | Kyei-Baffour et al. |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Kwaku Kyei-Baffour (West Lafayette, Indiana); Mohamed Seleem (West Lafayette, Indiana); Mingji Dai (West Lafayette, Indiana); Haroon Taj Mohammad (West Lafayette, Indiana) |
| ABSTRACT | Invasive fungal infections present a formidable global public health challenge due to the limited number of approved antifungal agents and the emergence of resistance to the frontline treatment options, such as fluconazole. Three fungal pathogens of significant concern are Candida, Cryptococcus, and Aspergillus given their propensity to cause opportunistic infections in immunocompromised individuals. This disclosure provides a set of aryl isonitrile compounds that possess broad-spectrum antifungal activity primarily against species of Candida and Cryptococcus. The most potent derivatives are capable of inhibiting growth of these key pathogens at concentrations as low as 0.5 μM. Remarkably, the most active compounds exhibit an excellent safety profile and are non-toxic to mammalian cells even at concentrations up to 256 μM. |
| FILED | Monday, March 13, 2017 |
| APPL NO | 15/456950 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/277 (20130101) Original (OR) Class A61K 31/4402 (20130101) A61K 31/4406 (20130101) A61K 31/4409 (20130101) Acyclic or Carbocyclic Compounds C07C 291/10 (20130101) C07C 2601/14 (20170501) Heterocyclic Compounds C07D 213/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449177 | John et al. |
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| APPLICANT(S) | Varghese John (San Francisco, California); Dale E. Bredesen (Novato, California) |
| ASSIGNEE(S) | Buck Institute for Research on Aging (Novato, California) |
| INVENTOR(S) | Varghese John (San Francisco, California); Dale E. Bredesen (Novato, California) |
| ABSTRACT | The invention provides compositions and methods for the treatment of mild cognitive impairment (MCI), and for inhibiting, reducing, delaying and/or preventing the progression of MCI to Alzheimer's disease. The methods entail administering an effective amount of one or more compounds selected from the group consisting of tropisetron, disulfuram, honokiol and nimetazepam. The methods also are useful for prophylactic and therapeutic treatment of amyloidogenic diseases, including Alzheimer's disease. |
| FILED | Friday, August 19, 2011 |
| APPL NO | 13/213960 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/145 (20130101) A61K 31/4035 (20130101) Original (OR) Class A61K 31/5513 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449182 | Weiss et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Robert H. Weiss (Vacaville, California); Bruce D. Hammock (Davis, California); Hiromi Inoue Wettersten (Sacramento, California); Sung Hee Hwang (Davis, California) |
| ABSTRACT | The present invention provides sorafenib analogs for use in a method of treating a disease mediated by p21, said method comprising administering to a subject in need thereof a therapeutically effective amount of a compound of formula I. The present invention also provides methods of inhibiting p21 in a cell comprising contacting the cell with an effective amount of a compound of formula I. |
| FILED | Thursday, June 20, 2013 |
| APPL NO | 14/408280 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/17 (20130101) A61K 31/44 (20130101) A61K 31/44 (20130101) A61K 31/196 (20130101) A61K 31/196 (20130101) A61K 31/277 (20130101) A61K 31/675 (20130101) A61K 31/675 (20130101) A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 31/4412 (20130101) Original (OR) Class A61K 31/4439 (20130101) A61K 33/24 (20130101) A61K 33/24 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449186 | Watt et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | David S. Watt (Lexington, Kentucky); Chunming Liu (Lexington, Kentucky); Vitaliy M. Sviripa (Lexington, Kentucky); Wen Zhang (Lexington, Kentucky); Markos Leggas (Lexington, Kentucky) |
| ABSTRACT | Halogenated phenylethynyl-substituted heterocycles that possess either an N-alkylamino or N,N-dialkylamino group attached to the heterocycle or halogenated phenylethynyl-substituted benzenes that a nitrogen-containing heterocycle attached to the benzene inhibit the proliferation cancer cells and are useful antineoplastic agents. |
| FILED | Thursday, May 10, 2018 |
| APPL NO | 15/976643 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/45 (20130101) Original (OR) Class A61K 31/47 (20130101) A61K 31/404 (20130101) A61K 31/416 (20130101) A61K 31/437 (20130101) A61K 31/472 (20130101) A61K 31/495 (20130101) A61K 31/4418 (20130101) A61K 31/4439 (20130101) A61K 31/4706 (20130101) A61K 31/4725 (20130101) A61K 31/4965 (20130101) A61K 31/5375 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449199 | Abazeed et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Mohamed Abazeed (Boston, Massachusetts); Matthew Meyerson (Boston, Massachusetts); Drew Adams (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for the use of radiation sensitizing agents in combination with radiation for the treatment of neoplasia, methods for the identification of genotype-specific radiation sensitizing agents, and methods of identifying patients who could benefit from therapy with a genotype-specific radiation sensitizing agent. |
| FILED | Monday, August 29, 2016 |
| APPL NO | 15/250402 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5377 (20130101) Original (OR) Class A61K 41/0038 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) A61N 2005/1098 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449200 | Yen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Institute for Cancer Research (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Research Institute of Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Timothy J. Yen (Haverford, Pennsylvania); Vikram Bhattacharjee (Philadelphia, Pennsylvania) |
| ABSTRACT | Methods for treating tumors comprise contacting tumor cells expressing the vitamin D receptor with a vitamin D receptor ligand that inhibits homologous recombination in the tumor cells, and contacting the tumor cells with an amount of a Poly(ADP) Ribose Polymerase 1 (PARP-1) inhibitor. Inhibiting homologous recombination produces a synergistic therapeutic effect between the vitamin D receptor ligand and PARP-1 inhibitor, and may overcome PARP-1 resistance in killing tumor cells. |
| FILED | Wednesday, December 20, 2017 |
| APPL NO | 15/848537 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) Original (OR) Class A61K 31/55 (20130101) A61K 31/593 (20130101) A61K 31/593 (20130101) A61K 31/7068 (20130101) A61K 31/7068 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449205 | Blau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Helen M. Blau (Stanford, California); Andrew Tri Van Ho (Stanford, California); Adelaida R. Palla (Stanford, California) |
| ABSTRACT | Provided herein are compositions, methods, and kits for proliferating muscle cells by exposing the muscle cells to a prostaglandin E2 (PGE2) compound or compound that activates PGE2 signaling. Also provided are methods for regenerating muscle in a subject suffering from muscular atrophy, dystrophy, and/or injury by administering a PGE2 compound alone or in combination with isolated muscle cells. The PGE2 compound in combination with the isolated muscle cells can be administered prophylactically to prevent a muscle disease or condition. |
| FILED | Wednesday, February 07, 2018 |
| APPL NO | 15/891278 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5575 (20130101) Original (OR) Class A61K 31/5575 (20130101) A61K 35/34 (20130101) A61K 35/34 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0658 (20130101) C12N 2501/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449207 | Hostetler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Karl Y. Hostetler (Del Mar, California); James R. Beadle (San Diego, California); Nadejda Valiaeva (San Diego, California) |
| ABSTRACT | The present disclosure relates, inter alia, to compositions and methods for treating viral diseases and cancer. There are disclosed lipophilic antiviral and anticancer acyclic nucleoside phosphonate diesters, preparation thereof, and methods of using the compounds to treat viral diseases and cancer. |
| FILED | Friday, August 24, 2018 |
| APPL NO | 16/111378 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0031 (20130101) A61K 9/0034 (20130101) A61K 31/675 (20130101) Original (OR) Class A61K 31/685 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) A61P 31/18 (20180101) A61P 31/20 (20180101) A61P 31/22 (20180101) A61P 35/02 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6512 (20130101) C07F 9/6561 (20130101) C07F 9/65583 (20130101) C07F 9/65616 (20130101) Technologies for Adaptation to Climate Change Y02A 50/467 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449221 | Kotton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts); BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts); BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Darrell Kotton (Newton, Massachusetts); Maria Serra (Turin, Italy); Anthony N. Hollenberg (Newton, Massachusetts); Anita A. Kurmann (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments herein relate in vitro methods of stem cell differentiation into thyroid hormone producing cells and tissues, and methods of use of these cells. |
| FILED | Friday, July 29, 2016 |
| APPL NO | 15/223603 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/55 (20130101) Original (OR) Class A61K 38/22 (20130101) A61K 38/24 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0617 (20130101) C12N 2500/30 (20130101) C12N 2500/42 (20130101) C12N 2501/11 (20130101) C12N 2501/115 (20130101) C12N 2501/117 (20130101) C12N 2501/155 (20130101) C12N 2501/375 (20130101) C12N 2501/415 (20130101) C12N 2513/00 (20130101) C12N 2533/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449229 | Cowman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York); London Health Sciences Centre Research Inc. (London, Canada) |
| ASSIGNEE(S) | New York University (New York, New York); London Health Sciences Centre Research Inc. (London, Canada) |
| INVENTOR(S) | Mary K. Cowman (Mohegan Lake, New York); Thorsten Kirsch (River Edge, New Jersey); Eric J. Strauss (New York, New York); Eva Ann Turley (London, Canada); Cornelia Toelg (Vienna, Canada); Leonard G. Luyt (London, Canada) |
| ABSTRACT | Provided are methods and compositions for cartilage repair. The method involves performing a surgical procedure at the site of a cartilage defect and administering a composition comprising a receptor for hyaluronan mediated motility (RHAMM)-mimetic peptide, and a high molecular weight hyaluronan. |
| FILED | Wednesday, August 19, 2015 |
| APPL NO | 15/504938 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/728 (20130101) A61K 31/728 (20130101) A61K 35/28 (20130101) A61K 38/10 (20130101) Original (OR) Class A61K 2300/00 (20130101) Peptides C07K 14/70585 (20130101) C07K 14/70596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449230 | Hamill et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kristina Hamill (La Jolla, California); Jeffrey D. Esko (San Diego, California); Lisa McCoy (La Jolla, California); Yitzhak Tor (San Diego, California) |
| ABSTRACT | Provided are transporters based on polymyxin B. Also provided are methods of using the transporters for intracellular delivery of cargo and methods of enhancing intracellular uptake of cargo. |
| FILED | Friday, October 06, 2017 |
| APPL NO | 15/727397 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/12 (20130101) Original (OR) Class A61K 47/62 (20170801) A61K 47/64 (20170801) A61K 47/6911 (20170801) A61K 47/6939 (20170801) Peptides C07K 7/62 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449231 | Stinchcomb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts); THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (Atlanta, Georgia) |
| ASSIGNEE(S) | TAKEDA VACCINES, INC. (Cambridge, Massachusetts); The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services (Atlanta, Georgia) |
| INVENTOR(S) | Dan T. Stinchcomb (Enumclaw, Washington); Claire Kinney (Fort Collins, Colorado); Richard M. Kinney (Fort Collins, Colorado); Jill A. Livengood (Fort Collins, Colorado) |
| ABSTRACT | Embodiments herein report compositions, uses and manufacturing of dengue virus constructs and live attenuated dengue viruses. Some embodiments concern a composition that includes, but is not limited to, a tetravalent dengue virus composition. In certain embodiments, compositions can include constructs of one or more serotypes of dengue virus, such as dengue-1 (DEN-1) virus, dengue-2 (DEN-2) virus, dengue-3 (DEN-3) or dengue-4 (DEN-4) virus constructs. In other embodiments, constructs disclosed herein can be combined in a composition to generate a vaccine against more one or more dengue virus constructs that may or may not be subsequently passaged in mammalian cells. |
| FILED | Thursday, April 20, 2017 |
| APPL NO | 15/492981 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7048 (20130101) A61K 38/162 (20130101) Original (OR) Class A61K 39/12 (20130101) A61K 2039/70 (20130101) A61K 2039/5254 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) C07K 14/1825 (20130101) C07K 19/00 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/09 (20130101) C12N 15/8613 (20130101) C12N 2770/24122 (20130101) C12N 2770/24134 (20130101) C12N 2770/24141 (20130101) C12N 2770/24143 (20130101) C12N 2770/24162 (20130101) Technologies for Adaptation to Climate Change Y02A 50/39 (20180101) Y02A 50/386 (20180101) Y02A 50/388 (20180101) Y02A 50/394 (20180101) Y02A 50/396 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449241 | Portnoy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Daniel A. Portnoy (Albany, California); Anat A. Herskovits (Morgan Hill, California); Gregory Crimmins (Berkeley, California) |
| ABSTRACT | Mutant Listeria bacteria that modulate interferon-β production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc. |
| FILED | Thursday, January 04, 2018 |
| APPL NO | 15/862439 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/02 (20130101) A61K 39/0208 (20130101) Original (OR) Class A61K 2039/52 (20130101) A61K 2039/58 (20130101) A61K 2039/522 (20130101) A61K 2039/585 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449242 | Hultgren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| INVENTOR(S) | Scott J. Hultgren (St. Louis, Missouri); Michael G. Caparon (St. Louis, Missouri); Jerome Pinkner (St. Louis, Missouri); Ana L. Flores-Mireles (St. Louis, Missouri) |
| ABSTRACT | The present invention relates to compositions comprising EbpA and methods of use thereof. Specifically, methods useful in the treatment and prevention of EbpA-associated infections. |
| FILED | Monday, November 13, 2017 |
| APPL NO | 15/811250 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/09 (20130101) Original (OR) Class A61K 2039/505 (20130101) A61K 2039/55566 (20130101) Peptides C07K 16/1267 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449259 | Law et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Shek Hang Benedict Law (New York, New York); Ching-Hsuan Tung (New York, New York); Vanessa Bellat (New York, New York) |
| ABSTRACT | The disclosure provides compositions comprising peptide-based nanofiber precursors and methods of using the same to inhibit cancerous cell growth and/or to deliver therapeutic or diagnostic agents to cells, e.g., cancerous cells. The compositions of the present technology include peptide-based nanofiber precursors as well as carrier complexes comprising a therapeutic or diagnostic agent, and a peptide-based nanofiber precursor. Also provided herein are methods for delivering a therapeutic or diagnostic agent to a cell comprising contacting the cell with a carrier complex including a therapeutic or diagnostic agent, and a peptide-based nanofiber precursor. |
| FILED | Friday, September 30, 2016 |
| APPL NO | 15/764188 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/70 (20130101) A61K 31/167 (20130101) A61K 31/704 (20130101) A61K 31/5365 (20130101) A61K 38/50 (20130101) A61K 38/063 (20130101) A61K 38/212 (20130101) A61K 38/2013 (20130101) A61K 38/2073 (20130101) A61K 47/42 (20130101) A61K 47/60 (20170801) A61K 47/65 (20170801) A61K 47/6953 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Enzymes C12Y 305/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449261 | Hallahan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| INVENTOR(S) | Dennis E. Hallahan (St. Louis, Missouri) |
| ABSTRACT | The present invention is directed towards the compositions of peptide constructs that bind to GRP78 and the methods of use thereof. |
| FILED | Friday, July 24, 2015 |
| APPL NO | 15/328829 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/60 (20170801) A61K 47/64 (20170801) A61K 51/065 (20130101) A61K 51/088 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2005/1098 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449269 | Fahmy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Tarek M. Fahmy (New Haven, Connecticut); Alan Dardik (Bethany, Connecticut) |
| ABSTRACT | Composite prosthetic patches with covalently bound particles for controlled drug release, and methods of making and using thereof, have been developed. The particles may encapsulate one or more therapeutic, prophylactic or diagnostic agent(s). Generally, the prosthetic patches are decellularized extracellular matrix such as bovine or porcine pericardium or synthetic polymeric materials. The size of the particles ranges from between 1 nm and 1000 μm, preferably from between 10 nm and 500 nm. In some embodiments, the agent is a therapeutic agent for treatment of neointimal hyperplasia. In other embodiments, the agent is a therapeutic agent for suppressing or resolving inflammation. In yet other embodiments, the agent is a therapeutic for mitigating scarring. |
| FILED | Monday, August 28, 2017 |
| APPL NO | 15/687738 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/4439 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/26 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 27/306 (20130101) A61L 27/3604 (20130101) A61L 27/3633 (20130101) A61L 27/3641 (20130101) Original (OR) Class A61L 27/3687 (20130101) A61L 2300/62 (20130101) A61L 2400/12 (20130101) A61L 2400/18 (20130101) A61L 2420/06 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449270 | Ju et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Young Min Ju (Winston-Salem, North Carolina); Francis Moussy (Uxbridge, United Kingdom); Thomas J. Koob (Santa Fe, New Mexico) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Young Min Ju (Winston-Salem, North Carolina); Francis Moussy (Uxbridge, United Kingdom); Thomas J. Koob (Santa Fe, New Mexico) |
| ABSTRACT | The subject invention concerns non-degradable three dimensional porous collagen scaffolds and coatings. These scaffolds can be prepared around sensors for implantation into a body. A specific embodiment of the invention concerns implantable glucose sensors. Sensors comprising a collagen scaffold of the invention have improved biocompatibility by minimizing tissue reactions while stimulating angiogenesis. The subject invention also concerns methods for preparing collagen scaffolds of the invention. The subject invention also concerns sensors that have a collagen scaffold of the invention around the exterior of the sensor. |
| FILED | Monday, February 27, 2017 |
| APPL NO | 15/443003 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1486 (20130101) A61B 5/14542 (20130101) A61B 5/14865 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/24 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/48 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 31/10 (20130101) A61L 31/10 (20130101) A61L 31/044 (20130101) A61L 31/129 (20130101) A61L 2400/02 (20130101) A61L 2400/18 (20130101) A61L 2420/02 (20130101) Compositions of Macromolecular Compounds C08L 89/06 (20130101) C08L 89/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449321 | Meyerhoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Mark E. Meyerhoff (Ann Arbor, Michigan); Nicolai Lehnert (Ann Arbor, Michigan); Yu Qin (Ann Arbor, Michigan); Andrew P. Hunt (Ann Arbor, Michigan); Elizabeth J. Brisbois (Ann Arbor, Michigan); Hang Ren (Salt Lake City, Utah) |
| ABSTRACT | A gas delivery device includes a nitric oxide generating system. The system has a medium including a source of nitrite ions. A working electrode is in contact with the medium. A Cu(II)-ligand complex is in contact with the working electrode. A reference/counter electrode is, or a reference electrode and a counter electrode are in contact with the medium and separated from the working electrode. An inlet conduit is to deliver nitrogen gas to the medium, and an outlet conduit is to transport a stream of nitrogen gas and nitric oxide from the medium. An inspiratory gas conduit is operatively connected to the outlet conduit to introduce an oxygen-containing gas and form an output gas stream of the gas delivery device. |
| FILED | Tuesday, April 11, 2017 |
| APPL NO | 15/484981 |
| ART UNIT | 3782 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/342 (20130101) A61M 1/1698 (20130101) A61M 1/3462 (20130101) A61M 16/12 (20130101) Original (OR) Class A61M 16/0875 (20130101) A61M 25/0043 (20130101) A61M 35/00 (20130101) A61M 2016/1025 (20130101) A61M 2016/1035 (20130101) A61M 2025/0057 (20130101) A61M 2202/0007 (20130101) A61M 2202/0007 (20130101) A61M 2202/0208 (20130101) A61M 2202/0208 (20130101) A61M 2202/0275 (20130101) A61M 2202/0275 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450263 | Pathak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southern Research Institute (Birmingham, Alabama) |
| ASSIGNEE(S) | Southern Research Institute (Birmingham, Alabama) |
| INVENTOR(S) | Ashish Kumar Pathak (Birmingham, Alabama); Syed Kaleem Ahmed (Hoover, Alabama); Corinne E. Augelli-Szafran (Homewood, Alabama); Joseph A. Maddry (Birmingham, Alabama) |
| ABSTRACT | The present disclosure is concerned with benzo annulene compounds that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, chikungunya, Venezuelan equine encephalitis, dengue, influenza, and zika, using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Thursday, February 08, 2018 |
| APPL NO | 15/892302 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) Acyclic or Carbocyclic Compounds C07C 233/29 (20130101) C07C 233/60 (20130101) C07C 233/65 (20130101) C07C 233/75 (20130101) Original (OR) Class C07C 235/48 (20130101) C07C 255/33 (20130101) C07C 255/41 (20130101) C07C 255/58 (20130101) C07C 311/21 (20130101) C07C 2601/02 (20170501) C07C 2601/04 (20170501) C07C 2602/12 (20170501) C07C 2603/74 (20170501) Heterocyclic Compounds C07D 209/46 (20130101) C07D 213/30 (20130101) C07D 213/56 (20130101) C07D 213/81 (20130101) C07D 223/16 (20130101) C07D 231/14 (20130101) C07D 233/90 (20130101) C07D 239/28 (20130101) C07D 241/24 (20130101) C07D 261/18 (20130101) C07D 271/12 (20130101) C07D 277/56 (20130101) C07D 307/68 (20130101) C07D 307/85 (20130101) C07D 309/08 (20130101) C07D 333/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450275 | Martin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Stephen F. Martin (Austin, Texas); James J. Sahn (Austin, Texas); Luisa Scott (Austin, Texas); Jonathan Thomas Pierce-Shimomura (Round Rock, Texas) |
| ABSTRACT | Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain. |
| FILED | Tuesday, December 22, 2015 |
| APPL NO | 14/978204 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) Heterocyclic Compounds C07D 221/24 (20130101) Original (OR) Class C07D 223/16 (20130101) C07D 401/06 (20130101) C07D 403/04 (20130101) C07D 403/06 (20130101) C07D 405/04 (20130101) C07D 405/06 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450277 | Evans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California); The University of Sydney (Sydney, Australia) |
| ASSIGNEE(S) | The Salk Institute for Biological Studies (La Jolla, California); University of Sydney (Sydney, Australia) |
| INVENTOR(S) | Ronald M. Evans (La Jolla, California); Michael Downes (San Diego, California); Annette Atkins (San Diego, California); Sungsoon Fang (La Jolla, California); Jae Myoung Suh (San Diego, California); Thomas J. Baiga (Escondido, California); Ruth T. Yu (La Jolla, California); John F. W. Keana (Eugene, Oregon); Christopher Liddle (Chertswood, Australia) |
| ABSTRACT | Novel compounds having a formula embodiments of a method of making the same, and of a composition comprising them are disclosed herein. Also disclosed are embodiments of a method of treating or preventing a metabolic disorder in a subject, comprising administering to a subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and treating or preventing a metabolic disorder in the subject. Additionally disclosed are embodiments of a method of treating or preventing inflammation in an intestinal region of a subject, comprising administering to the subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and thereby treating or preventing inflammation in the intestinal region of the subject. |
| FILED | Tuesday, November 27, 2018 |
| APPL NO | 16/200861 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) C07B 59/002 (20130101) C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 233/63 (20130101) C07C 2601/14 (20170501) C07C 2602/42 (20170501) Heterocyclic Compounds C07D 231/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450289 | Wipf et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Peter Wipf (Pittsburgh, Pennsylvania); Bennett Van Houten (Pittsburgh, Pennsylvania); Wei Qian (Pittsburgh, Pennsylvania); Chaemin Lim (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided herein are compounds having the general formula compositions, and methods useful for treating cancer and neurodegeneration. The compounds comprise a mitochondria-targeting moiety linked to β-lapachone or a β-lapachone derivative. |
| FILED | Wednesday, June 08, 2016 |
| APPL NO | 15/580416 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 311/92 (20130101) Original (OR) Class C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450292 | Ebright et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersesy (New Brunswick, New Jersey) |
| INVENTOR(S) | Richard H. Ebright (New Brunswick, New Jersey); Joel Freundlich (New Brunswick, New Jersey); Nisha Mittal (New Brunswick, New Jersey); Mark Jaskowski (New Brunswick, New Jersey); Juan Shen (New Brunswick, New Jersey) |
| ABSTRACT | The invention provides compounds that are inhibitors of bacterial RNA polymerase. The invention also provides compositions comprising such compounds, methods of making such compounds, and methods of using said compounds. The invention has applications in control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, and antibacterial therapy. |
| FILED | Friday, December 09, 2016 |
| APPL NO | 15/782002 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/381 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic or Carbocyclic Compounds C07C 49/83 (20130101) C07C 49/84 (20130101) C07C 49/753 (20130101) C07C 49/835 (20130101) C07C 2601/02 (20170501) C07C 2601/16 (20170501) Heterocyclic Compounds C07D 213/64 (20130101) C07D 213/643 (20130101) C07D 333/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450294 | Balbas et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Minna D. Balbas (San Francisco, California); Michael J. Evans (New York, New York); Charles L. Sawyers (New York, New York); Yang Shen (Chicago, Illinois); David Hosfield (Chicago, Illinois); Geoffrey L. Greene (Chicago, Illinois) |
| ABSTRACT | The present invention provides compounds useful as modulators, agonists or antagonists of androgen receptor (AR), compositions thereof, and methods of making and using the same. |
| FILED | Friday, May 12, 2017 |
| APPL NO | 15/594275 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Heterocyclic Compounds C07D 233/86 (20130101) C07D 235/02 (20130101) C07D 401/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450310 | Gray et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Jaebong Jang (Boston, Massachusetts); Dries De Clercq (Boston, Massachusetts); Michael Eck (Boston, Massachusetts); Pasi Janne (Nedham, Massachusetts) |
| ABSTRACT | The present application provides bifunctional compounds of Formula (I): which act as protein degradation inducing moieties for EGFR and/or a mutant thereof. The present application also describes methods for the targeted degradation of EGFR and/or a mutant thereof through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to EGFR and/or a mutant thereof which can be utilized in the treatment of disorders modulated by EGFR or a mutant thereof. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/163254 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/18 (20130101) A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 417/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450355 | Markovitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | David M. Markovitz (Ann Arbor, Michigan); Jeanne A. Stuckey (Fenton, Michigan); Daniel M. Boudreaux (Frederick, Maryland); Jennifer Meagher (Plymouth, Michigan); Hashim Al-Hashimi (Chapel Hill, North Carolina); Loic Salmon (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein are chemical compounds, methods for their discovery, and their therapeutic and research use. Further provided herein are antiviral and antimicrobial lectin compounds and methods of their use. |
| FILED | Wednesday, September 16, 2015 |
| APPL NO | 15/511554 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0034 (20130101) A61K 38/00 (20130101) A61K 38/168 (20130101) A61K 38/1732 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/16 (20130101) A61L 31/047 (20130101) A61L 2300/404 (20130101) A61L 2300/408 (20130101) Peptides C07K 14/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450359 | Wong et al. |
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| FUNDED BY |
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| APPLICANT(S) | Altor Bioscience Corporation (Miramar, Florida) |
| ASSIGNEE(S) | Altor Bioscience Corporation (Miramar, Florida) |
| INVENTOR(S) | Hing C. Wong (Weston, Florida); Peter Rhode (Miami, Florida); Xiaoyun Zhu (Miami, Florida); Kai-ping Han (Miramar, Florida) |
| ABSTRACT | The instant invention provides soluble fusion protein complexes and IL-15 variants that have therapeutic and diagnostic use, and methods for making the such proteins. The instant invention additionally provides methods of stimulating or suppressing immune responses in a mammal using the fusion protein complexes and IL-15 variants of the invention. |
| FILED | Thursday, September 01, 2016 |
| APPL NO | 15/254713 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1774 (20130101) A61K 38/1793 (20130101) A61K 38/2086 (20130101) Peptides C07K 14/5443 (20130101) Original (OR) Class C07K 14/7051 (20130101) C07K 14/7155 (20130101) C07K 16/18 (20130101) C07K 16/28 (20130101) C07K 2319/00 (20130101) C07K 2319/31 (20130101) C07K 2319/33 (20130101) C07K 2319/74 (20130101) C07K 2319/75 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/09 (20130101) C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450368 | Haynes et al. |
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| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Barton F. Haynes (Durham, North Carolina); Hua-Xin Liao (Durham, North Carolina); Mattia Bonsignori (Durham, North Carolina) |
| ABSTRACT | The invention relates to the identification of monoclonal HIV-1 neutralizing antibodies, such as, but not limited to, antibodies that bind to the CD4 binding site (CD4bs) of HIV-1 gp120, their recombinant expression and purification and uses. In certain aspects, the invention provides a pharmaceutical composition comprising anyone of the antibodies of the invention or fragments thereof or any combination thereof. In certain aspects the invention provides methods to treat or prevent HIV-1 infection in a subject comprising administering to the subject a pharmaceutical composition comprising any one of the inventive antibodies or fragments thereof. |
| FILED | Monday, March 21, 2016 |
| APPL NO | 15/559171 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/507 (20130101) Peptides C07K 16/1045 (20130101) C07K 16/1063 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/34 (20130101) C07K 2317/52 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450371 | Clauss et al. |
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| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Matthias Clauss (Indianapolis, Indiana); Irina Petrache (Indianapolis, Indiana); Robert Voswinckel (Geissen, Germany) |
| ABSTRACT | The present invention provides methods for diagnosing a patient with emphysema, COPD of lung injury caused by tobacco use by detecting the levels of EMAP II in a sample. Disclosed herein are the hypervariable regions for a rat monoclonal antibody that binds to a form of EMAP II. This disclosure also includes a polypeptide sequence included in EMAP II that is the target for the binding of the antibody to its target protein. This epitope serves as the basis for a humanized antibody that can be used to treat patients that suffer from pathologies that exhibit elevated levels of EMAP II expression. |
| FILED | Wednesday, October 18, 2017 |
| APPL NO | 15/787237 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) C07K 16/22 (20130101) Original (OR) Class C07K 16/2866 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450372 | Hanada et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Kenichi Hanada (Bethesda, Maryland); Qiong J. Wang (Potomac, Maryland); James C. Yang (Bethesda, Maryland); Zhiya Yu (Potomac, Maryland) |
| ABSTRACT | Disclosed is a synthetic T cell receptor (TCR) having antigenic specificity for an HLA-A2-restricted epitope of thyroglobulin (TG), TG470-478. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, and populations of cells are also provided. Antibodies, or an antigen binding portion thereof, and pharmaceutical compositions relating to the TCRs of the disclosure are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Thursday, November 12, 2015 |
| APPL NO | 15/524869 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Peptides C07K 14/7051 (20130101) C07K 16/26 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2317/565 (20130101) C07K 2318/20 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450375 | Frenette et al. |
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| FUNDED BY |
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| APPLICANT(S) | Paul S. Frenette (New York, New York); Barry S. Coller (New York, New York); Aslihan Turhan (New York, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Paul S. Frenette (New York, New York); Barry S. Coller (New York, New York); Aslihan Turhan (New York, New York) |
| ABSTRACT | The present invention relates to methods of treating sickle cell disease comprising reducing, in a subject in need of such treatment, the adherence between sickle RBCs and leukocytes. It is based, at least in part, on the discovery that leukocytes play a direct role in the initiation of venular occlusion. The present invention further provides for methods for identifying agents which decrease SS-RBC/leukocyte adherence and for animal models which may be used to further elucidate the mechanism of vaso-occlusion in sickle cell crises. |
| FILED | Wednesday, November 03, 2004 |
| APPL NO | 10/980496 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/241 (20130101) C07K 16/2839 (20130101) Original (OR) Class C07K 16/2851 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450383 | Marasco et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Wayne A. Marasco (Wellesley, Massachusetts); Agnes Lo (Jamaica Plain, Massachusetts); Chen Xu (Beijing, China PRC); Quan Zhu (Southborough, Massachusetts) |
| ABSTRACT | The invention provides scFv antibodies and monoclonal antibodies that bind to and decrease an activity of Carbonic Anhydrase IX (G250). Also provided are the methods of treating and/or preventing cancer, such as renal clear cell cancer. Also provided are methods of identifying a carbonic anhydrase IX (G250) protein. The invention additionally provides methods of modifying immune effector cells, and the immune effector cells modified thereby. |
| FILED | Tuesday, May 09, 2017 |
| APPL NO | 15/590678 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/2013 (20130101) A61K 39/3955 (20130101) A61K 51/1045 (20130101) A61K 51/1075 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/30 (20130101) C07K 16/40 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450384 | Dinarello et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado); Konkuk University Industry Cooperation Foundation (Chungcheongbuk-do, South Korea) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado); Konkuk University Industry Cooperation Foundation (Chungju, South Korea) |
| INVENTOR(S) | Charles A. Dinarello (Denver, Colorado); Soohyun Kim (Greenwood Village, Colorado) |
| ABSTRACT | Embodiments herein report compositions of alpha-1 antitrypsin fusion polypeptides or peptide derivatives thereof. In certain embodiments, compositions and methods relate to generating a construct of use in pharmaceutically acceptable compositions to treat a subject in need of alpha-1 antitrypsin therapy or treatment. In other embodiments, compositions and methods disclosed herein concern linking alpha-1 antitrypsin or derivative thereof to an immune fragment. |
| FILED | Wednesday, March 14, 2018 |
| APPL NO | 15/921469 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/57 (20130101) Peptides C07K 14/8125 (20130101) C07K 16/40 (20130101) Original (OR) Class C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450566 | Cubillos-Ruiz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Juan R. Cubillos-Ruiz (New York, New York); Laurie H. Glimcher (Boston, Massachusetts) |
| ABSTRACT | Described herein is a previously unknown function of XBP1 in controlling anti-tumor immunity. It is shown that inhibiting XBP1 in tumor-associated dendritic cells inhibits tumor growth and induces protective anti-tumor immune responses. |
| FILED | Wednesday, March 14, 2018 |
| APPL NO | 15/921322 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/1137 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2320/31 (20130101) Enzymes C12Y 207/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450569 | Dallas et al. |
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| FUNDED BY |
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| APPLICANT(S) | SOMAGENICS, INC. (Santa Cruz, California) |
| ASSIGNEE(S) | SOMAGENICS, INC. (Santa Cruz, California) |
| INVENTOR(S) | Anne Dallas (Santa Cruz, California); Heini Ilves (Santa Cruz, California); Sumedha Jayasena (Santa Cruz, California); Brian H. Johnston (Santa Cruz, California) |
| ABSTRACT | Wound healing is a complex homeostatic process in which several distinct types coordinate to repair a physical damage. Failure to close wounds contributes to the pathology of conditions like diabetes mellitus, particularly in the elderly. Presented herein are molecules, pharmaceutical compositions, and methods for applying small RNA oligonucleotide technology to wound healing. Small RNA oligonucleotide approaches as disclosed herein provide a therapeutic strategy for improving both basal and pathological wound healing. |
| FILED | Friday, August 12, 2016 |
| APPL NO | 15/752182 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1131 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/317 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/531 (20130101) C12N 2310/3231 (20130101) C12N 2310/3521 (20130101) C12N 2310/3533 (20130101) Enzymes C12Y 114/11002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450570 | Simons et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Michael Simons (Hamden, Connecticut); Pengchun Yu (New Haven, Connecticut) |
| ABSTRACT | The invention relates to compositions and methods for reducing excessive vascular development and treat related disorders. In one aspect, the invention provides methods for treating, reducing or inhibiting vascular development in a subject in need thereof. The methods of the invention comprises administering to the subject an effective amount of a HK2 depleting agent that decreases the level of expression and/or activity of HK2. In some embodiments, the level of expression and/or activity of fibroblast growth factor receptor (FGFR), FGF ligand and/or FGF signaling is/are decreased. The invention also includes methods for diagnosing excessive vascular development and for measuring the efficacy of a treatment for an excessive vascular development in a subject in need thereof. The invention further includes a pharmaceutical composition for treating or reducing angiogenesis or lymphangiogenesis, comprising a HK2 depleting agent and a pharmaceutical acceptable carrier. |
| FILED | Monday, December 04, 2017 |
| APPL NO | 15/830420 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 15/1138 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2333/912 (20130101) G01N 2800/32 (20130101) G01N 2800/52 (20130101) G01N 2800/7014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450572 | Van Etten et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jamie Lynn Van Etten (Minneapolis, Minnesota); Scott M. Dehm (Rochester, Minnesota) |
| ABSTRACT | This document relates to materials and methods for treating cancer (e.g., prostate cancer). For example, methods for using one or more androgen receptor variant (AR-V) inhibitors (e.g., morpholinos) to treat a mammal having prostate cancer (e.g., castration-resistant prostate cancer) are provided. |
| FILED | Friday, August 11, 2017 |
| APPL NO | 15/675072 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/314 (20130101) C12N 2310/3233 (20130101) C12N 2310/3513 (20130101) C12N 2320/31 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450573 | Chang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Andrew L. Chang (Redwood City, California); Christina D. Smolke (Menlo Park, California) |
| ABSTRACT | Aptamers that specifically bind to ligands of folinic acid, a folate, and derivatives thereof (which may be referred to herein as ligands) are provided, and compositions and methods of use thereof. The aptamers and switches of the invention provide biological sensing capability for detecting the ligands, and are effective in sensing in vitro and in vivo. By specific sensing of the ligand, the aptamers of the invention provide a means of engineering an inducible gene regulatory system that enables dose-dependent control over gene expression in response to the ligand, in vivo and in vitro. |
| FILED | Thursday, August 13, 2015 |
| APPL NO | 15/502694 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/12 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) C12N 2310/121 (20130101) C12N 2310/122 (20130101) C12N 2310/141 (20130101) C12N 2310/351 (20130101) C12N 2310/3519 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450596 | Intlekofer et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Andrew M. Intlekofer (New York, New York); Craig B. Thompson (New York, New York) |
| ABSTRACT | The present disclosure provides, among other things, methods and compositions for diagnosing and treating stress-induced injuries, hypoxia in particular. The present invention is based, in part, on the novel discovery that a metabolite, L-2-hydroxyglutarate, and certain enzymes and substrates regulating its metabolism, mediate stress-induced cellular mechanisms. In some embodiments, provided methods and compositions are used to diagnose and treat diseases with hypoxia-induced injuries. In some embodiments, provided methods and compositions are used to modulate cell pluripotency or differentiation in vivo or in vitro. |
| FILED | Friday, March 27, 2015 |
| APPL NO | 15/129167 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/711 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/32 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) G01N 2500/10 (20130101) G01N 2800/7038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450599 | Pierce et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Niles A. Pierce (Pasadena, California); Harry Ming Tak Choi (Pasadena, California) |
| ABSTRACT | The present disclosure relates to methods and compositions involving HCR reactions that involve initiators that are split into two or more parts. Effective HCR is dependent upon two or more of these split initiators being brought into proximity (e.g., via binding events mediated by a target) such that a full initiator is formed that is capable of triggering HCR signal amplification. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/639100 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450602 | Cawthon |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Richard M. Cawthon (Salt Lake City, Utah) |
| ABSTRACT | Disclosed herein are methods and compositions for determining the copy number of a first target nucleic acid as compared to the copy number of a second target nucleic acid in a single well with a single detection label. For example, disclosed herein are methods and compositions for determining the copy number of a first target nucleic acid as compared to the copy number of a second target nucleic acid by a monochrome multiplex quantitative PCR (MMQPCR) in a single well with a single detection label. |
| FILED | Friday, June 23, 2017 |
| APPL NO | 15/631694 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 1/6851 (20130101) Original (OR) Class C12Q 1/6851 (20130101) C12Q 2525/155 (20130101) C12Q 2527/107 (20130101) C12Q 2537/143 (20130101) C12Q 2545/101 (20130101) C12Q 2563/173 (20130101) C12Q 2563/173 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450609 | Sukumar et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Saraswati Sukumar (Columbia, Maryland); Mary Jo Fackler (Hunt Valley, Maryland); Wei Wen Teo (Johor Bahru Johor, Malaysia); Zoila Areli Lopez Bujanda (Bethesda, Maryland); Antonio Wolff (Baltimore, Maryland) |
| ABSTRACT | The cMethDNA method of the present invention is a novel modification of the QM-MSP method (U.S. Pat. No. 8,062,849), specifically intended to quantitatively detect tumor DNA (or other circulating DNAs) in fluids such as serum or plasma at the lowest copy number yet reported. Unique compared to any other PCR-based assay, a small number of copies of a synthetic polynucleotide standard (STDgene) is added to an aliquot of patient serum with standards for a plurality of genes of interest (TARGETgene). Once total DNA is purified PCR is performed wherein the STDgene and the TARGETgene are co-amplified with the same external primer set, and the amplicons present in a dilution of the first PCR reaction are subjected to real time PCR, and quantified for each gene. Methods of making the STDgene standards and the use of the cMethDNA methods and kits containing the same are disclosed. |
| FILED | Wednesday, May 22, 2013 |
| APPL NO | 14/402434 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2523/125 (20130101) C12Q 2525/301 (20130101) C12Q 2545/114 (20130101) C12Q 2563/107 (20130101) C12Q 2565/1015 (20130101) C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450615 | Markowitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Sanford D. Markowitz (Pepper Pike, Ohio); Joseph Willis (Shaker Heights, Ohio); Amitabh Chak (University Heights, Ohio); Rom Leidner (Portland, Oregon) |
| ABSTRACT | This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/388029 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/136 (20130101) C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450620 | de Vlaminick et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Iwijn de Vlaminick (Stanford, California); Michael Kertesz (Menlo Park, California); Kiran Kaur Khush (Stanford, California); Mark Alec Kowarsky (Victoria, Australia); Lance Martin (Half Moon Bay, California); Stephen R. Quake (Stanford, California); Hannah Valantine (Stanford, California) |
| ABSTRACT | Methods, devices, compositions and kits are provided for analysis of the microbiome or individual components thereof in an individual. The methods find use in a determination of infection, in analysis of the microbiome structure, in determining the immunocompetence of an individual, and the like. In some embodiments of the invention, the individual is treated with a therapeutic regimen, e.g. drugs, diet, radiation therapy, and the like. |
| FILED | Friday, November 07, 2014 |
| APPL NO | 14/536300 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/701 (20130101) C12Q 1/705 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 1/6895 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 30/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450641 | Matras et al. |
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| FUNDED BY |
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| APPLICANT(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Maxime R. Matras (Tallahassee, Florida); Eric Hellstrom (Tallahassee, Florida); Ulf Trociewitz (Crawfordsville, Florida); Jianyi Jiang (Tallahassee, Florida); David Larbalestier (Tallahassee, Florida) |
| ABSTRACT | Methods of pre-densifying a metal wire containing superconductor materials are provided. Superconductor materials containing the pre-densified wires also are provided. The wires may be pre-densified by subjecting a metal wire that includes one or more filament cavities in which a superconductor precursor powder is disposed to a temperature and a first pressure for a time sufficient to densify the superconductor precursor powder to form a pre-densified metal wire, wherein the temperature is less than the melting point of the superconductor precursor powder, and the first pressure is sufficient, at the temperature, to compress at least a portion of the metal wire. |
| FILED | Wednesday, July 27, 2016 |
| APPL NO | 15/221042 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451188 | Harbrecht et al. |
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| FUNDED BY |
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| APPLICANT(S) | Semba Biosciences, Inc. (Madison, Wisconsin) |
| ASSIGNEE(S) | Semba Biosciences, Inc. (Madison, Wisconsin) |
| INVENTOR(S) | Brian A. Harbrecht (Janesville, Wisconsin); Robert Charles Mierendorf (Verona, Wisconsin); Scott G. Manke (Sun Prairie, Wisconsin) |
| ABSTRACT | An illustrative valve block includes a pressure plate, a fluid transfer block, and a diaphragm. The pressure plate includes a pressure channel configured to receive a pressurized first fluid and a recess in a surface of the pressure plate. The pressure channel and the recess are fluidly connected. The fluid transfer block includes an inlet connection configured to receive a second fluid and an outlet connection. The fluid transfer block also includes a plurality of valve inlet bores each fluidly connected to the inlet connection. The plurality of valve inlet bores are distributed along at least part of a first circular shape. The fluid transfer block further includes a plurality of valve outlet bores each fluidly connected to the outlet connection. |
| FILED | Tuesday, December 01, 2015 |
| APPL NO | 15/534369 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Separation B01D 15/22 (20130101) B01D 15/1842 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 7/17 (20130101) Original (OR) Class F16K 11/22 (20130101) F16K 25/005 (20130101) F16K 27/003 (20130101) F16K 27/0236 (20130101) F16K 27/0263 (20130101) F16K 31/1266 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451402 | Yaqoob et al. |
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| FUNDED BY |
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| APPLICANT(S) | Zahid Yaqoob (Cambridge, Massachusetts); Wonshik Choi (Seoul, North Korea); Toyohiko Yamauchi (Hamamatsu, Japan); Michael Feld (, None); David Feld (Newark, California); Alison Hearn (Jamaica Plain, Massachusetts); Jonathan Feld (Somerville, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Hamamatsu Photonics K.K. (Hamamatsu, Japan) |
| INVENTOR(S) | Zahid Yaqoob (Cambridge, Massachusetts); Wonshik Choi (Seoul, North Korea); Toyohiko Yamauchi (Hamamatsu, Japan); Michael Feld (, None) |
| ABSTRACT | The present invention relates to a full-field reflection phase microscope. In a preferred embodiment, the invention can combine low-coherence interferometry and off-axis digital holographic microscopy (DHM). The reflection-based DHM provides highly sensitive and a single-shot imaging of cellular dynamics while the use of low coherence source provides a depth-selective measurement. A preferred embodiment of the system uses a diffraction grating in the reference arm to generate an interference image of uniform contrast over the entire field-of-view albeit low-coherence light source. With improved path-length sensitivity, the present invention is suitable for full-field measurement of membrane dynamics in live cells with sub-nanometer-scale sensitivity. |
| FILED | Wednesday, January 25, 2012 |
| APPL NO | 13/358254 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/04 (20130101) Original (OR) Class G01B 9/0207 (20130101) G01B 9/02032 (20130101) G01B 9/02047 (20130101) G01B 9/02064 (20130101) G01B 9/02084 (20130101) G01B 9/02091 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/45 (20130101) Optical Elements, Systems, or Apparatus G02B 27/50 (20130101) G02B 27/1086 (20130101) Holographic Processes or Apparatus G03H 1/0443 (20130101) G03H 2001/005 (20130101) G03H 2001/0456 (20130101) G03H 2001/0467 (20130101) G03H 2222/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451587 | Rosenzweig et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Stephen J. Rosenzweig (Seattle, Washington); Ned C. Rouze (Durham, North Carolina); Brett C. Byram (Brentwood, Tennessee); Mark L. Palmeri (Durham, North Carolina); Kathryn R. Nightingale (Durham, North Carolina) |
| ABSTRACT | Methods, systems and computer program products for determining a mechanical parameter for a sample having a target region, include determining a prior probability density function that characterizes at least one physical property of the target region; generating a displacement of the sample in the target region to form a shear wave that propagates orthogonal to a direction of the displacement; transmitting tracking pulses in the target region; receiving corresponding echo signals for the tracking pulses in the target region at a plurality of lateral positions; estimating a propagation parameter of the shear wave in response to the echo signals and the prior probability density function using statistical inference; and determining at least one mechanical parameter of the target region based on the estimated propagation parameter. |
| FILED | Thursday, July 16, 2015 |
| APPL NO | 14/801007 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) Original (OR) Class G01N 29/449 (20130101) G01N 29/4472 (20130101) G01N 2291/0422 (20130101) G01N 2291/02827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451608 | Deisseroth et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Karl Deisseroth (Stanford, California); Feng Zhang (Cambridge, Massachusetts); Viviana Gradinaru (Menlo Park, California); M. Bret Schneider (Portola Valley, California) |
| ABSTRACT | A variety of applications, systems, methods and constructs are implemented for use in connection with screening of ion-channel modulators. Consistent with one such system, drug candidates are screened to identify their effects on cell membrane ion channels and pumps. The system includes screening cells having light responsive membrane ion switches, voltage-gated ion switches and fluorescence producing voltage sensors. A chemical delivery device introduces the drug candidates to be screened. An optical delivery device activates the light responsive ion switches. An optical sensor monitors fluorescence produced by the voltage sensors. A processor processes data received from the optical sensor. A memory stores the data received from the optical sensor. |
| FILED | Thursday, May 12, 2016 |
| APPL NO | 15/153305 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0622 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00315 (20130101) B01J 2219/00495 (20130101) B01J 2219/00702 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 60/12 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) Original (OR) Class G01N 33/5008 (20130101) G01N 33/6872 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451611 | Akassoglou et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE J. DAVID GLADSTONE INSTITUTES (San Francisco, California) |
| ASSIGNEE(S) | THE J. DAVID GLADSTONE INSTITUTE (Redwood City, California) |
| INVENTOR(S) | Katerina Akassoglou (San Francisco, California); Jae Kyu Ryu (San Francisco, California); Anke Meyer-Franke (Menlo Park, California) |
| ABSTRACT | The present invention provides compositions exhibiting in vivo activity of fibrin in an in vitro setting, in vitro assays comprising such compositions, methods of producing such compositions, and methods of using such compositions and assays. The compositions of the invention include molecules with the biochemical properties of 1) high affinity binding to fibrin receptors and 2) activation of cell-signaling systems comparable to that observed in vivo by fibrin. The fibrin compositions of the invention are compatible both in biochemical assays and cell-based assays, and thus useful for in vitro assays for screening of test agents that modulate cell activation and/or signaling pathways mediated by fibrin or associated with fibrin activity. |
| FILED | Friday, January 09, 2015 |
| APPL NO | 15/109160 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5055 (20130101) G01N 33/5058 (20130101) Original (OR) Class G01N 2333/75 (20130101) G01N 2333/70553 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451628 | Mulvihill et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Sean J. Mulvihill (Salt Lake City, Utah); Matthew A. Firpo (Salt Lake City, Utah) |
| ABSTRACT | The present invention provides biomarker compositions and methods for the diagnosis and prognosis of PDAC. In a particular embodiment, the invention provides methods and compositions for screening, diagnosis and prognosis of early stage, asymptomatic PDAC. |
| FILED | Wednesday, May 06, 2015 |
| APPL NO | 15/308579 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57438 (20130101) Original (OR) Class G01N 33/57488 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) G01N 2800/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451632 | Bertozzi et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Carolyn R. Bertozzi (Stanford, California); Christina Woo (Berkeley, California) |
| ABSTRACT | Methods for producing isotopically-labelled peptides are provided. Aspects of the method include: contacting a sample including a metabolically tagged protein with a cleavable probe to produce a probe-protein conjugate; separating the probe-protein conjugate from the sample; digesting the probe-protein conjugate to produce a probe-peptide conjugate; and cleaving a cleavable linker to release an isotopically labelled peptide. The method may further include: identifying a predetermined isotopic pattern in a mass spectrum; determining an amino acid sequence of the isotopically labelled peptide; and identifying the site of protein glycosylation based on the determined amino acid sequence. Also provided are cleavable probes for practicing the subject methods, described by the Formula: A-L-(M-Z) where A is an affinity tag, L is a cleavable linker, M is an isotopic label and Z is a chemoselective tag capable of cross-linking a metabolically tagged protein. Compositions and kits for practicing the subject methods are also provided. |
| FILED | Monday, October 22, 2018 |
| APPL NO | 16/167181 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/00 (20130101) C07F 7/1804 (20130101) Peptides C07K 1/13 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) Original (OR) Class G01N 2440/38 (20130101) G01N 2458/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451641 | Shah |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Svati Shah (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are compositions and methods for targeted metabolomics profiling to provide absolute quantification of a broad array of metabolic intermediates of fatty acids, amino acids, and carbohydrate metabolism for HFpEF. In an aspect, the disclosure relates to a method for assessing risk of death or a major adverse cardiac event (MACE) in a subject diagnosed with heart failure with preserved ejection fraction (HFpEF). The method may include (a) determining in a sample from the subject the level of each metabolite in at least one factor, wherein the factor is selected from the group consisting of factor 1, factor 3, factor 4, factor 5, factor 10, factor 12, and factor 14; and (b) comparing the level of each metabolite in the sample to a standard, wherein the level of the metabolite in the subject relative to a standard is indicative of the risk of death or MACE in the subject. |
| FILED | Monday, March 14, 2016 |
| APPL NO | 15/557621 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/1468 (20130101) A61B 5/4842 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) G01N 33/64 (20130101) G01N 33/92 (20130101) Original (OR) Class G01N 33/6812 (20130101) G01N 33/6893 (20130101) G01N 2560/00 (20130101) G01N 2570/00 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) G01N 2800/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451700 | Weingartner et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Sebastian Weingartner (Heidelberg, Germany); Mehmet Akcakaya (Minneapolis, Minnesota) |
| ABSTRACT | A system and method for obtaining magnetic resonance images are provided. The system is programmed to control the RF system to apply a saturation pulse at a reference frequency that saturates a selected labile spin species of the subject. The system is programmed to control the RF system to apply an inversion pulse after a variable delay. The system is programmed to control the RF system and the plurality of gradient coils to apply a motion sensitized driven equilibrium (MSDE) preparation pulse. The system is programmed to control the plurality of gradient coils to read imaging data during an acquisition time period. The system is programmed to reconstruct a T1 mapping image of the subject with black-blood contrast. |
| FILED | Tuesday, September 05, 2017 |
| APPL NO | 15/695259 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5602 (20130101) G01R 33/5607 (20130101) G01R 33/5614 (20130101) G01R 33/56545 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10452746 | Herzenberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Leonore A. Herzenberg (Stanford, California); Guenther Walther (Stanford, California); Wayne A. Moore (San Francisco, California); Noah Zimmerman (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of The Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Leonore A. Herzenberg (Stanford, California); Guenther Walther (Stanford, California); Wayne A. Moore (San Francisco, California); Noah Zimmerman (Palo Alto, California) |
| ABSTRACT | A method and apparatus for quantitatively measuring differences between portions of a multivariate, multi-dimensional sample distribution, may comprise summarizing the data by dividing the data into clusters each having a signature representative of a position of the cluster and a fraction of the entire distribution within the cluster; matching a plurality of first supplier signatures to a respective one of a plurality of second receiver signatures using a cost factor indicative of the separation between first signature elements and second signature elements; and determining a measurement of the work required to transform the first signature to the second signature. The step of determining a measurement of the work may comprise applying the earth mover distance (“EMD”) algorithm between the first signature or elements of the first signature and the respective second signatures or elements of the respective second signature. |
| FILED | Tuesday, January 03, 2012 |
| APPL NO | 13/342722 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10452876 | Ganesan et al. |
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| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Deepak Ganesan (Amherst, Massachusetts); Pan Hu (Palo Alto, California); Pengyu Zhang (Palo Alto, California) |
| ABSTRACT | Systems and methods for backscatter communications are provided that employ a backscatter reader to transmit a carrier signal to multiple backscatter tags having heterogeneous hardware and specifications. In response to receiving the carrier, the tags encode data into the received signal and, concurrently, transmit their respective backscattered signal to the reader. The concurrent signals are received by the reader as a combined signal. The reader detects edges in the received signal, based on the corresponding in-phase (I) and quadrature (Q) signals. The edges are then assigned to streams based on the offset or transmission rate of the tags. In some cases, the reader can detect edge collisions. These collisions can be resolved by causing the colliding signals to be retransmitted or by separating the colliding signals. The individual streams corresponding to each of the tags can then be decoded to identify the originally transmitted data from each tag. |
| FILED | Monday, July 31, 2017 |
| APPL NO | 15/664832 |
| ART UNIT | 2683 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10069 (20130101) G06K 7/10158 (20130101) G06K 7/10297 (20130101) Original (OR) Class G06K 19/0709 (20130101) G06K 19/0723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453191 | Shalev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Ronny Y. Shalev (Pepper Pike, Ohio); David L. Wilson (Cleveland Heights, Ohio); Soumya Ray (Cleveland Heights, Ohio) |
| ABSTRACT | Methods and apparatus automatically classify intravascular plaque using features extracted from intravascular optical coherence tomography (IVOCT) imagery. One example apparatus includes an image acquisition circuit that accesses a set of IVOCT images, a pre-processing circuit that generates a blood vessel mask based on the IVOCT images, a feature extraction circuit that defines a three dimensional (3D) volume of interest centered on a location in a member of the set of IVOCT images, a classification circuit that generates a classification based on a probability that a voxel represents a type of plaque, and a visualization circuit that provides a visualization, substantially in real time, of a member of the set of IVOCT images and the classification, where the visualization includes a sector classification image, a labeled image, or a 3D visualization. A prognosis or treatment plan may be provided based on the visualization or the classification. |
| FILED | Wednesday, April 19, 2017 |
| APPL NO | 15/491544 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/627 (20130101) G06K 9/4647 (20130101) G06K 2209/05 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10101 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10455138 | Schillebeeckx et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| ASSIGNEE(S) | Ian Schillebeeckx (San Francisco, California); Robert Pless (Washington, District of Columbia) |
| INVENTOR(S) | Ian Schillebeeckx (St. Louis, Missouri); Robert Pless (St. Louis, Missouri) |
| ABSTRACT | The present disclosure is directed to an approach to solve camera calibration from a single picture of a simply structured light field created by viewing a carefully designed lenticular sheet. The lenticular sheet has different colors visible at different relative orientations and gives linear constraints on the K-1?R matrix which can be decomposed to give the rotation and calibration. The method uses geometric cues from hue measurements and does not require a correspondence between a point in the image and a point on the calibration pattern. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/567746 |
| ART UNIT | 2699 — Search and Capture Special Detail |
| CURRENT CPC | Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 13/36 (20130101) Image Data Processing or Generation, in General G06T 7/80 (20170101) G06T 2200/21 (20130101) G06T 2207/10052 (20130101) Pictorial Communication, e.g Television H04N 5/23212 (20130101) Original (OR) Class H04N 17/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10455608 | Shepard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Skylark Wireless, LLC (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clayton Wells Shepard (Houston, Texas); Lin Zhong (Houston, Texas); Abeer Javed (Houston, Texas); Hang Yu (Houston, Texas) |
| ABSTRACT | Disclosed embodiments include methods for control channel design in many-antenna multi-user (MU) multiple-input multiple-output (MIMO) wireless systems. A beacon comprising an identifier of a many-antenna base station is encoded into a base sequence. A plurality of synchronization sequences is generated based on the encoded base sequence and a set of orthogonal beam sequences. The many-antenna base-station transmits, using a plurality of antennas, the plurality of synchronization sequences in a plurality of beam directions associated with the set of orthogonal beam sequences for synchronization and associated with users without knowledge of channel state information (CSI). |
| FILED | Saturday, April 23, 2016 |
| APPL NO | 15/539997 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 7/046 (20130101) H04B 7/0417 (20130101) H04B 7/0452 (20130101) H04B 7/0456 (20130101) H04B 7/0617 (20130101) H04B 7/0695 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0053 (20130101) H04L 27/2613 (20130101) H04L 27/2692 (20130101) Wireless Communication Networks H04W 48/00 (20130101) H04W 56/001 (20130101) H04W 68/02 (20130101) H04W 72/14 (20130101) Original (OR) Class H04W 72/0446 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10448835 | Pierro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vivonics, Inc. (Bedford, Massachusetts); The Board of Trustees of The University of Arkansas (Little Rock, Arkansas) |
| ASSIGNEE(S) | Vivonics, Inc. (Bedford, Massachusetts); The Board of Trustees of The University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Michele Pierro (Westford, Massachusetts); Kyle Quinn (Fayetteville, Arkansas); Alan Woessner (Fayetteville, Arkansas) |
| ABSTRACT | A contactless system for assessing tissue viability and other hemodynamic parameters includes one or more light sources configured to emit lights at a predetermined wavelength sensitive to hemoglobin concentration associated with spontaneous hemodynamic oscillations at tissue in a predetermined area of a human subject. One or more polarizers are each coupled to one or more of the one or more light sources and are configured to polarize the light to a polarized state such that the polarized light in the polarized state diffuses into the tissue in the predetermined area at a predetermined depth and the polarized light is maintained in the polarized state at the predetermined depth. One or more detectors each including a detector polarizer coupled thereto are configured to discriminate the light maintained in the polarized state and at the predetermined depth and are configured to generate a plurality of frames of the tissue in the predetermined area at the predetermined depth. A controller is coupled to the one or more light sources and the one or more detectors. The controller is configured to: acquire the plurality of frames, select a region of interest having the same coordinates for each of the plurality of frames, average the number of pixels within each region of interest to create a raw reference signal, detrend the raw reference signal to create a detrended raw reference signal, perform frequency domain analysis of the detrended raw reference signal, identify a frequency band of interest associated with the spontaneous hemodynamic oscillations, and perform an inverse fast Fourier transform within the frequency band of interest to generate a reference signal indicative of blood volume oscillations at a selected spontaneous hemodynamic oscillation. For each sample of the reference signal at a predetermined point in time, the controller multiplies the sample by each pixel of a frame at the same predetermined point in time to generate a three-dimensional coordinate matrix including a plurality of correlation matrix frames at each predetermined point in time. The controller adds the plurality of correlation matrix frames at each predetermined point in time to generate a two-dimensional hemodynamic map indicative of the strength of the spontaneous hemodynamic oscillation to assess the viability of the tissue in the predetermined area. |
| FILED | Friday, January 04, 2019 |
| APPL NO | 16/239734 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) Original (OR) Class A61B 5/445 (20130101) A61B 5/14551 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10448954 | McWeeney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GI Windows, Inc. (West Bridgewater, Massachusetts) |
| ASSIGNEE(S) | G.I. Windows, Inc. (West Beidgewater, Massachusetts) |
| INVENTOR(S) | John McWeeney (Brighton, Massachusetts); Marvin Ryou (Melrose, Massachusetts); Padraig Cantillon-Murphy (Danvers, Massachusetts); Jeffrey H. Lang (Danvers, Massachusetts); Christopher Thompson (Needham, Massachusetts) |
| ABSTRACT | Methods and apparatus for creating an anastomosis or fistula between the gallbladder and an adjacent organ are disclosed. First, a parent magnet, typically a permanent magnet, is deployed in the stomach, small intestine, or another organ adjacent to the gallbladder, and a mating daughter material is deployed in the gallbladder in order to create a magnet-compression anastomosis. The gallbladder may then be ablated or otherwise functionally inactivated through the anastomosis. Another aspect of the invention relates to an all-in-one surgical kit that contains all the necessary specialized tools for a surgeon to perform the procedure. |
| FILED | Monday, November 14, 2016 |
| APPL NO | 15/350519 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/11 (20130101) Original (OR) Class A61B 17/1114 (20130101) A61B 2017/00818 (20130101) A61B 2017/00876 (20130101) A61B 2017/1117 (20130101) A61B 2017/1132 (20130101) A61B 2017/1139 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10448956 | Gordon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF DEFENSE (Bethesda, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Chad Gordon (Lutherville, Maryland); Mehran Armand (Fulton, Maryland); Ryan Murphy (Columbia, Maryland); Gerald Grant (Goshen, Kentucky); Peter Liacouras (North Potomac, Maryland); Kevin Wolfe (Lutherville, Maryland); Ehsan Basafa (Baltimore, Maryland) |
| ABSTRACT | A method for computer-assisted planning of a transplant surgery is provided. The method includes obtaining a computer-readable representation of a donor and recipient skeletal fragment; determining surgical cutting planes on the computer-readable representation of the donor skeletal fragment from which a portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment will be harvested; determining virtual cutting guides; performing a virtual osteotomy to separate the portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment from a remainder portion of the donor skeletal fragment based on a position of the virtual cutting guides that are attached to the computer-readable representation of the donor skeletal fragment; positioning the donor skeletal fragment within a transplant region of the recipient skeletal fragment; and creating a hybrid computer-readable representation comprising the recipient skeletal fragment and the portion of the donor skeletal. |
| FILED | Wednesday, November 26, 2014 |
| APPL NO | 15/100215 |
| ART UNIT | 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/15 (20130101) Original (OR) Class A61B 17/176 (20130101) A61B 17/1695 (20130101) A61B 17/1739 (20130101) A61B 17/8085 (20130101) A61B 34/10 (20160201) A61B 34/20 (20160201) A61B 2034/105 (20160201) A61B 2034/108 (20160201) A61B 2034/2051 (20160201) A61B 2034/2055 (20160201) A61B 2034/2065 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2803 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) G06F 19/3481 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449170 | Venn-Watson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephanie Venn-Watson (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Stephanie Venn-Watson (San Diego, California) |
| ABSTRACT | Compositions including an odd chain fatty acid, and salts and derivatives thereof, and methods for metabolic syndrome treatment and prophylaxis are provided, including compositions and methods for treating diabetes, obesity, hyperferritinemia, elevated insulin, glucose intolerance, dyslipidemia and related conditions. Methods for the diagnosis and monitoring of metabolic syndrome are also provided. |
| FILED | Monday, June 25, 2018 |
| APPL NO | 16/017447 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449171 | Venn-Watson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephanie Venn-Watson (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Stephanie Venn-Watson (San Diego, California) |
| ABSTRACT | Compositions including an odd chain fatty acid, and salts and derivatives thereof, and methods for metabolic syndrome treatment and prophylaxis are provided, including compositions and methods for treating diabetes, obesity, hyperferritinemia, elevated insulin, glucose intolerance, dyslipidemia and related conditions. Methods for the diagnosis and monitoring of metabolic syndrome are also provided. |
| FILED | Tuesday, June 26, 2018 |
| APPL NO | 16/018922 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449186 | Watt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | David S. Watt (Lexington, Kentucky); Chunming Liu (Lexington, Kentucky); Vitaliy M. Sviripa (Lexington, Kentucky); Wen Zhang (Lexington, Kentucky); Markos Leggas (Lexington, Kentucky) |
| ABSTRACT | Halogenated phenylethynyl-substituted heterocycles that possess either an N-alkylamino or N,N-dialkylamino group attached to the heterocycle or halogenated phenylethynyl-substituted benzenes that a nitrogen-containing heterocycle attached to the benzene inhibit the proliferation cancer cells and are useful antineoplastic agents. |
| FILED | Thursday, May 10, 2018 |
| APPL NO | 15/976643 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/45 (20130101) Original (OR) Class A61K 31/47 (20130101) A61K 31/404 (20130101) A61K 31/416 (20130101) A61K 31/437 (20130101) A61K 31/472 (20130101) A61K 31/495 (20130101) A61K 31/4418 (20130101) A61K 31/4439 (20130101) A61K 31/4706 (20130101) A61K 31/4725 (20130101) A61K 31/4965 (20130101) A61K 31/5375 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449234 | Chauhan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Sunil Chauhan (Cambridge, Massachusetts); Reza Dana (Newton, Massachusetts) |
| ABSTRACT | This application discloses ophthalmic formulations and methods for treating and preventing corneal haze and scarring with an hepatocyte growth factor (HGF) agent. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/759203 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/1833 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Peptides C07K 14/00 (20130101) C07K 14/4753 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449267 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy Kuan-Ta Lu (Cambridge, Massachusetts); Chao Zhong (Bedford, Massachusetts) |
| ABSTRACT | Compositions, methods, and kits are provided which involve novel fusion protein-based adhesives for use in medical and marine applications. In some aspects, the novel fusion proteins comprise an adhesive domain (e.g., derived from an adhesive protein of a marine organism) and an amyloid domain (e.g., derived from a bacterial amyloid protein). Also provided are copolymers and fibers of the fusion proteins. |
| FILED | Thursday, November 13, 2014 |
| APPL NO | 14/540872 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/001 (20130101) A61L 24/108 (20130101) Original (OR) Class Peptides C07K 14/78 (20130101) C07K 14/245 (20130101) C07K 14/43504 (20130101) C07K 14/43509 (20130101) C07K 2319/00 (20130101) C07K 2319/70 (20130101) C07K 2319/73 (20130101) C07K 2319/735 (20130101) Derivatives of Natural Macromolecular Compounds C08H 1/00 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 5/00 (20130101) C09J 189/00 (20130101) C09J 2489/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449359 | Kahana et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Michael Kahana (Merion Station, Pennsylvania); Daniel S. Rizzuto (Philadelphia, Pennsylvania) |
| ABSTRACT | A method for delivering electrical stimulation to alter a cognitive state of a user, the method comprising: monitoring a brain signal from the user via one or more intracranial electrodes implanted in the brain of the user while the user is presented with a stimulus; comparing the brain signal to a testing phase biomarker, wherein the testing phase biomarker is derived from a cognitive test performed on a contributor during a testing phase; delivering electrical stimulation to a brain of the user based on the comparing step to steer the brain of the user towards a high performance cognitive state. |
| FILED | Friday, January 22, 2016 |
| APPL NO | 15/545927 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0484 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) A61N 1/0534 (20130101) A61N 1/36064 (20130101) A61N 1/36067 (20130101) A61N 1/36082 (20130101) Original (OR) Class A61N 1/36135 (20130101) Electric Digital Data Processing G06F 19/3481 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450573 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Andrew L. Chang (Redwood City, California); Christina D. Smolke (Menlo Park, California) |
| ABSTRACT | Aptamers that specifically bind to ligands of folinic acid, a folate, and derivatives thereof (which may be referred to herein as ligands) are provided, and compositions and methods of use thereof. The aptamers and switches of the invention provide biological sensing capability for detecting the ligands, and are effective in sensing in vitro and in vivo. By specific sensing of the ligand, the aptamers of the invention provide a means of engineering an inducible gene regulatory system that enables dose-dependent control over gene expression in response to the ligand, in vivo and in vitro. |
| FILED | Thursday, August 13, 2015 |
| APPL NO | 15/502694 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/12 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) C12N 2310/121 (20130101) C12N 2310/122 (20130101) C12N 2310/141 (20130101) C12N 2310/351 (20130101) C12N 2310/3519 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450599 | Pierce et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Niles A. Pierce (Pasadena, California); Harry Ming Tak Choi (Pasadena, California) |
| ABSTRACT | The present disclosure relates to methods and compositions involving HCR reactions that involve initiators that are split into two or more parts. Effective HCR is dependent upon two or more of these split initiators being brought into proximity (e.g., via binding events mediated by a target) such that a full initiator is formed that is capable of triggering HCR signal amplification. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/639100 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450609 | Sukumar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Saraswati Sukumar (Columbia, Maryland); Mary Jo Fackler (Hunt Valley, Maryland); Wei Wen Teo (Johor Bahru Johor, Malaysia); Zoila Areli Lopez Bujanda (Bethesda, Maryland); Antonio Wolff (Baltimore, Maryland) |
| ABSTRACT | The cMethDNA method of the present invention is a novel modification of the QM-MSP method (U.S. Pat. No. 8,062,849), specifically intended to quantitatively detect tumor DNA (or other circulating DNAs) in fluids such as serum or plasma at the lowest copy number yet reported. Unique compared to any other PCR-based assay, a small number of copies of a synthetic polynucleotide standard (STDgene) is added to an aliquot of patient serum with standards for a plurality of genes of interest (TARGETgene). Once total DNA is purified PCR is performed wherein the STDgene and the TARGETgene are co-amplified with the same external primer set, and the amplicons present in a dilution of the first PCR reaction are subjected to real time PCR, and quantified for each gene. Methods of making the STDgene standards and the use of the cMethDNA methods and kits containing the same are disclosed. |
| FILED | Wednesday, May 22, 2013 |
| APPL NO | 14/402434 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2523/125 (20130101) C12Q 2525/301 (20130101) C12Q 2545/114 (20130101) C12Q 2563/107 (20130101) C12Q 2565/1015 (20130101) C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450621 | Abrahams |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Rachel Ann Abrahams (Crestview, Florida) |
| ABSTRACT | A low alloy, high performance steel having high impact toughness and high ductility, as well as methods of making and heat treating the alloy, are provided. The alloy steel composition consists essentially of about 0.24% to about 0.32% carbon, about 2.00% to about 3.00% chromium, about 0.50% to about 1.50% molybdenum, about 0.05% to about 0.35% vanadium, about 1.00% manganese or less, about 3.00% nickel or less, about 1.50% silicon or less, with minimal impurities, and balance consisting essentially of iron, wherein % is weight percent based on the entire weight of the alloy steel composition. The impurities may include about 0.20% copper or less, about 0.015% phosphorous or less, about 0.012% sulfur or less, about 0.02% calcium or less, about 0.15% nitrogen or less, and/or about 0.025% aluminum or less. Also disclosed is a hardened and tempered article that has high impact toughness, as well as other favorable physical properties. |
| FILED | Friday, May 20, 2016 |
| APPL NO | 15/160221 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/18 (20130101) C21D 1/28 (20130101) C21D 1/60 (20130101) C21D 6/004 (20130101) Original (OR) Class C21D 6/005 (20130101) C21D 6/008 (20130101) C21D 8/0226 (20130101) C21D 2211/001 (20130101) C21D 2211/008 (20130101) Alloys C22C 38/001 (20130101) C22C 38/002 (20130101) C22C 38/02 (20130101) C22C 38/04 (20130101) C22C 38/06 (20130101) C22C 38/42 (20130101) C22C 38/44 (20130101) C22C 38/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450652 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Haitao Liu (Pittsburgh, Pennsylvania); Feng Zhou (New York, New York) |
| ABSTRACT | A method of forming a carbonized composition includes providing an organic composition, forming a protective layer over the organic composition, increasing temperature to carbonize the organic composition and for a period of time to form the carbonized composition, and removing the protective layer from the carbonized composition. |
| FILED | Friday, April 14, 2017 |
| APPL NO | 15/487696 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/90 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/04 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/45525 (20130101) Original (OR) Class C23C 18/1283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450661 | DiMascio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Felice DiMascio (Rock Hill, Connecticut); Heather D. Willauer (Fairfax Station, Virginia); Dennis R. Hardy (California, Maryland); Frederick Williams (Accokeek, Maryland); M. Kathleen Lewis (Lake Ariel, Pennsylvania) |
| ABSTRACT | A method for using an electrochemical cell to continuously acidify alkaline water sources and recover carbon dioxide with simultaneous continuous hydrogen gas production. The electrochemical cell has a center compartment, an electrolyte-free anode compartment having a mesh anode in direct contact with an ion permeable membrane, an endblock in direct contact with the anode where the endblock provides a gas escape route behind the anode, an electrolyte-free cathode compartment having a mesh cathode in direct contact with an ion permeable membrane, and an endblock in direct contact with the cathode where the endblock provides a gas escape route behind the cathode. Current applied to the electrochemical cell for generating hydrogen gas also lowers the pH of the alkaline water to produce carbon dioxide with no additional current or power. |
| FILED | Tuesday, June 06, 2017 |
| APPL NO | 15/614855 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/50 (20170801) Treatment of Water, Waste Water, Sewage, or Sludge C02F 2001/46185 (20130101) C02F 2201/46115 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 1/10 (20130101) Original (OR) Class C25B 9/10 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450880 | Banks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Anton G. Banks (Manchester, Connecticut); Leah M. Collins (Essex, Connecticut); Gary J. Larson (Madison, Connecticut); Thomas P. Dziuba (Northford, Connecticut); Scott A. Kovach (Higganum, Connecticut) |
| ABSTRACT | A baffle assembly includes a collar with a port and a baffle positioned in the port. The baffle includes two ends, a hollow body, and a weld connecting the baffle to the collar, and the collar continuously surrounds the body of the baffle. |
| FILED | Thursday, August 04, 2016 |
| APPL NO | 15/228573 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/188 (20130101) F01D 5/189 (20130101) F01D 9/02 (20130101) F01D 9/065 (20130101) Original (OR) Class F01D 25/005 (20130101) Jet-propulsion Plants F02K 3/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/50 (20130101) F05D 2230/54 (20130101) F05D 2230/60 (20130101) F05D 2230/232 (20130101) F05D 2230/233 (20130101) F05D 2230/234 (20130101) F05D 2230/235 (20130101) F05D 2240/11 (20130101) F05D 2240/81 (20130101) F05D 2240/126 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450894 | Witlicki et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Russell B. Witlicki (Wethersfield, Connecticut); Joseph J. Sodaro (Vernon, Connecticut); Denman H. James (West Hartford, Connecticut) |
| ABSTRACT | Aspects of the disclosure are directed to a system associated with an engine, comprising: a bearing compartment, a scavenge line coupled to the bearing compartment at a first end of the scavenge line that receives a fluid via the first end of the scavenge line, a fluid pump coupled to the scavenge line at a second end of the scavenge line to receive the fluid, and a flow control valve having a variable flow area and disposed in the scavenge line to control flow of the fluid in the scavenge line and the fluid pump. |
| FILED | Monday, November 28, 2016 |
| APPL NO | 15/362049 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/18 (20130101) F01D 25/32 (20130101) F01D 25/168 (20130101) F01D 25/186 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/50 (20130101) F05D 2260/98 (20130101) F05D 2260/602 (20130101) F05D 2270/304 (20130101) Lubricating F16N 7/32 (20130101) F16N 7/40 (20130101) F16N 2210/02 (20130101) F16N 2210/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450895 | Amadon |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Colin G. Amadon (Kennebunk, Maine) |
| ABSTRACT | A stator includes a plurality of stator vanes and a shroud operably connected to the stator vanes. The shroud includes one or more positioning tabs configured to engage one or more corresponding alignment features of a mating component to radially position the shroud at the mating component, the one or more shroud positioning tabs position the outer shroud to define a radial tip clearance between an outer shroud and an adjacent rotor of the gas turbine engine. A gas turbine engine includes a stator and case assembly in fluid communication with a combustor. The stator and case assembly includes a stator located at a case. The stator has a plurality of stator vanes and a shroud including one or more positioning tabs configured to engage one or more corresponding case alignment features to radially position the shroud at the case. |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/136130 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 9/042 (20130101) F01D 25/24 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/12 (20130101) F05D 2240/14 (20130101) F05D 2240/35 (20130101) F05D 2260/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450943 | Geyko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vasily Geyko (Hamilton Township, New Jersey); Nathaniel Fisch (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Vasily Geyko (Hamilton Township, New Jersey); Nathaniel Fisch (Princeton, New Jersey) |
| ABSTRACT | An internal combustion engine is disclosed and includes a main cylinder and main piston that are relatively axially displaceable along a main axis to define a variable volume main working chamber. At least one valve is configured to admit air and fuel into the working chamber forming an air/fuel mixture. The main cylinder is configured to cause the air/fuel mixture in the main cylinder to spin rapidly enough to cause a substantive change in the heat capacity of the air/fuel mixture creating a spinning air/fuel mixture. The main cylinder and main piston are configured to compress the spinning air/fuel mixture to create an ignitable spinning air/fuel mixture. The spinning air/fuel mixture is ignited and the main cylinder and main piston are configured to extract mechanical energy from the ignited spinning air/fuel mixture. An exhaust valve is configured to exhaust combustion products from the main working chamber. |
| FILED | Thursday, March 26, 2015 |
| APPL NO | 14/669936 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 31/02 (20130101) Original (OR) Class F02B 31/04 (20130101) F02B 75/28 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/146 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451003 | Sutterfield et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | David L. Sutterfield (Greenwood, Indiana); Randall E. Yount (Indianapolis, Indiana) |
| ABSTRACT | A nozzle support system for a nozzle of a gas turbine includes an outer ring, an inner ring disposed within the outer ring, and a plurality of links pivotally attaching the outer ring to the inner ring. Each one of the links may have an outer end that is pivotally attached to the outer ring, and each one of the links may have an inner end that is pivotally attached to the inner ring, such that the inner ring moves along a longitudinal axis of the outer ring. |
| FILED | Tuesday, October 27, 2015 |
| APPL NO | 14/923669 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 9/042 (20130101) F01D 25/16 (20130101) F01D 25/28 (20130101) F01D 25/246 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 7/20 (20130101) F02C 7/28 (20130101) Jet-propulsion Plants F02K 1/78 (20130101) Original (OR) Class F02K 1/80 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/35 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 1/00 (20130101) F16B 2001/0078 (20130101) Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 11/06 (20130101) F16M 11/2007 (20130101) F16M 13/02 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451168 | Ture et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Cody Michael Ture (Fairport, New York); David Ortiz (Rochester, New York); Carl S. Byington (Pittsford, New York); Carl Palmer (Pittsford, New York); John R. Farnach (Henrietta, New York); Ryan Brewer (Rochester, New York) |
| ABSTRACT | A fluid condition monitoring device includes a sensing assembly including a sensor and a transducer, the sensor to sense a property of the fluid and the transducer to apply a test signal to the fluid and receive a return signal from the fluid; a control assembly coupled to the sensing assembly, the control assembly including a controller and an input/output interface, the controller interfacing with the transducer to generate fluid condition information in response to the return signal; and an interface assembly coupled to the control assembly, the interface assembly including a connection to the input/output interface to transmit the fluid condition information to an external system. |
| FILED | Tuesday, January 05, 2016 |
| APPL NO | 15/555203 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 35/00 (20130101) B64D 45/00 (20130101) B64D 2045/0085 (20130101) Lubricating of Machines or Engines in General; Lubricating Internal Combustion Engines; Crankcase Ventilating F01M 11/10 (20130101) Gearing F16H 57/0405 (20130101) Original (OR) Class Lubricating F16N 29/00 (20130101) F16N 2200/02 (20130101) F16N 2200/12 (20130101) F16N 2200/20 (20130101) F16N 2210/08 (20130101) F16N 2210/12 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/06 (20130101) G01N 33/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451169 | Maners et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | ROLLS-ROYCE CORPORATION (Indianapolis, Indiana) |
| INVENTOR(S) | Brian Scott Maners (Indianapolis, Indiana); David Russell Bockmiller (Indianapolis, Indiana) |
| ABSTRACT | The present disclosure provides a lubricating system for a dual splined hollow shaft. A fluid dam is formed circumferentially within the hollow shaft to control the lubrication of the dual splines. The fluid dam includes a pair of sidewalls extending radially inward from the inner wall of the hollow shaft to a height defined by a top wait. A channel formed through the pair of sidewalls permits the movement of lubricant between splines of the hollow shaft. An egress port extends from the top wall of the dam through the outer wall of the hollow shaft to permit lubricant to exit the hollow shaft. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 15/610021 |
| ART UNIT | 3654 — Material and Article Handling |
| CURRENT CPC | Couplings for Transmitting Rotation; Clutches; Brakes F16D 2001/103 (20130101) F16D 2300/06 (20130101) Gearing F16H 57/043 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451321 | Ihnfeldt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Engineering and Research, L.L.C. (San Diego, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | General Engineering and Research, L.L.C. (San Diego, California); The Regents of The University of California (Oakland, California) |
| INVENTOR(S) | Robin Veronica Ihnfeldt (San Diego, California); Xia Xu (San Diego, California); Renkun Chen (San Diego, California); Sungho Jin (San Diego, California); Jianlin Zheng (La Jolla, California) |
| ABSTRACT | This invention relates to a cooling device which utilizes both thermoelectric and magnetocaloric mechanisms for enhanced cooling applications. Using high thermal conductivity magnetocaloric composites in conjunction with thermoelectric elements acting as thermal switches which are electrically coupled to a magnetization and demagnetization cycle enables the use of larger quantities of magnetocaloric material, and high efficiency solid state cooling can be achieved. Solid state cooling devices are useful for a variety of industrial applications which require cooling, such as, but not limited to cooling of microelectronic devices, cooling on space platforms, etc. |
| FILED | Friday, September 01, 2017 |
| APPL NO | 15/694616 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) Original (OR) Class F25B 2321/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/14 (20130101) H01L 35/32 (20130101) H01L 37/04 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451421 | Sanders et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Glen A. Sanders (Scottsdale, Arizona); Clarence Eugene Laskoskie (Scottsdale, Arizona); Chellappan Narayanan (Phoenix, Arizona); Lee K. Strandjord (Tonka Bay, Minnesota) |
| ABSTRACT | An optical resonator is provided. The optical resonator comprises: an optical resonator coil comprising a first port and a second port; wherein the optical resonator coil comprises antiresonant nodeless fiber; a resonator loop closure optics system; and wherein the antiresonant nodeless fiber has a length such that the resonant frequencies the optical resonator of the desired polarization state of light and of the undesired polarization state of light are separated by between a tenth of a free spectral range and nine tenths of a free spectral range to minimize gyroscope errors. |
| FILED | Friday, April 13, 2018 |
| APPL NO | 15/952971 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/722 (20130101) Original (OR) Class G01C 19/727 (20130101) Optical Elements, Systems, or Apparatus G02B 6/0096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451482 | Martini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Joerg Martini (San Francisco, California); Marshall W. Bern (San Carlos, California); Noble M. Johnson (Menlo Park, California); Peter Kiesel (Palo Alto, California); Doron Kletter (San Mateo, California); Bowen Cheng (Atherton, California); Michael I. Recht (Mountain View, California) |
| ABSTRACT | A system is configured to determine a color distribution of an object moving along a flow direction relative to a spatial filter. The light emanating from the object is time modulated according to the mask features of the spatial filter. First and second detectors are arranged to sense the modulated light. The first detector senses light having a first wavelength spectrum and generates a first electrical output signal in response to the sensed light. The second detector light senses light having a second wavelength spectrum and generates a second electrical output signal in response to the sensed light. Signals from the first and second detectors include information about color distribution of the object. |
| FILED | Friday, February 14, 2014 |
| APPL NO | 14/181571 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/51 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/147 (20130101) G01N 15/1429 (20130101) G01N 15/1434 (20130101) G01N 15/1459 (20130101) G01N 15/1475 (20130101) G01N 2015/1006 (20130101) G01N 2015/1447 (20130101) G01N 2015/1472 (20130101) G01N 2015/1477 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451483 | Pezzaniti |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Polaris Sensor Technologies, Inc. (Huntsville, Alabama) |
| ASSIGNEE(S) | Polaris Sensor Technologies, Inc. (Huntsville, Alabama) |
| INVENTOR(S) | J. Larry Pezzaniti (Huntsville, Alabama) |
| ABSTRACT | A short wave infrared polarimeter comprising a pixelated polarizer array and an Indium-Gallium-Arsenide (“InGaAs”) focal plane array. The short wave infrared polarimeter optionally includes a micro-lens array and/or an aperture layer. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/024415 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0208 (20130101) G01J 3/0229 (20130101) G01J 4/02 (20130101) Original (OR) Class G01J 4/04 (20130101) G01J 5/58 (20130101) G01J 2005/586 (20130101) Optical Elements, Systems, or Apparatus G02B 3/0006 (20130101) G02B 5/30 (20130101) G02B 5/3025 (20130101) G02B 5/3058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451489 | Bousquet et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Rob A. Bousquet (Waltham, Massachusetts); Murali Chaparala (Newton, Massachusetts); Brent M. Hollosi (Medford, Massachusetts); Zachary R. Smigelski (Hyde Park, Massachusetts); Wes Uy (Quincy, Massachusetts); Geremy Freifeld (Waltham, Massachusetts) |
| ABSTRACT | A thermal event sensor includes a charge storage component formed on a substrate, configured to hold an initial charge, and configured to lose charge at a rate dependent upon temperature. A sensing interface is coupled to the charge storage component and a readout mechanism is coupled to the sensing interface. The readout mechanism senses a remaining charge on the charge storage component and provides a readout value indicative of the remaining charge. |
| FILED | Friday, July 08, 2016 |
| APPL NO | 15/205401 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/01 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/088 (20130101) H01L 29/7886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451538 | Jalali et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Bahram Jalali (Los Angeles, California); Eric Diebold (Los Angeles, California); Brandon Buckley (Los Angeles, California) |
| ABSTRACT | An imaging flow cytometry apparatus and method which allows registering multiple locations across a cell, and/or across multiple flow channels, in parallel using radio-frequency-tagged emission (FIRE) coupled with a parallel optical detection scheme toward increasing analysis throughput. An optical source is modulated by multiple RF frequencies to produce an optical interrogation beam having a spatially distributed beat frequency. This beam is directed to one or more focused streams of cells whose responsive fluorescence, in different frequencies, is registered in parallel by an optical detector. |
| FILED | Monday, January 14, 2019 |
| APPL NO | 16/247426 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 15/1459 (20130101) G01N 15/1484 (20130101) G01N 21/64 (20130101) G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 33/537 (20130101) G01N 2015/1006 (20130101) G01N 2015/1477 (20130101) G01N 2021/6421 (20130101) G01N 2201/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451548 | Gemp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Kevin Gemp (Falls Church, Virginia); Ariel Schlamm (Washington, District of Columbia); Christopher Miller (Darnestown, Maryland); Shannon Jordan (Fairfax, Virginia); Marin Halper (Washington, District of Columbia); Brent Bartlett (Falls Church, Virginia) |
| ABSTRACT | A system for generating reflectance values for a target that includes a plurality of electromagnetic radiation sources for irradiating the target, an imager for generating a plurality of digital representations of the target that includes an array of filter elements for filtering electromagnetic radiation reflected by the target through an array of filter elements, and a detector for detecting the filtered electromagnetic radiation at an array of detection elements. The system includes processors for determining a set of reflectance values for a portion of the target based on a first digital representation of the target generated in response to irradiation of the target with radiation of a first wavelength band and a second digital representation of the target generated in response to irradiation of the target with radiation of a second wavelength band. |
| FILED | Friday, January 15, 2016 |
| APPL NO | 14/997300 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/27 (20130101) G01N 21/55 (20130101) Original (OR) Class G01N 2201/0612 (20130101) G01N 2201/0621 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451883 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Magic Leap, Inc. (Plantation, Florida) |
| ASSIGNEE(S) | Magic Leap, Inc. (Plantation, Florida) |
| INVENTOR(S) | Chunyu Gao (Tucson, Arizona); Yuxiang Lin (Tucson, Arizona); Hong Hua (Tucson, Arizona) |
| ABSTRACT | The present invention comprises a compact optical see-through head-mounted display capable of combining, a see-through image path with a virtual image path such that the opaqueness of the see-through image path can be modulated and the virtual image occludes parts of the see-through image and vice versa. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196886 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 13/06 (20130101) G02B 25/001 (20130101) G02B 27/144 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 27/283 (20130101) G02B 27/1066 (20130101) G02B 2027/015 (20130101) G02B 2027/0118 (20130101) G02B 2027/0145 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 37/02 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Pictorial Communication, e.g Television H04N 5/2258 (20130101) H04N 5/23238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10452370 | Davidson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia); Jack W. Davidson (Charlottesville, Virginia); Clark Lynch Coleman (Charlottesville, Virginia) |
| ASSIGNEE(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | Jack W. Davidson (Charlottesville, Virginia); Clark Lynch Coleman (Charlottesville, Virginia); Jason D. Hiser (Charlottesville, Virginia); Anh Nguyen-Tuong (Charlottesville, Virginia) |
| ABSTRACT | According to some illustrative embodiments of the invention, a method is performed that includes using a representation of a computer software program, using identified addresses which correspond to a part of the representation, and converting the representation into a created binary program, which includes reserving spaces at the identified addresses in the created binary program's address space at the same addresses as the identified addresses in the representation. |
| FILED | Friday, January 08, 2016 |
| APPL NO | 15/542214 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/44 (20130101) G06F 8/48 (20130101) G06F 8/52 (20130101) Original (OR) Class G06F 8/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10452466 | Mitchell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Tyler J. Mitchell (Ithaca, New York); Kenneth McVearry (Dewitt, New York) |
| ABSTRACT | An example method includes receiving one or more cross-platform system maintenance rules that are generated by and sent from a central server computing system, determining a type of software operating system currently being executed by a client computing system, determining, based on the one or more cross-platform system maintenance rules and further based on the type of software operating system, one or more platform-specific system maintenance rules that specify one or more platform-specific system maintenance operations and scheduling information, and determining, based on scheduling information identified by the one or more platform-specific system maintenance rules, a schedule indicating when to perform the one or more platform-specific system maintenance operations. The example method includes initiating performance of the one or more platform-specific system maintenance operations in accordance with the schedule, collecting one or more results, and generating and sending at least one summary report. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 15/826527 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/079 (20130101) Original (OR) Class G06F 11/301 (20130101) G06F 11/302 (20130101) G06F 11/0709 (20130101) G06F 11/0712 (20130101) G06F 11/0751 (20130101) G06F 11/0769 (20130101) G06F 11/0793 (20130101) G06F 11/3006 (20130101) G06F 11/3495 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10452621 | Medard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Muriel Medard (Belmont, Massachusetts); Ulric J. Ferner (Cambridge, Massachusetts); Tong Wang (Cambridge, Massachusetts) |
| ABSTRACT | Multi-resolution encoded files are stored on a plurality of disk drives using systematic network coded storage. In some embodiments, the stored files are used to provide video streaming services for users. |
| FILED | Wednesday, February 08, 2017 |
| APPL NO | 15/427536 |
| ART UNIT | 2159 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/1827 (20190101) Original (OR) Class Pictorial Communication, e.g Television H04N 21/2312 (20130101) H04N 21/23439 (20130101) H04N 21/234327 (20130101) H04N 21/234363 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453654 | Kobernik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PHOENIX LLC (Monona, Wisconsin) |
| ASSIGNEE(S) | PHOENIX LLC (Monona, Wisconsin) |
| INVENTOR(S) | Arne Kobernik (Monona, Wisconsin); Carl Sherven (Monona, Wisconsin); Casey Lamers (Monona, Wisconsin); Chris Seyfert (Monona, Wisconsin); Evan Sengbusch (Monona, Wisconsin); Gabriel Becerra (Monona, Wisconsin); Jin Lee (Monona, Wisconsin); Logan Campbell (Monona, Wisconsin); Mark Thomas (Monona, Wisconsin); Michael Taylor (Monona, Wisconsin); Preston Barrows (Monona, Wisconsin); Ross Radel (Monona, Wisconsin); Tye Gribb (Monona, Wisconsin) |
| ABSTRACT | Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196697 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/32082 (20130101) Original (OR) Class H01J 41/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453775 | Carlson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SA Photonics, Inc. (Los Gatos, California) |
| ASSIGNEE(S) | SA Photonics, Inc. (Los Gatos, California) |
| INVENTOR(S) | Mark Carlson (Campbell, California) |
| ABSTRACT | A thermoelectric module for cooling a heat source includes multiple major sections, each major section including multiple minor sections. Each minor section includes one or more thermoelectric cooler (TEC) units including P-type and N-type semiconductors. Each major section also includes a single output terminal commonly connected to the minor sections, where the output terminal is configured to provide a same reference voltage signal to each of the minor sections. Each major section also comprises multiple input terminals, where each input terminal is separately connected to one of the minor sections and each input terminal is configured to provide a separate input voltage signal to each of the minor sections. The module also comprises a controller configured to independently control each reference voltage signal applied to each major section, and independently control each input voltage signal applied to each input terminal of each minor section within each major section. |
| FILED | Wednesday, June 10, 2015 |
| APPL NO | 14/736202 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/38 (20130101) Original (OR) Class H01L 35/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453893 | Ning et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Cun-Zheng Ning (Chandler, Arizona); Sunay Turkdogan (Tempe, Arizona); Zhicheng Liu (Tempe, Arizona); Fan Fan (Tempe, Arizona) |
| ABSTRACT | Some embodiments include a method. The method can include: providing a carrier substrate; forming a first device material over the carrier substrate; and after forming the first device material over the carrier substrate, transforming the first device material into a second device material. Meanwhile, the transforming the first device material into the second device material can include: causing a cationic exchange in the first device material; and causing an anionic exchange in the first device material. The causing the cationic exchange in the first device material and the causing the anionic exchange in the first device material can occur approximately simultaneously. Other embodiments of related methods and systems are also disclosed. |
| FILED | Friday, December 01, 2017 |
| APPL NO | 15/829551 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/04 (20130101) H01L 21/225 (20130101) H01L 21/0256 (20130101) H01L 21/0262 (20130101) H01L 21/265 (20130101) H01L 21/02557 (20130101) H01L 21/02568 (20130101) H01L 21/02664 (20130101) H01L 27/15 (20130101) Original (OR) Class H01L 27/153 (20130101) H01L 33/005 (20130101) H01L 33/28 (20130101) H01L 33/0087 (20130101) H01L 33/0095 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/3018 (20130101) H01S 5/4093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453977 | Meyer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Governement of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jerry R. Meyer (Catonsville, Maryland); Igor Vurgaftman (Severna Park, Maryland); Chadwick Lawrence Canedy (Washington, District of Columbia); William W. Bewley (Falls Church, Virginia); Chul Soo Kim (Springfield, Virginia); Charles D. Merritt (Fairfax, Virginia); Michael V. Warren (Arlington, Virginia); Mijin Kim (Springfield, Virginia) |
| ABSTRACT | Resonant-cavity infrared photodetector (RCID) devices that include a thin absorber layer contained entirely within the resonant cavity. In some embodiments, the absorber is a single type-II InAs—GaSb interface situated between an AlSb/InAs superlattice n-type region and a p-type AlSb/GaSb region. In other embodiments, the absorber region comprises quantum wells formed on an upper surface of the n-type region. In other embodiments, the absorber region comprises a “W”-structured quantum well situated between two barrier layers, the “W”-structured quantum well comprising a hole quantum well sandwiched between two electron quantum wells. In other embodiments, the RCID includes a thin absorber region and an nBn or pBp active core within a resonant cavity. In some embodiments, the RCID is configured to absorb incident light propagating in the direction of the epitaxial growth of the RCID structure, while in other embodiments, it absorbs light propagating in the epitaxial plane of the structure. |
| FILED | Tuesday, April 09, 2019 |
| APPL NO | 16/378600 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) G01N 21/552 (20130101) G01N 21/3504 (20130101) G01N 21/7746 (20130101) Optical Elements, Systems, or Apparatus G02B 6/124 (20130101) G02B 6/12004 (20130101) G02B 2006/12061 (20130101) G02B 2006/12078 (20130101) G02B 2006/12123 (20130101) G02B 2006/12138 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/105 (20130101) H01L 31/109 (20130101) H01L 31/02327 (20130101) Original (OR) Class H01L 31/03046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453979 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FLIR Systems, Inc. (Wilsonville, Oregon) |
| ASSIGNEE(S) | FLIR SYSTEM, INC. (Wilsonville, Oregon) |
| INVENTOR(S) | Edward K. Huang (Thousand Oaks, California); Andrew D. Hood (Ventura, California) |
| ABSTRACT | Materials and methods may be provided for short-wave infrared (SWIR) superlattice materials. The superlattice material includes a first sub-layer comprising InAs, and a second sub-layer adjacent to the first sub-layer including AlSb, AlAsSb, or InAlAsSb. |
| FILED | Monday, December 19, 2016 |
| APPL NO | 15/384052 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1446 (20130101) H01L 31/109 (20130101) H01L 31/1844 (20130101) H01L 31/03046 (20130101) H01L 31/035236 (20130101) H01L 31/035263 (20130101) Original (OR) Class Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/44 (20141201) Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453984 | Yao |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WAVEFRONT HOLDINGS, LLC (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | WAVEFRONT HOLDINGS, LLC (Basking Ridge, New Jersey) |
| INVENTOR(S) | Jie Yao (Plainsboro, New Jersey) |
| ABSTRACT | Disclosed are phototransistors, and more specifically a detector that includes two or more phototransistors, conductively isolated from each other. Embodiments also relate to methods of making the detector. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/467478 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/146 (20130101) H01L 27/1463 (20130101) H01L 27/14603 (20130101) H01L 27/14609 (20130101) H01L 27/14694 (20130101) H01L 31/1105 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10454006 | Shur et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sensor Electronic Technology, Inc. (Columbia, South Carolina) |
| ASSIGNEE(S) | Sensor Electronic Technology, Inc. (Columbia, South Carolina) |
| INVENTOR(S) | Michael Shur (Latham, New York); Maxim S. Shatalov (Columbia, South Carolina); Alexander Dobrinsky (Loudonville, New York) |
| ABSTRACT | A semiconductor structure including an anodic aluminum oxide layer is described. The anodic aluminum oxide layer can include a plurality of pores extending to an adjacent surface of the semiconductor structure. A filler material can penetrate at least some of the plurality of pores and directly contact the surface of the semiconductor structure. In an illustrative embodiment, multiple types of filler material at least partially fill the pores of the aluminum oxide layer. |
| FILED | Friday, August 19, 2016 |
| APPL NO | 15/241425 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 11/16 (20130101) C25D 11/24 (20130101) C25D 11/045 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02178 (20130101) H01L 21/02203 (20130101) H01L 21/02258 (20130101) H01L 33/007 (20130101) H01L 33/12 (20130101) H01L 33/32 (20130101) H01L 33/42 (20130101) H01L 33/44 (20130101) H01L 33/58 (20130101) Original (OR) Class H01L 33/0075 (20130101) H01L 33/145 (20130101) H01L 33/382 (20130101) H01L 33/387 (20130101) H01L 33/405 (20130101) H01L 2933/0016 (20130101) H01L 2933/0058 (20130101) H01L 2933/0083 (20130101) H01L 2933/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10454177 | Kozyrev |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander B. Kozyrev (Rockville, Maryland) |
| ABSTRACT | The current disclosure is directed to a radar system. More particularly, the current disclosure relates to a fabrication of aperture-matched array of TEM horn antenna system and use of the same. Specifically, the current disclosure is directed to a compact and lightweight impulse radiating TEM array antenna system with high forward-to-back lobe ratio. Furthermore, the current TEM horn antenna system shows radiation efficiency close to 1 at the frequency bands between 150 and 250 MHz. More particularly, the current disclosure provides transverse electromagnetic (TEM) horn antenna including a curved surface extending arcuately at least 180° degrees from an antenna aperture opening defined at a signal-receiving forward end of a horn structure, wherein the curved surface is adapted to suppress large back-lobe properties. |
| FILED | Friday, December 09, 2016 |
| APPL NO | 15/373562 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 13/02 (20130101) Original (OR) Class H01Q 13/085 (20130101) H01Q 21/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10454517 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jin Zhou (New York, New York); Harish Krishnaswamy (New York, New York) |
| ABSTRACT | Circuits for reducing out-of-band-modulated transmitter self-interference are provided. In some embodiments, receivers are provided, the receivers comprising: a low noise amplifier (LNA) having an input, a first output, and a second output, wherein the LNA includes: a common source transistor having a gate coupled to an input signal, a drain coupled to the first output of the LNA, and a source coupled to ground; and a common gate transistor having a gate coupled to a transmitter replica signal, a source coupled to the gate of the common source transistor, and a drain coupled to the second output of the LNA. |
| FILED | Tuesday, February 10, 2015 |
| APPL NO | 15/117664 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 1/12 (20130101) H04B 1/123 (20130101) H04B 1/525 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10454533 | Kogiantis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vencore Labs, Inc. (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | Vencore Labs, Inc. (Basking Ridge, New Jersey) |
| INVENTOR(S) | Achilles Kogiantis (New York, New York); Kiran Meghashyam Rege (Marlboro, New Jersey); William Harvey Johnson (Rumson, New Jersey); Anthony A. Triolo (Basking Ridge, New Jersey) |
| ABSTRACT | A method of estimating and compensating for Doppler frequency shifts includes providing an accurate reference device for generating an accurate reference frequency in a Doppler estimation and compensation (DEC) system, the DEC system being electrically connected to a user device. The DEC system receives one of a downlink signal from a base station and an uplink signal from the user device. The one of the downlink signal and the uplink signal is compared to the accurate reference frequency. An estimate of a Doppler frequency shift associated with the one of the downlink signal and the uplink signal is determined. An offset Doppler frequency shift of opposite sign as the Doppler frequency shift is added to the one of the downlink signal and uplink signal to provide a compensated signal. The compensated signal is transmitted to one of the base station and user device. |
| FILED | Tuesday, September 18, 2018 |
| APPL NO | 16/134340 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 7/01 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 27/0014 (20130101) H04L 27/266 (20130101) H04L 2027/0026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10454592 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Mo Li (Plymouth, Minnesota); Jian-Ping Wang (Shoreview, Minnesota) |
| ABSTRACT | Techniques are described for data transfer in spin-based systems where digital bit values are represented by magnetization states of magnetoresistive devices rather than voltages or currents. For data transmission, a spin-based signal is converted to an optical signal and transmitted via an optical transport. For data reception, the optical signal is received via the optical transport and converted back to a spin-based signal. Such data transfer may not require an intervening conversion of the spin-based signal to charge-based signal that relies on voltages or currents to represent digital bit values. In addition, techniques are described to use magnetoresistive devices to control the amount of current or voltage that is delivered, where the magnetization state of the magnetoresistive device is set by an optical signal. |
| FILED | Monday, May 07, 2018 |
| APPL NO | 15/972357 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/532 (20130101) H04B 10/671 (20130101) H04B 10/801 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10454759 | Alvarez-Icaza Rivera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Rodrigo Alvarez-Icaza Rivera (San Jose, California); John V. Arthur (Mountain View, California); Andrew S. Cassidy (San Jose, California); Bryan L. Jackson (Fremont, California); Paul A. Merolla (Palo Alto, California); Dharmendra S. Modha (San Jose, California); Jun Sawada (Austin, Texas) |
| ABSTRACT | Embodiments of the invention provide a neurosynaptic network circuit comprising multiple neurosynaptic devices including a plurality of neurosynaptic core circuits for processing one or more data packets. The neurosynaptic devices further include a routing system for routing the data packets between the core circuits. At least one of the neurosynaptic devices is faulty. The routing system is configured for selectively bypassing each faulty neurosynaptic device when processing and routing the data packets. |
| FILED | Tuesday, April 10, 2018 |
| APPL NO | 15/950037 |
| ART UNIT | 2465 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 11/00 (20130101) G06F 11/0724 (20130101) G06F 11/0793 (20130101) Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0659 (20130101) H04L 41/0668 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10454891 | Burnett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Benjamin L. Burnett (Prior Lake, Minnesota); Deborah K. Charan (Minneapolis, Minnesota); Fabio Pozzo (Eden Prairie, Minnesota); Ranga Ramanujan (Medina, Minnesota) |
| ABSTRACT | This disclosure describes a context aware scalable dynamic network whereby network information concerning network elements in an untrusted (Black) network are gathered by network sensors, stored at a network sensor collector, and sent to another network sensor collector in a trusted (Red) network through a one-way guard. At the Red network, the network information from the Black network may be combined with network information from one or more Red networks. The combined network information may then be used to visualize a cross-domain network topology of both Red and Black networks, and to implement network management functions. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/639045 |
| ART UNIT | 2451 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/22 (20130101) H04L 41/28 (20130101) H04L 41/0853 (20130101) H04L 41/0856 (20130101) H04L 63/02 (20130101) Original (OR) Class H04L 63/20 (20130101) H04L 63/0272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10455197 | Giuffrida et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pictometry International Corp. (Rochester, New York) |
| ASSIGNEE(S) | Pictometry International Corp. (Rochester, New York) |
| INVENTOR(S) | Frank D. Giuffrida (Honeoye Falls, New York); Mark A. Winkelbauer (Rochester, New York); Charles Mondello (Pittsford, New York); Robert S. Bradacs (Rochester, New York); Craig D. Woodward (Rochester, New York); Stephen L. Schultz (West Henrietta, New York); Scott D. Lawrence (Pittsford, New York); Matt Kusak (Rochester, New York); Kevin G. Willard (Rochester, New York) |
| ABSTRACT | The present disclosure describes a method for transmitting sensor data and positional data for geo-referencing oblique images from a moving platform to a ground station system in real-time. The method involves the aid of a moving platform system to capture sensor data and positional data for the sensor data, save the sensor data and positional data to one or more directories of one or more computer readable medium, monitor the one or more directories of the one or more computer readable medium for sensor data and positional data, and transmit the sensor data and positional data from the moving platform system to the ground station system over a wireless communication link responsive to the sensor data and positional data being detected as within the one or more directories. |
| FILED | Friday, December 28, 2012 |
| APPL NO | 13/730140 |
| ART UNIT | 2455 — Computer Networks |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 11/02 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/89 (20130101) Image Data Processing or Generation, in General G06T 17/05 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 5/377 (20130101) Transmission H04B 7/18506 (20130101) H04B 7/18508 (20130101) Pictorial Communication, e.g Television H04N 7/005 (20130101) H04N 7/18 (20130101) Original (OR) Class H04N 7/181 (20130101) Wireless Communication Networks H04W 4/027 (20130101) H04W 4/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10455426 | Casey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AMERICAN UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | AMERICAN UNIVERSITY (Washington, District of Columbia) |
| INVENTOR(S) | Stephen D. Casey (Ashburn, Virginia) |
| ABSTRACT | The present embodiments include methods of time-frequency analyzing signals. Some embodiments provide methods of processing signals comprising: adaptively partitioning at least a portion of a signal in a time domain into a plurality of segments of the signal; and transforming each of the segments of the signal producing respective expansions in a frequency domain and obtaining respective samples of the windows of signal in the frequency domain. |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/274450 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Electric Digital Data Processing G06F 17/141 (20130101) Transmission H04B 1/71632 (20130101) Wireless Communication Networks H04W 16/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10448648 | Gruver et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PIONEER HI-BRED INTERNATIONAL, INC. (Johnston, Iowa) |
| ASSIGNEE(S) | PIONEER HI-BRED INTERANTIONAL, INC. (, Iowa) |
| INVENTOR(S) | Steven Gruver (Pacifica, California); Heather Kozy (Walnut Creek, California); Jessica O'Rear (Redwood City, California); Barbara Rosen (Mountain View, California); Ute Schellenberger (Palo Alto, California); Jun-Zhi Wei (Hayward, California); Weiping Xie (East Palo Alto, California); Xiaohong Zhong (San Leandro, California); Genhai Zhu (San Jose, California) |
| ABSTRACT | Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity. |
| FILED | Monday, January 28, 2019 |
| APPL NO | 16/259270 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) A01N 63/02 (20130101) Original (OR) Class Peptides C07K 14/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8286 (20130101) Technologies for Adaptation to Climate Change Y02A 40/162 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449254 | Zakrewsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Triad National Security, LLC (Los Alamos, New Mexico); The Arizona Board of Regents c/o Northern Arizona University (Flagstaff, Arizona) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Triad National Security, LLC (Los Alamos, New Mexico); Arizona Board of Regents c/o Northern Arizona University (Flagstaff, Arizona) |
| INVENTOR(S) | Michael Zakrewsky (Santa Barbara, California); Samir Mitragotri (Santa Barbara, California); David T. Fox (Los Alamos, New Mexico); Andrew Koppisch (Flagstaff, Arizona); Rico Del Sesto (Irvins, Utah); Katherine Lovejoy (Silver Spring, Maryland) |
| ABSTRACT | The compositions and methods described herein are topically applied to the skin with negligible or no skin irritation and can direct or prevent transport through the skin. The compositions contain neat ionic liquids, optionally in combination with a drug to be delivered. In a preferred embodiment, the compositions increase transdermal transport of the drug to be delivered. In some embodiments, the compositions disrupt bacterial biofilms. This is particularly beneficial in the treatment of antibiotic resistant skin infections. In other embodiments, the compositions direct delivery within the skin. In still other embodiments, the compositions prevent transfer of substances through the stratum corneum. The disclosed compositions and methods can be tuned and modified such that they can be used to treat or prevent a variety of different diseases and disorders. |
| FILED | Monday, November 03, 2014 |
| APPL NO | 15/034138 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 33/12 (20130101) A01N 33/12 (20130101) A01N 37/02 (20130101) A01N 37/04 (20130101) A01N 37/06 (20130101) A01N 41/06 (20130101) A01N 41/06 (20130101) A01N 43/36 (20130101) A01N 43/36 (20130101) A01N 47/28 (20130101) A01N 49/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/047 (20130101) A61K 31/66 (20130101) A61K 31/545 (20130101) A61K 47/12 (20130101) A61K 47/24 (20130101) Original (OR) Class A61K 47/186 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449478 | Baxter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sustainable Energy Solutions, LLC (Provo, Utah) |
| ASSIGNEE(S) | Hall Labs LLC (Provo, Utah) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); Kyler Stitt (Lindon, Utah); Christopher Hoeger (Provo, Utah); Aaron Sayre (Spanish Fork, Utah); Eric Mansfield (Spanish Fork, Utah); Nathan Davis (Bountiful, Utah) |
| ABSTRACT | A method for removal of a foulant from a carrier gas is disclosed. A solids conveyance device that spans a vessel and a solids coolant system are provided. A cold solid foulant is provided to the solid inlet of the vessel. The carrier gas containing the foulant is provided to the carrier gas inlet of the vessel. The foulant condenses or desublimates onto the recycled solid foulant, forming a foulant-depleted carrier gas and a solid foulant product. The solids conveyance device passes the solid foulant product out of the vessel. The foulant-depleted carrier gas leaves the vessel. The solid foulant product is split into a final solid foulant product and a recycled solid foulant. The recycled solid foulant is cooled through the coolant system to produce the cold solid foulant. In this manner, the foulant is removed from the carrier gas. |
| FILED | Wednesday, March 29, 2017 |
| APPL NO | 15/472483 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 5/003 (20130101) B01D 8/00 (20130101) B01D 53/002 (20130101) Original (OR) Class B01D 2256/16 (20130101) B01D 2256/20 (20130101) B01D 2256/24 (20130101) B01D 2257/80 (20130101) B01D 2257/302 (20130101) B01D 2257/304 (20130101) B01D 2257/404 (20130101) B01D 2257/408 (20130101) B01D 2257/504 (20130101) B01D 2257/702 (20130101) B01D 2258/0283 (20130101) Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449502 | Rovani, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Wyoming Research Center (Laramie, Wyoming) |
| ASSIGNEE(S) | The University of Wyoming Research Corporateion (Laramie, Wyoming) |
| INVENTOR(S) | Joseph F. Rovani, Jr. (Laramie, Wyoming); Jean-Pascal Planche (Laramie, Wyoming); Ryan Bradley Boysen (Laramie, Wyoming) |
| ABSTRACT | The present invention is generally related to the analysis of chemical compositions of hydrocarbons and hydrocarbon blends. This method, in particular embodiments, may apply specifically to the problem of analyzing extremely complex hydrocarbon-containing mixtures when the number and diversity of molecules makes it extremely difficult or impossible to realistically identify and quantify them individually in a reasonable timeframe. Particular SEC (size exclusion chromatography)-based methods and apparatus disclosed herein may be used to measure, e.g., the molecular size, weight, and/or volume, whether in absolute or relative manner, of the various components of eluate from the SEC stationary phase (e.g., a permeable gel). This analytical method is applicable on a wide variety of hydrocarbonaceous materials, and especially useful for, but not limited to oil, maltenes of oil, asphalt binders and asphalt binder blends, which may contain wide varieties of different types of additives, modifiers, and chemistries. |
| FILED | Wednesday, November 07, 2018 |
| APPL NO | 16/183584 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 17/0014 (20130101) B01F 17/0078 (20130101) B01F 17/0085 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 2395/00 (20130101) Compositions of Macromolecular Compounds C08L 95/005 (20130101) C08L 2555/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/02 (20130101) G01N 33/28 (20130101) Technologies for Adaptation to Climate Change Y02A 30/333 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449632 | Khairallah |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Saad Khairallah (Livermore, California) |
| ABSTRACT | An additive manufacturing system wherein a gentle sintering run on heat-fusible particles is followed closely by a selective laser melting run. The laser sintering run slightly sinters the particles and causes the particles to adhere to each other, but not necessarily deform and lose their original shape. The particles become connected via bridges between each other, which holds them in place. During the laser melting run, the powder melts in place, with minimum particle ejection or mobility, since the particles form a network of connected particles. |
| FILED | Friday, January 18, 2019 |
| APPL NO | 16/252002 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 2003/1056 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/066 (20151001) Original (OR) Class B23K 26/342 (20151001) B23K 26/0622 (20151001) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/20 (20170801) B29C 64/153 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449813 | Kang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Goodyear Tire and Rubber Company (Akron, Ohio) |
| ASSIGNEE(S) | The Goodyear Tire and Rubber Company (Akron, Ohio) |
| INVENTOR(S) | Jungmee Kang (Macedonia, Ohio); Byoung Jo Lee (Copley, Ohio); Daniel Vojtko (Akron, Ohio); Dinesh Chandra (Hudson, Ohio); Betul Buehler (Akron, Ohio); Benjamin Isaiah Garn (Norton, Ohio) |
| ABSTRACT | A self-inflating tire assembly includes an air tube mounted within a tire sidewall or chafer groove. The air tube is in contacting engagement with opposite angled groove surfaces surrounding the air tube. A segment of the air tube is flattened from an expanded diameter to a flat diameter by bending and compression of the groove in a rolling tire footprint to force air evacuated from the flattened segment along a tube air passageway. A coverstrip overlays and seals the groove and provides an abrasion resistant surface on the exterior of the tire. The coverstrip is made from a vulcanizable rubber composition comprising from 50 to 80 phr of a polybutadiene, from 50 to 20 phr of natural rubber, and from 0.1 to 5 phr of a vulcanization modifier. |
| FILED | Thursday, January 26, 2017 |
| APPL NO | 15/416127 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Vehicle Tyres Tyre Inflation; Tyre Changing or Repairing; Repairing, or Connecting Valves To, Inflatable Elastic Bodies in General; Devices or Arrangements Related to Tyres B60C 1/00 (20130101) B60C 13/02 (20130101) B60C 23/12 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 7/00 (20130101) C08L 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10450235 — Method of producing an internal cavity in a ceramic matrix composite and mandrel therefor
| US 10450235 | Gray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Paul Edward Gray (North East, Maryland); Herbert Chidsey Roberts, III (Simpsonville, South Carolina); Glenn Curtis Taxacher (Simpsonville, South Carolina) |
| ABSTRACT | A process for producing an internal cavity in a CMC article and mandrels used therewith. The process entails incorporating a mandrel made of a material that is substantially absorbed during thermal treatment of a preform to form the CMC article. The mandrel material is preferably reactive with one or more constituents of the CMC preform during the thermal treatment. The material is preferably silicon or a silicon alloy. |
| FILED | Thursday, February 28, 2013 |
| APPL NO | 13/780306 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/54 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 22/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/573 (20130101) Original (OR) Class C04B 2235/6026 (20130101) C04B 2235/6028 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) F01D 5/282 (20130101) F01D 5/284 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2300/6033 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/131 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450259 | Gunnoe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Thomas Brent Gunnoe (Palmyra, Virginia); George Fortman (Phoenixville, Pennsylvania); Nicholas C. Boaz (Ewing, New Jersey); John T. Groves (Princeton, New Jersey) |
| ABSTRACT | Embodiments of the present disclosure provide for methods of hydrocarbon functionalization, methods and systems for converting a hydrocarbon into a compound including at least one group ((e.g., hydroxyl group) (e.g., methane to methanol)), functionalized hydrocarbons, and the like. Systems and methods as described herein can utilize photocatalysis. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/119125 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/24 (20130101) B01J 2219/24 (20130101) B01J 2219/00051 (20130101) Acyclic or Carbocyclic Compounds C07C 17/00 (20130101) C07C 19/00 (20130101) C07C 19/03 (20130101) C07C 19/043 (20130101) C07C 29/00 (20130101) C07C 29/03 (20130101) C07C 29/48 (20130101) C07C 29/147 (20130101) C07C 29/147 (20130101) C07C 29/147 (20130101) C07C 29/147 (20130101) C07C 31/04 (20130101) C07C 31/08 (20130101) C07C 31/10 (20130101) C07C 67/035 (20130101) Original (OR) Class C07C 67/035 (20130101) C07C 67/035 (20130101) C07C 69/14 (20130101) C07C 69/14 (20130101) C07C 69/63 (20130101) C07C 69/63 (20130101) C07C 2602/42 (20170501) C07C 2603/74 (20170501) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450336 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Justin Wilson (Los Alamos, New Mexico); Eva Birnbaum (Los Alamos, New Mexico); Kevin John (Santa Fe, New Mexico); Francois Nortier (Los Alamos, New Mexico); Michael Fassbender (Los Alamos, New Mexico); Valery Radchenko (Los Alamos, New Mexico); Jonathan Ward Engle (Los Alamos, New Mexico) |
| ABSTRACT | Selective chelation of bismuth radionuclide ions from a mixture including actinium radionuclide ions involves exposing a ligand to an aqueous solution that includes bismuth radionuclide ions and actinium radionuclide ions under conditions whereby the bismuth radionuclide ions selectively chelate to the ligand for form cationic complexes of the bismuth radionuclide ions. and separating the cationic complexes of the bismuth radionuclide ions from the actinium radionuclide ions. The ligands have a structure based on a 12-membered cyclen ring and may include pendant functional groups that can be derivatized with biological targeting vectors for targeted alpha therapy. |
| FILED | Monday, May 04, 2015 |
| APPL NO | 14/703253 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Heterocyclic Compounds C07D 401/14 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/24 (20130101) C07F 9/94 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450578 | Bartley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Laura E. Bartley (Norman, Oklahoma); Pamela Ronald (Davis, California); Henrik Vibe Scheller (Millbrae, California) |
| ABSTRACT | The invention provides methods of engineering plants to modulate hydroxycinnamic acid content. The invention additionally provides compositions and methods comprising such plants. |
| FILED | Monday, July 17, 2017 |
| APPL NO | 15/652115 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1025 (20130101) C12N 15/8246 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450580 | Ambavaram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yield10 Bioscience, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | Yield10 Bioscience, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Madana M.R. Ambavaram (Norwood, Massachusetts); Mariya Somleva (Cambridge, Massachusetts) |
| ABSTRACT | Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein. |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/897958 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8241 (20130101) C12N 15/8245 (20130101) C12N 15/8251 (20130101) C12N 15/8261 (20130101) Original (OR) Class C12N 15/8271 (20130101) C12N 15/8273 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450641 | Matras et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Maxime R. Matras (Tallahassee, Florida); Eric Hellstrom (Tallahassee, Florida); Ulf Trociewitz (Crawfordsville, Florida); Jianyi Jiang (Tallahassee, Florida); David Larbalestier (Tallahassee, Florida) |
| ABSTRACT | Methods of pre-densifying a metal wire containing superconductor materials are provided. Superconductor materials containing the pre-densified wires also are provided. The wires may be pre-densified by subjecting a metal wire that includes one or more filament cavities in which a superconductor precursor powder is disposed to a temperature and a first pressure for a time sufficient to densify the superconductor precursor powder to form a pre-densified metal wire, wherein the temperature is less than the melting point of the superconductor precursor powder, and the first pressure is sufficient, at the temperature, to compress at least a portion of the metal wire. |
| FILED | Wednesday, July 27, 2016 |
| APPL NO | 15/221042 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450658 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Zhen Li (Shaker Heights, Ohio); Frank Ernst (Cleveland, Ohio); Harold Kahn (Charlottesville, Virginia); Arthur Heuer (Cleveland, Ohio) |
| ABSTRACT | A process for surface activation or depassivation of an article, in particular an alloy, by immersion of the alloy in an aqueous acid solution. The surface activation methods of the present invention can be performed during a relatively short period of time and achieve reductions in production costs and provide environmental friendliness as compared to prior art processes. In a further embodiment, after surface activation, the article is immersed in a second liquid that prevents re-formation of a passivating oxide layer on the surface of the article. In a further embodiment the surface-activated alloys are subjected to surface engineering by a process that infuses carbon or nitrogen through the surface at a temperature sufficiently low to suppress precipitation of carbides or nitrides. |
| FILED | Wednesday, May 06, 2015 |
| APPL NO | 15/308223 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/02 (20130101) C23C 22/02 (20130101) C23C 22/06 (20130101) Original (OR) Class C23C 22/50 (20130101) C23C 22/78 (20130101) Cleaning or Degreasing of Metallic Material by Chemical Methods Other Than Electrolysis C23G 1/02 (20130101) C23G 1/08 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 5/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450660 | Garcia-Diaz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Brenda L. Garcia-Diaz (Aiken, South Carolina); David W. Babineau (Aiken, South Carolina); Hector R. Colon-Mercado (Aiken, South Carolina); Joseph A. Teprovich (Aiken, South Carolina); Luke C. Olson (North Augusta, South Carolina); Roderick E. Fuentes (Aiken, South Carolina) |
| ABSTRACT | Electrochemical cells and methods are described that can be utilized for the recovery of tritium directly from a molten lithium metal solution without the need for a separation or concentration step prior to the electrolytic recovery process. The methods and systems utilize an ion conducting electrolyte that conducts either lithium ion or tritide ion across the electrochemical cell. |
| FILED | Tuesday, November 03, 2015 |
| APPL NO | 14/931018 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 6/04 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/02 (20130101) Original (OR) Class C25B 9/06 (20130101) C25B 9/18 (20130101) C25B 9/142 (20130101) C25B 13/04 (20130101) Fusion Reactors G21B 1/115 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450663 | Rondinone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Adam J. Rondinone (Knoxville, Tennessee); Yang Song (Oak Ridge, Tennessee); Dale K. Hensley (Kingston, Tennessee) |
| ABSTRACT | The invention provides a method of converting nitrogen into ammonia. The method comprises contacting an electrocatalyst with an aqueous solution of dissolved nitrogen gas. The electrocatalyst comprises carbon nanospikes doped with nitrogen. |
| FILED | Tuesday, May 01, 2018 |
| APPL NO | 15/967615 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 11/02 (20130101) C25B 11/04 (20130101) C25B 11/0405 (20130101) C25B 11/0478 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450668 | Korinko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Paul S. Korinko (Aiken, South Carolina); Richard B. Wyrwas (Aiken, South Carolina) |
| ABSTRACT | A multi-step Q-passivation method for stainless steel is described. The method includes a first high voltage electropolishing step followed by as separate low voltage chromium enhancement step. The method can also include a vacuum heat treatment step that utilizes a cyclic ramp-up period so as to maintain a relatively low pressure and low temperature throughout the step. The method can also include a controlled oxidation step during which the surface is contacted with an oxygen/inert gas mixture at low oxygen partial pressure. |
| FILED | Tuesday, April 11, 2017 |
| APPL NO | 15/484210 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450943 | Geyko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vasily Geyko (Hamilton Township, New Jersey); Nathaniel Fisch (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Vasily Geyko (Hamilton Township, New Jersey); Nathaniel Fisch (Princeton, New Jersey) |
| ABSTRACT | An internal combustion engine is disclosed and includes a main cylinder and main piston that are relatively axially displaceable along a main axis to define a variable volume main working chamber. At least one valve is configured to admit air and fuel into the working chamber forming an air/fuel mixture. The main cylinder is configured to cause the air/fuel mixture in the main cylinder to spin rapidly enough to cause a substantive change in the heat capacity of the air/fuel mixture creating a spinning air/fuel mixture. The main cylinder and main piston are configured to compress the spinning air/fuel mixture to create an ignitable spinning air/fuel mixture. The spinning air/fuel mixture is ignited and the main cylinder and main piston are configured to extract mechanical energy from the ignited spinning air/fuel mixture. An exhaust valve is configured to exhaust combustion products from the main working chamber. |
| FILED | Thursday, March 26, 2015 |
| APPL NO | 14/669936 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 31/02 (20130101) Original (OR) Class F02B 31/04 (20130101) F02B 75/28 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/146 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451202 | Baxter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Larry Baxter (Orem, Utah); Nathan Davis (Bountiful, Utah); Aaron Sayre (Spanish Fork, Utah); David Frankman (Provo, Utah); Kyler Stitt (Lindon, Utah); Joe Fox (Spanish Fork, Utah); Skyler Chamberlain (Provo, Utah) |
| ASSIGNEE(S) | Hall Labs LLC (Provo, Utah) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); Nathan Davis (Bountiful, Utah); Aaron Sayre (Spanish Fork, Utah); David Frankman (Provo, Utah); Kyler Stitt (Lindon, Utah); Joe Fox (Spanish Fork, Utah); Skyler Chamberlain (Provo, Utah) |
| ABSTRACT | A device is disclosed comprising a pinchable hose with an inner wall and an outer wall. The hose comprises a flexible material and one or more springs. A central axis of the one or more springs is contained within a space between the inner wall and the outer wall of the hose. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 15/603665 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 7/061 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 11/08 (20130101) F16L 11/12 (20130101) Original (OR) Class F16L 55/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451497 | Polsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Yarom Polsky (Oak Ridge, Tennessee); Michael J. Lance (Oak Ridge, Tennessee); James Gordon Hemrick (Oak Ridge, Tennessee) |
| ABSTRACT | A system and method measuring subterranean stress. The system and method includes a non-destructive sheath enveloping a tubular structure positioned in direct contact with a lateral subterranean rock formation for sensing expansive changes in the subterranean rock formation. A fiber optic is directly embedded in the non-destructive sheath positioned adjacent to the exterior surface of the tubular structure. The fiber optic transmits light and thereafter receives light in proportion to the expansive changes in the subterranean rock formation. A spectrometer connected to the fiber optic remote from the non-destructive sheath. The spectrometer measures hydrostatic stress in the subterranean rock formation without estimating acoustoelastic effects or occluding the tubular structure. |
| FILED | Friday, August 11, 2017 |
| APPL NO | 15/675473 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 33/14 (20130101) E21B 47/0006 (20130101) E21B 49/00 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/242 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451539 | Saha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sourabh Saha (Livermore, California); Robert Matthew Panas (Dublin, California); Michael A. Cullinan (Austin, Texas); Ian Seth Ladner (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Sourabh Saha (Livermore, California); Robert Matthew Panas (Dublin, California); Michael A. Cullinan (Austin, Texas); Ian Seth Ladner (Livermore, California) |
| ABSTRACT | This invention relates to a microelectromechanical device for mechanical characterization of a specimen. In one embodiment the device may incorporate a substrate, at least one first flexure bearing and at least one second flexure bearing, both being supported on the substrate. First and second movable shuttles may be used which are supported above the substrate by the flexure bearings so that each is free to move linearly relative to the substrate. Ends of the movable shuttles are separated by a gap. A thermal actuator may be connected to one end of the first movable shuttle, and operates to cause the first movable shuttle to move in a direction parallel to the surface of the substrate in response to a signal applied to the thermal actuator. A first capacitive sensor may be formed between the first movable shuttle and the substrate, and a second capacitive sensor formed between the second movable shuttle and the substrate. |
| FILED | Friday, March 02, 2018 |
| APPL NO | 15/910604 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/00 (20141201) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/22 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 19/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451580 | McCrory et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Charles McCrory (Ypsilanti, Michigan); Suho Jung (Los Angeles, California); Ryan John-Robert Jones (Pasadena, California) |
| ABSTRACT | A rotating disk electrode cell has a housing with a reservoir configured to receive a sample for an electrochemical experiment. A shaft is positioned in the housing such that the shaft is free to rotate around the longitudinal axis of the shaft and such that both ends of the shaft are located inside of the housing. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/133954 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/125 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/308 (20130101) G01N 27/403 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451745 | Bonal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); National Security Technologies LLC (Las Vegas, Nevada); Decision Sciences International Corporation (Poway, California) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); National Security Technologies LLC (Las Vegas, Nevada); Decision Sciences International Corporation (Poway, California) |
| INVENTOR(S) | Nedra D. Bonal (Albuquerque, New Mexico); Leiph A. Preston (Albuquerque, New Mexico); David Schwellenbach (Los Alamos, New Mexico); Wendi Dreesen (Los Alamos, New Mexico); J. Andrew Green (North Las Vegas, Nevada); Michael Sossong (Ramona, California) |
| ABSTRACT | A muon detector system capable of determining muon direction and flight trajectory or path is disclosed. The muon detector system includes scintillators for determining muon direction, and an array of muon detectors arranged in orthogonal layers for determining flight trajectory. The system can be used for tomographic and telescopic mode imaging, and may be used for imaging concealed and/or subterranean objects. |
| FILED | Thursday, December 10, 2015 |
| APPL NO | 14/965666 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 9/24 (20130101) Measurement of Nuclear or X-radiation G01T 1/2018 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451749 | Rowland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Mark S Rowland (Livermore, California); Neal J Snyderman (Livermore, California) |
| ABSTRACT | A neutron detector system for discriminating fissile material from non-fissile material wherein a digital data acquisition unit collects data at high rate, and in real-time processes large volumes of data directly to count neutrons from the unknown source and detecting excess grouped neutrons to identify fission in the unknown source. The system includes a Poisson neutron generator for in-beam interrogation of a possible fissile neutron source and a DC power supply that exhibits electrical ripple on the order of less than one part per million. Certain voltage multiplier circuits, such as Cockroft-Walton voltage multipliers, are used to enhance the effective of series resistor-inductor circuits components to reduce the ripple associated with traditional AC rectified, high voltage DC power supplies. |
| FILED | Monday, January 30, 2017 |
| APPL NO | 15/419916 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/005 (20130101) Measurement of Nuclear or X-radiation G01T 3/00 (20130101) Original (OR) Class Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451751 | Cao |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Lei Cao (Upper Arlington, Ohio) |
| ABSTRACT | Provided herein are charge generating devices and methods of making and use thereof. The charge generating devices comprise a substrate having a top surface; a plurality of spaced-apart three-dimensional elements disposed on the top surface of the substrate; and a plurality of cavities formed by the plurality of spaced-apart three-dimensional elements, the plurality of cavities being the area between the plurality of spaced-apart three-dimensional elements. The charge generating devices can further comprise a radioactive layer disposed on at least a portion of the plurality of spaced-apart three-dimensional elements and the top surface such that the plurality of cavities and the top surface are substantially coated by the radioactive layer. In some examples, the charge generating devices can comprise a radiation material and/or a scintillating material disposed within at least a portion of the plurality of cavities. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/012186 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/244 (20130101) G01T 3/08 (20130101) Original (OR) Class Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 1/00 (20130101) G21H 1/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/115 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10452437 | Majumdar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Abhinandan Majumdar (Ithaca, New York); Brian J. Kocoloski (Pittsburgh, Pennsylvania); Leonardo Piga (Austin, Texas); Wei Huang (Frisco, Texas); Yasuko Eckert (Redmond, Washington) |
| ABSTRACT | Systems, apparatuses, and methods for performing temperature-aware task scheduling and proactive power management. A SoC includes a plurality of processing units and a task queue storing pending tasks. The SoC calculates a thermal metric for each pending task to predict an amount of heat the pending task will generate. The SoC also determines a thermal gradient for each processing unit to predict a rate at which the processing unit's temperature will change when executing a task. The SoC also monitors a thermal margin of how far each processing unit is from reaching its thermal limit. The SoC minimizes non-uniform heat generation on the SoC by scheduling pending tasks from the task queue to the processing units based on the thermal metrics for the pending tasks, the thermal gradients of each processing unit, and the thermal margin available on each processing unit. |
| FILED | Friday, June 24, 2016 |
| APPL NO | 15/192784 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 1/206 (20130101) G06F 1/329 (20130101) G06F 9/4893 (20130101) Original (OR) Class G06F 9/5094 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/24 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10452548 | Roberts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADVANCED MICRO DEVICES, INC. (Sunnyvale, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | David A. Roberts (Boxborough, Massachusetts); Elliot H. Mednick (Boxborough, Massachusetts) |
| ABSTRACT | A method of preemptive cache writeback includes transmitting, from a first cache controller of a first cache to a second cache controller of a second cache, an unused bandwidth message representing an unused bandwidth between the first cache and the second cache during a first cycle. During a second cycle, a cache line containing dirty data is preemptively written back from the second cache to the first cache based on the unused bandwidth message. Further, the cache line in the second cache is written over in response to a cache miss to the second cache. |
| FILED | Thursday, September 28, 2017 |
| APPL NO | 15/718564 |
| ART UNIT | 2139 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/084 (20130101) G06F 12/126 (20130101) G06F 12/0804 (20130101) G06F 12/0811 (20130101) G06F 12/0831 (20130101) Original (OR) Class G06F 12/0891 (20130101) G06F 2212/60 (20130101) G06F 2212/283 (20130101) G06F 2212/452 (20130101) G06F 2212/507 (20130101) G06F 2212/621 (20130101) G06F 2212/1024 (20130101) G06F 2212/1044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10452717 | Sitik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Ahmet Can Sitik (Hillsboro, Oregon); Ankit More (Hillsboro, Oregon) |
| ABSTRACT | Technologies for node-degree based clustering include a computing device to construct a graph that includes multiple vertices corresponding to the data points of a data set. The computing device inserts an edge between each pair of vertices that has a corresponding similarity metric that meets a predetermined threshold similarity metric. The computing device determines a node degree for each vertex in the graph and initializes a cutoff node degree as the lowest node degree of the vertices. The computing device selects a test subset of the graph that includes vertices having a node degree less than or equal to the cutoff node degree. The computing device determines whether the test subset covers the graph and if not increases the cutoff node degree. If the test subset covers the graph, the data points corresponding to the vertices of the test subset are the representative cluster. Other embodiments are described and claimed. |
| FILED | Thursday, September 22, 2016 |
| APPL NO | 15/272976 |
| ART UNIT | 2167 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9024 (20190101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 5/022 (20130101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453654 | Kobernik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PHOENIX LLC (Monona, Wisconsin) |
| ASSIGNEE(S) | PHOENIX LLC (Monona, Wisconsin) |
| INVENTOR(S) | Arne Kobernik (Monona, Wisconsin); Carl Sherven (Monona, Wisconsin); Casey Lamers (Monona, Wisconsin); Chris Seyfert (Monona, Wisconsin); Evan Sengbusch (Monona, Wisconsin); Gabriel Becerra (Monona, Wisconsin); Jin Lee (Monona, Wisconsin); Logan Campbell (Monona, Wisconsin); Mark Thomas (Monona, Wisconsin); Michael Taylor (Monona, Wisconsin); Preston Barrows (Monona, Wisconsin); Ross Radel (Monona, Wisconsin); Tye Gribb (Monona, Wisconsin) |
| ABSTRACT | Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196697 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/32082 (20130101) Original (OR) Class H01J 41/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453664 | Addleman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Raymond S Addleman (Benton City, Washington); Xiaohong Shari Li (Richland, Washington); Wilaiwan Chouyyok (West Richland, Washington); David A Atkinson (Richland, Washington) |
| ABSTRACT | A unique fiber core sampler composition, related systems, and techniques for designing, making, and using the same are described. The sampler is used to interface with existing field instrumentation, such as Ion Mobility Spectrometer (IMS) equipment. Desired sampler characteristics include its: stiffness/flexibility; thermal mass and conductivity; specific heat; trace substance collection/release dependability, sensitivity and repeatability; thickness; reusability; durability; stability for thermal cleaning; and the like. In one form the sampler has a glass fiber core with a thickness less than 0.3 millimeter that is coated with a polymer including one or more of: polymeric organofluorine, polyimide, polyamide, PolyBenzlmidazole (PBI), PolyDiMethylSiloxane (PDMS), sulfonated tetrafluoroethylene (PFSA) and Poly(2,6-diphenyl-p-phenylene Oxide) (PPPO). Multiple polymer coatings with the same or different polymer types may be included, core/substrate surface functionalization utilized, and/or the core/substrate may be at partially filled with thermally conductive particles. |
| FILED | Tuesday, April 21, 2015 |
| APPL NO | 14/692371 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/002 (20130101) B05D 3/0218 (20130101) B05D 3/0254 (20130101) B05D 5/00 (20130101) B05D 2203/30 (20130101) B05D 2203/35 (20130101) B05D 2505/50 (20130101) B05D 2506/10 (20130101) B05D 2518/10 (20130101) B05D 2518/12 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) G01N 1/405 (20130101) G01N 2001/007 (20130101) G01N 2001/022 (20130101) G01N 2001/024 (20130101) G01N 2001/027 (20130101) G01N 2001/028 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0409 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453988 | Hahn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Carina Hahn (Salt Lake City, Utah); Dennis Pruzan (Salt Lake City, Utah); Michael Scarpulla (Salt Lake City, Utah) |
| ABSTRACT | A method of creating cadmium telluride films is presented. The method demonstrates heterogeneous nucleation of CdTe directly on a substrate through sequential deposition of aqueous precursor solutions containing cadmium and telluride ions, respectively. The method can include (i) applying a cadmium precursor solution to the substrate to form a cadmium precursor film on the substrate, (ii) applying a telluride precursor solution to the cadmium precursor film. The telluride precursor solution includes Te2− in solution such that a CdTe film is adherently formed directly on the substrate. |
| FILED | Monday, June 05, 2017 |
| APPL NO | 15/614391 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/1832 (20130101) H01L 31/1836 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10454124 | Wei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Xiaoliang Wei (Richland, Washington); Wei Wang (Richland, Washington); Aaron M. Hollas (Pasco, Washington); Vincent L. Sprenkle (Richland, Washington); Zimin Nie (Richland, Washington); Bin Li (Richland, Washington) |
| ABSTRACT | Embodiments of an aqueous electrolyte comprising a base and a phenazine derivative are disclosed. Redox flow batteries including the aqueous electrolyte are also disclosed. The phenazine derivative has a chemical structure according to formula I: |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/625750 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 241/46 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/90 (20130101) H01M 4/96 (20130101) H01M 4/9016 (20130101) H01M 8/08 (20130101) H01M 8/188 (20130101) Original (OR) Class H01M 2300/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10454244 | Telford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Steven J. Telford (Livermore, California); Andrew James Bayramian (Manteca, California); Glenn Beer (Manteca, California); Robert J. Deri (Pleasanton, California); Edward S. Fulkerson (Livermore, California); Charles L. Heinbockel (Walnut Creek, California); Edward S. Koh (Livermore, California); Rodney Kay Lanning (Pleasanton, California) |
| ABSTRACT | Apparatuses, methods, and systems are disclosed to drive pumping laser diode arrays. In implementations, an integrated system can be constructed to in a compact, efficient and cost-effective manner and to meet the needs of driving laser diode arrays in various diode pumped solid state laser applications. The disclosed implementations include individual laser diode drivers or pulsers, methods of communicating with laser diode drivers, and methods of controlling the pulse shape of each laser diode driver. |
| FILED | Wednesday, August 09, 2017 |
| APPL NO | 15/673202 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/042 (20130101) Original (OR) Class H01S 5/02469 (20130101) H01S 5/4025 (20130101) H01S 5/06835 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10448989 | Arena et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher B. Arena (Blacksburg, Virginia); Rafael V. Davalos (Blacksburg, Virginia); Michael B. Sano (Blacksburg, Virginia) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Christopher B. Arena (Blacksburg, Virginia); Rafael V. Davalos (Blacksburg, Virginia); Michael B. Sano (Blacksburg, Virginia) |
| ABSTRACT | The present invention relates to the field of biomedical engineering and medical treatment of diseases and disorders. Methods, devices, and systems for in vivo treatment of cell proliferative disorders are provided. In embodiments, the methods comprise the delivery of high-frequency bursts of bipolar pulses to achieve the desired modality of cell death. More specifically, embodiments of the invention relate to a device and method for destroying aberrant cells, including tumor tissues, using high-frequency, bipolar electrical pulses having a burst width on the order of microseconds and duration of single polarity on the microsecond to nanosecond scale. In embodiments, the methods rely on conventional electroporation with adjuvant drugs or irreversible electroporation to cause cell death in treated tumors. The invention can be used to treat solid tumors, such as brain tumors. |
| FILED | Tuesday, December 20, 2011 |
| APPL NO | 13/332133 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) Original (OR) Class A61B 2018/0016 (20130101) A61B 2018/00577 (20130101) A61B 2018/00613 (20130101) A61B 2018/00761 (20130101) A61B 2018/00767 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/327 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449230 | Hamill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kristina Hamill (La Jolla, California); Jeffrey D. Esko (San Diego, California); Lisa McCoy (La Jolla, California); Yitzhak Tor (San Diego, California) |
| ABSTRACT | Provided are transporters based on polymyxin B. Also provided are methods of using the transporters for intracellular delivery of cargo and methods of enhancing intracellular uptake of cargo. |
| FILED | Friday, October 06, 2017 |
| APPL NO | 15/727397 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/12 (20130101) Original (OR) Class A61K 47/62 (20170801) A61K 47/64 (20170801) A61K 47/6911 (20170801) A61K 47/6939 (20170801) Peptides C07K 7/62 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449253 | Miljanic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Ognjen Miljanic (Houston, Texas); Teng-Hao Chen (Houston, Texas); Watchareeya Kaveevivitchai (Houston, Texas) |
| ABSTRACT | A method of delivering or sequestering anesthetic agents by adsorption of such agents by porous partially fluorinated compounds which display high weight adsorption capacities. Such compounds have a non-covalent organic framework with a central ring, such as hexa, tetra, tri or di substituted benzenes which may be substituted or unsubstituted with alternating electron poor and electron rich groups such as tetra-, tri-, or di-fluorobenzenes, oligocyanobenzenes, oligochlorobenzene, and benzene, pirydone, triazole, pyrazole, pyridine, and substituted benzenes so that the compound forms a porous supramolecular structure; and adsorbs the anesthetic agent within the pores of a the compound. |
| FILED | Wednesday, October 03, 2018 |
| APPL NO | 16/150787 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/02 (20130101) A61K 31/08 (20130101) A61K 47/22 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 23/00 (20180101) Separation B01D 53/02 (20130101) B01D 2253/20 (20130101) B01D 2257/2066 (20130101) B01D 2259/4533 (20130101) Heterocyclic Compounds C07D 231/16 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/154 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449267 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy Kuan-Ta Lu (Cambridge, Massachusetts); Chao Zhong (Bedford, Massachusetts) |
| ABSTRACT | Compositions, methods, and kits are provided which involve novel fusion protein-based adhesives for use in medical and marine applications. In some aspects, the novel fusion proteins comprise an adhesive domain (e.g., derived from an adhesive protein of a marine organism) and an amyloid domain (e.g., derived from a bacterial amyloid protein). Also provided are copolymers and fibers of the fusion proteins. |
| FILED | Thursday, November 13, 2014 |
| APPL NO | 14/540872 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/001 (20130101) A61L 24/108 (20130101) Original (OR) Class Peptides C07K 14/78 (20130101) C07K 14/245 (20130101) C07K 14/43504 (20130101) C07K 14/43509 (20130101) C07K 2319/00 (20130101) C07K 2319/70 (20130101) C07K 2319/73 (20130101) C07K 2319/735 (20130101) Derivatives of Natural Macromolecular Compounds C08H 1/00 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 5/00 (20130101) C09J 189/00 (20130101) C09J 2489/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449530 | Nagpal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| INVENTOR(S) | Prashant Nagpal (Lafayette, Colorado); Vivek Singh (Boulder, Colorado); Ignacio Castellanos Beltran (Boulder, Colorado); Yahya Alivov (Boulder, Colorado); Yuchen Ding (Boulder, Colorado); Logan Jerome Cerkovnik (Highlands Ranch, Colorado) |
| ABSTRACT | Photocatalysts for reduction of carbon dioxide and water are provided that can be tuned to produce certain reaction products, including hydrogen, alcohol, aldehyde, and/or hydrocarbon products. These photocatalysts can form artificial photosystems and can be incorporated into devices that reduce carbon dioxide and water for production of various fuels. Doped wide-bandgap semiconductor nanotubes are provided along with synthesis methods. A variety of optical, electronic and magnetic dopants (substitutional and interstitial, energetically shallow and deep) are incorporated into hollow nanotubes, ranging from a few dopants to heavily-doped semiconductors. The resulting wide-bandgap nanotubes, with desired electronic (p- or n-doped), optical (ultraviolet bandgap to infrared absorption in co-doped nanotubes), and magnetic (from paramagnetic to ferromagnetic) properties, can be used in photovoltaics, display technologies, photocatalysis, and spintronic applications. |
| FILED | Thursday, November 30, 2017 |
| APPL NO | 15/827278 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/72 (20130101) B01J 27/04 (20130101) B01J 27/047 (20130101) B01J 27/051 (20130101) B01J 27/0573 (20130101) B01J 35/004 (20130101) Original (OR) Class B01J 35/0013 (20130101) B01J 35/023 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 11/02 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/16 (20130101) C01P 2004/51 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 3/04 (20130101) C25B 11/0478 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/366 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/133 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449579 | Campanella et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts) |
| ABSTRACT | A control system for controlling extraction of landfill gas, the system comprising: at least one sensor; at least one flow control mechanism; and at least one processor configured to perform: obtaining a first measure of energy content in a first portion of landfill gas; controlling the at least one flow control mechanism to increase a flow rate of landfill gas; after the controlling, obtaining a second measure of energy content in a second portion of landfill gas; when it is determined that the second measure of energy content is greater than the first measure of energy content, controlling the at least one flow control mechanism to increase the flow rate of landfill gas; and when it is determined that the second measure of energy content is less than the first measure of energy content, controlling the at least one flow control mechanism to decrease the flow rate of landfill gas. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 15/493184 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450593 | Gonzalez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Ramon Gonzalez (Houston, Texas); James M. Clomburg (Houston, Texas); Jacob E. Vick (Houston, Texas) |
| ABSTRACT | This disclosure describes enzymes from the type II (a discrete set of enzymes) fatty acid synthesis (“FAS”) pathway that can be used in combination with thiolases to operate a functional reversal of the β-oxidation cycle. A combination of thiolases with one or more of 3-oxoacyl-[acyl-carrier-protein] reductase (FabG, others), 3-hydroxyacyl-[acp] dehydratase (FabA, FabZ, others), and enoyl-[acyl-carrier-protein] reductase (FabI, FabK, FabL, FabV, others) yields a functional reversal of the β-oxidation cycle. If only one or two enzymes are used, the remaining enzymes will be traditional beta oxidation enzymes. Once this cycle is coupled with the appropriate priming and termination pathways, the production of carboxylic acids, alcohols, hydrocarbons, amines and their α-, β-, and ω-functionalized derivatives from renewable carbon sources can be achieved. |
| FILED | Monday, January 26, 2015 |
| APPL NO | 15/114502 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) C10L 1/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/00 (20130101) C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0071 (20130101) C12N 9/88 (20130101) C12N 9/1029 (20130101) C12N 9/1096 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/64 (20130101) Original (OR) Class Enzymes C12Y 101/011 (20130101) C12Y 101/03013 (20130101) C12Y 102/01 (20130101) C12Y 102/01003 (20130101) C12Y 103/01009 (20130101) C12Y 114/00 (20130101) C12Y 203/01009 (20130101) C12Y 206/00 (20130101) C12Y 401/99005 (20130101) C12Y 402/01059 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/343 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450599 | Pierce et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Niles A. Pierce (Pasadena, California); Harry Ming Tak Choi (Pasadena, California) |
| ABSTRACT | The present disclosure relates to methods and compositions involving HCR reactions that involve initiators that are split into two or more parts. Effective HCR is dependent upon two or more of these split initiators being brought into proximity (e.g., via binding events mediated by a target) such that a full initiator is formed that is capable of triggering HCR signal amplification. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/639100 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450641 | Matras et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Maxime R. Matras (Tallahassee, Florida); Eric Hellstrom (Tallahassee, Florida); Ulf Trociewitz (Crawfordsville, Florida); Jianyi Jiang (Tallahassee, Florida); David Larbalestier (Tallahassee, Florida) |
| ABSTRACT | Methods of pre-densifying a metal wire containing superconductor materials are provided. Superconductor materials containing the pre-densified wires also are provided. The wires may be pre-densified by subjecting a metal wire that includes one or more filament cavities in which a superconductor precursor powder is disposed to a temperature and a first pressure for a time sufficient to densify the superconductor precursor powder to form a pre-densified metal wire, wherein the temperature is less than the melting point of the superconductor precursor powder, and the first pressure is sufficient, at the temperature, to compress at least a portion of the metal wire. |
| FILED | Wednesday, July 27, 2016 |
| APPL NO | 15/221042 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450652 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Haitao Liu (Pittsburgh, Pennsylvania); Feng Zhou (New York, New York) |
| ABSTRACT | A method of forming a carbonized composition includes providing an organic composition, forming a protective layer over the organic composition, increasing temperature to carbonize the organic composition and for a period of time to form the carbonized composition, and removing the protective layer from the carbonized composition. |
| FILED | Friday, April 14, 2017 |
| APPL NO | 15/487696 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/90 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/04 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/45525 (20130101) Original (OR) Class C23C 18/1283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450750 | Dawood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Mina Dawood (Cypress, Texas); Mossab El-Tahan (Houston, Texas) |
| ABSTRACT | A self-stressing shape memory alloy (SMA)/fiber reinforced polymer (FRP) composite patch is disclosed that can be used to repair cracked steel members or other civil infrastructures. Prestressed carbon FRP (CFRP) patches have emerged as a promising alternative to traditional methods of repair. However, prestressing these patches typically requires heavy and complex fixtures, which is impractical in many applications. This disclosure describes a new approach in which the prestressing force is applied by restraining the shape memory effect of nickel titanium niobium alloy (NiTiNb) SMA wires. The wires are subsequently embedded in an FRP overlay patch. This method overcomes the practical challenges associated with conventional prestressing. |
| FILED | Thursday, January 28, 2016 |
| APPL NO | 15/550297 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 6/04 (20130101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 23/043 (20130101) B28B 23/046 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 73/10 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2305/08 (20130101) B29K 2307/04 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/02 (20130101) B32B 15/08 (20130101) B32B 27/38 (20130101) Alloys C22C 1/00 (20130101) Structural Elements; Building Materials E04C 5/073 (20130101) Original (OR) Class E04C 5/085 (20130101) Scaffolding; Forms; Shuttering; Building Implements or Aids, or Their Use; Handling Building Materials on the Site; Repairing, Breaking-up or Other Work on Existing Buildings E04G 23/0218 (20130101) E04G 2023/0255 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451402 | Yaqoob et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zahid Yaqoob (Cambridge, Massachusetts); Wonshik Choi (Seoul, North Korea); Toyohiko Yamauchi (Hamamatsu, Japan); Michael Feld (, None); David Feld (Newark, California); Alison Hearn (Jamaica Plain, Massachusetts); Jonathan Feld (Somerville, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Hamamatsu Photonics K.K. (Hamamatsu, Japan) |
| INVENTOR(S) | Zahid Yaqoob (Cambridge, Massachusetts); Wonshik Choi (Seoul, North Korea); Toyohiko Yamauchi (Hamamatsu, Japan); Michael Feld (, None) |
| ABSTRACT | The present invention relates to a full-field reflection phase microscope. In a preferred embodiment, the invention can combine low-coherence interferometry and off-axis digital holographic microscopy (DHM). The reflection-based DHM provides highly sensitive and a single-shot imaging of cellular dynamics while the use of low coherence source provides a depth-selective measurement. A preferred embodiment of the system uses a diffraction grating in the reference arm to generate an interference image of uniform contrast over the entire field-of-view albeit low-coherence light source. With improved path-length sensitivity, the present invention is suitable for full-field measurement of membrane dynamics in live cells with sub-nanometer-scale sensitivity. |
| FILED | Wednesday, January 25, 2012 |
| APPL NO | 13/358254 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/04 (20130101) Original (OR) Class G01B 9/0207 (20130101) G01B 9/02032 (20130101) G01B 9/02047 (20130101) G01B 9/02064 (20130101) G01B 9/02084 (20130101) G01B 9/02091 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/45 (20130101) Optical Elements, Systems, or Apparatus G02B 27/50 (20130101) G02B 27/1086 (20130101) Holographic Processes or Apparatus G03H 1/0443 (20130101) G03H 2001/005 (20130101) G03H 2001/0456 (20130101) G03H 2001/0467 (20130101) G03H 2222/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451630 | Salafsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Biodesy, Inc. (South San Francisco, California) |
| ASSIGNEE(S) | BIODESY, INC. (South San Francisco, California) |
| INVENTOR(S) | Joshua Salafsky (San Francisco, California); Louis J. Dietz (Mountain View, California); Ray Hebert (Florence, Oregon); Dar Bahatt (Foster City, California) |
| ABSTRACT | Methods, devices, and systems are disclosed for performing high throughput analysis of conformational change in biological molecules or other biological entities using surface-selective nonlinear optical detection techniques. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 15/965577 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 3/502715 (20130101) B01L 2300/0636 (20130101) B01L 2300/0819 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/552 (20130101) G01N 21/636 (20130101) G01N 33/6845 (20130101) Original (OR) Class G01N 33/54366 (20130101) G01N 33/54373 (20130101) Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 5/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451808 | Bishop et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts); David J. Bishop (Brookline, Massachusetts); Thomas Little (Newtown, Massachusetts); Jessica Morrison (Lynn, Massachusetts); Matthias Imboden (Brookline, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | David J. Bishop (Brookline, Massachusetts); Thomas Little (Newton, Massachusetts); Jessica Morrison (Lynn, Massachusetts); Matthias Imboden (Brookline, Massachusetts) |
| ABSTRACT | The invention provides a device comprising a movable micromirror adapted to receive light from one or more light source(s) and manipulate the reflected light. The micromirror can be actuated electrothermally. In particular, the micromirror is adapted to do at least one of: (a) tipping along a first axis; (b) tilting along a second axis; (c) changing focal length (i.e., varifocal mode); and (d) elevating (i.e., piston mode). The invention also provides a system comprising at least one device comprising a movable micromirror and at least one light source. The invention can be used in smart lighting applications. |
| FILED | Friday, July 22, 2016 |
| APPL NO | 15/747247 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/357 (20130101) G02B 6/3518 (20130101) Original (OR) Class G02B 6/3584 (20130101) G02B 26/02 (20130101) G02B 26/06 (20130101) G02B 26/085 (20130101) G02B 26/0841 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10452143 | Moon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The San Diego University Research Foundation (San Diego, California); Electronics Telecommunications Research Institute (Daejeon, South Korea) |
| ASSIGNEE(S) | San Diego State University Research Foundation (San Diego, California); Electronics and Telecommunication Research Institute (, South Korea) |
| INVENTOR(S) | Kee S. Moon (San Diego, California); Yusuf Ozturk (San Diego, California); Sung Q. Lee (Daejeon, South Korea); Woosub Youm (Daejeon, South Korea); Gunn Hwang (Daejeon, South Korea) |
| ABSTRACT | A device and method is described for electronic human prosthetics, and specifically a skull- and/or spine implantable bi-directional neural-communication/brain-machine interface (BBMI) device where the input, output and on-board computing are combined into a single unit to form a compact neuro-prosthetics device. This invention is also directed to a fully implantable wireless spinal electronic recording and stimulation system using the BBMI in a human. The bi-directional devices (BBMIs) communicate with other bi-directional brain-machine interface devices (BBMI) and/or with external controllers wirelessly. The compact implantable stimulator has ultrasonic secondary battery charging system. One or more BBMI can be wirelessly connected so that a closed loop of BBMIs, or a BBMI and an external controller, can wirelessly send trigger pulses to this fully implanted stimulator over the spinal cord. |
| FILED | Monday, October 17, 2016 |
| APPL NO | 15/295988 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0024 (20130101) A61B 5/0031 (20130101) A61B 5/048 (20130101) A61B 5/0478 (20130101) A61B 5/04001 (20130101) A61B 5/4064 (20130101) A61B 5/4836 (20130101) A61B 2560/0219 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/375 (20130101) A61N 1/0529 (20130101) A61N 1/0551 (20130101) A61N 1/36082 (20130101) A61N 1/36103 (20130101) Electric Digital Data Processing G06F 3/015 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10452451 | Miraftabzadeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Seyed Ali Miraftabzadeh (San Antonoio, Texas); Peyman Najafirad (San Antonio, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Seyed Ali Miraftabzadeh (San Antonoio, Texas); Peyman Najafirad (San Antonio, Texas) |
| ABSTRACT | Disclosed are systems and methods for optimally provisioning tasks to machine instances. The machine instances can correspond to cloud providers and can be part of a multi-cloud. The machine instances can each have various resources available. The task can be received from a user including a job profile. A ranking can be determined for the machine instances. Based on the ranking, the task can be provisioned to one or more of the machine instances. |
| FILED | Monday, June 12, 2017 |
| APPL NO | 15/620345 |
| ART UNIT | 2196 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) Original (OR) Class G06F 9/5083 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0283 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/5019 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10452493 | Yuce et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Virginia Polytechnic Institute and State University (Blacksburg, Virginia) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Bilgiday Yuce (Blacksburg, Virginia); Nahid Farhady Ghalaty (Blacksburg, Virginia); Patrick R. Schaumont (Blacksburg, Virginia) |
| ABSTRACT | Aspects disclosed in the detailed description include a microprocessor fault detection and response system. The microprocessor fault detection and response system utilizes a hardware-based fault-attack aware microprocessor extension (FAME) and a software-based trap handler for detecting and responding to a fault injection on a microprocessor. Upon detecting the fault injection, the hardware FAME switches the microprocessor from a normal mode to a safe mode and instructs the microprocessor to invoke the software-based trap handler in the safe mode. The hardware-based FAME provides fault recovery information to the software-based trap handler via a fault recovery register (FRR) for restoring the microprocessor to a fault-free state. By utilizing a combination of the hardware-based FAME and the software-based trap handler, it is possible to effectively protect the microprocessor from malicious fault attacks without significantly increasing performance and area overheads. |
| FILED | Tuesday, May 16, 2017 |
| APPL NO | 15/596876 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/26 (20130101) G06F 11/1469 (20130101) Original (OR) Class G06F 21/71 (20130101) G06F 21/72 (20130101) G06F 2201/805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10452876 | Ganesan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Deepak Ganesan (Amherst, Massachusetts); Pan Hu (Palo Alto, California); Pengyu Zhang (Palo Alto, California) |
| ABSTRACT | Systems and methods for backscatter communications are provided that employ a backscatter reader to transmit a carrier signal to multiple backscatter tags having heterogeneous hardware and specifications. In response to receiving the carrier, the tags encode data into the received signal and, concurrently, transmit their respective backscattered signal to the reader. The concurrent signals are received by the reader as a combined signal. The reader detects edges in the received signal, based on the corresponding in-phase (I) and quadrature (Q) signals. The edges are then assigned to streams based on the offset or transmission rate of the tags. In some cases, the reader can detect edge collisions. These collisions can be resolved by causing the colliding signals to be retransmitted or by separating the colliding signals. The individual streams corresponding to each of the tags can then be decoded to identify the originally transmitted data from each tag. |
| FILED | Monday, July 31, 2017 |
| APPL NO | 15/664832 |
| ART UNIT | 2683 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10069 (20130101) G06K 7/10158 (20130101) G06K 7/10297 (20130101) Original (OR) Class G06K 19/0709 (20130101) G06K 19/0723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453178 | Isler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Ibrahim Volkan Isler (Minneapolis, Minnesota); Zhengqi Li (Minneapolis, Minnesota) |
| ABSTRACT | A method for generating improved image mosaics includes using a set of overlapping images of a landscape to determine three-dimensional locations for a plurality of features of the landscape. Based on the three-dimensional locations of the plurality of features, a three-dimensional plane of interest is determined. The overlapping images are warped onto the plane of interest to form a mosaic of images. |
| FILED | Wednesday, January 25, 2017 |
| APPL NO | 15/415347 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/123 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 47/08 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00657 (20130101) Image Data Processing or Generation, in General G06T 3/0093 (20130101) G06T 3/4038 (20130101) Original (OR) Class G06T 7/73 (20170101) G06T 7/579 (20170101) G06T 2200/32 (20130101) G06T 2207/10032 (20130101) G06T 2207/20021 (20130101) G06T 2207/20221 (20130101) G06T 2207/30188 (20130101) G06T 2207/30244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453668 | Continetti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Robert Continetti (La Jolla, California); Morgan Miller (La Jolla, California); Brian Adamson (La Jolla, California) |
| ABSTRACT | A spectrometer device for analysis of aerosol particles, dusts, and other microparticles and/or nanoparticles includes an electrospray ionization source supplying a particle stream to an aerodynamic lens that focuses and collimates a beam of particles. An electrostatic trap accepts the beam of particles and traps a single trapped particle at a time in the electrostatic trap to oscillate with a measurable amplitude and frequency. A sensor senses the amplitude and frequency, and a processor determines a calculated mass to charge ratio from the amplitude and frequency of oscillation of the trapped particle in real time. A method creates a focused stream of micro or nanoparticles, traps a single particle at a time in an electrostatic trap. The amplitude and frequency of the oscillation of the trapped particle is sensed. The mass to charge ratio is determined from the amplitude and frequency of oscillation. Particles can be accelerated into a target. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 15/907786 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 2015/0046 (20130101) G01N 2015/1043 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) H01J 49/165 (20130101) H01J 49/4245 (20130101) Original (OR) Class H01J 2237/1207 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 5/06 (20130101) H05H 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453971 | Magaña-Sandoval et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fabian Magaña-Sandoval (Westminster, California); Stefan Ballmer (Syracuse, New York); Thomas Vo (Seattle, Washington); Daniel Vander-Hyde (La Habra, California); Jax Sanders (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | SYRACUSE UNIVERSITY (Syracuse, New York) |
| INVENTOR(S) | Fabian Magaña-Sandoval (Westminster, California); Stefan Ballmer (Syracuse, New York); Thomas Vo (Seattle, Washington); Daniel Vander-Hyde (La Habra, California); Jax Sanders (Milwaukee, Wisconsin) |
| ABSTRACT | A new technique for sensing optical cavity mode mismatch using a mode converter formed from a cylindrical lens mode converting telescope, radio frequency quadrant photodiodes (RFQPDs), and a heterodyne detection scheme. The telescope allows the conversion of the Laguerre-Gauss basis to the Hermite-Gauss (HG) basis, which can be measured with quadrant photodiodes. Conversion to the HG basis is performed optically, measurement of mode mismatched signals is performed with the RFQPDs, and a feedback error signal is obtained with heterodyne detection. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/019889 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 23/2407 (20130101) G02B 27/0955 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0136 (20130101) G02F 2001/0142 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02024 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 27/34 (20130101) H04L 27/223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453996 | Brueck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Steven R. J. Brueck (Albuquerque, New Mexico); Seung-Chang Lee (Albuquerque, New Mexico); Christian Wetzel (Troy, New York); Mark Durniak (Troy, New York) |
| ABSTRACT | A method of forming a semiconductor structure includes providing a substrate comprising a first material portion and a single crystal silicon layer on the first material portion. The substrate further comprises a major front surface, a major backside surface opposing the major front surface, and a plurality of grooves positioned in the major front surface. A buffer layer is deposited in one or more of the plurality of grooves. A semiconductor material is epitaxially grown over the buffer layer and in the one or more plurality of grooves, the epitaxially grown semiconductor material comprising a hexagonal crystalline phase layer and a cubic crystalline phase structure disposed over the hexagonal crystalline phase. |
| FILED | Friday, December 09, 2016 |
| APPL NO | 15/374547 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0243 (20130101) H01L 21/0251 (20130101) H01L 21/0254 (20130101) H01L 21/02381 (20130101) H01L 21/02395 (20130101) H01L 21/02433 (20130101) H01L 21/02458 (20130101) H01L 21/02494 (20130101) H01L 21/02502 (20130101) H01L 21/02587 (20130101) H01L 21/02609 (20130101) H01L 21/7806 (20130101) H01L 29/04 (20130101) H01L 33/04 (20130101) H01L 33/18 (20130101) H01L 33/32 (20130101) Original (OR) Class H01L 33/0075 (20130101) H01L 33/0079 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10455138 | Schillebeeckx et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| ASSIGNEE(S) | Ian Schillebeeckx (San Francisco, California); Robert Pless (Washington, District of Columbia) |
| INVENTOR(S) | Ian Schillebeeckx (St. Louis, Missouri); Robert Pless (St. Louis, Missouri) |
| ABSTRACT | The present disclosure is directed to an approach to solve camera calibration from a single picture of a simply structured light field created by viewing a carefully designed lenticular sheet. The lenticular sheet has different colors visible at different relative orientations and gives linear constraints on the K-1?R matrix which can be decomposed to give the rotation and calibration. The method uses geometric cues from hue measurements and does not require a correspondence between a point in the image and a point on the calibration pattern. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/567746 |
| ART UNIT | 2699 — Search and Capture Special Detail |
| CURRENT CPC | Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 13/36 (20130101) Image Data Processing or Generation, in General G06T 7/80 (20170101) G06T 2200/21 (20130101) G06T 2207/10052 (20130101) Pictorial Communication, e.g Television H04N 5/23212 (20130101) Original (OR) Class H04N 17/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10455219 | Cohen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Adobe Inc. (San Jose, California) |
| ASSIGNEE(S) | Adobe Inc. (San Jose, California) |
| INVENTOR(S) | Scott D. Cohen (Sunnyvale, California); Brian L. Price (San Jose, California); Gowri Somanath (Newark, Delaware) |
| ABSTRACT | Stereo correspondence and depth sensor techniques are described. In one or more implementations, a depth map generated by a depth sensor is leveraged as part of processing of stereo images to assist in identifying which parts of stereo images correspond to each other. The depth map, for instance, may be utilized to assist in identifying depth discontinuities in the stereo images. Additionally, techniques may be employed to align the depth discontinuities identified from the depth map to image edges identified from the stereo images. Techniques may also be employed to suppress image edges that do not correspond to the depth discontinuities of the depth map in comparison with image edges that do correspond to the depth discontinuities as part of the identification. |
| FILED | Friday, November 30, 2012 |
| APPL NO | 13/690724 |
| ART UNIT | 2484 — Recording and Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0346 (20130101) Image Data Processing or Generation, in General G06T 7/593 (20170101) G06T 2207/10012 (20130101) G06T 2207/10028 (20130101) Pictorial Communication, e.g Television H04N 13/122 (20180501) H04N 13/239 (20180501) H04N 13/271 (20180501) Original (OR) Class H04N 2013/0081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10455608 | Shepard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Skylark Wireless, LLC (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clayton Wells Shepard (Houston, Texas); Lin Zhong (Houston, Texas); Abeer Javed (Houston, Texas); Hang Yu (Houston, Texas) |
| ABSTRACT | Disclosed embodiments include methods for control channel design in many-antenna multi-user (MU) multiple-input multiple-output (MIMO) wireless systems. A beacon comprising an identifier of a many-antenna base station is encoded into a base sequence. A plurality of synchronization sequences is generated based on the encoded base sequence and a set of orthogonal beam sequences. The many-antenna base-station transmits, using a plurality of antennas, the plurality of synchronization sequences in a plurality of beam directions associated with the set of orthogonal beam sequences for synchronization and associated with users without knowledge of channel state information (CSI). |
| FILED | Saturday, April 23, 2016 |
| APPL NO | 15/539997 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 7/046 (20130101) H04B 7/0417 (20130101) H04B 7/0452 (20130101) H04B 7/0456 (20130101) H04B 7/0617 (20130101) H04B 7/0695 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0053 (20130101) H04L 27/2613 (20130101) H04L 27/2692 (20130101) Wireless Communication Networks H04W 48/00 (20130101) H04W 56/001 (20130101) H04W 68/02 (20130101) H04W 72/14 (20130101) Original (OR) Class H04W 72/0446 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10449672 | Assad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Christopher Assad (Monrovia, California); Jaakko T. Karras (Pasadena, California); Michael T. Wolf (La Crescenta, California); Adrian Stoica (Pasadena, California) |
| ABSTRACT | A sleeve worn on an arm allows detection of gestures by an array of sensors. Electromyography, inertial, and magnetic field sensors provide data that is processed to categorize gestures and translate the gestures into commands for robotic systems. Machine learning allows training of gestures to increase accuracy of detection for different users. |
| FILED | Tuesday, February 28, 2017 |
| APPL NO | 15/445693 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/486 (20130101) A61B 5/0492 (20130101) A61B 5/1122 (20130101) A61B 5/04888 (20130101) A61B 5/6806 (20130101) A61B 5/6824 (20130101) A61B 5/7267 (20130101) A61B 34/74 (20160201) A61B 2017/00039 (20130101) A61B 2017/00207 (20130101) A61B 2034/741 (20160201) A61B 2560/0223 (20130101) A61B 2562/0219 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/163 (20130101) Original (OR) Class B25J 13/02 (20130101) B25J 13/087 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/409 (20130101) G05B 2219/35448 (20130101) G05B 2219/35464 (20130101) G05B 2219/36418 (20130101) G05B 2219/40195 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449804 | Padula, II et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Santo A. Padula, II (Valley City, Ohio); James Benzing (Cleveland, Ohio); Vivake M. Asnani (North Olmsted, Ohio) |
| ABSTRACT | A tire includes a plurality of SMA springs. Each SMA spring includes a first end portion, a second end portion, and an arching middle portion. Each SMA spring is interlaced with at least one other SMA spring thereby forming a laced toroidal structure extending about an entire circumference of the tire. |
| FILED | Tuesday, December 06, 2016 |
| APPL NO | 15/370322 |
| ART UNIT | 3617 — Printing/Measuring and Testing |
| CURRENT CPC | Vehicle Tyres Tyre Inflation; Tyre Changing or Repairing; Repairing, or Connecting Valves To, Inflatable Elastic Bodies in General; Devices or Arrangements Related to Tyres B60C 7/06 (20130101) B60C 7/20 (20130101) Original (OR) Class Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology B60Y 2200/80 (20130101) Alloys C22C 5/02 (20130101) C22C 5/04 (20130101) C22C 9/05 (20130101) C22C 13/00 (20130101) C22C 18/02 (20130101) C22C 19/03 (20130101) C22C 20/00 (20130101) C22C 27/02 (20130101) C22C 30/00 (20130101) C22C 30/02 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450080 | Beach |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S.A., as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Raymond F. Beach (North Olmsted, Ohio) |
| ABSTRACT | A hybrid propulsion system for an aircraft is provided that includes a turbine engine, a first electric machine assembly connected to the turbine engine, a second electric machine assembly driven by the first electric machine assembly, and multiple third electric machine assemblies driven by the first electric machine assembly, wherein the multiple third electric machines provide a thrust output to propel the aircraft. |
| FILED | Monday, March 28, 2016 |
| APPL NO | 15/082350 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/10 (20130101) B64D 27/24 (20130101) Original (OR) Class B64D 2027/026 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 903/96 (20130101) Y10S 903/906 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450432 | Gordon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Keith L. Gordon (Hampton, Virginia); Emilie J. Siochi (Newport News, Virginia); Brian W. Grimsley (Williamsburg, Virginia); Roberto J. Cano (Yorktown, Virginia); Michael W. Czabaj (Salt Lake City, Utah) |
| ABSTRACT | A composite comprising a combination of a self-healing polymer matrix and a carbon fiber reinforcement is described. In one embodiment, the matrix is a polybutadiene graft copolymer matrix, such as polybutadiene graft copolymer comprising poly(butadiene)-graft-poly(methyl acrylate-co-acrylonitrile). A method of fabricating the composite is also described, comprising the steps of manufacturing a pre-impregnated unidirectional carbon fiber preform by wetting a plurality of carbon fibers with a solution, the solution comprising a self-healing polymer and a solvent, and curing the preform. A method of repairing a structure made from the composite of the invention is described. A novel prepreg material used to manufacture the composite of the invention is described. |
| FILED | Tuesday, October 10, 2017 |
| APPL NO | 15/729189 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/28 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/24 (20130101) Original (OR) Class C08J 5/042 (20130101) C08J 2351/04 (20130101) C08J 2351/06 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450650 | Sultana et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S.A. represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Admininstrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Mahmooda Sultana (Laurel, Maryland); Mary J. Li (Bethesda, Maryland); Anthony W. Yu (Spencerville, Maryland) |
| ABSTRACT | The present invention relates to a method of manufacturing large area graphene for graphene-based photonics devices such as bolometric graphene detectors, or for use as a saturable absorber in ultra-high bandwidth detectors for producing ultrafast laser pulses. The method includes: growing a first graphene layer on one side of a metal substrate, and a second graphene layer on another side of the metal substrate; coating the first graphene layer with a plurality of resist layers including a low molecular weight polymethylmethacrylate, and a high molecular weight polymethylmethacrylate; removing the second graphene layer and the metal substrate to reveal the first graphene layer; disposing the first graphene layer on an optical substrate; and removing the plurality of resist layers from the first graphene layer to reveal a final graphene layer, which can be used as the basis to manufacture a multilayer graphene structure for graphene detectors. |
| FILED | Thursday, September 24, 2015 |
| APPL NO | 14/864442 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/186 (20170801) C01B 32/194 (20170801) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/01 (20130101) C23C 16/26 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/02 (20130101) G02B 6/0008 (20130101) G02B 6/3624 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/011 (20130101) G02F 1/3523 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451156 | Krasowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Adminstration (Washington, District of Columbia) |
| INVENTOR(S) | Michael J. Krasowski (Chagrin Falls, Ohio); Lawrence C. Greer (Avon, Ohio) |
| ABSTRACT | A robust ground traction (drive) assembly for remotely controlled vehicles, which not only operates smoothly on surfaces that are flat, but also upon surfaces that include rugged terrain, snow, mud, and sand, is provided. The assembly includes a sun gear and a braking gear. The sun gear is configured to cause rotational force to be applied to second planetary gears through a coupling of first planetary gears. The braking gear is configured to cause the assembly (or the second planetary gears) to rotate around the braking gear when an obstacle or braking force is applied. |
| FILED | Friday, May 26, 2017 |
| APPL NO | 15/606613 |
| ART UNIT | 3655 — Material and Article Handling |
| CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/06 (20130101) A61G 5/061 (20130101) A61G 5/065 (20130101) Gearing F16H 1/36 (20130101) F16H 3/58 (20130101) F16H 3/663 (20130101) F16H 37/041 (20130101) Original (OR) Class F16H 2001/2881 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451347 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | John C. Gray (Merritt Island, Florida); Daniel F. Reynolds (Houston, Texas) |
| ABSTRACT | A condensation-controlling insulation system includes an interior insulation layer for application to a cold surface. The system may further include an exterior absorption layer adapted to retain condensation during a first environmental condition and to release the condensation as a vapor during a second environmental condition. |
| FILED | Wednesday, June 22, 2016 |
| APPL NO | 15/189613 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/40 (20130101) B64C 1/067 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/58 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/029 (20130101) Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 5/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451570 | Mandrake et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Lukas Mandrake (Altadena, California); Martin W. Lo (Altadena, California) |
| ABSTRACT | Backscatter imaging systems and methods that involve moving an emitter and a broad spectrum detector in helical motion along a medium being imaged while the emitter emits substantially monochromatic X-rays and/or gamma rays, and the broad spectrum detector acquires intensity measurement of photons backscattered from the medium. The intensity measurements are transformed into three-dimensional image data of the medium corresponding to density variations. |
| FILED | Tuesday, May 02, 2017 |
| APPL NO | 15/585026 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/203 (20130101) Original (OR) Class G01N 2223/053 (20130101) G01N 2223/315 (20130101) G01N 2223/1003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453621 | Rolin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (, None) |
| INVENTOR(S) | Terry D. Rolin (Elkmont, Alabama); Curtis W. Hill (Meridianville, Alabama) |
| ABSTRACT | An ink of the formula: 60-80% by weight BaTiO3 particles coated with SiO2; 5-50% by weight high dielectric constant glass; 0.1-5% by weight surfactant; 5-25% by weight solvent; and 5-25% weight organic vehicle. Also a dielectric made by: heating particles of BaTiO3 for a special heating cycle, under a mixture of 70-96% by volume N2 and 4-30% by volume H2 gas; depositing a film of SiO2 over the particles; mechanically separating the particles; forming them into a layer; and heating at 850-900° C. for less than 5 minutes and allowing the layer to cool to ambient temperature in N2 atmosphere. |
| FILED | Tuesday, December 12, 2017 |
| APPL NO | 15/839418 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 8/20 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/64 (20130101) C04B 35/632 (20130101) C04B 35/638 (20130101) C04B 35/4682 (20130101) C04B 35/6262 (20130101) C04B 35/6264 (20130101) C04B 35/6265 (20130101) C04B 35/6268 (20130101) C04B 35/6303 (20130101) C04B 35/6316 (20130101) C04B 35/62222 (20130101) C04B 35/62807 (20130101) C04B 35/62813 (20130101) C04B 35/62884 (20130101) C04B 35/62897 (20130101) C04B 2235/36 (20130101) C04B 2235/96 (20130101) C04B 2235/365 (20130101) C04B 2235/768 (20130101) C04B 2235/3215 (20130101) C04B 2235/3217 (20130101) C04B 2235/3236 (20130101) C04B 2235/3418 (20130101) C04B 2235/5445 (20130101) C04B 2235/6026 (20130101) C04B 2235/6562 (20130101) C04B 2235/6567 (20130101) C04B 2235/6584 (20130101) C04B 2235/6586 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/1227 (20130101) H01G 11/56 (20130101) H01G 11/84 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10449579 | Campanella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts) |
| ABSTRACT | A control system for controlling extraction of landfill gas, the system comprising: at least one sensor; at least one flow control mechanism; and at least one processor configured to perform: obtaining a first measure of energy content in a first portion of landfill gas; controlling the at least one flow control mechanism to increase a flow rate of landfill gas; after the controlling, obtaining a second measure of energy content in a second portion of landfill gas; when it is determined that the second measure of energy content is greater than the first measure of energy content, controlling the at least one flow control mechanism to increase the flow rate of landfill gas; and when it is determined that the second measure of energy content is less than the first measure of energy content, controlling the at least one flow control mechanism to decrease the flow rate of landfill gas. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 15/493184 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451883 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Magic Leap, Inc. (Plantation, Florida) |
| ASSIGNEE(S) | Magic Leap, Inc. (Plantation, Florida) |
| INVENTOR(S) | Chunyu Gao (Tucson, Arizona); Yuxiang Lin (Tucson, Arizona); Hong Hua (Tucson, Arizona) |
| ABSTRACT | The present invention comprises a compact optical see-through head-mounted display capable of combining, a see-through image path with a virtual image path such that the opaqueness of the see-through image path can be modulated and the virtual image occludes parts of the see-through image and vice versa. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196886 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 13/06 (20130101) G02B 25/001 (20130101) G02B 27/144 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 27/283 (20130101) G02B 27/1066 (20130101) G02B 2027/015 (20130101) G02B 2027/0118 (20130101) G02B 2027/0145 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 37/02 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Pictorial Communication, e.g Television H04N 5/2258 (20130101) H04N 5/23238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453775 | Carlson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SA Photonics, Inc. (Los Gatos, California) |
| ASSIGNEE(S) | SA Photonics, Inc. (Los Gatos, California) |
| INVENTOR(S) | Mark Carlson (Campbell, California) |
| ABSTRACT | A thermoelectric module for cooling a heat source includes multiple major sections, each major section including multiple minor sections. Each minor section includes one or more thermoelectric cooler (TEC) units including P-type and N-type semiconductors. Each major section also includes a single output terminal commonly connected to the minor sections, where the output terminal is configured to provide a same reference voltage signal to each of the minor sections. Each major section also comprises multiple input terminals, where each input terminal is separately connected to one of the minor sections and each input terminal is configured to provide a separate input voltage signal to each of the minor sections. The module also comprises a controller configured to independently control each reference voltage signal applied to each major section, and independently control each input voltage signal applied to each input terminal of each minor section within each major section. |
| FILED | Wednesday, June 10, 2015 |
| APPL NO | 14/736202 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/38 (20130101) Original (OR) Class H01L 35/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10453984 | Yao |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WAVEFRONT HOLDINGS, LLC (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | WAVEFRONT HOLDINGS, LLC (Basking Ridge, New Jersey) |
| INVENTOR(S) | Jie Yao (Plainsboro, New Jersey) |
| ABSTRACT | Disclosed are phototransistors, and more specifically a detector that includes two or more phototransistors, conductively isolated from each other. Embodiments also relate to methods of making the detector. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/467478 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/146 (20130101) H01L 27/1463 (20130101) H01L 27/14603 (20130101) H01L 27/14609 (20130101) H01L 27/14694 (20130101) H01L 31/1105 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10455197 | Giuffrida et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pictometry International Corp. (Rochester, New York) |
| ASSIGNEE(S) | Pictometry International Corp. (Rochester, New York) |
| INVENTOR(S) | Frank D. Giuffrida (Honeoye Falls, New York); Mark A. Winkelbauer (Rochester, New York); Charles Mondello (Pittsford, New York); Robert S. Bradacs (Rochester, New York); Craig D. Woodward (Rochester, New York); Stephen L. Schultz (West Henrietta, New York); Scott D. Lawrence (Pittsford, New York); Matt Kusak (Rochester, New York); Kevin G. Willard (Rochester, New York) |
| ABSTRACT | The present disclosure describes a method for transmitting sensor data and positional data for geo-referencing oblique images from a moving platform to a ground station system in real-time. The method involves the aid of a moving platform system to capture sensor data and positional data for the sensor data, save the sensor data and positional data to one or more directories of one or more computer readable medium, monitor the one or more directories of the one or more computer readable medium for sensor data and positional data, and transmit the sensor data and positional data from the moving platform system to the ground station system over a wireless communication link responsive to the sensor data and positional data being detected as within the one or more directories. |
| FILED | Friday, December 28, 2012 |
| APPL NO | 13/730140 |
| ART UNIT | 2455 — Computer Networks |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 11/02 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/89 (20130101) Image Data Processing or Generation, in General G06T 17/05 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 5/377 (20130101) Transmission H04B 7/18506 (20130101) H04B 7/18508 (20130101) Pictorial Communication, e.g Television H04N 7/005 (20130101) H04N 7/18 (20130101) Original (OR) Class H04N 7/181 (20130101) Wireless Communication Networks H04W 4/027 (20130101) H04W 4/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10448578 | Lyons et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | David Lyons (Lafayette, Louisiana); Paul Heinemann (University Park, Pennsylvania) |
| ABSTRACT | The invention relates to an end-effector device and automated selective thinning system. The system includes vision acquisition hardware, kinematic targeting and heuristic programming, a robotic arm, and a pomologically designed end-effector. The system is utilized to improve efficiency for the fruit-thinning process in a tree orchard, such as peach thinning By automating the mechanical process of fruit thinning, selective fruit-thinners can eliminate manual labor inputs and further enhance favorable blossom removal. Automation used in conjunction with a heuristic approach provides improvements to the system. The system may also be configured as a robotic arm or as a handheld system by including a battery and switching microcontroller with handle or wrist straps. Handheld thinning devices that are mechanical in nature may also be part of the system. |
| FILED | Tuesday, July 21, 2015 |
| APPL NO | 14/804933 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Soil Working in Agriculture or Forestry; Parts, Details, or Accessories of Agricultural Machines or Implements, in General A01B 41/06 (20130101) Harvesting; Mowing A01D 46/30 (20130101) Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 3/02 (20130101) Original (OR) Class A01G 3/037 (20130101) A01G 2003/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450364 | Lillehoj et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); Arkion Life Sciences, LLC (New Castle, Delaware) |
| ASSIGNEE(S) | Arkion Life Sciences, LLC (New Castle, Delaware); United Sates of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Hyun S. Lillehoj (West Friendship, Maryland); Earnest W. Porta (Landenberg, Pennsylvania); Samuel V. Walker (Elkton, Maryland); Leslie A. Confer (West Chester, Pennsylvania); Ujvala Deepthi Gadde (Ashburn, Virginia); Cyril Gay (Bethesda, Maryland) |
| ABSTRACT | In one aspect, the present invention is directed to a method for preventing or treating necrotic enteritis by administering a hyperimmunized egg product obtained from an egg-producing animal to an avian. The hyperimmunized egg product may contain an antibody specific to an antigen selected from the group consisting of Clostridium perfringens α-toxin, Clostridium perfringens elongation factor Tu (EF-Tu), Clostridium perfringens necrotic enteritis B-like (NetB) toxin, Clostridium perfringens Pyruvate: Ferredoxin oxidoreductase (PFO), and Eimeria tenella elongation factor 1-alpha. |
| FILED | Tuesday, February 13, 2018 |
| APPL NO | 15/895636 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Fodder A23K 10/18 (20160501) A23K 10/20 (20160501) A23K 50/75 (20160501) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0056 (20130101) A61K 47/46 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) A61P 31/04 (20180101) Peptides C07K 16/02 (20130101) Original (OR) Class C07K 16/20 (20130101) C07K 16/1282 (20130101) C07K 2317/11 (20130101) C07K 2319/23 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10451556 | Robinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Joseph Paul Robinson (West Lafayette, Indiana); Bartlomiej P. Rajwa (West Lafayette, Indiana); Valery P. Patsekin (West Lafayette, Indiana); Euiwon Bae (West Lafayette, Indiana) |
| ABSTRACT | An apparatus and method for characterizing a target, e.g., microbial samples or biological toxins, includes labeling the target with a biomolecular recognition construct and measuring an atomic-spectra signal of the biomolecular recognition construct. The method can include heating the labeled target before measuring the atomic-spectra signal. The atomic-spectra signal can be measured by performing laser-induced breakdown spectroscopy. The atomic-spectra signal can be measured by performing spark induced breakdown spectroscopy. The biomolecular recognition construct can be prepared by tagging a biological scaffolding with a metal atom or ion. In an aspect in which the target includes a microbial sample, the biological scaffolding can include an antibody against epitopes present on bacterial surface, the antibody linked to a heavy metal. In an aspect in which the target includes a biological toxin, the biological scaffolding can include an antibody against the biological toxin linked to heavy metals. |
| FILED | Monday, September 14, 2015 |
| APPL NO | 15/510319 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/25 (20130101) G01N 21/67 (20130101) G01N 21/718 (20130101) Original (OR) Class G01N 33/58 (20130101) G01N 33/569 (20130101) G01N 33/56911 (20130101) G01N 2469/00 (20130101) G01N 2469/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10448877 | Truccolo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wilson Truccolo (Providence, Rhode Island); Leigh R. Hochberg (Brookline, Massachusetts); John P. Donoghue (Providence, Rhode Island); Sydney S. Cash (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island); The General Hospital Corporation (Boston, Massachusetts); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Wilson Truccolo (Providence, Rhode Island); Leigh R. Hochberg (Brookline, Massachusetts); John P. Donoghue (Providence, Rhode Island); Sydney S. Cash (Cambridge, Massachusetts) |
| ABSTRACT | Several methods for prediction and detection of neurological events are proposed based on spatiotemporal patterns in recorded neural signals. The methods are illustrated with examples from neural data recorded from human and non-human primates. |
| FILED | Monday, December 05, 2011 |
| APPL NO | 13/991680 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/048 (20130101) A61B 5/0476 (20130101) A61B 5/0482 (20130101) A61B 5/04012 (20130101) A61B 5/4094 (20130101) Original (OR) Class A61B 5/7282 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10449269 | Fahmy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Tarek M. Fahmy (New Haven, Connecticut); Alan Dardik (Bethany, Connecticut) |
| ABSTRACT | Composite prosthetic patches with covalently bound particles for controlled drug release, and methods of making and using thereof, have been developed. The particles may encapsulate one or more therapeutic, prophylactic or diagnostic agent(s). Generally, the prosthetic patches are decellularized extracellular matrix such as bovine or porcine pericardium or synthetic polymeric materials. The size of the particles ranges from between 1 nm and 1000 μm, preferably from between 10 nm and 500 nm. In some embodiments, the agent is a therapeutic agent for treatment of neointimal hyperplasia. In other embodiments, the agent is a therapeutic agent for suppressing or resolving inflammation. In yet other embodiments, the agent is a therapeutic for mitigating scarring. |
| FILED | Monday, August 28, 2017 |
| APPL NO | 15/687738 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/4439 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/26 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 27/306 (20130101) A61L 27/3604 (20130101) A61L 27/3633 (20130101) A61L 27/3641 (20130101) Original (OR) Class A61L 27/3687 (20130101) A61L 2300/62 (20130101) A61L 2400/12 (20130101) A61L 2400/18 (20130101) A61L 2420/06 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10450371 | Clauss et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Matthias Clauss (Indianapolis, Indiana); Irina Petrache (Indianapolis, Indiana); Robert Voswinckel (Geissen, Germany) |
| ABSTRACT | The present invention provides methods for diagnosing a patient with emphysema, COPD of lung injury caused by tobacco use by detecting the levels of EMAP II in a sample. Disclosed herein are the hypervariable regions for a rat monoclonal antibody that binds to a form of EMAP II. This disclosure also includes a polypeptide sequence included in EMAP II that is the target for the binding of the antibody to its target protein. This epitope serves as the basis for a humanized antibody that can be used to treat patients that suffer from pathologies that exhibit elevated levels of EMAP II expression. |
| FILED | Wednesday, October 18, 2017 |
| APPL NO | 15/787237 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) C07K 16/22 (20130101) Original (OR) Class C07K 16/2866 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10455197 | Giuffrida et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pictometry International Corp. (Rochester, New York) |
| ASSIGNEE(S) | Pictometry International Corp. (Rochester, New York) |
| INVENTOR(S) | Frank D. Giuffrida (Honeoye Falls, New York); Mark A. Winkelbauer (Rochester, New York); Charles Mondello (Pittsford, New York); Robert S. Bradacs (Rochester, New York); Craig D. Woodward (Rochester, New York); Stephen L. Schultz (West Henrietta, New York); Scott D. Lawrence (Pittsford, New York); Matt Kusak (Rochester, New York); Kevin G. Willard (Rochester, New York) |
| ABSTRACT | The present disclosure describes a method for transmitting sensor data and positional data for geo-referencing oblique images from a moving platform to a ground station system in real-time. The method involves the aid of a moving platform system to capture sensor data and positional data for the sensor data, save the sensor data and positional data to one or more directories of one or more computer readable medium, monitor the one or more directories of the one or more computer readable medium for sensor data and positional data, and transmit the sensor data and positional data from the moving platform system to the ground station system over a wireless communication link responsive to the sensor data and positional data being detected as within the one or more directories. |
| FILED | Friday, December 28, 2012 |
| APPL NO | 13/730140 |
| ART UNIT | 2455 — Computer Networks |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 11/02 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/89 (20130101) Image Data Processing or Generation, in General G06T 17/05 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 5/377 (20130101) Transmission H04B 7/18506 (20130101) H04B 7/18508 (20130101) Pictorial Communication, e.g Television H04N 7/005 (20130101) H04N 7/18 (20130101) Original (OR) Class H04N 7/181 (20130101) Wireless Communication Networks H04W 4/027 (20130101) H04W 4/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 10451378 | Vabnick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Federal Bureau of Investigation (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE FEDERAL BUREAU OF INVESTIGATION, DEPARTMENT OF JUSTICE (Washington, District of Columbia) |
| INVENTOR(S) | Ian B. Vabnick (Quantico, Virginia); Thomas A. Sharkey (Quantico, Virginia); Joseph Santiso (Quantico, Virginia) |
| ABSTRACT | Provided herein are fluid jet enhancement adapters for use with a propellant driven disrupter. The adapter may comprise: a first end operably connected to a muzzle end of a propellant driven disrupter barrel and a second end, wherein a longitudinal region extends between the first end and the second end. The longitudinal region has: a longitudinal region inner surface that defines a longitudinal region lumen; a longitudinal region outer surface opposably facing the longitudinal region inner surface, with a longitudinal region wall having a wall thickness that separates the longitudinal region inner surface from the longitudinal region outer surface. The longitudinal region lumen has a first end inner diameter that is substantially equivalent to a muzzle inner diameter. The longitudinal region wall forms a continuous surface that radially isolates the longitudinal region lumen from a surrounding environment. |
| FILED | Wednesday, February 14, 2018 |
| APPL NO | 15/896760 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Weapons for Projecting Missiles Without Use of Explosive or Combustible Propellant Charge; Weapons Not Otherwise Provided for F41B 9/0046 (20130101) F41B 9/0075 (20130101) Original (OR) Class Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 33/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 10454533 | Kogiantis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vencore Labs, Inc. (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | Vencore Labs, Inc. (Basking Ridge, New Jersey) |
| INVENTOR(S) | Achilles Kogiantis (New York, New York); Kiran Meghashyam Rege (Marlboro, New Jersey); William Harvey Johnson (Rumson, New Jersey); Anthony A. Triolo (Basking Ridge, New Jersey) |
| ABSTRACT | A method of estimating and compensating for Doppler frequency shifts includes providing an accurate reference device for generating an accurate reference frequency in a Doppler estimation and compensation (DEC) system, the DEC system being electrically connected to a user device. The DEC system receives one of a downlink signal from a base station and an uplink signal from the user device. The one of the downlink signal and the uplink signal is compared to the accurate reference frequency. An estimate of a Doppler frequency shift associated with the one of the downlink signal and the uplink signal is determined. An offset Doppler frequency shift of opposite sign as the Doppler frequency shift is added to the one of the downlink signal and uplink signal to provide a compensated signal. The compensated signal is transmitted to one of the base station and user device. |
| FILED | Tuesday, September 18, 2018 |
| APPL NO | 16/134340 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 7/01 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 27/0014 (20130101) H04L 27/266 (20130101) H04L 2027/0026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 10452729 | Keegan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Matthew S. Keegan (Santa Monica, California); Ryan F. Compton (Los Angeles, California); Tsai-Ching Lu (Thousand Oaks, California) |
| ABSTRACT | Described is a system for event prediction on microblogs. In operation, the system receives a social media post stream from a social network to generate and maintain a social network database and an audit trail database. New social media posts are filtered to determine if the new social media posts are related to a possible future event. The new social media posts are compared against the social network database and audit trail database to provide a quality score, the quality score representing a likelihood that at least one of the new social media posts is a true prediction of a future event. If the quality score is determined to be true, the detection is published as a true prediction of a future event. |
| FILED | Wednesday, August 19, 2015 |
| APPL NO | 14/830289 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/958 (20190101) G06F 16/9535 (20190101) Original (OR) Class G06F 16/24578 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10449763 | Abbott, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (Houston, Texas); The State of Oregon State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (Spring, Texas); Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | James Elmer Abbott, Jr. (Corvallis, Oregon); John M McGlone (Corvallis, Oregon); Kristopher Olsen (Corvallis, Oregon); Roberto A Pugliese (Tangent, Oregon); Greg Scott Long (Corvallis, Oregon); Douglas A Keszler (Corvallis, Oregon); John Wager (Corvallis, Oregon) |
| ABSTRACT | An amorphous thin metal film can include a combination of metals or metalloids including: 5 at % to 74 at % of a metalloid selected from the group of carbon, silicon, and boron; 5 at % to 74 at % of a first metal; 5 at % to 74 at % of a second metal; and 5 at % to 70 at % of a dopant. The first and second metals can be independently selected from the group of titanium, vanadium, chromium, iron, cobalt, nickel, zirconium, niobium, molybdenum, ruthenium, rhodium, palladium, hafnium, tantalum, tungsten, osmium, iridium, or platinum, wherein the first metal and the second metal can be different metals. The dopant can be selected from the group of oxygen, nitrogen, or combinations thereof. The metalloid, first metal, second metal, and dopant can account for at least 70 at % of the amorphous thin metal film. |
| FILED | Friday, June 24, 2016 |
| APPL NO | 16/067788 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/1606 (20130101) B41J 2/1646 (20130101) B41J 2/14129 (20130101) Original (OR) Class B41J 2202/03 (20130101) Alloys C22C 45/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/08 (20130101) C23C 14/0036 (20130101) C23C 14/185 (20130101) C23C 28/04 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US D863965 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Jim E. Lee (Washington, District of Columbia); Robert E. Dixon, Jr. (Washington, District of Columbia); Jon Goodrich (Washington, District of Columbia) |
| ABSTRACT | |
| FILED | Wednesday, January 04, 2017 |
| APPL NO | 29/589758 |
| ART UNIT | 2919 — Design |
| CURRENT CPC | Packages and containers for goods D9/456 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, October 22, 2019.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20191022.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page