FedInvent™ Patents
Patent Details for Tuesday, November 05, 2019
This page was updated on Monday, March 27, 2023 at 05:56 AM GMT
Department of Health and Human Services (HHS)
| US 10463247 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Wenzhou Medical University (Zhejiang, China PRC) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zhongping Chen (Irvine, California); Lu Fan (Zhejiang, China PRC); Shenghai Huang (Zhejiang, China PRC) |
| ABSTRACT | A three-dimensional (three dimensional) segmentation method with intensity-based Doppler variance (IBDV) based on swept-source OCT. The automatic three dimensional segmentation method is used to obtain seven surfaces of intra-retinal layers. The microvascular network of the retina, which is acquired by the IBDV method, can be divided into six layers. The microvascular network of the six individual layers are visualized, and the morphology and contrast images can be improved by using the segmentation method. This method has potential for earlier diagnosis and precise monitoring in retinal vascular diseases. Each tomographic image is composed of eight repeat scans at the same position, which achieves a high time difference to improve the sensitivity of the angiographic method. A subpixel registration algorithm is used to reduce the eye movement. The GPU was used to accelerate the data processing to achieve real-time preview of the acquired data. |
| FILED | Tuesday, June 21, 2016 |
| APPL NO | 15/188839 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/102 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463256 | Kanick et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Stephen Chad Kanick (Lebanon, New Hampshire); Brian William Pogue (Hanover, New Hampshire); Keith D. Paulsen (Hanover, New Hampshire); Jonathan T. Elliott (West Lebanon, New Hampshire); David M. McClatchy, III (Hanover, New Hampshire); Venkataramanan Krishnaswamy (Lebanon, New Hampshire) |
| ABSTRACT | A method for determining sub-diffuse scattering parameters of a material includes illuminating the material with structured light and imaging remission by the material of the structured light. The method further includes determining, from captured remission images, sub-diffuse scattering parameters of the material. A structured-light imaging system for determining sub-diffuse scattering parameters of a material includes a structured-light illuminator, for illuminating the material with structured light of periodic spatial structure, and a camera for capturing images of the remission of the structured light by the material. The structured-light imaging system further includes an analysis module for processing the images to quantitatively determine the sub-diffuse scattering parameters. A software product includes machine-readable instructions for analyzing images of remission of structured light by a material to determine sub-diffuse scattering parameters of the material. |
| FILED | Tuesday, February 02, 2016 |
| APPL NO | 15/013623 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) Original (OR) Class A61B 2576/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463264 | Swoboda |
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| FUNDED BY |
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| APPLICANT(S) | Aqueduct Critical Care, Inc. (Bothell, Washington) |
| ASSIGNEE(S) | Aqueduct Critical Care, Inc. (Bothell, Washington) |
| INVENTOR(S) | Marek Swoboda (Philadelphia, Pennsylvania) |
| ABSTRACT | An implantable pressure sensor that wirelessly provides pressure data to a wireless receiver. The pressure sensor includes a first flexible membrane exposed to the region whose pressure is being monitored. In contact with this first flexible membrane is a force transducer, for measuring this pressure, that is itself suspended on an internal flexible membrane. This internal flexible membrane allows the force transducer to not only be displaced away from the first flexible membrane, but it allows for the force transducer to also be oscillated, either out-of-contact with the first flexible membrane or in-contact therewith for static/dynamic pressure sensor calibration. Another embodiment suspends an internal housing on a third flexible membrane wherein the internal flexible membrane forms the upper surface of the internal housing. An actuator for displacing/oscillating the force transducer is located within the internal housing. This permits establishing a constant distance between the force transducer and the actuator. |
| FILED | Tuesday, October 14, 2014 |
| APPL NO | 15/029592 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0017 (20130101) A61B 5/0031 (20130101) A61B 5/031 (20130101) Original (OR) Class A61B 5/6861 (20130101) A61B 2560/0238 (20130101) A61B 2562/0247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463279 | Chapman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Ryan Chapman (West Lebanon, New Hampshire); Douglas Wayne Van Citters (Hanover, New Hampshire); Wayne Edward Moschetti (Hanover, New Hampshire); John-Erik Bell (Hanover, New Hampshire) |
| ABSTRACT | Systems and methods for monitoring a range of motion of a joint are described. For example, in one embodiment, a first set of sensors may sense accelerations of a first body portion located on a first side of the joint and a second set of sensors may sense accelerations of the second body portion located on a second opposing side of the joint. The acceleration data may then be used to compute the relative motion of the first and second body portions to determine movement of the joint. This joint movement may then be used to determine one or more range of motion movement metrics which are output for viewing by a subject or medical practitioner. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/436577 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0024 (20130101) A61B 5/1121 (20130101) Original (OR) Class A61B 5/4576 (20130101) A61B 5/4585 (20130101) A61B 2562/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463317 | Tian et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Xiaoyu Tian (Durham, North Carolina); Ehsan Samei (Durham, North Carolina); Paul Segars (Durham, North Carolina) |
| ABSTRACT | Systems and methods for estimating irradiation dose for patient application based on a radiation field model and a patient anatomy model are disclosed. According to an aspect, a method includes providing a database of patient anatomy models. The method also includes providing a radiation field model of an X-ray system. Further, the method includes receiving a measure of an anatomy of a patient. The method also includes determining a patient anatomy model among the patient anatomy models that matches or is similar to the anatomy of the patient based on the measure of the patient and a corresponding measure of each of the patient anatomy models. The method also includes estimating an irradiation dose for application to the patient by the X-ray system based on the radiation field model and the determined patient anatomy model. |
| FILED | Monday, October 03, 2016 |
| APPL NO | 15/283708 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) Original (OR) Class A61B 6/50 (20130101) A61B 6/544 (20130101) A61B 6/545 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463334 | Shaughnessy |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Gabriel Grant Shaughnessy (Nashotah, Wisconsin) |
| ABSTRACT | A system and method are provided for generating time resolved series of angiographic volume data having flow information. The system and method are configured to receive angiographic volume data acquired from a subject having received a dose of a contrast agent using an imaging system and process the angiographic volume data to generate angiographic volume images. The angiographic volume data is processed to select a seed vessel in the vessel network, determine a plurality of branch vessels connected to the seed vessel and extending to form a vessel network, determine independent and dependent vessels in the vessel network, apply a flow model to the vessel network, and generate a flow map to be displayed with the angiographic volume images to illustrate time-resolved vascular volumes displaying flow within the vessel network. |
| FILED | Tuesday, January 16, 2018 |
| APPL NO | 15/872457 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/021 (20130101) A61B 5/029 (20130101) A61B 5/0285 (20130101) A61B 5/02014 (20130101) A61B 6/481 (20130101) A61B 6/486 (20130101) A61B 6/504 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463495 | Rogers et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Toby Rogers (Washington, District of Columbia); Robert J. Lederman (Chevy Chase, Maryland); Merdim Sonmez (Bethesda, Maryland); Dominique N. Franson (Gaithersburg, Maryland); Ozgur Kocaturk (Rockville, Maryland) |
| ABSTRACT | Delivery devices for delivering encircling implants can include two separate limbs that are held together at a distal articulation by the implant being delivered. The implant can comprise a suture and/or a braided tube. The implant can extend through or over the limbs. The implant and at least a distal portion of the limbs can be compressible into a delivery shape that allows for advancement through the lumen of a delivery catheter. When the distal portion of the limbs move out of the delivery catheter, the limbs and implant can resiliently assume a loop shape that is complementary to a shape of a target around which the encircling implant is to be placed. The limbs are then retracted from along the implant to leave the implant in the desired delivery position. The delivery device can be used to place encircling implants around the heart or other targets, and the implant can be tightened to exert compressive force on the target. |
| FILED | Tuesday, June 03, 2014 |
| APPL NO | 14/898020 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/221 (20130101) A61B 17/00234 (20130101) A61B 2017/00243 (20130101) A61B 2017/00278 (20130101) A61B 2017/00292 (20130101) A61B 2017/00358 (20130101) A61B 2017/2212 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2481 (20130101) Original (OR) Class A61F 2002/2484 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463684 | Cui et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNEVERSETY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Zhengrong Cui (Austin, Texas); Dharmika S. P. Lansakara-P. (Austin, Texas) |
| ABSTRACT | Disclosed herein are derivatives of nucleobase analogs. The disclosed compounds have a nucleobase moiety and an omega-3 polyunsaturated fatty acid moiety, including pharmaceutically acceptable salt or prodrug thereof. Methods of using these compounds for the treatment of cancers such as pancreatic cancer are also disclosed. |
| FILED | Thursday, January 29, 2015 |
| APPL NO | 15/115393 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7068 (20130101) Original (OR) Class A61K 47/542 (20170801) Heterocyclic Compounds C07D 401/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463687 | Rodriguez-Boulan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Enrique Rodriguez-Boulan (New York, New York); Marcelo Nociari (Summit, New Jersey) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Enrique Rodriguez-Boulan (New York, New York); Marcelo Nociari (Summit, New Jersey) |
| ABSTRACT | The present invention relates to the use of cyclic oligosaccharides as chemical complexants of lipofuscin bisretinoids (A2E) to prevent and treat eye (i.e., retinal or macular) disease. Monomeric, dimeric, multimeric, or polymeric oligosaccharide rings act as pharmacologic agents to prevent and treat ophthalmologic disorders triggered by the accumulation of lipofuscin in the retinal pigment epithelium (RPE), which occurs as a consequence of either genetic disorders, such as Stargardt Disease (SD) and Best Disease (BD), or aging, such as Age-Related Macular Degeneration (AMD), or other diseases, such as retinitis pigmentosa, and cone-rod dystrophy. |
| FILED | Friday, January 20, 2012 |
| APPL NO | 13/980687 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/724 (20130101) Original (OR) Class A61K 47/6951 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463688 | Gellman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Samuel H. Gellman (Madison, Wisconsin); Runhui Liu (Madison, Wisconsin); Bernard Weisblum (Madison, Wisconsin); Shonna M. McBride (Atlanta, Georgia) |
| ABSTRACT | A method and corresponding composition to inhibit outgrowth of C. difficile spores and/or to inhibit growth of C. difficile vegetative cells in a mammal in which an amount of a nylon-3 polymer or nylon-3 copolymer or a pharmaceutically suitable salt thereof is administered to the subject. |
| FILED | Thursday, June 30, 2016 |
| APPL NO | 15/198588 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/787 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463694 | Luo et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Syracuse, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Syracuse, New York) |
| INVENTOR(S) | Juntao Luo (Jamesville, New York); Changying Shi (Jamesville, New York); Dandan Guo (Syracuse, New York) |
| ABSTRACT | Provided are multiply functional telodendrimers. The telodendrimers can be used for combination drug delivery. The telodendrimers may have one or more crosslinking groups (e.g., reversible photocrosslinking groups). The telodendrimers can aggregate to form nanocarriers. Cargo such as combinations of drugs, imaging probes, and other materials may be sequestered in the core of the aggregates via non-covalent or covalent interactions with the telodendrimers. Such nanocarriers may be used in drug delivery applications and imaging applications. |
| FILED | Wednesday, October 07, 2015 |
| APPL NO | 15/517544 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/107 (20130101) A61K 31/337 (20130101) A61K 33/24 (20130101) Original (OR) Class A61K 47/34 (20130101) A61K 47/60 (20170801) A61K 47/595 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463698 | Bernstein et al. |
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| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Irwin D. Bernstein (Seattle, Washington); Brandon K. Hadland (Seattle, Washington) |
| ABSTRACT | The present invention relates to methods, kits and compositions for expansion of embryonic hematopoietic stem cells and providing hematopoietic function to human patients in need thereof. In one aspect, it relates to kits and compositions comprising a Notch agonist, one or more growth factors, and, optionally, an inhibitor of the TGFβ pathway. Also provided herein are methods for expanding embryonic hematopoietic stem cells using kits and compositions comprising a Notch agonist, one or more growth factors, and, optionally, an inhibitor of the TGFβ pathway. The embryonic hematopoietic stem cells expanded using the disclosed kits, compositions and methods include cells derived from an embryo (e.g., aorta-gonad-mesonephros region of the embryo), embryonic stem cells, induced pluripotent stem cells, or reprogrammed cells of other types. The present invention also relates to administering the embryonic hematopoietic stem cells expanded using a combination of a Notch agonist, one or more growth factors, and, optionally, an inhibitor of the TGFβ pathway to a patient for short-term and/or long-term in vivo repopulation benefits. |
| FILED | Wednesday, March 28, 2018 |
| APPL NO | 15/939199 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 2035/124 (20130101) Peptides C07K 14/52 (20130101) C07K 14/54 (20130101) C07K 14/475 (20130101) C07K 14/5403 (20130101) C07K 14/5412 (20130101) C07K 14/5431 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0647 (20130101) C12N 2501/10 (20130101) C12N 2501/15 (20130101) C12N 2501/26 (20130101) C12N 2501/42 (20130101) C12N 2501/125 (20130101) C12N 2501/145 (20130101) C12N 2501/2301 (20130101) C12N 2501/2303 (20130101) C12N 2501/2306 (20130101) C12N 2501/2311 (20130101) C12N 2533/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463716 | Gong et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Da-Wei Gong (Olney, Maryland); Daozhan Yu (Ellicott City, Maryland); Rongze Yang (Ellicott City, Maryland); Alan Shuldiner (Baltimore, Maryland); Ling Chen (Ellicott City, Maryland) |
| ABSTRACT | The present invention generally to methods of treating subjects suffering from a cardiac condition or having a risk factor for developing a cardiac condition by administering an ELA peptide or fusion protein to a subject in need. The invention relates to fusion proteins of Fc-ELA-32 and Fc-ELA-21 that exhibit improved properties for use as therapeutic agents, e.g. in the treatment of cardiac conditions. In addition, the present invention relates to polynucleotides encoding such fusion proteins, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the fusion proteins of the invention, and to methods of using them in the treatment of disease. |
| FILED | Tuesday, October 13, 2015 |
| APPL NO | 15/519021 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/16 (20130101) A61K 38/22 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) A61P 9/02 (20180101) A61P 9/04 (20180101) A61P 9/06 (20180101) A61P 9/10 (20180101) A61P 9/12 (20180101) Peptides C07K 14/47 (20130101) C07K 14/575 (20130101) C07K 14/4705 (20130101) C07K 14/4722 (20130101) C07K 19/00 (20130101) C07K 2319/02 (20130101) C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) G01N 33/6893 (20130101) G01N 2800/32 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463722 | Del Poeta et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Maurizio Del Poeta (Mount Sinai, New York); Antonella Rella (Port Jefferson Station, New York) |
| ABSTRACT | The present disclosure provides compositions comprising mutant fungi include an inactive form of the sterylglucosidase enzyme. The present disclosure is also directed to vaccine based compositions, which include a mutant fungus that prohibit pathogenic fungal infection. This disclosure also provides methods for administering these compositions as a prophylaxis against fungal infection, as well as methods for isolating sterylglucosides that include the use of such mutant fungal compositions. |
| FILED | Thursday, August 10, 2017 |
| APPL NO | 15/673937 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0002 (20130101) Original (OR) Class A61K 2039/52 (20130101) A61K 2039/522 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/44 (20130101) C12P 19/56 (20130101) C12P 33/00 (20130101) Enzymes C12Y 302/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463724 | Tuohy et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | Vincent K. Tuohy (Broadview Heights, Ohio); Justin M. Johnson (Willoughby Hills, Ohio); Ritika Jaini (Cleveland, Ohio) |
| ABSTRACT | Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human α-lactalbumin. |
| FILED | Friday, September 11, 2015 |
| APPL NO | 14/851674 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/572 (20130101) A61K 2039/55577 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463729 | Harrison et al. |
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| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Stephen C. Harrison (Brighton, Massachusetts); Bing Chen (Chestnut Hill, Massachusetts); Dan H. Barouch (Boston, Massachusetts); Joseph P. Nkolola (Watertown, Massachusetts); Michael Scott Seaman (West Roxbury, Massachusetts) |
| ABSTRACT | Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided. |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 16/385438 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16051 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463734 | Petty |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Howard R. Petty (Livonia, Michigan) |
| ABSTRACT | Nanoparticles comprising a metal oxide and a platinum cluster having a height to base ratio greater than 1 and compositions containing the same are disclosed. Methods of using the nanoparticles in producing hydroxyl radicals and in photodynamic therapy, for example, in the treatment of hyperproliferative disease such cancer, are also disclosed. |
| FILED | Friday, April 24, 2015 |
| APPL NO | 14/695951 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) A61K 9/143 (20130101) A61K 33/24 (20130101) A61K 33/24 (20130101) A61K 33/26 (20130101) A61K 33/26 (20130101) A61K 33/30 (20130101) A61K 33/30 (20130101) A61K 41/0057 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0662 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/6527 (20130101) B01J 35/006 (20130101) B01J 37/345 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 1/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463747 | Celis |
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| FUNDED BY |
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| APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| INVENTOR(S) | Esteban Celis (Tampa, Florida) |
| ABSTRACT | The invention describes the development of more potent peptide vaccines to prevent or treat infections or cancer and their administration to a subject in order to elicit a T cell response in the subject. Small synthetic peptides from the known sequences of viral, bacterial, parasitic or tumor antigens are modified so they can spontaneously form complexes with a synthetic nucleic acid, such as Poly IC, that functions as an immunological adjuvant. The peptide-nucleic acid complexes are dramatically more immunogenic as compared to the separate components. The procedure for developing the vaccine involves the conjugation of a synthetic peptide containing a C residue to poly-K using a bi-functional cross-linking reagent (SMCC). The peptide/poly-K complex was then formulated with CMC and poly-IC to produce a self-adjuvant vaccine that was 36-fold more effective as compared to the same peptide administered mixed with the same adjuvant (but not complexed to it). |
| FILED | Monday, August 21, 2017 |
| APPL NO | 15/682029 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 47/55 (20170801) A61K 47/61 (20170801) A61K 47/549 (20170801) A61K 47/645 (20170801) A61K 47/646 (20170801) Original (OR) Class A61K 47/6455 (20170801) A61K 2039/57 (20130101) A61K 2039/627 (20130101) A61K 2039/55561 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463750 | Schneck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Jonathan Schneck (Baltimore, Maryland); Christian Schuetz (Baltimore, Maryland) |
| ABSTRACT | This disclosure describes compositions and methods for selectively recruiting antigen-specific T cells and re-direct them to kill targeted cells, particularly tumor cells. This approach permits selective engagement of specific effector cell populations and, by using nanoparticles, overcomes the geometric limitations associated with previous approaches. |
| FILED | Friday, February 14, 2014 |
| APPL NO | 14/767342 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6891 (20170801) A61K 47/6923 (20170801) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/18 (20130101) C07K 16/30 (20130101) C07K 16/2833 (20130101) C07K 2317/21 (20130101) C07K 2319/00 (20130101) C07K 2319/01 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463856 | Towe |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Bruce C. Towe (Mesa, Arizona) |
| ABSTRACT | Some embodiments include a dipolar antenna system to electrically power an implantable miniature device and/or to stimulate bioelectrically excitable tissue, such as, for example, through microelectronic neurostimulation. Other related systems and methods are also disclosed. |
| FILED | Tuesday, June 13, 2017 |
| APPL NO | 15/621208 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3605 (20130101) Original (OR) Class A61N 1/3787 (20130101) A61N 1/37205 (20130101) A61N 1/37223 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49018 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463878 | Bazard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Parveen Bazard (Tampa, Florida); Robert Dana Frisina (Tampa, Florida); Joseph Paul Walton (Tampa, Florida); Venkat Rama Bhethanabotla (Tampa, Florida) |
| ABSTRACT | A novel method to stimulate electrically active biological cells using visible wavelength light and metallic nanoparticles possessing plasmonic properties is presented herein. Using this technology, prosthetic devices such as cochlear and retinal implants and cardiac pacemakers can be developed to have superior properties as compared to the currently utilized electrical stimulation designs. These properties include improved spatial resolution; less or non-invasive devices; and higher fidelity of transduction. An additional advantage of using visible light wavelengths is the avoidance of unwanted heating of surrounding tissue that occurs with infrared stimulation. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 15/912692 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0603 (20130101) A61N 5/0622 (20130101) Original (OR) Class A61N 2005/063 (20130101) A61N 2005/067 (20130101) A61N 2005/0605 (20130101) A61N 2005/0663 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464064 | Wikswo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Dmitry A. Markov (Nashville, Tennessee); Ronald S. Reiserer (Nashville, Tennessee) |
| ABSTRACT | In certain aspects of the invention, a stackable device includes multiple elements stacked sequentially. A chamber is formed in each of the elements or between adjacent two of the elements, and each chamber is in fluid communication with an input channel and an output channel. The chambers are aligned with each other, and adjacent two chambers are separated from each other by a membrane. In certain aspects of the invention, a system includes at least one stackable device, each stackable device having multiple chambers; and at least one of a perfusion controller, a microformulator, and a microclinical analyzer in fluid communication with the at least one stackable device. In other aspects of the invention, the use of four microformulators, electrodes and an impedance analyzer can measure the impedance spectrum of each barrier in a multi-transwell plate. |
| FILED | Monday, July 15, 2019 |
| APPL NO | 16/511379 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50255 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 9/00 (20130101) B01L 2300/0816 (20130101) B01L 2300/0874 (20130101) B01L 2300/0887 (20130101) B01L 2400/0415 (20130101) B01L 2400/0472 (20130101) B01L 2400/0487 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 23/34 (20130101) C12M 29/04 (20130101) C12M 29/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/00 (20130101) G01N 27/026 (20130101) G01N 33/54366 (20130101) G01N 35/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464307 | Chung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Peter Chung (San Diego, California); Xin Qu (Houston, Texas); Aping Zhang (Hangzhou, China PRC); Shaochen Chen (San Diego, California) |
| ABSTRACT | A system and method for 3D microfabrication projects light capable of initiating photopolymerization toward a spatial light modulator that modulates light responsive to digital masks corresponding to layers of the structure. Projection optics focus the modulated light onto an optical plane within a photopolymerizable material supported on a stage. A computer controller causes the spatial light modulator to project a sequence of images corresponding to the digital masks while coordinating movement of the stage to move a position of the optical plane within the photopolymerizable material to sequentially project each image of the sequence to generate the structure by progressively photopolymerizing the photopolymerizable material. |
| FILED | Wednesday, May 20, 2015 |
| APPL NO | 15/311135 |
| ART UNIT | 1748 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0805 (20130101) B29C 35/0894 (20130101) B29C 64/40 (20170801) B29C 64/129 (20170801) B29C 64/277 (20170801) B29C 64/386 (20170801) B29C 2035/0827 (20130101) B29C 2035/0838 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0005 (20130101) B29K 2995/0056 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/752 (20130101) B29L 2031/7532 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/5058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464881 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); ALCHEM LABORATORIES CORPORATION (Alachua, Florida) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); ALCHEM LABORATORIES CORPORATION (Alachua, Florida) |
| INVENTOR(S) | Paul S. Liu (Bethesda, Maryland); Sergiy M. Denysenko (Alachua, Florida); Guangfei Huang (Alachua, Florida) |
| ABSTRACT | Disclosed is a process for preparing (Z)-endoxifen, comprising (i) recrystallizing an input crystalline solid comprising a mixture of (Z)-endoxifen (1) and (E)-endoxifen (2) from a first solvent to provide a first crystalline solid and a first mother liquor, wherein the first mother liquor has a ratio of (1) to (2) at least 1.3 times greater than the ratio in the input crystalline solid (1) and (2); (ii) recrystallizing a solid produced by concentrating the first mother liquor, or by removal of the first solvent from the first mother liquor, from a second solvent to give a second crystalline solid and a second mother liquor; (iii) optionally recrystallizing the second crystalline solid from the second solvent one to five additional times to give a third crystalline solid; wherein the third crystalline solid has a ratio of (Z)-endoxifen (1) to (E)-endoxifen (2) greater than 20:1. |
| FILED | Monday, October 24, 2016 |
| APPL NO | 15/770274 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/09 (20130101) Acyclic or Carbocyclic Compounds C07C 41/30 (20130101) C07C 41/30 (20130101) C07C 43/23 (20130101) C07C 45/455 (20130101) C07C 45/455 (20130101) C07C 49/84 (20130101) C07C 213/02 (20130101) C07C 213/02 (20130101) C07C 213/10 (20130101) Original (OR) Class C07C 213/10 (20130101) C07C 217/18 (20130101) C07C 217/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464890 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Jing Chen (Atlanta, Georgia); Taro Hitosugi (Decatur, Georgia); Sumin Kang (Decatur, Georgia) |
| ABSTRACT | In certain embodiments, the disclosure relates to methods of treating or preventing a PGAM1 mediated condition such as cancer or tumor growth comprising administering an effective amount of PGAM1 inhibitor, for example, an anthracene-9,10-dione derivative to a subject in need thereof. In certain embodiments, the disclosure relates to methods of treating or preventing cancer, such as lung cancer, head and neck cancer, and leukemia, comprising administering a therapeutically effective amount of a pharmaceutical composition comprising a compound disclosed herein or pharmaceutically acceptable salt to a subject in need thereof. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/847670 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 311/29 (20130101) Original (OR) Class C07C 2603/24 (20170501) Peptides C07K 16/40 (20130101) C07K 2317/34 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 1/06 (20130101) C09B 1/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464925 | Bradner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | James Bradner (Weston, Massachusetts); Dennis Buckley (Jamaica Plains, Massachusetts); Georg Winter (Brookline, Massachusetts) |
| ABSTRACT | The present application provides bifunctional compounds which act as protein degradation inducing moieties. The present application also relates to methods for the targeted degradation of endogenous proteins through the use of the bifunctional compounds that link a cereblon-binding moiety to a ligand that is capable of binding to the targeted protein which can be utilized in the treatment of proliferative disorders. The present application also provides methods for making compounds of the application and intermediates thereof. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/863760 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/00 (20180101) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class C07D 471/04 (20130101) C07D 471/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464930 | Thatcher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Gregory R. Thatcher (Chicago, Illinois); Marton Siklos (Chicago, Illinois); Rui Xiong (Chicago, Illinois) |
| ABSTRACT | Disclosed is a compound of formula (I). or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions including the compound of formula (I) and methods of using the compound of formula (I). |
| FILED | Wednesday, October 31, 2018 |
| APPL NO | 16/177112 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 333/56 (20130101) C07D 333/64 (20130101) C07D 409/04 (20130101) C07D 409/08 (20130101) C07D 409/12 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 2333/91205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464941 | Portoghese et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Philip S. Portoghese (Minneapolis, Minnesota); Eyup Akgun (Minneapolis, Minnesota) |
| ABSTRACT | and salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods using a compound of formula I. |
| FILED | Wednesday, February 24, 2016 |
| APPL NO | 15/553524 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) A61K 31/4545 (20130101) A61K 45/06 (20130101) A61K 47/54 (20170801) A61K 47/55 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Heterocyclic Compounds C07D 489/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464949 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael S. Gray (Boston, Massachusetts); Sara Jean Buhrlage (Somerville, Massachusetts); Steven P. Treon (Jamaica Plain, Massachusetts); Hwan Geun Choi (Chestnut Hill, Massachusetts); Yuan Xiong (Brookline, Massachusetts); Guang Yang (Natick, Massachusetts) |
| ABSTRACT | The present disclosure provides thiazolyl-containing compounds of Formula (I), (II), or (III). The compounds described herein may be able to inhibit protein kinases (e.g., Src family kinases (e.g., hemopoietic cell kinase (HCK)), Bruton's tyrosine kinase (BTK)) and may be useful in treating and/or preventing proliferative diseases (e.g., myelodysplasia, leukemia, lymphoma (e.g., Waldenström's macroglobulinemia)) and in inducing apoptosis in a cell (e.g., malignant blood cell). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein. |
| FILED | Wednesday, October 24, 2018 |
| APPL NO | 16/169972 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Heterocyclic Compounds C07D 417/04 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) C07D 513/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464952 | Burns et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VenatoRx Pharmaceuticals, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | VENATORX PHARMACEUTICALS, INC. (Malvern, Pennsylvania) |
| INVENTOR(S) | Christopher J. Burns (Malvern, Pennsylvania); Daniel C. Pevear (Downingtown, Pennsylvania); Robert E. Lee Trout (Collegeville, Pennsylvania); Randy W. Jackson (Livingston, Montana); Jodie Hamrick (New Holland, Pennsylvania); Allison L. Zulli (Chesterbrook, Pennsylvania); Eugen F. Mesaros (Wallingford, Pennsylvania); Steven A. Boyd (Chester Springs, Pennsylvania) |
| ABSTRACT | Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections. |
| FILED | Thursday, June 07, 2018 |
| APPL NO | 16/002363 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/43 (20130101) A61K 31/69 (20130101) A61K 31/69 (20130101) A61K 31/427 (20130101) A61K 31/427 (20130101) A61K 31/545 (20130101) A61K 31/545 (20130101) A61K 31/546 (20130101) A61K 31/546 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464967 | McCall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Reveragen Biopharma, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | ReveraGen BioPharma, Inc. (Rockville, Maryland) |
| INVENTOR(S) | John M. McCall (Boca Grande, Florida); Eric Hoffman (Kensington, Maryland); Nagaraju (Raju) Kanneboyina (Kensington, Maryland); Jesse Damsker (Washington, District of Columbia) |
| ABSTRACT | The present invention relates to compounds and methods which may be useful as treatments of diseases. |
| FILED | Thursday, November 29, 2012 |
| APPL NO | 14/360384 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/573 (20130101) Steroids C07J 7/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464970 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Yun-Xing Wang (Columbia, Maryland); Ping Yu (Frederick, Maryland) |
| ABSTRACT | Compounds (such as peptides or peptide mimetics) that bind to HIV RRE RNA are provided. In some examples, the compounds inhibit (for example, decrease) binding of Rev to the RRE RNA. In some embodiments, the compounds include two moieties, each of which bind to one of the Rev binding sites in the RRE. In some examples, the moieties include peptides or small molecules. In some examples, the peptides include an arginine-rich motif. The RRE binding compounds may be further linked to a detectable label or cargo moiety. Also provided are methods of treating or inhibiting HIV including administering one or more of the RRE binding compounds to a subject. |
| FILED | Thursday, October 23, 2014 |
| APPL NO | 15/031232 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/17 (20130101) A61K 45/06 (20130101) A61K 47/64 (20170801) A61K 49/14 (20130101) A61K 49/0056 (20130101) A61K 51/088 (20130101) Peptides C07K 14/00 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16011 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) G01N 2333/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464971 | Schneewind et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Olaf Schneewind (Chicago, Illinois); Alice G. Cheng (Boston, Massachusetts); Dominique M. Missiakas (Chicago, Illinois); Hwan Keun Kim (Chicago, Illinois) |
| ABSTRACT | The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant. |
| FILED | Tuesday, September 12, 2017 |
| APPL NO | 15/702037 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/085 (20130101) A61K 2039/57 (20130101) Peptides C07K 14/31 (20130101) Original (OR) Class C07K 16/1271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464982 | Galipeau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Jacques Galipeau (Atlanta, Georgia); Andrea Pennati (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to recombinant proteins comprising a GM-CSF sequence and an interleukin sequence and nucleic acids related thereto. In certain embodiments, the disclosure relates to recombinant proteins comprises N-terminal sequences that are the result of improved production techniques and uses for treating or preventing autoimmune diseases such as multiple sclerosis and cancer. |
| FILED | Monday, April 13, 2015 |
| APPL NO | 15/305714 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/17 (20130101) A61K 38/00 (20130101) A61K 39/0008 (20130101) A61K 45/06 (20130101) A61K 2039/515 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/55 (20130101) C07K 14/535 (20130101) Original (OR) Class C07K 14/5406 (20130101) C07K 14/5425 (20130101) C07K 14/5443 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464983 | Pioszak |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Augen A. Pioszak (Edmond, Oklahoma) |
| ABSTRACT | Variant peptides of calcitonin gene-related peptide alpha (αCGRP), calcitonin gene-related peptide beta (βCGRP), and adrenomedullin (AM) are disclosed, wherein the variant peptides have high binding affinity and agonistic or antagonistic activity for at least one receptor complex of CLR:RAMP1, CLR:RAMP2, and CLR:RAMP3. Also disclosed are methods of use of the variant peptides in therapeutic treatments. |
| FILED | Friday, May 13, 2016 |
| APPL NO | 15/568129 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/575 (20130101) C07K 14/585 (20130101) Original (OR) Class C07K 14/57527 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464985 | Miao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Yubin Miao (Albuquerque, New Mexico); Haixun Guo (Louisville, Kentucky) |
| ABSTRACT | The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states. |
| FILED | Thursday, July 19, 2018 |
| APPL NO | 16/039858 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 51/08 (20130101) A61K 51/086 (20130101) A61K 51/088 (20130101) Peptides C07K 7/54 (20130101) C07K 14/68 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464987 | Kranz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David M. Kranz (Champaign, Illinois); David H. Aggen (Savoy, Illinois) |
| ASSIGNEE(S) | AbbVie Inc. (Chicago, Illinois) |
| INVENTOR(S) | David M. Kranz (Champaign, Illinois); David H. Aggen (Savoy, Illinois) |
| ABSTRACT | A soluble human single-chain T cell receptor (TCR) having the structure: Vα2-L-Vβ or Vβ-L-Vα2, wherein L is a linker peptide that links Vβ with Vα, Vβ is a TCR variable β region, and Vα2 is a TCR variable α region of the family 2 is provided. The provided scTCR is useful for many purposes, including the treatment of cancer, viral diseases and autoimmune diseases. |
| FILED | Wednesday, October 06, 2010 |
| APPL NO | 13/500123 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/7051 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464993 | Lefrancois et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| ASSIGNEE(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Leo Lefrancois (West Hartford, Connecticut); Thomas A. Stoklasek (Bristol, Connecticut) |
| ABSTRACT | The present invention relates to a therapeutic polypeptide and methods for its creation and use for modulating an immune response in a host organism in need thereof. In particular, the invention relates to the administration to an organism in need thereof, of an effective amount of a pre-coupled polypeptide complex comprising a lymphokine polypeptide portion, for example IL-15 (SEQ ID NO: 5, 6), IL-2 (SEQ ID NO: 10, 12) or combinations of both, and an interleukin receptor polypeptide portion, for example IL-15Ra (SEQ ID NO: 7, 8), IL-2Ra (SEQ ID NO: 9, 11) or combinations of both, for augmenting the immune system in, for example, cancer, SCID, AIDS, or vaccination; or inhibiting the immune system in, for example, rheumatoid arthritis, or Lupus. The therapeutic complex of the invention surprisingly demonstrates increased half-life, and efficacy in vivo. |
| FILED | Thursday, April 05, 2018 |
| APPL NO | 15/946402 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1793 (20130101) A61K 38/2086 (20130101) Peptides C07K 1/02 (20130101) C07K 14/55 (20130101) C07K 14/5443 (20130101) C07K 14/7155 (20130101) Original (OR) Class C07K 16/00 (20130101) C07K 2317/52 (20130101) C07K 2319/02 (20130101) C07K 2319/30 (20130101) C07K 2319/31 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465005 | Parkos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory Patent Group (Atlanta, Georgia) |
| INVENTOR(S) | Charles A. Parkos (Norcross, Georgia); Dominique A. Weber (Atlanta, Georgia) |
| ABSTRACT | Certain embodiments of the disclosure relate to targeted binding agents that specifically bind to JAM-like protein and therein inhibit epithelial damage. Although it is not intended that embodiments of the disclosure be limited by any particular mechanism, it is believed that a possible mechanism by which this can be achieved may include, but are not limited to, either inhibition of binding of JAML to the CAR, inhibition of JAML induced CAR signaling, or increased clearance of JAML from the body of a subject, therein reducing the effective concentration of soluble JAML. In certain embodiment, the specific binding agent is a fully human antibody or chimera that specifically binds to human JAML, such as the JAML D1, and prevents JAML binding to CAR. Certain embodiments of the disclosure contemplate antibodies comprising human IgG type, e.g., IgG1, IgG2, IgG3, and IgG4. |
| FILED | Tuesday, March 14, 2017 |
| APPL NO | 15/458113 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465042 | Cui et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Jiajia Cui (New Haven, Connecticut); Junwei Zhang (New Haven, Connecticut); W. Mark Saltzman (New Haven, Connecticut) |
| ABSTRACT | Polymers including poly(amine-co-ester), poly(amine-co-amide), or a combination thereof, and nanoparticles, particularly solid core nanoparticles, formed therefrom are provided. Solid core nanoparticles fabricated from hydrophobic polymers often require the presence of cationic complexing agents to stabilize negatively charged active agents such as siRNA. However, complexing agents are optional in the disclosed formulations because the nanoparticles contain cationic amines to stabilize negatively charged nucleic acids and hydrophobic domains to condense the nucleic acid into the core of the formed nanoparticles, thus improving encapsulation efficiency. This increase in nucleic acid loading allows the disclosed solid core nanoparticles to deliver more nucleic acid per cell without increasing total polymer delivered, further reducing cytotoxicity. Pharmaceutical compositions including an effective amount of the nanoparticles are also provided, and be used, for example, for in vitro and in vivo delivery of nucleic acids. |
| FILED | Wednesday, May 11, 2016 |
| APPL NO | 15/152228 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5153 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/685 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465166 | Ince |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| INVENTOR(S) | Tan Ince (Miami, Florida) |
| ABSTRACT | A cell culture medium comprising adenosine triphosphate; a carrier protein; cholesterol, linoleic acid, and lipoic acid; glutathione; at least one nucleotide salvage pathway precursor base; phosphoethanolamine; selenium; transferrin; triiodothyronine; all-trans-retinoic acid (ATRA) and vitamin C; zinc, magnesium, and copper; an agent that increases intracellular cAMP; epidermal growth factor (EGF); hydrocortisone; insulin; and charcoal stripped fetal bovine serum, wherein said cell culture medium is substantially free, if not entirely free, of vitamin D, androgenic hormones, androgenic ligands, estrogenic hormones, estrogenic ligands, and/or androgenic receptors. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/687150 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0631 (20130101) Original (OR) Class C12N 5/0693 (20130101) C12N 2500/16 (20130101) C12N 2500/20 (20130101) C12N 2500/22 (20130101) C12N 2500/24 (20130101) C12N 2500/36 (20130101) C12N 2500/38 (20130101) C12N 2500/42 (20130101) C12N 2500/46 (20130101) C12N 2501/01 (20130101) C12N 2501/11 (20130101) C12N 2501/33 (20130101) C12N 2501/39 (20130101) C12N 2501/392 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465170 | Peeples et al. |
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| FUNDED BY |
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| APPLICANT(S) | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio); OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio); Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
| INVENTOR(S) | Mark E. Peeples (Bexley, Ohio); Jianrong Li (Dublin, Ohio); Hui Cai (Columbus, Ohio); Rongzhang Wang (Columbus, Ohio) |
| ABSTRACT | Described herein are mutant pneumoviruses comprising a nucleotide sequence which encodes a mutated zinc binding motif in an M2-1 protein of the pneumovirus, wherein the zinc binding motif is mutated relative to wild-type pneumovirus. The mutant pneumoviruses described herein grow to high titer in cell culture, are genetically stable, are attenuated in vitro and in vivo, and are highly immunogenic. Also described herein are vaccines and vaccine compositions comprising the live attenuated mutant pneumoviruses. Vaccine compositions can further comprise a pharmaceutically acceptable carrier, vehicle, excipient, and/or adjuvant. Methods for inducing a protective immune response in a subject against a pneumovirus infection are also described and disclosed. The vaccine compositions and methods described herein can be used to prevent metapneumovirus and respiratory syncytial virus infection in humans, respiratory syncytial virus infection in cattle, avian metapneumovirus infection in various avian species, and pneumonia virus of mice in rodents. |
| FILED | Monday, February 22, 2016 |
| APPL NO | 15/552212 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/23 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 7/045 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2760/18522 (20130101) C12N 2760/18534 (20130101) C12N 2760/18562 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465176 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); Alexis Christine Komor (Pasadena, California) |
| ABSTRACT | Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins of Cas9 and nucleic acid editing enzymes or enzyme domains, e.g., deaminase domains, are provided. In some embodiments, methods for targeted nucleic acid editing are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of Cas9 and nucleic acid editing enzymes or domains, are provided. |
| FILED | Friday, December 12, 2014 |
| APPL NO | 15/103608 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/50 (20130101) A61K 38/465 (20130101) A61K 47/61 (20170801) Peptides C07K 2319/00 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/78 (20130101) C12N 9/6472 (20130101) C12N 15/01 (20130101) C12N 15/102 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 301/00 (20130101) C12Y 301/22 (20130101) C12Y 304/22062 (20130101) C12Y 305/04 (20130101) C12Y 305/04001 (20130101) C12Y 305/04004 (20130101) C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465193 | Chandler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Institute at Nationwide Children's Hospital (Columbia, Ohio) |
| ASSIGNEE(S) | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio) |
| INVENTOR(S) | Dawn Suzan Chandler (Bexley, Ohio); Daniel Forrest Comiskey, Jr. (Columbus, Ohio) |
| ABSTRACT | Compositions and methods for treating cancer in a subject in need thereof are described that includes administering a therapeutically effective amount of an oligonucleotide that inhibits the binding of splicing regulator SRSF1 or SRSF2 to MDM2 exon 4 or 11. |
| FILED | Friday, May 12, 2017 |
| APPL NO | 15/594054 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7088 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1135 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/3521 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465196 | Disney |
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| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Matthew D. Disney (Jupiter, Florida) |
| ABSTRACT | A repeat expansion in C9ORF72 causes frontotemporal dementia and amyotrophic lateral sclerosis (c9FTD/ALS). RNA of the expanded repeat (r(GGGGCC)exp) forms nuclear foci or undergoes repeat-associated non-ATG (RAN) translation producing “c9RAN proteins”. Since neutralizing r(GGGGCC)exp could inhibit these potentially toxic events, we sought to identify small molecule binders of r(GGGGCC)exp. Chemical and enzymatic probing of r(GGGGCC)8 indicate it adopts a hairpin structure in equilibrium with a quadruplex structure. Using this model, bioactive small molecules targeting r(GGGGCC)exp were designed and found to significantly inhibit RAN translation and foci formation in cultured cells expressing r(GGGGCC)66 and neurons trans-differentiated from fibroblasts of repeat expansion carriers. Finally, we show that poly(GP) c9RAN proteins are specifically detected in c9ALS patient cerebrospinal fluid. Our findings highlight r(GGGGCC)exp-binding small molecules as a possible c9FTD/ALS therapeutic, and suggest c9RAN proteins could potentially serve as a pharmacodynamic biomarker to assess efficacy of therapies that target r(GGGGCC)exp. |
| FILED | Wednesday, May 02, 2018 |
| APPL NO | 15/969374 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/7105 (20130101) A61K 38/00 (20130101) A61K 48/00 (20130101) Heterocyclic Compounds C07D 209/14 (20130101) C07D 209/42 (20130101) C07D 471/04 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465227 | Ramasubramanian et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Anand K. Ramasubramanian (San Antonio, Texas); Jose L. Lopez-Ribot (San Antonio, Texas); Anand Srinivasan (San Antonio, Texas) |
| ABSTRACT | The present disclosure provides for microbial testing devices, methods for making microbial testing devices, methods for growing and testing microbial cultures and methods for testing compounds for antimicrobial activity. |
| FILED | Friday, January 23, 2015 |
| APPL NO | 14/603873 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56961 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465234 | Rao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Anjana Rao (La Jolla, California); Mamta Tahiliani (New York, New York); Kian Peng Koh (Jamaica Plain, Massachusetts); Suneet Agarwal (Belmont, Massachusetts); Aravind Iyer (Bethesda, Maryland) |
| ABSTRACT | The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes being capable of converting the cytosine nucleotide 5-methylcytosine into 5-hydroxymethylcytosine by hydroxylation. |
| FILED | Wednesday, October 24, 2018 |
| APPL NO | 16/169801 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0607 (20130101) C12N 5/0637 (20130101) C12N 5/0696 (20130101) C12N 9/0071 (20130101) C12N 15/873 (20130101) C12N 2501/15 (20130101) C12N 2501/70 (20130101) C12N 2501/71 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/606 (20130101) C12N 2501/999 (20130101) C12N 2506/1307 (20130101) C12N 2506/1353 (20130101) C12N 2510/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6886 (20130101) C12Q 2521/531 (20130101) C12Q 2522/10 (20130101) C12Q 2537/164 (20130101) C12Q 2600/154 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5308 (20130101) G01N 33/57426 (20130101) G01N 33/57484 (20130101) G01N 33/57496 (20130101) G01N 2500/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465238 | Ji et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Hanlee P. Ji (Stanford, California); Billy Tsz Cheong Lau (Palo Alto, California); Laura Miotke (Omaha, Nebraska) |
| ABSTRACT | Methods and reagents for performing digital PCR for detection and quantification of mutant alleles and copy number variation are disclosed. In particular, the invention relates to methods using a nonspecific DNA-binding dye, which produces a fluorescent signal that increases in intensity according to the number of base-pairs present in the PCR amplicon product. The method utilizes mutant-specific and wild-type-specific primers having non-complementary “tail” sequences of different lengths. Accordingly, the amplicons for the wild-type and mutant alleles differ in length and can be distinguished based on the difference in the intensities of their fluorescent signals. The methods of the invention can be used to detect rare genetic events, including single nucleotide mutations, alterations of copy number, and deletions or insertions of nucleotides. |
| FILED | Tuesday, December 16, 2014 |
| APPL NO | 15/106288 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6876 (20130101) C12Q 2525/204 (20130101) C12Q 2563/159 (20130101) C12Q 2563/173 (20130101) C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465242 | Phillips et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | John Phillips (Salt Lake City, Utah); William M. Hanson (Salt Lake City, Utah); Jennifer M. Heemstra (Salt Lake City, Utah) |
| ABSTRACT | Systems, devices, and methods for capturing single source-specific biological material from a multi-source aggregate of biological material are disclosed and discussed. A capture system is generated using reversible chain-blocking to make capture substrates having substrate-linked populations of capture molecules specific for molecules of interest. Incubating such capture substrates in the presence of only a single source of biological material facilitates the association of molecules of interest from the same source. Capture substrate-specific barcode sequences coupled to the capture molecules allow multisource aggregate processing and subsequent grouping to retain the source-specific information following downstream processing. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 15/650832 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6876 (20130101) C12Q 2531/113 (20130101) C12Q 2537/143 (20130101) C12Q 2563/149 (20130101) C12Q 2565/519 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465251 | Guda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Kishore Guda (Cleveland, Ohio); Amitabh Chak (University Heights, Ohio); AnnMarie Kieber-Emmons (Cleveland, Ohio) |
| ABSTRACT | A method of analyzing tissue in a subject having or suspected of having cancer includes obtaining an expression profile from a sample of tissue obtained from the subject, wherein the expression profile comprises the level of at least one esophageal adenocarcinoma associated lincRNA selected from the group consisting of linc-PRKD, lincRTL, lincMIA, lincNAV, and lincTMEM. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/568334 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466096 | El-Sherif et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Mahmoud A. El-Sherif (Blue Bell, Pennsylvania); Afshin S. Daryoush (Bryn Mawr, Pennsylvania); Peter A. Lewin (Wyndmoor, Pennsylvania); Rupa Gopinath Minasamudram (Bangalore, India) |
| ABSTRACT | A sensing method is based on using a special fiberoptic probe for detection of acoustic/ultrasound pressure in an immersion medium. The developed system is highly sensitive in detecting ultrasound waves up to 100 MHz, for imaging of micro structures and more. For applications up to 100 MHz, without spatial averaging corrections, the probe tip is modified by reducing the fiber diameter to 7 um or less. Also, to maximize acousto-optic interaction, the probe tip, not just its end face, may be coated with a thin layer of metallic material. This thin film coating satisfies partial transparency of the metallic coating. The coating thickness may range from 2 nm to 10 nm or others depending on the type of the coating material. The probe detects the pressure of acoustic and/or ultrasound waves propagating within an immersion medium, whenever the probe tip is immersed inside the medium, and having a reasonable immersion contact surface. |
| FILED | Monday, April 03, 2017 |
| APPL NO | 15/477247 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/4281 (20130101) A61B 2562/0247 (20130101) A61B 2562/0266 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/004 (20130101) Original (OR) Class Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 11/04 (20130101) G01L 11/025 (20130101) Optical Elements, Systems, or Apparatus G02B 6/262 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466243 | Fan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Zhonghui Hugh Fan (Gainesville, Florida); Jinling Zhang (Gainesville, Florida) |
| ABSTRACT | The subject invention pertains to devices and methods of isolating target cells from a population of cells. The devices comprise of microfluidic channels and aptamers and antibodies attached to the inner surface of the microfluidic channels, wherein the aptamers and the antibodies are capable of specific binding to one or more biomolecules present on the surface of the target cell. The methods of the current invention comprise passing the population of cells through the microfluidic channels to facilitate interaction and capture of the target cells by the aptamers and the antibodies attached to the inner surface of the microfluidic channels, washing to microfluidic channels by a washing solution to remove the cells non-specifically bound to the aptamers and the antibodies attached to the inner surface of the microfluidic channels, releasing the captured target cells from the microfluidic channels, and collecting the released target cells. |
| FILED | Thursday, November 20, 2014 |
| APPL NO | 15/035518 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) B01L 2200/0668 (20130101) B01L 2300/12 (20130101) B01L 2300/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54366 (20130101) G01N 33/57426 (20130101) Original (OR) Class G01N 2333/91205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466248 | Sims |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Peter A. Sims (New York, New York) |
| ABSTRACT | The present invention is methods and assays for identifying single proteins from a sample, without the use of affinity reagents. The methods and assays combine endopeptidase-based component of conventional peptide mapping with single molecule labeling and a microreactor array platform. The invention also includes kits for performing the methods and assays. |
| FILED | Monday, September 22, 2014 |
| APPL NO | 15/024298 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/6818 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466259 | Ke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern Univeristy (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Ke Ke (Oak Ridge, Tennessee); Songwang Hou (Wilmette, Illinois); Ming Zhao (Oak Park, Illinois) |
| ABSTRACT | Provided herein are compositions comprising distinct lipid species in defined ratios and methods of use thereof for the detection of anti-phosphatidylethanolamine (aPE) antibodies and diagnosis of antiphospholipid syndrome (APS). |
| FILED | Friday, November 11, 2016 |
| APPL NO | 15/349368 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/685 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 33/564 (20130101) G01N 2800/32 (20130101) G01N 2800/368 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466316 | Goodwill |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MAGNETIC INSIGHT, INC. (Alameda, California) |
| ASSIGNEE(S) | MAGNETIC INSIGHT, INC. (Alameda, California) |
| INVENTOR(S) | Patrick W. Goodwill (Oakland, California) |
| ABSTRACT | A Magnetic Particle Imaging (MPI) system including a mechanically-rotatable magnet generating a field-free line, where the system is capable of acquiring a plurality of projections at a plurality of rotation angles, and where the projection acquisition includes positioning the field free line at a plurality of positions at the plurality of angles. |
| FILED | Wednesday, July 12, 2017 |
| APPL NO | 15/648421 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0515 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/72 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/10 (20130101) G01R 33/0213 (20130101) G01R 33/1276 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466326 | Sillerud |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC. UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Laurel Sillerud (Albuquerque, New Mexico) |
| ABSTRACT | A method of measuring the concentration of a magnetic material in an object using magnetic resonance imaging comprising administering magnetic material to the object; obtaining a set of T1-weighted and T2-weighted images of the object in order to determine a background magnetic resonance imaging signal intensity and measurements of the background nuclear magnetic relaxation times (T1, T2) of the object without magnetic material; and obtaining a set of T1-weighted and T2-weighted magnetic resonance images of the object with magnetic materials added; measuring effect of magnetic material on the relaxation times; and converting the T1-weighted and T2-weighted images into a set of contrast images which are subtracted from each other to yield a contrast difference image proportional to the concentration of the magnetic material. |
| FILED | Friday, May 13, 2016 |
| APPL NO | 15/574431 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/465 (20130101) G01R 33/5601 (20130101) G01R 33/5602 (20130101) Original (OR) Class G01R 33/5608 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 2209/05 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) G06T 2207/10088 (20130101) G06T 2207/30004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466784 | Cohen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Andrew Cohen (Philadelphia, Pennsylvania); Genevieve Dion (Philadelphia, Pennsylvania); Mark Winter (Wynnewood, Pennsylvania); Eric Wait (Ardmore, Pennsylvania); Michael Koerner (Lansdale, Pennsylvania) |
| ABSTRACT | A wearable device includes: at least one compliant region adapted and configured to be placed over a joint of a subject and at least two flexible but less compliant regions coupled to opposite ends of the compliant region. The device provides a wearable robotic device including a wearable and at least one actuator adapted and configured to move the flexible but less compliant regions relative to each other. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/188386 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/225 (20130101) A61B 5/6806 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/583 (20130101) A61F 5/013 (20130101) A61F 5/0102 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0288 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 13/025 (20130101) Electric Digital Data Processing G06F 3/014 (20130101) Original (OR) Class G06F 3/016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468142 | Abou Shousha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Miami (Miami, Florida) |
| ASSIGNEE(S) | University of Miami (Miami, Florida) |
| INVENTOR(S) | Mohamed Abou Shousha (Pembroke Pines, Florida); Amr Saad Mohamed Elsawy (South Miami, Florida) |
| ABSTRACT | A method of predicting a disease or condition of a cornea or an anterior segment of an eye includes inputting input data into an AI model, processing the input data, and generating a set of scores and outputting a prediction. The input data may be representative of a cornea or anterior segment of an eye. Processing the input data may include processing the data through the plurality of convolutional layers, the fully connected layer, and the output layer. Each score of the set of scores may be generated by a corresponding node in the output layer. The output prediction may be related to the cornea or anterior segment of the eye represented by the input data processed through the AI model. The prediction may be determined by at least one score of the set of scores. |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/047944 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/0025 (20130101) A61B 3/102 (20130101) A61B 3/107 (20130101) A61B 3/117 (20130101) A61B 3/1005 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10024 (20130101) G06T 2207/10101 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30041 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/50 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE47690 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Xuedong Liu (Niwot, Colorado); Gan Zhang (Niwot, Colorado); Daniel Chuen-Fong Chan (Denver, Colorado); Anthony D. Piscopio (Longmont, Colorado) |
| ABSTRACT | The present invention relates to novel hydroxamic acids which are specific histone deacetylase (HDAC) inhibitors and/or TTK/Mps1 kinase inhibitors, including pharmaceutically acceptable salts thereof, which are useful for modulating HDAC and/or TTK/Mps1 kinase activity, pharmaceutical compositions comprising these compounds, and processes for their preparation. |
| FILED | Tuesday, May 01, 2018 |
| APPL NO | 15/968188 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Heterocyclic Compounds C07D 473/16 (20130101) C07D 473/34 (20130101) C07D 487/04 (20130101) C07D 513/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE47691 | Wilton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Western Australia (Crawley, Australia) |
| ASSIGNEE(S) | The University of Western Australia (Crawley, Australia) |
| INVENTOR(S) | Stephen Donald Wilton (Applecross, Australia); Sue Fletcher (Bayswater, Australia); Graham McClorey (Bayswater, Australia) |
| ABSTRACT | An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202. |
| FILED | Monday, July 10, 2017 |
| APPL NO | 15/645842 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/33 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/3233 (20130101) C12N 2310/3341 (20130101) C12N 2310/3519 (20130101) C12N 2320/30 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10463733 | Slocik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secetary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Joseph M. Slocik (Dayton, Ohio); Rajesh R. Naik (Centerville, Ohio); Patrick B. Dennis (Cincinnati, Ohio) |
| ABSTRACT | A method for creating a stable protein/antibody ionic liquid, comprising: (a) cationizing aqueous proteins/antibodies by addition of an excess of a positively-charged crosslinker in the presence of a coupling reagent; (b) purifying the cationized proteins/antibodies; (c) titrating the cationized proteins/antibodies with a corresponding biologically-compatible counter anionic polymer to create at least one protein/antibody cation/anion pair in aqueous solution until the cation/anion pair solution becomes negative by zeta potential measurement; (d) repeatedly dialyzing the protein/antibody cation/anion pair in water to remove excess anionic polymer using at least one molecular weight cutoff 7000 dialysis membrane; (e) lyophilizing the protein/antibody cation/anion pair to remove most of the water, forming a lyophilized solid; and (f) heating the lyophilized solid until a protein/antibody ionic liquid is generated. The antibody may be any desired antibody, and the anion may be any biologically-compatible anion. |
| FILED | Thursday, February 23, 2017 |
| APPL NO | 15/440832 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 39/39591 (20130101) Original (OR) Class A61K 47/48215 (20130101) Peptides C07K 1/10 (20130101) C07K 1/36 (20130101) C07K 16/00 (20130101) C07K 16/34 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464023 | Benton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Porifera, Inc. (Hayward, California) |
| ASSIGNEE(S) | Porifera, Inc. (Hayward, California) |
| INVENTOR(S) | Charles Benton (Berkeley, California); Olgica Bakajin (Berkeley, California) |
| ABSTRACT | An example separation system includes a stack of membrane plate assemblies. An example membrane plate assembly may include membranes bonded to opposite sides of a spacer plate. The spacer plate may include a first opening in fluid communication with a region between the membranes, and a second opening in fluid communication with a region between membrane plate assemblies. Adjacent membrane plate assemblies in the stack may have alternating orientations such that bonding areas for adjacent membranes in the stack may be staggered. Accordingly, two isolated flows may be provided which may be orthogonal from one another. |
| FILED | Monday, March 27, 2017 |
| APPL NO | 15/470757 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/002 (20130101) B01D 63/082 (20130101) Original (OR) Class B01D 63/084 (20130101) B01D 63/085 (20130101) B01D 2313/14 (20130101) B01D 2319/00 (20130101) B01D 2319/02 (20130101) B01D 2319/04 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464065 | Selden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ANDE Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | ANDE Corporation (Waltham, Massachusetts) |
| INVENTOR(S) | Richard F. Selden (Lincoln, Massachusetts); Eugene Tan (Arlington, Massachusetts) |
| ABSTRACT | A self-contained apparatus for isolating nucleic acid, cell lysates and cell suspensions from unprocessed samples apparatus, to be used with an instrument, includes at least one input, and: (i) a macrofluidic component, including a chamber for receiving an unprocessed sample from a collection device and at least one filled liquid purification reagent storage reservoir; and (ii) a microfluidic component in communication with the macrofluidic component through at least one microfluidic element, the microfluidic component further comprising at least one nucleic acid purification matrix; and (iii) at least one interface port to a drive mechanism on the instrument for driving said liquid purification reagent, through the microfluidic element and the nucleic acid purification matrix, wherein the only inputs to the apparatus are through the chamber and the interface port to the drive mechanism. |
| FILED | Monday, October 03, 2016 |
| APPL NO | 15/284023 |
| ART UNIT | 1799 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5029 (20130101) B01L 3/50825 (20130101) B01L 3/502715 (20130101) B01L 3/502753 (20130101) Original (OR) Class B01L 7/52 (20130101) B01L 2200/16 (20130101) B01L 2200/027 (20130101) B01L 2300/087 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) B01L 2300/0887 (20130101) B01L 2400/043 (20130101) B01L 2400/0487 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/101 (20130101) C12N 15/1003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464169 | Fontana et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jake Fontana (Alexandria, Virginia); Steven R. Flom (Alexandria, Virginia); Jawad Naciri (Arlington, Virginia); Banahalli R. Ratna (Alexandria, Virginia) |
| ABSTRACT | Metallic nanorods are welded together in a controllable fashion. A suspension of metallic nanorods coated with an anionic polymer is contracted with linking molecules each comprising a liquid crystal with at least two available carboxylic acid moieties. The nanoparticles to self-assemble into dimers. Irradiation of the dimers with femtosecond radiation forms a metallic junction between them and welds the dimers into fused dimers. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 15/455577 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/121 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/32 (20130101) Original (OR) Class B23K 26/0624 (20151001) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 133/02 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/895 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464666 | Laitenberger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Kevin Laitenberger (Beacon Falls, Connecticut); Stephen V. Poulin (Milford, Connecticut); Erik Byrne (West Haven, Connecticut) |
| ABSTRACT | A swashplate of a blade pitch control assembly is provided including a metal component having one or more interfacing features. The metal component includes a hollow first cylinder having a first flange extending outwardly from a first end thereof and a second flange extending outwardly from a second end thereof. A sidewall extends between the first and second flanges such that a cavity is defined between the first flange, the second flange, and the sidewall. A plurality of connecting members is connected to a portion of the first flange and the second flange and is spaced about a periphery of the first cylinder. A tubular composite component is arranged at least partially within the cavity between adjacent pairs of the connecting members. |
| FILED | Friday, September 18, 2015 |
| APPL NO | 15/527760 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/10 (20130101) B64C 27/605 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464849 | Pope |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Edward J. A. Pope (Westlake Village, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edward J. A. Pope (Westlake Village, California) |
| ABSTRACT | A method for producing a ceramic matrix composite (CMC) material includes impregnating a set of ceramic fibers with a non-fibrous ceramic material, resulting in a precursor matrix, stabilizing the precursor matrix, resulting in a stabilized matrix, and densifying the stabilized matrix using a frequency assisted sintering technology (FAST) process, resulting in a densified CMC material. The resulting densified CMC exhibits superior strength and toughness, relative to prior CMCs. |
| FILED | Wednesday, December 07, 2016 |
| APPL NO | 15/372212 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/571 (20130101) C04B 35/573 (20130101) C04B 35/575 (20130101) C04B 35/645 (20130101) Original (OR) Class C04B 35/806 (20130101) C04B 35/6268 (20130101) C04B 35/62868 (20130101) C04B 35/62873 (20130101) C04B 2235/61 (20130101) C04B 2235/66 (20130101) C04B 2235/77 (20130101) C04B 2235/96 (20130101) C04B 2235/608 (20130101) C04B 2235/614 (20130101) C04B 2235/616 (20130101) C04B 2235/666 (20130101) C04B 2235/3826 (20130101) C04B 2235/5244 (20130101) C04B 2235/5445 (20130101) C04B 2235/6567 (20130101) C04B 2237/32 (20130101) C04B 2237/083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464967 | McCall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Reveragen Biopharma, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | ReveraGen BioPharma, Inc. (Rockville, Maryland) |
| INVENTOR(S) | John M. McCall (Boca Grande, Florida); Eric Hoffman (Kensington, Maryland); Nagaraju (Raju) Kanneboyina (Kensington, Maryland); Jesse Damsker (Washington, District of Columbia) |
| ABSTRACT | The present invention relates to compounds and methods which may be useful as treatments of diseases. |
| FILED | Thursday, November 29, 2012 |
| APPL NO | 14/360384 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/573 (20130101) Steroids C07J 7/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464974 | Hong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Christian Hong (Cincinnati, Ohio); Toru Matsuura (Cincinnati, Ohio) |
| ABSTRACT | Transgenic strains of Neurospora crassa engineered to comprise a synthetic positive feedback loop for a transcriptional activator of cellulase expression such that cellulase production is amplified are disclosed, along with compositions thereof. The transgenic strains are particularly useful in methods for generating purified cellulases, fermentable sugars, and cellulosic ethanol for the efficient production of biofuel from cellulose-containing biomass and waste. |
| FILED | Friday, January 08, 2016 |
| APPL NO | 15/542104 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/37 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) C12N 15/80 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 101/99018 (20130101) C12Y 302/01004 (20130101) C12Y 302/01021 (20130101) C12Y 302/01091 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464985 | Miao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Yubin Miao (Albuquerque, New Mexico); Haixun Guo (Louisville, Kentucky) |
| ABSTRACT | The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states. |
| FILED | Thursday, July 19, 2018 |
| APPL NO | 16/039858 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 51/08 (20130101) A61K 51/086 (20130101) A61K 51/088 (20130101) Peptides C07K 7/54 (20130101) C07K 14/68 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465158 | Ingber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Donald E. Ingber (Boston, Massachusetts); Daniel Levner (Brookline, Massachusetts); Guy Thompson, II (Watertown, Massachusetts); Jose Fernandez-Alcon (Cambridge, Massachusetts); Christopher David Hinojosa (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods interconnect cell culture devices and/or fluidic devices by transferring discrete volumes of fluid between devices. A liquid-handling system collects a volume of fluid from at least one source device and deposits the fluid into at least one destination device. In some embodiments, a liquid-handling robot actuates the movement and operation of a fluid collection device in an automated manner to transfer the fluid between the at least one source device and the at least one destination device. In some cases, the at least one source device and the at least one destination device are cell culture devices. The at least one source device and the at least one destination device may be microfluidic or non-microfluidic devices. In some cases, the cell culture devices may be microfluidic cell culture devices. In further cases, the microfluidic cell culture devices may include organ-chips. |
| FILED | Friday, July 11, 2014 |
| APPL NO | 14/904640 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0293 (20130101) B01L 3/502715 (20130101) B01L 2200/027 (20130101) B01L 2300/0816 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) C12M 23/38 (20130101) C12M 23/58 (20130101) C12M 29/00 (20130101) C12M 29/10 (20130101) Original (OR) Class C12M 29/20 (20130101) C12M 37/04 (20130101) C12M 41/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465176 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); Alexis Christine Komor (Pasadena, California) |
| ABSTRACT | Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins of Cas9 and nucleic acid editing enzymes or enzyme domains, e.g., deaminase domains, are provided. In some embodiments, methods for targeted nucleic acid editing are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of Cas9 and nucleic acid editing enzymes or domains, are provided. |
| FILED | Friday, December 12, 2014 |
| APPL NO | 15/103608 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/50 (20130101) A61K 38/465 (20130101) A61K 47/61 (20170801) Peptides C07K 2319/00 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/78 (20130101) C12N 9/6472 (20130101) C12N 15/01 (20130101) C12N 15/102 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 301/00 (20130101) C12Y 301/22 (20130101) C12Y 304/22062 (20130101) C12Y 305/04 (20130101) C12Y 305/04001 (20130101) C12Y 305/04004 (20130101) C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465187 | Khalil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Ahmad S. Khalil (Lexington, Massachusetts); Albert J. Keung (Raleigh, North Carolina); Minhee Park (Boston, Massachusetts) |
| ABSTRACT | Provided herein are engineered systems and methods for establishing DNA adenine methylation at specific genomic locations and using DNA adenine methylation as an artificial chemical “handle” on the genome. These systems and methods allow for placing the handle on specific genomic locations as well as molecular technologies to bind, spatially spread, and maintain the handle. The systems described herein comprise, in some embodiments, three functional modules that mediate m6A operations: (1) a synthetic initiator module to place m6A at specific genomic sites; (2) a synthetic readout module to program m6A recognition and m6A-dependent transcriptional logic; and (3) propagation module that implements “read-write,” a mechanism proposed to underlie chromatin spreading and epigenetic maintenance across cellular systems. |
| FILED | Tuesday, February 06, 2018 |
| APPL NO | 15/889368 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/1007 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/63 (20130101) C12N 15/102 (20130101) C12N 2310/20 (20170501) Enzymes C12Y 201/01 (20130101) C12Y 301/21003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465233 | Medintz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Igor L. Medintz (Springfield, Virginia); Mario Ancona (Alexandria, Virginia); W. Russ Algar (Vancouver, Canada); Melissa M. Massey (Vancouver, Canada) |
| ABSTRACT | Time-resolved nucleic acids include a long-lifetime FRET donor with an emission lifetime of at least one millisecond (such as a terbium complex), configured as a donor in a first FRET process, and at least one fluorescent dye with an emission lifetime of less than 100 nanoseconds configured as an acceptor in the FRET process. They can be configured as photonic wires, hybridization probes or beacons, and/or systems for computing logical operations. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 15/468767 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) Original (OR) Class C12Q 1/6818 (20130101) C12Q 2563/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465276 | Robinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Joshua Alexander Robinson (Spring Mills, Pennsylvania); Sarah Marie Eichfeld (Bellefonte, Pennsylvania); Aleksander Felipe Piasecki (Blue Bell, Pennsylvania); Brian Michael Bersch (Yardley, Pennsylvania) |
| ABSTRACT | The present invention relates to methods for fabricating a laterally-limited two-dimensional structure through template synthesis. The methods of the invention are useful in forming homogenous and heterogeneous layered materials. The invention also provides structures and devices formed by the method of the present invention and uses thereof. |
| FILED | Monday, January 11, 2016 |
| APPL NO | 14/992160 |
| ART UNIT | 1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/042 (20130101) Original (OR) Class C23C 14/0623 (20130101) C23C 16/042 (20130101) C23C 16/305 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465298 | Ramotowski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Thomas S Ramotowski (Tiverton, Rhode Island) |
| ABSTRACT | A method for improving service life in a connector for joining to a cathodically protected platform includes providing a metallic connector for joining to a cable. A non-conductive coating is provided on the connector proximate the cable. A hydroxide ion diffusion distance is determined that will insure dilution of hydroxide ions to a level that will prevent damage to an encapsulant and non-conductive coating bond on the connector. A polymer encapsulant is molded around the non-conductive coating and the cable to seal the assembled cable in the connector such that the encapsulant and non-conductive coating bond is formed at a greater path distance than the determined hydroxide ion diffusion distance from any hydroxide ion source. |
| FILED | Friday, September 21, 2018 |
| APPL NO | 16/137698 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 13/16 (20130101) Original (OR) Class C23F 13/20 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/72 (20130101) H01R 9/05 (20130101) H01R 13/523 (20130101) H01R 43/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465523 | Devore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Matthew A. Devore (Rocky Hill, Connecticut); Matthew S. Gleiner (Norwalk, Connecticut) |
| ABSTRACT | A gas turbine engine component includes an airfoil that extends from a first side of a platform and a cooling passage that extends through the platform and includes an inlet located on a second opposite side of the platform. The inlet is located axially upstream of the airfoil. |
| FILED | Tuesday, September 15, 2015 |
| APPL NO | 14/854213 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) Original (OR) Class F01D 9/023 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/81 (20130101) F05D 2260/20 (20130101) F05D 2260/201 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465528 | Spangler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Brandon W. Spangler (Vernon, Connecticut); Dominic J. Mongillo, Jr. (West Hartford, Connecticut) |
| ABSTRACT | Turn caps for airfoils of gas turbine engines including cavity sidewalls, a first turn cap divider extending between the cavity sidewalls and defining a turning cavity between the first turn cap divider and the cavity sidewalls, and a second turn cap divider disposed radially inward within the turning cavity. A first turning path is defined between the first turn cap divider and the second turn cap divider and a second turning path is defined radially inward of the second turn cap divider and a merging chamber is formed in the turn cap wherein fluid flows through the first turning path and the second turning path are merged, the merging chamber, the first turning path, and the second turning path forming the turning cavity. |
| FILED | Tuesday, February 07, 2017 |
| APPL NO | 15/426082 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) Original (OR) Class F01D 5/189 (20130101) F01D 9/02 (20130101) F01D 9/065 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/21 (20130101) F05D 2240/81 (20130101) F05D 2240/125 (20130101) F05D 2240/126 (20130101) F05D 2250/185 (20130101) F05D 2260/221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465540 | Carr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Jesse M. Carr (Hartford, Connecticut); Bryan P. Dube (Columbia, Connecticut) |
| ABSTRACT | An airfoil assembly includes at least one airfoil that has a hollow interior. First and second platforms are disposed between the airfoil. At least one tie-spar extends along an axis through the first platform, the hollow interior of the airfoil, and the second platform. There is a thermal expansion difference between a thermal expansion of the tie-spar in the axial direction and the combined thermal expansion of the airfoil and the first and second platform in the axial direction. At least one spacer portion is arranged on the tie-spar. The spacer portion has a thermal expansion in the axial direction that is greater than the thermal expansion difference such that the spacer portion maintains the tie-spar under tension and clamps the first and second platforms on the airfoil. |
| FILED | Tuesday, October 09, 2018 |
| APPL NO | 16/154754 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/284 (20130101) F01D 9/041 (20130101) Original (OR) Class F01D 9/042 (20130101) F01D 25/246 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/51 (20130101) F05D 2230/60 (20130101) F05D 2230/642 (20130101) F05D 2240/12 (20130101) F05D 2240/80 (20130101) F05D 2260/31 (20130101) F05D 2300/5021 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Y02T 50/673 (20130101) Y02T 50/6765 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465542 | Spangler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Brandon W. Spangler (Vernon, Connecticut); Ryan Alan Waite (South Windsor, Connecticut); Steven Bruce Gautschi (Naugatuck, Connecticut); Benjamin F. Hagan (Manchester, Connecticut) |
| ABSTRACT | An airfoil for a gas turbine engine includes pressure and suction side walls joined to one another at leading and trailing edges. The pressure and suction side walls surround an airfoil cavity and provide an exterior airfoil surface. A baffle is arranged in the airfoil cavity and includes a supply hole. Ribs extend between at least one of the pressure and suction side walls into the airfoil cavity to support the baffle relative to the at least one of the pressure and suction side walls. The ribs are configured to provide a serpentine cooling passage between the baffle and at least one of the pressure and suction side walls. The serpentine cooling passage has first and second passes joined by a bend. The ribs form a film cooling cavity between the first and second passes. The supply hole fluidly connects the baffle to the film cooling cavity. Film cooling holes extend through the at least one of the pressure and suction side walls. The film cooling holes are in fluid communication with the film cooling cavity. |
| FILED | Tuesday, September 19, 2017 |
| APPL NO | 15/708603 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) F01D 5/187 (20130101) F01D 9/065 (20130101) Original (OR) Class F01D 25/12 (20130101) F01D 25/14 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/126 (20130101) F05D 2260/20 (20130101) F05D 2260/202 (20130101) F05D 2260/204 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Y02T 50/673 (20130101) Y02T 50/676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465543 | Hagan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| INVENTOR(S) | Benjamin F. Hagan (Manchester, Connecticut); Ryan Alan Waite (Glastonbury, Connecticut); Bryan P. Dube (Columbia, Connecticut); Lane Thornton (Ellington, Connecticut) |
| ABSTRACT | An assembly for a gas turbine engine according to an exemplary aspect of the present disclosure includes, among other things, an airfoil including a radial end, a first passageway having an outlet at the radial end, and a second passageway having an inlet at the radial end. The assembly further includes a cover having at least one turning cavity configured to direct fluid expelled from the outlet of the first passageway into the inlet of the second passageway. |
| FILED | Monday, November 13, 2017 |
| APPL NO | 15/810279 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) F01D 5/186 (20130101) F01D 5/187 (20130101) F01D 5/188 (20130101) F01D 9/041 (20130101) F01D 9/065 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/81 (20130101) F05D 2240/125 (20130101) F05D 2240/307 (20130101) F05D 2250/75 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465559 | Vu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Ky H. Vu (East Hartford, Connecticut); Bryan P. Dube (Columbia, Connecticut); Michael J. Allen (South Windsor, Connecticut) |
| ABSTRACT | A component for a gas turbine engine includes at least one airfoil that has a radially inner end and a radially outer end. A platform has a gas path side that supports the radially outer end of the at least one airfoil and a non-gas path side. A hook is supported by the platform and has an anti-rotation surface that faces in a circumferential direction. A conical surface is spaced axially forward of a base portion of the hook. A triangular base surface intersects the anti-rotation surface and is spaced radially outward from the conical surface. |
| FILED | Wednesday, December 13, 2017 |
| APPL NO | 15/839932 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/042 (20130101) F01D 25/246 (20130101) Original (OR) Class Non-positive-displacement Pumps F04D 29/542 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2250/11 (20130101) F05B 2250/292 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/12 (20130101) F05D 2240/14 (20130101) F05D 2250/11 (20130101) F05D 2250/292 (20130101) F05D 2260/941 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465723 | Ilievski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Filip Ilievski (Santa Clara, California); Xin Chen (Cambridge, Massachusetts); Aaron D. Mazzeo (Duenellen, New Jersey); George M. Whitesides (Newton, Massachusetts); Robert F. Shepherd (Brooktondale, New York); Ramses V. Martinez (Somerville, Massachusetts); Won Jae Choi (Cambridge, Massachusetts); Sen Wai Kwok (Watertown, Massachusetts); Stephen A. Morin (Lincoln, Nebraska); Adam Stokes (Watertown, Massachusetts); Zhihong Nie (Cambridge, Massachusetts) |
| ABSTRACT | A soft robotic device includes a flexible body having a width, a length and a thickness, wherein the thickness is at least 1 mm, the flexible body having at least one channel disposed within the flexible body, the channel defined by upper, lower and side walls, wherein at least one wall is strain limiting; and a pressurizing inlet in fluid communication with the at least one channel, the at least one channel positioned and arranged such that the wall opposite the strain limiting wall preferentially expands when the soft robotic device is pressurized through the inlet. |
| FILED | Monday, October 10, 2016 |
| APPL NO | 15/289436 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) B25J 9/1075 (20130101) B25J 11/00 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 7/06 (20130101) F15B 15/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465726 | Bullard |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Andrew L. Bullard (Manhattan Beach, California) |
| ABSTRACT | A lockable lateral adjuster mechanism comprises a platform with a channel carried by a base. A cam has an eccentric head that is pivotally disposed in the channel. The cam has a stem extending through the channel and into a counter bore in the base. The platform is laterally displaceable with respect to the base as the cam pivots. A countersunk interface is disposed between the eccentric head and the channel. A fastener extends through the cam to the base, and secures the cam, and thus the platform, to the base, and applies an axial load on the countersunk interface along an axis of rotation of the cam. |
| FILED | Tuesday, November 08, 2016 |
| APPL NO | 15/346467 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/0225 (20130101) Original (OR) Class F16B 19/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 403/75 (20150115) Y10T 403/76 (20150115) Y10T 403/1624 (20150115) Y10T 403/7058 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466038 | Kokubun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Daniel N. Kokubun (Waipahu, Hawaii); Sidney Pang (Kaneohe, Hawaii) |
| ABSTRACT | A motion compensation system for a shearography apparatus includes: an adjustable first fold mirror to reflect laser radiation to a receiving aperture of the shearography apparatus during separate pulse periods at corresponding angles of reflection; and corresponding second fold mirrors to reflect the laser radiation from a target surface to the first fold mirror during the respective pulse periods. The shearography apparatus moves with respect to the target surface between the separate pulse periods. The angles of reflection make the laser radiation reflected from the target surface via the respective second fold mirrors appear to the receiving aperture as if the shearography apparatus is stationary with respect to the target surface. In another system, the second fold mirrors are replaced by an adjustable second fold mirror to reflect the laser radiation from the target surface to the first fold mirror during the pulse periods at corresponding second angles of reflection. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/125349 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02098 (20130101) G01B 11/162 (20130101) Original (OR) Class Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 9/0215 (20130101) Optical Elements, Systems, or Apparatus G02B 17/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466068 | Hodjat-Shamami et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Mojtaba Hodjat-Shamami (Atlanta, Georgia); Farrokh Ayazi (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present disclosure can include a method of operating a vibratory gyroscope, the gyroscope comprising a plurality of excitation and readout electrodes, and defined by a first vibratory mode and a second vibratory mode, and the method comprising: introducing an input signal to a first pair of excitation electrodes; multiplying the input signal by scaling coefficients; applying these scaled input signals to a first pair of excitation electrodes; measuring output signals at the first and second pair of readout electrodes that correspond to the first and second vibratory modes respectively; multiplying the output signals by readout scaling coefficients to form scaled output signals, the sums of which provide first and second vibratory mode readout signals; and adjusting the scaling coefficients to maximize the first and minimize the second vibratory mode readout signals. |
| FILED | Monday, January 22, 2018 |
| APPL NO | 15/877099 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5684 (20130101) G01C 19/5776 (20130101) G01C 25/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466102 | Islam |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OMNI MEDSCI, INC. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Omni Medsci, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Mohammed N. Islam (Ann Arbor, Michigan) |
| ABSTRACT | A spectroscopy system includes a light source having an input light source, including semiconductor diodes generating an input beam with a wavelength shorter than 2.5 microns. Cladding-pumped fiber amplifiers receive the input beam and form an amplified optical beam having a spectral width. A nonlinear element broadens the spectral width of the amplified optical beam to 100 nm or more through a nonlinear effect forming an output beam that is pulsed. A filter is coupled to at least one of a lens and a mirror that receives the output beam and delivers the filtered output beam to a sample. A detection system includes detectors configured to receive the output beam reflected or transmitted from the sample. The detection system is configured to use a lock-in technique with the pulsed output beam and the spectroscopy system is adapted to detect chemicals in the sample. |
| FILED | Friday, July 06, 2018 |
| APPL NO | 16/028473 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02091 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 3/108 (20130101) Original (OR) Class G01J 3/0218 (20130101) G01J 3/0245 (20130101) G01J 2003/102 (20130101) G01J 2003/423 (20130101) Optical Elements, Systems, or Apparatus G02B 6/29349 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) G02F 2001/3528 (20130101) G02F 2202/32 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/302 (20130101) H01S 3/1024 (20130101) H01S 3/06725 (20130101) H01S 3/06754 (20130101) H01S 3/094007 (20130101) H01S 3/094069 (20130101) H01S 3/094076 (20130101) H01S 5/0064 (20130101) H01S 5/0085 (20130101) H01S 5/0092 (20130101) H01S 5/146 (20130101) H01S 5/1092 (20130101) H01S 5/4012 (20130101) H01S 2301/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466149 | Weling et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triton Systems, Inc. (Chelmsford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aniruddha Weling (Framingham, Massachusetts); Tyson Lawrence (Cambridge, Massachusetts); Ken Mahmud (Sudbury, Massachusetts); James Burgess (Ringgold, Georgia); Leonid Krasnobaev (Framingham, Massachusetts); Joerg Lahann (Ann Arbor, Michigan) |
| ABSTRACT | A chemical sensing system includes a substrate material, a detector capable of indicating a presence of a target compound, gas, or vapor, and a heater for rapidly releasing compounds, gases and vapors from the substrate material. The substrate material acts to concentrate the compounds, gases, and vapors from a sample area for improved detection by the detector. |
| FILED | Tuesday, August 05, 2014 |
| APPL NO | 14/452398 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) G01N 1/405 (20130101) Original (OR) Class G01N 33/0057 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/25875 (20150115) Y10T 436/173076 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466190 | Ancona et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mario Ancona (Alexandria, Virginia); F. Keith Perkins (Alexandria, Virginia); Arthur W. Snow (Alexandria, Virginia) |
| ABSTRACT | An apparatus and method for producing chemielectric point-sensor systems with increased sensitivity and increased selectivity. The chemielectric sensor system includes a sensor/heater assembly, where the sensor is a chemielectric sensor whose resistance or capacitance changes upon exposure to chemical analytes. The heater functionality applies a programmed sequence of one or more thermal pulses to the sensor to quickly raise its temperature. After each thermal pulse ends the change in resistivity of the sensor is measured. Such data as a function of the pulse time and temperature are recorded and analyzed to determine the chemical composition (selectivity) and concentrations in the ambient vapor by comparison to a library dataset. The sensor operation with fast thermal pulses also allows operation at higher frequencies where the noise is lower and hence sensitivity is improved. |
| FILED | Monday, September 24, 2018 |
| APPL NO | 16/139439 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Separation B01D 53/0462 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) G01N 25/4826 (20130101) Original (OR) Class G01N 30/32 (20130101) G01N 2030/008 (20130101) G01N 2030/326 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466218 | Swager et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy M. Swager (Newton, Massachusetts); Sophie Liu (Cambridge, Massachusetts); Graham Sazama (Chestnut Hill, Massachusetts); Alexander R. Petty (Allston, Massachusetts); Jan M. Schnorr (Boston, Massachusetts) |
| ABSTRACT | A sensor can include a conductive region in electrical communication with at least two electrodes, the conductive region including a conductive material and an alkene-interacting metal complex. |
| FILED | Monday, March 02, 2015 |
| APPL NO | 14/635995 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) G01N 33/0047 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/21 (20150115) Y10T 436/216 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466317 | Sheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Dong Sheng (Princeton, New Jersey); Shuguang Li (Hangzhou, China PRC); Nezih Dural (Bordentown, New Jersey); Michael V. Romalis (Princeton, New Jersey) |
| ABSTRACT | A magnetometer for use with a sample including an atomic vapor includes a cell containing the sample such as a multipass cell including a first mirror element and a second mirror element configured so that an incoming light beam injected into the container will reflect multiple times between the first mirror element and the second mirror element. A polarized pump light source is configured to transmit pump light through the cell and pump the sample. A polarized probe light source configured to transmit probe light through the cell and probe the sample. A detector configured to detect a polarization angle or intensity of the probe light transmitted through the sample. A processor may be configured to calculate a precession frequency of the sample based on a first probe light pulse and a frequency correction based on a second probe light pulse. |
| FILED | Tuesday, June 03, 2014 |
| APPL NO | 14/294578 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466353 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey Rogers (Annandale, Virginia); Katherine Woolfe (Washington, District of Columbia); Matthew David Guild (Alexandria, Virginia); Theodore P. Martin (Springfield, Virginia); Christina Jeanne Naify (Pasadena, California); Charles Alan Rohde (Alexandria, Virginia) |
| ABSTRACT | A leaky-wave antenna for fluid environments includes a waveguide cavity defined by a waveguide wall. The waveguide cavity is filled with a waveguide fluid. The waveguide walls are made of either an anisotropic material that utilize one of orthotropic stiffness of the anisotropic material to control mode conversion, a band gap material to approximate an acoustically rigid boundary, and a combination of the two materials. |
| FILED | Thursday, September 21, 2017 |
| APPL NO | 15/711178 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/28 (20130101) G01S 5/30 (20130101) G01S 15/74 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 13/20 (20130101) Transmission H04B 1/02 (20130101) H04B 13/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466418 | Fanto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Michael L. Fanto (Rome, New York); Paul M. Alsing (Chittenango, New York); Christopher C. Tison (Rome, New York); Stefan F. Preble (Rochester, New York); Jeffrey A. Steidle (Sharon Hill, Pennsylvania) |
| ABSTRACT | The invention provides an apparatus for optical integrated on-chip generation of photon pairs as a building block to create entangled photon states required for quantum information processing. The invention provided a frequency selective optical coupling device which controls the transmission of light by varying the relative dimensions of otherwise symmetrical linear optical waveguides tangential to an annular optical waveguide, thereby controlling the coupling of light between the linear optical waveguides and the annular optical waveguide. Dimensional change of the optical waveguides is achieved by a heated medium in proximity of the optical waveguides and under electronic control. |
| FILED | Wednesday, December 06, 2017 |
| APPL NO | 15/833274 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/12 (20130101) G02B 6/26 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/225 (20130101) G02F 1/3132 (20130101) G02F 2203/055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466430 | Krause |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
| ASSIGNEE(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
| INVENTOR(S) | Joseph P. Krause (Downers Grove, Illinois) |
| ABSTRACT | An apparatus for aligning a fiber optic connector with a detector or an emitter in a housing includes a stationary base mountable on the housing, a mobile stage movable relative to the stationary base, and spring-loaded adjustment screws on the stationary base oriented orthogonally relative to one another to adjust a position of the mobile stage in x and y directions. The stationary base and mobile stage include central openings that allow the adjustment mechanism to be positioned around the fiber optic connector. The stationary base and mobile stage also include lateral slots extending inwardly from their respective peripheral edges to their respective central openings to allow passage of a fiber optic cable when positioning or removing the apparatus. |
| FILED | Thursday, January 10, 2019 |
| APPL NO | 16/244607 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/3897 (20130101) G02B 6/4226 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466649 | Georges, III |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTEGRITY APPLICATIONS INCORPORATED (Carlsbad, California) |
| ASSIGNEE(S) | Centauri, LLC (Chantilly, Virginia) |
| INVENTOR(S) | James A. Georges, III (Brighton, Michigan) |
| ABSTRACT | Systems and methods for simultaneous multi-channel off-axis holography are described. Multi-channel imaging systems can include a light system including a plurality of light sources configured to generate illumination and reference beams at a plurality of wavelengths, an illumination system configured to illuminate a target object with the illumination beams, an optical assembly configured to receive a reflected target beam and condition the target beam for recording at an optical imaging system, and a reference system configured to propagate the reference beams to the optical imaging system. The reference beams are interfered with the target beam at the optical imaging system to create interference patterns, which can be recorded in a collective image having a plurality of side lobes. Holographic information in the side lobes can be combined to generate 3D images having a substantially reduced signal to noise ratio. |
| FILED | Friday, October 27, 2017 |
| APPL NO | 15/796338 |
| ART UNIT | 2485 — Recording and Compression |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/16 (20130101) G03H 1/0443 (20130101) Original (OR) Class G03H 1/0465 (20130101) G03H 2001/045 (20130101) G03H 2001/0445 (20130101) G03H 2001/0452 (20130101) G03H 2001/0469 (20130101) G03H 2210/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466754 | Eastep et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Jonathan M. Eastep (Portland, Oregon); Ilya Sharapov (San Jose, California); Richard J. Greco (West Linn, Oregon); Steve S. Sylvester (Hillsboro, Oregon); David N. Lombard (Rossmoor, California) |
| ABSTRACT | Systems and methods may provide a set of networked computational resources such as nodes that may be arranged in a hierarchy. A hierarchy of performance balancers receives performance samples from the computational resources beneath them and uses the performance samples to conduct a statistical analysis of variations in their performance. In one embodiment, the performance balancers steer power from faster resources to slower resources in order to enhance their performance, including in parallel processing. |
| FILED | Friday, December 26, 2014 |
| APPL NO | 14/583237 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 1/26 (20130101) Original (OR) Class G06F 1/324 (20130101) G06F 1/3203 (20130101) G06F 9/5061 (20130101) G06F 9/5094 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/22 (20180101) Y02D 10/126 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466949 | Chavez |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bell Helicopter Textron Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | BELL HELICOPTER TEXTRON INC. (Fort Worth, Texas) |
| INVENTOR(S) | Jeremy R. Chavez (Colleyville, Texas) |
| ABSTRACT | According to one embodiment, a cockpit display system includes display tiles that together form a single, continuous display screen, a content generation unit configured to generate content instructions that instruct the display screen to display content comprising a plurality of information portions, a display feedback unit, and a content prioritization unit. Each information portion of the plurality of information portions is to be displayed on one or more display tiles of the plurality of display tiles. The display feedback unit is configured to detect a malfunction of one or more malfunctioning display tiles of the plurality of display tiles. The content prioritization unit is configured to instruct the content generation unit to generate updated content instructions. The updated content instructions move at least some of the information portions associated with the one or more malfunctioning display tiles to one or more display tiles that are not experiencing the malfunction. |
| FILED | Thursday, October 08, 2015 |
| APPL NO | 14/878059 |
| ART UNIT | 2692 — Selective Visual Display Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 43/00 (20130101) Electric Digital Data Processing G06F 3/147 (20130101) G06F 3/1423 (20130101) Original (OR) Class Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/20 (20130101) G09G 2300/026 (20130101) G09G 2330/08 (20130101) G09G 2330/12 (20130101) G09G 2380/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10467183 | Fleming, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kermin Fleming, Jr. (Hudson, Massachusetts); Simon C. Steely, Jr. (Hudson, New Hampshire); Kent D. Glossop (Merrimack, New Hampshire) |
| ABSTRACT | Methods and apparatuses relating to pipelined runtime services in spatial arrays are described. In one embodiment, a processor includes processing elements; an interconnect network between the processing elements; a first configuration controller coupled to a first subset of the processing elements; and a second configuration controller coupled to a second, different subset of the processing elements, the first configuration controller and the second configuration controller are to configure the first subset and the second, different subset according to configuration information for a first context, and, for a context switch, the first configuration controller is to configure the first subset according to configuration information for a second context after pending operations of the first context are completed in the first subset and block second context dataflow into the second, different subset's input from the first subset's output until pending operations of the first context are completed in the second, different subset. |
| FILED | Saturday, July 01, 2017 |
| APPL NO | 15/640538 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 15/80 (20130101) G06F 15/825 (20130101) G06F 15/7875 (20130101) G06F 15/7878 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10467544 | Filipp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Stefan Filipp (Zurich, Switzerland); Jay Gambetta (Yorktown Heights, New York) |
| ABSTRACT | Various embodiments provide a coupling mechanism, method of activation and a square lattice. The coupling mechanism comprises two qubits and a tunable coupling qubit that activates an interaction between the two qubits by modulation of a frequency of the tunable coupling qubit. The tunable coupling qubit capacitively couples the two qubits. The tunable coupling qubit is modulated at a difference frequency of the two qubits. The difference frequency may be significantly larger than an anharmonicity of the two qubits. The tunable coupling qubit may be coupled to the two qubits by two electrodes separated by a superconducting quantum interference device (SQUID) loop having two Josephson junctions or by a single electrode with a SQUID loop coupling to ground. The SQUID loop is controlled by an inductively-coupled flux bias line positioned at the center of the tunable coupling qubit. |
| FILED | Thursday, December 31, 2015 |
| APPL NO | 14/985529 |
| ART UNIT | 2125 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 15/82 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10467549 | Cozby et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Richard Cozby (Bel Air, Maryland); Dennis Bushmitch (Somerset, New Jersey); Michael Badger (Ocean Grove, Maryland) |
| ABSTRACT | Various embodiments associated with an interface that displays a visualization are described. In a combat or other environment, a great deal of information can be made available. In addition, this information can be compared against a metric of performance. This metric of performance could be qualitative or quantitative. In a complex environment, a relatively large amount of information can be gathered and it can be beneficial to produce an interface that enables a user to quickly understand the information with specific emphasis on how an entity related to the information is performing against the metric. The interface can include various features, such as time controls that allows for playback of previous information, measures of performance, and a structured tree view that illustrates hierarchical relationships of elements. |
| FILED | Thursday, September 29, 2016 |
| APPL NO | 15/279470 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0484 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468230 | Lavely et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Eugene M. Lavely (Concord, Massachusetts); Adam J. Marcinuk (Lyndeborough, New Hampshire); Amrita V. Masurkar (Burlington, Massachusetts); Paul R. Moffitt (Hollis, New Hampshire); Michael S. Richman (Carlisle, Massachusetts); Jonathan R. Takahashi (Pelham, New Hampshire); Jonathan K. Tong (Cambridge, Massachusetts); Chris L. Willis (Hollis, New Hampshire) |
| ABSTRACT | A system and method for imaging a sample having a complex structure (such as an integrated circuit) implements two modes of operation utilizing a common electron beam generator that produces an electron beam within a chamber. In the first mode, the electron beam interacts directly with the sample, and backscattered electrons, secondary electrons, and backward propagating fluorescent X-rays are measured. In the second mode, the electron beam interrogates the sample via X-rays generated by the electron beam within a target that is positioned between the electron beam generator and the sample. Transmitted X-rays are measured by a detector within the vacuum chamber. The sample is placed on a movable platform to precisely position the sample with respect to the electron beam. Interferometric and/or capacitive sensors are used to measure the position of the sample and movable platform to provide high accuracy metadata for performing high resolution three-dimensional sample reconstruction. |
| FILED | Tuesday, April 10, 2018 |
| APPL NO | 15/949166 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/20 (20130101) H01J 37/28 (20130101) H01J 37/222 (20130101) H01J 37/226 (20130101) H01J 37/244 (20130101) Original (OR) Class H01J 2237/226 (20130101) H01J 2237/2445 (20130101) H01J 2237/2448 (20130101) H01J 2237/2611 (20130101) H01J 2237/2804 (20130101) H01J 2237/2806 (20130101) H01J 2237/2807 (20130101) H01J 2237/20214 (20130101) H01J 2237/20221 (20130101) H01J 2237/20278 (20130101) H01J 2237/20292 (20130101) H01J 2237/24475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468540 | Baril et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America, as represented by the Secretary of the Army (Fort Belvoir, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| INVENTOR(S) | Neil F. Baril (Stafford, Virginia); Sumith V. Bandara (Fairfax Station, Virginia) |
| ABSTRACT | An AlSb lattice matched barrier infrared detector architecture with the AlSb binary barrier layer enables implementation of strain layer superlattice absorbers with higher absorption coefficients for improved quantum efficiency, presents a simplified structure for epitaxial growth, and enables the utilization of bulk InAs0.815Sb0.185 absorber material with a 5.0 μm cutoff for both single and dual color devices. Such an infrared detector is formed by growing the detector material; bottom contact, 1st absorber layer, AlSb barrier, optional graded layer, 2nd absorber layer, top contact, on top of an AlSb lattice matched buffer layer. Epitaxial growth on the AlSb lattice enables the deposition of unstrained bulk InAs0.815Sb0.185 with a 5.0 μm cutoff, as well as InAs/InAs(x)Sb(1-x) superlattice absorbers with a continuously tunable cutoff from mid-wavelength to long-wavelength infrared. |
| FILED | Monday, December 23, 2013 |
| APPL NO | 13/987246 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468668 | Svoboda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia); Binergy Scientific, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Binergy Scientific, Inc. (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Vojtech Svoboda (Atlanta, Georgia); Gleb Yushin (Atlanta, Georgia) |
| ABSTRACT | Disclosed herein are compositions and methods of making such compositions, for making lithium-containing anodes and cathodes. Disclosed are batteries comprising such anodes and/or cathodes, and uses for such batteries. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Monday, August 29, 2016 |
| APPL NO | 15/249810 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/06 (20130101) H01M 4/62 (20130101) H01M 4/133 (20130101) H01M 4/134 (20130101) Original (OR) Class H01M 4/136 (20130101) H01M 4/366 (20130101) H01M 4/405 (20130101) H01M 4/582 (20130101) H01M 4/583 (20130101) H01M 4/621 (20130101) H01M 4/625 (20130101) H01M 4/626 (20130101) H01M 6/36 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468675 | Sutto |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Thomas E. Sutto (Woodbridge, Virginia) |
| ABSTRACT | A method of making a concentrated solution of a metal salt in a non-aqueous solvent system. A product of the process of making a concentrated solution of a metal salt in a non-aqueous solvent system. |
| FILED | Monday, July 10, 2017 |
| APPL NO | 15/645906 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/483 (20130101) Original (OR) Class H01M 4/9016 (20130101) H01M 8/188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468740 | Minev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Zlatko Minev (New Haven, Connecticut); Kyle Serniak (New Haven, Connecticut); Ioan Pop (Karlsruhe, Germany); Yiwen Chu (New Haven, Connecticut); Teresa Brecht (New Haven, Connecticut); Luigi Frunzio (North Haven, Connecticut); Michel Devoret (New Haven, Connecticut); Robert J. Schoelkopf, III (Madison, Connecticut) |
| ABSTRACT | According to some aspects, a quantum mechanical system is provided, comprising a resonator having a plurality of superconducting surfaces and configured to support at least one electromagnetic oscillation mode within a three-dimensional region, wherein the plurality of superconducting surfaces include a first superconducting surface that defines a first plane, and a physical qubit comprising at least one planar component that is planar within the first plane and borders the three-dimensional region. |
| FILED | Friday, February 26, 2016 |
| APPL NO | 15/553012 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/02 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468758 | Ozdemir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Virtual EM Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | VIRTUAL EM INC. (Ann Arbor, Michigan) |
| INVENTOR(S) | Tayfun Ozdemir (Ann Arbor, Michigan); Christopher N. Davis (Ann Arbor, Michigan) |
| ABSTRACT | An aircraft includes a fuselage assembly including a first elongated structural member formed of electrically conductive material, at least one wing assembly including a second structural member formed of electrically conductive material, at least one horizontal stabilizer assembly including a third structural member formed of electrically conductive material, and at least one vertical stabilizer assembly including a fourth structural member formed of electrically conductive material. The wing assembly, the horizontal stabilizer, and the vertical stabilizer are each interconnected with the fuselage assembly in a flight configuration normal to the fuselage. The first, second, third and fourth structural members are electrically insulated from one another. An electronic communication device within the aircraft is configurable for selective electrical interconnection of two or more of said structural members to form a dipole or monopole type transmitting/receiving antenna. |
| FILED | Monday, May 07, 2018 |
| APPL NO | 15/973448 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/28 (20130101) Original (OR) Class H01Q 1/521 (20130101) H01Q 9/28 (20130101) H01Q 9/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468782 | Steinbrecher |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Donald H Steinbrecher (Brookline, Massachusetts) |
| ABSTRACT | A method is provided for determining instantaneous polarization of multiple electromagnetic transmissions. A segmented aperture system determines a direction of arrival of a transmission based on port coordinates and the geometric relationship of the segments. The ports receive at least two orthogonal polarizations that characterize the incoming signals. Two angles are calculated by a simultaneous solution of two phase difference measurements to determine the direction of arrival. A mean direction of arrival solution is obtained by averaging solution estimates that are obtained by repeating the direction of arrival determination. |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 16/384971 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/0892 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/32 (20130101) G01S 3/74 (20130101) Antennas, i.e Radio Aerials H01Q 17/00 (20130101) H01Q 21/061 (20130101) Original (OR) Class H01Q 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468890 | Phipps et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Alex G. Phipps (San Diego, California); Lewis Hsu (San Diego, California); Maxwell M. Kerber (San Diego, California); David B. Chadwick (San Diego, California); Y. Meriah Arias-Thode (San Diego, California); Jeffrey Kagan (San Diego, California) |
| ABSTRACT | A system comprising a series of at least two benthic microbial fuel cells (BMFC), wherein each BMFC comprises an anode electrically connected to a cathode, and wherein for each BMFC there is a first and second comparator configured to monitor BMFC voltage to determine if the voltage falls below one of two present thresholds. The output of the first comparator is electrically connected to the BMFC via a switch and the output of the second comparator is electrically connected to a pulse width monitor (PWM) block via a switch. A DC/DC converter is electrically coupled to each BMFC and configured to transfer energy stored in each BMFC to a battery, wherein the DC/DC converter is driven by the PWM block. |
| FILED | Tuesday, February 28, 2017 |
| APPL NO | 15/444722 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/86 (20130101) H01M 8/16 (20130101) H01M 8/04552 (20130101) H01M 2004/027 (20130101) H01M 2004/028 (20130101) H01M 2250/10 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0008 (20130101) Original (OR) Class H02J 7/0047 (20130101) H02J 7/0052 (20130101) H02J 7/0093 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/527 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468955 | Ricci et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAUNCHPOINT TECHNOLOGIES, INC. (Goleta, California) |
| ASSIGNEE(S) | LAUNCHPOINT TECHNOLOGIES, INC. (Goleta, California) |
| INVENTOR(S) | Michael Richard Ricci (Camarillo, California); Jonathan Gordon Sugar (Ventura, California); Bradley Evan Paden (Goleta, California); David Brian Paden (Goleta, California) |
| ABSTRACT | An axial flux brushless permanent magnet electrical machine having a stator and at least one rotor. The rotor includes a Halbach array of magnets with at least four magnets per magnetic cycle. The rotor magnets are contained within pockets in the rotor. The pockets are formed with magnet pocket walls being radial walls, active surface walls, and/or inactive surface walls where the walls retain the magnets within the pockets. |
| FILED | Wednesday, October 24, 2018 |
| APPL NO | 16/169043 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 1/30 (20130101) H02K 1/2793 (20130101) H02K 21/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10469125 | Robertson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Andrew Robertson (Washington, District of Columbia); Joseph A. Molnar (Washington, District of Columbia); Frank Fu (Washington, District of Columbia) |
| ABSTRACT | A method of transmitting a message using a slow hopping anti-jam waveform, includes generating a sequence with a cryptographic hash function; transmitting, for a predetermined dwell time, a first portion of the message on a first channel having a first baseline frequency; choosing a second channel having a second baseline frequency based on the generated sequence, the second baseline frequency being offset from the first baseline frequency; and transmitting, for the predetermined dwell time, a second portion of the message on the second channel having the second baseline frequency; wherein the two transmitting steps occur sequentially. |
| FILED | Wednesday, June 08, 2016 |
| APPL NO | 15/176739 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Transmission H04B 1/692 (20130101) Original (OR) Class H04B 1/707 (20130101) H04B 1/713 (20130101) H04B 1/7103 (20130101) H04B 2201/71361 (20130101) Multiplex Communication H04J 13/0062 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/12 (20130101) H04L 9/3236 (20130101) H04L 9/3247 (20130101) H04L 9/3297 (20130101) H04L 63/18 (20130101) H04L 63/1466 (20130101) H04L 69/28 (20130101) H04L 2209/80 (20130101) Wireless Communication Networks H04W 12/06 (20130101) H04W 12/12 (20130101) H04W 12/00502 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10469347 | Eastep et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Jonathan M. Eastep (Portland, Oregon); Eric R. Borch (Fort Collins, Colorado) |
| ABSTRACT | Systems, apparatuses and methods may provide for a plurality of node-level agents, wherein each node-level agent aggregates network statistics information from a plurality of probes associated with a communications interface. Additionally, one or more job-level agents may be communicatively coupled to the plurality of node-level agents, wherein each job-level agent aggregates network statistics information from two or more of the node-level agents. Moreover, a system-level agent may be communicatively coupled to the job-level agent(s). The system-level agent may generate a power model based on aggregated network statistics information from the job-level agent(s) and propagate the power model to the node-level agents via the job-level agent(s). |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/081444 |
| ART UNIT | 2445 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/142 (20130101) H04L 43/08 (20130101) Original (OR) Class H04L 43/12 (20130101) H04L 43/045 (20130101) H04L 47/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10469397 | Fleming et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kermin Fleming (Hudson, Massachusetts); Kent D. Glossop (Merrimack, New Hampshire); Simon C. Steely, Jr. (Hudson, New Hampshire) |
| ABSTRACT | Systems, methods, and apparatuses relating to configurable network-based dataflow operator circuits are described. In one embodiment, a processor includes a spatial array of processing elements, and a packet switched communications network to route data within the spatial array between processing elements according to a dataflow graph to perform a first dataflow operation of the dataflow graph, wherein the packet switched communications network further comprises a plurality of network dataflow endpoint circuits to perform a second dataflow operation of the dataflow graph. |
| FILED | Saturday, July 01, 2017 |
| APPL NO | 15/640540 |
| ART UNIT | 2463 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/72 (20130101) H04L 47/10 (20130101) H04L 47/62 (20130101) Original (OR) Class H04L 49/254 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10469486 | Baras et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND (College Park, Maryland) |
| INVENTOR(S) | John S. Baras (Potomac, Maryland); Vladimir Iankov Ivanov (Hyattsville, Maryland) |
| ABSTRACT | Methods and apparatuses for authenticating communication devices and securely transmitting and/or receiving encrypted voice and data information. A biometric scanner, for example a fingerprint scanner, is utilized for authenticating the communication device and for generating the encryption key. The fingerprint scanner can be an area or swipe type of scanner is registered to a particular user and has unique intrinsic characteristics (the scanner pattern) that are permanent over time and can identify the scanner even among scanners of the same manufacturer and model. The unique scanner pattern of the scanner generates a unique encryption key that cannot be reproduced using another fingerprint scanner. |
| FILED | Saturday, April 08, 2017 |
| APPL NO | 15/482759 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00006 (20130101) G06K 9/527 (20130101) G06K 9/6277 (20130101) G06K 2009/00583 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) H04L 9/3231 (20130101) H04L 63/0435 (20130101) H04L 63/0861 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10469588 | Gorshechnikov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Neurala, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Neurala, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Anatoly Gorshechnikov (Newton, Massachusetts); Massimiliano Versace (South Boston, Massachusetts); Heather Ames Versace (South Boston, Massachusetts); Gennady Livitz (Belmont, Massachusetts) |
| ABSTRACT | The system and methods disclosed herein include a runtime architecture that takes a nonspecific set of systems of differential equations, distributes them across the network, and iteratively integrates them through time with a possibility to output the results on every iteration. Embodiments of the disclosed system may be used for neural computation or any other suitable application. Embodiments can be used as a standalone engine or as part of another computational system for massively parallel numerical integration of a data-driven dynamical system. |
| FILED | Friday, November 20, 2015 |
| APPL NO | 14/947337 |
| ART UNIT | 2442 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 9/546 (20130101) G06F 9/5066 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0454 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/045 (20130101) H04L 67/10 (20130101) H04L 67/125 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10469831 | Debevec et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Paul E. Debevec (Culver City, California); Graham Leslie Fyffe (Los Angeles, California) |
| ABSTRACT | A system may almost instantly capturing high-resolution geometry and reflectance data of a portion of a human subject. The system may include multiple cameras, each oriented to controllably capture an image of the portion of the human subject from a different location in space; multiple lights, each oriented to controllably illuminate the portion of the human subject from a location in space significantly different than the location in space of the other lights; and a controller. The controller may divide the cameras into subgroups with each subgroup of cameras containing at least one camera and with each camera belonging to only one of the subgroups; cause each subgroup of cameras to sequentially capture a single image of the portion of the human subject; and cause at least one of the lights to light while each subgroup of cameras captures a single image of the portion of the human subject. The system may include an image processing system that generates the high resolution geometry and reflectance data based on only one image from each camera. A polarizing optical element may be between each camera and the portion of the human subject. A polarizer filter may be between each light and the portion of the human subject. A controller may cause all of the cameras to simultaneously capture a single image of the portion of the human subject while the portion of the human subject is illuminated by all of the lights. The specular reflections from the portion of the human subject that are captured by one of the cameras may have a color distribution across the portion of the human subject that is different than the specular reflections from the portion of the human subject that are captured by another of the cameras. |
| FILED | Friday, March 06, 2015 |
| APPL NO | 14/640813 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00221 (20130101) Image Data Processing or Generation, in General G06T 15/04 (20130101) G06T 2207/10012 (20130101) G06T 2215/12 (20130101) Pictorial Communication, e.g Television H04N 13/243 (20180501) Original (OR) Class H04N 13/254 (20180501) H04N 13/257 (20180501) H04N 13/296 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10470287 | Kobernik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PHOENIX LLC (Monona, Wisconsin) |
| ASSIGNEE(S) | PHOENIX LLC (Monona, Wisconsin) |
| INVENTOR(S) | Arne Kobernik (Monona, Wisconsin); Carl Sherven (Monona, Wisconsin); Casey Lamers (Monona, Wisconsin); Chris Seyfert (Monona, Wisconsin); Evan Sengbusch (Monona, Wisconsin); Gabriel Becerra (Monona, Wisconsin); Jin Lee (Monona, Wisconsin); Logan Campbell (Monona, Wisconsin); Mark Thomas (Monona, Wisconsin); Michael Taylor (Monona, Wisconsin); Preston Barrows (Monona, Wisconsin); Ross Radel (Monona, Wisconsin); Tye Gribb (Monona, Wisconsin) |
| ABSTRACT | Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196720 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10470288 | Kobernik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PHOENIX LLC (Monona, Wisconsin) |
| ASSIGNEE(S) | PHOENIX LLC (Monona, Wisconsin) |
| INVENTOR(S) | Arne Kobernik (Monona, Wisconsin); Carl Sherven (Monona, Wisconsin); Casey Lamers (Monona, Wisconsin); Chris Seyfert (Monona, Wisconsin); Evan Sengbusch (Monona, Wisconsin); Gabriel Becerra (Monona, Wisconsin); Jin Lee (Monona, Wisconsin); Logan Campbell (Monona, Wisconsin); Mark Thomas (Monona, Wisconsin); Michael Taylor (Monona, Wisconsin); Preston Barrows (Monona, Wisconsin); Ross Radel (Monona, Wisconsin); Tye Gribb (Monona, Wisconsin) |
| ABSTRACT | Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196556 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/08 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/54 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE47690 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Xuedong Liu (Niwot, Colorado); Gan Zhang (Niwot, Colorado); Daniel Chuen-Fong Chan (Denver, Colorado); Anthony D. Piscopio (Longmont, Colorado) |
| ABSTRACT | The present invention relates to novel hydroxamic acids which are specific histone deacetylase (HDAC) inhibitors and/or TTK/Mps1 kinase inhibitors, including pharmaceutically acceptable salts thereof, which are useful for modulating HDAC and/or TTK/Mps1 kinase activity, pharmaceutical compositions comprising these compounds, and processes for their preparation. |
| FILED | Tuesday, May 01, 2018 |
| APPL NO | 15/968188 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Heterocyclic Compounds C07D 473/16 (20130101) C07D 473/34 (20130101) C07D 487/04 (20130101) C07D 513/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10463044 | Gokel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George W. Gokel (St. Louis, Missouri); Michael R. Gokel (St. Louis, Missouri); Saeedeh Negin (St. Louis, Missouri); Mohit B. Patel (St. Louis, Missouri) |
| ABSTRACT | Methods and compositions are provided for increasing or enhancing the efficacy of antibiotics, such as by increasing antimicrobial activity, against a variety of microbes by co-administration with synthetic amphiphiles, including lariat ethers and hydraphiles. Methods and compositions for overcoming antibiotic resistance are also provided. |
| FILED | Friday, June 17, 2016 |
| APPL NO | 15/186070 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/72 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 31/65 (20130101) A61K 31/165 (20130101) A61K 31/165 (20130101) A61K 31/395 (20130101) A61K 31/496 (20130101) A61K 38/16 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463293 | Maharbiz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Michel Maharbiz (El Cerrito, California); Vivek Subramanian (Orinda, California); Ana Claudia Arias (Lafayette, California); Sarah Swisher (El Cerrito, California); Amy Liao (Berkeley, California); Monica Lin (Berkeley, California); Felippe Pavinatto (Albany, California); Yasser Khan (Berkeley, California); Daniel Cohen (Berkeley, California); Elisabeth Leeflang (San Francisco, California); Shuvo Roy (San Francisco, California); Michael Harrison (San Francisco, California); David Young (Mill Valley, California) |
| ABSTRACT | Methods and apparatus for real-time, quantifiable monitoring of high-risk areas of biological tissue are described. The methods and apparatus use impedance spectroscopy to detect subtle changes in tissue health. |
| FILED | Wednesday, December 14, 2016 |
| APPL NO | 15/379220 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/053 (20130101) A61B 5/445 (20130101) Original (OR) Class A61B 5/7278 (20130101) A61B 2562/04 (20130101) A61B 2562/046 (20130101) A61B 2562/125 (20130101) A61B 2562/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463560 | Deshpande et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Ashish Deshpande (Austin, Texas); Bongsu Kim (Austin, Texas) |
| ABSTRACT | The present disclosure includes a robotic exoskeleton comprising a back portion providing at least two degrees of freedom, two shoulder portions, each shoulder portion providing at least five degrees of freedom, two elbow portions, each elbow portion providing at least one degree of freedom, and two forearm portions, each forearm portion providing at least one degree of freedom. The present disclosure may also relate to associated robotic forearm joints and robotic shoulder joints. |
| FILED | Monday, March 28, 2016 |
| APPL NO | 15/082783 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) A61F 2/76 (20130101) A61F 2/78 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/02 (20130101) Original (OR) Class A61H 1/0274 (20130101) A61H 1/0277 (20130101) A61H 1/0281 (20130101) A61H 2201/165 (20130101) A61H 2201/1207 (20130101) A61H 2201/1215 (20130101) A61H 2201/1454 (20130101) A61H 2201/1481 (20130101) A61H 2201/1614 (20130101) A61H 2201/1616 (20130101) A61H 2201/1619 (20130101) A61H 2201/1621 (20130101) A61H 2201/1638 (20130101) A61H 2201/1676 (20130101) A61H 2201/5058 (20130101) A61H 2201/5061 (20130101) A61H 2201/5064 (20130101) A61H 2201/5069 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463609 | Rangaramanujam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kannan Rangaramanujam (Novi, Michigan); Raymond Iezzi (Troy, Michigan); Bharath Rajaguru (Detroit, Michigan); Sujatha Kannan (Novi, Michigan) |
| ASSIGNEE(S) | WAYNE STATE UNIVERSITY (Detroit, Michigan) |
| INVENTOR(S) | Kannan Rangaramanujam (Novi, Michigan); Raymond Iezzi (Troy, Michigan); Bharath Rajaguru (Detroit, Michigan); Sujatha Kannan (Novi, Michigan) |
| ABSTRACT | Dendrimer-based compositions and methods are provided, that are useful for administering pharmaceutical compositions to target cells and tissues for treatment of ocular diseases including macular degeneration, diabetic retinopathy, and retinitis pigmentosa. |
| FILED | Monday, October 06, 2008 |
| APPL NO | 12/681516 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) Original (OR) Class A61K 9/0051 (20130101) A61K 9/1647 (20130101) A61K 9/5031 (20130101) A61K 9/5153 (20130101) A61K 31/58 (20130101) A61K 31/65 (20130101) A61K 31/7088 (20130101) A61K 47/595 (20170801) A61K 47/6935 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/028 (20130101) C08G 83/003 (20130101) Compositions of Macromolecular Compounds C08L 79/02 (20130101) C08L 101/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463631 | Jabbarzadeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Ehsan Jabbarzadeh (Columbia, South Carolina); Sara Eslambolchimoghada (Columbia, South Carolina) |
| ABSTRACT | Methods and compositions are described for use in encouraging angiogenesis and skin healing as may be utilized in wound treatment as well as in encouragement of angiogenesis in disease. Compositions include an effective amount of a natural pimarane diterpenoid extract of Hymenocrater elegans, or a derivative, analogue, or homolog thereof. Compounds based upon this natural extract have been found to be highly effective in vascular formation and skin closure while exhibiting low toxicity. |
| FILED | Monday, June 11, 2018 |
| APPL NO | 16/004576 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/047 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10463649 — Inhibitors of Mc1-1 as drugs to overcome resistance to BRAF inhibitors and MEK inhibitors
| US 10463649 | Srivastava et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | Texas Tech University System (Lubbock, Texas) |
| INVENTOR(S) | Sanjay K. Srivastava (Amarillo, Texas); Neel M. Fofaria (Amarillo, Texas) |
| ABSTRACT | The present invention includes compositions and methods for inhibiting MCL-1, including novel inhibitors of MCL-1, and compositions and methods for treating a subject with cancer that is refractory to one or more MAPK pathway protein inhibitors. |
| FILED | Monday, June 06, 2016 |
| APPL NO | 15/580991 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/47 (20130101) A61K 31/47 (20130101) A61K 31/50 (20130101) A61K 31/50 (20130101) A61K 31/54 (20130101) A61K 31/54 (20130101) A61K 31/165 (20130101) A61K 31/165 (20130101) A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/341 (20130101) A61K 31/405 (20130101) A61K 31/423 (20130101) A61K 31/433 (20130101) A61K 31/433 (20130101) A61K 31/437 (20130101) A61K 31/444 (20130101) A61K 31/445 (20130101) A61K 31/445 (20130101) A61K 31/495 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/501 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/538 (20130101) A61K 31/538 (20130101) A61K 31/541 (20130101) A61K 31/4025 (20130101) A61K 31/4025 (20130101) A61K 31/4164 (20130101) A61K 31/4164 (20130101) A61K 31/4178 (20130101) A61K 31/4184 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4196 (20130101) A61K 31/4196 (20130101) A61K 31/4245 (20130101) A61K 31/4436 (20130101) A61K 31/4436 (20130101) A61K 31/4439 (20130101) A61K 31/4525 (20130101) A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 31/4965 (20130101) A61K 31/5375 (20130101) A61K 31/5375 (20130101) A61K 31/5377 (20130101) A61K 31/5415 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 233/87 (20130101) C07C 237/00 (20130101) C07C 237/52 (20130101) Heterocyclic Compounds C07D 207/337 (20130101) C07D 209/08 (20130101) C07D 209/42 (20130101) C07D 211/34 (20130101) C07D 215/48 (20130101) C07D 217/06 (20130101) C07D 233/60 (20130101) C07D 235/10 (20130101) C07D 235/12 (20130101) C07D 235/16 (20130101) C07D 235/28 (20130101) C07D 249/12 (20130101) C07D 263/34 (20130101) C07D 265/36 (20130101) C07D 279/02 (20130101) C07D 295/108 (20130101) C07D 307/54 (20130101) C07D 317/60 (20130101) C07D 401/06 (20130101) C07D 403/06 (20130101) C07D 403/14 (20130101) C07D 405/06 (20130101) C07D 409/14 (20130101) C07D 413/06 (20130101) C07D 417/12 (20130101) C07D 487/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 2333/4703 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463688 | Gellman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Samuel H. Gellman (Madison, Wisconsin); Runhui Liu (Madison, Wisconsin); Bernard Weisblum (Madison, Wisconsin); Shonna M. McBride (Atlanta, Georgia) |
| ABSTRACT | A method and corresponding composition to inhibit outgrowth of C. difficile spores and/or to inhibit growth of C. difficile vegetative cells in a mammal in which an amount of a nylon-3 polymer or nylon-3 copolymer or a pharmaceutically suitable salt thereof is administered to the subject. |
| FILED | Thursday, June 30, 2016 |
| APPL NO | 15/198588 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/787 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10463752 | Montclare et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Jin Kim Montclare (New York, New York); Joseph Frezzo (Brooklyn, New York); Min Dai (New York, New York); Raymond Chen (Whitestone, New York) |
| ABSTRACT | Protein polymer-gold nanoparticles, compositions comprising protein polymer-gold nanoparticles, and uses of protein polymer-gold nanoparticles. A protein polymer-gold nanoparticle comprises a gold core and a plurality of protein polymer molecules coordinated to the gold core via a poly-histidine tag present on each protein polymer molecule. A protein polymer molecule comprises one or more elastin-like polypeptide domain and a coiled-coil region of Cartilage Oligomeric Matrix Protein domain or a variant thereof. For example, the protein polymer-gold nanoparticles can be used in methods of small molecule delivery to an individual. |
| FILED | Friday, January 06, 2017 |
| APPL NO | 15/400342 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/1878 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465033 | Urban |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Clemson University (Clemson, South Carolina) |
| ASSIGNEE(S) | Clemson University Research Foundation (Clemson, South Carolina) |
| INVENTOR(S) | Marek W. Urban (Clemson, South Carolina) |
| ABSTRACT | Single-step synthesis processes for production of ultrahigh molecular weight block copolymers are described. The ultrahigh molecular weight copolymers can have a molecular weight of about 106 or greater and can be formed within a few hours in a surfactant-free environment. The formation process is controlled by initiator-starvation conditions in a sequential polymerization of monomers exhibiting different solubility in the solvent. |
| FILED | Thursday, November 09, 2017 |
| APPL NO | 15/807712 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 212/08 (20130101) C08F 220/14 (20130101) C08F 220/24 (20130101) C08F 220/34 (20130101) C08F 220/34 (20130101) C08F 293/00 (20130101) C08F 297/026 (20130101) Original (OR) Class C08F 2220/1825 (20130101) C08F 2500/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465043 | Tessonnier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation (Ames, Iowa) |
| INVENTOR(S) | Jean-Philippe Tessonnier (Ames, Iowa); John Edward Matthiesen (Ames, Iowa); Toni Pfennig (Ames, Iowa); Brent Shanks (Ames, Iowa); Jack M. Carraher (Ames, Iowa) |
| ABSTRACT | Various embodiments disclosed relate to electrochemical isomerization of muconic acid. In various embodiments, the present invention provides a method to prepare trans,trans-muconic acid. The method can include passing current through a catalytic cathode in a reactor including an aqueous acidic solution including cis,trans-muconic acid, a supporting electrolyte, and an anode, so as to isomerize the cis,trans-muconic acid to yield a product including trans trans-muconic acid. |
| FILED | Thursday, November 10, 2016 |
| APPL NO | 15/348122 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 2219/0809 (20130101) B01J 2219/0877 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/09 (20130101) Acyclic or Carbocyclic Compounds C07C 51/347 (20130101) C07C 51/353 (20130101) C07C 51/377 (20130101) C07C 2601/14 (20170501) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/78 (20130101) Original (OR) Class C08G 63/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465087 | Gopalan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Padma Gopalan (Madison, Wisconsin); Daniel Patrick Sweat (Madison, Wisconsin); Myungwoong Kim (Madison, Wisconsin) |
| ABSTRACT | Crosslinkable random copolymers comprising atom transfer radical polymerization (ATRP) initiators and crosslinked copolymer films formed from the copolymers are provided. The random copolymers, which are polymerized from one or more alkyl halide functional inimers and one or more monomers having a crosslinkable functionality, are characterized by pendant ATRP initiating groups and pendant crosslinkable groups. |
| FILED | Thursday, January 19, 2017 |
| APPL NO | 15/410103 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/007 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/0149 (20130101) B81C 2201/0156 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 12/16 (20130101) C08F 14/16 (20130101) C08F 20/22 (20130101) C08F 20/32 (20130101) C08F 214/16 (20130101) C08F 220/22 (20130101) C08F 220/32 (20130101) C08F 293/005 (20130101) C08F 2438/01 (20130101) C08F 2438/03 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 5/18 (20130101) C08J 2327/10 (20130101) C08J 2333/14 (20130101) Compositions of Macromolecular Compounds C08L 2312/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 127/10 (20130101) C09D 133/08 (20130101) Original (OR) Class C09D 133/14 (20130101) C09D 133/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465154 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yajia Yang (Los Angeles, California); Yufei Mao (Los Angeles, California); Pei-Yu E. Chiou (Los Angeles, California); Chi On Chui (Encino, California) |
| ABSTRACT | A novel Self-Locking Optoelectronic Tweezers (SLOT) for single microparticle manipulation across a large area is provided. DEP forces generated from ring-shape lateral phototransistors are utilized for locking single microparticles or cells in the dark state. The locked microparticles or cells can be selectively released by optically deactivating these locking sites. |
| FILED | Friday, August 14, 2015 |
| APPL NO | 15/501428 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 2200/0668 (20130101) B01L 2400/0454 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Apparatus for Enzymology or Microbiology; C12M 1/42 (20130101) Original (OR) Class C12M 3/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 2035/1046 (20130101) Optical Elements, Systems, or Apparatus G02B 21/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465187 | Khalil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Ahmad S. Khalil (Lexington, Massachusetts); Albert J. Keung (Raleigh, North Carolina); Minhee Park (Boston, Massachusetts) |
| ABSTRACT | Provided herein are engineered systems and methods for establishing DNA adenine methylation at specific genomic locations and using DNA adenine methylation as an artificial chemical “handle” on the genome. These systems and methods allow for placing the handle on specific genomic locations as well as molecular technologies to bind, spatially spread, and maintain the handle. The systems described herein comprise, in some embodiments, three functional modules that mediate m6A operations: (1) a synthetic initiator module to place m6A at specific genomic sites; (2) a synthetic readout module to program m6A recognition and m6A-dependent transcriptional logic; and (3) propagation module that implements “read-write,” a mechanism proposed to underlie chromatin spreading and epigenetic maintenance across cellular systems. |
| FILED | Tuesday, February 06, 2018 |
| APPL NO | 15/889368 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/1007 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/63 (20130101) C12N 15/102 (20130101) C12N 2310/20 (20170501) Enzymes C12Y 201/01 (20130101) C12Y 301/21003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465212 | San et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Ka-Yiu San (Houston, Texas); Mai Li (Houston, Texas); Xiujun Zhang (Houston, Texas) |
| ABSTRACT | There is provided a recombinant bacterium comprising at least one overexpressed acyl-ACP thioesterase gene, and wherein at least one gene from the tricarboxylic acid cycle or glycolysis or both is inactivated. There is also provided a method for producing fatty acids, said method comprising culturing bacteria comprising at least one overexpressed acyl-ACP thioesterase gene in a growth medium in a container having walls; allowing said bacteria to secrete fatty acids; and collecting said fatty acids. Acid supplementation is also shown to increase productivity. |
| FILED | Friday, March 18, 2016 |
| APPL NO | 15/073641 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/2442 (20130101) C12N 15/52 (20130101) C12N 15/70 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class Enzymes C12Y 301/02014 (20130101) C12Y 302/01014 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465242 | Phillips et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | John Phillips (Salt Lake City, Utah); William M. Hanson (Salt Lake City, Utah); Jennifer M. Heemstra (Salt Lake City, Utah) |
| ABSTRACT | Systems, devices, and methods for capturing single source-specific biological material from a multi-source aggregate of biological material are disclosed and discussed. A capture system is generated using reversible chain-blocking to make capture substrates having substrate-linked populations of capture molecules specific for molecules of interest. Incubating such capture substrates in the presence of only a single source of biological material facilitates the association of molecules of interest from the same source. Capture substrate-specific barcode sequences coupled to the capture molecules allow multisource aggregate processing and subsequent grouping to retain the source-specific information following downstream processing. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 15/650832 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6876 (20130101) C12Q 2531/113 (20130101) C12Q 2537/143 (20130101) C12Q 2563/149 (20130101) C12Q 2565/519 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466119 | Campbell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NextInput, Inc. (San Jose, California) |
| ASSIGNEE(S) | NEXTINPUT, INC. (Mountain View, California) |
| INVENTOR(S) | Ian Campbell (San Jose, California); Ryan Diestelhorst (San Jose, California); Dan Benjamin (San Jose, California); Steven S. Nasiri (Los Altos Hills, California) |
| ABSTRACT | An example MEMS force sensor is described herein. The MEMS force sensor can include a cap for receiving an applied force and a sensor bonded to the cap. A trench and a cavity can be formed in the sensor. The trench can be formed along at least a portion of a peripheral edge of the sensor. The cavity can define an outer wall and a flexible sensing element, and the outer wall can be arranged between the trench and the cavity. The cavity can be sealed between the cap and the sensor. The sensor can also include a sensor element formed on the flexible sensing element. The sensor element can change an electrical characteristic in response to deflection of the flexible sensing element. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/178976 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/18 (20130101) Original (OR) Class G01L 1/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466416 | Magnusson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Robert Magnusson (Arlington, Texas); Mehrdad Shokooh-Saremi (Mashhad, Iran) |
| ABSTRACT | Multilevel leaky-mode optical elements, including reflectors, polarizers, and beamsplitters. Some of the elements have a plurality of spatially modulated periodic layers coupled to a substrate. For infrared applications, the optical elements may have a bandwidth larger than 600 nanometers. |
| FILED | Monday, October 16, 2017 |
| APPL NO | 15/785116 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/203 (20130101) G02B 5/285 (20130101) G02B 5/288 (20130101) G02B 5/0833 (20130101) G02B 5/1823 (20130101) G02B 5/3041 (20130101) G02B 6/14 (20130101) G02B 6/124 (20130101) G02B 6/126 (20130101) Original (OR) Class G02B 2006/12038 (20130101) G02B 2006/12061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466461 | Lukes |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Agile Focus Designs, LLC (Bozeman, Montana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sarah Lukes (Bozeman, Montana) |
| ABSTRACT | A dynamic focus and zoom system for use with wide-field, confocal and multiphoton microscopes having first, second and third MEMS mirrors situated within a housing. First and second fixed lenses form an optical relay. A prism/mirror is situated proximate to a first portal in the housing and is aligned linearly with the optical relay and a first MEMS mirror. The second MEMS mirror is proximate to and at a ninety-degree angle relative to the first MEMS mirror, which is at a forty-five-degree angle to the second fixed lens. The second MEMS mirror, third fixed lens and third MEMS mirror are aligned linearly, with the third fixed lens situated between the second and third MEMS mirrors. The third MEMS mirror is proximate to a second portal in the housing. The third MEMS mirror is situated adjacent to the prism/mirror. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/258455 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 15/14 (20130101) G02B 21/006 (20130101) G02B 21/025 (20130101) Original (OR) Class G02B 21/241 (20130101) G02B 26/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10467400 | Shyu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Chi-Ren Shyu (Columbia, Missouri); Hongfei Cao (Lake Forest, California); Matthew Klaric (Burke, Virginia); Jeffrey Uhlmann (Holts Summit, Missouri) |
| ABSTRACT | Method, system and media for authenticating a subject as a user. Embodiments generate visual stories specific to the user and for which the subject must select the corresponding images from among a plurality of decoy images. Gaze tracking can be used to determine which images the user has selected without allowing an observer to learn which images have been selected. Images for the visual story can be retrieved from the user's social networking profile, and corresponding text storied generated to indicate which images should be selected. Multiple security levels are possible by varying the number of story images and decoy images. |
| FILED | Friday, October 16, 2015 |
| APPL NO | 15/517343 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/36 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/72 (20130101) G06K 9/00604 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468548 | Sachet et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Edward Sachet (Raleigh, North Carolina); Jon-Paul Maria (Raleigh, North Carolina) |
| ABSTRACT | A detector that includes an all-oxide, Schottky-type heterojunction. The “metal” side of the heterojunction is formed, for example, from a dysprosium (“Dy”) doped cadmium oxide (“CdO”) (i.e., CdO:Dy). The semiconductor side of the heterojunction is formed, for example, from cadmium magnesium oxide (“CdMgO”). On the metal side of the junction, “hot” electrons are created through the excitation of surface plasmon polaritons by infrared radiation. The hot electrons are able to cross the Schottky-type barrier of the heterojunction into the conduction band of the semiconductor where they can be detected. The working wavelength of infrared radiation that is being detected can be adjusted or tuned by modifying the Dy content of Dy-doped CdO. The height of the Schottky-type barrier can also be adjusted by modifying the composition of CdMgO, which allows for the optimization of the Schottky-type barrier height for a given working wavelength. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/142494 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/108 (20130101) H01L 31/109 (20130101) Original (OR) Class H01L 31/0336 (20130101) H01L 31/02363 (20130101) H01L 31/02963 (20130101) H01L 31/02966 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10469320 | Dwaraki et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Deutsche Telekom AG (Bonn, Germany); University of Massachusetts (Boston, Massachusetts); Infinera Corporation (Sunnyvale, California) |
| ASSIGNEE(S) | DEUTSCHE TELEKOM AG (Bonn, Germany); UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); INFINERA CORPORATION (Sunnyvale, California) |
| INVENTOR(S) | Abhishek Dwaraki (Amherst, Massachusetts); Sriram Natarajan (San Jose, California); Tilman Wolf (Amherst, Massachusetts); Srini Seetharaman (Sunnyvale, California) |
| ABSTRACT | A versioning system for network state of a network includes: a server, configured to execute a versioning controller, the versioning controller being configured to communicate with a plurality of data plane devices of the network and store a plurality of network states in a local non-transitory memory corresponding to the server, wherein the plurality of network states stored in the local non-transitory memory include a current authoritative network state and a plurality of previous network states each corresponding to a modification of a flow within the network; and the plurality of data plane devices, configured to notify the server of flow modifications made by respective data plane devices and to receive the current authoritative network state from the server. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/141834 |
| ART UNIT | 2458 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/12 (20130101) H04L 41/046 (20130101) H04L 41/0859 (20130101) H04L 41/0873 (20130101) Original (OR) Class H04L 41/0893 (20130101) H04L 45/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10469763 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Xinyu Zhang (Madison, Wisconsin); Chi Zhang (Madison, Wisconsin); Shilin Zhu (Madison, Wisconsin) |
| ABSTRACT | A visual privacy system unilaterally blocks rolling shutter cameras by providing a periodically interrupted ambient light source imposing bright and dark bands on the image yet at a frequency imperceptible to human observers in the environment. Communication of the modulation pattern to authorized cameras allows unaffected imaging in these regions by authorized individuals. The system also contemplates operation in a barcoding mode with a light modulation providing embedded barcodes that can be extracted from images taken in the region to indicate that the images were improperly acquired and to block the images in certain applications. |
| FILED | Wednesday, June 07, 2017 |
| APPL NO | 15/616386 |
| ART UNIT | 2696 — Selective Visual Display Systems |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/2256 (20130101) H04N 5/2351 (20130101) H04N 5/2353 (20130101) H04N 5/2354 (20130101) Original (OR) Class H04N 5/23203 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 37/0227 (20130101) H05B 37/0272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10469833 | Hua et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Hong Hua (Tucson, Arizona); Bahram Javidi (Storrs, Connecticut) |
| ABSTRACT | A wearable 3D augmented reality display and method, which may include 3D integral imaging optics. |
| FILED | Thursday, March 05, 2015 |
| APPL NO | 15/122497 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 17/086 (20130101) G02B 27/0172 (20130101) G02B 2027/0127 (20130101) G02B 2027/0129 (20130101) G02B 2027/0134 (20130101) G02B 2027/0185 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00671 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Pictorial Communication, e.g Television H04N 13/31 (20180501) Original (OR) Class H04N 13/204 (20180501) H04N 13/344 (20180501) H04N 2213/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10464015 | Worsley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Marcus Worsley (Hayward, California); Patrick Campbell (Oakland, California); Sangil Kim (Pleasanton, California); Matthew Merrill (Dublin, California) |
| ABSTRACT | In one embodiment, a separation membrane includes: a porous support structure; and at least one alkali metal hydroxide disposed within pores of the porous support structure. In another embodiment, a method for separating acidic gases from a gas mixture includes exposing the gas mixture to a separation membrane at an elevated temperature, where the separation membrane includes a porous support and at least one molten alkali metal hydroxide disposed within pores of the porous support. |
| FILED | Thursday, May 19, 2016 |
| APPL NO | 15/159681 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/40 (20130101) B01D 53/62 (20130101) B01D 53/82 (20130101) B01D 53/228 (20130101) Original (OR) Class B01D 53/508 (20130101) B01D 53/565 (20130101) B01D 61/38 (20130101) B01D 69/02 (20130101) B01D 69/10 (20130101) B01D 69/12 (20130101) B01D 71/02 (20130101) B01D 71/022 (20130101) B01D 71/024 (20130101) B01D 2053/221 (20130101) B01D 2251/306 (20130101) B01D 2251/604 (20130101) B01D 2257/50 (20130101) B01D 2257/302 (20130101) B01D 2257/404 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) B01D 2311/13 (20130101) B01D 2325/02 (20130101) B01D 2325/04 (20130101) B01D 2325/26 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464018 | Voskian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Sahag Voskian (Cambridge, Massachusetts); Trevor Alan Hatton (Sudbury, Massachusetts) |
| ABSTRACT | The present disclosure generally relates to apparatuses, systems, and methods for separating a target species (e.g., CO2) from a gas mixture (e.g., gas stream) via an electrochemical process. |
| FILED | Wednesday, October 26, 2016 |
| APPL NO | 15/335258 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 53/326 (20130101) Original (OR) Class B01D 2257/504 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464031 | Lewis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jennifer A. Lewis (Cambridge, Massachusetts); Thomas J. Ober (Cambridge, Massachusetts) |
| ABSTRACT | A microfluidic printing nozzle for 3D printing may include a mixing chamber, a first inlet for connecting with a first ink source, the first inlet located at a first end of the mixing chamber, and a second inlet for connecting with a second ink source, the second inlet located at the first end of the mixing chamber. An outlet may be located at a second end of the mixing chamber, and a generally cylindrical impeller may be rotatably disposed in the mixing chamber between the first end and the second end. The cylindrical impeller may include an outer surface, and the outer surface of the impeller includes a groove, a protrusion, or both, to facilitate mixing of fluidic inks flowing from the first end to the second end of the mixing chamber. |
| FILED | Monday, September 10, 2018 |
| APPL NO | 16/126723 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0861 (20130101) B01F 3/0865 (20130101) B01F 3/1221 (20130101) B01F 7/06 (20130101) B01F 7/248 (20130101) B01F 13/0059 (20130101) B01F 13/0064 (20130101) B01F 15/00253 (20130101) B01F 15/00389 (20130101) Original (OR) Class Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/30 (20130101) Preparing Clay; Producing Mixtures Containing Clay or Cementitious Material, e.g Plaster B28C 5/026 (20130101) B28C 5/1292 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/209 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/175 (20130101) B41J 2/211 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464815 | Melsert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southern Research Institute (Birmingham, Alabama) |
| ASSIGNEE(S) | Southern Research Institute (Birmingham, Alabama) |
| INVENTOR(S) | Ryan Melsert (Reno, Nevada); Santosh Kumar Gangwal (Cary, North Carolina); Tim A. Hansen (Raleigh, North Carolina) |
| ABSTRACT | A thermochemical energy storage system and method of storing thermal energy are disclosed. The energy storing system described herein comprises a reactor comprising a CO2 sorbent comprising i) CaO and mayenite or ii) Li4SiO4, or a combination thereof, and b) a CO2 source, wherein the CO2 source is in fluid communication with the reactor to allow flow of CO2 between the CO2 source and the reactor. Further, methods are disclosed for storing thermal energy through a wide temperature range. |
| FILED | Wednesday, June 15, 2016 |
| APPL NO | 15/183101 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/10 (20130101) B01J 20/041 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/50 (20170801) Original (OR) Class C01B 32/60 (20170801) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/08 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/13 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464960 | Job et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Saudi Aramco Technologies Company (Dhahran, Saudi Arabia) |
| ASSIGNEE(S) | Saudi Aramco Technologies Company (Dhahran, Saudi Arabia) |
| INVENTOR(S) | Gabriel E. Job (Ithaca, New York); Jay J. Farmer (Ithaca, New York); Anna E. Cherian (Ithaca, New York) |
| ABSTRACT | The present invention describes metal salen complexes having dianionic counterions. Such complexes can be readily precipitated and provide an economical method for the purification and isolation of the complexes, and are useful to prepare novel polymer compositions. |
| FILED | Thursday, July 28, 2016 |
| APPL NO | 15/222502 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 11/005 (20130101) C07F 15/065 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 64/34 (20130101) C08G 64/0208 (20130101) C08G 65/266 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465181 | Froehlich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LALLEMAND HUNGARY LIQUIDITY MANAGEMENT LLC (Budapest, Hungary) |
| ASSIGNEE(S) | Lallemand Hungary Liquidity Management LLC (Budapest, Hungary) |
| INVENTOR(S) | Allan Froehlich (Hartland, Vermont); Brooks Henningsen (Lebanon, New Hampshire); Sean Covalla (Thetford Center, Vermont); Rintze M. Zelle (Lebanon, New Hampshire) |
| ABSTRACT | There is provided an engineered host cells comprising (a) one or more mutations in one or more endogenous genes encoding a protein associated with iron metabolism; and (b) at least one gene encoding a polypeptide having xylose isomerase activity, and methods of their use thereof. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/884449 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/395 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/92 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) Enzymes C12Y 503/01005 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465213 | Liao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cargill, Incorporated (Wayzata, Minnesota) |
| ASSIGNEE(S) | CARGILL, INCORPORATED (Wayzata, Minnesota) |
| INVENTOR(S) | Hans Liao (Superior, Colorado); Eileen Spindler (Lafayette, Colorado); Joseph R. Warner (San Clemente, California); Michael Louie (Broomfield, Colorado); Wendy Ribble (Arvada, Colorado); Brittany Prather (Boulder, Colorado); Ron Evans (Boulder, Colorado); Tanya E. W. Lipscomb (Boulder, Colorado); Michael D. Lynch (Westminster, Colorado) |
| ABSTRACT | This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a fatty acid or fatty acid derived product, wherein the modified microorganism produces fatty acyl-CoA intermediates via a malonyl-CoA dependent but malonyl-ACP independent mechanism. |
| FILED | Tuesday, March 29, 2016 |
| APPL NO | 15/083924 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/1029 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) C12P 7/40 (20130101) C12P 7/6409 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/19 (20130101) Enzymes C12Y 101/01157 (20130101) C12Y 103/01009 (20130101) C12Y 203/01194 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465305 | Jahnke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
| ASSIGNEE(S) | FUELCELL ENERGY, INC. (Danbury, Connecticut) |
| INVENTOR(S) | Fred C. Jahnke (Rye, New York); Matthew Lambrech (Sherman, Connecticut) |
| ABSTRACT | A system for producing at least one of hydrogen or carbon monoxide includes at least one fuel cell, including an anode and a cathode separated by an electrolyte matrix. The at least one fuel cell further includes a power supply for applying a reverse voltage to the at least one fuel cell to operate the fuel cell in reverse as an electrolyzer. The anode is configured to receive a partially-reformed fuel and output a gas comprising hydrogen. The cathode is configured to output a gas comprising carbon dioxide and oxygen. The system further includes at least one oxidizer configured to receive the carbon dioxide and oxygen from the cathode and fuel from a fuel supply, the at least one oxidizer configured to output a partially-oxidized fuel comprising carbon monoxide, carbon dioxide, and hydrogen. |
| FILED | Tuesday, May 15, 2018 |
| APPL NO | 15/980356 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 15/08 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/12 (20130101) H01M 8/14 (20130101) H01M 8/0618 (20130101) H01M 8/04007 (20130101) H01M 2008/147 (20130101) H01M 2300/0051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465565 | Spiry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Irina Pavlovna Spiry (Glenville, New York); Albert Santo Stella (Voorheesville, New York); John Brian McDermott (Rexford, New York); Stephen Sanborn (Copake, New York) |
| ABSTRACT | A CO2 energy storage system includes a storage tank that stores a CO2 slurry, including dry ice and liquid CO2, at CO2 triple point temperature and pressure conditions. The storage system also includes a first pump coupled in flow communication with the storage tank. The first pump is configured to receive the CO2 slurry from the storage tank and to increase a pressure of the CO2 slurry to a pressure above the CO2 triple point pressure. The energy storage system further includes a contactor coupled in flow communication with the first pump. The contactor is configured to receive the high pressure CO2 slurry from the pump and to receive a first flow of gaseous CO2 at a pressure above the CO2 triple point pressure. The gaseous CO2 is contacted and then condensed by the melting dry ice in the slurry to generate liquid CO2. |
| FILED | Friday, December 02, 2016 |
| APPL NO | 15/367959 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 7/16 (20130101) F01K 13/006 (20130101) F01K 25/103 (20130101) Original (OR) Class Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 5/00 (20130101) F17C 7/00 (20130101) F17C 7/02 (20130101) F17C 7/04 (20130101) F17C 2201/054 (20130101) F17C 2221/013 (20130101) F17C 2223/033 (20130101) F17C 2223/043 (20130101) F17C 2223/046 (20130101) F17C 2223/0184 (20130101) F17C 2223/0192 (20130101) F17C 2225/033 (20130101) F17C 2225/035 (20130101) F17C 2225/046 (20130101) F17C 2225/0123 (20130101) F17C 2225/0184 (20130101) F17C 2227/039 (20130101) F17C 2227/0128 (20130101) F17C 2227/0135 (20130101) F17C 2227/0306 (20130101) F17C 2227/0309 (20130101) F17C 2227/0327 (20130101) F17C 2227/0339 (20130101) F17C 2227/0393 (20130101) F17C 2265/022 (20130101) F17C 2270/0581 (20130101) Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 1/0027 (20130101) F25J 1/0095 (20130101) F25J 1/0201 (20130101) F25J 5/007 (20130101) F25J 2205/02 (20130101) F25J 2205/20 (20130101) F25J 2205/90 (20130101) F25J 2235/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465984 | Baxter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Larry Baxter (Orem, Utah); Andrew Baxter (Spanish Fork, Utah); Eric Mansfield (Spanish Fork, Utah); Aaron Sayre (Spanish Fork, Utah); Kyler Stitt (Lindon, Utah); Christopher Hoeger (Provo, Utah); Stephanie Burt (Provo, Utah); David Frankman (Provo, Utah) |
| ASSIGNEE(S) | Hall Labs LLC (Provo, Utah) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); Andrew Baxter (Spanish Fork, Utah); Eric Mansfield (Spanish Fork, Utah); Aaron Sayre (Spanish Fork, Utah); Kyler Stitt (Lindon, Utah); Christopher Hoeger (Provo, Utah); Stephanie Burt (Provo, Utah); David Frankman (Provo, Utah) |
| ABSTRACT | Condensable vapors such as carbon dioxide are separated from light gases in a process stream. The systems and methods employ a circulating fluidized particle bed cooled by an out-bed heat exchanger to desublimate the solid form of condensable vapors from the process stream. Gas and solids may be sorted in a separator, and the solids may then be subcooled in a heat exchanger. The condensable vapors may be condensed on the bed particles or in the heat exchanger while the light gases from the process stream, which are not condensed, form a separated light-gas stream. |
| FILED | Monday, January 23, 2017 |
| APPL NO | 15/412484 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 53/002 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 3/067 (20130101) Original (OR) Class F25J 2205/10 (20130101) F25J 2205/20 (20130101) F25J 2205/30 (20130101) F25J 2270/04 (20130101) F25J 2270/90 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466183 | Seetho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Isaac Seetho (Hayward, California); Maurice B. Aufderheide (Livermore, California); Stephen G. Azevedo (Livermore, California); William D. Brown (Antioch, California); Kyle Champley (Walnut Creek, California); Daniel Schneberk (Ripon, California); G. Patrick Roberson (Livermore, California); Jeffrey S. Kallman (Pleasanton, California); Harry E. Martz, Jr. (Livermore, California); Jerel A. Smith (Boulder Creek, California) |
| ABSTRACT | A system for characterizing the material of an object scanned via a dual-energy computed tomography scanner is provided. The system generates photoelectric and Compton sinograms based on a photoelectric-Compton decomposition of low-energy and high-energy sinograms generated from the scan and based on a scanner spectral response model. The system generates a Compton volume with Compton attenuation coefficients from the Compton sinogram and a photoelectric volume with photoelectric attenuation coefficients from the photoelectric sinogram. The system generates an estimated effective atomic number for a voxel and an estimated electron density for the voxel from the Compton attenuation coefficient and photoelectric coefficient for the voxel and scanner-specific parameters. The system then characterizes the material within the voxel based on the estimated effective atomic number and estimated electron density for the voxel. This information can be used to provide a mapping of known effective atomic numbers and known electron densities to known materials. |
| FILED | Monday, October 31, 2016 |
| APPL NO | 15/339821 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/046 (20130101) Original (OR) Class G01N 23/083 (20130101) G01N 2223/063 (20130101) G01N 2223/423 (20130101) Image Data Processing or Generation, in General G06T 11/005 (20130101) G06T 2207/10081 (20130101) G06T 2211/408 (20130101) G06T 2211/416 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466202 | Ibrahim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Yehia M. Ibrahim (Richland, Washington); Sandilya Garimella (Richland, Washington); Richard D. Smith (Richland, Washington) |
| ABSTRACT | Methods and apparatuses for ion peak compression and increasing resolution of ions are disclosed. Packets of ions are introduced into a device. A first electric field is applied for dispersing the ion packets temporally or spatially according to their mobilities. A second intermittent traveling wave is applied for regrouping or merging the dispersed ion packets into a lesser number of trapping regions with narrower peaks. The ions packets are compressed into the narrower peak regions by varying a duty cycle of the intermittent traveling wave. |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/027092 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466207 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Xingwei Wang (Shrewsbury, Massachusetts); Nan Wu (Sunderland, Massachusetts) |
| ABSTRACT | In an embodiment, a sensor comprises a waveguide comprising a photoacoustic generation element disposed on the waveguide, the photoacoustic generation element comprising a photoabsorptive material; and a sensing element comprising an optical acoustic wave detector. In another embodiment, a sensing system comprises the sensor and a laser. In yet another embodiment, a method of sensing comprises providing the sensing system; heating the photoabsorptive material with a laser to generate an acoustic signal; sensing an intensity of laser light reflected by the optical acoustic wave detector to detect the acoustic signal; and determining a time of flight of the acoustic signal between the generation and the detection to determine a change in a parameter change in a medium between the photoabsorptive material and the optical acoustic wave detector. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/569112 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/22 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/34 (20130101) G01N 29/2418 (20130101) G01N 29/2462 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10467159 | Beard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARM LTD (Cambridge, United Kingdom) |
| ASSIGNEE(S) | Arm Limited (Cambridge, United Kingdom) |
| INVENTOR(S) | Jonathan Curtis Beard (Austin, Texas); Roxana Rusitoru (Cambridge, United Kingdom); Curtis Glenn Dunham (Austin, Texas) |
| ABSTRACT | A memory node controller for a node of a data processing network, the network including at least one computing device and at least one data resource, each data resource addressed by a physical address. The node is configured to couple the at least one computing device with the at least one data resource. Elements of the data processing network are addressed via a system address space. The memory node controller includes a first interface to the at least one data resource, a second interface to the at least one computing device, and a system to physical address translator cache configured to translate a system address in the system address space to a physical address in the physical address space of the at least one data resource. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 15/650008 |
| ART UNIT | 2135 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0824 (20130101) G06F 12/0826 (20130101) G06F 12/1036 (20130101) G06F 12/1072 (20130101) G06F 12/1081 (20130101) G06F 13/1663 (20130101) G06F 13/1694 (20130101) Original (OR) Class G06F 2212/651 (20130101) G06F 2212/657 (20130101) G06F 2212/2542 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 49/35 (20130101) H04L 49/252 (20130101) H04L 49/505 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10467474 | Malinas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, Minnesota) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Rebecca Malinas (Northville, Michigan); Tu-Thach Quach (Albuquerque, Minnesota); Mark W. Koch (Albuquerque, Minnesota) |
| ABSTRACT | The various technologies presented herein relate to detecting one or more vehicle tracks in radar imagery. A CCD image can be generated from a first SAR image and a second SAR image captured for a common scene, wherein the second SAR image may include a vehicle track that is not present in the first SAR image. A Radon transform (RT) process can be applied to each pixel in the CCD image, and further, a radial derivative (RDRT) can be determined for each pixel from RT values derived for each pixel. Each pixel can be labelled as being related to a track, or not, based upon a unary cost obtained from the RDRT value of that pixel, combined with a probability of the pixel label based upon labels applied to neighboring pixels. A labelled representation of the CCD image can be generated based upon the determination of “track” or “not track”. |
| FILED | Monday, July 11, 2016 |
| APPL NO | 15/207290 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/904 (20190501) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/623 (20130101) G06K 9/00651 (20130101) Original (OR) Class G06K 9/4642 (20130101) G06K 9/6232 (20130101) G06K 2009/4666 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468144 | Mirsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NuScale Power, LLC (Corvallis, Oregon) |
| ASSIGNEE(S) | NUSCALE POWER, LLC (Portland, Oregon) |
| INVENTOR(S) | Stephen M. Mirsky (Corvallis, Oregon); Jose N. Reyes, Jr. (Corvallis, Oregon) |
| ABSTRACT | A system for storing nuclear fuel assemblies includes a plurality of cells housed within a support structure. A first cell may house a first fuel assembly and a second cell may house a second fuel assembly. A plurality of compartments separate the plurality of cells and provide passageways for coolant entering a bottom end of the support structure to remove heat from the nuclear fuel assemblies. A first perforation transfers coolant between the first cell and one or more of the compartments, and a second perforation transfers coolant between the second cell and the one or more compartments. At least a portion of the coolant entering the bottom end of the support structure is transferred between the plurality of cells and the plurality of compartments. Two or more fuel storage racks may be stacked together in alternating fuel patterns to facilitate cooling the fuel assemblies with liquid or air. |
| FILED | Thursday, August 06, 2015 |
| APPL NO | 14/820389 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 15/18 (20130101) G21C 19/07 (20130101) Original (OR) Class G21C 19/08 (20130101) G21C 19/40 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 7/015 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468151 | Alam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Muhammad Ashraful Alam (West Lafayette, Indiana); Ruiyi Chen (Hangzhou, China PRC); Suprem R. Das (West Lafayette, Indiana); David B. Janes (West Lafayette, Indiana); Changwook Jeong (West Lafayette, Indiana); Mark Lundstrom (Lafayette, Indiana) |
| ABSTRACT | Hybrid transparent conducting materials are disclosed with combine a polycrystalline film and conductive nanostructures, in which the polycrystalline film is “percolation doped” with the conductive nanostructures. The polycrystalline film preferably is a single atomic layer thickness of polycrystalline graphene, and conductive nanostructures preferably are silver nanowires. |
| FILED | Monday, October 24, 2016 |
| APPL NO | 15/332938 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/13439 (20130101) G02F 2202/36 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) Original (OR) Class H01B 1/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/413 (20130101) H01L 29/1606 (20130101) H01L 31/028 (20130101) H01L 31/1864 (20130101) H01L 31/1884 (20130101) H01L 31/022466 (20130101) H01L 31/022491 (20130101) H01L 51/442 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/547 (20130101) Y02E 10/549 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2438 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468241 | Scime et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | West Virginia University (Morgantown, West Virginia) |
| ASSIGNEE(S) | West Virginia University (Morgantown, West Virginia) |
| INVENTOR(S) | Earl Scime (Morgantown, West Virginia); Amy M. Keesee (Bridgeport, West Virginia); Matthew Phillip Dugas (North Oaks, Minnesota); Steven Brian Ellison (Woodbury, Minnesota); Joseph Christopher David Tersteeg (Columbia Heights, Minnesota); Drew B. Elliott (Morgantown, West Virginia) |
| ABSTRACT | Disclosed are various examples related to ion or particle spectrometry utilizing a monolithic collimator and energy analyzer. In one example, a particle selection device includes a single substrate including a curved channel energy analyzer section and a straight channel collimator section, wherein particles pass through the collimator section and enter the energy analyzer section of the substrate. The channel outlets in the collimator section are aligned with the channel inlets of the energy analyzer section. Electric and/or magnetic fields can be applied across the channels of the energy analyzer for ion or particle discrimination. A particle detector at the outlet of the energy analyzer section can provide indications of detected ions and/or particles. |
| FILED | Tuesday, April 04, 2017 |
| APPL NO | 15/479231 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/06 (20130101) H01J 49/48 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468684 | Teng |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of New Hampshire (Durham, New Hampshire) |
| ASSIGNEE(S) | The University of New Hampshire (Durham, New Hampshire) |
| INVENTOR(S) | Xiaowei Teng (Durham, New Hampshire) |
| ABSTRACT | A composition and method of preparation of mixed valence manganese oxide, nickel-doped mixed valence manganese oxide and cobalt-doped mixed valence manganese oxide nanoparticles as well as tri-manganese tetroxide, nickel-doped tri-manganese tetroxide and cobalt-doped tri-manganese tetroxide nanoparticles for use as electrodes for aqueous energy storage devices. |
| FILED | Friday, June 12, 2015 |
| APPL NO | 14/737823 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 45/02 (20130101) C01G 51/00 (20130101) C01G 53/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/50 (20130101) C01P 2002/54 (20130101) C01P 2002/72 (20130101) C01P 2002/80 (20130101) C01P 2004/04 (20130101) C01P 2004/64 (20130101) C01P 2006/40 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/46 (20130101) H01G 11/68 (20130101) H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/50 (20130101) H01M 4/625 (20130101) Original (OR) Class H01M 10/36 (20130101) H01M 2300/0002 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468788 | Shapnek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Daniel M. C. Odell (Aiken, South Carolina); Kevin Thomas (Las Vegas, Nevada) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Daniel M. C. Odell (Aiken, South Carolina); Kevin Thomas (Las Vegas, Nevada) |
| INVENTOR(S) | Lawrence R. Shapnek (Cedar Crest, New Mexico); Charles S. Field, III (Shuqualak, Mississippi); WVenner Saul (Los Lunas, New Mexico); Nathan A. Davey (Sandia Park, New Mexico); Andrew Lee McCourt (Belen, New Mexico); Dennis J. De Smet (Bosque Farms, New Mexico); Charles A. Walker (Albuquerque, New Mexico); Daniel M. C. Odell (Aiken, South Carolina); Kevin Thomas (Las Vegas, Nevada) |
| ABSTRACT | A device for rendering safe a detonator firing circuit by short circuiting multiple conductors in the circuit includes a base portion and cable piercing members. The base portion has a cylindrical block and apertures for retentively receiving the cable piercing members. The cable piercing member has a first end to impinge on and penetrate a cable insulation when forcibly attached to an external surface of the cable. The cable piercing member has a low electrical resistance and impedance to generate a short circuit between conductors of the cable. Also, a method for rendering safe a detonator firing circuit of by short circuiting multiple conductor cables or a pigtail connector of a detonator system. |
| FILED | Wednesday, August 16, 2017 |
| APPL NO | 15/678638 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/18 (20130101) Blasting F42D 1/05 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/2404 (20130101) Original (OR) Class H01R 24/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10470287 | Kobernik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PHOENIX LLC (Monona, Wisconsin) |
| ASSIGNEE(S) | PHOENIX LLC (Monona, Wisconsin) |
| INVENTOR(S) | Arne Kobernik (Monona, Wisconsin); Carl Sherven (Monona, Wisconsin); Casey Lamers (Monona, Wisconsin); Chris Seyfert (Monona, Wisconsin); Evan Sengbusch (Monona, Wisconsin); Gabriel Becerra (Monona, Wisconsin); Jin Lee (Monona, Wisconsin); Logan Campbell (Monona, Wisconsin); Mark Thomas (Monona, Wisconsin); Michael Taylor (Monona, Wisconsin); Preston Barrows (Monona, Wisconsin); Ross Radel (Monona, Wisconsin); Tye Gribb (Monona, Wisconsin) |
| ABSTRACT | Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196720 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10470288 | Kobernik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PHOENIX LLC (Monona, Wisconsin) |
| ASSIGNEE(S) | PHOENIX LLC (Monona, Wisconsin) |
| INVENTOR(S) | Arne Kobernik (Monona, Wisconsin); Carl Sherven (Monona, Wisconsin); Casey Lamers (Monona, Wisconsin); Chris Seyfert (Monona, Wisconsin); Evan Sengbusch (Monona, Wisconsin); Gabriel Becerra (Monona, Wisconsin); Jin Lee (Monona, Wisconsin); Logan Campbell (Monona, Wisconsin); Mark Thomas (Monona, Wisconsin); Michael Taylor (Monona, Wisconsin); Preston Barrows (Monona, Wisconsin); Ross Radel (Monona, Wisconsin); Tye Gribb (Monona, Wisconsin) |
| ABSTRACT | Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196556 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/08 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/54 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10463249 | Stone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Leland Stone (San Francisco, California); Dorion Liston (Boulder Creek, California) |
| ABSTRACT | An eye movement-based methodology and assessment tool may be used to quantify many aspects of human dynamic visual processing using a relatively simple and short oculomotor task, noninvasive video-based eye tracking, and validated oculometric analysis techniques. By examining the eye movement responses to a task including a radially-organized appropriately randomized sequence of Rashbass-like step-ramp pursuit-tracking trials, distinct performance measurements may be generated that may be associated with, for example, pursuit initiation (e.g., latency and open-loop pursuit acceleration), steady-state tracking (e.g., gain, catch-up saccade amplitude, and the proportion of the steady-state response consisting of smooth movement), direction tuning (e.g., oblique effect amplitude, horizontal-vertical asymmetry, and direction noise), and speed tuning (e.g., speed responsiveness and noise). This quantitative approach may provide fast and results (e.g., a multi-dimensional set of oculometrics and a single scalar impairment index) that can be interpreted by one without a high degree of scientific sophistication or extensive training. |
| FILED | Monday, August 14, 2017 |
| APPL NO | 15/676875 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/032 (20130101) A61B 3/0041 (20130101) A61B 3/0091 (20130101) A61B 3/113 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464271 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Institute of Aerospace Associates (Hampton, Virginia); U.S.A., as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Jae-Woo Kim (Newport News, Virginia); Emilie J. Siochi (Newport News, Virginia); Kristopher E. Wise (Poquoson, Virginia); John W. Connell (Yorktown, Virginia); Yi Lin (Yorktown, Virginia); Russell A. Wincheski (Williamsburg, Virginia); Dennis C. Working (Norfolk, Virginia) |
| ABSTRACT | A method allows for preparation of CNT nanocomposites having improved mechanical, electrical and thermal properties. Structured carbon nanotube forms such as sheet, yarn, and tape are modified with π-conjugated conductive polymers, including polyaniline (PANI), fabricated by in-situ polymerization. The PANI modified CNT nanocomposites are subsequently post-processed to improve mechanical properties by hot press and carbonization. |
| FILED | Saturday, August 24, 2013 |
| APPL NO | 13/987706 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/12 (20130101) B29C 70/40 (20130101) B29C 70/42 (20130101) B29C 70/543 (20130101) Original (OR) Class B29C 70/682 (20130101) B29C 70/887 (20130101) B29C 71/02 (20130101) B29C 2071/022 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465281 | Bly |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Vincent T. Bly (Springfield, Virginia) |
| ABSTRACT | The present invention relates to a high resolution additive manufacturing method, including: creating a rigid shell of a stable material on all surfaces except for a sprue of a three dimensional (3D) polymer part using a chemical vapor deposition (CVD) process which includes: depositing the stable material at a process temperature of 100° C. or less, and operating at, or near, atmospheric pressure; and removing the 3D polymer part by accessing the inside of the rigid shell through the sprue to allow dissolution of the 3D polymer part, thereby leaving a replicated rigid shell of the stable material. |
| FILED | Monday, August 15, 2016 |
| APPL NO | 15/236551 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/135 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/01 (20130101) Original (OR) Class C23C 16/16 (20130101) C23C 16/452 (20130101) C23C 16/4412 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466030 | Gurley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AUBURN UNIVERSITY (Auburn, Alabama) |
| ASSIGNEE(S) | Auburn University (Auburn, Alabama) |
| INVENTOR(S) | Austin R. Gurley (Leeds, Alabama); David G. Beale (Auburn, Alabama); Royall M. Broughton (Auburn, Alabama) |
| ABSTRACT | A method for determining a length of a span of electrically conductive material, comprising a first voltage measurement across the entire span, and a second voltage measurement across a constant-length segment of the span. The dual measurements allow the calculation of the span length in a manner that is robust to many disturbances including ambient temperature, material temperature, and material stress and fatigue. |
| FILED | Friday, May 12, 2017 |
| APPL NO | 15/593885 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/02 (20130101) G01B 7/14 (20130101) Original (OR) Class G01B 11/0608 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/12 (20130101) G01D 5/16 (20130101) G01D 5/266 (20130101) G01D 5/347 (20130101) G01D 5/35383 (20130101) Coding; Decoding; Code Conversion in General H03M 1/282 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466108 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ari D. Brown (Ellicott City, Maryland); Kevin H. Miller (Washington, District of Columbia); Edward J. Wollack (Clarksville, Maryland) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Ari D. Brown (Ellicott City, Maryland); Kevin H. Miller (Washington, District of Columbia); Edward J. Wollack (Clarksville, Maryland) |
| ABSTRACT | The present invention relates to an electrically thin molybdenum thin film absorber coating for a detector, that is capable of absorbing a fraction of incident electromagnetic radiation over a 1-15 THz spectral range. |
| FILED | Thursday, August 24, 2017 |
| APPL NO | 15/685307 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/20 (20130101) G01J 5/024 (20130101) Original (OR) Class G01J 5/046 (20130101) G01J 5/0853 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3581 (20130101) G01N 22/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14669 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468722 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Simon C. Jones (Whittier, California); Victoria K. Davis (Santa Clarita, California); Christopher M. Bates (Monrovia, California); Nebojsa Momcilovic (Vienna, Virginia); Brett M. Savoie (Pasadena, California); Michael A. Webb (Pasadena, California); Thomas F. Miller, III (South Pasadena, California); Robert H. Grubbs (South Pasadena, California); Jennifer M. Murphy (Los Angeles, California) |
| ABSTRACT | Processes and reaction mixtures including non-aqueous solvent mixtures are presented. Non-aqueous solvent mixtures including fluoride salt and non-aqueous solvent combinations are provided that possess high fluoride ion concentrations useful for a range of applications, including organic synthesis. Further non-aqueous solvent mixtures are provided including a salt possessing a non-fluoride anion and a non-aqueous solvent that, when contacted with aqueous fluoride-containing reagents, extract fluoride ions to form non-aqueous fluoride-ion solutions possessing high fluoride-ion concentrations. The salts include an organic cation that does not possess a carbon in the β-position or does not possess a carbon in the β-position having a bound hydrogen. This salt structure facilitates its ability to be made anhydrous without decomposition. Example anhydrous fluoride salts include (2,2-dimethylpropyl)trimethylammonium fluoride and bis(2,2-dimethylpropyl)dimethylammonium fluoride. The combination of these fluoride salts with at least one fluorine-containing non-aqueous solvent (e.g., bis(2,2,2-trifluoroethyl)ether; (BTFE)) promotes solubility of the salt within the non-aqueous solvents. |
| FILED | Thursday, August 04, 2016 |
| APPL NO | 15/229026 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 209/68 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0568 (20130101) Original (OR) Class H01M 10/0569 (20130101) H01M 2300/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468955 | Ricci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAUNCHPOINT TECHNOLOGIES, INC. (Goleta, California) |
| ASSIGNEE(S) | LAUNCHPOINT TECHNOLOGIES, INC. (Goleta, California) |
| INVENTOR(S) | Michael Richard Ricci (Camarillo, California); Jonathan Gordon Sugar (Ventura, California); Bradley Evan Paden (Goleta, California); David Brian Paden (Goleta, California) |
| ABSTRACT | An axial flux brushless permanent magnet electrical machine having a stator and at least one rotor. The rotor includes a Halbach array of magnets with at least four magnets per magnetic cycle. The rotor magnets are contained within pockets in the rotor. The pockets are formed with magnet pocket walls being radial walls, active surface walls, and/or inactive surface walls where the walls retain the magnets within the pockets. |
| FILED | Wednesday, October 24, 2018 |
| APPL NO | 16/169043 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 1/30 (20130101) H02K 1/2793 (20130101) H02K 21/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10466754 | Eastep et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Jonathan M. Eastep (Portland, Oregon); Ilya Sharapov (San Jose, California); Richard J. Greco (West Linn, Oregon); Steve S. Sylvester (Hillsboro, Oregon); David N. Lombard (Rossmoor, California) |
| ABSTRACT | Systems and methods may provide a set of networked computational resources such as nodes that may be arranged in a hierarchy. A hierarchy of performance balancers receives performance samples from the computational resources beneath them and uses the performance samples to conduct a statistical analysis of variations in their performance. In one embodiment, the performance balancers steer power from faster resources to slower resources in order to enhance their performance, including in parallel processing. |
| FILED | Friday, December 26, 2014 |
| APPL NO | 14/583237 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 1/26 (20130101) Original (OR) Class G06F 1/324 (20130101) G06F 1/3203 (20130101) G06F 9/5061 (20130101) G06F 9/5094 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/22 (20180101) Y02D 10/126 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10467183 | Fleming, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kermin Fleming, Jr. (Hudson, Massachusetts); Simon C. Steely, Jr. (Hudson, New Hampshire); Kent D. Glossop (Merrimack, New Hampshire) |
| ABSTRACT | Methods and apparatuses relating to pipelined runtime services in spatial arrays are described. In one embodiment, a processor includes processing elements; an interconnect network between the processing elements; a first configuration controller coupled to a first subset of the processing elements; and a second configuration controller coupled to a second, different subset of the processing elements, the first configuration controller and the second configuration controller are to configure the first subset and the second, different subset according to configuration information for a first context, and, for a context switch, the first configuration controller is to configure the first subset according to configuration information for a second context after pending operations of the first context are completed in the first subset and block second context dataflow into the second, different subset's input from the first subset's output until pending operations of the first context are completed in the second, different subset. |
| FILED | Saturday, July 01, 2017 |
| APPL NO | 15/640538 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 15/80 (20130101) G06F 15/825 (20130101) G06F 15/7875 (20130101) G06F 15/7878 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10469347 | Eastep et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Jonathan M. Eastep (Portland, Oregon); Eric R. Borch (Fort Collins, Colorado) |
| ABSTRACT | Systems, apparatuses and methods may provide for a plurality of node-level agents, wherein each node-level agent aggregates network statistics information from a plurality of probes associated with a communications interface. Additionally, one or more job-level agents may be communicatively coupled to the plurality of node-level agents, wherein each job-level agent aggregates network statistics information from two or more of the node-level agents. Moreover, a system-level agent may be communicatively coupled to the job-level agent(s). The system-level agent may generate a power model based on aggregated network statistics information from the job-level agent(s) and propagate the power model to the node-level agents via the job-level agent(s). |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/081444 |
| ART UNIT | 2445 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/142 (20130101) H04L 43/08 (20130101) Original (OR) Class H04L 43/12 (20130101) H04L 43/045 (20130101) H04L 47/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10469397 | Fleming et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kermin Fleming (Hudson, Massachusetts); Kent D. Glossop (Merrimack, New Hampshire); Simon C. Steely, Jr. (Hudson, New Hampshire) |
| ABSTRACT | Systems, methods, and apparatuses relating to configurable network-based dataflow operator circuits are described. In one embodiment, a processor includes a spatial array of processing elements, and a packet switched communications network to route data within the spatial array between processing elements according to a dataflow graph to perform a first dataflow operation of the dataflow graph, wherein the packet switched communications network further comprises a plurality of network dataflow endpoint circuits to perform a second dataflow operation of the dataflow graph. |
| FILED | Saturday, July 01, 2017 |
| APPL NO | 15/640540 |
| ART UNIT | 2463 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/72 (20130101) H04L 47/10 (20130101) H04L 47/62 (20130101) Original (OR) Class H04L 49/254 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 10464065 | Selden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ANDE Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | ANDE Corporation (Waltham, Massachusetts) |
| INVENTOR(S) | Richard F. Selden (Lincoln, Massachusetts); Eugene Tan (Arlington, Massachusetts) |
| ABSTRACT | A self-contained apparatus for isolating nucleic acid, cell lysates and cell suspensions from unprocessed samples apparatus, to be used with an instrument, includes at least one input, and: (i) a macrofluidic component, including a chamber for receiving an unprocessed sample from a collection device and at least one filled liquid purification reagent storage reservoir; and (ii) a microfluidic component in communication with the macrofluidic component through at least one microfluidic element, the microfluidic component further comprising at least one nucleic acid purification matrix; and (iii) at least one interface port to a drive mechanism on the instrument for driving said liquid purification reagent, through the microfluidic element and the nucleic acid purification matrix, wherein the only inputs to the apparatus are through the chamber and the interface port to the drive mechanism. |
| FILED | Monday, October 03, 2016 |
| APPL NO | 15/284023 |
| ART UNIT | 1799 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5029 (20130101) B01L 3/50825 (20130101) B01L 3/502715 (20130101) B01L 3/502753 (20130101) Original (OR) Class B01L 7/52 (20130101) B01L 2200/16 (20130101) B01L 2200/027 (20130101) B01L 2300/087 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) B01L 2300/0887 (20130101) B01L 2400/043 (20130101) B01L 2400/0487 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/101 (20130101) C12N 15/1003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10465241 | Shin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELEAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Giwon Shin (Stanford, California); Billy Tsz Cheong Lau (Palo Alto, California); HoJoon Lee (Stanford, California); Hanlee P. Ji (Stanford, California) |
| ABSTRACT | A method for analyzing short tandem repeats (STRs) is described herein. In some embodiments, the method comprises: separately digesting two portions of a genomic sample at sites that are upstream and downstream of an STR; fragmenting those products; ligating adaptors to the fragmentation products; selectively amplifying part of the top strand but not the bottom strand of the ligation products derived from the first portion, and part of the bottom strand but not the top strand of the ligation products derived from the second portion; sequencing at least some of the amplification products to produce a plurality of top strand reads and a plurality of bottom strand reads; and counting the number of STR repeats in a sequence read. A kit for performing the method is also provided. |
| FILED | Wednesday, June 08, 2016 |
| APPL NO | 15/177115 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2521/313 (20130101) C12Q 2525/191 (20130101) C12Q 2565/543 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10468743 | Huggins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Federal Bureau of Investigation, Dept. of Justice (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Federal Bureau of Investigation, Dept. of Justice (Washington, District of Columbia) |
| INVENTOR(S) | John Scott Huggins (Warrenton, Virginia) |
| ABSTRACT | A mast mountable antenna that is rugged, weather-tolerant, and unaffected by the antenna's mounting structure, while maintaining an electrical path for lightning surge currents. The mast mountable antenna generally includes a radiating conductor section, an impedance transformer section, a low inductance feed point, a mounting mast section, a mast isolating stub section, and an integral coaxial feed line. |
| FILED | Friday, January 06, 2017 |
| APPL NO | 15/399969 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/1228 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10466189 | Sciammarella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Federico M. Sciammarella (Chicago, Illinois); Joseph S. Santner (Munster, Indiana); Matthew J. Gonser (Steward, Illinois); Justin Whiting (Clarksburg, Maryland); Daniel Nikolov (Batavia, Illinois) |
| ASSIGNEE(S) | Board of Trustees of Northern Illinois University (DeKalb, Illinois) |
| INVENTOR(S) | Federico M. Sciammarella (Chicago, Illinois); Joseph S. Santner (Munster, Indiana); Matthew J. Gonser (Steward, Illinois); Justin Whiting (Clarksburg, Maryland); Daniel Nikolov (Batavia, Illinois) |
| ABSTRACT | A calorimeter head and an associated system are provided. The calorimeter head provides symmetric circumferential laminar flow parallel to the bottom plane of a substrate plate of the calorimeter head. The calorimeter head defines a cavity which employs multiple tangentially arranged inlets for receipt of a flow of coolant from a control unit of the system. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 15/493918 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/4826 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10466363 | Lombardi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GOVERNMENT OF UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| INVENTOR(S) | Michael A. Lombardi (Broomfield, Colorado) |
| ABSTRACT | A disciplined clock provides a disciplined time and a disciplined frequency synchronous with a reference clock. The disciplined clock includes: a time receiver to: receive a common view signal from the common view clock; and produce a receiver timing signal; a local clock to: receive a frequency correction; and produce a local timing signal; a time interval counter to: receive the receiver timing signal from the time receiver; receive the local timing signal from the lock clock; and determine a time difference between the receiver timing signal and the local timing signal; and a controller to: receive the time difference from the time interval counter; and communicate the frequency correction, based on the time difference, to the local clock. |
| FILED | Thursday, January 19, 2017 |
| APPL NO | 15/410080 |
| ART UNIT | 2462 — Multiplex and VoIP |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/14 (20130101) G01S 19/21 (20130101) G01S 19/235 (20130101) Original (OR) Class Radio-controlled Time-pieces G04R 40/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 10464044 | Zoican-Loebick |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| ASSIGNEE(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| INVENTOR(S) | Codruta Maria Zoican-Loebick (North Haven, Connecticut) |
| ABSTRACT | A process of removing a volatile organic compound (VOC) from a gaseous environment, involving contacting a gaseous feedstream containing one or more VOC's, such as an odoriferous compound, an irritant, a contaminant or pollutant, for example, formaldehyde, with a sorbent under conditions sufficient to reduce the concentration of the VOC's in the gaseous feedstream. The sorbent is comprised of a functionalized graphene prepared by amination of graphene oxide. The sorbent is regenerated by adsorbate desorption under mild conditions of air flow. The process can be run through multiple adsorption-desorption cycles in a single fixed bed or swing bed configuration, and is applicable to purifying indoor air and ventilation air as well as reducing pollutants in industrial waste gas streams. |
| FILED | Monday, May 01, 2017 |
| APPL NO | 15/582813 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/04 (20130101) B01D 2253/20 (20130101) B01D 2253/306 (20130101) B01D 2257/206 (20130101) B01D 2257/708 (20130101) B01D 2259/40086 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/22 (20130101) Original (OR) Class B01J 20/28061 (20130101) B01J 20/28064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10464833 | Yeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Daniel H. Yeh (Tampa, Florida); George H. Dick (New Port Richey, Florida); Robert A. Bair (Tampa, Florida); Onur Y. Ozcan (Tampa, Florida); Jorge Luis Calabria (Land O'Lakes, Florida) |
| ABSTRACT | In one embodiment, a dilute wastewater treatment system includes a separation subsystem configured to receive dilute wastewater and separate it into a product stream containing a low concentration of organic material and a reject stream containing a high concentration of organic material, and a conversion subsystem configured to receive the reject stream from the separation subsystem and anaerobically treat the reject stream to break down the organic material and separate it from water within the reject stream. |
| FILED | Saturday, March 05, 2016 |
| APPL NO | 15/547820 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/08 (20130101) B01D 61/18 (20130101) B01D 61/142 (20130101) B01D 61/145 (20130101) B01D 61/147 (20130101) B01D 2311/06 (20130101) B01D 2311/06 (20130101) B01D 2311/08 (20130101) B01D 2311/08 (20130101) B01D 2311/2642 (20130101) B01D 2311/2642 (20130101) B01D 2311/2676 (20130101) B01D 2311/2688 (20130101) B01D 2311/2688 (20130101) B01D 2317/02 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/32 (20130101) C02F 1/76 (20130101) C02F 1/385 (20130101) C02F 1/444 (20130101) C02F 1/4674 (20130101) C02F 3/322 (20130101) C02F 3/1226 (20130101) C02F 3/2853 (20130101) Original (OR) Class C02F 2101/16 (20130101) C02F 2101/105 (20130101) C02F 2103/002 (20130101) C02F 2103/005 (20130101) C02F 2209/001 (20130101) C02F 2209/08 (20130101) C02F 2209/42 (20130101) C02F 2303/02 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 10/15 (20150501) Y02W 10/37 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10464963 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | STEPHEN F. AUSTIN STATE UNIVERSITY (Nacogdoches, Texas) |
| ASSIGNEE(S) | Stephen F. Austin State University (Nacogdoches, Texas) |
| INVENTOR(S) | Shiyou Li (Nacogdoches, Texas); Ping Wang (Nacogdoches, Texas); Guangrui Deng (Nacogdoches, Texas); Wei Yuan (Nacogdoches, Texas); Zushang Su (Nacogdoches, Texas) |
| ABSTRACT | In some embodiments, the compositions and methods relate to compounds isolated from plants in the Salviniaceae family, pharmaceutical compositions comprising the same, and methods of using the same. |
| FILED | Thursday, October 05, 2017 |
| APPL NO | 15/725421 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/05 (20130101) A61K 31/11 (20130101) A61K 31/11 (20130101) A61K 31/122 (20130101) A61K 31/122 (20130101) A61K 31/7048 (20130101) A61K 31/7048 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 39/17 (20130101) C07C 47/57 (20130101) C07C 49/737 (20130101) C07C 49/747 (20130101) C07C 49/755 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 17/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10467556 | Klabjan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Diego Klabjan (Deerfield, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Diego Klabjan (Deerfield, Illinois) |
| ABSTRACT | Certain examples provide systems and methods to identify placement for an electric charging station infrastructure. Certain examples provide systems and methods to generate a deployment plan for one or more electric vehicle charging stations. An example method includes gathering data for a specified geographic area and forecasting a demand for electric vehicles for the specified area. The example method includes modeling driving patterns in the specified area using available data and improving a charging infrastructure model based on the driving pattern and demand forecast information for the specified area. The example method includes generating and providing a recommendation regarding an electric vehicle charging infrastructure and deployment strategy for the specified area based on the improved charging infrastructure model. |
| FILED | Thursday, February 09, 2012 |
| APPL NO | 13/369855 |
| ART UNIT | 2122 — AI & Simulation/Modeling |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 53/63 (20190201) B60L 53/65 (20190201) B60L 2260/50 (20130101) B60L 2260/54 (20130101) Computer Systems Based on Specific Computational Models G06N 5/00 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/721 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7005 (20130101) Y02T 10/7072 (20130101) Y02T 90/14 (20130101) Y02T 90/121 (20130101) Y02T 90/128 (20130101) Y02T 90/163 (20130101) Y02T 90/169 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/126 (20130101) Y04S 30/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10463781 | Vidovich |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Chicago, Illinois); The US Government Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The US Government Represented by the Department of Veterans Affairs (Washington, District of Columbia); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Chicago, Illinois) |
| INVENTOR(S) | Mladen I. Vidovich (Chicago, Illinois) |
| ABSTRACT | The present invention is directed to a multi-angulated catheter and methods of using the multi-angulated catheter. The multi-angulated catheter is so dimensioned as to facilitate accessing the left ventricle from an arm of a patient. The multi-angulated catheter generally includes in order: (a) a coiled end; (b) a first straight portion having a first straight portion length; (c) a first shaft including a distal end connected to the first straight portion and a proximal end opposite the distal end, the first shaft and the first straight portion defining a first obtuse angle, the first shaft having a first shaft length; and (d) a second shaft connected to the first shaft on said proximal end. The catheter is flexible so as to afford being straightened when it is advanced over a guide wire. The catheter resiliently returns to a multi-angulated position after the guide wire is withdrawn. |
| FILED | Thursday, December 20, 2012 |
| APPL NO | 13/722511 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/007 (20130101) Original (OR) Class A61M 25/0041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 10466149 | Weling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triton Systems, Inc. (Chelmsford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aniruddha Weling (Framingham, Massachusetts); Tyson Lawrence (Cambridge, Massachusetts); Ken Mahmud (Sudbury, Massachusetts); James Burgess (Ringgold, Georgia); Leonid Krasnobaev (Framingham, Massachusetts); Joerg Lahann (Ann Arbor, Michigan) |
| ABSTRACT | A chemical sensing system includes a substrate material, a detector capable of indicating a presence of a target compound, gas, or vapor, and a heater for rapidly releasing compounds, gases and vapors from the substrate material. The substrate material acts to concentrate the compounds, gases, and vapors from a sample area for improved detection by the detector. |
| FILED | Tuesday, August 05, 2014 |
| APPL NO | 14/452398 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) G01N 1/405 (20130101) Original (OR) Class G01N 33/0057 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/25875 (20150115) Y10T 436/173076 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10466119 | Campbell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NextInput, Inc. (San Jose, California) |
| ASSIGNEE(S) | NEXTINPUT, INC. (Mountain View, California) |
| INVENTOR(S) | Ian Campbell (San Jose, California); Ryan Diestelhorst (San Jose, California); Dan Benjamin (San Jose, California); Steven S. Nasiri (Los Altos Hills, California) |
| ABSTRACT | An example MEMS force sensor is described herein. The MEMS force sensor can include a cap for receiving an applied force and a sensor bonded to the cap. A trench and a cavity can be formed in the sensor. The trench can be formed along at least a portion of a peripheral edge of the sensor. The cavity can define an outer wall and a flexible sensing element, and the outer wall can be arranged between the trench and the cavity. The cavity can be sealed between the cap and the sensor. The sensor can also include a sensor element formed on the flexible sensing element. The sensor element can change an electrical characteristic in response to deflection of the flexible sensing element. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/178976 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/18 (20130101) Original (OR) Class G01L 1/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10467447 | Kozicki |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael N. Kozicki (Phoenix, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Michael N. Kozicki (Phoenix, Arizona) |
| ABSTRACT | The disclosure features dendritic tags, and methods and systems for fabricating and using such tags. The methods can include obtaining at least one image of a dendritic tag attached to an article, analyzing the at least one image to identify a set of features associated with the dendritic tag, and comparing the set of features to stored information to identify the article. |
| FILED | Friday, July 26, 2019 |
| APPL NO | 16/523223 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/06 (20130101) G02B 21/365 (20130101) G02B 27/286 (20130101) Electric Digital Data Processing G06F 16/51 (20190101) G06F 16/9554 (20190101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1099 (20130101) Original (OR) Class G06K 9/46 (20130101) G06K 9/00147 (20130101) G06K 9/00577 (20130101) G06K 9/2027 (20130101) G06K 9/4671 (20130101) G06K 9/6202 (20130101) G06K 19/086 (20130101) G06K 19/06046 (20130101) G06K 19/07749 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/12 (20170101) G06T 2207/10056 (20130101) G06T 2207/30024 (20130101) Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 5/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3278 (20130101) H04L 2209/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10465165 | Cho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); New Jersey Institute of Technology (Newark, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey); NEW JERSEY INSTITUTE OF TECHNOLOGY (Newark, New Jersey) |
| INVENTOR(S) | Cheul Cho (Whippany, New Jersey); Steven Levison (Cedar Grove, New Jersey); Nolan Skop (Succasunna, New Jersey); Frances Calderon (Livingston, New Jersey); Chirag Gandhi (Mamaroneck, New York) |
| ABSTRACT | The present invention provides a multifunctional 2-D and 3-D matrix for propagation of stem cells. In particular, a chitosan-based biomaterial scaffold is engineered to promote CNS regeneration from primitive neural precursors by stabilizing a recombinant protein, fibroblast growth factor to preserve the cardinal properties of stem cells. The matrix, is further modified by the addition of either the extracellular matrix protein fibronectin or the small peptide RGD or IKVAV. A method to manufacture an injectable multifunctional microsphere scaffold is also disclosed that is suitable as a vehicle for cell transplantation to repair traumatic brain injuries. |
| FILED | Tuesday, January 28, 2014 |
| APPL NO | 14/763944 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0085 (20130101) A61K 9/5078 (20130101) A61K 35/28 (20130101) A61K 35/30 (20130101) A61K 35/51 (20130101) A61K 35/545 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0623 (20130101) Original (OR) Class C12N 2501/115 (20130101) C12N 2533/52 (20130101) C12N 2533/72 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 05, 2019.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20191105.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page