FedInvent™ Patents
Patent Details for Tuesday, November 12, 2019
This page was updated on Monday, March 27, 2023 at 05:56 AM GMT
Department of Health and Human Services (HHS)
| US 10470445 | Bial et al. |
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| FUNDED BY |
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| APPLICANT(S) | YECURIS CORPORATION (Tigard, Oregon) |
| ASSIGNEE(S) | Yecuris Corporation (Tigard, Oregon) |
| INVENTOR(S) | John R. Bial (Portland, Oregon); Elizabeth M. Wilson (Tualatin, Oregon); Aron M. Geurts (Milwaukee, Wisconsin) |
| ABSTRACT | Described herein are rats with a hepatic deficiency comprising decreased function, activity, or expression of an enzyme in the tyrosine catabolic pathway (such as fumarylacetoacetate hydrolase), and methods of using the same for in vivo engraftment and expansion of heterologous hepatocytes, such as human hepatocytes, analysis of human liver disease, and analysis of xenobiotics. Also disclosed is the use of immunodeficient rats for the engraftment and expansion of heterologous hepatocytes. |
| FILED | Thursday, May 19, 2016 |
| APPL NO | 15/159200 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) Original (OR) Class A01K 67/0278 (20130101) A01K 2207/12 (20130101) A01K 2207/15 (20130101) A01K 2217/00 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) A01K 2267/0387 (20130101) Peptides C07K 14/7155 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) C12N 9/6462 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 304/21073 (20130101) C12Y 307/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10470675 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Xinyu Zhang (Madison, Wisconsin); Teng Wei (Madison, Wisconsin); Shu Wang (Chicago, Illinois); Anfu Zhou (Beijing, China PRC) |
| ABSTRACT | A wireless vibrometer employs an antenna array to significantly boost the signal-to-noise ratio of faint received signals twin small objects vibrating at acoustic frequencies. This technique may be used to provide an improved physiological monitor (such as a pulse detector) or for long-range eavesdropping using the emitted power from a cell phone or the like. |
| FILED | Friday, June 17, 2016 |
| APPL NO | 15/185692 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/02444 (20130101) Original (OR) Class Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/00 (20130101) Secret Communication; Jamming of Communication H04K 3/25 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10470676 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Danny J J Wang (Oak Park, California); Lirong Yan (Los Angeles, California); Hee Kwon Song (Moorestown, New Jersey) |
| ABSTRACT | A method for non-contrast enhanced 4D time resolved dynamic magnetic resonance angiography using arterial spin labeling of blood water as an endogenous tracer and a multiphase balanced steady state free precession readout is presented. Imaging can be accelerated with dynamic golden angle radial acquisitions and k-space weighted imaging contrast (KWIC) image reconstruction and it can be used with parallel imaging techniques. Quantitative tracer kinetic models can be formed allowing cerebral blood volume, cerebral blood flow and mean transit time to be estimated. Vascular compliance can also be assessed using 4D dMRA by synchronizing dMRA acquisitions with the systolic and diastolic phases of the cardiac cycle. |
| FILED | Tuesday, May 26, 2015 |
| APPL NO | 14/721546 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0263 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) G01R 33/4818 (20130101) G01R 33/4824 (20130101) G01R 33/4828 (20130101) G01R 33/5601 (20130101) G01R 33/5611 (20130101) G01R 33/5614 (20130101) G01R 33/5635 (20130101) G01R 33/56333 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10470680 | Durand et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Dominique M. Durand (Solon, Ohio); Brian Wodlinger (Cleveland Heights, Ohio) |
| ABSTRACT | Systems and methods are provided for controlling an entity in response to activity in a peripheral nerve comprising a plurality of fascicles. A multicontact electrode assembly is configured to record activity from the peripheral nerve. A processing component includes a sensor mapping component configured to quantify activity associated with a proper subset of the plurality of fascicles, an evaluation component configured to determine an adjustment of the status of the controlled entity from the quantified activity of the proper subset of the plurality of fascicles, and a controller configured to provide a control signal, representing the adjustment of the status of the controlled entity, to the controlled entity. |
| FILED | Wednesday, March 15, 2017 |
| APPL NO | 15/459349 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/04001 (20130101) Original (OR) Class A61B 5/4029 (20130101) A61B 5/4041 (20130101) A61B 5/4064 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) A61N 1/36003 (20130101) A61N 1/36103 (20130101) Electric Digital Data Processing G06F 17/5009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471016 | Mooney et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David J. Mooney (Sudbury, Massachusetts); David A. Weitz (Bolton, Massachusetts); Stefanie Utech (Erlangen, Germany); Radivoje Prodanovich (Belgrade, Serbia); Esther Amstad (Lausanne, Switzerland); Raluca Ostafe (Aachen, Germany); Angelo S. Mao (Somerville, Massachusetts); Connie Chang Wilking (Bozeman, Montana); Huanan Wang (Dalian, China PRC) |
| ABSTRACT | The invention relates to microparticles comprising a crosslinked gel and methods for making and using same. |
| FILED | Thursday, March 08, 2018 |
| APPL NO | 15/915686 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1652 (20130101) A61K 9/5036 (20130101) Original (OR) Class A61K 9/5089 (20130101) A61K 35/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471023 | Andersen et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF BRITISH COLUMBIA (Vancouver, Canada); BRITISH COLUMBIA CANCER AGENCY BRANCH (Vancouver, Canada) |
| ASSIGNEE(S) | British Columbia Cancer Agency Branch (Vancouver, Canada); The University of British Columbia (Vancouver, Canada) |
| INVENTOR(S) | Raymond John Andersen (Vancouver, Canada); Kunzhong Jian (Vancouver, Canada); Marianne Dorothy Sadar (West Vancouver, Canada); Nasrin R. Mawji (Burnaby, Canada); Carmen Adriana Banuelos (Richmond, Canada) |
| ABSTRACT | Compounds having a structure of Formula I, or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, L1, L2, L3, X, a, b, c, n, and m are as defined herein, are provided. Uses of such compounds for modulating androgen receptor activity and uses as therapeutics as well as methods for treatment of subjects in need thereof, including prostate cancer are also provided. |
| FILED | Friday, March 11, 2016 |
| APPL NO | 15/557726 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/09 (20130101) Original (OR) Class A61K 31/047 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 43/23 (20130101) C07C 43/225 (20130101) C07C 69/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471047 | Prossnitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Eric R. Prossnitz (Albuquerque, New Mexico); Geetanjali Sharma (Albuquerque, New Mexico) |
| ABSTRACT | The current invention is in the field of molecular biology/pharmacology and provides methods of using compounds that modulate the effects of GPR30/GPER for treating obesity and diabetes (preferably agonists) as well as disease states and/or conditions that result from excessive formation of reactive oxygen species (preferably antagonists). These compounds may function as agonists and/or antagonists of the disclosed estrogen receptor and/or modulate the expression/upregulation of nox and nox-associated reactive oxygen species (ROS). |
| FILED | Wednesday, July 11, 2018 |
| APPL NO | 16/033008 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/16 (20130101) A61K 31/435 (20130101) A61K 31/436 (20130101) Original (OR) Class A61K 31/437 (20130101) A61K 31/4355 (20130101) A61K 31/7088 (20130101) A61K 38/28 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471059 | Bennett et al. |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Anton Bennett (Wilton, Connecticut); Jae-Sung Yi (Hamden, Connecticut) |
| ABSTRACT | The present invention provides compositions and methods of inhibiting tyrosine phosphorylation. In one aspect, a composition comprising a low-dosage tyrosine kinase inhibitor, where the low-dosage tyrosine kinase inhibitor decreases tyrosine phosphorylation, is provided. In another aspect, a method for treating cardiovascular disease or condition associated with a RASopathy having aberrant protein tyrosine phosphorylation is described. Methods for treating congenital heart disease associated with Noonan or Noonan syndrome with multiple lentigines and decreasing aberrant levels of Protein Zero-Related (PZR) tyrosyl phosphorylation are also described. |
| FILED | Tuesday, January 26, 2016 |
| APPL NO | 15/544401 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471061 | Boxer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Matthew B. Boxer (Frederick, Maryland); Martin J. Walsh (Carmel, Indiana); Li Liu (Germantown, Maryland); Cordelle D. Tanega (Rockville, Maryland); Min Shen (Boyds, Maryland); Kent Lai (Salt Lake City, Utah); Manshu Tang (Salt Lake City, Utah); Douglas S. Auld (Beverly, Massachusetts) |
| ABSTRACT | Disclosed are inhibitors of human galactokinase of formula (I) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal. Formula (I). |
| FILED | Friday, October 05, 2018 |
| APPL NO | 16/152735 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/517 (20130101) Original (OR) Class A61K 31/527 (20130101) Heterocyclic Compounds C07D 403/12 (20130101) C07D 413/12 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) C07D 491/107 (20130101) C07D 493/10 (20130101) C07D 495/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471080 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Peixin Yang (Woodstock, Maryland); E. Albert Reece (Lutherville, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Peixin Yang (Woodstock, Maryland); E. Albert Reece (Lutherville, Maryland) |
| ABSTRACT | Maternal diabetes suppresses autophagy in neuroepithelial cells of the developing neural tube which leads to neural tube defect formation. Trehalose treatment reversed autophagy impairment and prevented neural tube defects in diabetic pregnancies. Trehalose resolved homeostatic imbalance by correcting mitochondrial defects, dysfunctional proteins, ER stress, apoptosis, and delayed neurogenesis in the neural tubes exposed to hyperglycemia. Methods of using trehalose as an intervention against hyperglycemia-induced neural tube defects are provided herein. |
| FILED | Friday, May 24, 2013 |
| APPL NO | 13/901784 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Brushes A46B 15/0093 (20130101) A46B 2200/1046 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/7016 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471082 | Padmanabhan et al. |
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| FUNDED BY |
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| APPLICANT(S) | GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Radhakrishnan Padmanabhan (Bethesda, Maryland); Tadahisa Teramoto (Potomac, Maryland); Mark Manzano (Chicago, Illinois) |
| ABSTRACT | Methods of treating or preventing a Flavivirus infection in a subject are provided. The methods comprise administering to the subject a therapeutically effective amount of a Flavivirus inhibitor, e.g., a Flavivirus protease inhibitor. These methods are useful in treating and/or preventing Flavivirus infections such as, for example, West Nile Virus, Dengue Virus, and Japanese Encephalitis Virus. Methods of inhibiting a Flavivirus protease in a cell are also provided. |
| FILED | Wednesday, October 23, 2013 |
| APPL NO | 14/437434 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/44 (20130101) A61K 31/352 (20130101) A61K 31/415 (20130101) A61K 31/426 (20130101) A61K 31/519 (20130101) A61K 31/4178 (20130101) A61K 31/7032 (20130101) Original (OR) Class A61K 31/7034 (20130101) A61K 45/06 (20130101) Technologies for Adaptation to Climate Change Y02A 50/385 (20180101) Y02A 50/389 (20180101) Y02A 50/393 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471086 | Merali et al. |
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| APPLICANT(S) | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Temple University Of The Commonwealth System Of Higher Education (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Salim Merali (Bryn Mawr, Pennsylvania); Steven G. Kelsen (Rydal, Pennsylvania); Carlos A. Barrero (Philadelphia, Pennsylvania) |
| ABSTRACT | The methods described herein are based on the discovery that the plasma level of a panel of specific proteins differs between two subject populations: 1) subjects at risk for chronic obstructive pulmonary disease (“COPD”) but not manifesting clinical symptoms of COPD; and 2) subjects having very severe COPD. The difference in plasma levels is statistically significant for each protein. The identification of these proteins thus facilitates susceptibility detection, early disease detection, disease severity assessment, disease progression monitoring, and therapy efficacy monitoring. |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/081073 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/365 (20130101) A61K 31/7072 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/50 (20130101) G01N 2800/56 (20130101) G01N 2800/60 (20130101) G01N 2800/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471087 | Hirano et al. |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York); Fundació Hospital Universitari Vall d'Hebron-Institut de Recerca (Barcelona, Spain) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York); Fundació Hospital Universitari Vall d'Hebron-Institut de Recerca (Barcelona, Spain) |
| INVENTOR(S) | Michio Hirano (New York, New York); Caterina Garone (Cambridge, United Kingdom); Ramon Marti (Barcelona, Spain) |
| ABSTRACT | The invention relates generally to a pharmacological therapy for human genetic diseases, specifically those characterized by unbalance nucleotide pools, more specifically mitochondrial DNA depletion syndromes, and more specifically, thymidine kinase 2 (TK2) deficiency. The pharmacological therapy involves the administration of at least one deoxynucleoside, or mixtures thereof. For the treatment of TK2 deficiency, the pharmacological therapy involves the administration of either deoxythymidine (dT) or deoxycytidine (dC), or mixtures thereof. This administration of deoxynucleosides is applicable to other disorders of unbalanced nucleotide pools, especially those found in mitochondrial DNA depletion syndrome. |
| FILED | Friday, June 17, 2016 |
| APPL NO | 15/736092 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/7068 (20130101) A61K 31/7072 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471098 | Katz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Prospect CharterCare RWMC, LLC (Providence, Rhode Island) |
| ASSIGNEE(S) | PROSPECT CHARTERCARE RWMC, LLC (Providence, Rhode Island) |
| INVENTOR(S) | Steven C. Katz (Providence, Rhode Island); Richard Junghans (Boston, Massachusetts) |
| ABSTRACT | Disclosed herein are compositions and methods for the treatment of liver metastases in a subject. The methods include hepatic arterial infusion (HAI) of chimeric antigen receptor modified T cells (CAR-T) which are highly specific for tumor antigens such as carcinoembryonic antigen (CEA). The HAI method is optimized to maximize exposure of the modified cells to the metastatic cells while minimizing exposure to healthy cells. The methods include co-administration of a second therapeutic agent, such as IL-2. |
| FILED | Thursday, April 14, 2016 |
| APPL NO | 15/099370 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/17 (20130101) Original (OR) Class A61K 38/2013 (20130101) A61K 38/2013 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471103 | Sackstein |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Robert Sackstein (Sudbury, Massachusetts) |
| ABSTRACT | Methods of treatment are provided herein, including administration of a population cells modified to enforce expression of an E-selectin and/or an L-selectin ligand, the modified cell population having a cell viability of at least 70% after a treatment to enforce such expression. |
| FILED | Tuesday, December 29, 2015 |
| APPL NO | 14/982863 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) A61K 35/28 (20130101) A61K 35/30 (20130101) Original (OR) Class A61K 35/32 (20130101) A61K 35/33 (20130101) A61K 35/34 (20130101) A61K 35/35 (20130101) A61K 35/37 (20130101) A61K 35/42 (20130101) A61K 35/407 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0006 (20130101) C12N 2501/724 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471118 | Palczewski et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Krzysztof Palczewski (Cleveland, Ohio); Zheng-Rong Lu (Cleveland, Ohio) |
| ABSTRACT | A pharmaceutical composition includes a retinylamine derivative having the following formula (I): where R1 is an amino acid residue, a dipeptide or a tripeptide that is linked to the retinylamine by an amide bond. |
| FILED | Monday, June 01, 2015 |
| APPL NO | 15/315207 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/16 (20130101) A61K 31/40 (20130101) A61K 31/165 (20130101) A61K 38/05 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/65 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471137 | Barouch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Janssen Vaccines and Prevention B.V. (Leiden, Netherlands); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Janssen Vaccines and Prevention B.V. (Leiden, Netherlands); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Dan Barouch (Newton, Massachusetts); Johanna Schuitemaker (Amstelveen, Netherlands); Maria Grazia Pau (Leiden, Netherlands); Danielle Van Manen (Leiden, Netherlands); Frank Tomaka (Titusville, New Jersey); Jennifer Anne Hendriks (Poeldijk, Netherlands) |
| ABSTRACT | Compositions, vaccines and methods for inducing protective immunity against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more viral expression vectors and an isolated antigenic polypeptide induced strong protective immunity against infections by one or multiple clades of HIV. |
| FILED | Wednesday, May 02, 2018 |
| APPL NO | 15/968834 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 2039/575 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2710/10043 (20130101) C12N 2710/24143 (20130101) C12N 2740/16034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471139 | David et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | The University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Sunil Abraham David (Lawrence, Kansas); Euna Yoo (Lawrence, Kansas); Nikunj Shukla (Lawrence, Kansas); Alex Christopher Salyer (Lawrence, Kansas); Mallesh Beesu (Lawrence, Kansas); Subbalakshmi S. Malladi (Lawrence, Kansas); Cassandra Jones (Lawrence, Kansas) |
| ABSTRACT | Compounds described herein can be used for therapeutic purposes. The compounds can be TLR agonists, such as TLR7 or TLR8 agonists. The compounds can be included in pharmaceutical compositions and used for therapies were being a TLR agonist is useful. The pharmaceutical compositions can include any ingredients, such as carries, diluents, excipients, fillers or the like that are common in pharmaceutical compositions. The compounds can be those illustrated or described herein as well as derivative thereof, prodrug thereof, salt thereof, or stereoisomer thereof, or having any chirality at any chiral center, or tautomer, polymorph, solvate, or combinations thereof. As such, the compounds can be used as adjuvants in vaccines as well as for other therapeutic purposes described herein. The compounds can have any one of the formulae. Examples of the compounds can be reviewed in Table 1 and Table A1 for activates. |
| FILED | Friday, August 15, 2014 |
| APPL NO | 14/909967 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Original (OR) Class A61K 2039/55511 (20130101) Heterocyclic Compounds C07D 235/30 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471142 | Basta et al. |
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| FUNDED BY |
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| APPLICANT(S) | Milan Basta (Potomac, Maryland); Xinzhi Chen (Wexford, Pennsylvania); Mark Mattson (Bel Air, Maryland) |
| ASSIGNEE(S) | CSL BEHRING GMBH (Marburg, Germany); THE GOVERNMENT OF THE UNITED STATES OF AMERICA (Rockville, Maryland) |
| INVENTOR(S) | Milan Basta (Potomac, Maryland); Xinzhi Chen (Wexford, Pennsylvania); Mark Mattson (Bel Air, Maryland) |
| ABSTRACT | Methods are disclosed for treating cerebral ischemia using a combination of C1-INH and immunoglobulin, such as human plasma derived immunoglobulin (IVIG). |
| FILED | Friday, September 21, 2012 |
| APPL NO | 14/346478 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/55 (20130101) A61K 38/55 (20130101) A61K 38/57 (20130101) A61K 39/39516 (20130101) Original (OR) Class A61K 39/39516 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471162 | Desogere et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Pauline Desogere (Cambridge, Massachusetts); Peter Caravan (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed herein are collagen-targeted imaging agents for positron emission tomography and related imaging methods using the collagen-targeted imaging agents. The collagen-targeted imaging agent is a cyclic polypeptide comprising a cyclic main body, wherein the cyclic main body comprises at least one S—S bond; at least two branches, wherein each of the at least two branches comprises at least three amino acids; and a linker, wherein the linker is capable of linking an imaging reporter. |
| FILED | Monday, June 22, 2015 |
| APPL NO | 15/320112 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 51/08 (20130101) Original (OR) Class Peptides C07K 14/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471163 | Loving et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Galen Loving (Berkeley, California); Peter D. Caravan (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are methods for determining the presence or absence of active thrombus formation using a linear polypeptide that binds fibrin upon cyclization. Also provided are compounds comprising linear polypeptide probes that are cyclized in the presence of protein disulfide isomerase. |
| FILED | Friday, September 12, 2014 |
| APPL NO | 14/917733 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/14 (20130101) A61K 49/0056 (20130101) A61K 51/08 (20130101) A61K 51/088 (20130101) Original (OR) Class Peptides C07K 7/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471408 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BioFire Diagnostics, LLC (Salt Lake City, Utah) |
| ASSIGNEE(S) | BioFire Diagnostics, LLC (Salt Lake City, Utah) |
| INVENTOR(S) | David E. Jones (Layton, Utah); Kirk Max Ririe (Salt Lake City, Utah); Thomas Charles Robbins (Salt Lake City, Utah); Elizabeth Doman Copene (Salt Lake City, Utah); Charles Benjamin Cox (Sandy, Utah) |
| ABSTRACT | Devices and methods are provided for spotting an array with fluid. Arrays produced by such methods are also provided. In one aspect of the invention, a spotter device for spotting a plurality of fluids into an array is described, the spotter device comprising a plurality of reservoirs provided in a first configuration, each reservoir holding its respective fluid, a print head having a plurality of positions provided in a second configuration, the second configuration being different from the first configuration, a plurality of tubes, each tube configured to provide fluid communication from a reservoir at a first end of the tube to a position in the print head at the second end of the tube, and a pump for pumping fluid through the tubes from the reservoir to the print head. |
| FILED | Thursday, January 05, 2017 |
| APPL NO | 15/399663 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/00313 (20130101) B01J 2219/00355 (20130101) B01J 2219/00376 (20130101) B01J 2219/00385 (20130101) B01J 2219/00585 (20130101) B01J 2219/00693 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0262 (20130101) B01L 3/0265 (20130101) B01L 2200/16 (20130101) B01L 2300/0861 (20130101) B01L 2300/1822 (20130101) B01L 2300/1827 (20130101) B01L 2400/0478 (20130101) B01L 2400/0487 (20130101) B01L 2400/0605 (20130101) B01L 2400/0616 (20130101) B01L 2400/0655 (20130101) B01L 2400/0677 (20130101) B01L 2400/0683 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471428 | Ramsey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | John Michael Ramsey (Chapel Hill, North Carolina); Laurent D. Menard (Raleigh, North Carolina); Michael A. Tycon (San Jose, California); Oscar A. McCrate (Carrboro, North Carolina) |
| ABSTRACT | Fluidic devices with a primary transport nanochannel(s) intersected by at least one nanoscale manifold for active control of capture, manipulation and transport of analyte molecules. The at least one manifold can be an array or network of nanochannels, nanoslits or nanoelectrodes joined to a common voltage or pressure source. A respective nanoscale manifold can be configured to allow for precise and active control of driving forces applied to the primary transport nanochannel(s) to drive molecular transport through the various regions along the transport nanochannel(s). The at least one manifold can generate monotonic force gradients with a limited or reduced number of independent input potentials and/or pressures applied to the device. |
| FILED | Wednesday, May 04, 2016 |
| APPL NO | 15/568980 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0896 (20130101) B01L 2400/0421 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 15/1484 (20130101) G01N 2015/0038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472346 | Wagner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Coporation (Boston, Massachusetts); The Regents of the University of California (Oakland, California); Steven L. Wagner (San Diego, California); William C. Mobley (La Jolla, California); Rudolph E. Tanzi (Hull, Massachusetts); Graham Johnson (Sanbornton, New Hampshire); Ronald Buckle (Delmar, New York); Nicholas Mayhew (Niskayuna, New York); Robert Jason Herr (Voorheesville, New York) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Steven L. Wagner (San Diego, California); William C. Mobley (La Jolla, California); Rudolph E. Tanzi (Hull, Massachusetts); Graham Johnson (Sanbornton, New Hampshire); Ronald Buckle (Delmar, New York); Nicholas Mayhew (Niskayuna, New York); Robert Jason Herr (Voorheesville, New York); Kevin D. Rynearson (La Mesa, California) |
| ABSTRACT | Provided herein are compounds and methods for treating a disorder associated with aberrant A3 peptide levels, including Alzheimer's disease. Provided herein are compositions and methods for treating a disorder associated with aberrant Aβ peptide levels, including AD. Provided herein are compounds of Formula (A) or a pharmaceutically acceptable salt thereof, wherein, L′ is selected from the group consisting of C(O), C(R1)(R2), substituted or unsubstituted —C2-6 alkylene-, and substituted or unsubstituted —C3-6 cycloalkylene. |
| FILED | Friday, October 30, 2015 |
| APPL NO | 15/522969 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class C07D 413/14 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472355 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | Texas Tech University System (Lubbock, Texas) |
| INVENTOR(S) | Ruiwen Zhang (Amarillo, Texas); Wei Wang (Amarillo, Texas) |
| ABSTRACT | An SP-141 compound is a novel small molecule that can serve as a molecular-targeted chemotherapeutic agent. In one embodiment, the labeled compound can comprise SP-141, which comprises 6-methoxy-1-(naphthalen-1-yl)-9 H-pyrido[3,4-b]indote. The compound inhibits expression of oncogenes such as the Mouse Double Minute 2 protein. The compound can bind directly to Mouse Double Minute 2 to inhibit cancer growth including breast cancer growth. |
| FILED | Friday, September 25, 2015 |
| APPL NO | 15/513882 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472372 | Ghosh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); National University Corporation Kumamoto University (Chuo-ku, Japan) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana); National University Corporation Kumamoto University (Chuo-ku, Kumamoto, Japan) |
| INVENTOR(S) | Arun K. Ghosh (West Lafayette, Indiana); Hiroaki Mitsuya (Kumamoto, Japan) |
| ABSTRACT | Various embodiments relate to a compound of the formula (I): wherein X, X1, R1—R4 and R7 are defined herein, as well as pharmaceutical compositions comprising compounds of the formula (I) and methods of treating an HIV infection comprising administering a therapeutically effective amount of one or more compounds of formula (I), or a pharmaceutical compositions comprising compounds of the formula (I), to a patient in need thereof. |
| FILED | Wednesday, August 17, 2016 |
| APPL NO | 15/753264 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 491/20 (20130101) C07D 493/04 (20130101) Original (OR) Class C07D 498/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6561 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472383 | Benner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steven A Benner (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven A Benner (Gainesville, Florida) |
| ABSTRACT | This invention claims aqueous compositions that comprise triphosphates of 2′-deoxynucleoside derivatives that have, instead of a 3′-OH moiety, a 3′-ONH2 moiety; wherein said compositions contain less than 0.5 mole percent contaminating triphosphate having a 3′-OH moiety, as well as processes for providing such compositions. The compositions further must contain insubstantial amounts of hydroxylamine. |
| FILED | Thursday, March 16, 2017 |
| APPL NO | 15/460475 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) Original (OR) Class C07H 19/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472391 | Wardenburg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois); SRI International (Menlo Park, California) |
| ASSIGNEE(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois); SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | Juliane Bubeck Wardenburg (Chicago, Illinois); Katherine Weh (Chicago, Illinois); Leyi Gong (Menlo Park, California) |
| ABSTRACT | Certain embodiments are directed to compositions and methods of inhibiting a pathogenic bacterial infection involving ADAM10, specifically a method for treating pore-forming toxin-inducted pathology caused by exposure to staphylococcus in a subject, comprising administering an effective amount of a ADAM10 inhibitor to a patient. The methods include treating pneumonia or inhibiting disruption to epithelial barrier in a subject, having or at risk of developing staphylococcal infection. |
| FILED | Friday, April 04, 2014 |
| APPL NO | 14/781962 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 38/00 (20130101) A61K 38/05 (20130101) A61K 45/06 (20130101) Peptides C07K 5/0202 (20130101) Original (OR) Class C07K 14/8146 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472397 | Federici et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brian A. Federici (Riverside, California); Dennis Bideshi (Corona, California); Hyun-Woo Park (Riverside, California); Robert Hice (Riverside, California); Tianyun Su (Riverside, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Brian A. Federici (Riverside, California); Dennis Bideshi (Corona, California); Hyun-Woo Park (Riverside, California); Robert Hice (Riverside, California); Tianyun Su (Riverside, California) |
| ABSTRACT | A chimeric protein comprising a cytolytic δ-endotoxin portion and a heterologous polypeptide portion is provided. Nucleic acids encoding the chimeric protein are also provided. In some cases, the chimeric protein can be expressed in parasporal inclusions of Bacillus thuringiensis. In certain cases, the cytolytic δ-endotoxin portion can include Cyt1Aa, and the heterologous portion can include an insecticidal polypeptide. The chimeric protein can be expressed in a suitable B. thuringiensi cell and purified as parasporal inclusions. Also provided is a method of controlling insects by exposing an insect to a chimerical insecticidal protein. |
| FILED | Monday, July 10, 2017 |
| APPL NO | 15/646062 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/02 (20130101) Peptides C07K 14/32 (20130101) C07K 14/325 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472398 | Klapoetke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of The University of Alberta (Edmonton, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of The University of Alberta (Edmonton, Alberta, Canada) |
| INVENTOR(S) | Nathan Klapoetke (Cambridge, Massachusetts); Brian Yichiun Chow (Cambridge, Massachusetts); Edward Boyden (Chestnut Hill, Massachusetts); Gane Ka-Shu Wong (Edmontn, Canada); Yongku Peter Cho (Cambridge, Massachusetts) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. |
| FILED | Monday, November 12, 2012 |
| APPL NO | 14/357635 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0661 (20130101) A61N 2005/0662 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) G01N 33/48728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472399 | Klapoetke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Alberta, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of The University of Alberta (Edmonton, Alberta, AB, Canada) |
| INVENTOR(S) | Nathan Klapoetke (Ashburn, Virginia); Brian Yichiun Chow (Cherry Hill, New Jersey); Edward Boyden (Chestnut Hill, Massachusetts); Gane Ka-Shu Wong (Edmonton, Canada); Yongku Peter Cho (Vernon, Connecticut) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/359875 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0661 (20130101) A61N 2005/0662 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) G01N 33/48728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472406 | Weiss |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Michael Weiss (Moreland Hills, Ohio) |
| ABSTRACT | A two-chain insulin analog contains Aspartic Acid at position B10 and penta-fluoro-Phenylalanine at position B24, optionally Histidine or Glutamic Acid at position A8, optionally additional substitutions or modifications at positions A13 and/or A14 and/or B28 and/or B29. The analog may be an analog of a mammalian insulin, such as human insulin, may optionally include (i) N-terminal deletion of one, two or three residues from the B chain, (ii) a mono-peptide or dipeptide C-terminal extension of the B-chain containing at least one acidic residue, and (iii) other modifications known in the art to enhance the stability of insulin. Formulations of the above analogs at successive strengths U-100 to U-1000 in soluble solutions at least pH value in the range 7.0-8.0 in the absence or presence of zinc ions at a molar ratio of 0.00-0.10 zinc ions per insulin analog monomer. |
| FILED | Wednesday, January 20, 2016 |
| APPL NO | 15/545189 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/62 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472412 | Dimitrov et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Fudan University (Shanghai, China PRC) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Fudan University (Shanghai, China PRC) |
| INVENTOR(S) | Dimiter S. Dimitrov (Frederick, Maryland); Weizao Chen (Frederick, Maryland); Tianlei Ying (Shanghai, China PRC) |
| ABSTRACT | The invention provides a construct comprising two or more fusion proteins of Formulas (I)-(IV): A-(optional linker)-C-(optional linker)-B (Formula I), B-(optional linker)-D-(optional linker)-E-(optional linker)-B (Formula II), A-(optional linker)-C (Formula III), and B-(optional linker)-D-(optional linker)-E (Formula IV), wherein A denotes an antibody or antibody fragment, B denotes a single domain CD4, C denotes an immunoglobulin light chain constant region D denotes an immunoglobulin heavy chain constant region, and E denotes an Fc region or a portion thereof that is optionally defucosylated. |
| FILED | Wednesday, December 16, 2015 |
| APPL NO | 15/561268 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/6803 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 14/70514 (20130101) C07K 16/1063 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/35 (20130101) C07K 2317/41 (20130101) C07K 2317/53 (20130101) C07K 2317/72 (20130101) C07K 2317/76 (20130101) C07K 2317/90 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/515 (20130101) C07K 2317/522 (20130101) C07K 2317/526 (20130101) C07K 2317/569 (20130101) C07K 2317/732 (20130101) C07K 2319/00 (20130101) C07K 2319/30 (20130101) C07K 2319/32 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472413 | Kaufmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sorrento Therapeutics, Inc. (San Diego, California) |
| ASSIGNEE(S) | SORRENTO THERAPEUTICS, INC. (San Diego, California) |
| INVENTOR(S) | Gunnar F. Kaufmann (San Diego, California); Heyue Zhou (San Diego, California); Guodi Lu (San Diego, California) |
| ABSTRACT | There is disclosed compositions and methods relating to or derived from anti-AIP2 antibodies. More specifically, there is disclosed fully human antibodies that bind AIP2, AIP2-binding fragments and derivatives of such antibodies, and AIP2-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having AIP2 related disorders or conditions. There is also disclosed a method to treat S. aureus infections by administering an anti-AIP2 antibody described herein. |
| FILED | Friday, March 17, 2017 |
| APPL NO | 15/462427 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1271 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472419 | Sabatos-Peyton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novartis AG (Basel, Switzerland); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Novartis AG (Basel, Switzerland); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Catherine Anne Sabatos-Peyton (Cambridge, Massachusetts); Barbara Brannetti (Basel, Switzerland); Alan S. Harris (Cambridge, Massachusetts); Thomas Huber (Basel, Switzerland); Thomas Pietzonka (Basel, Switzerland); Jennifer Marie Mataraza (Cambridge, Massachusetts); Walter A. Blattler (Brookline, Massachusetts); Daniel J. Hicklin (Montclair, New Jersey); Maximiliano Vasquez (Palo Alto, California); Rosemarie H. DeKruyff (Portola Valley, California); Dale T. Umetsu (Portola Valley, California); Gordon James Freeman (Brookline, Massachusetts); Tiancen Hu (Cambridge, Massachusetts); John A. Taraszka (Cambridge, Massachusetts); Fangmin Xu (Cambridge, Massachusetts) |
| ABSTRACT | Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders. |
| FILED | Tuesday, February 14, 2017 |
| APPL NO | 15/432819 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 2299/00 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/34 (20130101) C07K 2317/51 (20130101) C07K 2317/52 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/515 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472599 | Barbie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | David Barbie (Andover, Massachusetts); Amir Aref (Malden, Massachusetts); Thanh Barbie (Andover, Massachusetts); Russell W. Jenkins (Boston, Massachusetts); Kwok-kin Wong (Arlington, Massachusetts) |
| ABSTRACT | Provided herein are methods for culturing patient-derived tumor cell spheroids in a three-dimensional microfluidic device. The method comprises mincing primary tumor sample in a medium supplemented with serum; treating the minced primary tumor sample with a composition comprising an enzyme; collecting tumor spheroids having a diameter of 10 μm to 500 μm from the enzyme treated sample; suspending the tumor spheroids in biocompatible gel; and culturing the tumor spheroids in a three dimensional microfluidic device. Methods for identifying an agent for treating cancer and microfluidic devices that allow for the simultaneous exposure of the cultured patient-derived primary tumor cell spheroids to a treatment of choice and to control treatment are also provided. |
| FILED | Thursday, January 07, 2016 |
| APPL NO | 15/540346 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 2503/02 (20130101) C12N 2513/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472612 | Ingber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Donald E. Ingber (Boston, Massachusetts); Hyun Jung Kim (Brookline, Massachusetts) |
| ABSTRACT | The embodiments of the invention described herein relate to systems and methods for culturing and/or maintaining intestinal cells, tissues and/or organoids in vitro. The cells, tissues and/or organoids cultured according to the methods and systems described herein can mimic or reproduce natural intestinal epithelial structures and behavior as well as support co-culture of intestinal microflora. |
| FILED | Thursday, December 22, 2016 |
| APPL NO | 15/388171 |
| ART UNIT | 1799 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/20 (20130101) C12M 23/26 (20130101) C12M 23/34 (20130101) C12M 23/38 (20130101) C12M 25/02 (20130101) C12M 27/02 (20130101) C12M 29/04 (20130101) C12M 29/06 (20130101) C12M 35/04 (20130101) C12M 35/08 (20130101) C12M 41/12 (20130101) C12M 41/26 (20130101) C12M 41/40 (20130101) C12M 41/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/20 (20130101) C12N 5/068 (20130101) C12N 5/0679 (20130101) C12N 5/0696 (20130101) C12N 5/0697 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472619 | Orkin et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Stuart H. Orkin (Brookline, Massachusetts); Daniel E. Bauer (Cambridge, Massachusetts); Jian Xu (Plano, Texas) |
| ABSTRACT | Provided herein are methods and compositions for increasing fetal hemoglobin levels in a cell by disrupting BCL11A expression at the genomic level. Also provided herein are methods and compositions relating to the treatment of hemoglobinopathies by reinduction of fetal hemoglobin levels. |
| FILED | Friday, November 17, 2017 |
| APPL NO | 15/816083 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 38/465 (20130101) Peptides C07K 14/805 (20130101) C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/01 (20130101) Original (OR) Class C12N 15/63 (20130101) C12N 15/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472625 | Tuschl et al. |
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| FUNDED BY |
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| APPLICANT(S) | Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. (Munich, Germany); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. (Munich, Germany); Massachusetts Institute of Technology (Cambridge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Thomas Tuschl (Brooklyn, New York); Phillip D. Zamore (Northborough, Massachusetts); Phillip A. Sharp (Newton, Massachusetts); David P. Bartel (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates to a Drosophila in vitro system which was used to demonstrate that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore, when these 21-23 nt fragments are purified and added back to Drosophila extracts, they mediate RNA interference in the absence of long dsRNA. Thus, these 21-23 nt fragments are the sequence-specific mediators of RNA degradation. A molecular signal, which may be their specific length, must be present in these 21-23 nt fragments to recruit cellular factors involved in RNAi. This present invention encompasses these 21-23 nt fragments and their use for specifically inactivating gene function. The use of these fragments (or chemically synthesized oligonucleotides of the same or similar nature) enables the targeting of specific mRNAs for degradation in mammalian cells, where the use of long dsRNAs to elicit RNAi is usually not practical, presumably because of the deleterious effects of the interferon response. This specific targeting of a particular gene function is useful in functional genomic and therapeutic applications. |
| FILED | Friday, October 16, 2015 |
| APPL NO | 14/885288 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0336 (20130101) A01K 2207/05 (20130101) A01K 2217/075 (20130101) A01K 2227/703 (20130101) A01K 2267/03 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/1079 (20130101) C12N 2310/14 (20130101) C12N 2310/53 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/3521 (20130101) C12N 2330/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472630 | Lorson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Christian Lorson (Columbia, Missouri); Erkan Osman (Columbia, Missouri) |
| ABSTRACT | The invention provides methods and compositions for treatment of spinal muscular atrophy (SMA). In one aspect of the invention, a series of compositions comprising an antisense oligonucleotide targeting the Element 1 site on the SMN2 pre-mRNA and a Morpholino backbone is disclosed. In another aspect of the invention, a method of treating SMA patients by modulating the splicing of SMN2 pre-mRNA to increase the amount of full-length SMN is disclosed. Certain embodiments of the inventive method comprise administering an E1-targeting antisense oligonucleotide, such as Morpholino based antisense oligonucleotide, to a SMA subject. |
| FILED | Friday, December 29, 2017 |
| APPL NO | 15/858421 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/3233 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472674 | Esfandyarpour et al. |
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| FUNDED BY |
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| APPLICANT(S) | GenapSys, Inc. (Redwood City, California) |
| ASSIGNEE(S) | GENAPSYS, INC. (Redwood City, California) |
| INVENTOR(S) | Hesaam Esfandyarpour (Redwood City, California); Mark Oldham (Emerald Hills, California) |
| ABSTRACT | A method comprises magnetically holding a bead carrying biological material (e.g., nucleic acid, which may be in the form of DNA fragments or amplified DNA) in a specific location of a substrate, and applying an electric field local to the bead to isolate the biological material or products or byproducts of reactions of the biological material. For example, the bead is isolated from other beads having associated biological material. The electric field in various embodiments concentrates reagents for an amplification or sequencing reaction, and/or concentrates and isolates detectable reaction by-products. For example, by isolating nucleic acids around individual beads, the electric field can allow for clonal amplification, as an alternative to emulsion PCR. In other embodiments, the electric field isolates a nanosensor proximate to the bead, to facilitate detection of at least one of local pH change, local conductivity change, local charge concentration change and local heat. The beads may be trapped in the form of an array of localized magnetic field regions. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/360369 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 3/502761 (20130101) B01L 7/52 (20130101) B01L 2200/10 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2200/0689 (20130101) B01L 2300/12 (20130101) B01L 2300/089 (20130101) B01L 2300/123 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0887 (20130101) B01L 2400/043 (20130101) B01L 2400/0415 (20130101) B01L 2400/0418 (20130101) B01L 2400/0421 (20130101) B01L 2400/0424 (20130101) B01L 2400/0427 (20130101) B01L 2400/0478 (20130101) B01L 2400/0655 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/30 (20130101) B03C 1/286 (20130101) B03C 1/288 (20130101) B03C 5/005 (20130101) B03C 5/022 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 2523/307 (20130101) C12Q 2523/307 (20130101) C12Q 2523/307 (20130101) C12Q 2563/116 (20130101) C12Q 2563/116 (20130101) C12Q 2563/143 (20130101) C12Q 2563/143 (20130101) C12Q 2565/543 (20130101) C12Q 2565/543 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 60/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/40 (20130101) G01N 27/4145 (20130101) G01N 27/4146 (20130101) G01N 33/5438 (20130101) G01N 2001/4038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472677 | Jamieson, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Translational Therapeutics, Inc. (Arlington, Massachusetts) |
| ASSIGNEE(S) | Translational Therapeutics, Inc. (Arlington, Massachusetts) |
| INVENTOR(S) | Gordon A. Jamieson, Jr. (Arlington, Massachusetts); Katherine L. B. Borden (St. Laurent, Canada); Biljana Culjkovic (Montreal, Canada); Alex Kentsis (New York, New York) |
| ABSTRACT | Provided are methods and compositions for inhibiting eukaryotic translation initiation factor eIF4E. Such methods and compositions may be used alone or in conjunction with other therapies, such as gene therapies, for inhibiting cell proliferation and/or treating cancer. |
| FILED | Wednesday, July 10, 2013 |
| APPL NO | 13/938510 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4196 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472679 | Suthanthiran et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithica, New York) |
| INVENTOR(S) | Manikkam Suthanthiran (Scarsdale, New York); Joseph E. Schwartz (East Setauket, New York); Ruchuang Ding (Beechurst, New York); Thangamani Muthukumar (New York, New York) |
| ABSTRACT | Measurement of mRNAs in urinary cells offers a noninvasive means of diagnosing fibrosis in kidneys. One aspect of the invention is a method that includes: (a) measuring quantities of vimentin mRNA, NKCC2 mRNA, and E-cadherin mRNA in a test sample of cells obtained from urine; and (b) determining whether the vimentin mRNA quantity is higher, the NKCC2 mRNA quantity is lower, or the E-cadherin mRNA is higher than in healthy urinary cells; and thereby detecting that the sample is a fibrotic kidney sample. Step (a) can also include measuring the quantity of RNA expressed by a housekeeping gene (e.g., 18S rRNA). The quantities of vimentin mRNA, NKCC2 mRNA, and E-cadherin mRNA can be normalized against the quantity of housekeeping gene RNA. |
| FILED | Wednesday, May 15, 2013 |
| APPL NO | 14/400873 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472688 | Lau et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Warren Lau (Stanford, California); Elizabeth Sattely (Stanford, California) |
| ABSTRACT | The present invention provides compositions and methods for biosynthetically producing podophyllotoxin intermediates and derivatives including enzymes and their equivalents involved in the biosynthetic production of podophyllotoxin intermediates and derivatives. |
| FILED | Saturday, August 20, 2016 |
| APPL NO | 15/242525 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) C12N 9/0008 (20130101) C12N 9/0071 (20130101) C12N 9/0073 (20130101) C12N 9/1007 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/181 (20130101) Enzymes C12Y 102/01 (20130101) C12Y 103/05001 (20130101) C12Y 114/11 (20130101) C12Y 114/13 (20130101) C12Y 114/21 (20130101) Original (OR) Class C12Y 201/01 (20130101) C12Y 201/01042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473628 | Goldhor et al. |
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| FUNDED BY |
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| APPLICANT(S) | Speech Technology and Applied Research Corporation (Bedford, Massachusetts); Richard S. Goldhor (Belmont, Massachusetts) |
| ASSIGNEE(S) | Speech Technology and Applied Research Corporation (Bedford, Massachusetts) |
| INVENTOR(S) | Richard Goldhor (Belmont, Massachusetts); Keith Gilbert (Framingham, Massachusetts); Joel MacAuslan (Nashua, New Hampshire); Karen Payton (Natick, Massachusetts) |
| ABSTRACT | In environments (such as acoustic and bioelectrical environments) characterized by multiple simultaneous sources, effective blind source separation from sensor response mixtures becomes difficult as the number of sources increases—especially when the true number of sources is both unknown and changing over time. However, in some environments, non-sensor information can provide useful hypotheses for some sources. Embodiments of the present invention provide an adaptive filtering architecture for validating such source hypotheses, extracting an estimated representation of source signals corresponding to valid hypotheses, and improving the separation of the remaining “hidden” source signals from the sensor response mixtures. |
| FILED | Monday, July 01, 2013 |
| APPL NO | 13/933060 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 3/12 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/14 (20130101) G01N 29/4472 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473644 | Di Carlo et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dino Di Carlo (Los Angeles, California); Peter Tseng (Saratoga, California); Ivan Pushkarsky (San Diego, California) |
| ABSTRACT | A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns. |
| FILED | Monday, August 20, 2018 |
| APPL NO | 16/105627 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 2300/168 (20130101) B01L 2300/0654 (20130101) B01L 2300/0829 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/247 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) G01N 33/487 (20130101) G01N 33/582 (20130101) G01N 33/5026 (20130101) Original (OR) Class G01N 2021/6419 (20130101) G01N 2021/6441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473661 | Geskin et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Larisa J. Geskin (Riverdale, New York); Brittany Lynn O'Neil Dulmage (Pittsburgh, Pennsylvania); Louis D. Falo, Jr. (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention relates to biomarkers associated with CTCL, including TOX, PLS3, KIR3DL2, GATA3 and RUNX3, where increased expression, relative to normal control, of one or more of TOX, PLS3, KIR3DL2, and/or GATA3 is associated with CTCL and decreased expression of RUNX3, relative to normal control, is associated with CTCL. One or more of these biomarkers may be used to diagnose CTCL and/or design and monitor treatment. |
| FILED | Thursday, August 06, 2015 |
| APPL NO | 14/819950 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) A61K 31/395 (20130101) A61K 31/519 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) A61N 5/062 (20130101) A61N 2005/0661 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 33/57426 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473662 | Torti et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | WAKE FOREST UNIVERSITY HEALTH SCIENCES (Winston Salem, North Carolina) |
| INVENTOR(S) | Frank M. Torti (Avon, Connecticut); Suzy V. Torti (Avon, Connecticut); Lance Miller (Winston-Salem, Connecticut) |
| ABSTRACT | Compositions and methods useful for diagnosis and prognosis of cancer are provided. More particularly, methods for detecting breast or prostate cancer protein or nucleic acid biomarkers consisting of iron homeostasis biomarkers in a biological sample obtained from a subject are provided. |
| FILED | Wednesday, September 21, 2016 |
| APPL NO | 15/272396 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57415 (20130101) G01N 33/57434 (20130101) G01N 33/57449 (20130101) G01N 33/57484 (20130101) Original (OR) Class G01N 2333/575 (20130101) G01N 2333/705 (20130101) G01N 2800/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473668 | Van Dam et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); SOFIE BIOSCIENCES, INC. (Culver City, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); SOFIE BIOSCIENCES, INC. (Culver City, California) |
| INVENTOR(S) | R. Michael Van Dam (Los Angeles, California); Melissa Moore (Culver City, California); Brandon Maraglia (Culver City, California); Daniel Thompson (Culver City, California) |
| ABSTRACT | A self-shielded, bench-top radiochemistry system, including a radioactive isotope dispensing module configured to draw an isotope out of a vial and dispense one or more metered doses of the isotope to a concentration module that concentrates the metered dose into a droplet amount of isotope and a synthesizer module that delivers the droplet amount of isotope along with one or more reagents to an electrowetting on dielectrics (EWOD) chip to produce a radiolabeled molecule. |
| FILED | Friday, June 05, 2015 |
| APPL NO | 15/315369 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) A61B 6/48 (20130101) A61B 6/542 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) Original (OR) Class Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/015 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/0005 (20130101) Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473670 | Evers et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky); University of Massachusetts (Worcester, Massachusetts); Lund University (Malmö, Sweden) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky); University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | B. Mark Evers (Lexington, Kentucky); Jing Li (Lexington, Kentucky); Paul Dobner (Worcester, Massachusetts); Olle Melander (Malmö, Sweden) |
| ABSTRACT | The presently disclosed subject matter relates to a method for predicting increased risk of obesity on a non-obese subject. More particularly, the presently disclosed subject matter relates to a method of predicting increased risk of obesity in a non-obese subject by determining a level of neurotensin expression in a biological sample from the subject and comparing the level of neurotensin expression in the sample with a control level. The presently disclosed subject matter further relates to a method of preventing and/or treating obesity in a subject in need thereof by administering to the subject an effective amount of an agent that inhibits neurotensin. |
| FILED | Monday, February 27, 2017 |
| APPL NO | 15/443266 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2333/912 (20130101) G01N 2440/14 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473675 | Kalantar-Zadeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Quest Diagnostics Investments Incorporated (Wilmington, Delaware); Los Angeles Biomedical Research Institute (Torrance, California) |
| ASSIGNEE(S) | Quest Diagnostics Investments Incorporated (Wilmington, Delaware); Los Angeles Biomedical Research Institute (Torrance, California) |
| INVENTOR(S) | Kamyar Kalantar-Zadeh (Torrance, California); Michael P. Caulfield (Oceanside, California); Wael A. Salameh (San Juan Capistrano, California) |
| ABSTRACT | Described herein are methods for determining the overall survival of maintenance hemodialysis patients. The methods include measuring low density lipoprotein (LDL) particle size and subfraction concentrations as prognostic tools for early mortality risk detection. For example, the presence of increased very small LDL concentration or decreased LDL particle size in blood-serum serves as a useful means for prognostic risk assessment and monitoring. |
| FILED | Friday, April 07, 2017 |
| APPL NO | 15/481664 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473916 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Lihong Wang (St. Louis, Missouri); Jinyang Liang (St. Louis, Missouri); Liren Zhu (St. Louis, Missouri); Cheng Ma (St. Louis, Missouri) |
| ABSTRACT | A system and method for compressed-sensing ultrafast photography for two-dimensional dynamic imaging is disclosed. The system and method may capture non-repetitive time-evolving events at up to about 100 billion frames per second. In an aspect, a digital micromirror device (DMD) may be added as the spatial encoding module. By using the DMD and applying the CUP reconstruction algorithm, a conventional 1D streak camera may be transformed to a 2D ultrafast imaging device. The resultant system may capture a single, non-repetitive event at up to 100 billion frames per second with appreciable sequence depths (up to about 350 frames per acquisition). In another aspect, a dichroic mirror may be used to separate signals into two color channels, and may further expand CUP's functionality into the realm of four-dimensional x, y, λ, t ultrafast imaging, maximizing the information content that may be simultaneously acquired from a single instrument. On the basis of compressed sensing (CS), CUP may encode the spatial domain with a pseudo-random binary pattern, followed by a shearing operation in the temporal domain, performed using a streak camera with a fully opened entrance slit. This encoded, sheared three-dimensional (3D) x, y, t scene may then be measured by a 2D detector array, such as a CCD, within a single snapshot. The image reconstruction process follows a strategy similar to CS-based image restoration—iteratively estimating a solution that minimizes an objective function. However, unlike CS-based image restoration algorithms, which target the reconstruction of a 2D x, y image, CUP reconstruction recovers a 3D x, y, t movie by applying regularization over both the spatial domain and the temporal domain. |
| FILED | Thursday, February 23, 2017 |
| APPL NO | 15/441207 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 26/0833 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 13/218 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474029 | Mirkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Fengwei Huo (Evanston, Illinois); Zijian Zheng (Kowloon, China PRC); Gengfeng Zheng (Ambler, Pennsylvania) |
| ABSTRACT | The disclosure relates to methods of printing indicia on a substrate using a tip array comprised of elastomeric, compressible polymers. The tip array can be prepared using conventional photolithographic methods and can be tailored to have any desired number and/or arrangement of tips. Numerous copies (e.g., greater than 15,000, or greater than 11 million) of a pattern can be made in a parallel fashion in as little as 40 minutes. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/257143 |
| ART UNIT | 2854 — Printing/Measuring and Testing |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/856 (20130101) Y10S 977/874 (20130101) Y10S 977/878 (20130101) Y10S 977/887 (20130101) Y10S 977/888 (20130101) Y10S 977/902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10475352 | Cramer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Steven C. Cramer (Irvine, California); Jessica M. Cassidy (Huntington Beach, California); Vu Le (Irvine, California); Alison L. McKenzie (Capistrano Beach, California); Walt Scacchi (Corona Del Mar, California); Robert Zhou (Monterey Park, California); Jutta Heckhausen (Irvine, California); William F. Genevro (Oakland, California); Lucy Dodakian (Oakland, California); Jill See (Oakland, California) |
| ABSTRACT | A rehabilitation system includes a portable patient workstation configured to facilitate in-home rehabilitation therapy. In some embodiments, the workstation includes a computer configured to host computer-based activities that provide rehabilitative exercise to a patient when the patient participates in the activities, a monitor electrically connected to the computer and configured to display screens of the computer-based activities, a table upon which the monitor can be supported, a tabletop console supported on the table, the console including multiple integral user interface devices that are connected to the computer and adapted to receive patient inputs while the patient is participating in the activities, and a network interface device with which data can be transmitted and received by the patient workstation via a network. |
| FILED | Thursday, September 01, 2016 |
| APPL NO | 15/254029 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/11 (20130101) A61B 5/1118 (20130101) A61B 2505/09 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/4035 (20151001) A63B 23/14 (20130101) A63B 23/16 (20130101) A63B 23/1209 (20130101) A63B 71/0622 (20130101) A63B 2022/0094 (20130101) A63B 2071/063 (20130101) A63B 2071/0625 (20130101) A63B 2071/0638 (20130101) A63B 2071/0658 (20130101) A63B 2207/02 (20130101) A63B 2220/51 (20130101) A63B 2220/803 (20130101) A63B 2220/807 (20130101) Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 13/24 (20140902) A63F 13/213 (20140902) A63F 13/218 (20140902) A63F 13/428 (20140902) Coin-freed or Like Apparatus G07F 17/32 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/06 (20130101) G09B 19/003 (20130101) Original (OR) Class G09B 19/0038 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/30 (20180101) G16H 40/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10475533 | Hanina et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AIC Innovations Group, Inc. (New York, New York) |
| ASSIGNEE(S) | AIC Innovations Group, Inc. (New York, New York) |
| INVENTOR(S) | Adam Hanina (New York, New York); Gordon Kessler (Mt. Kisco, New York); Lei Guan (Harrison, New Jersey) |
| ABSTRACT | A medication management system is described that is operable to determine whether a user is actually following a protocol, provide additional assistance to a user, starting with instructions, video instructions, and the like, and moving up to contact from a medication administrator if it is determined that the user would need such assistance in any medical adherence situation, including clinical trial settings, home care settings, healthcare administration locations, such as nursing homes, clinics, hospitals and the like. Suspicious activity on the part of a patient or other user of the system is identified and can be noted to a healthcare provider or other service provider where appropriate. |
| FILED | Monday, May 21, 2018 |
| APPL NO | 15/985285 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/1128 (20130101) A61B 5/4833 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) G06F 19/3456 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00 (20130101) G06K 9/00771 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/22 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/10 (20180101) Original (OR) Class G16H 20/13 (20180101) Pictorial Communication, e.g Television H04N 7/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476825 | Hsu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California) |
| ASSIGNEE(S) | Salk Institue for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Patrick D. Hsu (San Diego, California); Silvana Konermann (San Diego, California) |
| ABSTRACT | Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA. |
| FILED | Tuesday, March 27, 2018 |
| APPL NO | 15/937699 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/85 (20130101) C12N 15/102 (20130101) C12N 15/113 (20130101) C12N 15/8201 (20130101) C12N 15/8213 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) C12N 2310/3519 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/08 (20130101) H04L 9/30 (20130101) H04L 45/745 (20130101) H04L 51/08 (20130101) H04L 51/12 (20130101) Original (OR) Class H04L 51/14 (20130101) H04L 51/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10470828 | Markvicka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Eric Markvicka (Ravenna, Nebraska); Tom Frederick (Omaha, Nebraska); Jack Mondry (Stillwater, Minnesota); Joe Bartels (Lincoln, Nebraska); Shane Farritor (Lincoln, Nebraska) |
| ABSTRACT | The various robotic medical devices include robotic devices that are disposed within a body cavity and positioned using a support component disposed through an orifice or opening in the body cavity. Additional embodiments relate to devices having arms coupled to a device body wherein the device has a minimal profile such that the device can be easily inserted through smaller incisions in comparison to other devices without such a small profile. Further embodiments relate to methods of operating the above devices. |
| FILED | Thursday, March 12, 2015 |
| APPL NO | 14/656109 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Original (OR) Class A61B 90/361 (20160201) A61B 2017/2906 (20130101) A61B 2018/00595 (20130101) A61B 2018/00982 (20130101) A61B 2034/302 (20160201) Technical Subjects Covered by Former US Classification Y10T 74/20317 (20150115) Y10T 74/20329 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471099 | Lodish et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Harvey Lodish (Brookline, Massachusetts); Hidde L. Ploegh (Brookline, Massachusetts); Hsiang-Ying Lee (Cambridge, Massachusetts); Jiahai Shi (Kowloon, China Hong Kong); Lenka Hoffman (Malden, Massachusetts); Novalia Pishesha (Cambridge, Massachusetts) |
| ABSTRACT | Methods for the in vitro production of enucleated red blood cells and the enucleated red blood cells thus prepared are provided. Such enucleated red blood cells may express a sortaggable surface protein, which allows for surface modification in the presence of a sortase. Also described herein are surface modified enucleated red blood cells, e.g., conjugated with an agent of interest such as a peptide, a detectable label, or a chemotherapeutic agent, and uses thereof in delivering the agent to a subject. |
| FILED | Friday, May 09, 2014 |
| APPL NO | 14/890241 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/072 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/18 (20130101) Original (OR) Class Peptides C07K 14/47 (20130101) C07K 14/705 (20130101) C07K 14/70582 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0641 (20130101) C12N 2501/14 (20130101) C12N 2501/26 (20130101) C12N 2501/125 (20130101) C12N 2501/999 (20130101) C12N 2501/2303 (20130101) C12N 2501/2306 (20130101) C12N 2506/11 (20130101) C12N 2510/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471273 | Segev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Eran Segev (Pasadena, California); Laurent Moreaux (Pasadena, California); Trevor M. Fowler (Pasadena, California); Andrei Faraon (La Canada Flintridge, California); Michael L. Roukes (Pasadena, California) |
| ABSTRACT | A neural probe for light stimulation of a tissue is provided. The probe includes a base that has light supplying circuitry, and one or more elongated microsized shanks extending from the base. Each shank has a longitudinal axis and includes one or more waveguides extending along the shank's length, with the waveguides being optically connected to the light supplying circuitry. In addition, each of the waveguides is optically connected to a diffraction grating coupler that emits a light beam from the shank when light passes from the base through the waveguide and to the diffraction grating coupler. The emitted light beam has a propagation direction at a set angle relative to an axis that is substantially normal to the longitudinal axis of the shank. A method for stimulating a tissue using the neural probe is also provided. |
| FILED | Monday, October 17, 2016 |
| APPL NO | 15/295991 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0601 (20130101) Original (OR) Class A61N 5/0622 (20130101) A61N 2005/063 (20130101) A61N 2005/0612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471276 | Beckner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | William Beckner (North Potomac, Maryland); John A. Ives (Alexandria, Virginia); Mark Bachman (Irvine, California); Guann-Pyng Li (Irvine, California) |
| ABSTRACT | An apparatus and method utilizes photonics, particularly lasers, and biometric feedback for physiological and neurological stimulation. While many areas of the body are candidates, such laser stimulation is particularly directed to the outer ear. Lasers positioned over the ear stimulate targets on the outer ear for pain and stress management and regulation of the autonomic nervous system to affect symptoms and clinical conditions. Laser positioning, wavelength, aiming, focus, power, power density, timing, and sequencing are managed and modified dynamically in real time to effect a personalized and effective treatment protocol. |
| FILED | Friday, October 07, 2016 |
| APPL NO | 15/766802 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/021 (20130101) A61B 5/0532 (20130101) A61B 5/0816 (20130101) A61B 5/02416 (20130101) A61B 5/4836 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0619 (20130101) Original (OR) Class A61N 5/0622 (20130101) A61N 2005/067 (20130101) A61N 2005/0605 (20130101) A61N 2005/0647 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471279 | Hollebeek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Robert Hollebeek (Berwyn, Pennsylvania); Derek Dolney (Huntingdon Valley, Pennsylvania) |
| ABSTRACT | Particle therapy systems and methods for particle dose imaging are provided. A particle therapy system includes a particle beam source for generating a particle beam; and at least one particle detector including an ionization chamber having a mesh electrode. The at least one particle detector is configured to receive the particle beam and to generate an ionization current responsive to the received particle beam. The ionization current may be used to characterize the particle beam. |
| FILED | Wednesday, August 06, 2014 |
| APPL NO | 14/453292 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1071 (20130101) Original (OR) Class A61N 2005/1087 (20130101) Measurement of Nuclear or X-radiation G01T 1/2935 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471503 | Wright et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | QuesTek Innovations LLC (Evanston, Illinois) |
| ASSIGNEE(S) | Questek Innovations LLC (Evanston, Illinois) |
| INVENTOR(S) | James A. Wright (Los Gatos, California); Jason Sebastian (Chicago, Illinois); Herng-Jen Jou (Wilmette, Illinois) |
| ABSTRACT | Provided herein are titanium alloys that can achieve a combination of high strength and high toughness or elongation, and a method to produce the alloys. By tolerating iron, oxygen, and other incidental elements and impurities, the alloys enable the use of lower quality scrap as raw materials. The alloys are castable and can form α-phase laths in a basketweave morphology by a commercially feasible heat treatment that does not require hot-working or rapid cooling rates. The alloys comprise, by weight, about 3.0% to about 6.0% aluminum, 0% to about 1.5% tin, about 2.0% to about 4.0% vanadium, about 0.5% to about 4.5% molybdenum, about 1.0% to about 2.5% chromium, about 0.20% to about 0.55% iron, 0% to about 0.35% oxygen, 0% to about 0.007% boron, and 0% to about 0.60% other incidental elements and impurities, the balance of weight percent comprising titanium. |
| FILED | Thursday, February 28, 2013 |
| APPL NO | 13/780831 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 25/00 (20130101) Original (OR) Class Alloys C22C 1/02 (20130101) C22C 14/00 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471648 | Mather et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Patrick Mather (Oxford, Pennsylvania); Xiaofan Luo (Cleveland, Ohio); Andrew M. DiOrio (Windham, New Hampshire); Kyung-Min Lee (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Syracuse University (Syracuse, New York) |
| INVENTOR(S) | Patrick Mather (Oxford, Pennsylvania); Xiaofan Luo (Cleveland, Ohio); Andrew M. DiOrio (Windham, New Hampshire); Kyung-Min Lee (Wright-Patterson AFB, Ohio) |
| ABSTRACT | A functionally graded shape memory polymer (SMP) that has a range of transition temperatures that are spatially distributed in a gradient fashion within one single article. The SMP is formed by post-curing a pre-cured glassy SMP in a linear temperature gradient that imposes different vitrification temperature limits at different positions along the gradient. Utilizing indentation-based surface shape memory coupled with optical measurements of photoelastic response, the capability of this material to respond over a wide range of thermal triggers is correlated with the graded glass transition behavior. This new class of SMP offers great potential for such applications as passive temperature sensing and precise control of shape evolution during a thermally triggered shape recovery. |
| FILED | Wednesday, March 01, 2017 |
| APPL NO | 15/446487 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 61/06 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/12 (20130101) C08F 220/14 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 2280/00 (20130101) Compositions of Macromolecular Compounds C08L 33/04 (20130101) C08L 63/00 (20130101) C08L 71/02 (20130101) C08L 71/02 (20130101) C08L 75/04 (20130101) C08L 2205/05 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24479 (20150115) Y10T 428/24628 (20150115) Y10T 428/24983 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472089 | Franich |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Goodrich Lighting Systems, Inc. (Oldsmar, Florida) |
| ASSIGNEE(S) | GOODRICH LIGHTING SYSTEMS, INC. (Oldsmar, Florida) |
| INVENTOR(S) | David Franich (Tempe, Arizona) |
| ABSTRACT | A dual mode light includes a housing, at least one first light emitter disposed in the housing, a plurality of second light emitters each disposed in the housing an emitter distance from the at least one first light emitter, a first shield disposed in the housing a first shield distance from the at least one first light emitter, wherein the first shield distance is less than the emitter distance, and a second shield disposed in the housing a second shield distance around the plurality of second light emitters. |
| FILED | Tuesday, March 01, 2016 |
| APPL NO | 15/057706 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 47/06 (20130101) Original (OR) Class Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 11/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472245 | Qadri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Syed B. Qadri (Fairfax Station, Virginia); Bhakta B. Rath (Oakton, Virginia); Edward P. Gorzkowski, III (Odenton, Maryland) |
| ABSTRACT | A method of making Nanostructured Zinc Silicate from renewable sources comprising preparing powders of husks, preparing powders of ZnO, mixing the powders of husks and the powders of ZnO and forming a homogenous sample powder, pressing the homogenous sample and forming pellets, heating the pellets and forming nanostructured zinc silicate. The nanostructured zinc silicate from renewable sources product of the process of preparing powders of husks, preparing powders of ZnO, mixing the powders of husks and the powders of ZnO and forming a homogenous sample powder, pressing the homogenous sample and forming pellets, heating the pellets and forming nanostructured zinc silicate. |
| FILED | Tuesday, October 17, 2017 |
| APPL NO | 15/786245 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/20 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472299 | Matzger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Adam J. Matzger (Ann Arbor, Michigan); Kyle McDonald (Kissimmee, Florida) |
| ABSTRACT | Employing non-energetic MCPs as hosts (fuel) for the adsorption of oxidant molecules enables the intimate and molecular scale mixing of fuel and oxidizer on a level that is not commonly achievable in traditional energetic mixtures. The adsorption of the oxidants into MOF-5 resulted in increased heat released upon decomposition, which shows potential for utilization of this method as a platform to develop high-performance primary energetic materials. |
| FILED | Friday, June 23, 2017 |
| APPL NO | 15/631519 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0083 (20130101) C06B 25/00 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472398 | Klapoetke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of The University of Alberta (Edmonton, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of The University of Alberta (Edmonton, Alberta, Canada) |
| INVENTOR(S) | Nathan Klapoetke (Cambridge, Massachusetts); Brian Yichiun Chow (Cambridge, Massachusetts); Edward Boyden (Chestnut Hill, Massachusetts); Gane Ka-Shu Wong (Edmontn, Canada); Yongku Peter Cho (Cambridge, Massachusetts) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. |
| FILED | Monday, November 12, 2012 |
| APPL NO | 14/357635 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0661 (20130101) A61N 2005/0662 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) G01N 33/48728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472399 | Klapoetke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Alberta, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of The University of Alberta (Edmonton, Alberta, AB, Canada) |
| INVENTOR(S) | Nathan Klapoetke (Ashburn, Virginia); Brian Yichiun Chow (Cherry Hill, New Jersey); Edward Boyden (Chestnut Hill, Massachusetts); Gane Ka-Shu Wong (Edmonton, Canada); Yongku Peter Cho (Vernon, Connecticut) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/359875 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0661 (20130101) A61N 2005/0662 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) G01N 33/48728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472450 | Lundin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey G. Lundin (Springfield, Virginia); Christopher L. McGann (Glenmont, New York); Benjamin C. Streifel (Puyallup, Washington); Michael G. Stockelman (Silver Spring, Maryland); Chaselynn M. Watters (Silver Spring, Maryland); Christopher J. Santee (Lansdowne, Virginia); Timothy B. Bentley (Rockville, Maryland); James H. Wynne (Alexandria, Virginia) |
| ABSTRACT | A compound made by copolymerizing a poly(N-isopropylacrylamide) chain transfer agent, an acrylate salt, and a polyethylene glycol diacrylate. A compound made by copolymerizing a polyethylene glycol, a glycerol ethoxylate, and an aliphatic diisocyanate. |
| FILED | Thursday, March 09, 2017 |
| APPL NO | 15/454267 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/24 (20130101) A61L 15/26 (20130101) A61L 15/425 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 293/005 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/14 (20130101) C08G 18/73 (20130101) C08G 18/6677 (20130101) C08G 2101/0083 (20130101) C08G 2210/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/00 (20130101) C08J 2205/022 (20130101) C08J 2205/044 (20130101) C08J 2207/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472620 | Nelson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | John Richard Nelson (Clifton Park, New York); David Roger Moore (Rexford, New York); Robert Scott Duthie (Schenectady, New York); Matthew Jeremiah Misner (Delanson, New York); Gregory Andrew Grossmann (Halfmoon, New York); Elizabeth Marie Dees (Ballston Lake, New York); Patrick McCoy Spooner (Slingerlands, New York); Erik Leeming Kvam (Niskayuna, New York); Andrew Arthur Paul Burns (Niskayuna, New York); Vicki Herzl Watkins (Alplaus, New York) |
| ABSTRACT | A method is provided herein, the method includes: applying a sample comprising target nucleic acids to a sample application zone of a substrate; and flowing a nucleic acid amplification reaction mixture across a length of the substrate through the sample application zone to amplify the target nucleic acid forming a nucleic acid amplification product; wherein the target nucleic acid having a first molecular weight is substantially immobilized at the sample application zone and wherein the amplification product having a second molecular weight migrates away from the sample application zone. An associated device is also provided. |
| FILED | Tuesday, July 01, 2014 |
| APPL NO | 14/321160 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472787 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | August N Johnson (Raymond, Mississippi); Michael I Hammons (Clinton, Mississippi); Gary E Johnston (Rayville, Louisiana); James C Ray (Clinton, Mississippi) |
| ABSTRACT | In certain embodiments, a cap repair assembly includes first and second pile brackets for rigid mounting onto first and second piles of a pier; a cap beam for rigid mounting onto super-structure of the pier; first and second cap beam plates for rigid mounting onto the cap beam at different ends of the cap beam; first and second compression arms rotatably connected (i) at first ends to the first and second pile brackets and (ii) at second ends to the first and second cap beam plates. The cap repair assembly restores the load capacity of damaged or degraded piers. The cap repair assembly can further include one or more steel banding straps. |
| FILED | Friday, May 18, 2018 |
| APPL NO | 15/984190 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Construction of Bridges, or Viaducts; Assembly of Bridges E01D 22/00 (20130101) Hydraulic Engineering E02B 3/06 (20130101) E02B 17/0034 (20130101) Original (OR) Class Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 37/00 (20130101) Scaffolding; Forms; Shuttering; Building Implements or Aids, or Their Use; Handling Building Materials on the Site; Repairing, Breaking-up or Other Work on Existing Buildings E04G 23/0218 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473028 | DiTomasso et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | John C. DiTomasso (Glastonbury, Connecticut); Enzo DiBenedetto (Berlin, Connecticut) |
| ABSTRACT | A clutched compressor section of a gas turbine engine coupled to a rotor shaft. The clutched compressor section includes at least one decoupleable rotor stage, the decoupleable rotor stage switchable between a coupled condition and a decoupled condition with a clutch mechanism, the coupled condition coupling the decoupleable rotor stage with the rotor shaft, the decoupled condition decoupling the decoupleable rotor stage from the rotor shaft. |
| FILED | Monday, July 17, 2017 |
| APPL NO | 15/651497 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/066 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/113 (20130101) Original (OR) Class F02C 7/36 (20130101) F02C 9/00 (20130101) Non-positive-displacement Pumps F04D 19/026 (20130101) F04D 25/02 (20130101) F04D 29/053 (20130101) F04D 29/266 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2220/3219 (20130101) F05D 2240/20 (20130101) F05D 2260/404 (20130101) F05D 2260/4023 (20130101) F05D 2270/112 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 27/10 (20130101) F16D 35/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473094 | Phoenix |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Austin Phoenix (Washington, District of Columbia) |
| ABSTRACT | A thermally-controlled actuator includes a cylindrical anisogrid structure formed from a plurality of circumferentially offset clockwise and counter-clockwise helical members, and a plurality of longitudinally offset cylindrical ring members. A thermal control element is configured to control the temperature of at least some of the members. The cylindrical anisogrid structure has a top interface constraint and a bottom interface constraint, and the thermal control element is configured to control a displacement of the top interface constraint relative to the bottom interface constraint via control of the temperature of at least one of the helical members. |
| FILED | Monday, February 12, 2018 |
| APPL NO | 15/894679 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/065 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 26/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473225 | DeFelice et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Robert DeFelice (South Windsor, Connecticut); Scott W. Simpson (Easthampton, Massachusetts) |
| ABSTRACT | A passive in-line valve configured to be actuated without an external control includes a valve housing defining an inlet, an outlet, and a flow path between the inlet and the outlet and a piston housing extending inwardly from the housing. The valve includes a valve piston movably disposed within the piston housing, the valve piston including an upstream side and a downstream side. The valve also includes a control mechanism disposed at least partially within the housing and configured to port outlet static pressure to the upstream cavity in a first state such that pressure is equalized on the valve piston. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 15/939855 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 17/10 (20130101) Original (OR) Class F16K 17/044 (20130101) F16K 31/1221 (20130101) F16K 31/1223 (20130101) F16K 31/1225 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 7/014 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/3367 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473332 | Hannwacker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | David Andrew Hannwacker (Torrance, California); Stephen John Howell (West Newbury, Massachusetts); John Carl Jacobson (Melrose, Massachusetts); Joseph Douglas Monty (Boxford, Massachusetts) |
| ABSTRACT | A combustor assembly for a gas turbine engine includes an inner liner, an outer liner, and a combustor dome. The inner liner, outer liner, and combustor dome together define at least in part a combustion chamber having an annulus height. Additionally, the combustor assembly includes a fuel-air injector hardware assembly positioned at least partially within an opening of the combustor dome. The fuel-air injector hardware assembly includes a heat shield located at least partially within the combustion chamber, the heat shield defining an outer diameter. A ratio of the annulus height of the combustion chamber to the outer diameter of the heat shield may be at least about 1.5:1. |
| FILED | Thursday, February 25, 2016 |
| APPL NO | 15/053582 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/007 (20130101) Original (OR) Class F23R 3/14 (20130101) F23R 3/283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473429 | Louchard |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems lnformation and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Eric M. Louchard (Miami, Florida) |
| ABSTRACT | A projectile detection technique is disclosed. The technique helps improve the self-defense capabilities of strategic platforms such as naval ships against asymmetric threats such as anti-ship missiles (ASMs). These threats can be particularly challenging in a highly cluttered maritime environment, where the threats can be too close for radar to accurately detect. In one example, the projectile detection technique automatically detects ASMs flying above the horizon by using mid-wavelength infrared (MWIR) and visible/near-infrared (VNIR) camera systems, and locating the horizon line and segmenting the imagery into different regions. Projectiles are detected in the near-horizon segment using a Fourier phase-only transform and convolution matched filters to enhance exceedances, then applying multi-frame processing to measure persistence and scintillation (e.g., flicker from missile exhaust) to help filter out background clutter objects. The use of the phase-only transform, matched filters, and multi-frame processing helps detect single-point anomalies and distinguish ASMs from background clutter. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/106513 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Weapon Sights; Aiming F41G 3/00 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473452 | Perea et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America, as represented by the Secretary of the Army (Fort Belvoir, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Pentagon Washington, District of Columbia) |
| INVENTOR(S) | James D. Perea (Alexandria, Virginia); Bradley W. Libbey (Alexandria, Virginia) |
| ABSTRACT | A phase-resolved heterodyne shearing interferometer has been developed for high-rate, whole field observations of transient surface motion. The sensor utilizes polarization multiplexing and multiple carrier frequencies to separate each segment of a shearing Mach-Zehnder interferometer. Post-processing routines have been developed to recombine the segments by extracting the scattered object phase from Doppler shifted intermediate carrier frequencies, providing quantitative relative phase changes and information to create variable shear, phase resolved shearographic fringe patterns without temporal or spatial phase shifting. |
| FILED | Friday, August 24, 2018 |
| APPL NO | 16/111665 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02007 (20130101) G01B 9/02022 (20130101) G01B 9/02032 (20130101) Original (OR) Class G01B 9/02038 (20130101) G01B 9/02084 (20130101) G01B 9/02089 (20130101) G01B 2290/70 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473558 | Adiga et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Umesha P. S. Adiga (Centerville, Ohio); Daylond J. Hooper (Fairborn, Ohio); Nina Joshi (Xenia, Ohio); Daniel S. Banks (Franklin, Ohio); Murali K. Gorantla (Beavercreek, Ohio); Roland Adrian Hogendoorn (Dayton, Ohio); Elizabeth J. Jenkins (Springboro, Ohio); Robert F. Ondera (Casstown, Ohio) |
| ASSIGNEE(S) | UES, INC. (Dayton, Ohio) |
| INVENTOR(S) | Umesha P. S. Adiga (Centerville, Ohio); Daylond J. Hooper (Fairborn, Ohio); Nina Joshi (Xenia, Ohio); Daniel S. Banks (Franklin, Ohio); Murali K. Gorantla (Beavercreek, Ohio); Roland Adrian Hogendoorn (Dayton, Ohio); Elizabeth J. Jenkins (Springboro, Ohio); Robert F. Ondera (Casstown, Ohio) |
| ABSTRACT | An metallographic system comprising a programmable controller, a robotic arm, a specimen clamping or holding device, a sectioning saw, a mounting station, a polishing station, a specimen preparation station, and an analyzer for examining the specimen. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/343903 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/04 (20130101) G01N 1/06 (20130101) Original (OR) Class G01N 1/32 (20130101) G01N 1/36 (20130101) G01N 1/286 (20130101) G01N 23/04 (20130101) G01N 23/203 (20130101) G01N 2001/2873 (20130101) G01N 2223/61 (20130101) Image Data Processing or Generation, in General G06T 7/0004 (20130101) G06T 2207/10061 (20130101) G06T 2207/20016 (20130101) G06T 2207/20064 (20130101) G06T 2207/30156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473587 | Sertel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | Kubilay Sertel (Hilliard, Ohio); Georgios C. Trichopoulos (Tempe, Arizona); Cosan Caglayan (Columbus, Ohio) |
| ABSTRACT | Terahertz (THz) or millimeter wave (mmW) band characterization of a differential-mode device under test (DUT) is performed using a non-contact probing setup based on an integrated circuit that includes the on-chip DUT and an on-chip test fixture as follows. A differential transmission line pair is operatively coupled with the DUT. A first differential antenna pair at a first end of the transmission line pair has a first antenna connected only with the first transmission line and a second antenna connected only with the second transmission line. A second differential antenna pair is likewise connected with a second end of the differential transmission line pair. A THz or mmW transmitter radiates a probe THz or mmW beam to the first differential antenna pair, and an electronic analyzer receives a THz or mmW signal radiated by the second differential antenna pair responsive to the radiation of the probe THz or mmW beam to the first differential antenna pair, thus enabling no-contact S-parameter measurements for characterizing differential-mode, on-wafer, active or passive devices and integrated circuits. |
| FILED | Thursday, May 18, 2017 |
| APPL NO | 15/598844 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3581 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 1/06772 (20130101) G01R 31/303 (20130101) G01R 31/311 (20130101) G01R 31/2822 (20130101) G01R 31/3025 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/003 (20130101) H01P 5/10 (20130101) Antennas, i.e Radio Aerials H01Q 1/36 (20130101) H01Q 15/23 (20130101) H01Q 19/062 (20130101) H01Q 19/132 (20130101) H01Q 25/02 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/085 (20130101) H04L 25/0276 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473692 | Christophersen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Marc Christophersen (Berwyn Heights, Maryland); Bernard F. Phlips (Great Falls, Virginia); Andrew J. Boudreau (Washington, District of Columbia); Michael K. Yetzbacher (Burke, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Marc Christophersen (Berwyn Heights, Maryland); Bernard F. Phlips (Great Falls, Virginia); Andrew J. Boudreau (Washington, District of Columbia); Michael K. Yetzbacher (Burke, Virginia) |
| ABSTRACT | A method of calibrating a topography metrology instrument using a calibration reference, which includes a substrate and a plurality of bi-layer stacks. Each bi-layer stack includes a plurality of bi-layer steps. At least one bi-layer step of the plurality of bi-layer steps includes two materials. The at least one bi-layer step of the plurality of bi-layer steps includes an etch stop layer and a bulk layer. The calibration reference includes a calibration reference step profile includes a plurality of predetermined bi-layer stack heights. The calibration reference step profile and the predetermined bi-layer stack heights are measured using a topography metrology instrument. The topography metrology instrument is calibrated based on the measured calibration reference step profile and the measured bi-layer stack heights. |
| FILED | Tuesday, September 22, 2015 |
| APPL NO | 14/860947 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 40/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473746 | Rossman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Court E. Rossman (Merrimack, New Hampshire); Thomas R. Vaccaro (Hudson, New Hampshire) |
| ABSTRACT | A system and method for rank estimation of electromagnetic emitters is provided. One aspect of the disclosure provides creating a graph of angles of arrival (AoAs) versus range and using a polynomial curve fit against the graph to determine a rank estimation of electromagnetic emitters. Another aspect of the disclosure provides using a search over parameters of the multiple polynomial curve fits, for each hypothesized rank, to optimize the rank estimation results. This search may be a greedy search to improve speed of convergence. Another aspect of the disclosure provides a metric ‘score’ to select the highest probability rank (number of emitters) based on the agreement between the multiple polynomial curve fits and residual AoA errors. |
| FILED | Thursday, July 13, 2017 |
| APPL NO | 15/649117 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/04 (20130101) Original (OR) Class G01S 3/74 (20130101) G01S 3/781 (20130101) G01S 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473861 | Frish |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Harel Frish (Moshav Sede Moshe, Israel) |
| ABSTRACT | A structure for coupling an optical signal between an integrated circuit photonic structure and an external optical fiber is disclosed as in a method of formation. The coupling structure is sloped relative to a horizontal surface of the photonic structure such that light entering or leaving the photonic structure is substantially normal to its upper surface. |
| FILED | Friday, September 21, 2018 |
| APPL NO | 16/138159 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00663 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/04 (20130101) C03C 15/00 (20130101) Optical Elements, Systems, or Apparatus G02B 5/1857 (20130101) G02B 6/13 (20130101) G02B 6/30 (20130101) Original (OR) Class G02B 6/34 (20130101) G02B 6/122 (20130101) G02B 6/124 (20130101) G02B 6/132 (20130101) G02B 6/3628 (20130101) G02B 2006/12061 (20130101) G02B 2006/12092 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473931 | Browne |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SA Photonics, Inc. (Los Gatos, California) |
| ASSIGNEE(S) | SA Photonics, Inc. (Los Gatos, California) |
| INVENTOR(S) | Michael P. Browne (San Mateo, California) |
| ABSTRACT | A wide field of view night vision system is described. The system comprises a head attachment apparatus configured to attach to a user's head and a night vision subsystem. The night vision subsystem comprises one or more night vision image sensors attached to the head attachment apparatus. Each sensor receives input light and produces a digital image of the input light. A processor processes the digital image(s) to produce a wide-field image. The wide-field image spans at least 60 degrees of a user's horizontal field of view. A display and eyepiece attached to the head attachment apparatus receives and displays the wide-field image. The eyepiece is positionable between the display and the user's eye to image the wide-field image into the user's eye. |
| FILED | Tuesday, March 28, 2017 |
| APPL NO | 15/471359 |
| ART UNIT | 2485 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) Original (OR) Class G02B 2027/011 (20130101) G02B 2027/014 (20130101) G02B 2027/0123 (20130101) G02B 2027/0138 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) H04N 5/2258 (20130101) H04N 5/23238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474144 | Wieneke |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Garry Wieneke (Montgomery, Indiana) |
| ABSTRACT | An adaptive situational awareness, decision support, and automated response system operable to receive sensor data or situational awareness data for a region of interest along or in advance of a path of travel of a vehicle obtained from at least a mobile reconnaissance sensor platform and select/execute one or more response programming or plans to operate one or more vehicle equipment items, e.g., a remote interaction, control or jamming system, from a stored database, manual inputs, or a distributive network based on matching of plans/programs with at least one of the sensor outputs or situational awareness data is provided. Apparatus and methods are also provided that enable an exemplary system to obtain data associated with an area surrounding the vehicle and provide this data to other system, subsystems, and personnel. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 15/455802 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0027 (20130101) Original (OR) Class G05D 1/0038 (20130101) G05D 1/0044 (20130101) G05D 1/0214 (20130101) G05D 2201/0209 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474177 | Mezic et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Igor Mezic (Goleta, California); Yoshihiko Susuki (Kyoto, Japan) |
| ABSTRACT | A system and method for stability monitoring, analysis, and control of energy systems, such as electric power systems, is provided. Specifically, the system and method described herein use a Koopman mode analysis to represent the operation of individual components in an energy system and/or to determine and rank a level of stability of the individual components in the energy system. The system and method described herein also use a Koopman mode analysis to determine optimal and/or safe times to release energy stored in storage systems. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 15/940511 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/2513 (20130101) Systems for Regulating Electric or Magnetic Variables G05F 1/66 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/28 (20130101) H02J 13/00 (20130101) H02J 13/001 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/74 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/30 (20130101) Y04S 10/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474375 | Fleming, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kermin Elliott Fleming, Jr. (Hudson, Massachusetts); Simon C. Steely, Jr. (Hudson, New Hampshire); Kent D. Glossop (Nashua, New Hampshire) |
| ABSTRACT | An integrated circuit includes a processor to execute instructions and to interact with memory, and acceleration hardware, to execute a sub-program corresponding to instructions. A set of input queues includes a store address queue to receive, from the acceleration hardware, a first address of the memory, the first address associated with a store operation and a store data queue to receive, from the acceleration hardware, first data to be stored at the first address of the memory. The set of input queues also includes a completion queue to buffer response data for a load operation. A disambiguator circuit, coupled to the set of input queues and the memory, is to, responsive to determining the load operation, which succeeds the store operation, has an address conflict with the first address, copy the first data from the store data queue into the completion queue for the load operation. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/396049 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/065 (20130101) G06F 3/067 (20130101) G06F 3/0619 (20130101) Original (OR) Class G06F 9/3826 (20130101) G06F 9/3834 (20130101) G06F 9/30043 (20130101) G06F 12/00 (20130101) G06F 13/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474690 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Ke Wang (Charlottesville, Virginia); Kevin Skadron (Charlottesville, Virginia); Elaheh Sadredini (Charlottesville, Virginia) |
| ABSTRACT | The present invention introduces the development of a flexible CPU-AP (Computer Processing Unit-Automata Processor) computing infrastructure for mining hierarchical patterns based on Apriori algorithm. A novel automaton design strategy, called linear design, is described to generate automata for matching and counting hierarchical patterns and apply it on SPM (Sequential Pattern Mining). In addition, another novel automaton design strategy, called reduction design, is described for the disjunctive rule matching (DRM) and counting. The present invention shows performance improvement of AP SPM and DRM solutions and broader capability over multicore and GPU (Graphics Processing Unit) implementations of GSP SPM, and shows that AP SPM and DRM solutions outperform state-of-the-art SPM algorithms SPADE and PrefixSpan (especially for larger datasets). |
| FILED | Friday, March 31, 2017 |
| APPL NO | 15/475819 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2465 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474772 | Bolander et al. |
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| FUNDED BY |
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| APPLICANT(S) | Nathan Bolander (Idaho Falls, Idaho); Rajasekhar V. Pulikollu (Nashville, Tennessee); Behrooz Jalalahmadi (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Sentient Science Corporation (Buffalo, New York) |
| INVENTOR(S) | Nathan Bolander (Idaho Falls, Idaho); Rajasekhar V. Pulikollu (Nashville, Tennessee); Behrooz Jalalahmadi (Idaho Falls, Idaho) |
| ABSTRACT | A system and method for determining surface contact fatigue life may use a finite element method to determine when components, such as a power transmission component, may fail in operation. The method may generate a finite element model based on the material parameters related to a power transmission component, generate a surface pressure time history for a loading event based on one or more loading parameters, determine, based on the surface pressure time history for a loading event, a finite element solution that describes stress in the grain structure, calculate damage in the finite element solution using a damage model, and determine whether a damage threshold is exceeded. |
| FILED | Friday, September 14, 2012 |
| APPL NO | 13/617405 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Gearing F16H 2057/0087 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 13/022 (20130101) Electric Digital Data Processing G06F 17/18 (20130101) G06F 17/5018 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474816 | Hall et al. |
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| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | William E. Hall (Clinton, Connecticut); Guerney D. H. Hunt (Yorktown Heights, New York); Ronald N. Kalla (Round Rock, Texas); Jentje Leenstra (Bondorf, Germany); Paul Mackerras (Weston, Australia); William J. Starke (Round Rock, Texas); Jeffrey A. Stuecheli (Austin, Texas) |
| ABSTRACT | A system, a method, and a computer program product for secure memory implementation for secure execution of virtual machines. Data is processed in a first mode and a second mode, and commands are sent to a chip interconnect bus using real addresses, wherein the chip interconnect bus transports a number of bits for the real addresses. A memory controller is operatively coupled to a memory component. A secure memory range is specified by using range registers. If the real address is detected to be in the secure memory range to match a memory component address, a real address bit is set. If the real address is in the memory address hole, a security access violation is detected. If the real address is not in the secure address range and the real address bit is set, the security access violation is detected. |
| FILED | Thursday, December 14, 2017 |
| APPL NO | 15/842279 |
| ART UNIT | 2495 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) G06F 12/1441 (20130101) G06F 13/364 (20130101) G06F 13/404 (20130101) G06F 21/53 (20130101) G06F 21/556 (20130101) Original (OR) Class G06F 21/6281 (20130101) G06F 2009/45587 (20130101) G06F 2212/1052 (20130101) G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474818 | Saxe |
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| FUNDED BY |
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| APPLICANT(S) | Invincea, Inc. (Fairfax, Virginia) |
| ASSIGNEE(S) | Invincea, Inc. (Reston, Virginia) |
| INVENTOR(S) | Joshua Daniel Saxe (Los Angeles, California) |
| ABSTRACT | An apparatus includes a database configured to store a collection of files. The apparatus also includes a counter module configured to calculate a frequency of a data feature in the collection of files. The apparatus also includes a signature generation module operatively coupled to the counter module. The signature generation module is configured to generate a malware signature based on the frequency of the data feature in the collection of files. The malware signature includes an indication of one or more criterion for the data feature, and the malware signature is associated with a malware. The apparatus also includes a communication module configured to receive a target file, and a detection module operatively coupled to the communication module. The detection module is configured to classify the target file as the malware when the target file meets the one or more criterion of the malware signature. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 15/907817 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/13 (20190101) G06F 16/116 (20190101) G06F 21/561 (20130101) G06F 21/565 (20130101) Original (OR) Class G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474952 | Thompson |
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| FUNDED BY |
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| APPLICANT(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Timothy Guy Thompson (Purcellville, Virginia) |
| ABSTRACT | Systems and methods are provided for generating an initial optimized baseline solution to a multi-objective problem. As the baseline solution is implemented, live (e.g., real-time or near real-time) data associated with one or more parameters may be received and compared to expectations of those parameters with the implementation of the initial optimized solution. If a deviation is detected between the expectation of the time progression of the parameters and live data associated with the parameter, then that deviation may be compared to a threshold. If the deviation meets a threshold condition, then an irregular operation may be declared and a new baseline solution may be implemented. The new baseline solution may be obtained as a re-optimized solution. |
| FILED | Tuesday, September 08, 2015 |
| APPL NO | 14/847424 |
| ART UNIT | 2122 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/126 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474953 | Thompson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Timothy Guy Thompson (Purcellville, Virginia); Matthew Phillip Ferringer (Round Hill, Virginia) |
| ABSTRACT | Systems and methods are provided for providing an optimized solution to a multi-objective problem. Potential solutions may be generated from parent solutions to be evaluated according to multiple objectives of the multi-objective problem. If the potential solutions are infeasible, the potential solutions may be perturbed according to a perturbation model to bring the potential solution to feasibility, or at least a reduced level of constraints. The perturbation models may include a weight vector that indicates the amount of perturbation, such as in a forward and/or reverse direction, of decision variables of the potential solutions. In some cases, the perturbation models may be predetermined. In other cases, the perturbation models may be learned, such as based on training constraint data. Additionally, potential solutions may be generated in a secondary optimization where a constraint based optimization may be performed to drive to generating a feasible solution for further evaluation according to objective values. |
| FILED | Monday, September 19, 2016 |
| APPL NO | 15/268840 |
| ART UNIT | 2125 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/126 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10475514 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Xueqing Li (State College, Pennsylvania); Sumitha George (State College, Pennsylvania); John Sampson (State College, Pennsylvania); Sumeet Gupta (State College, Pennsylvania); Suman Datta (South Bend, Indiana); Vijaykrishnan Narayanan (State College, Pennsylvania); Kaisheng Ma (State College, Pennsylvania) |
| ABSTRACT | Embodiments include nonvolatile a memory (NVM) device that can be configured for logic switching and/or digital computing. For example, embodiments of the NVM device can be configured as any one or combination of a memory cell, a D flip flop (DFF), a Backup and Restore circuit (B&R circuit), and/or a latch for a DFF. Any of the NVM devices can have a Fe field effect transistors (FeFET) configured to exploit the IDS-VG hysteresis of the steep switch at low voltage for logic memory synergy. The FeFET-based devices can be configured to include a wide hysteresis, a steep hysteresis edge, and high ratio between the two IDS states at VG=0. |
| FILED | Thursday, May 10, 2018 |
| APPL NO | 15/976315 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/223 (20130101) G11C 11/1675 (20130101) G11C 11/1693 (20130101) G11C 11/2275 (20130101) G11C 11/2293 (20130101) G11C 13/0002 (20130101) G11C 13/0007 (20130101) G11C 13/0061 (20130101) G11C 13/0069 (20130101) G11C 14/009 (20130101) G11C 14/0054 (20130101) G11C 14/0072 (20130101) Original (OR) Class G11C 14/0081 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/78391 (20140902) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476018 | Loo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Yueh-Lin Loo (Princeton, New Jersey); Nicholas C. Davy (Princeton, New Jersey); Melda Sezen Edmonds (Princeton, New Jersey) |
| ABSTRACT | In one aspect, single-junction organic photovoltaic devices are provided exhibiting high Voc values while employing single-junction architecture. A single-junction photovoltaic device described herein comprises an anode, a cathode and an active layer residing between the anode and cathode, the active layer comprising an organic electron donor and an organic electron acceptor, wherein the photovoltaic device generates a Voc of at least 1.4 V. Uniquely, high Voc photovoltaic devices described herein can be transparent to the majority of visible and/or infrared spectral irradiation in some embodiments. |
| FILED | Monday, December 19, 2016 |
| APPL NO | 15/577965 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 9/00 (20130101) C09K 9/02 (20130101) C09K 2211/1491 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/153 (20130101) G02F 1/15165 (20190101) G02F 2001/1502 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0035 (20130101) H01L 51/0037 (20130101) H01L 51/0056 (20130101) H01L 51/0071 (20130101) H01L 51/0072 (20130101) H01L 51/0073 (20130101) H01L 51/0074 (20130101) H01L 51/424 (20130101) Original (OR) Class H01L 51/442 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476152 | Larson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jacoby Larson (La Mesa, California); Darren Powell (San Diego, California) |
| ABSTRACT | A method and system which enable the automatic adjustment of the rotational speed of a radar antenna in a radar system having a continuously rotating radar antenna based on where objects are being detected. The automatic adjustment of the rotational speed of the radar antenna is controlled by a controller integrated with the radar system and is based on the bearing of the emitting antenna relative to objects being detected. The method relies on continuously reading the angular position of the antenna and corresponding the presence of detected objects to this angular position so as to automatically adjust the speed of the antenna to slow down the antenna while it is directing wave signals towards detected targets and speed up the antenna while it is directing wave signals in a direction where there are no detected objects. |
| FILED | Friday, December 15, 2017 |
| APPL NO | 15/843128 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00201 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 2207/10044 (20130101) Antennas, i.e Radio Aerials H01Q 3/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476154 | Doane et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Jonathan Peter Doane (Arlington, Massachusetts); Glenn A. Brigham (Chelmsford, Massachusetts); Bradley T. Perry (Nashua, New Hampshire) |
| ABSTRACT | Described embodiments provide sidelobe cancellation for Simultaneous Transmit and Receive systems. The sidelobe cancellation system includes an array having a primary aperture and an auxiliary array. The auxiliary array includes a plurality of antenna elements disposed adjacent to at least one side of the primary aperture. Each element of the auxiliary array is coupled to a variable attenuator, a variable phase shifter or a variable true time delay unit. A controller tunes the auxiliary array to cancel sidelobes of the primary aperture by adaptively selecting an attenuation value of the variable attenuator, a phase shift value of the variable phase shifter and a time delay value of the variable true time delay unit for each element of the auxiliary array. The auxiliary array operates as an adaptive finite-impulse response (FIR) filter with each antenna element of the auxiliary array operating as an adaptive tap of the adaptive FIR filter. |
| FILED | Wednesday, August 05, 2015 |
| APPL NO | 15/301585 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/06 (20130101) G01S 7/2813 (20130101) G01S 13/346 (20130101) G01S 13/762 (20130101) G01S 2013/0254 (20130101) Antennas, i.e Radio Aerials H01Q 3/2635 (20130101) Original (OR) Class H01Q 21/29 (20130101) H01Q 25/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476469 | Gong et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | Board of Trustees of the Univsity of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Songbin Gong (Champaign, Illinois); Yong-Ha Song (Urbana, Illinois) |
| ABSTRACT | A micro-resonator includes a first electrode positioned on a piezoelectric plate at a first end of the piezoelectric plate, the first electrode including a first set of fingers and a second electrode positioned on the piezoelectric plate at a second end of the piezoelectric plate. The second electrode including a second set of fingers interdigitated with the first set of fingers with an overlapping distance without touching the first set of fingers, the overlapping distance being less than seven-tenths the length of one of the first set of fingers or the second set of fingers. At least one of the first end or the second end of the piezoelectric plate may define a curved shape. |
| FILED | Thursday, February 16, 2017 |
| APPL NO | 15/434829 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 3/02 (20130101) H03H 9/171 (20130101) H03H 9/564 (20130101) H03H 9/568 (20130101) H03H 9/02015 (20130101) H03H 9/02086 (20130101) Original (OR) Class H03H 9/02157 (20130101) H03H 9/02228 (20130101) H03H 9/02259 (20130101) H03H 9/02992 (20130101) H03H 2003/021 (20130101) H03H 2003/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476487 | Roy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Kaushik Roy (West Lafayette, Indiana); Mrigank Sharad (West Lafayette, Indiana) |
| ABSTRACT | An electronic comparison system includes input stages that successively provide bits of code words. One-shots connected to respective stages successively provide a first bit value until receiving a bit having a non-preferred value concurrently with an enable signal, and then provide a second, different bit value. An enable circuit provides the enable signal if at least one of the one-shots is providing the first bit value. A neural network system includes a crossbar with row and column electrodes and resistive memory elements at their intersections. A writing circuit stores weights in the elements. A signal source applies signals to the row electrodes. Comparators compare signals on the column electrodes to corresponding references using domain-wall neurons and store bit values in CMOS latches by comparison with a threshold. |
| FILED | Thursday, November 02, 2017 |
| APPL NO | 15/801535 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) Static Stores G11C 11/16 (20130101) G11C 11/54 (20130101) G11C 11/161 (20130101) G11C 11/1673 (20130101) G11C 11/1675 (20130101) G11C 11/1693 (20130101) G11C 13/0007 (20130101) G11C 13/0069 (20130101) G11C 15/02 (20130101) G11C 15/046 (20130101) Pulse Technique H03K 3/356104 (20130101) Original (OR) Class Coding; Decoding; Code Conversion in General H03M 1/38 (20130101) H03M 1/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476514 | Vaz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Xilinx, Inc. (San Jose, California) |
| ASSIGNEE(S) | Xilinx, Inc. (San Jose, California) |
| INVENTOR(S) | Bruno Miguel Vaz (Sao Domingos de Rana, Portugal); John E. McGrath (Cahir, Ireland); Conrado K. Mesadri (San Jose, California); Woon C. Wong (Dublin, California); Ali Boumaalif (Cork City Centre, Ireland); Christophe Erdmann (Dublin, Ireland); Brendan Farley (Donabate, Ireland) |
| ABSTRACT | An integrated circuit is described. The integrated circuit comprises a first portion having programmable resources; a second portion having hardened circuits including an analog-to-digital converter circuit configured to receive an input signal and generate an output signal; and a monitor circuit configured to receive an output signal generated by the analog-to-digital converter circuit; wherein the monitor circuit is configurable to control a calibration of the analog-to-digital converter circuit based upon signal characteristics of the output signal generated by the analog-to-digital converter circuit. A method of receiving data in an integrated circuit is also described. |
| FILED | Wednesday, May 30, 2018 |
| APPL NO | 15/992797 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/318519 (20130101) Coding; Decoding; Code Conversion in General H03M 1/1071 (20130101) H03M 1/1215 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 12/43 (20130101) H04L 12/433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476584 | Minelli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Giovanni Minelli (Monterey, California); Mark Karpenko (Salinas, California); Issac Michael Ross (Monterey, California) |
| ABSTRACT | A mission planning system for scheduling the operations of one or more ground stations in order to optimize overall system communications with a plurality of satellites. The mission planning system comprises a digital processor in communication with each ground station, with the digital processor acting to assess the benefits and penalties acting in the system as a whole over a given time horizon. A system-wide cost function evaluated by the processor generally compares resultant SNR and slewing penalties for achievable communications, and provides a control vector uj(t) for each ground station determined through an optimization process, in order that various physical constraints and weighting factors pertinent to an individual ground station may be incorporated and accommodated as the digital processor optimizes overall system communications. |
| FILED | Thursday, November 30, 2017 |
| APPL NO | 15/827832 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/06 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) Transmission H04B 7/204 (20130101) H04B 7/18517 (20130101) H04B 7/18519 (20130101) Original (OR) Class H04B 17/18 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476678 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intelligent Fusion Technology, Inc (Germantown, Maryland) |
| ASSIGNEE(S) | INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland) |
| INVENTOR(S) | Yiran Xu (Germantown, Maryland); Gang Wang (Germantown, Maryland); Sixiao Wei (Germantown, Maryland); Genshe Chen (Germantown, Maryland); Khanh Pham (Germantown, Maryland); Erik Blasch (Germantown, Maryland) |
| ABSTRACT | Methods and systems for cyber secure data communications are provided. In some embodiments, a method for transmitting data comprises: performing a marker-based data encoding process to embed a digital watermark into each of a plurality of original data flows to be transmitted to a plurality of receivers; performing a non-orthogonal multiple access process to allocate transmission powers to the plurality of original data flows, such that the plurality of original data flows are simultaneously superposed on a carrier frequency to generate a superposed signal; performing a noise modulation process to modulate the superposed signal to generate a noise-like signal and a reference noise signal; transmitting the noise-like signal and the reference noise signal through orthogonally polarized antennas; and performing a portal-based data integrity analysis process to check whether a receiver in the plurality of receivers is compromised or manipulated. |
| FILED | Monday, March 27, 2017 |
| APPL NO | 15/469667 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Pulse Technique H03K 7/00 (20130101) H03K 9/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3247 (20130101) Original (OR) Class H04L 27/00 (20130101) H04L 63/123 (20130101) H04L 63/0823 (20130101) Wireless Communication Networks H04W 12/04 (20130101) H04W 28/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476872 | McLaren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Mitchell Leigh McLaren (Sunnyvale, California); Aaron Dennis Lawson (San Jose, California) |
| ABSTRACT | A spoken command analyzer computing system includes technologies configured to analyze information extracted from a speech sample and, using a joint speaker and phonetic content model, both determine whether the analyzed speech includes certain content (e.g., a command) and to identify the identity of the human speaker of the speech. In response to determining that the identity matches the authorized user's identity and determining that the analyzed speech includes the modeled content (e.g., command), an action corresponding to the verified content (e.g., command) is performed by an associated device. |
| FILED | Tuesday, February 02, 2016 |
| APPL NO | 15/013580 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/16 (20130101) G10L 15/22 (20130101) G10L 15/183 (20130101) G10L 17/18 (20130101) G10L 17/22 (20130101) G10L 2015/223 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/10 (20130101) H04L 63/0861 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10477178 | Leonard et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | John Joseph Leonard (Newton, Massachusetts); Sudeep Pillai (Cambridge, Massachusetts) |
| ABSTRACT | A tunable and iterative stereo mapping technique is provided, capable of identifying disparities at or substantially faster than real-time (e.g., frame-rate of 120 Hz). The method includes identifying a plurality of points in an image, determining disparity values for each of the points in the image and generating a piece-wise planar mesh based on the points and their respective disparity values. A disparity interpolation can be performed on candidate planes using estimated plane parameters for the candidate planes and a disparity image can be generated having a plurality of regions based on the disparity interpolation. Multiple iterations can be performed until the image is reconstructed with an appropriate resolution based on predetermined thresholds. The thresholds can be modified to provide a tunable system by changing the threshold values to either increase a resolution of a final reconstructed image and/or increase a computation speed of the tunable and iterative stereo mapping technique. |
| FILED | Thursday, June 29, 2017 |
| APPL NO | 15/637499 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/593 (20170101) G06T 17/20 (20130101) G06T 2207/10012 (20130101) Pictorial Communication, e.g Television H04N 13/111 (20180501) Original (OR) Class H04N 13/239 (20180501) H04N 2013/0081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10477665 | Hadidi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kamal Hadidi (Somerville, Massachusetts); Makhlouf Redjdal (Storrs-Mansfield, Connecticut) |
| ASSIGNEE(S) | AMASTAN TECHNOLOGIES INC. (North Andover, Massachusetts) |
| INVENTOR(S) | Kamal Hadidi (Somerville, Massachusetts); Makhlouf Redjdal (Storrs-Mansfield, Connecticut) |
| ABSTRACT | A microwave plasma torch providing two laminar flows is described. Two laminar flows are created using a set of at least three concentric, staggered dielectric tubes connected to a pressurized gas source. An inner laminar flow entrains injected particles entering the plasma. An outer laminar flow creates a sheath around the plasma and prevents it from attaching to the walls of the plasma torch. The entry point of the gas source is designed to ensure laminar flow for both the entrainment of the particles and for the shielding of the plasma plume. The uniform processing conditions results in uniform particles and a homogenous materials distribution. This enables a final product with improved thermal properties, improved corrosion and wear resistance and a higher tolerance to interface stresses. The microwave plasma torch can be used for producing nanomaterial powder and for spray coating materials onto various substrates. |
| FILED | Friday, April 13, 2012 |
| APPL NO | 13/445947 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10471409 | Krauss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Todd D. Krauss (Pittsford, New York); Richard Eisenberg (Rochester, New York); Patrick Holland (New Haven, Connecticut); Fen Qiu (Rochester, New York); Zhiji Han (Rochester, New York) |
| ABSTRACT | Provided are compositions for and methods of producing hydrogen. For example, the compositions comprise nanocrystals, a catalyst, a source of electrons, and an aqueous medium. The nanocrystals, catalyst, aqueous medium, and, optionally, the source of electrons are present as a mixture. The methods produce hydrogen by exposing the compositions to electromagnetic radiation (e.g., solar flux). |
| FILED | Tuesday, November 05, 2013 |
| APPL NO | 14/439304 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/122 (20130101) Original (OR) Class B01J 23/755 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/06 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471543 | Demos |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livemore, California) |
| INVENTOR(S) | Stavros G. Demos (Livermore, California) |
| ABSTRACT | Laser additive manufacturing apparatus, systems, and methods for the fabrication of high quality freeform high value structures. The apparatus, systems, and methods utilize a material powder having varying particle size and shape as raw material. It can also be adopted to use a wire as the feed material. |
| FILED | Tuesday, December 15, 2015 |
| APPL NO | 14/969190 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/342 (20151001) Original (OR) Class B23K 26/0604 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472286 | Jordan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Eric H Jordan (Storrs, Connecticut); Maurice Gell (Somerset, New Jersey); Rishi Kumar (Ashford, Connecticut); Chen Jiang (Willimantic, Connecticut) |
| ABSTRACT | Embodiments of a microstructure that allows arrest of contaminant infiltration includes an inter layer and at least one highly reactive ceramic layer. The inter layer is not reactive to an infiltrating reactive species. The HRC layer includes materials that react with a reactive contaminant species to slow or arrest infiltration of such contaminant species. |
| FILED | Wednesday, February 10, 2016 |
| APPL NO | 15/040871 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 18/00 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/0025 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2006/37 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/505 (20130101) Original (OR) Class C04B 2235/79 (20130101) C04B 2235/3222 (20130101) C04B 2235/3225 (20130101) C04B 2237/34 (20130101) C04B 2237/343 (20130101) C04B 2237/348 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472303 | Krause et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois); Illinois Institute of Technology (Chicago, Illinois) |
| INVENTOR(S) | Theodore R. Krause (Naperville, Illinois); Adam S. Hock (Chicago, Illinois); Guanghui Zhang (Naperville, Illinois); Yunjie Xu (Chicago, Illinois) |
| ABSTRACT | Methods, compositions, and articles of manufacture for alkane activation with single- or bi-metallic catalysts on crystalline mixed oxide supports. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 15/691666 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/08 (20130101) B01J 23/002 (20130101) B01J 23/10 (20130101) B01J 23/28 (20130101) B01J 23/42 (20130101) B01J 23/62 (20130101) B01J 23/75 (20130101) B01J 23/462 (20130101) B01J 23/468 (20130101) B01J 23/862 (20130101) B01J 23/6525 (20130101) B01J 23/6527 (20130101) B01J 23/6567 (20130101) B01J 23/8913 (20130101) B01J 35/023 (20130101) B01J 37/18 (20130101) B01J 37/088 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/24 (20130101) B01J 2523/24 (20130101) B01J 2523/24 (20130101) B01J 2523/24 (20130101) B01J 2523/24 (20130101) B01J 2523/24 (20130101) B01J 2523/24 (20130101) B01J 2523/32 (20130101) B01J 2523/67 (20130101) B01J 2523/67 (20130101) B01J 2523/67 (20130101) B01J 2523/67 (20130101) B01J 2523/67 (20130101) B01J 2523/67 (20130101) B01J 2523/67 (20130101) B01J 2523/68 (20130101) B01J 2523/74 (20130101) B01J 2523/821 (20130101) B01J 2523/828 (20130101) B01J 2523/828 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/842 (20130101) B01J 2523/845 (20130101) B01J 2523/3706 (20130101) B01J 2523/3706 (20130101) B01J 2523/3706 (20130101) B01J 2523/3706 (20130101) B01J 2523/3706 (20130101) B01J 2523/3706 (20130101) B01J 2523/3706 (20130101) B01J 2523/3712 (20130101) Acyclic or Carbocyclic Compounds C07C 2/76 (20130101) Original (OR) Class C07C 2/76 (20130101) C07C 11/04 (20130101) C07C 2521/08 (20130101) C07C 2523/10 (20130101) C07C 2523/28 (20130101) C07C 2523/46 (20130101) C07C 2523/62 (20130101) C07C 2523/75 (20130101) C07C 2523/86 (20130101) C07C 2523/89 (20130101) C07C 2523/656 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472355 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | Texas Tech University System (Lubbock, Texas) |
| INVENTOR(S) | Ruiwen Zhang (Amarillo, Texas); Wei Wang (Amarillo, Texas) |
| ABSTRACT | An SP-141 compound is a novel small molecule that can serve as a molecular-targeted chemotherapeutic agent. In one embodiment, the labeled compound can comprise SP-141, which comprises 6-methoxy-1-(naphthalen-1-yl)-9 H-pyrido[3,4-b]indote. The compound inhibits expression of oncogenes such as the Mouse Double Minute 2 protein. The compound can bind directly to Mouse Double Minute 2 to inhibit cancer growth including breast cancer growth. |
| FILED | Friday, September 25, 2015 |
| APPL NO | 15/513882 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472571 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Ji-Guang Zhang (Richland, Washington); Shuru Chen (Richland, Washington); Wu Xu (Richland, Washington) |
| ABSTRACT | Low flammability and nonflammable localized superconcentrated electrolytes (LSEs) for stable operation of electrochemical devices, such as rechargeable batteries, supercapacitors, and sensors, are disclosed. Electrochemical devices, such as rechargeable batteries, supercapacitors, and sensors, including the low flammability and nonflammable LSEs are also disclosed. The low flammability and nonflammable LSEs include an active salt, a solvent comprising a flame retardant compound, wherein the active salt is soluble in the solvent, and a diluent in which the active salt is insoluble or poorly soluble. In certain embodiments, such as when the solvent and diluent are immiscible, the LSE further includes a bridge solvent. |
| FILED | Thursday, October 19, 2017 |
| APPL NO | 15/788188 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 21/12 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/405 (20130101) H01M 10/056 (20130101) H01M 2004/8684 (20130101) H01M 2300/0028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472643 | Wei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Chia-Lin Wei (West Hartford, Connecticut); Chew Yee Ngan (West Hartford, Connecticut); Chee Hong Wong (West Hartford, Connecticut); Cindy Choi (San Ramon, California) |
| ABSTRACT | We identified 17 transcription factor genes that regulate lipid production and activity in an organism. We subsequently detailed characterization of one of them (psr1). Constructs, methods and systems for enhancing or increasing lipid production in an organism are described. |
| FILED | Monday, December 17, 2018 |
| APPL NO | 16/222970 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Peptides C07K 14/405 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472653 | Dietrich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lygos, Inc. (Berkeley, California) |
| ASSIGNEE(S) | Lygos, Inc. (Berkeley, California) |
| INVENTOR(S) | Jeffrey A. Dietrich (Berkeley, California); Jeffrey L. Fortman (Berkeley, California); Eric J. Steen (Berkeley, California) |
| ABSTRACT | Systems and methods for the production of malonate in recombinant host cells. |
| FILED | Monday, June 19, 2017 |
| APPL NO | 15/627191 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 51/38 (20130101) C07C 67/08 (20130101) C07C 67/08 (20130101) C07C 67/31 (20130101) C07C 67/31 (20130101) C07C 69/38 (20130101) C07C 69/675 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/46 (20130101) Original (OR) Class Enzymes C12Y 301/02004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472670 | Hungate et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona) |
| INVENTOR(S) | Bruce Hungate (Flagstaff, Arizona); Egbert Schwartz (Flagstaff, Arizona); Rebecca Mau (Flagstaff, Arizona); Jane Marks (Flagstaff, Arizona) |
| ABSTRACT | Methods modifying conventional SIP so that isotopic incorporation into the genomes of individual microbial taxa can be quantified are described. Further, methods to quantify the baseline densities of the DNA of individual microbial taxa without exposure to isotope tracers and then to quantify the change in DNA density of each taxon caused by isotope incorporation are described. The distribution of DNA of each taxon along a density gradient reflects the influence of isotope incorporation only, without reflecting the guanine-plus-cytosine content. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/640028 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1003 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6851 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2563/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472973 | Dutta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Sandip Dutta (Greenville, South Carolina); James Zhang (Greenville, South Carolina); Gary Michael Itzel (Simpsonville, South Carolina); John McConnell Delvaux (Fountain Inn, South Carolina); Matthew Troy Hafner (Honea Path, South Carolina) |
| ABSTRACT | A turbine component includes a root and an airfoil extending from the root to a tip opposite the root. The airfoil forms a leading edge and a trailing edge portion extending to a trailing edge. Radial cooling channels in the trailing edge portion of the airfoil permit radial flow of a cooling fluid through the trailing edge portion. Each radial cooling channel has a first end at a lower surface at a root edge of the trailing edge portion or at an upper surface at a tip edge of the trailing edge portion and a second end opposite the first end at the lower surface or the upper surface. A method of making a turbine component and a method of cooling a turbine component are also disclosed. |
| FILED | Monday, June 06, 2016 |
| APPL NO | 15/174271 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) F01D 5/187 (20130101) Original (OR) Class F01D 5/282 (20130101) F01D 9/02 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/30 (20130101) F05D 2230/22 (20130101) F05D 2230/31 (20130101) F05D 2230/237 (20130101) F05D 2240/122 (20130101) F05D 2240/304 (20130101) F05D 2250/183 (20130101) F05D 2250/184 (20130101) F05D 2250/185 (20130101) F05D 2260/20 (20130101) F05D 2260/204 (20130101) F05D 2300/175 (20130101) F05D 2300/6033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473175 | Wild et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Ronald Lee Wild (Albuquerque, New Mexico); Brad Boyce (Albuquerque, New Mexico); Audrey Morris-Eckart (Albuquerque, New Mexico) |
| ABSTRACT | Extension springs that can be manufactured to a small size with a precise free length are described herein. An extension spring comprises a first drawbar member and a second drawbar member that extend along a same direction. The extension spring further comprises a compression spring coil that surrounds respective portions of the draw bar members. At either end of the spring coil are positioned end caps that surround the drawbar members. The end caps provide flat surfaces on which the ends of the spring coil rest in a resting position of the extension spring. The end caps are held against bent ends of arms of the drawbar members by tension of the spring coil. When the drawbar members are drawn apart from one another, the end caps compress the spring coil. Compression of the spring coil causes forces that resist the motion of the drawbar members apart from one another. |
| FILED | Monday, March 19, 2018 |
| APPL NO | 15/924572 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Springs; Shock-absorbers; Means for Damping Vibration F16F 1/126 (20130101) Original (OR) Class F16F 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473474 | Rajagopalan et al. |
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| FUNDED BY |
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| APPLICANT(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Sal S. V. Rajagopalan (Bloomfield Hills, Michigan); Eric Wood (Arvada, Colorado); Jeff Gonder (Arvada, Colorado) |
| ABSTRACT | In various embodiments the present disclosure provides a system and a method for estimating energy usage in a vehicle. The system includes hardware that perform certain operations that include receiving data associated with a route to be taken by the vehicle. The operations include determining, based on the data associated with the route and a state of the vehicle, an estimate corresponding to the energy that would be used by the vehicle when traversing a segment of the route. |
| FILED | Friday, October 03, 2014 |
| APPL NO | 15/027130 |
| ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3469 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473552 | Leathe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Nicholas Leathe (Albuquerque, New Mexico); Nicolas Argibay (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to an additively manufactured (AM), monolithic, multi-axis linear flexural cantilever test artifact. The artifact is monolithic in that is it one continuous part with no assembly. The artifact can be non-destructively evaluated and includes a support frame, cantilevers, and a mount. |
| FILED | Wednesday, April 11, 2018 |
| APPL NO | 15/950905 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 2003/1057 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/00 (20141201) B33Y 50/02 (20141201) B33Y 70/00 (20141201) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 7/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473592 | Kramer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | David Kramer (Okemos, Michigan); Jin Chen (Lexington, Kentucky); Elisabeth Ostendorf (East Lansing, Michigan); Lei Xu (East Lansing, Michigan); Jeffrey Cruz (Okemos, Michigan); Jeremy J. Brodersen (Grand Rapids, Michigan) |
| ABSTRACT | Methods of determining and characterizing photosynthesis in plant parts of one or more plants includes capturing a plurality of images of the plant parts of the one or more plants with a sensor are provided. Fluorescence of the plant parts of the one or more plants can be measured by storing a sensor image of observed fluorescence. Light absorbed by the plant parts of the one or more plants can be estimated by observing red and/or infrared reflectance of the plant parts. A characteristic of photosynthesis such as linear electron flow in plant parts of the one or more plants can be derived using the measured fluorescence of the plant parts, the reflectance and the light absorbed by the plant parts, and/or the three-dimensional model comprising the plant parts of the one or more plants. Related apparatus and systems are also provided. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/569570 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473625 | Findikoglu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico); Chevron U.S.A. Inc. (San Ramon, California) |
| ASSIGNEE(S) | Chevron U.S.A. Inc. (San Ramon, California); Triad National Security, LLC (Los Alamos, California) |
| INVENTOR(S) | Alp T. Findikoglu (Santa Fe, New Mexico); Dipen N. Sinha (Los Alamos, New Mexico); Daniel R. Chapman (Oakland, California) |
| ABSTRACT | Methods for detecting and monitoring changes in mechanical structures and in walls of pipes, vessels and storage tanks, using muitimode acoustic signal propagation and detection, are described. Acoustic signals having chosen amplitude-time-frequency characteristics excite multiple modes in the structure under investigation, are generated and received at a small number of accessible locations, such as the ends of pipes and the tops and bottoms of vessels and storage tanks, with the inspection region between transmit and receive transducers. Small mechanical changes lead to acoustic scattering and attenuation among the various modes, which are detectable as changes in received signal intensity. Such changes may include material loss, material conversion and material addition. Once the structure is characterized in a known condition, the present method may be used to monitor the structure at a later time to determine whether changes have taken place. Methods for effective temperature compensation are also described. In addition, various pipe geometries and complex pipe geometries involving elbows, flanges, and the like can be monitored. |
| FILED | Friday, August 12, 2016 |
| APPL NO | 15/751429 |
| ART UNIT | 2865 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/66 (20130101) G01F 1/74 (20130101) G01F 1/708 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/043 (20130101) Original (OR) Class G01N 29/46 (20130101) G01N 29/326 (20130101) G01N 29/343 (20130101) G01N 29/348 (20130101) G01N 29/449 (20130101) G01N 29/4409 (20130101) G01N 29/4463 (20130101) G01N 29/4472 (20130101) G01N 2291/011 (20130101) G01N 2291/0258 (20130101) G01N 2291/2634 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473636 | Adams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada, Reno (Reno, Nevada) |
| ASSIGNEE(S) | Board of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada (Reno, Nevada) |
| INVENTOR(S) | Jesse D. Adams (Reno, Nevada); Todd A. Sulchek (Atlanta, Georgia); Stuart C. Feigin (Reno, Nevada) |
| ABSTRACT | A disclosed chemical detection system for detecting a target material, such as an explosive material, can include a cantilevered probe, a probe heater coupled to the cantilevered probe, and a piezoelectric element disposed on the cantilevered probe. The piezoelectric element can be configured as a detector and/or an actuator. Detection can include, for example, detecting a movement of the cantilevered probe or a property of the cantilevered probe. The movement or a change in the property of the cantilevered probe can occur, for example, by adsorption of the target material, desorption of the target material, reaction of the target material and/or phase change of the target material. Examples of detectable movements and properties include temperature shifts, impedance shifts, and resonant frequency shifts of the cantilevered probe. The overall chemical detection system can be incorporated, for example, into a handheld explosive material detection system. |
| FILED | Monday, June 05, 2017 |
| APPL NO | 15/614331 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/00 (20130101) G01N 27/007 (20130101) G01N 29/022 (20130101) G01N 29/036 (20130101) G01N 33/0031 (20130101) G01N 33/0057 (20130101) G01N 33/227 (20130101) Original (OR) Class G01N 2291/0257 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473668 | Van Dam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); SOFIE BIOSCIENCES, INC. (Culver City, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); SOFIE BIOSCIENCES, INC. (Culver City, California) |
| INVENTOR(S) | R. Michael Van Dam (Los Angeles, California); Melissa Moore (Culver City, California); Brandon Maraglia (Culver City, California); Daniel Thompson (Culver City, California) |
| ABSTRACT | A self-shielded, bench-top radiochemistry system, including a radioactive isotope dispensing module configured to draw an isotope out of a vial and dispense one or more metered doses of the isotope to a concentration module that concentrates the metered dose into a droplet amount of isotope and a synthesizer module that delivers the droplet amount of isotope along with one or more reagents to an electrowetting on dielectrics (EWOD) chip to produce a radiolabeled molecule. |
| FILED | Friday, June 05, 2015 |
| APPL NO | 15/315369 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) A61B 6/48 (20130101) A61B 6/542 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) Original (OR) Class Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/015 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/0005 (20130101) Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473687 | Resnick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Paul J. Resnick (Albuquerque, New Mexico); Brian D. Homeijer (Albuquerque, New Mexico); Thomas A. Friedmann (Albuquerque, New Mexico); Michael Wiwi (Albuquerque, New Mexico) |
| ABSTRACT | A microelectromechanical systems (MEMS) accelerometer that has high sensitivity to motion along the z axis is discussed. The device includes two symmetrical sets of bilateral, diametrically opposed high aspect ratio flexures that tether a movable proof mass to the frame of the device. The flexures are designed in such a way as to restrict movement of the proof mass along the x and y axes but readily allow motion along the z axis. More specifically, when the device experiences an acceleration along the x or y axes, the proof mass is restricted from moving because some of the bilateral, diametrically opposed flexures are in compression and others are in tension. |
| FILED | Friday, May 12, 2017 |
| APPL NO | 15/594133 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/125 (20130101) Original (OR) Class G01P 2015/0837 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473755 | Doerry |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Armin W. Doerry (Albuquerque, New Mexico) |
| ABSTRACT | Various technologies pertaining to motion compensation for radar systems using FM waveforms are described herein. A waveform generator outputs a parametrized, pulsed FM waveform to a radar antenna, whereupon the radar antenna emits pulsed electromagnetic (EM) radiation into a target area based upon the parametrized FM waveform. The parametrized FM waveform compensates for motion of a radar platform that includes the antenna. The parametrized FM waveform compensates for inter-pulse Doppler effects by introducing a time delay to a reference FM waveform, and compensates for intra-pulse Doppler effects by time dilating, or frequency-scaling, pulses of the reference waveform. The parametrized FM waveform can be generated by modifying the reference waveform based on first and second parameters, where the parameters are based upon motion of the radar platform and changes in echo return delay times from one pulse to another. |
| FILED | Tuesday, February 21, 2017 |
| APPL NO | 15/438024 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/2813 (20130101) Original (OR) Class G01S 13/93 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473818 | Rieker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado); Government of the United States of America as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Government of the United States of America as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| INVENTOR(S) | Gregory B. Rieker (Boulder, Colorado); Ian Coddington (Boulder, Colorado); Nathan R. Newbury (Boulder, Colorado); Kuldeep Prasad (Vienna, Virginia); Anna Karion (Bethesda, Maryland) |
| ABSTRACT | A system for detecting gas leaks and determining their location and size. A data gathering portion of the system utilizes a hub and spoke configuration to collect path-integrated spectroscopic data over multiple open paths around an area. A processing portion of the system applies a high-resolution transport model together with meteorological data of the area to generate an influence function of possible leak locations on gas detector measurement paths, and applies an inversion model to the influence function and the spectroscopic data to generate gas source size and location. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/263540 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/202 (20130101) Meteorology G01W 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474575 | Beard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARM Ltd (Cambridge, United Kingdom) |
| ASSIGNEE(S) | Arm Limited (Cambridge, United Kingdom) |
| INVENTOR(S) | Jonathan Curtis Beard (Austin, Texas); Eric Van Hensbergen (Austin, Texas) |
| ABSTRACT | A virtual link buffer provides communication between processing threads or cores. A first cache is accessible by a first processing device and a second cache accessible by a second processing device. An interconnect structure couples between the first and second caches and includes a link controller. A producer cache line in the first cache stores data produced by the first processing device and the link controller transfers data in the producer cache line to a consumer cache line in the second cache. Each new data element is stored at a location in the producer cache line indicated by a store position or tail indicator that is stored at a predetermined location in the same cache line. Transferred data are loaded from a location in the consumer cache line indicated by a load position or head indicator that is stored at a predetermined location in the same consumer cache line. |
| FILED | Monday, April 10, 2017 |
| APPL NO | 15/483036 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1064 (20130101) G06F 12/0813 (20130101) G06F 12/0831 (20130101) Original (OR) Class G06F 12/0833 (20130101) G06F 12/0875 (20130101) G06F 12/1054 (20130101) G06F 13/1668 (20130101) G06F 13/4282 (20130101) G06F 2212/60 (20130101) G06F 2212/68 (20130101) G06F 2212/621 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10475710 | Guo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Peijun Guo (Woodridge, Illinois); Richard D. Schaller (Clarendon Hills, Illinois) |
| ABSTRACT | A dielectric-coating based technique determines the refractive index of small dimension materials. The technique utilizes a sample of the small dimension material coated with the dielectric and an uncoated sample, where reflectivity is determined for each. The real and imaginary components of the refractive index can be determined for the small-dimension material itself. |
| FILED | Friday, July 13, 2018 |
| APPL NO | 16/035330 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/41 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/324 (20130101) H01L 21/02636 (20130101) H01L 22/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476017 | Kanatzidis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Mercouri G. Kanatzidis (Wilmette, Illinois); Duyen H. Cao (Evanston, Illinois); Konstantinos Stoumpos (Chicago, Illinois) |
| ABSTRACT | Highly phase-pure, two-dimensional, multilayered organic-inorganic hybrid, halide perovskites are provided. Also provided are optoelectronic devices that incorporate the halide perovskites as photoactive materials. |
| FILED | Tuesday, October 11, 2016 |
| APPL NO | 15/767012 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 19/00 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/14 (20130101) C30B 29/12 (20130101) C30B 29/54 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0007 (20130101) H01L 51/0025 (20130101) H01L 51/0032 (20130101) H01L 51/4213 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476044 | Young et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ovonic Battery Company, Inc. (Rochester Hills, Michigan) |
| ASSIGNEE(S) | Ovonic Battery Company, Inc. (Rochester Hills, Michigan) |
| INVENTOR(S) | Kwo-hsiung Young (Troy, Michigan); Jean Nei (Southgate, Michigan); Tiejun Meng (Novi, Michigan) |
| ABSTRACT | Provided are sealed pouch-cell batteries that are alkaline batteries or non-aqueous proton-conducing batteries. A pouch cell includes a flexible housing such as is used for pouch cell construction where the housing is in the form of a pouch, a cathode comprising a cathode active material suitable for use in an alkaline battery, an anode comprising an anode active material suitable for use in an alkaline battery, an electrolyte that is optionally an alkaline or proton-conducting electrolyte, and wherein the pouch does not include or require a safety vent or other gas absorbing or releasing system. The batteries provided function contrary to the art recognized belief that such battery systems were impossible due to unacceptable gas production during cycling. |
| FILED | Tuesday, November 28, 2017 |
| APPL NO | 15/823779 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/0207 (20130101) Original (OR) Class H01M 2/0275 (20130101) H01M 4/32 (20130101) H01M 4/242 (20130101) H01M 10/30 (20130101) H01M 10/48 (20130101) H01M 10/345 (20130101) H01M 10/425 (20130101) H01M 10/4257 (20130101) H01M 2010/4271 (20130101) H01M 2300/0014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476111 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Xudong Wang (Middleton, Wisconsin); Qiang Pang (Madison, Wisconsin); Yingjin Wei (Changchun, China PRC) |
| ABSTRACT | An aqueous rechargeable zinc ion battery is provided, the battery comprising a cathode comprising a V3O7.H2O-graphene composite, the composite comprising a plurality of V3O7.H2O nanostructures in contact with graphene, an anode in electrical communication with the cathode, the anode comprising zinc, and an aqueous electrolyte between the cathode and the anode, the aqueous electrolyte comprising zinc ions and an ether of a type and at an amount selected to maximize a capacity retention value of the battery. |
| FILED | Monday, November 13, 2017 |
| APPL NO | 15/810903 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/48 (20130101) H01M 4/362 (20130101) H01M 4/624 (20130101) H01M 10/36 (20130101) Original (OR) Class H01M 2004/028 (20130101) H01M 2300/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476226 | Bayramian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Andrew James Bayramian (Manteca, California); Kenneth Manes (Brentwood, California); Robert J. Deri (Pleasanton, California); Al Erlandson (Livermore, California); John Caird (San Francisco, California); Mary Spaeth (Brentwood, California) |
| ABSTRACT | A laser amplifier module having an enclosure includes an input window, a mirror optically coupled to the input window and disposed in a first plane, and a first amplifier head disposed along an optical amplification path adjacent a first end of the enclosure. The laser amplifier module also includes a second amplifier head disposed along the optical amplification path adjacent a second end of the enclosure and a cavity mirror disposed along the optical amplification path. |
| FILED | Thursday, August 06, 2015 |
| APPL NO | 14/820375 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/005 (20130101) H01S 3/027 (20130101) H01S 3/0071 (20130101) H01S 3/0404 (20130101) H01S 3/0941 (20130101) H01S 3/1308 (20130101) H01S 3/2316 (20130101) H01S 3/2341 (20130101) Original (OR) Class H01S 3/08072 (20130101) H01S 3/09408 (20130101) H01S 3/09415 (20130101) H01S 3/10007 (20130101) H01S 3/10061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476269 | Peng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Fang Z. Peng (Okemos, Michigan); Shuitao Yang (Lansing, Michigan); Deepak Gunasekaran (East Lansing, Michigan) |
| ABSTRACT | A method for independent real and reactive power flow control without sensing receiving end voltage in a power flow controller (PFC) includes calculating a first reference phase angle, calculating a first reference voltage, modifying the first reference phase angle calculated using a first phasor modifier, calculating a first reference current for a first terminal, calculating a second reference phase angle for current through the first terminal, calculating a second reference voltage across a second CMI by subtracting voltages at the first terminal and a second terminal, and controlling the first CMI and the second CMI for controlling the power flow through the PFC. |
| FILED | Thursday, August 04, 2016 |
| APPL NO | 15/752503 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Systems for Regulating Electric or Magnetic Variables G05F 1/70 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/1807 (20130101) Original (OR) Class Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/4208 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476872 | McLaren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Mitchell Leigh McLaren (Sunnyvale, California); Aaron Dennis Lawson (San Jose, California) |
| ABSTRACT | A spoken command analyzer computing system includes technologies configured to analyze information extracted from a speech sample and, using a joint speaker and phonetic content model, both determine whether the analyzed speech includes certain content (e.g., a command) and to identify the identity of the human speaker of the speech. In response to determining that the identity matches the authorized user's identity and determining that the analyzed speech includes the modeled content (e.g., command), an action corresponding to the verified content (e.g., command) is performed by an associated device. |
| FILED | Tuesday, February 02, 2016 |
| APPL NO | 15/013580 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/16 (20130101) G10L 15/22 (20130101) G10L 15/183 (20130101) G10L 17/18 (20130101) G10L 17/22 (20130101) G10L 2015/223 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/10 (20130101) H04L 63/0861 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10477668 | Chase et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brian E. Chase (Aurora, Illinois); Ralph J. Pasquinelli (Batavia, Illinois); Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| INVENTOR(S) | Brian E. Chase (Aurora, Illinois); Ralph J. Pasquinelli (Batavia, Illinois) |
| ABSTRACT | A method, system, and apparatus for vector control of radio frequency signals in narrow band devices such as Super-conducting Radio Frequency (SRF) cavities driven by injection locked magnetrons using carrier amplitude modulation by spectral energy spreading via phase modulation comprises coupling a magnetron to a cavity associated with a particle accelerator and injection locking the magnetron. A modulated amplitude and modulated phase of a drive signal is provided to the magnetron powering the cavity associated with the particle accelerator by removing power from a carrier according to a modulation scheme and providing vector control of the cavity radio frequency vector. |
| FILED | Thursday, October 02, 2014 |
| APPL NO | 15/512264 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 25/50 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10470379 | Dong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Liang Dong (Ames, Iowa); Huawei Jiang (Ames, Iowa); Maneesha Aluru (Atlanta, Georgia) |
| ABSTRACT | Systems, methods, and apparatus for large scale, high throughput phenotyping of items including plants to derive environment/genetics correlations based on controlled variation of environment. Spatial and temporal resolution is improved by an integrated system that can use space efficiently yet concurrently process a large number of replicates but in varying environments. This is accomplished by using an array of miniature greenhouses, each in communication with one or more generators or regulators of an environmental factor that can be independently supplied and controlled to each miniature greenhouse. The controller also controls acquisition of data from each greenhouse as well as processing of that data into phenomic/genomic correlations. |
| FILED | Friday, June 12, 2015 |
| APPL NO | 14/738406 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Planting; Sowing; Fertilising A01C 1/02 (20130101) Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 9/14 (20130101) A01G 9/26 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/0016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10470675 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Xinyu Zhang (Madison, Wisconsin); Teng Wei (Madison, Wisconsin); Shu Wang (Chicago, Illinois); Anfu Zhou (Beijing, China PRC) |
| ABSTRACT | A wireless vibrometer employs an antenna array to significantly boost the signal-to-noise ratio of faint received signals twin small objects vibrating at acoustic frequencies. This technique may be used to provide an improved physiological monitor (such as a pulse detector) or for long-range eavesdropping using the emitted power from a cell phone or the like. |
| FILED | Friday, June 17, 2016 |
| APPL NO | 15/185692 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/02444 (20130101) Original (OR) Class Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/00 (20130101) Secret Communication; Jamming of Communication H04K 3/25 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10470799 | Rus et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Daniela Rus (Weston, Massachusetts); Shuhei Miyashita (Sheffield, United Kingdom); Dana Damian (Sheffield, United Kingdom) |
| ABSTRACT | Origami robots, and associated systems, methods of treatment, and methods of manufacture are provided. A system includes an origami robot encapsulated for ingestion by a patient, such as in a biocompatible material that is dissolvable or meltable within the gastrointestinal tract. A method of treatment includes delivering an origami robot in a folded position into a gastrointestinal tract of a patient, causing the origami robot to unfold within the gastrointestinal tract, and directing the origami robot to a site requiring treatment in the gastrointestinal tract. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 15/493956 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/52 (20130101) Original (OR) Class A61B 34/30 (20160201) A61B 34/72 (20160201) A61B 34/73 (20160201) A61B 2017/00004 (20130101) A61B 2017/00526 (20130101) A61B 2034/303 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/00 (20130101) A61M 2210/1042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471016 | Mooney et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David J. Mooney (Sudbury, Massachusetts); David A. Weitz (Bolton, Massachusetts); Stefanie Utech (Erlangen, Germany); Radivoje Prodanovich (Belgrade, Serbia); Esther Amstad (Lausanne, Switzerland); Raluca Ostafe (Aachen, Germany); Angelo S. Mao (Somerville, Massachusetts); Connie Chang Wilking (Bozeman, Montana); Huanan Wang (Dalian, China PRC) |
| ABSTRACT | The invention relates to microparticles comprising a crosslinked gel and methods for making and using same. |
| FILED | Thursday, March 08, 2018 |
| APPL NO | 15/915686 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1652 (20130101) A61K 9/5036 (20130101) Original (OR) Class A61K 9/5089 (20130101) A61K 35/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471273 | Segev et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Eran Segev (Pasadena, California); Laurent Moreaux (Pasadena, California); Trevor M. Fowler (Pasadena, California); Andrei Faraon (La Canada Flintridge, California); Michael L. Roukes (Pasadena, California) |
| ABSTRACT | A neural probe for light stimulation of a tissue is provided. The probe includes a base that has light supplying circuitry, and one or more elongated microsized shanks extending from the base. Each shank has a longitudinal axis and includes one or more waveguides extending along the shank's length, with the waveguides being optically connected to the light supplying circuitry. In addition, each of the waveguides is optically connected to a diffraction grating coupler that emits a light beam from the shank when light passes from the base through the waveguide and to the diffraction grating coupler. The emitted light beam has a propagation direction at a set angle relative to an axis that is substantially normal to the longitudinal axis of the shank. A method for stimulating a tissue using the neural probe is also provided. |
| FILED | Monday, October 17, 2016 |
| APPL NO | 15/295991 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0601 (20130101) Original (OR) Class A61N 5/0622 (20130101) A61N 2005/063 (20130101) A61N 2005/0612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471646 | Mead et al. |
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| FUNDED BY |
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| APPLICANT(S) | Joey L. Mead (Carlisle, Massachusetts); Carol M. F. Barry (Tyngsborough, Massachusetts); John Shearer (Franklin, Pennsylvania); Artee Panwar (Wilmington, Massachusetts); Jinde Zhang (Lowell, Massachusetts); Nischay Kodihalli Shivaprakash (Lowell, Massachusetts) |
| ASSIGNEE(S) | The University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Joey L. Mead (Carlisle, Massachusetts); Carol M. F. Barry (Tyngsborough, Massachusetts); John Shearer (Franklin, Pennsylvania); Artee Panwar (Wilmington, Massachusetts); Jinde Zhang (Lowell, Massachusetts); Nischay Kodihalli Shivaprakash (Lowell, Massachusetts) |
| ABSTRACT | Methods and systems for manufacturing re-entrant structures, such as the structures exhibiting superomniphobic characteristic, in a continuous, well-controlled, high-rate (mass production, volume) manner are disclosed. |
| FILED | Thursday, May 19, 2016 |
| APPL NO | 15/159428 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 59/04 (20130101) B29C 59/022 (20130101) Original (OR) Class B29C 2059/023 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/12 (20130101) B29K 2105/256 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471648 | Mather et al. |
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| FUNDED BY |
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| APPLICANT(S) | Patrick Mather (Oxford, Pennsylvania); Xiaofan Luo (Cleveland, Ohio); Andrew M. DiOrio (Windham, New Hampshire); Kyung-Min Lee (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Syracuse University (Syracuse, New York) |
| INVENTOR(S) | Patrick Mather (Oxford, Pennsylvania); Xiaofan Luo (Cleveland, Ohio); Andrew M. DiOrio (Windham, New Hampshire); Kyung-Min Lee (Wright-Patterson AFB, Ohio) |
| ABSTRACT | A functionally graded shape memory polymer (SMP) that has a range of transition temperatures that are spatially distributed in a gradient fashion within one single article. The SMP is formed by post-curing a pre-cured glassy SMP in a linear temperature gradient that imposes different vitrification temperature limits at different positions along the gradient. Utilizing indentation-based surface shape memory coupled with optical measurements of photoelastic response, the capability of this material to respond over a wide range of thermal triggers is correlated with the graded glass transition behavior. This new class of SMP offers great potential for such applications as passive temperature sensing and precise control of shape evolution during a thermally triggered shape recovery. |
| FILED | Wednesday, March 01, 2017 |
| APPL NO | 15/446487 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 61/06 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/12 (20130101) C08F 220/14 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 2280/00 (20130101) Compositions of Macromolecular Compounds C08L 33/04 (20130101) C08L 63/00 (20130101) C08L 71/02 (20130101) C08L 71/02 (20130101) C08L 75/04 (20130101) C08L 2205/05 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24479 (20150115) Y10T 428/24628 (20150115) Y10T 428/24983 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472229 | Wiesner et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ulrich Wiesner (Ithaca, New York); Michael Thompson (Ithaca, New York); Hitesh Arora (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University Cornell Center for Technology (Ithaca, New York) |
| INVENTOR(S) | Ulrich Wiesner (Ithaca, New York); Michael Thompson (Ithaca, New York); Hitesh Arora (Ithaca, New York) |
| ABSTRACT | A method for fabricating a nanostructure utilizes a templated monocrystalline substrate. The templated monocrystalline substrate is energetically (i.e., preferably thermally) treated, with an optional precleaning and an optional amorphous material layer located thereupon, to form a template structured monocrystalline substrate that includes the monocrystalline substrate with a plurality of epitaxially aligned contiguous monocrystalline pillars extending therefrom. The monocrystalline substrate and the plurality of epitaxially aligned contiguous monocrystalline pillars may comprise the same or different monocrystalline materials. The method provides the nanostructure where when the monocrystalline substrate and the plurality of epitaxial aligned contiguous monocrystalline pillars comprise different monocrystalline materials having a bulk crystal structure mismatch of up to about 10 percent, lattice mismatch induced crystal structure defects may be avoided interposed between the monocrystalline substrate and the plurality of epitaxially aligned contiguous monocrystalline pillars, which may have an irregular sidewall shape. |
| FILED | Friday, March 04, 2011 |
| APPL NO | 13/582525 |
| ART UNIT | 1781 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00031 (20130101) Original (OR) Class B81C 2201/0149 (20130101) B81C 2201/0169 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 1/023 (20130101) C30B 29/08 (20130101) C30B 29/605 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02381 (20130101) H01L 21/02532 (20130101) H01L 21/02603 (20130101) H01L 21/02642 (20130101) H01L 21/28518 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24372 (20150115) Y10T 428/24413 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472398 | Klapoetke et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of The University of Alberta (Edmonton, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of The University of Alberta (Edmonton, Alberta, Canada) |
| INVENTOR(S) | Nathan Klapoetke (Cambridge, Massachusetts); Brian Yichiun Chow (Cambridge, Massachusetts); Edward Boyden (Chestnut Hill, Massachusetts); Gane Ka-Shu Wong (Edmontn, Canada); Yongku Peter Cho (Cambridge, Massachusetts) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. |
| FILED | Monday, November 12, 2012 |
| APPL NO | 14/357635 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0661 (20130101) A61N 2005/0662 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) G01N 33/48728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472399 | Klapoetke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of the University of Alberta (Edmonton, Alberta, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Governors of The University of Alberta (Edmonton, Alberta, AB, Canada) |
| INVENTOR(S) | Nathan Klapoetke (Ashburn, Virginia); Brian Yichiun Chow (Cherry Hill, New Jersey); Edward Boyden (Chestnut Hill, Massachusetts); Gane Ka-Shu Wong (Edmonton, Canada); Yongku Peter Cho (Vernon, Connecticut) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/359875 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 41/0023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0661 (20130101) A61N 2005/0662 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) G01N 33/48728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472449 | Pugh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Coleen Pugh (Akron, Ohio); Sadhan C. Jana (Fairlawn, Ohio); Nicole Swanson (Stow, Ohio); Prasad Raut (Cuyahoga Falls, Ohio); Hamad Albehaijan (Copley, Ohio) |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Coleen Pugh (Akron, Ohio); Sadhan C. Jana (Fairlawn, Ohio); Nicole Swanson (Stow, Ohio); Prasad Raut (Cuyahoga Falls, Ohio); Hamad Albehaijan (Copley, Ohio) |
| ABSTRACT | Coupling agents useful for preparing vulcanized composition with filers such as silica and carbon black are provided. The coupling agents include fluorine substituted styrene compounds and styrene compounds containing a hydrocarbyloxysilane functional group. The coupling agents may be grafted onto polydiene polymers or added into a vulcanizable composition as an oligomer. The use of one or both of fluorine substituted styrene compounds and styrene compounds containing a hydrocarbyloxysilane functional group may improve the strength, rolling resistance, and/or cure rate of a vulcanized polymer compared to a vulcanized polymer without a coupling agent. |
| FILED | Tuesday, April 18, 2017 |
| APPL NO | 15/490298 |
| ART UNIT | 1768 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Vehicle Tyres Tyre Inflation; Tyre Changing or Repairing; Repairing, or Connecting Valves To, Inflatable Elastic Bodies in General; Devices or Arrangements Related to Tyres B60C 1/00 (20130101) B60C 1/0016 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 212/14 (20130101) C08F 230/08 (20130101) C08F 279/02 (20130101) Original (OR) Class C08F 279/02 (20130101) C08F 279/02 (20130101) C08F 2438/03 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/04 (20130101) C08K 3/36 (20130101) C08K 3/36 (20130101) C08K 3/36 (20130101) Compositions of Macromolecular Compounds C08L 51/003 (20130101) C08L 51/003 (20130101) C08L 51/04 (20130101) C08L 51/04 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/862 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472500 | Wu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Wenzhuo Wu (West Lafayette, Indiana); Ruoxing Wang (West Lafayette, Indiana) |
| ABSTRACT | The present disclosure generally relates chitosan-based biopolymers and chitosan biopolymer film based triboelectric nanogenerators generating voltage and current using the triboelectric effect. The chitosan-based biopolymer is a reaction product of at least a chitosan and an acid, and optionally one or more component selected from starch, lignin and/or glycerol. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/978236 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/28 (20130101) Compositions of Macromolecular Compounds C08L 3/02 (20130101) C08L 5/08 (20130101) Original (OR) Class C08L 2201/06 (20130101) C08L 2203/16 (20130101) C08L 2203/20 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/12 (20130101) Electric Machines Not Otherwise Provided for H02N 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472677 | Jamieson, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Translational Therapeutics, Inc. (Arlington, Massachusetts) |
| ASSIGNEE(S) | Translational Therapeutics, Inc. (Arlington, Massachusetts) |
| INVENTOR(S) | Gordon A. Jamieson, Jr. (Arlington, Massachusetts); Katherine L. B. Borden (St. Laurent, Canada); Biljana Culjkovic (Montreal, Canada); Alex Kentsis (New York, New York) |
| ABSTRACT | Provided are methods and compositions for inhibiting eukaryotic translation initiation factor eIF4E. Such methods and compositions may be used alone or in conjunction with other therapies, such as gene therapies, for inhibiting cell proliferation and/or treating cancer. |
| FILED | Wednesday, July 10, 2013 |
| APPL NO | 13/938510 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4196 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473152 | Alqasimi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ahmad Alqasimi (Tampa, Florida); Craig Lusk (Lutz, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Ahmad Alqasimi (Tampa, Florida); Craig Lusk (Lutz, Florida) |
| ABSTRACT | A linear element with two stable points, it can be used as trust element allows for change in length. It can transform structure from one shape to another thus allowing for morphable configuration. A new model is presented herein for a linear bi-stable compliant mechanism and design guidelines for its use. The mechanism is based on the crank-slider mechanism. This model takes into account the first mode of buckling and post-buckling behavior of a compliant segment to describe the mechanism's hi-stable behavior. The kinetic and kinematic equations, derived from the Pseudo-Rigid-Body Model, were solved numerically and are represented in plots. This representation allows the generation of step-by-step design guidelines. Because different applications may have different input requirements, two different design approaches are described herein with different parameters subsets as inputs. |
| FILED | Thursday, June 30, 2016 |
| APPL NO | 15/198627 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 7/06 (20130101) F16C 11/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473410 | Jaikumar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arvind Jaikumar (Rochester, New York); Satish G. Kandlikar (Rochester, New York) |
| ASSIGNEE(S) | Rochester Institute of Technology (Rochester, New York) |
| INVENTOR(S) | Arvind Jaikumar (Rochester, New York); Satish G. Kandlikar (Rochester, New York) |
| ABSTRACT | A boiling heat transfer unit includes a substrate having a heat exchange region including a plurality of nucleating regions adjacent to feeder channels, wherein adjacent nucleating regions are separated by the feeder channels at a distance whereby vapor formed in the nucleating regions is moved away from the nucleating regions influencing liquid flow through the feeder channels towards the nucleating regions thereby establishing continuous self-sustaining separate vapor and liquid pathways increasing heat transfer due to developing region heat transfer in the feeder channels and enhancing overall boiling performance. |
| FILED | Thursday, November 17, 2016 |
| APPL NO | 15/354500 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 2021/0028 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/12 (20130101) F28F 13/187 (20130101) Original (OR) Class F28F 2260/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473521 | Hayman et al. |
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| FUNDED BY |
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| APPLICANT(S) | University Corporation for Atmospheric Research (Boulder, Colorado) |
| ASSIGNEE(S) | University Corporation for Atmospheric Research (Boulder, Colorado) |
| INVENTOR(S) | Matthew Hayman (Boulder, Colorado); Scott Spuler (Westminster, Colorado) |
| ABSTRACT | A photon counting system is provided. The photon counting system comprises an analog domain and a digital domain in communication with the analog domain. A detector is configured to detect photons. An analog digital converter is provided in the digital domain, while an amplifier circuit is provided in the analog domain that is configured to receive the detector's output, wherein the amplifier circuit's output is in communication with the analog digital converter. The output of the analog digital converter is in communication with a signal processing system that may perform accumulation of signals and store them in memory. |
| FILED | Wednesday, April 05, 2017 |
| APPL NO | 15/479445 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) Original (OR) Class G01J 2001/442 (20130101) G01J 2001/446 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473736 | Notaro{hacek over (s)} et al. |
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| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| INVENTOR(S) | Branislav M. Notaro{hacek over (s)} (Fort Collins, Colorado); Milan M. Ilic (Belgrade, Serbia); Alexey A. Tonyushkin (Quincy, Massachusetts); Nada J. Sekeljic (Hillsboro, Oregon); Pranav S. Athalye (Fort Collins, Colorado) |
| ABSTRACT | Example devices and methods of MRI scanning are disclosed herein. In an example, an MRI scanning system may include a structure defining a bore within which a subject is to be positioned for scanning. The system may also include a magnet to generate a primary magnetic field within the bore parallel to a longitudinal axis of the bore, and a helical-antenna radio-frequency (RF) coil oriented along the longitudinal axis to surround the subject. In addition, the system may include an RF signal generator to drive the helical-antenna RF coil to generate a circularly polarized (CP) RF magnetic field perpendicular to the longitudinal axis, as well as an RF detector to detect a response signal generated by tissues of the subject in response to the CP RF magnetic field. Also included may be a computing system to create an image of the tissues of the subject based on the detected response signal. |
| FILED | Wednesday, November 04, 2015 |
| APPL NO | 14/932539 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/28 (20130101) G01R 33/583 (20130101) G01R 33/34046 (20130101) Original (OR) Class G01R 33/34053 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10473914 | Kreit et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University Of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Eric Kreit (Cincinnati, Ohio); John David Rudolph (Cincinnati, Ohio); Kenneth A. Dean (Phoenix, Arizona) |
| ABSTRACT | A method for manufacturing a freestanding film having at least one population of through holes cumulatively totaling at least 1% of the film area, wherein the standard deviation of hole diameters is less than 25% and a thickness less than 25 micrometers, The film provides a carrier substrate, a photo-curable material, a release agent and deposits a photo-curable material on the substrate, selectively curing the material and leaving uncured material in the pattern of holes, dissolving away the uncured material and removing the cured material from the carrier substrate. Methods and apparatus are described. |
| FILED | Monday, August 07, 2017 |
| APPL NO | 15/670438 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/003 (20130101) B32B 37/18 (20130101) B32B 37/1292 (20130101) B32B 38/0004 (20130101) B32B 2315/08 (20130101) B32B 2457/20 (20130101) Optical Elements, Systems, or Apparatus G02B 26/005 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/172 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474029 | Mirkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Fengwei Huo (Evanston, Illinois); Zijian Zheng (Kowloon, China PRC); Gengfeng Zheng (Ambler, Pennsylvania) |
| ABSTRACT | The disclosure relates to methods of printing indicia on a substrate using a tip array comprised of elastomeric, compressible polymers. The tip array can be prepared using conventional photolithographic methods and can be tailored to have any desired number and/or arrangement of tips. Numerous copies (e.g., greater than 15,000, or greater than 11 million) of a pattern can be made in a parallel fashion in as little as 40 minutes. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/257143 |
| ART UNIT | 2854 — Printing/Measuring and Testing |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/856 (20130101) Y10S 977/874 (20130101) Y10S 977/878 (20130101) Y10S 977/887 (20130101) Y10S 977/888 (20130101) Y10S 977/902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474134 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Qiang Sean Huang (Rancho Palos Verdes, California); He Luan (Los Angeles, California); Yuan Jin (Los Angeles, California) |
| ABSTRACT | Methods and systems for predicting deformation error and compensating for shape deviation in Additive Manufacturing (AM) techniques include, in one aspect, a method including: obtaining a deformation model for an AM machine; predicting deformation for the object using the deformation model applied to the 3D model; selecting an amount of deformation compensation to effect by minimizing deviation for the predicted deformation; and providing the selected amount of deformation compensation to modify the 3D model to compensate for deformation during creation by the AM machine. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/143358 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 67/00 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) Original (OR) Class G05B 2219/49023 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/265 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474690 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Ke Wang (Charlottesville, Virginia); Kevin Skadron (Charlottesville, Virginia); Elaheh Sadredini (Charlottesville, Virginia) |
| ABSTRACT | The present invention introduces the development of a flexible CPU-AP (Computer Processing Unit-Automata Processor) computing infrastructure for mining hierarchical patterns based on Apriori algorithm. A novel automaton design strategy, called linear design, is described to generate automata for matching and counting hierarchical patterns and apply it on SPM (Sequential Pattern Mining). In addition, another novel automaton design strategy, called reduction design, is described for the disjunctive rule matching (DRM) and counting. The present invention shows performance improvement of AP SPM and DRM solutions and broader capability over multicore and GPU (Graphics Processing Unit) implementations of GSP SPM, and shows that AP SPM and DRM solutions outperform state-of-the-art SPM algorithms SPADE and PrefixSpan (especially for larger datasets). |
| FILED | Friday, March 31, 2017 |
| APPL NO | 15/475819 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2465 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474927 | Yang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico); Yin Yang (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC. UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Yin Yang (Albuquerque, New Mexico) |
| ABSTRACT | Technologies are disclosed for precomputation of reduced deformable models. In such precomputation, a Krylov subspace iteration may be used to construct a series of inertia modes for an input mesh. The inertia modes may be condensed into a mode matrix. A set of cubature points may be sampled from the input mesh, and cubature weights of the set of cubature points may be calculated for each of the inertia modes in the mode matrix. A training dataset may be generated by iteratively adding training samples to the training dataset until a training error metric converges, wherein each training sample is generated from an inertia mode in the mode matrix and corresponding cubature weights. The reduced deformable model may be generated, including inertia modes in the training dataset and corresponding cubature weights. |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/757261 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6214 (20130101) G06K 9/6247 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 13/20 (20130101) G06T 17/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10475548 | Guo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Lingjie Jay Guo (Ann Arbor, Michigan); Cheng Zhang (Ann Arbor, Michigan) |
| ABSTRACT | Electrically conductive, thin, smooth films are provided that comprise silver (Ag) and a conductive metal, such as aluminum (Al), titanium (Ti), nickel (Ni), chromium (Cr), gold (Au), magnesium (Mg), tantalum (Ta), germanium (Ge) or combinations thereof. In other alternative variations, electrically conductive, thin, smooth films are provided that comprise gold (Au) or copper (Cu) and a conductive metal, such as aluminum (Al), titanium (Ti), nickel (Ni), chromium (Cr), gold (Au), magnesium (Mg), tantalum (Ta), germanium (Ge) or combinations thereof. Such materials have excellent electrical conductivity, may be ultra-thin, flexible, transparent, and have low optical loss. Assemblies incorporating such films and methods of making the films are also provided. The assemblies may be used in photovoltaic and light emitting devices with high power conversion efficiencies or optical meta-materials that exhibit high transmittance and homogeneous response, among others. |
| FILED | Friday, May 22, 2015 |
| APPL NO | 15/313927 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Alloys C22C 5/06 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/185 (20130101) C23C 14/351 (20130101) C23C 14/3464 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 1/023 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/1884 (20130101) H01L 31/022425 (20130101) H01L 31/022491 (20130101) H01L 33/42 (20130101) H01L 51/442 (20130101) H01L 2933/0016 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10475601 | Lang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jeffrey H. Lang (Sudbury, Massachusetts); Timothy M. Swager (Newton, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts); Farnaz Niroui (Ontario, Canada); Ellen Sletten (Los Angeles, California) |
| ABSTRACT | Devices comprising at least two electrodes with a layer disposed therebetween are disclosed. In some embodiments, the layer disposed therebetween may be an insulator. In some embodiments, the layer may be capable of being deformed. Deforming the layer may cause a change in one or more materials properties of the device, such as the electrical properties and/or the optical properties of the device. |
| FILED | Wednesday, November 09, 2016 |
| APPL NO | 15/774642 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/24 (20130101) Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 11/04 (20130101) H01H 13/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10475705 | Binzaid et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shuza Binzaid (San Antonio, Texas); Avadhoot Herlekar (San Antonio, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Shuza Binzaid (San Antonio, Texas); Avadhoot Herlekar (San Antonio, Texas) |
| ABSTRACT | Disclosed is a voltage regulator for an integrated circuit. The voltage regulator can be configured to regulate a supply voltage provided to the integrated circuit. The integrated circuit can operate a near threshold value irrespective of a magnitude of the supply voltage. The voltage regulator can include a single Field Effect Transistor (FET) based circuit. The single FET based circuit can be configured to regulate the supply voltage. |
| FILED | Monday, November 20, 2017 |
| APPL NO | 15/817716 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Systems for Regulating Electric or Magnetic Variables G05F 1/575 (20130101) Electric Digital Data Processing G06F 1/26 (20130101) G06F 1/28 (20130101) G06F 1/32 (20130101) G06F 1/3234 (20130101) Static Stores G11C 5/147 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/8238 (20130101) Original (OR) Class H01L 22/34 (20130101) H01L 27/0922 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476324 | Hosek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Persimmon Technologies Corporation (Wakefield, Massachusetts) |
| ASSIGNEE(S) | Persimmon Technologies Corporation (Wakefield, Massachusetts) |
| INVENTOR(S) | Martin Hosek (Lowell, Massachusetts); Sripati Sah (Wakefield, Massachusetts) |
| ABSTRACT | A hybrid field electric motor includes a rotor with a rotor core rotating about an axial axis and having a rotor surface with at least one sloping edge face and a radial edge face. The stator includes a stator core and radial pole faces spaced by a gap from the radial edge face of the rotor for radially directing flux into the rotor core. The stator has sloping pole faces spaced from the sloping edge face of the rotor core for flux directed into the rotor core at an angle between radial and axial. The rotor core and/or stator core are made of a soft magnetic composite material for flux in inure than one plane in the core(s). |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 13/799449 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 1/02 (20130101) H02K 1/14 (20130101) H02K 1/20 (20130101) H02K 1/32 (20130101) H02K 1/2706 (20130101) Original (OR) Class H02K 19/103 (20130101) H02K 21/24 (20130101) H02K 21/44 (20130101) H02K 21/125 (20130101) H02K 21/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476705 | Pekoz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Berker Pekoz (Tampa, Florida); Selcuk Kose (Tampa, Florida); Huseyin Arslan (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Berker Pekoz (Tampa, Florida); Selcuk Kose (Tampa, Florida); Huseyin Arslan (Tampa, Florida) |
| ABSTRACT | Adaptive windowing of insufficient cyclic prefix (CP) for joint minimization of intersymbol interference (ISI) and adjacent channel interference (ACI) is provided. The proposed subcarrier specific windowing scheme improves the signal-to-interference ratio (SIR) even when the cyclic prefix (CP) is insufficient. Average optimal window lengths depend only on the power density profiles (PDPs), and although instantaneous optimal window lengths depend on users' channel impulse responses (CIRs), fluctuation is little. Therefore, subcarrier specific windowing outperforms fixed windowing, even with outdated window lengths in the case of powerful interferers. |
| FILED | Monday, May 20, 2019 |
| APPL NO | 16/417009 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/1027 (20130101) H04B 2001/1045 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0007 (20130101) H04L 25/0212 (20130101) H04L 25/03019 (20130101) Original (OR) Class H04L 27/2607 (20130101) Wireless Communication Networks H04W 72/082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10477097 | Zheng |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Guoan Zheng (Vernon, Connecticut) |
| ABSTRACT | Instruments, assemblies and methods are provided for undertaking imaging techniques (e.g., microscopic imaging techniques). The present disclosure provides improved imaging techniques, equipment and systems. More particularly, the present disclosure provides advantageous microscopy/imaging assemblies with single-frame sample autofocusing using multi-LED illumination. The present disclosure provides for assemblies and methods for single-frame rapid sample autofocusing without a z-scan. Potential applications for the disclosed assemblies/methods include, without limitation, whole slide imaging, optical metrology, wafer inspection, DNA sequencing and other high-throughput imaging applications where the sample may need to be scanned over a large field of view. The assemblies/methods advantageously utilize multiple LEDs for sample illumination. A captured image includes multiple copies of the sample, and one can recover the distance between these copies. The distance is directly related to the defocus distance. |
| FILED | Tuesday, January 02, 2018 |
| APPL NO | 15/860229 |
| ART UNIT | 2483 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 7/365 (20130101) G02B 21/02 (20130101) G02B 21/06 (20130101) G02B 21/244 (20130101) G02B 21/245 (20130101) G02B 21/361 (20130101) G02B 21/362 (20130101) G02B 21/365 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Image Data Processing or Generation, in General G06T 3/20 (20130101) G06T 7/70 (20170101) G06T 2207/10048 (20130101) G06T 2207/10056 (20130101) G06T 2207/20081 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) H04N 5/2253 (20130101) H04N 5/2256 (20130101) H04N 5/23212 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10477178 | Leonard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | John Joseph Leonard (Newton, Massachusetts); Sudeep Pillai (Cambridge, Massachusetts) |
| ABSTRACT | A tunable and iterative stereo mapping technique is provided, capable of identifying disparities at or substantially faster than real-time (e.g., frame-rate of 120 Hz). The method includes identifying a plurality of points in an image, determining disparity values for each of the points in the image and generating a piece-wise planar mesh based on the points and their respective disparity values. A disparity interpolation can be performed on candidate planes using estimated plane parameters for the candidate planes and a disparity image can be generated having a plurality of regions based on the disparity interpolation. Multiple iterations can be performed until the image is reconstructed with an appropriate resolution based on predetermined thresholds. The thresholds can be modified to provide a tunable system by changing the threshold values to either increase a resolution of a final reconstructed image and/or increase a computation speed of the tunable and iterative stereo mapping technique. |
| FILED | Thursday, June 29, 2017 |
| APPL NO | 15/637499 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/593 (20170101) G06T 17/20 (20130101) G06T 2207/10012 (20130101) Pictorial Communication, e.g Television H04N 13/111 (20180501) Original (OR) Class H04N 13/239 (20180501) H04N 2013/0081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10470828 | Markvicka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Eric Markvicka (Ravenna, Nebraska); Tom Frederick (Omaha, Nebraska); Jack Mondry (Stillwater, Minnesota); Joe Bartels (Lincoln, Nebraska); Shane Farritor (Lincoln, Nebraska) |
| ABSTRACT | The various robotic medical devices include robotic devices that are disposed within a body cavity and positioned using a support component disposed through an orifice or opening in the body cavity. Additional embodiments relate to devices having arms coupled to a device body wherein the device has a minimal profile such that the device can be easily inserted through smaller incisions in comparison to other devices without such a small profile. Further embodiments relate to methods of operating the above devices. |
| FILED | Thursday, March 12, 2015 |
| APPL NO | 14/656109 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Original (OR) Class A61B 90/361 (20160201) A61B 2017/2906 (20130101) A61B 2018/00595 (20130101) A61B 2018/00982 (20130101) A61B 2034/302 (20160201) Technical Subjects Covered by Former US Classification Y10T 74/20317 (20150115) Y10T 74/20329 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471542 | Gradl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Paul R. Gradl (Owens Cross Roads, Alabama); William Brandsmeier (Owens Cross Roads, Alabama) |
| ABSTRACT | A base structure is clad and coolant channels are formed through the cladding and into the base structure. A line of tangency relative to the outer clad surface is defined for each point thereon. Linear rows of a metal feedstock are directed towards and deposited on the outer clad surface as a beam of weld energy is directed to the metal feedstock so-deposited. The metal feedstock is the same material as the cladding or one that is weld compatible therewith. A first angle between the metal feedstock so-directed and the line of tangency is maintained in a range of 20-90°. The beam is directed towards a portion of the linear rows such that less than 30% of the cross-sectional area of the beam impinges on a currently-deposited one of the linear rows. A second angle between the beam and the line of tangency is maintained in a range of 5-65°. |
| FILED | Tuesday, June 27, 2017 |
| APPL NO | 15/634756 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/34 (20130101) Original (OR) Class B23K 26/0823 (20130101) B23K 26/0884 (20130101) Jet-propulsion Plants F02K 9/972 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10471652 | Hofmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Douglas C. Hofmann (Altadena, California); John Paul C. Borgonia (Santa Fe Springs, California) |
| ABSTRACT | Systems and methods in accordance with embodiments of the invention implement additive manufacturing techniques that employ different sets of deposition characteristics and/or material formation characteristics during the additive manufacture of an object so as to strategically build up the object. In many embodiments, material used to build up an object is deposited at different deposition rates during the additive manufacture of the object, and the object is thereby strategically built up. In one embodiment, a method of additively manufacturing an object includes: depositing material onto a surface at a first deposition rate so as to define a first region of the object to be additively manufactured; and depositing material onto a surface at a second deposition rate so as to define a second region of the object to be additively manufactured; where the second deposition rate is different from the first deposition rate. |
| FILED | Monday, September 24, 2018 |
| APPL NO | 16/139959 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 23/003 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/20 (20170801) B29C 64/106 (20170801) Original (OR) Class B29C 64/112 (20170801) B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472383 | Benner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steven A Benner (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven A Benner (Gainesville, Florida) |
| ABSTRACT | This invention claims aqueous compositions that comprise triphosphates of 2′-deoxynucleoside derivatives that have, instead of a 3′-OH moiety, a 3′-ONH2 moiety; wherein said compositions contain less than 0.5 mole percent contaminating triphosphate having a 3′-OH moiety, as well as processes for providing such compositions. The compositions further must contain insubstantial amounts of hydroxylamine. |
| FILED | Thursday, March 16, 2017 |
| APPL NO | 15/460475 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) Original (OR) Class C07H 19/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10472470 | Kornfield et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Julia A. Kornfield (Pasadena, California); Ming-Hsin Wei (Pasadena, California) |
| ABSTRACT | Described herein are associative polymers capable of controlling a physical and/or chemical property of non-polar compositions and related compositions, methods and systems. Associative polymers herein described have a non-polar backbone and functional groups presented at ends of the non-polar backbone, with a number of the functional groups presented at the ends of the non-polar backbone formed by associative functional groups capable of undergoing an associative interaction with another associative functional group with an association constant (k) such that the strength of each associative interaction is less than the strength of a covalent bond between atoms and in particular less than the strength of a covalent bond between backbone atoms. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 15/913828 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2438/01 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/08 (20130101) C08G 83/00 (20130101) C08G 83/005 (20130101) Original (OR) Class C08G 83/008 (20130101) C08G 2261/63 (20130101) C08G 2261/64 (20130101) C08G 2261/72 (20130101) C08G 2261/132 (20130101) C08G 2261/418 (20130101) C08G 2261/1644 (20130101) C08G 2261/3323 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0008 (20130101) Compositions of Macromolecular Compounds C08L 101/02 (20130101) C08L 101/08 (20130101) C08L 101/025 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/195 (20130101) C10L 1/236 (20130101) C10L 1/1658 (20130101) C10L 10/02 (20130101) C10L 10/08 (20130101) C10L 2230/22 (20130101) C10L 2250/04 (20130101) Pipe-line Systems; Pipe-lines F17D 1/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10474772 | Bolander et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nathan Bolander (Idaho Falls, Idaho); Rajasekhar V. Pulikollu (Nashville, Tennessee); Behrooz Jalalahmadi (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Sentient Science Corporation (Buffalo, New York) |
| INVENTOR(S) | Nathan Bolander (Idaho Falls, Idaho); Rajasekhar V. Pulikollu (Nashville, Tennessee); Behrooz Jalalahmadi (Idaho Falls, Idaho) |
| ABSTRACT | A system and method for determining surface contact fatigue life may use a finite element method to determine when components, such as a power transmission component, may fail in operation. The method may generate a finite element model based on the material parameters related to a power transmission component, generate a surface pressure time history for a loading event based on one or more loading parameters, determine, based on the surface pressure time history for a loading event, a finite element solution that describes stress in the grain structure, calculate damage in the finite element solution using a damage model, and determine whether a damage threshold is exceeded. |
| FILED | Friday, September 14, 2012 |
| APPL NO | 13/617405 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Gearing F16H 2057/0087 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 13/022 (20130101) Electric Digital Data Processing G06F 17/18 (20130101) G06F 17/5018 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10475346 | Sheth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | USA as Represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Kapil S. Sheth (Campbell, California); Sebastian A. Gutierrez-Nolasco (San Jose, California) |
| ABSTRACT | Method of miles-in-trail passback restrictions for use in air traffic management. Miles-in-trail restrictions can be used as a traffic management initiative when downstream traffic congestion at airports or in sectors is anticipated. To successfully implement the miles-in-trail at airspace fixes or navigational aids, it is desired that restriction values be computed for passing back to upstream facilities at specific boundaries. This method incorporates traffic manager feedback, resulting in significant improvement in guidance. Additional operational considerations required by traffic managers to implement the passback restrictions, namely maximum ground delay and absorbable airborne delay, are used in this method. The method also includes the step of absorbing a small amount of ground and airborne delays which are sufficient to handle the imposed constraint. The method further includes the step of implementing the passback restrictions to provide traffic managers ways to alleviate traffic constraints for reducing excessive airborne delay for current traffic conditions. |
| FILED | Thursday, October 08, 2015 |
| APPL NO | 14/878956 |
| ART UNIT | 3691 — Business Methods - Finance/Banking/ Insurance |
| CURRENT CPC | Traffic Control Systems G08G 5/04 (20130101) G08G 5/0017 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476141 | Marrero-Fontanez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Victor J. Marrero-Fontanez (Greenbelt, Maryland); Cornelis F. DuToit (Ellicott City, Maryland) |
| ABSTRACT | An antenna system includes a reflector, an offset feed horn and a support platform. The reflector has a reflector surface. The reflector and offset feed horn are attached to the support platform. The offset feed horn transmits RF microwave energy toward the reflector surface. The antenna system further includes a turntable which has a single rotation axis. The turntable rotates about the antenna rotation axis. The support platform is attached to the turntable such that the turntable rotates the support platform. The reflector surface has a perturbed paraboloid geometrical shape that reflects most RF microwave energy along a beam peak pointing direction. The reflector surface reflects RF microwave energy towards the earth's surface in such a manner that the reflected RF microwave energy illuminates a narrow strip of the earth's surface from nadir to a point near the earth's horizon with substantially constant intensity. The offset feed horn is oriented and positioned such that it points away from the beam peak pointing direction. |
| FILED | Monday, September 25, 2017 |
| APPL NO | 15/714252 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/17 (20130101) H01P 1/171 (20130101) Antennas, i.e Radio Aerials H01Q 1/125 (20130101) H01Q 1/288 (20130101) Original (OR) Class H01Q 3/02 (20130101) H01Q 3/04 (20130101) H01Q 13/0258 (20130101) H01Q 15/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10477495 | Delin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Kevin A. Delin (Arcadia, California); Shannon Jackson (Pasadena, California) |
| ABSTRACT | A Sensor Web formed of a number of different sensor pods. Each of the sensor pods include a clock which is synchronized with a master clock so that all of the sensor pods in the Web have a synchronized clock. The synchronization is carried out by first using a coarse synchronization which takes less power, and subsequently carrying out a fine synchronization to make a fine sync of all the pods on the Web. After the synchronization, the pods ping their neighbors to determine which pods are listening and responded, and then only listen during time slots corresponding to those pods which respond. |
| FILED | Tuesday, June 07, 2016 |
| APPL NO | 15/175965 |
| ART UNIT | 2461 — Multiplex and VoIP |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 21/00 (20130101) Multiplex Communication H04J 3/0641 (20130101) Wireless Communication Networks H04W 40/24 (20130101) H04W 56/001 (20130101) Original (OR) Class H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10473931 | Browne |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SA Photonics, Inc. (Los Gatos, California) |
| ASSIGNEE(S) | SA Photonics, Inc. (Los Gatos, California) |
| INVENTOR(S) | Michael P. Browne (San Mateo, California) |
| ABSTRACT | A wide field of view night vision system is described. The system comprises a head attachment apparatus configured to attach to a user's head and a night vision subsystem. The night vision subsystem comprises one or more night vision image sensors attached to the head attachment apparatus. Each sensor receives input light and produces a digital image of the input light. A processor processes the digital image(s) to produce a wide-field image. The wide-field image spans at least 60 degrees of a user's horizontal field of view. A display and eyepiece attached to the head attachment apparatus receives and displays the wide-field image. The eyepiece is positionable between the display and the user's eye to image the wide-field image into the user's eye. |
| FILED | Tuesday, March 28, 2017 |
| APPL NO | 15/471359 |
| ART UNIT | 2485 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) Original (OR) Class G02B 2027/011 (20130101) G02B 2027/014 (20130101) G02B 2027/0123 (20130101) G02B 2027/0138 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) H04N 5/2258 (20130101) H04N 5/23238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10476324 | Hosek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Persimmon Technologies Corporation (Wakefield, Massachusetts) |
| ASSIGNEE(S) | Persimmon Technologies Corporation (Wakefield, Massachusetts) |
| INVENTOR(S) | Martin Hosek (Lowell, Massachusetts); Sripati Sah (Wakefield, Massachusetts) |
| ABSTRACT | A hybrid field electric motor includes a rotor with a rotor core rotating about an axial axis and having a rotor surface with at least one sloping edge face and a radial edge face. The stator includes a stator core and radial pole faces spaced by a gap from the radial edge face of the rotor for radially directing flux into the rotor core. The stator has sloping pole faces spaced from the sloping edge face of the rotor core for flux directed into the rotor core at an angle between radial and axial. The rotor core and/or stator core are made of a soft magnetic composite material for flux in inure than one plane in the core(s). |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 13/799449 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 1/02 (20130101) H02K 1/14 (20130101) H02K 1/20 (20130101) H02K 1/32 (20130101) H02K 1/2706 (20130101) Original (OR) Class H02K 19/103 (20130101) H02K 21/24 (20130101) H02K 21/44 (20130101) H02K 21/125 (20130101) H02K 21/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10470446 | Shen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Lanlan Shen (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure concern compositions and methods for genetic engineering related to hypermethylation of sequences. In particular embodiments, there are methods and compositions to induce DNA methylation in a manner that leads to transcriptional suppression of a target gene that allows characterization of the gene and/or its expression. |
| FILED | Thursday, May 21, 2015 |
| APPL NO | 15/312986 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 67/0278 (20130101) Original (OR) Class A01K 2217/072 (20130101) A01K 2267/03 (20130101) A01K 2267/0331 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10473818 | Rieker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado); Government of the United States of America as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Government of the United States of America as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| INVENTOR(S) | Gregory B. Rieker (Boulder, Colorado); Ian Coddington (Boulder, Colorado); Nathan R. Newbury (Boulder, Colorado); Kuldeep Prasad (Vienna, Virginia); Anna Karion (Bethesda, Maryland) |
| ABSTRACT | A system for detecting gas leaks and determining their location and size. A data gathering portion of the system utilizes a hub and spoke configuration to collect path-integrated spectroscopic data over multiple open paths around an area. A processing portion of the system applies a high-resolution transport model together with meteorological data of the area to generate an influence function of possible leak locations on gas detector measurement paths, and applies an inversion model to the influence function and the spectroscopic data to generate gas source size and location. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/263540 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/202 (20130101) Meteorology G01W 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10474816 | Hall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | William E. Hall (Clinton, Connecticut); Guerney D. H. Hunt (Yorktown Heights, New York); Ronald N. Kalla (Round Rock, Texas); Jentje Leenstra (Bondorf, Germany); Paul Mackerras (Weston, Australia); William J. Starke (Round Rock, Texas); Jeffrey A. Stuecheli (Austin, Texas) |
| ABSTRACT | A system, a method, and a computer program product for secure memory implementation for secure execution of virtual machines. Data is processed in a first mode and a second mode, and commands are sent to a chip interconnect bus using real addresses, wherein the chip interconnect bus transports a number of bits for the real addresses. A memory controller is operatively coupled to a memory component. A secure memory range is specified by using range registers. If the real address is detected to be in the secure memory range to match a memory component address, a real address bit is set. If the real address is in the memory address hole, a security access violation is detected. If the real address is not in the secure address range and the real address bit is set, the security access violation is detected. |
| FILED | Thursday, December 14, 2017 |
| APPL NO | 15/842279 |
| ART UNIT | 2495 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) G06F 12/1441 (20130101) G06F 13/364 (20130101) G06F 13/404 (20130101) G06F 21/53 (20130101) G06F 21/556 (20130101) Original (OR) Class G06F 21/6281 (20130101) G06F 2009/45587 (20130101) G06F 2212/1052 (20130101) G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10474035 | Tang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Cha-Min Tang (Wayne, Pennsylvania); Valentina Emiliani (Paris, France); Peter Pennefather (Toronto, Canada) |
| ABSTRACT | Systems and methods are provided that combine an amplitude modulation SLM with a phase modulating SLM in the same optical illumination system. The combination of the amplitude modulation SLM and the phase modulation SLM allows the optical illumination to compensate for the limitations of amplitude modulation SLM by using phase modulating SLM and conversely to compensate for the limitations of phase modulation SLM by using amplitude modulating SLM. |
| FILED | Wednesday, September 06, 2017 |
| APPL NO | 15/697369 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/135 (20170801) Optical Elements, Systems, or Apparatus G02B 13/0095 (20130101) G02B 21/06 (20130101) G02B 21/0024 (20130101) G02B 21/0076 (20130101) G02B 26/0833 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 21/005 (20130101) G03B 21/2033 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/70025 (20130101) Original (OR) Class G03F 7/70291 (20130101) G03F 7/70416 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0057 (20130101) H01S 3/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Treasury (TREASURY)
| US 10472674 | Esfandyarpour et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GenapSys, Inc. (Redwood City, California) |
| ASSIGNEE(S) | GENAPSYS, INC. (Redwood City, California) |
| INVENTOR(S) | Hesaam Esfandyarpour (Redwood City, California); Mark Oldham (Emerald Hills, California) |
| ABSTRACT | A method comprises magnetically holding a bead carrying biological material (e.g., nucleic acid, which may be in the form of DNA fragments or amplified DNA) in a specific location of a substrate, and applying an electric field local to the bead to isolate the biological material or products or byproducts of reactions of the biological material. For example, the bead is isolated from other beads having associated biological material. The electric field in various embodiments concentrates reagents for an amplification or sequencing reaction, and/or concentrates and isolates detectable reaction by-products. For example, by isolating nucleic acids around individual beads, the electric field can allow for clonal amplification, as an alternative to emulsion PCR. In other embodiments, the electric field isolates a nanosensor proximate to the bead, to facilitate detection of at least one of local pH change, local conductivity change, local charge concentration change and local heat. The beads may be trapped in the form of an array of localized magnetic field regions. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/360369 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 3/502761 (20130101) B01L 7/52 (20130101) B01L 2200/10 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2200/0689 (20130101) B01L 2300/12 (20130101) B01L 2300/089 (20130101) B01L 2300/123 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0887 (20130101) B01L 2400/043 (20130101) B01L 2400/0415 (20130101) B01L 2400/0418 (20130101) B01L 2400/0421 (20130101) B01L 2400/0424 (20130101) B01L 2400/0427 (20130101) B01L 2400/0478 (20130101) B01L 2400/0655 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/30 (20130101) B03C 1/286 (20130101) B03C 1/288 (20130101) B03C 5/005 (20130101) B03C 5/022 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 2523/307 (20130101) C12Q 2523/307 (20130101) C12Q 2523/307 (20130101) C12Q 2563/116 (20130101) C12Q 2563/116 (20130101) C12Q 2563/143 (20130101) C12Q 2563/143 (20130101) C12Q 2565/543 (20130101) C12Q 2565/543 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 60/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/40 (20130101) G01N 27/4145 (20130101) G01N 27/4146 (20130101) G01N 33/5438 (20130101) G01N 2001/4038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10474375 | Fleming, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kermin Elliott Fleming, Jr. (Hudson, Massachusetts); Simon C. Steely, Jr. (Hudson, New Hampshire); Kent D. Glossop (Nashua, New Hampshire) |
| ABSTRACT | An integrated circuit includes a processor to execute instructions and to interact with memory, and acceleration hardware, to execute a sub-program corresponding to instructions. A set of input queues includes a store address queue to receive, from the acceleration hardware, a first address of the memory, the first address associated with a store operation and a store data queue to receive, from the acceleration hardware, first data to be stored at the first address of the memory. The set of input queues also includes a completion queue to buffer response data for a load operation. A disambiguator circuit, coupled to the set of input queues and the memory, is to, responsive to determining the load operation, which succeeds the store operation, has an address conflict with the first address, copy the first data from the store data queue into the completion queue for the load operation. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/396049 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/065 (20130101) G06F 3/067 (20130101) G06F 3/0619 (20130101) Original (OR) Class G06F 9/3826 (20130101) G06F 9/3834 (20130101) G06F 9/30043 (20130101) G06F 12/00 (20130101) G06F 13/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10471475 | Stratton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Christopher M. Stratton (Springfield, Virginia); Gregory J. Smith (Arlington, Virginia); Thomas C. Potter (Oak Hill, Virginia) |
| ABSTRACT | Sorting systems and methods for large quantities of items in industrial processes are described. The systems, devices and methods are for receiving, sorting and removing items dynamically. A first group of items, such as letters or other mail pieces, are injected by a belt into a pocket to a form a first stack, and a divider is extended near the first stack. The divider allows for a second group of items to either be injected to form a second stack behind the divider, or to be diverted and injected into another pocket. The first stack can be removed while the second group is being injected. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/205837 |
| ART UNIT | 3659 — Material and Article Handling |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/00 (20130101) B07C 3/02 (20130101) B07C 3/06 (20130101) B07C 3/008 (20130101) B07C 3/18 (20130101) B07C 3/087 (20130101) Original (OR) Class B07C 5/00 (20130101) B07C 5/04 (20130101) B07C 5/38 (20130101) Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables B65H 43/00 (20130101) B65H 2301/43 (20130101) B65H 2301/432 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10472687 | Peterson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Institute for Systems Biology (Seattle, Washington) |
| ASSIGNEE(S) | Institute for Systems Biology (Seattle, Washington); Center for Infectious Disease Research (Seattle, Washington) |
| INVENTOR(S) | Eliza Peterson (Seattle, Washington); Nitin S. Baliga (Seattle, Washington) |
| ABSTRACT | Practical assays to identify compounds that overcome the resistance of M. tuberculosis to bedaquiline are based on transcription factors Rv0324 and Rv0880 shown to mediate this resistance. |
| FILED | Friday, January 06, 2017 |
| APPL NO | 16/068670 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6897 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/4703 (20130101) G01N 2800/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10477225 | Yadegar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UtopiaCompression Corporation (Los Angeles, California) |
| ASSIGNEE(S) | UtopiaCompression Corporation (Los Angeles, California) |
| INVENTOR(S) | Jacob Yadegar (Los Angeles, California); Hai Wei (Los Angeles, California); Joseph Yadegar (Los Angeles, California) |
| ABSTRACT | An encoding-decoding method and system is provided where the encoding process or system are not a mirror image of the decoding process or system. |
| FILED | Friday, June 20, 2014 |
| APPL NO | 14/311083 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 19/25 (20141101) H04N 19/30 (20141101) H04N 19/42 (20141101) Original (OR) Class H04N 19/65 (20141101) H04N 19/136 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
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This week's information is published in the FedInvent Patents report for Tuesday, November 12, 2019.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20191112.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page