FedInvent™ Patents
Patent Details for Tuesday, December 31, 2019
This page was updated on Monday, March 27, 2023 at 05:58 AM GMT
Department of Health and Human Services (HHS)
| US 10517477 | Grundfest et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Warren S. Grundfest (Los Angeles, California); Shijun Sung (Elk Grove, California); Zachary Taylor (Los Angeles, California) |
| ABSTRACT | Methods and systems for single beam scanning capable of imaging the surface of a spherical body of arbitrary radius of curvature are provided. The spherical imaging methods and systems utilize one or more off-axis parabolic (OAP) mirror to perform a geometrical transformation of the spherical surface to a flat rectilinear imaging coordinate grid such that the single scanning beam maintains a normal incidence across the curved field of view of the spherical body. The imaging methods and systems project the spherical surface to a Cartesian plane and then the remapped surface is rapidly imaged by raster-scanning an illumination beam in the rectangular coordinate such that the OAP mirror produces a rectilinear image of the target. The imaging of the spherical surface is accomplished while maintaining the target, illumination source, and detector in a stationary position. The imaging systems and methods may utilize a single source and a single detector, and may incorporate a THz illumination source. The beam scanning imaging systems and methods may be applied to corneal tissue imaging. |
| FILED | Tuesday, February 16, 2016 |
| APPL NO | 15/549973 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0008 (20130101) A61B 3/14 (20130101) A61B 3/107 (20130101) A61B 3/1025 (20130101) Original (OR) Class Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/2518 (20130101) Optical Elements, Systems, or Apparatus G02B 17/0832 (20130101) G02B 26/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517494 | Tereshchenko et al. |
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| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Johns Hopkins University (Baltimore, Maryland); Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Johns Hopkins University (Baltimore, Maryland); Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Larisa G. Tereshchenko (Portland, Oregon); Mark E. Josephson (Boston, Massachusetts) |
| ABSTRACT | A method and system for determining a patient's risk of ventricular tachycardia are disclosed. The method includes receiving ECG signals from a patient and filtering the collected ECG signals to generate filtered ECG signals. The method further includes identifying a heart vector from the filtered ECG signals, and measuring a velocity of the heart vector movement. A change in curvature of the identified heart vector movement is quantified and a risk of ventricular tachycardia is determined based at least on the measured velocity and the quantified change in curvature of the identified heart vector movement. |
| FILED | Friday, November 13, 2015 |
| APPL NO | 15/522615 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0464 (20130101) A61B 5/04011 (20130101) Original (OR) Class A61B 5/7264 (20130101) A61B 5/7275 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3622 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00557 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517513 | Vimegnon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yves Vimegnon (Portland, Oregon); Gregory Landry (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Yves Vimegnon (Portland, Oregon); Gregory Landry (Portland, Oregon) |
| ABSTRACT | Systems, devices and methods for quantitatively assessing hand function strength and range of motion via various instrumentations are disclosed. In one example embodiment, a hand function diagnostic and therapeutic system includes distal and proximal finger flexion measurement apparatuses used to automate quantitative assessment of hand function based on a combination of strength, range of motion, and time performance metrics. |
| FILED | Friday, October 30, 2015 |
| APPL NO | 14/927944 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/70 (20130101) A61B 5/1125 (20130101) Original (OR) Class A61B 5/1126 (20130101) A61B 2505/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517556 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Guang-Hong Chen (Madison, Wisconsin); Jie Tang (Madison, Wisconsin) |
| ABSTRACT | A method for increasing the temporal fidelity, increasing the temporal sampling density, and/or reducing the temporal noise of a series of image frames obtained with a medical imaging system is provided. The image frames are acquired with the medical imaging system. The medical imaging system may be, for example, an x-ray C-arm imaging system. A window function that is representative of a temporal fidelity window is selected and used to temporally deconvolve the image frames using a minimization technique. A temporal sampling density may also be selected and used in the temporal deconvolution. The resultant deconvolved image frames have a higher temporal fidelity to a time-varying image contrast depicted in the acquired image frames, and may also have an increased temporal sampling density and/or reduced temporal noise. |
| FILED | Friday, February 08, 2013 |
| APPL NO | 13/763593 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0037 (20130101) A61B 5/055 (20130101) A61B 5/0059 (20130101) A61B 5/7203 (20130101) A61B 5/7292 (20130101) A61B 6/025 (20130101) A61B 6/032 (20130101) A61B 6/52 (20130101) A61B 6/54 (20130101) A61B 6/461 (20130101) A61B 6/467 (20130101) A61B 6/481 (20130101) Original (OR) Class A61B 6/486 (20130101) A61B 6/507 (20130101) A61B 6/4085 (20130101) A61B 6/4441 (20130101) A61B 6/5217 (20130101) A61B 6/5258 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5601 (20130101) G01R 33/5602 (20130101) G01R 33/5608 (20130101) G01R 33/56325 (20130101) G01R 33/56366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517564 | Konofagou et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Elisa E. Konofagou (New York, New York); Jean Provost (Paris, France); Alok Gambhir (New York, New York); Alexandre Costet (New York, New York); Elaine Wan (Fresh Meadows, New York); Julien Grondin (Saint-Philippe, France) |
| ABSTRACT | Techniques for mapping behavior of a heart include acquiring a series of two or more images of the heart. The series of images is taken at one or more pixel locations, each pixel location corresponding to a region of the heart. Image data corresponding to the pixel locations can be obtained, and a periodicity of the image data measured for each of the pixel locations over the series of images. The periodicity corresponds to an electromechanical signal of the heart in the region corresponding to the measured one or more pixel locations. |
| FILED | Thursday, April 09, 2015 |
| APPL NO | 14/682980 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1102 (20130101) A61B 8/02 (20130101) A61B 8/463 (20130101) A61B 8/485 (20130101) A61B 8/0883 (20130101) Original (OR) Class A61B 8/5207 (20130101) A61B 8/5223 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52036 (20130101) G01S 7/52042 (20130101) G01S 7/52087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517565 | Zhu |
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| FUNDED BY |
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| APPLICANT(S) | The University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Quing Zhu (Mansfield, Connecticut) |
| ABSTRACT | An imaging system includes a primary probe that includes a substrate; an ultrasound transducer disposed in the substrate to irradiate a first tissue with an ultrasound frequency; a first near infrared source to irradiate the first tissue with a first near infrared wavelength; and a first light detector to detect a first detected wavelength from the first tissue; an auxiliary probe that includes a second near infrared source configured to irradiate a second tissue with a second near infrared wavelength; and a second light detector configured to detect a second detected wavelength from the second tissue. The system also can include an optical tomography device; an ultrasound device; and a processor unit. A process for imaging includes disposing the primary probe on a first tissue, disposing an auxiliary probe on a second tissue, irradiating the first tissue, and irradiating the second tissue to produce an image of the first tissue. |
| FILED | Thursday, July 25, 2013 |
| APPL NO | 15/028756 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0073 (20130101) A61B 8/14 (20130101) A61B 8/085 (20130101) A61B 8/463 (20130101) A61B 8/0825 (20130101) A61B 8/4416 (20130101) Original (OR) Class A61B 8/4444 (20130101) A61B 8/5223 (20130101) A61B 8/5261 (20130101) A61B 2090/3735 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517569 | Weitzel et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | William Weitzel (Ypsilanti, Michigan); Grant Kruger (Ann Arbor, Michigan); Brian Thelen (Ann Arbor, Michigan); Jonathan Rubin (Ann Arbor, Michigan); Leo Koziol (Canton, Michigan); Robert Brook (Canton, Michigan); Mainak Mitra (Ann Arbor, Michigan) |
| ABSTRACT | An ultrasound imaging system uses a magnetic linear motor driven ultrasound scanner, with accurate track and hold operation and/or other motion feedback, to scan a two dimensional or three dimensional area of a sample. The scanner is implemented in a low-power and low-bandwidth handheld device and is connected with a remote image processing system that receives raw data and performs full ultrasound image analysis and creation, allowing the handheld to be used for scanning, pre-processing, and display. |
| FILED | Thursday, May 09, 2013 |
| APPL NO | 13/890906 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/56 (20130101) A61B 8/461 (20130101) A61B 8/483 (20130101) A61B 8/488 (20130101) A61B 8/0891 (20130101) A61B 8/4427 (20130101) A61B 8/4461 (20130101) A61B 8/4472 (20130101) A61B 8/4483 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/222 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/003 (20130101) G01S 7/52042 (20130101) G01S 7/52065 (20130101) G01S 15/8915 (20130101) G01S 15/8945 (20130101) G01S 15/8995 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517731 | Vunjak-Novakovic et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Gordana Vunjak-Novakovic (New York, New York); Warren Grayson (New York, New York); Keith Yeager (Jersey City, New Jersey) |
| ABSTRACT | An anatomically-shaped, human bone graft may be cultivated ex vivo using a bioreactor capable of perfusing large complex porous scaffolds. Scaffolds derived from image-based modeling of a target are seeded with human mesenchymal stem cells and cultivated. A bioreactor configured to house complex three-dimensional scaffold geometries provides controlled flow for perfusion of the cells. Dense uniform cellular growth can be attained throughout the entire scaffold as a result of the medium perfusion. In an embodiment, the bioreactor has a mold into which perfusion medium is pumped under pressure and multiple ports through which the medium exits the mold. |
| FILED | Monday, June 26, 2017 |
| APPL NO | 15/633317 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/28 (20130101) Original (OR) Class A61F 2/3099 (20130101) A61F 2/30942 (20130101) A61F 2002/30957 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 25/14 (20130101) C12M 29/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517745 | Goldfarb et al. |
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| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Michael Goldfarb (Franklin, Tennessee); Huseyin Atakan Varol (Nashville, Tennessee); Kevin Ha (Nashville, Tennessee) |
| ABSTRACT | Systems and methods for controlling a weight bearing member having at least one powered joint are provided. A system includes a velocity reference module for receiving myoelectric control signals from a user during a non-weight bearing mode for the powered joint and generating a velocity reference for the powered joint based on the myoelectric control signals. The system further includes a volitional impedance module for generating a torque control signal for actuating the powered joint based at least on the velocity reference. |
| FILED | Monday, May 08, 2017 |
| APPL NO | 15/589543 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/04888 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/60 (20130101) A61F 2/64 (20130101) A61F 2/72 (20130101) Original (OR) Class A61F 2/6607 (20130101) A61F 5/01 (20130101) A61F 2002/701 (20130101) A61F 2002/704 (20130101) A61F 2002/764 (20130101) A61F 2002/6827 (20130101) A61F 2002/7615 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517755 | D'Ambrosio et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington); Washington University (St. Louis, Missouri); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington); WASHINGTON UNIVERSITY (St. Louis, Missouri); REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Raimondo D'Ambrosio (Seattle, Washington); Jason Fender (Bonney Lake, Washington); Jeffrey Ojemann (Seattle, Washington); John W. Miller (Bellevue, Washington); Matthew Smyth (Frontenac, Missouri); Steven M. Rothman (Clayton, Missouri) |
| ABSTRACT | Passive prosthetic devices for focally cooling a brain and methods for inhibiting seizures are disclosed. The prosthetic devices replace a thermally insulating bone flap with a thermally conductive insert having an inner surface that contacts the relatively warm meninges or brain and an outer surface that contacts the relatively cool scalp. In an embodiment, the prosthesis is unitary; in another, a biocompatible casing is filled with a highly conductive core; in another, a filled polymer block is attached to a plate; and in another, the bone flap is filled with a conductive polymer. In one embodiment, a filled polymer containing elements that exhibit the magnetocaloric effect provide heat transfer that can be enhanced by application of a suitable magnetic field. Focal cooling as low as 1.2° C. has been found effective at inhibiting seizures. |
| FILED | Monday, November 14, 2016 |
| APPL NO | 15/351345 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/10 (20130101) A61F 7/12 (20130101) Original (OR) Class A61F 2007/0002 (20130101) A61F 2007/0096 (20130101) A61F 2007/108 (20130101) A61F 2007/126 (20130101) A61F 2007/0247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517819 | Bellinger et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Andrew Bellinger (Wellesley, Massachusetts); Shiyi Zhang (Shanghai, China PRC); Carlo Giovanni Traverso (Newton, Massachusetts); Robert S. Langer (Newton, Massachusetts); Stacy Mo (Darien, Illinois); Tyler Grant (Brighton, Massachusetts); Mousa Jafari (Waltham, Massachusetts); Dean Liang Glettig (Cambridge, Massachusetts); Angela DiCiccio (San Francisco, California); Lowell L. Wood, Jr. (Bellevue, Washington); Philip A. Eckhoff (Kirkland, Washington) |
| ABSTRACT | Described are gastric residence structures that include an active substance. The gastric residence structures may include one or more arms that include a loadable polymeric component, an elastic polymeric component, and a separate linker component. The linker may connect the one or more arms with the elastic polymeric component. The gastric residence structures may be configured to be folded and physically constrained during administration and may be configured to assume an open retention shape upon removal of a constraint. The change between the folded shape and the open retention shape may be mediated by the elastic polymeric component that undergoes elastic deformation when the residence structure is in the folded shape and recoils when the gastric residence structure assumes the open retention shape. |
| FILED | Friday, February 15, 2019 |
| APPL NO | 16/277516 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/48 (20130101) A61K 9/0053 (20130101) A61K 9/0065 (20130101) Original (OR) Class A61K 31/65 (20130101) A61K 31/357 (20130101) A61K 31/7048 (20130101) A61K 47/10 (20130101) A61K 47/32 (20130101) A61K 47/34 (20130101) A61K 47/40 (20130101) A61K 47/42 (20130101) A61K 47/58 (20170801) A61K 47/6901 (20170801) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/002 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/4277 (20130101) C08G 63/08 (20130101) C08G 83/006 (20130101) C08G 2230/00 (20130101) Compositions of Macromolecular Compounds C08L 33/02 (20130101) C08L 33/08 (20130101) C08L 33/14 (20130101) C08L 2203/02 (20130101) Technologies for Adaptation to Climate Change Y02A 50/411 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517820 | Bellinger et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Tokitae LLC (Bellevue, Washington) |
| INVENTOR(S) | Andrew Bellinger (Wellesley, Massachusetts); Shiyi Zhang (Shanghai, China PRC); Carlo Giovanni Traverso (Newton, Massachusetts); Robert S. Langer (Newton, Massachusetts); Stacy Mo (Darien, Illinois); Tyler Grant (Arlington, Massachusetts); Mousa Jafari (Waltham, Massachusetts); Dean Liang Glettig (Cambridge, Massachusetts); Angela DiCiccio (San Francisco, California); Lowell L. Wood, Jr. (Bellevue, Washington); Philip A. Eckhoff (Kirkland, Washington) |
| ABSTRACT | Described are methods of making a gastric residence structure including an active substance. The methods may include forming one or more arms comprising a loadable polymeric component, wherein the loadable polymeric component includes one or more polymeric materials and at least one active substance. The methods may also include connecting the one or more arms to an elastic polymeric component using a separate linker component. The gastric residence structures may be configured to be folded and physically constrained during administration and may be configured to assume an open retention shape upon removal of a constraint. The change between the folded shape and the open retention shape may be mediated by the elastic polymeric component that undergoes elastic deformation when the residence structure is in the folded shape and recoils when the gastric residence structure assumes the open retention shape. |
| FILED | Tuesday, April 09, 2019 |
| APPL NO | 16/379727 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/48 (20130101) A61K 9/0053 (20130101) A61K 9/0065 (20130101) Original (OR) Class A61K 31/65 (20130101) A61K 31/357 (20130101) A61K 31/7048 (20130101) A61K 47/10 (20130101) A61K 47/32 (20130101) A61K 47/34 (20130101) A61K 47/40 (20130101) A61K 47/42 (20130101) A61K 47/58 (20170801) A61K 47/6901 (20170801) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/002 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/4277 (20130101) C08G 63/08 (20130101) C08G 83/006 (20130101) C08G 2230/00 (20130101) Compositions of Macromolecular Compounds C08L 33/02 (20130101) C08L 33/08 (20130101) C08L 33/14 (20130101) C08L 2203/02 (20130101) Technologies for Adaptation to Climate Change Y02A 50/411 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517822 | Lin et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Wenbin Lin (Chicago, Illinois); Chunbai He (Chicago, Illinois); Demin Liu (Round Lake, Illinois) |
| ABSTRACT | Nanoscale coordination polymer nanoparticles for the co-delivery of multiple therapeutic agents are described. The multiple therapeutic agents can include a combination of different chemotherapeutic agents, a combination of one or more chemotherapeutic agents and one or more nucleic acids, such as small interfering RNA (siRNA) or microRNA, a combination of one or more chemotherapeutic agents and a photosensitizer (i.e., for use in photodynamic therapy), or a plurality of different siRNAs. Pharmaceutical formulations including the nanoparticles, methods of using the nanoparticles to treat cancer, and methods of making the nanoparticles are also described. |
| FILED | Thursday, November 06, 2014 |
| APPL NO | 15/034799 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) Original (OR) Class A61K 31/664 (20130101) A61K 31/713 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517866 | Laberge et al. |
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| FUNDED BY |
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| APPLICANT(S) | Unity Biotechnology, Inc. (Brisbane, California); Buck Institute for Research on Aging (Novato, California); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Unity Biotechnology, Inc. (Brisbane, California); Buck Institute for Research on Aging (Novato, California); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Remi-Martin Laberge (San Francisco, California); James L. Kirkland (Rochester, Minnesota); Tamar Tchkonia (Rochester, Minnesota); Yi Zhu (Rochester, New York); Nathaniel David (Brisbane, California); Alain Philippe Vasserot (Carlsbad, California); Darren J. Baker (Rochester, Minnesota); Bennett G. Childs (Rochester, Minnesota); Jan M. A. van Deursen (Rochester, New York) |
| ABSTRACT | Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders. |
| FILED | Wednesday, May 16, 2018 |
| APPL NO | 15/981696 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0073 (20130101) A61K 31/404 (20130101) A61K 31/428 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/728 (20130101) A61K 31/4178 (20130101) A61K 31/4375 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 47/36 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) A61P 11/00 (20180101) A61P 27/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0081 (20130101) C12N 2501/999 (20130101) C12N 2503/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517877 | Ansari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Aseem Ansari (Madison, Wisconsin); Graham Erwin (Indianapolis, Indiana); Matthew Grieshop (New Berlin, Wisconsin) |
| ABSTRACT | The present technology relates to compositions and methods for modulating expression of genes, which include a target oligonucleotide sequence, such as repeats of a particular oligonucleotide sequence containing 3 to 10 nucleotides. In particular aspects, the present technology relates to agents having a formula A-L-B, wherein -L- is a linker; A- is a Brd4 binding moiety; and -B is a nucleic acid binding moiety, such as a polyamide or complementary oligonucleotide, that specifically binds to the target oligonucleotide sequence. |
| FILED | Wednesday, March 29, 2017 |
| APPL NO | 15/472852 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/785 (20130101) A61K 31/795 (20130101) A61K 31/4164 (20130101) A61K 31/5517 (20130101) Original (OR) Class Heterocyclic Compounds C07D 513/12 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/08 (20130101) Compositions of Macromolecular Compounds C08L 77/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517884 | Desimone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Joseph Desimone (Glen Ellyn, Illinois); Yogen Saunthararajah (Cleveland, Ohio) |
| ABSTRACT | Embodiments of compositions and methods for the treatment of blood disorders and malignancies in a subject are described herein. In one embodiment, a composition for the treatment of a blood disorder or a malignancy in a subject comprises decitabine, tetrahydrouridine, and an excipient. In another embodiment, a method for the treatment of a blood disorder or a malignancy in a subject comprises the oral administration of a composition comprising decitabine and tetrahydrouridine. In some examples, the composition may be administered 1-3 times weekly. |
| FILED | Friday, January 19, 2018 |
| APPL NO | 15/875727 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7068 (20130101) Original (OR) Class A61K 31/7068 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517887 | Kay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Mark A. Kay (Los Altos, California); Anton McCaffrey (Pacifica, California) |
| ABSTRACT | Methods and compositions are provided for modulating, e.g., reducing, coding sequence expression in mammals. In the subject methods, an effective amount of an RNAi agent, e.g., an interfering ribonucleic acid (such as an siRNA or shRNA) or a transcription template thereof, e.g., a DNA encoding an shRNA, is administered to a non-embryonic mammal, e.g., via a hydrodynamic administration protocol. Also provided are RNAi agent pharmaceutical preparations for use in the subject methods. The subject methods and compositions find use in a variety of different applications, including academic and therapeutic applications. |
| FILED | Friday, July 12, 2013 |
| APPL NO | 13/941262 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7105 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 49/0008 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517888 | McKenzie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THOMAS JEFFERSON UNIVERSITY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THOMAS JEFFERSON UNIVERSITY (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Steven E. McKenzie (Springfield, Pennsylvania); Yuhang Zhou (Philadelphia, Pennsylvania); Shaji Abraham (Cherry Hill, New Jersey) |
| ABSTRACT | Disclosed are anti-miR compositions and methods of use of the same for treatment of or reducing the occurrence of thrombosis and thrombosis related diseases and disorders by reducing platelet activation. |
| FILED | Tuesday, December 08, 2015 |
| APPL NO | 15/534410 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7105 (20130101) Original (OR) Class A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/00 (20130101) C12N 15/113 (20130101) C12N 2310/113 (20130101) C12N 2310/3231 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517890 | Shapiro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Bruce A. Shapiro (Gaithersburg, Maryland); Kirill A. Afonin (Charlotte, North Carolina); Mathias D. Viard (Frederick, Maryland) |
| ABSTRACT | The instant invention provides RNA nanocubes, DNA nanocubes and R/DNA chimeric nanocubes comprising one or more functionalities. The multifunctional RNA nanocubes are suitable for therapeutic or diagnostic use in a number of diseases or disorders. |
| FILED | Wednesday, May 06, 2015 |
| APPL NO | 15/309157 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Original (OR) Class A61K 47/50 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/79 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/51 (20130101) C12N 2310/3519 (20130101) C12N 2320/11 (20130101) C12N 2320/51 (20130101) C12N 2320/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517898 | Chute |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | John P. Chute (Sherman Oaks, California) |
| ABSTRACT | In some aspects, the invention relates to populations of hematopoietic cells that are enriched in PTPσ− cells and methods of use thereof. |
| FILED | Friday, November 20, 2015 |
| APPL NO | 15/528355 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 35/51 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 5/0663 (20130101) C12N 5/0665 (20130101) C12N 2501/73 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517942 | Berman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Phillip Berman (Santa Cruz, California); Rachel Doran (Santa Cruz, California); Gabriel Byrne (Santa Cruz, California); Rebecca Dubois (Santa Cruz, California); Javier Morales (Santa Cruz, California); Bin Yu (Santa Cruz, California); Gerardo Perez (Santa Cruz, California); Kathryn Mesa (Santa Cruz, California); David Alexander (Santa Cruz, California) |
| ABSTRACT | Creation of HIV-1 vaccine immunogens based on glycopeptide scaffolds containing sequences from the V1/V2/V3 and C3 domains of HIV-1 gp120 that is able to bind multiple broadly neutralizing antibodies when expressed in mammalian cells that incorporate mannose-5 and mannose-9 glycans. |
| FILED | Monday, August 01, 2016 |
| APPL NO | 15/741981 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/575 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517948 | Ariizumi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Kiyoshi Ariizumi (Dallas, Texas); Ponciano Cruz (Dallas, Texas) |
| ABSTRACT | The present disclosure is directed to antibodies that bind to DC-HIL on the surface of myeloid-derived suppressor cells, and thus antagonize the T cell suppressor function of these cells, as well as their use in diagnosing and treating cancers such as melanoma. |
| FILED | Wednesday, March 09, 2016 |
| APPL NO | 15/556985 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 39/395 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) Peptides C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/2827 (20130101) C07K 2317/76 (20130101) C07K 2319/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6886 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5743 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517955 | Bachovchin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | William W. Bachovchin (Cambridge, Massachusetts); Hung-sen Lai (Andover, Massachusetts); Sarah E. Poplawski (Belmont, Massachusetts) |
| ABSTRACT | Disclosed are proteasome inhibitors, fibroblast activation protein (FAP)-activated prodrugs of proteasome inhibitors, and pharmaceutically acceptable salts of the inhibitors and prodrugs. Also disclosed are related pharmaceutical compositions, and methods of using the inhibitors and prodrugs and compositions thereof, for example, in treating cancer or other cell proliferative diseases. In vitro and in vivo methods of quantifying the expression of FAP in a biopsy sample and a mammal, respectively, are also disclosed. |
| FILED | Friday, April 13, 2018 |
| APPL NO | 15/952648 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 38/00 (20130101) A61K 38/07 (20130101) A61K 45/06 (20130101) A61K 47/54 (20170801) A61K 47/64 (20170801) Original (OR) Class Peptides C07K 5/081 (20130101) C07K 5/0806 (20130101) C07K 5/0808 (20130101) C07K 5/0812 (20130101) C07K 5/0821 (20130101) C07K 5/1016 (20130101) C07K 5/06026 (20130101) C07K 5/06034 (20130101) C07K 5/06078 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517964 | Gambhir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sanjiv S. Gambhir (Portola Valley, California); Zhen Cheng (Mountain View, California); Sri-rajasekhar Kothapalli (Mountain View, California); Hongguang Liu (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Sanjiv S. Gambhir (Portola Valley, California); Zhen Cheng (Mountain View, California); Sri-rajasekhar Kothapalli (Mountain View, California); Hongguang Liu (Palo Alto, California) |
| ABSTRACT | Embodiments of the present disclosure provide for radionuclide probes, methods of using the radionuclide probes, methods of detecting an optical signal from radionuclides, methods of detecting an optical signal from a quantum dot(s) that receives optical energy from a radionuclide(s), system for analyzing optical energy emitted by a radionuclide(s), system for imaging a target within a living subject or a sample, methods of imaging a disease or condition, and the like. |
| FILED | Tuesday, February 28, 2012 |
| APPL NO | 13/406891 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 6/037 (20130101) A61B 6/508 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0013 (20130101) Original (OR) Class A61K 51/00 (20130101) A61K 51/0491 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517987 | Stewart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Russell J. Stewart (Salt Lake City, Utah); Hui Shao (Salt Lake City, Utah) |
| ABSTRACT | Described herein is the synthesis of adhesive complex coacervates and their use thereof. The adhesive complex coacervates are composed of a mixture of one or more polycations and one or more polyanions. The polycations and polyanions in the adhesive complex coacervate are crosslinked with one another by covalent bonds upon curing. The adhesive complex coacervates have several desirable features when compared to conventional bioadhesives, which are effective in water-based applications. The adhesive complex coacervates described herein exhibit good interfacial tension in water when applied to a substrate (i.e., they spread over the interface rather than being beaded up). Additionally, the ability of the complex coacervate to crosslink intermolecularly increases the cohesive strength of the adhesive complex coacervate. The adhesive complex coacervates have numerous biological applications as bioadhesives and drug delivery devices. In particular, the adhesive complex coacervates described herein are particularly useful in underwater applications and situations where water is present such as, for example, physiological conditions. |
| FILED | Monday, March 12, 2018 |
| APPL NO | 15/918423 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2846 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/0015 (20130101) A61L 24/043 (20130101) A61L 24/0073 (20130101) Original (OR) Class A61L 27/26 (20130101) A61L 27/54 (20130101) A61L 2300/62 (20130101) A61L 2300/602 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/00 (20130101) C08F 8/00 (20130101) C08F 8/06 (20130101) C08F 8/06 (20130101) C08F 8/10 (20130101) C08F 8/10 (20130101) C08F 220/54 (20130101) C08F 220/56 (20130101) C08F 230/02 (20130101) C08F 230/02 (20130101) C08F 230/02 (20130101) C08F 230/02 (20130101) C08F 2800/10 (20130101) C08F 2810/20 (20130101) C08F 2810/30 (20130101) Compositions of Macromolecular Compounds C08L 33/26 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 133/26 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 133/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10518107 | Parker |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Kevin Kit Parker (Waltham, Massachusetts) |
| ABSTRACT | Photosensitive cardiac rhythm modulation structures and systems are described. A genetically-engineered tissue comprising a population of pacing cells expressing a photosensitive membrane transport mechanism that is responsive to light of a particular wavelength(s) combined with one or more of a light source, a power generator, and a sensor provides pacemaker and/or defibrillator function to a subject. The systems further provide in vitro model systems for electrophysiological studies. |
| FILED | Friday, April 25, 2014 |
| APPL NO | 14/261693 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0622 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519113 | Dar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| INVENTOR(S) | Arvin C. Dar (New York, New York); Ross L. Cagan (New York, New York); Alex P. Scopton (New York, New York); Masahiro Sonoshita (New York, New York) |
| ABSTRACT | The present invention relates to a compound having the structure of formula (I) or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof, where X, Y, Z, R, R1, R2, R3, R4, R5, and R6 are as described herein. The present invention also relates to compositions containing the compound having the structure of formula (I), and a method of treating cancer in a subject. |
| FILED | Thursday, August 17, 2017 |
| APPL NO | 16/325218 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 213/81 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519114 | Mosberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Henry Mosberg (Ann Arbor, Michigan); Deanna Montgomery (Ann Arbor, Michigan); Aaron Bender (Spring Hill, Tennessee); Anthony Nastase (Ann Arbor, Michigan); Sean Henry (Ann Arbor, Michigan); Aubrie Harland (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are compounds useful for modulating the mu-opioid receptor (“MOR”) and/or delta-opioid receptor (“DOR”), and methods of using these compounds to treat diseases and conditions, such as pain. In particular, disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salt thereof: wherein the substituents are as described. |
| FILED | Friday, September 15, 2017 |
| APPL NO | 15/705497 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 237/04 (20130101) C07C 237/20 (20130101) C07C 2602/08 (20170501) C07C 2602/10 (20170501) Heterocyclic Compounds C07D 215/42 (20130101) Original (OR) Class C07D 215/58 (20130101) C07D 223/16 (20130101) C07D 311/68 (20130101) C07D 335/06 (20130101) C07D 401/06 (20130101) C07D 405/04 (20130101) C07D 405/06 (20130101) C07D 471/04 (20130101) C07D 471/06 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519149 | Fuller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rodin Therapeutics, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Rodin Therapeutics, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathan Oliver Fuller (Arlington, Massachusetts); John A. Lowe, III (Stonington, Connecticut) |
| ABSTRACT | Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g., HDAC2). |
| FILED | Friday, March 23, 2018 |
| APPL NO | 15/934299 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519160 | Van de Bittner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Genevieve Van de Bittner (Stoneham, Massachusetts); Jacob M. Hooker (Belmont, Massachusetts) |
| ABSTRACT | Provided herein are radiolabeled compounds useful for non-invasive imaging techniques. An exemplary radiolabeled compound provided herein is useful as a radiotracer for positron emission tomography. The present application also provides unlabeled compounds useful in methods of treating diseases of the central nervous system or disease of the peripheral nervous system. Methods for preparing radiolabeled compounds, preparing unlabeled compounds, and diagnostic methods using labeled or unlabeled compounds are also provided. |
| FILED | Friday, July 17, 2015 |
| APPL NO | 15/326890 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0459 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) C07B 2200/05 (20130101) Heterocyclic Compounds C07D 473/16 (20130101) C07D 473/34 (20130101) C07D 473/40 (20130101) Original (OR) Class C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519161 | Buynak |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas) |
| INVENTOR(S) | John D. Buynak (Dallas, Texas) |
| ABSTRACT | The present invention includes compositions, methods of making and using novel carbapenem compounds including active agents, compounds, antibacterial agents, pharmaceutically acceptable salts of C1α-C1β di-substituted carbapenem compounds, C5α substituted carbapenem compounds, C6α-C6β di-substituted carbapenem compounds and combinations thereof. |
| FILED | Tuesday, October 29, 2013 |
| APPL NO | 14/066367 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 477/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519198 | Deverman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Benjamin E. Deverman (Pasadena, California); Paul H. Patterson (Altadena, California); Viviana Gradinaru (La Cañada Flintridge, California) |
| ABSTRACT | Provided herein are methods of selective screening. In addition, various targeting proteins and sequences, as well as methods of their use, are also provided. |
| FILED | Monday, December 17, 2018 |
| APPL NO | 16/222549 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/47 (20130101) A61K 38/50 (20130101) A61K 38/1709 (20130101) A61K 38/2093 (20130101) A61K 38/4813 (20130101) A61K 39/3955 (20130101) A61K 48/005 (20130101) A61K 48/0058 (20130101) Peptides C07K 7/06 (20130101) C07K 14/005 (20130101) Original (OR) Class C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/1068 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) C12N 2810/6027 (20130101) Enzymes C12Y 304/14009 (20130101) C12Y 305/01015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519205 | Spudich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | John Lee Spudich (Houston, Texas); Elena G. Govorunova (Houston, Texas); Oleg A. Sineshchekov (Houston, Texas) |
| ABSTRACT | Methods and compositions used to identify and characterize a new class of rhodopsins derived from algae, which are highly sensitive and efficient anion-conducting channelrhodopsins. The rhodopsin domain of these anion-conducting channelrhodopsins have been cloned and expressed in mammalian systems and thus may be used in, among others, optogenetic applications and as therapeutic agents for electrically active cell mediated disorders. |
| FILED | Friday, March 18, 2016 |
| APPL NO | 15/559512 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/0058 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) C12N 15/79 (20130101) C12N 15/82 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519207 | Murphy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Anne Z. Murphy (Atlanta, Georgia); Lori Eidson (Atlanta, Georgia) |
| ABSTRACT | The present disclosure is directed to a method of treating morphine tolerance and/or symptoms associated therewith by administration to a subject in need thereof a DN-TNF polypeptide that inhibits the activity of soluble TNF- but not transmembrane TNF-α. |
| FILED | Monday, June 13, 2016 |
| APPL NO | 15/735672 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/135 (20130101) A61K 38/191 (20130101) A61K 47/60 (20170801) Peptides C07K 14/525 (20130101) Original (OR) Class C07K 2319/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519210 | Debinski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| INVENTOR(S) | Waldemar Debinski (Winston-Salem, North Carolina); Hetal Pandya (Winston-Salem, North Carolina); Denise Gibo (Winston-Salem, North Carolina) |
| ABSTRACT | A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13Rα2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described. |
| FILED | Wednesday, January 30, 2019 |
| APPL NO | 16/262195 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/642 (20170801) Peptides C07K 14/005 (20130101) C07K 14/21 (20130101) C07K 14/34 (20130101) C07K 14/195 (20130101) C07K 14/5437 (20130101) Original (OR) Class C07K 19/00 (20130101) C07K 2319/01 (20130101) C07K 2319/09 (20130101) C07K 2319/74 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/532 (20130101) G01N 33/5008 (20130101) G01N 33/5091 (20130101) G01N 33/6869 (20130101) G01N 2333/025 (20130101) G01N 2333/195 (20130101) G01N 2333/5437 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519222 | Schramm et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human SERVICES (Bethesda, Maryland); The Trustees of Columbia University in the City of New York (New York, New York); Centre for the AIDS Programme of Research in South Africa (Durban, South Africa); University of the Witwatersrand, Johannesburg (Johannesburg, South Africa); National Health Laboratory Service (Sandringham, South Africa) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); CENTRE FOR THE AIDS PROGRAMME OF RESEARCH IN SOUTH AFRICA (Durban, South Africa); UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (Johannesburg, South Africa); NATIONAL HEALTH LABORATORY SERVICE (Sandringham, South Africa) |
| INVENTOR(S) | Chaim Aryeh Schramm (Bronx, New York); Jason Gorman (Washington, District of Columbia); John Mascola (Rockville, Maryland); Lawrence Stewart Shapiro (New York, New York); Lynn Morris (Randburg, South Africa); Nicole Amy Doria-Rose (Kensington, Maryland); Penelope Linda Moore (Modderfontein, South Africa); Peter Dak Pin Kwong (Washington, District of Columbia); Salim Safurdeen Abdool Karim (Durban, South Africa) |
| ABSTRACT | The present invention relates anti-HIV therapies and prophylaxis. Specifically, the invention relates to broadly neutralizing antibodies against HIV-1, nucleic acids encoding these antibodies, vectors comprising the nucleic acids and cells and pharmaceutical compositions Comprising said vectors and/or antibodies. The present invention also relates to use of the antibodies and/or vectors for the treatment and/or prevention of HIV-1 infection in a subject. Furthermore, the invention also relates to a kit containing the antibodies of the invention. |
| FILED | Friday, February 27, 2015 |
| APPL NO | 15/121051 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519412 | Beebe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David Beebe (Monona, Wisconsin); Erwin Berthier (Madison, Wisconsin); Mary Regier (Madison, Wisconsin) |
| ABSTRACT | A stamp and a method for transferring particles to cells of a cell culture. The stamp includes a body having upper and lower surfaces. The lower surface includes a recessed portion. A gel extends along the recessed portion of the lower surface of the body and including the particles patterned therein. The body is configured to move between a first position wherein the gel is isolated from the cells of the cell culture and a second position wherein the particles patterned in the gel communicate with the cells of the cell culture through diffusion. |
| FILED | Friday, June 19, 2015 |
| APPL NO | 14/744765 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 29/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519442 | Glackin et al. |
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| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | Carlotta A. Glackin (Duarte, California); John Rossi (Azusa, California); Jeffrey I. Zink (Los Angeles, California); Fuyuhiko Tamanoi (Los Angeles, California); Cai M. Roberts (Duarte, California); James Finlay (Duarte, California) |
| ABSTRACT | The present invention relates to compositions comprising TWIST signaling inhibitors and optionally one or more anti-cancer agents, and methods of using the compositions for the treatment of cancer. |
| FILED | Friday, February 10, 2017 |
| APPL NO | 15/430372 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6923 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/332 (20130101) C12N 2310/335 (20130101) C12N 2310/351 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519443 | Amendt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Brad A. Amendt (Iowa City, Iowa); Huojun Cao (Iowa City, Iowa) |
| ABSTRACT | The present invention relates to plasmid-based miR inhibitory systems (PMIS), miR inhibitors and methods of use of these systems and inhibitors. |
| FILED | Tuesday, September 08, 2015 |
| APPL NO | 15/508857 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/531 (20130101) C12N 2330/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519444 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jeannie T. Lee (Boston, Massachusetts); Hsueh-Ping Chu (Weymouth, Massachusetts) |
| ABSTRACT | Inhibitory nucleic acids, e.g., antisense oligonucleotides (ASO) against PAR-TERRA RNA or other chromosome-specific TERRA transcripts (i.e., inclusive of chromosome-specific subtelomeric sequences), and methods of use thereof to downregulate expression of escapee genes on the inactive X chromosome, expression from the active X chromosome, subtelomeric autosomal loci (e.g., FSHD locus), or expression of autosomal genes involved in growth control and apoptosis, e.g., in cells and subjects with supernumerary X chromosomes and/or cancer and other human diseases. |
| FILED | Thursday, December 01, 2016 |
| APPL NO | 15/780509 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/111 (20130101) C12N 2310/113 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/341 (20130101) C12N 2310/3231 (20130101) C12N 2310/3521 (20130101) C12N 2310/3533 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519445 | Maguire et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Casey A. Maguire (Arlington, Massachusetts); Florian Eichler (Cambridge, Massachusetts) |
| ABSTRACT | Methods of the invention encompass delivery of nucleic acid sequences encoding ABCD1 for the treatment of X-linked Adrenoleukodystrophy (X-ALD), e.g., for Adrenomyeloneuropathy (AMN). |
| FILED | Tuesday, April 02, 2019 |
| APPL NO | 16/373081 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0004 (20130101) A61K 9/0085 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) A61K 48/0075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2750/14141 (20130101) C12N 2750/14143 (20130101) C12N 2750/14152 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519453 | Smolke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Christina D. Smolke (Menlo Park, California); Catherine Thodey (Mountain View, California); Isis Trenchard (Redwood City, California) |
| ABSTRACT | Methods and engineered yeast cells for generating a benzylisoquinoline alkaloid product are provided herein. A method comprises providing engineered yeast cells and a feedstock to a reactor. In the reactor, the engineered yeast cells are subjected to fermentation by incubating the engineered yeast cells for a time period to produce a solution comprising the BIA product and cellular material. The solution comprises not more than one class of molecule selected from the group of protoberberine, morphinan, isopavine, aporphine, and benzylisoquinoline. Additionally, at least one separation unit is used to separate the BIA product from the cellular material to provide the product stream comprising the BIA product. |
| FILED | Friday, October 19, 2018 |
| APPL NO | 16/165940 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Heterocyclic Compounds C07D 217/18 (20130101) C07D 217/22 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/52 (20130101) Original (OR) Class C12N 15/79 (20130101) C12N 15/81 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 13/22 (20130101) C12P 17/12 (20130101) Enzymes C12Y 114/16002 (20130101) C12Y 401/01028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519470 | Ajikumar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); National University of Singapore (Singapore, Singapore) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); National University of Singapore (Singapore, Singapore) |
| INVENTOR(S) | Parayil K. Ajikumar (Cambridge, Massachusetts); Gregory Stephanopoulos (Winchester, Massachusetts); Heng Phon Too (Singapore, Singapore) |
| ABSTRACT | The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids. |
| FILED | Monday, March 19, 2018 |
| APPL NO | 15/924700 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/007 (20130101) Original (OR) Class C12P 7/42 (20130101) C12P 9/00 (20130101) C12P 15/00 (20130101) C12P 17/02 (20130101) C12P 19/56 (20130101) C12P 23/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 2600/158 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519494 | Hung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Combinati Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | COMBINATI INCORPORATED (Palo Alto, California) |
| INVENTOR(S) | Ju-Sung Hung (Palo Alto, California); Megan Dueck (Brisbane, California); Andrew Zayac (San Leandro, California) |
| ABSTRACT | The present disclose provides methods and systems for amplifying and quantifying nucleic acids and for detecting the presence or absence of a target in a sample. The methods and systems provided herein may utilize a device comprising a plurality of partitions separated from an external environment by a gas-permeable barrier. Certain methods disclosed herein involve subjecting nucleic acid molecules in the plurality of partitions to conditions sufficient to conduct nucleic acid amplification reactions. The nucleic acid molecules may be subjected to controlled heating in the plurality of partitions to generate data indicative of a melting point(s) of the nucleic acid molecules. |
| FILED | Thursday, May 09, 2019 |
| APPL NO | 16/408041 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2200/16 (20130101) B01L 2200/0684 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519499 | Boyanov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Illumina, Inc. (San Diego, California) |
| ASSIGNEE(S) | Illumina, Inc. (San Diego, California) |
| INVENTOR(S) | Boyan Boyanov (San Diego, California); Jeffrey G Mandell (San Diego, California); Kevin L Gunderson (San Diego, California); Jingwei Bai (San Diego, California); Liangliang Qiang (San Diego, California); Bradley Baas (Madison, Wisconsin) |
| ABSTRACT | The disclosure provides detection apparatus having one or more nanopores, methods for making apparatus having one or more nanopore and methods for using apparatus having one or more nanopores. Uses include, but are not limited to detection and sequencing of nucleic acids. |
| FILED | Wednesday, July 29, 2015 |
| APPL NO | 15/522987 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44782 (20130101) G01N 27/44791 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519502 | Falk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Marni J. Falk (Voorhees, New Jersey); Xiaowu Gai (La Canada Flintridge, California); Douglas C. Wallace (Swarthmore, Pennsylvania); Hongbo Xie (Dresher, Pennsylvania) |
| ABSTRACT | Mitochondrial disease genetic diagnostics and methods of use thereof are provided. |
| FILED | Friday, October 31, 2014 |
| APPL NO | 15/032520 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519505 | Ostrer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Harry Ostrer (New York, New York); Alexander Pearlman (New York, New York) |
| ASSIGNEE(S) | Harry Ostrer (New York, New York); Alexander Pearlman (New York, New York) |
| INVENTOR(S) | Harry Ostrer (New York, New York); Alexander Pearlman (New York, New York) |
| ABSTRACT | A method of determining the risk of metastasis of prostate cancer in a human subject who has or had prostate cancer is disclosed herein. The method is based on detecting in a prostate sample from the subject the number of copies per cell of genes and/or genomic regions of a metastatic gene signature set disclosed herein, and determining alternations in the number of copies per cell of the genes and/or genomic regions in the signature set, as compared to the number of copies per cell in non-cancer cells, thereby determining the risk of prostate cancer metastasis. |
| FILED | Friday, April 27, 2012 |
| APPL NO | 14/114057 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519506 | Goel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor Research Institute (Dallas, Texas) |
| ASSIGNEE(S) | Baylor Research Institute (Dallas, Texas) |
| INVENTOR(S) | Ajay Goel (Dallas, Texas); C. Richard Boland (Dallas, Texas); Keun Hur (Dallas, Texas) |
| ABSTRACT | The present invention includes methods and biomarkers for diagnosing or detecting colorectal cancer metastasis in a human subject by comparing the Alu repeat methylation level in the biological sample to an Alu repeat methylation control level from a normal non-cancerous sample from the human subject, wherein a decrease in the Alu repeat methylation level is indicative of colorectal cancer and colorectal cancer metastasis. The invention also includes methods and biomarkers for diagnosing or detecting colorectal cancer (CRC) metastasis in a human subject by determining a level of expression of let-7i, miR-10b, miR-320a, and miR-221 in the sample from the one or more biological samples; and comparing the level of expression of let-7i, miR-10b, miR-320a, and miR-221 in the sample with the level of expression of let-7i, miR-10b, miR-320a, and miR-221 from normal colorectal tissue, wherein high expression of at least on of let-7i or miR-320a is indicative of a good prognosis for the CRC, while the low expression of at least one of miR-10b or miR-221 is indicative of a good prognosis for the CRC or CRC metastasis. |
| FILED | Friday, December 21, 2012 |
| APPL NO | 14/367827 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2525/207 (20130101) C12Q 2600/154 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519518 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human (Rockville, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland) |
| INVENTOR(S) | Jeffrey A. Johnson (Stone Mountain, Georgia); Walid M. Heneine (Atlanta, Georgia) |
| ABSTRACT | Disclosed are compositions including primers and probes, which are capable of interacting with the disclosed nucleic acids, such as the nucleic acids encoding the reverse transcriptase or protease of HIV as disclosed herein. Thus, provided is an oligonucleotide comprising any one of the nucleotide sequences set for in SEQ ID NOS:1-89, and 96-104. Also provided are the oligonucleotides consisting of the nucleotides as set forth in SEQ ID NOS:1-89, and 96-104. Each of the disclosed oligonucleotides is a probe or a primer. Also provided are mixtures of primers and probes and for use in RT-PCR and primary PCR reactions disclosed herein. Provided are methods for the specific detection of several mutations in HIV. Mutations in both the reverse transcriptase and the protease of HIV can be detected using the methods described herein. |
| FILED | Wednesday, September 21, 2016 |
| APPL NO | 15/271269 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Original (OR) Class C12Q 2600/156 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 435/975 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520444 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Po-Jung Huang (College Station, Texas); Gerard L. Coté (College Station, Texas); Mitchell B. Robinson (Willow Park, Texas); Jun Kameoka (College Station, Texas); Haley L. Marks (Brighton, Massachusetts) |
| ABSTRACT | There is a need in the point-of-care diagnostic community for an efficient and portable method for testing blood and other biological fluids that can be easily translated across multiple applications. An aspect of the invention described involves monitoring the optical properties of molecularly-mediated nanoparticle assemblies though an optically transparent and magnetically active microfluidic chip, which has recently emerged as an attractive method for biomarker detection as it is an efficient tool for monitoring the binding events that take place in a sensing assay. In one embodiment, this device is directed towards two-nanoparticle assays that rely on the assembly or disassembly of plasmonic and magnetic nanoparticles in response to a certain analyte. A further embodiment is directed to a spiral microfluidic using inertial forces to filter fluid components by size, connected to a magnetically active channel comprised of a nickel micropad array, optically transparent microchannel, and permanent magnets. |
| FILED | Wednesday, May 09, 2018 |
| APPL NO | 15/975313 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) B01L 2300/088 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 21/658 (20130101) Original (OR) Class G01N 33/553 (20130101) G01N 33/54326 (20130101) G01N 33/54346 (20130101) G01N 33/54366 (20130101) G01N 2001/4088 (20130101) G01N 2021/651 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520472 | Mohapatra et al. |
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| FUNDED BY |
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| APPLICANT(S) | Shyam S. Mohapatra (Lutz, Florida); Subhra Mohapatra (Lutz, Florida); Rasim Oytun Guldiken (Tampa, Florida); Rajesh R. Nair (Tampa, Florida); Tao Wang (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida); TransGenex Nanobiotech, Inc. (Lutz, Florida) |
| INVENTOR(S) | Shyam S. Mohapatra (Lutz, Florida); Subhra Mohapatra (Lutz, Florida); Rasim Oytun Guldiken (Tampa, Florida); Rajesh R. Nair (Tampa, Florida); Tao Wang (Tampa, Florida) |
| ABSTRACT | A novel SH-SAW biosensor capable of non-invasive and touch-free detection of cancer cell viability and growth or proliferation in two-dimensional (2D) and three-dimensional (3D) cell cultures as well as stem cell regeneration as it pertains to cancer cell biology and anti-cancer drug development is presented. The biosensor includes two pairs of resonators including interdigital transducers reflecting fingers to quantify mass loading by the cells in suspension as well as within a tumoroid culture platform. The biosensor can be part of a perfused 3PNS-tumoroid system that is amenable to real-time non-invasive monitoring of the cell proliferation, viability, and multiplexed detection of key physiologic and clinical biomarkers. |
| FILED | Monday, August 21, 2017 |
| APPL NO | 15/682070 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/022 (20130101) Original (OR) Class G01N 29/036 (20130101) G01N 29/222 (20130101) G01N 29/2462 (20130101) G01N 33/48 (20130101) G01N 2291/02466 (20130101) G01N 2291/02475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520499 | Van de Water et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Judy Van de Water (Capay, California); Daniel Braunschweig (Davis, California) |
| ABSTRACT | The present invention provides diagnostic methods for determining the risk of developing an autism spectrum disorder (ASD) in a fetus or child by detecting in a biological sample from the mother antibodies that bind to one or more biomarkers selected from the group consisting of lactate dehydrogenase (LDH), guanine deaminase (GDA), collapsin response mediator protein 1 (CRMP1), stress-induced phosphoprotein 1 (STIP1), alpha subunit of the barbed-end actin binding protein Cap Z (CAPZA2), Y Box Binding Protein 1 (YBX1), eukaryotic translation and elongation factor 1A1 (EEF1A1), microtubule-associated protein Tau (MAPT), dihydropyrimidinase-like protein 2 (DPYSL2), dynamin 1-like protein (DNM1L), radixin (RDX), moesin (MSN), and ezrin (EZR). The invention further provides methods of preventing or reducing the risk of a fetus or child developing an ASD by administering to the mother an agent that blocks the binding of maternal antibodies to the one or more fetal biomarkers listed above or by removing from the mother antibodies that bind to the one or more fetal biomarkers. |
| FILED | Wednesday, November 16, 2016 |
| APPL NO | 15/353037 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/6896 (20130101) G01N 33/54313 (20130101) Original (OR) Class G01N 2800/28 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520509 | Xian et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
| INVENTOR(S) | Ming Xian (Pullman, Washington); Wei Chen (Pullman, Washington) |
| ABSTRACT | Reactive sulfur species have been recognized as an important regulator in redox biology, wherein the reactive sulfur species have been shown to be active in tumor suppressors, ion channels, and transcription factors. The disclosed invention is a novel composition of matter that allows for the detection of H2S and H2Sn species in living cells. These novel compositions represent significant progress in the field of chemical, H2S and H2Sn probes as they have both been successfully applied in the visualization sulfur species in living systems. |
| FILED | Thursday, September 14, 2017 |
| APPL NO | 15/704101 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 311/86 (20130101) C07D 323/00 (20130101) C07D 493/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520516 | Ring et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Aaron Michael Ring (New Haven, Connecticut); Aashish Manglik (Menlo Park, California); Andrew Kruse (Roslindale, Massachusetts); Brian K. Kobilka (Palo Alto, California) |
| ABSTRACT | Provided herein are several methods for selecting agents that bind to transmembrane receptors in a conformationally-selective way. In some embodiments, the method may comprise producing: a transmembrane receptor in an active conformation; and said transmembrane receptor in an inactive conformation and using cell sorting to select, from a population of cells comprising a library of cell surface-tethered extracellular capture agents, cells that are specifically bound to either the transmembrane receptor in its active conformation or the transmembrane receptor in its inactive conformation, but not both. In other embodiments, the method may comprise: contacting a GPCR with a population of cells that comprise a library of surface-tethered extracellular proteins; labeling the cell population with a conformationally-specific binding agent, e.g., a G-protein or mimetic thereof; and using cell sorting to select from the cell population cells that bind to the agent. |
| FILED | Friday, December 15, 2017 |
| APPL NO | 15/844319 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/705 (20130101) C07K 14/70571 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) Original (OR) Class G01N 33/566 (20130101) G01N 33/6842 (20130101) G01N 2333/726 (20130101) G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520517 | Everson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Gregory Thomas Everson (Englewood, Colorado); Steve Mark Helmke (Denver, Colorado) |
| ABSTRACT | A Disease Severity Index (DSI) is provided for assessment of chronic liver disease in a patient using non-invasive liver function test results. A DSI was derived from non-invasive liver function test results based on hepatic blood flow. The DSI is used in methods for prediction of clinical outcomes, prediction of response to antiviral treatment, and assessment of progression of chronic liver diseases. Non-invasive methods to diagnose three distinct categories of patients with Primary Sclerosing Cholangitis (PSC) are provided. The methods can be used to diagnose PSC patients as Slow Progressors, Moderate Progressors and Rapid Progressors. |
| FILED | Wednesday, August 09, 2017 |
| APPL NO | 15/673191 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 2800/085 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520573 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
| INVENTOR(S) | Feiyu Chen (Stanford, California); Tao Zhang (Houston, Texas); Joseph Y. Cheng (Stanford, California); Valentina Taviani (Menlo Park, California); Brian Hargreaves (Stanford, California); John Pauly (Stanford, California); Shreyas Vasanawala (Stanford, California) |
| ABSTRACT | A method for performing wave-encoded magnetic resonance imaging of an object is provided. The method includes applying one or more wave-encoded magnetic gradients to the object, and acquiring MR signals from the object. The method further includes calibrating a wave point-spread function, and reconstructing an image from the MR signals based at least in part on the calibrated wave point-spread function. Calibration of the wave point-spread function is based at least in part on one or more intermediate images generated from the MR signals. |
| FILED | Friday, April 07, 2017 |
| APPL NO | 15/481893 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4822 (20130101) G01R 33/5611 (20130101) Original (OR) Class G01R 33/56509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520575 | Behzadnezhad et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Bahareh Behzadnezhad (Madison, Wisconsin); Nader Behdad (Oregon, Wisconsin); Alan B. McMillan (Madison, Wisconsin) |
| ABSTRACT | A system and method for an electron paramagnetic resonance imaging (EPRI) system includes a magnet configured to apply a static magnetic field to a subject to be imaged and a gradient coil configured to apply a magnetic field gradient to the static magnetic field. The system also includes a parallel plate waveguide (PPWG) configured to use a traveling wave to generate a radio frequency (RF) magnetic field over a volume of interest (VOI) in the subject to elicit EPRI data from the VOI and a processor configured to reconstruct the EPRI data into an image of the VOI. |
| FILED | Friday, May 26, 2017 |
| APPL NO | 15/606811 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/38 (20130101) G01R 33/60 (20130101) Original (OR) Class G01R 33/3607 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520714 | Shroff et al. |
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| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Hari Shroff (Bethesda, Maryland); Justin Taraska (Bethesda, Maryland); John Giannini (Bethesda, Maryland); Yicong Wu (Bethesda, Maryland); Abhishek Kumar (Bethesda, Maryland); Min Guo (Bethesda, Maryland) |
| ABSTRACT | Embodiments related to systems and methods for instant structured microscopy where total internal reflection fluorescence techniques are used to improve optical sectioning and signal-to-noise ratio of structured illumination microscopy are disclosed. |
| FILED | Wednesday, August 23, 2017 |
| APPL NO | 16/326757 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/648 (20130101) G01N 21/6458 (20130101) G01N 2021/6463 (20130101) G01N 2201/105 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) Original (OR) Class G02B 21/0032 (20130101) G02B 21/36 (20130101) G02B 21/0044 (20130101) G02B 21/0048 (20130101) G02B 21/0076 (20130101) G02B 27/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10521657 | Humphrey |
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| FUNDED BY |
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| APPLICANT(S) | Li-Cor, Inc. (Lincoln, Nebraska) |
| ASSIGNEE(S) | LI-COR, Inc. (Lincoln, Nebraska) |
| INVENTOR(S) | Patrick G. Humphrey (Lincoln, Nebraska) |
| ABSTRACT | Systems and methods for detecting, decoupling and quantifying unresolved signals in trace signal data in the presence of noise with no prior knowledge of the signal characteristics (e.g., signal peak location, intensity and width) of the unresolved signals. The systems and methods are useful for analyzing any trace data signals having one or multiple constituent signals, including overlapping constituent signals, and particularly useful for analyzing data signals which often contain an unknown number of constituent signals with varying signal characteristics, such as peak location, peak intensity and peak width, and varying resolutions and varying amounts of asymmetry. A general signal model function is assumed for each unknown, constituent signal in the trace signal data. |
| FILED | Friday, November 02, 2018 |
| APPL NO | 16/179705 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 13/00 (20130101) G01R 23/16 (20130101) Electric Digital Data Processing G06F 11/3466 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0053 (20130101) Original (OR) Class G06K 9/00503 (20130101) Image Data Processing or Generation, in General G06T 2207/20182 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 21/0272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE47786 | Rossignol et al. |
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| FUNDED BY |
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| APPLICANT(S) | Romark Laboratories, L.C. (Tampa, Florida) |
| ASSIGNEE(S) | Romark Laboratories L.C. (Tampa, Florida) |
| INVENTOR(S) | Jean-Francois Rossignol (St. Petersburg, Florida); J. Edward Semple (Tampa, Florida) |
| ABSTRACT | A new class of haloalkyl heteroaryl benzamides is described. These compounds show strong activity against hepatitis viruses. |
| FILED | Monday, January 08, 2018 |
| APPL NO | 15/864411 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/427 (20130101) A61K 31/433 (20130101) A61K 31/454 (20130101) A61K 31/497 (20130101) A61K 31/506 (20130101) A61K 31/4196 (20130101) A61K 31/4245 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 231/40 (20130101) C07D 231/44 (20130101) C07D 233/88 (20130101) C07D 233/90 (20130101) C07D 249/14 (20130101) C07D 261/14 (20130101) C07D 263/48 (20130101) C07D 271/07 (20130101) C07D 271/113 (20130101) C07D 275/03 (20130101) C07D 277/46 (20130101) C07D 277/56 (20130101) C07D 285/08 (20130101) C07D 285/135 (20130101) C07D 401/12 (20130101) C07D 403/06 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 409/06 (20130101) C07D 413/12 (20130101) C07D 417/06 (20130101) C07D 417/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10517755 | D'Ambrosio et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington); Washington University (St. Louis, Missouri); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington); WASHINGTON UNIVERSITY (St. Louis, Missouri); REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Raimondo D'Ambrosio (Seattle, Washington); Jason Fender (Bonney Lake, Washington); Jeffrey Ojemann (Seattle, Washington); John W. Miller (Bellevue, Washington); Matthew Smyth (Frontenac, Missouri); Steven M. Rothman (Clayton, Missouri) |
| ABSTRACT | Passive prosthetic devices for focally cooling a brain and methods for inhibiting seizures are disclosed. The prosthetic devices replace a thermally insulating bone flap with a thermally conductive insert having an inner surface that contacts the relatively warm meninges or brain and an outer surface that contacts the relatively cool scalp. In an embodiment, the prosthesis is unitary; in another, a biocompatible casing is filled with a highly conductive core; in another, a filled polymer block is attached to a plate; and in another, the bone flap is filled with a conductive polymer. In one embodiment, a filled polymer containing elements that exhibit the magnetocaloric effect provide heat transfer that can be enhanced by application of a suitable magnetic field. Focal cooling as low as 1.2° C. has been found effective at inhibiting seizures. |
| FILED | Monday, November 14, 2016 |
| APPL NO | 15/351345 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/10 (20130101) A61F 7/12 (20130101) Original (OR) Class A61F 2007/0002 (20130101) A61F 2007/0096 (20130101) A61F 2007/108 (20130101) A61F 2007/126 (20130101) A61F 2007/0247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517824 | DeSimone et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Belmont, Massachusetts); Benjamin W. Maynor (Durham, North Carolina); Larken E. Euliss (Agoura Hills, California); Ginger Denison Rothrock (Durham, North Carolina); Ansley E. Dennis (Augusta, Georgia); Edward T. Samulski (Chapel Hill, North Carolina); R. Jude Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/846827 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) Original (OR) Class A61K 9/0097 (20130101) A61K 9/5138 (20130101) A61K 9/5153 (20130101) A61K 9/5192 (20130101) A61K 47/34 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 99/0085 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0004 (20130101) H01L 51/0021 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/3154 (20150401) Y10T 428/24273 (20150115) Y10T 428/24479 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517827 | Eber et al. |
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| FUNDED BY |
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| APPLICANT(S) | CureVac AG (Tübingen, Germany) |
| ASSIGNEE(S) | CureVac AG (Tübingen, Germany) |
| INVENTOR(S) | Fabian Johannes Eber (Stuttgart, Germany); Benyamin Yazdan Panah (Tübingen, Germany); Stefanie Sewig (Tübingen, Germany); Thomas Ketterer (Gomaringen, Germany); Thorsten Mutzke (Reutlingen, Germany); Tilmann Roos (Kusterdingen, Germany); Michael Sonntag (Tübingen, Germany); Michael Wiggenhorn (München, Germany); Katharina Kolland (Augsburg, Germany) |
| ABSTRACT | The present invention is directed to a storage-stable formulation of long-chain RNA. In particular, the invention concerns a dry powder composition comprising a long-chain RNA molecule. The present invention is furthermore directed to methods for preparing a dry powder composition comprising a long-chain RNA molecule by spray-drying. The invention further concerns the use of such a dry powder composition comprising a long-chain RNA molecule in the preparation of pharmaceutical compositions and vaccines, to a method of treating or preventing a disorder or a disease, to first and second medical uses of such a dry powder composition comprising a long-chain RNA molecule and to kits, particularly to kits of parts, comprising such a dry powder composition comprising a long-chain RNA molecule. |
| FILED | Friday, May 20, 2016 |
| APPL NO | 15/575284 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) Original (OR) Class A61K 9/1682 (20130101) A61K 39/145 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) A61K 48/0091 (20130101) A61K 2039/53 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) A61P 31/04 (20180101) A61P 31/12 (20180101) A61P 33/02 (20180101) A61P 35/00 (20180101) A61P 37/06 (20180101) A61P 37/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517924 | Thaxton et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | C. Shad Thaxton (Chicago, Illinois); Linda Foit (Chicago, Illinois) |
| ABSTRACT | The invention in aspects relates to methods of treating sepsis using HDL-NP. The methods include the use of nanoparticles having a core and a lipid based shell with optimal lipids therein. |
| FILED | Tuesday, November 24, 2015 |
| APPL NO | 15/529214 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/127 (20130101) A61K 9/5115 (20130101) A61K 9/5184 (20130101) A61K 31/685 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 47/6917 (20170801) A61K 2300/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517990 | Olsen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Bradley D. Olsen (Arlington, Massachusetts); Matthew J. Glassman (Yorba Linda, California); Reginald K. Avery (Bel Air, Maryland) |
| ABSTRACT | Elastin-like polypeptides (ELPs) form hydrogels upon heating. The polypeptides can comprise the generic sequence (XPAVG)n (SEQ ID NO: 4), wherein independently for each occurrence X can be any one of a number of different natural or unnatural amino acids, and n is chosen to determine the size of the protein. Hydrogels comprising the polypeptides have mechanical properties, including elastic modulus and fracture toughness, required for load-bearing applications. |
| FILED | Wednesday, December 02, 2015 |
| APPL NO | 14/956998 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/64 (20130101) A61K 2800/91 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/008 (20130101) Original (OR) Class A61L 26/0047 (20130101) A61L 2300/252 (20130101) A61L 2430/02 (20130101) A61L 2430/06 (20130101) A61L 2430/34 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 19/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10518331 | Mirkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Matthew R. Jones (LaMesa, California); Matthew N. O'Brien (Plymouth, Minnesota) |
| ABSTRACT | Methods of synthesizing various metal nanoparticle structures having high uniformity, using iterative reduction and oxidation conditions, is provided herein. |
| FILED | Monday, July 13, 2015 |
| APPL NO | 15/324283 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0048 (20130101) B22F 9/24 (20130101) Original (OR) Class B22F 2001/0033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10518879 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Lei Zhang (Torrance, California); Deepak Khosla (Camarillo, California); Kyungnam Kim (Oak Park, California); Jiejun Xu (Chino, California); Changsoo S. Jeong (Rancho Palos, California) |
| ABSTRACT | Described is a system for trajectory estimation of a mobile platform, such as a UAV. In operation, the system generates an initial trajectory estimate for the mobile platform which is stored in a trajectory buffer as a buffered trajectory. Images captured at a location are compared with a location recognition database to generate a location label for a current location to designate the current location as a new location or a revisited location. If the location is a revisited location, the system determines if trajectory correction is required. If so, the buffered trajectory is corrected to generate a corrected trajectory as the drift-free trajectory. Finally, the drift-free trajectory can be used in a variety of applications. For example, the drift-free trajectory can be used to cause the mobile platform to traverse a path that coincides with the drift-free trajectory. |
| FILED | Friday, October 07, 2016 |
| APPL NO | 15/288622 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Original (OR) Class B64C 2201/141 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 1/0246 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00664 (20130101) G06K 9/00791 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 2207/30241 (20130101) Traffic Control Systems G08G 5/0069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10518910 | Romano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Marcello Romano (Monterey, California); Paul Oppenheimer (Pacific Grove, California) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Marcello Romano (Monterey, California); Paul Oppenheimer (Pacific Grove, California) |
| ABSTRACT | An agile attitude control system (AACS) that is a three axis attitude control device for small spacecraft based on miniature single gimbal control moment gyroscopes (SGCMGs) actuators. The AACS enables agile attitude slewing and accurate pointing/tracking for spacecraft made of multiple CubeSat units, or, more generally, for nanosatellites. |
| FILED | Friday, February 26, 2010 |
| APPL NO | 12/460923 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/286 (20130101) Original (OR) Class Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519075 | Terry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Brandon C Terry (Lafayette, Indiana); Steven F Son (West Lafayette, Indiana); Ibrahim E Gunduz (Lincoln, Nebraska) |
| ABSTRACT | Solid-fuel rocket propellants comprising an oxidizer, an oxophilic metal-halophilic metal formulation, and a binder are described herein. Further described are processes for preparing such propellants and methods of reducing hydrogen chloride production via the combustion of such propellants. Non-limiting examples of such formulations include aluminum-lithium alloys. |
| FILED | Thursday, November 16, 2017 |
| APPL NO | 15/814871 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 23/02 (20130101) C06B 29/22 (20130101) C06B 33/06 (20130101) Original (OR) Class C06B 45/10 (20130101) C06B 45/18 (20130101) C06B 45/105 (20130101) Compositions of Macromolecular Compounds C08L 1/18 (20130101) C08L 33/20 (20130101) C08L 47/00 (20130101) C08L 75/04 (20130101) Alloys C22C 21/00 (20130101) Jet-propulsion Plants F02K 9/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519076 | Buckner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steven Wayne Buckner (St. Louis, Missouri); Paul Jelliss (St. Louis, Missouri); Stephen Chung (Florissant, Missouri); Jacob M. Laktas (St. Louis, Missouri); Gregory J. Place (St. Louis, Missouri) |
| ASSIGNEE(S) | Saint Louis University (Saint Louis, Missouri) |
| INVENTOR(S) | Steven Wayne Buckner (St. Louis, Missouri); Paul Jelliss (St. Louis, Missouri); Stephen Chung (Florissant, Missouri); Jacob M. Laktas (St. Louis, Missouri); Gregory J. Place (St. Louis, Missouri) |
| ABSTRACT | The present invention generally concerns isolated nanoparticles via the decomposition of a ternary metal hydride. More specifically, the present invention harnesses increased energy densities from two distinct nanoparticles isolated by a precise decomposition of LiAlH4. The singular material is air stable and is a nanocomposite of Li3AlH6 nanoparticles, elemental Al nanoparticles, an amount of Ti metal, and a nanoscale organic layer, which we call nMx. The nanocomposite protects and preserves the high energy densities of the core metals isolated from the controlled reaction and makes the nanoparticles safe to handle in air. The final composite is devoid of byproducts or phase transitions that will decrease the energy output of the nanocomposite. The method of the present invention creates a narrow distribution of nanoparticles that have unique burning characteristics useful for many applications. |
| FILED | Wednesday, December 27, 2017 |
| APPL NO | 15/932062 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/0078 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 45/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
10519265 — Polymeric materials having active cross-linkers, methods for making them, and use thereof
| US 10519265 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| INVENTOR(S) | Ye Zhang (Waltham, Massachusetts); Bing Xu (Newton, Massachusetts) |
| ABSTRACT | The present technology relates to a polymeric material including a plurality of polymer subunits and an active cross-linker, wherein the active cross-linker is covalently linked to the plurality of polymer subunits. The active cross-linker offers a key building block for constructing novel molecular architecture in chemomechanical soft materials and illustrates a new approach to tailor material properties. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 15/923755 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0053 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/54 (20130101) Original (OR) Class C08F 226/02 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/20 (20130101) C08K 5/0025 (20130101) C08K 5/0091 (20130101) Compositions of Macromolecular Compounds C08L 33/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519324 | Mount et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Clemson University Research Foundation (Clemson, South Carolina) |
| ASSIGNEE(S) | Clemson University Research Foundation (Clemson, South Carolina) |
| INVENTOR(S) | Andrew S. Mount (Mountain Rest, South Carolina); Bin San Chan (Hong Kong, California); Mary Beth Johnstone (Clemson, South Carolina) |
| ABSTRACT | Materials and methods for prevention of biofouling are described that incorporate the presence of a conotoxin peptide on a surface. The conotoxin peptide is either directly or indirectly adhered to the surface and interferes with the ability of biofouling organisms to settle on the surface. |
| FILED | Thursday, May 19, 2016 |
| APPL NO | 15/576522 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 2303/20 (20130101) Peptides C07K 7/08 (20130101) C07K 14/43504 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1625 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519410 | Hinojosa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EMULATE, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Emulate, Inc (Boston, Massachusetts) |
| INVENTOR(S) | Christopher David Hinojosa (Malden, Massachusetts); Guy Robert Thompson, II (Watertown, Massachusetts); Joshua Gomes (Cambridge, Massachusetts); Jacob Freake (Somerville, Massachusetts); Doug Sabin (Marblehead, Massachusetts) |
| ABSTRACT | A perfusion manifold assembly is described that allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate. A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body. |
| FILED | Monday, December 17, 2018 |
| APPL NO | 16/221681 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/021 (20130101) A01N 1/0247 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502738 (20130101) B01L 9/527 (20130101) B01L 2200/12 (20130101) B01L 2200/025 (20130101) B01L 2200/027 (20130101) B01L 2300/14 (20130101) B01L 2300/123 (20130101) B01L 2300/161 (20130101) B01L 2300/165 (20130101) B01L 2300/0681 (20130101) B01L 2300/0887 (20130101) B01L 2400/06 (20130101) B01L 2400/0481 (20130101) B01L 2400/0487 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 23/38 (20130101) C12M 23/40 (20130101) C12M 23/42 (20130101) C12M 29/10 (20130101) C12M 35/04 (20130101) C12M 41/40 (20130101) C12M 41/48 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) C12N 2521/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519529 | Wright et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | QuesTek Innovations LLC (Evanston, Illinois) |
| ASSIGNEE(S) | QUESTEK INNOVATIONS LLC (Evanston, Illinois) |
| INVENTOR(S) | James A. Wright (Los Gatos, California); Weiming Huang (State College, Pennsylvania); Abhijeet Misra (Mountain View, California); Jeremy Hoishun Li (Sunnyvale, California); Jiadong Gong (Evanston, Illinois); Dana J. Frankel (Chicago, Illinois) |
| ABSTRACT | An alloy includes, in weight percentage, about 20.0% to about 25.0% chromium, 0% to about 5.0% molybdenum, about 3.0% to about 15.0% cobalt, about 1.5% to about 6.0% niobium, about 1.0% to about 3.0% tantalum, about 1.0% to about 5.0% tungsten, 0% to about 1.0% aluminum, 0% to about 0.05% carbon, 0% to about 0.01% titanium, and the balance nickel and incidental elements and impurities, wherein the alloy includes L12 and D022 precipitates in a compact morphology. |
| FILED | Thursday, November 20, 2014 |
| APPL NO | 14/548488 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 1/023 (20130101) C22C 19/055 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/10 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 21/087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519537 | Hostutler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David Hostutler (Albuquerque, New Mexico); Matthew Bigelow (Albuquerque, New Mexico); Rudolph N. Kohn, Jr. (Rio Rancho, New Mexico); Spencer Olson (Tijeras, New Mexico); Matthew Squires (Kirtland AFB, New Mexico); Daniel R. Blakley (Kaysville, Utah); Eric Imhof (Albuquerque, New Mexico); Brian Kasch (Albuquerque, New Mexico); Mary Spanjers (Springboro, Ohio) |
| ASSIGNEE(S) | UTAH STATE UNIVERSITY RESEARCH FOUNDATION (Logan, Utah) |
| INVENTOR(S) | David Hostutler (Albuquerque, New Mexico); Matthew Bigelow (Albuquerque, New Mexico); Rudolph N. Kohn, Jr. (Rio Rancho, New Mexico); Spencer Olson (Tijeras, New Mexico); Matthew Squires (Kirtland AFB, New Mexico); Daniel R. Blakley (Kaysville, Utah); Eric Imhof (Albuquerque, New Mexico); Brian Kasch (Albuquerque, New Mexico); Mary Spanjers (Springboro, Ohio) |
| ABSTRACT | An alkali-metal dispenser to dispense highly pure rubidium in a high-vacuum environment while not negatively impacting the high-vacuum pressure level. The alkali-metal dispenser is operable in various vapor-deposition applications or to provide a highly pure elemental-alkali metal in cold-atom magneto-optical traps. |
| FILED | Wednesday, January 10, 2018 |
| APPL NO | 15/867308 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/14 (20130101) Original (OR) Class C23C 14/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519617 | Stephens et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Isaac J Stephens (Vicksburg, Mississippi); Bryant A Robbins (Denver, Colorado) |
| ABSTRACT | In certain embodiments, a sand-boil filter includes a hollow, conical, water-porous structure made of a mesh material having spaced mesh holes. The filter is inserted narrow-end down into a sand boil to allow water to flow from the ground through the mesh material and out the top of the sand boil, while blocking solid matter larger than the mesh holes from passing through the mesh material. In some implementations, the filter is filled with gravel that holds the filter in place while allowing water to flow out of the sand boil. Such filters prevent sand boils from growing while relieving the underground hydrostatic pressure that created the sand boil in the first place and inhibiting subterranean erosion that can cause failure of a nearby levee. The conical shape provides relatively large surface area that inhibits clogging and allows each filter to be used for a range of different sand-boil sizes. |
| FILED | Friday, March 02, 2018 |
| APPL NO | 15/910732 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 29/11 (20130101) B01D 29/15 (20130101) B01D 35/02 (20130101) B01D 2201/02 (20130101) B01D 2201/0461 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/004 (20130101) C02F 2103/06 (20130101) Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 3/00 (20130101) Original (OR) Class E02D 3/10 (20130101) E02D 29/00 (20130101) E02D 2200/1692 (20130101) E02D 2300/0075 (20130101) E02D 2600/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519781 | Spangler |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Brandon W. Spangler (Vernon, Connecticut) |
| ABSTRACT | Airfoils having hollow bodies defining first and second airfoil cavities and having inner and outer diameter ends, a first airfoil platform at one end of the hollow body having a gaspath surface and a non-gaspath surface, wherein the hollow body extends from the gaspath surface. A first cavity opening is formed in the non-gaspath surface of the platform to fluidly connect to the first airfoil cavity and a second cavity opening in the platform is fluidly connected to the second airfoil cavity. A first turn cap is fixedly attached to the first airfoil platform on the non-gaspath surface covering the first and second cavity openings of the first airfoil platform and defines a first turning cavity such that the first cavity opening in the first airfoil platform is fluidly connected to the second cavity opening in the first airfoil platform by the first turning cavity. |
| FILED | Thursday, January 12, 2017 |
| APPL NO | 15/404252 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) Original (OR) Class F01D 9/041 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/237 (20130101) F05D 2260/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519794 | Corsmeier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Donald Michael Corsmeier (West Chester, Ohio); Donald Scott Yeager (Loveland, Ohio) |
| ABSTRACT | The present disclosure is directed to a sealing system for a turbine engine including an engine component, the engine component defining an oblique sealing surface defining an annular shape. The oblique sealing surface defines an oblique angle with a centerline of the engine component. The sealing system includes a seal housing and a seal ring. The seal housing is annular and includes a groove that is defined by a first sidewall, a second sidewall, and an end wall connecting the first sidewall and the second sidewall. The seal ring is positioned at least partially within the groove in the seal housing. The seal ring defines a seal contact surface for forming a seal with the oblique sealing surface of the engine component. |
| FILED | Tuesday, July 12, 2016 |
| APPL NO | 15/207596 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/023 (20130101) F01D 11/003 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/35 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 2900/00012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519796 | Grover |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut); Eric A. Grover (Tolland, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Eric A. Grover (Tolland, Connecticut) |
| ABSTRACT | The present disclosure relates generally to a variable area turbine vane row assembly. In an embodiment, the variable area turbine vane row assembly includes rotatable vanes that are circumferentially biased and/or axially biased with respect to adjacent fixed vanes. In another embodiment, the variable area turbine vane row assembly includes multiple rotatable vanes positioned between adjacent fixed vanes, which may optionally be circumferentially biased and/or axially biased with respect to each other as well as to the adjacent fixed vanes. |
| FILED | Tuesday, September 16, 2014 |
| APPL NO | 15/022227 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 17/162 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/123 (20130101) F05D 2240/124 (20130101) F05D 2250/73 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519863 | Roach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | James T. Roach (Vernon, Connecticut); Darin S. Lussier (Guilford, Connecticut) |
| ABSTRACT | The present disclosure relates generally to a turbine engine case assembly, the turbine engine case assembly including a fan case including an outer frame encircling an axis, the outer frame including an outer frame exterior surface and an outer frame interior surface, at least two mounts disposed on the outer frame exterior surface, wherein the at least two mounts are circumferentially spaced along the outer frame exterior surface, and a compliant attachment device operably coupled to the at least two mounts. |
| FILED | Friday, October 02, 2015 |
| APPL NO | 14/874049 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/26 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 21/045 (20130101) F01D 25/28 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/20 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/90 (20130101) F05D 2260/311 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/44 (20130101) Y02T 50/671 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519926 | Filardo |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pliant Energy Systems LLC (Brooklyn, New York) |
| ASSIGNEE(S) | Pliant Energy Systems LLC (Brooklyn, New York) |
| INVENTOR(S) | Benjamin Pietro Filardo (New York, New York) |
| ABSTRACT | The TRAVELING WAVE PROPELLER, PUMP AND GENERATOR APPARATUSES, METHODS AND SYSTEMS include force or forces applied to an arc-like flexible sheet-like material to create a deformed crenated strip fin with strained-deformations. The strained-deformations take on a sinusoid-like form that express the internal energy state of the flexible sheet-like material after it has been configured into a crenated strip fin. After being incorporated into a mechanism with couplings that prevent the crenated strip fin from returning to its un-strained state, the strained-deformations persist. Actuators may be used to sequentially rotate vertebrae attached to the fins causing the travel of sinusoid-like deformations along the fins. In a fluid medium, the traveling waves of sinusoidal deformations may exert force on the fluid causing the fluid to move and/or creating thrust. Arched blades affixed to the fins facilitate propulsion on hard surfaces such as ice. |
| FILED | Monday, October 22, 2018 |
| APPL NO | 16/167293 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Marine Propulsion or Steering B63H 1/37 (20130101) Machines or Engines for Liquids F03B 13/10 (20130101) F03B 13/188 (20130101) F03B 17/06 (20130101) Original (OR) Class Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2200/261 (20130101) F05B 2220/706 (20130101) F05B 2240/40 (20130101) F05B 2240/92 (20130101) F05B 2240/97 (20130101) F05B 2240/311 (20130101) Dynamo-electric Machines H02K 7/1823 (20130101) H02K 11/21 (20160101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519951 | Cavil |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Windsor Locks, Connecticut) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Windsor Locks, Connecticut) |
| INVENTOR(S) | Luke Cavil (Rockford, Illinois) |
| ABSTRACT | A seal tube assembly of a pump system is provided. The seal tube assembly includes a single seal tube having a first axial end sealably coupled to a first vane pump and a second axial end sealably coupled to a second vane pump. The single seal tube includes transverse contact surfaces at the first axial end and transverse contact surfaces at the second axial end. The single seal tube is formed to define a first seal tube cavity at the first axial end and a second seal tube cavity at the second axial end. |
| FILED | Tuesday, January 03, 2017 |
| APPL NO | 15/397397 |
| ART UNIT | 3748 — Electrical Circuits and Systems |
| CURRENT CPC | Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps F04C 2/34 (20130101) F04C 11/001 (20130101) F04C 15/0023 (20130101) Original (OR) Class F04C 2240/30 (20130101) Non-positive-displacement Pumps F04D 13/12 (20130101) F04D 29/106 (20130101) Pistons; Cylinders; Sealings F16J 15/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520035 | Duffy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Kevin Duffy (Hartford, Connecticut); Anthony Spagnoletti (Newington, Connecticut) |
| ABSTRACT | A bearing compartment assembly includes a bearing compartment with a bearing and a plenum, a buffer system that supplies pressure to an exterior of the bearing compartment, and a reactive volume vessel connected to the bearing compartment. The reactive volume vessel has a displaceable member that is movable between two positions, one of which adds additional volume to the bearing compartment. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/343486 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/162 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 33/766 (20130101) Original (OR) Class F16C 35/04 (20130101) F16C 2360/23 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520042 | Swift et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Joseph A. Swift (Indianapolis, Indiana); Kyle A. Hassler (Pittsboro, Indiana); Thaddeus Hendricks (Indianapolis, Indiana) |
| ABSTRACT | A clutch assembly may comprise a plurality of clutch discs and a housing configured to receive the plurality of clutch discs. The housing may include an outer wall and an inner wall defining a channel therebetween. The outer wall may have an inlet port and an outlet port in fluid connection with the channel. The channel may be configured to pass a first heat transfer medium between the inlet port and outlet port. The housing may include a plurality of surface features extending inwards from the inner wall and toward the plurality of clutch discs. The plurality of surface features is configured to transfer heat from second heat transfer medium to the housing, thereby transferring heat away from the plurality of clutch discs. The channel may be configured to transfer heat from the housing to the first heat transfer medium, thereby transferring heat away from the housing. |
| FILED | Monday, December 14, 2015 |
| APPL NO | 14/967476 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/107 (20130101) F02C 7/36 (20130101) Jet-propulsion Plants F02K 3/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/36 (20130101) F05D 2220/90 (20130101) F05D 2220/328 (20130101) F05D 2260/20 (20130101) F05D 2260/4023 (20130101) F05D 2260/22141 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 13/72 (20130101) Original (OR) Class Climate Change Mitigation Technologies Related to Transportation Y02T 50/671 (20130101) Y02T 50/675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520197 | Dziech et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Aaron Michael Dziech (Crittenden, Kentucky); Megan Elizabeth Scheitlin (Cincinnati, Ohio) |
| ABSTRACT | Combustor assemblies and methods for assembling combustor assemblies are provided. For example, a combustor assembly comprises an annular inner liner and an annular outer linear, each extending generally along an axial direction. The outer liner includes an outer flange extending forward from its upstream end. The combustor assembly also comprises a combustor dome extending between an inner liner upstream end and the outer liner upstream end and including an inner flange extending forward from a radially outermost end of the combustor dome. The inner liner, outer liner, and combustor dome define a combustion chamber therebetween, and the combustor dome and a portion of the outer liner together define an annular cavity of the combustion chamber. The inner and outer flanges define an airflow opening therebetween, and a chute member is positioned within the airflow opening to define an air chute for providing a flow of air to the annular cavity. |
| FILED | Thursday, June 01, 2017 |
| APPL NO | 15/610937 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/007 (20130101) F23R 3/10 (20130101) F23R 3/58 (20130101) Original (OR) Class F23R 3/60 (20130101) F23R 2900/00015 (20130101) F23R 2900/00017 (20130101) F23R 2900/03042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520272 | Carson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Robert Carson (Watervliet, New York); David Marshall (Ballston Lake, New York); Tyler Bellamy (Cropseyville, New York); Stephen Robertson (Cambridge, New York) |
| ABSTRACT | Openings in a muzzle brake provide recoil inhibition and impulse noise attenuation by redirecting the propellant gases to the external environment. A turning vane aggressively turns and redirects the propellant gases in a rearward direction to counter the recoil of the weapon system. An angled baffle provides a physical barrier to redirect propellant gases rearward to provide additional force to counteract the recoil force. Attenuation slits mitigate blast overpressure by producing a fluid barrier of high velocity propellant gases directed radially away from the muzzle brake. The fluid barrier from the attenuation slits interacts with the redirected propellant gas from the turning vane and the angled baffle and redirects the counter recoil gases away from the crew. |
| FILED | Friday, March 23, 2018 |
| APPL NO | 15/933665 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/36 (20130101) Original (OR) Class F41A 21/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520291 | Vasudevan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Srikanth Vasudevan (Shelton, Connecticut); Paul Suchy (Parma, Ohio); Matthew C. Birch (Madison, Alabama) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Srikanth Vasudevan (Shelton, Connecticut); Paul Suchy (Parma, Ohio); Matthew C. Birch (Madison, Alabama) |
| ABSTRACT | Methods involve using a guided munition (e.g., a mortar round or a grenade) that utilizes deployable flow effectors, activatable flow effectors and/or active flow control devices to extend the range and enhance the precision of traditional unguided munitions without increasing the charge needed for launch. Sensors such as accelerometers, magnetometers, IR sensors, rate gyros, and motor controller sensors feed signals into a controller which then actuates or deploys the flow effectors/flow control devices to achieve the enhanced characteristics. |
| FILED | Monday, March 05, 2018 |
| APPL NO | 15/911265 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/14 (20130101) F42B 10/44 (20130101) F42B 10/62 (20130101) F42B 15/01 (20130101) Original (OR) Class F42B 30/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520355 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures, Inc. (Lincoln, Nebraska); The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | NUTECH VENTURES, Inc. (Lincoln, Nebraska); The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Ming Han (Lincoln, Nebraska); Guigen Liu (Lincoln, Nebraska); Weilin Hou (Slidell, Louisiana); Qiwen Sheng (Haslett, Michigan) |
| ABSTRACT | A fiber optic sensor, a process for utilizing a fiber optic sensor, and a process for fabricating a fiber optic sensor are described, where a double-side-polished silicon pillar is attached to an optical fiber tip and forms a Fabry-Pérot cavity. In an implementation, a fiber optic sensor in accordance with an exemplary embodiment includes an optical fiber configured to be coupled to a light source and a spectrometer; and a single silicon layer or multiple silicon layers disposed on an end face of the optical fiber, where each of the silicon layer(s) defines a Fabry-Pérot interferometer, and where the sensor head reflects light from the light source to the spectrometer. In some implementations, the fiber optic sensor may include the light source coupled to the optical fiber, a spectrometer coupled to the optical fiber, and a controller coupled to the high-speed spectrometer. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 15/919326 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/6884 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/004 (20130101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/32 (20130101) G01K 13/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10520393 — System and method for verifying a diopter setting and range of an optical system eyepiece
| US 10520393 | Spahr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Erik J. Spahr (Hollis, New Hampshire); David L. Masters (Tyngsboro, Massachusetts) |
| ABSTRACT | The present disclosure relates to a system and method for verifying a diopter setting and range of an optical system eyepiece by utilizing an image sensor to view and analyze test patterns of spots displayed within the optical system eyepiece and calculating the diopter setting and range of the optical system eyepiece from an observed change in the test pattern at different diopter settings. |
| FILED | Thursday, August 10, 2017 |
| APPL NO | 15/767536 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 11/0228 (20130101) Original (OR) Class G01M 11/0264 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520459 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Universitat Autonoma de Barcelona (Bellaterra, Spain) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Joseph Wang (San Diego, California); Joshua Ray Windmiller (Del Mar, California); Aoife O'Mahony (San Diego, California); Xavier Cetó (La Figuerosa, Spain); Manel Del Valle (Terrassa, Spain) |
| ABSTRACT | Methods, systems, and devices are disclosed for the identification of chemical agents and determination of their level of exposure using electrochemical detection and advanced signal processing. In one aspect, a method includes collecting a sample from a surface containing a chemical agent to an electrode on a sensor such that the chemical agent transfers on the electrode, detecting an electrochemical signal of the chemical agent on the electrode to transduce chemical information associated with the chemical agent to an electrical signal, processing the electrical signal to obtain electrochemical spectral signature data to identify the chemical agent and generating a series of coefficients of the electrochemical spectral signature data to reduce the data, and classifying the chemical information based on the series of coefficients among preselected data sets to determine a level of exposure to the chemical agent. |
| FILED | Wednesday, June 07, 2017 |
| APPL NO | 15/616660 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/48 (20130101) G01N 27/307 (20130101) Original (OR) Class G01N 33/0057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520524 | Griffin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| ASSIGNEE(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| INVENTOR(S) | Riley Griffin (Manassas, Virginia); Michael Lieu (Manassas, Virginia) |
| ABSTRACT | Disclosed herein is a distributed pressure sensor system that quickly detects and counters changes in lift, onset of stall, and flutter. The distributed pressure sensor system may employ a plurality of integrated pressure ports distributed across the span of a wing's leading edge to gather differential pressure measurements. Based on the differential pressure measurements, the distributed pressure sensor system can estimate torque on the fuselage to provide a more efficient estimate for changes in lift, onset of stall, and/or flutter. These estimates may be applied as feedback to the aircraft's control system, thereby eliminating the latency in the existing platform dynamics. |
| FILED | Friday, February 02, 2018 |
| APPL NO | 15/887075 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/14 (20130101) Original (OR) Class G01P 5/16 (20130101) G01P 5/165 (20130101) G01P 13/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520600 | Hyland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John C. Hyland (Panama City, Florida); Cheryl Smith (Panama City, Florida) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John C. Hyland (Panama City, Florida); Cheryl Smith (Panama City, Florida) |
| ABSTRACT | Methods for segmenting an ocean bottom area into multiple homogenous, rectangular sub-mission areas and generating new, composite sensor performance functions for each sub-mission area are provided. The method discretizes each voxel into a plurality of equally sized, square range bins and obtains a mean P-of-Y curve for each row and column based on a bottom characterization for each of the voxels. Zone parameters along each direction are iteratively calculated, with adjacent zones merged when their parameters are within predetermined values. Pooled variances are calculated for each direction and a preferred mission direction is chosen based on the direction with the smallest pooled variance. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/467702 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/89 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520720 | Hall |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America, as represented by the Secretary of the Army (Fort Belvoir, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| INVENTOR(S) | John M. Hall (Stafford, Virginia) |
| ABSTRACT | A novel optical design form for a biocular lens arrangement having a large format focal plane and large eye relief zone is disclosed. Key aspects of a large format biocular lens arrangement are: Lightweight plastic design for all but outermost lens, where more durable glass is desired; a large front aperture for comfortable eye motion; improved eye channel overlapping field of view with minimal distortion; and full color resolution. |
| FILED | Monday, June 05, 2017 |
| APPL NO | 15/613332 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 25/001 (20130101) Original (OR) Class G02B 25/04 (20130101) G02B 27/025 (20130101) G02B 27/0172 (20130101) G02B 2027/0132 (20130101) G02B 2027/0136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10521002 | Eastep et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
| ASSIGNEE(S) | INTEL CORPORATION (Santa Clara, California) |
| INVENTOR(S) | Jonathan M. Eastep (Portland, Oregon); Rohit Banerjee (Portland, Oregon); Richard J. Greco (West Lin, Oregon); Ilya Sharapov (San Jose, California); David N. Lombard (Rossmoor, California); Hari K. Nagpal (Southborough, Massachusetts) |
| ABSTRACT | Apparatus, systems, and methods provide dynamic spatial power steering among a plurality of power domains in the computer system on a per phase basis of a particular application. Dynamic spatial power steering may include, for example, determining a plurality of phases corresponding to an application comprising tasks for execution on a processing node. determining a spatial power distribution between a plurality of power domains on the processing node based on a performance metric for each phase, monitoring the application to detect a current phase, and applying the spatial power distribution correspond to the current phase to the plurality of power domains. |
| FILED | Thursday, October 19, 2017 |
| APPL NO | 15/788195 |
| ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/3206 (20130101) G06F 1/3234 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10521390 | Linderman et al. |
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| FUNDED BY |
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| APPLICANT(S) | GOVERMENT OF THE UNITED STATES AS REPRESENTED BY SECRETARY OF THE AIR FORCE (Rome, New York) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Mark H Linderman (Rome, New York); Qing Wu (Manlius, New York); Dennis Fitzgerald (Sauquoit, New York) |
| ABSTRACT | An apparatus for a microprocessor computer system and method for configuring the same where said microprocessor computer system comprises a processor core and at least one hardware buffer FIFO with memory-mapped head and tail that handles data movement among the processor cores, networks, raw data input and outputs, and memory. The method for configuring said microprocessor computer system comprises utilizing a FIFO auxiliary processor to process said data traversing said hardware FIFO; utilizing said hardware FIFOs to efficiently pipe data through functional blocks; and utilizing a FIFO controller to perform DMA operations that include non-unit-stride access patterns and transfers among processor cores, networks, raw data input and outputs, memory, and other memory-mapped hardware FIFOs. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804525 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 13/404 (20130101) Original (OR) Class G06F 13/4022 (20130101) G06F 13/4031 (20130101) G06F 13/4081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10521714 | Esser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Steven K. Esser (San Jose, California); Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | Embodiments of the invention provide a neural core circuit comprising a synaptic interconnect network including plural electronic synapses for interconnecting one or more source electronic neurons with one or more target electronic neurons. The interconnect network further includes multiple axon paths and multiple dendrite paths. Each synapse is at a cross-point junction of the interconnect network between a dendrite path and an axon path. The core circuit further comprises a routing module maintaining routing information. The routing module routes output from a source electronic neuron to one or more selected axon paths. Each synapse provides a configurable level of signal conduction from an axon path of a source electronic neuron to a dendrite path of a target electronic neuron. |
| FILED | Thursday, January 21, 2016 |
| APPL NO | 15/003703 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 9/44505 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Original (OR) Class G06N 3/049 (20130101) G06N 3/063 (20130101) G06N 3/088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522326 | Walsh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael Patrick Walsh (Somerville, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | A method of locating a substrate within a field of view of an imaging system includes acquiring an image of a first marker on a substrate in the field of view. The first marker has a first spatial pattern representing a position of the first marker relative to the substrate. The method also includes determining possible positions of the substrate based on the first spatial pattern and moving the substrate relative to the field of view based on the possible positions of the substrate. The method also includes acquiring an image of a second marker on the substrate in the field of view. The second marker has a second pattern representing a position of the second marker relative to the substrate. The method further includes determining the position of the substrate relative to the field of view based on the position of the second marker on the substrate. |
| FILED | Wednesday, February 14, 2018 |
| APPL NO | 15/896377 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) Optical Elements, Systems, or Apparatus G02B 21/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/28 (20130101) Original (OR) Class H01J 37/222 (20130101) H01J 37/3023 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/68 (20130101) H01L 23/544 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522714 | Shatalov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sensor Electronic Technology, Inc. (Columbia, South Carolina) |
| ASSIGNEE(S) | Sensor Electronic Technology, Inc. (Columbia, South Carolina) |
| INVENTOR(S) | Maxim S. Shatalov (Columbia, South Carolina); Alexander Dobrinsky (Loudonville, New York); Michael Shur (Latham, New York); Remigijus Gaska (Columbia, South Carolina) |
| ABSTRACT | An interface including roughness components for improving the propagation of radiation through the interface is provided. The interface includes a first profiled surface of a first layer comprising a set of large roughness components providing a first variation of the first profiled surface having a first characteristic scale and a second profiled surface of a second layer comprising a set of small roughness components providing a second variation of the second profiled surface having a second characteristic scale. The first characteristic scale is approximately an order of magnitude larger than the second characteristic scale. The surfaces can be bonded together using a bonding material, and a filler material also can be present in the interface. |
| FILED | Monday, August 21, 2017 |
| APPL NO | 15/682031 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/68 (20130101) C30B 29/403 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/16 (20130101) Original (OR) Class H01L 33/22 (20130101) H01L 33/58 (20130101) H01L 33/0079 (20130101) H01L 2933/0083 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0224 (20130101) H01S 5/34333 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522850 | Gould et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Benjamin D. Gould (Alexandria, Virginia); Ravi Ramamurti (Silver Spring, Maryland); Karen Swider-Lyons (Alexandria, Virginia); Michael Schuette (Vienna, Virginia); Joseph Rodgers (Jessup, Maryland); Chris Netwall (Annandale, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin D. Gould (Alexandria, Virginia); Ravi Ramamurti (Silver Spring, Maryland); Karen Swider-Lyons (Alexandria, Virginia); Michael Schuette (Vienna, Virginia); Joseph Rodgers (Jessup, Maryland); Chris Netwall (Annandale, Virginia) |
| ABSTRACT | A bipolar plate for a fuel cell is provided. The bipolar plate includes a main body with a first end and a second end spaced from the first end along a longitudinal axis of the main body. At least one inlet is disposed at the first end of the main body. At least one outlet corresponding to the at least one inlet is disposed at the second end of the main body. At least one continuous flow path extends from the at least one inlet to the at least one outlet. The main body comprises a single, contiguous piece. |
| FILED | Tuesday, September 29, 2015 |
| APPL NO | 14/868513 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 3/1055 (20130101) B22F 2003/242 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Alloys C22C 1/0458 (20130101) C22C 14/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/02 (20130101) C23C 8/24 (20130101) C23C 14/165 (20130101) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/16 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/026 (20130101) Original (OR) Class H01M 8/0208 (20130101) H01M 8/0232 (20130101) H01M 8/0247 (20130101) H01M 8/0258 (20130101) H01M 8/0263 (20130101) H01M 8/0267 (20130101) H01M 2008/1095 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522889 | Rowland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jason F. Rowland (San Diego, California); Jia-Chi S. Chieh (San Diego, California) |
| ABSTRACT | A tunable notch filter comprising a transmission line, a tunable bandstop filter and a tunable bandpass filter. The transmission line has an input port, an output port and a length electrically connecting the input port to the output port and receiving an RF signal at the input port. The tunable bandstop filter comprises a first direct current voltage source, a first coupling line and a first tunable capacitor. The first direct current voltage source provides a first adjustable voltage to the first tunable capacitor. The first tunable capacitor adjusts its capacitance based on the first adjustable voltage. The tunable bandpass filter comprises a second direct current voltage source, a second coupling line and a second tunable capacitor. The second direct current voltage source provides a second adjustable voltage to second tunable capacitor. The second tunable capacitor adjusts its capacitance based on the second adjustable voltage. |
| FILED | Monday, April 09, 2018 |
| APPL NO | 15/947906 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/203 (20130101) Original (OR) Class H01P 3/08 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/01 (20130101) H03H 7/0115 (20130101) H03H 2007/013 (20130101) H03H 2210/012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522903 | Parkins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Red Tail Hawk Corporation (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Red Tail Hawk Corporation (Philadelphia, Pennsylvania) |
| INVENTOR(S) | John W. Parkins (Philadelphia, Pennsylvania) |
| ABSTRACT | A magnetic field transmitter, especially a transmitter used in conjunction with wireless communications earplugs. In one embodiment, a plate of magnetic material is used behind a coil of electrical conductor to improve the efficiency of the transmitter and to provide electrical and magnetic shielding. The specific dimensions and characteristics of the preferred embodiment of the transmitter described herein provide for efficient wireless communications. |
| FILED | Friday, December 23, 2016 |
| APPL NO | 15/389973 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 11/08 (20130101) Antennas, i.e Radio Aerials H01Q 1/273 (20130101) Original (OR) Class H01Q 1/2291 (20130101) H01Q 7/06 (20130101) Transmission H04B 5/0006 (20130101) H04B 5/0075 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/1008 (20130101) H04R 1/1075 (20130101) H04R 1/1091 (20130101) H04R 25/554 (20130101) H04R 2209/022 (20130101) H04R 2420/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522918 | Jablon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Allan R. Jablon (Ellicott City, Maryland); Gerald F. Ricciardi (Mount Airy, Maryland) |
| ABSTRACT | Example apparatuses and methods relating to antennas are provided. An example apparatus in the form of an antenna assembly includes a first conductor formed into a first helical structure wound around a central axis and a second conductor formed into a second helical structure wound around the central axis. The first helical structure may have a first coil sense and the second helical structure may have second coil sense that is opposite the first coil sense. The first conductor may have a first conductor proximal end and a first conductor distal end and the second conductor may have a second conductor proximal end and a second conductor distal end. The first conductor distal end may be adjacent the second conductor proximal end. The antenna assembly may further include first, second, and third ground planes with one disposed at each end of the conductors and one disposed between the conductors. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/387636 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/24 (20130101) H01Q 1/48 (20130101) H01Q 3/247 (20130101) H01Q 11/08 (20130101) H01Q 11/083 (20130101) Original (OR) Class H01Q 21/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522965 | Suelzer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph S. Suelzer (Dayton, Ohio); Nicholas G. Usechak (Oakwood, Ohio); Preetpaul S. Devgan (Oakwood, Ohio); Thomas B. Simpson (San Diego, California) |
| ABSTRACT | A system and method for generating optically synthesized microwave signals with broadband tunability is disclosed. The system includes a first laser and a second laser, where the first laser and second laser are optically coupled to each other. The second laser is operable to receive optical signals injected by the first laser, and to output optical signals via one or more feedback paths. The system provides for singular or mutual optical injection. A photodetector is optically coupled to the second laser over the one or more feedback paths, and operable to convert optical signals to electrical signals. A phase modulator is coupled to the photodetector, where the electrical signals from the photodetector are operable to drive the phase modulator and close the one or more feedback paths. The respective lengths of the feedback paths may be selected such that their corresponding lengths provide a frequency spacing for optical signals therein that is significantly smaller than a frequency of microwave signals. |
| FILED | Thursday, August 09, 2018 |
| APPL NO | 16/059400 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/005 (20130101) H01S 3/1305 (20130101) H01S 3/10092 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10523156 | Kang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Jongchan Kang (Moorpark, California); Ara K. Kurdoghlian (La Canada, California) |
| ABSTRACT | A unit cell for a resistive mixer includes a plurality of active devices arranged in series, wherein each of said plurality of active devices having a different output conductance. A resistive mixer includes a plurality of active devices connected in series with one another to form a unit cell. |
| FILED | Thursday, June 29, 2017 |
| APPL NO | 15/637286 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 19/14 (20130101) Demodulation or Transference of Modulation From One Carrier to Another H03D 7/1441 (20130101) Original (OR) Class H03D 7/1458 (20130101) H03D 7/1466 (20130101) H03D 9/0675 (20130101) H03D 2200/0088 (20130101) Transmission H04B 1/0475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10523209 | Wang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Flex Logix Technologies, Inc. (Mountain View, California) |
| ASSIGNEE(S) | Flex Logix Technologies, Inc. (Mountain View, California) |
| INVENTOR(S) | Cheng C. Wang (San Jose, California) |
| ABSTRACT | An integrated circuit comprising a plurality of logic tiles, wherein, during operation, each logic tile is configurable to connect with at least one other logic tile, and wherein each logic tile includes: (1) a normal operating mode, (2) a test mode, (3) an interconnect network including a plurality of multiplexers, wherein during operation, the interconnect network of each logic tile is configurable to electrically connect with the interconnect network of at least one adjacent logic tile of the plurality of logic tiles via one or more tile-to-tile interconnects in the normal operating mode and (4) isolation circuitry, connected between the associated interconnect network and the interconnect network of each adjacent logic tile, configurable to responsively disconnect tile-to-tile interconnects disposed between the interconnect network of each adjacent logic tile in the test mode to thereby electrically disconnect interconnect networks of adjacent logic tiles in the test mode. |
| FILED | Monday, November 12, 2018 |
| APPL NO | 16/186882 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3177 (20130101) Pulse Technique H03K 19/1737 (20130101) H03K 19/17728 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10523214 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HQPHOTONICS INC. (Pasadena, California) |
| ASSIGNEE(S) | HQPHOTONICS INC. (Pasadena, California) |
| INVENTOR(S) | Jiang Li (Pasadena, California); Kerry Vahala (Pasadena, California) |
| ABSTRACT | A voltage-controlled oscillator generates a VCO output signal at frequency fM. A dual optical-frequency source generates optical signals at frequencies v1S and v2S. An electro-optic frequency divider (EOFD) generates multiple optical sidebands spaced by fM, and from two sidebands generates a beat signal at beat frequency δf. A first control circuit generates an error signal from the beat signal and a first reference signal at frequency fREF1, and couples the VCO and the EOFD in a negative feedback arrangement that stabilizes the output frequency fM. A second control circuit generates an error signal from the frequency-divided output signal and a second reference signal at frequency fREF2, and couples the VCO and one or both of the dual source or the first reference signal in a negative feedback arrangement that stabilizes, or compensates for fluctuations of, a difference frequency v2S−v1S. |
| FILED | Saturday, April 28, 2018 |
| APPL NO | 15/965911 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/302 (20130101) H01S 3/1109 (20130101) H01S 3/1305 (20130101) H01S 3/06708 (20130101) H01S 3/094049 (20130101) H01S 3/094096 (20130101) H01S 5/065 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 5/00 (20130101) H03L 7/06 (20130101) Original (OR) Class Transmission H04B 10/503 (20130101) H04B 10/2504 (20130101) H04B 10/2507 (20130101) H04B 2210/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10523777 | Yeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | NORTHEASTERN UNIVERSITY (Boston, Massachusetts); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Edmund Meng Yeh (Newton, Massachusetts); Ying Cui (Shaanxi, China PRC); Ran Liu (Heilongjiang, China PRC); Tracey Ho (Pasadena, California); Michael Burd (Lees Summit, Missouri); Derek Leong (Singapore, Singapore) |
| ABSTRACT | A system and method for joint dynamic interest request forwarding and dynamic cache placement and eviction and provided within the context of the Named Data Networking (NDN) architecture. The system and method employ a virtual control plane that operates on the user demand rate for data objects in the network, and an actual plane that handles Interest Packets and Data Packets. Distributed algorithms within the virtual plane achieve network load balancing through dynamic forwarding and caching, thereby maximizing the user demand rate that the NDN network can satisfy. A method of congestion control is also provided to achieve optimal network fairness using the VIP framework. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 15/022251 |
| ART UNIT | 2449 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/02 (20130101) H04L 45/64 (20130101) H04L 45/586 (20130101) H04L 47/27 (20130101) H04L 67/2842 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10523884 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Voxtel, inc. (Beaverton, Oregon) |
| ASSIGNEE(S) | LadarSystems, Inc. (Beaverton, Oregon) |
| INVENTOR(S) | Adam Lee (Portland, Oregon); George Williams (Portland, Oregon); Jehyuk Rhee (King City, Oregon) |
| ABSTRACT | An imaging device in accordance with the present disclosure comprises of a pixelated array of semiconductor detector elements, each of the pixels in the array having an in-pixel integrated circuit, the integrated circuit having a comparator, a readout decoder block, and an address arbitration control block. The readout decoder block reads out the integrated signals of the pixels. The address arbitration control block determines the pixel address of the pixels charging beyond a threshold voltage, the threshold exceedance determined by the comparator. The addressed pixels are provided a timestamp for each of the pixels integrating beyond the threshold voltage, the timestamp provided by an off-pixel time-to-digital converter (TDC), the value of the timestamp corresponding with the accumulated charge of the pixel. |
| FILED | Thursday, January 29, 2015 |
| APPL NO | 14/609295 |
| ART UNIT | 2698 — Selective Visual Display Systems |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/378 (20130101) Original (OR) Class H04N 5/3745 (20130101) H04N 5/37455 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524059 | Najafi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Khalil Najafi (Ann Arbor, Michigan); Yemin Tang (Ann Arbor, Michigan) |
| ABSTRACT | Techniques are presented for fabricating transducers and other types of microstructures having high aspect ratios. To achieve high aspect ratios, wafers are etched from both sides for example using deep reactive ion etching. The three-dimensional structure is designed to have an overall footprint less than four hundred micrometers with a thickness on the order of 0.5-2 millimeters as compared to conventional planar devices. |
| FILED | Friday, July 01, 2016 |
| APPL NO | 15/740986 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00269 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 17/00 (20130101) H04R 17/02 (20130101) H04R 19/00 (20130101) H04R 19/04 (20130101) H04R 19/005 (20130101) Original (OR) Class H04R 31/00 (20130101) H04R 2201/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524344 | Milchberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Howard M. Milchberg (Potomac, Maryland); Andrew Goers (Adelphi, Maryland); George Hine (College Park, Maryland); Fatholah Salehi (Hyattsville, Maryland); Linus Feder (Washington, District of Columbia); Bo Miao (College Park, Maryland) |
| ABSTRACT | A laser-plasma-based acceleration system includes a focusing element and a laser pulse emission directing a laser beam to the focusing element to such that laser pulses transform into a focused beam and a chamber defining a nozzle having a throat and an exit orifice, emitting a critical density range gas jet from the exit orifice for laser wavelengths ranging from ultraviolet to the mid-infrared. the critical density range gas jet intersects the focused beam at an angle and in proximity to the exit orifice of the nozzle to define a point of intersection between the focused beam and the critical density range gas jet. In intersection with the critical density range gas jet, the pulsed focused beam drives a laser plasma wakefield relativistic electron beam. A corresponding method of laser-plasma-based acceleration is also described. The critical density range may include 2×1020 cm−3 to 5×1021 cm−3. |
| FILED | Monday, May 15, 2017 |
| APPL NO | 15/595675 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/003 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 35/00 (20130101) X-ray Technique H05G 2/003 (20130101) H05G 2/008 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10517626 | Lal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Amit Lal (Ithaca, New York); Fabrizio Michelassi (New York, New York); Po-Cheng Chen (Ithaca, New York); Connie Wu (Princeton, New Jersey) |
| ABSTRACT | Devices, systems, and techniques are disclosed for intelligent semiconductor based medical tweezers and instrumentation including microscale sensors, actuators and circuitry for tissue detection and characterization. In one aspect, a tweezer device includes a hinge structure to enable tweezing motion of the device for clamping a sample, two leg components coupled to the hinge structure, a plurality of microprobes configured on both of the two leg components, and an electronic circuit electrically coupled to the microprobes to process and/or transmit the electronic signals. The microprobes include sensors in a sensing tip structured to penetrate into the sample when the device clamps the sample and produce electronic signals from the sensors of a property of the sample, the sensors of the sensing tip including at least one of an electrode to measure an electrical potential, an electrical permittivity sensor to measure electrical permittivity, or a strain gauge to measure mechanical compliance. |
| FILED | Thursday, August 07, 2014 |
| APPL NO | 14/910660 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/30 (20130101) Original (OR) Class A61B 2017/0011 (20130101) A61B 2017/00026 (20130101) A61B 2017/00221 (20130101) A61B 2017/305 (20130101) A61B 2017/320093 (20170801) A61B 2017/320094 (20170801) A61B 2017/320097 (20170801) A61B 2560/0214 (20130101) A61B 2562/0261 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517822 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Chicago (Chicago, Illinois); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Wenbin Lin (Chicago, Illinois); Chunbai He (Chicago, Illinois); Demin Liu (Round Lake, Illinois) |
| ABSTRACT | Nanoscale coordination polymer nanoparticles for the co-delivery of multiple therapeutic agents are described. The multiple therapeutic agents can include a combination of different chemotherapeutic agents, a combination of one or more chemotherapeutic agents and one or more nucleic acids, such as small interfering RNA (siRNA) or microRNA, a combination of one or more chemotherapeutic agents and a photosensitizer (i.e., for use in photodynamic therapy), or a plurality of different siRNAs. Pharmaceutical formulations including the nanoparticles, methods of using the nanoparticles to treat cancer, and methods of making the nanoparticles are also described. |
| FILED | Thursday, November 06, 2014 |
| APPL NO | 15/034799 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) Original (OR) Class A61K 31/664 (20130101) A61K 31/713 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517824 | DeSimone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Belmont, Massachusetts); Benjamin W. Maynor (Durham, North Carolina); Larken E. Euliss (Agoura Hills, California); Ginger Denison Rothrock (Durham, North Carolina); Ansley E. Dennis (Augusta, Georgia); Edward T. Samulski (Chapel Hill, North Carolina); R. Jude Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/846827 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) Original (OR) Class A61K 9/0097 (20130101) A61K 9/5138 (20130101) A61K 9/5153 (20130101) A61K 9/5192 (20130101) A61K 47/34 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 99/0085 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0004 (20130101) H01L 51/0021 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/3154 (20150401) Y10T 428/24273 (20150115) Y10T 428/24479 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10517952 | Finn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | M. G. Finn (Atlanta, Georgia); Cody James Higginson (Union City, California) |
| ABSTRACT | Disclosed herein are degradable materials comprising the reaction product of an oxanorbornadiene crosslinker or derivative thereof and a multivalent nucleophile-terminated compound, wherein the reaction product is a degradable elastic solid capable of entraining cargo. Also disclosed herein are degradable materials comprising a polymeric and hyperbranched crosslinked material made with oxanorbornadiene linkage that can be activated for cleavage at a predetermined rate by addition of a nucleophile. Also disclosed herein are methods of making and using the same. |
| FILED | Wednesday, December 02, 2015 |
| APPL NO | 15/532911 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 9/0024 (20130101) A61K 47/34 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/62 (20130101) A61L 27/58 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/0273 (20130101) C08G 75/045 (20130101) C08G 2210/00 (20130101) C08G 2230/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10518230 | Weitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David A. Weitz (Bolton, Massachusetts); Mark Romanowsky (Cambridge, Massachusetts); Adam R. Abate (Daly City, California) |
| ABSTRACT | Parallel uses of microfluidic methods and devices for focusing and/or forming discontinuous sections of similar or dissimilar size in a fluid are described. In some aspects, the present invention relates generally to flow-focusing-type technology, and also to microfluidics, and more particularly parallel use of microfluidic systems arranged to control a dispersed phase within a dispersant, and the size, and size distribution, of a dispersed phase in a multi-phase fluid system, and systems for delivery of fluid components to multiple such devices. |
| FILED | Friday, October 07, 2016 |
| APPL NO | 15/288135 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 3/0811 (20130101) B01F 13/0062 (20130101) Original (OR) Class B01F 2215/0037 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) B01J 2219/00015 (20130101) B01J 2219/0097 (20130101) B01J 2219/00783 (20130101) B01J 2219/00828 (20130101) B01J 2219/00831 (20130101) B01J 2219/00833 (20130101) B01J 2219/00837 (20130101) B01J 2219/00889 (20130101) B01J 2219/00891 (20130101) B01J 2219/00975 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) B01L 2200/0636 (20130101) B01L 2200/0673 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) Y10T 137/8593 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10518331 | Mirkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Matthew R. Jones (LaMesa, California); Matthew N. O'Brien (Plymouth, Minnesota) |
| ABSTRACT | Methods of synthesizing various metal nanoparticle structures having high uniformity, using iterative reduction and oxidation conditions, is provided herein. |
| FILED | Monday, July 13, 2015 |
| APPL NO | 15/324283 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0048 (20130101) B22F 9/24 (20130101) Original (OR) Class B22F 2001/0033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519035 | Dwyer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rhode Island Council on Postsecondary Education (Warwick, Rhode Island) |
| ASSIGNEE(S) | Rhode Island Council On Postsecondary Education (Warwick, Rhode Island) |
| INVENTOR(S) | Jason R. Dwyer (Providence, Rhode Island); Y. M. Nuwan D. Y. Bandara (Kingston, Rhode Island); Buddini Iroshika Karawdeniya (Kingston, Rhode Island); Julie C. Whelan (Shannock, Rhode Island) |
| ABSTRACT | The invention provides a method to form and functionalize monolayers on a silicon-rich silicon nitride surface or a silicon surface formed by a nanopore fabrication method known as dielectric breakdown. Thermal, photochemical and radical processing can be used to hydrosilylate nascent silicon and silicon nitride surfaces with various reagents. The conventional need for hydrofluoric acid etching prior to coupling functional groups to the surfaces is thereby completely avoided. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 15/900762 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00206 (20130101) Original (OR) Class Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 11/32 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02118 (20130101) H01L 21/02258 (20130101) H01L 21/02307 (20130101) H01L 21/02321 (20130101) H01L 21/02359 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519076 | Buckner et al. |
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| FUNDED BY |
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| APPLICANT(S) | Steven Wayne Buckner (St. Louis, Missouri); Paul Jelliss (St. Louis, Missouri); Stephen Chung (Florissant, Missouri); Jacob M. Laktas (St. Louis, Missouri); Gregory J. Place (St. Louis, Missouri) |
| ASSIGNEE(S) | Saint Louis University (Saint Louis, Missouri) |
| INVENTOR(S) | Steven Wayne Buckner (St. Louis, Missouri); Paul Jelliss (St. Louis, Missouri); Stephen Chung (Florissant, Missouri); Jacob M. Laktas (St. Louis, Missouri); Gregory J. Place (St. Louis, Missouri) |
| ABSTRACT | The present invention generally concerns isolated nanoparticles via the decomposition of a ternary metal hydride. More specifically, the present invention harnesses increased energy densities from two distinct nanoparticles isolated by a precise decomposition of LiAlH4. The singular material is air stable and is a nanocomposite of Li3AlH6 nanoparticles, elemental Al nanoparticles, an amount of Ti metal, and a nanoscale organic layer, which we call nMx. The nanocomposite protects and preserves the high energy densities of the core metals isolated from the controlled reaction and makes the nanoparticles safe to handle in air. The final composite is devoid of byproducts or phase transitions that will decrease the energy output of the nanocomposite. The method of the present invention creates a narrow distribution of nanoparticles that have unique burning characteristics useful for many applications. |
| FILED | Wednesday, December 27, 2017 |
| APPL NO | 15/932062 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/0078 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 45/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519172 | Szymczak et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Nathaniel Szymczak (Ypsilanti, Michigan); Jacob Geri (Ann Arbor, Michigan) |
| ABSTRACT | Disclosed herein are borazine complexes and use of the same in perfluoroalkylation reactions. |
| FILED | Friday, June 23, 2017 |
| APPL NO | 16/308304 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 37/02 (20130101) C07B 39/00 (20130101) C07B 47/00 (20130101) Acyclic or Carbocyclic Compounds C07C 17/278 (20130101) C07C 29/64 (20130101) C07C 209/52 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/05 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/582 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10519265 — Polymeric materials having active cross-linkers, methods for making them, and use thereof
| US 10519265 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| INVENTOR(S) | Ye Zhang (Waltham, Massachusetts); Bing Xu (Newton, Massachusetts) |
| ABSTRACT | The present technology relates to a polymeric material including a plurality of polymer subunits and an active cross-linker, wherein the active cross-linker is covalently linked to the plurality of polymer subunits. The active cross-linker offers a key building block for constructing novel molecular architecture in chemomechanical soft materials and illustrates a new approach to tailor material properties. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 15/923755 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0053 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/54 (20130101) Original (OR) Class C08F 226/02 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/20 (20130101) C08K 5/0025 (20130101) C08K 5/0091 (20130101) Compositions of Macromolecular Compounds C08L 33/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519278 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (Baton Rouge, Louisiana) |
| INVENTOR(S) | Donghui Zhang (Baton Rouge, Louisiana); Jinbao Cao (Baton Rouge, Louisiana); Brandon Chan (Baton Rouge, Louisiana); David Siefker (Baton Rouge, Louisiana) |
| ABSTRACT | Various embodiments disclosed relate to a method of forming a polypeptide. The method includes contacting a first amino acid-derived N-thiocarboxyanhydrosulfide monomer as a crystalline solid with a polymerization initiator (e.g., in an alkane suspension) to give a polypeptide product. The method further includes contacting the polypeptide product with a second amino acid-derived N-thiocarboxyanhydrosulfide monomer in an alkane suspension. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/687397 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/00 (20130101) Original (OR) Class C08G 69/04 (20130101) C08G 69/10 (20130101) C08G 69/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519451 | Khvorova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); BETH ISRAEL DEACONESS MEDICAL CENTER (Boston, Massachusetts) |
| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Melissa Moore (Chestnut Hill, Massachusetts); Anton A. Turanov (Boston, Massachusetts); Ananth Karumanchi (Chestnut Hill, Massachusetts) |
| ABSTRACT | This disclosure relates to novel targets for angiogenic disorders. Novel oligonucleotides are also provided. Methods of using the novel oligonucleotides for the treatment of angiogenic disorders (e.g., preeclampsia) are also provided. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 15/814350 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/50 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/344 (20130101) C12N 2310/346 (20130101) C12N 2310/351 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519453 | Smolke et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Christina D. Smolke (Menlo Park, California); Catherine Thodey (Mountain View, California); Isis Trenchard (Redwood City, California) |
| ABSTRACT | Methods and engineered yeast cells for generating a benzylisoquinoline alkaloid product are provided herein. A method comprises providing engineered yeast cells and a feedstock to a reactor. In the reactor, the engineered yeast cells are subjected to fermentation by incubating the engineered yeast cells for a time period to produce a solution comprising the BIA product and cellular material. The solution comprises not more than one class of molecule selected from the group of protoberberine, morphinan, isopavine, aporphine, and benzylisoquinoline. Additionally, at least one separation unit is used to separate the BIA product from the cellular material to provide the product stream comprising the BIA product. |
| FILED | Friday, October 19, 2018 |
| APPL NO | 16/165940 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Heterocyclic Compounds C07D 217/18 (20130101) C07D 217/22 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/52 (20130101) Original (OR) Class C12N 15/79 (20130101) C12N 15/81 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 13/22 (20130101) C12P 17/12 (20130101) Enzymes C12Y 114/16002 (20130101) C12Y 401/01028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519529 | Wright et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | QuesTek Innovations LLC (Evanston, Illinois) |
| ASSIGNEE(S) | QUESTEK INNOVATIONS LLC (Evanston, Illinois) |
| INVENTOR(S) | James A. Wright (Los Gatos, California); Weiming Huang (State College, Pennsylvania); Abhijeet Misra (Mountain View, California); Jeremy Hoishun Li (Sunnyvale, California); Jiadong Gong (Evanston, Illinois); Dana J. Frankel (Chicago, Illinois) |
| ABSTRACT | An alloy includes, in weight percentage, about 20.0% to about 25.0% chromium, 0% to about 5.0% molybdenum, about 3.0% to about 15.0% cobalt, about 1.5% to about 6.0% niobium, about 1.0% to about 3.0% tantalum, about 1.0% to about 5.0% tungsten, 0% to about 1.0% aluminum, 0% to about 0.05% carbon, 0% to about 0.01% titanium, and the balance nickel and incidental elements and impurities, wherein the alloy includes L12 and D022 precipitates in a compact morphology. |
| FILED | Thursday, November 20, 2014 |
| APPL NO | 14/548488 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 1/023 (20130101) C22C 19/055 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/10 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 21/087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519569 | Parker et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Kevin Kit Parker (Cambridge, Massachusetts); Grant Michael Gonzalez (Thousand Oaks, California); Holly M. Golecki (Acton, Massachusetts); Kwanwoo Shin (Lexington, Massachusetts); Josue Adrian Goss (Somerville, Massachusetts) |
| ABSTRACT | Exemplary embodiments provide systems, devices and methods for the fabrication of three-dimensional polymeric fibers having micron, submicron and nanometer dimensions, as well as methods of use of the polymeric fibers. |
| FILED | Thursday, February 13, 2014 |
| APPL NO | 14/763620 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 2377/10 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/06 (20130101) D01D 5/18 (20130101) Original (OR) Class Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/605 (20130101) D01F 9/00 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/021 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249921 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520444 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Po-Jung Huang (College Station, Texas); Gerard L. Coté (College Station, Texas); Mitchell B. Robinson (Willow Park, Texas); Jun Kameoka (College Station, Texas); Haley L. Marks (Brighton, Massachusetts) |
| ABSTRACT | There is a need in the point-of-care diagnostic community for an efficient and portable method for testing blood and other biological fluids that can be easily translated across multiple applications. An aspect of the invention described involves monitoring the optical properties of molecularly-mediated nanoparticle assemblies though an optically transparent and magnetically active microfluidic chip, which has recently emerged as an attractive method for biomarker detection as it is an efficient tool for monitoring the binding events that take place in a sensing assay. In one embodiment, this device is directed towards two-nanoparticle assays that rely on the assembly or disassembly of plasmonic and magnetic nanoparticles in response to a certain analyte. A further embodiment is directed to a spiral microfluidic using inertial forces to filter fluid components by size, connected to a magnetically active channel comprised of a nickel micropad array, optically transparent microchannel, and permanent magnets. |
| FILED | Wednesday, May 09, 2018 |
| APPL NO | 15/975313 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) B01L 2300/088 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 21/658 (20130101) Original (OR) Class G01N 33/553 (20130101) G01N 33/54326 (20130101) G01N 33/54346 (20130101) G01N 33/54366 (20130101) G01N 2001/4088 (20130101) G01N 2021/651 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520975 | Lilja et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | David J. Lilja (Maplewood, Minnesota); Mohammadhassan Najafi (Minneapolis, Minnesota); Marcus Riedel (Minneapolis, Minnesota); Kiarash Bazargan (Plymouth, Minnesota) |
| ABSTRACT | In some examples, a device includes an integrated circuit and two or more computational units configured to process respective stochastic bit streams in accordance with respective input clocks. Each of the stochastic bit streams comprises sequential sets of data bits, each of the sets of data bits representing a numerical value based on a probability that any bit in the respective set of data bits is one. The respective input clocks for each of the two or more computational units are unsynchronized. |
| FILED | Friday, March 03, 2017 |
| APPL NO | 15/448997 |
| ART UNIT | 2187 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/12 (20130101) Original (OR) Class G06F 7/70 (20130101) Image Data Processing or Generation, in General G06T 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522169 | Tanner et al. |
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| FUNDED BY |
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| APPLICANT(S) | San Francisco State University (Long Beach, California) |
| ASSIGNEE(S) | TRUSTEES OF THE CALIFORNIA STATE UNIVERSITY (Long Beach, California) |
| INVENTOR(S) | Kimberly Tanner (San Francisco, California); Melinda T. Owens (San Mateo, California); Jeffrey Schinske (San Francisco, California); Mike Wong (San Francisco, California); Shannon Seidel (Tacoma, Washington) |
| ABSTRACT | A system is provided to determine teaching technique based upon sound amplitude comprising: processor; and a memory device holding an instruction set executable on the processor to cause the computer system to perform operations comprising: sampling amplitude of sound at a sampling rate; assigning a respective sound amplitude and a respective amplitude variation to the respective sound sample; and classifying the sound samples based upon the assigned sound amplitude and sound sample variation. |
| FILED | Friday, September 08, 2017 |
| APPL NO | 15/699794 |
| ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/00 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 21/10 (20130101) G10L 25/21 (20130101) G10L 25/48 (20130101) G10L 25/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522326 | Walsh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael Patrick Walsh (Somerville, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | A method of locating a substrate within a field of view of an imaging system includes acquiring an image of a first marker on a substrate in the field of view. The first marker has a first spatial pattern representing a position of the first marker relative to the substrate. The method also includes determining possible positions of the substrate based on the first spatial pattern and moving the substrate relative to the field of view based on the possible positions of the substrate. The method also includes acquiring an image of a second marker on the substrate in the field of view. The second marker has a second pattern representing a position of the second marker relative to the substrate. The method further includes determining the position of the substrate relative to the field of view based on the position of the second marker on the substrate. |
| FILED | Wednesday, February 14, 2018 |
| APPL NO | 15/896377 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) Optical Elements, Systems, or Apparatus G02B 21/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/28 (20130101) Original (OR) Class H01J 37/222 (20130101) H01J 37/3023 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/68 (20130101) H01L 23/544 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522842 | Qi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Ming Qi (Knoxville, Tennessee); Thomas Zawodzinski (Knoxville, Tennessee); Shane Foister (Knoxville, Tennessee) |
| ABSTRACT | A catalyst is provided for the two electron reduction of oxygen. The catalyst can be reversible or near-reversible. The catalyst comprises a gold and a cobalt coordination complex, i.e., N,N′-bis(salicylidene)ethylene-diaminocobalt (II) (cobalt salen) or a derivative thereof. The cobalt coordination complex can be polymerized to form a film, for example, via electropolymerization, to cover a gold surface. Also provided are metal-air batteries, fuel cells, and air electrodes that comprise the catalyst, as well as methods of using the catalyst, for example, to reduce oxygen and/or produce hydrogen peroxide. |
| FILED | Monday, November 03, 2014 |
| APPL NO | 15/033349 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/88 (20130101) H01M 4/90 (20130101) H01M 4/92 (20130101) H01M 4/8615 (20130101) H01M 4/8626 (20130101) H01M 4/8647 (20130101) H01M 4/8652 (20130101) H01M 4/8657 (20130101) H01M 4/8871 (20130101) H01M 4/8892 (20130101) H01M 4/9008 (20130101) Original (OR) Class H01M 4/9041 (20130101) H01M 4/9075 (20130101) H01M 12/02 (20130101) H01M 12/06 (20130101) H01M 12/08 (20130101) H01M 12/085 (20130101) H01M 2004/021 (20130101) H01M 2300/0014 (20130101) H01M 2300/0068 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522884 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| INVENTOR(S) | Yan Wang (Worcester, Massachusetts); Eric Gratz (Worcester, Massachusetts); Qina Sa (Worcester, Massachusetts); Zhangfeng Zheng (Worcester, Massachusetts); Joseph Heelan (Worcester, Massachusetts) |
| ABSTRACT | Cathode material from exhausted lithium ion batteries are dissolved in a solution for extracting the useful elements Co (cobalt), Ni (nickel), Al (Aluminum) and Mn (manganese) to produce active cathode materials for new batteries. The solution includes compounds of desirable materials such as cobalt, nickel, aluminum and manganese dissolved as compounds from the exhausted cathode material of spent cells. Depending on a desired proportion, or ratio, of the desired materials, raw materials are added to the solution to achieve the desired ratio of the commingled compounds for the recycled cathode material for new cells. The desired materials precipitate out of solution without extensive heating or separation of the desired materials into individual compounds or elements. The resulting active cathode material has the predetermined ratio for use in new cells, and avoids high heat typically required to separate the useful elements because the desired materials remain commingled in solution. |
| FILED | Tuesday, November 22, 2016 |
| APPL NO | 15/358862 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/40 (20130101) C01G 53/50 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/02 (20130101) C22B 7/006 (20130101) C22B 26/12 (20130101) C22B 47/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 10/54 (20130101) Original (OR) Class H01M 10/0525 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/234 (20151101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/84 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10523488 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Jia-Chin Lin (Taoyuan, Taiwan); Yu-Ting Sun (Taoyuan, Taiwan); Harold Vincent Poor (Princeton, New Jersey) |
| ABSTRACT | A system and method for performing initial synchronization during wireless sector searches. The system includes a first subsystem for coarse timing alignment including a decimator to reduce computational complexity and a long-lag differential correlator, a second subsystem for jointly estimating RTE and FFO utilizing a short-lag differential correlator, and a third subsystem for jointly detecting IFO and SID utilizing segmental FD MFs. The system and method of the present disclosure accounts for intercell interference, ICI, and multipath fading with assistance from inherent diversity. |
| FILED | Monday, December 19, 2016 |
| APPL NO | 15/383588 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0032 (20130101) H04L 27/2659 (20130101) Original (OR) Class H04L 27/2688 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10523777 | Yeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | NORTHEASTERN UNIVERSITY (Boston, Massachusetts); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Edmund Meng Yeh (Newton, Massachusetts); Ying Cui (Shaanxi, China PRC); Ran Liu (Heilongjiang, China PRC); Tracey Ho (Pasadena, California); Michael Burd (Lees Summit, Missouri); Derek Leong (Singapore, Singapore) |
| ABSTRACT | A system and method for joint dynamic interest request forwarding and dynamic cache placement and eviction and provided within the context of the Named Data Networking (NDN) architecture. The system and method employ a virtual control plane that operates on the user demand rate for data objects in the network, and an actual plane that handles Interest Packets and Data Packets. Distributed algorithms within the virtual plane achieve network load balancing through dynamic forwarding and caching, thereby maximizing the user demand rate that the NDN network can satisfy. A method of congestion control is also provided to achieve optimal network fairness using the VIP framework. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 15/022251 |
| ART UNIT | 2449 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/02 (20130101) H04L 45/64 (20130101) H04L 45/586 (20130101) H04L 47/27 (20130101) H04L 67/2842 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524344 | Milchberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Howard M. Milchberg (Potomac, Maryland); Andrew Goers (Adelphi, Maryland); George Hine (College Park, Maryland); Fatholah Salehi (Hyattsville, Maryland); Linus Feder (Washington, District of Columbia); Bo Miao (College Park, Maryland) |
| ABSTRACT | A laser-plasma-based acceleration system includes a focusing element and a laser pulse emission directing a laser beam to the focusing element to such that laser pulses transform into a focused beam and a chamber defining a nozzle having a throat and an exit orifice, emitting a critical density range gas jet from the exit orifice for laser wavelengths ranging from ultraviolet to the mid-infrared. the critical density range gas jet intersects the focused beam at an angle and in proximity to the exit orifice of the nozzle to define a point of intersection between the focused beam and the critical density range gas jet. In intersection with the critical density range gas jet, the pulsed focused beam drives a laser plasma wakefield relativistic electron beam. A corresponding method of laser-plasma-based acceleration is also described. The critical density range may include 2×1020 cm−3 to 5×1021 cm−3. |
| FILED | Monday, May 15, 2017 |
| APPL NO | 15/595675 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/003 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 35/00 (20130101) X-ray Technique H05G 2/003 (20130101) H05G 2/008 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10518330 | Huber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Dale L. Huber (Albuquerque, New Mexico); John Daniel Watt (Albuquerque, New Mexico); Jonathan Chavez (Grovetown, Georgia); Lauren Marie Ammerman (Albuquerque, New Mexico) |
| ABSTRACT | A method for creating nanoparticles directly from bulk metal by applying ultrasound to the surface in the presence of a two-part surfactant system. Implosive collapse of cavitation bubbles near the bulk metal surface generates powerful microjets, leading to material ejection. This liberated material is captured and stabilized by a surfactant bilayer in the form of nanoparticles. Nanoparticles can be produced regardless of the bulk metal form factor. The method is generally applicable of metals and alloys. The method can be applied to an environmentally important problem, the reclamation of gold from an electronic waste stream. |
| FILED | Thursday, December 13, 2018 |
| APPL NO | 16/219482 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0044 (20130101) B22F 9/04 (20130101) Original (OR) Class B22F 9/04 (20130101) B22F 9/16 (20130101) B22F 9/20 (20130101) B22F 9/20 (20130101) B22F 2009/001 (20130101) B22F 2202/01 (20130101) B22F 2202/01 (20130101) B22F 2301/255 (20130101) B22F 2304/054 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10518331 | Mirkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Matthew R. Jones (LaMesa, California); Matthew N. O'Brien (Plymouth, Minnesota) |
| ABSTRACT | Methods of synthesizing various metal nanoparticle structures having high uniformity, using iterative reduction and oxidation conditions, is provided herein. |
| FILED | Monday, July 13, 2015 |
| APPL NO | 15/324283 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0048 (20130101) B22F 9/24 (20130101) Original (OR) Class B22F 2001/0033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10518977 | Schneider et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Natel Energy, Inc. (Alameda, California) |
| ASSIGNEE(S) | Natel Energy, Inc. (Alameda, California) |
| INVENTOR(S) | Abraham D. Schneider (San Francisco, California); Erick M. Davidson (Oakland, California) |
| ABSTRACT | Disclosed herein is a belt assembly including a flexible belt with an improved belt attachment. The belt attachment includes two crossbars spaced along the length of the belt. The crossbars retain bearings that allow predetermined movement in six degrees of freedom. The crossbars are connected by a rigid body that attaches to the bearings. Implements that are attached to the rigid body are simply supported but restrained in pitching rotation. |
| FILED | Monday, March 05, 2018 |
| APPL NO | 15/912064 |
| ART UNIT | 3651 — Material and Article Handling |
| CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 15/52 (20130101) B65G 17/12 (20130101) B65G 17/14 (20130101) B65G 17/30 (20130101) B65G 17/36 (20130101) B65G 17/42 (20130101) Original (OR) Class B65G 17/126 (20130101) B65G 37/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519160 | Van de Bittner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Genevieve Van de Bittner (Stoneham, Massachusetts); Jacob M. Hooker (Belmont, Massachusetts) |
| ABSTRACT | Provided herein are radiolabeled compounds useful for non-invasive imaging techniques. An exemplary radiolabeled compound provided herein is useful as a radiotracer for positron emission tomography. The present application also provides unlabeled compounds useful in methods of treating diseases of the central nervous system or disease of the peripheral nervous system. Methods for preparing radiolabeled compounds, preparing unlabeled compounds, and diagnostic methods using labeled or unlabeled compounds are also provided. |
| FILED | Friday, July 17, 2015 |
| APPL NO | 15/326890 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0459 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) C07B 2200/05 (20130101) Heterocyclic Compounds C07D 473/16 (20130101) C07D 473/34 (20130101) C07D 473/40 (20130101) Original (OR) Class C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519580 | Fong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hao Fong (Pierre, South Dakota); Lifeng Zhang (Pierre, South Dakota); Yong Zhao (Pierre, South Dakota); Zhengtao Zhu (Pierre, South Dakota) |
| ASSIGNEE(S) | South Dakota Board of Regents (Pierre, South Dakota) |
| INVENTOR(S) | Hao Fong (Pierre, South Dakota); Lifeng Zhang (Pierre, South Dakota); Yong Zhao (Pierre, South Dakota); Zhengtao Zhu (Pierre, South Dakota) |
| ABSTRACT | A method of synthesizing mechanically resilient titanium carbide (TiC) nanofibrous felts comprising continuous nanofibers or nano-ribbons with TiC crystallites embedded in carbon matrix, comprising: (a) electrospinning a spin dope for making precursor nanofibers with diameters less than 0.5 J.Lm; (b) overlaying the nanofibers to produce a nano-fibrous mat (felt); and then (c) heating the nano-felts first at a low temperature, and then at a high temperature for making electrospun continuous nanofibers or nano-ribbons with TiC crystallites embedded in carbon matrix; and (d) chlorinating the above electrospun nano-felts at an elevated temperature to remove titanium for producing carbide derived carbon (CDC) nano-fibrous felt with high specific surface areas. |
| FILED | Monday, November 24, 2014 |
| APPL NO | 14/551348 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/921 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/16 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/634 (20130101) C04B 35/5611 (20130101) C04B 35/62277 (20130101) C04B 2235/77 (20130101) C04B 2235/80 (20130101) C04B 2235/422 (20130101) C04B 2235/425 (20130101) C04B 2235/441 (20130101) C04B 2235/781 (20130101) C04B 2235/3843 (20130101) C04B 2235/5264 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/728 (20130101) Original (OR) Class D04H 1/4209 (20130101) D04H 1/4382 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/14 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/36 (20130101) Technical Subjects Covered by Former US Classification Y10T 442/50 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519883 | Solomon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| INVENTOR(S) | Arun S. Solomon (Rochester Hills, Michigan); Kushal Narayanaswamy (Troy, Michigan); Gerald A. Szekely, Jr. (Sterling Heights, Michigan); David P. Sczomak (Troy, Michigan) |
| ABSTRACT | A catalyst temperature control system of a vehicle includes a fuel control module configured to control fuel injection based on a target air/fuel ratio that is fuel lean relative to a stoichiometric air/fuel ratio and a target fuel injection start timing. An exhaust gas recirculation (EGR) control module is configured to control an EGR valve based on a target EGR opening. An adjustment module is configured to, when a temperature of a catalyst in an exhaust system is less than a sum of a predetermined light-out temperature of the catalyst and a predetermined temperature and the target air/fuel ratio is fuel lean relative to the stoichiometric air/fuel ratio, based on a comparison of an engine speed and a predetermined engine speed, selectively adjust at least one of: a target throttle opening, a target spark timing, the target fuel injection start timing, the target air/fuel ratio, and the target EGR opening. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 15/995579 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/20 (20130101) F01N 9/00 (20130101) F01N 2900/1602 (20130101) Controlling Combustion Engines F02D 9/02 (20130101) F02D 13/0219 (20130101) F02D 41/0002 (20130101) F02D 41/30 (20130101) F02D 41/0065 (20130101) F02D 41/0235 (20130101) Original (OR) Class F02D 2009/0235 (20130101) F02D 2009/0276 (20130101) F02D 2200/101 (20130101) F02D 2200/0802 (20130101) F02D 2200/1002 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 26/47 (20160201) Ignition, Other Than Compression Ignition, for Internal-combustion Engines; Testing of Ignition Timing in Compression-ignition Engines F02P 5/1502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519923 | Momen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Ayyoub Mehdizadeh Momen (Knoxville, Tennessee); Kyle J. Gluesenkamp (Knoxville, Tennessee); Omar A. Abdelaziz (Knoxville, Tennessee); Edward A. Vineyard (Knoxville, Tennessee); Ahmed Abu-Heiba (Alexandria, Egypt); Adewale O. Odukomaiya (Powder Springs, Georgia) |
| ABSTRACT | Systems store energy mechanically at a first time and extract the energy at a later time. When excess electricity from renewable sources or during off-peak periods is available, a pump directs a working liquid (L) to pressurize a gas (G) that is confined within a pressure vessel. When electricity from renewable sources is not available or during periods of peak demand or pricing, the pressurized gas (G) directs the working liquid (L) through a hydropower turbine. The turbine drives a generator through a mechanical coupling to provide electricity for powering a load. In addition, the system can leverage (take) any waste heat as the input to boost the efficiency of the system. The described systems function at ground level and are modular and scalable in capacity. |
| FILED | Thursday, September 01, 2016 |
| APPL NO | 15/254137 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 7/00 (20130101) Machines or Engines for Liquids F03B 1/02 (20130101) Original (OR) Class F03B 13/06 (20130101) Wind Motors F03D 9/14 (20160501) Positive-displacement Machines for Liquids; Pumps F04B 41/02 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2220/706 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 15/006 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/22 (20130101) Y02E 10/725 (20130101) Y02E 60/15 (20130101) Y02E 60/17 (20130101) Y02E 70/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520194 | Berry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Jonathan Dwight Berry (Simpsonville, South Carolina); Michael John Hughes (State College, Pennsylvania) |
| ABSTRACT | The present disclosure is directed to a radially stacked fuel injection module for a segmented annular combustion system. The fuel injection module includes a bundled tube fuel nozzle portion and a plurality of fuel injection lances. In one instance, a first set of fuel injection lances and a second set of fuel injection lances share a housing with the bundled tube fuel nozzle. The first and second sets of fuel injection lances are radially stacked, each set of lances being in communication with a respective injector fuel plenum. The fuel injection lances deliver fuel to a respective premixing channel formed between the side walls of an integrated combustor nozzle, an aft end of which defines a turbine nozzle. In another instance, the bundled tube fuel nozzle may be provided as a radially inner fuel nozzle and a radially outer fuel nozzle, each with a respective bundled tube fuel plenum. |
| FILED | Tuesday, March 21, 2017 |
| APPL NO | 15/464411 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Burners F23D 14/62 (20130101) F23D 14/64 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/28 (20130101) Original (OR) Class F23R 3/34 (20130101) F23R 3/42 (20130101) F23R 3/286 (20130101) F23R 3/346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520252 | Momen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Ayyoub Mehdizadeh Momen (Knoxville, Tennessee); Kyle R. Gluesenkamp (Knoxville, Tennessee); Edward Allan Vineyard (Knoxville, Tennessee); Roger A. Kisner (Knoxville, Tennessee) |
| ABSTRACT | A dryer includes a plurality of piezoelectric transducers in electrical communication with a high frequency piezoelectric oscillation generator. The piezoelectric oscillation generator controls the duty cycle and resonant frequency source signal that drive the plurality of piezoelectric transducers non-continuously. The piezoelectric transducers dry the wet articles without heating air passing through the articles. |
| FILED | Monday, October 30, 2017 |
| APPL NO | 15/798057 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Laundering, Drying, Ironing, Pressing or Folding Textile Articles D06F 58/02 (20130101) D06F 58/20 (20130101) D06F 58/28 (20130101) Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 5/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520527 | Pan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Xiaoqing Pan (Irvine, California); Thomas F. Blum (Irvine, California); Mingjie Xu (Irvine, California); Jake Jokisaari (Ann Arbor, Michigan); Wilbur Bigelow (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure relates to in situ transmission electron microscope (TEM) holders with improved stability and electrical sensitivity. The holders feature a front bearing seal and a rear bearing seal which allow the holders to achieve high sensitivity, high stability, large range of motion and high vacuum isolation. The bearings use a PEEK insulating disk as a pivot point for translation and tilting motion, and use O-rings to dampen vibrations, provide electrical and vacuum insulation, and to set a grabbing force between the bearing and the probe. |
| FILED | Monday, December 17, 2018 |
| APPL NO | 16/221998 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/16 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 37/20 (20130101) H01J 37/244 (20130101) H01J 37/285 (20130101) H01J 2237/244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10521295 | Merl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Robert Bernard Merl (Los Alamos, New Mexico); Paul Stanley Graham (Los Alamos, New Mexico) |
| ABSTRACT | A radiation hardened single board computer (SBC) includes a processor; synchronous dynamic random-access memory (SDRAM); non-volatile memory; a field programmable gate array (FPGA); and board-level physical layer interfaces. |
| FILED | Monday, May 21, 2018 |
| APPL NO | 15/985536 |
| ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/206 (20130101) G06F 11/106 (20130101) Original (OR) Class G06F 11/0736 (20130101) G06F 11/1489 (20130101) G06F 13/4063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10521699 | Bremer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Peer-Timo Bremer (Livermore, California); Hyojin Kim (Livermore, California); Jayaraman J. Thiagarajan (Livermore, Washington) |
| ABSTRACT | A system for identifying objects in an image is provided. The system identifies segments of an image that may contain objects. For each segment, the system generates a segment score by inputting to a multi-scale neural network windows of multiple scales that include the segment that have been resampled to a fixed window size. A multi-scale neural network includes a feature extracting convolutional neural network (“feCNN”) for each scale and a classifier that inputs each feature of each feCNN. The segment score indicates whether the segment contains an object. The system generates a pixel score for pixels of the image. The pixel score for a pixel indicates that that pixel is within an object based on the segment scores of segments that contain that pixel. The system then identifies the object based on the pixel scores of neighboring pixels. |
| FILED | Thursday, October 12, 2017 |
| APPL NO | 15/782771 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/46 (20130101) G06K 9/2054 (20130101) G06K 9/6259 (20130101) Original (OR) Class G06K 9/6269 (20130101) G06K 9/6277 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/143 (20170101) G06T 2200/04 (20130101) G06T 2207/20021 (20130101) G06T 2207/20076 (20130101) G06T 2210/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522261 | DeGrado et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Timothy R. DeGrado (Rochester, Minnesota); Mukesh K. Pandey (Rochester, Minnesota); John Byrne (Boston, Massachusetts) |
| ABSTRACT | Methods of producing and isolating 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 13N, 52Mn, or 44Sc and solution targets for use in the methods are disclosed. The methods of producing 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 13N, 52Mn, or 44Sc include irradiating a closed target system with a proton beam. The closed target system can include a solution target. The methods of producing isolated 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61CU, 99mTC, 45-Ti, 52Mn, or 44Sc by ion exchange chromatography. An example solution target includes a target body including a target cavity for receiving the target material; a housing defining a passageway for directing a particle beam at the target cavity; a target window for covering an opening of the target cavity; and a coolant gas flow path disposed in the passageway upstream of the target window. |
| FILED | Friday, May 15, 2015 |
| APPL NO | 15/311052 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/08 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/22 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/001 (20130101) G21G 1/10 (20130101) Original (OR) Class G21G 2001/0021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522363 | Youtsey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MICROLINK DEVICES, INC. (Niles, Illinois) |
| ASSIGNEE(S) | MICROLINK DEVICES, INC. (Niles, Illinois) |
| INVENTOR(S) | Christopher Youtsey (Libertyville, Illinois); Robert McCarthy (Chicago, Illinois); Rekha Reddy (Chicago, Illinois) |
| ABSTRACT | Methods and systems for forming a device structure free of a substrate are described. Exemplary embodiments include a device structure comprising of device layers, a release layer, an etch stop layer, and a substrate. The device structure is exposed to photoenhanced wet etch environments to vertically and laterally etch the release layer to separate the device layers from the substrate. The device structure can include a contact layer, an etch stop layer, or both in some embodiments. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/044479 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/78 (20130101) H01L 21/0254 (20130101) H01L 21/02389 (20130101) H01L 21/02458 (20130101) H01L 21/02664 (20130101) H01L 21/7813 (20130101) H01L 21/30612 (20130101) Original (OR) Class H01L 21/30635 (20130101) H01L 21/67075 (20130101) H01L 21/67086 (20130101) H01L 29/2003 (20130101) H01L 31/02363 (20130101) H01L 33/22 (20130101) H01L 33/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522732 | Zaia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Edmond W. Zaia (Berkeley, California); Madeleine P. Gordon (Berkeley, California); Preston Zhou (Fremont, California); Boris Russ (Berkeley, California); Nelson Coates (Oakland, California); Ayaskanta Sahu (Berkeley, California); Jeffrey J. Urban (Emeryville, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Edmond W. Zaia (Berkeley, California); Madeleine P. Gordon (Berkeley, California); Preston Zhou (Fremont, California); Boris Russ (Berkeley, California); Nelson Coates (Oakland, California); Ayaskanta Sahu (Berkeley, California); Jeffrey J. Urban (Emeryville, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to thermoelectric polymer aerogels. In one aspect, a method includes depositing a solution on a substrate. The solution comprises a thermoelectric polymer. Solvent of the solution is removed to form a layer of the thermoelectric polymer. The layer is placed in a polar solvent to form a gel comprising the thermoelectric polymer. The gel is cooled to freeze the polar solvent. The gel is placed in a vacuum environment to sublimate the polar solvent from the gel to form an aerogel comprising the thermoelectric polymer. |
| FILED | Wednesday, April 19, 2017 |
| APPL NO | 15/491054 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/28 (20130101) C08J 9/0061 (20130101) C08J 2201/0484 (20130101) C08J 2205/022 (20130101) C08J 2325/18 (20130101) C08J 2425/18 (20130101) C08J 2465/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/24 (20130101) H01L 35/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522774 | Bush et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Kevin Alexander Bush (Stanford, California); Colin David Bailie (Menlo Park, California); Michael David McGehee (Palo Alto, California); Tomas Leijtens (Redwood City, California) |
| ABSTRACT | A buffer layer for protecting an organic layer during high-energy deposition of an electrically conductive layer is disclosed. Buffer layers in accordance with the present invention are particularly well suited for use in perovskite-based single-junction solar cells and double-junction solar cell structures that include at least one perovskite-based absorbing layer. In some embodiments, the buffer layer comprises a layer of oxide-based nanoparticles that is formed using solution-state processing, in which a solution comprising the nanoparticles and a volatile solvent is spin coated onto a structure that includes the organic layer. The solvent is subsequently removed in a low-temperature process that does not degrade the organic layer. |
| FILED | Friday, October 21, 2016 |
| APPL NO | 15/769287 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0725 (20130101) H01L 31/02167 (20130101) H01L 51/424 (20130101) H01L 51/442 (20130101) Original (OR) Class H01L 51/4233 (20130101) H01L 2251/303 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522827 | Young et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BASF Corporation (Florham Park, New Jersey) |
| ASSIGNEE(S) | BASF Corporation (Florham Park, New Jersey) |
| INVENTOR(S) | Kwo Young (Troy, Michigan); Tiejun Meng (Novi, Michigan); Michael A. Fetcenko (Rochester, Michigan) |
| ABSTRACT | Hydrogen storage negative electrodes based on group IV elements, for example hydrogen storage negative electrodes based on silicon and/or carbon, are highly effective towards reversibly charging/discharging hydrogen in an hydride electrochemical cell. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/142109 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/383 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 10/345 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522870 | Tan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | 24M Technologies, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | 24M Technologies, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Taison Tan (Pasadena, California); Yet-Ming Chiang (Weston, Massachusetts); Naoki Ota (Lexington, Massachusetts); Throop Wilder (Lincoln, Massachusetts); Mihai Duduta (Somerville, Massachusetts) |
| ABSTRACT | Embodiments described herein relate generally to devices, systems and methods of producing high energy density batteries having a semi-solid cathode that is thicker than the anode. An electrochemical cell can include a positive electrode current collector, a negative electrode current collector and an ion-permeable membrane disposed between the positive electrode current collector and the negative electrode current collector. The ion-permeable membrane is spaced a first distance from the positive electrode current collector and at least partially defines a positive electroactive zone. The ion-permeable membrane is spaced a second distance from the negative electrode current collector and at least partially defines a negative electroactive zone. The second distance is less than the first distance. A semi-solid cathode that includes a suspension of an active material and a conductive material in a non-aqueous liquid electrolyte is disposed in the positive electroactive zone, and an anode is disposed in the negative electroactive zone. |
| FILED | Tuesday, October 24, 2017 |
| APPL NO | 15/792052 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/38 (20130101) H01M 4/134 (20130101) H01M 4/362 (20130101) H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/483 (20130101) H01M 4/587 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) Original (OR) Class H01M 2004/021 (20130101) H01M 2004/023 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/54 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524344 | Milchberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Howard M. Milchberg (Potomac, Maryland); Andrew Goers (Adelphi, Maryland); George Hine (College Park, Maryland); Fatholah Salehi (Hyattsville, Maryland); Linus Feder (Washington, District of Columbia); Bo Miao (College Park, Maryland) |
| ABSTRACT | A laser-plasma-based acceleration system includes a focusing element and a laser pulse emission directing a laser beam to the focusing element to such that laser pulses transform into a focused beam and a chamber defining a nozzle having a throat and an exit orifice, emitting a critical density range gas jet from the exit orifice for laser wavelengths ranging from ultraviolet to the mid-infrared. the critical density range gas jet intersects the focused beam at an angle and in proximity to the exit orifice of the nozzle to define a point of intersection between the focused beam and the critical density range gas jet. In intersection with the critical density range gas jet, the pulsed focused beam drives a laser plasma wakefield relativistic electron beam. A corresponding method of laser-plasma-based acceleration is also described. The critical density range may include 2×1020 cm−3 to 5×1021 cm−3. |
| FILED | Monday, May 15, 2017 |
| APPL NO | 15/595675 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/003 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 35/00 (20130101) X-ray Technique H05G 2/003 (20130101) H05G 2/008 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10518934 | Close |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Donald R. Close (Fairfax, Virginia) |
| ABSTRACT | Embodiments of this disclosure include a rigid tray container and methods and equipment for using the rigid tray container in batched process operations. In one embodiment, a mass container is sized and dimensioned to receive one or several rigid tray containers. In other embodiments, equipment is configured to lid/unlid, secure, stack, load/unload, and buffer rigid tray containers. In other embodiments, equipment is configured to stack and stage mass containers. In some embodiments, methods are provided for batch processing items. |
| FILED | Tuesday, May 30, 2017 |
| APPL NO | 15/608646 |
| ART UNIT | 3651 — Material and Article Handling |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/005 (20130101) B07C 5/3412 (20130101) B07C 9/00 (20130101) Machines, Apparatus or Devices For, or Methods Of, Packaging Articles or Materials; Unpacking B65B 5/06 (20130101) B65B 57/02 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 1/46 (20130101) B65D 19/385 (20130101) B65D 21/045 (20130101) Original (OR) Class B65D 21/064 (20130101) B65D 21/0212 (20130101) B65D 21/0217 (20130101) B65D 21/0223 (20130101) B65D 25/205 (20130101) B65D 25/2808 (20130101) B65D 25/2888 (20130101) B65D 2203/02 (20130101) B65D 2203/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10521632 | Stephen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Victoria K. Stephen (Burke, Virginia); Elke Reuning-Elliott (Rosslyn, Virginia) |
| ABSTRACT | A distribution item includes a first item with a container having an outer surface defining an enclosed space. A computer-readable code is disposed on the outer surface. The computer-readable code is associated with a first level entity. The first item also includes destination information associated with a second level entity disposed on the outer surface. The distribution item also includes one or more second items removably positioned within the enclosed space of the first item. Each of the one or more second items includes the computer-readable code associated with the first level entity. |
| FILED | Thursday, February 02, 2017 |
| APPL NO | 15/423407 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/10 (20130101) B07C 3/14 (20130101) Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 5/025 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) G06K 7/1417 (20130101) G06K 7/10861 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0833 (20130101) Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus G07B 2017/00475 (20130101) G07B 2017/00588 (20130101) G07B 2017/00596 (20130101) G07B 2017/00709 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10521633 | Stephen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Victoria K. Stephen (Burke, Virginia); Elke Reuning-Elliott (Rosslyn, Virginia) |
| ABSTRACT | A multi-level distribution and tracking system is described. Processing equipment processes multi-level distribution items, the multi-level distribution items being associated with first, second, and third level entities. The multi-level distribution items include a computer readable code thereon. The processing equipment captures an image of the multi-level distribution item, reads a computer readable code associated with the first level entity, sender information for the second level entity, and destination address information for the third level entity. The processing equipment generates tracking information based on the processing of the multi-level distribution item, and can send the tracking information to the first level entity. |
| FILED | Wednesday, November 01, 2017 |
| APPL NO | 15/801092 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/10 (20130101) B07C 3/14 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) G06K 7/1417 (20130101) G06K 7/10861 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0833 (20130101) Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus G07B 2017/00475 (20130101) G07B 2017/00588 (20130101) G07B 2017/00596 (20130101) G07B 2017/00709 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10521755 | Yeager et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Teresa Y. Yeager (Washington, District of Columbia); Arneece L. Williams (Washington, District of Columbia); Neena Dhuria (Washington, District of Columbia) |
| ABSTRACT | A system and method for generating shipping labels for shipping items to other countries. The shipping label can be based on shipping information for the item. The shipping label can also contain information about whether there was a landed cost guarantee associated with the item. |
| FILED | Tuesday, May 03, 2016 |
| APPL NO | 15/145645 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0831 (20130101) Original (OR) Class G06Q 10/08345 (20130101) G06Q 50/28 (20130101) G06Q 50/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10521839 | Dearing et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Stephen M. Dearing (Herndon, Virginia); Carla F. Sherry (Annandale, Virginia) |
| ABSTRACT | This disclosure describes systems, methods and apparatus for finding and delivering a desired item, including unique or hard-to-find items. In one example, there is provided a method that includes receiving a request to find the item and broadcasting the request. The method includes receiving responses to the broadcasted request, the responses indicating a finding of the item and including a bid to sell the item. The method includes providing purchase options for the item to a source of the request based on the received responses, and receiving, from the source of the request, a selection of a purchase option from among the purchase options provided to the source. The method includes providing instructions to a provider of the selected purchase option based on the received selection. |
| FILED | Monday, April 06, 2015 |
| APPL NO | 14/679374 |
| ART UNIT | 3627 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/083 (20130101) G06Q 30/0601 (20130101) G06Q 30/0611 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D871713 | Mikolajczyk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Ryszard K. Mikolajczyk (Chicago, Illinois); Taurris D. Baskerville (Schaumburg, Illinois) |
| ABSTRACT | |
| FILED | Thursday, June 06, 2019 |
| APPL NO | 29/694044 |
| ART UNIT | 2912 — Design |
| CURRENT CPC | Miscellaneous D99/32 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10519857 | Johns et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Charles W. Johns (Brownsburg, Indiana); Emanuel Papandreas (Indianapolis, Indiana) |
| ABSTRACT | An assembly for a gas turbine engine is arranged to rotate about a central axis of the gas turbine engine. The assembly includes a disk formed to include a plurality of apertures. The disk is operable to transfer rotational energy. |
| FILED | Monday, October 24, 2016 |
| APPL NO | 15/332164 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/16 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/60 (20130101) F05D 2240/35 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/671 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520389 | Brandon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Jay Brandon (Poquoson, Virginia); Eugene A. Morelli (Williamsburg, Virginia) |
| ABSTRACT | Systems and methods are described for development of a nonlinear global aerodynamic model using fuzzy logic modeling as well as multivariate orthogonal function modeling with splines. The systems and methods described herein may be utilized to more quickly develop a global aerodynamic model of an aircraft, allowing for development of a global aerodynamic model of an aircraft in real-time, during a test flight, and reducing time and cost associated with the model development. |
| FILED | Friday, November 14, 2014 |
| APPL NO | 14/541732 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 9/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522891 | Drouin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Brian J. Drouin (Pasadena, California); Adrian Tang (Pasadena, California); Erich T. Schlecht (Pasadena, California) |
| ABSTRACT | A coupler for coupling electromagnetic radiation into a cavity, including a metal layer having a reflective surface and forming a ground plane; and one or more waveguides for gigahertz or terahertz electromagnetic radiation embedded in the metal layer. The waveguides each include two openings in the metal layer exposing a dielectric underneath; and a section of the metal layer between the two openings. A plurality of holes in the metal layer are disposed along a perimeter of the openings so as to shape the electric field of the electromagnetic radiation in a cavity coupled to the coupler. |
| FILED | Friday, August 03, 2018 |
| APPL NO | 16/054226 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) G01N 22/00 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/12 (20130101) H01P 3/121 (20130101) H01P 5/02 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 15/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524139 | Barsoum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use signal constellations which have unequally spaced (i.e. “geometrically spaced,” or “non-uniform”) points. In many embodiments, the transmitters and receivers use specific non-uniform quadrature amplitude modulation (NU-QAM) constellations. In a variety of embodiments, NU-QAM constellations are capacity optimized using a bit-interleaved coded modulation (BICM, also referred to as “parallel decode”) capacity measure. In a number of embodiments, the transmitters and receivers are described that use specific NU-QAM constellations that provide gains in BICM capacity relative to constellations that maximize the minimum distance between constellation points. |
| FILED | Monday, August 21, 2017 |
| APPL NO | 15/682512 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 5/006 (20130101) H04L 27/3405 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class H04W 72/0453 (20130101) H04W 72/0473 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524400 | Switzer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Steve Duane Switzer (St. Charles, Missouri); Brett Allen Hansen (Renton, Washington) |
| ABSTRACT | A component locating apparatus for alignment of components on opposite sides of a structural wall includes a source magnet and a clone magnet. The source magnet has a magnetic centroid positioned relative to a locating feature and is successively held against the first side of the structural wall at a plurality of spaced apart source positions. The clone magnet has a marking opening at a magnetic centroid and is magnetically held against the second side of the structural wall by an attractive magnetic force at clone positions corresponding to the source positions. The magnetic centroids are aligned by the attractive magnetic force and the marking opening allows an operator to mark the second side of the structural wall at the magnetic centroid of the clone magnet at each of the clone positions to mirror, on the second side, the source positions corresponding to the component locating template. |
| FILED | Monday, December 11, 2017 |
| APPL NO | 15/837126 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/12 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/021 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 13/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10519149 | Fuller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rodin Therapeutics, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Rodin Therapeutics, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathan Oliver Fuller (Arlington, Massachusetts); John A. Lowe, III (Stonington, Connecticut) |
| ABSTRACT | Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g., HDAC2). |
| FILED | Friday, March 23, 2018 |
| APPL NO | 15/934299 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10519494 | Hung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Combinati Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | COMBINATI INCORPORATED (Palo Alto, California) |
| INVENTOR(S) | Ju-Sung Hung (Palo Alto, California); Megan Dueck (Brisbane, California); Andrew Zayac (San Leandro, California) |
| ABSTRACT | The present disclose provides methods and systems for amplifying and quantifying nucleic acids and for detecting the presence or absence of a target in a sample. The methods and systems provided herein may utilize a device comprising a plurality of partitions separated from an external environment by a gas-permeable barrier. Certain methods disclosed herein involve subjecting nucleic acid molecules in the plurality of partitions to conditions sufficient to conduct nucleic acid amplification reactions. The nucleic acid molecules may be subjected to controlled heating in the plurality of partitions to generate data indicative of a melting point(s) of the nucleic acid molecules. |
| FILED | Thursday, May 09, 2019 |
| APPL NO | 16/408041 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2200/16 (20130101) B01L 2200/0684 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10520291 | Vasudevan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Srikanth Vasudevan (Shelton, Connecticut); Paul Suchy (Parma, Ohio); Matthew C. Birch (Madison, Alabama) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Srikanth Vasudevan (Shelton, Connecticut); Paul Suchy (Parma, Ohio); Matthew C. Birch (Madison, Alabama) |
| ABSTRACT | Methods involve using a guided munition (e.g., a mortar round or a grenade) that utilizes deployable flow effectors, activatable flow effectors and/or active flow control devices to extend the range and enhance the precision of traditional unguided munitions without increasing the charge needed for launch. Sensors such as accelerometers, magnetometers, IR sensors, rate gyros, and motor controller sensors feed signals into a controller which then actuates or deploys the flow effectors/flow control devices to achieve the enhanced characteristics. |
| FILED | Monday, March 05, 2018 |
| APPL NO | 15/911265 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/14 (20130101) F42B 10/44 (20130101) F42B 10/62 (20130101) F42B 15/01 (20130101) Original (OR) Class F42B 30/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10522903 | Parkins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Red Tail Hawk Corporation (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Red Tail Hawk Corporation (Philadelphia, Pennsylvania) |
| INVENTOR(S) | John W. Parkins (Philadelphia, Pennsylvania) |
| ABSTRACT | A magnetic field transmitter, especially a transmitter used in conjunction with wireless communications earplugs. In one embodiment, a plate of magnetic material is used behind a coil of electrical conductor to improve the efficiency of the transmitter and to provide electrical and magnetic shielding. The specific dimensions and characteristics of the preferred embodiment of the transmitter described herein provide for efficient wireless communications. |
| FILED | Friday, December 23, 2016 |
| APPL NO | 15/389973 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 11/08 (20130101) Antennas, i.e Radio Aerials H01Q 1/273 (20130101) Original (OR) Class H01Q 1/2291 (20130101) H01Q 7/06 (20130101) Transmission H04B 5/0006 (20130101) H04B 5/0075 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/1008 (20130101) H04R 1/1075 (20130101) H04R 1/1091 (20130101) H04R 25/554 (20130101) H04R 2209/022 (20130101) H04R 2420/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10519333 | Hladik |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brewer Science Inc. (Rolla, Missouri) |
| ASSIGNEE(S) | Brewer Science, Inc. (Rolla, Missouri) |
| INVENTOR(S) | Molly Hladik (Rolla, Missouri) |
| ABSTRACT | New carbon nanotube (CNT) compositions and methods of using those compositions are provided. Raw carbon nanotubes are mechanically dispersed via milling into multifunctional alcohols and mixtures of multifunctional alcohols and solvents to form pastes or dispersions that are viscous enough to be printed using standard means such as screen printing. These pastes or dispersions are stable in both dilute and concentrated solution. The invention allows films to be formed on substrates (e.g., plastics, glass, metals, ceramics). |
| FILED | Thursday, April 25, 2013 |
| APPL NO | 13/870497 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/52 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/31786 (20150401) Y10T 428/31993 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
| US 10519028 | Burris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISYS Technology Foundation, Inc. (Madison, Wisconsin) |
| ASSIGNEE(S) | WiSys Technology Foundation, Inc. (Madison, Wisconsin) |
| INVENTOR(S) | Shanna Arline Burris (North St. Paul, Minnesota); Dean Ivan Olson (River Falls, Wisconsin) |
| ABSTRACT | A lift system includes a block and tackle pulley system movable along a track and carrying first and second hooks at a common attachment axis. The first hook is attached at a front end of the saddle while the second hook is attached to the back end of the saddle. Once the saddle is lowered onto the horse the inward tension of the hooks caused by the weight of the saddle is released allowing the hooks to be removed from the saddle without human intervention. The lift system accommodates a range of saddle sizes and weights. |
| FILED | Friday, August 04, 2017 |
| APPL NO | 15/669240 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 71/00 (20130101) A63B 2244/24 (20130101) Saddles; Stirrups B68C 1/00 (20130101) B68C 1/002 (20130101) Original (OR) Class Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 11/046 (20130101) F16M 11/425 (20130101) F16M 11/2092 (20130101) F16M 13/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10520610 | Lam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CapeSym, Inc. (Natick, Massachusetts) |
| ASSIGNEE(S) | CapeSym, Inc. (Natick, Massachusetts) |
| INVENTOR(S) | Stephanie Lam (Newton, Massachusetts); John C. Fiala (Natick, Massachusetts); Shariar Motakef (Weston, Massachusetts) |
| ABSTRACT | A composite scintillator includes a matrix material and pieces of at least one scintillator material embedded in the matrix material. The scintillator material is (a) inorganic single-crystalline or ceramic, (b) organic plastic, or (c) glassy; and the embedded scintillator material scintillates in response to at least one of gamma-ray and neutron irradiation. |
| FILED | Thursday, December 14, 2017 |
| APPL NO | 15/841636 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/2002 (20130101) G01T 1/2008 (20130101) G01T 1/2018 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10519782 | Clum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Carey Clum (East Hartford, Connecticut); Evan P. Molony (Farmington, Connecticut); Charles Thistle (Middletown, Connecticut); Dominic J. Mongillo (West Hartford, Connecticut) |
| ABSTRACT | Airfoils having a body with leading and trailing edges and a first serpentine cavity within the body enabling a cooling flow in a first direction within the airfoil body, a second serpentine cavity fluidly connected to the first serpentine cavity enabling a cooling flow in a second direction, and a third serpentine cavity fluidly connected to the second serpentine cavity enabling a cooling flow in at least one of the first direction or a third direction. A resupply cavity is fluidly connected to the third serpentine cavity to supply a resupply air to the third serpentine cavity, a junction at the location of the second serpentine cavity, the resupply cavity and the third serpentine cavity, and a flow control feature arranged to turn the serpentine cooling air from the second direction and/or prevent resupply air backflow. |
| FILED | Sunday, June 04, 2017 |
| APPL NO | 15/613255 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Foundry Moulding B22C 9/24 (20130101) B22C 9/103 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/081 (20130101) F01D 5/187 (20130101) Original (OR) Class F01D 9/041 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/211 (20130101) F05D 2250/185 (20130101) F05D 2260/202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10522736 | Zeng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Changchun Zeng (Tallahassee, Florida); Yan Li (Tallahassee, Florida) |
| ABSTRACT | Thermally stable piezoelectric polymer foams (ferroelectrets) with high piezoelectric activity for sensing and actuation. The invention further includes a method of fabricating such foams in an environmentally friendly manner. |
| FILED | Friday, October 28, 2016 |
| APPL NO | 15/337660 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/08 (20130101) H01L 41/39 (20130101) H01L 41/45 (20130101) H01L 41/083 (20130101) H01L 41/193 (20130101) H01L 41/277 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 10520499 | Van de Water et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Judy Van de Water (Capay, California); Daniel Braunschweig (Davis, California) |
| ABSTRACT | The present invention provides diagnostic methods for determining the risk of developing an autism spectrum disorder (ASD) in a fetus or child by detecting in a biological sample from the mother antibodies that bind to one or more biomarkers selected from the group consisting of lactate dehydrogenase (LDH), guanine deaminase (GDA), collapsin response mediator protein 1 (CRMP1), stress-induced phosphoprotein 1 (STIP1), alpha subunit of the barbed-end actin binding protein Cap Z (CAPZA2), Y Box Binding Protein 1 (YBX1), eukaryotic translation and elongation factor 1A1 (EEF1A1), microtubule-associated protein Tau (MAPT), dihydropyrimidinase-like protein 2 (DPYSL2), dynamin 1-like protein (DNM1L), radixin (RDX), moesin (MSN), and ezrin (EZR). The invention further provides methods of preventing or reducing the risk of a fetus or child developing an ASD by administering to the mother an agent that blocks the binding of maternal antibodies to the one or more fetal biomarkers listed above or by removing from the mother antibodies that bind to the one or more fetal biomarkers. |
| FILED | Wednesday, November 16, 2016 |
| APPL NO | 15/353037 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/6896 (20130101) G01N 33/54313 (20130101) Original (OR) Class G01N 2800/28 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10521002 | Eastep et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
| ASSIGNEE(S) | INTEL CORPORATION (Santa Clara, California) |
| INVENTOR(S) | Jonathan M. Eastep (Portland, Oregon); Rohit Banerjee (Portland, Oregon); Richard J. Greco (West Lin, Oregon); Ilya Sharapov (San Jose, California); David N. Lombard (Rossmoor, California); Hari K. Nagpal (Southborough, Massachusetts) |
| ABSTRACT | Apparatus, systems, and methods provide dynamic spatial power steering among a plurality of power domains in the computer system on a per phase basis of a particular application. Dynamic spatial power steering may include, for example, determining a plurality of phases corresponding to an application comprising tasks for execution on a processing node. determining a spatial power distribution between a plurality of power domains on the processing node based on a performance metric for each phase, monitoring the application to detect a current phase, and applying the spatial power distribution correspond to the current phase to the plurality of power domains. |
| FILED | Thursday, October 19, 2017 |
| APPL NO | 15/788195 |
| ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/3206 (20130101) G06F 1/3234 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 10521728 | Lau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Troy M Lau (Stoneham, Massachusetts); Scott A Kuzdeba (Framingham, Massachusetts) |
| ABSTRACT | A method for predicting subject trustworthiness includes using at least one classifier to predict truthfulness of subject responses to prompts during a local or remote interview, based on subject responses and response times, as well as interviewer impressions and response times, and, in embodiments, also biometric measurements of the interviewer. Data from the subject interview is normalized and analyzed relative to an experience database previously created using data obtained from test subjects. Classifier prediction algorithms incorporate assumptions that subject response times are indicators of truthfulness, that subjects will tend to be consistently truthful or deceitful, and that conscious and subconscious impressions of the interviewer are predictive of subject trustworthiness. Data regarding interviewer impressions can be derived from interviewer response times, interviewer questionnaire answers, and/or interviewer biometric data. Appropriate actions based on trustworthiness predictions can include denial of security clearance or further investigation relevant to the subject. |
| FILED | Monday, April 04, 2016 |
| APPL NO | 15/089913 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/041 (20130101) Original (OR) Class G06N 7/005 (20130101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10518877 | Levien et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elwha LLC, a limited liability corporation of the State of Delaware (Bellevue, Washington) |
| ASSIGNEE(S) | Elwha LLC (Bellevue, Washington) |
| INVENTOR(S) | Royce A. Levien (Lexington, Massachusetts); Robert W. Lord (Seattle, Washington); Richard T. Lord (Tacoma, Washington); Mark A. Malamud (Seattle, Washington); John D. Rinaldo, Jr. (Bellevue, Washington); Lowell L. Wood, Jr. (Bellevue, Washington) |
| ABSTRACT | Disclosed herein are example embodiments for inter-vehicle communication for hazard handling with an unoccupied flying vehicle (UFV). For certain example embodiments, at least one machine may: (i) receive one or more flight attributes from a remote UFV, with the one or more flight attributes indicative of one or more flight characteristics of the remote UFV; or (ii) adjust a flight path of a UFV based at least partially on one or more flight attributes received from a remote UFV. However, claimed subject matter is not limited to any particular described embodiments, implementations, examples, or so forth. |
| FILED | Wednesday, December 19, 2012 |
| APPL NO | 13/720694 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Original (OR) Class B64C 2201/141 (20130101) B64C 2201/143 (20130101) B64C 2201/146 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/101 (20130101) Traffic Control Systems G08G 5/0069 (20130101) G08G 5/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10521549 | Ferguson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Richard J. Ferguson (Bealeton, Virginia); Joseph R. Marshall, Jr. (Manassas, Virginia); George A. Sawyer (Nashua, New Hampshire) |
| ABSTRACT | A method for providing a power estimation for an electronic system is disclosed. Initially, a system architecture of an electronic system design is initially developed, and the system architecture of the electronic system design is then converted to a power flow architecture of the electronic system design. For each power domain within the power flow architecture of the electronic system design, a power domain type is designated. Subsequently, power information are added to the power flow architecture of the electronic system. Finally, a power roll-up calculation is performed on the power flow architecture of the electronic system design in order to yield a final system power value for the electronic system design. |
| FILED | Thursday, September 06, 2018 |
| APPL NO | 16/123775 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3452 (20130101) G06F 17/5022 (20130101) G06F 17/5086 (20130101) Original (OR) Class G06F 2217/78 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10521883 | Hayes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Matthew John Francis Hayes (Prosper, Texas); Christopher J. Beardsley (Plano, Texas); David U. Fluckiger (Allen, Texas) |
| ABSTRACT | System and method for image turbulence correction includes: receiving a plurality of consecutive image frames; demosaicing previous, current and preceding image frames into a plurality of same size overlapping video tiles; determining a displacement of each of the video tiles; converting the video tiles of the current image frame, the previous image frame, and the plurality of preceding image frames into a frequency domain; iteratively processing the video tiles of the previous image frame, the current image frame and the plurality of preceding image frames for turbulence correction in the frequency domain; converting the turbulence corrected video tiles into a spatial domain, wherein the converted turbulence corrected video tiles form a single video frame tile including turbulence degradation correction; and mosaicing the single video frame tiles including turbulence degradation correction together to generate a full field of view turbulence correct video stream. |
| FILED | Thursday, July 26, 2018 |
| APPL NO | 16/046833 |
| ART UNIT | 2699 — Search and Capture Special Detail |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/4015 (20130101) Original (OR) Class G06T 5/10 (20130101) Pictorial Communication, e.g Television H04N 5/23229 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 31, 2019.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20191231.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page