FedInvent™ Patents
Patent Details for Tuesday, January 07, 2020
This page was updated on Monday, March 27, 2023 at 05:59 AM GMT
Department of Defense (DOD)
| US 10524493 | Feldman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Andrew B. Feldman (Columbia, Maryland); Jeffrey S. Lin (Silver Spring, Maryland); Kellogg Schwab (Bel Air, Maryland); Timothy Julian (Baltimore, Maryland); Christiane Wobus (Dexter, Michigan); David Weitz (Bolton, Massachusetts); John Heyman (Somerville, Massachusetts) |
| ABSTRACT | Food products and/or pharmaceutical preparations including (i) viral neutralizing antibodies or antibody fragments anchored to a probiotic microorganism and (ii) a carrier medium for delivering the viral neutralizing antibodies or antibody fragments anchored to probiotic microorganisms to the gut of a mammal. Also provided are methods of making food products and/or pharmaceutical preparations, which can be used to treat existing viral infections or prevent the spread or transmission of viral infection. |
| FILED | Tuesday, September 16, 2014 |
| APPL NO | 14/487592 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/135 (20160801) Original (OR) Class Indexing Scheme Relating to Lactic or Propionic Acid Bacteria Used in Foodstuffs or Food Preparation A23Y 2220/17 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Peptides C07K 16/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524707 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Zongxi Li (Cambridge, Massachusetts); Conor L. Evans (Charlestown, Massachusetts); Alexander J. Nichols (Cambridge, Massachusetts) |
| ABSTRACT | In one aspect, the present disclosure provides a system A system, including a light source, a detector, and a controller in electrical communication with the light source and the detector. The controller is configured to execute a program stored in the controller to trigger the light source to emit a first pulse of light having a first pulse duration for illumination of a target, actuate the detector after a first delay time following emission of the first pulse of light to begin detecting a first signal from the target for a first detection time, and repeat the steps of triggering the light source and actuating the detector at least once, varying for each repetition at least one of the first pulse duration, the first delay time, and the first detection time. |
| FILED | Monday, February 02, 2015 |
| APPL NO | 15/114951 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1477 (20130101) A61B 5/7475 (20130101) A61B 5/14556 (20130101) Original (OR) Class Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/00004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524733 | Siegel et al. |
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| FUNDED BY |
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| APPLICANT(S) | United States Army Research Laboratory ATTN:RDRL-LOC-I (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | David Siegel (Cincinnati, Ohio); Canh Ly (Laurel, Maryland); Troy Lau (Ann Arbor, Michigan); William D. Hairston (Churchville, Maryland) |
| ABSTRACT | A method for improving the signal to noise ratio of an EEG signal in which a wavelet packet decomposition having a plurality of levels is first applied to a time slice of the EEG signal. A default signal is set to the first wavelet packet and a default peak response is then calculated for the first wavelet node. An update signal is set to the default signal combined with another of the wavelet nodes and an update peak response signal is then calculated of the update signal. If the update peak response signal exceeds the default peak response, the default peak response is set equal to the update peak response and the default signal is set equal to the update signal. Otherwise, the value of the current node is set to zero which effectively eliminates the signal data of the current wavelet node. These steps are reiterated for all of the wavelet nodes and, thereafter, a composite waveform of the EEG signal is reconstructed from the non-zero wavelet nodes. |
| FILED | Monday, April 21, 2014 |
| APPL NO | 14/257110 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0476 (20130101) A61B 5/7203 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524762 | Kent |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Zackary J. Kent (Edwards, Colorado) |
| ABSTRACT | A phantom for simulating fetal heartbeat. The phantom includes a housing and a fetal heartbeat simulator. The housing has an exterior shaped like a female human pelvic region and surrounds an interior. The fetal heartbeat simulator includes a tube having a proximal end and a distal end, the distal end being positioned within the interior of the housing. The tube is filled with a first fluid having a first compressibility. A second fluid, having a compressibility that is greater than the compressibility of the first fluid, is disposed at the distal end of the tube. A pressure mechanism operably coupled to the proximal end of the tube is configured to selectively compress and decompress the first and second fluids. |
| FILED | Thursday, November 16, 2017 |
| APPL NO | 15/815000 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0444 (20130101) A61B 5/4362 (20130101) A61B 8/02 (20130101) A61B 8/587 (20130101) A61B 8/0866 (20130101) Original (OR) Class Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 23/281 (20130101) G09B 23/286 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524976 | Ross |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright Patterson AFB, Ohio) |
| INVENTOR(S) | Lewis Tyson Ross (Franklin, Ohio) |
| ABSTRACT | An intelligent compression device for controllable compression. The compression device includes a compressible body and a microprocessor. The compressible body encircles a limb of a user and includes an elastomer layer and an activation layer. The elastomer layer includes voxelated liquid crystal elastomers that contract in response to a stimulus. The activation element, which is positioned proximate to the elastomer layer, supplies the stimulus. The microprocessor actuates at least a portion of the activation element layer. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 15/493332 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 7/007 (20130101) A61H 9/0007 (20130101) A61H 11/00 (20130101) Original (OR) Class A61H 11/02 (20130101) A61H 36/00 (20130101) A61H 2011/005 (20130101) A61H 2201/10 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/169 (20130101) A61H 2201/0207 (20130101) A61H 2201/0228 (20130101) A61H 2201/501 (20130101) A61H 2201/1207 (20130101) A61H 2201/1635 (20130101) A61H 2201/1647 (20130101) A61H 2201/1697 (20130101) A61H 2201/5002 (20130101) A61H 2201/5015 (20130101) A61H 2201/5071 (20130101) A61H 2201/5082 (20130101) A61H 2201/5097 (20130101) A61H 2209/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525085 | Smith et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Douglas H. Smith (Boothwyn, Pennsylvania); Daniel Kacy Cullen (Media, Pennsylvania); John A. Wolf (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention relates to methods and compositions for maintaining the pro-regenerative capacity of distal nerve segments following nerve injury. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/863278 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525123 | Tomaka et al. |
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| FUNDED BY |
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| APPLICANT(S) | Janssen Vaccines and Prevention B.V. (Leiden, Netherlands); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland); THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Fort Detrick, Maryland) |
| ASSIGNEE(S) | Janssen Vaccines and Prevention B.V. (Leiden, Netherlands); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland); The Government of The United States, as represented by The Secretary Of The Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Frank Tomaka (Titusville, New Jersey); Maria Grazia Pau (Leiden, Netherlands); Johanna Schuitemaker (Amstelveen, Netherlands); Dan Barouch (Newton, Massachusetts); Jintanat Ananworanich (Rockville, Maryland); Merlin Robb (Silver Spring, Maryland); Nelson L. Michael (Silver Spring, Maryland); Jerome Kim (Silver Spring, Maryland) |
| ABSTRACT | Methods for inducing an immune response against Human Immunodeficiency Virus (HIV) in HIV-infected subjects undergoing antiretroviral therapy (ART) are described. The methods include administering an adenovirus vector primer vaccine and a modified vaccinia virus (MVA) vector booster vaccine encoding mosaic HIV antigens. |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 16/385062 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 2039/57 (20130101) A61K 2039/70 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2710/24043 (20130101) C12N 2710/24143 (20130101) C12N 2740/16021 (20130101) C12N 2740/16034 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) C12N 2740/16234 (20130101) C12N 2740/16271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525182 | Burbank et al. |
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| FUNDED BY |
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| APPLICANT(S) | NxStage Medical, Inc. (Lawrence, Massachusetts) |
| ASSIGNEE(S) | NxStage Medical, Inc. (Lawrence, Massachusetts) |
| INVENTOR(S) | Jeffrey H. Burbank (Boxford, Massachusetts); Dennis M. Treu (Castle Rock, Colorado); Daniel J. Rubery, Jr. (Windham, New Hampshire); Scott W. Newell (Ipswich, Massachusetts); James M. Brugger (Newburyport, Massachusetts); William J. Schnell (Libertyville, Illinois); William K. Weigel (York, Maine); Steve A. White (Hudson, Massachusetts); Mark T. Wyeth (Andover, Massachusetts); Jerome James (Vestavia, Alabama); David Desouza (Essex, Massachusetts); Joseph E. Turk, Jr. (North Andover, Massachusetts); Garrett Casey (Methuen, Massachusetts) |
| ABSTRACT | The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described. |
| FILED | Friday, October 09, 2015 |
| APPL NO | 15/517928 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/14 (20130101) A61M 1/34 (20130101) A61M 1/165 (20140204) A61M 1/341 (20140204) A61M 1/1605 (20140204) Original (OR) Class A61M 1/1613 (20140204) A61M 1/1615 (20140204) A61M 1/1647 (20140204) A61M 1/3403 (20140204) A61M 1/3434 (20140204) A61M 1/3437 (20140204) A61M 1/3441 (20130101) A61M 1/3444 (20140204) A61M 1/3448 (20140204) A61M 1/3607 (20140204) A61M 1/3609 (20140204) A61M 1/3635 (20140204) A61M 2205/15 (20130101) A61M 2205/058 (20130101) A61M 2205/502 (20130101) A61M 2205/702 (20130101) A61M 2205/3331 (20130101) A61M 2205/3334 (20130101) A61M 2205/3341 (20130101) A61M 2205/3351 (20130101) A61M 2205/3355 (20130101) A61M 2205/3365 (20130101) A61M 2205/3368 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525421 | Kolel-Veetil et al. |
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| FUNDED BY |
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| APPLICANT(S) | Manoj K. Kolel-Veetil (Alexandria, Virginia); Paul E. Sheehan (Springfield, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Manoj K. Kolel-Veetil (Alexandria, Virginia); Paul E. Sheehan (Springfield, Virginia) |
| ABSTRACT | An article having a nanoporous membrane and a nanoporous graphene sheet layered on the nanoporous membrane. A method of: depositing a layer of a diblock copolymer onto a graphene sheet, and etching a minor phase of the diblock copolymer and a portion of the graphene in contact with the minor phase to form a nanoporous article having a nanoporous graphene sheet and a nanoporous layer of a polymer. A method of: depositing a hexaiodo-substituted macrocycle onto a substrate having a Ag(111) surface; coupling the macrocycle to form a nanoporous graphene sheet; layering the graphene sheet and substrate onto a nanoporous membrane with the graphene sheet in contact with the nanoporous membrane; and etching away the substrate. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/207912 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 69/148 (20130101) B01D 71/021 (20130101) B01D 71/44 (20130101) Original (OR) Class B01D 2053/221 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/442 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525472 | Pandey et al. |
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| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Santosh Pandey (Ames, Iowa); Riley Brien (Ann Arbor, Michigan); Taejoon Kong (Ames, Iowa); Zach Njus (Ames, Iowa); Jared Anderson (Cedar Rapids, Iowa) |
| ABSTRACT | Apparatus, methods, and systems for automated liquid droplet manipulation include an open droplet supporting surface. An actuator can translate the surface in space with at least one degree freedom of movement to influence movement of one or more droplets on the surface. In one embodiment, the surface is patterned with areas that attract the droplets and interstitial areas that repel the droplets to enhance transport of droplets. For example, for water-based droplets the attracting areas can be hydrophilic and the repelling hydrophobic. In one embodiment, the repelling areas are superhydrophobic. Electromechanical movement of the surface avoids expensive and complex microfluidic fabrication and components, and avoids electrowetting requirements. |
| FILED | Wednesday, April 27, 2016 |
| APPL NO | 15/140182 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502792 (20130101) Original (OR) Class B01L 2200/14 (20130101) B01L 2200/0605 (20130101) B01L 2300/123 (20130101) B01L 2300/126 (20130101) B01L 2300/165 (20130101) B01L 2300/166 (20130101) B01L 2400/0457 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526049 | Helton |
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| FUNDED BY |
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| APPLICANT(S) | Justin R. Helton (Fredericksburg, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Justin R. Helton (Fredericksburg, Virginia) |
| ABSTRACT | A lift assist mechanism is provided for positioning a hatch cover in relation to a corresponding opening in a hatch frame. The assist mechanism includes a torsion bar and a lifting mechanism. The torsion bar has first and second opposite ends. The first end secures to the hatch frame. The second end connects to a bar spur gear. The lifting assembly includes a lift spur gear and a hinge gear. The lift spur gear engages the bar spur gear. The gears convert an acute angle twist of the bar to substantially perpendicular pivot the hatch cover from the hatch frame. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/149548 |
| ART UNIT | 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 19/00 (20130101) B63B 19/14 (20130101) B63B 19/24 (20130101) Original (OR) Class B63B 19/28 (20130101) B63B 2019/0069 (20130101) Gearing F16H 19/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526077 | Wulff et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Ole Wulff (Ansonia, Connecticut); Derek Geiger (Wilton, Connecticut) |
| ABSTRACT | A flight system for an aircraft and method for controlling a clearance between a first rotor disk and a second rotor disk of an aircraft is disclosed. The flight system includes a sensor for measuring an angle of deviation of at least one of a first rotor disk and a second rotor disk of the aircraft to indicate a clearance between the first rotor disk and the second rotor disk as well as sensors for measuring a flight condition of the aircraft. A control allocation module uses the measured angle of deviation and the flight condition of the aircraft to determine an allocation of control settings to axis-controlling devices of the aircraft to attain a selected pitch of the aircraft, wherein the allocation is based at least on the measured angle of deviation and the flight state of the aircraft. |
| FILED | Friday, February 24, 2017 |
| APPL NO | 15/441506 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/008 (20130101) Original (OR) Class B64C 27/10 (20130101) B64C 27/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526091 | Beckman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Mary Eileen Beckman (West Chester, Pennsylvania); Mark Steven Kuehn (Gilbert, Arizona); Robert Herkimer (Savannah, Georgia) |
| ABSTRACT | A system for cooling a plurality of electrical equipment components inside a mobile platform may include at least one manifold and a plurality of flexible tubing ducts. The manifold may have an outlet, and a plurality of inlet tubing connections in fluid communication with the outlet. The outlet may be coupled to an interface of a cooling system of the platform by exhaust tubing. Each of the flexible tubing ducts may have a proximal end and a distal end. Each proximal end may be selectively connectable to the inlet tubing connections. Each distal end may have an air intake port that is alternatively positionable in two or more thermal dissipation zones of the electrical equipment components for permitting an exhaust profile inside the platform to the interface to be reconfigured based at least in part on respective positions of the electrical equipment components. |
| FILED | Wednesday, December 03, 2014 |
| APPL NO | 14/559875 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles B60H 1/00564 (20130101) B60H 2001/00614 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 13/08 (20130101) Original (OR) Class B64D 47/00 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/2059 (20130101) H05K 7/20572 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526280 | Wipf et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Peter Wipf (Pittsburgh, Pennsylvania); Athanassios Tzounopoulos (Pittsburgh, Pennsylvania) |
| ABSTRACT | A compound, or pharmaceutically acceptable salt thereof, having a formula I of: wherein R1 is H or optionally-substituted alkyl; R2 is optionally-substituted alkyl; R3 and R4 are each independently H or optionally-substituted alkyl; R5 is H, optionally-substituted alkyl, acyl, or alkoxycarbonyl; R6 and R7 are each independently H, deuterium, optionally-substituted alkyl, or R6 and R7 together form a carbocyclic; R8 is optionally-substituted thiazolyl, optionally-substituted thiophenyl, or substituted phenyl, provided that if R8 is 4-halophenyl, then R2 is substituted alkyl or branched alkyl or at least one of R6 or R7 is not H; and R30, R31 and R32 are each independently H, deuterium, halogen, substituted sulfanyl, or optionally-substituted alkoxy. |
| FILED | Friday, November 13, 2015 |
| APPL NO | 15/526668 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 25/00 (20180101) A61P 25/28 (20180101) A61P 27/16 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 271/28 (20130101) Original (OR) Class C07C 323/33 (20130101) Heterocyclic Compounds C07D 277/28 (20130101) C07D 305/06 (20130101) C07D 333/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526289 | Silverman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Richard B. Silverman (Winnetka, Illinois); Yinan Zhang (Lexington, Kentucky) |
| ABSTRACT | The present invention relates to the identification of compounds and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the provided compounds. |
| FILED | Tuesday, August 22, 2017 |
| APPL NO | 15/683131 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Heterocyclic Compounds C07D 231/18 (20130101) Original (OR) Class C07D 231/20 (20130101) C07D 401/06 (20130101) C07D 403/06 (20130101) C07D 471/04 (20130101) C07D 498/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526399 | Ingber et al. |
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| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Donald E. Ingber (Boston, Massachusetts); Michael Super (Lexington, Massachusetts); Jeffrey Charles Way (Cambridge, Massachusetts); Mark J. Cartwright (West Newton, Massachusetts); Julia B. Berthet (Brookline, Massachusetts); Dinah R. Super (Lexington, Massachusetts); Martin Rottman (Cambridge, Massachusetts); Alexander L. Watters (Melrose, Massachusetts) |
| ABSTRACT | Described herein are engineered microbe-targeting or microbe-binding molecules, kits comprising the same and uses thereof. Some particular embodiments of the microbe-targeting or microbe-binding molecules comprise a carbohydrate recognition domain of mannose-binding lectin, or a fragment thereof, linked to a portion of a Fc region. In some embodiments, the microbe-targeting molecules or microbe-binding molecules can be conjugated to a substrate, e.g., a magnetic microbead, forming a microbe-targeting substrate (e.g., a microbe-targeting magnetic microbead). Such microbe-targeting molecules and/or substrates and the kits comprising the same can bind and/or capture of a microbe and/or microbial matter thereof, and can thus be used in various applications, e.g., diagnosis and/or treatment of an infection caused by microbes such as sepsis in a subject or any environmental surface. Microbe-targeting molecules and/or substrates can be regenerated after use by washing with a low pH buffer or buffer in which calcium is insoluble. |
| FILED | Wednesday, January 25, 2017 |
| APPL NO | 15/415352 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/68 (20170801) A61K 47/6815 (20170801) Peptides C07K 14/42 (20130101) C07K 16/12 (20130101) Original (OR) Class C07K 2319/33 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54353 (20130101) G01N 33/56911 (20130101) G01N 33/56916 (20130101) G01N 33/56938 (20130101) G01N 33/56961 (20130101) G01N 2333/42 (20130101) G01N 2333/4724 (20130101) Technologies for Adaptation to Climate Change Y02A 50/53 (20180101) Y02A 50/58 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526488 | Ferrari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | APG Polytech, LLC (Wilmington, Delaware) |
| ASSIGNEE(S) | APG Polytech, LLC (Wilmington, Delaware) |
| INVENTOR(S) | Gianluca Ferrari (Portograuaro, Italy); D. Jeffrey Black (Akron, Ohio) |
| ABSTRACT | Disclosed herein is a preform having a preform wall. The preform wall preferably comprises a composition comprising at least one polyester component, a transition metal catalyst, and a vegetable oil. The vegetable oil may comprise at least one molecule having a double allylic structure. The at least one polyester component may comprise at least one acid unit and at least one diol unit. The concentration of double allylic structures of the vegetable oil in the composition may be greater than 5.0 meq/kg of all of the polyester components. The preform has improved aesthetic characteristics. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/735739 |
| ART UNIT | 1768 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 49/0005 (20130101) B29C 49/06 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/003 (20130101) B29K 2105/0014 (20130101) B29K 2995/0053 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7158 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 5/20 (20130101) C08K 5/098 (20130101) C08K 5/3445 (20130101) C08K 11/00 (20130101) C08K 2003/2241 (20130101) C08K 2201/012 (20130101) Compositions of Macromolecular Compounds C08L 67/02 (20130101) C08L 67/02 (20130101) C08L 67/03 (20130101) C08L 91/00 (20130101) Original (OR) Class C08L 91/00 (20130101) C08L 2201/08 (20130101) C08L 2203/10 (20130101) C08L 2203/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526526 | Guenthner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson, AFB, Ohio); Nano Hydrophobics, Inc. (San Francisco, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright Patterson AFB, Ohio) |
| INVENTOR(S) | Andrew Guenthner (Lancaster, California); Jeffrey Alston (Palmdale, California); Peter H. Boyd (San Francisco, California); Joseph M. Mabry (Lancaster, California); Timothy W. Rost (Fremont, California) |
| ABSTRACT | In some aspects, the present invention relates generally to self-release compositions and methods useful for the removal or prevention of mineral scaling and, more particularly, to surface coatings and surface treatments that resist, prevent, or aid in removal of mineral scaling. In some aspects, the self-release coating includes a polyhedral oligomeric silsesquioxane and a thermoplastic or an additive. |
| FILED | Monday, April 08, 2019 |
| APPL NO | 16/377392 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/36 (20130101) B05D 1/38 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/24 (20130101) C08G 77/045 (20130101) Compositions of Macromolecular Compounds C08L 25/06 (20130101) C08L 33/08 (20130101) C08L 33/12 (20130101) C08L 33/12 (20130101) C08L 33/20 (20130101) C08L 81/06 (20130101) C08L 83/00 (20130101) C08L 83/00 (20130101) C08L 83/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/00 (20130101) C09D 7/20 (20180101) C09D 133/12 (20130101) C09D 133/12 (20130101) C09D 183/08 (20130101) C09D 183/08 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/52 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526624 | Angenent et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Largus T. Angenent (Tübingen, Germany); Leo Kucek (Waukesha, Wisconsin) |
| ABSTRACT | Methods and systems to produce product compositions comprising caprylate products using chain-elongating bacteria. For example, the caprylate product in the product composition is n-caprylic acid (C8) and the n-caprylic (C8) to n-caproic (C6) acid ratio is higher than 1:1. These methods use chain elongation towards C8 rather than C6. High n-caprylate productivity and specificity was accomplished by: 1) feeding a substrate with, for example, ethanol as the carbon source or alternatively, a high ethanol-to-acetate ratio as the carbon source; 2) extracting caprylate product(s) (e.g., n-caprylate product) from the bioreactor broth; and 3) acclimating an efficient chain-elongating microbiome. The methods can produce caprylate products such as, for example, n-caprylic acid, which is a higher value chemical than C4 and C6. |
| FILED | Friday, May 26, 2017 |
| APPL NO | 15/607188 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
10526628 — Enzyme-mediated assimilation of DNA-functionalized single-walled carbon nanotubes (SWNTs)
| US 10526628 | Arnett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Clint M. Arnett (Mahomet, Illinois); Charles P. Marsh (Urbana, Illinois); Jae Hee Han (Gyeonggi-do, South Korea); Michael S. Strano (Lexington, Massachusetts); Charles R. Welch (Vicksburg, Mississippi); Thomas A. Carlson (Champaign, Illinois) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Clint M. Arnett (Mahomet, Illinois); Charles P. Marsh (Urbana, Illinois); Jae Hee Han (Gyeonggi-do, South Korea); Michael S. Strano (Lexington, Massachusetts); Charles R. Welch (Vicksburg, Mississippi); Thomas A. Carlson (Champaign, Illinois) |
| ABSTRACT | Select embodiments of the present invention employ biological means to direct assemble CNT-based nanostructures, allowing for scaling to macrostructures for manufacture. In select embodiments of the present invention, a method is provided for assembling DNA-functionalized SWNTs by phosphodiester bonding catalyzed by ssDNA-ligase to form macroscopic CNT aggregates. |
| FILED | Thursday, October 06, 2011 |
| APPL NO | 13/267002 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/174 (20170801) C01B 2202/02 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526897 | Swift et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Anthony B. Swift (North Waterboro, Maine); Paul M. Lutjen (Kennebunkport, Maine) |
| ABSTRACT | A gas turbine engine component includes a wall portion that includes a first side and a second opposite side. A plurality of passages extends between the first side of the wall portion and the second side of the wall portion and includes a plurality of inlets located on the first side of the wall portion. A plurality of outlets are located on a second side of the wall portion. The plurality of outlets include a first plurality of outlets located on a first side of the plurality of inlets and a second plurality of outlets located on a second side of the plurality of inlets. |
| FILED | Wednesday, September 30, 2015 |
| APPL NO | 14/870175 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) Original (OR) Class F01D 9/02 (20130101) F01D 11/08 (20130101) F01D 25/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/202 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526905 | Estes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Matthew B. Estes (South Windsor, Connecticut); Bryan P. Dube (Columbia, Connecticut) |
| ABSTRACT | An asymmetric vane assembly includes a high count vane section including a first plurality of vanes oriented in a first position. The asymmetric vane assembly also includes a low count vane section including a second plurality of vanes oriented in a second position, a total number of vanes in the first plurality of vanes being greater than a total number of vanes in the second plurality of vanes, and each vane of the high count vane section and each vane of the low count vane section having substantially similar internal core geometry. |
| FILED | Wednesday, March 29, 2017 |
| APPL NO | 15/473222 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/73 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526911 | Pratt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | William S. Pratt (West Hartford, Connecticut); David Maliniak (Guilford, Connecticut); Christopher St. Mary (Hebron, Connecticut) |
| ABSTRACT | A synchronization ring for a variable vane assembly of a gas turbine engine may include a first ring portion and a second ring portion. The first ring portion and the second ring portion may be detachably coupled together to jointly define a plurality of cylindrical bores circumferentially distributed around the synchronization ring and extending radially through the synchronization ring. |
| FILED | Thursday, June 22, 2017 |
| APPL NO | 15/630650 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 17/162 (20130101) Original (OR) Class F01D 25/246 (20130101) Non-positive-displacement Pumps F04D 29/563 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/60 (20130101) F05D 2260/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526916 | Schwarz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Frederick M. Schwarz (Glastonbury, Connecticut); Paul W. Duesler (Manchester, Connecticut) |
| ABSTRACT | A heat exchanger for use in a gas turbine engine has a central body including an inlet manifold and at least one tube providing an outlet manifold, and a plurality of tubes communicating holes in an outer periphery of the inlet manifold to holes in an outer periphery of the outlet manifold, and passages for cooling air to pass across the tubes. A gas turbine engine is also disclosed. |
| FILED | Tuesday, April 26, 2016 |
| APPL NO | 15/138727 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 17/105 (20130101) F01D 25/12 (20130101) Original (OR) Class F01D 25/24 (20130101) Non-positive-displacement Pumps F04D 29/321 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/213 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/0475 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 9/001 (20130101) F28F 9/0075 (20130101) F28F 9/0131 (20130101) F28F 9/0273 (20130101) F28F 21/087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526917 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Corey D. Anderson (East Hartford, Connecticut); Brandon W. Spangler (Vernon, Connecticut) |
| ABSTRACT | An exemplary gas turbine engine includes a turbine section positioned about an engine central longitudinal axis. The turbine section includes a component with a platform providing a lip, a rail extending radially from the platform and at an axial location spaced from an outer axial extension of the lip. An inner face of the rail and a surface of the platform at least partially provide a cavity. At least one opening extends from the inner face to an outer face of the rail opposite the inner face to provide fluid communication from the cavity to the lip. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/884473 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 25/12 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/12 (20130101) F05D 2240/80 (20130101) F05D 2260/201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526975 | Howell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Eric A. Howell (Ballwin, Missouri); Jeffrey M. Roach (Saint Charles, Missouri); Thomas W. Omohundro (Saint Charles, Missouri) |
| ABSTRACT | A power extraction system and method for a gas turbine engine of a vehicle are provided. The system has an HP spool tower shaft coupled between an HP spool of the gas turbine engine and an accessory gearbox assembly coupled to the gas turbine engine. The HP spool tower shaft extracts mechanical power from the HP spool. The system has an LP spool tower shaft coupled between an LP spool of the gas turbine engine and the accessory gearbox assembly. The LP spool tower shaft extracts mechanical power from the LP spool. The system further has the accessory gearbox assembly having an accessory drive combining the mechanical power from both the HP spool and LP spool, having a planetary gear train coupled to the accessory drive, and having one or more engine-driven accessories coupled to the planetary gear train and driven by a planetary gear train output to generate power. |
| FILED | Wednesday, November 30, 2016 |
| APPL NO | 15/365932 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/12 (20130101) B64D 33/00 (20130101) B64D 2013/0618 (20130101) B64D 2221/00 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/32 (20130101) Original (OR) Class F02C 7/36 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2260/40311 (20130101) Gearing F16H 37/065 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/671 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527025 | Jindal |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNTIED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Ravi Chand Jindal (West Palm Beach, Florida) |
| ABSTRACT | A multi-spring mechanical actuator includes a first spring having a first spring constant and a second spring having a second spring constant different than the first spring constant, wherein a load actuator is configured against the first spring under one loading condition and against a spring differential between the first spring and the second spring under a different loading condition. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/863420 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 1/02 (20130101) F03G 1/10 (20130101) Original (OR) Class Springs; Shock-absorbers; Means for Damping Vibration F16F 1/128 (20130101) F16F 3/04 (20130101) F16F 2228/066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527192 | Cauley, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Talis Biomedical Corporation (Menlo Park, California) |
| ASSIGNEE(S) | Talis Biomedical Corporation (Menlo Park, California) |
| INVENTOR(S) | Thomas H. Cauley, III (Redwood City, California); John Dixon (Moss Beach, California) |
| ABSTRACT | Rotary valves and methods of using, manufacturing, and storing the same are provided herein. The rotary valve includes a rotor and a stator, biased toward one another to form a fluid tight seal. In some implementations, the rotor comprises an integrated flow channel containing a porous solid support. Frequently, the interface between rotor and stator is made fluid-tight using a gasket. Some implementations of the rotary valve include a displaceable spacer to prevent the gasket from sealing against at least one of the rotor and stator prior to operation, wherein when the spacer is displaced, the gasket seals the rotor and stator together in a fluid-tight manner. |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/898064 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/565 (20130101) B01L 3/567 (20130101) B01L 2300/042 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 99/0013 (20130101) Original (OR) Class F16K 99/0028 (20130101) F16K 2099/0084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527358 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kelvin Thermal Technologies, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | KELVIN THERMAL TECHNOLOGIES, INC. (Boulder, Colorado) |
| INVENTOR(S) | Ronggui Yang (Broomfield, New York); Yung-Cheng Lee (Boulder, Colorado); Victor M. Bright (Boulder, Colorado); Chen Li (Columbia, South Carolina); Christopher Oshman (Boulder, Colorado); Bo Shi (Nanjing, China PRC); Jen-Hau Cheng (Boulder, Colorado); George P. Peterson (Atlanta, Georgia) |
| ABSTRACT | Methods, apparatuses, and systems are disclosed for flexible thermal ground planes. A flexible thermal ground plane may include a support member. The flexible thermal ground plane may include an evaporator region or multiple evaporator regions configured to couple with the support member. The flexible thermal ground plane may include a condenser region or multiple condenser regions configured to couple with the support member. The evaporator and condenser region may include a microwicking structure. The evaporator and condenser region may include a nanowicking structure coupled with the micro-wicking structure, where the nanowicking structure includes nanorods. The evaporator and condenser region may include a nanomesh coupled with the nanorods and/or the microwicking structure. Some embodiments may include a micromesh coupled with the nanorods and/or the microwicking structure. |
| FILED | Thursday, October 13, 2016 |
| APPL NO | 15/292932 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/26 (20130101) B23P 2700/09 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/04 (20130101) F28D 15/046 (20130101) F28D 15/0233 (20130101) F28D 15/0241 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/427 (20130101) H01L 23/473 (20130101) H01L 23/3677 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49353 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527391 | Moser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Alex E. Moser (Washington, District of Columbia); David L. Knies (Marbury, Maryland); Kenneth S. Grabowski (Alexandria, Virginia) |
| ABSTRACT | An armor system includes an armor plate, and an appliqué affixed to an exterior of the armor plate, wherein the appliqué has a density increasing in a direction towards the armor plate and configured to minimize reflection of a blast wave from the armor plate. The coupling system comprises a binder material that surrounds filler particles configured to create an impedance gradient parallel to the impulse propagation direction. |
| FILED | Friday, February 09, 2018 |
| APPL NO | 15/892785 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527393 | Sapp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Nicole Sapp (Augusta, New Jersey); Jeffrey Darbig (Flanders, New Jersey); Jonathan Escobar (Stony Point, New York) |
| ABSTRACT | A medium caliber high kinetic energy round with tracer and self-destruct mechanism having an optimized kinetic energy projectile incorporating a fully hardened projectile body and an explosive self-destruct mechanism for a medium caliber high rate of fire round. The medium caliber high kinetic energy ammunition round incorporates a multiple piece sub-projectile that integrates a tracer and high explosive self-destruct mechanism to neutralize the penetrator during self-destruct and minimize collateral damage during firing. |
| FILED | Monday, October 22, 2018 |
| APPL NO | 16/166266 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 8/14 (20130101) F42B 12/06 (20130101) Original (OR) Class F42B 12/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527419 | Challoner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Anthony Dorian Challoner (Manhattan Beach, California); Parsa Taheri-Tehrani (Davis, California); David Horsley (Berkeley, California) |
| ASSIGNEE(S) | Inertialwave (Manhattan Beach, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Anthony Dorian Challoner (Manhattan Beach, California); Parsa Taheri-Tehrani (Davis, California); David Horsley (Berkeley, California) |
| ABSTRACT | A compact Inertial Wave Angle Gyroscope (IWAG) is operated using a phase lock loop to track resonator phase and a baseband regulator to null quadrature. The resonator velocity or its components computed from precession angle are first determined at baseband and then applied to gain matrices in order to generate the feedback control forces for self-precession, cancellation of damping and compensation of anisodamping. The inertial rotation input is determined from the measured total precession angle by removing the computed or calibrated self-precession angle. The resonator energy can be regulated to a fixed magnitude and the baseband feedback force for self-precession at a fixed rate determined from components computed from precession angle such that the total force is in phase with baseband velocity but has fixed magnitude. The IWAG inertial rotation input can be determined from the measured total precession rate by removing the computed self-precession rate. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/436726 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5684 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527625 | Shih et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wei-Heng Shih (Bryn Mawr, Pennsylvania); Wan Y. Shih (Bryn Mawr, Pennsylvania); Giang Au (Sicklerville, New Jersey); Ari D. Brooks (Cherry Hill, New Jersey); Vanlila K. Swami (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wei-Heng Shih (Bryn Mawr, Pennsylvania); Wan Y. Shih (Bryn Mawr, Pennsylvania); Giang Au (Sicklerville, New Jersey); Ari D. Brooks (Cherry Hill, New Jersey); Vanlila K. Swami (Philadelphia, Pennsylvania) |
| ABSTRACT | One or more aqueous, near infrared emitting, high yield, highly photoluminescent, stable quantum dots conjugated to one or more biomarkers specific moieties. The conjugated quantum dots have an enhanced detection sensitivity and selectivity and may be formed using a novel and efficient method for conjugating one or more biomarker specific moieties to the quantum dots. The invention is further directed to a method for using the conjugated quantum dots for cancer detection in the margin of excised tissue. |
| FILED | Wednesday, July 06, 2016 |
| APPL NO | 15/202710 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) B82Y 40/00 (20130101) Peptides C07K 16/22 (20130101) C07K 16/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/532 (20130101) G01N 33/533 (20130101) G01N 33/551 (20130101) G01N 33/574 (20130101) G01N 33/588 (20130101) G01N 33/57484 (20130101) G01N 33/57488 (20130101) Original (OR) Class G01N 33/57492 (20130101) G01N 2333/475 (20130101) G01N 2333/705 (20130101) G01N 2400/00 (20130101) G01N 2458/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/774 (20130101) Y10S 977/824 (20130101) Y10S 977/892 (20130101) Y10S 977/927 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527686 | Mount et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Emily Mount (Panama City, Florida); Neil Claussen (Panama City, Florida) |
| ABSTRACT | A method and system are provided for performing magnetic anomaly sensing. Each of two magnetometers generates magnetic field measurements. The magnetometers define a one-dimensional gradiometer having a baseline between them. A difference value is generated using the magnetic field measurements. The magnetometers are independently moved to maintain the baseline when the difference value is unchanging. Detection of a magnetic anomaly by a first magnetometer is indicated when the difference value deviates. The second magnetometer is then maneuvered until the magnetic field measurements generated thereby are indicative of detection of the magnetic anomaly by the second magnetometer. When this occurs, an adjusted baseline is defined between the magnetometers. At least one of the magnetometers is maneuvered to position the adjusted baseline in each of three orthogonal dimensions. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804300 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/022 (20130101) Original (OR) Class G01R 33/0206 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527689 | Rosen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Matthew S. Rosen (Somerville, Massachusetts); Mathieu Sarracanie (Somerville, Massachusetts); Najat Salameh (Somerville, Massachusetts) |
| ABSTRACT | A system and method for system for performing a magnetic resonance imaging (MRI) process using an MRI system is provided. A coil system includes a substrate configured to follow a contour of a portion of a subject to be imaged by the MRI system and at least one coil coupled to the substrate and forming a spiral pattern. |
| FILED | Friday, March 13, 2015 |
| APPL NO | 15/125860 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/08 (20130101) A61B 5/055 (20130101) A61B 5/0402 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/084 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/445 (20130101) G01R 33/5601 (20130101) G01R 33/5614 (20130101) G01R 33/5635 (20130101) G01R 33/34046 (20130101) Original (OR) Class G01R 33/34084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527720 | Apker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Thomas Apker (Alexandria, Virginia); Christopher T. Rodenbeck (Annandale, Virginia); Thomas Pizzillo (Dunkirk, Maryland) |
| ABSTRACT | Systems and method are provided for using millimeter-wave radar for terrain-aided navigation in support of autonomous guidance, landing, and mapping functions in all weather for unmanned air vehicles (UAVs). In an embodiment, a UAV can generate a map, based on millimeter-wave (MMW) radar returns, that rejects a large number of radar measurements as clutter and generates a flight path using waypoints based on the map. Embodiments of the present disclosure provide a means of correlating MMW radar returns with high resolution terrain maps to enable navigation in GPS-denied environments. This process significantly reduces cost, development time, and complexity when compared to conventional approaches. |
| FILED | Monday, December 18, 2017 |
| APPL NO | 15/845067 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/141 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/005 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/04 (20130101) G01S 13/86 (20130101) G01S 13/89 (20130101) Original (OR) Class G01S 13/94 (20130101) G01S 13/9064 (20190501) G01S 13/9303 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/12 (20130101) G05D 1/0088 (20130101) G05D 1/101 (20130101) G05D 1/104 (20130101) Traffic Control Systems G08G 5/0008 (20130101) G08G 5/0021 (20130101) G08G 5/025 (20130101) G08G 5/045 (20130101) G08G 5/0052 (20130101) G08G 5/0069 (20130101) G08G 5/0078 (20130101) G08G 5/0086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527729 | Crouch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Blackmore Sensors and Analytics, LLC (Palo Alto, California); Montana State University (Bozeman, Montana) |
| ASSIGNEE(S) | BLACKMORE SENSORS AND ANALYTICS, LLC (Palo Alto, California); MONTANA STATE UNIVERSITY (Bozeman, Montana) |
| INVENTOR(S) | Stephen C. Crouch (Bozeman, Montana); Brant M. Kaylor (Merrimack, New Hampshire); Zeb W. Barber (Bozeman, Montana); Randy R. Reibel (Bozeman, Montana) |
| ABSTRACT | Laser 3D imaging techniques include splitting a laser temporally-modulated waveform of bandwidth B and duration D from a laser source into a reference beam and a target beam and directing the target beam onto a target. First data is collected, which indicates amplitude and phase of light relative to the reference beam received at each of a plurality of different times during a duration D at each optical detector of an array of one or more optical detectors perpendicular to the target beam. Steps are repeated for multiple sampling conditions, and the first data for the multiple sampling conditions are synthesized to form one or more synthesized sets. A 3D Fourier transform of each synthesized set forms a digital model of the target for each synthesized set with a down-range resolution based on the bandwidth B. |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/026085 |
| ART UNIT | 2422 — Cable and Television |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/325 (20130101) G01S 17/895 (20130101) Original (OR) Class Holographic Processes or Apparatus G03H 1/0005 (20130101) G03H 1/0443 (20130101) G03H 1/0465 (20130101) G03H 1/0866 (20130101) G03H 2001/046 (20130101) G03H 2001/0445 (20130101) G03H 2001/2655 (20130101) G03H 2222/33 (20130101) G03H 2226/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527783 | Badding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | John V. Badding (State College, Pennsylvania); Justin R. Sparks (Coopersburg, Pennsylvania) |
| ABSTRACT | The invention relates to Cr2+:ZnSe core optical fibers and methods of fabricating thereof, including a hybrid physical-chemical vapor deposition reaction. The invention relates also to Cr2+:ZnSe optical fiber lasers, in particular to a crystalline semiconductor optical fiber laser. |
| FILED | Thursday, August 17, 2017 |
| APPL NO | 15/679351 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/32 (20130101) C03C 3/321 (20130101) C03C 13/043 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02395 (20130101) Original (OR) Class G02B 13/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527784 | Koste et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Niskayuna, New York) |
| INVENTOR(S) | Glen Peter Koste (Schenectady, New York); Hendrik Pieter Jacobus de Bock (Clifton Park, New York); Cheng-Po Chen (Niskayuna, New York) |
| ABSTRACT | Aspects of the present disclosure are directed toward designs and methods improving optical sensing, wavelength division multiplexed (WDM) telecommunication transceivers, WDM add/drops, and spectrometer techniques that may benefit from a stable wavelength reference. The disclosed designs and methods are useful in the manufacture of a stable wavelength reference that may compensate for temperature variations. |
| FILED | Thursday, November 15, 2018 |
| APPL NO | 16/192472 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/165 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 2001/446 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 1/14 (20130101) G01K 11/3206 (20130101) Optical Elements, Systems, or Apparatus G02B 6/12 (20130101) Original (OR) Class G02B 6/124 (20130101) G02B 6/02176 (20130101) G02B 6/4266 (20130101) G02B 6/29338 (20130101) G02B 6/29352 (20130101) G02B 2006/12061 (20130101) G02B 2006/12107 (20130101) G02B 2006/12121 (20130101) G02B 2006/12123 (20130101) G02B 2006/12135 (20130101) G02B 2006/12138 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527920 | Wo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DHPC Technologies, Inc. (Woodbridge, New Jersey) |
| ASSIGNEE(S) | DHPC Technologies, Inc. (Woodbridge, New Jersey) |
| INVENTOR(S) | Yei Wo (East Brunswick, New Jersey); Bruce P. Boczar (Trevose, Pennsylvania); Richard Gifford (Toms River, New Jersey); Joseph M. Aletta (Jackson, New Jersey) |
| ABSTRACT | A system, method, and device for simulating an emission signature, which contains representative intensity, temporal, and spectral emission profiles of a weapon system or weapon platform for the purpose of testing an optical detection device. A projection system optically projects the emission signature. A projection screen is provided that has a concave curvature. The concave curvature possesses a first focal point and a second focal point. Any light emanating from the second focal toward the projection screen is reflected by the projection screen toward the first focal point. The projection system is positioned at the second focal point and the optical detection system is positioned at the first focal point. In this manner, the emission signature projected by the projector system is redirected to the optical detection system. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/297538 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/2221 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 21/56 (20130101) G03B 21/58 (20130101) G03B 21/60 (20130101) Original (OR) Class G03B 21/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528051 | Perkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Alexander Douglas Perkins (Arlington, Massachusetts); Kevin Blankespoor (Arlington, Massachusetts) |
| ABSTRACT | An example implementation includes (i) receiving sensor data that indicates topographical features of an environment in which a robotic device is operating, (ii) processing the sensor data into a topographical map that includes a two-dimensional matrix of discrete cells, the discrete cells indicating sample heights of respective portions of the environment, (iii) determining, for a first foot of the robotic device, a first step path extending from a first lift-off location to a first touch-down location, (iv) identifying, within the topographical map, a first scan patch of cells that encompass the first step path, (v) determining a first high point among the first scan patch of cells; and (vi) during the first step, directing the robotic device to lift the first foot to a first swing height that is higher than the determined first high point. |
| FILED | Thursday, January 26, 2017 |
| APPL NO | 15/416361 |
| ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1664 (20130101) Motor Vehicles; Trailers B62D 57/032 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0212 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528063 | Cherepinsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporaton (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Igor Cherepinsky (Sandy Hook, Connecticut); Prateek Sahay (Acton, Massachusetts); Mark D. Ward (Milford, Connecticut); Sacha Duff (Shelton, Connecticut); Margaret M. Lampazzi (Oxford, Connecticut) |
| ABSTRACT | An example computer-implemented method for natural language mission planning includes: responsive to receiving a request to initiate mission planning for a selected mission type from a plurality of mission types, constructing, by a processing system, a mission narrative that describes a mission intent based on the selected mission type, the mission narrative comprising a plurality of fields; populating, by the processing system, the plurality of fields in the mission narrative from an autonomous mission manager based on the selected mission type with options to be selected by a mission planner; responsive to presenting the populated plurality of fields to the mission planner, filling, by the processing system, the mission narrative with the received selected options; creating, by the processing system, an optimized mission plan based on the mission narrative; and controlling, by the processing system, a vehicle based on the optimized mission plan. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/863238 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 13/503 (20130101) B64C 27/06 (20130101) B64C 27/82 (20130101) B64C 39/02 (20130101) B64C 2027/8236 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/101 (20130101) Original (OR) Class Electric Digital Data Processing G06F 3/0482 (20130101) G06F 17/243 (20130101) G06F 17/248 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528097 | Cher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Chen-Yong Cher (Port Chester, New York); Haifeng Qian (Mount Kisco, New York) |
| ABSTRACT | An integrated circuit (IC) includes: a plurality of hardware performance counters; a thermal sensor; and a micro-controller. The micro-controller generates a plurality of thermal predictors based on values of the counters and temperatures sensed by the thermal sensor. The thermal predictors include first and second rising thermal delta predictors to predict rising temperature deltas and first and second falling thermal delta predictors to predict falling temperature deltas. The micro-controller predicts a future temperature of the IC based on an idle temperature of the IC and a selected one of the temperature deltas. |
| FILED | Thursday, March 10, 2016 |
| APPL NO | 15/066761 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/42 (20130101) Electric Digital Data Processing G06F 1/206 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528595 | Bilinski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mark Bilinski (Vista, California); Ryan Gabrys (San Diego, California) |
| ABSTRACT | A method for synchronizing datasets comprising the steps of: (1) partitioning each dataset into a plurality of bins according to a first partitioning rule, wherein each bin contains a random subset of elements of symmetric difference taken from a universe of all possible elements, (2) performing a first round of polynomial interpolation (PI) at a first encoding threshold on each bin of the first-partitioned datasets, wherein if any bin contains a number of elements that is less than or equal to the first encoding threshold the elements contained therein are decoded during the first PI round, and wherein if any bin contains a number of elements that is greater than the first encoding threshold the elements contained therein are not decoded during the first PI round; and (3) synchronizing the datasets based on the decoded elements. |
| FILED | Thursday, April 13, 2017 |
| APPL NO | 15/486746 |
| ART UNIT | 2158 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/27 (20190101) G06F 16/273 (20190101) G06F 16/275 (20190101) G06F 16/278 (20190101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 67/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528687 | Johnson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Regents of the University of Minnesota (Minneapolis, Minnesota); ETH Zürich (Zürich, Switzerland) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); ETH Zürich (Zürich, Switzerland) |
| INVENTOR(S) | Brian Benjamin Johnson (Denver, Colorado); Nathan Ainsworth (Brown Deer, Wisconsin); Sairaj Vijaykumar Dhople (Minneapolis, Minnesota); Mohit Sinha (St. Paul, Minnesota); Florian Anton Dörfler (Zürich, Switzerland) |
| ABSTRACT | Virtual oscillator control systems, devices, and techniques are provided. One example device includes a processor configured to implement a virtual oscillator circuit and output an oscillating waveform based on the virtual oscillator circuit and power electronics operatively coupled to the processor and configured to convert, based on the oscillating waveform, direct current (DC) electricity to alternating current (AC) electricity. The processor may be further configured to extract, from the virtual oscillator circuit, a virtual current based on an output current of the AC electricity, and output the oscillating waveform further based on an input voltage of the DC electricity. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 15/581824 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/2513 (20130101) G01R 21/133 (20130101) G01R 31/42 (20130101) G01R 35/04 (20130101) Electric Digital Data Processing G06F 1/28 (20130101) G06F 1/30 (20130101) G06F 17/40 (20130101) G06F 17/5036 (20130101) Original (OR) Class G06F 17/5045 (20130101) G06F 17/5063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528729 | Friedman et al. |
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| FUNDED BY |
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| APPLICANT(S) | SMART INFORMATION FLOW TECHNOLOGIES LLC (Minneapolis, Minnesota) |
| ASSIGNEE(S) | SMART INFORMATION FLOW TECHNOLOGIES LLC (Minneapolis, Minnesota) |
| INVENTOR(S) | Scott Ehrlich Friedman (Minneapolis, Minnesota); David John Musliner (Plymouth, Minnesota); Peter Kelly Keller (Saint Paul, Minnesota) |
| ABSTRACT | Methods, systems, and computer-readable storage medium including a computer program product for defending against cyber-attacks are provided. One method includes receiving, by a processor, program code and automatically generating a chronomorphic binary for the program code. The method further includes storing the chronomorphic binary in an executable memory space and diversifying the executable memory space for the chronomorphic binary during runtime of the program code. A system includes memory configured for storing a defense module and a processor connected to the memory. The processor, when executing the defense module, is configured for performing the above-referenced method. One computer program product includes computer code for performing the above-referenced method. |
| FILED | Monday, October 22, 2018 |
| APPL NO | 16/167161 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 8/52 (20130101) G06F 21/56 (20130101) Original (OR) Class G06F 21/563 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528734 | Keppler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | David Keppler (Herndon, Virginia); Ivan Lozano (Arlington, Virginia); Joseph Portner (Hampton, Virginia); Andrew Pyles (Williamsburg, Virginia); Christina L. Johns (Arlington, Virginia); David Bryson (Montgomery, Alabama) |
| ABSTRACT | A system and method for implementing a software emulation environment is provided. In one example, a mobile application can interface with an emulation environment that can be used to test whether the mobile application includes malware that can compromise the security and integrity of an enterprise's computing infrastructure. When the mobile application issues a call for data, a device mimic module can intercept the call and determine if the call includes a call for one or more checkable artifacts that can reveal the existence of the emulation environment. If such a call for data occurs, the device mimic module can provide one or more spoofed checkable artifacts that have been recorded from a real-world mobile device. In this way, the existence of the emulation environment can be concealed so as to allow for a more thorough analysis of a mobile application for potential hidden malware. |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/081280 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/552 (20130101) G06F 21/554 (20130101) G06F 21/566 (20130101) Original (OR) Class G06F 21/577 (20130101) G06F 2221/033 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101) H04L 63/1491 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528843 | Andreopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alexander Andreopoulos (San Jose, California); Steven K. Esser (San Jose, California); Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | Embodiments of the invention provide a method of visual saliency estimation comprising receiving an input video of image frames. Each image frame has one or more channels, and each channel has one or more pixels. The method further comprises, for each channel of each image frame, generating corresponding neural spiking data based on a pixel intensity of each pixel of the channel, generating a corresponding multi-scale data structure based on the corresponding neural spiking data, and extracting a corresponding map of features from the corresponding multi-scale data structure. The multi-scale data structure comprises one or more data layers, wherein each data layer represents a spike representation of pixel intensities of a channel at a corresponding scale. The method further comprises encoding each map of features extracted as neural spikes. |
| FILED | Wednesday, December 27, 2017 |
| APPL NO | 15/855820 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/00744 (20130101) G06K 9/4604 (20130101) G06K 9/4652 (20130101) G06K 9/4671 (20130101) Original (OR) Class G06K 9/4676 (20130101) Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528848 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Jeffrey John Nirschl (Philadelphia, Pennsylvania); Andrew Janowczyk (East Meadow, New York); Eliot G. Peyster (Philadelphia, Pennsylvania); Michael D. Feldman (Wilmington, Delaware); Kenneth B. Margulies (Villanova, Pennsylvania) |
| ABSTRACT | Methods, apparatus, and other embodiments predict heart failure from WSIs of cardiac histopathology using a deep learning convolutional neural network (CNN). One example apparatus includes a pre-processing circuit configured to generate a pre-processed WSI by downsampling a digital WSI; an image acquisition circuit configured to randomly select a set of non-overlapping ROIs from the pre-processed WSI, and configured to provide the set of non-overlapping ROIs to a deep learning circuit; a deep learning circuit configured to generate an image-level probability that a member of the set of non-overlapping ROIs is a failure/abnormal pathology ROI using a CNN; and a classification circuit configured to generate a patient-level probability that the patient from which the region of tissue represented in the WSI was acquired is experiencing failure or non-failure based, at least in part, on the image-level probability. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 15/799129 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/2054 (20130101) G06K 9/6256 (20130101) Original (OR) Class G06K 9/6277 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0472 (20130101) Image Data Processing or Generation, in General G06T 3/40 (20130101) G06T 2207/10024 (20130101) G06T 2207/20076 (20130101) G06T 2207/30048 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529127 | Black et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Michael J. Black (Tuebingen, Germany); Peng Guan (Mountain View, California) |
| ABSTRACT | A system generates a clothing deformation model which models one or more of a pose-dependent clothing shape variation which is induced by underlying body pose parameters, a pose-independent clothing shape variation which is induced by clothing size and underlying body shape parameters and a clothing shape variation including a combination of the pose-dependent clothing shape variation and/or the pose-independent clothing shape variation. The system generates, for an input human body, a custom-shaped garment associated with a clothing type by mapping, via the clothing deformation model, body shape parameters of the input human body to clothing shape parameters of the clothing type and dresses the input human body with the custom-shaped garment. |
| FILED | Wednesday, July 03, 2019 |
| APPL NO | 16/502718 |
| ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 17/5009 (20130101) G06F 2217/32 (20130101) Image Data Processing or Generation, in General G06T 17/00 (20130101) Original (OR) Class G06T 19/20 (20130101) G06T 2210/16 (20130101) G06T 2219/2016 (20130101) G06T 2219/2021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529416 | Soykal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Oney Soykal (Alexandria, Virginia); Thomas L. Reinecke (Alexandria, Virginia); Samuel G. Carter (Waldorf, Maryland) |
| ABSTRACT | Devices and methods for the detection of magnetic fields, strain, and temperature using the spin states of a V |
| FILED | Friday, September 22, 2017 |
| APPL NO | 15/712403 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0032 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 7/22 (20130101) G11C 11/16 (20130101) G11C 11/44 (20130101) Original (OR) Class G11C 11/161 (20130101) G11C 13/04 (20130101) G11C 13/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529450 | Corey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Medtronic, Inc. (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Medtronic, Inc. (Minneapolis, Minnesota) |
| INVENTOR(S) | Robert A. Corey (Arden Hills, Minnesota); Gregory J. Loxtercamp (Edina, Minnesota); Heather Diane Orser (Farmington, Minnesota); Scott R. Stanslaski (Shoreview, Minnesota); Jadin C. Jackson (Roseville, Minnesota) |
| ABSTRACT | Techniques are described for real-time phase detection. For the phase detection, a signal is correlated with a frequency component of a frequency band whose phase is being detected, and the correlation includes predominantly decreasing weighting of past portions of the signals. |
| FILED | Tuesday, August 07, 2018 |
| APPL NO | 16/057417 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/048 (20130101) A61B 5/686 (20130101) A61B 5/04014 (20130101) A61B 5/4088 (20130101) A61B 5/4094 (20130101) A61B 5/4836 (20130101) A61B 5/4839 (20130101) A61B 5/7246 (20130101) A61B 5/7257 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529648 | Brunschwiler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Thomas J. Brunschwiler (Thalwil, Switzerland); Timothy J. Chainer (Putnam Valley, New York); Evan G. Colgan (Montvale, New Jersey); Arvind Raj Mahankali Sridhar (Zurich, Switzerland); Chin Lee Ong (Horgen, Switzerland); Pritish R. Parida (Stamford, Connecticut); Gerd Schlottig (Uitikon, Switzerland); Mark D. Schultz (Ossining, New York); Joel A. Silberman (Somers, New York) |
| ABSTRACT | A structure for cooling an integrated circuit. The structure may include; an interposer cold plate having at least two expanding channels, each expanding channel having a flow direction from a channel inlet to a channel outlet, the flow direction having different directions for at least two of the at least two expanding channels, the channel inlet having an inlet width and the channel outlet having an outlet width, wherein the inlet width is less than the outlet width. |
| FILED | Tuesday, February 13, 2018 |
| APPL NO | 15/894974 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4871 (20130101) H01L 23/427 (20130101) Original (OR) Class H01L 23/473 (20130101) H01L 24/16 (20130101) H01L 24/17 (20130101) H01L 24/73 (20130101) H01L 25/0657 (20130101) H01L 2224/16145 (20130101) H01L 2224/16227 (20130101) H01L 2224/17181 (20130101) H01L 2224/32225 (20130101) H01L 2224/32245 (20130101) H01L 2224/73253 (20130101) H01L 2225/06513 (20130101) H01L 2225/06517 (20130101) H01L 2225/06565 (20130101) H01L 2225/06589 (20130101) H01L 2924/15311 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529674 | Grayson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Matthew Grayson (Evanston, Illinois); Yang Tang (Evanston, Illinois) |
| ABSTRACT | Systems and methods provide a device for characterizing a thin film, including a conducting or insulating substrate, an active layer on the conducting or insulating substrate to be characterized, and a plurality of stripline electrodes on the active layer. The plurality of stripline electrodes include a pitch width of a same order as the thickness of the active layer and strip width smaller than the thickness of the active layer. |
| FILED | Tuesday, November 28, 2017 |
| APPL NO | 15/823933 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 1/06755 (20130101) G01R 1/06777 (20130101) G01R 15/20 (20130101) G01R 27/14 (20130101) G01R 31/2831 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 22/14 (20130101) H01L 22/34 (20130101) H01L 23/52 (20130101) H01L 23/585 (20130101) Original (OR) Class H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/323 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529775 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Yang Lv (New Brighton, Minnesota); Mahdi Jamali (Folsom, California) |
| ABSTRACT | This disclosure describes an example device that includes a first contact line, a second contact line, a spin-orbital coupling channel, and a magnet. The spin-orbital coupling channel is coupled to, and is positioned between, the first contact line and second contact line. The magnet is coupled to the spin-orbital coupling channel and positioned between the first contact line and the second contact line. A resistance of the magnet and spin-orbital coupling channel is a unidirectional magnetoresistance. |
| FILED | Thursday, April 04, 2019 |
| APPL NO | 16/374925 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/16 (20130101) G11C 11/18 (20130101) G11C 11/161 (20130101) G11C 11/1659 (20130101) G11C 11/1673 (20130101) G11C 11/1675 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/22 (20130101) H01L 27/222 (20130101) H01L 27/224 (20130101) Original (OR) Class H01L 43/04 (20130101) H01L 43/08 (20130101) H01L 43/10 (20130101) Pulse Technique H03K 19/18 (20130101) H03K 19/177 (20130101) H03K 19/1776 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529820 | Chu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Kanin Chu (Nashua, New Hampshire); Pane Chane Chao (Nashua, New Hampshire); Carlton T Creamer (Brookline, New Hampshire) |
| ABSTRACT | A GaN on diamond wafer and method for manufacturing the same is provided. The method comprising: disposing a GaN device or wafer on a substrate, having a nucleation layer disposed between the substrate and a GaN layer; affixing the device to a handling wafer; removing the substrate and substantially all the nucleation layer; and bonding the GaN layer to a diamond substrate. |
| FILED | Wednesday, July 15, 2015 |
| APPL NO | 14/800387 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/0475 (20130101) H01L 21/2007 (20130101) H01L 21/2011 (20130101) H01L 21/6835 (20130101) H01L 21/76876 (20130101) H01L 23/3732 (20130101) H01L 27/1266 (20130101) H01L 29/778 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) H01L 29/66431 (20130101) Original (OR) Class H01L 2221/68327 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529909 | Dial et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Oliver Dial (Yorktown Heights, New York); Jay M. Gambetta (Yorktown Heights, New York); Douglas T. McClure, III (Rye, New York); Matthias Steffen (Cortlandt Manor, New York) |
| ABSTRACT | A technique relates a superconducting microwave cavity. An array of posts has different heights in the cavity, and the array supports a localized microwave mode. The array of posts includes lower resonant frequency posts and higher resonant frequency posts. The higher resonant frequency posts are arranged around the lower resonant frequency posts. A first plate is opposite a second plate in the cavity. One end of the lower resonant frequency posts is positioned on the second plate so as to be electrically connected to the second plate. Another end of the lower resonant frequency posts in the array is open so as not to form an electrical connection to the first plate. Qubits are connected to the lower resonant frequency posts in the array of posts, such that each of the qubits is physically connected to one or two of the lower resonant frequency posts in the array of posts. |
| FILED | Wednesday, April 04, 2018 |
| APPL NO | 15/945281 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) G06N 20/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/14 (20130101) H01L 39/24 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529938 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Hong Koo Kim (Wexford, Pennsylvania); Daud Hasan Emon (Hillsboro, Oregon) |
| ABSTRACT | Various light emitting diode device embodiments that include emissive material elements, e.g., core-shell quantum dots, that are either (i) provided in nanoscale holes provided in an insulating layer positioned between an electron supply/transport layer and a hole supply/transport layer, or (ii) provided on a suspension layer positioned above and covering a nanoscale hole in such an insulating layer. Also, various methods of making such light emitting diode devices, including lithographic and non-lithographic methods. |
| FILED | Wednesday, May 16, 2018 |
| APPL NO | 15/980868 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/50 (20130101) Original (OR) Class H01L 51/56 (20130101) H01L 51/0096 (20130101) H01L 51/502 (20130101) H01L 51/5004 (20130101) H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 51/5096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530127 | Deppe |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Dennis G. Deppe (Oviedo, Florida) |
| ABSTRACT | A semiconductor vertical light source includes upper and lower mirrors with an active region in between, an inner mode confinement region, and an outer current blocking region that includes a common epitaxial layer including an epitaxially regrown interface between the active region and upper mirror. A conducting channel including acceptors is in the inner mode confinement region. The current blocking region includes a first impurity doped region with donors between the epitaxially regrown interface and active region, and a second impurity doped region with acceptors between the first doped region and lower mirror. The outer current blocking region provides a PNPN current blocking region that includes the upper mirror or a p-type layer, first doped region, second doped region, and lower mirror or an n-type layer. The first and second impurity doped region force current flow into the conducting channel during normal operation of the light source. |
| FILED | Thursday, June 21, 2018 |
| APPL NO | 16/014305 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/183 (20130101) H01S 5/305 (20130101) H01S 5/323 (20130101) H01S 5/2018 (20130101) H01S 5/2054 (20130101) H01S 5/2059 (20130101) H01S 5/3013 (20130101) H01S 5/3054 (20130101) H01S 5/3201 (20130101) H01S 5/18308 (20130101) Original (OR) Class H01S 5/18322 (20130101) H01S 5/18327 (20130101) H01S 5/18358 (20130101) H01S 2301/166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530294 | Hirst et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America as represented by the Secretary of Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Louise C. Hirst (Hyattsville, Maryland); Michael K. Yakes (Alexandria, Virginia); Cory D. Cress (Alexandria, Virginia); Phillip Jenkins (Cleveland Heights, Ohio); Jeffrey H. Warner (Arbutus, Maryland); Kenneth Schmieder (Alexandria, Virginia); Robert J. Walters (Alexandria, Virginia) |
| ABSTRACT | Photovoltaic (PV) device comprising an ultra-thin radiation-tolerant PV absorber mounted on a flexible film having an embedded persistent phosphor and having a plurality of interdigitated top and bottom contacts on the top of the PV absorber. The PV absorber is ultra-thin, e.g., typically having a thickness of 300 nm or less for a III-V-based absorber. The phosphor absorbs some of the photons incident on the device and then discharges them for use by the device in generating electrical power during times when the device is not illuminated by the sun. |
| FILED | Friday, June 02, 2017 |
| APPL NO | 15/611878 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/055 (20130101) H01L 31/0304 (20130101) H01L 31/0543 (20141201) H01L 31/0547 (20141201) H01L 31/02366 (20130101) H01L 31/03926 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 30/20 (20141201) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530337 | Nguyen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Clark T.-C. Nguyen (Oakland, California); Thura Lin Naing (Berkeley, California); Tristan O. Rocheleau (Berkeley, California) |
| ABSTRACT | Active feedback is used with two electrodes of a four-electrode capacitive-gap transduced wine-glass disk resonator to enable boosting of an intrinsic resonator Q and to allow independent control of insertion loss across the two other electrodes. Two such Q-boosted resonators configured as parallel micromechanical filters may achieve a tiny 0.001% bandwidth passband centered around 61 MHz with only 2.7 dB of insertion loss, boosting the intrinsic resonator Q from 57,000, to an active Q of 670,000. The split capacitive coupling electrode design removes amplifier feedback from the signal path, allowing independent control of input-output coupling, Q, and frequency. Controllable resonator Q allows creation of narrow channel-select filters with insertion losses lower than otherwise achievable, and allows maximizing the dynamic range of a communication front-end without the need for a variable gain low noise amplifier. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/209442 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/29 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/64 (20130101) H03H 9/465 (20130101) H03H 9/525 (20130101) H03H 9/2426 (20130101) H03H 9/2436 (20130101) H03H 11/0466 (20130101) Original (OR) Class H03H 11/0472 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530380 | Beuville et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Eric J. Beuville (Goleta, California); Matthew T. Kuiken (Goleta, California); Joshua J. Cantrell (Santa Barbara, California); Mark A. Massie (Solvang, California) |
| ABSTRACT | An image detector includes an array of detector unit cells including a plurality of unit cells and a plurality of single slope analog to digital converters (SSADCs). Each of the plurality of SSADCs is coupled to an output of a different one of the unit cells. Each each of the plurality of SSADCs includes: a comparator having a positive input and a negative input and a comparator output, the comparator being contained in a first layer; and a counter coupled to the comparator output and contained in a second layer. The counter is electrically coupled to the comparator with a through a silicon via. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 15/964511 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/56 (20130101) H03M 1/123 (20130101) H03M 1/144 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530384 | Chakrabarti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustee of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Anandaroop Chakrabarti (New York, New York); Harish Krishnaswamy (New York, New York) |
| ABSTRACT | Circuits comprising: digital-to-amplitude converter (DAC), comprising: binary weighted switching transistors (BWSTs), each having gate coupled to amplitude control bit ACB, and wherein the drain of each of the BWSTs are connected together and wherein the source of each of the BWSTs are connected together; transistor M1 having gate coupled to input signal and first bias voltage BV1 and source coupled to the drains of the BWSTs; transistor M2 having gate coupled to BV2 and source coupled to the drain of M1; transistor M3 having gate coupled to BV3 and source coupled to the drain of M2; transistor having gate coupled to BV4, source coupled to the drain of M3; and inverter having input coupled to another ACB and having output coupled to the output of the DAC and the drain of M4. |
| FILED | Monday, January 09, 2017 |
| APPL NO | 15/401547 |
| ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Control of Amplification H03G 3/001 (20130101) H03G 3/3036 (20130101) Coding; Decoding; Code Conversion in General H03M 1/66 (20130101) Original (OR) Class H03M 1/78 (20130101) H03M 1/745 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/03878 (20130101) H04L 27/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10531554 | Imhof |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Utah State University Research Foundation (North Logan, Utah) |
| ASSIGNEE(S) | Utah State University Space Dynamics Laboratory (North Logan, Utah) |
| INVENTOR(S) | Eric Imhof (Calabasas, California) |
| ABSTRACT | A three-dimensional magneto-optical trap (3D GMOT) configured to trap a cold-atom cloud is disclosed. The 3D GMOT includes a single input light beam having its direction along a first axis, an area along a second and third axis that are both normal to the first axis, and a substantially flat input light beam intensity profile extending across its area. The 3D GMOT may also include a circular, diffraction-grating surface positioned normal to the first axis and having closely adjacent grooves arranged concentrically around a gap formed in its center. The circular, diffraction-grating surface is configured to diffract first-order light beams that intersect within an intersection region that lies directly above the gap and suppresses reflections and diffractions of all other orders. The 3D GMOT may further include a quadrupole magnetic field with its magnitude being zero within the intersection region. |
| FILED | Friday, March 01, 2019 |
| APPL NO | 16/290521 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/4233 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 3/02 (20130101) H05H 3/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10531555 | Haynes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Aisha Haynes (Piscataway, New Jersey); Calvin Lim (Elizabeth, New Jersey) |
| ABSTRACT | A tungsten trioxide thermal shield for electronic components in a gun launched munition includes tungsten trioxide grains suspended in a binder. The thermal shield is made such that a tungsten trioxide rich layer is adjacent the electronic component and a binder rich layer opposes the tungsten trioxide rich layer. |
| FILED | Wednesday, March 22, 2017 |
| APPL NO | 15/465728 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 19/02 (20130101) B32B 33/00 (20130101) B32B 2307/306 (20130101) B32B 2571/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/32 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/495 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0201 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 10524663 | Boppart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Stephen A. Boppart (Champaign, Illinois); Paul Scott Carney (Champaign, Illinois); Nathan Shemonski (Urbana, Illinois) |
| ABSTRACT | Methods and apparatus for assessing and correcting phase variations and motion artifacts in a coherent tomogram of a sample. Coherent techniques are used scan a broadband optical beam across a sample in a specified scan pattern and to acquire a cube of complex data constituting a full tomogram. Generalized motion of the sample is then quantified based at least on a phase variation measured during the course of scanning the broadband optical beam in the specified scan pattern. Generalized motion includes both actual motion and apparent motion due to organized variation of some physical parameter such as temperature. Intensity structure of speckle imaged during the course of coherently acquiring the full tomograpm may be used to correct for motion of the sample in a plane transverse to a depth axis along the incident beam. |
| FILED | Friday, June 17, 2016 |
| APPL NO | 15/185410 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) Original (OR) Class A61B 5/7207 (20130101) A61B 2576/00 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02077 (20130101) G01B 9/02091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524664 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); OPTICENT, INC. (Deerfield, Illinois) |
| INVENTOR(S) | Wenzhong Liu (Evanston, Illinois); Lian Duan (Evanston, Illinois); Hao F. Zhang (Deerfield, Illinois); Kieren J. Patel (Santa Monica, California); Hao Li (Evanston, Illinois); Biqin Dong (Evanston, Illinois); Amani A. Fawzi (Chicago, Illinois) |
| ABSTRACT | The present disclosure provides systems and methods for the determining a rate of change of one or more analyte concentrations in a target using non invasive non contact imaging techniques such as OCT. Generally, OCT data is acquired and optical information is extracted from OCT scans to quantitatively determine a flow rate of fluid in the target; angiography is also performed using one or more fast scanning methods to determine a concentration of one or more analytes. Both calculations can provide a means to determine a change in rate of an analyte over time. Example methods and systems of the disclosure may be used in assessing metabolism of a tissue, where oxygen is the analyte detected, or other functional states, and be generally used for the diagnosis, monitoring and treatment of disease. |
| FILED | Monday, May 01, 2017 |
| APPL NO | 15/583615 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/0066 (20130101) Original (OR) Class A61B 5/145 (20130101) A61B 5/489 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10016 (20130101) G06T 2207/10101 (20130101) G06T 2207/30104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524686 | Ellingson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Benjamin M. Ellingson (Los Angeles, California) |
| ABSTRACT | Methods for quickly estimating apparent diffusion coefficient probability density functions (ADC PDFs) for each image voxel are provided using a “diffusion reproducibility evaluation and measurement” (DREAM) magnetic resonance sequence. Non-diffusion-weighted (reference) images collected simultaneously have blood oxygenation level dependent (BOLD) sensitivity that can be used for resting-state fMRI data to measure functional connectivity, an unbiased parameter reflecting neurological integrity. ADC coefficient of variation (ADC CV) measurements can be used to isolate and label regions of non-enhancing tumor and predict future enhancement independent of FLAIR, T2, or average ADC maps. Functional diffusion mapping (fDMs) using voxel-wise changes in ADC PDFs can be used to spatially visualize and statistically quantify response to treatment. Additionally, the temporal (time-resolved) diffusivity information can be used for real-time MR thermometry, which is useful for cancer treatment monitoring, and for microperfusion quantification, and tumor/tissue characterization. |
| FILED | Tuesday, December 01, 2015 |
| APPL NO | 14/956149 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/7207 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/561 (20130101) G01R 33/56341 (20130101) G01R 33/56518 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525013 | Farokhzad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Omid Farokhzad (Waban, Massachusetts); Jun Wu (Boston, Massachusetts); Lili Zhao (Boston, Massachusetts) |
| ABSTRACT | Cationic polymers are provided for delivering anionic active agents, preferably in the form or nanoparticles and other nanostructures. The polymer can be a polycation homopolymer or a copolymer containing a polycation block. The polycations and polycation containing polymers can contain dicarboxylic acid ester units and units of (α-amino acid)-α,ω-alkylene diester units. The nanoparticles can contain high loadings of anionic active agents, with sustained release of the active agents. Methods of making the polycations and polycation containing polymers are provided. Methods of making the nanoparticles and formulating them for administration to an individual in need thereof are also provided. |
| FILED | Wednesday, July 11, 2018 |
| APPL NO | 16/033040 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5073 (20130101) A61K 9/5078 (20130101) A61K 9/5153 (20130101) Original (OR) Class A61K 9/5192 (20130101) A61K 38/28 (20130101) A61K 38/38 (20130101) A61K 38/385 (20130101) A61K 47/60 (20170801) A61K 47/593 (20170801) A61K 47/645 (20170801) A61K 47/6931 (20170801) A61K 47/6937 (20170801) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525019 | Gudas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Lorraine J Gudas (New York, New York); Yannick Benoit (Ontario, Canada); Ronald Perez (Somerset, New Jersey); Xiao-Han Tang (Staten Island, New York); Steven Trasino (Brooklyn, New York) |
| ABSTRACT | This invention relates to pharmaceutical composition and methods of using vitamin A and/or RARβ agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency. |
| FILED | Tuesday, June 05, 2018 |
| APPL NO | 16/000003 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/07 (20130101) Original (OR) Class A61K 31/192 (20130101) A61K 31/203 (20130101) A61K 31/426 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525024 | Kadam |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); KENNEDY KRIEGER INSTITUTE, INC. (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Kennedy Krieger Institute, Inc. (Baltimore, Maryland) |
| INVENTOR(S) | Shilpa D. Kadam (Pikesville, Maryland) |
| ABSTRACT | The present invention relates to the field of seizures. More specifically, the present invention provides compositions and methods for treating refractory seizures in neonates. In one embodiment, the method comprises the steps of (a) administering to the patient an amount of a KCC2 agonist and/or trkB antagonist effective to restore KCC2 expression to normal physiological levels; and (b) administering to the patient an effective amount of an anti-seizure medication. |
| FILED | Friday, August 14, 2015 |
| APPL NO | 15/504141 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2207/20 (20130101) A01K 2207/30 (20130101) A01K 2267/0356 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/55 (20130101) A61K 31/196 (20130101) Original (OR) Class A61K 31/196 (20130101) A61K 31/501 (20130101) A61K 31/501 (20130101) A61K 31/515 (20130101) A61K 31/515 (20130101) A61K 31/553 (20130101) A61K 31/553 (20130101) A61K 31/4015 (20130101) A61K 31/4015 (20130101) A61K 31/4166 (20130101) A61K 31/4166 (20130101) A61K 38/08 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525047 | Bieberich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| INVENTOR(S) | Charles J. Bieberich (Brookeville, Maryland); Xiang Li (Baltimore, Maryland); Tejashree Joglekar (Savage, Maryland) |
| ABSTRACT | The present invention provides for a method of treating cancer and/or reducing proliferation of cancer cells, the method comprising administering to a subject in need of such treatment a composition comprising a PIM kinase inhibitor that exhibits changes of mRNA splicing in combination with a compound that modulates/inhibits activity of an RNA splicing factor protein. Further, changes in splicing of mRNAs and phosphorylation of RNA splicing factors can be used as biomarkers for patient responsiveness to anti-PIM treatment and also suggest effective combinatorial therapies, including synergistic combination. |
| FILED | Wednesday, March 22, 2017 |
| APPL NO | 16/082325 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/365 (20130101) A61K 31/454 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525048 | Min et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York); St. Jude Children's Research Hospital (Memphis, Tennessee) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York); St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Jaeki Min (Memphis, Tennessee); Daniel C. Scott (Marion, Arkansas); Deepak Bhasin (Cordova, Tennessee); Brenda A. Schulman (Memphis, Tennessee); Bhuvanesh Singh (Old Westbury, New York); Jared T. Hammill (Memphis, Tennessee); R. Kiplin Guy (Memphis, Tennessee) |
| ABSTRACT | In one aspect, the invention relates to substituted 1-phenyl-3-(piperidin-4-yl)urea analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the DCN1-UBC12 interaction inhibitors of DCN1-mediated cullin-RING ligase activity, methods of making same, pharmaceutical compositions comprising same, methods of treating disorders using the disclosed compounds and compositions, methods of treating disorders associated with a DCN1-UBC12 interaction dysfunction, methods of treating disorders associated with a DCN1-mediated cullin-RING ligase activity dysfunction, methods of male contraception comprising the disclosed compounds and compositions, and kits comprising the disclosed compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Monday, September 19, 2016 |
| APPL NO | 15/760560 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/437 (20130101) A61K 31/451 (20130101) A61K 31/454 (20130101) A61K 31/506 (20130101) A61K 31/4525 (20130101) A61K 31/4545 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/16 (20180101) A61P 31/04 (20180101) A61P 31/12 (20180101) Heterocyclic Compounds C07D 211/58 (20130101) C07D 401/04 (20130101) C07D 401/06 (20130101) C07D 401/12 (20130101) C07D 405/06 (20130101) C07D 405/12 (20130101) C07D 409/14 (20130101) C07D 417/04 (20130101) C07D 417/06 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525050 | Ablordeppey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida A and M University (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida A and M University (Tallahassee, Florida) |
| INVENTOR(S) | Seth Y. Ablordeppey (Tallahassee, Florida) |
| ABSTRACT | Derivatives of 1,2,3,4-tetrahydroisoquinoline (THIQ) having the general formula A-(CH2)n—B are provided, wherein A is THIQ or a substituted derivative thereof and B is an aryl, cycloalkylaryl, or cycloalkyl group, wherein A and B are linked to each other by an alkyl or substituted alkyl chain. The compounds are useful as selective ligands (agonists or antagonists) of central nervous system receptors, and in particular of the seratonin receptors. The compounds or their salts can be formulated into pharmaceutical in need thereof by any route of administration suitable for a desired treatment protocol and especially for the treatment of psychiatric disorders. |
| FILED | Thursday, January 04, 2018 |
| APPL NO | 15/861750 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/4725 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525056 | Hergenrother |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Paul J. Hergenrother (Champaign, Illinois) |
| ABSTRACT | The invention provides compounds and compositions useful for the modulation of certain enzymes. The compounds and compositions can induce of cell death, particularly cancer cell death. The invention also provides methods for the synthesis and use of the compounds and compositions, including the use of compounds and compositions in therapy for the treatment of cancer and selective induction of apoptosis in cells. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/037812 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) Original (OR) Class Heterocyclic Compounds C07D 295/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525070 | Andrews et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina); CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Nancy C. Andrews (Durham, North Carolina); Wenjing Xu (Durham, North Carolina); Anthony A. Sauve (New Rochelle, New York) |
| ABSTRACT | Disclosed herein is a method for treating heart failure in a subject in need thereof. The method includes administering a therapeutically effective amount of nicotinamide riboside to the subject. The heart failure may be associated with iron deficiency. The method may also include administering iron to the subject. |
| FILED | Wednesday, February 10, 2016 |
| APPL NO | 15/550150 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/706 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525071 | Wurtman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Richard J. Wurtman (Boston, Massachusetts); Ingrid Richardson (Newton, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETS INSTITUE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Richard J. Wurtman (Boston, Massachusetts); Ingrid Richardson (Newton, Massachusetts) |
| ABSTRACT | This invention provides methods of increasing or enhancing the synthesis and levels of phospholipids, synapses, synaptic proteins, and synaptic membranes by a neural cell or brain cell; methods of treating a subject with a memory disorder, memory impairment, neurological disorder, or brain disease or disorder, comprising administering to the subject a composition comprising an omega-3 fatty acid, an omega-6 fatty acid, uridine, a metabolic precursor thereof, or a combination thereof. |
| FILED | Tuesday, May 23, 2006 |
| APPL NO | 11/920914 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/14 (20130101) A61K 31/14 (20130101) A61K 31/202 (20130101) A61K 31/202 (20130101) A61K 31/7072 (20130101) Original (OR) Class A61K 31/7072 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/28 (20180101) A61P 43/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525075 | Ramunas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | John Ramunas (Menlo Park, California); Eduard Yakubov (Houston, Texas); Helen M. Blau (Menlo Park, California); John Cooke (Houston, Texas) |
| ABSTRACT | Compounds and compositions for the transient expression of exogenous telomerase activity in a cell are provided. The compounds and compositions, which relate to a ribonucleic acid coding for a telomerase reverse transcriptase, are useful in the extension of telomeres in cells needing such treatment. Such cells include, for example, cells that contain shortened telomeres and cells from subjects that may benefit from telomere extension, for example subjects that suffer from, or are at risk of suffering from, age-related or other illnesses. Also provided are methods of extending telomeres through the administration of the provided compounds and compositions to animal cells, either in vitro or in vivo, and kits including the compounds or compositions and instructions for use. |
| FILED | Saturday, February 22, 2014 |
| APPL NO | 14/187265 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Original (OR) Class A61K 38/45 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1276 (20130101) C12N 15/52 (20130101) Enzymes C12Y 207/07049 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525085 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Douglas H. Smith (Boothwyn, Pennsylvania); Daniel Kacy Cullen (Media, Pennsylvania); John A. Wolf (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention relates to methods and compositions for maintaining the pro-regenerative capacity of distal nerve segments following nerve injury. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/863278 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525086 | Tilly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHEASTERN UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Jonathan L. Tilly (Windham, New Hampshire); Dori C. Woods (Londonderry, New Hampshire) |
| ABSTRACT | The present technology provides for methods for generation and isolation of granulosa cells and/or granulosa cell precursors from multi-potent cells, wherein the granulosa cells and/or granulosa cell precursors are useful in methods for growth and maturation of follicles or follicle-like structures. Additionally, the present technology also provides for methods of increasing steroidal hormones in a subject in need thereof. |
| FILED | Thursday, March 27, 2014 |
| APPL NO | 15/126680 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/54 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0605 (20130101) C12N 5/0609 (20130101) C12N 2502/025 (20130101) C12N 2506/02 (20130101) C12N 2510/00 (20130101) C12N 2740/16043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525101 | Vandenbark et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Arthur A. Vandenbark (Portland, Oregon); Gil Benedek (Portland, Oregon); Roberto Meza-Romero (Beaverton, Oregon) |
| ABSTRACT | Recombinant polypeptides, pharmaceutical compositions comprising recombinant polypeptides, and methods of treating autoimmune and/or inflammatory diseases using the pharmaceutical compositions are disclosed. The polypeptides are based upon the trimerization and/or MIF binding domains of CD74. |
| FILED | Friday, October 21, 2016 |
| APPL NO | 15/331612 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1774 (20130101) Original (OR) Class Peptides C07K 14/70539 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525108 | Friedlander et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University Of Pittsburgh Of The Commonwealth System Of Higher Education (Pittsburgh, Pennsylvania); WASHINGTON UNIVERSiTY (St. Louis, Missouri) |
| ASSIGNEE(S) | University of Pittsburgh Of The Commonwealth System Of Higher Education (Pittsburgh, Pennsylvania); WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| INVENTOR(S) | Robert Friedlander (Pittsburgh, Pennsylvania); Hiroko Yano (Richmond Heights, Missouri) |
| ABSTRACT | The present invention relates to methods of inhibiting neurodegeneration in a subject suffering from or genetically at risk and/or destined to develop Huntington's Disease comprising increasing, in neurons of the subject, the activity of the TIM23 mitochondrial protein import complex. |
| FILED | Monday, October 17, 2016 |
| APPL NO | 15/295538 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/45 (20130101) Original (OR) Class A61K 38/45 (20130101) A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1205 (20130101) C12N 15/62 (20130101) Enzymes C12Y 207/11001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525119 | Goldstein |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Boston Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Boston Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Richard N. Goldstein (Cambridge, Massachusetts) |
| ABSTRACT | Cold spot genes of S. pneumoniae are disclosed that encode surface proteins that are universally conserved among known strains and have exceptionally low incidence of allelic variation. Cold spot polypeptides encoded by the genes that are antigenic on the S. pneumoniae cells on which they are expressed are candidates for immunogenic compositions capable of eliciting antibodies able to react with all or nearly all strains of S. pneumoniae, thus providing an improvement over currently available S. pneumoniae vaccines that protect inoculated individuals against a maximum of about 23 of the 94 or so known serotypes of S. pneumonia. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 15/939850 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/092 (20130101) Original (OR) Class A61K 2039/575 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525120 | Stinchcomb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Takeda Vaccines, Inc. (Deerfield, Illinois) |
| ASSIGNEE(S) | TAKEDA VACCINES, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Dan Stinchcomb (Fort Collins, Colorado); Jorge E. Osorio (Mount Horeb, Wisconsin); O'Neil Wiggan (Fort Collins, Canada) |
| ABSTRACT | Embodiments herein relate to compositions of and methods for live viruses. In certain embodiments, a live, attenuated virus composition includes, but is not limited to, one or more live, attenuated viruses and compositions to reduce inactivation and/or degradation of the live, attenuated virus. In other embodiments, the live, attenuated virus composition may be a vaccine composition. In yet other compositions, a live, attenuated virus composition may include at least one carbohydrate, at least one protein and at least one high molecular weight surfactants for reducing inactivation and/or degradation of the live, attenuated virus. |
| FILED | Friday, July 22, 2016 |
| APPL NO | 15/194297 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 47/26 (20130101) A61K 47/36 (20130101) A61K 47/42 (20130101) A61K 2039/70 (20130101) A61K 2039/5254 (20130101) A61K 2039/55555 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 2650/58 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) C08L 2203/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10051 (20130101) C12N 2710/10061 (20130101) C12N 2710/24151 (20130101) C12N 2710/24161 (20130101) C12N 2760/16051 (20130101) C12N 2760/16061 (20130101) C12N 2760/18411 (20130101) C12N 2770/24134 (20130101) C12N 2770/24151 (20130101) C12N 2770/24161 (20130101) C12N 2770/36151 (20130101) C12N 2770/36161 (20130101) Technologies for Adaptation to Climate Change Y02A 50/39 (20180101) Y02A 50/386 (20180101) Y02A 50/388 (20180101) Y02A 50/394 (20180101) Y02A 50/396 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525126 | Silhavy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Thomas J. Silhavy (Belle Mead, New Jersey); Marcin Grabowicz (Princeton, New Jersey); Daniel Kahne (Brookline, Massachusetts); Matthew Lebar (Mandeville, Louisiana); Dorothee Andres (Potsdam, Germany) |
| ABSTRACT | The present disclosure generally relates to genetic engineering of bacteria. More particularly, the present disclosure describes genetic engineering of E. coli to create mutant O-antigen ligase, as well as novel lipopolysaccharide molecules resulting from that genetic engineering. Methods for using those novel molecules are also described. |
| FILED | Thursday, May 04, 2017 |
| APPL NO | 15/586781 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Original (OR) Class A61K 2039/55516 (20130101) A61K 2039/55572 (20130101) A61K 2039/55583 (20130101) A61K 2039/55594 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 13/06 (20130101) C07H 15/04 (20130101) Peptides C07K 4/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/00 (20130101) C12N 9/93 (20130101) C12N 15/04 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525269 | Kass et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | David Kass (Columbia, Maryland); Gordon Tomaselli (Lutherville, Maryland); Jonathan Kirk (Baltimore, Maryland) |
| ABSTRACT | The invention provides methods related to improving heart function. |
| FILED | Tuesday, November 22, 2016 |
| APPL NO | 15/359041 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/365 (20130101) A61N 1/3627 (20130101) Original (OR) Class A61N 1/3682 (20130101) A61N 1/3684 (20130101) A61N 1/3688 (20130101) A61N 1/36507 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525285 | Friedman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Integrated Sensors, LLC (Ottawa Hills, Ohio) |
| ASSIGNEE(S) | Integrated Sensors, LLC (Ottawa Hills, Ohio) |
| INVENTOR(S) | Peter S. Friedman (Ottawa Hills, Ohio) |
| ABSTRACT | A transmissive ionizing-radiation beam monitoring system includes an enclosure structure including an entrance window and an exit window to an incident ionizing-radiation beam, where the entrance window and the exit window are highly transmissive. The system further includes a thin scintillator within the enclosure structure that is directly in an incident ionizing-radiation beam path and transmissive to the incident radiation beam and an ultraviolet (“UV”) illumination source within the enclosure structure facing the scintillator for internal system calibration. Embodiments further include a UV photosensor within the enclosure structure positioned to monitor and calibrate the UV illumination source and a machine vision camera within the enclosure structure that includes a lens which views the scintillator through a close proximity mirror including a folded optical axis system located to a side of the scintillator. |
| FILED | Thursday, August 01, 2019 |
| APPL NO | 16/529200 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101) A61N 5/1045 (20130101) A61N 5/1048 (20130101) A61N 5/1049 (20130101) A61N 5/1064 (20130101) A61N 5/1067 (20130101) Original (OR) Class A61N 5/1077 (20130101) A61N 2005/1059 (20130101) A61N 2005/1087 (20130101) Measurement of Nuclear or X-radiation G01T 1/29 (20130101) G01T 1/1612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526278 | Blackwell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Helen Blackwell (Middleton, Wisconsin); Daniel Manson (Madison, Wisconsin) |
| ABSTRACT | Modulation of quorum sensing in Gram-negative bacteria, particularly strains of Pseudomonas which form biofilms, by compounds including those of formula I and formula II: where: AR is optionally substituted phenyl, cycloalkyl or cycloalkenyl or heterocyclic, and R1 is optionally substituted alkyl, alkenyl, alkoxyalkyl, or alkylthioalkyl or alkyl substituted at the omega position with optionally substituted phenyl, cyclohexyl or cyclohexenyl. In particular compounds inhibit quorum sensing and biofilm formation. Pharmaceutical compositions for treatment of bacterial infections and methods of treatment of such infections are provided. |
| FILED | Thursday, October 11, 2018 |
| APPL NO | 16/157855 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic or Carbocyclic Compounds C07C 235/74 (20130101) Original (OR) Class Heterocyclic Compounds C07D 307/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526289 | Silverman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Richard B. Silverman (Winnetka, Illinois); Yinan Zhang (Lexington, Kentucky) |
| ABSTRACT | The present invention relates to the identification of compounds and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the provided compounds. |
| FILED | Tuesday, August 22, 2017 |
| APPL NO | 15/683131 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Heterocyclic Compounds C07D 231/18 (20130101) Original (OR) Class C07D 231/20 (20130101) C07D 401/06 (20130101) C07D 403/06 (20130101) C07D 471/04 (20130101) C07D 498/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526291 | Schönbrunn et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| INVENTOR(S) | Ernst Schönbrunn (Tampa, Florida); Nicholas J. Lawrence (Tampa, Florida); Harshani R. Lawrence (Tampa, Florida); Gary W. Reuther (Tampa, Florida) |
| ABSTRACT | Disclosed herein are compounds that are inhibitors of BRD4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BRD4 are also disclosed. In certain aspects, disclosed are compounds of Formula I-IV. |
| FILED | Monday, October 22, 2018 |
| APPL NO | 16/166611 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 239/48 (20130101) Original (OR) Class C07D 239/70 (20130101) C07D 239/95 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 491/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526298 | Beaton et al. |
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| FUNDED BY |
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| APPLICANT(S) | EPIGEN BIOSCIENCES, INC. (San Diego, California) |
| ASSIGNEE(S) | EPIGEN BIOSCIENCES, INC. (San Diego, California) |
| INVENTOR(S) | Graham Beaton (San Diego, California); Fabio C. Tucci (San Diego, California); Satheesh B. Ravula (San Diego, California); Chandravadan R. Shah (San Diego, California); Hiep Luu (San Marcos, California) |
| ABSTRACT | Heterocyclic compounds are described that are lysophosphatidic acid receptor ligands that are useful in the treatment of lysophosphatidic acid receptor-dependent diseases and conditions, including but not limited to diseases involving fibrosis, such as fibrosis of the heart, kidney, liver and lung, and scleroderma; inflammatory diseases such as diabetic nephropathy and nonalcoholic steatohepatitis (NASH); ocular diseases such as diseases involving retinal degeneration; nerve diseases such as pruritus and pain. |
| FILED | Monday, June 18, 2018 |
| APPL NO | 16/010755 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/415 (20130101) Heterocyclic Compounds C07D 231/38 (20130101) C07D 231/52 (20130101) C07D 233/88 (20130101) C07D 239/42 (20130101) C07D 261/14 (20130101) Original (OR) Class C07D 263/48 (20130101) C07D 401/04 (20130101) C07D 413/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526303 | Ye |
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| FUNDED BY |
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| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Keqiang Ye (Lilburn, Georgia) |
| ABSTRACT | In certain embodiments, the disclosure relates to 7,8-dihydoxyflavone and 7,8-substituted flavone derivatives, such as those described by formula provided herein, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing diseases or conditions related to BDNF and TrkB activity, such as psychiatric disorders, depression, post-traumatic stress disorder, and autism spectrum disorders, stroke, Rett syndrome, Parkinson's disease, and Alzheimer's disease by administering effective amounts of pharmaceutical compositions comprising compounds disclosed herein to a subject in need thereof. In certain embodiments, it is contemplated that the 7,8-substituted flavone derivatives disclosed herein are prodrugs of 7,8-dihydoxyflavone and analogs. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 15/905179 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) A61K 31/352 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 311/28 (20130101) C07D 311/30 (20130101) Original (OR) Class C07D 311/36 (20130101) C07D 311/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526307 | Piazza et al. |
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| FUNDED BY |
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| APPLICANT(S) | ADT Pharmaceuticals, LLC (Orange Beach, Alabama) |
| ASSIGNEE(S) | ADT Pharmaceuticals, LLC (Orange Beach, Alabama) |
| INVENTOR(S) | Gary A. Piazza (Daphne, Alabama); Xi Chen (Hoover, Alabama); Adam B. Keeton (Gardendale, Alabama); Michael R. Boyd (Orange Beach, Alabama) |
| ABSTRACT | Disclosed are compounds, for example, compounds of formula (I), (Formula (I) wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer. |
| FILED | Wednesday, December 16, 2015 |
| APPL NO | 15/537292 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/36 (20130101) A61K 31/36 (20130101) A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/44 (20130101) A61K 31/44 (20130101) A61K 31/341 (20130101) A61K 31/341 (20130101) A61K 31/401 (20130101) A61K 31/445 (20130101) A61K 31/445 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 233/58 (20130101) C07C 235/32 (20130101) C07C 237/20 (20130101) C07C 2601/02 (20170501) C07C 2602/08 (20170501) Heterocyclic Compounds C07D 207/14 (20130101) C07D 207/337 (20130101) C07D 211/56 (20130101) C07D 213/24 (20130101) C07D 213/75 (20130101) C07D 235/30 (20130101) C07D 307/38 (20130101) C07D 307/52 (20130101) C07D 307/54 (20130101) C07D 317/64 (20130101) Original (OR) Class C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526309 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Xiaodong Wang (Chapel Hill, North Carolina); Dehui Zhang (Chapel Hill, North Carolina); Dmitri Kireev (Chapel Hill, North Carolina); Henry Shelton Earp, III (Chapel Hill, North Carolina) |
| ABSTRACT | This invention is in the area of improved therapeutic combinations for and methods of treating selected cancers using selected pyrimidine compounds having pan-TAM or Mer/Axl dual receptor tyrosine kinase inhibitory activity in combination with immune checkpoint inhibitors. In one aspect, an improved treatment for select cancers is disclosed using selected pyrimidine compounds described herein in combination with an immune checkpoint inhibitor, for example, a cytotoxic T-lymphocyte-associated protein 4 (CTLA4) inhibitor, a programmed cell death protein 1 (PD1) inhibitor, or a programmed death-ligand 1 (PDL-1) inhibitor, or combination thereof. |
| FILED | Friday, September 30, 2016 |
| APPL NO | 15/765168 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 239/48 (20130101) C07D 401/04 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 405/14 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526322 | Cerione et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York); ITHACA COLLEGE (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); Ithaca College (Ithaca, New York) |
| INVENTOR(S) | Richard Cerione (Ithaca, New York); Kristin Cerione (Ithaca, New York); Clint Stalnecker (Ithaca, New York); Scott Ulrich (Brooktondale, New York) |
| ABSTRACT | The present invention relates generally to glutaminase inhibitors of Formula I, Formula II, or Formula III, as well as pharmaceutical compounds containing them and methods of their use. |
| FILED | Saturday, December 05, 2015 |
| APPL NO | 15/533198 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 211/49 (20130101) C07C 211/52 (20130101) C07C 211/58 (20130101) C07C 211/59 (20130101) C07C 217/90 (20130101) C07C 237/40 (20130101) C07C 311/21 (20130101) C07C 311/37 (20130101) Heterocyclic Compounds C07D 207/16 (20130101) C07D 221/04 (20130101) C07D 221/06 (20130101) C07D 221/12 (20130101) C07D 221/18 (20130101) C07D 233/61 (20130101) C07D 277/82 (20130101) C07D 295/135 (20130101) C07D 401/10 (20130101) C07D 471/04 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/80 (20130101) C12N 9/96 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) Enzymes C12Y 305/01002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/98 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526328 | Resnick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Knopp Biosciences LLC (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Knopp Biosciences LLC (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Lynn Resnick (Pittsburgh, Pennsylvania); George T. Topalov (Pittsburgh, Pennsylvania); Charles A. Flentge (Mars, Pennsylvania); James S. Hale (Pittsburgh, Pennsylvania); David A. Mareska (McMurray, Pennsylvania); Justin K. Belardi (Pittsburgh, Pennsylvania); Kai Zhang (Wexford, Pennsylvania); Scott S. Harried (Sun Prairie, Wisconsin) |
| ABSTRACT | Compounds represented by formula 1 can be potent and/or partially selective for the Kv7.2/7.3 heteromultimer. They may be useful in treating disorders related to seizures, pain, neurotransmitter release, etc. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/124853 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526334 | Stoltz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Brian M. Stoltz (San Marino, California); Eric R. Welin (Pasadena, California); Scott C. Virgil (Pasadena, California); Pamela Tadross (Natick, Massachusetts); Gerit Maria Pototschnig (San Diego, California); Aurapat (Fa) Ngamnithiporn (Pasadena, California); Kenji Negoro (Ibaraki, Japan); Guillaume Lapointe (San Francisco, California); Max Klatte (Loerrach, Germany); Christopher Haley (Boston, Massachusetts); Christian Gruenanger (Mannheim, Germany); Emil Glibstrup (Copenhagen, Denmark); Christopher Gilmore (Natick, Massachusetts); Kevin McCormack Allan (Belmont, California) |
| ABSTRACT | (−)-Jorumycin, ecteinascidin 743, saframycin A and related compounds, methods of preparing the same, formulations comprising the compounds, and methods of treating proliferative diseases with the same are provided. |
| FILED | Wednesday, July 18, 2018 |
| APPL NO | 16/038968 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 471/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526359 | Oscarson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of California (Oakland, California); University College Dublin (Dublin, Ireland) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); University College Dublin (Dublin, Ireland) |
| INVENTOR(S) | Stefan Oscarson (Blackrock, Ireland); John Vincent Fahy (San Francisco, California); Shaopeng Yuan (San Francisco, California); Stephen Carrington (Roundwood, Ireland) |
| ABSTRACT | There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a thiosaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods. |
| FILED | Monday, November 27, 2017 |
| APPL NO | 15/822616 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/70 (20130101) A61K 31/702 (20130101) A61K 31/7016 (20130101) A61K 31/7028 (20130101) Heterocyclic Compounds C07D 309/10 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 5/04 (20130101) C07H 13/04 (20130101) C07H 15/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526368 | Wipf et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Peter Wipf (Pittsburgh, Pennsylvania); Marie-Celine Frantz (Seine Saint Denis, France) |
| ABSTRACT | Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation. |
| FILED | Wednesday, December 27, 2017 |
| APPL NO | 15/855598 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/454 (20130101) A61K 47/64 (20170801) Acyclic or Carbocyclic Compounds C07C 237/16 (20130101) Heterocyclic Compounds C07D 209/44 (20130101) C07D 209/46 (20130101) C07D 211/58 (20130101) C07D 211/94 (20130101) C07D 221/22 (20130101) C07D 279/06 (20130101) C07D 401/12 (20130101) C07D 417/12 (20130101) C07D 471/08 (20130101) Peptides C07K 5/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526375 | Tharakaraman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Kannan Tharakaraman (Arlington, Massachusetts); Rahul Raman (Waltham, Massachusetts); Akila Jayaraman (Waltham, Massachusetts); Nathan Wilson Stebbins (Cambridge, Massachusetts); Ram Sasisekharan (Lexington, Massachusetts) |
| ABSTRACT | The present invention provides, among other things, systems (e.g., comprising compositions and/or methods) for diagnosis, prophylaxis, treatment, prevention, and/or characterization of influenza transmission and/or infection. The present invention also provides methods for monitoring influenza variants for their potential to present a pandemic risk to humans. |
| FILED | Thursday, June 05, 2014 |
| APPL NO | 14/896062 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 16/1018 (20130101) C07K 2317/33 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/56983 (20130101) G01N 2333/11 (20130101) G01N 2469/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526391 | Baker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF NOTRE DAME DU LAC (Notre Dame, Indiana); University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | The University of Notre Dame du Lac (Notre Dame, Indiana); University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Brian Baker (Granger, Indiana); Lance Hellman (Granger, Indiana); Brian Pierce (Darnestown, Maryland); Zhiping Weng (Wellesley, Massachusetts) |
| ABSTRACT | Molecular constructs and dual recognition constructs having a sequence encoding a TCR affinity weakening motif, and DNA and RNA sequences corresponding thereto, are presented. Modified T-cells and other cells transformed with the molecular contracts express a modified TCR that imparts a reduction, in non-specific binding, -an enhancement of binding specificity and an enhancement of binding affinity for a target antigen, compared to non-transformed (wild-type, native) T-cells, are described. The modified TCRs possess an affinity enhancing motif and an affinity weakening motif. Methods of transforming cells and methods of using enriched populations of transformed cells, in the treatment of cancer and infections arid T-cell mediated pathologies are provided. The affinity weakening motif imparts a weakened interaction, of a TCR with major histocompatibility complex proteins, such as HLA proteins in humans. Soluble modified TCRs are also provided, Therapeutic preparations comprising modified T-cells, modified TCRs, and modified TCR-therapeutic agent-conjugates, are also provided. |
| FILED | Wednesday, July 22, 2015 |
| APPL NO | 15/327984 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/1774 (20130101) A61K 2035/124 (20130101) Peptides C07K 14/7051 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 15/86 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526395 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Michael F. Brown (Tucson, Arizona); Suchithranga Perera (Tucson, Arizona); Udeep Chawla (Tucson, Arizona) |
| ABSTRACT | A method for generating detergent-solubilized G-protein coupled receptors (GPCRs) in powdered form. The powdered GPCRs is storable at temperatures of −20° C. or lower and for durations of 365 days or longer without substantial loss of functionality of the GPCRs after rehydration as compared to a pre-frozen state. The method can maintain minimal detergent to protein ratio in molar concentrations. The method can further generate GPCRs with specific water or deuterium content as required in certain experiments, such as mass spectrometry, NMR spectroscopy, or quasi-elastic neutron scattering (QENS). |
| FILED | Friday, September 30, 2016 |
| APPL NO | 15/763052 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/723 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526400 | Maynard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); SYNTHETIC BIOLOGICS, INC. (Rockville, Maryland) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); SYNTHETIC BIOLOGICS, INC. (Rockville, Maryland) |
| INVENTOR(S) | Jennifer Maynard (Austin, Texas); Annalee Nguyen (Austin, Texas); Eduardo Padlan (Rockville, Maryland); Ellen Wagner (San Mateo, California) |
| ABSTRACT | The present invention relates to humanized antibodies which bind the pertussis toxin protein and their use as therapeutic agents. In particular, the present invention is directed to improved humanized 1B7 and 11E6 antibodies which bind the pertussis toxin protein. |
| FILED | Monday, June 25, 2018 |
| APPL NO | 16/016890 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/40 (20130101) A61K 45/06 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/1225 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/24 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526401 | Muir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Tom W. Muir (Princeton, New Jersey); Miquel Vila-Perello (Princeton, New Jersey); Zhihua Liu (Plainsborough, New Jersey); Neel H. Shah (Princeton, New Jersey) |
| ABSTRACT | Disclosed herein are split inteins, fused proteins of split inteins, and methods of using split inteins to efficiently purify and modify proteins of interest. |
| FILED | Friday, November 10, 2017 |
| APPL NO | 15/809440 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/195 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2319/50 (20130101) C07K 2319/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) C12P 21/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526418 | Shi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Yuguang Shi (Hershey, Pennsylvania) |
| ABSTRACT | Compositions of modulators of acyl-CoA lysocardiolipin acyltransferase 1 (ALCAT1) expression, function or activity are provided. In particular, inhibitors of ALCAT1 are useful in treating metabolic diseases, cardiac diseases and, in general diseases associated with mitochondrial dysfunction. Assays for identification of novel ALCAT1 modulators are provided. |
| FILED | Monday, July 17, 2017 |
| APPL NO | 15/651758 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/46 (20130101) A61K 38/1709 (20130101) A61K 39/3955 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/40 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 2310/111 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 306/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526573 | Ding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiaoyun Ding (Cambridge, Massachusetts); Armon R. Sharei (Watertown, Massachusetts); Robert S. Langer (Newton, Massachusetts); Klavs F. Jensen (Lexington, Massachusetts) |
| ABSTRACT | A microfluidic system for causing perturbations in a cell membrane includes (a) a microfluidic channel defining a lumen and configured such that a cell suspended in a buffer can pass there through, and (b) source or emitter of an energy field. The microfluidic channel may include a cell-deforming constriction. A diameter of the constriction may be a function of the diameter of the cell. Related apparatus, systems, techniques, and articles are also described. |
| FILED | Friday, November 13, 2015 |
| APPL NO | 15/526517 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 35/02 (20130101) Original (OR) Class C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) C12N 15/87 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526578 | Woodruff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Teresa K. Woodruff (Chicago, Illinois); Ji-Yong Julie Kim (Elmhurst, Illinois); Joanna E. Burdette (Chicago, Illinois); Spiro Getsios (Chicago, Illinois); Sevim Yildiz Arslan (Chicago, Illinois); Shuo Xiao (Chicago, Illinois); Jie Zhu (Chicago, Illinois) |
| ABSTRACT | The present invention relates generally to a three-dimensional cell and tissue culture system for the female reproductive tract. In particular provided herein the system includes individual female reproductive cultures in a dynamic microfluidic setting or integrated using a microfluidic microphysiologic system. In some embodiments, the present invention provides ex-vivo female reproductive tract integration in a three dimensional (3D) microphysiologic system. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/639579 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0682 (20130101) Original (OR) Class C12N 2501/11 (20130101) C12N 2501/31 (20130101) C12N 2502/243 (20130101) C12N 2513/00 (20130101) C12N 2533/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526583 | Potter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Mark R. Potter (Gainesville, Florida); Barry John Byrne (Gainesville, Florida) |
| ABSTRACT | Provided herein are compositions and methods related to purification of recombinant adeno-associated virus (rAAV) particles. |
| FILED | Thursday, July 02, 2015 |
| APPL NO | 15/322809 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2750/14132 (20130101) C12N 2750/14143 (20130101) C12N 2750/14151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526589 | Tsai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Shengdar Tsai (Charlestown, Massachusetts); J. Keith Joung (Winchester, Massachusetts) |
| ABSTRACT | Methods and constructs for the multiplex expression of highly active CRISPR guide RNAs (gRNAs) from RNA Polymerase II and III promoters, optionally in mammalian cells. The present invention is based, at least in part, on the discovery that Csy4, an endoribonuclease that recognizes a short RNA hairpin sequence, can be used to cleave out multiple functional gRNAs encoded on a single longer RNA transcript (produced from an RNA pol II or III promoter) in which the individual gRNAs are separated by Csy4 cleavage sites. |
| FILED | Thursday, September 18, 2014 |
| APPL NO | 15/107550 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/4705 (20130101) C07K 2319/40 (20130101) C07K 2319/43 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/63 (20130101) C12N 15/1136 (20130101) C12N 2310/20 (20170501) C12N 2310/318 (20130101) C12N 2310/321 (20130101) C12N 2310/3231 (20130101) C12N 2310/3341 (20130101) C12N 2310/3521 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526591 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Benjamin Kleinstiver (Medford, Massachusetts); Vikram Pattanayak (Wellesley, Massachusetts) |
| ABSTRACT | Engineered CRISPR-Cas9 nucleases with improved specificity and their use in genomic engineering, epigenomic engineering, genome targeting, and genome editing. |
| FILED | Monday, March 26, 2018 |
| APPL NO | 15/935299 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/00 (20130101) C07K 2319/71 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/22 (20130101) Original (OR) Class C12N 15/90 (20130101) C12N 15/902 (20130101) C12N 15/907 (20130101) C12N 2800/22 (20130101) Enzymes C12Y 114/11 (20130101) C12Y 201/01043 (20130101) C12Y 203/01048 (20130101) C12Y 301/00 (20130101) C12Y 305/01098 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526604 | Bennett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California) |
| ASSIGNEE(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California) |
| INVENTOR(S) | C. Frank Bennett (Carlsbad, California); Huynh-Hoa Bui (San Diego, California); Kenneth W. Dobie (Solana Beach, California) |
| ABSTRACT | Provided herein are methods, compounds, and compositions for reducing expression of a nrRNA in an animal. Also provided herein are methods, compounds, and compositions for treating, ameliorating, delaying or reducing a symptom of a disease or disorder associated with a nuclear-retained RNA in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate a disease or condition associated with a nuclear-retained RNA, or a symptom thereof. |
| FILED | Thursday, July 06, 2017 |
| APPL NO | 15/642709 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/341 (20130101) C12N 2310/346 (20130101) C12N 2310/3181 (20130101) C12N 2310/3231 (20130101) C12N 2310/3341 (20130101) C12N 2310/3525 (20130101) C12N 2310/3525 (20130101) C12N 2310/3527 (20130101) C12N 2310/3533 (20130101) Enzymes C12Y 207/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526606 | Lou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Zhenkun Lou (Rochester, Minnesota); JungJin Kim (Rochester, Minnesota); SeungBaek Lee (Rochester, Minnesota) |
| ABSTRACT | Materials and methods for treating cancer (e.g., by reducing metastasis) are provided herein. For example, materials and methods for treating cancer by targeting WSB1 and/or pVHL are provided. |
| FILED | Friday, September 21, 2018 |
| APPL NO | 16/138695 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Peptides C07K 16/40 (20130101) C07K 2317/75 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) C12N 15/1135 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/531 (20130101) Enzymes C12Y 603/02019 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526616 | Kotha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Shiva Prasad Kotha (Mechanicville, New York); Andre Ronald Watson (Troy, New York); Vaibhav A. Pandit (Troy, New York) |
| ABSTRACT | An improved nanoparticle for transfecting cells is provided. The nanoparticle includes a core polyplex and a silica coating on the core polyplex and, optionally, a polymer attached to an outer surface of the silica coating, where the polyplex includes an anionic polymer, a cationic polymer, a cationic polypeptide, and a polynucleotide. Also provided is an improved method of modifying intracellular polynucleotides. The method includes contacting a cell with a nanoparticle that includes a core polyplex and a silica coating on the core polyplex and, optionally, a polymer attached to an outer surface of the silica coating, where the polyplex includes an anionic polymer, a cationic polymer, a cationic polypeptide, and a polynucleotide. |
| FILED | Tuesday, September 23, 2014 |
| APPL NO | 15/024264 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6455 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) A61K 48/0041 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 15/88 (20130101) C12N 2800/95 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526638 | Georgiou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AEMASE, INC. (Austin, Texas) |
| ASSIGNEE(S) | AEMase, Inc. (Austin, Texas) |
| INVENTOR(S) | George Georgiou (Austin, Texas); Everett Stone (Austin, Texas) |
| ABSTRACT | Methods and composition related to the engineering of a novel protein with methionine-γ-lyase enzyme activity are described. For example, in certain aspects there may be disclosed a modified cystathionine-γ-lyase (CGL) comprising one or more amino acid substitutions and capable of degrading methionine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with methionine depletion using the disclosed proteins or nucleic acids. |
| FILED | Friday, February 02, 2018 |
| APPL NO | 15/887276 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 9/96 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/10 (20130101) C12Q 1/527 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/988 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526647 | Kalachikov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sergey Kalachikov (New York, New York); Jingyue Ju (New York, New York); Irina Morozova (New York, New York); Michael Dorwart (Mountain View, California) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); ROCHE SEQUENCING SOLUTIONS, INC. (Pleasanton, California) |
| INVENTOR(S) | Sergey Kalachikov (New York, New York); Jingyue Ju (New York, New York); Irina Morozova (New York, New York); Michael Dorwart (Mountain View, California) |
| ABSTRACT | This disclosure provides chips, systems and methods for sequencing a nucleic acid sample. Tagged nucleotides are provided into a reaction chamber comprising a nanopore in a membrane. An individual tagged nucleotide of the tagged nucleotides can contain a tag coupled to a nucleotide, which tag is detectable with the aid of the nanopore. Next, an individual tagged nucleotide of the tagged nucleotides can be incorporated into a growing strand complementary to a single stranded nucleic acid molecule derived from the nucleic acid sample. With the aid of the nanopore, a tag associated with the individual tagged nucleotide can be detected upon incorporation of the individual tagged nucleotide. The tag can be detected with the aid of the nanopore when the tag is released from the nucleotide. |
| FILED | Friday, March 03, 2017 |
| APPL NO | 15/449757 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2527/113 (20130101) C12Q 2527/113 (20130101) C12Q 2535/122 (20130101) C12Q 2537/157 (20130101) C12Q 2563/113 (20130101) C12Q 2563/113 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44717 (20130101) G01N 27/44791 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526649 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Fei Chen (Cambridge, Massachusetts); Shahar Alon (Cambridge, Massachusetts); Andrew Payne (Cambridge, Massachusetts); Asmamaw Wassie (Boston, Massachusetts); Daniel Goodwin (Somerville, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Evan Daugharthy (Cambridge, Massachusetts); Jonathan Scheiman (New York, New York) |
| ABSTRACT | The invention provides in situ nucleic acid sequencing to be conducted in biological specimens that have been physically expanded. The invention leverages the techniques for expansion microscopy (ExM) to provide new methods for in situ sequencing of nucleic acids in a process referred to herein as “expansion sequencing” (ExSEQ). |
| FILED | Friday, October 20, 2017 |
| APPL NO | 15/789419 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) C12Q 1/6841 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2545/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526651 | Lindquist et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Susan L. Lindquist (Cambridge, Massachusetts); Aaron D. Gitler (Philadelphia, Pennsylvania); Anil Cashikar (Martinez, Georgia); Antony A. Cooper (Kansas City, Missouri); Cole M. Haynes (New York, New York) |
| ABSTRACT | Disclosed are compositions and methods for modulating expression of genes that function at the step of ER to Golgi trafficking. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. |
| FILED | Friday, January 18, 2013 |
| APPL NO | 13/745052 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) G01N 33/5023 (20130101) G01N 2500/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526662 | Kashani-Sabet et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sutter Bay Hospitals (San Francisco, California) |
| ASSIGNEE(S) | Sutter Bay Hospitals (San Francisco, California) |
| INVENTOR(S) | Mohammed Kashani-Sabet (San Francisco, California); Altaf A. Dar (San Bruno, California) |
| ABSTRACT | The disclosure provides methods for predicting and/or determining whether a subject has cancer based on the level of expression of BPTF. The disclosure also provides methods for determining whether a cancer in a subject is progressing or regressing based upon the change of expression levels of BPTF between two time points. The disclosure further provides methods to treat a subject with a cancer by administering a polynucleotide comprising an inhibitory BPTF nucleic acid and/or an agent that inhibits the expression or activity of BPTF. |
| FILED | Monday, March 19, 2018 |
| APPL NO | 15/925500 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5743 (20130101) G01N 33/6872 (20130101) G01N 33/57407 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526665 | Schorey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Jeffrey S. Schorey (Granger, Indiana); Prachi Pratap Singh (South Bend, Indiana); Yong Cheng (South Bend, Indiana) |
| ABSTRACT | The disclosure provides a method for diagnosing an active mycobacterium tuberculosis infection by detecting certain RNA biomarkers present in secreted extracellular vesicles isolated from a bodily fluid. The RNA biomarkers in the secreted extracellular vesicles may include a certain mycobacterium RNAs as well as certain host cell RNAs. Also provided is an RNA signature of certain mycobacterium and host cell RNA present in secreted extracellular vesicles indicative of an active tuberculosis infection. |
| FILED | Friday, March 03, 2017 |
| APPL NO | 15/449324 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527544 | Titus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Jitto Titus (Acworth, Georgia); Emilie Viennois (Atlanta, Georgia); A. G. Unil Perera (Mableton, Georgia); Merlin Didier (Decatur, Georgia) |
| ABSTRACT | Disclosed are methods, systems, and apparatuses for non-invasive detection of colitis in a subject. The methods involve depositing a bodily fluid sample from the subject on an internal reflection element (IRE). A beam of infrared (IR) radiation can then be directed through the IRE under conditions such that the IR radiation interacts with the bodily fluid sample. An absorption spectrum can then be recorded over a range of preselected frequencies to detect peaks that are affected by colitis. In preferred embodiments, the methods and systems involve Fourier Transform Infrared Spectroscopy (FTIR). |
| FILED | Monday, June 13, 2016 |
| APPL NO | 15/735661 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4255 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/552 (20130101) Original (OR) Class G01N 21/3581 (20130101) G01N 2021/3595 (20130101) G01N 2800/067 (20130101) G01N 2800/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527577 | Jothimuthu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); The United States of America as represented by the Department of Veteran Affairs (Washington DC) (Washington, District of Columbia) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The United States of America as represented by the Department of Veteran Affairs (Washington DC) (Washington, District of Columbia) |
| INVENTOR(S) | Preetha Jothimuthu (Santa Clara, California); Mohammed Inayathullah Nazir Ahmed (Santa Clara, California); Wen A. Tian (Redwood City, California); Jayakumar Rajadas (Cupertino, California); Mark Nicolls (Palo Alto, California); JooChuan Ang (Berkeley, California) |
| ABSTRACT | Improved electrochemical impedance spectroscopy assays are provided by electrodepositing metallic nanoparticles onto the working electrode for electrochemical impedance spectroscopy. The metallic nanoparticles provide improved assay sensitivity. Electrodeposition of the metallic nanoparticles firmly affixes them to the working electrode, thereby making it easier to clean the working electrode from one assay to the next assay without undesirably removing the metallic nanoparticles. |
| FILED | Tuesday, July 18, 2017 |
| APPL NO | 15/653336 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/31 (20130101) C23C 18/1824 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 5/02 (20130101) C25D 13/02 (20130101) C25D 13/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3278 (20130101) Original (OR) Class G01N 27/4145 (20130101) G01N 27/4146 (20130101) G01N 33/53 (20130101) G01N 33/5438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527579 | Bashir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Rashid Bashir (Champaign, Illinois); Vikhram Vilasur Swaminathan (Urbana, Illinois); Bobby Reddy, Jr. (Savoy, Illinois); Eric M. Salm (Champaign, Illinois); Carlos Duarte-Guevara (Urbana, Illinois) |
| ABSTRACT | Provided are methods and devices for the label free detection of analytes in solution, including analytes suspended in a biological fluid. A field effect transistor (FET) is positioned in close proximity to a paired set of reference electrodes and the reference electrodes electrically biased to provide desalting and a stable gate voltage to the FET. In this manner, charged ions are depleted in the sensing region of the sensor and device sensitivity to analyte detection improved by the removal of charge that otherwise interferes with measurement. Also provided are methods and systems providing increased in reference electrode surface area and/or decrease in droplet volume to further improve label-free detection of analytes. |
| FILED | Friday, March 27, 2015 |
| APPL NO | 15/128879 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) Original (OR) Class G01N 27/4146 (20130101) G01N 33/5438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527626 | Chiu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Daniel T. Chiu (Seattle, Washington); Mengxia Zhao (Seattle, Washington); Wyatt Nelson (Seattle, Washington); Perry G. Schiro (Seattle, Washington) |
| ABSTRACT | Provided herein, among other aspects, are methods and apparatuses for analyzing particles in a sample. In some aspects, the particles can be analytes, cells, nucleic acids, or proteins and contacted with a tag, partitioned into aliquots, detected by a ranking device, and isolated. The methods and apparatuses provided herein may include a microfluidic chip. In some aspects, the methods and apparatuses may be used to quantify rare particles in a sample, such as cancer cells and other rare cells for disease diagnosis, prognosis, or treatment. |
| FILED | Tuesday, July 01, 2014 |
| APPL NO | 14/903012 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/561 (20130101) B01L 3/567 (20130101) B01L 3/502761 (20130101) B01L 2200/10 (20130101) B01L 2300/0636 (20130101) B01L 2300/0681 (20130101) B01L 2300/0832 (20130101) B01L 2400/06 (20130101) B01L 2400/086 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5304 (20130101) G01N 33/57492 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527631 | Antebi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Yaron E. Antebi (Pasadena, California); James Linton (Pasadena, California); Michael Elowitz (Los Angeles, California); Heidi Klumpe (Pasadena, California) |
| ABSTRACT | Methods and compositions are provided for the selective activation of a BMP-dependent response in certain cell types. Methods include identifying a ligand or ligand combinations as well as cell receptor profiles that result in selectively activating a ligand-dependent response through interactions with ligand receptors on a first cell type that do not activate the ligand-dependent response in a second cell type. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/847909 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2227/105 (20130101) Peptides C07K 14/71 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 33/6872 (20130101) Original (OR) Class G01N 33/56966 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527698 | Griswold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Mark A. Griswold (Shaker Heights, Ohio); Yun Jiang (Cleveland Heights, Ohio); Dan Ma (Cleveland, Ohio); Anagha Deshmane (Cleveland Heights, Ohio); Chaitra Badve (Cleveland Heights, Ohio); Vikas Gulani (Shaker Heights, Ohio); Jeffrey L. Sunshine (Pepper Pike, Ohio) |
| ABSTRACT | Apparatus, methods, and other embodiments associated with NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals, and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals. The NMR signal evolution may be assigned to a cluster based on the characterization of the resonant species. Cluster overlay maps may be produced simultaneously based, at least in part, on the clustering. The clusters may be associated with different tissue types. |
| FILED | Friday, August 03, 2018 |
| APPL NO | 16/053873 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/4828 (20130101) G01R 33/5608 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527699 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Redwood City, California) |
| INVENTOR(S) | Joseph Y. Cheng (Los Altos, California); Shreyas S. Vasanawala (Stanford, California) |
| ABSTRACT | An MRI apparatus performs multi-channel calibration acquisitions using a multi-channel receiver array and uses a convolutional neural network (CNN) to compute an estimated profile map that characterizes properties of the multi-channel receiver array. The profile map is composed of orthogonal vectors and transforms single-channel image space data to multi-channel image space data. The MRI apparatus performs a prospectively subsampled imaging acquisition and processes the resulting k-space data using the estimated profile map to reconstruct a final image. The CNN may be pretrained in an unsupervised manner using subsampled simulated multi-channel calibration acquisitions and using a regularization function included in a training loss function. |
| FILED | Wednesday, August 01, 2018 |
| APPL NO | 16/052527 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/5612 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/088 (20130101) G06N 5/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527700 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Curtis L. Johnson (Wilmington, Delaware); Bradley P. Sutton (Savoy, Illinois); Joseph L. Holtrop (Memphis, Tennessee) |
| ABSTRACT | A method and system provides an acquisition scheme for generating magnetic resonance elastography displacement data with whole-sample coverage, high spatial resolution, and adequate SNR in a short scan time. The method and system can acquire in-plane and through-plane k-space shots over a volume of a sample divided into a plurality of slabs that each include a plurality of non-adjacent slices to obtain three dimensional multiband, multishot data, can apply multiband radio frequency refocusing pulses to the sample, can acquire navigators before readout, and can correct for non-linear motion errors. |
| FILED | Wednesday, October 18, 2017 |
| APPL NO | 15/787462 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4826 (20130101) G01R 33/4835 (20130101) G01R 33/5611 (20130101) G01R 33/5673 (20130101) Original (OR) Class G01R 33/5676 (20130101) G01R 33/56358 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528848 | Madabhushi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Jeffrey John Nirschl (Philadelphia, Pennsylvania); Andrew Janowczyk (East Meadow, New York); Eliot G. Peyster (Philadelphia, Pennsylvania); Michael D. Feldman (Wilmington, Delaware); Kenneth B. Margulies (Villanova, Pennsylvania) |
| ABSTRACT | Methods, apparatus, and other embodiments predict heart failure from WSIs of cardiac histopathology using a deep learning convolutional neural network (CNN). One example apparatus includes a pre-processing circuit configured to generate a pre-processed WSI by downsampling a digital WSI; an image acquisition circuit configured to randomly select a set of non-overlapping ROIs from the pre-processed WSI, and configured to provide the set of non-overlapping ROIs to a deep learning circuit; a deep learning circuit configured to generate an image-level probability that a member of the set of non-overlapping ROIs is a failure/abnormal pathology ROI using a CNN; and a classification circuit configured to generate a patient-level probability that the patient from which the region of tissue represented in the WSI was acquired is experiencing failure or non-failure based, at least in part, on the image-level probability. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 15/799129 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/2054 (20130101) G06K 9/6256 (20130101) Original (OR) Class G06K 9/6277 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0472 (20130101) Image Data Processing or Generation, in General G06T 3/40 (20130101) G06T 2207/10024 (20130101) G06T 2207/20076 (20130101) G06T 2207/30048 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529061 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ruikang K. Wang (Seattle, Washington); Anqi Zhang (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Ruikang K. Wang (Seattle, Washington); Anqi Zhang (Seattle, Washington) |
| ABSTRACT | Systems and methods of producing medical images of a subject are disclosed herein. In one embodiment, structural data and vascular data are acquired from a region of interest in the subject. A filter is generated using structural image data acquired from a second layer and blood flow image data received from a first layer in the region of interest. The filter is applied to vascular image data acquired from a second, deeper layer in the region of interest to form an image of the second layer having reduced tailing artifacts relative to the unfiltered vascular image data. |
| FILED | Friday, August 12, 2016 |
| APPL NO | 15/751443 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) A61B 3/0025 (20130101) A61B 3/102 (20130101) A61B 3/1233 (20130101) Image Data Processing or Generation, in General G06T 5/004 (20130101) Original (OR) Class G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 7/187 (20170101) G06T 2207/10028 (20130101) G06T 2207/10101 (20130101) G06T 2207/30041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529127 | Black et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Michael J. Black (Tuebingen, Germany); Peng Guan (Mountain View, California) |
| ABSTRACT | A system generates a clothing deformation model which models one or more of a pose-dependent clothing shape variation which is induced by underlying body pose parameters, a pose-independent clothing shape variation which is induced by clothing size and underlying body shape parameters and a clothing shape variation including a combination of the pose-dependent clothing shape variation and/or the pose-independent clothing shape variation. The system generates, for an input human body, a custom-shaped garment associated with a clothing type by mapping, via the clothing deformation model, body shape parameters of the input human body to clothing shape parameters of the clothing type and dresses the input human body with the custom-shaped garment. |
| FILED | Wednesday, July 03, 2019 |
| APPL NO | 16/502718 |
| ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 17/5009 (20130101) G06F 2217/32 (20130101) Image Data Processing or Generation, in General G06T 17/00 (20130101) Original (OR) Class G06T 19/20 (20130101) G06T 2210/16 (20130101) G06T 2219/2016 (20130101) G06T 2219/2021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10524663 | Boppart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Stephen A. Boppart (Champaign, Illinois); Paul Scott Carney (Champaign, Illinois); Nathan Shemonski (Urbana, Illinois) |
| ABSTRACT | Methods and apparatus for assessing and correcting phase variations and motion artifacts in a coherent tomogram of a sample. Coherent techniques are used scan a broadband optical beam across a sample in a specified scan pattern and to acquire a cube of complex data constituting a full tomogram. Generalized motion of the sample is then quantified based at least on a phase variation measured during the course of scanning the broadband optical beam in the specified scan pattern. Generalized motion includes both actual motion and apparent motion due to organized variation of some physical parameter such as temperature. Intensity structure of speckle imaged during the course of coherently acquiring the full tomograpm may be used to correct for motion of the sample in a plane transverse to a depth axis along the incident beam. |
| FILED | Friday, June 17, 2016 |
| APPL NO | 15/185410 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) Original (OR) Class A61B 5/7207 (20130101) A61B 2576/00 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02077 (20130101) G01B 9/02091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524664 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); OPTICENT, INC. (Deerfield, Illinois) |
| INVENTOR(S) | Wenzhong Liu (Evanston, Illinois); Lian Duan (Evanston, Illinois); Hao F. Zhang (Deerfield, Illinois); Kieren J. Patel (Santa Monica, California); Hao Li (Evanston, Illinois); Biqin Dong (Evanston, Illinois); Amani A. Fawzi (Chicago, Illinois) |
| ABSTRACT | The present disclosure provides systems and methods for the determining a rate of change of one or more analyte concentrations in a target using non invasive non contact imaging techniques such as OCT. Generally, OCT data is acquired and optical information is extracted from OCT scans to quantitatively determine a flow rate of fluid in the target; angiography is also performed using one or more fast scanning methods to determine a concentration of one or more analytes. Both calculations can provide a means to determine a change in rate of an analyte over time. Example methods and systems of the disclosure may be used in assessing metabolism of a tissue, where oxygen is the analyte detected, or other functional states, and be generally used for the diagnosis, monitoring and treatment of disease. |
| FILED | Monday, May 01, 2017 |
| APPL NO | 15/583615 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/0066 (20130101) Original (OR) Class A61B 5/145 (20130101) A61B 5/489 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10016 (20130101) G06T 2207/10101 (20130101) G06T 2207/30104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524699 | Sullivan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Christopher Sullivan (Rochester, New York); Elizabeth DeBartolo (Pittsford, New York); Kathleen Lamkin-Kennard (Hamlin, New York) |
| ASSIGNEE(S) | ROCHESTER INSTITUTE OF TECHNOLOGY (Rochester, New York) |
| INVENTOR(S) | Christopher Sullivan (Rochester, New York); Elizabeth DeBartolo (Pittsford, New York); Kathleen Lamkin-Kennard (Hamlin, New York) |
| ABSTRACT | The system and method of the present invention utilizes one or more sensors to generate data attached to a person interfaced with a data monitoring computing device and a data management computing device monitoring the terrain the individual is traversing and gait at which the individual is traversing the terrain, in addition to predicting the terrain the individual is about to traverse. |
| FILED | Friday, December 20, 2013 |
| APPL NO | 14/136567 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0002 (20130101) A61B 5/112 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524950 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Shang-Li Wu (Albany, California); Homayoon Kazerooni (Berkeley, California) |
| ABSTRACT | Systems, methods, and apparatus provide an artificial knee. Such artificial knees may include a thigh link configured to move in unison with a thigh of the person, a shank link configured to be rotatably coupled to the thigh link, and a compression spring rotatably coupled to the thigh link at a first end and coupled to the shank link at a second end. The compression spring is configured to provide an extension torque between the thigh link and the shank link during a first range of motion of the thigh link and the shank link relative to each other. The compression spring is configured to provide a flexion torque between the thigh link and the shank link during a second range of motion of the thigh link and the shank link relative to each other. |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/898102 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/68 (20130101) A61F 2/644 (20130101) A61F 5/0123 (20130101) A61F 5/0125 (20130101) Original (OR) Class A61F 2002/503 (20130101) A61F 2002/5018 (20130101) A61F 2002/5033 (20130101) A61F 2002/5075 (20130101) A61F 2002/5079 (20130101) A61F 2005/0141 (20130101) A61F 2005/0144 (20130101) A61F 2005/0158 (20130101) A61F 2005/0169 (20130101) A61F 2005/0179 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10524974 | Tung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); U.S. Bionics, Inc. (Emeryville, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); U.S. Bionics, Inc. (Emeryville, California) |
| INVENTOR(S) | Wayne Yi-Wei Tung (Berkeley, California); Nathan Poon (Oakland, California); Theerapat Yangyuenthanasan (Berkeley, California); Homayoon Kazerooni (Berkeley, California) |
| ABSTRACT | A trunk supporting exoskeleton comprises: a supporting trunk; thigh links configured to move in unison with a wearer's thighs; and first and second torque generators located on both left and right halves of the wearer substantially close to the wearer's hip. The torque generators couple the supporting trunk to the thigh links, and generate torque between the thigh links and the supporting trunk. When the wearer bends forward such that a predetermined portion of the supporting trunk passes beyond a predetermined angle from vertical, a torque generator(s) imposes a resisting torque between the supporting trunk and the thigh link(s), causing the supporting trunk to impose a force against the wearer's trunk, and the thigh link(s) to impose a force onto the wearer's thigh. When the predetermined portion does not pass beyond the predetermined angle, the torque generators impose no resisting torques between said supporting trunk and respective thigh links. |
| FILED | Wednesday, January 09, 2019 |
| APPL NO | 16/243942 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/00 (20130101) A61H 1/0244 (20130101) A61H 1/0292 (20130101) A61H 3/00 (20130101) Original (OR) Class A61H 2003/007 (20130101) A61H 2201/018 (20130101) A61H 2201/1621 (20130101) A61H 2201/1642 (20130101) A61H 2201/1652 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525081 | Ray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Grove City College (Grove City, Pennsylvania) |
| ASSIGNEE(S) | Grove City College (Grove City, Pennsylvania) |
| INVENTOR(S) | Durwood B. Ray (Grove City, Pennsylvania); David Jones (Grove City, Pennsylvania) |
| ABSTRACT | Provided herein, inter alia, are tumorigenic cell lines and methods for using the same for deriving a series of cell culture and non-human animal-based models which exhibit increasingly aggressive tumorigenic potential as well as use of the same for evaluating the anti-neoplastic properties of candidate therapeutic agents. |
| FILED | Monday, July 31, 2017 |
| APPL NO | 15/664305 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 2227/105 (20130101) A01K 2267/0331 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/13 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525407 | Wachsman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Eric D. Wachsman (Fulton, Maryland); Dongxia Liu (College Park, Maryland) |
| ABSTRACT | Non-oxidative direct methane conversion (NDMC) to value-added products, such as H2, C2 hydrocarbons, and aromatics, occurs within a reactor heated to an elevated temperature. The reactor can have a first volume, where a feed gas including methane is provided, separated from a second volume, where a sweep gas is provided, by a dense thin film membrane supported on a porous wall. The thin film membrane is a mixed ionic-electronic permeable membrane that allows H2 generated in the first volume to be transported to the second volume for removal by (or reaction with) the sweep gas. A catalyst can be provided in or adjacent to the first volume. For example, the catalyst can be a metal doped quartz material (e.g., Fe(c)SiO2) or a metal/zeolite material (e.g., Mo/ZSM5). Methane conversion and/or product selectivity in the reactor can be manipulated by control of gas flow rates, reaction temperatures, and/or feed and sweep gas compositions. |
| FILED | Thursday, October 06, 2016 |
| APPL NO | 15/765820 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/32 (20130101) Original (OR) Class B01D 71/024 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/065 (20130101) B01J 8/0221 (20130101) B01J 8/0278 (20130101) B01J 19/2475 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 25/006 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/6265 (20130101) C04B 2111/00801 (20130101) C04B 2235/449 (20130101) C04B 2235/3213 (20130101) C04B 2235/3217 (20130101) Acyclic or Carbocyclic Compounds C07C 2/84 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525424 | Alexiou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Ayse Asatekin Alexiou (Arlington, Massachusetts); Papatya Kaner (Cambridge, Massachusetts); Chiara Vannucci (Medford, Massachusetts) |
| ABSTRACT | A graft copolymer including zwitterionic repeat units and hydrophobic repeat units, in which the zwitterionic repeat units constitute 2-60 wt % of the graft copolymer and each of the hydrophobic repeat units is characterized in that a homopolymer formed thereof is miscible with polyvinylidene fluoride, polysulfone, poly ether sulfone, polyvinyl chloride, or polyacrylonitrile, each of the hydrophobic repeat units not being a repeat unit of polyvinylidene fluoride. Also disclosed is a filtration membrane containing such a graft copolymer or a statistical copolymer that includes the same composition of repeat units as the graft copolymer. Further disclosed are methods of preparing the graft copolymer and the filtration membrane. |
| FILED | Wednesday, December 30, 2015 |
| APPL NO | 15/541260 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Separation B01D 71/34 (20130101) B01D 71/40 (20130101) B01D 71/76 (20130101) B01D 71/78 (20130101) Original (OR) Class B01D 71/82 (20130101) B01D 2325/18 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 265/06 (20130101) C08F 297/02 (20130101) Compositions of Macromolecular Compounds C08L 51/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525457 | Bae et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Chulsung Bae (Cohoes, New York); Angela Dee Mohanty (Clifton Park, New York) |
| ABSTRACT | Embodiments of the invention relate generally to anion exchange membranes and, more particularly, to anion exchange membranes comprising a styrene block copolymer and methods for their manufacture. In one embodiment, the invention provides a polymer according to formula IV, wherein x and y are mol %, QA is or each of R1 and R2 is, independently, a linear alkyl chain or a cyclic alkyl chain, and Z is selected from a group consisting of: a linear alkyl chain, a cyclic alkyl chain, and an alkylene ether chain. |
| FILED | Wednesday, March 13, 2019 |
| APPL NO | 16/351989 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/14 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/04 (20130101) C08F 8/24 (20130101) C08F 8/42 (20130101) C08F 8/44 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 13/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/083 (20130101) H01M 8/103 (20130101) H01M 8/1023 (20130101) H01M 2008/1095 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/56 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525472 | Pandey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Santosh Pandey (Ames, Iowa); Riley Brien (Ann Arbor, Michigan); Taejoon Kong (Ames, Iowa); Zach Njus (Ames, Iowa); Jared Anderson (Cedar Rapids, Iowa) |
| ABSTRACT | Apparatus, methods, and systems for automated liquid droplet manipulation include an open droplet supporting surface. An actuator can translate the surface in space with at least one degree freedom of movement to influence movement of one or more droplets on the surface. In one embodiment, the surface is patterned with areas that attract the droplets and interstitial areas that repel the droplets to enhance transport of droplets. For example, for water-based droplets the attracting areas can be hydrophilic and the repelling hydrophobic. In one embodiment, the repelling areas are superhydrophobic. Electromechanical movement of the surface avoids expensive and complex microfluidic fabrication and components, and avoids electrowetting requirements. |
| FILED | Wednesday, April 27, 2016 |
| APPL NO | 15/140182 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502792 (20130101) Original (OR) Class B01L 2200/14 (20130101) B01L 2200/0605 (20130101) B01L 2300/123 (20130101) B01L 2300/126 (20130101) B01L 2300/165 (20130101) B01L 2300/166 (20130101) B01L 2400/0457 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525502 | Claridge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Shelley A Claridge (Lafayette, Indiana); Shi Wah Choong (West Lafayette, Indiana); Jae Jin Bang (West Lafayette, Indiana); Shane Richard Russell (West Lafayette, Indiana) |
| ABSTRACT | This invention discloses a method for controlling nanoscopic wetting near or at a molecular scale for synthetic material applications. In particular this invention relates to a method for preparing a monolayer or thin film with a patterned nanoscopic wetting surface using a ‘sitting’ phase of polymerizable amphiphile, wherein hydrophobic alkyl chains of the amphiphile extend along the supporting surface and the amphiphile molecules align side-to-side, effectively forming a repeating cross-section of bilayer with alternating hydrophilic and hydrophobic stripes of a ˜6 nm pitch tunable based on the chain length of the amphiphile. Products prepared according to the methods disclosed herein are within the scope of this invention. In some embodiments, monolayers or thin films so prepared are transferable. |
| FILED | Friday, January 19, 2018 |
| APPL NO | 15/875025 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/04 (20130101) B05D 1/18 (20130101) B05D 1/204 (20130101) B05D 5/04 (20130101) Original (OR) Class B05D 5/06 (20130101) B05D 5/08 (20130101) B05D 7/24 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 2217/75 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 139/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525632 | Penny et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ryan Wade Penny (Cambridge, Massachusetts); Anastasios John Hart (Waban, Massachusetts) |
| ABSTRACT | Methods, systems, and devices for precision locating additively manufactured components for assembly and/or post processing manufacturing are provided for herein. In some embodiments, at least one component can be additively manufactured to include one or more kinematic features on one or more surfaces of the component. The kinematic feature(s) can be configured to engage complementary kinematic feature(s) formed in a second component so the two components can form an assembly. Alternatively, the kinematic feature(s) can be configured to engage complementary kinematic feature(s) associated with a post-processing machine such that the one or more post-processing actions can be performed on the component after the component is precisely located with respect to the machine by way of the kinematic features of the component and associated with the machine. A variety of systems and methods that utilize kinematic features are also provided. |
| FILED | Wednesday, June 28, 2017 |
| APPL NO | 15/636502 |
| ART UNIT | 2118 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/24 (20130101) B22F 3/24 (20130101) B22F 3/1055 (20130101) B22F 5/00 (20130101) B22F 2003/1057 (20130101) B22F 2003/1058 (20130101) B22F 2005/005 (20130101) B22F 2005/005 (20130101) B22F 2207/20 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/40 (20170801) Original (OR) Class B29C 64/386 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/00 (20141201) B33Y 50/02 (20141201) B33Y 80/00 (20141201) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) G05B 2219/35134 (20130101) G05B 2219/49007 (20130101) G05B 2219/49023 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) Y02P 80/40 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526273 | Polavarapu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Prasad L. Polavarapu (Brentwood, Tennessee); Vijay Raghavan (Nashville, Tennessee) |
| ABSTRACT | Disclosed herein are surfactant compounds, that are surface active, liquid, chiral, and micelle forming. Also disclose herein are ionic liquids and compsitions comprising the surfactant compounds. |
| FILED | Thursday, January 24, 2019 |
| APPL NO | 16/256013 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 69/34 (20130101) Original (OR) Class C07C 69/67 (20130101) C07C 211/27 (20130101) C07C 211/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10526299 — Fiber conduit reactor with a heat exchange medium inlet and a heat exchange medium outlet
| US 10526299 | Massingill |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chemtor, LP (San Marcos, Texas) |
| ASSIGNEE(S) | Chemtor, LP (San Marcos, Texas) |
| INVENTOR(S) | John Lee Massingill (San Marcos, Texas) |
| ABSTRACT | An apparatus includes a conduit with two process fluid inlets at one end of the conduit, one process fluid outlet at an opposing end, a heat exchange medium inlet, and a heat exchange medium outlet. One of the fluid inlets includes a tube extending into the conduit and a perforated node at the end of the tube, and the other of the fluid inlets is arranged up stream of the perforated node. The apparatus further includes hollow tubes positioned longitudinally within the conduit between the two process fluid inlets, the process fluid outlet, the heat exchange medium inlet and the heat exchange medium outlet. In addition, the apparatus includes a collection vessel positioned proximate the fluid outlet and fibers extending through each of the hollow tubes, wherein one end of the fibers is secured to the perforated node and the other end of the fibers extends into the collection vessel. |
| FILED | Monday, August 05, 2019 |
| APPL NO | 16/532199 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 11/0449 (20130101) B01D 11/0453 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 14/00 (20130101) B01J 19/2415 (20130101) B01J 19/2475 (20130101) B01J 19/2495 (20130101) B01J 2219/24 (20130101) B01J 2219/00085 (20130101) B01J 2219/00599 (20130101) B01J 2219/3322 (20130101) Acyclic or Carbocyclic Compounds C07C 41/14 (20130101) C07C 41/16 (20130101) C07C 67/03 (20130101) Heterocyclic Compounds C07D 301/28 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/022 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/026 (20130101) C10L 2200/0476 (20130101) C10L 2270/026 (20130101) Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom C11C 3/04 (20130101) C11C 3/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526334 | Stoltz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Brian M. Stoltz (San Marino, California); Eric R. Welin (Pasadena, California); Scott C. Virgil (Pasadena, California); Pamela Tadross (Natick, Massachusetts); Gerit Maria Pototschnig (San Diego, California); Aurapat (Fa) Ngamnithiporn (Pasadena, California); Kenji Negoro (Ibaraki, Japan); Guillaume Lapointe (San Francisco, California); Max Klatte (Loerrach, Germany); Christopher Haley (Boston, Massachusetts); Christian Gruenanger (Mannheim, Germany); Emil Glibstrup (Copenhagen, Denmark); Christopher Gilmore (Natick, Massachusetts); Kevin McCormack Allan (Belmont, California) |
| ABSTRACT | (−)-Jorumycin, ecteinascidin 743, saframycin A and related compounds, methods of preparing the same, formulations comprising the compounds, and methods of treating proliferative diseases with the same are provided. |
| FILED | Wednesday, July 18, 2018 |
| APPL NO | 16/038968 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 471/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526611 | Gelvin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Stanton B Gelvin (West Lafayette, Indiana); Lan-Ying Lee (West Lafayette, Indiana); Yaling Wang (Shanghai, China PRC) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Stanton B Gelvin (West Lafayette, Indiana); Lan-Ying Lee (West Lafayette, Indiana); Yaling Wang (Shanghai, China PRC) |
| ABSTRACT | The present invention provides methods and compositions for enhancing the efficiency of Agrobacterium-mediated transformation of host cells, such as plant cells, wherein the host cells overexpress light-dependent short hypocotyls 10 (LSH10) protein. The methods of the invention comprise Agrobacterium-mediated transfer of T-DNA to a plant cell, wherein the T-DNA contains a DNA of interest to be inserted into a plant genome at a homologous position. |
| FILED | Friday, April 03, 2015 |
| APPL NO | 15/301533 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/8205 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526614 | Gregory et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Brian Gregory (Swedesboro, New Jersey); Shawn Foley (Ambler, Pennsylvania) |
| ABSTRACT | Compositions and methods for modulating root hair production and stress responses in plants are provided. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/846699 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8223 (20130101) C12N 15/8237 (20130101) C12N 15/8261 (20130101) C12N 15/8271 (20130101) Original (OR) Class C12N 2840/002 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526624 | Angenent et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Largus T. Angenent (Tübingen, Germany); Leo Kucek (Waukesha, Wisconsin) |
| ABSTRACT | Methods and systems to produce product compositions comprising caprylate products using chain-elongating bacteria. For example, the caprylate product in the product composition is n-caprylic acid (C8) and the n-caprylic (C8) to n-caproic (C6) acid ratio is higher than 1:1. These methods use chain elongation towards C8 rather than C6. High n-caprylate productivity and specificity was accomplished by: 1) feeding a substrate with, for example, ethanol as the carbon source or alternatively, a high ethanol-to-acetate ratio as the carbon source; 2) extracting caprylate product(s) (e.g., n-caprylate product) from the bioreactor broth; and 3) acclimating an efficient chain-elongating microbiome. The methods can produce caprylate products such as, for example, n-caprylic acid, which is a higher value chemical than C4 and C6. |
| FILED | Friday, May 26, 2017 |
| APPL NO | 15/607188 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526633 | Ramasamy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| INVENTOR(S) | Ramaraja P. Ramasamy (Watkinsville, Georgia); Yi Fang (Athens, Georgia) |
| ABSTRACT | Provided herein are plant/plant pathogen volatile compound electrochemical sensors, plant/plant pathogen volatile detection systems, and methods for detecting stress-induced plant volatile compounds and/or a plant-pathogen emitted volatile compounds. |
| FILED | Friday, April 15, 2016 |
| APPL NO | 15/566438 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/005 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3277 (20130101) G01N 27/3278 (20130101) G01N 33/025 (20130101) G01N 33/0047 (20130101) G01N 33/0098 (20130101) G01N 33/483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526723 | Doolittle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | William Alan Doolittle (Atlanta, Georgia); Evan A. Clinton (Atlanta, Georgia); Chloe A. M. Fabien (Atlanta, Georgia); Brendan Patrick Gunning (Atlanta, Georgia); Joseph J. Merola (Atlanta, Georgia) |
| ABSTRACT | Systems and methods are disclosed for rapid growth of Group III metal nitrides using plasma assisted molecular beam epitaxy. The disclosure includes higher pressure and flow rates of nitrogen in the plasma, and the application of mixtures of nitrogen and an inert gas. Growth rates exceeding 8 μm/hour can be achieved. |
| FILED | Thursday, June 16, 2016 |
| APPL NO | 15/738458 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/221 (20130101) C23C 14/0641 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/025 (20130101) Original (OR) Class C30B 29/406 (20130101) C30B 31/06 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0242 (20130101) H01L 21/0254 (20130101) H01L 21/02576 (20130101) H01L 21/02631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527507 | Wood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert J. Wood (Cambridge, Massachusetts); Yong-Lae Park (Cambridge, Massachusetts); Carmel S. Majidi (Pittsburgh, Pennsylvania); Bor-rong Chen (Medford, Massachusetts); Leia Stirling (Stoneham, Massachusetts); Conor James Walsh (Dublin, Ireland); Radhika Nagpal (Cambridge, Massachusetts); Diana Young (Boston, Massachusetts); Yigit Menguc (Somerville, Massachusetts) |
| ABSTRACT | An elastic strain sensor can be incorporated into an artificial skin that can sense flexing by the underlying support structure of the skin to detect and track motion of the support structure. The unidirectional elastic strain sensor can be formed by filling two or more channels in an elastic substrate material with a conductive liquid. At the ends of the channels, a loop port connects the channels to form a serpentine channel. The channels extend along the direction of strain and the loop portions have sufficiently large cross-sectional area in the direction transverse to the direction of strain that the sensor is unidirectional. The resistance is measured at the ends of the serpentine channel and can be used to determine the strain on the sensor. Additional channels can be added to increase the sensitivity of the sensor. The sensors can be stacked on top of each other to increase the sensitivity of the sensor. In other embodiments, two sensors oriented in different directions can be stacked on top of each other and bonded together to form a bidirectional sensor. A third sensor formed by in the shape of a spiral or concentric rings can be stacked on top and used to sense contact or pressure, forming a three dimensional sensor. The three dimensional sensor can be incorporated into an artificial skin to provide advanced sensing. |
| FILED | Monday, November 27, 2017 |
| APPL NO | 15/823030 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Characteristic Features of Footwear; Parts of Footwear A43B 13/203 (20130101) A43B 23/029 (20130101) Diagnosis; Surgery; Identification A61B 5/112 (20130101) A61B 5/1036 (20130101) A61B 5/6807 (20130101) A61B 2562/0247 (20130101) A61B 2562/0261 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/105 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 13/08 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/22 (20130101) Original (OR) Class G01L 1/2287 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527579 | Bashir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Rashid Bashir (Champaign, Illinois); Vikhram Vilasur Swaminathan (Urbana, Illinois); Bobby Reddy, Jr. (Savoy, Illinois); Eric M. Salm (Champaign, Illinois); Carlos Duarte-Guevara (Urbana, Illinois) |
| ABSTRACT | Provided are methods and devices for the label free detection of analytes in solution, including analytes suspended in a biological fluid. A field effect transistor (FET) is positioned in close proximity to a paired set of reference electrodes and the reference electrodes electrically biased to provide desalting and a stable gate voltage to the FET. In this manner, charged ions are depleted in the sensing region of the sensor and device sensitivity to analyte detection improved by the removal of charge that otherwise interferes with measurement. Also provided are methods and systems providing increased in reference electrode surface area and/or decrease in droplet volume to further improve label-free detection of analytes. |
| FILED | Friday, March 27, 2015 |
| APPL NO | 15/128879 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) Original (OR) Class G01N 27/4146 (20130101) G01N 33/5438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527631 | Antebi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Yaron E. Antebi (Pasadena, California); James Linton (Pasadena, California); Michael Elowitz (Los Angeles, California); Heidi Klumpe (Pasadena, California) |
| ABSTRACT | Methods and compositions are provided for the selective activation of a BMP-dependent response in certain cell types. Methods include identifying a ligand or ligand combinations as well as cell receptor profiles that result in selectively activating a ligand-dependent response through interactions with ligand receptors on a first cell type that do not activate the ligand-dependent response in a second cell type. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/847909 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2227/105 (20130101) Peptides C07K 14/71 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 33/6872 (20130101) Original (OR) Class G01N 33/56966 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527712 | Lam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Emily W. Lam (Cambridge, Massachusetts); Thomas D. C. Little (Newton, Massachusetts) |
| ABSTRACT | A positioning system includes a steerable laser configured to emit a laser beam, an optical receiver, one or more processors, and a memory device. The optical receiver is configured to detect the presence of the laser beam on the optical receiver, measure a received signal strength of light emitted by a luminaire, or both. The memory device stores instructions that, when executed by at least one of the one or more processors cause the positioning system to target the laser beam on the optical receiver, and based on a first angle of the laser beam, a second angle of the laser beam, and an isointense curve associated with the optical receiver and the luminaire, estimate three-dimensional position of the optical receiver relative to the steerable laser source. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 16/414149 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/002 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527783 | Badding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | John V. Badding (State College, Pennsylvania); Justin R. Sparks (Coopersburg, Pennsylvania) |
| ABSTRACT | The invention relates to Cr2+:ZnSe core optical fibers and methods of fabricating thereof, including a hybrid physical-chemical vapor deposition reaction. The invention relates also to Cr2+:ZnSe optical fiber lasers, in particular to a crystalline semiconductor optical fiber laser. |
| FILED | Thursday, August 17, 2017 |
| APPL NO | 15/679351 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/32 (20130101) C03C 3/321 (20130101) C03C 13/043 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02395 (20130101) Original (OR) Class G02B 13/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528687 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Regents of the University of Minnesota (Minneapolis, Minnesota); ETH Zürich (Zürich, Switzerland) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); ETH Zürich (Zürich, Switzerland) |
| INVENTOR(S) | Brian Benjamin Johnson (Denver, Colorado); Nathan Ainsworth (Brown Deer, Wisconsin); Sairaj Vijaykumar Dhople (Minneapolis, Minnesota); Mohit Sinha (St. Paul, Minnesota); Florian Anton Dörfler (Zürich, Switzerland) |
| ABSTRACT | Virtual oscillator control systems, devices, and techniques are provided. One example device includes a processor configured to implement a virtual oscillator circuit and output an oscillating waveform based on the virtual oscillator circuit and power electronics operatively coupled to the processor and configured to convert, based on the oscillating waveform, direct current (DC) electricity to alternating current (AC) electricity. The processor may be further configured to extract, from the virtual oscillator circuit, a virtual current based on an output current of the AC electricity, and output the oscillating waveform further based on an input voltage of the DC electricity. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 15/581824 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/2513 (20130101) G01R 21/133 (20130101) G01R 31/42 (20130101) G01R 35/04 (20130101) Electric Digital Data Processing G06F 1/28 (20130101) G06F 1/30 (20130101) G06F 17/40 (20130101) G06F 17/5036 (20130101) Original (OR) Class G06F 17/5045 (20130101) G06F 17/5063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529059 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Fu-Chung Huang (Bellevue, Washington); Gordon Wetzstein (Cambridge, Massachusetts); Brian Barsky (Berkeley, California); Ramesh Raskar (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for compensating for at least one optical aberration in a vision system of a viewer viewing a display. Image data for an image to be displayed is received, at least one parameter related to at least one optical aberration in the vision system of a viewer is received and an aberration compensated image to be displayed is computed based on the at least one received parameter related to the vision system of a viewer and on at least one characteristic of the light field element. The aberration compensated image is displayed on the display medium, such that when a viewer whose vision system has the at least one optical aberration views the aberration compensated image displayed on the display medium through a light field element, the aberration compensated image appears to the viewer with the at least one aberration reduced or eliminated. |
| FILED | Tuesday, August 11, 2015 |
| APPL NO | 14/823906 |
| ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/0025 (20130101) G02B 27/0075 (20130101) G02B 27/2214 (20130101) Image Data Processing or Generation, in General G06T 5/003 (20130101) Original (OR) Class G06T 2207/20172 (20130101) G06T 2210/36 (20130101) G06T 2210/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529440 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Jiaxiang Zhang (Troy, New York); John T. Wen (Melrose, New York); Agung Julius (Poestenkill, New York) |
| ABSTRACT | Method, system and computer program product are provided for estimating a circadian phase of a subject by: obtaining a sensed biological signal for the subject; and using, by one or more processors, adaptive frequency tracking to adaptively estimate the circadian phase of the subject from the sensed biological signal. Circadian phase estimation may be accelerated by providing a feedback loop for the adaptive frequency tracking, which utilizes, in part, a circadian phase model in automatically ascertaining a phase correction for the adaptive frequency tracking. The circadian phase estimation may be used in automatically constructing a light-based circadian rhythm model for the subject using a linear parameter-varying (LPV) formulation, and once constructed, the circadian rhythm model for the subject may be used to provide light-based circadian rhythm regulation. |
| FILED | Tuesday, June 04, 2013 |
| APPL NO | 14/405973 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4857 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0618 (20130101) A61N 2005/0626 (20130101) Computer Systems Based on Specific Computational Models G06N 7/02 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529564 | Narayan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Jagdish Narayan (Raleigh, North Carolina) |
| ABSTRACT | Using processes disclosed herein, materials and structures are created and used. For example, processes can include melting boron nitride or amorphous carbon into an undercooled state followed by quenching. Exemplary new materials disclosed herein can be ferromagnetic and/or harder than diamond. Materials disclosed herein may include dopants in concentrations exceeding thermodynamic solubility limits. A novel phase of solid carbon has structure different than diamond and graphite. |
| FILED | Monday, August 08, 2016 |
| APPL NO | 15/230956 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/064 (20130101) C01B 21/0648 (20130101) C01B 32/05 (20170801) C01B 32/25 (20170801) C01B 32/188 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/02 (20130101) C01P 2004/03 (20130101) C01P 2006/40 (20130101) C01P 2006/42 (20130101) C01P 2006/90 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/28 (20130101) C23C 14/0605 (20130101) C23C 14/0647 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 1/023 (20130101) C30B 13/10 (20130101) C30B 13/24 (20130101) C30B 19/08 (20130101) C30B 23/025 (20130101) C30B 23/066 (20130101) C30B 29/04 (20130101) C30B 29/62 (20130101) C30B 29/403 (20130101) C30B 31/06 (20130101) C30B 31/22 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/032 (20130101) G01R 33/1284 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/42 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/0259 (20130101) Original (OR) Class H01L 21/268 (20130101) H01L 21/02527 (20130101) H01L 21/02595 (20130101) H01L 21/02603 (20130101) H01L 21/02609 (20130101) H01L 21/02631 (20130101) H01L 21/02686 (20130101) H01L 43/10 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 15/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529870 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sang Eon Han (Albuquerque, New Mexico); Seok Jun Han (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Sang Eon Han (Albuquerque, New Mexico); Seok Jun Han (Albuquerque, New Mexico) |
| ABSTRACT | A photonic infrared detector having at least one metal layer having a broad-band IR absorption and the detector is configured to enable light to make a plurality of passes within a c-Si substrate. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 15/693115 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/028 (20130101) H01L 31/108 (20130101) H01L 31/1804 (20130101) H01L 31/02161 (20130101) H01L 31/02164 (20130101) Original (OR) Class H01L 31/02327 (20130101) H01L 31/02363 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529938 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Hong Koo Kim (Wexford, Pennsylvania); Daud Hasan Emon (Hillsboro, Oregon) |
| ABSTRACT | Various light emitting diode device embodiments that include emissive material elements, e.g., core-shell quantum dots, that are either (i) provided in nanoscale holes provided in an insulating layer positioned between an electron supply/transport layer and a hole supply/transport layer, or (ii) provided on a suspension layer positioned above and covering a nanoscale hole in such an insulating layer. Also, various methods of making such light emitting diode devices, including lithographic and non-lithographic methods. |
| FILED | Wednesday, May 16, 2018 |
| APPL NO | 15/980868 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/50 (20130101) Original (OR) Class H01L 51/56 (20130101) H01L 51/0096 (20130101) H01L 51/502 (20130101) H01L 51/5004 (20130101) H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 51/5096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530321 | Morgan |
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| FUNDED BY |
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| APPLICANT(S) | Associated Universities, Inc. (Washington, District of Columbia) |
| ASSIGNEE(S) | Associated Universities, Inc. (Washington, District of Columbia) |
| INVENTOR(S) | Matthew A. Morgan (Earlysville, Virginia) |
| ABSTRACT | Reflectionless electronic filters, as well as a method for designing such filters is disclosed, along with a method of realizing critical subcircuits within those filters that mimic the behavior of tee- and pi-networks having negative elements, though the critical subcircuits themselves are entirely passive. This allows a much broader range of transmission responses to be realized in reflectionless form than in the prior art, and especially with lower ripple factor for deeper rejection in equal-ripple Chebyshev responses. Reflectionless filters preferably function by absorbing the stop-band portion of the spectrum rather than reflecting it back to the source, which has significant advantages in many different applications. |
| FILED | Tuesday, April 02, 2019 |
| APPL NO | 16/372626 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/06 (20130101) H03H 7/38 (20130101) H03H 7/065 (20130101) Original (OR) Class H03H 7/0115 (20130101) H03H 7/0138 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530392 | Reynwar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Codelucida, Inc. (Tucson, Arizona) |
| ASSIGNEE(S) | Codelucida, Inc. (Tucson, Arizona) |
| INVENTOR(S) | Benedict J. Reynwar (Tucson, Arizona); David Declercq (Tucson, Arizona); Shiva Kumar Planjery (Tucson, Arizona) |
| ABSTRACT | This invention presents a method and apparatus for vertical layered finite alphabet iterative decoding of low-density parity-check codes (LDPC) which operate on parity check matrices that consist of blocks of sub-matrices. The iterative decoding involves passing messages between variable nodes and check nodes of the Tanner graph that associated with one or more sub-matrices constitute decoding blocks, and the messages belong to a finite alphabet. Various embodiments for the method and apparatus of the invention are presented that can achieve very high throughputs with low hardware resource usage and power. |
| FILED | Monday, July 30, 2018 |
| APPL NO | 16/049724 |
| ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/114 (20130101) H03M 13/116 (20130101) H03M 13/118 (20130101) Original (OR) Class H03M 13/1108 (20130101) H03M 13/1111 (20130101) H03M 13/1117 (20130101) H03M 13/6577 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10531553 | Ruzic et al. |
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| FUNDED BY |
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| APPLICANT(S) | Starfire Industries, LLC (Champaign, Illinois) |
| ASSIGNEE(S) | STARFIRE INDUSTRIES, LLC (Champaign, Illinois) |
| INVENTOR(S) | David N. Ruzic (Pesotum, Illinois); Robert A. Stubbers (Champaign, Illinois); Brian E. Jurczyk (Champaign, Illinois) |
| ABSTRACT | Systems and methods are described herein for generating surface-wave plasmas capable of simultaneously achieving high density with low temperature and planar scalability. A key feature of the invention is reduced damage to objects in contact with the plasma due to the lack of an RF bias; allowing for damage free processing. The preferred embodiment is an all-in-one processing reactor suitable for photovoltaic cell manufacturing, performing saw-damage removal, oxide stripping, deposition, doping and formation of hetero structures. The invention is scalable for atomic-layer deposition, etching, and other surface interaction processes. |
| FILED | Thursday, January 04, 2018 |
| APPL NO | 15/862354 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/67017 (20130101) H01L 21/67155 (20130101) H01L 31/18 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) Original (OR) Class H05H 2001/463 (20130101) H05H 2001/4615 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10525146 | Rajh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tijana Rajh (Naperville, Illinois); Elena A. Rozhkova (Lemont, Illinois); Harry C. Fry (Lincolnwood, Illinois); Nada Dimitrijevic (Downers Grove, Illinois); Tamara Koritarov (Naperville, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Tijana Rajh (Naperville, Illinois); Elena A. Rozhkova (Lemont, Illinois); Harry C. Fry (Lincolnwood, Illinois); Nada Dimitrijevic (Downers Grove, Illinois); Tamara Koritarov (Naperville, Illinois); Bartosz Gryzbowski (Evanston, Illinois) |
| ABSTRACT | A nanostructure comprises a MOX NP and a bidentate ligand on a surface of the MOX NP. A cancer recognition molecule is covalent coupled to the surface of the MOX NP via the bidentate ligand. A biocatalyst is also coupled to the surface of the MOX nanoparticle via the bidentate ligand. The cancer recognition molecule includes a structure configured to selectively recognize a corresponding antigen on a surface of a cancer cell and bind to the antigen. The biocatalyst is structured to selectively catalyze the oxidation of a light emitting compound to produce photons. The photons transform the MOX NPs into an excited state such that the MOX NPs generate reactive oxygen species (ROS) in the vicinity of the cancer cells in the excited state. The reactive oxygen species lyse or cause apoptosis in the cancer cells in situ. The biocatalyst includes luciferase and the light emitting compound includes luciferin. |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 16/385519 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6863 (20170801) Original (OR) Class A61K 47/6923 (20170801) A61K 49/12 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525285 | Friedman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Integrated Sensors, LLC (Ottawa Hills, Ohio) |
| ASSIGNEE(S) | Integrated Sensors, LLC (Ottawa Hills, Ohio) |
| INVENTOR(S) | Peter S. Friedman (Ottawa Hills, Ohio) |
| ABSTRACT | A transmissive ionizing-radiation beam monitoring system includes an enclosure structure including an entrance window and an exit window to an incident ionizing-radiation beam, where the entrance window and the exit window are highly transmissive. The system further includes a thin scintillator within the enclosure structure that is directly in an incident ionizing-radiation beam path and transmissive to the incident radiation beam and an ultraviolet (“UV”) illumination source within the enclosure structure facing the scintillator for internal system calibration. Embodiments further include a UV photosensor within the enclosure structure positioned to monitor and calibrate the UV illumination source and a machine vision camera within the enclosure structure that includes a lens which views the scintillator through a close proximity mirror including a folded optical axis system located to a side of the scintillator. |
| FILED | Thursday, August 01, 2019 |
| APPL NO | 16/529200 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101) A61N 5/1045 (20130101) A61N 5/1048 (20130101) A61N 5/1049 (20130101) A61N 5/1064 (20130101) A61N 5/1067 (20130101) Original (OR) Class A61N 5/1077 (20130101) A61N 2005/1059 (20130101) A61N 2005/1087 (20130101) Measurement of Nuclear or X-radiation G01T 1/29 (20130101) G01T 1/1612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10525434 | Weissman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| ASSIGNEE(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| INVENTOR(S) | Jeffrey Weissman (Guilford, Connecticut) |
| ABSTRACT | A chemical reactor for use in a chemical process wherein a reactant and/or a target product is prone to produce undesirable byproducts through secondary reactions. The reactor is configured with a first flow passage for passing a flow of an overly reactive reactant; a permeable first wall for controlled flow of the overly reactive reactant into a second flow passage providing a flow of a second reactant; a permeable second wall having a catalyst supported on an inner surface thereof for catalyzing reaction of the reactants flowing in the second flow passage; the permeable second wall passing through a flow containing the target product; and a non-permeable third wall defining a third flow passage for exiting the product mixture. The reactor can be employed in selective oxidation, oxidative dehydrogenation, and alkylation processes to reduce the formation of byproducts. |
| FILED | Monday, July 30, 2018 |
| APPL NO | 16/048465 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/002 (20130101) Original (OR) Class B01J 19/244 (20130101) B01J 19/248 (20130101) B01J 19/2475 (20130101) B01J 2219/00076 (20130101) B01J 2219/00245 (20130101) B01J 2219/2401 (20130101) B01J 2219/2475 (20130101) Acyclic or Carbocyclic Compounds C07C 2/58 (20130101) C07C 2/84 (20130101) C07C 29/50 (20130101) C07C 2523/34 (20130101) C07C 2529/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526437 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Thomas S. Wilson (Castro Valley, California); Jane P. Bearinger (Berwyn, Pennsylvania) |
| ABSTRACT | New shape memory polymer compositions, methods for synthesizing new shape memory polymers, and apparatus comprising an actuator and a shape memory polymer wherein the shape memory polymer comprises at least a portion of the actuator. A shape memory polymer comprising a polymer composition which physically forms a network structure wherein the polymer composition has shape-memory behavior and can be formed into a permanent primary shape, re-formed into a stable secondary shape, and controllably actuated to recover the permanent primary shape. Polymers have optimal aliphatic network structures due to minimization of dangling chains by using monomers that are symmetrical and that have matching amine and hydroxyl groups providing polymers and polymer foams with clarity, tight (narrow temperature range) single transitions, and high shape recovery and recovery force that are especially useful for implanting in the human body. |
| FILED | Monday, August 14, 2017 |
| APPL NO | 15/676740 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3498 (20130101) A61B 2017/00867 (20130101) A61B 2017/00871 (20130101) A61B 2017/2932 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/08 (20130101) C08G 18/73 (20130101) C08G 18/3203 (20130101) Original (OR) Class C08G 18/3221 (20130101) C08G 18/3271 (20130101) C08G 18/3281 (20130101) C08G 18/3284 (20130101) C08G 18/3287 (20130101) C08G 18/3851 (20130101) C08G 2280/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/0085 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 75/12 (20130101) C08L 75/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526615 | Grunden et al. |
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| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| INVENTOR(S) | Amy Michele Grunden (Holly Springs, North Carolina); Heike Sederoff (Raleigh, North Carolina); Roopa D. Yalamanchili (Cary, North Carolina) |
| ABSTRACT | This invention provides a stably transformed plant, plant part and/or plant cell, comprising a heterologous polynucleotide encoding a superoxide reductase (SOR) from an archaeon species, wherein said stably transformed plant, plant cell, and/or plant part has increased disease resistance. The invention further provides a method of increasing disease resistance in a plant, plant cell, or plant part, comprising: introducing into said plant, plant cell, or plant part a heterologous polynucleotide encoding a superoxide reductase from an archaeon species to produce a stably transformed plant, plant cell, or plant part, thereby producing a plant, plant part, or plant cell having increased disease resistance as compared to a control. Additionally provided are plants, plant parts, and plant cells produced by the methods of the invention, as well as progeny and products produced therefrom. |
| FILED | Friday, December 08, 2017 |
| APPL NO | 15/836465 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0089 (20130101) C12N 15/8279 (20130101) Original (OR) Class C12N 15/8282 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527384 | Hartman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Seth Hartman (Kansas City, Missouri); Erik Timpson (Kansas City, Missouri) |
| ABSTRACT | An electromagnetic launcher with a curved or spiral-shaped, open-ended guideway and conductors for launching a projectile. The projectile, movably retained on or within the guideway, is accelerated along the guideway using electromagnetic forces until it reaches an end of the guideway, then the projectile is launched in a desired direction. The direction of the launch of the projectile is determined by orienting the guideway in the desired direction using an actuator. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/106662 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Weapons for Projecting Missiles Without Use of Explosive or Combustible Propellant Charge; Weapons Not Otherwise Provided for F41B 3/04 (20130101) F41B 6/003 (20130101) Original (OR) Class F41B 6/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527412 | Thorpe et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bridger Photonics, Inc. (Bozeman, Montana) |
| ASSIGNEE(S) | Bridger Photonics, Inc. (Bozeman, Montana) |
| INVENTOR(S) | Michael Thorpe (Bozeman, Montana); Aaron Kreitinger (Bozeman, Montana); Stephen Crouch (Bozeman, Montana) |
| ABSTRACT | Measurement approaches and data analysis methods are disclosed for combining 3D topographic data with spatially-registered gas concentration data to increase the efficiency of gas monitoring and leak detection tasks. Here, the metric for efficiency is defined as reducing the measurement time required to achieve the detection, or non-detection, of a gas leak with a desired confidence level. Methods are presented for localizing and quantifying detected gas leaks. Particular attention is paid to the combination of 3D spatial data with path-integrated gas concentration measurements acquired using remote gas sensing technologies, as this data can be used to determine the path-averaged gas concentration between the sensor and points in the measurement scene. Path-averaged gas concentration data is useful for finding and quantifying localized regions of elevated (or anomalous) gas concentration making it ideal for a variety of applications including: oil and gas pipeline monitoring, facility leak and emissions monitoring, and environmental monitoring. |
| FILED | Wednesday, October 05, 2016 |
| APPL NO | 15/285787 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 21/20 (20130101) Original (OR) Class Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 15/00 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/28 (20130101) G01M 3/38 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) G01N 21/53 (20130101) G01N 2021/1793 (20130101) G01N 2021/1795 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/00 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527492 | Bouzid |
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| FUNDED BY |
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| APPLICANT(S) | Li-Cor, Inc. (Lincoln, Nebraska) |
| ASSIGNEE(S) | LI-COR, Inc. (Lincoln, Nebraska) |
| INVENTOR(S) | Ahmed Bouzid (Lincoln, Nebraska) |
| ABSTRACT | Systems and methods for controlling optical feedback in an optical system having a radiation source optically coupled via mode matching optics with a resonant optical cavity. The cavity includes at least two cavity mirrors, one of which is a cavity coupling mirror, and has a plurality of optical resonance cavity modes, wherein the radiation source emits a beam of continuous wave radiation and is capable of being scanned whereby a mean optical frequency of the continuous wave radiation beam is adjustable over a range of frequencies, wherein the radiation source is responsive to optical feedback radiation emerging from the cavity, and wherein the mode matching optics couples the beam of continuous wave radiation to the cavity via the cavity coupling mirror. The radiation source and the mode matching optics are aligned so that a mode fill ratio is reduced relative to a maximum mode fill ratio, wherein for the maximum mode-fill ratio the laser beam is coupled with a fundamental cavity mode. |
| FILED | Tuesday, May 16, 2017 |
| APPL NO | 15/596695 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/021 (20130101) G01J 3/027 (20130101) G01J 3/0237 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) G01N 2201/0636 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 17/004 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0071 (20130101) H01S 5/0656 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527682 | DeRego |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Paul Jeffrey DeRego (Albuquerque, New Mexico) |
| ABSTRACT | A system and method for detecting a magnetic field generated by a magnetic field source located in a circuit. A magnetometer array generates data regarding an activity of the source. A computing device executes a magnetic beamforming data processing program including a hybrid model which receives data generated by the array and detects the magnetic field generated by the source. The hybrid model is based on a weighted sum of contributions to the magnetic field, which include a first modelled magnetic field contribution generated by a current dipole aligned with an axis of the source, and a second modelled magnetic field contribution generated by a loop current flowing around the axis. Weighting factors are applied to the modelled fields, and then the weighted modelled fields are summed to produce the hybrid model. The weighting factors can be adjusted to emphasize the contribution of one modelled field over the other. |
| FILED | Thursday, September 27, 2018 |
| APPL NO | 16/144457 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/02 (20130101) G01R 33/0023 (20130101) Original (OR) Class G01R 33/0094 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528582 | Stolte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California) |
| INVENTOR(S) | Chris Stolte (Seattle, Washington); Diane L. Tang (Palo Alto, California); Patrick Hanrahan (Portola Valley, California) |
| ABSTRACT | An exemplary method of displaying a data visualization includes displaying a graphical user interface that includes three distinct regions, and receiving user actions to associate three different fields with three different shelves, including a shelf that defines colors of data marks. The method also includes generating, in accordance with the received user actions, data marks to be displayed in a data visualization, each data mark corresponding to a respective retrieved tuple of data from a multidimensional database, where (i) each data mark has an x-position defined according to data for a first field in the respective tuple, (ii) each data mark has a y-position defined according to data for a second field in the respective tuple, and (iii) each data mark has a color assigned according to data for a third field in the respective tuple. The method also includes displaying a data visualization that includes the generated data marks. |
| FILED | Tuesday, August 07, 2018 |
| APPL NO | 16/056819 |
| ART UNIT | 2166 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/04842 (20130101) G06F 3/04847 (20130101) G06F 16/26 (20190101) G06F 16/212 (20190101) G06F 16/221 (20190101) G06F 16/248 (20190101) Original (OR) Class G06F 16/252 (20190101) G06F 16/282 (20190101) G06F 16/283 (20190101) G06F 16/2282 (20190101) G06F 17/245 (20130101) G06F 17/246 (20130101) G06F 2216/03 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 707/954 (20130101) Y10S 707/956 (20130101) Y10S 707/959 (20130101) Y10S 707/99942 (20130101) Y10S 707/99943 (20130101) Y10S 707/99944 (20130101) Y10S 707/99945 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528583 | Stolte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California) |
| INVENTOR(S) | Chris Stolte (Seattle, Washington); Diane L. Tang (Palo Alto, California); Patrick Hanrahan (Portola Valley, California) |
| ABSTRACT | A method is performed at a computer. The computer retrieves a dataset having a plurality of fields, including a first field and a second field. The computer displays a graphical user interface, including a first region displaying the plurality of fields from the dataset, a second region having a plurality of shelves determined according to a user-selected data visualization type, and a third region for displaying one or more data visualizations. The computer receives user actions to drop the first field on a first shelf and to drop the second field on a second shelf. The first and second shelves define positional attributes of data marks. The computer displays a data visualization in the third region. Each data mark has a position in the data visualization determined according to the first shelf, a data value for the first field, the second shelf, and a data value for the second field. |
| FILED | Thursday, September 20, 2018 |
| APPL NO | 16/137457 |
| ART UNIT | 2166 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/04842 (20130101) G06F 3/04847 (20130101) G06F 16/26 (20190101) G06F 16/212 (20190101) G06F 16/221 (20190101) G06F 16/248 (20190101) Original (OR) Class G06F 16/252 (20190101) G06F 16/282 (20190101) G06F 16/283 (20190101) G06F 16/2282 (20190101) G06F 17/245 (20130101) G06F 17/246 (20130101) G06F 2216/03 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 707/954 (20130101) Y10S 707/956 (20130101) Y10S 707/959 (20130101) Y10S 707/99942 (20130101) Y10S 707/99943 (20130101) Y10S 707/99944 (20130101) Y10S 707/99945 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528584 | Stolte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California) |
| INVENTOR(S) | Chris Stolte (Seattle, Washington); Diane L. Tang (Palo Alto, California); Patrick Hanrahan (Portola Valley, California) |
| ABSTRACT | An example method of displaying a data visualization includes displaying a graphical user interface that includes three distinct regions, and receiving user actions to associate two different fields with two different shelves. The method also includes generating, in accordance with the received user actions, data marks to be displayed in a data visualization, each data mark corresponding to a respective retrieved tuple of data from a multidimensional database, where (i) each data mark has an x-position defined according to data for a first field in the respective tuple and (ii) each data mark has a y-position defined according to data for a second field in the respective tuple. The method also includes displaying a data visualization that includes the generated data marks. |
| FILED | Friday, December 14, 2018 |
| APPL NO | 16/220240 |
| ART UNIT | 2166 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/04842 (20130101) G06F 3/04847 (20130101) G06F 16/26 (20190101) G06F 16/212 (20190101) G06F 16/221 (20190101) G06F 16/248 (20190101) Original (OR) Class G06F 16/252 (20190101) G06F 16/282 (20190101) G06F 16/283 (20190101) G06F 16/2282 (20190101) G06F 17/245 (20130101) G06F 17/246 (20130101) G06F 2216/03 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 707/954 (20130101) Y10S 707/956 (20130101) Y10S 707/959 (20130101) Y10S 707/99942 (20130101) Y10S 707/99943 (20130101) Y10S 707/99944 (20130101) Y10S 707/99945 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10528687 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Regents of the University of Minnesota (Minneapolis, Minnesota); ETH Zürich (Zürich, Switzerland) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); ETH Zürich (Zürich, Switzerland) |
| INVENTOR(S) | Brian Benjamin Johnson (Denver, Colorado); Nathan Ainsworth (Brown Deer, Wisconsin); Sairaj Vijaykumar Dhople (Minneapolis, Minnesota); Mohit Sinha (St. Paul, Minnesota); Florian Anton Dörfler (Zürich, Switzerland) |
| ABSTRACT | Virtual oscillator control systems, devices, and techniques are provided. One example device includes a processor configured to implement a virtual oscillator circuit and output an oscillating waveform based on the virtual oscillator circuit and power electronics operatively coupled to the processor and configured to convert, based on the oscillating waveform, direct current (DC) electricity to alternating current (AC) electricity. The processor may be further configured to extract, from the virtual oscillator circuit, a virtual current based on an output current of the AC electricity, and output the oscillating waveform further based on an input voltage of the DC electricity. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 15/581824 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/2513 (20130101) G01R 21/133 (20130101) G01R 31/42 (20130101) G01R 35/04 (20130101) Electric Digital Data Processing G06F 1/28 (20130101) G06F 1/30 (20130101) G06F 17/40 (20130101) G06F 17/5036 (20130101) Original (OR) Class G06F 17/5045 (20130101) G06F 17/5063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529458 | Kanuch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BWXT mPower, Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | BWXT mPower, Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | David J Kanuch (Charlotte, North Carolina); Paul P. DiFilipo (Lynchburg, Virginia) |
| ABSTRACT | A nuclear reactor includes a nuclear reactor core comprising fissile material disposed in a reactor pressure vessel having vessel penetrations that exclusively carry flow into the nuclear reactor and at least one vessel penetration that carries flow out of the nuclear reactor. An integral isolation valve (IIV) system includes passive IIVs each comprising a check valve built into a forged flange and not including an actuator, and one or more active IIVs each comprising an active valve built into a forged flange and including an actuator. Each vessel penetration exclusively carrying flow into the nuclear reactor is protected by a passive IIV whose forged flange is directly connected to the vessel penetration. Each vessel penetration carrying flow out of the nuclear reactor is protected by an active IIV whose forged flange is directly connected to the vessel penetration. Each active valve may be a normally closed valve. |
| FILED | Tuesday, July 22, 2014 |
| APPL NO | 14/337268 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 9/00 (20130101) G21C 13/02 (20130101) G21C 15/182 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529677 | Yudanov |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Dmitri Yudanov (Austin, Texas) |
| ABSTRACT | Various chip stack power delivery circuits are disclosed. In one aspect, an apparatus is provided that includes a stack of semiconductor chips that has an uppermost semiconductor chip and a lowermost semiconductor chip. A heat spreader is positioned on the uppermost semiconductor chip. A power transfer circuit is configured to transfer electric power from the heat spreader to the uppermost semiconductor chip. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 15/965425 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/34 (20130101) H01L 23/645 (20130101) Original (OR) Class H01L 23/3157 (20130101) H01L 23/5286 (20130101) H01L 24/09 (20130101) H01L 24/17 (20130101) H01L 24/49 (20130101) H01L 24/73 (20130101) H01L 25/0657 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529971 | Visco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Bruce D. Katz (Moraga, California); Yevgeniy S. Nimon (Danville, California); Lutgard C. De Jonghe (Lafayette, California) |
| ABSTRACT | Active metal and active metal intercalation electrode structures and battery cells having ionically conductive protective architecture including an active metal (e.g., lithium) conductive impervious layer separated from the electrode (anode) by a porous separator impregnated with a non-aqueous electrolyte (anolyte). This protective architecture prevents the active metal from deleterious reaction with the environment on the other (cathode) side of the impervious layer, which may include aqueous or non-aqueous liquid electrolytes (catholytes) and/or a variety electrochemically active materials, including liquid, solid and gaseous oxidizers. Safety additives and designs that facilitate manufacture are also provided. |
| FILED | Thursday, April 13, 2017 |
| APPL NO | 15/487364 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/06 (20130101) H01G 11/52 (20130101) H01G 11/58 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1673 (20130101) Original (OR) Class H01M 2/1686 (20130101) H01M 4/13 (20130101) H01M 4/366 (20130101) H01M 4/587 (20130101) H01M 4/628 (20130101) H01M 6/34 (20130101) H01M 8/065 (20130101) H01M 10/36 (20130101) H01M 10/052 (20130101) H01M 10/0562 (20130101) H01M 12/08 (20130101) H01M 2004/027 (20130101) H01M 2300/0085 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Y02E 60/122 (20130101) Y02E 60/128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529975 | Song et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | West Virginia University (Morgantown, West Virginia) |
| ASSIGNEE(S) | West Virginia University (Morgantown, West Virginia) |
| INVENTOR(S) | Xueyan Song (Morgantown, West Virginia); Yun Chen (Morgantown, West Virginia); Kirk Gerdes (Morgantown, West Virginia); Shiwoo Lee (Morgantown, West Virginia) |
| ABSTRACT | One embodiment includes forming surface-modifying phases on a surface of a functional electrode via atomic layer deposition and controlling the chemistry of constituent phases, the crystalline nature of the constituent phases and the thickness of the surface-modifying phase via the atomic layer deposition such that the thickness is between about 2 nm to about 200 nm. The surface-modifying phases enhances the performance of electrocatalytic activity of the functional electrode and the device. |
| FILED | Friday, July 31, 2015 |
| APPL NO | 14/814881 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0428 (20130101) Original (OR) Class H01M 4/8626 (20130101) H01M 4/8878 (20130101) H01M 8/1213 (20130101) H01M 8/1246 (20130101) H01M 2008/1293 (20130101) H01M 2300/0074 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/525 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/56 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530120 | Kirchner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KM Labs Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | Kapteyn-Murnane Laboratories, Inc. (Boulder, Colorado) |
| INVENTOR(S) | Matthew S. Kirchner (Westminster, Colorado); Sterling Backus (Erie, Colorado) |
| ABSTRACT | Direct diode-pumped Ti:sapphire laser amplifiers use fiber-coupled laser diodes as pump beam sources. The pump beam may be polarized or non-polarized. Light at wavelengths below 527 nm may be used in cryogenic configurations. Multiple diode outputs may be polarization or spectrally combined. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/442000 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/025 (20130101) H01S 3/042 (20130101) H01S 3/235 (20130101) H01S 3/0407 (20130101) H01S 3/0813 (20130101) H01S 3/0941 (20130101) H01S 3/1028 (20130101) H01S 3/1106 (20130101) H01S 3/1625 (20130101) Original (OR) Class H01S 3/1636 (20130101) H01S 3/2308 (20130101) H01S 3/08072 (20130101) H01S 3/09408 (20130101) H01S 3/09415 (20130101) H01S 3/10007 (20130101) H01S 3/10061 (20130101) H01S 3/094084 (20130101) H01S 5/02284 (20130101) H01S 5/4012 (20130101) H01S 5/4025 (20130101) H01S 5/32341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530362 | Voss et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lars Voss (Livermore, California); Mihail Bora (Livermore, California); Adam Conway (Livermore, California); Paulius Vytautas Grivickas (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermroe, California) |
| INVENTOR(S) | Lars Voss (Livermore, California); Mihail Bora (Livermore, California); Adam Conway (Livermore, California); Paulius Vytautas Grivickas (Livermore, California) |
| ABSTRACT | A total internal reflection photoconductive switch and method of activating such a switch, where the switch includes a pair of electrodes on opposite sides of a photoconductive material having a substantially-rectangular prism geometry. The substantially-rectangular prism geometry includes four edge facets, two opposing electrode-connection facets separated by the edge facets, and at least one input facet located at a corner of the substantially-rectangular prism geometry that is positioned between two edge facets and the two electrode-connection facets, for receiving light therethrough into the photoconductive material at angles supporting total internal reflection. |
| FILED | Tuesday, November 07, 2017 |
| APPL NO | 15/806243 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/10 (20130101) Pulse Technique H03K 17/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530799 | Neil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Joshua Neil (Jemez Springs, New Mexico); Alexander Kent (Los Alamos, New Mexico); Curtis Hash, Jr. (Santa Fe, New Mexico); Michael Fisk (Los Alamos, New Mexico); Alexander Brugh (Los Alamos, New Mexico); Curtis Storlie (Jemez Springs, New Mexico); Benjamin Uphoff (Los Alamos, New Mexico) |
| ABSTRACT | Non-harmful data mimicking computer network attacks may be inserted in a computer network. Anomalous real network connections may be generated between a plurality of computing systems in the network. Data mimicking an attack may also be generated. The generated data may be transmitted between the plurality of computing systems using the real network connections and measured to determine whether an attack is detected. |
| FILED | Wednesday, October 24, 2018 |
| APPL NO | 16/168956 |
| ART UNIT | 2493 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 5/022 (20130101) G06N 5/045 (20130101) G06N 7/005 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/002 (20130101) H04L 63/1408 (20130101) H04L 63/1416 (20130101) H04L 63/1425 (20130101) Original (OR) Class H04L 63/1433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10531568 | Hatch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Stephen McGarry Hatch (Blue Springs, Missouri); Jonathan Douglas Hatch (Cleveland, Missouri) |
| ABSTRACT | A circuit component decal comprising a transparent sheet and an opaque circuit pattern. The transparent sheet includes opposing top and bottom surfaces and a number of edges. The opaque circuit pattern includes an electronic component footprint and a number of circuit lead paths. The electronic component footprint includes a number of contact points representing the location of leads of the electronic component. The circuit lead paths extend from the contact points to the edges of the transparent sheet. The opaque circuit pattern corresponds to only a section of a complete circuit pattern and is configured to block energy from reaching a first portion of the intermediate substrate when the transparent sheet is positioned on the intermediate substrate so as to form the section of the complete circuit pattern. |
| FILED | Tuesday, January 22, 2019 |
| APPL NO | 16/253362 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/29 (20180101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/048 (20130101) Original (OR) Class H05K 2203/0121 (20130101) H05K 2203/0186 (20130101) H05K 2203/0557 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10525638 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Brice A. Johnson (Federal Way, Washington); Samuel F. Pedigo (Lake Forest Park, Washington); Sayata Ghose (Sammamish, Washington); John Z. Lin (Renton, Washington) |
| ABSTRACT | Closed-loop systems and methods for controlling the temperature at the compaction point as an automated fiber placement (AFP) machine is placing material over complex surface features at varying speeds. The closed-loop system starts with multiple infrared temperature sensors directed at the layup surface in front of the compaction roller and also at the new layup surface behind the compaction roller. These sensors supply direct temperature readings to a control computer, which also receives speed data and a listing of active tows from the AFP machine and is also programmed with the number of plies in the current layup. In accordance with one embodiment, the heater control system uses a proportional-integral-derivative loop to control the temperature at the compaction point (e.g., at the interface of the compaction roller and a newly laid tow) and regulate the heater power to achieve the desired temperature. |
| FILED | Tuesday, August 29, 2017 |
| APPL NO | 15/689703 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0288 (20130101) B29C 35/0805 (20130101) B29C 70/384 (20130101) Original (OR) Class B29C 2035/0822 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526914 | Morin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Bruce L. Morin (Springfield, Massachusetts); Wesley K. Lord (South Glastonbury, Connecticut) |
| ABSTRACT | In accordance with one aspect of the disclosure, a gas turbine engine, method of using and designing such is disclosed. The gas turbine engine may comprise a fan including a plurality of blades, and a variable area fan nozzle. The fan may be configured to have a design point fan tip leading edge relative flow angle βADP, and may be further configured to have an off-design point fan tip leading edge relative flow angle β at an off-design fan operating point. The variable area fan nozzle may be configured to manipulate the amount of air flowing through the fan so that the absolute value of a difference between the design point fan tip leading edge relative flow angle βADP and the off-design point fan tip leading edge relative flow angle β is in a specified range. |
| FILED | Tuesday, March 11, 2014 |
| APPL NO | 14/761689 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 5/141 (20130101) F01D 9/02 (20130101) F01D 17/14 (20130101) F01D 25/04 (20130101) Original (OR) Class Jet-propulsion Plants F02K 1/15 (20130101) F02K 1/16 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/36 (20130101) F05D 2260/96 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527004 | Whitmore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen A. Whitmore (Logan, Utah); Nathan Inkley (Hewitt, Texas); Daniel P. Merkley (Layton, Utah) |
| ASSIGNEE(S) | Utah State University (Logan, Utah) |
| INVENTOR(S) | Stephen A. Whitmore (Logan, Utah); Nathan Inkley (Hewitt, Texas); Daniel P. Merkley (Layton, Utah) |
| ABSTRACT | Devices, methods, and systems for providing a restartable ignition system for a hybrid rocket system. In one embodiment, an ignition device includes a housing and at least two electrodes. The housing includes a first side and a second side and defines a bore with an axis extending therethrough between the first and second sides, the bore defining an internal surface of the housing. The at least two electrodes extend through the housing to the internal surface. The at least two electrodes are configured to be spaced apart so as to provide an electrical potential field along the internal surface between the at least two electrodes. Such housing is formed with and includes multiple flat layers such that the multiple flat layers provide ridges along the internal surface. With this arrangement, the internal surface with the ridges are configured to concentrate an electrical charge upon being subjected to the electrical potential field. |
| FILED | Friday, July 17, 2015 |
| APPL NO | 14/802537 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Jet-propulsion Plants F02K 9/72 (20130101) F02K 9/94 (20130101) Original (OR) Class F02K 9/95 (20130101) Spark Gaps; Overvoltage Arresters Using Spark Gaps; Sparking Plugs; Corona Devices; Generating Ions to be Introduced into Non-enclosed Gases H01T 13/20 (20130101) H01T 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527074 | Corke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Notre Dame du Lac (Notre Dame, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Thomas C. Corke (Granger, Indiana); Flint O. Thomas (Granger, Indiana) |
| ABSTRACT | A plasma plate is used to minimize drag of a fluid flow over an exposed surface. The plasma plate includes a series of plasma actuators positioned on the surface. Each plasma actuator is made of a dielectric separating a first electrode exposed to a fluid flow and a second electrode separated from the fluid flow under the dielectric. A pulsed direct current power supply provides a first voltage to the first electrode and a second voltage to the second electrode. The series of plasma actuators is operably connected to a bus which distribute powers and is positioned to minimize flow disturbances. The plasma actuators are arranged into a series of linear rows such that a velocity component is imparted to the fluid flow. |
| FILED | Thursday, July 27, 2017 |
| APPL NO | 15/662040 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Aeroplanes; Helicopters B64C 23/005 (20130101) B64C 2230/12 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/00 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2270/172 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/12 (20130101) Original (OR) Class F15D 1/0075 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/2406 (20130101) H05H 2001/2412 (20130101) H05H 2001/2437 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527717 | Campbell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Joel F. Campbell (Poquoson, Virginia); Bing Lin (Yorktown, Virginia); Amin R. Nehrir (Yorktown, Virginia) |
| ABSTRACT | Systems, methods, and devices of the present invention use a single Pseudo Noise (PN) code to modulate multiple orthogonal carriers by Binary Phase Shift Keying (BPSK) modulation. The various embodiments enable closely spaced carriers to be modulated with the same periodic PN sequence using BPSK modulation. In this manner, even though the carriers may almost entirely share bandwidth, orthogonality of the carriers may not be lost, enabling the various embodiments to be used with limited bandwidth Intensity Modulated Continuous Wave (IM-CW) Light detection and ranging (Lidar), Radio detection and ranging (Radar), or Sound Navigation and Ranging (Sonar) systems. Additionally, by using orthogonal carriers the various embodiments enable measurements to be made simultaneously, thereby reducing the error compared to systems that require sequential measurements, such as pulsed Lidar systems. |
| FILED | Tuesday, August 04, 2015 |
| APPL NO | 14/817843 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/95 (20130101) G01S 13/325 (20130101) Original (OR) Class G01S 15/325 (20130101) G01S 17/32 (20130101) G01S 17/95 (20130101) Technologies for Adaptation to Climate Change Y02A 90/18 (20180101) Y02A 90/19 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530114 | Stephen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Mark A. Stephen (Catonsville, Maryland); Anthony W. Yu (Spencerville, Maryland); Jeffrey W. Nicholson (Warren, New Jersey) |
| ABSTRACT | The disclosed subject matter relates to a polarization-maintaining very large mode area (PM VLMA) Erbium-doped fiber and a polarization maintaining, Er-doped VLMA amplifier. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 15/691904 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/024 (20130101) G02B 6/02009 (20130101) G02B 6/02052 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0677 (20130101) Original (OR) Class H01S 3/0941 (20130101) H01S 3/1608 (20130101) H01S 3/2391 (20130101) H01S 3/06712 (20130101) H01S 3/06729 (20130101) H01S 3/094003 (20130101) H01S 3/094046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530478 | Kingsbury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ryan Wallace Kingsbury (Cambridge, Massachusetts); Kathleen Michelle Riesing (Cambridge, Massachusetts); Kerri Lynn Cahoy (Lexington, Massachusetts); Tam Nguyen Thuc Nguyen (Cambridge, Massachusetts); David O. Caplan (Westford, Massachusetts) |
| ABSTRACT | Communication bottlenecks, particularly in the downlink direction, are a common problem for many CubeSat developers. As described herein, a CubeSat module for a CubeSat comprises an optical transmitter to transmit data to a remote terminal, a receiver to acquire an optical beacon from a remote terminal, and a fine-pointing module operably and directly coupleable to a coarse-pointing module of the CubeSat. The fine-pointing module is configured to point the optical transmitter toward the remote terminal with an accuracy range that overlaps with an accuracy range of the coarse-pointing module of the CubeSat so as to establish a communications link between the CubeSat and the remote terminal over a low-Earth-orbit (LEO) distance. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/805094 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Transmission H04B 7/18513 (20130101) H04B 7/18515 (20130101) H04B 7/18517 (20130101) H04B 10/118 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530629 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use signal constellations, which have unequally spaced (i.e. ‘geometrically’ shaped) points. In many embodiments, the communication systems use specific geometric constellations that are capacity optimized at a specific SNR. In addition, ranges within which the constellation points of a capacity optimized constellation can be perturbed and are still likely to achieve a given percentage of the optimal capacity increase compared to a constellation that maximizes dmin, are also described. Capacity measures that are used in the selection of the location of constellation points include, but are not limited to, parallel decode (PD) capacity and joint capacity. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 15/826579 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/12 (20130101) A61B 6/503 (20130101) A61B 6/527 (20130101) A61B 6/5235 (20130101) A61B 6/5264 (20130101) A61B 34/20 (20160201) A61B 2017/00703 (20130101) A61B 2034/2051 (20160201) A61B 2090/376 (20160201) A61B 2090/3983 (20160201) Image Data Processing or Generation, in General G06T 7/33 (20170101) G06T 2207/10121 (20130101) G06T 2207/30021 (20130101) G06T 2207/30048 (20130101) Transmission H04B 14/023 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10524455 | Wagoner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of North Carolina at Greensboro (Greensboro, North Carolina) |
| ASSIGNEE(S) | University of North Carolina at Greensboro (Greensboro, North Carolina) |
| INVENTOR(S) | Kaira Wagoner (Greensboro, North Carolina); Olav Rueppell (Greensboro, North Carolina) |
| ABSTRACT | The presently disclosed subject matter provides tritriacontene compositions for inducing hygienic behavior in honey bees; mite-infested brood extract compositions for inducing hygienic behavior in honey bees; methods of inducing hygienic behavior in honey bees; methods of selecting one or more honey bee(s) exhibiting hygienic behavior, and methods for assessing the degree of hygienic behavior within a honey bee colony. |
| FILED | Tuesday, February 19, 2019 |
| APPL NO | 16/279432 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 51/00 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10526299 — Fiber conduit reactor with a heat exchange medium inlet and a heat exchange medium outlet
| US 10526299 | Massingill |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chemtor, LP (San Marcos, Texas) |
| ASSIGNEE(S) | Chemtor, LP (San Marcos, Texas) |
| INVENTOR(S) | John Lee Massingill (San Marcos, Texas) |
| ABSTRACT | An apparatus includes a conduit with two process fluid inlets at one end of the conduit, one process fluid outlet at an opposing end, a heat exchange medium inlet, and a heat exchange medium outlet. One of the fluid inlets includes a tube extending into the conduit and a perforated node at the end of the tube, and the other of the fluid inlets is arranged up stream of the perforated node. The apparatus further includes hollow tubes positioned longitudinally within the conduit between the two process fluid inlets, the process fluid outlet, the heat exchange medium inlet and the heat exchange medium outlet. In addition, the apparatus includes a collection vessel positioned proximate the fluid outlet and fibers extending through each of the hollow tubes, wherein one end of the fibers is secured to the perforated node and the other end of the fibers extends into the collection vessel. |
| FILED | Monday, August 05, 2019 |
| APPL NO | 16/532199 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 11/0449 (20130101) B01D 11/0453 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 14/00 (20130101) B01J 19/2415 (20130101) B01J 19/2475 (20130101) B01J 19/2495 (20130101) B01J 2219/24 (20130101) B01J 2219/00085 (20130101) B01J 2219/00599 (20130101) B01J 2219/3322 (20130101) Acyclic or Carbocyclic Compounds C07C 41/14 (20130101) C07C 41/16 (20130101) C07C 67/03 (20130101) Heterocyclic Compounds C07D 301/28 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/022 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/026 (20130101) C10L 2200/0476 (20130101) C10L 2270/026 (20130101) Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom C11C 3/04 (20130101) C11C 3/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526633 | Ramasamy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| INVENTOR(S) | Ramaraja P. Ramasamy (Watkinsville, Georgia); Yi Fang (Athens, Georgia) |
| ABSTRACT | Provided herein are plant/plant pathogen volatile compound electrochemical sensors, plant/plant pathogen volatile detection systems, and methods for detecting stress-induced plant volatile compounds and/or a plant-pathogen emitted volatile compounds. |
| FILED | Friday, April 15, 2016 |
| APPL NO | 15/566438 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/005 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3277 (20130101) G01N 27/3278 (20130101) G01N 33/025 (20130101) G01N 33/0047 (20130101) G01N 33/0098 (20130101) G01N 33/483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP31316 | NeSmith |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | D. Scott NeSmith (Molena, Georgia) |
| ABSTRACT | The new variety ‘TH-1321’ ripens around mid-April in southeastern Georgia. The fruit of the new variety ‘TH-1321’ are very large, firm, have good flavor and scar. The new variety ‘TH-1321’ is vigorous with an estimated chilling requirement of about 50 to 100 hours at or below approximately 7° C. The asexually reproduced variety is reliably propagated vegetatively. |
| FILED | Thursday, January 17, 2019 |
| APPL NO | 16/350824 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/36 (20180501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10525285 | Friedman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Integrated Sensors, LLC (Ottawa Hills, Ohio) |
| ASSIGNEE(S) | Integrated Sensors, LLC (Ottawa Hills, Ohio) |
| INVENTOR(S) | Peter S. Friedman (Ottawa Hills, Ohio) |
| ABSTRACT | A transmissive ionizing-radiation beam monitoring system includes an enclosure structure including an entrance window and an exit window to an incident ionizing-radiation beam, where the entrance window and the exit window are highly transmissive. The system further includes a thin scintillator within the enclosure structure that is directly in an incident ionizing-radiation beam path and transmissive to the incident radiation beam and an ultraviolet (“UV”) illumination source within the enclosure structure facing the scintillator for internal system calibration. Embodiments further include a UV photosensor within the enclosure structure positioned to monitor and calibrate the UV illumination source and a machine vision camera within the enclosure structure that includes a lens which views the scintillator through a close proximity mirror including a folded optical axis system located to a side of the scintillator. |
| FILED | Thursday, August 01, 2019 |
| APPL NO | 16/529200 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101) A61N 5/1045 (20130101) A61N 5/1048 (20130101) A61N 5/1049 (20130101) A61N 5/1064 (20130101) A61N 5/1067 (20130101) Original (OR) Class A61N 5/1077 (20130101) A61N 2005/1059 (20130101) A61N 2005/1087 (20130101) Measurement of Nuclear or X-radiation G01T 1/29 (20130101) G01T 1/1612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10526299 — Fiber conduit reactor with a heat exchange medium inlet and a heat exchange medium outlet
| US 10526299 | Massingill |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chemtor, LP (San Marcos, Texas) |
| ASSIGNEE(S) | Chemtor, LP (San Marcos, Texas) |
| INVENTOR(S) | John Lee Massingill (San Marcos, Texas) |
| ABSTRACT | An apparatus includes a conduit with two process fluid inlets at one end of the conduit, one process fluid outlet at an opposing end, a heat exchange medium inlet, and a heat exchange medium outlet. One of the fluid inlets includes a tube extending into the conduit and a perforated node at the end of the tube, and the other of the fluid inlets is arranged up stream of the perforated node. The apparatus further includes hollow tubes positioned longitudinally within the conduit between the two process fluid inlets, the process fluid outlet, the heat exchange medium inlet and the heat exchange medium outlet. In addition, the apparatus includes a collection vessel positioned proximate the fluid outlet and fibers extending through each of the hollow tubes, wherein one end of the fibers is secured to the perforated node and the other end of the fibers extends into the collection vessel. |
| FILED | Monday, August 05, 2019 |
| APPL NO | 16/532199 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 11/0449 (20130101) B01D 11/0453 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 14/00 (20130101) B01J 19/2415 (20130101) B01J 19/2475 (20130101) B01J 19/2495 (20130101) B01J 2219/24 (20130101) B01J 2219/00085 (20130101) B01J 2219/00599 (20130101) B01J 2219/3322 (20130101) Acyclic or Carbocyclic Compounds C07C 41/14 (20130101) C07C 41/16 (20130101) C07C 67/03 (20130101) Heterocyclic Compounds C07D 301/28 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/022 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/026 (20130101) C10L 2200/0476 (20130101) C10L 2270/026 (20130101) Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom C11C 3/04 (20130101) C11C 3/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527920 | Wo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DHPC Technologies, Inc. (Woodbridge, New Jersey) |
| ASSIGNEE(S) | DHPC Technologies, Inc. (Woodbridge, New Jersey) |
| INVENTOR(S) | Yei Wo (East Brunswick, New Jersey); Bruce P. Boczar (Trevose, Pennsylvania); Richard Gifford (Toms River, New Jersey); Joseph M. Aletta (Jackson, New Jersey) |
| ABSTRACT | A system, method, and device for simulating an emission signature, which contains representative intensity, temporal, and spectral emission profiles of a weapon system or weapon platform for the purpose of testing an optical detection device. A projection system optically projects the emission signature. A projection screen is provided that has a concave curvature. The concave curvature possesses a first focal point and a second focal point. Any light emanating from the second focal toward the projection screen is reflected by the projection screen toward the first focal point. The projection system is positioned at the second focal point and the optical detection system is positioned at the first focal point. In this manner, the emission signature projected by the projector system is redirected to the optical detection system. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/297538 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/2221 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 21/56 (20130101) G03B 21/58 (20130101) G03B 21/60 (20130101) Original (OR) Class G03B 21/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10530127 | Deppe |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Dennis G. Deppe (Oviedo, Florida) |
| ABSTRACT | A semiconductor vertical light source includes upper and lower mirrors with an active region in between, an inner mode confinement region, and an outer current blocking region that includes a common epitaxial layer including an epitaxially regrown interface between the active region and upper mirror. A conducting channel including acceptors is in the inner mode confinement region. The current blocking region includes a first impurity doped region with donors between the epitaxially regrown interface and active region, and a second impurity doped region with acceptors between the first doped region and lower mirror. The outer current blocking region provides a PNPN current blocking region that includes the upper mirror or a p-type layer, first doped region, second doped region, and lower mirror or an n-type layer. The first and second impurity doped region force current flow into the conducting channel during normal operation of the light source. |
| FILED | Thursday, June 21, 2018 |
| APPL NO | 16/014305 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/183 (20130101) H01S 5/305 (20130101) H01S 5/323 (20130101) H01S 5/2018 (20130101) H01S 5/2054 (20130101) H01S 5/2059 (20130101) H01S 5/3013 (20130101) H01S 5/3054 (20130101) H01S 5/3201 (20130101) H01S 5/18308 (20130101) Original (OR) Class H01S 5/18322 (20130101) H01S 5/18327 (20130101) H01S 5/18358 (20130101) H01S 2301/166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10525101 | Vandenbark et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Arthur A. Vandenbark (Portland, Oregon); Gil Benedek (Portland, Oregon); Roberto Meza-Romero (Beaverton, Oregon) |
| ABSTRACT | Recombinant polypeptides, pharmaceutical compositions comprising recombinant polypeptides, and methods of treating autoimmune and/or inflammatory diseases using the pharmaceutical compositions are disclosed. The polypeptides are based upon the trimerization and/or MIF binding domains of CD74. |
| FILED | Friday, October 21, 2016 |
| APPL NO | 15/331612 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1774 (20130101) Original (OR) Class Peptides C07K 14/70539 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527544 | Titus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Jitto Titus (Acworth, Georgia); Emilie Viennois (Atlanta, Georgia); A. G. Unil Perera (Mableton, Georgia); Merlin Didier (Decatur, Georgia) |
| ABSTRACT | Disclosed are methods, systems, and apparatuses for non-invasive detection of colitis in a subject. The methods involve depositing a bodily fluid sample from the subject on an internal reflection element (IRE). A beam of infrared (IR) radiation can then be directed through the IRE under conditions such that the IR radiation interacts with the bodily fluid sample. An absorption spectrum can then be recorded over a range of preselected frequencies to detect peaks that are affected by colitis. In preferred embodiments, the methods and systems involve Fourier Transform Infrared Spectroscopy (FTIR). |
| FILED | Monday, June 13, 2016 |
| APPL NO | 15/735661 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4255 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/552 (20130101) Original (OR) Class G01N 21/3581 (20130101) G01N 2021/3595 (20130101) G01N 2800/067 (20130101) G01N 2800/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10527577 | Jothimuthu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); The United States of America as represented by the Department of Veteran Affairs (Washington DC) (Washington, District of Columbia) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The United States of America as represented by the Department of Veteran Affairs (Washington DC) (Washington, District of Columbia) |
| INVENTOR(S) | Preetha Jothimuthu (Santa Clara, California); Mohammed Inayathullah Nazir Ahmed (Santa Clara, California); Wen A. Tian (Redwood City, California); Jayakumar Rajadas (Cupertino, California); Mark Nicolls (Palo Alto, California); JooChuan Ang (Berkeley, California) |
| ABSTRACT | Improved electrochemical impedance spectroscopy assays are provided by electrodepositing metallic nanoparticles onto the working electrode for electrochemical impedance spectroscopy. The metallic nanoparticles provide improved assay sensitivity. Electrodeposition of the metallic nanoparticles firmly affixes them to the working electrode, thereby making it easier to clean the working electrode from one assay to the next assay without undesirably removing the metallic nanoparticles. |
| FILED | Tuesday, July 18, 2017 |
| APPL NO | 15/653336 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/31 (20130101) C23C 18/1824 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 5/02 (20130101) C25D 13/02 (20130101) C25D 13/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3278 (20130101) Original (OR) Class G01N 27/4145 (20130101) G01N 27/4146 (20130101) G01N 33/53 (20130101) G01N 33/5438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 10526633 | Ramasamy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| INVENTOR(S) | Ramaraja P. Ramasamy (Watkinsville, Georgia); Yi Fang (Athens, Georgia) |
| ABSTRACT | Provided herein are plant/plant pathogen volatile compound electrochemical sensors, plant/plant pathogen volatile detection systems, and methods for detecting stress-induced plant volatile compounds and/or a plant-pathogen emitted volatile compounds. |
| FILED | Friday, April 15, 2016 |
| APPL NO | 15/566438 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/005 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3277 (20130101) G01N 27/3278 (20130101) G01N 33/025 (20130101) G01N 33/0047 (20130101) G01N 33/0098 (20130101) G01N 33/483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10526649 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Fei Chen (Cambridge, Massachusetts); Shahar Alon (Cambridge, Massachusetts); Andrew Payne (Cambridge, Massachusetts); Asmamaw Wassie (Boston, Massachusetts); Daniel Goodwin (Somerville, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Evan Daugharthy (Cambridge, Massachusetts); Jonathan Scheiman (New York, New York) |
| ABSTRACT | The invention provides in situ nucleic acid sequencing to be conducted in biological specimens that have been physically expanded. The invention leverages the techniques for expansion microscopy (ExM) to provide new methods for in situ sequencing of nucleic acids in a process referred to herein as “expansion sequencing” (ExSEQ). |
| FILED | Friday, October 20, 2017 |
| APPL NO | 15/789419 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) C12Q 1/6841 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2545/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529975 | Song et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | West Virginia University (Morgantown, West Virginia) |
| ASSIGNEE(S) | West Virginia University (Morgantown, West Virginia) |
| INVENTOR(S) | Xueyan Song (Morgantown, West Virginia); Yun Chen (Morgantown, West Virginia); Kirk Gerdes (Morgantown, West Virginia); Shiwoo Lee (Morgantown, West Virginia) |
| ABSTRACT | One embodiment includes forming surface-modifying phases on a surface of a functional electrode via atomic layer deposition and controlling the chemistry of constituent phases, the crystalline nature of the constituent phases and the thickness of the surface-modifying phase via the atomic layer deposition such that the thickness is between about 2 nm to about 200 nm. The surface-modifying phases enhances the performance of electrocatalytic activity of the functional electrode and the device. |
| FILED | Friday, July 31, 2015 |
| APPL NO | 14/814881 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0428 (20130101) Original (OR) Class H01M 4/8626 (20130101) H01M 4/8878 (20130101) H01M 8/1213 (20130101) H01M 8/1246 (20130101) H01M 2008/1293 (20130101) H01M 2300/0074 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/525 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/56 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 10529418 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Miao Hu (Palo Alto, California); John Paul Strachan (Palo Alto, California); Zhiyong Li (Foster City, California); R. Stanley Williams (Portola Valley, California) |
| ABSTRACT | Examples herein relate to linear transformation accelerators. An example linear transformation accelerator may include a crossbar array programmed to calculate a linear transformation. The crossbar array has a plurality of words lines, a plurality of bit lines, and a memory cell coupled between each unique combination of one word line and one bit line, where the memory cells are programmed according to a linear transformation matrix. The plurality of word lines are to receive an input vector, and the plurality of bit lines are to output an output vector representing a linear transformation of the input vector. |
| FILED | Friday, February 19, 2016 |
| APPL NO | 16/079998 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/56 (20130101) G11C 13/0026 (20130101) G11C 13/0028 (20130101) Original (OR) Class G11C 2213/77 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10529909 | Dial et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Oliver Dial (Yorktown Heights, New York); Jay M. Gambetta (Yorktown Heights, New York); Douglas T. McClure, III (Rye, New York); Matthias Steffen (Cortlandt Manor, New York) |
| ABSTRACT | A technique relates a superconducting microwave cavity. An array of posts has different heights in the cavity, and the array supports a localized microwave mode. The array of posts includes lower resonant frequency posts and higher resonant frequency posts. The higher resonant frequency posts are arranged around the lower resonant frequency posts. A first plate is opposite a second plate in the cavity. One end of the lower resonant frequency posts is positioned on the second plate so as to be electrically connected to the second plate. Another end of the lower resonant frequency posts in the array is open so as not to form an electrical connection to the first plate. Qubits are connected to the lower resonant frequency posts in the array of posts, such that each of the qubits is physically connected to one or two of the lower resonant frequency posts in the array of posts. |
| FILED | Wednesday, April 04, 2018 |
| APPL NO | 15/945281 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) G06N 20/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/14 (20130101) H01L 39/24 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10530068 | Mirmozafari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Mirhamed Mirmozafari (Norman, Oklahoma); Guifu Zhang (Norman, Oklahoma) |
| ABSTRACT | A dual linear polarized dipole antenna (and arrays of such antennas) having high isolation between ports. The antenna may include a pair of crossed (collocated) bent (angled) dipole antenna elements which are excited by a unique dual-polarized feeding structure. The antenna elements may be printed. Stripline feeding along with substantially symmetrical and substantially identical radiative (e.g., “radiating”) elements results in high level of port isolation. Sub-ground planes may be positioned about the stripline on both sides of a balun block to limit or reduce parasitic stripline radiation, thereby improving polarization purity. Polarization purity may be additionally reinforced by a principal ground plane which isolates the radiative elements from the baluns. The antennas and antenna arrays may be used, for example, for weather observation and air surveillance. |
| FILED | Wednesday, July 18, 2018 |
| APPL NO | 16/039102 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 5/48 (20150115) H01Q 9/0478 (20130101) H01Q 21/26 (20130101) H01Q 25/001 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10530488 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Cheng Li (Palo Alto, California); Di Liang (Santa Barbara, California); Kehan Zhu (Palo Alto, California) |
| ABSTRACT | Examples disclosed herein relate to optical driver circuits. In some of the disclosed examples, an optical driver circuit includes a pre-driver circuit and a main driver circuit. The pre-driver circuit may include a pattern generator and at least one serializer to generate a main modulation signal and an inverted delayed modulation signal. The main driver circuit may include a level controller to control amplitudes of pre-emphasis on rising and falling edges of a modulation signal output and an equalization controller to transition the modulation signal output from the pre-emphasis amplitudes to main modulation amplitudes using the inverted delayed modulation signal. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/231159 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/58 (20130101) H04B 10/504 (20130101) H04B 10/541 (20130101) H04B 10/564 (20130101) Original (OR) Class H04B 10/801 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/028 (20130101) H04L 25/03885 (20130101) H04L 27/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10528600 | Ni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Kang-Yu Ni (Calabasas, California); Tsai-Ching Lu (Thousand Oaks, California); Qin Jiang (Oak Park, California); David J. Huber (Calabasas, California) |
| ABSTRACT | Described is a system for identifying communication behavior patterns in communication activity time series. For each pair of variables in the communication activity time series, the system determines a transfer entropy measure, an effective transfer entropy measure from a randomly reordered version of the communication activity time series, and a partial effective transfer entropy measure. A dependency matrix is generated using pair-wised effective transfer entropy measures and partial effective transfer entropy measures, where each element in the matrix represents a total influence of a communication activity time series on another communication activity time series in the future. The dependency matrix is compared with dependency matrices generated from a predefined set of communication patterns to identify the communication behavior pattern. The system generates instructions regarding positioning of a sensor, such that the instructions provide guidance regarding placement of the sensor at a geographical region related to the identified communication pattern. |
| FILED | Thursday, July 12, 2018 |
| APPL NO | 16/034139 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Electric Digital Data Processing G06F 16/285 (20190101) Original (OR) Class G06F 16/2228 (20190101) Wireless Communication Networks H04W 16/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
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THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, January 07, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
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APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
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The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200107.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page