FedInvent™ Patents
Patent Details for Tuesday, January 21, 2020
This page was updated on Monday, March 27, 2023 at 06:00 AM GMT
Department of Defense (DOD)
| US 10537275 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Quan Zhang (Winchester, Massachusetts); Gary Strangman (Boxford, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Quan Zhang (Winchester, Massachusetts); Gary Strangman (Boxford, Massachusetts) |
| ABSTRACT | A system and a method is provided for assessing motion of a biological tissue of a subject including one or more superficial biological layers and a targeted biological layer. An optical perturbation is introduced within the one or more superficial biological layers but not within the targeted biological layer. A set of optical signal data is acquired preceding, during, or following the optical perturbation and, using the set of optical signal data, a set of optical characteristics is determined that is representative of light transiting the biological layers. Using the set of optical characteristics and a model of the biological layers, a target optical signal consistent with a target biological layer is separated and a movement of the desired biological tissue is determined using the target optical signal. |
| FILED | Wednesday, June 25, 2014 |
| APPL NO | 14/900840 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/4064 (20130101) Original (OR) Class A61B 5/6814 (20130101) A61B 5/14553 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537337 | Gordon et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); The United States of America; As represented by the Secretary of Defence, Walter Reed National Military Medical Center (Washington, District of Columbia); The United States of America; as Represented by the Secretary of the Navy, IP Counsel of the Navy Office of Naval Research (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chad Gordon (Lutherville, Maryland); Mehran Armand (Fulton, Maryland); Ryan Murphy (Columbia, Maryland); Gerald Grant (Goshen, Kentucky); Peter Liacouras (North Potomac, Maryland); Kevin Wolfe (Lutherville, Maryland) |
| ABSTRACT | A computer-assisted surgical system can include a donor sub-system and a recipient sub-system. The donor sub-system includes a first reference unit having a first trackable element, a fragment reference unit having a second trackable element, and a first detector configured to provide at least one of a first signal corresponding to a detected location of one or more of the first trackable element and the second trackable element. The recipient sub-system includes a second reference unit having a third trackable element, and a second detector configured to provide at least one of a second signal corresponding to a detected location of at least the third trackable element. |
| FILED | Tuesday, November 25, 2014 |
| APPL NO | 15/100258 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/15 (20130101) Original (OR) Class A61B 17/176 (20130101) A61B 17/1695 (20130101) A61B 17/1739 (20130101) A61B 17/8085 (20130101) A61B 34/10 (20160201) A61B 34/20 (20160201) A61B 2034/105 (20160201) A61B 2034/108 (20160201) A61B 2034/2051 (20160201) A61B 2034/2055 (20160201) A61B 2034/2065 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2803 (20130101) Electric Digital Data Processing G06F 19/3481 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537689 | Yoo et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wake Forest University Health Sciences (Wiston-Salem, North Carolina) |
| ASSIGNEE(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| INVENTOR(S) | James J. Yoo (Winston-Salem, North Carolina); Anthony Atala (Winston-Salem, North Carolina); Kyle W. Binder (Winston-Salem, North Carolina); Mohammad Z. Albanna (Winston-Salem, North Carolina); Weixin Zhao (Winston-Salem, North Carolina); Dennis Dice (Yadkinville, North Carolina); Tao Xu (El Paso, Texas) |
| ABSTRACT | Provided herein is a delivery system, including: (a) an optical sensor configured to detect data to create a map of a patient bodily surface; and (b) a dispenser operatively associated with the optical sensor and configured to deliver compositions (optionally including cells) to the patient bodily surface based upon the data or map. Methods of forming a tissue on a patient bodily surface of a patient in need thereof are also provided, as are methods, systems and computer program products useful for processing patient bodily surface data. |
| FILED | Friday, October 12, 2018 |
| APPL NO | 16/158808 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0064 (20130101) A61B 5/445 (20130101) A61B 5/1077 (20130101) A61B 5/1079 (20130101) A61B 5/6835 (20130101) A61B 34/30 (20160201) A61B 90/50 (20160201) A61B 2017/00969 (20130101) A61B 2017/3225 (20130101) A61B 2034/105 (20160201) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/60 (20130101) A61L 27/225 (20130101) A61L 27/3813 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/00 (20130101) Original (OR) Class A61M 35/00 (20130101) Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 3/4073 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0656 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537733 | Dixon et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Warren Dixon (Gainesville, Florida); Matthew J. Bellman (Gainesville, Florida) |
| ABSTRACT | Functional electrical stimulation (FES) cycling devices and associated methods are generally described. An FES cycling device may comprise a crank, two or more pedals connected to the crank, one or more sensors adapted to measure position and/or velocity of the crank, and one or more electrodes configured to deliver electrical stimulation to a person associated with the cycling device. In some cases, the FES cycling device further comprises a controller configured to receive input signals from the one or more sensors and deliver output signals to the one or more electrodes. In certain cases, the controller may dynamically generate a control signal to deliver an amount of electrical stimulation to a muscle group (e.g., quadriceps femoris, gluteal muscles, hamstring muscles) based on the value of a determined torque transfer ratio between a joint of the person and the crank of the cycling device. The electrical stimulation may, in some cases, cause the person to pedal the cycling device. |
| FILED | Friday, June 05, 2015 |
| APPL NO | 15/308541 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0452 (20130101) A61N 1/0484 (20130101) A61N 1/36003 (20130101) Original (OR) Class A61N 1/36014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537854 | Pozzo et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Lilo D. Pozzo (Seattle, Washington); Anthony William Moretti (Seattle, Washington); Gregory M. Newbloom (Seattle, Washington); Aaron West (Seattle, Washington); Eden Rivers (Seattle, Washington) |
| ABSTRACT | Disclosed herein are ceramic selective membranes and methods of forming the ceramic selective membranes by forming a selective silica ceramic on a porous membrane substrate. Representative ceramic selective membranes include ion-conductive membranes (e.g., proton-conducting membranes) and gas selective membranes. Representative uses for the membranes include incorporation into fuel cells and redox flow batteries (RFB) as ion-conducting membranes. |
| FILED | Friday, October 27, 2017 |
| APPL NO | 15/796607 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Separation B01D 39/2068 (20130101) B01D 53/228 (20130101) B01D 61/025 (20130101) B01D 67/0048 (20130101) Original (OR) Class B01D 67/0076 (20130101) B01D 67/0079 (20130101) B01D 67/0088 (20130101) B01D 69/12 (20130101) B01D 69/105 (20130101) B01D 71/02 (20130101) B01D 71/26 (20130101) B01D 71/027 (20130101) B01D 71/28 (20130101) B01D 71/76 (20130101) B01D 2256/16 (20130101) B01D 2257/102 (20130101) B01D 2257/504 (20130101) B01D 2323/286 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) H01M 8/0236 (20130101) H01M 8/0239 (20130101) H01M 8/0245 (20130101) H01M 8/1016 (20130101) H01M 8/1053 (20130101) H01M 8/1062 (20130101) H01M 2300/0094 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537998 | Salisbury et al. |
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| FUNDED BY |
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| APPLICANT(S) | SRI INTERNATIONAL (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Curt Salisbury (San Ramon, California); Mike Stevens (Menlo Park, California); Zachery Shivers (San Francisco, California) |
| ABSTRACT | A compact lightweight robotic end-effector has a large range of possible applied force. The end-effector includes one or more underactuated appendages, where each appendage is driven by a single motor connected to a driving cable wound throughout the appendage. The driving cable may be a flat cable or a cable with another non-circular cross section. The driving cable may be wrapped through a series of pulleys and/or bearings within the appendage to reduce frictional losses. The design of the pulley path may allow a desired mechanical response by the appendage, and the mechanical response may be optimized for a grasping process. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 15/990388 |
| ART UNIT | 3652 — Material and Article Handling |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 13/085 (20130101) Original (OR) Class B25J 15/0009 (20130101) B25J 15/0233 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538191 | Hooper et al. |
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| FUNDED BY |
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| APPLICANT(S) | United States Government (San Diego, California) |
| ASSIGNEE(S) | United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ralph David Hooper (Lemon Grove, California); William A. Chambers (Jamul, California) |
| ABSTRACT | An apparatus for removing and/or installing a side guide of a trailer-mounted boat capture system for guiding a boat onto the trailer, the apparatus comprising: an outboard post pivotally attached to an upper support rail of the side guide; two inboard posts, each pivotally attached to the side guide proximal to where the side guide is attached to the trailer via first pins, wherein each inboard post includes a manual leveling jack; an attachment point on the side guide suitable for attaching a winch cable from a boat held in the boat capture system; and second pins attaching the side guide to the trailer such that when the first pins are removed the side guide is free to pivot around the second pins from an upright position towards a support surface. |
| FILED | Thursday, December 21, 2017 |
| APPL NO | 15/851056 |
| ART UNIT | 3611 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Buttons, Pins, Buckles, Slide Fasteners, or the Like A44B 13/02 (20130101) Vehicles Adapted for Load Transportation or to Transport, to Carry, or to Comprise Special Loads or Objects B60P 3/10 (20130101) B60P 3/1075 (20130101) Original (OR) Class Hand-propelled Vehicles, e.g Hand Carts or Perambulators; Sledges B62B 3/02 (20130101) B62B 3/04 (20130101) B62B 5/067 (20130101) B62B 5/0438 (20130101) B62B 2005/0471 (20130101) B62B 2202/90 (20130101) B62B 2301/04 (20130101) Ships or Other Waterborne Vessels; Equipment for Shipping B63B 21/54 (20130101) B63B 21/60 (20130101) B63B 2027/165 (20130101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 2008/002 (20130101) Cranes; Load-engaging Elements or Devices for Cranes, Capstans, Winches, or Tackles B66C 1/36 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 45/02 (20130101) F16B 45/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538322 | Alber et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Mark R. Alber (Milford, Connecticut); Charles Gayagoy (Orange, Connecticut) |
| ABSTRACT | A vertical take-off and landing (VTOL) aircraft is provided. The aircraft includes a wing, nacelles supportively disposed at opposite ends of the wing, proprotors respectively attached to each of the nacelles with each of the proprotors being rotatable to generate lift in vertical flight and thrust in horizontal flight and a delta-wing shaped fuselage disposed along the wing between the nacelles. |
| FILED | Friday, October 16, 2015 |
| APPL NO | 15/533505 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/0009 (20130101) B64C 7/02 (20130101) B64C 23/069 (20170501) B64C 29/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538331 | Taylor et al. |
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| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Bill K. Taylor (Tucson, Arizona); Keith A. Kerns (Tucson, Arizona); Michael S. Grygla (Tucson, Arizona) |
| ABSTRACT | A fastening system with a rotatable fastener that may secure an aircraft store to an aircraft and may rotate to reduce a drag coefficient of the aircraft store. Reducing the drag coefficient of the aircraft store may increase fuel efficiency of the aircraft store by requiring less energy to propel the aircraft store at a given speed or acceleration. The rotatable fastener allows the aircraft store to attach to the aircraft and to possess a low drag coefficient once the aircraft store is deployed. The rotatable fastener member may be configured to conform to attachment interface standards, such as Standardization Agreement (“STANAG”) 3842 or any other suitable aircraft store attachment interface standard. |
| FILED | Friday, January 08, 2016 |
| APPL NO | 14/991347 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/04 (20130101) Original (OR) Class Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 2/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538494 | Blanski et al. |
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| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
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| INVENTOR(S) | Rusty L. Blanski (Palmdale, California); Robert H. Grubbs (South Pasadena, California) |
| ABSTRACT | Backfunctionalized imidazolinium salts and methods of synthesizing the same and NHC carbene-metal complexes therefrom. For backfunctionalized imidazolinium salts of the formula: Wherein R1 is selected from the group consisting of an ester group, an amide group, and an aromatic group; R2 is selected from the group consisting of hydrogen, an ester group, an amide group, and an aromatic group; R3 and R4 are each selected from the group consisting of a C1-C20 alkyl group, C1-C20 partially fluorinated alkyl group, an aryl group, an aryl group with para CF3 functionality, an aryl group having C1-C20 partially fluorinated alkyl groups or partially fluorinated alkoxy groups, and a C1-C20 partially fluorinated aliphatic group, and a C1-C20 aryl group; and X is an anion. The method comprises cyclization of a halogenated acrylate with a formamidine with Hünig's base in a solvent. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/103267 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 233/28 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0033 (20130101) C07F 15/0046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538588 | Adusumilli et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); The U.S.A. as Represented by the Secretary, Department Of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); THE U.S.A. AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Prasad S. Adusumilli (New York, New York); Michel Sadelain (New York, New York); Dimiter S. Dimitrov (Frederick, Maryland); Yang Feng (Frederick, Maryland) |
| ABSTRACT | The presently disclosed subject matter provides for methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to chimeric antigen receptors (CARs) that specifically target human mesothelin, and immunoresponsive cells comprising such CARs. The presently disclosed mesothelin-targeted CARs have enhanced immune-activating properties, including anti-tumor activity. |
| FILED | Wednesday, May 16, 2018 |
| APPL NO | 15/981142 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/705 (20130101) C07K 14/4748 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 2317/21 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538713 | Willigan |
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| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Rhonda R. Willigan (Manchester, Connecticut) |
| ABSTRACT | Disclosed herein is a fuel blend comprising a hydrocarbon based fuel; and particles that comprise magnesium and boron. Disclosed herein too is a method comprising blending a composition comprising a hydrocarbon based fuel and particles that comprise magnesium and boron to form a fuel blend. |
| FILED | Friday, May 19, 2017 |
| APPL NO | 15/600012 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) Original (OR) Class C10L 1/12 (20130101) C10L 1/1208 (20130101) C10L 1/1216 (20130101) C10L 1/1233 (20130101) C10L 2200/0213 (20130101) C10L 2200/0254 (20130101) C10L 2270/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538749 | Harvey et al. |
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| FUNDED BY |
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| APPLICANT(S) | U.S. Army Edgewood Chemical Biological Center (APG, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Steven P Harvey (Lutherville, Maryland); Melissa M Dixon (Abingdon, Maryland); Mark A Guelta (White Marsh, Maryland) |
| ABSTRACT | The invention comprises isolated, mutant, non-wild-type organophosphorus acid anhydrolase (OPAA) enzymes having two site mutations, methods of production, and methods of use to effectively degrade cylcosarin (GF) (cyclohexyl methylphosphonofluoridate) with greater catalytic efficiency than the wild-type OPAA. |
| FILED | Friday, January 19, 2018 |
| APPL NO | 15/875071 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/08002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538756 | Brangwynne et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Cliff Brangwynne (Hopewell, New Jersey); Dan Bracha (Princeton, New Jersey) |
| ABSTRACT | A system and method for reversibly controlling clustering of proteins around an engineered multivalent nucleus is disclosed. The system and method utilize clustering, which may be controlled by light activation or deactivation. The system and method enable the spatiotemporal control of protein supramolecular assemblies, including liquid-like droplets under some conditions, and solid-like gels under other conditions. The system and method can be utilized for segregating or locally concentrating desired proteins and/or RNA in cells or cell lysate, which may be useful for protein purification purposes, or for assembling single or multiple membraneless bodies within specific sub-regions of the cells. These synthetically assembled bodies may recruit both transgenic and endogenic proteins and other biomolecules, thus can be linked to affect and even trigger a plethora of cellular processes, including both physiological and pathological (e.g., protein aggregation) processes. |
| FILED | Friday, June 09, 2017 |
| APPL NO | 15/618361 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/00 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538807 | Bielas et al. |
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| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Jason H. Bielas (Seattle, Washington); Sean D. Taylor (Kirkland, Washington); Matthew T. Laurie (Olympia, Washington) |
| ABSTRACT | The present disclosure relates to compositions and methods for detecting rare nucleic acid molecule mutations in a plurality of nucleic acid molecules. Also disclosed are methods for determining the size of a nucleic acid molecule using droplet digital PCR. |
| FILED | Wednesday, May 29, 2013 |
| APPL NO | 14/402820 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538861 | Shah et al. |
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| FUNDED BY |
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| APPLICANT(S) | Radiation Monitoring Devices, Inc. (Watertown, Massachusetts) |
| ASSIGNEE(S) | Radiation Monitoring Devices, Inc. (Watertown, Massachusetts) |
| INVENTOR(S) | Kanai S. Shah (Watertown, Massachusetts); Josh Tower (Natick, Massachusetts); Rastgo Hawrami (Watertown, Massachusetts) |
| ABSTRACT | Disclosed embodiments are related to a method of forming an elpasolite scintillator. In one nonlimiting embodiment, a method of forming an elpasolite scinitillator may comprise forming an elpasolite crystal from a nonstoichiometric melt. |
| FILED | Thursday, January 29, 2015 |
| APPL NO | 14/608665 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/77 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 11/02 (20130101) C30B 13/16 (20130101) C30B 15/00 (20130101) C30B 29/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539030 | Kastel |
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| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Donald Kastel (Hamden, Connecticut) |
| ABSTRACT | A stator vane for a gas turbine engine includes a first platform and a second platform radially spaced apart from one another. The first and second airfoils are circumferentially spaced from one another and interconnect the first and second platforms. The first platform has a gas path side facing the airfoils and a non-gas path side opposite the gas path side. A circumferentially extending rail provided on the first platform extends radially outward from the gas path side to the non-gas path side to form a pocket on the non-gas path side between the first platform and the rail. A reinforcement is arranged in the pocket and joins the first platform and the rail. The reinforcement includes a variable thickness in the circumferential direction and is arranged generally centrally between the first and second airfoils. |
| FILED | Monday, February 24, 2014 |
| APPL NO | 14/767478 |
| ART UNIT | 3748 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/04 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539076 | Niergarth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Daniel Alan Niergarth (Cincinnati, Ohio); Brandon Wayne Miller (Middletown, Ohio); Kyle Robert Snow (Loveland, Ohio); Christopher James Kroger (West Chester, Ohio) |
| ABSTRACT | A self-contained lubrication fluid circulation system for use with a gas turbine engine defining a core air flowpath includes a sump configured to collect lubrication fluid and a heat source coupled in fluid communication with the sump and configured to transfer heat to the lubrication fluid. The system also includes a heat sink positioned within the sump and coupled in fluid communication with the heat source. A lubrication fluid conduit of the system is configured to channel the lubrication fluid between the heat source and the heat sink, wherein the lubrication fluid conduit is positioned entirely within the sump. |
| FILED | Tuesday, November 10, 2015 |
| APPL NO | 14/937266 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/02 (20130101) F01D 25/20 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/14 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/98 (20130101) Lubricating F16N 9/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539270 | Diviacchi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Edgewood Chemical Biological Center (APG, Maryland) |
| ASSIGNEE(S) | America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Giancarlo Diviacchi (Baltimore, Maryland) |
| ABSTRACT | A mixture and method of creating the mixture includes mixing hexachloroethane, stannous oxide, and aluminum together. The mixture may be loaded into at least one canister. The mixture may be combusted to create a smoke screen. The loading of the mixture into the at least one canister may include pressurized loading at loading pressures in the range of approximately 2300 psi to 3600 psi. The hexachloroethane may include approximately 30-40 parts by weight of the mixture and have a particle size of approximately less than 850 μm. The stannous oxide may include approximately 55-65 parts by weight of the mixture and have a particle size of approximately less than 150 μm. The aluminum may include approximately 5-10 parts by weight of the mixture and have a particle size of approximately less than 45 μm. The mixture is devoid of zinc chloride. |
| FILED | Wednesday, November 14, 2018 |
| APPL NO | 16/191039 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Means for Generating Smoke or Mist; Gas-attack Compositions; Generation of Gas for Blasting or Propulsion C06D 3/00 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 5/00 (20130101) Original (OR) Class F17C 2221/03 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 9/06 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539320 | Bottiger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Edgewood Chemical and Biological Command (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jerold R. Bottiger (Aberdeen, Maryland); Jana S. Kesavan (Catonsville, Maryland); Deborah R. Schepers (Bel Air, Maryland) |
| ABSTRACT | A system and method for generating combustion aerosols from liquid fuel. The system includes a furnace with an inner heating tube having a heating tape wrapped thereabout. Further, the system includes a fuel line extending through an inlet end of the heating tube and into the heating tube, and a means for dripping the liquid fuel onto a plurality of different locations on an inner surface of the heating tube. The system further includes a power supply to power the heating tape to heat the inner heating tube to a temperature which can ignite the liquid fuel dripped onto the inner surface of the inner heating tube whereby there is an immediate combustion to form combustion products. Finally, the system includes an air line connected to the heating tube for directing compressed air through the inner heating tube to mix with the combustion products and transport the formed combustion aerosols out of an outlet end of the inner heating tube. |
| FILED | Tuesday, August 25, 2015 |
| APPL NO | 14/835199 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Methods of Steam Generation; Steam Boilers F22B 1/288 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539346 | Coppola et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Anthony Coppola (Urbana, Illinois); Scott R. White (Champaign, Illinois); Nancy R. Sottos (Champaign, Illinois) |
| ABSTRACT | Autonomic cooling of a substrate is achieved using a porous thermal protective layer to provide evaporative cooling combined with capillary pumping. The porous thermal protective layer is manufactured onto the substrate. A vascular network is integrated between the substrate and the protective layer. Applied heat causes fluid contained in the protective layer to evaporate, removing heat. The fluid lost to evaporation is replaced by capillary pressure, pulling fluid from a fluid-containing reservoir through the vascular network. Cooling occurs as liquid evaporates from the protective layer. |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/274591 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 7/004 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/024 (20130101) B32B 5/26 (20130101) B32B 7/12 (20130101) B32B 9/005 (20130101) B32B 9/041 (20130101) B32B 9/045 (20130101) B32B 9/047 (20130101) B32B 15/00 (20130101) B32B 15/01 (20130101) B32B 15/08 (20130101) B32B 15/14 (20130101) B32B 15/18 (20130101) B32B 15/20 (20130101) B32B 18/00 (20130101) B32B 27/06 (20130101) B32B 27/08 (20130101) B32B 27/12 (20130101) B32B 2250/02 (20130101) B32B 2260/023 (20130101) B32B 2260/046 (20130101) B32B 2262/101 (20130101) B32B 2262/106 (20130101) B32B 2307/50 (20130101) B32B 2307/306 (20130101) B32B 2307/732 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 19/00 (20130101) Original (OR) Class Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539393 | Surdu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cole Engineering Services, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | Cole Engineering Services, Inc. (Orlando, Florida) |
| INVENTOR(S) | John Surdu (Severn, Maryland); Josh Crow (Orlando, Florida); Chris Ferrer (Orlando, Florida); Rick Noriega (Longwood, Florida); Peggy Hughley (Winter Springs, Florida); Padraic Baker (Orlando, Florida) |
| ABSTRACT | A shooting simulation system and method for training personnel in targeting visual and non-line-of-sight targets. The firearm simulation system has a plurality of participants each having a firearm and each being equipped to transmit their location to a remote computer server for storage and use with other transmitted data to determine which participant was a Shooter and which participant was the Shooter's target and for determining a simulated hit or miss of the target and assessing the simulated damage to the target. |
| FILED | Monday, April 22, 2019 |
| APPL NO | 16/390189 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 33/00 (20130101) Weapon Sights; Aiming F41G 3/2605 (20130101) Original (OR) Class Targets; Target Ranges; Bullet Catchers F41J 5/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539404 | Lustig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Edward A. Lustig (Charlotte Hall, Maryland); Eric Gahagan (Winthrop, Massachusetts); John W. Monico, Jr. (Stafford, Virginia); Paul C. Perricone (New York City, New York); William Qualls (Plymouth, Massachusetts); Michael Agens (Columbia, New Jersey); Daniel C. Jones (Stow, Massachusetts); John Winslow (Falls Church, Virginia); Michael Murray (Worcester, Massachusetts); Kimberly Peranich, Sr. (White Plains, Maryland); Lee Foltz (Indian Head, Maryland); Jesse Stuart Moran (Alexandria, Virginia); Christopher Wilhelm (Port Tobacco, Maryland); Lesley Wilhelm (Port Tobacco, Maryland); John Wilkinson (Charlotte Hall, Maryland) |
| ABSTRACT | A blast containment system for trash cans includes a liquid-impervious flexible bag having a sealed bottom positioned at a base of a trash can, and an unsealed top positioned and retained at a top periphery of the trash can. A ring-shaped boot is positioned at the sealed bottom of the flexible bag. A rigid container has a closed bottom press-fit into a central opening of the boot. The rigid container extends from its closed bottom to an open top adapted to be approximately aligned with the top periphery of the trash can. An annular volume is defined between the rigid container the flexible bag. The rigid container has side walls that include ballistic materials. A liquid fills the annular volume. |
| FILED | Friday, March 23, 2018 |
| APPL NO | 15/932602 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Gathering or Removal of Domestic or Like Refuse B65F 1/02 (20130101) Blasting F42D 5/045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539419 | Stanley-Marbell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Phillip Stanley-Marbell (Boston, Massachusetts); Martin C. Rinard (Arlington, Massachusetts) |
| ABSTRACT | A sensor produces the sensor data for a sensor data consumer. A facility receives a sensor profile of the sensor indicating a relationship between a sensor parameter operating range and a deviation of the sensor data as a result of scaling one or more sensor parameters. The facility receives a tolerance profile of the sensor data consumer indicating a tolerable degree of deviation of the sensor data and scales a parameter of the sensor according to the tolerance profile. The scaling reduces a power dissipation level of the sensor. |
| FILED | Tuesday, May 16, 2017 |
| APPL NO | 15/596568 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/10 (20130101) Original (OR) Class Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539508 | Suslick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Kenneth S. Suslick (Champaign, Illinois); Jon R. Askim (Urbana, Illinois) |
| ABSTRACT | A portable device for colorimetric or fluorometric analysis comprises a linear array of optically-responsive chemical sensing elements; an image sensor in optical communication with the linear array for determining a spectral response of the optically-responsive chemical sensing elements, where the image sensor comprises at least one light emission source; and electronics connected to the image sensor for analyzing spectral response data. A method of conducting colorimetric or fluorometric analysis comprises exposing a linear array of optically-responsive chemical sensing elements to a fluid comprising an analyte; impinging light on the linear array and detecting a spectral response of the chemical sensing elements; and determining an exposed color of each of the chemical sensing elements. |
| FILED | Tuesday, June 09, 2015 |
| APPL NO | 15/317840 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Original (OR) Class G01N 21/80 (20130101) G01N 2021/7773 (20130101) G01N 2021/7786 (20130101) G01N 2021/7793 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539655 | Hernandez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Arlingtion, Virginia) |
| INVENTOR(S) | John Christopher Hernandez (El Paso, Texas); Dustin Wayne Morris (Poulsbo, Washington) |
| ABSTRACT | A computer-implemented method of identifying a target includes receiving at least one data input related to the target from at least one data source. At least one acoustic parameter is calculated from the at least one data input. A target identification algorithm is applied to at least one acoustic data parameter. An identification of the target is produced from at least one acoustic parameter when the target identification algorithm is applied thereto. The identification of the target is displayed. |
| FILED | Friday, March 30, 2018 |
| APPL NO | 15/941536 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540442 | Beller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles E. Beller (Baltimore, Maryland); Paul J. Chase, Jr. (Fairfax, Virginia); Richard L. Darden (Leesburg, Virginia); Edward G. Katz (Washington, District of Columbia) |
| ABSTRACT | Mechanisms are provided for evaluating a temporal relevance of a candidate answer to an input natural language question. An input natural language question is received and analyzed to identify a temporal focus of the input natural language question. A corpus of documents is processed based on the input natural language question to generate candidate answers to the input natural language question, where each candidate answer is processed to identify at least one contextual temporal focus associated with the candidate answer. The at least one contextual temporal focus is compared with the temporal focus of the input natural language question and a measure of temporal relevance of the candidate answer based on results of the comparison is generated. A final answer to the input natural language question is output based on the measure of temporal relevance. |
| FILED | Wednesday, July 20, 2016 |
| APPL NO | 15/214529 |
| ART UNIT | 2168 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 17/277 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540459 | McKennon-Kelly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Ryan Edward George McKennon-Kelly (Springfield, Virginia); Felix R Hoots, Jr. (Colorado Springs, Colorado); Brian Whitelaw Hansen (Fairfax, Virginia); David Yengle Stodden (Hawthorne, California) |
| ABSTRACT | A computer-implemented method for generating a 3-dimensional (3D) model to characterize and visualize debris. The computer-implemented method includes defining a bounding surface for one or more debris fields generated by an on-orbit breakup event. The bounding surface is defined by using an upper limit fragment spreading speed predicted by a breakup model and applying the upper limit fragment spreading speed in different directions to generate points on the bounding surface. The computer-implemented method also includes connecting one or more points on the bounding surface to maintain a single bounded 3D mesh. The computer-implemented method further includes applying color and/or transparency to the 3D model. |
| FILED | Thursday, December 29, 2016 |
| APPL NO | 15/393743 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class G06F 2217/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540502 | Joyce et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Robert A. Joyce (Ithaca, New York); Scott Aloisio (Ithaca, New York); Judson Powers (Ithaca, New York); Christopher Dominessy (Painted Post, New York) |
| ABSTRACT | A risk model for a distributed computing system comprises a plurality of tree nodes organized as a tree. For each tree node of the risk model, the tree node corresponds to a respective event that may befall a distributed computing system. An analysis computing system generates data associating a test agent with a target and also generates data associating the test agent with a tree node in the risk model. The test agent performs a data gathering routine that gathers data from the target associated with the test agent. The gathered data may indicate whether the event corresponding to the tree node is occurring. Furthermore, the analysis computing system may perform the data gathering routine according to a recurrence pattern of the data gathering routine. The analysis computing system may output a graphical representation of the data indicating whether the event corresponding to the tree node is occurring. |
| FILED | Wednesday, June 14, 2017 |
| APPL NO | 15/622434 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2246 (20190101) G06F 21/577 (20130101) Original (OR) Class G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540569 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Yu Cheng (Ossining, New York); Sharathchandra U. Pankanti (Darlen, Connecticut); Nalini K. Ratha (White Plains, New York) |
| ABSTRACT | A face clustering system for video face clustering in a video sequence, the system including an inherent supervision summarization device configured to collect group-level supervision and instance level supervision within a same chunklet based on a user input of face images for a person, a discriminative projection learning device configured to embed group constraints of the group-level supervision into a transformed space, and configured to generate an embedding space from the original image feature space, and a clustering device, in the embedding space, configured to execute pair-wise based clustering to cluster the video images into different clusters with the instance level supervision collected by the inherent supervision summarization device. |
| FILED | Tuesday, October 24, 2017 |
| APPL NO | 15/791801 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00288 (20130101) G06K 9/00295 (20130101) G06K 9/00718 (20130101) G06K 9/6218 (20130101) Original (OR) Class G06K 9/6264 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540571 | Hoover et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADVANCED OPTICAL TECHNOLOGIES, INC. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | ADVANCED OPTICAL TECHNOLOGIES, INC. (Albuquerque, New Mexico) |
| INVENTOR(S) | Brian G. Hoover (Tijeras, New Mexico); Pablo A. Reyes (Albuquerque, New Mexico); David E. Taliaferro (Albuquerque, New Mexico); Virgil N. Kohlhepp, III (Peralta, New Mexico) |
| ABSTRACT | Embodiments of an active or laser polarimeter are disclosed that transmit multiple independent and tunable temporally-multiplexed polarization states and record or image, at video rates if necessary, the polarized intensity or irradiance reflected or transmitted by objects illuminated by those states, and apply the recorded data to material and/or object classification and recognition using classification algorithms that exploit features of polarization signatures dependent on material type, texture, and/or object shape. The polarimeter also generally records and utilizes one or more passive polarization measurements in order to realize a hybrid active-passive polarimeter. The polarimeter channels are configured and tuned to access multi-dimensional signature spaces specified by existing signature models and/or measurements, with polarization-modulator settings derived by a newly-disclosed subspace-projection algorithm that maximizes a target contrast parameter. Multiple independent polarization channels allow the new polarimeter to outperform conventional two-channel polarimeters, while the subspace-projection algorithm allows the number of channels to be minimized in order to minimize sensor size, weight, and power (SWaP) and maximize speed. Multiple channels are realized by multiplexing among independent transmitter polarization states with one or more high-speed multiplexers, in one embodiment a set of fold-mirror assemblies in the transmitter among which the laser beam is switched by one or more galvanometer scanners fitted in one embodiment with a newly-disclosed composite mirror. The method for material and object classification and recognition includes the maximally-biased classifier derived by the subspace-projection algorithm applied to a single target Mueller matrix, and methods to generalize the classifier. |
| FILED | Thursday, December 22, 2016 |
| APPL NO | 15/542064 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) G01J 2004/004 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) Optical Elements, Systems, or Apparatus G02B 5/3083 (20130101) G02B 27/283 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/78 (20130101) G06K 9/6232 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540602 | Heeres et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Reinier Heeres (New Haven, Connecticut); Brian Vlastakis (New Haven, Connecticut); Victor V. Albert (New Haven, Connecticut); Stefan Krastanov (New Haven, Connecticut); Liang Jiang (Guilford, Connecticut); Robert J. Schoelkopf, III (Madison, Connecticut) |
| ABSTRACT | According to some aspects, a method is provided of operating a circuit quantum electrodynamics system that includes a physical qubit dispersively coupled to a quantum mechanical oscillator, the method comprising applying a first electromagnetic pulse to the physical qubit based on a number state of the quantum mechanical oscillator, wherein the first electromagnetic pulse causes a change in state of the quantum mechanical oscillator, and applying, subsequent to application of the first electromagnetic pulse, a second electromagnetic pulse to the quantum mechanical oscillator that coherently adds or removes energy from the quantum mechanical oscillator. |
| FILED | Friday, February 26, 2016 |
| APPL NO | 15/552998 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/1847 (20130101) Pulse Technique H03K 19/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541136 | Mazur et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Eric Mazur (Concord, Massachusetts); Michael J. Aziz (Concord, Massachusetts); Hemant Gandhi (Cambridge, Massachusetts); David Pastor (Cambridge, Massachusetts) |
| ABSTRACT | In one aspect a method of fabricating an n-doped strained germanium (Ge) film is disclosed, which includes depositing a strained Ge film on an underlying substrate, implanting at least one electron-donating dopant in the Ge film, and exposing the implanted Ge film to one or more laser pulses having a pulsewidth in a range of about 1 ns to about 100 ms so as to generate a substantially crystalline strained Ge film. In some embodiments, the pulses can cause melting followed by substantial recrystallization of at least a portion of the implanted Ge film. In some embodiments, the resultant Ge film can have a thickness in a range of about 10 nm to about 1 microns. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 15/825398 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/352 (20151001) B23K 26/0622 (20151001) B23K 26/0643 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/268 (20130101) H01L 21/324 (20130101) H01L 21/02381 (20130101) H01L 21/02395 (20130101) H01L 21/02422 (20130101) H01L 21/02532 (20130101) H01L 21/02686 (20130101) Original (OR) Class H01L 21/26513 (20130101) H01L 21/67115 (20130101) H01L 29/36 (20130101) H01L 29/167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541215 | Limb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Scott J. H. Limb (Palo Alto, California); Gregory L. Whiting (Menlo Parl, California) |
| ABSTRACT | A transient electronic device utilizes a glass-based interposer that is treated using ion-exchange processing to increase its fragility, and includes a trigger device operably mounted on a surface thereof. An integrated circuit (IC) die is then bonded to the interposer, and the interposer is mounted to a package structure where it serves, under normal operating conditions, to operably connect the IC die to the package I/O pins/balls. During a transient event (e.g., when unauthorized tampering is detected), a trigger signal is transmitted to the trigger device, causing the trigger device to generate an initial fracture force that is applied onto the glass-based interposer substrate. The interposer is configured such that the initial fracture force propagates through the glass-based interposer substrate with sufficient energy to both entirely powderize the interposer, and to transfer to the IC die, whereby the IC die also powderizes (i.e., visually disappears). |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 16/385452 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/486 (20130101) H01L 21/4853 (20130101) H01L 21/4864 (20130101) H01L 23/15 (20130101) H01L 23/57 (20130101) H01L 23/573 (20130101) Original (OR) Class H01L 23/576 (20130101) H01L 23/49827 (20130101) H01L 23/49838 (20130101) H01L 23/49894 (20130101) H01L 24/00 (20130101) H01L 24/16 (20130101) H01L 25/0655 (20130101) H01L 2224/16157 (20130101) H01L 2224/16235 (20130101) H01L 2924/15311 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541340 | Najmaei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Sina Najmaei (Laurel, Maryland); Madan Dubey (South River, New Jersey) |
| ABSTRACT | A method for controlling any of a responsivity, response time, and trap characteristics of a two-dimensional (2D) material on a self-assembled monolayers (SAMs) device, the method including modifying a surface of an oxide substrate, in an atomic scale, to create the 2D material, wherein the modifying the surface includes modifying a level of impurities trapped in the surface and a doping level of the surface, and forming charge carrier traps at the surface, wherein a capture rate and an emission rate of the charge carrier is influenced by an exposure to a light signal, and wherein the exposure to the light signal further changes the doping level of the surface. |
| FILED | Monday, July 24, 2017 |
| APPL NO | 15/657291 |
| ART UNIT | 3624 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/032 (20130101) H01L 31/186 (20130101) H01L 31/0352 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541345 | King et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Richard R. King (Thousand Oaks, California); Moran Haddad (Granada Hills, California); Philip T. Chiu (La Crescenta, California); Xingquan Liu (La Crescenta, California); Christopher M. Fetzer (Valencia, California) |
| ABSTRACT | The present disclosure generally relates to a solar cell device that includes a substrate comprising a front side surface and a backside surface; an epitaxial region overlying the substrate, wherein the epitaxial region comprises a first Bragg reflector disposed below a first solar cell, wherein the first solar cell has a first bandgap, wherein the first Bragg reflector is operable to reflect a first range of radiation wavelengths back into the first solar cell, and is operable to cool the solar cell device by reflecting a second range of radiation wavelengths that are outside the photogeneration wavelength range of the first solar cell or that are weakly absorbed by the first solar cell, and may additionally comprise a second Bragg reflector operable to reflect a third range of radiation wavelengths back into the first solar cell. |
| FILED | Tuesday, January 12, 2016 |
| APPL NO | 14/993690 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0547 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541349 | Stan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| INVENTOR(S) | Mark A. Stan (Albuquerque, New Mexico); Arthur Cornfeld (Sandia Park, New Mexico) |
| ABSTRACT | A method of manufacturing an inverted metamorphic multijunction solar cell is disclosed herein. The method includes forming a lattice constant transition material positioned between a first subcell and a second subcell using a metal organic chemical vapor deposition (MOCVD) reactor. The solar cell further includes at least one distributed Bragg reflector (DBR) layer directly adjacent a back surface field (BSF) layer. |
| FILED | Monday, April 29, 2013 |
| APPL NO | 13/872663 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/056 (20141201) H01L 31/184 (20130101) Original (OR) Class H01L 31/0549 (20141201) H01L 31/0725 (20130101) H01L 31/1844 (20130101) H01L 31/1892 (20130101) H01L 31/06875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541467 | Brigham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute Of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Glenn A. Brigham (Chelmsford, Massachusetts); David M. Bragdon (Merrimack, New Hampshire); Edward M. Froehlich (Somerville, Massachusetts) |
| ABSTRACT | A novel system for supporting a plurality of notch antenna elements is disclosed. This system allows the creation of higher power ultra-wideband step notch arrays. The system also provides electrical connection to each of the notch antenna elements via respective coaxial cables or other direct connections. These coaxial cables connect to coaxial connectors disposed on a substrate that supports the notch antenna elements. Each coaxial connector is in electrical communication with one of the notch antenna elements. By replacing the printed circuit board traditionally used, higher power can be supplied to the notch antenna elements. |
| FILED | Wednesday, February 22, 2017 |
| APPL NO | 15/439511 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 1/48 (20130101) H01Q 1/243 (20130101) Original (OR) Class H01Q 5/25 (20150115) H01Q 13/06 (20130101) H01Q 13/10 (20130101) H01Q 21/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541504 | Daniel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COMMONWEALTH OF AUSTRALIA represented by DEPARTMENT OF DEFENSE, DEFENSE SCIENCE AND TECHNOLOGY ORGANISATION (Edinburgh, Australia) |
| ASSIGNEE(S) | Commonwealth Of Australia represented by Department of Defence, Defence Science and Technology Organisation (Edinburgh, Australia) |
| INVENTOR(S) | Jae Daniel (Edinburgh, Australia); William Andrew Clarkson (Southampton, United Kingdom); Nikita Simakov (Edinburgh, Australia) |
| ABSTRACT | An active optical fibre, including: a core; an inner cladding substantially surrounding the core, whereby the core and the inner cladding form an area configured to propagate pump radiation; an outer cladding comprised of at least a third material with at least a third refractive index substantially surrounding the inner cladding, the third refractive index being smaller than the second refractive index, whereby the outer cladding confines pump radiation to the core and the inner cladding; and a coating comprised of a thermally conductive material substantially surrounding the outer cladding, wherein the inner cladding is configured to reduce impact of spatial hole-burning on absorption of the pump radiation as the pump radiation propagates through the active optical fibre, and wherein the thermally conductive material of the coating supports a reduced temperature increase between the area and an outer surface of the coating. |
| FILED | Monday, February 08, 2016 |
| APPL NO | 15/550012 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/04 (20130101) C03C 25/42 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02395 (20130101) G02B 6/03633 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/067 (20130101) H01S 3/0405 (20130101) Original (OR) Class H01S 3/06716 (20130101) H01S 3/06733 (20130101) H01S 3/06754 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541611 | Giuliano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David M. Giuliano (Cambridge, Massachusetts); David J. Perreault (Cambridge, Massachusetts); Robert C. N. Pilawa-Podgurski (Cambridge, Massachusetts) |
| ABSTRACT | A converter circuit and related technique for providing high power density power conversion includes a reconfigurable switched capacitor transformation stage coupled to a magnetic converter (or regulation) stage. The circuits and techniques achieve high performance over a wide input voltage range or a wide output voltage range. The converter can be used, for example, to power logic devices in portable battery operated devices. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/146028 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/07 (20130101) H02M 3/155 (20130101) H02M 3/158 (20130101) Original (OR) Class H02M 2001/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541658 | Zai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Andrew H. Zai (Sudbury, Massachusetts); Michael D. Lockard (Norwood, Massachusetts); Kenneth E. Kolodziej (Lexington, Massachusetts); Jeffrey S. Herd (Rowley, Massachusetts) |
| ABSTRACT | Systems and methods for improving power amplifier operation are provided. A system may include a baseband signal generator communicatively coupled to a baseband signal digital-to-analog converter. The baseband signal digital-to-analog converter may be communicatively coupled to two or more power amplifiers. The system may also include an envelope signal generator communicatively coupled to an envelope signal digital-to-analog converter. The system may further include a supply modulator communicatively coupled to the envelope signal digital-to-analog converter and the two or more power amplifiers for shared envelope tracking across the two or more power amplifiers. |
| FILED | Friday, December 15, 2017 |
| APPL NO | 15/843730 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Amplifiers H03F 1/0222 (20130101) H03F 1/0283 (20130101) H03F 1/3247 (20130101) Original (OR) Class H03F 3/19 (20130101) H03F 3/68 (20130101) H03F 3/245 (20130101) H03F 2200/102 (20130101) H03F 2200/451 (20130101) H03F 2201/3233 (20130101) Transmission H04B 1/406 (20130101) H04B 1/0458 (20130101) H04B 1/0475 (20130101) H04B 1/0483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541659 | Abdo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Baleegh Abdo (Carmel, New York); Katrina Sliwa (New Haven, Connecticut); Luigi Frunzio (North Haven, Connecticut); Robert J. Schoelkopf, III (Madison, Connecticut); Michel Devoret (New Haven, Connecticut) |
| ABSTRACT | A low-noise directional amplifier includes a first port, a second port, a first coupler and a second coupler. The first port is coupled to a first coupler. The low-noise directional amplifier also includes at least two phase preserving amplifiers, a first phase preserving amplifier connected to the first coupler and a second coupler, and the second phase preserving amplifier connected to the first coupler and the second coupler. |
| FILED | Wednesday, October 15, 2014 |
| APPL NO | 15/029666 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/223 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 5/18 (20130101) Amplifiers H03F 1/26 (20130101) H03F 3/195 (20130101) H03F 3/608 (20130101) H03F 7/00 (20130101) H03F 7/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541722 | Shmel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Richard Nicholas Shmel (Bentonville, Arkansas); Phillip E. Pace (San Juan Bautista, California) |
| ABSTRACT | Disclosed herein is a design, simulation, and hardware build of a photonic compressed sensing Nyquist folding receiver that is able to directly undersample wideband RF signals and detect the original Nyquist zone and frequency information. According to an exemplary embodiment, this is achieved by generating a frequency modulated optical impulse train for directly undersampling the RF environment at the antenna. The impulse train undersamples the signals using an optical modulator configuration at 1550 nm and collects the detected samples in a low pass interpolation filter which is subsequently processed to extract the undersampled signals. |
| FILED | Thursday, November 15, 2018 |
| APPL NO | 16/191871 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/7174 (20130101) H04B 1/71637 (20130101) Original (OR) Class H04B 2001/6912 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541803 | Prvulovic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Milos Prvulovic (Atlanta, Georgia); Nina Basta (Atlanta, Georgia); Robert Callan (Atlanta, Georgia); Alenka Zajic (Atlanta, Georgia) |
| ABSTRACT | Aspects of the disclosed technology provide a method comprising executing different first and second instructions a first and second number of times, respectively, in repeated alternations. The method further comprises measuring spectra of signals emanating as a result of the processor executing the first and second instructions. The method also includes analyzing data indicative of the spectra of the signals to determine side-channel candidate side-band pairs that each have a lower and upper sideband at first and second frequencies, respectively, that are separated by approximately twice the respective alternation frequency. Finally, the method includes identifying a side-channel carrier frequency at a frequency approximately at a midpoint between a side-channel candidate side-band pair's first and second frequency. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/023838 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/003 (20130101) Original (OR) Class H04L 2209/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541878 | He et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Ting He (Piermont, New York); Liang Ma (White Plains, New York); Erich M. Nahum (New York, New York); Mudhakar Srivatsa (White Plains, New York) |
| ABSTRACT | A computer-implemented method, computer program product, and computer processing system are provided for client-side monitoring in a cloud provider environment including a network having a plurality of nodes. The method includes estimating a logical topology of the network by clustering source-destination node pairs while excluding intermediate nodes from among the plurality of nodes based on end-to-end performance measurements between various ones of the plurality of nodes forming the source-destination node pairs. The method also includes at least one of scheduling and customizing a workload within the network, and executing the workload within the network, based on the estimated logical topology. |
| FILED | Thursday, July 19, 2018 |
| APPL NO | 16/039847 |
| ART UNIT | 2441 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 9/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/12 (20130101) Original (OR) Class H04L 41/5006 (20130101) H04L 41/5009 (20130101) H04L 41/5096 (20130101) H04L 43/08 (20130101) H04L 67/1002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10542312 | Bassett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Kevin S. Bassett (Nottingham, New Hampshire); Wojciech J. Krawiec (Amherst, New Hampshire) |
| ABSTRACT | The system can utilize a standard high speed FPGA interface for a non-traditional use to facilitate the processing of high amounts of streaming digital data or the method can be implemented in other high speed data transfer systems. This system and method include the use of training/calibration pattern techniques implemented in a FPGA, or other system, to calibrate numerous multi-arm demultiplexers. The training/calibration sequence data rate being slower than the input data rate. In one example, the system and method utilized a mono-bit receiver capable of digitizing signals of at least 40 GHz with at least 20 GHz of instantaneous bandwidth. |
| FILED | Friday, January 26, 2018 |
| APPL NO | 15/880897 |
| ART UNIT | 2465 — Multiplex and VoIP |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 21/4341 (20130101) Original (OR) Class H04N 21/4342 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D873290 | Burnett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Gregory M Burnett (Dayton, Ohio); Isaiah L Bragg (Xenia, Ohio); Noah W Bragg (Beavercreek, Ohio); Jared S Dewey (Tucson, Arizona); Matthew R. Weber (Beavercreek, Ohio) |
| ABSTRACT | |
| FILED | Tuesday, February 19, 2019 |
| APPL NO | 29/680658 |
| ART UNIT | 2916 — Design |
| CURRENT CPC | Recording, communication, or information retrieval equipment D14/486 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D873524 | Applegate et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Christopher Applegate (Andover, New Jersey); Jeffrey Van Derveer (Randolph, New Jersey); David Thomsen (Bethlehem, Pennsylvania) |
| ABSTRACT | |
| FILED | Friday, July 21, 2017 |
| APPL NO | 29/611294 |
| ART UNIT | 2911 — Design |
| CURRENT CPC | Material or article handling equipment D34/38 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 10537265 | Corum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Curtis A. Corum (Shoreview, Minnesota); Djaudat S. Idiyatullin (New Brighton, Minnesota); Steen Moeller (Golden Valley, Minnesota); Michael G. Garwood (Medina, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
| INVENTOR(S) | Curtis A. Corum (Shoreview, Minnesota); Djaudat S. Idiyatullin (New Brighton, Minnesota); Steen Moeller (Golden Valley, Minnesota); Michael G. Garwood (Medina, Minnesota) |
| ABSTRACT | A system includes a data receiver, a sinogram generator, a processor, a filter module, and an output module. The data receiver is configured to receive radial ordered magnetic resonance data. The sinogram generator is configured to generate a first sinogram corresponding to a view angle as a function of a readout direction for the magnetic resonance data. The processor is configured to generate an oscillogram having an angular frequency axis. The oscillogram corresponds to a Fourier transform of the first sinogram. The filter module is configured to selectively filter a peak in a projection formed along a selected axis of the oscillogram, the peak being related to an interference signal such as an RF interference. The selected axis is orthogonal to the angular frequency axis. The output module is configured to form a second sinogram corresponding to a transform of the filtered projection. |
| FILED | Thursday, March 31, 2011 |
| APPL NO | 13/638465 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/725 (20130101) A61B 5/742 (20130101) A61B 5/7225 (20130101) A61B 5/7257 (20130101) A61B 5/7278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537277 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); THOMAS JEFFERSON UNIVERSITY HOSPITALS, INC. (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Chengyuan Wu (Merion, Pennsylvania); Allan Azarion (Potomac, Maryland); Jue Wu (Pittsburgh, Pennsylvania); Ankit N. Khambhati (West Windsor, New Jersey); Joost Wagenaar (Rutledge, Pennsylvania); Brian Litt (Bala Cynwyd, Pennsylvania); Justin Blanco (Annapolis, Maryland) |
| ABSTRACT | The subject matter described herein relates to methods, systems, and computer readable media for visualization of a resection target during epilepsy surgery and for real time spatiotemporal visualization of neurophysiologic biomarkers. One exemplary method includes a real time neurophysiologic biomarker visualization system implemented by at least one computer, receiving, as input, a pre-electrode-implantation MRI of an epilepsy patient's brain. |
| FILED | Wednesday, May 28, 2014 |
| APPL NO | 14/894819 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0478 (20130101) A61B 5/04012 (20130101) A61B 5/4094 (20130101) Original (OR) Class A61B 5/4836 (20130101) A61B 5/7435 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) G01R 33/4812 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537283 | Caputo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Joshua M. Caputo (Pittsburgh, Pennsylvania); Steven H. Collins (Pittsburgh, Pennsylvania); Peter G. Adamcyzk (Ann Arbor, Michigan); Myunghee Kim (Pittsburgh, Pennsylvania); Tianjian Chen (Pittsburgh, Pennsylvania); Tianyao Chen (Washington, District of Columbia) |
| ABSTRACT | The present invention includes two embodiments of a tethered ankle-foot prosthesis, one with a single toe to provide plantarflexion and with two independently-actuated toes that are coordinated to provide plantarflexion and inversion-eversion torques. An end-effector was designed which is worn by a subject, and which was integrated with existing off-board motor and control hardware, to facilitate high bandwidth torque control. The platform is suitable for haptic rendering of virtual devices in experiments with humans, which may reveal strategies for improving balance or allow controlled comparisons of conventional prosthesis features. A similar morphology is also effective for autonomous devices. |
| FILED | Saturday, August 15, 2015 |
| APPL NO | 14/827299 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/08 (20130101) A61B 5/4851 (20130101) Original (OR) Class A61B 5/6811 (20130101) A61B 5/14542 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/66 (20130101) A61F 2/5046 (20130101) A61F 2/6607 (20130101) A61F 2002/503 (20130101) A61F 2002/701 (20130101) A61F 2002/704 (20130101) A61F 2002/763 (20130101) A61F 2002/6657 (20130101) A61F 2002/7625 (20130101) A61F 2002/7635 (20130101) A61F 2002/7645 (20130101) A61F 2002/7675 (20130101) A61F 2002/7695 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537337 | Gordon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); The United States of America; As represented by the Secretary of Defence, Walter Reed National Military Medical Center (Washington, District of Columbia); The United States of America; as Represented by the Secretary of the Navy, IP Counsel of the Navy Office of Naval Research (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chad Gordon (Lutherville, Maryland); Mehran Armand (Fulton, Maryland); Ryan Murphy (Columbia, Maryland); Gerald Grant (Goshen, Kentucky); Peter Liacouras (North Potomac, Maryland); Kevin Wolfe (Lutherville, Maryland) |
| ABSTRACT | A computer-assisted surgical system can include a donor sub-system and a recipient sub-system. The donor sub-system includes a first reference unit having a first trackable element, a fragment reference unit having a second trackable element, and a first detector configured to provide at least one of a first signal corresponding to a detected location of one or more of the first trackable element and the second trackable element. The recipient sub-system includes a second reference unit having a third trackable element, and a second detector configured to provide at least one of a second signal corresponding to a detected location of at least the third trackable element. |
| FILED | Tuesday, November 25, 2014 |
| APPL NO | 15/100258 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/15 (20130101) Original (OR) Class A61B 17/176 (20130101) A61B 17/1695 (20130101) A61B 17/1739 (20130101) A61B 17/8085 (20130101) A61B 34/10 (20160201) A61B 34/20 (20160201) A61B 2034/105 (20160201) A61B 2034/108 (20160201) A61B 2034/2051 (20160201) A61B 2034/2055 (20160201) A61B 2034/2065 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2803 (20130101) Electric Digital Data Processing G06F 19/3481 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537531 | Mao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Hui Mao (Johns Creek, Georgia); Jing Huang (Decatur, Georgia) |
| ABSTRACT | This disclosure relates to nanoparticle drug delivery systems composed of casein (CN) coated nanoparticles, e.g., iron oxide nanoparticles coated with an inner layer and an out layer comprising the milk protein casein. In certain embodiments, drug molecules are incorporated into an inner polymeric layer coating the nanoparticles, which are subsequently coated with a casein containing outer layer, i.e., a layer-by-layer (LBL) construction. Oral administration of these casein coated nanoparticles are contemplated as experiments indicated sufficiently stability in conditions that simulate the conditions of the gut. Drugs that were loaded into the nanoparticle systems were released when the casein outer layer was gradually degraded in the presence of an intestinal protease meant to simulate conditions of the intestine. |
| FILED | Wednesday, August 09, 2017 |
| APPL NO | 15/672666 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5115 (20130101) A61K 9/5138 (20130101) A61K 9/5169 (20130101) Original (OR) Class A61K 31/704 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537545 | Lutz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Richard Lutz (New Brunswick, New Jersey); Eric Andrianasolo (New Brunswick, New Jersey); Paul Falkowski (New Brunswick, New Jersey); Eileen White (New Brunswick, New Jersey); Liti Haramaty (New Brunswick, New Jersey) |
| ABSTRACT | The invention provides a compound of formula (I): (I) wherein R1-R4 have any of the values defined in the specification, as well as compositions comprising a compound of formula (I) and methods for treating diseases (e.g. cancer). |
| FILED | Tuesday, July 19, 2016 |
| APPL NO | 15/746368 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/22 (20130101) A61K 31/164 (20130101) A61K 31/164 (20130101) A61K 31/232 (20130101) Original (OR) Class A61K 31/336 (20130101) A61K 31/352 (20130101) A61K 31/352 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 233/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537553 | Burkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the Nevada System of Higher Education, on Behalf of the University of Nevada, Reno (Reno, Nevada) |
| ASSIGNEE(S) | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (Reno, Nevada) |
| INVENTOR(S) | Dean Burkin (Sparks, Nevada); Ryan Wuebbles (Sparks, Nevada) |
| ABSTRACT | Disclosed herein are α7β1 integrin modulatory agents and methods of using such to treat conditions associated with decreased α7β1 integrin expression or activity, including muscular dystrophy. In one example, methods for treating a subject with muscular dystrophy are disclosed. The methods include administering an effective amount of an α7β1 integrin modulatory agent to the subject with muscular dystrophy, wherein the α7β1 integrin modulatory agent increases α7β1 integrin expression or activity as compared to α7β1 integrin expression or activity prior to treatment, thereby treating the subject with muscular dystrophy. Also disclosed are methods of enhancing muscle regeneration, repair, or maintenance in a subject and methods of enhancing α7β1 integrin expression by use of the disclosed α7β1 integrin modulatory agents. Methods of prospectively preventing or reducing muscle injury or damage in a subject are also disclosed. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/236244 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) Original (OR) Class A61K 31/404 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537557 | Raffay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Thomas M. Raffay (Cleveland, Ohio); Benjamin M. Gaston (Cleveland, Ohio) |
| ABSTRACT | A method of treating a hyperoxia induced disease or disorder associated with GSNO deficiency in a subject in need thereof includes administering to the subject a therapeutically effective amount of GSNO or a GSNO promoting agent. |
| FILED | Friday, January 27, 2017 |
| APPL NO | 15/418126 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4178 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537574 | Kalman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Daniel Kalman (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to the use of kinase inhibitor to treat or prevent infectious diseases such as tuberculosis. In certain embodiments, this disclosure relates to treating or preventing an infectious disease comprising administering an effective amount of a kinase inhibitor or other compound disclosed herein to a subject in need thereof. In certain embodiments, the disclosure relates to methods of treating or preventing tuberculosis comprising administering a kinase inhibitor to a subject in need thereof. In certain embodiments, the subject is diagnosed with Mycobacterium tuberculosis (Mtb) that is resistant to multiple antibiotic agents. |
| FILED | Friday, September 16, 2016 |
| APPL NO | 15/760978 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537577 | Boden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); The United States Government as represented by the Department of Veterans Affairs (Atlanta, Georgia) |
| INVENTOR(S) | Scott D. Boden (Atlanta, Georgia); Sreedhara Sangadala (Atlanta, Georgia) |
| ABSTRACT | The disclosure relates to compounds and compositions for forming bone and methods related thereto. In one embodiment, the disclosure relates to a composition comprising a compound disclosed herein, such as 2,4-diamino-1,3,5-triazine derivatives or salts thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement. |
| FILED | Thursday, November 02, 2017 |
| APPL NO | 15/801964 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) Original (OR) Class A61K 31/53 (20130101) A61K 38/1875 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 2300/412 (20130101) A61L 2430/02 (20130101) Heterocyclic Compounds C07D 251/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537598 | Connolly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BIOGAIA AB (Stockholm, Sweden); Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan); BIOGAIA AB (Stockholm, Sweden) |
| INVENTOR(S) | Eamonn Connolly (Lindingö, Sweden); Robert Allen Britton (East Lansing, Michigan); Laura Rae McCabe (Haslett, Michigan) |
| ABSTRACT | The present invention comprises a method for selecting lactic acid bacterial strains effective for preventing bone loss in humans and strains that have been selected according to the presented method. The selection method is based on the strains capability of reestablishing an altered microbial community to normal and/or harboring at least one of four specific SNPs. |
| FILED | Wednesday, January 23, 2019 |
| APPL NO | 16/254994 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/135 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2002/00 (20130101) A23V 2200/306 (20130101) Indexing Scheme Relating to Lactic or Propionic Acid Bacteria Used in Foodstuffs or Food Preparation A23Y 2220/00 (20130101) A23Y 2220/71 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/59 (20130101) A61K 35/747 (20130101) Original (OR) Class A61K 2035/11 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537599 | Miles et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Linde Miles (New York, New York); John Poirier (New York, New York); Charles Rudin (New York, New York) |
| ABSTRACT | A method for selecting cancer patient for treatment with Seneca Valley Virus (SVV) by determining expression of ANTXR1 in a cancerous tissue in a cancer patient; and designating the cancer patient as a candidate for treatment with SVV if normal levels or elevated levels of ANTXR1 expression is detected in the cancerous tissue. Also a method for treating a cancer patient with SVV is disclosed. |
| FILED | Friday, December 02, 2016 |
| APPL NO | 15/780898 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/768 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/32033 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537609 | Lillehoj et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Erik P. Lillehoj (West Friendship, Maryland); Avelino C. Verceles (Elkridge, Maryland); Simeon E. Goldblum (Baltimore, Maryland) |
| ABSTRACT | Pseudomonas aeruginosa flagellin protein recruits the mammalian host sialidase enzyme neuraminidase-1 (NEU1) to remove sialic acid residues from the extracellular domain of the mammalian cell-surface protein MUC1 (MUC1-ED), thereby exposing a cryptic binding site on the MUC1-ED protein backbone for flagellin binding. NEU1-driven MUC1-ED desialylation rapidly increases P. aeruginosa adhesion to the airway epithelium. MUC1-ED desialylation also increases MUC1-ED cleavage and shedding from the cell surface, where desialylated, shed MUC1-ED competitively blocks P. aeruginosa adhesion to cell-associated MUC1-ED. Presented herein are data showing that exogenously-administered, deglycosylated MUC1-ED peptides reduced adhesion of P. aeruginosa to airway epithelial cells. Also presented are data showing that administration of P. aeruginosa to mice in combination with deglycosylated MUC1-ED decreased P. aeruginosa recovered from the lungs at 48 hr and 72 hr post-infection. Such findings are extended to the methods of treatment and prevention of bacterial infections defined herein. |
| FILED | Thursday, June 22, 2017 |
| APPL NO | 15/630165 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/546 (20130101) A61K 38/00 (20130101) A61K 38/1735 (20130101) Original (OR) Class Peptides C07K 14/4727 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 33/56916 (20130101) G01N 2333/21 (20130101) G01N 2333/195 (20130101) G01N 2333/245 (20130101) G01N 2333/4725 (20130101) Technologies for Adaptation to Climate Change Y02A 50/47 (20180101) Y02A 50/473 (20180101) Y02A 50/478 (20180101) Y02A 50/481 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537613 | Volkman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Brian Volkman (Muskego, Wisconsin); Joshua Ziarek (Boston, Massachusetts); Christopher Veldkamp (Milwaukee, Wisconsin); Francis Peterson (Racine, Wisconsin) |
| ABSTRACT | The present invention provides a CXCL121 peptide engineered to resist peptide-induced dimerization by maintaining steric repulsion of the chemokine helix, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS. |
| FILED | Thursday, January 18, 2018 |
| APPL NO | 15/874476 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/195 (20130101) Original (OR) Class Peptides C07K 14/521 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537627 | Putnam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | David A. Putnam (Ithaca, New York); Joseph Rosenthal (Ithaca, New York); Chung-Jr Huang (Newbury Park, California); Matthew DeLisa (Ithaca, New York); Susana Mendez (Silver Spring, Maryland) |
| ABSTRACT | The present invention relates to a probiotic cell transformed with a construct suitable to overexpress and display on the surface of the probiotic cell a fusion protein comprising at least a portion of a transport protein coupled to at least a portion of one or more antigenic proteins or peptides. Probiotic-derived vesicles displaying this fusion protein as well as methods of inducing an immune response using the probiotic cells or vesicles are also disclosed. |
| FILED | Wednesday, September 20, 2017 |
| APPL NO | 15/709976 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) A61K 39/04 (20130101) A61K 39/12 (20130101) A61K 39/015 (20130101) Original (OR) Class A61K 39/35 (20130101) A61K 39/38 (20130101) A61K 39/39 (20130101) A61K 39/145 (20130101) A61K 2039/52 (20130101) A61K 2039/523 (20130101) A61K 2039/6068 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537641 | Kobayashi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The USA as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Hisataka Kobayashi (Laurel, Maryland); Peter Choyke (Rockville, Maryland) |
| ABSTRACT | The present disclosure relates to compositions and methods of killing cells. In particular examples, the method includes contacting a cell having a cell surface protein with a therapeutically effective amount of an antibody-IR700 molecule, wherein the antibody specifically binds to the cell surface protein, such as a tumor-specific antigen on the surface of a tumor cell. The cell is subsequently irradiated, such as at a wavelength of 660 to 740 nm at a dose of at least 1 J cm−2. The cell is also contacted with one or more therapeutic agents (such as an anti-cancer agent), for example about 0 to 8 hours after irradiating the cell, thereby killing the cell. Also provided are methods of imaging cell killing in real time, using fluorescence lifetime imaging. Also provided are wearable devices that include an article of clothing, jewelry, or covering; and an NIR LED incorporated into the article, which can be used with the disclosed methods. |
| FILED | Monday, September 28, 2015 |
| APPL NO | 14/868040 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/0002 (20130101) A41D 2400/32 (20130101) Personal Adornments, e.g Jewellery; Coins A44C 15/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 41/0071 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 47/6803 (20170801) A61K 47/6869 (20170801) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/32 (20130101) C07K 16/2863 (20130101) C07K 16/3069 (20130101) C07K 2317/24 (20130101) C07K 2317/73 (20130101) C07K 2317/77 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537650 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Brian D. Gray (Malvern, Pennsylvania); Mary Rusckowski (Southborough, Massachusetts); Koon Y. Pak (Malvern, Pennsylvania) |
| ABSTRACT | The invention relates to novel multi-modality probes for imaging, tracking and analyzing stem cells and related biological samples, and methods of preparation and use thereof. The molecular probes of the invention are constructed, for example, by utilizing (a) the high selectivity of long hydrocarbon chains for binding to plasma membranes of cells, (b) a near-infrared (NIR) dye for optical imaging, and (c) a radionuclide for PET or SPECT imaging. The in vitro and in vivo data of the optical and radiolabeled probes demonstrated their utility for detecting the presence of stem cells with multiple imaging modalities. |
| FILED | Monday, November 14, 2016 |
| APPL NO | 15/350389 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 51/0446 (20130101) A61K 51/0478 (20130101) A61K 51/0482 (20130101) A61K 51/0485 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) Heterocyclic Compounds C07D 209/14 (20130101) C07D 209/20 (20130101) C07D 403/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/52 (20130101) G01N 33/582 (20130101) G01N 33/5005 (20130101) G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537718 | Lederman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Henry Ford Health System (Detroit, Michigan) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Henry Ford Health System (Detroit, Michigan) |
| INVENTOR(S) | Robert Jay Lederman (Chevy Chase, Maryland); Ozgur Kocaturk (Rockville, Maryland); Adam Brett Greenbaum (Detroit, Michigan) |
| ABSTRACT | Technology disclosed herein provides a reduced transition between the edge of a rigid vascular dilator and the distal edge of the accompanying introducer sheath. Disclosed dilators can be segmented into two or more primarily longitudinally extending parts, can have rigid circumferential or semi-circumferential leading shoulders to minimize the transition between the dilator and the sheath edge, and can contain internal recesses to allow sequential retraction of segments once the introducer sheath is delivered to a target chamber. With this technology, vascular introducer sheaths can be introduced percutaneously into a broad range of diseased target vessels and chambers with reduced damage to the wall of the vessel or chamber, and with reduced damage to the distal end of the introducer sheath. |
| FILED | Monday, October 13, 2014 |
| APPL NO | 15/025336 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00234 (20130101) A61B 17/3478 (20130101) A61B 2017/00247 (20130101) A61B 2017/00336 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0662 (20130101) A61M 29/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538028 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | John A. Rogers (Champaign, Illinois); Sheng Xu (Urbana, Illinois); Zheng Yan (Urbana, Illinois); Yihui Zhang (Evanston, Illinois); Yonggang Huang (Glencoe, Illinois) |
| ABSTRACT | Origami- and Kirigami-inspired assembly of predetermined three-dimensional forms is presented in comprehensive theoretical and experimental studies, with examples of a broad range of topologies and material compositions. The resulting engineering options in the construction of functional 3D structures have important implications for advanced microsystem technologies. |
| FILED | Tuesday, November 17, 2015 |
| APPL NO | 14/944039 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 61/006 (20130101) B29C 61/0616 (20130101) Original (OR) Class Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/756 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/00 (20130101) B32B 27/40 (20130101) B32B 27/283 (20130101) B32B 27/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538491 | Conn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | P. Jeffrey Conn (Nashville, Tennessee); Craig W. Lindsley (Brentwood, Tennessee); Kyle A. Emmitte (Aledo, Texas); Andrew S. Felts (Brentwood, Tennessee); Katrina A. Bollinger (Murfreesboro, Tennessee) |
| ABSTRACT | 4,5-Substituted Picolinamide and picolinonitrile compounds of formula (I), where R4 is CONH2 or CN and R1 is an optionally substituted aryl or heteroaryl, are negative allosteric modulators of the metabotropic glutamate receptor 2 (mGlu2). The compounds and pharmaceutical compositions including the compounds may be useful for treating depression, anxiety, obsessive-compulsive disorder, cognitive disorders, Alzheimer's disease, or autism spectrum disorders in a subject. |
| FILED | Wednesday, March 16, 2016 |
| APPL NO | 15/558788 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/02 (20130101) A61K 31/165 (20130101) A61K 31/277 (20130101) Heterocyclic Compounds C07D 213/81 (20130101) Original (OR) Class C07D 213/84 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 405/12 (20130101) C07D 413/06 (20130101) C07D 413/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538509 | MacMillan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | David W. C. MacMillan (Princeton, New Jersey); Zhiwei Zuo (Plainsboro, New Jersey) |
| ABSTRACT | Methods described herein enable the production of numerous molecular species through decarboxylative cross-coupling via use of photoredox and transition metal catalysts. A method described herein, in some embodiments, comprises providing a reaction mixture including a photoredox catalyst, a transition metal catalyst, a coupling partner and a substrate having a carboxyl group. The reaction mixture is irradiated with a radiation source resulting in cross-coupling of the substrate and coupling partner via a mechanism including decarboxylation, wherein the coupling partner is selected from the group consisting of a substituted aromatic compound and a substituted aliphatic compound. |
| FILED | Friday, March 27, 2015 |
| APPL NO | 15/301692 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 211/27 (20130101) Heterocyclic Compounds C07D 207/06 (20130101) C07D 207/08 (20130101) C07D 209/14 (20130101) C07D 211/08 (20130101) C07D 265/30 (20130101) C07D 401/04 (20130101) C07D 403/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538527 | Gangjee |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania) |
| ABSTRACT | The present invention provides a compound of Formula II, and salts thereof, and a pharmaceutical composition comprising a compound of Formula II: wherein R is hydrogen or an alkyl group having from one to ten carbon atoms, and wherein R3 is hydrogen, an alkyl group having from one to ten carbon atoms, or a halogen. Preferably the compound of Formula II includes wherein R3 is a halogen, and most preferably wherein the halogen is chlorine. Methods of treating a patient with cancer with these compounds are also provided. |
| FILED | Monday, February 04, 2019 |
| APPL NO | 16/266928 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 239/94 (20130101) C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538534 | Williams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Robert M. Williams (Fort Collins, Colorado); James E. Bradner (Weston, Massachusetts); Dane Clausen (Rahway, New Jersey); Olaf G. Wiest (South Bend, Indiana); Le Zhao (Fort Collins, Colorado); Christine Elizabeth Dunne (Fort Collins, Colorado) |
| ABSTRACT | Analogs of largazole are described herein. Methods of treating cancer, blood disorders, autoimmune disease, and Alzheimer's Disease using largazole analogs and pharmaceutical compositions comprising the same are additionally described herein. Methods for preparing largazole analogs are likewise described. |
| FILED | Friday, March 04, 2016 |
| APPL NO | 15/555792 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/429 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 513/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538546 | Beaucage et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland) |
| INVENTOR(S) | Serge L. Beaucage (Silver Spring, Maryland); Andrzej Grajkowski (Kensington, Maryland) |
| ABSTRACT | The invention provides a compound of the formula: and a capture support of the formula: wherein R1, R2, R3, R6, A, B, D, E, J, K, Q, W, and Z are as defined herein. The invention also provides a method of purifying an oligonucleotide or an oligonucleotide analog composed of “b” nucleotides from a mixture comprising the oligonucleotide or oligonucleotide analog and at least one oligonucleotide or oligonucleotide analog composed of “a” nucleotides, wherein b≠a, comprising use of the compound and the capture support. |
| FILED | Wednesday, June 28, 2017 |
| APPL NO | 16/312445 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/103 (20130101) B01J 20/3204 (20130101) B01J 20/3246 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/06 (20130101) Original (OR) Class C07H 21/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538556 | McNaughton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado); University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado); University of Rochester (Rochester, New York) |
| INVENTOR(S) | Brian R. McNaughton (Fort Collins, Colorado); David W. Crawford (Fort Collins, Colorado); Joseph E. Wedekind (Rochester, New York); Ivan A. Belashov (Rochester, New York) |
| ABSTRACT | Simple β-hairpin peptides in linear and cyclic form that specifically bind to HIV-1 Trans-Activation Response element (HIV-1 TAR), as well as compositions and use thereof are described. |
| FILED | Tuesday, November 07, 2017 |
| APPL NO | 15/805933 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 7/50 (20130101) C07K 7/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538570 | Leonard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Joshua N. Leonard (Wilmette, Illinois); Michelle E. Hung (Chicago, Illinois) |
| ABSTRACT | Disclosed are exosomes that include a packaging protein and a cargo RNA in which the packaging protein binds specifically to the cargo RNA. The packaging protein is a fusion protein that includes an RNA-binding domain and an exosome-targeting domain. The cargo RNA includes an RNA-motif that the RNA-binding domain of the fusion protein binds specifically such that the cargo RNA is packaged in the lumen of the exosomes. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 14/502494 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 2319/85 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538572 | Schmitt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| INVENTOR(S) | Thomas M. Schmitt (Seattle, Washington); Philip D. Greenberg (Mercer Island, Washington); Hieu Nguyen (Federal Way, Washington) |
| ABSTRACT | The present disclosure provides high affinity and enhanced affinity T cell receptors specific for human Wilms tumor protein 1 (WT-1) epitopes for use in treating diseases or disorders, such as cancer cells that overexpress WT-1. |
| FILED | Thursday, July 30, 2015 |
| APPL NO | 14/813782 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) A61K 38/1774 (20130101) A61K 38/2013 (20130101) A61K 38/2013 (20130101) A61K 38/2086 (20130101) A61K 38/2086 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/7051 (20130101) Original (OR) Class C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538574 | Bleakley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| ASSIGNEE(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| INVENTOR(S) | Marie Bleakley (Seattle, Washington); Robson Dossa (Shoreline, Washington); Daniel Sommermeyer (Munich, Germany) |
| ABSTRACT | The present disclosure provides compositions and methods for targeting a minor histocompatibility (H) antigen (HA-1H) to, for example, prevent or manage relapse of a hematological malignancy after allogeneic hematopoietic stem cell transplantation (HCT). Also provided are transgene constructs encoding engineered binding proteins, such as a T cell receptor or a chimeric antigen receptor, optionally encoding additional components such as a co-receptor and/or safety switch. Such transgene constructs can be transduced into an immune cell, such as a T cell, and used as an immunotherapy in a subject having a hematological malignancy or at risk for recurrence of the hematological malignancy (e.g., leukemia, lymphoma, myeloma). |
| FILED | Friday, March 22, 2019 |
| APPL NO | 16/362551 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Peptides C07K 14/7051 (20130101) Original (OR) Class C07K 14/70517 (20130101) C07K 2319/41 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538578 | Raguram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | S. Raguram (Hillsborough, New Jersey); Viswanathan Sasisekharan (Cambridge, Massachusetts); Venkataramanan Soundararajan (Windham, New Hampshire); Ram Sasisekharan (Lexington, Massachusetts); Vidya Subramanian (Somerville, Massachusetts); Kannan Tharakaraman (Woburn, Massachusetts) |
| ABSTRACT | The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza. |
| FILED | Monday, April 23, 2018 |
| APPL NO | 15/959430 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538588 | Adusumilli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); The U.S.A. as Represented by the Secretary, Department Of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); THE U.S.A. AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Prasad S. Adusumilli (New York, New York); Michel Sadelain (New York, New York); Dimiter S. Dimitrov (Frederick, Maryland); Yang Feng (Frederick, Maryland) |
| ABSTRACT | The presently disclosed subject matter provides for methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to chimeric antigen receptors (CARs) that specifically target human mesothelin, and immunoresponsive cells comprising such CARs. The presently disclosed mesothelin-targeted CARs have enhanced immune-activating properties, including anti-tumor activity. |
| FILED | Wednesday, May 16, 2018 |
| APPL NO | 15/981142 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/705 (20130101) C07K 14/4748 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 2317/21 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538590 | Kobayashi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Hisataka Kobayashi (Laurel, Maryland); Peter Choyke (Rockville, Maryland) |
| ABSTRACT | The present disclosure relates to compositions and methods of killing cells in vitro or in vivo. In particular examples, the method includes contacting a cell having a cell surface protein with a therapeutically effective amount of an antibody-IR700 molecule, wherein the antibody specifically binds to the cell surface protein. In particular examples the antibody recognizes a tumor-specific antigen on the surface of a tumor cell. The cell is subsequently irradiated, such as at a wavelength of 660 to 740 nm at a dose of at least 1 J cm−2, thereby killing the cell. Also provided are wearable devices that include an article of clothing, jewelry, or covering; and an NIR LED incorporated into the article, which can be used with the disclosed methods. |
| FILED | Wednesday, August 21, 2013 |
| APPL NO | 13/972532 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/0002 (20130101) A41D 2400/32 (20130101) Personal Adornments, e.g Jewellery; Coins A44C 15/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 41/0071 (20130101) A61K 47/6803 (20170801) A61K 47/6869 (20170801) A61K 49/0032 (20130101) A61K 49/0058 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/30 (20130101) Original (OR) Class C07K 16/32 (20130101) C07K 16/2863 (20130101) C07K 16/3069 (20130101) C07K 2317/24 (20130101) C07K 2317/73 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538591 | Viapiano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Mariano S. Viapiano (Syracuse, New York); Nandhu Mohan Sobhana (Syracuse, New York); Ennio Antonio Chiocca (Weston, Massachusetts) |
| ABSTRACT | Embodiments described herein provide anti-fibulin-3 antibodies, recombinant proteins that bind specifically to fibulin-3, compositions and the treatment methods comprising these antibodies and recombinant proteins. |
| FILED | Tuesday, March 10, 2015 |
| APPL NO | 15/124826 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/17 (20130101) A61K 31/166 (20130101) A61K 31/166 (20130101) A61K 31/175 (20130101) A61K 31/175 (20130101) A61K 31/475 (20130101) A61K 31/475 (20130101) A61K 31/495 (20130101) A61K 31/495 (20130101) A61K 39/3955 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 49/0021 (20130101) A61K 2039/54 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/5158 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/22 (20130101) C07K 16/30 (20130101) Original (OR) Class C07K 16/3053 (20130101) C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0646 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538726 | Wikswo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Ronald S. Reiserer (Nashville, Tennessee); Kyle Hawkins (Nashville, Tennessee) |
| ABSTRACT | A system for microdialysis imaging and regional fluidic delivery and control includes a microdialysis imager including a imaging head having N pixels aligned in a pixel array for monitoring a living bio-object associated with the pixel array; and a fluidic module coupled to the microdialysis imager for delivering a fluidic substance to and collecting effluent from the living bio-object, including a fluidic network having a plurality of valves, a plurality of fluidic channels in fluidic communication with the plurality of valves and one or more pumps coupled to corresponding fluidic channels, and a microcontroller coupled to the fluidic network for individually controlling the plurality of valves and the one or more pumps of the fluidic network as so to operably and selectively deliver the fluidic substance to and continuously collect the effluent from the living bio-object responsive to the delivered fluidic substance via each pixel in real time. |
| FILED | Monday, April 29, 2019 |
| APPL NO | 16/397019 |
| ART UNIT | 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0247 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502715 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 23/44 (20130101) C12M 23/58 (20130101) C12M 25/02 (20130101) C12M 29/00 (20130101) C12M 29/10 (20130101) C12M 41/36 (20130101) C12M 41/48 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 19/006 (20130101) F04B 43/12 (20130101) F04B 43/0045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538738 | Papoutsakis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eleftherios Papoutsakis (Newark, Delaware); Chen-Yuan Kao (Newark, Delaware); Jinlin Jiang (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eleftherios Papoutsakis (Newark, Delaware); Chen-Yuan Kao (Newark, Delaware); Jinlin Jiang (Gaithersburg, Maryland) |
| ABSTRACT | Applications in transfusion medicine requiring platelets, and hematopoietic stem-cell transplantations require either platelets or enhancement of in vivo platelet biogenesis. Gene therapy applications of hematopoietic stem and progenitor cells (HSPCs) require effective and specific modification of HSPCs by DNA, RNA or other biological molecules. Here we disclose methods for the generation, and modification of megakaryocytic microparticles (MkMPs) or microvesicles, that can be used in the aforementioned transfusion and transplantation medicine applications and in gene therapy applications involving hematopoietic stem cells. The biological effects of modified or unmodified MkMPs have never been previously disclosed and thus, this invention claims all biological applications of MkMPs in in vivo therapeutic applications or ex vivo applications to produce various cells and cell parts, modify various target cells or deliver molecules including drugs to HSPCs and related cells. |
| FILED | Monday, May 18, 2015 |
| APPL NO | 15/308221 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/19 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0644 (20130101) Original (OR) Class C12N 2521/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538743 | Kaczmarczyk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Stanislaw J. Kaczmarczyk (Frederick, Maryland); Deb K. Chatterjee (Potomac, Maryland) |
| ABSTRACT | Described herein are compositions relating to alphavirus-based virus-like particles (VLPs) and methods for making and using the described VLPs. The described compositions include VLPs and vectors and cells used to produce the VLPs. Also included are related methods to produce the VLPs, to transduce cells using the VLPs, and to produce a protein or polynucleotide of interest in a target cell using the VLPs. Also described are alphavirus-based replicons that allow for expression of proteins or polynucleotides of interest in a target cell without a cytopathic effect. |
| FILED | Thursday, June 23, 2016 |
| APPL NO | 15/190992 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) A61K 38/1774 (20130101) A61K 48/0066 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/141 (20130101) C12N 2320/32 (20130101) C12N 2740/11022 (20130101) C12N 2740/11023 (20130101) C12N 2740/11042 (20130101) C12N 2740/11051 (20130101) C12N 2740/13022 (20130101) C12N 2740/13051 (20130101) C12N 2770/36123 (20130101) C12N 2770/36143 (20130101) C12N 2770/36145 (20130101) C12N 2770/36152 (20130101) C12N 2800/24 (20130101) C12N 2810/6081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538762 | Corey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | David Corey (Dallas, Texas); Jiaxin Hu (Coppell, Texas) |
| ABSTRACT | Provided herein are compositions and methods for reducing expression of C9orf72 transcripts in cells containing expanded intronic GGGGCC regions, including those in subjects having or at risk of developing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Provided herein are a double-stranded oligonucleotides of 13 to 22 nucleobases in length targeting a GGGGCC expanded repeat region in an intron of C9orf72, comprises (a) 3-5 central mismatches (within bases 9-14) within a target sequence comprising the expanded repeat sequence, or (h) 3-5 mismatches outside of the seed sequence (bases 2-8 within the guide strand complementary to the expanded repeat sequence). |
| FILED | Thursday, October 08, 2015 |
| APPL NO | 15/518824 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/3231 (20130101) C12N 2320/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538763 | Rigo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California); Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California); Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Frank Rigo (Carlsbad, California); Stephen J. Tapscott (Seattle, Washington) |
| ABSTRACT | The present disclosure pertains generally to double-stranded small interfering RNAs that modulate gene expression for use in research, diagnostics, and/or therapeutics. In certain embodiments, the present disclosure provides double-stranded small interfering RNAs that modulate DUX4 gene expression. In certain embodiments, the present disclosure provides methods of inhibiting DUX4 gene expression by contacting a cell with double-stranded small interfering RNAs. |
| FILED | Friday, January 15, 2016 |
| APPL NO | 15/540903 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/32 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/351 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538766 | Jo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Hanjoong Jo (Marietta, Georgia); Dongju Son (Decatur, Georgia); Wakako Takabe (Atlanta, Georgia); Sandeep Kumar (Atlanta, Georgia); Hhaiwei Qiu (Decatur, Georgia); Chanwoo Kim (Decatur, Georgia) |
| ABSTRACT | This disclosure relates to methods and compositions for managing vascular conditions by targeting microRNA. In certain embodiments, the disclosure relates to antisense, RNA interference, and blocking oligonucleotide therapeutic compositions and uses related thereto. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/107936 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 31/713 (20130101) A61K 45/06 (20130101) A61K 47/55 (20170801) A61K 47/61 (20170801) A61K 47/64 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/04 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 31/125 (20130101) A61L 31/148 (20130101) A61L 2300/258 (20130101) A61L 2420/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/31 (20130101) C12N 2310/113 (20130101) C12N 2310/314 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/351 (20130101) C12N 2310/3125 (20130101) C12N 2310/3181 (20130101) C12N 2310/3231 (20130101) C12N 2310/3233 (20130101) C12N 2310/3341 (20130101) C12N 2310/3513 (20130101) C12N 2320/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538773 | Park et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Hee-Sung Park (Daejeon, South Korea); Dieter Soll (Guilford, Connecticut) |
| ABSTRACT | Nucleic acids encoding mutant elongation factor proteins (EF-Sep), phosphoseryl-tRNA synthetase (SepRS), and phosphoseryl-tRNA (tRNASep) and methods of use in site specific incorporation of phosphoserine into a protein or polypeptide are described. Mutant EF-Sep proteins are disclosed that bind Sep-tRNASep and protect Sep-tRNASep from deacylation. In a preferred embodiment the nucleic acids are on vectors and are expressed in cells such as bacterial cells, archeaebacterial cells, and eukaryotic cells. Proteins or polypeptides containing phosphoserine produced by the methods described herein can be used for a variety of applications such as research, antibody production, protein array manufacture and development of cell-based screens for new drug discovery. |
| FILED | Wednesday, February 22, 2017 |
| APPL NO | 15/439449 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/245 (20130101) C07K 14/435 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) C12N 15/67 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) C12P 21/02 (20130101) Enzymes C12Y 601/01027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538794 | Ju et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Tongzhong Ju (Atlanta, Georgia); Richard Cummings (Boston, Massachusetts); Matthew Kudelka (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to libraries of oligosaccharides comprising multiple individual oligosaccharides derived from cells that contain a tag or detectable marker. In certain embodiments, the tag or detectable marker is an oxygen linked to the oligosaccharides through the first carbon of a sugar ring. In certain embodiments, the disclosure relates to methods of generating the libraries of oligosaccharides using saccharides, e.g., monosaccharides, or a disaccharide, in which hydroxyl groups are chemically acetylated. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 15/826387 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538807 | Bielas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Jason H. Bielas (Seattle, Washington); Sean D. Taylor (Kirkland, Washington); Matthew T. Laurie (Olympia, Washington) |
| ABSTRACT | The present disclosure relates to compositions and methods for detecting rare nucleic acid molecule mutations in a plurality of nucleic acid molecules. Also disclosed are methods for determining the size of a nucleic acid molecule using droplet digital PCR. |
| FILED | Wednesday, May 29, 2013 |
| APPL NO | 14/402820 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538813 | Sarwal |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Minnie M. Sarwal (Portola Valley, California) |
| ABSTRACT | Methods are provided for monitoring a subject having a graft for an acute rejection (AR) response, e.g., to predict, to diagnose, and/or to characterize an AR response. In practicing the subject methods, the expression level of at least one gene in a sample from the subject, e.g., a blood or biopsy sample, is evaluated, e.g., at the nucleic acid and/or protein level, to monitor the subject. Also provided are compositions, systems, kits and computer program products that find use in practicing the subject methods. |
| FILED | Wednesday, February 21, 2018 |
| APPL NO | 15/901803 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539508 | Suslick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Kenneth S. Suslick (Champaign, Illinois); Jon R. Askim (Urbana, Illinois) |
| ABSTRACT | A portable device for colorimetric or fluorometric analysis comprises a linear array of optically-responsive chemical sensing elements; an image sensor in optical communication with the linear array for determining a spectral response of the optically-responsive chemical sensing elements, where the image sensor comprises at least one light emission source; and electronics connected to the image sensor for analyzing spectral response data. A method of conducting colorimetric or fluorometric analysis comprises exposing a linear array of optically-responsive chemical sensing elements to a fluid comprising an analyte; impinging light on the linear array and detecting a spectral response of the chemical sensing elements; and determining an exposed color of each of the chemical sensing elements. |
| FILED | Tuesday, June 09, 2015 |
| APPL NO | 15/317840 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Original (OR) Class G01N 21/80 (20130101) G01N 2021/7773 (20130101) G01N 2021/7786 (20130101) G01N 2021/7793 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539554 | Ben-Yakar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Adela Ben-Yakar (Austin, Texas); Evan Hegarty (Austin, Texas); Sudip Mondal (Austin, Texas); Navid Ghorashian (Sunnyvale, California); Sertan Kutal Gökçe (Austin, Texas); Christopher Martin (Austin, Texas) |
| ABSTRACT | A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, may be controlled via hydraulic pressure. |
| FILED | Tuesday, October 27, 2015 |
| APPL NO | 15/522116 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502723 (20130101) B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 2300/14 (20130101) B01L 2300/023 (20130101) B01L 2300/0654 (20130101) B01L 2300/0864 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/05 (20130101) G01N 21/6458 (20130101) G01N 33/502 (20130101) G01N 33/5085 (20130101) Original (OR) Class G01N 35/00029 (20130101) G01N 35/00871 (20130101) G01N 2021/6482 (20130101) G01N 2035/00148 (20130101) G01N 2201/12 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/00134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539572 | Bapat et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California) |
| ASSIGNEE(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California) |
| INVENTOR(S) | Sagar P. Bapat (La Jolla, California); Ye Zheng (La Jolla, California); Ronald Evans (La Jolla, California); Michael Downes (La Jolla, California); Annette R. Atkins (La Jolla, California); Ruth T. Yu (La Jolla, California) |
| ABSTRACT | The invention features compositions and methods treating or preventing for age-related insulin resistance, type 2 diabetes and related disorders. The method involves depleting fTreg cells with an anti-ST2 antibody to decrease age-related fTreg accumulation and restore insulin sensitivity, thereby treating age-related insulin resistance, type 2 diabetes and related disorders. |
| FILED | Tuesday, January 12, 2016 |
| APPL NO | 15/544385 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/395 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Peptides C07K 16/28 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/6869 (20130101) Original (OR) Class G01N 2333/7155 (20130101) G01N 2800/042 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540570 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Rakesh Shiradkar (Cleveland, Ohio); Soumya Ghose (University Heights, Ohio) |
| ABSTRACT | Embodiments predict prostate cancer (PCa) biochemical recurrence (BCR) employing an image acquisition circuit that accesses a first pre-treatment image and a second pre-treatment image of a region of tissue demonstrating PCa, a distension feature circuit that extracts a set of distension features from the first pre-treatment image, and computes a first probability of PCa BCR based on the set of distension features, a radiomics circuit that extracts a set of radiomics features from the second pre-treatment image, and computes a second probability of PCa recurrence based on the set of radiomics feature, a combined tumor induced organ distension with tumor radiomics (COnTRa) circuit that computes a joint probability that the region of tissue will experience PCa BCR based on the first probability and the second probability, and a display circuit that displays the joint probability. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 15/923495 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4381 (20130101) A61B 5/4842 (20130101) A61B 5/7267 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/685 (20130101) G06K 9/6221 (20130101) G06K 9/6227 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/174 (20170101) G06T 7/337 (20170101) G06T 2207/10096 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30081 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540992 | Goldhor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Speech Technology and Applied Research Corporation (Lexington, Massachusetts); Richard S. Goldhor (Belmont, Massachusetts) |
| ASSIGNEE(S) | Richard S. Goldhor (Belmont, Massachusetts); Speech Technology and Applied Research Corporation (Lexington, Massachusetts) |
| INVENTOR(S) | Richard S. Goldhor (Belmont, Massachusetts); Keith Gilbert (Berlin, Massachusetts); Joel MacAuslan (Nashua, New Hampshire) |
| ABSTRACT | A system processes data signals consisting of sums of independent signal terms, zero or more of which signal terms may already have been identified, in order to generate one or more additional terms. Deflated versions of the data signals are created by subtracting from the data signals any previously identified signal terms. Additional independent signal terms are computed using a set of reference signals organized into mutually independent partioning support sets. The images of each support set are computed on the data signals. Computed images on a data signal that are non-zero are identified as additional independent signal terms of that data signal. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/019873 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/51 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10542209 | Seibel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Eric J. Seibel (Seattle, Washington); Brian T. Schowengerdt (Seattle, Washington) |
| ABSTRACT | Methods and systems for acquiring and/or projecting images from and/or to a target area are provided. Such a method or system can includes an optical fiber assembly which may be driven to scan the target area in a scan pattern. The optical fiber assembly may provide multiple effective light sources (e.g., via a plurality of optical fibers) that are axially staggered with respect to an optical system located between the optical fiber and the target area. The optical system may be operable to focus and/or redirect the light from the multiple light sources onto separate focal planes. A composite image may be generated based on light reflected from and/or projected onto the separate focal planes. The composite image may have an extended depth of focus or field spanning over a distance between the separate focal planes while maintaining or improving image resolution. |
| FILED | Monday, July 10, 2017 |
| APPL NO | 15/645350 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/07 (20130101) A61B 1/00167 (20130101) A61B 1/00172 (20130101) A61B 1/00188 (20130101) A61B 1/0623 (20130101) Optical Elements, Systems, or Apparatus G02B 23/26 (20130101) G02B 23/2469 (20130101) G02B 26/103 (20130101) G02B 27/40 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 21/142 (20130101) Pictorial Communication, e.g Television H04N 5/23212 (20130101) H04N 5/23235 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10537089 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri); Heartland Farm Energy LLC (Boonville, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri); Heartland Farm Energy LLC (Boonville, Missouri) |
| INVENTOR(S) | Tingsheng Xu (Columbia, Missouri); Yunsheng Xu (Columbia, Missouri) |
| ABSTRACT | A system and method for thermally exchanging heat between waste air being expelled from a poultry barn and fresh outside/outdoor ambient air being introduced into the poultry barn. |
| FILED | Wednesday, November 16, 2016 |
| APPL NO | 15/353192 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 1/0076 (20130101) Original (OR) Class Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 7/1623 (20130101) F28D 21/0014 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 9/26 (20130101) F28F 9/187 (20130101) F28F 21/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537823 | Baxter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Larry Baxter (Orem, Utah); Christopher Hoeger (Provo, Utah); Eric Mansfield (Spanish Fork, Utah); Kyler Stitt (Lindon, Utah); Stephanie Burt (Provo, Utah); Nathan Davis (Bountiful, Utah) |
| ASSIGNEE(S) | Hall Labs LLC (Provo, Utah) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); Christopher Hoeger (Provo, Utah); Eric Mansfield (Spanish Fork, Utah); Kyler Stitt (Lindon, Utah); Stephanie Burt (Provo, Utah); Nathan Davis (Bountiful, Utah) |
| ABSTRACT | A method for removing carbon dioxide from a carrier liquid using a heat exchanger. A carrier liquid, containing carbon dioxide, is heated through the heat exchanger, causing the carbon dioxide to vaporize. The carrier liquid and the carbon dioxide gas pass to a liquid removal vessel. The carrier liquid is removed and the carbon dioxide gas is compressed. The compressed carbon dioxide gas is provided to the heat exchanger, cooling the carbon dioxide gas opposite the carrier liquid, producing a carbon dioxide liquid. |
| FILED | Wednesday, February 15, 2017 |
| APPL NO | 15/433185 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537828 | Baxter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Larry Baxter (Orem, Utah); Andrew Baxter (Spanish Fork, Utah); Kyler Stitt (Lindon, Utah); Aaron Sayre (Spanish Fork, Utah); Stephanie Burt (Provo, Utah); David Frankman (Provo, Utah); Nathan Davis (Bountiful, Utah) |
| ASSIGNEE(S) | Sustainable Energy Solutions, LLC (Orem, Utah) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); Andrew Baxter (Spanish Fork, Utah); Kyler Stitt (Lindon, Utah); Aaron Sayre (Spanish Fork, Utah); Stephanie Burt (Provo, Utah); David Frankman (Provo, Utah); Nathan Davis (Bountiful, Utah) |
| ABSTRACT | A method for preventing fouling of a demister is disclosed. A process fluid is provided into a vessel. A gas is provided to a gas inlet of the vessel. The gas comprises a component that desublimates, crystallizes, solidifies, reacts, or a combination thereof, in the process fluid, forming a first solid. The gas is passed through the process fluid, the component of the gas forming the first solid, resulting in a component-depleted gas. The component-depleted gas is passed out of the process fluid, causing splashing or spurting of the process fluid and the first solid. The diverter section is provided between the demister and the gas inlet, the diverter section comprising a physical obstruction preventing the process fluid and the first solid from splashing or spurting onto the demister. In this manner, fouling of the demister is prevented. |
| FILED | Wednesday, April 12, 2017 |
| APPL NO | 15/485569 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 1/305 (20130101) B01D 5/00 (20130101) Original (OR) Class B01D 5/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537831 | Kaduchak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Gregory Kaduchak (Los Alamos, New Mexico); Greg Goddard (Los Alamos, New Mexico); Gary Salzman (White Rock, New Mexico); Dipen Sinha (Los Alamos, New Mexico); John C Martin (Los Alamos, New Mexico); Christopher Kwiatkowski (Los Alamos, New Mexico); Steven Graves (San Juan Pueblo, New Mexico) |
| ABSTRACT | The present invention includes an apparatus and corresponding method for concentrating analytes within a fluid flowing through a tube using acoustic radiation pressure. The apparatus includes a function generator that outputs a radio frequency electrical signal to a transducer that transforms the radio frequency electric signal to an acoustic signal and couples the acoustic signal to the tube. The acoustic signal is converted within the tube to acoustic pressure that concentrates the analytes within the fluid. |
| FILED | Wednesday, June 03, 2015 |
| APPL NO | 14/729244 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Separation B01D 21/28 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 2001/4094 (20130101) G01N 2015/142 (20130101) G01N 2015/1413 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/206 (20150401) Y10T 137/0324 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537839 | Fleming et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Darryn Fleming (Albuquerque, New Mexico); Salvador B. Rodriguez (Albuquerque, New Mexico) |
| ABSTRACT | A media-free filter device for a supercritical fluid process is disclosed. The media-free filter device includes a first pipe section connected in flow communication with a closed-loop system for a supercritical fluid. A y-pipe segment intersects the first pipe section at an intersection joint. The intersection joint intersects at a descending obtuse angle with respect to the first pipe section flow direction. The y-pipe segment is open at the intersection joint and closed opposite the intersection joint, in flow communication with the first pipe section. The y-pipe section induces an eddy current turbulence zone adjacent the intersection joint to remove substantially all contaminants suspended in the supercritical fluid; and the contaminants are deposited in the descending y-pipe segment. An SCO2 process incorporating the media-free filter device is also disclosed. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 15/825852 |
| ART UNIT | 3748 — Printing/Measuring and Testing |
| CURRENT CPC | Separation B01D 45/06 (20130101) Original (OR) Class Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 7/16 (20130101) F01K 21/06 (20130101) F01K 25/103 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 1/04 (20130101) F02C 1/10 (20130101) F02C 1/105 (20130101) F02C 7/05 (20130101) F02C 7/052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537843 | Baxter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Larry Baxter (Orem, Utah); Kyler Stitt (Lindon, Utah); Stephanie Burt (Provo, Utah); Christopher Hoeger (Provo, Utah); Eric Mansfield (Spanish Fork, Utah); Nathan Davis (Bountiful, Utah) |
| ASSIGNEE(S) | Hall Labs LLC (Provo, Utah) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); Kyler Stitt (Lindon, Utah); Stephanie Burt (Provo, Utah); Christopher Hoeger (Provo, Utah); Eric Mansfield (Spanish Fork, Utah); Nathan Davis (Bountiful, Utah) |
| ABSTRACT | A process for separating a mixture of components is disclosed. A liquid mixture is provided to a separation vessel substantially near a temperature at which a product component freezes. The liquid mixture comprises the product component and a carrier component. The product component and the carrier component are essentially immiscible substantially near the temperature. The liquid mixture is separated into two or more phases, the two or more phases comprising a product component-rich liquid phase and a product component-depleted liquid phase. In this manner, a mixture of components is separated. |
| FILED | Tuesday, April 25, 2017 |
| APPL NO | 15/496307 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 17/02 (20130101) B01D 53/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537858 | Darling et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Seth B. Darling (Chicago, Illinois); Anna Lee (Darien, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Joseph A. Libera (Clarendon Hills, Illinois) |
| ABSTRACT | A porous membrane provides enhanced filtration of pollutants and particles by coating the membrane with conformal thin films of doped titanium dioxide via atomic layer deposition or, alternatively, sequential infiltration synthesis. The membrane can either be organic or inorganic, and the doping of the membrane, usually with nitrogen, is an important feature that shifts the optical absorption of the TiO2 from the UV range into the visible-light range. This enables the use of lower energy light, including sunlight, to activate the photocatalytic function of the film. The coating described in the present invention is compatible with virtually any porous membrane and allows for precise tuning of the pore size with molecular precision. The present invention presents a new coating process and chemical structure that provides catalytic activity, strongly enhanced by light, to both mitigate fouling and break down various organic pollutants in the process stream. |
| FILED | Wednesday, January 20, 2016 |
| APPL NO | 15/002102 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/027 (20130101) B01D 61/145 (20130101) B01D 61/147 (20130101) B01D 67/0093 (20130101) B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 69/125 (20130101) Original (OR) Class B01D 71/16 (20130101) B01D 71/022 (20130101) B01D 71/024 (20130101) B01D 2323/02 (20130101) B01D 2323/40 (20130101) B01D 2323/46 (20130101) B01D 2325/10 (20130101) B01D 2325/36 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/442 (20130101) C02F 1/444 (20130101) C02F 2101/30 (20130101) C02F 2303/20 (20130101) C02F 2305/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538028 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | John A. Rogers (Champaign, Illinois); Sheng Xu (Urbana, Illinois); Zheng Yan (Urbana, Illinois); Yihui Zhang (Evanston, Illinois); Yonggang Huang (Glencoe, Illinois) |
| ABSTRACT | Origami- and Kirigami-inspired assembly of predetermined three-dimensional forms is presented in comprehensive theoretical and experimental studies, with examples of a broad range of topologies and material compositions. The resulting engineering options in the construction of functional 3D structures have important implications for advanced microsystem technologies. |
| FILED | Tuesday, November 17, 2015 |
| APPL NO | 14/944039 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 61/006 (20130101) B29C 61/0616 (20130101) Original (OR) Class Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/756 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/00 (20130101) B32B 27/40 (20130101) B32B 27/283 (20130101) B32B 27/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538439 | Doerrer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Linda H. Doerrer (Cambridge, Massachusetts); Steven F. Hannigan (Boston, Massachusetts); Laleh Tahsini (Stillwater, Oklahoma); Christopher M. Kotyk (Acton, Massachusetts) |
| ABSTRACT | A method for reducing nitrates, nitrites, and/or hydroxylamine in water using a homogeneous reduced copper tetra-substituted fluorinated pinacolate ligand catalyst complex. The method includes dissolving a copper(II) tetra-substituted fluorinated pinacolate ligand pre-catalyst complex in water having an excess amount of nitrates, nitrites, and/or hydroxylamine therein. The dissolved copper(II) tetra-substituted fluorinated pinacolate ligand pre-catalyst complex in the water is subjected to electrochemical reduction to form a homogeneous reduced copper tetra-substituted fluorinated pinacolate ligand catalyst complex. The homogeneous reduced copper tetra-substituted fluorinated pinacolate ligand catalyst complex reduces the nitrates, nitrites, and/or hydroxylamine in the water to compounds with nitrogen in a lower oxidation state with the homogeneous reduced copper tetra-substituted fluorinated pinacolate ligand catalyst complex. |
| FILED | Friday, January 29, 2016 |
| APPL NO | 15/545088 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/223 (20130101) B01J 31/1625 (20130101) B01J 31/1633 (20130101) B01J 37/348 (20130101) B01J 2231/70 (20130101) B01J 2531/16 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/70 (20130101) Original (OR) Class C02F 1/4676 (20130101) C02F 2101/163 (20130101) C02F 2101/166 (20130101) C02F 2103/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538441 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Redwood City, California) |
| INVENTOR(S) | Chong Liu (Palo Alto, California); Yi Cui (Stanford, California) |
| ABSTRACT | Catalytic water treatment is provided using an active material driven with an optical and/or electrical excitation. The active material is MoS2, MoSe2, WS2, WSe2, MoxW1-xS2, MoxW1-xSe2, MoSySe2-y, WSySe2-y, or MoxW1-xSySe2-y; wherein 0<x<1 and 0<y<2. The active material is configured as one or more layered nanostructures having exposed layer edges. A metal catalyst is disposed on the active material. The combined structure of active material and metal catalyst is disposed in the water to be treated. The excitation is provided to the active material to generate one or more reactive oxygen species by dissociation of water, wherein the reactive oxygen species provide water treatment. |
| FILED | Wednesday, September 21, 2016 |
| APPL NO | 15/761556 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/32 (20130101) C02F 1/725 (20130101) Original (OR) Class C02F 1/4672 (20130101) C02F 1/46109 (20130101) C02F 2001/46142 (20130101) C02F 2201/009 (20130101) C02F 2303/04 (20130101) C02F 2305/10 (20130101) C02F 2305/023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538451 | Angel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Roger P. Angel (Tucson, Arizona); Thomas E. Stalcup, Jr. (Tucson, Arizona) |
| ABSTRACT | A system for shaping glass or metal sheets or panels for use in solar collectors or microwave antennae may include an oven and an adjustable mold. The adjustable mold may comprise a molding surface located within the oven. The molding surface may be coupled to position actuators located outside of the oven via coupling elements. A sheet or panel may be placed in the oven and heated until the sheet or panel softens and takes the shape of the molding surface. The molding surface may be adjusted to achieve different shapes for glass or metal sheets or panels. |
| FILED | Friday, September 01, 2017 |
| APPL NO | 15/694327 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 23/0252 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538464 | Dagle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| INVENTOR(S) | Vanessa Dagle (Richland, Washington); Karl O. Albrecht (Richland, Washington); Robert A. Dagle (Richland, Washington) |
| ABSTRACT | A system and process for processing biologically-derived compounds or a complex bio-oil by converting cyclic compounds in a complex bio-oil or biologically-derived compounds to desired materials such as high molecular weight paraffins with minimal carbon loss by using a ring-contraction catalyst to selectively produce C5 ring containing compounds; and then reacting the C5 ring containing compounds with a C5 ring opening catalyst in a second reactor to minimize carbon loss via cracking reactions. |
| FILED | Friday, October 19, 2018 |
| APPL NO | 16/165198 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/245 (20130101) Acyclic or Carbocyclic Compounds C07C 4/06 (20130101) Original (OR) Class C07C 2521/04 (20130101) C07C 2523/46 (20130101) C07C 2529/74 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 11/04 (20130101) C10G 2300/1014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538549 | Hang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bo Hang (Lafayette, California); Ahmed Chenna (Sunnyvale, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bo Hang (Lafayette, California); Ahmed Chenna (Sunnyvale, California) |
| ABSTRACT | NNA-derived specific adducts represent an integrated biomarker of exposure to thirdhand smoke (THS) as NNA is unique to THS. The NNA-dG covalent binding adduct could serve as such a biomarker, and play a role in identifying individuals exposed to THS, thus providing critical information for early detection and prevention. |
| FILED | Monday, March 16, 2015 |
| APPL NO | 14/659588 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/16 (20130101) Original (OR) Class C07H 19/23 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538632 | Kaehr |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Bryan James Kaehr (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to a method of forming silica nanolayers on or within a biological sample, thereby capturing structural details that are present in the sample. The resultant silica composite or silica replica, in turn, can be employed as a template for a replica having those structural details captured in a polymer. Also provided herein are synthetic constructs including a polymeric replica, which can have any useful feature (e.g., oxygen-binding capacity). |
| FILED | Friday, September 30, 2016 |
| APPL NO | 15/282511 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/80 (20130101) A61K 49/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/001 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538695 | Cannan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carbo Ceramics Inc. (Houston, Texas); Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | CARBO CERAMICS INC. (Houston, Texas) |
| INVENTOR(S) | Chad Cannan (Cypress, Texas); Lewis Bartel (Albuquerque, New Mexico); Terrence Palisch (Richardson, Texas); David Aldridge (Albuquerque, New Mexico) |
| ABSTRACT | Electrically conductive proppants and methods for detecting, locating, and characterizing same are provided. The electrically conductive proppant can include a substantially uniform coating of an electrically conductive material having a thickness of at least 500 nm. The method can include injecting a hydraulic fluid into a wellbore extending into a subterranean formation at a rate and pressure sufficient to open a fracture therein, injecting into the fracture a fluid containing the electrically conductive proppant, electrically energizing the earth at or near the fracture, and measuring three dimensional (x, y, and z) components of electric and magnetic field responses at a surface of the earth or in an adjacent wellbore. |
| FILED | Friday, January 09, 2015 |
| APPL NO | 14/593447 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/805 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/06 (20130101) C23C 14/35 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/25 (20130101) E21B 43/26 (20130101) E21B 47/00 (20130101) E21B 47/0905 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538701 | Smartt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Heidi A. Smartt (Albuquerque, New Mexico); Dianna S. Blair (Albuquerque, New Mexico); Juan A. Romero (Bayfield, Colorado); Patrick L. Feng (Livermore, California) |
| ABSTRACT | A fluorescent composition includes at least one of a fluorescent sensor compound and organic reporter molecules encapsulated in a microsphere structure. When encapsulated, the fluorescent sensor compound and the organic reporter molecules are distributed in a liquid organic matrix. When non-encapsulated, the remaining one of the fluorescent sensor compound and the organic reporter molecules reside in the matrix. In response to a force applied to the composition sufficient to break at least a portion of the microsphere structure, the fluorescent sensor compound and the organic reporter molecules are transformed into a non-reversible fluorescent state exhibiting a quantum yield greater than 0.2. The fluorescent state is objectively visually verifiable without physically contacting the composition. |
| FILED | Monday, February 19, 2018 |
| APPL NO | 15/898906 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Heterocyclic Compounds C07D 311/82 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 6/00 (20130101) C09B 15/00 (20130101) C09B 57/02 (20130101) C09B 57/14 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/07 (20130101) Original (OR) Class C09K 11/54 (20130101) C09K 11/58 (20130101) C09K 11/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538753 | Brunecky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainably Enegry, LLC (Golden, Colorado) |
| INVENTOR(S) | Roman Brunecky (Arvada, Colorado); Venkataramanan Subramanian (Arvada, Colorado); Stephen Robert Decker (Berthoud, Colorado); Michael E. Himmel (Littleton, Colorado) |
| ABSTRACT | Disclosed herein are methods of making multifunctional microbial cellulases. The engineered multifunctional microbial cellulases disclosed herein exhibit improved activity over native cellulases. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 15/913620 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) Enzymes C12Y 302/01004 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/343 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538860 | Maldonado et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbot, Michigan) |
| INVENTOR(S) | Stephen Maldonado (Ann Arbor, Michigan); Joshua DeMuth (Ann Arbor, Michigan); Eli Fahrenkrug (Ann Arbor, Michigan) |
| ABSTRACT | Electrochemical liquid phase epitaxy (ec-LPE) processes and devices are provided that can form precipitated epitaxial crystalline films or layers on a substrate. The precipitated films may comprise a semiconductor, such as germanium, silicon, or carbon. Dissolution into, saturation within, and precipitation of the semiconductor from a liquid metal electrode (e.g., Hg pool) near an interface region with a substrate yields a polycrystalline semiconductor material deposited as an epitaxial film. Reactor cells for use in an electrochemical liquid phase epitaxy (ec-LPE) device are also provided that include porous membranes to facilitate formation of the precipitated epitaxial crystalline films. |
| FILED | Tuesday, January 09, 2018 |
| APPL NO | 15/865432 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 19/06 (20130101) C30B 19/12 (20130101) Original (OR) Class C30B 19/103 (20130101) C30B 29/04 (20130101) C30B 29/06 (20130101) C30B 29/08 (20130101) C30B 30/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02532 (20130101) H01L 21/02623 (20130101) H01L 21/02628 (20130101) H01L 21/28176 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/36 (20130101) H01M 8/06 (20130101) H01M 10/02 (20130101) H01M 2300/0002 (20130101) H01M 2300/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538990 | Bourcier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | William L. Bourcier (Livermore, California); Sarah K. Roberts (Livermore, California); Jeffery J. Roberts (Livermore, California); Souheil M. Ezzedine (Berkeley, California); Jonathan D. Hunt (Dublin, California) |
| ABSTRACT | A system for blocking fast flow paths in geological formations includes preparing a solution of colloidal silica having a nonviscous phase and a solid gel phase. The solution of colloidal silica is injected into the geological formations while the solution of colloidal silica is in the nonviscous phase. The solution of colloidal silica is directed into the fast flow paths and reaches the solid gel phase in the fast flow paths thereby blocking flow of fluid in the fast paths. |
| FILED | Friday, January 19, 2018 |
| APPL NO | 15/875183 |
| ART UNIT | 3674 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/5045 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 33/13 (20130101) Original (OR) Class E21B 41/0064 (20130101) Geothermal Collectors; Geothermal Systems F24T 10/20 (20180501) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/14 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539010 | Gutierrez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Transocean Innovation Labs Ltd. (Grand Cayman, Cayman Islands, Cayman Islands) |
| ASSIGNEE(S) | Transocean Innovation Labs Ltd. (Grand Cayman, Cayman Islands) |
| INVENTOR(S) | Jose Gutierrez (Houston, Texas); Luis Pereira (Houston, Texas) |
| ABSTRACT | A subsea processor may be located near the seabed of a drilling site and used to coordinate operations of underwater drilling components. The subsea processor may be enclosed in a single interchangeable unit that fits a receptor on an underwater drilling component, such as a blow-out preventer (BOP). The subsea processor may issue commands to control the BOP and receive measurements from sensors located throughout the BOP. The subsea processor may relay information to the surface for recording or monitoring. The subsea processor may also be programmed with a model from which to base operation of the BOP, such as in emergency conditions. |
| FILED | Wednesday, October 16, 2013 |
| APPL NO | 14/055669 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 7/12 (20130101) E21B 33/063 (20130101) E21B 33/064 (20130101) E21B 47/122 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539382 | Baxter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Larry Baxter (Orem, Utah); Aaron Sayre (Spanish Fork, Utah); Eric Mansfield (Spanish Fork, Utah); Nathan Davis (Bountiful, Utah) |
| ASSIGNEE(S) | Hall Labs LLC (Provo, Utah) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); Aaron Sayre (Spanish Fork, Utah); Eric Mansfield (Spanish Fork, Utah); Nathan Davis (Bountiful, Utah) |
| ABSTRACT | An apparatus comprising a heat exchanger and one or more induction heating elements is disclosed. The heat exchanger comprises a coolant side conduit and a process side conduit, the process side conduit being susceptible to fouling by at least partial desublimation, condensation, crystallization, deposition, or combinations thereof of a fouling component of a circulating process fluid. An electrically conductive first metal is disposed adjacent to the process side conduit. The one or more induction heating elements are disposed proximate to the heat exchanger. The one or more induction heating elements are connected to a source of electrical current. When the electrical current flows through the induction heating elements, eddy currents are induced in the first metal, heating the first metal such that the fouling component sublimates, melts, absorbs, or a combination thereof into the circulating process fluid. |
| FILED | Thursday, May 11, 2017 |
| APPL NO | 15/592680 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 7/00 (20130101) F28D 9/00 (20130101) Cleaning of Internal or External Surfaces of Heat-exchange or Heat-transfer Conduits, e.g Water Tubes or Boilers F28G 13/005 (20130101) Original (OR) Class F28G 15/003 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/108 (20130101) H05B 2214/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539783 | Birch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Gabriel Carlisle Birch (Albuquerque, New Mexico); Charles Fredrick LaCasse, IV (Albuquerque, New Mexico); Amber Lynn Dagel (Albuquerque, New Mexico); Jon D. Bradley (Albuquerque, New Mexico) |
| ABSTRACT | A system or method for designing optical systems includes generating a mathematical model of an imaging system; tracing a plurality of light rays from a source through the model of the imaging system in a forward direction and a backward direction incident upon an arbitrarily defined detector location; calculating the total light rays incident upon the arbitrarily defined detector location in response to the plurality of light rays; tracing a series of calibration images first through the computational or compressive imager mathematical model; measuring an output set of parameters based on a plurality of detected rays calibration images at the defined detector location; storing the output set of parameters in software, and determining an estimated system transfer function. |
| FILED | Monday, October 17, 2016 |
| APPL NO | 15/295614 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/0012 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/5009 (20130101) G06F 2217/16 (20130101) Image Data Processing or Generation, in General G06T 7/0004 (20130101) G06T 7/80 (20170101) G06T 2207/30108 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540200 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Kevin Y. Cheng (Austin, Texas); David A. Roberts (Boxborough, Massachusetts); William C. Brantley (Austin, Texas) |
| ABSTRACT | A hardware context manager in a field-programmable gate array (FPGA) device includes configuration logic configured to program one or more programming regions in the FPGA device based on configuration data for implementing a target configuration of the one or more programming regions. Context management logic in the hardware context manager is coupled with the configuration logic and saves a first context corresponding to the target configuration by retrieving first state information from the set of one or more programming regions, where the first state information is generated based on the target configuration, and storing the retrieved first state information in a context memory. The context management logic restores the first context by transferring the first state information from the context memory to the one or more programming regions, and causing the configuration logic to program the one or more programming regions based on the configuration data. |
| FILED | Friday, November 10, 2017 |
| APPL NO | 15/809940 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/461 (20130101) Original (OR) Class G06F 9/5016 (20130101) G06F 13/4022 (20130101) G06F 13/4282 (20130101) G06F 2213/0026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540304 | Sadowski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Greg Sadowski (Cambridge, Massachusetts); Tri Minh Nguyen (Pflugerville, Texas) |
| ABSTRACT | Systems, apparatuses, and methods for reducing the toggle rates on buses are disclosed. A computing system includes a source which provides packets for transmission on a bus. The packet is compressed by a compression engine. The compressed data format of the packet includes locations (bit positions) referred to as holes which do not include valid data. A bus configuration module identifies the locations of the holes and replaces the holes with information from a previous packet transmitted earlier on the bus. The bus configuration module also determines a new transmission bus width for the packet for lowering the bus toggle rate on the bus during transmission. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 15/581516 |
| ART UNIT | 2185 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 13/1678 (20130101) Original (OR) Class G06F 13/4072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540737 | Artico et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Fausto Artico (Santo Stino di Livenza, Italy); Jose R. Brunheroto (Mohegan Lake, New York); Juan Gonzalez Garcia (Yorktown Heights, New York); Nelson Mimura Gonzalez (Yorktown Heights, New York) |
| ABSTRACT | Methods for estimating accelerator performance for dynamic hardware behaviors are disclosed. Computer program code to be executed on a first processing unit is received, and an execution of the computer code on the first processing unit is monitored to determine a plurality of performance characteristics. A plurality of dynamic hardware behaviors is determined by applying a clustering algorithm to the performance characteristics, and an equivalent accelerator portion of computer code to be executed on a second processing unit is generated by translating a set of instructions in a first portion of computer code corresponding to a first one of the plurality of dynamic hardware behaviors to an equivalent set of instructions to be executed on the second processing unit. An estimated measure of performance for executing the equivalent accelerator portion on the second processing unit is determined for the first one of the plurality of dynamic hardware behaviors. |
| FILED | Friday, December 22, 2017 |
| APPL NO | 15/852450 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 1/324 (20130101) G06F 1/325 (20130101) G06F 11/3409 (20130101) G06F 2201/805 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 1/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541070 | Benedict et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | Haier US Appliance Solutions, Inc. (Wilmington, Delaware); UT-Batelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Michael Alexander Benedict (Louisville, Kentucky); Ayyoub Mehdizadeh Momen (Knoxville, Tennessee) |
| ABSTRACT | A method for forming a stabilized bed of magneto-caloric material is provided. The method includes aligning magneto-caloric particles within the casing while a magnetic field is applied to the magneto-caloric particles and then fixing positions of the magneto-caloric particles within the casing. A related stabilized bed of magneto-caloric material is also provided. |
| FILED | Monday, April 25, 2016 |
| APPL NO | 15/137049 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/015 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541074 | Büttner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Felix Büttner (Goettingen, Germany); Ivan Lemesh (Cambridge, Massachusetts); Geoffrey S. D. Beach (Winchester, Massachusetts) |
| ABSTRACT | A system and a method for the deterministic generation of magnetic skyrmions includes a magnetic strip configured to store and transport skyrmions. The magnetic strip includes one or more spatial inhomogeneities configured to generate a skyrmion at known locations when excited by a current pulse. A current pulse generator is used to inject current pulses into the magnetic strip via contact pads electrically coupled to both the current pulse generator and the magnetic strip. The system also includes a magnetic field source to apply an out-of-plane magnetic field across the magnetic strip to facilitate generation of skyrmions. Skyrmions can be generated by applying an out-of-plane magnetic field to the magnetic strip and injecting a current pulse with sufficient current density towards the spatial inhomogeneities. Once a skyrmion is generated, another current pulse with sufficient current density can be injected to move the skyrmion. |
| FILED | Friday, May 04, 2018 |
| APPL NO | 15/971206 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/18 (20130101) G11C 11/161 (20130101) G11C 11/1675 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/329 (20130101) H01F 10/3259 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) H01L 43/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541109 | Stanfill et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| INVENTOR(S) | Bryan A. Stanfill (Richland, Washington); Sarah M. Reehl (Richland, Washington); Margaret C. Johnson (Cary, North Carolina); Lisa M. Bramer (Kennewick, Washington); Nigel D. Browning (Richland, Washington); Andrew J. Stevens (Richland, Washington); Libor Kovarik (West Richland, Washington) |
| ABSTRACT | Disclosed are methods for sensing conditions of an electron microscope system and/or a specimen analyzed thereby. Also disclosed are sensor systems and electron microscope systems able to sense system conditions, and/or conditions of the specimen being analyzed by such systems. In one embodiment, a sparse dataset can be acquired from a random sub-sampling of the specimen by an electron beam probe of the electron microscope system. Instrument parameters, specimen characteristics, or both can be estimated from the sparse dataset. |
| FILED | Wednesday, July 26, 2017 |
| APPL NO | 15/660096 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/06 (20130101) H01J 37/244 (20130101) H01J 37/265 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541134 | Kurley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | James Kurley (Chicago, Illinois); Hao Zhang (Urbana, Illinois); Dmitri V. Talapin (Riverside, Illinois); Jake Russell (Arlington, Tennessee); Margaret Hervey Hudson (Chicago, Illinois) |
| ABSTRACT | Halometallate-capped semiconductor nanocrystals and methods for making the halometallate-capped semiconductor nanocrystals are provided. Also provided are methods of using solutions of the halometallate-capped semiconductor nanocrystals as precursors for semiconductor film formation. When solutions of the halometallate ligand-capped semiconductor nanocrystals are annealed, the halometallate ligands can act as grain growth promoters during the sintering of the semiconductor nanocrystals. |
| FILED | Wednesday, November 02, 2016 |
| APPL NO | 15/772258 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/2023 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0256 (20130101) H01L 21/02554 (20130101) H01L 21/02562 (20130101) H01L 21/02601 (20130101) H01L 21/02628 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541306 | O'Loughlin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael John O'Loughlin (Chapel Hill, North Carolina); Lin Cheng (Chapel Hill, North Carolina); Albert Augustus Burk, Jr. (Chapel Hill, North Carolina); Anant Kumar Agarwal (Chapel Hill, North Carolina); Alexander Suvorov (Durham, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Michael John O'Loughlin (Chapel Hill, North Carolina); Lin Cheng (Chapel Hill, North Carolina); Albert Augustus Burk, Jr. (Chapel Hill, North Carolina); Anant Kumar Agarwal (Chapel Hill, North Carolina); Alexander Suvorov (Durham, North Carolina) |
| ABSTRACT | A semiconductor die and a process for fabricating the semiconductor die are disclosed. The semiconductor die has a substrate and a silicon carbide (SiC) epitaxial structure on the substrate. The SiC epitaxial structure includes at least a first N-type SiC layer, at least a first P-type SiC layer, and carbon vacancy reduction material, which has been implanted into a surface of the SiC epitaxial structure. Further, the SiC epitaxial structure has been annealed to mobilize the carbon vacancy reduction material to diffuse carbon atoms substantially throughout the SiC epitaxial structure, thereby increasing an average carrier lifetime in the SiC epitaxial structure. |
| FILED | Wednesday, September 12, 2012 |
| APPL NO | 13/610993 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/322 (20130101) H01L 21/02664 (20130101) H01L 21/26506 (20130101) H01L 21/26513 (20130101) H01L 29/1608 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541346 | Antunez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Priscilla D. Antunez (Tarrytown, New York); Douglas M. Bishop (New York, New York); Gloria W. Fraczak (Bellerose, New York); Oki Gunawan (Westwood, New Jersey); Richard A. Haight (Mahopac, New York) |
| ABSTRACT | Improved high work function back contacts for solar cells are provided. In one aspect, a method of forming a solar cell includes: forming a completed solar cell having a substrate coated with an electrically conductive material, an absorber disposed on the electrically conductive material, a buffer layer disposed on the absorber, a transparent front contact disposed on the buffer layer, and a metal grid disposed on the transparent front contact; removing the substrate and the electrically conductive material using exfoliation, exposing a backside surface of the solar cell; depositing a high work function material onto the back side surface of the solar cell; and depositing a back contact onto the high work function material. A solar cell formed by the present techniques is also provided. Yield of the exfoliated device can be improved by removing bubbles from adhesive used for exfoliation and/or forming contact pads to access the metal grid. |
| FILED | Monday, February 06, 2017 |
| APPL NO | 15/425717 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/072 (20130101) Original (OR) Class H01L 31/0326 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541429 | Roeder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jeffrey F. Roeder (Newtown, Connecticut); Peter C. Van Buskirk (Brookfield, Connecticut) |
| ASSIGNEE(S) | Sonata Scientific LLC (Bethel, Connecticut) |
| INVENTOR(S) | Jeffrey F. Roeder (Newtown, Connecticut); Peter C. Van Buskirk (Brookfield, Connecticut) |
| ABSTRACT | A novel method to produce thin films spatially disposed on desired areas of workpieces is disclosed. Examples of include the formation of a yttria stabilized zirconia (YSZ) film formed on a desired portion of a stainless steel interconnect for solid oxide fuel cells by Atomic Layer Deposition (ALD). A number of methods to produce the spatially disposed YSZ film structures are described including polymeric and silicone rubber masks. The thin film structures have utility for preventing the reaction of glasses with metals, in particular alkali-earth containing glasses with ferritic stainless steels, allowing high temperature bonding of these materials. |
| FILED | Sunday, October 22, 2017 |
| APPL NO | 15/790023 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/021 (20130101) Original (OR) Class H01M 8/0215 (20130101) H01M 8/0228 (20130101) H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541586 | Post |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Richard F Post (Walnut Creek, California) |
| ABSTRACT | Robust electro-static (ES) device embodiments, with application to energy storage flywheels as an example, are described that provide reliable, high-efficiency operation in the presence of thermal and mechanical perturbations, as well as seismic events. Electro-static generators and motors, when augmented with magnetic bearings, passive three-dimensional stabilization techniques and dynamic touch-down bearings, enable robust performance in the face of these environmental concerns, as well as efficient operation during typical operational sequences, including spin-up and steady-state modalities. |
| FILED | Tuesday, July 05, 2016 |
| APPL NO | 15/202446 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 7/025 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 1/00 (20130101) H02N 1/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541611 | Giuliano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David M. Giuliano (Cambridge, Massachusetts); David J. Perreault (Cambridge, Massachusetts); Robert C. N. Pilawa-Podgurski (Cambridge, Massachusetts) |
| ABSTRACT | A converter circuit and related technique for providing high power density power conversion includes a reconfigurable switched capacitor transformation stage coupled to a magnetic converter (or regulation) stage. The circuits and techniques achieve high performance over a wide input voltage range or a wide output voltage range. The converter can be used, for example, to power logic devices in portable battery operated devices. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/146028 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/07 (20130101) H02M 3/155 (20130101) H02M 3/158 (20130101) Original (OR) Class H02M 2001/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541660 | McKisson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
| ASSIGNEE(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
| INVENTOR(S) | John E. McKisson (Williamsburg, Virginia) |
| ABSTRACT | A passive bias temperature compensation module for silicon photomultiplier, avalanche photodiodes and similar photodetectors that possess a moderately linear temperature coefficient of gain and that may be compensated by varying an applied bias voltage. The module includes an electrical circuit and a method for determining component values to provide a constant voltage source to stabilize the gain of one or more photodetector devices. A temperature sensor in the module is held in close thermal contact with the photodetector and a filter capacitor is electrically close to the photodetector. The module is based on the concept of temperature sensitive voltage division which is applicable to situations in which large numbers of photodetectors must be gain-compensated for temperature variations over a wide range while maintaining excellent gain matching. The passive bias temperature compensation method enables multiple photodetectors to share a single constant voltage supply without loss of matching performance. |
| FILED | Tuesday, October 24, 2017 |
| APPL NO | 15/792437 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) G01J 2001/444 (20130101) Resistors H01C 7/008 (20130101) Control of Amplification H03G 1/0041 (20130101) H03G 3/20 (20130101) Original (OR) Class H03G 3/3084 (20130101) H03G 2201/708 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/185 (20130101) H05K 1/186 (20130101) H05K 3/30 (20130101) H05K 2201/1006 (20130101) H05K 2201/10015 (20130101) H05K 2201/10022 (20130101) H05K 2201/10151 (20130101) H05K 2201/10219 (20130101) H05K 2201/10515 (20130101) H05K 2201/10522 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541996 | Choi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Sung Nam Choi (Sandia Park, New Mexico); David John Zage (Fremont, California); Tam Dang Le (Rio Rancho, New Mexico); Susan L. Washburn (Albuquerque, New Mexico) |
| ABSTRACT | Systems and methods are disclosed that provide for secure communications between a user device and an authentication system. The systems and methods create a dynamic identification for the device that is stored in both the device and authentication system. |
| FILED | Wednesday, June 15, 2016 |
| APPL NO | 15/183454 |
| ART UNIT | 2493 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/083 (20130101) H04L 63/0823 (20130101) H04L 63/0853 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10542589 | Rios et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Orlando Rios (Knoxville, Tennessee); William G. Carter (Oak Ridge, Tennessee); Zachary C. Sims (Johnson City, Tennessee) |
| ABSTRACT | A method and apparatus for additive manufacturing that includes a material guide for directing a supply of working material. An advancement mechanism comprising one or more pistons, pushers, plungers and/or pressure regulation systems are positioned behind at least a portion of the supply of working material for advancing the working material forward. The working material is heated using an electro-magnetic heating element and the melted or molten working material is deposited from a tip positioned at an end of the material guide. |
| FILED | Tuesday, April 11, 2017 |
| APPL NO | 15/484937 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 23/005 (20130101) B21C 29/04 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 13/01 (20130101) B23K 13/04 (20130101) B23K 2103/10 (20180801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/16 (20130101) B29K 2105/0067 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/06 (20130101) H05B 6/14 (20130101) H05B 6/36 (20130101) H05B 6/40 (20130101) H05B 6/101 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10537283 | Caputo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Joshua M. Caputo (Pittsburgh, Pennsylvania); Steven H. Collins (Pittsburgh, Pennsylvania); Peter G. Adamcyzk (Ann Arbor, Michigan); Myunghee Kim (Pittsburgh, Pennsylvania); Tianjian Chen (Pittsburgh, Pennsylvania); Tianyao Chen (Washington, District of Columbia) |
| ABSTRACT | The present invention includes two embodiments of a tethered ankle-foot prosthesis, one with a single toe to provide plantarflexion and with two independently-actuated toes that are coordinated to provide plantarflexion and inversion-eversion torques. An end-effector was designed which is worn by a subject, and which was integrated with existing off-board motor and control hardware, to facilitate high bandwidth torque control. The platform is suitable for haptic rendering of virtual devices in experiments with humans, which may reveal strategies for improving balance or allow controlled comparisons of conventional prosthesis features. A similar morphology is also effective for autonomous devices. |
| FILED | Saturday, August 15, 2015 |
| APPL NO | 14/827299 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/08 (20130101) A61B 5/4851 (20130101) Original (OR) Class A61B 5/6811 (20130101) A61B 5/14542 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/66 (20130101) A61F 2/5046 (20130101) A61F 2/6607 (20130101) A61F 2002/503 (20130101) A61F 2002/701 (20130101) A61F 2002/704 (20130101) A61F 2002/763 (20130101) A61F 2002/6657 (20130101) A61F 2002/7625 (20130101) A61F 2002/7635 (20130101) A61F 2002/7645 (20130101) A61F 2002/7675 (20130101) A61F 2002/7695 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537403 | Vora et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Shrenik Vora (Philadelphia, Pennsylvania); Timothy Kurzweg (Philadelphia, Pennsylvania) |
| ABSTRACT | A wearable, wireless and battery-free continuous health monitor includes an RFID tag used as an On-Off Keying Device to measure the heart rate. The tag's returned signal strength variations are used to calculate the respiration rate. Machine learning algorithms are employed to determine the health parameters. |
| FILED | Monday, May 23, 2016 |
| APPL NO | 15/162544 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/0245 (20130101) A61B 5/0456 (20130101) A61B 5/0816 (20130101) A61B 90/98 (20160201) Original (OR) Class A61B 2503/04 (20130101) A61B 2560/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537733 | Dixon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Warren Dixon (Gainesville, Florida); Matthew J. Bellman (Gainesville, Florida) |
| ABSTRACT | Functional electrical stimulation (FES) cycling devices and associated methods are generally described. An FES cycling device may comprise a crank, two or more pedals connected to the crank, one or more sensors adapted to measure position and/or velocity of the crank, and one or more electrodes configured to deliver electrical stimulation to a person associated with the cycling device. In some cases, the FES cycling device further comprises a controller configured to receive input signals from the one or more sensors and deliver output signals to the one or more electrodes. In certain cases, the controller may dynamically generate a control signal to deliver an amount of electrical stimulation to a muscle group (e.g., quadriceps femoris, gluteal muscles, hamstring muscles) based on the value of a determined torque transfer ratio between a joint of the person and the crank of the cycling device. The electrical stimulation may, in some cases, cause the person to pedal the cycling device. |
| FILED | Friday, June 05, 2015 |
| APPL NO | 15/308541 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0452 (20130101) A61N 1/0484 (20130101) A61N 1/36003 (20130101) Original (OR) Class A61N 1/36014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537860 | Anand et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Sushant Anand (Somerville, Massachusetts); Seyed Reza Mahmoudi (Waltham, Massachusetts); Ingrid Fuller Guha (Cambridge, Massachusetts); Kripa Kiran Varanasi (Lexington, Massachusetts) |
| ABSTRACT | Nanoscale emulsions can be made by means of condensing a liquid vapor onto another liquid. The precise size, chemical composition, and density of emulsions may be controlled through varying the experimental parameters, such as surfactant concentration, time of condensation, humidity, and temperature. |
| FILED | Tuesday, June 23, 2015 |
| APPL NO | 15/318349 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/107 (20130101) A61K 9/1075 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0811 (20130101) Original (OR) Class B01F 17/00 (20130101) B01F 2003/0823 (20130101) B01F 2003/0838 (20130101) B01F 2003/0842 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538028 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | John A. Rogers (Champaign, Illinois); Sheng Xu (Urbana, Illinois); Zheng Yan (Urbana, Illinois); Yihui Zhang (Evanston, Illinois); Yonggang Huang (Glencoe, Illinois) |
| ABSTRACT | Origami- and Kirigami-inspired assembly of predetermined three-dimensional forms is presented in comprehensive theoretical and experimental studies, with examples of a broad range of topologies and material compositions. The resulting engineering options in the construction of functional 3D structures have important implications for advanced microsystem technologies. |
| FILED | Tuesday, November 17, 2015 |
| APPL NO | 14/944039 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 61/006 (20130101) B29C 61/0616 (20130101) Original (OR) Class Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/756 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/00 (20130101) B32B 27/40 (20130101) B32B 27/283 (20130101) B32B 27/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538431 | Barsoum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Michel W. Barsoum (Moorestown, New Jersey); Chunfeng Hu (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention is directed to crystalline solids having an empirical formula of M2A2X, wherein M is at least one Group IIIB, IVB, VB, or VIB metal, preferably Cr, Hf, Sc, Ti, Mo, Nb, Ta, V, Zr, or a combination thereof; wherein A is Al, Ga, Ge, In, Pb, or Sn, or a combination thereof; and each X is CxNy, where x+y=1. In some particular embodiments, the crystalline composition has a unit cell stoichiometry of Mo2Ga2C. |
| FILED | Tuesday, March 01, 2016 |
| APPL NO | 15/554904 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/062 (20130101) C01B 21/072 (20130101) C01B 21/076 (20130101) C01B 21/0602 (20130101) Original (OR) Class C01B 21/0605 (20130101) C01B 21/0617 (20130101) C01B 21/0632 (20130101) C01B 32/90 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538570 | Leonard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Joshua N. Leonard (Wilmette, Illinois); Michelle E. Hung (Chicago, Illinois) |
| ABSTRACT | Disclosed are exosomes that include a packaging protein and a cargo RNA in which the packaging protein binds specifically to the cargo RNA. The packaging protein is a fusion protein that includes an RNA-binding domain and an exosome-targeting domain. The cargo RNA includes an RNA-motif that the RNA-binding domain of the fusion protein binds specifically such that the cargo RNA is packaged in the lumen of the exosomes. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 14/502494 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 2319/85 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538636 | Pugh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Coleen Pugh (Akron, Ohio); Ajay Ramesh Amrutkar (Akron, Ohio) |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Coleen Pugh (Akron, Ohio); Ajay Ramesh Amrutkar (Akron, Ohio) |
| ABSTRACT | Specific benzocyclobutenes serve as intramolecular or intermolecular or both intramolecular or intermolecular crosslinkers. The benzocyclobutenes can be incorporated into polymers post polymerization or can be provided as monomers that participate in homopolymerization or copolymerization with other monomer to create the polymers having benzocyclobutenes that are exploited to carry out the crosslinking. At least some of the benzocyclobutenes taught herein can be used to carry out crosslinking a ambient temperatures. |
| FILED | Monday, October 09, 2017 |
| APPL NO | 15/728053 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 69/157 (20130101) C07C 2602/06 (20170501) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 12/22 (20130101) C08F 212/08 (20130101) C08F 212/14 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) Original (OR) Class C08J 2325/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538773 | Park et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Hee-Sung Park (Daejeon, South Korea); Dieter Soll (Guilford, Connecticut) |
| ABSTRACT | Nucleic acids encoding mutant elongation factor proteins (EF-Sep), phosphoseryl-tRNA synthetase (SepRS), and phosphoseryl-tRNA (tRNASep) and methods of use in site specific incorporation of phosphoserine into a protein or polypeptide are described. Mutant EF-Sep proteins are disclosed that bind Sep-tRNASep and protect Sep-tRNASep from deacylation. In a preferred embodiment the nucleic acids are on vectors and are expressed in cells such as bacterial cells, archeaebacterial cells, and eukaryotic cells. Proteins or polypeptides containing phosphoserine produced by the methods described herein can be used for a variety of applications such as research, antibody production, protein array manufacture and development of cell-based screens for new drug discovery. |
| FILED | Wednesday, February 22, 2017 |
| APPL NO | 15/439449 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/245 (20130101) C07K 14/435 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) C12N 15/67 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) C12P 21/02 (20130101) Enzymes C12Y 601/01027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538887 | Thrall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana); HNTB Corporation (New York, New York) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana); HNTB Corporation (New York, New York) |
| INVENTOR(S) | Ashley P. Thrall (South Bend, Indiana); Mirela D. Tumbeva (Notre Dame, Indiana); Theodore P. Zoli, III (New York, New York) |
| ABSTRACT | An adjustable structural connection—a connection which can be adjusted to alter the location and angle of member attachment—transforms the traditional notion of connections as a static means of connecting members at specific angles to a dynamic means of assembling a variety of structurally efficient forms. The adjustable connection connects a diagonal member to a vertical or horizontal member using either curved plate mounted to both of the structural members or a temporarily rotatable link. The adjustable connection can be used in a kit-of-parts type system, using multiple versions of the adjustable connection, which can join members at a wide variety of angles using a small number of unique components. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 15/610414 |
| ART UNIT | 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Construction of Bridges, or Viaducts; Assembly of Bridges E01D 4/00 (20130101) E01D 6/00 (20130101) Original (OR) Class E01D 15/133 (20130101) Structural Elements; Building Materials E04C 3/08 (20130101) E04C 3/40 (20130101) E04C 2003/0491 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539346 | Coppola et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Anthony Coppola (Urbana, Illinois); Scott R. White (Champaign, Illinois); Nancy R. Sottos (Champaign, Illinois) |
| ABSTRACT | Autonomic cooling of a substrate is achieved using a porous thermal protective layer to provide evaporative cooling combined with capillary pumping. The porous thermal protective layer is manufactured onto the substrate. A vascular network is integrated between the substrate and the protective layer. Applied heat causes fluid contained in the protective layer to evaporate, removing heat. The fluid lost to evaporation is replaced by capillary pressure, pulling fluid from a fluid-containing reservoir through the vascular network. Cooling occurs as liquid evaporates from the protective layer. |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/274591 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 7/004 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/024 (20130101) B32B 5/26 (20130101) B32B 7/12 (20130101) B32B 9/005 (20130101) B32B 9/041 (20130101) B32B 9/045 (20130101) B32B 9/047 (20130101) B32B 15/00 (20130101) B32B 15/01 (20130101) B32B 15/08 (20130101) B32B 15/14 (20130101) B32B 15/18 (20130101) B32B 15/20 (20130101) B32B 18/00 (20130101) B32B 27/06 (20130101) B32B 27/08 (20130101) B32B 27/12 (20130101) B32B 2250/02 (20130101) B32B 2260/023 (20130101) B32B 2260/046 (20130101) B32B 2262/101 (20130101) B32B 2262/106 (20130101) B32B 2307/50 (20130101) B32B 2307/306 (20130101) B32B 2307/732 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 19/00 (20130101) Original (OR) Class Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539508 | Suslick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Kenneth S. Suslick (Champaign, Illinois); Jon R. Askim (Urbana, Illinois) |
| ABSTRACT | A portable device for colorimetric or fluorometric analysis comprises a linear array of optically-responsive chemical sensing elements; an image sensor in optical communication with the linear array for determining a spectral response of the optically-responsive chemical sensing elements, where the image sensor comprises at least one light emission source; and electronics connected to the image sensor for analyzing spectral response data. A method of conducting colorimetric or fluorometric analysis comprises exposing a linear array of optically-responsive chemical sensing elements to a fluid comprising an analyte; impinging light on the linear array and detecting a spectral response of the chemical sensing elements; and determining an exposed color of each of the chemical sensing elements. |
| FILED | Tuesday, June 09, 2015 |
| APPL NO | 15/317840 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Original (OR) Class G01N 21/80 (20130101) G01N 2021/7773 (20130101) G01N 2021/7786 (20130101) G01N 2021/7793 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539621 | Chow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TOTAL SOLAR INTERNATIONAL (Courbevoie, France); NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| ASSIGNEE(S) | TOTAL SOLAR INTERNATIONAL (Courbevoie, France); NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| INVENTOR(S) | Mo-Yuen Chow (Cary, North Carolina); Bharat Balagopal (Raleigh, North Carolina); Wente Zeng (Cary, North Carolina) |
| ABSTRACT | A method, an apparatus, and a system for determining a state of a battery are provided. The method includes acquiring battery information from a sensor associated with the battery. The battery information includes at least terminal voltage and a terminal current. The method further includes estimating degradation information based on a first principle degradation model and the battery information. The first principle degradation model is a three dimensional model that includes a plurality of layers having one or more attributes representative of physical parameters of the battery. The method further includes identifying a circuit model based on the degradation information and the battery information, determining the state of the battery using the identified circuit model, and implementing a control action or a notification based on the determined state of the battery. |
| FILED | Wednesday, August 02, 2017 |
| APPL NO | 15/667103 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/392 (20190101) G01R 31/3646 (20190101) G01R 31/3648 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540083 | Goel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Mayank Goel (Seattle, Washington); Jacob O. Wobbrock (Seattle, Washington); Shwetak N. Patel (Seattle, Washington); Leah Findlater (Hyattsville, Maryland) |
| ABSTRACT | A system for classifying a user touch event by a user interacting with a device as an intended key is provided. For different hand postures (e.g., holding device with right hand and entering text with right thumb), the system provides a touch pattern model indicating how the user interacts using that hand posture. The system receives an indication of a user touch event and identifies the hand posture of the user. The system then determines the intended key based on the user touch event and a touch pattern model for the identified hand posture. A system is also provided for determining the amount a presser a user is applying to the device based on dampening of vibrations as measured by an inertial sensor. A system is provided that uses motion of the device as measured by an inertial sensor to improve the accuracy of text entry. |
| FILED | Wednesday, December 11, 2013 |
| APPL NO | 14/646528 |
| ART UNIT | 2626 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0416 (20130101) G06F 3/0488 (20130101) Original (OR) Class G06F 3/04886 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10540782 | Benini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado Seminary Which Owns and Operates the University of Denver (Denver, Colorado) |
| ASSIGNEE(S) | Colorado Seminary Which Owns and Operates the University of Denver (Denver, Colorado) |
| INVENTOR(S) | Alessandro Benini (Denver, Colorado); Matthew J. Rutherford (Denver, Colorado); Kimon P. Valavanis (Denver, Colorado) |
| ABSTRACT | A method for estimating a pose of a first object in relation to a second object, the second object comprising a visual marker comprising a plurality of ellipses comprises capturing a video image of the visual marker with an image capture device on the first object, then pre-processing frames of the video image on a graphics processing unit. The method comprises detecting the visual marker by finding contours in the frames to identify the plurality of ellipses and determining that a pattern of the plurality of ellipses match a known pattern of the visual marker. Then the method comprises obtaining coordinates of two or more of the plurality of ellipses of the visual marker, estimating the pose of the first object in relation to the second object by inputting the coordinates of the plurality of ellipses into a pose estimation algorithm, and filtering results of the pose estimation algorithm. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 15/814232 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 1/20 (20130101) G06T 7/13 (20170101) G06T 7/60 (20130101) G06T 7/73 (20170101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/10032 (20130101) G06T 2207/30204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541136 | Mazur et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Eric Mazur (Concord, Massachusetts); Michael J. Aziz (Concord, Massachusetts); Hemant Gandhi (Cambridge, Massachusetts); David Pastor (Cambridge, Massachusetts) |
| ABSTRACT | In one aspect a method of fabricating an n-doped strained germanium (Ge) film is disclosed, which includes depositing a strained Ge film on an underlying substrate, implanting at least one electron-donating dopant in the Ge film, and exposing the implanted Ge film to one or more laser pulses having a pulsewidth in a range of about 1 ns to about 100 ms so as to generate a substantially crystalline strained Ge film. In some embodiments, the pulses can cause melting followed by substantial recrystallization of at least a portion of the implanted Ge film. In some embodiments, the resultant Ge film can have a thickness in a range of about 10 nm to about 1 microns. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 15/825398 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/352 (20151001) B23K 26/0622 (20151001) B23K 26/0643 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/268 (20130101) H01L 21/324 (20130101) H01L 21/02381 (20130101) H01L 21/02395 (20130101) H01L 21/02422 (20130101) H01L 21/02532 (20130101) H01L 21/02686 (20130101) Original (OR) Class H01L 21/26513 (20130101) H01L 21/67115 (20130101) H01L 29/36 (20130101) H01L 29/167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541601 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Shuo Wang (Gainesville, Florida); Hui Zhao (Cambridge, United Kingdom); Le Yang (Gainesville, Florida) |
| ABSTRACT | Various examples related to electromagnetic interference (EMI) energy mitigation techniques are provided. In one example, a method includes adjusting switching angles of a switching circuit based on resolution bandwidths (RBWs) associated with an EMI frequency spectrum of the switching circuit and weight coefficients of the RBWs. The total energy of the switching circuit can be reduced by adjusting an average duty cycle of the switching circuit. EMI spectrum information can be determined based upon switching angles of a switching circuit. For example, weighted errors corresponding to differences between reference harmonic magnitudes and determined harmonic magnitudes can be determined. In response to a comparison of a maximum weighted error to a preset tolerance threshold, adjustment to the switching angles can be determined and/or applied. |
| FILED | Tuesday, October 30, 2018 |
| APPL NO | 16/175219 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 23/20 (20130101) G01R 31/002 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/44 (20130101) Original (OR) Class H02M 7/5395 (20130101) H02M 7/53875 (20130101) Pulse Technique H03K 7/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541661 | Fok et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Mable P. Fok (Bishop, Georgia); Jia Ge (Athens, Georgia) |
| ABSTRACT | Various examples are provided for highly reconfigurable multiband radio frequency (RF) filters. The multiband RF filters can be continuously tunable. In one example, a multiband RF filter includes a Lyot loop filter that can generate an optical comb using an input optical signal from a tunable Mach-Zehnder interferometer (MZI), a birefringent device, and a polarization rotation angle of a polarization controller. The tunable MZI can include a tunable delay line that can adjust comb spacing of the optical comb. In another example, a multiband RF filter includes a second MZI in series with a first MZI. The second MZI can generate a second tunable output signal from a first tunable output signal from the first MZI. In another example, the multiband RF filter can include a third MZI in series with the second MZI. The third MZI can generate a third tunable output signal from the second tunable output signal. |
| FILED | Thursday, August 17, 2017 |
| APPL NO | 15/679280 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/29302 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/225 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 2/003 (20130101) Original (OR) Class H03H 2250/00 (20130101) Transmission H04B 2210/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541803 | Prvulovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Milos Prvulovic (Atlanta, Georgia); Nina Basta (Atlanta, Georgia); Robert Callan (Atlanta, Georgia); Alenka Zajic (Atlanta, Georgia) |
| ABSTRACT | Aspects of the disclosed technology provide a method comprising executing different first and second instructions a first and second number of times, respectively, in repeated alternations. The method further comprises measuring spectra of signals emanating as a result of the processor executing the first and second instructions. The method also includes analyzing data indicative of the spectra of the signals to determine side-channel candidate side-band pairs that each have a lower and upper sideband at first and second frequencies, respectively, that are separated by approximately twice the respective alternation frequency. Finally, the method includes identifying a side-channel carrier frequency at a frequency approximately at a midpoint between a side-channel candidate side-band pair's first and second frequency. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/023838 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/003 (20130101) Original (OR) Class H04L 2209/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541843 | Wentzloff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | David D. Wentzloff (Ann Arbor, Michigan); Hun-Seok Kim (Ann Arbor, Michigan); Jaeho Im (Ann Arbor, Michigan) |
| ABSTRACT | An ultra-low power back-channel receiver is presented that demodulates binary a FSK back-channel signal embedded in 5.8 GHz IEEE 802.11a Wi-Fi OFDM packets. The architecture of the back-channel receiver employs a two-step down-conversion where the first mixing stage downconverts using the third harmonic of the local oscillator for power efficiency. The LP-65 nm CMOS receiver consumes 335 μW with a sensitivity of −72 dBm at a BER of 10−3 and data-rate of 31.25 kb/s. The radio uses a balun and a 250 kHz reference crystal as external components. The receiver uses a 1V supply voltage for analog blocks, and 0.85V for digital blocks including the local oscillator and the frequency-locked loop circuits. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 15/919510 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/0078 (20130101) H04B 1/406 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0007 (20130101) H04L 27/1525 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10537275 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Quan Zhang (Winchester, Massachusetts); Gary Strangman (Boxford, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Quan Zhang (Winchester, Massachusetts); Gary Strangman (Boxford, Massachusetts) |
| ABSTRACT | A system and a method is provided for assessing motion of a biological tissue of a subject including one or more superficial biological layers and a targeted biological layer. An optical perturbation is introduced within the one or more superficial biological layers but not within the targeted biological layer. A set of optical signal data is acquired preceding, during, or following the optical perturbation and, using the set of optical signal data, a set of optical characteristics is determined that is representative of light transiting the biological layers. Using the set of optical characteristics and a model of the biological layers, a target optical signal consistent with a target biological layer is separated and a movement of the desired biological tissue is determined using the target optical signal. |
| FILED | Wednesday, June 25, 2014 |
| APPL NO | 14/900840 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/4064 (20130101) Original (OR) Class A61B 5/6814 (20130101) A61B 5/14553 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538321 | North et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | David D. North (Williamsburg, Virginia); Mark J. Aull (Cincinatti, Ohio); William J. Fredericks (Williamsburg, Virginia); Mark D. Moore (Williamsburg, Virginia); Paul M. Rothhaar (Newport News, Virginia); William T. Hodges (Yorktown, Virginia); Zachary R. Johns (Virgina Beach, Virginia) |
| ABSTRACT | Systems, methods, and devices provide a vehicle, such as an aircraft, with rotors configured to function as a tri-copter for vertical takeoff and landing (“VTOL”) and a fixed-wing vehicle for forward flight. One rotor may be mounted at a front of the vehicle fuselage on a hinged structure controlled by an actuator to tilt from horizontal to vertical positions. Two additional rotors may be mounted on the horizontal surface of the vehicle tail structure with rotor axes oriented vertically to the fuselage. For forward flight of the vehicle, the front rotor may be rotated down such that the front rotor axis may be oriented horizontally along the fuselage and the front rotor may act as a propeller. For vertical flight, the front rotor may be rotated up such that the front rotor axis may be oriented vertically to the fuselage, while the tail rotors may be activated. |
| FILED | Tuesday, September 11, 2018 |
| APPL NO | 16/127640 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 5/02 (20130101) B64C 25/52 (20130101) B64C 29/0025 (20130101) B64C 29/0033 (20130101) Original (OR) Class B64C 39/024 (20130101) B64C 2201/042 (20130101) B64C 2201/044 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/24 (20130101) B64D 2027/026 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/44 (20130101) Y02T 50/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10538345 | Ambrose et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Jay H. Ambrose (Saratoga, California); Rolland Holmes (Menlo Park, California) |
| ABSTRACT | A heat pipe has an evaporator portion, a condenser portion, and at least one flexible portion that is sealingly coupled between the evaporator portion and the condenser portion. The flexible portion has a flexible tube and a flexible separator plate held in place within the flexible tube so as to divide the flexible tube into a gas-phase passage and a liquid-phase artery. The separator plate and flexible tube are configured such that the flexible portion is flexible in a plane that is perpendicular to the separator plate. |
| FILED | Thursday, December 17, 2015 |
| APPL NO | 14/973540 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/503 (20130101) Original (OR) Class B64G 1/506 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/04 (20130101) F28D 15/046 (20130101) F28D 15/0241 (20130101) F28D 15/0275 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539667 | Peng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Han Peng (Niskayuna, New York); Juan Antonio Sabate (Niskayuna, New York); Kieran Andrew Wall (Moss, Norway) |
| ABSTRACT | An ultrasound pulse generator circuit includes a first gate driver electrically coupled to a first gallium nitride (GaN) transistor, a second gate driver electrically coupled to a second GaN transistor, a first snubber circuit, a second snubber circuit, and a transformer. The first snubber circuit and the second snubber circuit each include a respective capacitor and resistor and each snubber circuit is configured to clamp a voltage overshoot when present. Further, the transformer generates an output signal when operated and the third transformer is electrically connected downstream of the first GaN transistor, the second GaN transistor, the first snubber circuit, and the second snubber circuit. In addition, the transformer includes multiple windings. |
| FILED | Friday, January 06, 2017 |
| APPL NO | 15/400807 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/4483 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/5202 (20130101) Original (OR) Class G01S 7/52085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541266 | Greer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Frank Greer (Pasadena, California); Todd J. Jones (Altadena, California); Shouleh Nikzad (Valencia, California); Michael E. Hoenk (Valencia, California) |
| ABSTRACT | High-quality surface coatings, and techniques combining the atomic precision of molecular beam epitaxy and atomic layer deposition, to fabricate such high-quality surface coatings are provided. The coatings made in accordance with the techniques set forth by the invention are shown to be capable of forming silicon CCD detectors that demonstrate world record detector quantum efficiency (>50%) in the near and far ultraviolet (155 nm-300 nm). The surface engineering approaches used demonstrate the robustness of detector performance that is obtained by achieving atomic level precision at all steps in the coating fabrication process. As proof of concept, the characterization, materials, and exemplary devices produced are presented along with a comparison to other approaches. |
| FILED | Tuesday, August 18, 2015 |
| APPL NO | 14/829238 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1462 (20130101) H01L 27/1464 (20130101) H01L 27/14685 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10537274 | Damaser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Margot Damaser (Cleveland Heights, Ohio); Hassan K. Awada (Pittsburgh, Pennsylvania); Paul C. Fletter (Mt. Prospect, Illinois); Mitchell Cooper (Ithaca, New York); Paul Zaszczurynski (Sycamore, Illinois) |
| ASSIGNEE(S) | THE U.S. GOVT AS REPRESENTED BY THE DEPT. OF VETERANS AFFAIRS (Washington, District of Columbia); THE CLEVELAND CLININC FOUNDATION (Cleveland, Ohio) |
| INVENTOR(S) | Margot Damaser (Cleveland Heights, Ohio); Hassan K. Awada (Pittsburgh, Pennsylvania); Paul C. Fletter (Mt. Prospect, Illinois); Mitchell Cooper (Ithaca, New York); Paul Zaszczurynski (Sycamore, Illinois) |
| ABSTRACT | Systems and methods are provided for providing a standardized pressure value representing a transient pressure event within a region of interest within a living body. An air-charged catheter is configured to record pressure data representing the region of interest. A measurement assembly includes a parameter calculation component configured to calculate at least a peak pressure representing the transient pressure event and a time to peak pressure, representing the time necessary to reach the peak pressure, from the recorded pressure data. A standardization component is configured to calculate the standardized pressure value as a function of the peak pressure and the time to peak pressure. A user interface is configured to display at least the standardized pressure value at an associated display. |
| FILED | Friday, September 21, 2012 |
| APPL NO | 13/623981 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/036 (20130101) A61B 5/205 (20130101) Original (OR) Class A61B 5/742 (20130101) A61B 5/0823 (20130101) A61B 5/7278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537577 | Boden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); The United States Government as represented by the Department of Veterans Affairs (Atlanta, Georgia) |
| INVENTOR(S) | Scott D. Boden (Atlanta, Georgia); Sreedhara Sangadala (Atlanta, Georgia) |
| ABSTRACT | The disclosure relates to compounds and compositions for forming bone and methods related thereto. In one embodiment, the disclosure relates to a composition comprising a compound disclosed herein, such as 2,4-diamino-1,3,5-triazine derivatives or salts thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement. |
| FILED | Thursday, November 02, 2017 |
| APPL NO | 15/801964 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) Original (OR) Class A61K 31/53 (20130101) A61K 38/1875 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 2300/412 (20130101) A61L 2430/02 (20130101) Heterocyclic Compounds C07D 251/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537609 | Lillehoj et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Erik P. Lillehoj (West Friendship, Maryland); Avelino C. Verceles (Elkridge, Maryland); Simeon E. Goldblum (Baltimore, Maryland) |
| ABSTRACT | Pseudomonas aeruginosa flagellin protein recruits the mammalian host sialidase enzyme neuraminidase-1 (NEU1) to remove sialic acid residues from the extracellular domain of the mammalian cell-surface protein MUC1 (MUC1-ED), thereby exposing a cryptic binding site on the MUC1-ED protein backbone for flagellin binding. NEU1-driven MUC1-ED desialylation rapidly increases P. aeruginosa adhesion to the airway epithelium. MUC1-ED desialylation also increases MUC1-ED cleavage and shedding from the cell surface, where desialylated, shed MUC1-ED competitively blocks P. aeruginosa adhesion to cell-associated MUC1-ED. Presented herein are data showing that exogenously-administered, deglycosylated MUC1-ED peptides reduced adhesion of P. aeruginosa to airway epithelial cells. Also presented are data showing that administration of P. aeruginosa to mice in combination with deglycosylated MUC1-ED decreased P. aeruginosa recovered from the lungs at 48 hr and 72 hr post-infection. Such findings are extended to the methods of treatment and prevention of bacterial infections defined herein. |
| FILED | Thursday, June 22, 2017 |
| APPL NO | 15/630165 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/546 (20130101) A61K 38/00 (20130101) A61K 38/1735 (20130101) Original (OR) Class Peptides C07K 14/4727 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 33/56916 (20130101) G01N 2333/21 (20130101) G01N 2333/195 (20130101) G01N 2333/245 (20130101) G01N 2333/4725 (20130101) Technologies for Adaptation to Climate Change Y02A 50/47 (20180101) Y02A 50/473 (20180101) Y02A 50/478 (20180101) Y02A 50/481 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10537089 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri); Heartland Farm Energy LLC (Boonville, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri); Heartland Farm Energy LLC (Boonville, Missouri) |
| INVENTOR(S) | Tingsheng Xu (Columbia, Missouri); Yunsheng Xu (Columbia, Missouri) |
| ABSTRACT | A system and method for thermally exchanging heat between waste air being expelled from a poultry barn and fresh outside/outdoor ambient air being introduced into the poultry barn. |
| FILED | Wednesday, November 16, 2016 |
| APPL NO | 15/353192 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 1/0076 (20130101) Original (OR) Class Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 7/1623 (20130101) F28D 21/0014 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 9/26 (20130101) F28F 9/187 (20130101) F28F 21/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10537125 | Annous et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); Rutgers University (New Brunswick, New Jersey) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Bassam A Annous (North Wales, Pennsylvania); Carol Saade (Battle Creek, Michigan); Kit L. Yam (New Brunswick, New Jersey) |
| ABSTRACT | Disclosed herein are chlorine dioxide releasing package label/inserts to be used inside a package or in an outer plastic bag containing several individual packages, the package label/insert containing (a) at least one layer of pectin and citric acid, (b) at least one layer of gelatin and sodium chlorite, (c) optionally at least one barrier layer containing gelatin (without sodium chlorite) between the at least one layer of pectin and citric acid and the at least one layer of gelatin and sodium chlorite, and (d) an adhesive joining said layers, wherein the package label/insert has alternating layers of the at least one layer of pectin and citric acid and the at least one layer of gelatin and sodium chlorite. Also disclosed are methods of killing microorganisms on an item using the package label/insert described herein. |
| FILED | Tuesday, May 23, 2017 |
| APPL NO | 15/602263 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 3/349 (20130101) Original (OR) Class Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 81/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10538861 | Shah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Radiation Monitoring Devices, Inc. (Watertown, Massachusetts) |
| ASSIGNEE(S) | Radiation Monitoring Devices, Inc. (Watertown, Massachusetts) |
| INVENTOR(S) | Kanai S. Shah (Watertown, Massachusetts); Josh Tower (Natick, Massachusetts); Rastgo Hawrami (Watertown, Massachusetts) |
| ABSTRACT | Disclosed embodiments are related to a method of forming an elpasolite scintillator. In one nonlimiting embodiment, a method of forming an elpasolite scinitillator may comprise forming an elpasolite crystal from a nonstoichiometric melt. |
| FILED | Thursday, January 29, 2015 |
| APPL NO | 14/608665 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/77 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 11/02 (20130101) C30B 13/16 (20130101) C30B 15/00 (20130101) C30B 29/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539707 | Barela et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Cecilia Barela (Washington, District of Columbia); Tye McGrath (Washington, District of Columbia) |
| ABSTRACT | Various embodiments of the present invention are directed towards a system and method for synchronized markers. A multiple-scanner X-ray system includes a belt passing by an upper X-ray scanner and a lower X-ray scanner. An upper belt portion is conveyed in a first direction by the upper X-ray scanner and a lower belt portion is conveyed in a second direction opposite the first direction by the lower X-ray scanner, to obtain upper and lower X-rays. A plurality of X-ray reactive markers are positionally synchronized relative to each other and the belt and conveyed by the belt to cause upper visual marker information, corresponding to a visual appearance of the upper scanned belt section, to be consistent with i) upper X-ray marker information of the upper X-ray, and ii) lower X-ray marker information of the lower X-ray. |
| FILED | Friday, March 30, 2018 |
| APPL NO | 15/941657 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 49/00 (20130101) B65G 2201/0264 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) G01N 2223/303 (20130101) G01N 2223/417 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/0016 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10538549 | Hang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bo Hang (Lafayette, California); Ahmed Chenna (Sunnyvale, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bo Hang (Lafayette, California); Ahmed Chenna (Sunnyvale, California) |
| ABSTRACT | NNA-derived specific adducts represent an integrated biomarker of exposure to thirdhand smoke (THS) as NNA is unique to THS. The NNA-dG covalent binding adduct could serve as such a biomarker, and play a role in identifying individuals exposed to THS, thus providing critical information for early detection and prevention. |
| FILED | Monday, March 16, 2015 |
| APPL NO | 14/659588 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/16 (20130101) Original (OR) Class C07H 19/23 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10539530 | Tao |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nongjian Tao (Fountain Hills, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Nongjian Tao (Fountain Hills, Arizona) |
| ABSTRACT | A system for analyzing a content of a sample material is presented. The system includes a fiber sensitized to a first substance, and at least one electrode configured to expose the fiber to an electric field. The system includes an optical sensor configured to detect a displacement of the fiber when the fiber is exposed to the electric field, and a processor configured to use the displacement of the fiber to characterize a content of the sample material. |
| FILED | Tuesday, September 19, 2017 |
| APPL NO | 15/709032 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/60 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Central Intelligence Agency (CIA)
| US 10541814 | Leavy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wickr Inc. (San Francisco, California) |
| ASSIGNEE(S) | Wickr Inc. (Pleasanton, California) |
| INVENTOR(S) | Thomas Michael Leavy (River Edge, New Jersey); Joël Alwen (Vienna, Austria) |
| ABSTRACT | The present application describes a method, system, and non-transitory computer-readable medium for end-to-end encryption during a secure communication session. According to the present disclosure, a first device receives an invitation to a secure communication session. The invitation includes a token, which the first device transmits to the call initiating device. Next, the first device performs a three-way handshake with the call initiating device to negotiate a first encryption key and a second encryption key for the secure communication session. The first device encrypts first communication data using the first encryption key and transmits the encrypted first communication data to the call initiating device. |
| FILED | Wednesday, November 08, 2017 |
| APPL NO | 15/806468 |
| ART UNIT | 2495 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/14 (20130101) H04L 9/088 (20130101) H04L 9/0841 (20130101) H04L 9/3066 (20130101) H04L 9/3226 (20130101) Original (OR) Class H04L 63/0428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 10538804 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ANDE CORPORATION (Waltham, Massachusetts) |
| ASSIGNEE(S) | ANDE Corporation (Waltham, Massachusetts) |
| INVENTOR(S) | Eugene Tan (Arlington, Massachusetts); Richard F. Selden (Lincoln, Massachusetts); Rosemary S. Turingan (Stoneham, Massachusetts) |
| ABSTRACT | Described herein are methods and devices for nucleic acid quantification and, in particular, to microfluidic methods and devices for nucleic acid quantification. In certain embodiments methods of quantifying a target nucleic acid without the need for amplification are provided. The methods involve, in some embodiments, allowing a binding agent to become immobilized with respect to the target nucleic acid. In some cases, the binding agent comprises a signaling moiety that can be used to quantify the amount of target nucleic acid. In another aspect, the quantification can be carried out rapidly. For example, in certain embodiments, the quantification can be completed within 5 minutes. In yet another aspect, samples containing a low amount of target nucleic acid can be quantified. For instance, in some cases, samples containing less than 100 nanograms per microliter may be quantified. Also described are devices and kits for performing such methods, or the like. |
| FILED | Thursday, January 19, 2017 |
| APPL NO | 15/410399 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502715 (20130101) B01L 7/52 (20130101) B01L 2300/0627 (20130101) B01L 2300/0819 (20130101) B01L 2300/0877 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1017 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6818 (20130101) C12Q 1/6825 (20130101) Original (OR) Class C12Q 2563/107 (20130101) C12Q 2565/629 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10539148 | Hubbert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Corey L. Hubbert (Manchester, Connecticut); Peter V. Tomeo (Middletown, Connecticut) |
| ABSTRACT | A fan rotor, for an aircraft engine, including at least one blade root attachment lug, each blade root attachment lug including an attachment lug surface, wherein at least one cavity is disposed on each attachment lug surface. |
| FILED | Friday, September 05, 2014 |
| APPL NO | 15/028512 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/3053 (20130101) F01D 11/008 (20130101) Non-positive-displacement Pumps F04D 29/34 (20130101) Original (OR) Class F04D 29/329 (20130101) F04D 29/644 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10540569 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Yu Cheng (Ossining, New York); Sharathchandra U. Pankanti (Darlen, Connecticut); Nalini K. Ratha (White Plains, New York) |
| ABSTRACT | A face clustering system for video face clustering in a video sequence, the system including an inherent supervision summarization device configured to collect group-level supervision and instance level supervision within a same chunklet based on a user input of face images for a person, a discriminative projection learning device configured to embed group constraints of the group-level supervision into a transformed space, and configured to generate an embedding space from the original image feature space, and a clustering device, in the embedding space, configured to execute pair-wise based clustering to cluster the video images into different clusters with the instance level supervision collected by the inherent supervision summarization device. |
| FILED | Tuesday, October 24, 2017 |
| APPL NO | 15/791801 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00288 (20130101) G06K 9/00295 (20130101) G06K 9/00718 (20130101) G06K 9/6218 (20130101) Original (OR) Class G06K 9/6264 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 10537737 | Orhan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| INVENTOR(S) | Umut Orhan (Kirkland, Washington); Santosh Mathan (Seattle, Washington); Michael Pavel (Boston, Massachusetts) |
| ABSTRACT | An adaptive non-invasive alternating current brain stimulation system and method includes supplying transcranial alternating current stimulation (tACS) from a tACS source to a person, and receiving electroencephalogram (EEG) signals from EEG sensors disposed on the person, where the EEG signals including stimulation interference. The received EEG signals are processed using an adaptive model to estimate the stimulation interference in the EEG signals. The estimated stimulation interference is subtracted from the EEG signals to estimate neural oscillations of the person. The estimated neural oscillations are processed through an autoregressive model to generate predictions of future neural activity of the person and, based on the generated predictions, one or more electrical characteristics of the tACS being supplied to the person are varied to thereby modulate the neural oscillations of the person. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 15/919439 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0476 (20130101) A61B 5/04017 (20130101) A61B 5/4836 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0529 (20130101) A61N 1/36025 (20130101) A61N 1/36031 (20170801) Original (OR) Class A61N 1/37514 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10540603 | Naaman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ofer Naaman (Ellicott City, Maryland); Zachary Kyle Keane (Baltimore, Maryland); Micah John Atman Stoutimore (Kensington, Maryland); David George Ferguson (Takoma Park, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Ofer Naaman (Ellicott City, Maryland); Zachary Kyle Keane (Baltimore, Maryland); Micah John Atman Stoutimore (Kensington, Maryland); David George Ferguson (Takoma Park, Maryland) |
| ABSTRACT | Real-time reconfigurability of quantum object connectivity can be provided with one or more quantum routers that can each be configured as either or both of a single-pole double-throw switch and a cross-point switch. The quantum router includes variable-inductance coupling elements in RF-SQUIDs having inductors transformer-coupled to two control flux lines, one providing a static current and the other providing a dynamic current, the direction of which can be toggled to couple or uncouple quantum objects, such as qubits, based on the dynamic current direction to provide reconfigurable quantum routing. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/012543 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0358 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/15 (20130101) Transmission H04B 10/70 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 49/101 (20130101) Selecting H04Q 3/523 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10541688 | Knowles et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Kenneth R. Knowles (Manassas, Virginia); Daniel Pirkl (Centreville, Virginia) |
| ABSTRACT | A ring oscillator circuit is disclosed. The ring oscillator in one embodiment includes an odd number of inverters connected in a loop fashion, a current mirror having a drain of a first transistor connected to the inverters, and a self-biased inverter connected to a drain of a second transistor of the current mirror. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 15/832502 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 3/0315 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 1/022 (20130101) H03L 7/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, January 21, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200121.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page