FedInvent™ Patents
Patent Details for Tuesday, January 28, 2020
This page was updated on Monday, March 27, 2023 at 06:00 AM GMT
Department of Health and Human Services (HHS)
| US 10542927 | Furman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Neuro Kinetics, Inc. (Pittsburgh, Pennsylvania); University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | NEURO KINETICS, INC. (Pittsburgh, Pennsylvania); UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Joseph M Furman (Pittsburgh, Pennsylvania); Alexander D Kiderman (Pittsburgh, Pennsylvania); Ian A Shirey (Pittsburgh, Pennsylvania) |
| ABSTRACT | A system and associated method for computerized rotational head impulse test (crHIT) to assess the semicircular canals of the human vestibular system clinically in patients with balance disorders. The system utilizes a rotary chair combined with a head mounted VOG system with head tracking sensors. The crHIT protocol uses the same physiologic principles as the known video head impulse test (vHIT). The crHIT utilizes whole-body rotation via the chair to yield a persistent controlled, repeatable, comfortable, reliable stimulus can be delivered while recording eye movements with video-oculogaphy. |
| FILED | Tuesday, May 16, 2017 |
| APPL NO | 15/596886 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0041 (20130101) A61B 3/113 (20130101) A61B 5/4023 (20130101) Original (OR) Class A61B 5/4863 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/4228 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/13318 (20130101) G02F 1/133514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10542932 | McCully et al. |
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| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Kevin K. McCully (Athens, Georgia); Terence E. Ryan (Athens, Georgia) |
| ABSTRACT | In one embodiment, measuring mitochondrial capacity includes performing arterial occlusions on a patient, measuring oxygenated hemoglobin/myoglobin and deoxygenated hemoglobin/myoglobin within the patient's body during the occlusions, calculating a blood volume correction factor that accounts for a change in blood volume that occurs during the arterial occlusions, and applying the correction factor to the measured oxygenated hemoglobin/myoglobin and deoxygenated hemoglobin/myoglobin measurements to obtain correct oxygenated hemoglobin/myoglobin and deoxygenated hemoglobin/myoglobin measurements. |
| FILED | Wednesday, June 07, 2017 |
| APPL NO | 15/616318 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/702 (20130101) A61B 5/02028 (20130101) A61B 5/4519 (20130101) A61B 5/4866 (20130101) Original (OR) Class A61B 5/4884 (20130101) A61B 5/6828 (20130101) A61B 5/7225 (20130101) A61B 5/7278 (20130101) A61B 5/14546 (20130101) A61B 5/14551 (20130101) A61B 17/1355 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543185 | Noth et al. |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); Cornell University (Ithaca, New York) |
| INVENTOR(S) | Imre Noth (Chicago, Illinois); Justin Oldham (Chicago, Illinois); Fernando Martinez (Ithaca, New York) |
| ABSTRACT | Aspects of the disclosure relate to a method for treating idiopathic pulmonary fibrosis (IPF) in a patient with N-acetylcysteine (NAC) comprising administering NAC to a patient after a sample from the patient has been genotyped and determined to be any one of: a) homozygous or heterozygous for a thymine at the single nucleotide polymorphism rs3750920; b) homozygous or heterozygous for guanine at the single nucleotide polymorphism rs5743894; or c) homozygous or heterozygous for thymine at the single nucleotide polymorphism rs35705950. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/567988 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/198 (20130101) Original (OR) Class A61K 31/573 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543210 | Wise et al. |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas) |
| INVENTOR(S) | John G. Wise (Dallas, Texas); Pia D. Vogel (Dallas, Texas); Alexander R. Lippert (Dallas, Texas); Amila K. Nanyakkara (Dallas, Texas); Maha A. Aljowni (Dallas, Texas) |
| ABSTRACT | The present disclosure provides a method of treating a subject that is resistant to one or more drugs by identifying a subject having one or more drug resistant cells; administering to the subject a pharmaceutically effective amount of an inhibitor compound, and contacting one or more drug resistant cells with the inhibitor compound to reduce the export of the inhibitor compound from the one or more drug resistant tumor cells and to block the transport of drug(s) from the one or more drug resistant cells. |
| FILED | Wednesday, March 27, 2019 |
| APPL NO | 16/366674 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) A61K 31/4196 (20130101) A61K 31/4525 (20130101) A61K 31/5025 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543221 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida); The Regents of the University of California (Oakland, Florida) |
| INVENTOR(S) | Yu Chen (Tampa, Florida); Orville Antonio Pemberton (Tampa, Florida); Adam Renslo (Oakland, California); Priyadarshini Jaishankar (Newark, California) |
| ABSTRACT | Provided herein are heterocyclic compounds and pharmaceutical formulations that can be used to treat bacterial infections. Also provided herein are methods of making and using the heterocyclic compounds and pharmaceutical formulations. |
| FILED | Tuesday, July 31, 2018 |
| APPL NO | 16/050601 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/407 (20130101) A61K 31/407 (20130101) A61K 31/665 (20130101) A61K 31/665 (20130101) A61K 31/675 (20130101) Original (OR) Class A61K 31/675 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/60 (20130101) C07F 9/6561 (20130101) C07F 9/65522 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543231 | Bhattacharya et al. |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Santanu Bhattacharya (Ponte Vedra, Florida); Debabrata Mukhopadhyay (Rochester, Minnesota); Krishnendu Pal (Jacksonville, Florida) |
| ABSTRACT | This document provides methods and materials involved in treating cancer. For example, methods and materials involved in making and using particles (e.g., gold nanoparticles) containing a KTLLPTPYC amino acid sequence (SEQ ID NO:1) or a KTLLPTPYCC amino acid sequence (SEQ ID NO:2) to treat cancer (e.g., pancreatic cancer) are provided. |
| FILED | Wednesday, May 16, 2018 |
| APPL NO | 15/981656 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7068 (20130101) A61K 33/24 (20130101) Original (OR) Class A61K 47/52 (20170801) A61K 47/64 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543233 | Spencer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia); The UAB Research Foundation (Birmingham, Alabama); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); The UAB Research Foundation (Birmingham, Alabama); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Harold Trent Spencer (Marietta, Georgia); Anindya Dasgupta (Anderson, South Carolina); Lawrence S. Lamb (Birmingham, Alabama) |
| ABSTRACT | The present disclosure is generally related to methods for combining chemotherapy and immunotherapy for the treatment of a cancer. The methods also relate to generating a drug-resistant cytotoxic immune cell line and uses thereof in conjunction with cytotoxic drugs. |
| FILED | Friday, February 22, 2019 |
| APPL NO | 16/283669 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/4188 (20130101) A61K 31/4188 (20130101) A61K 35/12 (20130101) A61K 35/17 (20130101) Original (OR) Class A61K 35/17 (20130101) A61K 2035/124 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543252 | Desmond et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Patrick F. Desmond (Baltimore, Maryland); Robert J. Bloch (Baltimore, Maryland); Mark A. Rizzo (Nottingham, Maryland); Joaquin Muriel (New Freedom, Pennsylvania); Michele L. Markwardt (Baltimore, Maryland) |
| ABSTRACT | Embodiments of the disclosure concern methods and compositions related to the small Ankyrin 1 (sAnk1) protein and its role as a regulatory protein in at least muscle cells. In particular embodiments, its expression and/or activity are modulated with one or more compositions. In specific embodiments, compositions such as nucleic acids that inhibit expression of sAnk1 are utilized for a variety of methods, whereas in other embodiments compositions such as polypeptides, peptides, or sAnk1-encoding nucleic acids that enhance sAnk1 levels are utilized for certain methods. |
| FILED | Thursday, February 04, 2016 |
| APPL NO | 15/016086 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 38/1709 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543257 | Uchida et al. |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Naoya Uchida (Rockville, Maryland); John F. Tisdale (Washington, District of Columbia) |
| ABSTRACT | The invention is directed to a more efficient lentiviral vector comprising a nucleic acid sequence encoding a human β-globin protein or a human γ-globin protein, which is oriented from 5′ to 3′ relative to the lentiviral genome. The invention also provides a composition and method utilizing the lentiviral vector. |
| FILED | Friday, August 14, 2015 |
| APPL NO | 15/510014 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/42 (20130101) Original (OR) Class A61K 48/005 (20130101) Peptides C07K 14/805 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543258 | Park et al. |
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| APPLICANT(S) | KONKUK UNIVERSITY GLOCAL INDUSTRY-ACADEMIC COLLABORATION FOUNDATION (Chungju-si, Chungcheongbuk-do, South Korea) |
| ASSIGNEE(S) | KONKUK UNIVERSITY GLOCAL INDUSTRY-ACADEMIC COLLABORATION FOUNDATION (Chungju-si, Chungcheon, South Korea) |
| INVENTOR(S) | Yeong Min Park (Seoul, South Korea); In Duk Jung (Cheongju-si, South Korea); Yong Taik Lim (Seongnam-si, South Korea); Jung Hee Park (Iksan-si, South Korea); Sung Jae Shin (Seoul, South Korea) |
| ABSTRACT | The present invention relates to an antibacterial composition containing, as an active ingredient, adenylate kinase or adenosine kinase (ADK) protein derived from Mycobacterium tuberculosis, and a composition for preventing or treating infectious diseases. In addition, the present invention relates to a composition for preventing or treating sepsis or septic shock. Furthermore, the present invention relates to a method for preventing, improving or treating an infectious disease comprising administering the present antibacterial composition. The ADK protein derived from Mycobacterium tuberculosis according to the present invention has excellent antibacterial activity selectively against gram-negative bacteria, and thus can be favorably used as an antibacterial composition against gram-negative bacteria or for the prevention or treatment of infectious diseases caused by gram-negative bacteria. In addition, the ADK protein has an excellent sepsis treatment effects, thus can be favorably used for the prevention or treatment of sepsis or septic shock. |
| FILED | Thursday, December 10, 2015 |
| APPL NO | 15/534979 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/47 (20130101) A61K 31/65 (20130101) A61K 31/345 (20130101) A61K 31/545 (20130101) A61K 31/7036 (20130101) A61K 38/45 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1229 (20130101) Enzymes C12Y 207/04003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543259 | Dauber et al. |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | Andrew Nahum Dauber (Amberley, Ohio); Vivian Hwa (Cincinnati, Ohio) |
| ABSTRACT | The instant disclosure relates to methods useful for the treatment or prevention of progressive growth failure in a subject in need thereof. The method may include the step of administering a PAPPA2 gene product to the subject. Also disclosed is the identification of a novel gene mutation that may be used as a marker to identify subjects particularly suited for such treatment. Compositions containing a therapeutically effective amount of PAPPA2 protein and a pharmaceutically acceptable carrier are also disclosed. |
| FILED | Thursday, February 04, 2016 |
| APPL NO | 15/015410 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/4886 (20130101) Original (OR) Class A61K 48/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 304/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543263 | Orentas et al. |
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| APPLICANT(S) | LentigenTechnology, Inc. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Lentigen Technology Inc. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Rimas J. Orentas (Seattle, Washington); Dina Schneider (Potomac, Maryland); Boro Dropulic (Ellicott City, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland) |
| ABSTRACT | Chimeric antigen receptors (CARs) containing CD22 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the CARs are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making CAR T cells are also disclosed. |
| FILED | Tuesday, October 16, 2018 |
| APPL NO | 16/161542 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/001113 (20180801) Original (OR) Class A61K 2039/5156 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 16/2803 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543264 | Vujanovic et al. |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Nikola L. Vujanovic (Pittsburgh, Pennsylvania); Lazar Vujanovic (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods are disclosed for inhibiting the development of a tumor in a subject. The methods include administering to a subject a therapeutically effective amount of a dominant negative tumor necrosis factor (DN-TNF)-α protein and/or a nucleic acid encoding the DN-TNF-α protein. The DN-TNF-α protein and/or a nucleic acid encoding the DN-TNF-α protein can be administered alone or in combination with other agents. |
| FILED | Wednesday, December 14, 2016 |
| APPL NO | 15/776061 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/2013 (20130101) A61K 38/2046 (20130101) A61K 38/2086 (20130101) A61K 39/00114 (20180801) A61K 39/001117 (20180801) Original (OR) Class A61K 39/001139 (20180801) A61K 45/06 (20130101) A61K 2039/57 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543268 | Palese et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York); St. Jude Children's Research Hospital (Memphis, Tennessee); The United States of America, As Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); St. Jude Children's Research Hospital (Memphis, Tennessee); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Peter Palese (New York, New York); Adolfo Garcia-Sastre (New York, New York); Richard J. Webby (Memphis, Tennessee); Juergen A. Richt (Ames, Iowa); Robert G. Webster (Memphis, Tennessee); Kelly M. Lager (Colo, Iowa) |
| ABSTRACT | The present invention relates, in general, to attenuated swine influenza viruses having an impaired ability to antagonize the cellular interferon (IFN) response, and the use of such attenuated viruses in vaccine and pharmaceutical formulations. In particular, the invention relates to attenuated swine influenza viruses having modifications to a swine NS1 gene that diminish or eliminate the ability of the NS1 gene product to antagonize the cellular IFN response. These viruses replicate in vivo, but demonstrate decreased replication, virulence and increased attenuation, and therefore are well suited for use in live virus vaccines, and pharmaceutical formulations. |
| FILED | Monday, September 10, 2018 |
| APPL NO | 16/126791 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/58 (20130101) A61K 2039/544 (20130101) A61K 2039/552 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16034 (20130101) C12N 2760/16061 (20130101) C12N 2760/16121 (20130101) C12N 2760/16134 (20130101) C12N 2760/16151 (20130101) C12N 2760/16171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543282 | Naleway et al. |
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| FUNDED BY |
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| APPLICANT(S) | Marker Gene Technologies, Inc. (Eugene, Oregon) |
| ASSIGNEE(S) | Marker Gene Technologies, Inc (Eugene, Oregon) |
| INVENTOR(S) | John Joseph Naleway (Eugene, Oregon); Fiona Karen Harlan (Eugene, Oregon); Jason Scott Lusk (Eugene, Oregon) |
| ABSTRACT | The present invention relates to the preparation and use of therapeutic compounds for the treatment of diseases at specific subcellular target areas such as specific cellular organelles. In particular, the therapeutic compounds of the invention are specific for modifying enzyme activity within targeted organelles or structures of cells and tissues. Subcellular organelles and structures that may be specifically targeted by compounds of the present invention include lysosomes, autophagasomes, the endoplasmic reticulum, the Golgi complex, peroxisomes, the nucleus, membranes and the mitochondria. |
| FILED | Wednesday, March 21, 2018 |
| APPL NO | 15/927579 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/445 (20130101) A61K 47/64 (20170801) Original (OR) Class A61K 47/645 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543283 | Esko et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Jeffrey D. Esko (San Diego, California); Yitzhak Tor (San Diego, California); Wenyong Tong (San Diego, California) |
| ABSTRACT | This disclosure relates to intranasal administration of conjugates comprising guanidinylated aminoglycosides (“guanidinoglycosides”) and a polypeptide (e.g., an enzyme, antibody, or polypeptide growth factor). For example, such administration methods are useful for delivering a polypeptide to the brain and/or cerebrospinal fluid. Such methods are useful for treating a lysosomal storage disease through intranasal administration of a conjugate comprising one or more guanidinoglycosides and an enzyme useful for treating a lysosomal storage disease. |
| FILED | Wednesday, September 06, 2017 |
| APPL NO | 15/696690 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 38/46 (20130101) A61K 38/47 (20130101) A61K 39/39533 (20130101) A61K 47/62 (20170801) A61K 47/67 (20170801) Original (OR) Class A61K 47/552 (20170801) Enzymes C12Y 302/01076 (20130101) C12Y 310/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543285 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Researh Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Jian Yang (State College, Pennsylvania); Cheng Dong (State College, Pennsylvania); Zhiwei Xie (State College, Pennsylvania) |
| ABSTRACT | In one aspect, methods of targeted nanoparticle and cell delivery are described herein. In some embodiments, methods described herein comprise coupling nanoparticles and cells to a carrier cell to form a nanoparticle-cell conjugate or cell-cell conjugate, disposing the nanoparticle-cell or cell-cell conjugate in a biological environment, and delivering the nanoparticles and cells to target cells or tissues located within the biological environment. The nanoparticles comprise a biodegradable photoluminescent polymer, and the nanoparticle-cell conjugate is formed using one or more click chemistry reaction products. |
| FILED | Thursday, April 13, 2017 |
| APPL NO | 16/089824 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 47/65 (20170801) A61K 47/593 (20170801) A61K 47/6901 (20170801) Original (OR) Class A61K 47/6937 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543286 | Bahou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Wadie F. Bahou (Setauket, New York); Song Wu (Stony Brook, New York) |
| ABSTRACT | The present disclosure provides methods of treating a human having a disease or disorder that would benefit from increasing platelet counts. The method involves inhibiting the enzyme activity of biliverdin IXβ reductase (BLVRB) activity or inhibiting the expression of BLVRB gene. |
| FILED | Wednesday, October 05, 2016 |
| APPL NO | 15/765317 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/19 (20130101) A61K 48/0016 (20130101) A61K 48/0066 (20130101) Original (OR) Class A61K 48/0083 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/02 (20180101) Enzymes C12Y 103/01024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543287 | Langenau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | David M. Langenau (Stoneham, Massachusetts); Jessica Susanne Blackburn (Chelmsford, Massachusetts) |
| ABSTRACT | Genetically-modified zebrafish lacking one or more immune-related genes, and the use thereof, e.g., in cell or tissue transplantation methods or in stem cell biology. In a first aspect, the invention provides a genetically-modified fish whose genome is homozygous for engineered or induced genetic alteration, e.g., an alteration that changes the sequence of the genomic ONA resulting in insertion and deletion of nucleotides that disrupt protein function or shift the frame of translation leading to premature protein termination, in one or more immune-related genes selected from the group consisting of: foxn1, rag2, jak3, prkdc, and interleukin 2-receptor gamma a and (IL2RGa and IL2RGb), wherein the genetic alteration results in an inactivation (i.e., loss of expression or function) of both alleles of the immune-related gene. |
| FILED | Wednesday, July 09, 2014 |
| APPL NO | 14/903940 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 2207/12 (20130101) A01K 2227/40 (20130101) A01K 2267/0331 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543313 | Damiano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Edward R. Damiano (Acton, Massachusetts); Firas H. El-Khatib (Allston, Massachusetts) |
| ABSTRACT | Apparatus and methods calculate and deliver doses of insulin and optionally glucagon into a subject. Online operation controls delivery of correction doses of insulin automatically in response to regular glucose measurements from a sensor, and offline operation calculates and delivers correction doses based on isolated glucose measurements and information gathered autonomously during preceding online operation. In another aspect, offline operation includes automatically calculating and administering meal doses based on information gathered autonomously during preceding periods of online operation. Both methods include generating relevant control parameters tailored to the individual and continually converged upon and potentially modulated during online operation. The control parameters are employed in real time during periods of offline operation to regulate glucose level without the need for user-provided control parameters such as correction factors and insulin-to-carbohydrate ratios. |
| FILED | Thursday, July 28, 2016 |
| APPL NO | 15/221871 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 5/16827 (20130101) A61M 2202/07 (20130101) A61M 2205/50 (20130101) A61M 2205/502 (20130101) A61M 2205/3584 (20130101) A61M 2230/005 (20130101) A61M 2230/201 (20130101) Electric Digital Data Processing G06F 19/3468 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543328 | Kayyali et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hani Kayyali (Shaker Heights, Ohio); Daniel Bishop (Tallmadge, Ohio); Brian M. Kolkowski (Leroy, Ohio) |
| ASSIGNEE(S) | Cleveland Medical Devices Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Hani Kayyali (Shaker Heights, Ohio); Daniel Bishop (Tallmadge, Ohio); Brian M. Kolkowski (Leroy, Ohio) |
| ABSTRACT | The present invention relates to an integrated sleep diagnosis and treatment device, and more particularly to an integrated apnea diagnosis and treatment device. The present invention additionally relates to methods of sleep diagnosis and treatment. The sleep disorder treatment system of the present invention can use a diagnosis device to perform various forms of analysis to determine or diagnose a subject's sleeping disorder or symptoms of a subject's sleep disorder, and using this analysis or diagnosis can with or in some embodiments without human intervention treat the subject either physically or chemically to improve the sleeping disorder or the symptoms of the sleeping disorder. The diagnostic part of the system can use many different types of sensors and methods for diagnosing the severity of the symptoms of or the sleep disorder itself. The treatment part of the system can use a device to physically or chemically treat the subject's symptoms or sleep disorder itself. |
| FILED | Friday, November 18, 2016 |
| APPL NO | 15/355189 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0013 (20130101) A61B 5/0077 (20130101) A61B 5/1135 (20130101) A61B 5/4818 (20130101) A61B 5/14552 (20130101) A61B 2560/0443 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/12 (20130101) A61M 16/0069 (20140204) Original (OR) Class A61M 2202/0225 (20130101) A61M 2205/3303 (20130101) A61M 2205/3592 (20130101) A61M 2205/8206 (20130101) A61M 2230/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543337 | Meyerhoff et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Mark E. Meyerhoff (Ann Arbor, Michigan); Lajos Hofler (Oxford, United Kingdom); Dipankar Koley (Ann Arbor, Michigan); Hang Ren (Ann Arbor, Michigan) |
| ABSTRACT | A gas delivery device includes a nitric oxide generating system. The system has a medium including i) a source of nitrite ions, or ii) a source of nitrite ions and a Cu(II)-ligand complex. A working electrode is in contact with the medium, wherein i) when the medium includes the source of nitrite ions, the working electrode is a copper containing conductive material or a base material coated with a copper containing conductive material, or ii) when the medium includes the source of nitrite ions and the Cu(II)-ligand complex, the working electrode is platinum, gold, carbon, a carbon coated material, and/or mercury. A reference/counter electrode is in contact with the medium and electrically isolated from the working electrode. An inlet conduit is to deliver oxygen gas to the medium, and an outlet conduit is to transport a stream of oxygen gas and nitric oxide from the medium. |
| FILED | Tuesday, August 02, 2016 |
| APPL NO | 15/226769 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/342 (20130101) A61M 1/1698 (20130101) A61M 16/12 (20130101) Original (OR) Class A61M 25/0043 (20130101) A61M 35/00 (20130101) A61M 2025/0057 (20130101) A61M 2202/0208 (20130101) A61M 2202/0275 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543339 | Hofius et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI INTERNATIONAL (Menlo Park, California); Chunyuan Qiu (Menlo Park, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | Jonathan Hofius (Menlo Park, California); Chunyuan Qiu (Menlo Park, California); Manish Kothari (Menlo Park, California) |
| ABSTRACT | Devices, systems and methods are used to decouple proximal movement of a catheter supply lead or tubing from the tissue-embedded catheter. A catheter decoupling device comprises a catheter hub, sled and track, wherein the hub comprises a proximal end configured to receive a catheter fluid supply device, and a distal end configured to receive a catheter, the sled receives and retains the hub, the track receives and retains the hub; and, the hub has a limited range of back-and-forth motion relative to the track. |
| FILED | Tuesday, August 22, 2017 |
| APPL NO | 15/683291 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/16813 (20130101) A61M 25/0097 (20130101) Original (OR) Class A61M 39/20 (20130101) A61M 39/1011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543382 | Rockweiler et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Holly Elizabeth Rockweiler (Portland, Oregon); Ryan Taylor Krone (Portland, Oregon); Jonathan Daniel Steinberger (Portland, Oregon); Kathryn Olson (Redwood City, California) |
| ABSTRACT | A method of treating vaginal tissue atrophy in a female subject, the method including the steps of engaging an energy delivery element with tissue in or around the subject's vagina; applying energy to the tissue from the energy delivery element; and increasing blood flow to internal vaginal tissue to an increased level above a baseline level of blood flow to the internal vaginal tissue, the increased level of blood flow to the internal vaginal tissue persisting after the applying step ceases. The invention also provides devices for performing this therapy. |
| FILED | Monday, January 26, 2015 |
| APPL NO | 15/111099 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/026 (20130101) A61B 5/4294 (20130101) A61B 5/4337 (20130101) A61B 5/4836 (20130101) A61B 2017/2253 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543485 | Ismagilov et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Rustem F. Ismagilov (Chicago, Illinois); Wenbin Du (Chicago, Illinois); Liang Li (Chicago, Illinois); Feng Shen (Chicago, Illinois); Kevin Paul Flood Nichols (Chicago, Illinois); Delai Chen (Cambridge, Massachusetts); Jason Eugene Kreutz (Chicago, Illinois) |
| ABSTRACT | A device is described having a first surface having a plurality of first areas and a second surface having a plurality of second areas. The first surface and the second surface are opposed to one another and can move relative to each other from at least a first position where none of the plurality of first areas, having a first substance, are exposed to plurality of second areas, having a second substance, to a second position. When in the second position, the plurality of first and second areas, and therefore the first and second substances, are exposed to one another. The device may further include a series of ducts in communication with a plurality of first second areas to allow for a substance to be disposed in, or upon, the plurality of second areas when in the first position. |
| FILED | Wednesday, May 25, 2016 |
| APPL NO | 15/164788 |
| ART UNIT | 1799 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/0094 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5025 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 3/502738 (20130101) B01L 3/502761 (20130101) B01L 7/52 (20130101) B01L 2200/025 (20130101) B01L 2200/027 (20130101) B01L 2300/12 (20130101) B01L 2300/168 (20130101) B01L 2300/0609 (20130101) B01L 2300/0809 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0887 (20130101) B01L 2300/0893 (20130101) B01L 2400/065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) C12Q 1/703 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 33/54386 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544075 | Scanlan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| INVENTOR(S) | Thomas Scanlan (Portland, Oregon); Jordan Devereaux (Portland, Oregon); Andrew Placzek (Portland, Oregon); Tapasree Banerji (Portland, Oregon); Skylar Ferrara (Portland, Oregon); James Matthew Meinig (Portland, Oregon); Tania Banerji (Portland, Oregon) |
| ABSTRACT | Disclosed are halo substituted derivative compounds of sobetirome with improved pharmacological characteristics relative to sobetirome, pharmaceutical compositions that include those compounds and methods of treating diseases such as neurodegenerative disorders using those pharmaceutical compositions. |
| FILED | Thursday, May 18, 2017 |
| APPL NO | 16/301711 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 39/07 (20130101) C07C 43/315 (20130101) Original (OR) Class C07C 59/115 (20130101) C07C 65/34 (20130101) C07C 235/20 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544104 | Van Voorhis et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO (Seattle, Washington) |
| INVENTOR(S) | Wesley C. Van Voorhis (Seattle, Washington); Wilhelmus G. J. Hol (Kenmore, Washington); Eric T. Larson (Shoreline, Washington); Dustin James Maly (Seattle, Washington); Ethan Merritt (Seattle, Washington); Kayode K. Ojo (Federal Way, Washington) |
| ABSTRACT | Compositions and methods for the treatment of toxoplasmosis, caused by the infectious eukaryotic parasite Toxoplasma gondii (T. gondii) and for the treatment of cryptosporidiosis, caused by the infectious eukaryotic parasites Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) are described. In particular, the present disclosure is directed to compositions and methods for inhibiting either T. gondii calcium dependent protein kinases (TgCDPKs) or C. parvum and C. hominus calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the formula, wherein the variables X, Y, Z, L, R1, and R3 are defined herein. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/686839 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 235/30 (20130101) Original (OR) Class C07D 235/32 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544110 | Wipf et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Peter Wipf (Pittsburgh, Pennsylvania); James K. Johnson (Pittsburgh, Pennsylvania); Erin M. Skoda (Columbia, Maryland); Joel B. Nelson (Pittsburgh, Pennsylvania); Zhou Wang (Pittsburg, Pennsylvania) |
| ABSTRACT | A compound, or a pharmaceutically acceptable salt or ester thereof, according to formula I: R20—(Z)b—(Y)c—(R21)a—(X)d—R22—R23 wherein R20 is aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a thio-containing group, or a seleno-containing group; Z is alkanediyl, substituted alkanediyl, cycloalkanediyl, or substituted cycloalkanediyl; Y is S, O, S(═O), —S(═O)(═O)—, or NR10, wherein R10 is H or alkyl; R21 is alkanediyl, substituted alkanediyl, cycloalkanediyl, substituted cycloalkanediyl alkadienyl, substituted alkadienyl, alkatrienyl, substituted alkatrienyl; X is —C(═O)—, —S(═O)(═O)—, or —N(H)C(═O)—; R22 includes at least one divalent amino radical; R23 is aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a thio-containing group, or a seleno-containing group; a, b, c, and d independently are 0 or 1. |
| FILED | Tuesday, April 24, 2018 |
| APPL NO | 15/961475 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/46 (20130101) A61K 31/58 (20130101) A61K 31/454 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) A61K 31/4166 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 261/08 (20130101) Original (OR) Class C07D 295/185 (20130101) C07D 413/12 (20130101) C07D 451/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544117 | Canney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Temple University Of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Daniel J. Canney (Ambler, Pennsylvania); Benjamin E. Blass (Philadelphia, Pennsylvania); Rong Gao (Eugene, Oregon); Magid Abou-Gharbia (Exton, Pennsylvania) |
| ABSTRACT | Pharmaceutical compositions of the invention comprise functionalized lactone derivatives of formula (I) having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity. |
| FILED | Thursday, September 10, 2015 |
| APPL NO | 15/510152 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 307/33 (20130101) Original (OR) Class C07D 307/94 (20130101) C07D 405/06 (20130101) C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544136 | Roberts et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Edward Roberts (Fallbrook, California); Hugh Rosen (La Jolla, California); Steven Brown (San Diego, California); Miguel A. Guerrero (San Diego, California); Xuemei Peng (La Jolla, California); Ramulu Poddutoori (La Jolla, California) |
| ABSTRACT | Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided. |
| FILED | Monday, April 23, 2018 |
| APPL NO | 15/959935 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4245 (20130101) Heterocyclic Compounds C07D 263/32 (20130101) C07D 271/06 (20130101) C07D 401/04 (20130101) C07D 413/04 (20130101) Original (OR) Class C07D 413/14 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544138 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Hai-Tsang Huang (Boston, Massachusetts); Yubao Wang (Newton, Massachusetts); Jean Zhao (Brookline, Massachusetts); Hwan Geun Choi (Seoul, South Korea) |
| ABSTRACT | Provided herein are tricyclic small molecule inhibitors of maternal embryonic leucine zipper kinase (MELK). The compounds are useful for treating cancer and other conditions or diseases associated with aberrant MELK expression. Also provided herein are pharmaceutical compositions comprising a tricyclic compound of the invention and a pharmaceutically acceptable carrier. The invention also provides methods of treating cancers associated with over-expression of MELK. |
| FILED | Friday, March 04, 2016 |
| APPL NO | 15/554595 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/519 (20130101) A61K 31/4745 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544152 | Cunningham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kathryn A. Cunningham (Galveston, Texas); Scott R. Gilbertson (Houston, Texas) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas); University of Houston System (Houston, Texas) |
| INVENTOR(S) | Kathryn A. Cunningham (Galveston, Texas); Scott R. Gilbertson (Houston, Texas) |
| ABSTRACT | The invention relates to the novel analogs of selective 5HT2CR agonist WAY163909, the preparation, and the use thereof. |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/048216 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544159 | Fasan et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Rudi Fasan (Rochester, New York); Kai-Dong Zhang (Langley, Canada) |
| ABSTRACT | Derivatives of the antimalarial agent artemisinin, compositions comprising the derivatives, methods for preparing the derivatives, and their uses in pharmaceutical compositions intended for the treatment of parasitic infections are provided. Methods are provided for the production of artemisinin derivatives via functionalization of positions C7 and C6a, and optionally, in conjunction with modifications at positions C10 and C9, via chemoenzymatic methods. Recombinant cytochrome P450 polypeptides are also provided for use in the methods. The artemisinin derivatives can be used for the treatment of malaria and other parasitic infections, alone or in combination with other antiparasitic drugs. |
| FILED | Thursday, April 20, 2017 |
| APPL NO | 15/492180 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 491/18 (20130101) C07D 493/18 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0042 (20130101) C12N 9/0071 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/181 (20130101) Enzymes C12Y 106/02004 (20130101) C12Y 114/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544176 | Slusher et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR v.v.i. (Prague, Czech Republic) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Barbara Slusher (Kingsville, Maryland); Rana Rais (Kingsville, Maryland); Marcela Krecmerova (Prague, Czech Republic); Tomas Tichy (Prague, Czech Republic); Pavel Majer (Sykesville, Maryland); Andrej Jancarik (Koprivnice, Czech Republic) |
| ABSTRACT | Methods and compounds are disclosed for treating a disease or condition by inhibiting PSMA (Prostate Specific Membrane Antigen) using prodrugs of 2-PMPA. |
| FILED | Tuesday, May 01, 2018 |
| APPL NO | 15/968074 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/3808 (20130101) C07F 9/4006 (20130101) C07F 9/4075 (20130101) C07F 9/4084 (20130101) C07F 9/4087 (20130101) C07F 9/4465 (20130101) C07F 9/65586 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544182 | Myers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Presidents and Fellow of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Andrew G. Myers (Boston, Massachusetts); Ziyang Zhang (San Francisco, California) |
| ABSTRACT | The present invention provides desosamine and mycaminose analogs and nitro sugars and methods for their preparation. The invention also provides methods of cyclizing a compound of Formula (A′) with glyoxal to give a nitro sugar of Formula (B). Methods for the preparation of compound of Formula (D′) are provided comprising cyclization of a nitro alcohol to give a nitro sugar and reduction and alkylation of the nitro sugar to give a desosamine, mycaminose, or an analog thereof. |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/558910 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 201/12 (20130101) C07C 201/14 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 11/02 (20130101) C07H 15/12 (20130101) Original (OR) Class C07H 15/18 (20130101) C07H 17/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544188 | Cosford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Nicholas David Peter Cosford (La Jolla, California); Mitchell Dennis Vamos (La Jolla, California) |
| ABSTRACT | Provided herein are compounds that modulate the activity of inhibitor of apoptosis proteins (IAPs), compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/031837 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Heterocyclic Compounds C07D 487/04 (20130101) C07D 487/14 (20130101) C07D 498/04 (20130101) C07D 498/10 (20130101) C07D 513/04 (20130101) Peptides C07K 5/0806 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544191 | Fasan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Rudi Fasan (Rochester, New York) |
| ABSTRACT | Methods and compositions are provided for generating macrocyclic peptides from genetically encoded, ribosomally produced polypeptide precursors. Also provided are nucleic acid molecules, polypeptides, and methods for generating combinatorial libraries of macrocyclic peptides. These methods can be used to produce vast libraries of conformationally constrained peptide ligands as well as facilitate the functional screening of these libraries to identify compound(s) with desired activity properties. |
| FILED | Tuesday, December 23, 2014 |
| APPL NO | 15/107387 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 7/54 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544207 | Palese et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Peter Palese (New York, New York); Adolfo Garcia-Sastre (New York, New York); Gene Tan (New York, New York) |
| ABSTRACT | Provided herein are antibodies that cross-react with hemagglutinin from strains of influenza virus of the same subtype or different subtypes, host cells for producing such antibodies, and kits comprising such antibodies. Also provided herein are compositions comprising antibodies that cross-react with hemagglutinin from strains of influenza virus of the same subtype or different subtypes and methods of using such antibodies to diagnose, prevent or treat influenza virus disease. |
| FILED | Monday, January 22, 2018 |
| APPL NO | 15/877285 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6841 (20170801) A61K 2039/505 (20130101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/33 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/11 (20130101) G01N 2469/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544392 | Gros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Alena Gros (Washington, District of Columbia); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed are methods of isolating T cells and TCRs having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation. Also disclosed are related methods of preparing a population of cells, populations of cells, TCRs, pharmaceutical compositions, and methods of treating or preventing cancer. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/567157 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1703 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544393 | Murphy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Boston Medical Center Corporation (Boston, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Boston Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | George J. Murphy (Boston, Massachusetts); David H. Sherr (West Roxbury, Massachusetts); Sarah S. Rozelle (Jamaica Plain, Massachusetts); Brenden W. Smith (Warwick, Rhode Island) |
| ABSTRACT | This disclosure provides methods of making a megakaryocyte-erythroid progenitor cell (MEP), comprising differentiating a stem cell into a MEP in culture in the presence of an aryl hydrocarbon receptor (AhR) agonist. In some embodiments the stem cell is a pluripotent stem cell. In some embodiments the MEP co-expresses CD41 and CD235. In some embodiments the number of MEPs produced in the culture increases exponentially. Methods of making a red blood cell (RBC) by culturing a MEP in the presence of an AhR agonist are also provided. Methods of making a megakaryocyte and/or a platelet, comprising culturing a MEP in the presence of an AhR modulator are also provided. In some embodiments the AhR modulator is an AhR antagonist. This disclosure also provides compositions comprising at least 1 million MEPs per ml and compositions in which at least 50% of the cells are MEPs. |
| FILED | Tuesday, June 02, 2015 |
| APPL NO | 14/729008 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/655 (20130101) A61K 35/18 (20130101) A61K 35/19 (20130101) A61K 45/06 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0641 (20130101) C12N 5/0644 (20130101) C12N 5/0647 (20130101) Original (OR) Class C12N 2501/60 (20130101) C12N 2501/998 (20130101) C12N 2501/999 (20130101) C12N 2506/03 (20130101) C12N 2506/45 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/80 (20130101) G01N 33/86 (20130101) G01N 33/5044 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544399 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novavax, Inc. (Gaithersburg, Maryland) |
| ASSIGNEE(S) | Novavax, Inc. (Gaithersburg, Maryland) |
| INVENTOR(S) | Gale Smith (Germantown, Maryland); Yingyun Wu (Clarksburg, Maryland); Michael J. Massare (Mt. Airy, Maryland); Peter M. Pushko (Frederick, Maryland); Margaret Nathan (Montgomery Village, Maryland); Thomas Kort (Germantown, Maryland); Robin Robinson (Dickerson, Maryland) |
| ABSTRACT | This invention discloses a method of increasing production of virus-like particles comprising expressing an avian influenza matrix protein. The invention also comprises methods of making and using said VLPs. |
| FILED | Thursday, March 22, 2018 |
| APPL NO | 15/928385 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/5258 (20130101) A61K 2039/55505 (20130101) A61K 2039/55555 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/01 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/2402 (20130101) C12N 2710/14143 (20130101) C12N 2760/16122 (20130101) C12N 2760/16123 (20130101) C12N 2760/16134 (20130101) C12N 2760/16151 (20130101) C12N 2760/16171 (20130101) C12N 2760/16222 (20130101) C12N 2760/16223 (20130101) C12N 2760/16251 (20130101) C12N 2770/20022 (20130101) C12N 2770/20023 (20130101) C12N 2770/20051 (20130101) C12N 2800/22 (20130101) Enzymes C12Y 302/01018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544405 | Weiss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | David S. Weiss (Decatur, Georgia); Arash Grakoui (Decatur, Georgia); Timothy R. Sampson (Los Angeles, California); Aryn Alaine Price (Tipton, Missouri) |
| ABSTRACT | This disclosure relates to Cas9-nucleic acid complexes and uses related thereto. In certain embodiments, the disclosure contemplates transgenic plants and animals genetically engineered to express Cas9-nucleic acid complexes disclosed herein. In certain embodiments, the disclosure relates to methods of treating or preventing, diseases, conditions, cancer, viral infections or other pathogenic infection using vectors configured to express a Cas9-nucleic acid complex disclosed herein. |
| FILED | Wednesday, January 15, 2014 |
| APPL NO | 14/760113 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544407 | Fischetti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Vincent A. Fischetti (New York, New York); Jonathan Schmitz (New York, New York); Daniel Gilmer (New York, New York); Chad Euler (New York, New York) |
| ABSTRACT | The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, including Streptococcus and Staphylococcus, and related conditions. The invention provides compositions and methods incorporating and utilizing Streptococcus suis derived bacteriophage lysins, particularly PlySs2 and/or PlySs1 lytic enzymes and variants thereof, including truncations thereof. Methods for treatment of humans are provided. |
| FILED | Thursday, April 20, 2017 |
| APPL NO | 15/492128 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/47 (20130101) A61K 38/50 (20130101) A61K 38/162 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2462 (20130101) Original (OR) Class Enzymes C12Y 302/01017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544412 | Krauss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brandeis University (Waltham, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Isaac J. Krauss (Waltham, Massachusetts); Satoru Horiya (Waltham, Massachusetts); Yollete V. Guillen Schlippe (Boston, Massachusetts) |
| ABSTRACT | The invention relates to a method for selecting a glycopolypeptide that binds to a target protein, the method including the steps of providing a pool of glycopolypeptides fused via puromycin linker to an encoding mRNA-cDNA duplex; combining the pool with a target protein to form a mixture; incubating the mixture for a period of time sufficient to allow any target protein to bind to one or more of the glycopolypeptides, thereby forming glycopolypeptide-target protein complexes; and isolating from the mixture the glycopolypeptide-target protein complexes, thereby identifying a plurality of selected glycopolypeptides. |
| FILED | Tuesday, December 02, 2014 |
| APPL NO | 15/101248 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 2039/575 (20130101) Peptides C07K 16/1063 (20130101) C07K 19/00 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2319/91 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1058 (20130101) Original (OR) Class C12N 15/1062 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544415 | Talchai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees Of Columbia University In The City Of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Chutima Talchai (New York, New York); Domenico Accili (New York, New York) |
| ABSTRACT | Methods are described for producing enteroendocrine cells that make and secrete insulin in a mammal by blocking the expression or biological activity of one or more forkhead box O (Foxo) proteins or biologically active fragments or variants thereof. |
| FILED | Friday, August 19, 2016 |
| APPL NO | 15/241674 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 39/3955 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/068 (20130101) C12N 5/0678 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 33/5073 (20130101) G01N 2333/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544433 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Shengdar Tsai (Charlestown, Massachusetts) |
| ABSTRACT | Many studies have shown that CRISPR-Cas nucleases can tolerate up to five mismatches and still cleave; it is hard to predict the effects of any given single or combination of mismatches on activity. Taken together, these nucleases can show significant off-target effects but it can be challenging to predict these sites. Described herein are methods for increasing the specificity of genome editing using the CRISPR/Cas system, e.g., using RNA-guided Foki Nucleases (RFNs), e.g., Fokl-Cas9 or Foki-dCas9-based fusion proteins. |
| FILED | Friday, June 08, 2018 |
| APPL NO | 16/003973 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 14/195 (20130101) C07K 2319/00 (20130101) C07K 2319/01 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/22 (20130101) C12N 9/0071 (20130101) C12N 9/96 (20130101) C12N 9/1007 (20130101) C12N 15/01 (20130101) C12N 15/11 (20130101) C12N 15/63 (20130101) C12N 15/85 (20130101) C12N 15/102 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 15/1031 (20130101) C12N 2310/20 (20170501) C12N 2710/00033 (20130101) C12N 2770/00033 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 114/11 (20130101) C12Y 201/01 (20130101) C12Y 301/00 (20130101) C12Y 301/21004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544443 | Kellum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | John Alston Kellum (Pittsburgh, Pennsylvania); John D. Hempel (North Braddock, Pennsylvania); Robert Hugh Edgar (Pittsburgh, Pennsylvania); John Andrew Viator (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method of detecting a species, strain or type of bacteria includes mixing a labeled bacteriophage including a label that is detectible via a detection system with a bacterial culture including the species, strain or type of bacteria to which the labeled bacteriophage selectively binds and using the detection system to detect the labeled bacteriophage bound to the species, strain or type of bacteria. |
| FILED | Friday, July 29, 2016 |
| APPL NO | 15/748490 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/02 (20130101) C12N 2795/10321 (20130101) C12N 2795/10331 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 29/2425 (20130101) G01N 2015/1006 (20130101) G01N 2291/02466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544444 | VanNieuwenhze et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Michael S. VanNieuwenhze (Bloomington, Indiana); Edward Hall (Bloomington, Indiana); Erkin Kuru (Bloomington, Indiana); Pamela Brown (Columbia, Missouri); Srinivas Tekkam (Bloomington, Indiana); Velocity Hughes (Bloomington, Indiana); Yves Brun (Bloomington, Indiana) |
| ABSTRACT | Disclosed herein are compositions for assessing peptidoglycan biosynthesis in bacteria, for identifying bacteria, and for screening for bacterial cell wall-acting and/or cell wall-disrupting agents via modified D-amino acids and methods of use thereof. Also disclosed are live bacteria having one or more modified D-amino acids as described herein incorporated into peptidoglycan of a bacterial cell wall. |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/048000 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 271/20 (20130101) Heterocyclic Compounds C07D 311/74 (20130101) Peptides C07K 9/003 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) C12Q 1/025 (20130101) C12Q 1/045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544459 | Targan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Stephan R. Targan (Santa Monica, California); Marla C. Dubinsky (Los Angeles, California); Carol J. Landers (Los Angeles, California); Ling Mei (Pasadena, California); Jerome I. Rotter (Los Angeles, California); Kent D. Taylor (Ventura, California) |
| ABSTRACT | This invention provides methods of diagnosis, predicting and diagnosing susceptibility to, predicting disease progression and treatment of inflammatory bowel disease (IBD), including Crohn's disease and/or subtypes of Crohn's disease (CD) and/or Ulcerative Colitis (UC). In one embodiment, a method of the invention is practiced by determining the presence or absence of the genetic variants NOD2, TLR8, TLR2, CARD8, CARD15 and/or JAK3 to diagnose, predict and diagnose susceptibility and predict disease progression in an individual. In another embodiment, a method of the invention is practiced by determining the presence or absence of anti-Cbir1, anti-OmpC, ASCA, anti-I2 and/or pANCA in an individual. In another embodiment, the invention further associates the presence or absence of the risk variants with the expression of anti-Cbir1, anti-OmpC, ASCA, anti-I2 and/or pANCA for the diagnosis, prediction of susceptibility, prediction of disease progression and/or treatment of IBD, including CD and/or UC. |
| FILED | Friday, May 29, 2015 |
| APPL NO | 14/726343 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/50 (20130101) G01N 2800/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544461 | Pevsner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); KENNEDY KRIEGER INSTITUTE (Baltimore, Maryland); DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Kennedy Krieger Institute, Inc. (Baltimore, Maryland); Duke University (Durham, North Carolina) |
| INVENTOR(S) | Jonathan Pevsner (Baltimore, Maryland); Anne Comi (Baltimore, Maryland); Douglas Marchuk (Chapel Hill, North Carolina); Matthew Shirley (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to the fields of neurological and skin disorders. More specifically, the present invention provides methods and compositions for diagnosing and prognosing Sturge-Weber Syndrome (SWS), Klippel-Trenaunay-Weber Syndrome (KTWS), and Port Wine Stains (PWS). In one embodiment, a method for prognosing or monitoring treatment of a patient with SWS, KTWS and/or PWS comprises the steps of (a) providing a sample from the patient undergoing treatment; (b) determining the number of alleles in the sample comprising at least one activating somatic mutation in the guanine nucleotide-binding protein G subunit alpha (GNAQ) gene or protein; (c) comparing the number of alleles comprising the at least one somatic mutation to the number of alleles comprising the somatic mutation from a patient sample provided prior to undergoing treatment; and (d) determining that the patient is improving if there is a decrease in the number of alleles comprising the at least one somatic mutation from the sample of step (a). |
| FILED | Wednesday, April 16, 2014 |
| APPL NO | 14/784720 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544464 | |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Michael Mingzhao Xing (Clarksville, Maryland) |
| ABSTRACT | The present invention relates to the field of cancer. More specifically, the present invention provides methods and compositions related to certain promoter mutations in cancer. In one embodiment, a method for treating a subject having thyroid cancer comprises the steps of (a) obtaining a biological sample from the subject; (b) performing an assay on the sample obtained from the subject to identify a mutation at 1 295 228 C>T (C228T) and 1 295 250 C>T (C250T), corresponding to −124 C>T and −146 C>T from the translation start site in the promoter of the telomerase reverse transcriptase (TERT) gene; (c) identifying the subject as having or likely to develop aggressive thyroid cancer if the C228T and/or C250T mutation is identified; and (d) treating the subject with one or more treatment modalities appropriate for a subject having or likely to develop aggressive thyroid cancer. |
| FILED | Thursday, March 27, 2014 |
| APPL NO | 14/780600 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545026 | Schaefer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Philip Raymond Schaefer (Weaverville, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip Raymond Schaefer (Weaverville, North Carolina) |
| ABSTRACT | A method provides navigation assistance to a user by tracking the user's position. By detecting similar features, the accuracy of the position measurement of the user is improved, making use of a priori frequencies that various feature types exist in the area. The method provides techniques for planning a route using the tracking information and is able to explore previously-untraveled paths in response to a setting in the search process. The navigation information can be saved or retrieved from a database so that users may share the data obtained during navigating an unfamiliar area. |
| FILED | Monday, June 04, 2018 |
| APPL NO | 15/997552 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/343 (20130101) G01C 21/3476 (20130101) Original (OR) Class G01C 21/3484 (20130101) G01C 21/3617 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545133 | Ewald et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Andrew Josef Ewald (Catonsville, Maryland); Kevin Cheung (Baltimore, Maryland) |
| ABSTRACT | Carcinomas typically invade as a cohesive multicellular unit, a process termed collective invasion. It remains unclear how different subpopulations of cancer cells contribute to this process. We developed three-dimensional (3D) organoid assays to identify the most invasive cancer cells in primary breast tumors. Collective invasion was led by specialized cancer cells that were defined by their expression of basal epithelial genes, such as cytokeratin-14 (K14) and p63. Furthermore, K14+ cells led collective invasion in the major human breast cancer subtypes. Importantly, lumenal cancer cells were observed to convert phenotypically to invasive leaders following induction of basal epithelial genes. Although only a minority of cells within lumenal tumors expressed basal epithelial genes, knockdown of either K14 or p63 was sufficient to block collective invasion. Our data reveal that heterotypic interactions between epithelial subpopulations are critical to collective invasion. We suggest that targeting the basal invasive program could limit metastatic progression. |
| FILED | Tuesday, May 13, 2014 |
| APPL NO | 14/276099 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545134 | Cosgrove |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Father Flanagan's Boys' Home (Omaha, Nebraska) |
| ASSIGNEE(S) | Father Flanagan's Boys' Home (Omaha, Nebraska) |
| INVENTOR(S) | Dominic Cosgrove (Omaha, Nebraska) |
| ABSTRACT | The present invention provides methods of treating Alport syndrome in a subject by the administration of an agent that blocks the activation of RAC1/CDC42 members of the rho family of small GTPases. Such agents include, but are not limited to, the endothelin receptor antagonists such as bosentan and letairis and neutralizing antibodies to endothelin-1. Such administration prevents invasion of the glomerular capillary tufts by mesangial lamellipodial/filopodial processes, blocks mesangial process invasion, abrogates the deposition of laminin 211 in the GBM, and prevents the activation of maladaptive expression of proteins known to contribute to glomerular disease progression. |
| FILED | Friday, June 23, 2017 |
| APPL NO | 15/631454 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/4025 (20130101) A61K 31/5377 (20130101) A61K 39/395 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5026 (20130101) Original (OR) Class G01N 33/5044 (20130101) G01N 33/6893 (20130101) G01N 2500/10 (20130101) G01N 2800/50 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545142 | Fahmy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Tarek M. Fahmy (New Haven, Connecticut); Aleksandar Vacic (Cambridge, Massachusetts); Mark A. Reed (Monroe, Connecticut) |
| ABSTRACT | The present invention relates to uniform nanostructure biosensors and methods of calibrating the response of nanostructure biosensors. The invention overcomes device to device variability that has made quantitative detection difficult. The described biosensors have uniform characteristics that allow for more reliable comparison across devices. The methods of the invention comprise normalizing the initial current rate, as measured by the nanostructure biosensor following the addition of an analyte, to device characteristics of the biosensor. The device characteristics of the biosensor which can be used to normalize the response include baseline current and transconductance, Calibration of responses allows for the generation of calibration curves for use in all devices to quantitatively detect an analyte, without the need for individual device calibration. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 15/455945 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 27/4146 (20130101) G01N 33/5438 (20130101) G01N 33/54373 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545145 | Shemesh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Or Shemesh (Sommerville, Massachusetts); Asmamaw Wassie (Cambridge, Massachusetts); Chih-Chieh Yu (Cambridge, Massachusetts); Edward Boyden (Cambridge, Massachusetts) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for imaging biological systems and physiological activity and conditions in cells. |
| FILED | Thursday, April 14, 2016 |
| APPL NO | 15/099248 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545147 | Prokunina et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Liudmila Prokunina (Rockville, Maryland); Thomas R. O'Brien (Potomac, Maryland); Brian Muchmore (Potomac, Maryland); Raymond P. Donnelly (Damascus, Maryland); Patricia A. Porter-Gill (Little Rock, Arkansas) |
| ABSTRACT | The invention is related to identification of an interferon-analog (IFNL4) protein and genetic association with spontaneous clearance of HCV infection and response to treatment for HCV infection. |
| FILED | Wednesday, May 17, 2017 |
| APPL NO | 15/597459 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/555 (20130101) C07K 16/249 (20130101) C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/707 (20130101) C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) Original (OR) Class G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545149 | Newman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gale W. Newman (Duluth, Georgia); Mike Powell (Douglasville, Georgia); Akins Doherty (Atlanta, Georgia); Chamberlain Obialo (Peachtree City, Georgia); Claudette Mitchell-Ali (Newnan, Georgia); Khalid Bashir (Dunwoody, Georgia); Mafuz Khan (Atlanta, Georgia) |
| ASSIGNEE(S) | MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia) |
| INVENTOR(S) | Gale W. Newman (Duluth, Georgia); Mike Powell (Douglasville, Georgia); Akins Doherty (Atlanta, Georgia); Chamberlain Obialo (Peachtree City, Georgia); Claudette Mitchell-Ali (Newnan, Georgia); Khalid Bashir (Dunwoody, Georgia); Mafuz Khan (Atlanta, Georgia) |
| ABSTRACT | A method for detecting HIV infection in a mammal is disclosed. The method contains the steps of isolating exosomes from a urine sample of a mammal and detecting the presence of HIV-specific biomarker in said isolated exosomes. A method for diagnosing a mammal with an HIV-associated disease, in particular, HIV-associated nephropathy is also disclosed. |
| FILED | Friday, October 02, 2009 |
| APPL NO | 12/572652 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 16/1054 (20130101) C07K 16/1063 (20130101) C07K 16/1072 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16111 (20130101) C12N 2740/16211 (20130101) C12N 2740/16311 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/40 (20130101) G01N 33/493 (20130101) G01N 33/6893 (20130101) G01N 33/56988 (20130101) Original (OR) Class G01N 2333/161 (20130101) G01N 2333/162 (20130101) G01N 2333/163 (20130101) G01N 2800/56 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545153 | Marcotte et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Edward Marcotte (Austin, Texas); Eric V. Anslyn (Austin, Texas); Andrew Ellington (Austin, Texas); Jagannath Swaminathan (Marharastra, India); Erik Hernandez (Austin, Texas); Amber Johnson (Austin, Texas); Alexander Boulgakov (Austin, Texas); James L. Bachman (Austin, Texas); Helen Seifert (Austin, Texas) |
| ABSTRACT | Identifying proteins and peptides, and more specifically large-scale sequencing of single peptides in a mixture of diverse peptides at the single molecule level is an unmet challenge in the field of protein sequencing. Herein are methods for identifying amino acids in peptides, including peptides with one or more unnatural amino acids. In one embodiment, the N-terminal amino acid is labeled with a first label and an internal amino acid is labeled with a second label. In some embodiments, the labels are fluorescent labels. In other embodiments, the internal amino acid is Lysine. In other embodiments, amino acids in peptides are identified based on the fluorescent signature for each peptide at the single molecule level. |
| FILED | Tuesday, September 15, 2015 |
| APPL NO | 15/510962 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/582 (20130101) G01N 33/6818 (20130101) G01N 33/6824 (20130101) Original (OR) Class G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545158 | Cummins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Brian Michael Cummins (Raleigh, North Carolina); Frances Smith Ligler (Raleigh, North Carolina); Glenn Walker (Raleigh, North Carolina) |
| ABSTRACT | Disclosed are methods and systems for determining concentrations of a target molecule and a variant thereof in a sample. The sample can comprise or be suspected to comprise a target molecule and at least one variant thereof and is exposed to one or more recognition elements that bind to the target molecule and/or the at least one variant. A signal is detected that is associated with the binding of the target molecule and/or a signal is detected that is associated with the binding of the at least one variant to the one or more recognition elements. The concentration of the target molecule and/or the at least one variant thereof is determined based on the signals. The system can comprise a receiver adapted to receive a sample comprising or suspected to comprise a target molecule and the at least one variant thereof, the receiver comprising one or more recognition elements that bind to one or more epitopes in the target molecule and/or the at least one variant thereof. |
| FILED | Monday, December 28, 2015 |
| APPL NO | 14/979946 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) Original (OR) Class G01N 33/6845 (20130101) G01N 2333/635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545210 | Boulant et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (St. Paul, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); Commissariat A L'Energie Atomique et Aux Energies Alternatives (Paris, France) |
| INVENTOR(S) | Nicolas Boulant (Gif-sur-Yvette, France); Pierre-Francois Van De Moortele (Minneapolis, Minnesota) |
| ABSTRACT | Systems and methods for designing RF pulses using a technique that directly controls temperature rise via a compression model that is based on virtual observation points (“VOPs”) are provided. Thermal pre-simulations are first carried out for a given RF exposure time, coil, and subject model in order to obtain complex temperature matrices, after which the compression scheme follows. As one example, the thermal model employed can be Pennes' bio-heat equation. Focusing design constraints on the temperature rise instead of the absolute temperature allows for uncertain parameters to be dropped from the thermal model, making it more robust and less prone to errors. In some embodiments, the algorithm used for RF pulse design is the active-set (“A-S”) method. |
| FILED | Tuesday, September 22, 2015 |
| APPL NO | 15/513042 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/288 (20130101) G01R 33/543 (20130101) G01R 33/5612 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545955 | Djordjevic et al. |
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| FUNDED BY |
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| APPLICANT(S) | Seven Bridges Genomics inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | SEVEN BRIDGES GENOMICS INC. (Charlestown, Massachusetts) |
| INVENTOR(S) | Dragan Djordjevic (Belgrade, Serbia); Filip Jelic (Belgrade, Serbia); Dragan Bajcic (Belgrade, Serbia); Jovan Cejovic (Belgrade, Serbia); Adam Stanojevic (Belgrade, Serbia); Milos Nesic (Belgrade, Serbia); Jelena Radenkovic (Belgrade, Serbia); Vladimir Mladenovic (Belgrade, Serbia) |
| ABSTRACT | A method for generating a query of a genomic data store includes receiving, by a query generator executing on a computing device, from a graphical user interface, an identification of a first entity of a first entity class for inclusion in a resource description framework (RDF) query. The method includes receiving from the graphical user interface, an identification of a second entity of the first entity class, the second entity having a bi-directional relationship with the first entity. The method includes automatically generating an RDF query based upon the received identification of the first entity and the received identification of the second entity. The method includes executing the RDF query to select, from a plurality of genomic data sets, at least one genomic data set for at least one patient cohort. The method includes providing a listing of genomic data sets resulting from executing the RDF query. |
| FILED | Friday, January 13, 2017 |
| APPL NO | 15/405474 |
| ART UNIT | 2159 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/248 (20190101) G06F 16/288 (20190101) G06F 16/2428 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
10546388 — Methods and systems for customizing cochlear implant stimulation and applications of same
| US 10546388 | Noble et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Jack H. Noble (Nashville, Tennessee); Rene H. Gifford (Franklin, Tennessee); Robert F. Labadie (Nashville, Tennessee); Benoit M. Dawant (Nashville, Tennessee) |
| ABSTRACT | One aspect of the invention provides a method for customizing cochlear implant stimulation of a living subject. The cochlear implant includes an electrode array having a plurality of electrodes implanted in a cochlea of the living subject. The method includes determining a position for each of the plurality of electrodes and spiral ganglion nerves that the electrode array stimulates, determining a geometric relationship between neural pathways within the cochlea and the electrode array implanted therein, and using one or more electrodes of the electrode array to stimulate a group of SG neural pathways of the cochlea based on the location of the one or more electrodes and their geometric relationship with the neural pathways. |
| FILED | Wednesday, February 15, 2017 |
| APPL NO | 15/433433 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/12 (20130101) A61B 5/4893 (20130101) A61B 6/032 (20130101) A61B 6/501 (20130101) A61B 6/5235 (20130101) A61B 34/10 (20160201) A61B 2034/104 (20160201) A61B 2034/105 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0541 (20130101) A61N 1/36185 (20130101) Image Data Processing or Generation, in General G06T 7/12 (20170101) G06T 7/30 (20170101) G06T 7/74 (20170101) Original (OR) Class G06T 7/149 (20170101) G06T 7/337 (20170101) G06T 2207/10081 (20130101) G06T 2207/20124 (20130101) G06T 2207/20128 (20130101) G06T 2207/30052 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 25/50 (20130101) H04R 25/606 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547015 | Scheuermann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | James Scheuermann (Katonah, New York); Wei Zhao (East Setauket, New York) |
| ABSTRACT | A sensor including a layer of amorphous selenium (a-Se) and at least one charge blocking layer is formed by depositing the charge blocking layer over a substrate prior to depositing the amorphous selenium, enabling the charge blocking layer to be formed at elevated temperatures. Such a process is not limited by the crystallization temperature of a-Se, resulting in the formation of an efficient charge blocking layer, which enables improved signal amplification of the resulting device. The sensor can be fabricated by forming first and second amorphous selenium layers over separate substrates, and then fusing the a-Se layers at a relatively low temperature. |
| FILED | Thursday, November 30, 2017 |
| APPL NO | 15/761187 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/241 (20130101) G01T 1/247 (20130101) G01T 1/2018 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/307 (20130101) H01L 27/308 (20130101) H01L 51/4213 (20130101) Original (OR) Class H01L 2031/0344 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10543110 | Piercy et al. |
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| FUNDED BY |
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| APPLICANT(S) | ROAM ROBOTICS INC. (San Francisco, California) |
| ASSIGNEE(S) | ROAM ROBOTICS INC. (San Francisco, California) |
| INVENTOR(S) | Brenton Piercy (San Francisco, California); Tim Swift (Albany, California); Giancarlo Nucci (San Francisco, California); Callum Lamb (San Bruno, California); Pete Lynn (Oakland, California); Saul Griffith (San Francisco, California); Leanne Luce (San Francisco, California) |
| ABSTRACT | A lower-leg exoskeleton including an inflatable actuator that is configured to be worn over a front portion of a foot of a user; a rigid foot structure coupled to the inflatable actuator that is configured to surround a portion of a foot of the user; and a rigid shin structure coupled to the inflatable actuator and configured to engage the shin of the user. When worn by a user, the lower-leg exoskeleton can receive and transmit an actuator load generated by the inflatable actuator to a load contact point defined by the rigid foot structure which is forward of the heel of a user. Inflation of the inflatable actuator can generate a moment about the ankle of a user to cause flexion of the foot of the user. |
| FILED | Monday, March 28, 2016 |
| APPL NO | 15/082824 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/60 (20130101) A61F 2/68 (20130101) Original (OR) Class A61F 2002/74 (20130101) A61F 2002/501 (20130101) A61F 2002/745 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543518 | Ball |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OXYTEC LLC (Newton, Massachusetts) |
| ASSIGNEE(S) | Oxytec LLC (Newton, Massachusetts) |
| INVENTOR(S) | Raymond G. Ball (Newton, Massachusetts) |
| ABSTRACT | A method and system for the reduction of contamination in soil and groundwater is provided. Cyclic oligosaccharides can be used, for example, to carry oxidants, carry activators, solubilize organic contaminants and promote biodegradation. |
| FILED | Wednesday, January 24, 2018 |
| APPL NO | 15/878953 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/24 (20130101) Reclamation of Contaminated Soil B09C 1/002 (20130101) B09C 1/02 (20130101) B09C 1/08 (20130101) Original (OR) Class B09C 2101/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/72 (20130101) C02F 1/78 (20130101) C02F 1/725 (20130101) C02F 2101/38 (20130101) C02F 2101/306 (20130101) C02F 2101/322 (20130101) C02F 2101/327 (20130101) C02F 2101/363 (20130101) C02F 2101/366 (20130101) C02F 2103/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543893 | Reeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lynntech, Inc. (College Station, Texas) |
| ASSIGNEE(S) | Lynntech, Inc. (College Station, Texas) |
| INVENTOR(S) | Jonathan Reeh (College Station, Texas); Jady Stevens (Bryan, Texas); Tiffany Jefferson (Bryan, Texas); Justin McIntire (Bryan, Texas); Chris Hadley (Bryan, Texas); John Zbranek (College Station, Texas); Jeffrey S. Parkey (College Station, Texas); Ashwin Kumar Balasubramanian (College Station, Texas); Jibi Varughese (College Station, Texas); Geoffrey D. Hitchens (Allen, Texas); Marc W. Penny (Bryan, Texas) |
| ABSTRACT | The present invention includes an underwater vehicle power unit and method of operating the same comprising: a fuel and waste stack comprising one or more reactant or fuel storage bladders and one or more waste storage bladders; a heater; a reactor that generates hydrogen and waste; a hydrogen and waste separator; a back-pressure regulator; a hydrogen and liquid separator; a fuel cell; and a controller that controls the temperature of the heater, the flow of fuel into the reactor, the flow of hydrogen into the fuel cell, the flow of water that dilutes the fuel, the flow of waste from the reactor and/or the fuel cell into the one or more waste storage bladders. |
| FILED | Friday, May 18, 2018 |
| APPL NO | 15/983384 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/08 (20130101) Original (OR) Class Marine Propulsion or Steering B63H 21/00 (20130101) B63H 21/383 (20130101) B63H 2021/003 (20130101) Auxiliaries on Vessels B63J 4/006 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/065 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/065 (20130101) H01M 8/04007 (20130101) H01M 8/04029 (20130101) H01M 8/04141 (20130101) H01M 8/04216 (20130101) H01M 8/04753 (20130101) H01M 8/04761 (20130101) H01M 8/04776 (20130101) H01M 2250/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543897 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Jonathan K. Brown (Kent, Washington); Glenn Scott Bushnell (Puyallup, Washington); Dan J. Clingman (Milton, Washington) |
| ABSTRACT | There is provided a training system capable of performing work. The system has a shape memory alloy (SMA) actuator exhibiting a generally planar transformational behavior. The system further has one or more heating elements for transforming the SMA actuator from an original shape to a trained shape, thereby performing work. |
| FILED | Monday, April 03, 2017 |
| APPL NO | 15/477986 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 37/045 (20130101) Aeroplanes; Helicopters B64C 1/065 (20130101) B64C 3/44 (20130101) B64C 3/185 (20130101) Original (OR) Class B64C 27/72 (20130101) B64C 27/473 (20130101) B64C 2001/0081 (20130101) B64C 2027/7211 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/006 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543914 | Darrow, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | David A. Darrow, Jr. (Stratford, Connecticut); Frank P. D'Anna (Seymour, Connecticut) |
| ABSTRACT | A rotor blade configured to fold about a blade fold axis includes a first section and a second section. The first section is configured to mount to a rotor hub and includes a first connector having at least one first opening. The second section includes a second connector having at least one second opening. The second section is rotatably coupled to the first section and is configured to rotate about the blade fold axis between an aligned position and a rotated position. A linkage is operably coupled to the first section and the second section. The linkage includes a plurality of links loosely connected such that the linkage is configured to support the second section of the rotor blade only when the second section is in the rotated position. |
| FILED | Thursday, March 27, 2014 |
| APPL NO | 14/915147 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/10 (20130101) B64C 27/50 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544265 | Palmese et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Giuseppe R. Palmese (Hainesport, New Jersey); James Throckmorton (Rochester, New York) |
| ASSIGNEE(S) | DREXEL UNIVERSITY (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Giuseppe R. Palmese (Hainesport, New Jersey); James Throckmorton (Rochester, New York) |
| ABSTRACT | The invention relates to the use of dicyanamide-containing ionic liquids which decrease the cure temperature of cyanate esters to form unique thermoset polymers having a triazine network. These thermoset polymers having the triazine network have an ionic character allowing for use in varied applications. The thermoset polymers described herein are useful in high temperature performance composites, and their high Tg makes them useful as a substitute for epoxies in the microelectronics industry. The thermoset polymers have good fracture toughness, excellent substrate adhesion, low shrinkage, and low moisture uptake. |
| FILED | Friday, January 29, 2016 |
| APPL NO | 15/543550 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/0644 (20130101) C08G 73/0661 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544312 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Shaoyi Jiang (Redmond, Washington); Yuting Li (Seattle, Washington); Hong Xue (Pleasanton, California); Shengfu Chen (Hangzhou, China PRC) |
| ABSTRACT | Marine coatings including cationic polymers hydrolyzable to nonfouling zwitterionic polymers, coated marine surfaces, and methods for making and using the marine coatings. |
| FILED | Thursday, December 29, 2016 |
| APPL NO | 15/394538 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/785 (20130101) Ships or Other Waterborne Vessels; Equipment for Shipping B63B 59/04 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/16 (20130101) C09D 5/165 (20130101) C09D 5/1606 (20130101) C09D 5/1637 (20130101) Original (OR) Class C09D 5/1656 (20130101) C09D 5/1662 (20130101) C09D 5/1668 (20130101) C09D 5/1675 (20130101) C09D 133/26 (20130101) C09D 151/085 (20130101) C09D 153/00 (20130101) C09D 183/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/3154 (20150401) Y10T 428/31511 (20150401) Y10T 428/31551 (20150401) Y10T 428/31663 (20150401) Y10T 428/31725 (20150401) Y10T 428/31786 (20150401) Y10T 428/31844 (20150401) Y10T 428/31938 (20150401) Y10T 428/31942 (20150401) Y10T 442/10 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544421 | Cheung |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New York Structural Biology Center (New York, New York) |
| ASSIGNEE(S) | New York Structural Biology Center (New York, New York) |
| INVENTOR(S) | Jonah Cheung (Brooklyn, New York) |
| ABSTRACT | A system and method for creating crystals from human acetylcholinesterase. The crystals can then be analyzed using X-ray crystallography. A segment of DNA for human acetylcholinesterase is isolated that includes the codon sequence GAGGGC. A polyhistidine tag is inserted between codon GAG and codon GGC to produce a recombinant acetylcholinesterase construct. The recombinant acetylcholinesterase construct is used to transfect cells on a prepared growth medium. The growing cells secrete a portion of the recombinant acetylcholinesterase construct. The secreted portion is concentrated and the tag cleaved. The concentrate is then buffered and used to form crystals. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 15/469227 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6421 (20130101) C12N 15/66 (20130101) Original (OR) Class C12N 15/1031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544496 | Yan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Jiayi Yan (Tianjin, China PRC); Gregory B. Olson (Riverwoods, Illinois) |
| ABSTRACT | A near-α transformation-induced plasticity (TRIP) titanium (Ti) alloy is designed by using a thermodynamic database and a mobility database of Ti alloys for α, β, and Ti3Al phase equilibria and diffusive processes; based on experimental data, creating a thermodynamic and kinetic database for β-to-α′/α″ martensitic transformations in the Ti alloys; creating a molar volume database for the β-to-α′/α″ martensitic transformations in the Ti alloys at room temperature; and obtaining an overall composite of the near-α TRIP Ti alloy by adjusting a reference overall composite of a reference near-α Ti alloy based on the created thermodynamic database, where the reference near-α Ti alloy is Ti-5Al-1Sn-1Zr-1V-0.8Mo-0.1Si-0.1Fe-0.1O by weight percentage (Ti-5111), and wherein the near-α TRIP Ti alloy is Ti-8Al-1V-1Sn-1Zr-0.6Mo-0.9Fe-0.1Si-0.1O by weight percentage. |
| FILED | Wednesday, July 18, 2018 |
| APPL NO | 16/038527 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 14/00 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/183 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544693 | Nasir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| INVENTOR(S) | Shakeel Nasir (Torrance, California); John Schugardt (Chandler, Arizona); Justin Brown (Phoenix, Arizona); Cristopher Frost (Scottsdale, Arizona) |
| ABSTRACT | Provided is a radial diffuser that includes a housing, a plurality of diffuser vanes, and a plurality of deswirl vanes and at least one vane extension providing a service routing. Each of the vane extensions is disposed after a radial section and may extend into or through a transition and into the deswirl cascade. At least a portion of the vane extensions include a service passage extending therethrough. Each service passage is configured to allow a service conduit to extend therethrough without adversely crossing either a diffusion flow passage or a transition flow passage. |
| FILED | Wednesday, June 15, 2016 |
| APPL NO | 15/183274 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 9/065 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Non-positive-displacement Pumps F04D 17/025 (20130101) F04D 29/284 (20130101) F04D 29/321 (20130101) F04D 29/441 (20130101) F04D 29/444 (20130101) F04D 29/522 (20130101) F04D 29/542 (20130101) F04D 29/4206 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/35 (20130101) F05D 2240/129 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545012 | Sowle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zak Sowle (Bellbrook, Ohio); Srikanth Vasudevan (Monroe, Connecticut); Matthew C. Birch (Madison, Alabama) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Zak Sowle (Bellbrook, Ohio); Srikanth Vasudevan (Monroe, Connecticut); Matthew C. Birch (Madison, Alabama) |
| ABSTRACT | A projectile incorporates one or more spoiler-tabbed spinning disks to effect flow around the projectile and thus impart steering forces and/or moments. The spoiler tabs may be deployed only during steering phases of travel thus minimizing the drag penalty associated with steering systems. The disks are driven by motors and informed and controlled by sensors and electronic control systems. The spoiler tabs protrude through the surface of the projectile only for certain angles of spin of the spinning disk. For spin-stabilized projectiles, the disks spin at substantially the same rate as the projectile, but the disks may function in fin-stabilized projectiles as well. Any number of such spinning flow effector disks may be incorporated in a projectile, with the manner of functional coordination differing slightly for even and odd numbers of disks. |
| FILED | Thursday, December 27, 2018 |
| APPL NO | 16/233484 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 13/00 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/00 (20130101) F42B 10/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545058 | Bao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Zhenan Bao (Stanford, California); Stefan Christian Bernhardt Mannsfeld (Cameron Park, California); Jason Locklin (Bogart, Georgia); Chee-Keong Tee (Stanford, California) |
| ABSTRACT | Sensors, sensing arrangements and devices, and related methods are provided. In accordance with an example embodiment, an impedance-based sensor includes a flexible dielectric material and generates an output based on pressure applied to the dielectric material and a resulting compression thereof. In certain embodiments, the dielectric material includes a plurality of regions separated by gaps and configured to elastically deform and recover in response to applied pressure. |
| FILED | Monday, March 07, 2016 |
| APPL NO | 15/062841 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/146 (20130101) Original (OR) Class G01L 1/148 (20130101) Electric Digital Data Processing G06F 3/044 (20130101) G06F 3/0412 (20130101) G06F 3/0414 (20130101) G06F 2203/04102 (20130101) G06F 2203/04103 (20130101) G06F 2203/04107 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/84 (20130101) H01L 51/0055 (20130101) H01L 51/0541 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49002 (20150115) Y10T 156/10 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545069 | Wiese et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Connor Wiese (Adrian, Michigan); Kurt Rouser (Monument, Colorado) |
| ABSTRACT | A cascade wind tunnel T-bar turbulence generating grid for creating a turbulence intensity in an air flow having an air flow volume for testing at least two turbine blades having a turbine blade dimension and a pitchwise location, the turbulence generating grid comprising a plurality of cross bars having a front surface and a cross bar gap, a plurality of vertical bars having a vertical bar front surface and a cross bar gap and at least two support bars assembled to form a plurality of air flow. The support bar at an angle θ to the air flow and about parallel to the turbine blades. The cross bars mounted to the support bar such that the cross bar front surface is perpendicular to the air flow. The vertical bars are mounted to the support bar such that the vertical bar front surface is perpendicular to the air flow and wherein the vertical bar gap and a horizontal gap provide the turbulence intensity about constant across the pitchwise location. |
| FILED | Thursday, January 28, 2016 |
| APPL NO | 15/009210 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 2005/0025 (20130101) B01F 2215/0037 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/00 (20130101) F15D 1/0005 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 9/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545093 | Swager et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy M. Swager (Newton, Massachusetts); Joseph M. Azzarelli (Cambridge, Massachusetts); Kathleen R. White (Dubuque, Iowa) |
| ABSTRACT | A detector can detect an analyte including a carbon-carbon multiple bond moiety and capable of undergoing Diels-Alder reaction with a heteroaromatic compound having an extrudable group. The detector can detect, differentiate, and quantify ethylene. |
| FILED | Friday, April 04, 2014 |
| APPL NO | 14/246008 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545133 | Ewald et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Andrew Josef Ewald (Catonsville, Maryland); Kevin Cheung (Baltimore, Maryland) |
| ABSTRACT | Carcinomas typically invade as a cohesive multicellular unit, a process termed collective invasion. It remains unclear how different subpopulations of cancer cells contribute to this process. We developed three-dimensional (3D) organoid assays to identify the most invasive cancer cells in primary breast tumors. Collective invasion was led by specialized cancer cells that were defined by their expression of basal epithelial genes, such as cytokeratin-14 (K14) and p63. Furthermore, K14+ cells led collective invasion in the major human breast cancer subtypes. Importantly, lumenal cancer cells were observed to convert phenotypically to invasive leaders following induction of basal epithelial genes. Although only a minority of cells within lumenal tumors expressed basal epithelial genes, knockdown of either K14 or p63 was sufficient to block collective invasion. Our data reveal that heterotypic interactions between epithelial subpopulations are critical to collective invasion. We suggest that targeting the basal invasive program could limit metastatic progression. |
| FILED | Tuesday, May 13, 2014 |
| APPL NO | 14/276099 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545153 | Marcotte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Edward Marcotte (Austin, Texas); Eric V. Anslyn (Austin, Texas); Andrew Ellington (Austin, Texas); Jagannath Swaminathan (Marharastra, India); Erik Hernandez (Austin, Texas); Amber Johnson (Austin, Texas); Alexander Boulgakov (Austin, Texas); James L. Bachman (Austin, Texas); Helen Seifert (Austin, Texas) |
| ABSTRACT | Identifying proteins and peptides, and more specifically large-scale sequencing of single peptides in a mixture of diverse peptides at the single molecule level is an unmet challenge in the field of protein sequencing. Herein are methods for identifying amino acids in peptides, including peptides with one or more unnatural amino acids. In one embodiment, the N-terminal amino acid is labeled with a first label and an internal amino acid is labeled with a second label. In some embodiments, the labels are fluorescent labels. In other embodiments, the internal amino acid is Lysine. In other embodiments, amino acids in peptides are identified based on the fluorescent signature for each peptide at the single molecule level. |
| FILED | Tuesday, September 15, 2015 |
| APPL NO | 15/510962 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/582 (20130101) G01N 33/6818 (20130101) G01N 33/6824 (20130101) Original (OR) Class G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545200 | Barry et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | John Francis Barry (Cambridge, Massachusetts); Jennifer May Schloss (Cambridge, Massachusetts); Matthew James Turner (Somerville, Massachusetts); Mikael Paul Backlund (Cambridge, Massachusetts); Ronald Walsworth (Newton, Massachusetts) |
| ABSTRACT | A system and method for performing vector magnetometry are described. A method can include illuminating diamond with a modulated optical signal and a modulated microwave (MW) signal. A first, bias magnetic field is also applied to the diamond. Light emitted from the diamond in response to the optical signal, the MW signal, and the first magnetic field is detected via a single detector at a fixed position relative to the diamond. A modulation of the detected light encodes information corresponding to a plurality of nitrogen vacancy (NV) axes of the diamond. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 16/307850 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) Original (OR) Class G01R 33/032 (20130101) G01R 33/0041 (20130101) G01R 33/1215 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545461 | Roper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Christopher S. Roper (Oak Park, California); Adam F. Gross (Santa Monica, California); Matthew T. Rakher (Oxnard, California); Logan D. Sorenson (Agoura Hills, California); John J. Vajo (West Hills, California); Jason A. Graetz (Calabasas, California); Russell Mott (Calabasas, California); Danny Kim (Agoura Hills, California) |
| ABSTRACT | Some variations provide an alkali metal or alkaline earth metal vapor cell with a solid ionic conductor and intercalable-compound electrodes. The intercalable-compound electrodes are used as efficient sources and/or as sinks for alkali metal or alkaline earth metal atoms, thus enabling electrical control over metal atom content in the vapor cell. Some variations provide a vapor-cell system comprising: a vapor-cell region configured to allow a vapor-cell optical path into a vapor-cell vapor phase; a first electrode containing an intercalable compound capable of being intercalated by at least one element selected from Rb, Cs, Na, K, or Sr; a second electrode electrically isolated from the first electrode; and an ion-conducting layer between the first electrode and the second electrode. The ion-conducting layer is ionically conductive for at least one ionic species selected from Rb+, Cs+, Na+, K+, or Sr2+. The first intercalable compound is preferably a carbonaceous material, such as graphite. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/639391 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 26/10 (20130101) Time-interval Measuring G04F 5/145 (20130101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/06 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546063 | Beller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles E. Beller (Baltimore, Maryland); Chengmin Ding (Chantilly, Virginia); Allen Ginsberg (St. Petersburg, Florida); Elinna Shek (Herndon, Virginia) |
| ABSTRACT | Natural language processing of raw text data for optimal sentence boundary placement. Raw text is extracted from a document and subject to cleaning. The extracted raw text is examined to identify preliminary sentence boundaries, which are used to identify potential sentences in the raw text. One or more potential sentences are assigned a well-formedness score. A value of the score correlates to whether the potential sentence is a truncated/ill-formed sentence or a well-formed sentence. One or more preliminary sentence boundaries are optimized depending on the value of the score of the potential sentence(s). Accordingly, the processing herein is an optimization that creates a sentence boundary optimized output. |
| FILED | Tuesday, December 13, 2016 |
| APPL NO | 15/376942 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 17/24 (20130101) G06F 17/274 (20130101) G06F 17/277 (20130101) G06F 17/2775 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546116 | Sahin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Cem S Sahin (Concord, Massachusetts); Robert D. Lychev (Cambridge, Massachusetts); Neal Wagner (Burlington, Massachusetts) |
| ABSTRACT | A password evaluation engine used to evaluate a user's password that redefines the concepts of password complexity and password strength is discussed. Password complexity may be calculated by the evaluation engine so as to take into account the amount of knowledge possessed by a potential attacker, seeking to crack the password, of the rules corresponding to a rule set used for generating the password. A determination of password strength by the evaluation engine may consider a potential attacker's computational resources, the protection function used to protect/store a password and the amount of time available to the attacker to crack the password with respect to an identified search space based on the attacker's knowledge. Embodiments also enable a password strength estimator to be evaluated and policy recommendations to be generated for an entity's password policy requirements. |
| FILED | Friday, December 16, 2016 |
| APPL NO | 15/381493 |
| ART UNIT | 2494 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/31 (20130101) G06F 21/31 (20130101) G06F 21/46 (20130101) Original (OR) Class G06F 21/55 (20130101) G06F 21/577 (20130101) G06F 21/604 (20130101) G06F 2221/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0863 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546130 | Chaney |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Richard R Chaney (Tipp City, Ohio) |
| ABSTRACT | A Timed Attestation Process (TAP) utilizes a CPU bus cycle counter/timer to accurately measure the time needed to calculate a specific function value for an attestation query in an embedded system. The attestation query takes into account embedded software and the hardware data path. An attestation value database stores the unique timing and function data associated with each hardware design element in the embedded device, which each have unique timing characteristics. By utilizing the CPU bus cycle counter/timer of the client device, the TAP increases the time accuracy to the smallest tolerance possible relative to a particular CPU (typically +/−one instruction cycle). The integrity of the embedded software contained in the permanent storage elements and the hardware timing to access each component is verifiable against the unique timing characteristics stored in the database. With this timing characteristic, each hardware element is linked to a specific software configuration. |
| FILED | Friday, February 24, 2017 |
| APPL NO | 15/441675 |
| ART UNIT | 2434 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2477 (20190101) G06F 21/57 (20130101) Original (OR) Class G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546417 | Black et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Michael J. Black (Providence, Rhode Island); Alexandru O. Balan (Pawtucket, Rhode Island); Alexander W. Weiss (Shirley, Massachusetts); Leonid Sigal (Pittsburgh, Pennsylvania); Matthew M. Loper (Providence, Rhode Island); Timothy S. St. Clair (Cambridge, Massachusetts) |
| ABSTRACT | A system and method of estimating the body shape of an individual from input data such as images or range maps. The body may appear in one or more poses captured at different times and a consistent body shape is computed for all poses. The body may appearin minimal tight-fitting clothing or in normal clothing wherein the described method produces an estimate of the body shape under the clothing. Clothed or bare regions of the body are detected via image classification and the fitting method is adapted to treat each region differently. Body shapes are represented parametrically and are matched to other bodies based on shape similarity and other features. Standard measurements are extracted using parametric or non-parametric functions of body shape. The system components support many applications in body scanning, advertising, social networking, collaborative filtering and Internet clothing shopping. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 16/453135 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00369 (20130101) G06K 9/6221 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0601 (20130101) Image Data Processing or Generation, in General G06T 7/75 (20170101) G06T 7/77 (20170101) G06T 17/00 (20130101) Original (OR) Class G06T 2207/10028 (20130101) G06T 2207/30196 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546418 | Barré et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Brent Barré (Metarie, Louisiana); Elias Ioup (New Orleans, Louisiana); John Sample (Pearl River, Louisiana) |
| ABSTRACT | Embodiments relate to visualization of positional geospatial uncertainty. Initially, a map image request for geographic features is received from a client computing device, where the map image request includes an uncertainty type, a distribution shape, and a selected visualization technique. An uncertainty buffer pixel size is determined based on a geographic distance covered by the distribution shape. At this stage, an uncertainty buffer of the uncertainty buffer pixel size is iterated across, and uncertainty is rendered at each position along the uncertainty buffer by determining a corresponding distribution probability from a probability distribution function at a current pixel position, mapping the corresponding distribution probability to a corresponding visual value of the selected visualization technique, rendering an uncertainty feature for the corresponding distribution probability around the geographic feature at the current pixel position and according to the corresponding visual value; and advancing the current pixel position based on the uncertainty type. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 15/799150 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/62 (20170101) G06T 7/143 (20170101) G06T 11/001 (20130101) G06T 17/05 (20130101) Original (OR) Class G06T 2207/10032 (20130101) G06T 2207/20076 (20130101) G06T 2207/30181 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546703 | Joo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | James J. Joo (Centerville, Ohio) |
| ABSTRACT | A switch mechanism has a compliant buckling bar that includes a single fixed end mounted to a mounting surface and a free end that is displaced with respect to the fixed end. The mounting of the fixed end to the mounting surface may constitute the only fixed connection between the bar and the mounting surface. The bar moves between two stable positions in response to a transition force applied transversely to the free end. Residual stress in the bar may be higher when the free end is at each of the stable positions than when the free end is at a neutral position located between the stable positions. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 15/899467 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 3/46 (20130101) H01H 5/18 (20130101) H01H 13/38 (20130101) H01H 21/44 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546734 | Youngner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Daniel Youngner (Maple Grove, Minnesota) |
| ABSTRACT | Apparatuses, systems, and methods for ion traps are described herein. One apparatus includes a number of microwave (MW) rails and a number of radio frequency (RF) rails formed with substantially parallel longitudinal axes and with substantially coplanar upper surfaces. The apparatus includes two sequences of direct current (DC) electrodes with each sequence formed to extend substantially parallel to the substantially parallel longitudinal axes of the MW rails and the RF rails. The apparatus further includes a number of through-silicon vias (TSVs) formed through a substrate of the ion trap and a trench capacitor formed in the substrate around at least one TSV. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 16/399568 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546990 | Schwede et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Spark Thermionics, Inc. (Berkeley, California) |
| ASSIGNEE(S) | Spark Thermonics, Inc. (Berkeley, California) |
| INVENTOR(S) | Jared William Schwede (Berkeley, California); Lucas Heinrich Hess (Berkeley, California) |
| ABSTRACT | A thermionic energy converter, preferably including an anode and a cathode. An anode of a thermionic energy converter, preferably including an n-type semiconductor, one or more supplemental layers, and an electrical contact. A method for work function reduction and/or thermionic energy conversion, preferably including inputting thermal energy to a thermionic energy converter, illuminating an anode of the thermionic energy converter, thereby preferably reducing a work function of the anode, and extracting electrical power from the system. |
| FILED | Wednesday, December 12, 2018 |
| APPL NO | 16/218032 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 45/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/14 (20130101) H01L 35/18 (20130101) H01L 35/22 (20130101) H01L 35/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546994 | Dial et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Oliver Dial (Yorktown Heights, New York); Jay M. Gambetta (Yorktown Heights, New York); Douglas T. McClure, III (Rye, New York); Matthias Steffen (Cortlandt Manor, New York) |
| ABSTRACT | A technique relates a superconducting microwave cavity. An array of posts has different heights in the cavity, and the array supports a localized microwave mode. The array of posts includes lower resonant frequency posts and higher resonant frequency posts. The higher resonant frequency posts are arranged around the lower resonant frequency posts. A first plate is opposite a second plate in the cavity. One end of the lower resonant frequency posts is positioned on the second plate so as to be electrically connected to the second plate. Another end of the lower resonant frequency posts in the array is open so as not to form an electrical connection to the first plate. Qubits are connected to the lower resonant frequency posts in the array of posts, such that each of the qubits is physically connected to one or two of the lower resonant frequency posts in the array of posts. |
| FILED | Tuesday, August 28, 2018 |
| APPL NO | 16/114797 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) G06N 20/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/14 (20130101) H01L 39/24 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546997 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Delin Zhang (Saint Paul, Minnesota) |
| ABSTRACT | Articles including a fixing layer and a free layer including a layer including an FePd alloy. The free layer may include a composite layer including a perpendicular synthetic antiferromagnetic (p-SAF) structure. Techniques for forming and using articles including FePd alloy layers or p-SAF structures. Example articles and techniques may be usable for storage and logic devices. |
| FILED | Friday, December 01, 2017 |
| APPL NO | 15/829134 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/18 (20130101) G11C 11/161 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 43/04 (20130101) H01L 43/06 (20130101) H01L 43/08 (20130101) H01L 43/10 (20130101) Original (OR) Class H01L 43/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547105 | Logan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John T. Logan (Alexandria, Virginia); Rick W. Kindt (Arlington, Virginia) |
| ABSTRACT | Systems and methods are provided for enhancing the electrical performance of ultra-wideband (UWB) electronically scanned arrays (ESA) for use in multifunctional, electronic warfare, communications, radar, and sensing systems. Embodiments of the present disclosure provide designed metal and dielectric elements placed above the arbitrary radiator (i.e., in the superstrate region) to simultaneously aid impedance and polarization challenges. These elements can be compatible with arbitrary antenna element types. |
| FILED | Friday, March 02, 2018 |
| APPL NO | 15/910714 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/523 (20130101) Original (OR) Class H01Q 21/0025 (20130101) H01Q 21/062 (20130101) H01Q 21/064 (20130101) H01Q 25/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547117 | Tomasic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Unites States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Boris Tomasic (Harvard, Massachusetts); Carl R. Pfeiffer (Beavercreek, Ohio); Thomas P. Steffen (Xenia, Ohio) |
| ABSTRACT | An active electronically scanned array (AESA) is disclosed. The AESA includes a linear-to-circular polarizer coupled to a radiating aperture and one or more transmit-receive modules coupled to radiating elements and a liquid cooling manifold having a plurality of distributed liquid cooling ducts disposed adjacent the one or more transmit-receive modules to provide cooling of the AESA during high-power operation. |
| FILED | Tuesday, November 27, 2018 |
| APPL NO | 16/201181 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 15/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547200 | Abidi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Asad A. Abidi (Los Angeles, California); Jiacheng Pan (Los Angeles, California) |
| ABSTRACT | Wireless power transfer systems in accordance with embodiments of the invention are disclosed. In one embodiment, a wireless power transfer system includes a power transmitter driven by an oscillator, a power receiver including a resistive load, and a coupled resonator link configured to deliver power from a transmitter tank circuit to a receiver tank circuit, wherein the free-running oscillator automatically tunes to oscillate at a frequency that does not experience a phase shift due to the impedance of the transmit side of the coupled resonator link, wherein the power transmitter provides regulated voltage across a range of distances between the transmitter tank circuit and the receiver tank circuit, and wherein the power transmitter regulates voltage across a range of resistive loads of the power receiver. |
| FILED | Friday, June 02, 2017 |
| APPL NO | 15/612893 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 7/045 (20130101) Original (OR) Class H02J 50/12 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547679 | Burnett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Eden Prairie, Minnesota) |
| ASSIGNEE(S) | Architecture Technology Corporation (Eden Prairie, Minnesota) |
| INVENTOR(S) | Benjamin L. Burnett (Prior Lake, Minnesota); Ranga S. Ramanujan (Eden Prairie, Minnesota) |
| ABSTRACT | Disclosed herein are embodiments of a cloud data synchronization system enabling an user operating a mobile client device to download mission-specific data sets from a fixed cloud-based server system to a database of the mobile client device, and then use the downloaded data sets independently on the mobile client device when the mobile client device is disconnected from a network connecting to the fixed cloud-based server system. When connectivity to the fixed cloud-based server system is re-established by the mobile client device in an intermittent and bandwidth-limited communication network environment, the fixed cloud-based server system may provide bi-directional data synchronization between records of the fixed cloud-based server system and the mobile client device to update the data sets on the fixed cloud-based server system and the mobile client device while operating in the intermittent and bandwidth-limited communication network environment. |
| FILED | Tuesday, January 02, 2018 |
| APPL NO | 15/860431 |
| ART UNIT | 2457 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/42 (20130101) H04L 67/1095 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548210 | Eden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | J. Gary Eden (Champaign, Illinois); Paul V. Braun (Savoy, Illinois); Sung-Jin Park (Champaign, Illinois); Hee Jun Yang (Urbana, Illinois); Peng Sun (Urbana, Illinois); Runyu Zhang (Urbana, Illinois) |
| ABSTRACT | Non-disperse, periodic microplasmas are generated in a volume lacking interfering structures, such as electrodes, to enable photonic interaction between incident electromagnetic energy and the non-disperse, periodic microplasmas. Preferred embodiments leverage 1D, 2D, 3D and super 3D non-disperse, periodic microplasmas. In preferred embodiments, the non-disperse, periodic microplasmas are elongate columnar microplasmas. In other embodiments, the non-disperse, periodic microplasmas are discrete isolated microplasmas. The photonic properties can change by selectively activating groups of the periodic microplasmas. |
| FILED | Wednesday, September 28, 2016 |
| APPL NO | 15/279057 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/24 (20130101) H05H 1/2406 (20130101) Original (OR) Class H05H 2001/2412 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10543456 | Baxter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Larry Baxter (Orem, Utah); Christopher Hoeger (Provo, Utah); Stephanie Burt (Provo, Utah); Kyler Stitt (Lindon, Utah); Eric Mansfield (Spanish Fork, Utah); Aaron Sayre (Spanish Fork, Utah); David Frankman (Provo, Utah); Andrew Baxter (Spanish Fork, Utah); Nathan Davis (Bountiful, Utah) |
| ASSIGNEE(S) | Hall Labs LLC (Provo, Utah) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); Christopher Hoeger (Provo, Utah); Stephanie Burt (Provo, Utah); Kyler Stitt (Lindon, Utah); Eric Mansfield (Spanish Fork, Utah); Aaron Sayre (Spanish Fork, Utah); David Frankman (Provo, Utah); Andrew Baxter (Spanish Fork, Utah); Nathan Davis (Bountiful, Utah) |
| ABSTRACT | A process for forming a solid product or products is disclosed. The process is provided with n desublimating exchangers. An exchanger E1 being associated with a first exchanger and an exchanger En being associated with an nth exchanger, n representing the number of exchangers. The n exchangers comprise at least one direct-contact exchanger comprising a contact fluid. A process fluid is passed through the n exchangers in order from E1 through En. The process fluid comprises a product component or components. The solid product or products form from the product component or components in the plurality of exchangers by desublimation. The solid product or products are separated from the process fluid. In this manner, a solid product or products is formed. |
| FILED | Monday, April 24, 2017 |
| APPL NO | 15/495217 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 53/002 (20130101) B01D 53/265 (20130101) Original (OR) Class B01D 2256/16 (20130101) B01D 2256/20 (20130101) B01D 2256/24 (20130101) B01D 2256/245 (20130101) B01D 2257/80 (20130101) B01D 2257/302 (20130101) B01D 2257/304 (20130101) B01D 2257/404 (20130101) B01D 2257/408 (20130101) B01D 2257/504 (20130101) B01D 2257/602 (20130101) B01D 2257/702 (20130101) B01D 2258/0283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544052 | Subban et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); Chinmayee V. Subban (Hayward, California); Ashok J. Gadgil (El Cerrito, California); Robert Kostecki (Lafayette, California); Guoying Chen (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Chinmayee V. Subban (Hayward, California); Ashok J. Gadgil (El Cerrito, California); Robert Kostecki (Lafayette, California); Guoying Chen (Oakland, California) |
| ABSTRACT | The present invention provides for a device useful or removing dissolved ions from water comprising or configured to comprise composite resin electrodes. The present invention provides for a device useful for removing dissolved ions from water comprising or configured to comprise composite resin electrodes. The present invention also provides for a method for removing dissolved ions from water comprising providing said device, and using it thereof. |
| FILED | Monday, October 05, 2015 |
| APPL NO | 15/515999 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/42 (20130101) C02F 1/4604 (20130101) C02F 1/4691 (20130101) Original (OR) Class C02F 2001/46138 (20130101) C02F 2001/46157 (20130101) C02F 2101/14 (20130101) C02F 2101/103 (20130101) C02F 2103/06 (20130101) C02F 2103/08 (20130101) C02F 2303/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544058 | Ewsuk |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Kevin G. Ewsuk (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to glass composites, including filled glass composites and uses thereof. In particular examples, the composites provide improved thermal expansion characteristics. Also described are methods of forming such composites, such as by adding a particle filler to a glass mixture. |
| FILED | Thursday, May 31, 2018 |
| APPL NO | 15/993889 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 32/02 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/097 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544168 | Beard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Colorado School of Mines (Golden, Colorado); The Regents of the university of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Colorado School of Mines (Golden, Colorado); The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Matthew C. Beard (Arvada, Colorado); Daniel McCray Kroupa (Denver, Colorado); Alan Sellinger (Golden, Colorado) |
| ABSTRACT | An aspect of the present disclosure is a nanocrystal that includes a nanocrystal core and a ligand coordinated to a surface of the nanocrystal core, where the ligand includes a functionalized aromatic molecule. In some embodiments of the present disclosure, the functionalized aromatic molecule may include at least one of cinnamic acid (CAH) and/or a functionalized CAH molecule. |
| FILED | Thursday, June 15, 2017 |
| APPL NO | 15/623910 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/003 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/50 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/188 (20130101) C09K 2211/1007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544195 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Kimberly Brown (Elk Grove, California); Paul Harris (Carnation, Washington); Elizabeth Zaretsky (Reno, Nevada); Edward Re (Davis, California); Elena Vlasenko (Davis, California); Keith McFarland (Davis, California); Alfredo Lopez de Leon (Davis, California) |
| ABSTRACT | The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides. |
| FILED | Wednesday, October 10, 2018 |
| APPL NO | 16/156251 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/37 (20130101) Original (OR) Class Detergent Compositions; Use of Single Substances as Detergents; Soap or Soap-making; Resin Soaps; Recovery of Glycerol C11D 3/38645 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 1/14 (20130101) C12N 1/16 (20130101) C12N 1/20 (20130101) C12N 9/2437 (20130101) C12N 9/2445 (20130101) C12N 15/52 (20130101) C12N 15/63 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/14 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2201/00 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 302/01021 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544726 | Kurtz |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ford Global Technologies, LLC (Dearborn, Michigan) |
| ASSIGNEE(S) | Ford Global Technologies, LLC (Dearborn, Michigan) |
| INVENTOR(S) | Eric Matthew Kurtz (Dearborn, Michigan) |
| ABSTRACT | Methods and systems are provided for a ducted fuel injector. In one example, a method may include adjusting a temperature of combustion chamber gases in a combustion chamber and/or adjusting a fuel rail pressure in response to an amount of light sensed by a photodiode of the duct. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804965 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 23/04 (20130101) Original (OR) Class Controlling Combustion Engines F02D 41/005 (20130101) F02D 41/1439 (20130101) F02D 41/1466 (20130101) F02D 41/3836 (20130101) F02D 2041/389 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 61/16 (20130101) F02M 61/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544749 | Fedewa |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
| ASSIGNEE(S) | DELPHI TECHNOLOGIES IP LIMITED (, Barbados) |
| INVENTOR(S) | Andrew Fedewa (Clarkston, Michigan) |
| ABSTRACT | A method for controlling an internal combustion engine having a plurality of cylinders including a first cylinder and one or more remaining cylinders includes selecting a desired auto-ignition dwell for a first combustion cycle for the first cylinder of the plurality of cylinders. A first fuel mass is provided to the first cylinder which is combusted during the first combustion cycle. An actual auto-ignition dwell for the first combustion cycle which results from the first fuel mass is determined and a dwell error is calculated. The dwell error is used to determine a second fuel mass which provided to the first cylinder and which is combusted during the second combustion cycle. |
| FILED | Thursday, October 11, 2018 |
| APPL NO | 16/157206 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 1/14 (20130101) Controlling Combustion Engines F02D 41/008 (20130101) F02D 41/38 (20130101) F02D 41/3017 (20130101) Original (OR) Class F02D 2041/389 (20130101) F02D 2041/3052 (20130101) F02D 2200/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544912 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | ABL IP Holding, LLC (Conyers, Georgia) |
| ASSIGNEE(S) | ABL IP Holding, LLC (Conyers, Georgia) |
| INVENTOR(S) | Min-Hao Michael Lu (Castro Valley, California); Jonathon Wickus (Winona, Minnesota) |
| ABSTRACT | A loadable cassette holds a planar light source, such as a flat OLED panel, along with a companion driver board in a manner that allows both the light source and driver board to be operatively and replaceably connected to a luminaire or lighting system. The cassette maintains an air gap between the light source and driver board so as to prevent heat produced by the driver board from damaging the light source. |
| FILED | Monday, January 23, 2017 |
| APPL NO | 15/412708 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Non-portable Lighting Devices; Systems Thereof; Vehicle Lighting Devices Specially Adapted for Vehicle Exteriors F21S 2/00 (20130101) Original (OR) Class Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 15/01 (20130101) F21V 19/001 (20130101) F21V 21/34 (20130101) F21V 23/006 (20130101) F21V 23/06 (20130101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2115/15 (20160801) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 20/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544965 | Vetrovec |
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| FUNDED BY |
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| APPLICANT(S) | Jan Vetrovec (Larkspur, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jan Vetrovec (Larkspur, Colorado) |
| ABSTRACT | The invention is for an apparatus and method for a refrigerator and a heat pump based on the magnetocaloric effect (MCE) offering a simpler, lighter, robust, more compact, environmentally compatible, and energy efficient alternative to traditional vapor-compression devices. The subject magnetocaloric apparatus alternately exposes a magnetocaloric material to strong and weak magnetic field while switching heat to and from the material. Action of the heat switches is coordinated with the magnetic field strength to move heat up the thermal gradient. The invention may be practiced with multiple magnetocaloric stages to attain large differences in temperature. Key applications include thermal management of electronics, as well as industrial and home refrigeration, heating, and air conditioning. The invention offers a simpler, lighter, compact, and robust apparatus compared to magnetocaloric devices of prior art. Furthermore, the invention may be run in reverse as a thermodynamic engine, receiving low-level heat and producing mechanical energy. |
| FILED | Tuesday, August 15, 2017 |
| APPL NO | 15/731852 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) Original (OR) Class F25B 2321/0021 (20130101) F25B 2321/0022 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/02 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 2013/008 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545518 | Shetty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ademco Inc. (Golden Valley, Minnesota) |
| ASSIGNEE(S) | Ademco Inc. (Golden Valley, Minnesota) |
| INVENTOR(S) | Pradeep Shetty (Bangalore, India); Wendy Foslien Graber (Woodbury, Minnesota); Purnaprajna R. Mangsuli (Bangalore, India); Soumitri N. Kolavennu (Blaine, Minnesota); Keith L. Curtner (St. Paul, Minnesota) |
| ABSTRACT | A controller for controlling energy consumption in a home includes a constraints engine to define variables for multiple appliances in the home corresponding to various home modes and persona of an occupant of the home. A modeling engine models multiple paths of energy utilization of the multiple appliances to place the home into a desired state from a current context. An optimal scheduler receives the multiple paths of energy utilization and generates a schedule as a function of the multiple paths and a selected persona to place the home in a desired state. |
| FILED | Tuesday, December 12, 2017 |
| APPL NO | 15/839556 |
| ART UNIT | 2118 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 23/1923 (20130101) Original (OR) Class G05D 23/1924 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/382 (20130101) H02J 13/0079 (20130101) H02J 2003/003 (20130101) H02J 2003/007 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/2823 (20130101) H04L 12/2827 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 70/325 (20130101) Y02B 70/3275 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 40/72 (20130101) Y02E 60/76 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/54 (20130101) Y04S 10/123 (20130101) Y04S 20/228 (20130101) Y04S 20/244 (20130101) Y04S 40/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545746 | Peterson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Elena S. Peterson (Richland, Washington); Christopher S. Oehmen (Richland, Washington); Aaron R. Phillips (Richland, Washington); Darren S. Curtis (West Richland, Washington) |
| ABSTRACT | In a dynamic computing environment, it is a nontrivial task to verify code running in the environment because most approaches to software similarity require extensive and time-consuming analysis of a binary, or the approaches fail to recognize executables that are similar but nonidentical. A biosequence-based method for quantifying similarity of executable binaries is used to identify allowed codes in a real-world multi-user environment. |
| FILED | Monday, December 24, 2018 |
| APPL NO | 16/231711 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/53 (20130101) Original (OR) Class G06F 8/75 (20130101) G06F 8/427 (20130101) G06F 8/751 (20130101) G06F 21/64 (20130101) G06F 21/563 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545839 | Andrade Costa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Carlos Henrique Andrade Costa (White Plains, New York); Yoonho Park (Chappaqua, New York); Chen-Yong Cher (Port Chester, New York); Bryan Rosenburg (Cortlandt Manor, New York); Kyung Ryu (New City, New York) |
| ABSTRACT | A method is disclosed, as well as an associated apparatus and computer program product, for checkpointing using a plurality of communicatively coupled compute nodes. The method comprises acquiring health information for a first node of the plurality of compute nodes, and determining a first failure probability for the first node using the health information. The first failure probability corresponds to a predetermined time interval. The method further comprises selecting a second node of the plurality of compute nodes as a partner node for the first node. The second node has a second failure probability for the time interval. A composite failure probability of the first node and the second node is less than the first failure probability. The method further comprises copying checkpoint information from the first node to the partner node. |
| FILED | Friday, December 22, 2017 |
| APPL NO | 15/853343 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1471 (20130101) Original (OR) Class G06F 2201/82 (20130101) G06F 2201/805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545977 | Stolte et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California) |
| INVENTOR(S) | Chris Stolte (Seattle, Washington); Diane L. Tang (Palo Alto, California); Patrick Hanrahan (Portola Valley, California) |
| ABSTRACT | An exemplary method of displaying a data visualization includes retrieving a dataset that includes a plurality of fields and displaying a graphical user interface with a plurality of shelves. The method further includes receiving user actions to: (i) associate a first field with a first shelf, and (ii) associate a second field with a second shelf; displaying, in accordance with the received user actions, a data visualization, where each data mark has a first size defined according to a default position of a displayed slidable affordance; and receiving an additional user action that moves the slidable affordance from the default position to a user-defined position. In response to receiving the additional user action, the method further includes updating the data visualization, where each data mark included in the updated data visualization has a second size, different from the first size, defined according to the user-defined position of the slidable affordance. |
| FILED | Thursday, September 20, 2018 |
| APPL NO | 16/137071 |
| ART UNIT | 2166 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/04842 (20130101) G06F 3/04847 (20130101) G06F 16/26 (20190101) G06F 16/212 (20190101) G06F 16/221 (20190101) G06F 16/248 (20190101) Original (OR) Class G06F 16/252 (20190101) G06F 16/282 (20190101) G06F 16/283 (20190101) G06F 16/2282 (20190101) G06F 17/245 (20130101) G06F 17/246 (20130101) G06F 2216/03 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 707/954 (20130101) Y10S 707/956 (20130101) Y10S 707/959 (20130101) Y10S 707/99942 (20130101) Y10S 707/99943 (20130101) Y10S 707/99944 (20130101) Y10S 707/99945 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546051 | Roberts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Randy S. Roberts (Livermore, California); John Goforth (Carlsbad, California) |
| ABSTRACT | An annotation system for providing annotations for original images is provided. In some embodiments, the annotation system accesses an annotation associated with an object of a 3D model. The annotation system also accesses and displays an original image. The annotation system renders a model image of the 3D model based on the view from which the original image was collected. When the model image contains the annotated object, the annotation system provides an indication that an annotation is associated with the object of the original image. The annotation system can provide indications of the annotation for other original images that include the annotated object irrespective of the view from which the other original images are collected. |
| FILED | Tuesday, May 08, 2018 |
| APPL NO | 15/974538 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 17/241 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 3/0068 (20130101) G06T 17/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546841 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | John A. Rogers (Champaign, Illinois); Ralph Nuzzo (Champaign, Illinois); Hoon-sik Kim (Champaign, Illinois); Eric Brueckner (Champaign, Illinois); Sang Il Park (Savoy, Illinois); Rak Hwan Kim (Champaign, Illinois) |
| ABSTRACT | Described herein are printable structures and methods for making, assembling and arranging electronic devices. A number of the methods described herein are useful for assembling electronic devices where one or more device components are embedded in a polymer which is patterned during the embedding process with trenches for electrical interconnects between device components. Some methods described herein are useful for assembling electronic devices by printing methods, such as by dry transfer contact printing methods. Also described herein are GaN light emitting diodes and methods for making and arranging GaN light emitting diodes, for example for display or lighting systems. |
| FILED | Monday, March 27, 2017 |
| APPL NO | 15/470780 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/6835 (20130101) H01L 24/83 (20130101) H01L 24/95 (20130101) H01L 25/50 (20130101) H01L 25/0753 (20130101) Original (OR) Class H01L 33/32 (20130101) H01L 33/54 (20130101) H01L 33/62 (20130101) H01L 33/0079 (20130101) H01L 33/486 (20130101) H01L 33/507 (20130101) H01L 2221/6835 (20130101) H01L 2221/68322 (20130101) H01L 2221/68354 (20130101) H01L 2221/68363 (20130101) H01L 2221/68386 (20130101) H01L 2224/8312 (20130101) H01L 2224/83868 (20130101) H01L 2224/83871 (20130101) H01L 2224/83874 (20130101) H01L 2224/95085 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/06 (20130101) H01L 2924/14 (20130101) H01L 2924/14 (20130101) H01L 2924/181 (20130101) H01L 2924/181 (20130101) H01L 2924/01322 (20130101) H01L 2924/01322 (20130101) H01L 2924/1461 (20130101) H01L 2924/2064 (20130101) H01L 2924/05432 (20130101) H01L 2924/12033 (20130101) H01L 2924/12033 (20130101) H01L 2924/12036 (20130101) H01L 2924/12041 (20130101) H01L 2924/12041 (20130101) H01L 2924/12042 (20130101) H01L 2924/12043 (20130101) H01L 2924/13063 (20130101) H01L 2924/13064 (20130101) H01L 2924/13064 (20130101) H01L 2924/13091 (20130101) H01L 2924/13091 (20130101) H01L 2924/15787 (20130101) H01L 2924/15787 (20130101) H01L 2924/15788 (20130101) H01L 2924/15788 (20130101) H01L 2924/20641 (20130101) H01L 2933/005 (20130101) H01L 2933/0041 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 438/977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546976 | Matias et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | iBeam Materials, Inc. (Santa Fe, New Mexico) |
| ASSIGNEE(S) | iBeam Materials, Inc. (Santa Fe, New Mexico) |
| INVENTOR(S) | Vladimir Matias (Santa Fe, New Mexico); Christopher Yung (Louisville, Colorado) |
| ABSTRACT | A multilayer structure including a hexagonal epitaxial layer, such as GaN or other group III-nitride (III-N) semiconductors, a <111> oriented textured layer, and a non-single crystal substrate, and methods for making the same. The textured layer has a crystalline alignment preferably formed by the ion-beam assisted deposition (IBAD) texturing process and can be biaxially aligned. The in-plane crystalline texture of the textured layer is sufficiently low to allow growth of high quality hexagonal material, but can still be significantly greater than the required in-plane crystalline texture of the hexagonal material. The IBAD process enables low-cost, large-area, flexible metal foil substrates to be used as potential alternatives to single-crystal sapphire and silicon for manufacture of electronic devices, enabling scaled-up roll-to-roll, sheet-to-sheet, or similar fabrication processes to be used. The user is able to choose a substrate for its mechanical and thermal properties, such as how well its coefficient of thermal expansion matches that of the hexagonal epitaxial layer, while choosing a textured layer that more closely lattice matches that layer. Electronic devices such as LEDs can be manufactured from such structures. Because the substrate can act as both a reflector and a heat sink, transfer to other substrates, and use of external reflectors and heat sinks, is not required, greatly reducing costs. Large area devices such as light emitting strips or sheets may be fabricated using this technology. |
| FILED | Tuesday, March 26, 2019 |
| APPL NO | 16/365521 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/0262 (20130101) H01L 21/02425 (20130101) H01L 21/02458 (20130101) H01L 21/02488 (20130101) H01L 21/02505 (20130101) H01L 21/02516 (20130101) H01L 31/00 (20130101) H01L 33/007 (20130101) H01L 33/12 (20130101) H01L 33/18 (20130101) H01L 33/32 (20130101) Original (OR) Class H01L 33/60 (20130101) H01L 33/644 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546990 | Schwede et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Spark Thermionics, Inc. (Berkeley, California) |
| ASSIGNEE(S) | Spark Thermonics, Inc. (Berkeley, California) |
| INVENTOR(S) | Jared William Schwede (Berkeley, California); Lucas Heinrich Hess (Berkeley, California) |
| ABSTRACT | A thermionic energy converter, preferably including an anode and a cathode. An anode of a thermionic energy converter, preferably including an n-type semiconductor, one or more supplemental layers, and an electrical contact. A method for work function reduction and/or thermionic energy conversion, preferably including inputting thermal energy to a thermionic energy converter, illuminating an anode of the thermionic energy converter, thereby preferably reducing a work function of the anode, and extracting electrical power from the system. |
| FILED | Wednesday, December 12, 2018 |
| APPL NO | 16/218032 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 45/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/14 (20130101) H01L 35/18 (20130101) H01L 35/22 (20130101) H01L 35/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547046 | Merrill et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Matthew Merrill (Dublin, California); Michael Stadermann (Pleasanton, California) |
| ABSTRACT | According to one embodiment, a method includes forming a nickel oxide/hydroxide active film onto a substrate from a solution including a nickelous salt and an electrolyte, where the nickel oxide/hydroxide active film has a physical characteristic of maintaining greater than about 80% charge over greater than 500 charge/discharge cycles, and wherein the nickel oxide/hydroxide active film has a physical characteristic of storing electrons at greater than about 0.5 electron per nickel atom. |
| FILED | Friday, February 12, 2016 |
| APPL NO | 15/043226 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0452 (20130101) Original (OR) Class H01M 4/525 (20130101) H01M 10/30 (20130101) H01M 2220/30 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/755 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547088 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Ji-Guang Zhang (Richland, Washington); Brian D. G. Adams (Richland, Washington); Wu Xu (Richland, Washington); Jianming Zheng (Richland, Washington) |
| ABSTRACT | Embodiments of a method for cycling a rechargeable alkali metal battery with high Coulombic efficiency (CE) are disclosed. A slow charge/rapid discharge protocol is used in conjunction with a concentrated electrolyte to achieve high CE in rechargeable lithium and sodium batteries, include anode-free batteries. In some examples, the CE is ≥99.8%. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/142322 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/136 (20130101) H01M 4/381 (20130101) H01M 4/382 (20130101) H01M 4/661 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/446 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0028 (20130101) H01M 2300/0037 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0042 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547180 | Crawford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Alasdair James Crawford (Richland, Washington); Vilayanur Venkataraman Viswanathan (Richland, Washington); Patrick Joseph Balducci (West Linn, Oregon); Trevor D. Hardy (Richland, Washington); Di Wu (Richland, Washington); Michael C. W. Kintner-Meyer (Richland, Washington) |
| ABSTRACT | Systems, methods, and computer media for battery system management and non-linear estimation of battery state of charge are provided herein. Battery data is received for a time period over which a battery system has operated. The battery data represents the actual performance of the battery system over the time period. Sub-periods of charging or discharging can be identified in the time period. For the sub-periods of time, a curve can be fit to the battery data. Using the curves for the battery data for the sub-periods of time, an expected performance of the battery system, over a range of states-of-charge, can be determined. Operating instructions for the battery system can be provided based on the expected performance. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/395389 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/05 (20130101) G05B 2219/1137 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0021 (20130101) Original (OR) Class H02J 2007/0098 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547805 | Sanchez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Marcos O. Sanchez (Albuquerque, New Mexico); Liam D. Claus (Albuquerque, New Mexico); Gideon Robertson (Albuquerque, New Mexico); Sean Pearson (Albuquerque, New Mexico); Andrew Montoya (Albuquerque, New Mexico) |
| ABSTRACT | A pattern generator circuit includes a high-speed shift register and a non-overlap generator. The shift register is programmable to produce a pulse train of pulses having a defined pulse duration and a defined pulse-to-pulse interval. The non-overlap generator deserializes the incoming pulse train, and it produces a time-separated reset pulse based on the pulse train. The shift register is configured to permit the pulse durations and pulse-to-pulse interval to be selected arbitrarily over specified ranges in increments of a basic time unit that depends on the oscillator period. |
| FILED | Wednesday, July 11, 2018 |
| APPL NO | 16/032227 |
| ART UNIT | 2696 — Selective Visual Display Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14634 (20130101) H01L 27/14636 (20130101) H01L 27/14643 (20130101) Pictorial Communication, e.g Television H04N 5/374 (20130101) Original (OR) Class H04N 5/3765 (20130101) H04N 5/37452 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10543280 | Maynard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Heather D. Maynard (Los Angeles, California); Rock J. Mancini (Los Angeles, California); Juneyoung Lee (Los Angeles, California); En-Wei Lin (Los Angeles, California) |
| ABSTRACT | Compositions and methods for stabilizing biomolecules are disclosed. Specifically, the compositions include novel homopolymers or copolymers containing trehalose side chains conjugated to biomolecules. When such homopolymers or copolymers are placed in close proximity to biomolecules, such as proteins, the homopolymers or copolymers protect and/or stabilize the biomolecule. The compositions and methods may be suitable for use in various industries such as healthcare (pharmaceuticals), molecular biology, biofuels, paper, personal care, detergent, photographic, rubber, brewing, dairy and food processing industries. |
| FILED | Monday, January 29, 2018 |
| APPL NO | 15/882120 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 38/47 (20130101) A61K 47/58 (20170801) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 3/04 (20130101) C07H 17/04 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 10/00 (20130101) C08F 110/00 (20130101) C08F 210/00 (20130101) Enzymes C12Y 302/01017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543285 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Researh Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Jian Yang (State College, Pennsylvania); Cheng Dong (State College, Pennsylvania); Zhiwei Xie (State College, Pennsylvania) |
| ABSTRACT | In one aspect, methods of targeted nanoparticle and cell delivery are described herein. In some embodiments, methods described herein comprise coupling nanoparticles and cells to a carrier cell to form a nanoparticle-cell conjugate or cell-cell conjugate, disposing the nanoparticle-cell or cell-cell conjugate in a biological environment, and delivering the nanoparticles and cells to target cells or tissues located within the biological environment. The nanoparticles comprise a biodegradable photoluminescent polymer, and the nanoparticle-cell conjugate is formed using one or more click chemistry reaction products. |
| FILED | Thursday, April 13, 2017 |
| APPL NO | 16/089824 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 47/65 (20170801) A61K 47/593 (20170801) A61K 47/6901 (20170801) Original (OR) Class A61K 47/6937 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543476 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Yinyong Li (Sunderland, Massachusetts); Kenneth Raymond Carter (Hadley, Massachusetts); Kara Martin (Amherst, Massachusetts) |
| ABSTRACT | Disclosed herein is a porous material comprising a biopolymer functionalized with a carbon dioxide capturing moiety; where the biopolymer is in the form of a foam or an aerogel having a bulk density of 500 grams per cubic meter to 2500 grams per cubic meter. Disclosed herein too is a method comprising functionalizing a biopolymer with a carbon dioxide capturing moiety; dissolving the biopolymer in an aqueous solution to form a first solution; reducing the temperature of the first solution to below the freezing point of the aqueous solution; displacing the aqueous solution with a first solvent that has a lower surface tension than a surface tension of the aqueous solution; and drying the first solvent to produce a porous biopolymer having a bulk density of 500 grams per cubic meter to 2500 grams per cubic meter. |
| FILED | Friday, August 04, 2017 |
| APPL NO | 15/669172 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Separation B01D 53/62 (20130101) B01D 2252/20494 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/24 (20130101) Original (OR) Class B01J 20/3064 (20130101) B01J 20/3085 (20130101) B01J 20/28011 (20130101) B01J 20/28045 (20130101) B01J 20/28047 (20130101) Polysaccharides; Derivatives Thereof C08B 15/06 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/28 (20130101) C08J 2201/05 (20130101) C08J 2205/026 (20130101) C08J 2301/08 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/041 (20170501) C08K 2201/011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543481 | Groves et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | TRUSTEES OF PRINCETON UNIVESITY (Princeton, New Jersey) |
| INVENTOR(S) | John T. Groves (Princeton, New Jersey); Xiongyi Huang (Plainsboro, New Jersey) |
| ABSTRACT | Methods of preparing fluorinated compounds by carboxylative fluorination using fluoride are contained herein. Fluorinated compounds are provided. Methods of using fluorinated compounds are contained herein. |
| FILED | Tuesday, February 09, 2016 |
| APPL NO | 15/019673 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0423 (20130101) A61K 51/0446 (20130101) A61K 51/0455 (20130101) A61K 51/0493 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/183 (20130101) Original (OR) Class B01J 2231/40 (20130101) B01J 2531/72 (20130101) Acyclic or Carbocyclic Compounds C07C 41/22 (20130101) C07C 49/80 (20130101) Heterocyclic Compounds C07D 209/48 (20130101) C07D 213/643 (20130101) C07D 319/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10543485 | Ismagilov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Rustem F. Ismagilov (Chicago, Illinois); Wenbin Du (Chicago, Illinois); Liang Li (Chicago, Illinois); Feng Shen (Chicago, Illinois); Kevin Paul Flood Nichols (Chicago, Illinois); Delai Chen (Cambridge, Massachusetts); Jason Eugene Kreutz (Chicago, Illinois) |
| ABSTRACT | A device is described having a first surface having a plurality of first areas and a second surface having a plurality of second areas. The first surface and the second surface are opposed to one another and can move relative to each other from at least a first position where none of the plurality of first areas, having a first substance, are exposed to plurality of second areas, having a second substance, to a second position. When in the second position, the plurality of first and second areas, and therefore the first and second substances, are exposed to one another. The device may further include a series of ducts in communication with a plurality of first second areas to allow for a substance to be disposed in, or upon, the plurality of second areas when in the first position. |
| FILED | Wednesday, May 25, 2016 |
| APPL NO | 15/164788 |
| ART UNIT | 1799 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/0094 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5025 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 3/502738 (20130101) B01L 3/502761 (20130101) B01L 7/52 (20130101) B01L 2200/025 (20130101) B01L 2200/027 (20130101) B01L 2300/12 (20130101) B01L 2300/168 (20130101) B01L 2300/0609 (20130101) B01L 2300/0809 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0887 (20130101) B01L 2300/0893 (20130101) B01L 2400/065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) C12Q 1/703 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 33/54386 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544191 | Fasan |
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| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Rudi Fasan (Rochester, New York) |
| ABSTRACT | Methods and compositions are provided for generating macrocyclic peptides from genetically encoded, ribosomally produced polypeptide precursors. Also provided are nucleic acid molecules, polypeptides, and methods for generating combinatorial libraries of macrocyclic peptides. These methods can be used to produce vast libraries of conformationally constrained peptide ligands as well as facilitate the functional screening of these libraries to identify compound(s) with desired activity properties. |
| FILED | Tuesday, December 23, 2014 |
| APPL NO | 15/107387 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 7/54 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544312 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Shaoyi Jiang (Redmond, Washington); Yuting Li (Seattle, Washington); Hong Xue (Pleasanton, California); Shengfu Chen (Hangzhou, China PRC) |
| ABSTRACT | Marine coatings including cationic polymers hydrolyzable to nonfouling zwitterionic polymers, coated marine surfaces, and methods for making and using the marine coatings. |
| FILED | Thursday, December 29, 2016 |
| APPL NO | 15/394538 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/785 (20130101) Ships or Other Waterborne Vessels; Equipment for Shipping B63B 59/04 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/16 (20130101) C09D 5/165 (20130101) C09D 5/1606 (20130101) C09D 5/1637 (20130101) Original (OR) Class C09D 5/1656 (20130101) C09D 5/1662 (20130101) C09D 5/1668 (20130101) C09D 5/1675 (20130101) C09D 133/26 (20130101) C09D 151/085 (20130101) C09D 153/00 (20130101) C09D 183/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/3154 (20150401) Y10T 428/31511 (20150401) Y10T 428/31551 (20150401) Y10T 428/31663 (20150401) Y10T 428/31725 (20150401) Y10T 428/31786 (20150401) Y10T 428/31844 (20150401) Y10T 428/31938 (20150401) Y10T 428/31942 (20150401) Y10T 442/10 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544974 | Goldfarbmuren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rebound Technologies, Inc. (Commerce City, Colorado) |
| ASSIGNEE(S) | Rebound Technologies, Inc. (Commerce City, Colorado) |
| INVENTOR(S) | Russell Goldfarbmuren (Denver, Colorado); Luke Erickson (Denver, Colorado); Josh Nelson (Bennett, Colorado); John Darrah (Winter Park, Florida); Mauricio Sanchez (Denver, Colorado); Chance Lord (Denver, Colorado) |
| ABSTRACT | Methods, systems, and device for solidification and/or solid production, such as ice production, are provided in accordance with various embodiments. For example, some embodiments include a method of solid production that may include contacting a first fluid with a second fluid to facilitate solidifying the second fluid; the first fluid and the second fluid may be immiscible with respect to each other. The method may include solidifying the second fluid. Some embodiments include a solid production system that may include a first fluid and a second fluid; the first fluid and the second fluid may be immiscible with respect to each other. The system may include one or more surfaces configured to contact the first fluid and the second fluid with each other and to form one or more solids from the second fluid. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/119661 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Producing, Working or Handling Ice F25C 1/12 (20130101) Original (OR) Class F25C 2300/00 (20130101) Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 3/005 (20130101) F25D 17/02 (20130101) F25D 2303/084 (20130101) F25D 2303/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545058 | Bao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Zhenan Bao (Stanford, California); Stefan Christian Bernhardt Mannsfeld (Cameron Park, California); Jason Locklin (Bogart, Georgia); Chee-Keong Tee (Stanford, California) |
| ABSTRACT | Sensors, sensing arrangements and devices, and related methods are provided. In accordance with an example embodiment, an impedance-based sensor includes a flexible dielectric material and generates an output based on pressure applied to the dielectric material and a resulting compression thereof. In certain embodiments, the dielectric material includes a plurality of regions separated by gaps and configured to elastically deform and recover in response to applied pressure. |
| FILED | Monday, March 07, 2016 |
| APPL NO | 15/062841 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/146 (20130101) Original (OR) Class G01L 1/148 (20130101) Electric Digital Data Processing G06F 3/044 (20130101) G06F 3/0412 (20130101) G06F 3/0414 (20130101) G06F 2203/04102 (20130101) G06F 2203/04103 (20130101) G06F 2203/04107 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/84 (20130101) H01L 51/0055 (20130101) H01L 51/0541 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49002 (20150115) Y10T 156/10 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545123 | Lyman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Seth N Lyman (Vernal, Utah) |
| ASSIGNEE(S) | Utah State University (, None) |
| INVENTOR(S) | Seth N Lyman (Vernal, Utah) |
| ABSTRACT | Embodiments disclosed herein are directed to gaseous mercury detection systems, calibration systems, and related methods. The gaseous mercury detection systems are configured to detect gas-phase mercury-compounds present in ambient air. For example, the gaseous mercury detection systems collect gas-phase mercury-compounds from ambient air and release the gas-phase mercury-compounds at concentrations capable of being measured by a gas-chromatography mass spectrometer without heating the gas-phase mercury-compounds above a decomposition temperature of at least one gaseous mercury compound that may present in the mercury-containing gas. The calibration systems are configured to determine an accuracy of or calibrate a gaseous mercury detection system. The disclosed calibration systems may be integrated with or distinct from the gaseous mercury detection systems disclosed herein. |
| FILED | Tuesday, June 05, 2018 |
| APPL NO | 16/000541 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/08 (20130101) G01N 30/7206 (20130101) Original (OR) Class G01N 33/0045 (20130101) G01N 2030/025 (20130101) G01N 2030/085 (20130101) G01N 2030/121 (20130101) G01N 2030/143 (20130101) G01N 2030/626 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0422 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545219 | Przybyla et al. |
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| FUNDED BY |
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| APPLICANT(S) | Chirp Microsystems (Berkeley, California) |
| ASSIGNEE(S) | CHIRP MICROSYSTEMS (Berkeley, California) |
| INVENTOR(S) | Richard J. Przybyla (Emeryville, California); David A. Horsley (Berkeley, California); Mitchell H. Kline (Alameda, California) |
| ABSTRACT | A tracking method is disclosed. The method may include displaying visual content on a screen. A base station may be stationary with respect to the screen while the visual content is being displayed. In contrast, one or more objects may move with respect to the screen while the visual content is being displayed. The one or more objects may be tracked so that the movement thereof may be used to alter the visual content. Such tracking may involve the base station and the one or more objects sending and/or receiving one or more ultrasonic pulses. Time-difference-of-arrival and/or time-of-flight of the one or more ultrasonic pulses may then be used to estimate a relative location and/or a relative orientation of the one or more objects with respect to the base station in three dimensional space. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/360673 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/26 (20130101) Original (OR) Class G01S 5/0263 (20130101) Wireless Communication Networks H04W 56/0015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545873 | Peng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| INVENTOR(S) | Lu Peng (Baton Rouge, Louisiana); Ashok Srivastava (Baton Rouge, Louisiana); Shaoming Chen (Baton Rouge, Louisiana) |
| ABSTRACT | Embodiments of the present invention include methods for increasing off-chip bandwidth. The method includes designing a circuit of switchable pins, replacing a portion of allocated pins of a processor with switchable pins, connecting the processor to a memory interface configured to switch the switchable pins between a power mode and a signal mode, providing a metric configured to identify which of the power mode and the signal mode is most beneficial during 1 millisecond intervals, and switching the switchable pins to signal mode during intervals where the signal mode provides more benefit than the power mode. |
| FILED | Friday, August 24, 2018 |
| APPL NO | 16/111827 |
| ART UNIT | 2185 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0862 (20130101) Original (OR) Class G06F 13/409 (20130101) G06F 13/1668 (20130101) G06F 13/4072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546395 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Delaware (Newark, Delaware) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Jingyi Yu (Newark, Delaware); Jinwei Ye (Elkton, Maryland); Yu Ji (Elkton, Maryland) |
| ABSTRACT | Light representing a scene is directed through a lens module coupled to an imaging sensor. The lens module includes: first and second cylindrical lenses positioned along an optical axis of the imaging sensor, and first and second slit-shaped apertures disposed on the respective first and second cylindrical lenses. A cylindrical axis of the second cylindrical lens is arranged at an angle away from parallel with respect to a cylindrical axis of the first cylindrical lens. The light directed through the lens module is captured by the imaging sensor to form at least one multi-perspective image. The at least one multi-perspective image is processed to determine a reconstruction characteristic of the scene. |
| FILED | Friday, October 03, 2014 |
| APPL NO | 15/026768 |
| ART UNIT | 2489 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/001 (20130101) G06T 11/003 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/2253 (20130101) H04N 5/2254 (20130101) H04N 13/204 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546417 | Black et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Michael J. Black (Providence, Rhode Island); Alexandru O. Balan (Pawtucket, Rhode Island); Alexander W. Weiss (Shirley, Massachusetts); Leonid Sigal (Pittsburgh, Pennsylvania); Matthew M. Loper (Providence, Rhode Island); Timothy S. St. Clair (Cambridge, Massachusetts) |
| ABSTRACT | A system and method of estimating the body shape of an individual from input data such as images or range maps. The body may appear in one or more poses captured at different times and a consistent body shape is computed for all poses. The body may appearin minimal tight-fitting clothing or in normal clothing wherein the described method produces an estimate of the body shape under the clothing. Clothed or bare regions of the body are detected via image classification and the fitting method is adapted to treat each region differently. Body shapes are represented parametrically and are matched to other bodies based on shape similarity and other features. Standard measurements are extracted using parametric or non-parametric functions of body shape. The system components support many applications in body scanning, advertising, social networking, collaborative filtering and Internet clothing shopping. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 16/453135 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00369 (20130101) G06K 9/6221 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0601 (20130101) Image Data Processing or Generation, in General G06T 7/75 (20170101) G06T 7/77 (20170101) G06T 17/00 (20130101) Original (OR) Class G06T 2207/10028 (20130101) G06T 2207/30196 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546433 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Ming C. Lin (Chapel Hill, North Carolina); Shan Yang (Sunnyvale, California) |
| ABSTRACT | Methods, systems, and computer readable media for modeling garments using single view images are disclosed. According to one method, the method includes receiving an image depicting a person wearing at least one garment. The method also includes constructing a body model based on the person in the image and a template from a body model database. The method further includes constructing at least one garment model based on the at least one garment in the image and at least one template from a garment model database. The method also includes constructing a combined model based on the body model and the at least one garment model. The method further includes adjusting the combined model by modifying body pose parameters and determining garment material properties and sizing parameters. |
| FILED | Friday, August 03, 2018 |
| APPL NO | 16/054599 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00362 (20130101) Image Data Processing or Generation, in General G06T 7/62 (20170101) G06T 7/75 (20170101) G06T 17/205 (20130101) G06T 19/20 (20130101) Original (OR) Class G06T 2210/16 (20130101) G06T 2219/2004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546841 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | John A. Rogers (Champaign, Illinois); Ralph Nuzzo (Champaign, Illinois); Hoon-sik Kim (Champaign, Illinois); Eric Brueckner (Champaign, Illinois); Sang Il Park (Savoy, Illinois); Rak Hwan Kim (Champaign, Illinois) |
| ABSTRACT | Described herein are printable structures and methods for making, assembling and arranging electronic devices. A number of the methods described herein are useful for assembling electronic devices where one or more device components are embedded in a polymer which is patterned during the embedding process with trenches for electrical interconnects between device components. Some methods described herein are useful for assembling electronic devices by printing methods, such as by dry transfer contact printing methods. Also described herein are GaN light emitting diodes and methods for making and arranging GaN light emitting diodes, for example for display or lighting systems. |
| FILED | Monday, March 27, 2017 |
| APPL NO | 15/470780 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/6835 (20130101) H01L 24/83 (20130101) H01L 24/95 (20130101) H01L 25/50 (20130101) H01L 25/0753 (20130101) Original (OR) Class H01L 33/32 (20130101) H01L 33/54 (20130101) H01L 33/62 (20130101) H01L 33/0079 (20130101) H01L 33/486 (20130101) H01L 33/507 (20130101) H01L 2221/6835 (20130101) H01L 2221/68322 (20130101) H01L 2221/68354 (20130101) H01L 2221/68363 (20130101) H01L 2221/68386 (20130101) H01L 2224/8312 (20130101) H01L 2224/83868 (20130101) H01L 2224/83871 (20130101) H01L 2224/83874 (20130101) H01L 2224/95085 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/06 (20130101) H01L 2924/14 (20130101) H01L 2924/14 (20130101) H01L 2924/181 (20130101) H01L 2924/181 (20130101) H01L 2924/01322 (20130101) H01L 2924/01322 (20130101) H01L 2924/1461 (20130101) H01L 2924/2064 (20130101) H01L 2924/05432 (20130101) H01L 2924/12033 (20130101) H01L 2924/12033 (20130101) H01L 2924/12036 (20130101) H01L 2924/12041 (20130101) H01L 2924/12041 (20130101) H01L 2924/12042 (20130101) H01L 2924/12043 (20130101) H01L 2924/13063 (20130101) H01L 2924/13064 (20130101) H01L 2924/13064 (20130101) H01L 2924/13091 (20130101) H01L 2924/13091 (20130101) H01L 2924/15787 (20130101) H01L 2924/15787 (20130101) H01L 2924/15788 (20130101) H01L 2924/15788 (20130101) H01L 2924/20641 (20130101) H01L 2933/005 (20130101) H01L 2933/0041 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 438/977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547280 | Fok et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Mable P. Fok (Bishop, Georgia); Jia Ge (Athens, Georgia) |
| ABSTRACT | Various examples are provided for tunable radio frequency (RF) filtering. In one example, a RF multiband filter includes a Lyot filter including a tunable birefringence loop including a circulator and a polarization controller (PC) and a phase modulator (PM). The Lyot filter can generate an optical comb based at least in part upon a received optical signal and a polarization rotation angle of the polarization controller. The phase modulator (PM) can generate a modulated tap signal by modulating the optical comb by a RF input signal. |
| FILED | Friday, March 11, 2016 |
| APPL NO | 15/557454 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/274 (20130101) G02B 6/29389 (20130101) G02B 6/29395 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 2/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547489 | Pekoz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Berker Pekoz (Tampa, Florida); Zekeriyya Esat Ankarali (Carlsbad, California); Selcuk Kose (Tampa, Florida); Huseyin Arslan (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Berker Pekoz (Tampa, Florida); Zekeriyya Esat Ankarali (Carlsbad, California); Selcuk Kose (Tampa, Florida); Huseyin Arslan (Tampa, Florida) |
| ABSTRACT | System and method based upon an OFDM symbol, including a cyclic prefix (CP), that is received after being transmitted over a multiple access channel, wherein the CP is removed, and a Hann window is applied to the symbol. FFT is then applied to the Hann windowed symbol to obtain the frequency domain subcarriers. The pilot symbols are filtered accordingly to obtain Hann windowed pilots to estimate effective channel. Inter-carrier interference is calculated and removed. |
| FILED | Tuesday, January 08, 2019 |
| APPL NO | 16/242288 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0202 (20130101) H04L 27/38 (20130101) Original (OR) Class H04L 27/2605 (20130101) H04L 27/2628 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547555 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Kyunghan Lee (Cary, North Carolina); Injong Rhee (Apex, North Carolina); Nithyananthan Poosamani (Coimbatore, India) |
| ABSTRACT | The subject matter described herein includes methods, systems, and computer readable media for reducing Wi-Fi scanning using cellular network to Wi-Fi access point mapping information. In one exemplary method, a mobile communications device receives Wi-Fi and cellular signals and creates or obtains a database of mappings between Wi-Fi access points and cellular network information. The mobile communications device detects signals from base stations in the cellular network. The mobile communications device determines at least one recommended access point from the data derived from the database. The mobile communications device determines whether any Wi-Fi signals are present. In response to determining that at least one Wi-Fi signal is present, the mobile communications device attempts to connect to the at least one recommended access point. |
| FILED | Thursday, October 04, 2012 |
| APPL NO | 14/349571 |
| ART UNIT | 3687 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0896 (20130101) H04L 47/27 (20130101) Original (OR) Class H04L 47/225 (20130101) Wireless Communication Networks H04W 28/0273 (20130101) H04W 28/0289 (20130101) H04W 48/16 (20130101) H04W 48/18 (20130101) H04W 80/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10543268 | Palese et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York); St. Jude Children's Research Hospital (Memphis, Tennessee); The United States of America, As Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); St. Jude Children's Research Hospital (Memphis, Tennessee); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Peter Palese (New York, New York); Adolfo Garcia-Sastre (New York, New York); Richard J. Webby (Memphis, Tennessee); Juergen A. Richt (Ames, Iowa); Robert G. Webster (Memphis, Tennessee); Kelly M. Lager (Colo, Iowa) |
| ABSTRACT | The present invention relates, in general, to attenuated swine influenza viruses having an impaired ability to antagonize the cellular interferon (IFN) response, and the use of such attenuated viruses in vaccine and pharmaceutical formulations. In particular, the invention relates to attenuated swine influenza viruses having modifications to a swine NS1 gene that diminish or eliminate the ability of the NS1 gene product to antagonize the cellular IFN response. These viruses replicate in vivo, but demonstrate decreased replication, virulence and increased attenuation, and therefore are well suited for use in live virus vaccines, and pharmaceutical formulations. |
| FILED | Monday, September 10, 2018 |
| APPL NO | 16/126791 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/58 (20130101) A61K 2039/544 (20130101) A61K 2039/552 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16034 (20130101) C12N 2760/16061 (20130101) C12N 2760/16121 (20130101) C12N 2760/16134 (20130101) C12N 2760/16151 (20130101) C12N 2760/16171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544085 | Bischoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth M. Bischoff (Morton, Illinois); Timothy D. Leathers (Dunlap, Illinois); Neil P. Price (Edelstein, Illinois); Pennapa Manitchotpisit (Dunlap, Illinois) |
| ABSTRACT | Compounds, called liamocins from Aureobasidium pullulans, having the general structure in Formula 1 are disclosed. where R1 is either COCH3 or H; and R2 is between two to ten O-linked 3,5-dihydroxydecanoate; and R3 can be a polyol (e.g., L- or D-glycerol, L- or D-threitol, L- or D-erythritol, L- or D-arabitol, L- or D-xylitol, L- or D-lyxitol, L- or D-ribitol, L- or D-allitol, L- or D-altritol, L- or D-mannitol, L- or D-iditol, L- or D-gulitol, L- or D-glucitol (also called sorbitol), L- or D-galactitol (also called dulcitol), and L- or D-talitol), 2-amino-D-mannitol, 2N-acetylamino-D-mannitol, L-rhamnitol, or D-fucitol; except when R3 is D-mannitol, R2 is not 2 nor 3 O-linked 3,5-dihydroxydecanoate chains. These liamocins described above in addition to D-mannitol liamocin A1, D-mannitol liamocin A2, D-mannitol liamocin B1, and D-mannitol liamocin B2, alone or in combination with each other, can be used to kill certain bacteria and to treat certain bacterial infections. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 15/919395 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/36 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/191 (20130101) Acyclic or Carbocyclic Compounds C07C 69/003 (20130101) C07C 69/21 (20130101) C07C 69/33 (20130101) C07C 69/675 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/62 (20130101) C12P 19/44 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/645 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544389 | Talaat |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Adel M. Talaat (Madison, Wisconsin) |
| ABSTRACT | Described herein is a mycobacterium mutant, comprising at least one mutation in at least one gene sequence encoding global gene regulators (GGRs) selected from the group consisting of sigH, sigL, sigE, ECF-1, and mixtures thereof, wherein the GGR gene is at least partially inactivated. Described herein also is a vaccine based on the mutant and a method of differentiating between subjects that have been infected with mycobacterium and subjects that have not been infected with mycobacterium or have been vaccinated with a mycobacterium vaccine. |
| FILED | Thursday, April 20, 2017 |
| APPL NO | 15/492553 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 2039/522 (20130101) A61K 2039/552 (20130101) Peptides C07K 14/35 (20130101) C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Original (OR) Class C12N 1/36 (20130101) C12N 15/1031 (20130101) C12N 15/1136 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 2600/156 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/32 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5695 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10544406 | Donovan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); University of Maryland, College Park (College Park, Maryland); Western University of Health Sciences (Pomona, California) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); Western University of Health Sciences (Pamona, California); University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | David M. Donovan (Essex, Maryland); Jerel Waters (Randallstown, Maryland); Dayana T. Rowley (Beltsville, Maryland); Steven M. Swift (Bethesda, Maryland); Brian B. Oakley (Claremont, California) |
| ABSTRACT | Clostridium perfringens can cause food poisoning and is a major agent in necrotic enteritis. As laws banning the use of antibiotics in animal feed become more common, the need for alternatives to antibiotics becomes greater. Peptidoglycan hydrolases that target the cell wall of specific bacteria are one such alternative. Genes for four endolysins, PlyCP10, PlyCP18, PlyCP33, and PlyCP41, were found within clusters of phage associated genes, likely prophages from strains Cp10, Cp18, Cp33, and Cp41. PlyCP18 and PlyCP33 harbor L-alanine amidase catalytic domains, and PlyCP10 and PlyCP41 have glycosyl hydrolase catalytic domains as predicted by BlastP and PFAM searches. All four genes were synthesized with E. coli codon optimization, expressed in E. coli expression vectors with a 6×His tag for nickel column purification, and the recombinant proteins purified. The four endolysins were capable of lysing the 66 C. perfringens strains tested but not the other bacteria tested. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/862951 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fodder A23K 20/189 (20160501) A23K 50/75 (20160501) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 35/74 (20130101) A61K 38/47 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Original (OR) Class C12N 15/81 (20130101) Enzymes C12Y 302/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP31407 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Florida A and M University (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida A and M University (Tallahassee, Florida) |
| INVENTOR(S) | Zhongbo Ren (Tallahassee, Florida); Jiang Lu (Shanghai, China PRC); Violeta Tsolova (Tallahassee, Florida) |
| ABSTRACT | A new and distinct cultivar of the muscadine grape plant, Vitis rotundifolia Michx., which is highly productive, resistant to Pierce's disease, low fruit ripening rot, and relatively low wet scar. The new and distinct cultivar has a very large deep black-red colored berry with an extremely pleasant fruit flavor. The cultivar has moderate vine growth with high fruit yield, and very good disease resistance. The cultivar also has an extended shelf life. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 15/999995 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10543110 | Piercy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ROAM ROBOTICS INC. (San Francisco, California) |
| ASSIGNEE(S) | ROAM ROBOTICS INC. (San Francisco, California) |
| INVENTOR(S) | Brenton Piercy (San Francisco, California); Tim Swift (Albany, California); Giancarlo Nucci (San Francisco, California); Callum Lamb (San Bruno, California); Pete Lynn (Oakland, California); Saul Griffith (San Francisco, California); Leanne Luce (San Francisco, California) |
| ABSTRACT | A lower-leg exoskeleton including an inflatable actuator that is configured to be worn over a front portion of a foot of a user; a rigid foot structure coupled to the inflatable actuator that is configured to surround a portion of a foot of the user; and a rigid shin structure coupled to the inflatable actuator and configured to engage the shin of the user. When worn by a user, the lower-leg exoskeleton can receive and transmit an actuator load generated by the inflatable actuator to a load contact point defined by the rigid foot structure which is forward of the heel of a user. Inflation of the inflatable actuator can generate a moment about the ankle of a user to cause flexion of the foot of the user. |
| FILED | Monday, March 28, 2016 |
| APPL NO | 15/082824 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/60 (20130101) A61F 2/68 (20130101) Original (OR) Class A61F 2002/74 (20130101) A61F 2002/501 (20130101) A61F 2002/745 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546207 | Sundaresan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina Agricultural and Technical State University (Greensboro, North Carolina) |
| ASSIGNEE(S) | North Carolina Agricultural and Technical State University (Greensboro, North Carolina) |
| INVENTOR(S) | Mannur J. Sundaresan (Greensboro, North Carolina); Letchuman Sripragash (Greensboro, North Carolina) |
| ABSTRACT | A method of thermographic nondestructive evaluation may include heating a portion of a surface of an object from a first surface temperature to a second surface temperature that is greater than the first surface temperature, collecting a plurality of thermal images of the portion of the surface of the object, detecting the sound zone of the portion of the surface of the object, determining a characteristic time corresponding to a time after the heating of the portion of the surface of the object wherein the sound zone of the surface of the object approaches a steady state temperature, normalizing temperature data of the plurality of thermal images with respect to the characteristic time and the steady state temperature, and detecting the defect zone based on differences between normalized temperature data of pixels of the defect zone and normalized temperature data of pixels of the sound. |
| FILED | Monday, April 10, 2017 |
| APPL NO | 15/482851 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4604 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10546666 | Shin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio Aerospace Institute (Brook Park, Ohio) |
| ASSIGNEE(S) | OHIO AEROSPACE INSTITUTE (Brook Park, Ohio); U.S. GOVERNMENT AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (Washington, District of Columbia) |
| INVENTOR(S) | Euy-sik Shin (Brook Park, Ohio) |
| ABSTRACT | A thin micro-multilayer electrical insulator having a plurality of layers of polymeric materials is high performance and lightweight. The insulator provides a structured material with improved dielectric strength and partial corona discharge resistance that can be used in high voltage and high temperature applications. The durable insulator is well suited for use in insulating high voltage aircraft wiring and power transmission composites in hybrid and all electric airplanes. The insulator can have multiple layers of different polymeric materials such as fluorine-containing polymers and polyimides. |
| FILED | Thursday, April 11, 2019 |
| APPL NO | 16/381144 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/427 (20130101) H01B 7/0009 (20130101) H01B 7/0225 (20130101) Original (OR) Class H01B 7/295 (20130101) H01B 7/1805 (20130101) Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10547251 | Pan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Di Pan (Schenectady, New York); Mark Edward Dame (Niskayuna, New York); Di Zhang (Niskayuna, New York); Jiangbiao He (Schenectady, New York) |
| ABSTRACT | A method for shutting down a phase-leg of a three-level active neutral point clamped converter is provided. The method includes the following steps. A determining step determines if a switch fault has occurred, and if a switch fault has occurred then each switch of the plurality of switches are turned off. If a switch fault has not occurred and a shutdown is requested, then an operating step operates the plurality of switches to turn off a first switch and a fourth switch. A waiting step waits for a first predetermined time period. An operating step operates the plurality of switches to turn on a second switch and a third switch. A waiting step is repeated. An operating step operates the plurality of switches to turn off a fifth switch and a sixth switch. A waiting step is repeated. An operating step turns off the second switch and the third switch. |
| FILED | Thursday, November 15, 2018 |
| APPL NO | 16/192668 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/08 (20130101) H02M 7/487 (20130101) Original (OR) Class H02M 7/539 (20130101) H02M 2001/0058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548031 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use signal constellations, which have unequally spaced (i.e. ‘geometrically’ shaped) points. In many embodiments, the communication systems use specific geometric constellations that are capacity optimized at a specific SNR, over the Rayleigh fading channel. In addition, ranges within which the constellation points of a capacity optimized constellation can be perturbed and are still likely to achieve a given percentage of the optimal capacity increase compared to a constellation that maximizes dmin, are also described. Capacity measures that are used in the selection of the location of constellation points include, but are not limited to, parallel decode (PD) capacity and joint capacity. |
| FILED | Friday, July 19, 2019 |
| APPL NO | 16/517497 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 5/006 (20130101) H04L 27/3405 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class H04W 72/0453 (20130101) H04W 72/0473 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10545012 | Sowle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zak Sowle (Bellbrook, Ohio); Srikanth Vasudevan (Monroe, Connecticut); Matthew C. Birch (Madison, Alabama) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Zak Sowle (Bellbrook, Ohio); Srikanth Vasudevan (Monroe, Connecticut); Matthew C. Birch (Madison, Alabama) |
| ABSTRACT | A projectile incorporates one or more spoiler-tabbed spinning disks to effect flow around the projectile and thus impart steering forces and/or moments. The spoiler tabs may be deployed only during steering phases of travel thus minimizing the drag penalty associated with steering systems. The disks are driven by motors and informed and controlled by sensors and electronic control systems. The spoiler tabs protrude through the surface of the projectile only for certain angles of spin of the spinning disk. For spin-stabilized projectiles, the disks spin at substantially the same rate as the projectile, but the disks may function in fin-stabilized projectiles as well. Any number of such spinning flow effector disks may be incorporated in a projectile, with the manner of functional coordination differing slightly for even and odd numbers of disks. |
| FILED | Thursday, December 27, 2018 |
| APPL NO | 16/233484 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 13/00 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/00 (20130101) F42B 10/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10545026 | Schaefer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Philip Raymond Schaefer (Weaverville, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip Raymond Schaefer (Weaverville, North Carolina) |
| ABSTRACT | A method provides navigation assistance to a user by tracking the user's position. By detecting similar features, the accuracy of the position measurement of the user is improved, making use of a priori frequencies that various feature types exist in the area. The method provides techniques for planning a route using the tracking information and is able to explore previously-untraveled paths in response to a setting in the search process. The navigation information can be saved or retrieved from a database so that users may share the data obtained during navigating an unfamiliar area. |
| FILED | Monday, June 04, 2018 |
| APPL NO | 15/997552 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/343 (20130101) G01C 21/3476 (20130101) Original (OR) Class G01C 21/3484 (20130101) G01C 21/3617 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10545259 | Guzman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as Represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Felipe Guzman (Derwood, Maryland); Lee Michael Kumanchik (Brandon, Florida); Jacob M. Taylor (Washington, District of Columbia); Jon R. Pratt (Clarksburg, Maryland) |
| ABSTRACT | An optomechanical gravimeter includes: a first and second accelerometer; and a spacer member interposed between the first accelerometer and the second accelerometer such that the first accelerometer and the second accelerometer independently include: a basal member; a test mass disposed on the basal member; a flexural member interposed between the basal member and the test mass such that the test mass is moveably disposed on the basal member via flexing of the flexural member; an armature disposed on the basal member and opposing the test mass and the flexural member such that: the armature is spaced apart from the test mass; a cavity including: a first mirror disposed on the test mass; a second mirror disposed on the armature, the spacer member providing a substantially constant distance of separation between a first measurement point of the first accelerometer and a second measurement point of the second accelerometer. |
| FILED | Tuesday, June 27, 2017 |
| APPL NO | 15/634547 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/093 (20130101) G01P 21/00 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 7/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10546358 | Maher |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | David Maher (Washington, District of Columbia) |
| ABSTRACT | Mobile collection and vetting of user supplied information is described. The systems, techniques, devices, methods, and approaches described herein can be used to obtain, validate, and vet information, such as customs information, in a mobile environment. In embodiments, methods comprise receiving information input via a mobile device. The information is encapsulated by an intermediate to escort the information through a firewall to the database. In response to vetting the information to determine if it meets one or more criteria, the method involves creating a record associated with a unique identifier, information that bio-identifies a user, or an indication of a determination that results from the vetting. In this embodiment, the method includes generating an electronic receipt for communication to the mobile device, the electronic receipt including the unique identifier. |
| FILED | Tuesday, February 26, 2019 |
| APPL NO | 16/285520 |
| ART UNIT | 3629 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 16/83 (20190101) G06F 16/2228 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10547967 | Liao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Chen-Fu Liao (Minneapolis, Minnesota); Max Donath (Minneapolis, Minnesota) |
| ABSTRACT | A method includes a mobile device receiving data from a first beacon in a plurality of beacons, wherein the data indicates a plurality signals strengths of signals received by the first beacon from the other beacons in the plurality of beacons. The mobile device uses multivariable regression based on the data received from the first beacon and signal strengths of signals received by the mobile device from the other beacons in the plurality of beacons to determine distances from the mobile device to the beacons. The mobile device determines a location of the mobile device based on the determined distances. |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/897854 |
| ART UNIT | 2641 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Electric Digital Data Processing G06F 3/041 (20130101) G06F 3/04883 (20130101) Traffic Control Systems G08G 1/07 (20130101) Transmission H04B 17/318 (20150115) Wireless Communication Networks H04W 4/021 (20130101) Original (OR) Class H04W 4/80 (20180201) H04W 8/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 10545058 | Bao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Zhenan Bao (Stanford, California); Stefan Christian Bernhardt Mannsfeld (Cameron Park, California); Jason Locklin (Bogart, Georgia); Chee-Keong Tee (Stanford, California) |
| ABSTRACT | Sensors, sensing arrangements and devices, and related methods are provided. In accordance with an example embodiment, an impedance-based sensor includes a flexible dielectric material and generates an output based on pressure applied to the dielectric material and a resulting compression thereof. In certain embodiments, the dielectric material includes a plurality of regions separated by gaps and configured to elastically deform and recover in response to applied pressure. |
| FILED | Monday, March 07, 2016 |
| APPL NO | 15/062841 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/146 (20130101) Original (OR) Class G01L 1/148 (20130101) Electric Digital Data Processing G06F 3/044 (20130101) G06F 3/0412 (20130101) G06F 3/0414 (20130101) G06F 2203/04102 (20130101) G06F 2203/04103 (20130101) G06F 2203/04107 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/84 (20130101) H01L 51/0055 (20130101) H01L 51/0541 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49002 (20150115) Y10T 156/10 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 10546994 | Dial et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Oliver Dial (Yorktown Heights, New York); Jay M. Gambetta (Yorktown Heights, New York); Douglas T. McClure, III (Rye, New York); Matthias Steffen (Cortlandt Manor, New York) |
| ABSTRACT | A technique relates a superconducting microwave cavity. An array of posts has different heights in the cavity, and the array supports a localized microwave mode. The array of posts includes lower resonant frequency posts and higher resonant frequency posts. The higher resonant frequency posts are arranged around the lower resonant frequency posts. A first plate is opposite a second plate in the cavity. One end of the lower resonant frequency posts is positioned on the second plate so as to be electrically connected to the second plate. Another end of the lower resonant frequency posts in the array is open so as not to form an electrical connection to the first plate. Qubits are connected to the lower resonant frequency posts in the array of posts, such that each of the qubits is physically connected to one or two of the lower resonant frequency posts in the array of posts. |
| FILED | Tuesday, August 28, 2018 |
| APPL NO | 16/114797 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) G06N 20/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/14 (20130101) H01L 39/24 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US PP31407 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Florida A and M University (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida A and M University (Tallahassee, Florida) |
| INVENTOR(S) | Zhongbo Ren (Tallahassee, Florida); Jiang Lu (Shanghai, China PRC); Violeta Tsolova (Tallahassee, Florida) |
| ABSTRACT | A new and distinct cultivar of the muscadine grape plant, Vitis rotundifolia Michx., which is highly productive, resistant to Pierce's disease, low fruit ripening rot, and relatively low wet scar. The new and distinct cultivar has a very large deep black-red colored berry with an extremely pleasant fruit flavor. The cultivar has moderate vine growth with high fruit yield, and very good disease resistance. The cultivar also has an extended shelf life. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 15/999995 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10543570 | Argentine |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BWXT Nuclear Operations Group, Inc. (Lynchburg, Virginia) |
| ASSIGNEE(S) | BWXT Nuclear Operations Group, Inc. (Lynchburg, Virginia) |
| INVENTOR(S) | Frank A. Argentine (Copley, Ohio) |
| ABSTRACT | Properties and performance of weld material between metals in a weldment is controlled by modifying one or more of the nitrogen content and the carbon content to produce carbide (e.g. MC-type), nitride and/or complex carbide/nitride (e.g. MX-type) type precipitates. Fusion welding includes (i) adjusting shield gas composition to increase nitrogen/carbon gas and nitride/carbide species, (ii) adjusting composition of nitrogen/carbon in materials that participate in molten welding processes, (iii) direct addition of nitrides/carbides (e.g. powder form), controlled addition of nitride/carbide forming elements (e.g. Ti, Al), or addition of elements that increase/impede solubility of nitrogen/carbon or nitride/carbide promoting elements (e.g. Mn), and (iv) other processes, such as use of fluxes and additive materials. Weld materials have improved resistance to different cracking mechanisms (e.g., hot cracking mechanisms and solid state cracking mechanisms) and improved tensile related mechanical properties. |
| FILED | Tuesday, February 21, 2017 |
| APPL NO | 15/437901 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 9/167 (20130101) B23K 9/173 (20130101) B23K 35/304 (20130101) Original (OR) Class B23K 2103/18 (20180801) Alloys C22C 19/058 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, January 28, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200128.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page