FedInvent™ Patents
Patent Details for Tuesday, February 04, 2020
This page was updated on Monday, March 27, 2023 at 06:00 AM GMT
Department of Health and Human Services (HHS)
| US 10548474 | Dana et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| INVENTOR(S) | Reza Dana (Newton, Massachusetts); Francisco L. Amparo Pulido (Cambridge, Massachusetts); Haobing Wang (Newton, Massachusetts) |
| ABSTRACT | The present application includes methods, systems and computer readable storage devices for determining a color score for at least a portion of a biological tissue. The subject matter of the application is embodied in a method that includes obtaining a digital image of the biological tissue, and receiving a selection of a portion of the image as an evaluation area. The method also includes determining for each of a plurality of pixels within the evaluation area, a plurality of color components that are based on a Cartesian color space, and determining, from the color components, a hue value in a polar coordinate based color space. The method further includes determining a color value based on the hue value for each of the plurality of pixels, and assigning a color score to the evaluation area based on an average of the color values of the plurality of pixels. |
| FILED | Thursday, December 28, 2017 |
| APPL NO | 15/856134 |
| ART UNIT | 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/90 (20170101) G06T 2207/30041 (20130101) Pictorial Communication, e.g Television H04N 1/628 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548479 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zhongping Chen (Irivne, California); Jiang Zhu (Irvine, California) |
| ABSTRACT | A system for imaging and quantifying shear wave and shear modulus under orthogonal acoustic radiation force (ARF) excitation using the OCT Doppler variance apparatus. The ARF perpendicular or with at least a perpendicular component to the OCT beam is produced by a remote ultrasonic transducer. The OCT Doppler variance apparatus, which is sensitive to the transverse vibration, is used to measure the ARF induced vibration. For analysis of the shear modulus, the Doppler variance apparatus is utilized to visualize shear wave propagation. The propagation velocity of the shear wave is measured and then used to quantitatively map the shear modulus. |
| FILED | Saturday, February 13, 2016 |
| APPL NO | 15/043539 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) A61B 5/0066 (20130101) Original (OR) Class A61B 5/0084 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548505 | Rothgang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Siemens Healthcare GmbH (Erlangen, Germany); The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | Siemens Healthcare GmbH (Erlangen, Germany); The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Eva Rothgang (Nürnberg, Germany); Arne Hengerer (Möhrendorf, Germany); Lars Lauer (Neunkirchen, Germany); Jan Fritz (Baltimore, Maryland); Paul Bottomley (Columbia, Maryland); Wesley David Gilson (Northbeach, Maryland); Robert Grimm (Nürnberg, Germany) |
| ABSTRACT | A magnetic resonance method and system are provided for magnetic resonance (MR) image-guided insertion of an object into a biological tissue along a predetermined trajectory. The trajectory provides a path between a starting point and a target site within the tissue. Sufficiently high resolution images can be generated in real time to precisely guide the needle placement. A compressed sensing approach is used to generate the images based on minimization of a cost function, where the cost function is based on the predetermined needle path, artifact effects associated with the needle, the negligible changes in the images away from the trajectory, and the limited differences between successive images. The improved combination of spatial and temporal resolution facilitates an insertion procedure that can be continuously adjusted to accurately follow a predetermined trajectory in the tissue, without interruptions to obtain verification images. |
| FILED | Tuesday, March 15, 2016 |
| APPL NO | 15/070116 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548523 | Ahmadi et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Mahdi Ahmadi (Minneapolis, Minnesota); Rajesh Rajamani (Saint Paul, Minnesota); Gerald Timm (Minneapolis, Minnesota) |
| ABSTRACT | A pressure sensing catheter system includes a urethral catheter and a sensor array formed on the urethral catheter. The sensor array includes a plurality of pressure sensors distributed along a length of the urethral catheter. The sensor array is configured to produce a dynamic pressure distribution profile along a urethra. |
| FILED | Wednesday, April 08, 2015 |
| APPL NO | 14/681476 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/205 (20130101) Original (OR) Class A61B 5/0492 (20130101) A61B 5/04882 (20130101) A61B 5/6853 (20130101) A61B 5/7203 (20130101) A61B 2560/0261 (20130101) A61B 2562/043 (20130101) A61B 2562/063 (20130101) A61B 2562/0214 (20130101) A61B 2562/0247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548544 | Furenlid et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Lars R. Furenlid (Tucson, Arizona); Xin Li (Tucson, Arizona) |
| ABSTRACT | A method for forming an optimized image of a subject includes steps of acquiring a plurality of one-dimensional images, generating a measured sinogram from the plurality of one-dimensional images, and determining a plurality of trial images. In the step of acquiring, the method acquires a plurality of one-dimensional images of the subject captured by a rotating-slit imager having (a) a detector, and (b) a slit collimator having a slit oriented at one of a respective plurality of slit-rotation angles, relative to the subject, about a longitudinal axis substantially perpendicular to a front surface of the detector. In the step of determining, the method iteratively determines a plurality of trial images each having a respective trial sinogram. The optimized image is one of the plurality of trial images and its corresponding trial sinogram differs from the measured sinogram by less than a predetermined tolerance. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/773691 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/06 (20130101) A61B 6/037 (20130101) A61B 6/4258 (20130101) Original (OR) Class A61B 6/4275 (20130101) A61B 6/5205 (20130101) Image Data Processing or Generation, in General G06T 11/003 (20130101) G06T 11/006 (20130101) G06T 2211/424 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548549 | Boone et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | John M. Boone (Folsom, California); Thomas R. Yellen-Nelson (Del Mar, California) |
| ABSTRACT | A device and methods for performing a simulated CT biopsy on a region of interest on a patient. The device comprises a gantry (22) configured to mount an x-ray emitter (24) and CT detector (26) on opposing sides of the gantry, a motor (28) rotatably coupled to the gantry such that the gantry rotates horizontally about the region of interest, and a high resolution x-ray detector (172) positioned adjacent the CT detector in between the CT detector and the x-ray emitter. |
| FILED | Friday, August 04, 2017 |
| APPL NO | 15/669829 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/03 (20130101) A61B 6/12 (20130101) A61B 6/037 (20130101) A61B 6/405 (20130101) A61B 6/0435 (20130101) A61B 6/482 (20130101) Original (OR) Class A61B 6/502 (20130101) A61B 6/584 (20130101) A61B 6/4028 (20130101) A61B 6/4417 (20130101) A61B 6/4423 (20130101) A61B 6/5235 (20130101) A61B 8/0825 (20130101) A61B 8/4416 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548564 | Mauldin, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rivanna Medical LLC (Charlottesville, Virginia) |
| ASSIGNEE(S) | Rivanna Medical, LLC (Charlottesville, Virginia) |
| INVENTOR(S) | Frank William Mauldin, Jr. (Charlottesville, Virginia); Kevin Owen (Crozet, Virginia) |
| ABSTRACT | Systems and methods for processing ultrasound data are provided. The disclosure includes using at least one computer hardware processor to perform obtaining ultrasound data generated based, at least in part, on one or more ultrasound signals from an imaged region of a subject, the ultrasound data comprising fundamental frequency ultrasound data and harmonic frequency ultrasound data, calculating shadow intensity data based at least in part on the harmonic frequency ultrasound data, generating, based at least in part on the fundamental frequency ultrasound data, an indication of bone presence in the imaged region, generating, based at least in part on the shadow intensity data, an indication of tissue presence in the imaged region, and generating an ultrasound image of the subject at least in part by combining the indication of bone presence and the indication of tissue presence. |
| FILED | Tuesday, February 16, 2016 |
| APPL NO | 15/044425 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/461 (20130101) A61B 8/0875 (20130101) Original (OR) Class A61B 8/4254 (20130101) A61B 8/5207 (20130101) A61B 8/5223 (20130101) A61B 8/5269 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548628 | Swaney et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Philip J. Swaney (Nashville, Tennessee); Robert J. Webster, III (Nashville, Tennessee) |
| ABSTRACT | A steerable surgical needle (10) includes an elongated needle shaft (12), a beveled tip portion (14), and a flexural element (16) that connects the needle shaft (12) with the tip portion (14) and permits the tip portion to deflect relative to the needle shaft. A method for steering the surgical needle (10) through tissue includes the steps of advancing the needle in the body tissue to induce tip flexure which causes the needle to follow a curved trajectory, and rotating the needle about its longitudinal axis in place, without advancement, to remove the tip flexure. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/208508 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3403 (20130101) Original (OR) Class A61B 17/3417 (20130101) A61B 2017/003 (20130101) A61B 2017/3454 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548842 | Vivas-Mejia et al. |
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| FUNDED BY |
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| APPLICANT(S) | Pablo E. Vivas-Mejia (San Juan, Puerto Rico); Jeyshka M. Reyes Gonzalez (San Juan, Puerto Rico); Anil K. Sood (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pablo E. Vivas-Mejia (San Juan, Puerto Rico); Jeyshka M. Reyes Gonzalez (San Juan, Puerto Rico); Anil K. Sood (Houston, Texas) |
| ABSTRACT | The present invention discloses c-MYC-siRNA formulation as a potential therapeutic target for cisplatin-resistant ovarian cancer. It is disclosed targeting c-MYC with small interfering RNA (siRNA) in the cisplatin-resistant ovarian cancer cell line inducing a significant cell growth arrest and inhibition of cell proliferation. Apoptosis and arrest of cell cycle progression were also observed after c-MYC-siRNA-based silencing of c-MYC. Furthermore, delivering nanoliposomal c-MYC-siRNA, decreased tumor weight and number of tumor nodules compared with a liposomal-negative control siRNA. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 15/899682 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1271 (20130101) A61K 9/1272 (20130101) Original (OR) Class A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 33/24 (20130101) A61K 33/24 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548852 | Bayley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oxford University Innovation Limited (Oxford, United Kingdom) |
| ASSIGNEE(S) | Oxford University Innovation Limited (Botley, Oxford, United Kingdom) |
| INVENTOR(S) | John Hagan Pryce Bayley (Oxford, United Kingdom); Andrew Heron (Oxford, United Kingdom); Gabriel Villar (Oxford, United Kingdom) |
| ABSTRACT | The invention provides a droplet encapsulate comprising: a drop of a hydrophobic medium; a peripheral layer of non-polymeric amphipathic molecules around the surface of the drop; and an aqueous droplet within the peripheral layer, the aqueous droplet comprising: (a) an aqueous medium and (b) an outer layer of non-polymeric amphipathic molecules around the surface of the aqueous medium. The invention also provides processes for preparing the droplet encapsulates. Various uses of the droplet encapsulates are also described, including their use as drug delivery vehicles, in synthetic biology, and in the study of membrane proteins. |
| FILED | Friday, November 02, 2012 |
| APPL NO | 14/354706 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/50 (20130101) Original (OR) Class A61K 31/085 (20130101) A61K 49/0002 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/02 (20130101) B01J 13/025 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2984 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10548858 — Inhibition of sphingosine 1-phosphate receptor for treatment and prevention of lymphedema
| US 10548858 | Mehrara |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Babak Mehrara (Chappaqua, New York) |
| ABSTRACT | Provided are methods of and compositions for treating or preventing lymphedema by administering a sphingosine 1-phoshate receptor modulator. |
| FILED | Thursday, August 17, 2017 |
| APPL NO | 16/326272 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/137 (20130101) Original (OR) Class A61K 31/137 (20130101) A61K 31/397 (20130101) A61K 31/397 (20130101) A61K 31/421 (20130101) A61K 31/421 (20130101) A61K 31/426 (20130101) A61K 31/426 (20130101) A61K 31/4245 (20130101) A61K 31/4245 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) A61P 7/10 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 2405/08 (20130101) G01N 2500/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548860 | Nicolls et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Board Of Trustees of The Leland Stanford Junior University (Stanford, California); The United States Government as Represented By The Department Of Veterans Affairs (Washington, District of Columbia); The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Mark R. Nicolls (Palo Alto, California); Jayakumar Rajadas (Cupertino, California); Geoffrey C. Gurtner (Woodside, California); Xinguo Jiang (Palo Alto, California); Gundeep Dhillon (Stanford, California); Gregg L. Semenza (Reisterstown, Maryland) |
| ABSTRACT | Formulations and methods are provided for improving the function, i.e. clinical outcome, of solid organ transplants. Lung transplantation is of particular interest. In the methods of the invention, a nanoparticle formulation comprising an effective dose of an iron chelator active agent in nanoparticle form, including without limitation, deferoxamine (DFO), deferasirox (DFX), and deferiprone (DFP), etc. suspended in a carrier compatible with the tissue of interest, is topically applied to the surface of tissues at the site of anastomosis. The nanoparticles are comprised of the active agent and a pharmaceutically acceptable stabilizer. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/260989 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 9/5138 (20130101) A61K 9/5146 (20130101) A61K 9/5161 (20130101) A61K 9/5169 (20130101) A61K 31/164 (20130101) Original (OR) Class A61K 31/436 (20130101) A61K 31/4196 (20130101) A61K 31/4412 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548864 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Pinteon Therapeutics, Inc. (Concord, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kun Ping Lu (Newton, Massachusetts); Xiao Zhen Zhou (Newton, Massachusetts); Shuo Wei (Chestnut Hill, Massachusetts); Lijun Sun (Harvard, Massachusetts); Michelle Lynn Hall (Somerville, Massachusetts) |
| ABSTRACT | The invention features all-trans retinoic acid (ATRA)-related compounds capable of associating with Pin1 and methods of treating a proliferative disorder characterized by elevated Pin1 marker levels, Pin1 degradation, and/or reduced Pin1 Ser71 phosphorylation in a subject by administering an ATRA-related compound. The invention also features methods of treating proliferative disorders, autoimmune diseases, and addiction conditions (e.g., diseases, disorders, and conditions characterized by elevated Pin1 marker levels) by administering an ATRA-related compound in combination with another therapeutic compound. |
| FILED | Thursday, March 10, 2016 |
| APPL NO | 15/557731 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) A61K 31/196 (20130101) Original (OR) Class A61K 31/203 (20130101) A61K 31/452 (20130101) A61K 31/4152 (20130101) A61K 31/4166 (20130101) A61K 31/4192 (20130101) A61K 31/4196 (20130101) A61K 31/4245 (20130101) A61K 31/5375 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548893 | Wise et al. |
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| FUNDED BY |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas) |
| INVENTOR(S) | John G. Wise (Dallas, Texas); Pia D. Vogel (Dallas, Texas); Frances K. Brewer (Waxahachie, Texas); Courtney A. Follit (Dallas, Texas) |
| ABSTRACT | The present disclosure provides a method of treating a subject that is resistant to one or more drugs by identifying a subject having one or more drug resistant cells; administering to the subject a pharmaceutically effective amount of an inhibitor compound, and contacting one or more drug resistant cells with the inhibitor compound to reduce the export of the inhibitor compound from the one or more drug resistant tumor cells and to block the transport of drug(s) from the one or more drug resistant cells. |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/204582 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) A61K 31/353 (20130101) A61K 31/4196 (20130101) A61K 31/4525 (20130101) A61K 31/5025 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548897 | Dar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Arvin Dar (New York, New York); Neil Dhawan (New York, New York); Alex P. Scopton (New York, New York) |
| ABSTRACT | This invention relates to antagonists of Kinase Suppressor of Ras (KSR). Pharmaceutical compositions comprising KSR inhibitors and methods of treating cancer are also provided. |
| FILED | Friday, April 15, 2016 |
| APPL NO | 15/566565 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Original (OR) Class A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548911 | Phipps et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Richard P. Phipps (Pittsford, New York); Collynn Woeller (Webster, New York) |
| ABSTRACT | Disclosed are methods of treating fibrosis in a patient in need thereof that includes administering to the patient an amount of an active agent, as identified herein, that is therapeutically effective to inhibit myofibroblast formation and thereby treat the fibrosis. Also disclosed is a recombinant cell line that includes a recombinant gene that expresses a detectable expression product in a dose-dependent response to TGFβ, as well as methods of identifying a compound that inhibits TGFβ-mediated expression of the detectable expression product. |
| FILED | Tuesday, June 16, 2015 |
| APPL NO | 15/319254 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/166 (20130101) A61K 31/167 (20130101) A61K 31/341 (20130101) A61K 31/351 (20130101) A61K 31/381 (20130101) A61K 31/415 (20130101) A61K 31/519 (20130101) A61K 31/549 (20130101) A61K 31/551 (20130101) A61K 31/635 (20130101) A61K 31/4184 (20130101) A61K 31/4409 (20130101) A61K 31/4412 (20130101) A61K 31/5375 (20130101) A61K 31/7048 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548930 | Deng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Liang Deng (New York, New York); Jedd Wolchok (New York, New York); Taha Merghoub (New York, New York); Stewart Shuman (New York, New York); Peihong Dai (New York, New York); Weiyi Wang (New York, New York) |
| ABSTRACT | The present disclosure relates to modified vaccinia Ankara (MVA) virus or MVAAE3L delivered intratumorally or systemically as an anticancer immunotherapeutic agent, alone, or in combination with one or more immune checkpoint blocking agents for the treatment of malignant solid tumors. Particular embodiments relate to mobilizing the host's immune system to mount an immune response against the tumor. |
| FILED | Monday, April 18, 2016 |
| APPL NO | 15/565609 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/768 (20130101) Original (OR) Class A61K 39/12 (20130101) A61K 39/3955 (20130101) A61K 39/3955 (20130101) A61K 2039/54 (20130101) A61K 2039/57 (20130101) A61K 2039/505 (20130101) A61K 2039/525 (20130101) A61K 2039/545 (20130101) A61K 2039/5254 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24122 (20130101) C12N 2710/24132 (20130101) C12N 2710/24134 (20130101) C12N 2710/24171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548944 | Jaynes et al. |
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| FUNDED BY |
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| APPLICANT(S) | Riptide Bioscience, Inc. (Vallejo, California) |
| ASSIGNEE(S) | Riptide Bioscience, Inc. (Vallejo, California) |
| INVENTOR(S) | Jesse Jaynes (Auburn, Alabama); L. Edward Clemens (Sacramento, California); Henry Willfred Lopez (Napa, California); George R. Martin (Rockville, Maryland); Kathryn Woodburn (Saratoga, California) |
| ABSTRACT | Aspects of the present invention relate to peptides having antimicrobial activity. In certain aspects, the invention relates to peptides having potent antimicrobial activity, broad-spectrum antimicrobial activity, and/or the ability to kill otherwise antibiotic-resistant microbes, or microbes protected by biofilms. |
| FILED | Friday, October 19, 2018 |
| APPL NO | 16/165727 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0053 (20130101) A61K 9/0073 (20130101) A61K 38/10 (20130101) Original (OR) Class A61K 38/16 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 31/10 (20180101) Peptides C07K 7/08 (20130101) C07K 14/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548949 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Feinstein Institute for Medical Research (Manhasset, New York) |
| ASSIGNEE(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| INVENTOR(S) | Haichao Wang (Edison, New Jersey); Wei Li (Plainview, New York); Kevin J. Tracey (Old Greenwich, Connecticut); Ping Wang (Roslyn, New York) |
| ABSTRACT | Methods of treating sepsis or endotoxemia in a subject comprising administering to the subject an amount of an antagonist of a Panx1 hemichannel protein or an amount of an antagonist of a Cx43 hemichannel protein. |
| FILED | Wednesday, August 03, 2016 |
| APPL NO | 15/748776 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/22 (20130101) A61K 31/704 (20130101) A61K 38/177 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/02 (20180101) A61P 37/02 (20180101) Peptides C07K 16/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548950 | Trujillo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kristina Trujillo (Placitas, New Mexico); Nicholas Patrick Gannon (Albuquerque, New Mexico); Roger Alan Vaughan (High Point, North Carolina) |
| ABSTRACT | In one embodiment, the invention provides methods of treating or preventing cancer, in particular aspects breast and/or prostate cancer, by administering to a subject in need thereof a therapeutically-effective amount of irisin and, optionally, one or more adjuvant therapies (e.g. synergistic co-administration of an additional anti-cancer agent or chemotherapy). Related pharmaceutical compositions, assays and kits are also provided. |
| FILED | Wednesday, November 18, 2015 |
| APPL NO | 15/528348 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/704 (20130101) A61K 38/22 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548957 | Cantor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Harvey Cantor (Boston, Massachusetts); Hye-Jung Kim (Brookline, Massachusetts); Jianmei Wu Leavenworth (Hoover, Alabama) |
| ABSTRACT | Nanoparticles to treat autoimmune diseases and HIV infection are provided. The nanoparticles comprise a biocompatible polymer and a complex, wherein the complex is a major histocompatibility complex (MHC) class I antigen E (HLA-E) linked to a peptide, and wherein the HLA-E-peptide complex is linked to the surface of the nanoparticle. The present invention also relates to methods for treating autoimmune diseases and HIV infection. |
| FILED | Thursday, September 26, 2013 |
| APPL NO | 14/431113 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0008 (20130101) Original (OR) Class A61K 2039/58 (20130101) A61K 2039/5154 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/47 (20130101) C07K 14/70539 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2501/2315 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548959 | Khan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambirdge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Omar F. Khan (Cambridge, Massachusetts); Jasdave S. Chahal (Arlington, Massachusetts); Daniel G. Anderson (Framington, Massachusetts); Hidde Ploegh (Brookline, Massachusetts); Robert S. Langer (Newton, Massachusetts); Tyler E. Jacks (Newton, Massachusetts); David A. Canner (Cambridge, Massachusetts) |
| ABSTRACT | Compositions and methods for modified dendrimer nanoparticle (“MDNP”) delivery of therapeutic, prophylactic and/or diagnostic agent such as large repRNA molecules to the cells of a subject have been developed. MDNPs efficiently drive proliferation of antigen-specific T cells against intracellular antigen, and potentiate antigen-specific antibody responses. MDNPs can be multiplexed to deliver two or more different repRNAs to modify expression kinetics of encoded antigens and to simultaneous deliver repRNAs and mRNAs including the same UTR elements that promote expression of encoded antigens. |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/274954 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 39/0012 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548970 | Jiang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH and HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH and HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Baoming Jiang (Duluth, Georgia); Yuhuan Wang (Liburn, Georgia) |
| ABSTRACT | Attenuated G9P[6] rotavirus is disclosed herein. In some embodiments, pharmaceutical compositions are disclosed that include an attenuated G9P[6] rotavirus, or a component thereof. These compositions can be used to induce an immune response, such as a protective immune response, to a rotavirus. The compositions can be used as vaccines, such as for children (infants), for example in a prime boost strategy. |
| FILED | Wednesday, September 28, 2016 |
| APPL NO | 15/765716 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 39/15 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/54 (20130101) A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) A61K 2039/55505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2720/12021 (20130101) C12N 2720/12034 (20130101) C12N 2720/12043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548983 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Jianjun Wang (Troy, Michigan); Qianqian Li (Troy, Michigan); Michael Chopp (Southfield, Michigan); Feng Jiang (Troy, Michigan); Guojun Wu (Northville, Michigan) |
| ABSTRACT | Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject. |
| FILED | Tuesday, September 04, 2018 |
| APPL NO | 16/120829 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/00 (20130101) A61K 38/1709 (20130101) A61K 47/59 (20170801) Original (OR) Class A61K 47/543 (20170801) A61K 48/0041 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/605 (20130101) C12N 2502/30 (20130101) C12N 2506/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548987 | Dimitrov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Dimiter S. Dimitrov (Frederick, Maryland); Yang Feng (Frederick, Maryland); John M. Maris (Philadelphia, Pennsylvania); Zhongyu Zhu (Frederick, Maryland); Robyn Tovah Sussman (Philadelphia, Pennsylvania) |
| ABSTRACT | The identification and characterization of two fully human CD56-specific monoclonal antibodies targeting spatially separated epitopes proximal and distal to the plasma membrane is described. Also described are antibody-drug conjugates (ADCs) of the identified antibodies and their use for targeting CD56-expressing tumor cells. |
| FILED | Friday, July 29, 2016 |
| APPL NO | 15/747620 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6803 (20170801) Original (OR) Class A61K 47/6851 (20170801) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 2317/21 (20130101) C07K 2317/732 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548989 | Bradbury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Cornell University (Ithaca, New York); The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Cornell University (Ithaca, New York); The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Michelle S. Bradbury (New York, New York); Thomas P. Quinn (Columbia, Missouri); Feng Chen (New York, New York); Barney Yoo (New York, New York); Jason Lewis (New York, New York); Ulrich Wiesner (Ithaca, New York); Kai Ma (Ithaca, New York) |
| ABSTRACT | Disclosed herein are nanoparticle immunoconjugates useful for therapeutics and/or diagnostics. The immunoconjugates have diameter (e.g., average diameter) no greater than 20 nanometers (e.g., as measured by dynamic light scattering (DLS) in aqueous solution, e.g., saline solution). In certain embodiments, the conjugates are silica-based nanoparticles with single chain antibody fragments attached thereto. |
| FILED | Thursday, April 07, 2016 |
| APPL NO | 15/564315 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/6923 (20170801) Original (OR) Class A61K 49/0058 (20130101) A61K 49/1824 (20130101) A61K 51/1093 (20130101) A61K 51/1251 (20130101) Peptides C07K 16/40 (20130101) C07K 2317/55 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548993 | Xie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| ASSIGNEE(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| INVENTOR(S) | Jin Xie (Athens, Georgia); Hongmin Chen (Athens, Georgia); Geoffrey D. Wang (Athens, Georgia) |
| ABSTRACT | Nanoparticles described as metal-encapsulated carbonaceous dots or M@C-dots are disclosed. Also disclosed are specific M@C-dots with gadolinium, so called Gd@C-dots. These nanoparticles are biologically inert and preclude the release of metal in biological environments. In addition, despite a dimension exceeding the commonly recognized threshold for renal clearance, the disclosed nanoparticles can be efficiently cleared via urine after systematic injection. Methods of making and using such nanoparticles are also disclosed. |
| FILED | Thursday, July 30, 2015 |
| APPL NO | 15/500691 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/055 (20130101) A61B 5/0071 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/1827 (20130101) A61K 49/1866 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5601 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548994 | Milligan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Erin Damita Milligan (Placitas, New Mexico); Jeffrey P. Norenberg (Albuquerque, New Mexico) |
| ABSTRACT | In one embodiment, the invention provides a method of treating a subject suffering from chronic neuropathic pain and/or allodynia by administering a therapeutically-effective amount of at least one LFA1 antagonist to the subject. In a preferred embodiment, the invention provides a method of treating a subject suffering from chronic neuropathic pain and/or allodynia, the method comprising administering intrathecally to the subject a therapeutically-effective amount of microparticles comprising PLGA-encapsulated pDNA-IL-10, optionally in combination with a therapeutically-effective amount of intrathecally-administered CpG oligodeoxynucleotide (CpG ODN) and/or at least one LFA1 antagonist. |
| FILED | Tuesday, March 04, 2014 |
| APPL NO | 14/196343 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4174 (20130101) A61K 38/34 (20130101) A61K 38/1841 (20130101) A61K 38/2013 (20130101) A61K 38/2026 (20130101) A61K 38/2066 (20130101) A61K 38/2086 (20130101) A61K 51/0453 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548997 | Bradbury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sloan-Kettering Institute for Cancer Research (New York, New York); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York); Cornell University (Ithaca, New York) |
| INVENTOR(S) | Michelle S. Bradbury (New York, New York); Ulrich Wiesner (Ithaca, New York); Oula Penate Medina (Kiel, Germany); Hooisweng Ow (Woburn, Massachusetts); Andrew Burns (Niskayuna, New York); Jason S. Lewis (New York, New York); Steven M. Larson (New York, New York) |
| ABSTRACT | The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1 nm and about 25 nm, between about 1 nm and about 15 nm, or between about 1 nm and about 8 nm. The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound. The nanoparticle also exhibits high biostability and biocompatibility. To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as poly(ethylene glycol) (PEG). The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo. In order to target a specific cell type, the nanoparticle may further be conjugated to a ligand, which is capable of binding to a cellular component associated with the specific cell type, such as a tumor marker. In one embodiment, a therapeutic agent may be attached to the nanoparticle. To permit the nanoparticle to be detectable by not only optical fluorescence imaging, but also other imaging techniques, such as positron emission tomography (PET), single photon emission computed tomography (SPECT), computerized tomography (CT), bioluminescence imaging, and magnetic resonance imaging (MRI), radionuclides/radiometals or paramagnetic ions may be conjugated to the nanoparticle. |
| FILED | Wednesday, March 01, 2017 |
| APPL NO | 15/446319 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5115 (20130101) A61K 9/5146 (20130101) A61K 9/5169 (20130101) A61K 49/0019 (20130101) A61K 49/0032 (20130101) A61K 49/0054 (20130101) A61K 49/0056 (20130101) A61K 49/0093 (20130101) A61K 51/08 (20130101) A61K 51/082 (20130101) A61K 51/086 (20130101) A61K 51/1244 (20130101) Original (OR) Class A61K 51/1255 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/552 (20130101) G01N 33/574 (20130101) G01N 33/582 (20130101) G01N 33/587 (20130101) G01N 33/54346 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/927 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548998 | Bradbury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sloan-Kettering Institute for Cancer Research (New York, New York); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York); Cornell University (Ithaca, New York) |
| INVENTOR(S) | Michelle S. Bradbury (New York, New York); Ulrich Wiesner (Ithaca, New York); Oula Penate Medina (Kiel, Germany); Andrew Burns (Niskayuna, New York); Jason S. Lewis (New York, New York); Steven M. Larson (New York, New York) |
| ABSTRACT | The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1 nm and about 25 nm, between about 1 nm and about 15 nm, or between about 1 nm and about 8 nm. The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound. The nanoparticle also exhibits high biostability and biocompatibility. To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as poly(ethylene glycol) (PEG). The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo. In order to target a specific cell type, the nanoparticle may further be conjugated to a ligand, which is capable of binding to a cellular component associated with the specific cell type, such as a tumor marker. In one embodiment, a therapeutic agent may be attached to the nanoparticle. To permit the nanoparticle to be detectable by not only optical fluorescence imaging, but also other imaging techniques, such as positron emission tomography (PET), single photon emission computed tomography (SPECT), computerized tomography (CT), bioluminescence imaging, and magnetic resonance imaging (MRI), radionuclides/radiometals or paramagnetic ions may be conjugated to the nanoparticle. |
| FILED | Friday, June 15, 2018 |
| APPL NO | 16/009267 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) A61K 49/0093 (20130101) A61K 51/1244 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/552 (20130101) G01N 33/574 (20130101) G01N 33/582 (20130101) G01N 33/587 (20130101) G01N 33/54346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549022 | Jeffries et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Richard Garrett Jeffries (Philadelphia, Pennsylvania); William J. Federspiel (Pittsburgh, Pennsylvania); Brian Joseph Frankowski (Imperial, Pennsylvania) |
| ABSTRACT | An extracorporeal gas exchange device includes a housing, a rigid shaft rotatable within the housing, a plurality of agitation mechanisms positioned on the rigid shaft, and a plurality of hollow gas permeable fibers adapted to permit diffusion of gas between fluid flowing within the housing and an interior of the plurality of hollow gas permeable fibers. The plurality of hollow gas permeable fibers are positioned radially outward from the plurality of agitation mechanisms. The rotational speed of the rigid shaft is adjustable independent of the flow rate of fluid through the housing. |
| FILED | Wednesday, January 20, 2016 |
| APPL NO | 15/542532 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/101 (20130101) A61M 1/262 (20140204) Original (OR) Class A61M 1/267 (20140204) A61M 1/1006 (20140204) A61M 1/1086 (20130101) A61M 1/1698 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549108 | Efimov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | The Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Igor R. Efimov (Wildwood, Missouri); Valentin Krinski (Villeneuve Loubet, France); Vladmir P. Nikolski (St. Anthony, Minnesota) |
| ABSTRACT | A method for extinguishing a cardiac arrhythmia utilizes destructive interference of the passing of the reentry wave tip of an anatomical reentry through a depolarized region created by a relatively low voltage electric field in such a way as to effectively unpin the anatomical reentry. Preferably, the relatively low voltage electric field is defined by at least one unpinning shock(s) that are lower than an expected lower limit of vulnerability as established, for example, by a defibrillation threshold test. By understanding the physics of the electric field distribution between cardiac cells, the method permits the delivery of an electric field sufficient to unpin the core of the anatomical reentry, whether the precise or estimated location of the reentry is known or unknown and without the risk of inducting ventricular fibrillation. A number of embodiments for performing the method are disclosed. |
| FILED | Monday, August 27, 2018 |
| APPL NO | 16/113692 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0402 (20130101) A61B 5/0464 (20130101) A61B 5/7239 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/39 (20130101) A61N 1/3627 (20130101) A61N 1/3906 (20130101) A61N 1/3925 (20130101) A61N 1/3962 (20130101) A61N 1/3987 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549121 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina); The University of North Carolina at Charlotte (Charlotte, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina); The University of North Carolina at Charlotte (Charlotte, North Carolina) |
| INVENTOR(S) | Qingrong Jackie Wu (Durham, North Carolina); Yaorong Ge (Matthews, North Carolina); Fang-Fang Yin (Durham, North Carolina); Lulin Yuan (Durham, North Carolina) |
| ABSTRACT | Systems and methods for efficient and automatic determination of radiation beam configurations for patient-specific radiation therapy planning are disclosed. According to an aspect, a method includes receiving data based on patient information and geometric characterization of one or more organs at risk proximate to a target volume of a patient. The method includes determining automatically one or more radiation treatment beam configuration sets. Further, the method includes presenting the determined one or more radiation beam configuration sets via a user interface. |
| FILED | Monday, March 07, 2016 |
| APPL NO | 15/555489 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1031 (20130101) A61N 5/1038 (20130101) Original (OR) Class A61N 5/1039 (20130101) A61N 5/1077 (20130101) A61N 2005/1041 (20130101) A61N 2005/1074 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550070 | Malkas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Linda H. Malkas (Duarte, California); David Horne (Altadena, California); Robert J. Hickey (Duarte, California); Long Gu (Duarte, California) |
| ABSTRACT | Described herein, inter alia, are compositions of PCNA modulators and methods for treating or preventing cancer. |
| FILED | Friday, September 16, 2016 |
| APPL NO | 15/760959 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/4409 (20130101) A61K 33/24 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Acyclic or Carbocyclic Compounds C07C 233/76 (20130101) Original (OR) Class Heterocyclic Compounds C07D 213/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550071 | Evans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California); Mitobridge, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California); Mitobridge, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Ronald M. Evans (La Jolla, California); Michael Downes (La Jolla, California); Thomas J. Baiga (La Jolla, California); Joseph P. Noel (La Jolla, California); Emi Kanakubo Embler (Tustin, California); Weiwei Fan (La Jolla, California); John F. W. Keana (Eugene, Oregon); Mark G. Bock (Boston, Massachusetts); Arthur F. Kluge (Lincoln, Massachusetts); Mike A. Patane (Andover, Massachusetts) |
| ABSTRACT | Provided herein are compounds and compositions useful in increasing PPARδ activity. The compounds and compositions provided herein are useful for the treatment of PPARδ related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases). |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/897796 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/164 (20130101) A61K 31/341 (20130101) A61K 31/381 (20130101) A61K 31/422 (20130101) A61K 31/427 (20130101) A61K 31/4025 (20130101) A61K 31/4178 (20130101) A61K 31/5377 (20130101) Acyclic or Carbocyclic Compounds C07C 233/73 (20130101) C07C 233/87 (20130101) Original (OR) Class C07C 235/42 (20130101) C07C 235/48 (20130101) C07C 235/84 (20130101) C07C 237/22 (20130101) C07C 237/32 (20130101) C07C 237/48 (20130101) C07C 255/57 (20130101) C07C 259/06 (20130101) C07C 317/44 (20130101) C07C 2601/02 (20170501) Heterocyclic Compounds C07D 207/04 (20130101) C07D 209/34 (20130101) C07D 213/56 (20130101) C07D 231/12 (20130101) C07D 271/12 (20130101) C07D 295/13 (20130101) C07D 305/06 (20130101) C07D 307/54 (20130101) C07D 307/83 (20130101) C07D 309/06 (20130101) C07D 333/24 (20130101) C07D 405/04 (20130101) C07D 405/10 (20130101) C07D 405/12 (20130101) C07D 407/12 (20130101) C07D 413/04 (20130101) C07D 413/10 (20130101) C07D 413/12 (20130101) C07D 417/04 (20130101) C07D 417/10 (20130101) C07D 417/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550074 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina); THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Pei Zhou (Durham, North Carolina); Eric J. Toone (Durham, North Carolina); Robert A. Nicholas (Chapel Hill, North Carolina); Ramesh Gopalaswamy (Durham, North Carolina); Xiaofei Liang (Durham, North Carolina); Frank Navas, III (Durham, North Carolina) |
| ABSTRACT | Disclosed are compounds of formulae: and pharmaceutically acceptable salts thereof, wherein the variables, R1, R2, R3, R4, R5, R6, R7, R11, R12, R13, R14, R15, R16, R17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds. |
| FILED | Thursday, February 07, 2019 |
| APPL NO | 16/270291 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic or Carbocyclic Compounds C07C 259/06 (20130101) Original (OR) Class C07C 259/18 (20130101) C07C 311/06 (20130101) C07C 317/18 (20130101) C07C 317/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550093 | Ojima et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Iwao Ojima (Port Jefferson, New York); Changwei Wang (Port Jefferson Station, New York); Xin Wang (Centereach, New York) |
| ABSTRACT | The invention includes taxoid compounds represented by the formula: wherein: R1 represents a methyl group or a fluorine; R2 represents an alkyl or alkenyl group having one to six carbon atoms; or a cycloalkyl or cycloalkenyl group having three to seven ring carbon atoms; R3 represents an alkyl, alkenyl, dialkylamino, alkylamino, or alkoxy group having one to six carbon atoms; a cycloalkyl or cycloalkenyl group having three to seven ring carbon atoms; an aryl group having six to eighteen ring carbon atoms; or a heteroaryl group having three to seventeen ring carbon atoms; R4 represents hydrogen or a methyl group; and X represents hydrogen or fluorine. |
| FILED | Friday, July 01, 2016 |
| APPL NO | 15/740859 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 305/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550108 | Tulin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Institute for Cancer Research (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Alexei Tulin (Philadelphia, Pennsylvania) |
| ABSTRACT | Compounds that are not related to NAD, and which target PARP1-histone H4 interaction are provided, as well as compositions of these compounds, and methods for specific inhibition of poly(ADP-ribose) polymerase 1 (PARP-1) using these compounds are provided. These PARP-1 inhibitors may be used to treat cancer in which PARP-1 activation or biologic activity plays a role, including prostate cancer, breast cancer, kidney cancer, ovarian cancer, lymphoma, leukemia, and glioblastoma, among others. |
| FILED | Wednesday, September 30, 2015 |
| APPL NO | 15/515773 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 207/06 (20130101) C07D 263/04 (20130101) C07D 295/15 (20130101) C07D 317/28 (20130101) C07D 317/72 (20130101) C07D 319/06 (20130101) C07D 405/06 (20130101) C07D 405/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550112 | Gray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael S. Gray (Boston, Massachusetts); Jaebong Jang (Brookline, Massachusetts); Pasi Janne (Needham, Massachusetts) |
| ABSTRACT | The application relates to a compound having Formula (I′): which modulates the activity of EGFR, a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease in which EGFR plays a role. |
| FILED | Wednesday, July 20, 2016 |
| APPL NO | 15/742113 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 403/14 (20130101) C07D 409/14 (20130101) C07D 413/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550121 | Gray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael S. Gray (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Nicholas Paul Kwiatkowski (Brookline, Massachusetts) |
| ABSTRACT | The present invention provides novel compounds of Formula (I), (II), or (III), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating and/or preventing proliferative diseases (e.g., cancers (e.g., leukemia, acute lymphoblastic leukemia, lymphoma, Burkitt's lymphoma, melanoma, multiple myeloma, breast cancer, Ewing's sarcoma, osteosarcoma, brain cancer, ovarian cancer, neuroblastoma, lung cancer, colorectal cancer), benign neoplasms, diseases associated with angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of a kinase, such as a cyclin-dependent kinase (CDK) (e.g., CDK7, CDK12, or CDK13), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject. |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/561729 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Heterocyclic Compounds C07D 473/16 (20130101) Original (OR) Class C07D 473/34 (20130101) C07D 487/04 (20130101) Peptides C07K 14/4738 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550149 | Evans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Salk Institute for Biological Studies (La Jolla, California) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Ronald M. Evans (La Jolla, California); Michael Downes (La Jolla, California) |
| ABSTRACT | Provided herein are deuterated compounds and compositions useful in increasing PPARδ activity. The compounds have a formula where L5 comprises at least one deuterium. Exemplary species include The compounds and compositions provided herein are useful for the treatment of PPARδ related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases). |
| FILED | Thursday, June 28, 2018 |
| APPL NO | 16/022578 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/73 (20130101) C07C 233/75 (20130101) C07C 233/87 (20130101) C07C 235/42 (20130101) C07C 235/48 (20130101) C07C 235/84 (20130101) C07C 237/32 (20130101) C07C 255/57 (20130101) C07C 259/06 (20130101) C07C 317/44 (20130101) C07C 2601/02 (20170501) C07C 2601/08 (20170501) Heterocyclic Compounds C07D 205/04 (20130101) C07D 209/34 (20130101) C07D 213/40 (20130101) C07D 213/56 (20130101) C07D 213/64 (20130101) C07D 231/12 (20130101) C07D 271/12 (20130101) C07D 295/13 (20130101) C07D 295/155 (20130101) C07D 305/06 (20130101) C07D 307/54 (20130101) C07D 307/68 (20130101) C07D 307/81 (20130101) C07D 307/83 (20130101) C07D 309/04 (20130101) C07D 309/06 (20130101) C07D 333/24 (20130101) C07D 333/38 (20130101) C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 405/04 (20130101) C07D 405/10 (20130101) C07D 405/12 (20130101) C07D 407/12 (20130101) C07D 409/12 (20130101) C07D 413/04 (20130101) C07D 413/12 (20130101) C07D 417/04 (20130101) C07D 417/10 (20130101) C07D 417/12 (20130101) Peptides C07K 5/06026 (20130101) C07K 5/06034 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550151 | Sessa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | William C. Sessa (Madison, Connecticut); Frank J. Giordano (Madison, Connecticut) |
| ABSTRACT | An isolated transport peptide, which crosses the cell membrane of a cell and/or binds to a target cell is described. The transport peptide can be incorporated into a transport construct in which the transport peptide is linked to a cargo moiety to be delivered into a cell. Also described herein is a method of delivering a transport construct into and/or to a cell. |
| FILED | Friday, March 02, 2018 |
| APPL NO | 15/910519 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/645 (20170801) Peptides C07K 7/06 (20130101) Original (OR) Class C07K 14/4702 (20130101) C07K 14/4703 (20130101) C07K 2319/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550163 | Cai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Hua Cai (Los Angeles, California); Qiang Li (Los Angeles, California) |
| ABSTRACT | Disclosed herein are peptide fragments derived from netrin-1 and compositions thereof and methods of using thereof. In some embodiments, the present invention provides a peptide that is 8-65 amino acid residues long and has a core sequence having Formula I as follows: CX(1-2)CX(3-4)TX(0-1)G, wherein X is any amino acid residue. In some embodiments, the present invention provides a composition comprising one or more peptides of the present invention which have a core sequence according to Formula I, Formula IA, or Formula IB. CX(1-2)CX(3-4)TX(0-1)g (I) |
| FILED | Monday, March 30, 2015 |
| APPL NO | 15/300071 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/435 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550164 | Schlom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Jeffrey Schlom (Potomac, Maryland); Claudia M. Palena (Potomac, Maryland) |
| ABSTRACT | The invention provides Brachyury deletion mutant polypeptides, nucleic acids encoding the polypeptides, non-yeast vectors comprising the nucleic acids, non-yeast cells, and methods of use. |
| FILED | Wednesday, August 03, 2016 |
| APPL NO | 15/749214 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 38/193 (20130101) A61K 38/1709 (20130101) A61K 39/0011 (20130101) A61K 39/00117 (20180801) A61K 39/001152 (20180801) A61K 39/001182 (20180801) A61K 45/06 (20130101) A61K 2039/70 (20130101) A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4702 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/10043 (20130101) Technologies for Adaptation to Climate Change Y02A 50/466 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550169 | Teitelbaum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Steven Teitelbaum (St. Louis, Missouri); Daved Fremont (St. Louis, Missouri); Julia T. Warren (St. Louis, Missouri); Christopher Nelson (St. Louis, Missouri) |
| ABSTRACT | Methods for constructing efficient inhibitors of target TNF superfamily receptors, single chain target TNF superfamily ligands that inhibit of target TNF superfamily receptors while failing to engage or inhibit non-target TNF superfamily receptors, and methods of their use to treat diseases are provided. Single chain RANKL, TNF, and TRAIL ligands that effectively inhibit their target receptors while failing to inhibit non-target TNF superfamily receptors are also provided. |
| FILED | Monday, February 12, 2018 |
| APPL NO | 15/894502 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/70575 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/02 (20130101) C07K 2319/21 (20130101) C07K 2319/23 (20130101) C07K 2319/30 (20130101) C07K 2319/50 (20130101) C07K 2319/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550172 | Lucas |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Alexandra Rose Lucas (Gainesville, Florida) |
| ABSTRACT | Disclosed here are peptides derived from a serpin reactive center loop that have anti¬inflammatory, anti-atherogenic and anti-sepsis activity. Compositions containing such serpin-derived peptides are therefore useful in the treatment of transplant vascular disease and also for the treatment of hemorrhagic viral infections as well as lethal viral, fungal or bacterial sepsis in patients. |
| FILED | Friday, March 18, 2016 |
| APPL NO | 15/559867 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/00 (20130101) A61K 38/07 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/55 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) A61P 31/22 (20180101) Peptides C07K 5/1019 (20130101) C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/8121 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550176 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Roger Williams Hospital (Providence, Rhode Island) |
| ASSIGNEE(S) | ROGER WILLIAMS MEDICAL CENTER (Providence, Rhode Island) |
| INVENTOR(S) | Wen Yang (Sharon, Massachusetts); Richard P. Junghans (Boston, Massachusetts); Anthony J. Bais (Providence, Rhode Island) |
| ABSTRACT | The present invention relates to compositions and methods for creation of vector nucleic acid sequences (e.g., retroviral nucleic acid sequences) that comprise two or more exogenous nucleic acid sequences that encode highly homologous (e.g., identical) polypeptide sequences, yet wherein at least one of the exogenous nucleic acid sequences has been mutated using degenerate codons for purpose of reducing homology between the two or more exogenous nucleic acid sequences while maintaining the encoded polypeptide sequence. Preferred nucleic acid sequences include those encoding multi-chimeric immune receptor (CIR) genes. Specific nucleic acid sequences of such CIR genes are also disclosed. |
| FILED | Friday, December 04, 2015 |
| APPL NO | 14/960236 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 38/00 (20130101) A61K 48/00 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 16/40 (20130101) C07K 16/084 (20130101) C07K 2317/622 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2740/10032 (20130101) C12N 2740/10052 (20130101) C12N 2740/13043 (20130101) C12N 2740/13045 (20130101) C12N 2810/855 (20130101) C12N 2810/859 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550179 | Orentas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lentigen Technology Inc. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Lentigen Technology Inc. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Rimas J. Orentas (Washington, District of Columbia); Dina Schneider (Potomac, Maryland); Boro Dropulic (Gaithersburg, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland) |
| ABSTRACT | Chimeric antigen receptors containing mesothelin antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed. |
| FILED | Friday, January 18, 2019 |
| APPL NO | 16/252158 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 2317/21 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 15/09 (20130101) C12N 15/10 (20130101) C12N 15/62 (20130101) C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550195 | Liu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bin Liu (San Francisco, California) |
| ABSTRACT | Methods are provided for identifying and selecting antibodies that are internalized into cells via the macropinocytosis pathway. Additionally antibodies that are internalized via this pathway are provided as well as immunoconjugates comprising such antibodies. |
| FILED | Thursday, July 09, 2015 |
| APPL NO | 15/321684 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 49/00 (20130101) Peptides C07K 16/005 (20130101) C07K 16/30 (20130101) Original (OR) Class C07K 16/3069 (20130101) C07K 2317/21 (20130101) C07K 2317/32 (20130101) C07K 2317/73 (20130101) C07K 2317/77 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550201 | Peterson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BioVentures, LLC (Little Rock, Arkansas); Eric C. Peterson (Little Rock, Arkansas); Nisha Nanaware-Kharade (Little Rock, Arkansas); Guillermo Gonzalez, III (Little Rock, Arkansas) |
| ASSIGNEE(S) | BioVentures, LLC (Little Rock, Arkansas) |
| INVENTOR(S) | Eric C. Peterson (Little Rock, Arkansas); Nisha Nanaware-Kharade (Little Rock, Arkansas); Guillermo Gonzalez, III (Little Rock, Arkansas) |
| ABSTRACT | The present invention generally relates to an antibody composition including antibodies conjugated to nanoparticles. The antibody composition may be used in methods to treat drug use, drug addiction, and effects of drug use. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/775227 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/44 (20130101) Original (OR) Class C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550365 | Biggs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Manus J. P. Biggs (Galway, Ireland); Ryan Cooper (Oak Ridge, Tennessee); Jinyu Liao (New York, New York); Teresa Anne Fazio (Poughkeepsie, New York); Carl Fredrik Oskar Dahlberg (Stockholm, Sweden); Jeffrey William Kysar (New York, New York); Samuel Jonas Wind (White Plains, New York) |
| ABSTRACT | An elastomeric substrate comprises a surface with regions of heterogeneous rigidity, wherein the regions are formed by exposing the elastomeric substrate to an energy source to form the regions such that the regions include a rigidity pattern comprising spots. |
| FILED | Monday, April 10, 2017 |
| APPL NO | 15/483754 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) Original (OR) Class C12N 5/0663 (20130101) C12N 2533/30 (20130101) C12N 2535/00 (20130101) C12N 2535/10 (20130101) C12N 2537/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550372 | Konermann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); University of Tokyo (Tokyo, Japan); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); University of Tokyo (Tokyo, Japan); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Silvana Konermann (Zurich, Switzerland); Alexandro Trevino (Stanford, California); Mark Brigham (Somerville, Massachusetts); Fei Ran (Boston, Massachusetts); Patrick Hsu (San Diego, California); Chie-yu Lin (Boston, Massachusetts); Osamu Nureki (Kanagawa, Japan); Hiroshi Nishimasu (Tokyo, Japan); Ryuichiro Ishitani (Tokyo, Japan); Feng Zhang (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are structural information on the Cas protein of the CRISPR-Cas system, use of this information in generating modified components of the CRISPR complex, vectors and vector systems which encode one or more components or modified components of a CRISPR complex, as well as methods for the design and use of such vectors and components. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for utilizing the CRISPR-Cas system. In particular the present invention comprehends optimized functional CRISPR-Cas enzyme systems. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/179912 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 15/902 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550379 | Lin et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Michael Z. Lin (Stanford, California); Hokyung Chung (Mountain View, California); Conor Jacobs (Stanford, California) |
| ABSTRACT | Engineered fusion proteins comprising a self-excising degron for controlling protein production are disclosed. In particular, the inventors have constructed fusion proteins comprising a degron connected to a protein of interest through a cleavable linker comprising a hepatitis C virus (HCV) protease site. The degron can be removed from the protein of interest by a czs-encoded HCV protease such that the protein of interest can be produced with minimal structural modification. Clinically available HCV protease inhibitors can be used to block protease cleavage such that the degron is retained after inhibitor addition on subsequently synthesized protein copies. The degron when attached causes rapid degradation of the linked protein. Such fusions of a degron to a protein of interest will be especially useful when control over protein production with minimal structural modification is desired. |
| FILED | Tuesday, June 28, 2016 |
| APPL NO | 15/737712 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 2319/50 (20130101) C07K 2319/95 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/506 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2760/18443 (20130101) Enzymes C12Y 304/21098 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550388 | Monje-Deisseroth et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Michelle Monje-Deisseroth (Stanford, California); Elizabeth Qin (Palo Alto, California) |
| ABSTRACT | Compositions and methods for treatment of glioma are disclosed. In particular, the invention relates to methods of treating glioma by inhibiting pleiotrophin signaling to limit high-grade glioma invasion. |
| FILED | Wednesday, August 15, 2018 |
| APPL NO | 15/998437 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/713 (20130101) A61K 31/4439 (20130101) A61K 31/5377 (20130101) A61K 31/7105 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/14 (20130101) C12N 2310/122 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550395 | Xiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yi Xiao (Miami, Florida); Haixiang Yu (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Yi Xiao (Miami, Florida); Haixiang Yu (Miami, Florida) |
| ABSTRACT | The subject invention provides methods, assays and products for detecting small-molecules in a sample, in particular, in both clinical and field settings. The method for detecting a small-molecule target in a sample comprises providing a sample, contacting the sample with an aptamer-based sensor selective for the small-molecule target, and sensitively and rapidly detecting the small-molecule target in the sample. Specifically, the method utilizes EATR-amplified small-molecule sensors based on cooperative binding split aptamers (CBSAs). |
| FILED | Friday, April 06, 2018 |
| APPL NO | 15/947315 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/946 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550405 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Chengwen Li (Chapel Hill, North Carolina); Richard Jude Samulski (Hillsborough, North Carolina) |
| ABSTRACT | The present invention provides a polyploid adeno-associated virus (AAV) capsid, wherein the capsid comprises capsid protein VP1, wherein said capsid protein VP1 is from one or more than one first AAV serotype, wherein said capsid protein VP2 is from one or more than one first AAV serotype and capsid protein VP3, wherein said capsid protein VP3 is from one or more than one second AAV serotype and wherein at least one of said first AAV serotype is different from at least one of said second AAV serotype and is different from at least one of said third AAV serotype, in any combination. |
| FILED | Tuesday, July 31, 2018 |
| APPL NO | 16/051110 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/00 (20180101) Peptides C07K 2317/24 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8645 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550415 | Travis |
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| FUNDED BY |
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| APPLICANT(S) | Alexander Travis (Ithaca, New York) |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Alexander Travis (Ithaca, New York) |
| ABSTRACT | The present invention relates to a system for production of ATP. This system is comprised of a support and one or more enzymes coupled to that support which are capable of collectively producing ATP from glucose or fructose metabolism. The present invention is additionally directed to a device, which includes the system, and to a method for carrying out a reaction involving the conversion of ATP to ADP using the system. |
| FILED | Thursday, October 16, 2008 |
| APPL NO | 12/738367 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550422 | Gee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Life Technologies Corporation (Carlsbad, California) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Life Technologies Corporation (Carlsbad, California) |
| INVENTOR(S) | Kyle R. Gee (Springfield, Oregon); Brian Agnew (Eugene, Oregon); Adrian Salic (Cambridge, Massachusetts); Timothy J. Mitchison (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates to methods for the labeling of nucleic acid polymers in vitro and in vivo. Certain methods are provided that include a [3+2] cycloaddition between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent attached to a label. Other methods are provided that include a Staudinger ligation between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent comprising a substituted triarylphosphine attached to a label. Such methods do not require fixation and denaturation and therefore can be applied to the labeling of nucleic acid polymers in living cells and in organisms. Also provided are methods for measuring cellular proliferation. In these methods, the amount of label incorporated into the DNA is measured as an indication of cellular proliferation. The methods of the invention can be used in a wide variety of applications including clinical diagnosis of diseases and disorders in which cellular proliferation is involved, toxicity assays, and as a tool for the study of chromosomes' ultrastructures. |
| FILED | Monday, October 24, 2016 |
| APPL NO | 15/332304 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/68 (20130101) C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6841 (20130101) C12Q 1/6841 (20130101) C12Q 2525/101 (20130101) C12Q 2563/107 (20130101) C12Q 2563/107 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550433 | Ridker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Celera Corporation (Alameda, California) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Celera Corporation (Alameda, California) |
| INVENTOR(S) | Paul M. Ridker (Chestnut Hill, Massachusetts); Daniel Chasman (Cambridge, Massachusetts); Dov Shiffman (Palo Alto, California) |
| ABSTRACT | This invention relates to nucleotide polymorphisms in the human Apo(a) gene and to the use of Apo(a) nucleotide polymorphisms in identifying whether a human subject will respond or not to treatment with acetylsalicylic acid. |
| FILED | Monday, April 03, 2017 |
| APPL NO | 15/477206 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/616 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/172 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 2333/775 (20130101) G01N 2500/04 (20130101) G01N 2800/32 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550437 | Donskey et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Curtis Donskey (Cleveland, Ohio); Michelle Nerandzic (Cleveland, Ohio); Jennifer Cadnum (Cleveland, Ohio) |
| ABSTRACT | A culture medium for culturing Clostridium difficile under aerobic culture conditions, the medium includes a nutrient medium that promotes growth of Clostridium difficile and amounts of thioglycolic and L-cystine effective to consume oxygen in the culture medium and facilitate growth of Clostridium difficile. |
| FILED | Monday, June 01, 2015 |
| APPL NO | 15/315240 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/523 (20130101) G01N 33/6893 (20130101) G01N 2333/902 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550441 | Petropoulos |
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| FUNDED BY |
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| APPLICANT(S) | MONOGRAM BIOSCIENCES, INC. (South San Francisco, California) |
| ASSIGNEE(S) | Monogram BioSciences, Inc. (South San Francisco, California) |
| INVENTOR(S) | Christos J. Petropoulos (Half Moon Bay, California) |
| ABSTRACT | The invention provides a method for determining whether a human immunodeficiency virus is resistance to a viral entry inhibitor. The methods are particularly useful for determining resistance to inhibitors that act by a non-competitive mechanism. In certain aspects, the methods comprise determining whether an HIV population is resistant to an HIV entry inhibitor, comprising determining a log-sigmoid inhibition curve comprising data points for entry of the HIV population in the presence of varying concentrations of the HIV entry inhibitor, wherein if the entry of the HIV population cannot be completely inhibited by the HIV entry inhibitor, the HIV population is resistant to the HIV entry inhibitor. |
| FILED | Monday, December 09, 2013 |
| APPL NO | 14/100467 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550494 | Savoy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Steve M. Savoy (Austin, Texas); Daniel R. Mitchell (Austin, Texas); Jeremy J. John (Austin, Texas); George L. Murphy (Austin, Texas) |
| ASSIGNEE(S) | NANOHMICS, INC. (Austin, Texas) |
| INVENTOR(S) | Steve M. Savoy (Austin, Texas); Daniel R. Mitchell (Austin, Texas); Jeremy J. John (Austin, Texas); George L. Murphy (Austin, Texas) |
| ABSTRACT | Analyte filter arrays and methods for making an analyte filter array are provided. The arrays are formed using a dispersion of filter particles having selected moieties attached to the surface of the particles and a microarray having complementary moieties formed in an array on a substrate, such that each filter particle is attached to a selected region of the microarray. The moiety on the substrate may be RNA or DNA or other molecule. The substrate may be a surface of a detector array, a membrane that may be placed in registration with the detector array or a stamp used to transfer the filter array to a detector array. |
| FILED | Monday, October 23, 2017 |
| APPL NO | 15/791403 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/00382 (20130101) B01J 2219/00576 (20130101) B01J 2219/00637 (20130101) B01J 2219/00648 (20130101) B01J 2219/00722 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551381 | Bosch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America as Represented by the Secretary of the Department of Health and Human Services (Silver Springs, Maryland) |
| INVENTOR(S) | Irene Bosch (Brookline, Massachusetts); Kimberly Hamad-Schifferli (Somerville, Massachusetts); Jose Gomez-Marquez (Boston, Massachusetts); Helena de Puig (Cambridge, Massachusetts); Lee Gehrke (Cotuit, Massachusetts) |
| ABSTRACT | The present invention provides matched antibody pairs for the specific detection of one or more of the four dengue virus serotypes in a biological sample that may contain one or more of such dengue virus serotypes. Each matched antibody pair is capable of detecting not more than one serotype of dengue virus NS1 protein that may be present in the sample and will not cross react with other serotypes that may be present in the sample. Multiple matched pairs may be used to detect one or more dengue virus serotypes that may be present in a sample. Such matched pair antibodies, facilitate the development of confirmatory in vitro diagnostic tests such as sandwich immunoassays, that detect and distinguish the presence of one or more dengue virus serotypes in a biological sample, preferably a sample derived from human subject. The invention also provides kits comprising the matched antibody pairs of the invention and methods for using the kits for immunoassays for the specific detection of one or more serotypes of dengue virus in a patient population. The present invention also provides monoclonal antibodies specific for the NS1 protein of dengue virus and therapeutic compositions and methods for treating dengue virus infection. |
| FILED | Friday, February 10, 2017 |
| APPL NO | 15/429756 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 2317/34 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) Original (OR) Class G01N 2333/08 (20130101) G01N 2469/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551384 | Zheng |
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| FUNDED BY |
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| APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University Of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Steven Zheng (New Brunswick, New Jersey) |
| ABSTRACT | Certain embodiments of the invention provide a method of detecting the presence of a biomarker associated with resistance to an mTOR kinase inhibitor in a subject, comprising determining the presence of the biomarker in a physiological sample from the subject, wherein the sample comprises a nucleic acid. |
| FILED | Friday, April 07, 2017 |
| APPL NO | 15/482340 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) A61K 31/495 (20130101) A61K 31/519 (20130101) A61K 31/4709 (20130101) A61K 31/4745 (20130101) A61K 31/5377 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 207/11 (20130101) C12Y 207/11011 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57415 (20130101) G01N 33/57419 (20130101) G01N 33/57423 (20130101) G01N 33/57484 (20130101) Original (OR) Class G01N 2333/912 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551393 | Thierer et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); CARNEGIE INSTITUTION OF WASHINGTON (Washington, District of Columbia) |
| ASSIGNEE(S) | CARNEGIE INSTITUTE OF WASHINGTON (Washington, District of Columbia); The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | James H. Thierer (Baltimore, Maryland); Steven A. Farber (Baltimore, Maryland) |
| ABSTRACT | We describe a high-throughput, phenotypic screening method for one or more modulator(s) of Apolipoprotein B (ApoB) in larval zebrafish. The modulator(s) may be enhancers or inhibitors of ApoB expression. This represents a remarkable opportunity to investigate drug targets in every cell and tissue type of a whole animal without bias, thus maximizing the likelihood of identifying viable pre-therapeutic leads for compounds or biologics in a subject (e.g., human). |
| FILED | Thursday, June 01, 2017 |
| APPL NO | 15/611780 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/461 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/09 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551450 | Halpern et al. |
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| FUNDED BY |
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| APPLICANT(S) | Howard Halpern (Chicago, Illinois); Subramanian V. Sundramoorthy (Chicago, Illinois); Boris Epel (Chicago, Illinois) |
| ASSIGNEE(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Howard Halpern (Chicago, Illinois); Subramanian V. Sundramoorthy (Chicago, Illinois); Boris Epel (Chicago, Illinois) |
| ABSTRACT | Techniques provide for passive Q switching in a bimodal resonator environment, where magnetic resonators are coupled for power transfer. A passive Q switch is responsive to a driving power from one magnetic resonator coupled to another magnetic resonator. After the driving power reaches a threshold, the passive Q switch shunts the receiving magnetic resonator, at least partially, to reduce the Q of that second resonator, which allows faster detection operation of the second resonator in some applications. The technique allows for fast Q switching in a bimodal resonator system, especially one having resonators having magnetic fields that are orthogonal to one another. |
| FILED | Thursday, June 14, 2012 |
| APPL NO | 14/128423 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/60 (20130101) G01R 33/343 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10552955 | Hu et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Chenxi Hu (New Haven, Connecticut); Dana Peters (New London, Connecticut) |
| ABSTRACT | The present invention provides novel methods of accurately and efficiently reconstructing parameter maps in MRI data. In certain embodiments, the methods have reduced data acquisition time or improved spatial resolution when compared to methods standard in the art. In other embodiments, the methods have reduced acquisition and reconstruction time when compared to other acceleration methods in the art in parametric mapping. In other embodiments, the methods are less susceptible to influence of eddy currents when compared to other acceleration methods in the art in parametric mapping. |
| FILED | Wednesday, April 04, 2018 |
| APPL NO | 15/945301 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 11/005 (20130101) G06T 11/006 (20130101) G06T 11/008 (20130101) G06T 15/08 (20130101) G06T 2207/30008 (20130101) G06T 2207/30016 (20130101) G06T 2207/30048 (20130101) G06T 2207/30056 (20130101) G06T 2207/30068 (20130101) G06T 2207/30081 (20130101) G06T 2207/30084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10552969 | Simpson et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Amber Lea Simpson (New York, New York); Richard Kinh Gian Do (New York, New York) |
| ABSTRACT | An exemplary system, method and computer-accessible medium for determining the pixel variation of a tissue(s) in an image(s) can be provided, which can include, for example, receiving first imaging information related to the image(s), segmenting a region(s) of interest from the image(s), generating second imaging information by subtracting a structure(s) from the region(s) of interest, and determining the pixel variation based on the second imaging information. The tissue(s) can include a liver and/or a pancreas. A treatment characteristic(s) can be determined based on the pixel variation, which can include (i) a sufficiency of the tissue(s), (ii) a response to chemotherapy by the tissue(s), (iii) a recurrence of cancer in the tissue(s), or (iv) a measure of a genomic expression of the tissue(s). |
| FILED | Thursday, May 26, 2016 |
| APPL NO | 15/577101 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/50 (20130101) A61B 6/54 (20130101) A61B 6/5217 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/46 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 7/0014 (20130101) G06T 7/40 (20130101) G06T 7/45 (20170101) Original (OR) Class G06T 7/155 (20170101) G06T 7/194 (20170101) G06T 2207/10072 (20130101) G06T 2207/10081 (20130101) G06T 2207/20224 (20130101) G06T 2207/30004 (20130101) G06T 2207/30056 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553199 | Guenther et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Frank Harold Guenther (Boston, Massachusetts); Alfonso Nieto-Castanon (Ciudad de Buenos Aires, Argentina) |
| ABSTRACT | A method of providing real-time speech synthesis based on user input includes presenting a graphical user interface having a low-dimensional representation of a multi-dimensional phoneme space, a first dimension representing degree of vocal tract constriction and voicing, a second dimension representing location in a vocal tract. One example employs a disk-shaped layout. User input is received via the interface and translated into a sequence of phonemes that are rendered on an audio output device. Additionally, a synthesis method includes maintaining a library of prerecorded samples of diphones organized into diphone groups, continually receiving a time-stamped sequence of phonemes to be synthesized, and selecting a sequence of diphone groups with their time stamps. A best diphone within each group is identified and placed into a production buffer from which diphones are rendered according to their time stamps. |
| FILED | Friday, May 20, 2016 |
| APPL NO | 15/570889 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 3/048 (20130101) G06F 3/0482 (20130101) G06F 3/04842 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 13/04 (20130101) Original (OR) Class G10L 13/06 (20130101) G10L 13/08 (20130101) G10L 13/027 (20130101) G10L 15/00 (20130101) G10L 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE47838 | Wall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| INVENTOR(S) | Jonathan S. Wall (Knoxville, Tennessee); Timothy E. Sparer (Knoxville, Tennessee); Stephen J. Kennel (Knoxville, Tennessee) |
| ABSTRACT | Disclosed are methods of treating and/or inhibiting a viral infection in a subject. The methods include administering a therapeutically effective amount of heparin-binding peptide. Also disclosed herein are methods for blocking viral binding to a cell. Further disclosed are anti-viral compositions for administration to a subject infected with a virus. Administration of the anti-viral composition inhibits viral infection of the subject. |
| FILED | Tuesday, January 30, 2018 |
| APPL NO | 15/883982 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 14/001 (20130101) C07K 14/035 (20130101) C07K 14/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10548519 | Arias et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ana Claudia Arias (Berkeley, California); Claire Lochner (Berkeley, California); Adrien Pierre (Berkeley, California); Yasser Khan (Berkeley, California) |
| ABSTRACT | Pulse oximeter devices include a first light emitting element that emits red light, a second light emitting element that emits green light or IR light; and a sensor element that detects red and green (or IR) light and that outputs signals representing detected red and green (or IR) light. The pulse oximeter device further includes a flexible substrate, wherein the first light emitting element, the second light emitting element and the sensor element are formed on the flexible substrate. The sensor element is configured to detect the emitted red and green light transmitted through tissue containing blood, and in certain aspects, the sensor element is configured to detect the emitted red and green (or IR) light reflected by tissue containing blood. A signal processing element (e.g., a processor) receives and processes the signals representing detected red and green (or IR) light output by the sensor element to produce signals representing blood oxygenation content. |
| FILED | Tuesday, January 24, 2017 |
| APPL NO | 15/414397 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/024 (20130101) A61B 5/0205 (20130101) A61B 5/6815 (20130101) A61B 5/6826 (20130101) A61B 5/14552 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548944 | Jaynes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Riptide Bioscience, Inc. (Vallejo, California) |
| ASSIGNEE(S) | Riptide Bioscience, Inc. (Vallejo, California) |
| INVENTOR(S) | Jesse Jaynes (Auburn, Alabama); L. Edward Clemens (Sacramento, California); Henry Willfred Lopez (Napa, California); George R. Martin (Rockville, Maryland); Kathryn Woodburn (Saratoga, California) |
| ABSTRACT | Aspects of the present invention relate to peptides having antimicrobial activity. In certain aspects, the invention relates to peptides having potent antimicrobial activity, broad-spectrum antimicrobial activity, and/or the ability to kill otherwise antibiotic-resistant microbes, or microbes protected by biofilms. |
| FILED | Friday, October 19, 2018 |
| APPL NO | 16/165727 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0053 (20130101) A61K 9/0073 (20130101) A61K 38/10 (20130101) Original (OR) Class A61K 38/16 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 31/10 (20180101) Peptides C07K 7/08 (20130101) C07K 14/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548946 | Golden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Army, on behalf of the United States (Fort Detrick, Maryland) |
| ASSIGNEE(S) | The government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Joseph Golden (Hagerstown, Maryland); Jay Hooper (New Market, Maryland) |
| ABSTRACT | The inventions describe here cover therapeutic compositions, and methods of use, for neutralizing Type I interferons in a mammal. The compositions contain a soluble Orthopoxvirus IFN-binding protein that is modified to remove the cell-binding region, and that specifically binds to Type I IFNs, and a pharmaceutically acceptable carrier or excipient. Another variation of the invention entails a novel IFN-binding protein that is modified to remove the cell-binding region and the signal sequence. |
| FILED | Friday, December 01, 2017 |
| APPL NO | 15/828582 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/162 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548948 | Millenbaugh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nancy Millenbaugh (San Antonio, Texas); Jeremy Wesley Gleaton (Cleveland, Ohio); Dickson Kiprono Kirui (San Antonio, Texas) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Nancy Millenbaugh (San Antonio, Texas); Jeremy Wesley Gleaton (Cleveland, Ohio); Dickson Kiprono Kirui (San Antonio, Texas) |
| ABSTRACT | Antifungal pharmaceutical compositions, dosage forms, and methods of use thereof are disclosed. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 15/906863 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1767 (20130101) Original (OR) Class A61K 45/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/44 (20130101) A61L 2300/252 (20130101) A61L 2300/404 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548959 | Khan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambirdge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Omar F. Khan (Cambridge, Massachusetts); Jasdave S. Chahal (Arlington, Massachusetts); Daniel G. Anderson (Framington, Massachusetts); Hidde Ploegh (Brookline, Massachusetts); Robert S. Langer (Newton, Massachusetts); Tyler E. Jacks (Newton, Massachusetts); David A. Canner (Cambridge, Massachusetts) |
| ABSTRACT | Compositions and methods for modified dendrimer nanoparticle (“MDNP”) delivery of therapeutic, prophylactic and/or diagnostic agent such as large repRNA molecules to the cells of a subject have been developed. MDNPs efficiently drive proliferation of antigen-specific T cells against intracellular antigen, and potentiate antigen-specific antibody responses. MDNPs can be multiplexed to deliver two or more different repRNAs to modify expression kinetics of encoded antigens and to simultaneous deliver repRNAs and mRNAs including the same UTR elements that promote expression of encoded antigens. |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/274954 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 39/0012 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549122 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vision RT Limited (London, United Kingdom) |
| ASSIGNEE(S) | VISION RT LIMITED (London, United Kingdom) |
| INVENTOR(S) | Chieh C. Cheng (Redlands, California); David A. Lesyna (Redlands, California); Michael F. Moyers (Colton, California) |
| ABSTRACT | Apparatus and methods for therapy delivery are disclosed. In one embodiment, a therapy delivery system includes a plurality of movable components including a radiation therapy nozzle and a patient pod for holding a patient, a patient registration module for determining a desired position of at least one of the plurality of movable components, and a motion control module for coordinating the movement of the least one of the plurality of movable components from a current position to the desired position. The motion control module includes a path planning module for simulating at least one projected trajectory of movement of the least one of the plurality of moveable components from the current position to the desired position. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 15/995987 |
| ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/0442 (20130101) A61B 6/547 (20130101) A61B 6/4092 (20130101) A61B 2090/3937 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/107 (20130101) Original (OR) Class A61N 5/1037 (20130101) A61N 5/1049 (20130101) A61N 5/1067 (20130101) A61N 5/1069 (20130101) A61N 5/1078 (20130101) A61N 2005/105 (20130101) A61N 2005/1059 (20130101) A61N 2005/1061 (20130101) A61N 2005/1062 (20130101) A61N 2005/1087 (20130101) A61N 2005/1097 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/1666 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) G05B 2219/45117 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549259 | Sengupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Louise C. Sengupta (Ellicott City, Maryland); Pierre-Alain S. Auroux (Rockville, Maryland); Christopher S. Badorrek (Hagerstown, Maryland); Michael J. Bowers, II (Sykesville, Maryland); Myeongseob Kim (Ellicott City, Maryland); John E. King (Ellicott City, Maryland); Tadd C. Kippeny (Pasadena, Maryland); Laura A. Swafford (Baltimore, Maryland) |
| ABSTRACT | In the method for scrubbing a chemical from a medium, wherein the improvement comprises the steps of using a carbide derived carbon to adsorb the chemical which may later be released by heating. The carbide derived carbon may be a powder, a fiber, a solid foam, a mesh, or other solid form. The carbide derived carbon can adsorb a chemical in the gaseous, liquid, particulate, or aerosol phase. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 15/690358 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 53/0438 (20130101) B01D 2253/102 (20130101) B01D 2253/106 (20130101) B01D 2257/40 (20130101) B01D 2257/204 (20130101) B01D 2257/302 (20130101) B01D 2257/304 (20130101) B01D 2257/406 (20130101) B01D 2257/704 (20130101) B01D 2257/708 (20130101) B01D 2257/2025 (20130101) B01D 2257/2064 (20130101) B01D 2257/7022 (20130101) B01D 2257/7027 (20130101) B01D 2258/06 (20130101) B01D 2259/4508 (20130101) B01D 2259/4541 (20130101) B01D 2259/4566 (20130101) B01D 2259/40096 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/20 (20130101) Original (OR) Class B01J 20/3483 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/318 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550003 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Xiaolong Liu (Evanston, Illinois) |
| ABSTRACT | Articles comprising a boron allotrope and an organic compound having a lateral interface one with the other, together with method(s) of preparation of such articles. |
| FILED | Thursday, February 08, 2018 |
| APPL NO | 15/892124 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/04 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/20 (20130101) C01P 2002/60 (20130101) C01P 2004/90 (20130101) C01P 2006/40 (20130101) C01P 2006/90 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/04 (20130101) C23C 16/22 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0011 (20130101) H01L 51/0053 (20130101) H01L 51/0096 (20130101) H01L 2251/301 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550008 | MacDougall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | United States of American, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Craig A MacDougall (Norco, California); Dylan Switzer (Riverside, California); Aaron Wiest (Norco, California) |
| ABSTRACT | A low energy fluid purification system and method of implementation including some embodiments having a vacuum-rated first chamber placed in or near a body of water with higher temperature near the surface and lower temperatures at greater depths. The vacuum-rated first chamber holds a quantity of non-potable water and a low pressure area less than or equal to the water's vapor pressure. Vaporization occurs when the higher temperature surface water is brought into contact with the low pressure area. A tubular vapor transport passage allows the vaporized water to pass to a lower temperature and lower pressure condensation chamber. The lower temperature condensation chamber is cooled by lower temperature water from a selected depth below the surface. As the temperature of the vapor lowers, the vapor will condense. This condensation is collected as a quantity of potable water. Additional embodiments and methods are also provided. |
| FILED | Saturday, May 07, 2016 |
| APPL NO | 15/149084 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 3/106 (20130101) B01D 5/0003 (20130101) B01D 5/006 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/06 (20130101) C02F 1/12 (20130101) C02F 1/043 (20130101) Original (OR) Class C02F 1/046 (20130101) C02F 2103/08 (20130101) C02F 2301/063 (20130101) C02F 2307/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550070 | Malkas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Linda H. Malkas (Duarte, California); David Horne (Altadena, California); Robert J. Hickey (Duarte, California); Long Gu (Duarte, California) |
| ABSTRACT | Described herein, inter alia, are compositions of PCNA modulators and methods for treating or preventing cancer. |
| FILED | Friday, September 16, 2016 |
| APPL NO | 15/760959 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/4409 (20130101) A61K 33/24 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Acyclic or Carbocyclic Compounds C07C 233/76 (20130101) Original (OR) Class Heterocyclic Compounds C07D 213/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550145 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Dongran Han (Brookline, Massachusetts); Cameron Myhrvold (Cambridge, Massachusetts); Peng Yin (Brookline, Massachusetts) |
| ABSTRACT | The present disclosure relates to nanostructures assembled from nucleic acid consisting of a single strand of DNA rationally-designed to self-assemble into a hairpin loop, helical domains, and locking domains. |
| FILED | Friday, March 04, 2016 |
| APPL NO | 15/556436 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 21/04 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Enzymes C12Y 207/00 (20130101) C12Y 301/11003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550271 | Haddad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright Patterson AFB, Ohio) |
| INVENTOR(S) | Timothy S. Haddad (Lancaster, California); Joseph M. Mabry (Lancaster, California); Sean Ramirez (Lancaster, California) |
| ABSTRACT | A method of forming a hydrophobic and oleophobic surface. The method including spin coating an F-POSS with 3,3-dichloro-1,1,1,2,2,-pentafluoropropane/1,3-dichloro-1,1,2,2,3-pentafluoropropane onto an inert surface. The F-POSS has a structure: Each Rf represents a nonreactive, fluorinated organic group, R1 represents a first monovalent organic group comprising at least two carbon atoms, and R2 represents hydrogen or a second monovalent organic group comprising at least two carbon atoms. The F-POSS with 3,3-dichloro-1,1,1,2,2,-pentafluoropropane/1,3-dichloro-1,1,2,2,3-pentafluoropropane are then dried on the inert surface. |
| FILED | Tuesday, September 19, 2017 |
| APPL NO | 15/708382 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 5/083 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/21 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/045 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/549 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1662 (20130101) Original (OR) Class C09D 7/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550272 | Aizenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Joanna Aizenberg (Boston, Massachusetts); Benjamin Hatton (Toronto, Canada); Donald Ingber (Boston, Massachusetts); Michael Super (Lexington, Massachusetts); Tak Sing Wong (State College, Pennsylvania) |
| ABSTRACT | A self-healing, scratch resistant slippery surface that is manufactured by wicking a chemically-inert, high-density liquid coating over a roughened solid surface featuring micro and nanoscale topographies is described. Such a slippery surface shows anti-wetting properties, as well as exhibits significant reduction of adhesion of a broad range of biological materials, including particles in suspension or solution. Specifically, the slippery surfaces can be applied to medical devices and equipment to effectively repel biological materials such as blood, and prevent, reduce, or delay coagulation and surface-mediated clot formation. Moreover, the slippery surfaces can be used to prevent fouling by microorganisms such as bacteria. |
| FILED | Tuesday, April 03, 2018 |
| APPL NO | 15/944619 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/24 (20130101) A61L 15/24 (20130101) A61L 15/34 (20130101) A61L 15/42 (20130101) A61L 15/46 (20130101) A61L 27/28 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/50 (20130101) A61L 33/064 (20130101) A61L 33/064 (20130101) A61L 33/0094 (20130101) A61L 2400/12 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 5/083 (20130101) Compositions of Macromolecular Compounds C08L 27/12 (20130101) C08L 27/12 (20130101) C08L 27/12 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1656 (20130101) C09D 5/1681 (20130101) C09D 5/1693 (20130101) Original (OR) Class Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/02 (20130101) F15D 1/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550303 | Trice et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Rodney Trice (West Lafayette, Indiana); Winnie Tan (West Lafayette, Indiana) |
| ABSTRACT | A hypersonic refractory material, including a refractory leading edge portion for a hypersonic vehicle and a high emissivity oxide coating adhered to the refractory leading edge portion. The high emissivity oxide coating is ZrB2 doped with a cation dopant material selected from the group including Sm, Tm, and mixtures thereof. The cation dopant material is present in a concentration of between 3 mole percent and 8 mole percent. |
| FILED | Monday, June 26, 2017 |
| APPL NO | 15/632506 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Aeroplanes; Helicopters B64C 30/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/58078 (20130101) C04B 35/62222 (20130101) C04B 2235/443 (20130101) C04B 2235/3224 (20130101) C04B 2235/3813 (20130101) C04B 2235/3826 (20130101) C04B 2235/9607 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) Original (OR) Class Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 19/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550330 | Yelvington et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mainstream Engineering Corporation (Rockledge, Florida) |
| ASSIGNEE(S) | Mainstream Engineering Corporation (Rockledge, Florida) |
| INVENTOR(S) | Paul E. Yelvington (Rockledge, Florida); Dustin J. Zastrow (Wausau, Wisconsin); Nicholas R. Schwartz (Rockledge, Florida) |
| ABSTRACT | An apparatus and method are described for high-yield fast pyrolysis of biomass feedstock to produce a liquid bio-oil product. A bubbling fluidized bed reactor is provided having an integrated, rapid quench apparatus for minimizing secondary cracking reactions that can otherwise lower the yield of bio-oil. A quench stream is provided inside the reactor to minimize the residence time that the product vapors spend at high temperature where cracking can occur. The quench stream is introduced downstream of the fluidized bed but still internal to the reactor. The fluidized bed medium is constrained to the bottom of the reactor and is not cooled by the quench stream. |
| FILED | Tuesday, October 24, 2017 |
| APPL NO | 15/791916 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/24 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550343 | Patel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nikhil Manubhai Patel (Grand Forks, North Dakota) |
| ASSIGNEE(S) | Nikhil Manubhai Patel (Grand Forks, North Dakota) |
| INVENTOR(S) | Nikhil Manubhai Patel (Grand Forks, North Dakota) |
| ABSTRACT | The present invention discloses a gasifier and/or a gasification process that provides a long, uniform temperature zone in the gasifier, regardless of the particle size, chemical composition, and moisture content of the fuel by sandwiching a reduction zones between two oxidation zones. The gasifier and/or gasification process has a char that is more energy-dense and almost devoid of moisture that affords for an additional (or char) oxidation zone with a temperature that is higher than a first oxidation zone which is closer to a evaporation and devolatilization zone. As such, the additional (or char) oxidation zone contributes to augmenting the reduction zone temperature, thereby providing a favorable dual impact in improving syngas composition and near-complete conversion of the tar. |
| FILED | Monday, May 28, 2018 |
| APPL NO | 15/990725 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/08 (20130101) Original (OR) Class C10J 3/22 (20130101) C10J 3/26 (20130101) C10J 3/723 (20130101) C10J 2300/092 (20130101) C10J 2300/093 (20130101) C10J 2300/0946 (20130101) C10J 2300/0956 (20130101) C10J 2300/0959 (20130101) C10J 2300/0976 (20130101) C10J 2300/1246 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 1/024 (20130101) C10K 1/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550388 | Monje-Deisseroth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Michelle Monje-Deisseroth (Stanford, California); Elizabeth Qin (Palo Alto, California) |
| ABSTRACT | Compositions and methods for treatment of glioma are disclosed. In particular, the invention relates to methods of treating glioma by inhibiting pleiotrophin signaling to limit high-grade glioma invasion. |
| FILED | Wednesday, August 15, 2018 |
| APPL NO | 15/998437 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/713 (20130101) A61K 31/4439 (20130101) A61K 31/5377 (20130101) A61K 31/7105 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/14 (20130101) C12N 2310/122 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550392 | Eberly |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jed O. Eberly (Vicksburg, Mississippi) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Jed O. Eberly (Vicksburg, Mississippi) |
| ABSTRACT | The present invention provides synthetic DNA aptamers that bind a target explosive to allow detection of that explosive. In various embodiments, the synthetic DNA aptamers may include one or more aptamers selected from the group consisting of SEQ ID 1-6. The various synthetic DNA aptamers are sensitive to different explosives. The synthetic DNA aptamers provide an inexpensive, in situ means for testing for explosive, which may be used for both soil and water samples. This testing may include an assay method using the synthetic DNA aptamers or a biosensor linked to the synthetic DNA aptamers. |
| FILED | Thursday, September 22, 2016 |
| APPL NO | 15/273592 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/16 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/227 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550423 | Gray |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IBIS BIOSCIENCES, INC. (Carlsbad, California) |
| ASSIGNEE(S) | IBIS BIOSCIENCES, INC. (Carlsbad, California) |
| INVENTOR(S) | Phillip N. Gray (Carlsbad, California) |
| ABSTRACT | Provided herein is technology relating to depositing and/or placing a macromolecule at a desired site for an assay and particularly, but not exclusively, to methods and systems for transporting a macromolecule such as a protein, a nucleic acid, or a protein:nucleic acid complex to an assay site, such as the bottom of a nanopore, a nanowell, or a zero mode waveguide. |
| FILED | Monday, October 30, 2017 |
| APPL NO | 15/797982 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2521/543 (20130101) C12Q 2522/101 (20130101) C12Q 2565/631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550431 | Rahme et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Laurence Rahme (Brookline, Massachusetts); Shuangchun Yan (Cambridge, Massachusetts); Yok-Ai Que (Pully, Switzerland); Amy Tsurumi (Boston, Massachusetts) |
| ABSTRACT | The technology described herein is directed to the diagnosis, prognosis, and treatment of infection, e.g. after burn injury. |
| FILED | Thursday, November 13, 2014 |
| APPL NO | 15/027067 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/26 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550494 | Savoy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Steve M. Savoy (Austin, Texas); Daniel R. Mitchell (Austin, Texas); Jeremy J. John (Austin, Texas); George L. Murphy (Austin, Texas) |
| ASSIGNEE(S) | NANOHMICS, INC. (Austin, Texas) |
| INVENTOR(S) | Steve M. Savoy (Austin, Texas); Daniel R. Mitchell (Austin, Texas); Jeremy J. John (Austin, Texas); George L. Murphy (Austin, Texas) |
| ABSTRACT | Analyte filter arrays and methods for making an analyte filter array are provided. The arrays are formed using a dispersion of filter particles having selected moieties attached to the surface of the particles and a microarray having complementary moieties formed in an array on a substrate, such that each filter particle is attached to a selected region of the microarray. The moiety on the substrate may be RNA or DNA or other molecule. The substrate may be a surface of a detector array, a membrane that may be placed in registration with the detector array or a stamp used to transfer the filter array to a detector array. |
| FILED | Monday, October 23, 2017 |
| APPL NO | 15/791403 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/00382 (20130101) B01J 2219/00576 (20130101) B01J 2219/00637 (20130101) B01J 2219/00648 (20130101) B01J 2219/00722 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550708 | Paulino et al. |
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| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Jose R. Paulino (Saco, Maine); Conway Chuong (Manchester, Connecticut); Joey Wong (Enfield, Connecticut); Christopher J. Peters (West Hartford, Connecticut); Ross Wilson (South Glastonbury, Connecticut) |
| ABSTRACT | Aspects of the disclosure are directed to a floating, non-contact seal comprising: a shoe, and at least three beams, each beam having a first axial end and a second axial end, where the first axial ends are coupled to the shoe and the second axial ends are coupled to a ring structure. Aspects of the disclosure are directed to an engine comprising: a first structure, a second structure configured to rotate relative to the first structure, and a floating, non-contact seal that interfaces the first structure and the second structure, where the seal includes: a shoe, and at least three beams, where each beam has a first axial end and a second axial end, where the first axial ends are coupled to the shoe and the second axial ends are coupled to a ring structure. |
| FILED | Wednesday, August 31, 2016 |
| APPL NO | 15/252942 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 11/025 (20130101) Original (OR) Class F01D 25/24 (20130101) Non-positive-displacement Pumps F04D 29/053 (20130101) F04D 29/083 (20130101) F04D 29/321 (20130101) F04D 29/522 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550860 | Perkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Alexander Douglas Perkins (Arlington, Massachusetts); Kevin Blankespoor (Arlington, Massachusetts); Alfred Anthony Rizzi (Waltham, Massachusetts) |
| ABSTRACT | In some applications, a piston of a hydraulic actuator may move at high speeds, and large undesired forces may be generated if the piston reaches an end-stop of the hydraulic actuator at a high speed. The undesired forces may, for example, cause mechanical damage in the hydraulic actuator. A controller may receive information indicative of the piston reaching a first position at a first threshold distance from the end-stop, and, in response, may modify a signal to a valve assembly controlling flow of hydraulic fluid to and from the hydraulic actuator. Further, the controller may receive information indicative of the piston reaching a second position at a second threshold distance closer to the end-stop of the hydraulic actuator, and, in response, the controller may further modify the signal to the valve assembly so as to apply a force on the piston in a away from the end-stop. |
| FILED | Friday, December 09, 2016 |
| APPL NO | 15/373626 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 9/09 (20130101) F15B 11/048 (20130101) F15B 13/021 (20130101) Original (OR) Class F15B 15/28 (20130101) F15B 15/2815 (20130101) F15B 21/08 (20130101) F15B 2211/665 (20130101) F15B 2211/755 (20130101) F15B 2211/6336 (20130101) F15B 2211/6654 (20130101) F15B 2211/6656 (20130101) F15B 2211/6658 (20130101) F15B 2211/7053 (20130101) F15B 2211/7653 (20130101) F15B 2211/8606 (20130101) F15B 2211/30575 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551131 | Lockwood et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Windsor Locks, Connecticut) |
| INVENTOR(S) | William T. Lockwood (Windsor Locks, Connecticut); Matthew William Miller (Enfield, Connecticut); Luke J. Mayo (Coventry, Connecticut) |
| ABSTRACT | A method for manufacturing a heat exchanger includes stacking a plurality of parting sheets, a plurality of lengthwise closure bars, and a plurality of widthwise closure bars to form a rectangular first heat exchanger section. The first heat exchanger section includes at least one widthwise passage extending between a pair of the widthwise closure bars and at least one lengthwise passage extending between a pair of the lengthwise closure bars. The method also includes brazing the rectangular first heat exchanger section together and cutting a first side and a second side of the rectangular first heat exchanger section to give the first heat exchanger section a tapered-trapezoid profile. The method further includes brazing an end of a second heat exchanger section to the first or second side of the first heat exchanger section. |
| FILED | Monday, January 08, 2018 |
| APPL NO | 15/864760 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/0012 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/0246 (20130101) F28D 1/05366 (20130101) F28D 7/005 (20130101) F28D 9/0025 (20130101) F28D 9/0062 (20130101) F28D 2021/0021 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/025 (20130101) Original (OR) Class F28F 9/26 (20130101) F28F 2210/10 (20130101) F28F 2240/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551162 | Floyd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| INVENTOR(S) | Brian Floyd (Raleigh, North Carolina); Vikas Chauhan (Raleigh, North Carolina); Kevin Greene (Raleigh, North Carolina) |
| ABSTRACT | Embodiments of a code modulated phased-array interferometer are described. In one embodiment, a code modulated phased-array interferometer includes a phased array having a plurality of receiver elements that receive a plurality of received signals. A code multiplexer multiplexes each of the plurality of received signals to generate a plurality of code multiplexed signals, and a combiner combines the plurality of code multiplexed signals into a combined signal. After other processing for signal reception, a code demultiplexer demultiplexes the combined baseband signal, and a complex correlator correlates unique pairs of baseband signals to generate a plurality of visibility products. Finally, the plurality of visibility products are transformed to generate an image. The concepts described herein may be relied upon to reconfigure or repurpose a phased-array receiver to achieve imaging. |
| FILED | Friday, May 06, 2016 |
| APPL NO | 15/570096 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02041 (20130101) G01B 9/02084 (20130101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/006 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/00 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/003 (20130101) G01S 13/90 (20130101) Antennas, i.e Radio Aerials H01Q 3/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551196 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Shuwu Wu (Yorba Linda, California); Ji Li (Broomfield, Colorado); Tyler Thomas (Fullerton, California); Howard E. Wan (Diamond Bar, California) |
| ABSTRACT | Technology for correcting a misalignment between an inertial measurement unit (IMU) and a moving platform is described. A first attitude of the moving platform can be identified based on a truth source. A second attitude of the moving platform can be calculated using IMU measurements. A delta attitude can be calculated from a difference between the first attitude and the second attitude. Natural error can be removed from the delta attitude to produce an angular misalignment value between axes of the IMU and axes of the moving platform. A total misalignment value can be determined by adding the angular misalignment value to a baseline misalignment value. The IMU can incorporate the total misalignment value for subsequent attitude measurements of the moving platform in order to produce substantially accurate attitude measurements of the moving platform when the axes of the IMU are misaligned with the axes of the moving platform. |
| FILED | Thursday, April 30, 2015 |
| APPL NO | 14/701254 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/165 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551283 | Ghosh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore County (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| INVENTOR(S) | Upal Ghosh (Ellicott City, Maryland); Mehregan Jalalizadeh (Huntington Beach, California) |
| ABSTRACT | A vibrating platform for the deploying of passive sampling devices in sediments and other media to be sampled. The vibrating platform can greatly enhance the rate of mass transfer of analytes, such as polycyclic aromatic hydrocarbons and polychlorinated biphenyls, into passive sampler material by disrupting the formation of a depletion layer in proximity of the passive sampler material. |
| FILED | Thursday, September 28, 2017 |
| APPL NO | 15/718119 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) Original (OR) Class G01N 1/4055 (20130101) G01N 33/1826 (20130101) G01N 2001/1025 (20130101) G01N 2001/4061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551319 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Han Cao (San Diego, California); Jonas O. Tegenfeldt (Lund, Sweden); Stephen Chou (Princeton, New Jersey); Robert H. Austin (Princeton, New Jersey) |
| ABSTRACT | A fluidic chip includes at least one nanochannel array, the nanochannel array including a surface having a nanofluidic area formed in the material of the surface; a microfluidic area on said surface; a gradient interface area having a gradual elevation of height linking the microfluidic area and the nanofluidic area; and a sample reservoir capable of receiving a fluid in fluid communication with the microfluidic area. In another embodiment, a fluidic chip includes at least one nanochannel array, the nanochannel array includes a surface having a nanofluidic area formed in the material of the surface; a microfluidic area on said surface; and a gradient interface area linking the microfluidic area and the nanofluidic area, where the gradient interface area comprises a plurality of gradient structures, and the lateral spacing distance between said gradient structures decreases towards said nanofluidic area; and a sample reservoir capable of receiving a fluid in fluid communication with the microfluidic area. |
| FILED | Monday, July 31, 2017 |
| APPL NO | 15/664196 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 2200/12 (20130101) B01L 2200/027 (20130101) B01L 2200/0663 (20130101) B01L 2300/0654 (20130101) B01L 2300/0896 (20130101) B01L 2400/086 (20130101) B01L 2400/0415 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/058 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00119 (20130101) B81C 2201/0157 (20130101) B81C 2201/0159 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Original (OR) Class G01N 33/48721 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/2008 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551330 | Atre et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); STICHTING VOOR FUNDAMENTEEL ONDERZOEK DER MATERIE (Utrecht, Netherlands); Ashwin C. Atre (Stanford, California); Jennifer A. Dionne (Stanford, California); Benjamin Brenny (Utrecht, Netherlands); Toon Coenen (Utrecht, Netherlands); Albert Polman (Utrecht, Netherlands) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); STICHTING VOOR FUNDAMENTEEL ONDERZOEK DER MATERIE (Utrecht, Netherlands) |
| INVENTOR(S) | Ashwin C. Atre (Stanford, California); Jennifer A. Dionne (Stanford, California); Benjamin Brenny (Utrecht, Netherlands); Toon Coenen (Utrecht, Netherlands); Albert Polman (Utrecht, Netherlands) |
| ABSTRACT | In one aspect, a cathodoluminescence (CL) spectroscopic tomography device includes a sample stage to support a sample. An electron beam source scans an electron beam over the sample to yield light emission by the sample. A reflective element directs the light emission by the sample to a light detector. A controller controls operation of the sample stage, the electron beam source, and the light detector. In one aspect, a CL spectroscopic tomography device includes an electron beam source which directs an electron beam at an object to yield an emission by the object. A detector detects the emission. A controller receives information from the detector related to the detected emission. The controller derives a two-dimensional (2D) CL map from the information related to the detected emission, and derives a three-dimensional (3D) CL tomogram from the 2D CL map. |
| FILED | Wednesday, April 22, 2015 |
| APPL NO | 15/305329 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/0073 (20130101) A61B 5/0075 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/2254 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551338 | Potyrailo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Zhexiong Tang (Niskayuna, New York); Igor Tokarev (Waterford, New York); Binil Itty Ipe Kandapallil (Summerville, South Carolina) |
| ABSTRACT | The subject matter of the present disclosure generally relates to systems and methods for sensing analytes with a high selectivity and low responses to interferences in an environment. In one embodiment, a sensor was developed which comprises a sensor electrode, a coupling element operationally coupled to a discrete segment of the sensor electrode, and an activation material in operational contact with the coupling element and configured to induce an irreversible sensor response for a selected sensing application. |
| FILED | Thursday, September 29, 2016 |
| APPL NO | 15/280028 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/221 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551368 | McNeil et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Anne J. McNeil (Dexter, Michigan); Kelsey N. Carter (Ann Arbor, Michigan) |
| ABSTRACT | A method and kit for detecting the presence of lead in a solid sample is disclosed. The solid sample is brought into contact with a nonaqueous solution of a dithiocarbamate capable of forming a gel upon contact with lead, with the formation of a gel showing that lead is present in the solid sample. |
| FILED | Friday, May 01, 2015 |
| APPL NO | 15/307021 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 31/22 (20130101) G01N 33/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551423 | Siddiqui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey Siddiqui (Sacramento, California); Kevin Geoghegan (Roseville, California); Tom Shepherd (Roseville, California) |
| ABSTRACT | The present invention relates to a system and method for the simultaneous testing of radiation, environmental and electrical reliability of multiple semiconductor devices. The system provides a simultaneous simulation of the space environment in which a device under test (DUT) is expected to operate under thereby providing an accurate test environment. One or more DUTs are simultaneously subject to each of a radiating dose, electrical bias and varying temperature. Additionally, each of the above may be varied over a range of values to provide test data under multiple testing conditions. Finally, a method for operating the system is provided which ensures reliable and high fidelity data from the system. The system comprises seven (7) interconnected subsystems, an electrical environmental subsystem, a radiation subsystem, an environmental control system, a radiation source control system, a temperature monitoring subsystem, an electrical stimulation and data acquisition subsystem and a data processing and analysis subsystem. |
| FILED | Wednesday, January 13, 2016 |
| APPL NO | 14/994700 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/003 (20130101) Original (OR) Class G01R 31/265 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551427 | Beck |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | William A. Beck (Woodbine, Maryland) |
| ABSTRACT | A method for determining a two-dimensional spectrum of a specified carrier having a specified mobility and density in a material of an electronic device, the method including performing a magnetic field-dependent Hall measurement on the material of the electronic device; determining, using the magnetic field-dependent Hall measurement, a probability density function of a conductance of the material of the electronic device, wherein the probability density function describes a spectrum of a plurality of m-carriers, wherein the plurality of m-carriers includes the specified carrier having the specified mobility and density; and determining an electrical transport of a plurality of electrons and holes inside the material of the electronic device by observing a variation of the probability density function with any of the specified mobility and density of the specified carrier. |
| FILED | Tuesday, February 14, 2017 |
| APPL NO | 15/431941 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2648 (20130101) Original (OR) Class G01R 33/07 (20130101) G01R 33/1253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551583 | Stone |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wavefront Research, Inc. (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | Wavefront Research, Inc. (Northampton, Pennsylvania) |
| INVENTOR(S) | Thomas W. Stone (Hellertown, Pennsylvania) |
| ABSTRACT | Methods and systems for optical interconnection. |
| FILED | Monday, May 07, 2018 |
| APPL NO | 15/972897 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/06 (20130101) G02B 6/423 (20130101) G02B 6/4249 (20130101) G02B 6/4292 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551719 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Richard S Kim (Mason, Ohio); Attila A Szep (Bellbrook, Ohio); Michael L Fanto (Rome, New York); Paul M Alsing (Chittenango, New York); Gordon E Lott (Beavercreek, Ohio); Christopher C Tison (Boynton Beach, Florida) |
| ABSTRACT | An electro-optical directional coupler is provided having a substrate and a first and second optical waveguide formed on the substrate, where the second waveguide extends adjacent to and parallel with the first waveguide for at least one interaction length. The interaction length has a first end and a second end such that an optical signal applied only to one of the first and second waveguides couples to the other of the first and second waveguides between the ends. A first electrode is proximate the first and second waveguides and between the ends of the interaction length. A first voltage applied to the first electrode independently tunes a coupling of a TE mode. A second electrode located proximate the first and second waveguides and the first electrode and between the ends of the interaction length. A second voltage applied to the second electrode independently tunes a coupling of a TM mode. |
| FILED | Monday, February 13, 2017 |
| APPL NO | 15/430775 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0136 (20130101) G02F 1/3133 (20130101) G02F 3/00 (20130101) Original (OR) Class G02F 2201/12 (20130101) G02F 2202/20 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551919 | Keesling |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Applied Invention, LLC (Burbank, California) |
| ASSIGNEE(S) | Applied Invention, LLC (Burbank, California) |
| INVENTOR(S) | Michael Keesling (Agoura Hills, California) |
| ABSTRACT | Various embodiments relate to apparatuses and methods of using light transmission thought compressed living tissue to detect force. Transmission of light through living tissue such as a finger is affected by how much the tissue is compressed, for example by the finger being pressing on a surface. Light is introduced into the tissue, passes through the tissue, and a sensor receives the light exiting the tissue. The compression of the tissue can be determined using various characteristics of the received light, such as the light intensity, as determined based at least partly on sensor readings. |
| FILED | Monday, May 20, 2019 |
| APPL NO | 16/417503 |
| ART UNIT | 2623 — Selective Visual Display Systems |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/16 (20130101) Electric Digital Data Processing G06F 3/014 (20130101) Original (OR) Class G06F 3/017 (20130101) G06F 3/0304 (20130101) G06F 3/0325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10552250 | Biran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Giora Biran (Zichron-Yaakov, Israel); Pradip Bose (Yorktown Heights, New York); Alper Buyuktosunoglu (White Plains, New York); Pierce I-Jen Chuang (Briarcliff Manor, New York); Preetham M. Lobo (Bangalore, India); Ramon Bertran Monfort (New York, New York); Phillip John Restle (Katonah, New York); Christos Vezyrtzis (New Rochelle, New York); Tobias Webel (Schwaebisch Gmuend, Germany) |
| ABSTRACT | Techniques facilitating voltage droop reduction and/or mitigation in a processor core are provided. In one example, a system can comprise a memory that stores, and a processor that executes, computer executable components. The computer executable components can comprise an observation component that detects one or more events at a first stage of a processor pipeline. An event of the one or more events can be a defined event determined to increase a level of power consumed during a second stage of the processor pipeline. The computer executable components can also comprise an instruction component that applies a voltage droop mitigation countermeasure prior to the increase of the level of power consumed during the second stage of the processor pipeline and a feedback component that provides a notification to the instruction component that indicates a success or a failure of a result of the voltage droop mitigation countermeasure. |
| FILED | Tuesday, October 10, 2017 |
| APPL NO | 15/729242 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/28 (20130101) G06F 1/305 (20130101) G06F 1/324 (20130101) G06F 11/0721 (20130101) G06F 11/0793 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10552278 | Jenkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Keith A. Jenkins (Sleepy Hollow, New York); Barry P. Linder (Hastings-on-Hudson, New York); Emily A. Ray (Hastings on Hudson, New York); Raphael P. Robertazzi (Ossining, New York); Peilin Song (Lagrangeville, New York); James H. Stathis (Poughquag, New York); Kevin G. Stawiasz (Bethel, Connecticut); Franco Stellari (Waldwick, New Jersey); Alan J. Weger (Mohegan Lake, New York); Emmanuel Yashchin (Yorktown Heights, New York) |
| ABSTRACT | A method and system are provided for chip testing. The method includes selectively deploying a chip for future use or discarding the chip to prevent the future use, responsive to a stress history of the chip determined using a non-destructive test procedure. The test procedure includes ordering each of a plurality of functional patterns by a respective minimum operating period corresponding thereto. The test procedure further includes ranking each of the plurality of patterns based on at least one preceding available pattern to provide a plurality of pattern ranks. The test procedure also includes calculating a sum by summing the plurality of pattern ranks. The sum calculated during an initial performance of the test procedure is designated as a baseline, and the sum calculated during a subsequent performance of the test procedure is compared to a threshold derived from the baseline to determine the stress history of the chip. |
| FILED | Friday, July 13, 2018 |
| APPL NO | 16/035032 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/008 (20130101) G06F 11/24 (20130101) G06F 11/263 (20130101) G06F 11/2236 (20130101) Original (OR) Class G06F 11/2273 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10552461 | Katz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Edward G. Katz (Washington, District of Columbia); Kristen M. Summers (Takoma Park, Maryland) |
| ABSTRACT | A method, system and a computer program product are provided for scoring candidate answers for geographic relevance by identifying document location information that is associated with a document, associating each token in the document with the document location information, and then comparing geographic foci identified for a candidate answer from the tokens with geographic foci identified for an input question to generate a geographic relevance score for the candidate answer to the input question. |
| FILED | Friday, September 16, 2016 |
| APPL NO | 15/267568 |
| ART UNIT | 2153 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/29 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10552740 | Alpert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Charles J. Alpert (Austin, Texas); Pallab Datta (San Jose, California); Myron D. Flickner (San Jose, California); Zhuo Li (Cedar Park, Texas); Dharmendra S. Modha (San Jose, California); Gi-Joon Nam (Austin, Texas) |
| ABSTRACT | Embodiments of the present invention relate to providing fault-tolerant power minimization in a multi-core neurosynaptic network. In one embodiment of the present invention, a method of and computer program product for fault-tolerant power-driven synthesis is provided. Power consumption of a neurosynaptic network is modeled as wire length. The neurosynaptic network comprises a plurality of neurosynaptic cores connected by a plurality of routers. At least one faulty core of the plurality of neurosynaptic cores is located. A placement blockage is modeled at the location of the at least one faulty core. A placement of the neurosynaptic cores is determined by minimizing the wire length. |
| FILED | Monday, November 10, 2014 |
| APPL NO | 14/537844 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10552749 | Riabov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Anton Viktorovich Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (Port Chester, New York); Octavian Udrea (Ossining, New York) |
| ABSTRACT | A mechanism is provided for computing a solution to a plan recognition problem. The plan recognition problem includes the model and a partially ordered sequence of observations or traces. The plan recognition is transformed into an AI planning problem such that a planner can be used to compute a solution to it. The approach is general. It addresses unreliable observations: missing observations, noisy observations (or observations that need to be discarded), and ambiguous observations). The approach does not require plan libraries or a possible set of goals. A planner can find either one solution to the resulting planning problem or multiple ranked solutions, which maps to the most plausible solution to the original problem. |
| FILED | Tuesday, December 08, 2015 |
| APPL NO | 14/962714 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10552764 | Carlin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aptima, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | Aptima, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Alan Carlin (Waltham, Massachusetts) |
| ABSTRACT | In one embodiment of the invention, a training model for students is provided that models how to present training items to students in a computer based adaptive trainer. The training model receives student performance data and uses the training model to infer underlying student skill levels throughout the training sequence. Some embodiments of the training model also comprise machine learning techniques that allow the training model to adapt to changes in students skills as the student performs on training items presented by the training model. Furthermore, the training model may also be used to inform a training optimization model, or a learning model, in the form of a Partially Observable Markov Decision Process (POMDP). |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/395574 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) G06N 20/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553005 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Chung-Ching Lin (White Plains, New York); Sharathchandra U. Pankanti (Darien, Connecticut); Karthikeyan Natesan Ramamurthy (Yorktown Heights, New York); Aleksandr Y. Aravkin (Bronx, New York); John R. Smith (New York, New York) |
| ABSTRACT | A method and system of stitching a plurality of image views of a scene, including grouping matched points of interest in a plurality of groups, and determining a similarity transformation with smallest rotation angle for each grouping of the matched points. The method further includes generating virtual matching points on non-overlapping area of the plurality of image views and generating virtual matching points on overlapping area for each of the plurality of image views. |
| FILED | Friday, February 10, 2017 |
| APPL NO | 15/430057 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) G06K 9/4609 (20130101) G06K 9/4638 (20130101) G06K 9/4671 (20130101) G06K 9/6211 (20130101) G06K 2009/2045 (20130101) G06K 2009/6213 (20130101) Image Data Processing or Generation, in General G06T 3/4038 (20130101) G06T 5/006 (20130101) G06T 7/33 (20170101) G06T 11/60 (20130101) Original (OR) Class G06T 2207/10032 (20130101) G06T 2207/20104 (20130101) G06T 2207/20221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553022 | Massaro |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America US Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Richard D Massaro (Burke, Virginia) |
| ABSTRACT | This invention is a system for photogrammetric analysis of full motion video (FMV), which converts FMV to image files, extracts metadata, and produces accurate 2-D and 3-D geospatial images in real time. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 15/720133 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 16/75 (20190101) G06F 16/78 (20190101) G06F 16/735 (20190101) Image Data Processing or Generation, in General G06T 17/05 (20130101) G06T 17/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553090 | Tolliver et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Laura C. Tolliver (Mt. Pleasant, South Carolina); Peyton B. Cavaroc (Charleston, South Carolina); Kevin P. Votapka (Charleston, South Carolina); Robert R. Regal (Charleston, South Carolina); Lucas D. Powell (Charleston, South Carolina); Hunter J. Smith (Charleston, South Carolina) |
| ABSTRACT | A device for signaling including a top member adjacent to a bottom member, a button adjacent to the top member, a sensor adjacent to the top member, a radio adjacent to the top member, a microprocessor board adjacent to the radio, a battery adjacent to the microprocessor board, and a switch adjacent to the bottom member. A button slot and sensor hole formed through the top member. The button is received in the button slot and the sensor in the sensor slot. The microprocessor board further comprises a light emitting diode. The bottom member has a bottom recess and a switch slot. The switch is received in the switch slot. The top member has a sensor recess and a screw hole. The sensor is retained in the sensor recess. The bottom member has a screw recess. The radio, microprocessor board, and battery are slidably received in the bottom slot. |
| FILED | Thursday, August 23, 2018 |
| APPL NO | 16/110774 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 13/19 (20130101) Original (OR) Class G08B 13/19602 (20130101) G08B 25/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553342 | Lazarus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Nathan S. Lazarus (Bethesda, Maryland); Christopher D. Meyer (Silver Spring, Maryland) |
| ABSTRACT | A deformable inductive device includes an elastomer material having at least one deformable electrode and a liquid magnetic core formed in the elastomer material and containing a magnetic liquid. Depending on the device's configuration, the deformable element may be embedded in, attached to, or in close proximity with the liquid magnetic core. In some embodiments, the deformable inductive device may be configured as an inductor, solenoid, or transformer and the deformable electrode is at least partially embedded in the liquid magnetic core, for instance. In another embodiment, the deformable inductive device may be configured as part of a wireless power transfer system which includes a coil and a magnetic backplane having the liquid magnetic core with the coil being attached to or in close proximity to the magnetic backplane. |
| FILED | Wednesday, July 13, 2016 |
| APPL NO | 15/209115 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/022 (20130101) Original (OR) Class H01F 27/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553414 | Youngner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morristown, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Daniel Youngner (Maple Grove, Minnesota); Thomas Ohnstein (Roseville, Minnesota) |
| ABSTRACT | Devices, methods, and systems for trapping multiple ions are described herein. One device includes two or more ovens wherein each oven includes a heating element and a cavity for emitting atoms of a particular atomic species from an atomic source substance, a substrate having a number of apertures that allow atoms emitted from the atomic source substance to exit the oven and enter an ion trapping area and wherein each oven is positioned at a different ion loading area within the ion trapping area, and a plurality of electrodes that can be charged and wherein the charge can be used to selectively control the movement of a particular ion from a particular loading area to a particular ion trap location. |
| FILED | Friday, June 26, 2015 |
| APPL NO | 14/752368 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) H01J 49/062 (20130101) Original (OR) Class H01J 49/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553740 | Cornfeld et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| INVENTOR(S) | Arthur Cornfeld (Sandy Springs, Georgia); Mark A. Stan (Albuquerque, New Mexico) |
| ABSTRACT | A multijunction solar cell includes an InGaAs buffer layer and an InGaAlAs grading interlayer disposed below, and adjacent to, the InGaAs buffer layer. The grading interlayer achieves a transition in lattice constant from one solar subcell to another solar subcell. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 15/965219 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/06 (20130101) Original (OR) Class H01L 31/184 (20130101) H01L 31/0693 (20130101) H01L 31/1844 (20130101) H01L 31/03046 (20130101) H01L 31/06875 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553743 | Yoon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Woojun Yoon (Fairfax, Virginia); Phillip Jenkins (Cleveland Heights, Ohio); Robert J. Walters (Alexandria, Virginia); David Scheiman (Alexandria, Virginia) |
| ABSTRACT | A novel, low cost method for manufacturing flexible crystalline ultra-thin Si solar cells using previously fabricated inflexible crystalline Si solar cells. A stack of metal layers is coated onto a front side of previously completed inflexible crystalline Si solar cells. The stack serves as a bonding layer as well as an electrically conducting layer between the inflexible solar cell and the carrier substrate. The front side of the coated inflexible Si solar cell is bonded onto the carrier substrate. Back side layers from the starting inflexible solar cell are removed, as is much of the base layer, so that only a thin base layer remains, with the thin base layer and emitter region having a total thickness of between 1 μm and 30 μm and the final cell having a total thickness of about 10 to about 125 μm. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196093 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/182 (20130101) H01L 31/186 (20130101) H01L 31/0682 (20130101) H01L 31/1804 (20130101) H01L 31/1896 (20130101) Original (OR) Class H01L 31/02363 (20130101) H01L 31/03921 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553751 | Mi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Royal Institution for the Advancement of Learning/McGill University (Montreal, Canada) |
| ASSIGNEE(S) | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (Montreal, Quebec, Canada) |
| INVENTOR(S) | Zetian Mi (Verdun, Canada); Songrui Zhao (Montreal, Canada); Renjie Wang (Montreal, Canada) |
| ABSTRACT | GaN-based nanowire heterostructures have been intensively studied for applications in light emitting diodes (LEDs), lasers, solar cells and solar fuel devices. Surface charge properties play a dominant role on the device performance and have been addressed within the prior art by use of a relatively thick large bandgap AlGaN shell covering the surfaces of axial InGaN nanowire LED heterostructures has been explored and shown substantial promise in reducing surface recombination leading to improved carrier injection efficiency and output power. However, these lead to increased complexity in device design, growth and fabrication processes thereby reducing yield/performance and increasing costs for devices. Accordingly, there are taught self-organising InGaN/AlGaN core-shell quaternary nanowire heterostructures wherein the In-rich core and Al-rich shell spontaneously form during the growth process. |
| FILED | Tuesday, April 02, 2019 |
| APPL NO | 16/372946 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) Original (OR) Class H01L 33/007 (20130101) H01L 33/08 (20130101) H01L 33/18 (20130101) H01L 33/32 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/021 (20130101) H01S 5/1042 (20130101) H01S 5/4006 (20130101) H01S 5/32341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10554015 | Tassev |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright Patterson AFB, Ohio) |
| INVENTOR(S) | Vladimir Tassev (Beavercreek, Ohio) |
| ABSTRACT | A method of making a quasi-phase-matching (QPM) structure comprising the steps of: applying a pattern to a substrate to define a plurality of growth regions and a plurality of voids; growing in a growth chamber a crystalline inorganic material on only the growth regions in the pattern, the crystalline inorganic material having a first polarity; applying an electric field within the growth chamber containing the patterned substrate with the crystalline inorganic material, wherein the electric field reaches throughout the growth chamber; and growing a crystalline organic material having a second polarity in the voids formed in the inorganic material under the influence of the electric field to influence the magnitude and the direction of the second polarity of the crystalline organic material, wherein the second polarity of the crystalline organic material is influenced to be different from the first polarity of the crystalline inorganic material in magnitude and/or direction. |
| FILED | Thursday, January 25, 2018 |
| APPL NO | 15/879721 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/04 (20130101) C30B 30/02 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0604 (20130101) Original (OR) Class H01S 2304/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10554017 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Jung Han (Woodbridge, Connecticut); Yufeng Li (Shaanxi, China PRC); Ge Yuan (New Haven, Connecticut) |
| ABSTRACT | Edge-emitting laser diodes having high confinement factors and lattice-matched, porous cladding layers are described. The laser diodes may be formed from layers of III-nitride material. A cladding layer may be electrochemically etched to form a porous cladding layer having a high refractive index contrast with an active junction of the device. A transparent conductive oxide layer may be deposited to form a top-side cladding layer with high refractive index contrast and low resistivity. |
| FILED | Thursday, May 19, 2016 |
| APPL NO | 15/574739 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/306 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/305 (20130101) H01S 5/2009 (20130101) Original (OR) Class H01S 5/2081 (20130101) H01S 5/3211 (20130101) H01S 5/3213 (20130101) H01S 5/3219 (20130101) H01S 5/34333 (20130101) H01S 2304/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10554207 | Herr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Anna Y. Herr (Ellicott City, Maryland); Quentin P. Herr (Ellicott City, Maryland); Ryan Edward Clarke (Hanover, Maryland); Harold Clifton Hearne, III (Baltimore, Maryland); Alexander Louis Braun (Baltimore, Maryland); Randall M. Burnett (Catonsbille, Maryland); Timothy Chi-Chao Lee (Gaithersburg, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Anna Y. Herr (Ellicott City, Maryland); Quentin P. Herr (Ellicott City, Maryland); Ryan Edward Clarke (Hanover, Maryland); Harold Clifton Hearne, III (Baltimore, Maryland); Alexander Louis Braun (Baltimore, Maryland); Randall M. Burnett (Catonsbille, Maryland); Timothy Chi-Chao Lee (Gaithersburg, Maryland) |
| ABSTRACT | Non-destructive read out (NDRO) circuits are provided for use in reciprocal quantum logic (RQL) superconducting systems. Each NDRO circuit includes a “body” circuit that provides a single or multi-state sub-critical bias current to one or many independent “tail” circuitries. Each “tail” has minimal effect on the “body” thereby preventing any interference or destruction to the state of the “body” circuitry. The circuits reduce device count and thereby increase circuit density, simplify and reduce the cost of fabrication, and provide functionality not available in existing designs, such as the ability to write a state and read it in the same operation cycle. The NDRO circuits provide more compact unit cells useful in memory or logic arrays, demanding fewer resources with increased functionality. The circuits also provide compact cells for AND, AND-OR, A-NOT-B, inverter, multiplexer, and demultiplexer gates. |
| FILED | Tuesday, July 31, 2018 |
| APPL NO | 16/051058 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 11/44 (20130101) Pulse Technique H03K 3/38 (20130101) H03K 19/195 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10554233 | Dinc et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Tolga Dinc (New York, New York); Mark A. Ferriss (Tarrytown, New York); Daniel Joseph Friedman (Sleepy Hollow, New York); Wooram Lee (Briarcliff Manor, New York); Bodhisatwa Sadhu (Fishkill, New York); Alberto Valdes Garcia (Chappaqua, New York) |
| ABSTRACT | Techniques that facilitate reconfigurable transmission of a radar frequency signal are provided. In one example, a system includes a signal generator and a power modulator. The signal generator provides a radar waveform signal from a set of radar waveform signals. The power modulator divides a local oscillator signal associated with a first frequency and a first amplitude into a first local oscillator signal and a second local oscillator signal. The power modulator also generates a radio frequency signal associated with a second frequency and a second amplitude based on the radar waveform signal, the first local oscillator signal and the second local oscillator signal. |
| FILED | Thursday, August 03, 2017 |
| APPL NO | 15/667682 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/03 (20130101) G01S 7/35 (20130101) G01S 7/282 (20130101) G01S 13/10 (20130101) G01S 13/34 (20130101) G01S 13/76 (20130101) G01S 13/284 (20130101) G01S 13/325 (20130101) G01S 2013/0272 (20130101) Demodulation or Transference of Modulation From One Carrier to Another H03D 7/1441 (20130101) H03D 7/1458 (20130101) H03D 7/1483 (20130101) Amplifiers H03F 3/20 (20130101) Transmission H04B 1/0082 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10554288 | Gandy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Applied Minds, LLC (Burbank, California) |
| ASSIGNEE(S) | Applied Minds, LLC (Burbank, California) |
| INVENTOR(S) | Charles L. Gandy (Annapolis, Maryland); Clinton Blake Hope (Los Angeles, California); Edward Francis Adams (Los Angeles, California); Donald Gregory Lariviere (Glendale, California); Houstin L. Lichtenwalner (Macungie, Pennsylvania) |
| ABSTRACT | Disclosed are passive reflector radio communications systems, such as for UHF frequencies or greater than UHF frequencies, and related deployment systems and devices that provide underground communications. Embodiments of the system include reflector elements to provide passive radio communications, structural frameworks to support and orient the reflector elements, methods for calculating reflector size, shape, and position corresponding to a desired wavelength, and deployment methods and devices to install the communication system at a desired location. The passive reflectors can be placed in a folded or otherwise compact mode, for transport into underground tunnels. Once at the desired installation location, the system can be installed, with the reflectors positioned appropriately for the radio frequencies used at the location. Some of the embodiments include any of vertical or horizontal foldable reflector poles, reflective sheets, reflective mesh sheets and/or ropes, inflatable reflective pucks, and rapid deployment systems and methods. |
| FILED | Monday, January 22, 2018 |
| APPL NO | 15/877281 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 7/145 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10554312 | Santra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Siddhartha Santra (Hyattsville, Maryland); Brian T. Kirby (Baltimore, Maryland); Vladimir S. Malinovsky (Clifton, New Jersey); Michael Brodsky (Millburn, New Jersey) |
| ABSTRACT | Methods and systems for measuring interferometric visibility of telescopic signals using resources having imperfect quantum entanglement are disclosed. The novel methodology employed by embodiments of the present invention takes into account the difficulty in creating entanglement between distance telescopes, and describes how to incorporate problems associated with distributing quantum entanglement into the measurement procedure. This allows the distance that two telescopes in an optical array are spaced apart to be increased while still interacting. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/979020 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 23/04 (20130101) Electric Digital Data Processing G06F 17/14 (20130101) G06F 17/15 (20130101) G06F 17/16 (20130101) Transmission H04B 10/70 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10548608 | Boyle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | Lawrenece Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Anthony J. Boyle (College Station, Texas); Keith Hearon (Augusta, Georgia); Duncan J. Maitland (College Station, Texas); Landon D. Nash (College Station, Texas); Thomas S. Wilson (San Leandro, California) |
| ABSTRACT | An embodiment of the invention is a shape memory polymer (SMP) foam designed to recover its original shape through exposure to a solvent. Thermo-responsive SMPs are polymers designed to maintain a programmed secondary shape until heated above their transition temperature, upon which the polymer recovers its original, or primary, shape. The thermo-responsive SMP foam is programmed to its secondary shape prior to use, typically compression of the foam to a small volume, and remains in this programmed shape until exposed to a selected solvent such as dimethyl sulfoxide or ethyl alcohol. Upon exposure to the solvent, the transition temperature of the SMP foam decreases below the temperature of the environment and the SMP foam actuates to its primary shape. The SMP foam is tailored to actuate upon exposure to specific solvents while minimizing or preventing actuation when exposed to water or other solvents. This selective solvent actuation can be used to increase working time of a SMP foam device, that is, the time allowed for use of a device without undesired actuation, while maintaining functional SMP actuation. Solvent actuated SMP foams can be used in various applications including, but not limited to, treatment of aneurysms and arterio-venous malformations, tissue engineering, and wound healing. |
| FILED | Tuesday, June 07, 2016 |
| APPL NO | 15/579217 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/12031 (20130101) A61B 17/12113 (20130101) A61B 17/12181 (20130101) Original (OR) Class A61B 2017/00871 (20130101) A61B 2017/00938 (20130101) A61B 2017/00964 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/06 (20130101) A61L 31/14 (20130101) A61L 31/146 (20130101) A61L 2400/16 (20130101) A61L 2430/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549214 | DiPrete et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, North Carolina) |
| INVENTOR(S) | David P. DiPrete (Evans, Georgia); Donald J. Pak (Martinez, Georgia); Cecilia C. DiPrete (Evans, Georgia); Scott H. Reboul (Aiken, South Carolina); Tad S Whiteside (Aiken, South Carolina) |
| ABSTRACT | A device for collection of residue from separation columns. A manifold provides for multiple sample ports that are fluidly connected to a vacuum port by at least one channel. Residue from the separation columns is pulled through the sample ports, into the channel, and then to the vacuum port. From the vacuum port the residue can be moved, under the force of the vacuum, directly to a drain or to a collection vessel connected with a drain. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 15/455262 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/22 (20130101) Original (OR) Class Chemical or Physical Laboratory Apparatus for General Use B01L 3/00 (20130101) B01L 3/50255 (20130101) B01L 2400/049 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 1/405 (20130101) G01N 30/06 (20130101) G01N 30/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549229 | Baxter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Larry Baxter (Orem, Utah); Nathan Davis (Bountiful, Utah) |
| ASSIGNEE(S) | Hall Labs LLC (Provo, Utah) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); Nathan Davis (Bountiful, Utah) |
| ABSTRACT | Devices, systems, and methods for separating a vapor from a gas are disclosed. A gas is passed through a direct-contact exchanger. The exchanger using a contact liquid to cool the gas. The gas comprises a vapor. A portion of the vapor is condensed as the gas passes through the direct-contact exchanger, producing a product liquid and a vapor-depleted gas. The product liquid is immiscible in the contact liquid. The product liquid is gravity settled from the contact liquid such that the contact liquid and the product liquid separate in the direct-contact exchanger. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/724725 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 17/0208 (20130101) B01D 53/002 (20130101) Original (OR) Class B01D 53/18 (20130101) B01D 53/1493 (20130101) B01D 2252/103 (20130101) B01D 2252/2021 (20130101) B01D 2257/80 (20130101) B01D 2257/7022 (20130101) B01D 2258/0283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549261 | Nenoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Tina M. Nenoff (Albuquerque, New Mexico); Dorina Florentina Sava Gallis (Albuquerque, New Mexico); Marie Vernell Parkes (Albuquerque, New Mexico); Jeffery Greathouse (Albuquerque, New Mexico) |
| ABSTRACT | MOFs are disclosed that can efficiently adsorb oxygen from a gas stream, such as air. Systems and methods are also disclosed that utilize MOFs to separate oxygen from a gas stream. The separated oxygen may be used in a commercial process such as a combustion process. |
| FILED | Monday, May 20, 2019 |
| APPL NO | 16/417181 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/04 (20130101) B01D 2253/204 (20130101) B01D 2257/104 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550010 | Darling et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Seth B. Darling (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Anil U. Mane (Naperville, Illinois) |
| ABSTRACT | A method of fabricating an oleophilic foam includes providing a foam comprising a base material. The base material is coated with an inorganic material using at least one of an atomic layer deposition (ALD), a molecular layer deposition (MLD) or sequential infiltration synthesis (SIS) process. The SIS process includes at least one cycle of exposing the foam to a first metal precursor for a first predetermined time and a first partial pressure. The first metal precursor infiltrates at least a portion of the base material and binds with the base material. The foam is exposed to a second co-reactant precursor for a second predetermined time and a second partial pressure. The second co-reactant precursor reacts with the first metal precursor, thereby forming the inorganic material on the base material. The inorganic material infiltrating at least the portion of the base material. The inorganic material is functionalized with an oleophilic material. |
| FILED | Friday, December 11, 2015 |
| APPL NO | 14/967021 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Separation B01D 15/265 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/223 (20130101) B01J 20/262 (20130101) B01J 20/3212 (20130101) B01J 20/3217 (20130101) B01J 20/3236 (20130101) B01J 20/3285 (20130101) B01J 20/3291 (20130101) B01J 20/28045 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/288 (20130101) Original (OR) Class C02F 2101/32 (20130101) C02F 2103/007 (20130101) C02F 2103/08 (20130101) C02F 2201/008 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550051 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Fanxing Li (Raleigh, North Carolina); Luke M. Neal (Raleigh, North Carolina) |
| ABSTRACT | Methods and systems are provided for oxidative dehydrogenation of a hydrocarbon feed stream to produce a product stream with improved ethylene yield. The methods can include the steps of (i) combining a recycle stream with the feed stream to form a reactor feed stream, (ii) contacting the reactor feed stream with an oxide-based redox catalyst to produce the product stream comprising ethylene and one or more byproducts selected from the group consisting of methane, ethane, other byproducts, and mixtures thereof, and (iii) removing all or a part of the methane and ethane from the product stream to produce the recycle stream. Systems for the oxidative dehydrogenation (ODH) of a hydrocarbon feed stream are also provided to produce a product stream with improved ethylene yield. The systems and methods can include an oxide-based redox catalyst, such as Mg6MnO8, Cu6PbO8, and Ni6MnO8. |
| FILED | Thursday, February 02, 2017 |
| APPL NO | 15/422743 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 5/42 (20130101) Original (OR) Class C07C 2523/34 (20130101) C07C 2523/835 (20130101) C07C 2523/889 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550139 | Dub et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Pavel A. Dub (Los Alamos, New Mexico); John Cameron Gordon (Los Alamos, New Mexico) |
| ABSTRACT | Embodiments of the present disclosure relate generally to novel achiral and chiral sulfur-, nitrogen- and phosphorus-containing ligands, designated as NNS-type, P(O)NS-type, PNS-type, SNNS-type, SNNP(O)-type, or SNNP-type polydentate ligands and transition metal complexes of these ligands, including iridium complexes having PNS-type and NNS-type ligands. The catalysts derived from these ligands and transition metal complexes may be used in a wide range of catalytic reactions, including hydrogenation and transfer hydrogenation of unsaturated organic compounds, dehydrogenation of alcohols and boranes, various dehydrogenative couplings, chemoselective hydrogenation of α,β-unsaturated alcohols, and other catalytic transformations. |
| FILED | Friday, December 09, 2016 |
| APPL NO | 15/375055 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/5304 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550343 | Patel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nikhil Manubhai Patel (Grand Forks, North Dakota) |
| ASSIGNEE(S) | Nikhil Manubhai Patel (Grand Forks, North Dakota) |
| INVENTOR(S) | Nikhil Manubhai Patel (Grand Forks, North Dakota) |
| ABSTRACT | The present invention discloses a gasifier and/or a gasification process that provides a long, uniform temperature zone in the gasifier, regardless of the particle size, chemical composition, and moisture content of the fuel by sandwiching a reduction zones between two oxidation zones. The gasifier and/or gasification process has a char that is more energy-dense and almost devoid of moisture that affords for an additional (or char) oxidation zone with a temperature that is higher than a first oxidation zone which is closer to a evaporation and devolatilization zone. As such, the additional (or char) oxidation zone contributes to augmenting the reduction zone temperature, thereby providing a favorable dual impact in improving syngas composition and near-complete conversion of the tar. |
| FILED | Monday, May 28, 2018 |
| APPL NO | 15/990725 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/08 (20130101) Original (OR) Class C10J 3/22 (20130101) C10J 3/26 (20130101) C10J 3/723 (20130101) C10J 2300/092 (20130101) C10J 2300/093 (20130101) C10J 2300/0946 (20130101) C10J 2300/0956 (20130101) C10J 2300/0959 (20130101) C10J 2300/0976 (20130101) C10J 2300/1246 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 1/024 (20130101) C10K 1/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550384 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Srivatsan Raman (Arlington, Massachusetts); Noah D. Taylor (Boston, Massachusetts); Jameson Rogers (Boston, Massachusetts) |
| ABSTRACT | The present invention relates to genetically modified bacteria and methods of optimizing genetically modified bacteria for the production of a metabolite. |
| FILED | Wednesday, February 26, 2014 |
| APPL NO | 14/775025 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1058 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550489 | Willit et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James L. Willit (Batavia, Illinois); Magdalena M. Tylka (Willow Springs, Illinois); Mark A. Williamson (Naperville, Illinois); Stanley G. Wiedmeyer (Glen Ellyn, Illinois); Javier Figueroa (Andover, Kansas) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | James L. Willit (Batavia, Illinois); Magdalena M. Tylka (Willow Springs, Illinois); Mark A. Williamson (Naperville, Illinois); Stanley G. Wiedmeyer (Glen Ellyn, Illinois); Javier Figueroa (Andover, Kansas) |
| ABSTRACT | A method for recycling molten salt from electrorefining processes, the method having the steps of collecting actinide metal using a first plurality of cathodes from an electrolyte bath, collecting rare earths metal using a second plurality of cathodes from the electrolyte bath, inserting the collected actinide metal and uranium into the bath, and chlorinating the inserted actinide metal and uranium. Also provided is a system for recycling molten salt, the system having a vessel adapted to receive and heat electrolyte salt, a first plurality of cathodes adapted to be removably inserted into the vessel, a second plurality of cathodes adapted to be removably inserted into the vessel, an anode positioned within the vessel so as to be coaxially aligned with the vessel, and a vehicle for inserting uranium into the salt. |
| FILED | Monday, July 11, 2016 |
| APPL NO | 15/206914 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 3/34 (20130101) Original (OR) Class C25C 7/005 (20130101) C25C 7/06 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550721 | Hafner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Matthew Troy Hafner (Honea Path, South Carolina); Gary Michael Itzel (Simpsonville, South Carolina); John McConnell Delvaux (Fountain Inn, South Carolina); Sandip Dutta (Greenville, South Carolina) |
| ABSTRACT | An apparatus is disclosed including a first and second article, a first interface volume disposed between and enclosed by the first article and second article, a cooling fluid supply, and at least one cooling fluid channel in fluid communication with the cooling fluid supply and the first interface volume. The first article includes a first material composition. The second article includes a second material composition. The at least one cooling fluid channel includes a heat exchange portion disposed in at least one of the first and second article downstream of the cooling fluid supply and upstream of the first interface volume. A turbine shroud is disclosed wherein the first and second articles are an outer and inner shroud. A turbine nozzle is disclosed wherein the first and second articles are an endwall and fairing. |
| FILED | Thursday, March 24, 2016 |
| APPL NO | 15/080201 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) F01D 9/041 (20130101) F01D 11/08 (20130101) F01D 25/12 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/213 (20130101) F05D 2260/2212 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550790 | Ravi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert Bosch LLC (Broadview, Illinois); Robert Bosch GmbH (Stuttgart, Germany) |
| ASSIGNEE(S) | Robert Bosch LLC (Broadview, Illinois); Robert Bosch GmbH (Stuttgart, Germany) |
| INVENTOR(S) | Nikhil Ravi (Mountain View, California); Joel Oudart (Mountain View, California); Shyam Jade (Birmingham, Michigan); Jason Schwanke (Southfield, Michigan); Li Jiang (Ann Arbor, Michigan) |
| ABSTRACT | An engine system uses data associated with at least one operating condition of an engine to set the engine system to an AI mode when the engine is in an SI mode 1) within first operating condition limits, and 2) when a rate of change of a first operating condition is within rate of change limits, maintain the engine system in the SI mode when the engine is outside of first operating condition limits or when the rate of change of the first operating condition is not within rate of change limits, set the engine system to the SI mode when the engine is in the AI mode outside second operating condition limits, and maintain the engine system in the AI mode when the engine is within second operating condition limits, wherein the second operating condition limits are different from the first operating condition limits. |
| FILED | Wednesday, December 30, 2015 |
| APPL NO | 14/984038 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Controlling Combustion Engines F02D 41/022 (20130101) F02D 41/0225 (20130101) F02D 41/3035 (20130101) F02D 41/3064 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550889 | Walter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Eric D. Walter (Richland, Washington); Jesse A. Sears, Jr. (Kennewick, Washington); Hardeep S. Mehta (Richland, Washington); David W. Hoyt (Richland, Washington) |
| ABSTRACT | Snap-in bushings are disclosed that enable sealing of sample chambers in MAS-NMR rotors for high pressure and/or high temperature operation that enhance pressure limits up to about 400 bar and temperature limits up to at least about 250° C. |
| FILED | Monday, August 01, 2016 |
| APPL NO | 15/225688 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 33/74 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550984 | Lynch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NuScale Power, LLC (Corvallis, Oregon) |
| ASSIGNEE(S) | NUSCALE POWER, LLC (Corvallis, Oregon) |
| INVENTOR(S) | John J. Lynch (Corvallis, Oregon); Edward A. Rodriguez (Corvallis, Oregon); Tamas R. Liszkai (Corvallis, Oregon) |
| ABSTRACT | A pipe restraint assembly includes a restraint body configured to be removably attached to a portion of pipe. The portion of pipe is associated with a postulated pipe failure associated with a release of high pressure fluid. A plurality of apertures penetrate through the restraint body and are positioned proximate to a location of the postulated pipe failure. The apertures are configured to provide a number of passageways for the fluid to exit from the location of the postulated pipe failure and to be released outside of the restraint body. One or more restraint devices maintain the position of the apertures relative to the location of the postulated pipe failure. |
| FILED | Friday, December 04, 2015 |
| APPL NO | 14/960007 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 23/167 (20130101) F16L 55/005 (20130101) Original (OR) Class F16L 55/07 (20130101) F16L 2201/20 (20130101) F16L 2201/30 (20130101) Nuclear Power Plant G21D 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551094 | Moghaddam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Saeed Moghaddam (Gainesville, Florida); Devesh Chugh (Gainesville, Florida); Sajjad Bigham (Hancock, Michigan) |
| ABSTRACT | An absorber or desorber contains one or more micro-channels that have a 3-D structured heat-exchanging surface and a membrane on the microchannel situated distal to the 3-D structured heat-exchanging surface, where the membrane is permeable to a solvent of a solution employed in the absorber or desorber. The 3-D structured surface promotes mixing of hot and cold solution between the 3-D structured heat-exchanging surface and a vapor-exchanging surface proximal to the membrane. The mixing reduces the differences in concentration and temperature of the bulk solution and the solution at the vapor-exchanging surface to enhance the efficiency and rate of absorption or desorption of the solvent. |
| FILED | Wednesday, June 29, 2016 |
| APPL NO | 15/196383 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 15/06 (20130101) F25B 17/02 (20130101) Original (OR) Class F25B 35/02 (20130101) F25B 37/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551097 | Cogswell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carrier Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | CARRIER CORPORATION (Palm Beach Gardens, Florida) |
| INVENTOR(S) | Frederick J. Cogswell (Glastonbury, Connecticut); Catherine Thibaud (South Windsor, Connecticut); Parmesh Verma (South Windsor, Connecticut); Bart A. Van Hassel (Weatogue, Connecticut); Thomas D. Radcliff (Vernon, Connecticut); Abdelrahman ElSherbini (Windsor, Connecticut); Robert A. Chopko (Baldwinsville, New York) |
| ABSTRACT | In one aspect, a refrigeration system is provided. The refrigeration system includes a refrigeration circuit configured to condition an air supply, a subcooling circuit configured to cool the refrigeration circuit, the subcooling circuit including a subcooling condenser, a subcooling heat exchanger, and at least one adsorption bed, and a heat generation system thermally coupled to the subcooling circuit. |
| FILED | Friday, September 11, 2015 |
| APPL NO | 15/526488 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 17/08 (20130101) F25B 25/02 (20130101) Original (OR) Class F25B 27/02 (20130101) F25B 40/02 (20130101) F25B 2315/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551120 | Baxter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Larry Baxter (Orem, Utah); Nathan Davis (Bountiful, Utah) |
| ASSIGNEE(S) | Hall Labs LLC (Provo, Utah) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); Nathan Davis (Bountiful, Utah) |
| ABSTRACT | A method for cryogenic cooling without fouling is disclosed. The method comprises providing a first cryogenic liquid saturated with a dissolved gas; expanding the first cryogenic liquid into a separation vessel, separating into a vapor, a second cryogenic liquid, and a first solid; drawing the vapor into a heat exchanger and the second cryogenic liquid and the first solid out of the separation vessel; cooling the vapor against a coolant through the heat exchanger, causing the vapor to form a third cryogenic liquid and a second solid, the second solid dissolving in the third cryogenic liquid; and combining the second cryogenic liquid and the first solid with the third cryogenic liquid, producing a final cooled slurry. In this manner, the cryogenic cooling is accomplished without fouling. |
| FILED | Monday, February 06, 2017 |
| APPL NO | 15/425412 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 5/006 (20130101) B01D 5/009 (20130101) B01D 5/0012 (20130101) B01D 5/0054 (20130101) B01D 5/0069 (20130101) B01D 5/0093 (20130101) B01D 8/00 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 5/00 (20130101) Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 3/061 (20130101) F25J 3/067 (20130101) Original (OR) Class F25J 3/0615 (20130101) F25J 3/0635 (20130101) F25J 3/0695 (20130101) F25J 2205/20 (20130101) F25J 2205/84 (20130101) F25J 2205/90 (20130101) F25J 2215/04 (20130101) F25J 2235/60 (20130101) F25J 2240/02 (20130101) F25J 2240/40 (20130101) F25J 2270/12 (20130101) F25J 2270/904 (20130101) F25J 2290/44 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551247 | Van Benthem et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Mark Van Benthem (Albuquerque, New Mexico); James A. Ohlhausen (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to methods for analyzing a chemical sample. For instance, the methods herein allow for global analysis of spectroscopy data in order to extract useful chemical properties from complicated multidimensional data. Such analysis can optionally employ data compression to further expedite computer-implemented computation. In particular, the methods herein provide global analysis of data matrices explained by both linear and non-linear terms. |
| FILED | Monday, March 28, 2016 |
| APPL NO | 15/082922 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) G01N 21/64 (20130101) G01N 23/083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551330 | Atre et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); STICHTING VOOR FUNDAMENTEEL ONDERZOEK DER MATERIE (Utrecht, Netherlands); Ashwin C. Atre (Stanford, California); Jennifer A. Dionne (Stanford, California); Benjamin Brenny (Utrecht, Netherlands); Toon Coenen (Utrecht, Netherlands); Albert Polman (Utrecht, Netherlands) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); STICHTING VOOR FUNDAMENTEEL ONDERZOEK DER MATERIE (Utrecht, Netherlands) |
| INVENTOR(S) | Ashwin C. Atre (Stanford, California); Jennifer A. Dionne (Stanford, California); Benjamin Brenny (Utrecht, Netherlands); Toon Coenen (Utrecht, Netherlands); Albert Polman (Utrecht, Netherlands) |
| ABSTRACT | In one aspect, a cathodoluminescence (CL) spectroscopic tomography device includes a sample stage to support a sample. An electron beam source scans an electron beam over the sample to yield light emission by the sample. A reflective element directs the light emission by the sample to a light detector. A controller controls operation of the sample stage, the electron beam source, and the light detector. In one aspect, a CL spectroscopic tomography device includes an electron beam source which directs an electron beam at an object to yield an emission by the object. A detector detects the emission. A controller receives information from the detector related to the detected emission. The controller derives a two-dimensional (2D) CL map from the information related to the detected emission, and derives a three-dimensional (3D) CL tomogram from the 2D CL map. |
| FILED | Wednesday, April 22, 2015 |
| APPL NO | 15/305329 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/0073 (20130101) A61B 5/0075 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/2254 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10552152 | Beard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARM Limited (Cambridge, United Kingdom) |
| ASSIGNEE(S) | Arm Limited (Cambridge, United Kingdom) |
| INVENTOR(S) | Jonathan Curtis Beard (Austin, Texas); Wendy Elsasser (Austin, Texas); Eric Van Hensbergen (Austin, Texas); Stephan Diestelhorst (Austin, Texas) |
| ABSTRACT | A data processing apparatus, and method of operation thereof, for executing instructions. The apparatus includes one or more host processors, each having a first processing unit, and a multi-level memory system. One or more levels of the memory system are tightly coupled to a corresponding second processing unit. At least one of the host processors includes an instruction scheduler that routes instructions selectively to at least one of the first and second processing units, dependent upon the availability of the processing units and the location, within the memory system, of data to be used when executing the instructions. |
| FILED | Friday, May 27, 2016 |
| APPL NO | 15/166444 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3004 (20130101) Original (OR) Class G06F 9/3016 (20130101) G06F 9/3802 (20130101) G06F 12/084 (20130101) G06F 12/0811 (20130101) G06F 12/0875 (20130101) G06F 12/0897 (20130101) G06F 2212/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10552339 | Basu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Arkaprava Basu (Austin, Texas); Joseph L. Greathouse (Austin, Texas) |
| ABSTRACT | An operating system (OS) of a processing system having a plurality of processor cores determines a cost associated with different mechanisms for performing a translation lookaside buffer (TLB) shootdown in response to, for example, a virtual address being remapped to a new physical address, and selects a TLB shootdown mechanism to purge outdated or invalid address translations from the TLB based on the determined cost. In some embodiments, the OS selects an inter-processor interrupt (IPI) as the TLB shootdown mechanism if the cost associated with sending an IPI is less than a threshold cost. In some embodiments, the OS compares the cost of using an IPI as the TLB shootdown mechanism versus the cost of sending a hardware broadcast to all processor cores of the processing system as the shootdown mechanism and selects the shootdown mechanism having the lower cost. |
| FILED | Tuesday, June 12, 2018 |
| APPL NO | 16/005882 |
| ART UNIT | 2132 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4812 (20130101) G06F 12/1027 (20130101) Original (OR) Class G06F 2212/682 (20130101) G06F 2212/683 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553194 | Longo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Daniel Longo (Kansas City, Missouri); Russell Stewart (Kansas City, Missouri); Bryce Hullet (Kansas City, Missouri) |
| ABSTRACT | A portable sound-masking device for placing on a roll-up door having a number of horizontally-extending elements. The sound-masking device has a fixture, a magnet, and a transducer. The fixture has an inner face, an outer face, and a pair of spaced-apart tabs protruding from the inner face, the tabs being configured to engage one of the horizontally-extending elements of the roll-up door. The magnet is fastened to the inner face of the fixture and provides a force that tethers the sound-masking device to the roll-up door. The transducer is fastened to the outer face and is configured to emit sound-masking noise. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/208628 |
| ART UNIT | 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/175 (20130101) Original (OR) Class Secret Communication; Jamming of Communication H04K 3/82 (20130101) H04K 2203/12 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 2201/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553697 | Armstrong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Andrew Armstrong (Albuquerque, New Mexico); Albert G. Baca (Albuquerque, New Mexico); Andrew A. Allerman (Tijeras, New Mexico); Carlos Anthony Sanchez (Belen, New Mexico); Erica Ann Douglas (Albuquerque, New Mexico); Robert Kaplar (Albuquerque, New Mexico) |
| ABSTRACT | Methods are provided for fabricating a HEMT (high-electron-mobility transistor) that involve sequential epitaxial growth of III-nitride channel and barrier layers, followed by epitaxial regrowth of further III-nitride material through a window in a mask layer. The regrowth takes place on the barrier layer, only in the access region or regions. Devices made according to the disclosed methods are also provided. |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 16/385193 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/18 (20130101) H01L 21/182 (20130101) H01L 21/0254 (20130101) H01L 21/0262 (20130101) H01L 21/746 (20130101) H01L 21/2036 (20130101) H01L 21/2056 (20130101) H01L 21/02642 (20130101) H01L 21/30621 (20130101) H01L 29/778 (20130101) H01L 29/7781 (20130101) H01L 29/7782 (20130101) H01L 29/7786 (20130101) H01L 29/66431 (20130101) Original (OR) Class H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553782 | Ketterson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Qorvo US, Inc. (Greensboro, North Carolina) |
| ASSIGNEE(S) | Qorvo US, Inc. (Greensboro, North Carolina) |
| INVENTOR(S) | Andrew Arthur Ketterson (Dallas, Texas); Xing Gu (Allen, Texas); Yongjie Cui (Plano, Texas); Xing Chen (Plainfield, Illinois) |
| ABSTRACT | A passive magnetic device (PMD) has a base electrode, a multi-port signal structure (MPSS), and a substrate therebetween. The MPSS has a central plate residing in a second plane and at least two port tabs spaced apart from one another and extending from the central plate. The substrate has a central portion that defines a mesh structure between the base electrode and the central plate of the multi-port signal structure. A plurality of magnetic pillars are provided within the mesh structure, wherein each of the plurality of the magnetic pillars are spaced apart from one another and surrounded by a corresponding portion of the mesh structure. The PMD may provide a magnetically self-biased device that may be used as a radio frequency (RF) circulator, an RF isolator, and the like. |
| FILED | Wednesday, February 21, 2018 |
| APPL NO | 15/901142 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/015 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/36 (20130101) H01P 1/38 (20130101) Transmission H04B 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553866 | Shao-Horn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yang Shao-Horn (Cambridge, Massachusetts); Kevin May (Ancaster, Canada); Jin Suntivich (Bangkok, Thailand) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Yang Shao-Horn (Cambridge, Massachusetts); Kevin May (Ancaster, Canada); Jin Suntivich (Bangkok, Thailand) |
| ABSTRACT | The oxygen evolution reaction (OER)-catalyzing activity of transition metal perovskite oxide catalysts depends on the occupancy of the σ-bonding orbital of eg symmetry parentage of the active cation. Catalysts having preferred values of eg orbital filling can have a high intrinsic activity for catalysis of the OER. |
| FILED | Tuesday, July 19, 2011 |
| APPL NO | 13/185939 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/0463 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/485 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553871 | Masarapu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Charan Masarapu (Fremont, California); Haixia Deng (Fremont, California); Yongbong Han (San Francisco, California); Yogesh Kumar Anguchamy (Newark, California); Subramanian Venkatachalam (Pleasanton, California); Sujeet Kumar (Newark, California); Herman A. Lopez (Sunnyvale, California) |
| ASSIGNEE(S) | Zenlabs Energy, Inc. (Fremont, California) |
| INVENTOR(S) | Charan Masarapu (Fremont, California); Haixia Deng (Fremont, California); Yongbong Han (San Francisco, California); Yogesh Kumar Anguchamy (Newark, California); Subramanian Venkatachalam (Pleasanton, California); Sujeet Kumar (Newark, California); Herman A. Lopez (Sunnyvale, California) |
| ABSTRACT | Improved high energy capacity designs for lithium ion batteries are described that take advantage of the properties of high specific capacity anode active compositions and high specific capacity cathode active compositions. In particular, specific electrode designs provide for achieving very high energy densities. Furthermore, the complex behavior of the active materials is used advantageously in a radical electrode balancing design that significantly reduced wasted electrode capacity in either electrode when cycling under realistic conditions of moderate to high discharge rates and/or over a reduced depth of discharge. |
| FILED | Friday, May 04, 2012 |
| APPL NO | 13/464034 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/024 (20130101) H01M 2/1646 (20130101) H01M 4/38 (20130101) H01M 4/131 (20130101) H01M 4/134 (20130101) H01M 4/386 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/582 (20130101) Original (OR) Class H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 10/446 (20130101) H01M 10/0525 (20130101) H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553874 | Elam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Jeffrey W. Elam (Elmhurst, Illinois); Lin Chen (Westmont, Illinois) |
| ABSTRACT | A hybrid protective coating includes an inorganic component and an organic component such that the inorganic component includes at least one of a metal oxide, a metal fluoride, or combination thereof, and the organic component includes at least one metalcone. |
| FILED | Friday, August 04, 2017 |
| APPL NO | 15/669771 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 7/50 (20130101) B05D 7/56 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/22 (20130101) C23C 16/40 (20130101) C23C 16/45527 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) H01M 4/382 (20130101) H01M 4/0423 (20130101) H01M 4/628 (20130101) Original (OR) Class H01M 4/1395 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553890 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Zhengcheng Zhang (Naperville, Illinois); Chi Cheung Su (Westmont, Illinois); Lei Cheng (Naperville, Illinois) |
| ABSTRACT | The present invention provides an aqueous redox flow battery comprising a negative electrode immersed in an aqueous liquid negative electrolyte, a positive electrode immersed in an aqueous liquid positive electrolyte, and a cation-permeable separator between the negative electrolyte from the positive electrolyte. During charging and discharging, the electrolytes are circulated over their respective electrodes. The electrolytes each comprise a redox reactant. Redox reactant of the positive electrolyte comprises a compound of Formula (I) as described in the specification. |
| FILED | Friday, June 23, 2017 |
| APPL NO | 15/631239 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/023 (20130101) H01M 8/188 (20130101) Original (OR) Class H01M 8/04753 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10554049 | Stewart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Emma Mary Stewart (Danville, California); Ciaran Martin Roberts (Berkeley, California); Emre can Kara (San Mateo, California); Michaelangelo David Tabone (Kensington, California) |
| ABSTRACT | Techniques are described for disaggregation of renewable energy generation on an electricity distribution system. Aggregate power measurements are identified a distribution substation. Active power load of the distribution substation and active power generated by renewable energy sites can be disaggregated from the aggregate power measurements. |
| FILED | Monday, March 20, 2017 |
| APPL NO | 15/463749 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/383 (20130101) Original (OR) Class H02J 3/386 (20130101) H02J 13/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10554151 | Post et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Richard F. Post (Walnut Creek, California); Edward G. Cook (Livermore, California) |
| ABSTRACT | A novel motor drive system has been described for use in electrostatic generator/motor systems based on the time variation of capacity of a rotating condenser comprised of segmented rotor and stator elements. It takes advantage of the fact that the motor action of such a system depends only on the rms value of the drive pulses, which therefore can be formed simply by periodically interrupting a high-frequency ac wave train. This new circuitry simplifies the drive system and takes advantage of recent developments of devices used in the art of inversion of dc voltages to high-frequency (tens of kiloHz) ac. |
| FILED | Wednesday, October 10, 2018 |
| APPL NO | 16/157022 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 1/004 (20130101) H02N 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10554172 | Deceglie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Michael Gardner Deceglie (Golden, Colorado); Timothy J. Silverman (Golden, Colorado) |
| ABSTRACT | The present disclosure relates to a method that includes applying a first condition to a photovoltaic (PV) device, and applying a second condition to the PV device, where the first condition results in a first luminescing of a surface of the PV device at a first intensity, the second condition results in a second luminescing of the surface at a second intensity, measuring the first intensity using a detector to create a first representation of the surface, measuring the second intensity using the detector to create a second representation of the surface, and comparing the first representation with the second representation to create a third representation of the surface that identifies a defect in the surface, if present. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/916862 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/66 (20130101) G01N 21/9501 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 50/15 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10548319 | Gokel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | George W. Gokel (Chesterfield, Missouri); Mohit B. Patel (St. Louis, Missouri) |
| ABSTRACT | The disclosure provides a method for increasing the lateral root development of a plant by exposing said plant to a composition containing a synthetic amphiphile. By increasing the number of lateral roots, the surface area of the root structure is increased, making the plants better able to survive such stresses as drought or low nutrients. |
| FILED | Friday, August 07, 2015 |
| APPL NO | 15/502449 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/72 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548519 | Arias et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ana Claudia Arias (Berkeley, California); Claire Lochner (Berkeley, California); Adrien Pierre (Berkeley, California); Yasser Khan (Berkeley, California) |
| ABSTRACT | Pulse oximeter devices include a first light emitting element that emits red light, a second light emitting element that emits green light or IR light; and a sensor element that detects red and green (or IR) light and that outputs signals representing detected red and green (or IR) light. The pulse oximeter device further includes a flexible substrate, wherein the first light emitting element, the second light emitting element and the sensor element are formed on the flexible substrate. The sensor element is configured to detect the emitted red and green light transmitted through tissue containing blood, and in certain aspects, the sensor element is configured to detect the emitted red and green (or IR) light reflected by tissue containing blood. A signal processing element (e.g., a processor) receives and processes the signals representing detected red and green (or IR) light output by the sensor element to produce signals representing blood oxygenation content. |
| FILED | Tuesday, January 24, 2017 |
| APPL NO | 15/414397 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/024 (20130101) A61B 5/0205 (20130101) A61B 5/6815 (20130101) A61B 5/6826 (20130101) A61B 5/14552 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548564 | Mauldin, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rivanna Medical LLC (Charlottesville, Virginia) |
| ASSIGNEE(S) | Rivanna Medical, LLC (Charlottesville, Virginia) |
| INVENTOR(S) | Frank William Mauldin, Jr. (Charlottesville, Virginia); Kevin Owen (Crozet, Virginia) |
| ABSTRACT | Systems and methods for processing ultrasound data are provided. The disclosure includes using at least one computer hardware processor to perform obtaining ultrasound data generated based, at least in part, on one or more ultrasound signals from an imaged region of a subject, the ultrasound data comprising fundamental frequency ultrasound data and harmonic frequency ultrasound data, calculating shadow intensity data based at least in part on the harmonic frequency ultrasound data, generating, based at least in part on the fundamental frequency ultrasound data, an indication of bone presence in the imaged region, generating, based at least in part on the shadow intensity data, an indication of tissue presence in the imaged region, and generating an ultrasound image of the subject at least in part by combining the indication of bone presence and the indication of tissue presence. |
| FILED | Tuesday, February 16, 2016 |
| APPL NO | 15/044425 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/461 (20130101) A61B 8/0875 (20130101) Original (OR) Class A61B 8/4254 (20130101) A61B 8/5207 (20130101) A61B 8/5223 (20130101) A61B 8/5269 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548628 | Swaney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Philip J. Swaney (Nashville, Tennessee); Robert J. Webster, III (Nashville, Tennessee) |
| ABSTRACT | A steerable surgical needle (10) includes an elongated needle shaft (12), a beveled tip portion (14), and a flexural element (16) that connects the needle shaft (12) with the tip portion (14) and permits the tip portion to deflect relative to the needle shaft. A method for steering the surgical needle (10) through tissue includes the steps of advancing the needle in the body tissue to induce tip flexure which causes the needle to follow a curved trajectory, and rotating the needle about its longitudinal axis in place, without advancement, to remove the tip flexure. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/208508 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3403 (20130101) Original (OR) Class A61B 17/3417 (20130101) A61B 2017/003 (20130101) A61B 2017/3454 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10548630 | Swaney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Philip J. Swaney (Nashville, Tennessee); Ray Lathrop (Nashville, Tennessee); Jessica Burgner (Hannover, Germany); Kyle Weaver (Thompson Station, Tennessee); Hunter B. Gilbert (Nashville, Tennessee); Robert J. Webster (Nashville, Tennessee); David B. Comber (Nashville, Tennessee) |
| ABSTRACT | The present invention relates to a system and apparatus for implementing a method for identifying tube parameters of a curved tube of an active cannula for operating on a target in a patient. The method includes the step (a) of acquiring a model of the patient anatomy including the target. The method also includes the step (b) of selecting a set of parameters characterizing a curved tube. The method also includes the step (c) of computing a workspace for an active cannula having the selected curved tube parameters. The method also includes the step (d) of comparing the workspace to the anatomical model to determine the degree to which an active cannula having the selected curved tube parameters covers the target. The method also includes the step (e) of repeating steps (b) through (d) through a defined number of curved tube parameter sets. The method also includes the step (f) of identifying the curved tube parameters that provide an active cannula with an optimal degree of target coverage. |
| FILED | Tuesday, February 11, 2014 |
| APPL NO | 14/177864 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3421 (20130101) Original (OR) Class A61B 2017/3443 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549255 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Yongsong Huang (Barrington, Rhode Island); Jose C. Aponte (Silver Spring, Maryland); Rafael Tarozo (Providence, Rhode Island); James Dillon (Pawtucket, Rhode Island) |
| ABSTRACT | Methods, compositions, devices and kits having a novel chromatographic material are provided herein for separating and identifying organic molecules and compounds, for example molecules and compounds containing electron rich functional groups such as carbon-carbon double bonds. The methods, compositions, and kits include a metal-thiolate chromatographic medium (MTCM) with a sulfur-containing functional group or a metal-selenolate chromatographic medium (MSCM) comprising a selenium-containing functional group covalently attached to a support medium, such that the sulfur-containing functional group or selenium-containing functional group is bound to at least one metal atom. The MTCM and/or MSCM has affinity and specificity to compounds having one or more carbon-carbon double bonds, and performs a highly efficient and rapid separation of samples yielding non-overlapping peaks of purified materials compared to traditional media. |
| FILED | Wednesday, February 06, 2013 |
| APPL NO | 13/760497 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/10 (20130101) B01D 15/38 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/0233 (20130101) B01J 20/0262 (20130101) Original (OR) Class B01J 20/283 (20130101) B01J 20/284 (20130101) B01J 20/285 (20130101) B01J 20/287 (20130101) B01J 20/3242 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549270 | Kanatzidis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Mercouri G. Kanatzidis (Wilmette, Illinois); Debajit Sarma (Chicago, Illinois); Emmanouil Manos (Evanston, Illinois) |
| ABSTRACT | Composite ion-exchange materials for use in an ion-exchange column are provided. Also provided are ion-exchange columns packed with the materials and methods for using the materials to remove metal ions from samples, such as waste water samples. The composite ion-exchange materials comprise a composite material comprising a metal chalcogenide and an alginate, wherein the composite material is mixed with a granular material. |
| FILED | Thursday, November 20, 2014 |
| APPL NO | 14/548952 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/361 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 39/02 (20130101) Original (OR) Class B01J 39/09 (20170101) B01J 47/018 (20170101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/42 (20130101) C02F 1/288 (20130101) C02F 2001/425 (20130101) C02F 2101/006 (20130101) C02F 2101/20 (20130101) C02F 2103/10 (20130101) C02F 2103/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549483 | Turner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Kevin Turner (Wayne, Pennsylvania); Helen Minsky (Philadelphia, Pennsylvania) |
| ABSTRACT | A structured composite surface includes a backing layer and a plurality of composite posts in contact with the backing layer, each composite post having a core made of a first material and an outer shell made of a second material, the outer shell is in contact with and surrounding the core, the core has a Young's modulus of at least 50 times greater than the outer shell. A method of transfer printing includes pressing a stamp including at least one composite post to a substrate, the at least one composite post having a core made of a first material and an outer shell made of a second material, the outer shell is in contact with and surrounding the core, the core has a Young's modulus at least 50 times greater than the outer shell, and retracting the stamp from the substrate by applying a shear load to the stamp. |
| FILED | Thursday, May 28, 2015 |
| APPL NO | 15/311536 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) B05D 3/007 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/48 (20130101) Original (OR) Class Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/756 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) G03F 7/20 (20130101) G03F 7/26 (20130101) G03F 7/162 (20130101) G03F 7/0385 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549504 | Baer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eric Baer (Cleveland Heights, Ohio); Anne Hiltner (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Eric Baer (Cleveland Heights, Ohio); Anne Hiltner (Cleveland, Ohio) |
| ABSTRACT | A multilayer film includes an extruded first polymer layer confined between extruded second polymer layers. The first polymer layer includes a high aspect ratio crystalline lamellae. The multilayer film is substantially impermeable to gas diffusion. |
| FILED | Monday, December 07, 2009 |
| APPL NO | 12/631964 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/02 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/265 (20150115) Y10T 428/31544 (20150401) Y10T 428/31725 (20150401) Y10T 428/31786 (20150401) Y10T 428/31938 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550003 | Hersam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Xiaolong Liu (Evanston, Illinois) |
| ABSTRACT | Articles comprising a boron allotrope and an organic compound having a lateral interface one with the other, together with method(s) of preparation of such articles. |
| FILED | Thursday, February 08, 2018 |
| APPL NO | 15/892124 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/04 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/20 (20130101) C01P 2002/60 (20130101) C01P 2004/90 (20130101) C01P 2006/40 (20130101) C01P 2006/90 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/04 (20130101) C23C 16/22 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0011 (20130101) H01L 51/0053 (20130101) H01L 51/0096 (20130101) H01L 2251/301 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550291 | Hardin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hitachi Chemical Co., Ltd. (Tokyo, Japan) |
| ASSIGNEE(S) | Hitachi Chemical Co., Ltd. (Tokyo, Japan) |
| INVENTOR(S) | Brian E. Hardin (San Carlos, California); Stephen T. Connor (San Francisco, California); Craig H. Peters (Belmont, California) |
| ABSTRACT | Oxidation-resistant electrically-conductive metal particles (ORCMP) are disclosed. ORCMPs are comprised of a base-metal core, an oxidation-resistant first shell, and an optional conductive second shell. ORCMPs are low cost alternatives to silver particles in metal fillers for low-temperature, electrically-conductive adhesives. Adhesives including ORCMPs, organic vehicles, and optional conductive metal particles such as silver were formulated to yield conductive films upon curing at low temperatures. Such films can be used in many electronic devices where low-temperature, low cost films are needed. |
| FILED | Monday, August 22, 2016 |
| APPL NO | 15/243847 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/06 (20130101) C08K 9/02 (20130101) C08K 2003/0806 (20130101) C08K 2003/2286 (20130101) C08K 2003/2293 (20130101) C08K 2201/001 (20130101) C08K 2201/003 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/10 (20180101) C09J 9/02 (20130101) Original (OR) Class C09J 11/04 (20130101) C09J 163/00 (20130101) C09J 2201/602 (20130101) C09J 2203/326 (20130101) C09J 2205/102 (20130101) C09J 2463/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550365 | Biggs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Manus J. P. Biggs (Galway, Ireland); Ryan Cooper (Oak Ridge, Tennessee); Jinyu Liao (New York, New York); Teresa Anne Fazio (Poughkeepsie, New York); Carl Fredrik Oskar Dahlberg (Stockholm, Sweden); Jeffrey William Kysar (New York, New York); Samuel Jonas Wind (White Plains, New York) |
| ABSTRACT | An elastomeric substrate comprises a surface with regions of heterogeneous rigidity, wherein the regions are formed by exposing the elastomeric substrate to an energy source to form the regions such that the regions include a rigidity pattern comprising spots. |
| FILED | Monday, April 10, 2017 |
| APPL NO | 15/483754 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) Original (OR) Class C12N 5/0663 (20130101) C12N 2533/30 (20130101) C12N 2535/00 (20130101) C12N 2535/10 (20130101) C12N 2537/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551313 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chenzhong Li (Miami, Florida); Maedeh Mozneb (Doral, Florida); Amirali Nilchian (Davie, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Chenzhong Li (Miami, Florida); Maedeh Mozneb (Doral, Florida); Amirali Nilchian (Davie, Florida) |
| ABSTRACT | Surface plasmon resonance (SPR) based sensing systems and methods for sensing rhythmic beating characteristics of living cells are provided. An SPR based sensing system can include: an SPR sensing surface capable of generating SPR upon stimulation by incident light and configured to sense contractions, expansions, and/or movements of a plurality of living cells on the SPR sensing surface; and a cell culture module for culturing the living cells on the SPR sensing surface. In addition, the SPR based sensing system can perform a real-time analysis of one or more analytes secreted from the living cells by including a coating on the SPR sensing surface. |
| FILED | Monday, April 15, 2019 |
| APPL NO | 16/383723 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/59 (20130101) Original (OR) Class G01N 33/4833 (20130101) G01N 2021/5903 (20130101) G01N 2201/0446 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551330 | Atre et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); STICHTING VOOR FUNDAMENTEEL ONDERZOEK DER MATERIE (Utrecht, Netherlands); Ashwin C. Atre (Stanford, California); Jennifer A. Dionne (Stanford, California); Benjamin Brenny (Utrecht, Netherlands); Toon Coenen (Utrecht, Netherlands); Albert Polman (Utrecht, Netherlands) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); STICHTING VOOR FUNDAMENTEEL ONDERZOEK DER MATERIE (Utrecht, Netherlands) |
| INVENTOR(S) | Ashwin C. Atre (Stanford, California); Jennifer A. Dionne (Stanford, California); Benjamin Brenny (Utrecht, Netherlands); Toon Coenen (Utrecht, Netherlands); Albert Polman (Utrecht, Netherlands) |
| ABSTRACT | In one aspect, a cathodoluminescence (CL) spectroscopic tomography device includes a sample stage to support a sample. An electron beam source scans an electron beam over the sample to yield light emission by the sample. A reflective element directs the light emission by the sample to a light detector. A controller controls operation of the sample stage, the electron beam source, and the light detector. In one aspect, a CL spectroscopic tomography device includes an electron beam source which directs an electron beam at an object to yield an emission by the object. A detector detects the emission. A controller receives information from the detector related to the detected emission. The controller derives a two-dimensional (2D) CL map from the information related to the detected emission, and derives a three-dimensional (3D) CL tomogram from the 2D CL map. |
| FILED | Wednesday, April 22, 2015 |
| APPL NO | 15/305329 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/0073 (20130101) A61B 5/0075 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/2254 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551744 | Hart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Anastasios John Hart (Waban, Massachusetts); Christopher Ryan Oliver (Commerce, Michigan); Adam Gregory Stevens (Midland, Michigan); Jieyuan Wu (Suzhou, China PRC); Chad Robert Archer (Midland, Michigan) |
| ABSTRACT | Systems, devices, and methods for printing on surfaces of three-dimensional objects are provided. The systems, devices, and methods allow for images, and three-dimensional structures, to be printed onto a surface of a three-dimensional object. The surface of the three-dimensional object can have many different shapes, including an arbitrary or non-uniform shape having multiple curves. In one exemplary embodiment, the method includes associating a pattern of polygons with a surface of a three-dimensional object and then scaling a pattern of polygons associated with an image to be printed onto the surface with the pattern of polygons associated with the surface. One or more polygons of the scaled pattern of polygons are then progressively projected onto the surface, and a photosensitive material associated with the surface is cured to set projected image portion on the surface. Systems, devices, and other methods for printing onto surfaces of three-dimensional objects are also provided. |
| FILED | Tuesday, May 28, 2019 |
| APPL NO | 16/423529 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/2051 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10551869 | Vrudhula et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sarma Vrudhula (Chandler, Arizona); Aykut Dengi (Tempe, Arizona); Niranjan Kulkarni (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Sarma Vrudhula (Chandler, Arizona); Aykut Dengi (Tempe, Arizona); Niranjan Kulkarni (Tempe, Arizona) |
| ABSTRACT | This disclosure relates generally to digital synchronous circuits that introduce clock skew without requiring clock buffers in a clock network. In one embodiment, the digital synchronous circuit includes a first flip flop and a second flip flop. The first flip flop is synchronized to be transparent and to be opaque in accordance with a first clock signal while the second flip flop is configured such that the second flip flop is synchronized to be transparent and to be opaque in accordance with a second clock signal. However, the second flip flop is configured to generate the first clock signal such that the second flip flop provides the first clock signal in a first clock state in response the second flip flop becoming transparent and provides the first clock signal in a second clock state in response the second flip flop becoming opaque thereby providing a clock skew without clock buffers. |
| FILED | Monday, February 27, 2017 |
| APPL NO | 15/443444 |
| ART UNIT | 2186 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/10 (20130101) G06F 1/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10552756 | Ipek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Engin Ipek (Rochester, New York); Ben Feinberg (Rochester, New York); Shibo Wang (Rochester, New York); Mahdi N. Bojnordi (Rochester, New York); Ravi Patel (Victor, New York); Eby G. Friedman (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Engin Ipek (Rochester, New York); Ben Feinberg (Rochester, New York); Shibo Wang (Rochester, New York); Mahdi N. Bojnordi (Rochester, New York); Ravi Patel (Victor, New York); Eby G. Friedman (Rochester, New York) |
| ABSTRACT | An energy efficient rapid single flux quantum (ERSFQ) logic register wheel includes a circular shift register having a plurality of destructive read out (DRO) cells. Each entry of the circular shift register includes a data block, a tag, and a valid bit. A compare and control logic is coupled to the circular shift register to compare a source specifier or a destination register specifier against a register tag stored in the wheel following each cycle of the register wheel. At least one or more read ports and at least one or more write ports are coupled to the circular shift register to write to or to read from a different entry each in the register wheel following each cycle of the register wheel. A RSFQ clearable FIFO with flushing and a crosspoint memory topology for integrating MRAM devices with ERSFQ circuits are also described. |
| FILED | Thursday, November 10, 2016 |
| APPL NO | 15/774503 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 7/381 (20130101) G06F 9/3004 (20130101) G06F 9/3016 (20130101) G06F 9/30105 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Static Stores G11C 11/44 (20130101) G11C 11/161 (20130101) G11C 11/1673 (20130101) G11C 11/1675 (20130101) G11C 19/32 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) H01L 27/222 (20130101) H01L 39/223 (20130101) H01L 43/02 (20130101) Pulse Technique H03K 19/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553711 | Lemaitre et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Maxime G. Lemaitre (Gainesville, Florida); Xiao Chen (Gainesville, Florida); Bo Liu (Gainesville, Florida); Mitchell Austin McCarthy (Gainesville, Florida); Andrew Gabriel Rinzler (Newberry, Florida) |
| ABSTRACT | Various aspects of tunable barrier transistors that can be used in high power electronics are provided. In one example, among others, a tunable barrier transistor includes an inorganic semiconducting layer; a source electrode including a nano-carbon film disposed on the inorganic semiconducting layer; a gate dielectric layer disposed on the nano-carbon film; and a gate electrode disposed on the gate dielectric layer over at least a portion of the nano-carbon film. The nano-carbon film can form a source-channel interface with the inorganic semiconducting layer. A gate field produced by the gate electrode can modulate a barrier height at the source-channel interface. The gate field may also modulate a barrier width at the source-channel interface. |
| FILED | Friday, April 24, 2015 |
| APPL NO | 15/305227 |
| ART UNIT | 2896 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/45 (20130101) H01L 29/517 (20130101) H01L 29/0673 (20130101) H01L 29/778 (20130101) Original (OR) Class H01L 29/1606 (20130101) H01L 51/0048 (20130101) H01L 51/0562 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553793 | Jha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Rashmi Jha (Wyoming, Ohio); Andrew Rush (Cincinnati, Ohio); Eric Herrmann (Beavercreek, Ohio) |
| ABSTRACT | Systems and methods of use and fabrication are described for a non-volatile resistive random access memory (RRAM) multi-terminal device including a first electrode, a second electrode, a metal oxide disposed between the first electrode and the second electrode, and an at least first gate configured to apply a voltage bias to change a resistive state in the metal oxide. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 16/367637 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 13/004 (20130101) G11C 13/0069 (20130101) G11C 2013/0045 (20130101) G11C 2013/0078 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/2436 (20130101) H01L 27/2463 (20130101) H01L 45/146 (20130101) Original (OR) Class H01L 45/1206 (20130101) H01L 45/1253 (20130101) H01L 45/1625 (20130101) H01L 45/1675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553875 | Greer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Julia R. Greer (San Marino, California); Lucas R. Meza (Pasadena, California); Lauren C. Montemayor (Pasadena, California); Xun W. Gu (Pasadena, California) |
| ABSTRACT | A scaffold includes struts that intersect at nodes. In some instances, a cross section of the cores has at least one dimension less than 100 microns. The core can be a solid, liquid or a gas. In some instances, one or more shell layers are positioned on the core. |
| FILED | Wednesday, April 16, 2014 |
| APPL NO | 14/254824 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/26 (20130101) H01G 11/30 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/72 (20130101) Original (OR) Class H01M 8/0247 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10554154 | Majidi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Carmel Majidi (Pittsburgh, Pennsylvania); Steven Collins (Pittsburgh, Pennsylvania); Stuart Diller (Pittsburgh, Pennsylvania) |
| ABSTRACT | An electrostatic clutch is described comprising a plurality of micron-scale thickness electrodes, adjacent electrodes being separated by a thin film of dielectric material. A power source and controller apply a voltage across two electrodes, causing an electrostatic force to develop. When engaged, a force can be transferred through the clutch. A tensioning device maintains the alignment of the clutch when the electrodes are disengaged, but permits movement in at least one direction. In some embodiments, multiple clutches are connected to an output to provide variable force control and a broad range of torque input and output values. Moreover, the clutch can be used as an energy-recycling actuator that captures mechanical energy from negative work movements, and returns energy during positive work movements. |
| FILED | Tuesday, July 16, 2019 |
| APPL NO | 16/513593 |
| ART UNIT | 3655 — Material and Article Handling |
| CURRENT CPC | Couplings for Transmitting Rotation; Clutches; Brakes F16D 27/00 (20130101) F16D 28/00 (20130101) Electric Machines Not Otherwise Provided for H02N 13/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10554458 | Ibrahim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHEASTERN UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | NORTHEASTERN UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Mahmoud Ayman Ahmed Ibrahim (Boston, Massachusetts); Marvin Onabajo (Jamaica Plain, Massachusetts) |
| ABSTRACT | Techniques and architectures for providing FSK signal modulation using mixing for the generation of the two output frequencies are described. In an embodiment, a frequency-shift keying (FSK) transmitter may be operative to provide transmission of wireless signals. The FSK transmitter may include a high-frequency generator to generate at least one high-frequency wave signal based on a fixed frequency signal, a low-frequency generator to generate at least one low-frequency wave signal based on the fixed frequency signal, and at least one mixer to mix the at least one high-frequency wave signal and the at least one low-frequency wave signal to generate a logic signal, the logic signal comprising one of a logic 0 signal or a logic 1 signal based on digital input data. |
| FILED | Wednesday, April 04, 2018 |
| APPL NO | 15/945452 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Modulation H03C 3/09 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/38 (20130101) Pulse Technique H03K 5/00006 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/16 (20130101) H03L 7/0992 (20130101) Transmission H04B 1/04 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10549255 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Yongsong Huang (Barrington, Rhode Island); Jose C. Aponte (Silver Spring, Maryland); Rafael Tarozo (Providence, Rhode Island); James Dillon (Pawtucket, Rhode Island) |
| ABSTRACT | Methods, compositions, devices and kits having a novel chromatographic material are provided herein for separating and identifying organic molecules and compounds, for example molecules and compounds containing electron rich functional groups such as carbon-carbon double bonds. The methods, compositions, and kits include a metal-thiolate chromatographic medium (MTCM) with a sulfur-containing functional group or a metal-selenolate chromatographic medium (MSCM) comprising a selenium-containing functional group covalently attached to a support medium, such that the sulfur-containing functional group or selenium-containing functional group is bound to at least one metal atom. The MTCM and/or MSCM has affinity and specificity to compounds having one or more carbon-carbon double bonds, and performs a highly efficient and rapid separation of samples yielding non-overlapping peaks of purified materials compared to traditional media. |
| FILED | Wednesday, February 06, 2013 |
| APPL NO | 13/760497 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/10 (20130101) B01D 15/38 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/0233 (20130101) B01J 20/0262 (20130101) Original (OR) Class B01J 20/283 (20130101) B01J 20/284 (20130101) B01J 20/285 (20130101) B01J 20/287 (20130101) B01J 20/3242 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549516 | Palmieri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Frank L. Palmieri (Hampton, Virginia); John W. Connell (Yorktown, Virginia); Christopher J. Wohl, Jr. (Portsmouth, Virginia) |
| ABSTRACT | A method for bonding composite substrates includes coupling a first co-cure prepreg layer having a first off-set amine to epoxide molar ratio onto a surface of a first composite substrate and coupling a second co-cure prepreg layer having a second off-set amine to epoxide molar ratio onto a surface of a second composite substrate. The first and second composite substrates are cured to the first and second co-cure prepreg layers, respectively, using a first cure cycle (including B-stage and cure temperatures) to form a first and a second co-cure prepreg layer portion. The method further includes coupling the first co-cure prepreg layer portion to the second co-cure prepreg layer portion and applying a second cure cycle to cure the first co-cure prepreg layer portion of the first composite substrate to the second co-cure prepreg layer portion of the second composite substrate to form a monolithic covalently bonded composite structure. |
| FILED | Friday, September 08, 2017 |
| APPL NO | 15/699433 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/02 (20130101) B29C 65/14 (20130101) B29C 65/4835 (20130101) B29C 65/5014 (20130101) B29C 65/5057 (20130101) B29C 66/43 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/0242 (20130101) B29C 66/721 (20130101) B29C 66/919 (20130101) B29C 66/1122 (20130101) B29C 66/73752 (20130101) B29C 66/73754 (20130101) B29C 66/73941 (20130101) B29C 66/81455 (20130101) B29C 66/91445 (20130101) B29C 66/91921 (20130101) B29C 70/30 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/022 (20130101) B32B 5/024 (20130101) B32B 5/026 (20130101) B32B 5/26 (20130101) B32B 7/12 (20130101) B32B 27/08 (20130101) B32B 27/12 (20130101) B32B 27/18 (20130101) B32B 27/20 (20130101) B32B 27/26 (20130101) B32B 27/34 (20130101) B32B 27/36 (20130101) B32B 27/38 (20130101) Original (OR) Class B32B 27/40 (20130101) B32B 27/42 (20130101) B32B 27/281 (20130101) B32B 37/14 (20130101) B32B 2250/04 (20130101) B32B 2260/023 (20130101) B32B 2260/046 (20130101) B32B 2262/10 (20130101) B32B 2262/14 (20130101) B32B 2262/105 (20130101) B32B 2262/106 (20130101) B32B 2262/0253 (20130101) B32B 2262/0261 (20130101) B32B 2262/0269 (20130101) B32B 2262/0276 (20130101) B32B 2264/10 (20130101) B32B 2264/102 (20130101) B32B 2264/104 (20130101) B32B 2270/00 (20130101) B32B 2305/72 (20130101) B32B 2305/74 (20130101) B32B 2305/076 (20130101) B32B 2305/77 (20130101) B32B 2307/536 (20130101) B32B 2307/558 (20130101) B32B 2309/02 (20130101) B32B 2605/18 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 5/06 (20130101) C09J 2463/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10549845 | Epstein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Alan H. Epstein (Lexington, Massachusetts); Gabriel L. Suciu (Glastonbury, Connecticut); Jesse M. Chandler (South Windsor, Connecticut) |
| ABSTRACT | A propulsion system for an aircraft including at least two main gas turbine engines and a plurality of dedicated boundary layer ingestion fans. The propulsion system is arranged such that a combined thrust produced by the boundary layer ingestion fans is less than 20 percent of a total thrust of the main engines and the boundary layer ingestion fans. The boundary layer ingestion fans are controllable and selectively turned off at lower speeds. |
| FILED | Friday, May 26, 2017 |
| APPL NO | 15/606051 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/0009 (20130101) B64C 21/06 (20130101) Original (OR) Class B64C 23/02 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 2033/0226 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10552651 | Fink et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of the National Aeronautics and Space (Washington, District of Columbia) |
| INVENTOR(S) | Patrick W. Fink (Missouri City, Texas); Gregory Y. Lin (Friendswood, Texas); Timothy F. Kennedy (Sugar Land, Texas); Phong H. Ngo (Friendswood, Texas) |
| ABSTRACT | A radio frequency identification (RFID) system for frequency multiplexing includes, in an exemplary embodiment, an RFID interrogator configured for generating an RFID signal, wherein a channel frequency of the RFID signal changes over time; at least one antenna or transmission line; and a diplexer coupling the RFID interrogator and the antennas or transmission lines and configured for distributing the RFID signal to each of the antennas or transmission lines, respectively, depending on the channel frequency of the RFID signal generated. The antennas or transmission lines are configured to transmit an electromagnetic wave in response to and at the channel frequency of the RFID signal distributed thereto. Other embodiments include RFID systems and methods including a frequency selective surface and both similar and different components and aspects for frequency multiplexing. |
| FILED | Wednesday, June 28, 2017 |
| APPL NO | 15/635843 |
| ART UNIT | 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10356 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 15/0013 (20130101) Transmission H04B 1/713 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10548322 | Dhingra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | Washington State University (Pullman, Washington) |
| INVENTOR(S) | Amit Dhingra (Pullman, Washington); Christopher Hendrickson (Pullman, Washington); Seanna Hewitt (Pullman, Washington) |
| ABSTRACT | Methods of controlling the maturation of plants and/or plant products (e.g. fruit, vegetable, ornamentals, etc.) by manipulating Alternative Oxidase (AOX) activity. An increase in activity hastens the maturation process while a decrease in activity slows or stops maturation. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 15/456330 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 3/00 (20130101) A01N 59/02 (20130101) Original (OR) Class Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 7/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10550353 | Catchmark et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Jeffrey Catchmark (University Park, Pennsylvania); Kai Chi (University Park, Pennsylvania) |
| ABSTRACT | Multi-surfactant systems where two or more surfactant molecules are coupled to control the spatial distribution of polar groups of the combined surfactant molecules are disclosed. The system can be implemented by an aqueous medium including an associate charge constant surfactant and charge variable surfactant. The charge variable surfactant has at least one neutral end group at one pH value of the medium and at least one either an anionic polar group or a cationic polar group at a different pH value of the medium. The charge constant surfactant has at least one, and preferably two or more groups that does not change charge at the one or different pH values of the aqueous medium. The multi-surfactant system can be coupled or connected to the surface of a substrate where the arrangement of the two or more coupled surfactant molecules control the polarity of the substrate surface. |
| FILED | Friday, May 20, 2016 |
| APPL NO | 15/572129 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Detergent Compositions; Use of Single Substances as Detergents; Soap or Soap-making; Resin Soaps; Recovery of Glycerol C11D 1/04 (20130101) Original (OR) Class C11D 1/40 (20130101) C11D 1/50 (20130101) C11D 1/52 (20130101) C11D 1/83 (20130101) C11D 1/86 (20130101) C11D 1/835 (20130101) C11D 3/222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10552300 | Kuhn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | D. Richard Kuhn (Columbia, Maryland); Raghu N. Kacker (North Potomac, Maryland) |
| ABSTRACT | A process for testing a program includes: receiving a variable comprising a plurality of input values; producing a plurality of equivalence classes for the input values; producing a representative value per equivalence class; producing, by a processor, a primary covering array comprising a plurality of primary vectors; producing a secondary covering array comprising a plurality of secondary vectors; providing the secondary vectors to the program; and producing a result vector comprising a plurality of result entries to test the program. A computer system for testing the program includes: a memory; and a processor, in communication with the memory, wherein the computer system is configured to perform the process for testing the program. A computer program product for testing the program includes: a non-transitory computer readable storage medium readable by a processor and storing program code for execution by the processor to perform the process. |
| FILED | Tuesday, February 09, 2016 |
| APPL NO | 15/019448 |
| ART UNIT | 2191 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3676 (20130101) Original (OR) Class G06F 11/3692 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553897 | Udovic |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNEMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Terrence John Udovic (Washington, District of Columbia) |
| ABSTRACT | A process for making a superionic conducting salt includes: combining a primary salt and an impact member, the primary salt including an ordered phase and being an ionic conductor; impacting the primary salt with the impact member; and converting the primary salt to the superionic conducting salt in response to impacting the primary salt with the impact member at a conversion temperature to make the superionic conducting salt, the conversion temperature optionally being less than a thermally activated transition temperature that thermally converts the primary salt to the superionic conducting salt in an absence of the impacting the primary salt, and the superionic conducting salt including a superionic conductive phase in a solid state at less than the thermally activated transition temperature. |
| FILED | Friday, June 03, 2016 |
| APPL NO | 15/172641 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/026 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10553093 | Fry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Mark A. Fry (Atlantic City, New Jersey); Barry T. Smith (Atlantic City, New Jersey) |
| ABSTRACT | A security system to detect motions and/or features associated with a traveler, the security system includes a camera configured to capture an image series of the traveler in an Eulerian or Lagrangian frame of reference, wherein the captured image series contains motions and features associated with the traveler; an alarm system configured to produce an alert signal; and an electronic control unit. The electronic control unit is configured to magnify the motions and features associated with the traveler to generate frame of reference perceptible motions and features, detect characteristic kinematic behaviors of the perceptible motions and features, measure characteristic kinematic quantities of the characteristic kinematic behaviors, determine the presence of features that deviate from a threshold value for the characteristic kinematic quantities, and activate the alarm system to produce the alert signal. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/260801 |
| ART UNIT | 2482 — Recording and Compression |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00771 (20130101) Image Data Processing or Generation, in General G06T 5/20 (20130101) G06T 7/20 (20130101) G06T 7/70 (20170101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 13/19697 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 7/183 (20130101) H04N 7/188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10553128 | Mounts, Jr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Jack B. Mounts, Jr. (Glynco, Georgia) |
| ABSTRACT | A water rollover simulation system includes a simulation training device. The simulation training device is connected to a track, wherein one end of the track is submerged in water. The simulation training device begins a simulation on another portion of the track not submerged in water, moves toward the end of the track, and completes the simulation by allowing one or more trainees to escape the simulation training device while the simulation training device is submerged under water. The water rollover simulation system includes various safety features. The safety features can be activated automatically after a predetermined amount of time, or manually via a remote control system. |
| FILED | Tuesday, March 15, 2016 |
| APPL NO | 15/070662 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 9/00 (20130101) G09B 9/02 (20130101) G09B 9/003 (20130101) G09B 9/06 (20130101) Original (OR) Class G09B 9/042 (20130101) G09B 9/052 (20130101) G09B 9/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 10550395 | Xiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yi Xiao (Miami, Florida); Haixiang Yu (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Yi Xiao (Miami, Florida); Haixiang Yu (Miami, Florida) |
| ABSTRACT | The subject invention provides methods, assays and products for detecting small-molecules in a sample, in particular, in both clinical and field settings. The method for detecting a small-molecule target in a sample comprises providing a sample, contacting the sample with an aptamer-based sensor selective for the small-molecule target, and sensitively and rapidly detecting the small-molecule target in the sample. Specifically, the method utilizes EATR-amplified small-molecule sensors based on cooperative binding split aptamers (CBSAs). |
| FILED | Friday, April 06, 2018 |
| APPL NO | 15/947315 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/946 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10548860 | Nicolls et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Board Of Trustees of The Leland Stanford Junior University (Stanford, California); The United States Government as Represented By The Department Of Veterans Affairs (Washington, District of Columbia); The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Mark R. Nicolls (Palo Alto, California); Jayakumar Rajadas (Cupertino, California); Geoffrey C. Gurtner (Woodside, California); Xinguo Jiang (Palo Alto, California); Gundeep Dhillon (Stanford, California); Gregg L. Semenza (Reisterstown, Maryland) |
| ABSTRACT | Formulations and methods are provided for improving the function, i.e. clinical outcome, of solid organ transplants. Lung transplantation is of particular interest. In the methods of the invention, a nanoparticle formulation comprising an effective dose of an iron chelator active agent in nanoparticle form, including without limitation, deferoxamine (DFO), deferasirox (DFX), and deferiprone (DFP), etc. suspended in a carrier compatible with the tissue of interest, is topically applied to the surface of tissues at the site of anastomosis. The nanoparticles are comprised of the active agent and a pharmaceutically acceptable stabilizer. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/260989 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 9/5138 (20130101) A61K 9/5146 (20130101) A61K 9/5161 (20130101) A61K 9/5169 (20130101) A61K 31/164 (20130101) Original (OR) Class A61K 31/436 (20130101) A61K 31/4196 (20130101) A61K 31/4412 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10552749 | Riabov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Anton Viktorovich Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (Port Chester, New York); Octavian Udrea (Ossining, New York) |
| ABSTRACT | A mechanism is provided for computing a solution to a plan recognition problem. The plan recognition problem includes the model and a partially ordered sequence of observations or traces. The plan recognition is transformed into an AI planning problem such that a planner can be used to compute a solution to it. The approach is general. It addresses unreliable observations: missing observations, noisy observations (or observations that need to be discarded), and ambiguous observations). The approach does not require plan libraries or a possible set of goals. A planner can find either one solution to the resulting planning problem or multiple ranked solutions, which maps to the most plausible solution to the original problem. |
| FILED | Tuesday, December 08, 2015 |
| APPL NO | 14/962714 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10550441 | Petropoulos |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MONOGRAM BIOSCIENCES, INC. (South San Francisco, California) |
| ASSIGNEE(S) | Monogram BioSciences, Inc. (South San Francisco, California) |
| INVENTOR(S) | Christos J. Petropoulos (Half Moon Bay, California) |
| ABSTRACT | The invention provides a method for determining whether a human immunodeficiency virus is resistance to a viral entry inhibitor. The methods are particularly useful for determining resistance to inhibitors that act by a non-competitive mechanism. In certain aspects, the methods comprise determining whether an HIV population is resistant to an HIV entry inhibitor, comprising determining a log-sigmoid inhibition curve comprising data points for entry of the HIV population in the presence of varying concentrations of the HIV entry inhibitor, wherein if the entry of the HIV population cannot be completely inhibited by the HIV entry inhibitor, the HIV population is resistant to the HIV entry inhibitor. |
| FILED | Monday, December 09, 2013 |
| APPL NO | 14/100467 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10553871 | Masarapu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charan Masarapu (Fremont, California); Haixia Deng (Fremont, California); Yongbong Han (San Francisco, California); Yogesh Kumar Anguchamy (Newark, California); Subramanian Venkatachalam (Pleasanton, California); Sujeet Kumar (Newark, California); Herman A. Lopez (Sunnyvale, California) |
| ASSIGNEE(S) | Zenlabs Energy, Inc. (Fremont, California) |
| INVENTOR(S) | Charan Masarapu (Fremont, California); Haixia Deng (Fremont, California); Yongbong Han (San Francisco, California); Yogesh Kumar Anguchamy (Newark, California); Subramanian Venkatachalam (Pleasanton, California); Sujeet Kumar (Newark, California); Herman A. Lopez (Sunnyvale, California) |
| ABSTRACT | Improved high energy capacity designs for lithium ion batteries are described that take advantage of the properties of high specific capacity anode active compositions and high specific capacity cathode active compositions. In particular, specific electrode designs provide for achieving very high energy densities. Furthermore, the complex behavior of the active materials is used advantageously in a radical electrode balancing design that significantly reduced wasted electrode capacity in either electrode when cycling under realistic conditions of moderate to high discharge rates and/or over a reduced depth of discharge. |
| FILED | Friday, May 04, 2012 |
| APPL NO | 13/464034 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/024 (20130101) H01M 2/1646 (20130101) H01M 4/38 (20130101) H01M 4/131 (20130101) H01M 4/134 (20130101) H01M 4/386 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/582 (20130101) Original (OR) Class H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 10/446 (20130101) H01M 10/0525 (20130101) H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10549319 | Dearing et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Unites States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Stephen M. Dearing (Oak Hill, Virginia); Carla F. Sherry (Annandale, Virginia) |
| ABSTRACT | Methods, systems and devices for item processing. The systems can include a PASS module that can include features that receive inputs relating to an item for processing and provide those inputs to other components and/or modules of a PASS system and/or of another system. The PASS system can include a variety of modules, including the PASS module, and can collect information and/or inputs from the variety of modules of the PASS system and use that information in item processing. The methods of item processing can use the PASS system and the PASS module to perform a variety of functions including, for example, revenue protection, sorting of items, task management, sampling and data collection, redirecting if enroute items, and personnel management. |
| FILED | Tuesday, September 25, 2018 |
| APPL NO | 16/141839 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 7/005 (20130101) Original (OR) Class B07C 2301/0058 (20130101) Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus G07B 2017/00443 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10553020 | Hainline et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Ratheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Allen Hainline (Rowlett, Texas); Richard W. Ely (Lewisville, Texas) |
| ABSTRACT | A method can include determining, based on elevation data of a geographic region corresponding to a location at which an image was captured and a solar elevation angle at a time the image was captured, whether each pixel of the image is a shadow or a non-shadow to create a shadow mask of the image, generating an eroded shadow mask that includes the shadow mask with a specified number of pixels from a perimeter of each shadow in the shadow mask changed to respective values corresponding to non-shadows, generating a dilated shadow mask that includes the specified number of pixels in the shadow mask changed to values corresponding to shadows, and refining the shadow mask using the eroded shadow mask and the dilated shadow mask to create a refined shadow mask. |
| FILED | Tuesday, March 20, 2018 |
| APPL NO | 15/926285 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 15/60 (20130101) Original (OR) Class G06T 17/05 (20130101) G06T 2215/12 (20130101) G06T 2215/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 04, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200204.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page