FedInvent™ Patents
Patent Details for Tuesday, February 11, 2020
This page was updated on Monday, March 27, 2023 at 06:01 AM GMT
Department of Health and Human Services (HHS)
| US 10555721 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Yilei Li (Palo Alto, California); Steven Chu (Menlo Park, California) |
| ABSTRACT | Nonlinear ultrasound imaging systems and methods are disclose. In one aspect, a nonlinear ultrasound imaging system includes a first transducer configured to transmit a first ultrasound signal along a scan line, a second transducer configured to sweep a second ultrasound signal along the scan line such that the first and second ultrasound signals intersect at a plurality of voxels, and a third transducer configured to receive echoes associated with interactions of the first and second ultrasound signals at the plurality of voxels. The nonlinear ultrasound imaging system further includes a processor configured to generate an ultrasound image based on the echoes. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 15/990530 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/06 (20130101) A61B 8/14 (20130101) Original (OR) Class A61B 8/481 (20130101) A61B 8/488 (20130101) A61B 8/4488 (20130101) A61B 8/4494 (20130101) A61B 8/5207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555791 | Krishnaswamy et al. |
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| FUNDED BY |
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| APPLICANT(S) | CairnSurgical, Inc. (Lebanon, New Hampshire) |
| ASSIGNEE(S) | CairnSurgical, Inc. (Lebanon, New Hampshire) |
| INVENTOR(S) | Venkataramanan Krishnaswamy (Lebanon, New Hampshire); Robert F. Rioux (Ashland, Massachusetts); David Danielsen (Westborough, Massachusetts); George Bourne (Boston, Massachusetts) |
| ABSTRACT | The present disclosure includes customized guidance devices in the form of guidance templates configured to fit over a given area of a patient's body and provide guidance during a tissue treatment or tissue removal procedure of that given area, which may include administration of an agent to a target tissue, target tissue biopsy, target tissue resection, or target tissue ablation. The customized guidance templates are generally constructed via an additive manufacturing process (i.e., three-dimensional (3D) printing) or subtractive manufacturing process (i.e., milling) based on a fabrication instruction file, which may include imaging data of the given area of the patient's body in which targeted tissue treatment is to be performed. The fabrication instruction file may further include additional data, such as the type of procedure to be performed (i.e., biopsy of the tissue abnormality, destruction or resection of the tissue abnormality, etc.). |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 16/437915 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/0233 (20130101) A61B 17/3403 (20130101) A61B 34/20 (20160201) A61B 90/17 (20160201) Original (OR) Class A61B 2017/00796 (20130101) A61B 2017/3405 (20130101) A61B 2034/107 (20160201) A61B 2090/3908 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555911 | Zhou et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Jiangbing Zhou (Cheshire, Connecticut); Toral R. Patel (Bloomfield, Connecticut); Joseph M. Piepmeier (Woodbridge, Connecticut); William Mark Saltzman (New Haven, Connecticut) |
| ABSTRACT | Brain-penetrating polymeric nanoparticles that can be loaded with drugs and are optimized for intracranial convection-enhanced delivery (CED) have been developed. In the preferred embodiment, these are loaded with FDA-approved compounds, identified through library screening to target brain cancer stem cells (BSCSs). The particles are formed by emulsifying a polymer-drug solution, then removing solvent and centrifuging at a first force to remove the larger particles, then collecting the smaller particles using a second higher force to sediment the smaller particles having a diameter of less than 100 nm, more preferably less than 90 nanometers average diameter, able to penetrate brain interstitial spaces. |
| FILED | Monday, May 06, 2013 |
| APPL NO | 14/397830 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 9/0085 (20130101) A61K 9/513 (20130101) Original (OR) Class A61K 9/5153 (20130101) A61K 31/17 (20130101) A61K 31/337 (20130101) A61K 31/428 (20130101) A61K 31/495 (20130101) A61K 31/4745 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555916 | Katz |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | David M. Katz (Shaker Heights, Ohio) |
| ABSTRACT | A method of treating a pervasive development disorder in a subject includes administering to the subject an amount of an NMDAR antagonist effective to ameliorate biochemical and functional abnormalities in the subject associated with loss-of-function mutations of the gene encoding methyl-CpG binding protein 2 (MeCP2). |
| FILED | Monday, January 27, 2014 |
| APPL NO | 14/763750 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/135 (20130101) Original (OR) Class A61K 31/165 (20130101) A61K 31/166 (20130101) A61K 31/453 (20130101) A61K 31/498 (20130101) A61K 31/5365 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555919 | Farez et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hopsital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Mauricio Farez (Buenos Aires, Argentina); Francisco J. Quintana (Jamaica Plain, Massachusetts); Jorge Correale (Buenos Aires, Argentina) |
| ABSTRACT | Methods for treating, or reducing risk of developing, seasonal worsening of multiple sclerosis (MS) in a subject who has MS, comprising administering a melatonin agonist to a subject. |
| FILED | Thursday, November 12, 2015 |
| APPL NO | 15/525375 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) Original (OR) Class A61K 31/343 (20130101) A61K 31/4045 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 209/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555942 | Tang et al. |
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| FUNDED BY |
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| APPLICANT(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida); THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida); The Johns Hopkins University (Baltimore, Maryland); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Hengli Tang (Tallahassee, Florida); Emily M. Lee (Tallahassee, Florida); Anil Mathew Tharappel (Tallahassee, Florida); Hongjun Song (Baltimore, Maryland); Guo-Li Ming (Baltimore, Maryland); Wei Zheng (Rockville, Maryland); Miao Xu (Rockville, Maryland); Shu Yang (Rockville, Maryland); Ruili Huang (Rockville, Maryland); Wenwei Huang (Rockville, Maryland); Khalida Shamim (Gaithersburg, Maryland); Hao Li (Rockville, Maryland) |
| ABSTRACT | The present invention concerns the use of emetine compounds for the treatment or prevention of Flavivirus infections, such as Zika virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as Zika virus infection, by administering an emetine compound such as emetine or cephaeline, or a combination of two or more emetine compounds, to a subject in need thereof; methods for inhibiting Flavivirus infections such as Zika virus infections in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits for treating or preventing Flavivirus infections, such Zika virus infections. |
| FILED | Wednesday, October 10, 2018 |
| APPL NO | 16/156124 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555948 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rhode Island Hospital (Providence, Rhode Island) |
| ASSIGNEE(S) | Rhode Island Hospital (Providence, Rhode Island) |
| INVENTOR(S) | Qian Chen (Barrington, Rhode Island); Yupeng Chen (Mansfield, Massachusetts); Hongchuan Yu (Mansfield, Massachusetts); Michael G. Ehrlich (Providence, Rhode Island) |
| ABSTRACT | The compositions and methods of the invention provide compositions and methods for preferential targeting of tissues to delivery therapeutic or diagnostic agents. For example, such compounds are useful in the treatment of joint disorders those affecting articulating joints, e.g., injury-induced osteoarthritis as well as autoimmune diseases affecting joint tissue such as rheumatoid arthritis. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/687289 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 9/0092 (20130101) A61K 9/5123 (20130101) A61K 9/5146 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 47/6949 (20170801) A61K 49/0095 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1137 (20130101) C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Enzymes C12Y 304/24812 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/102 (20130101) Technologies for Adaptation to Climate Change Y02A 50/401 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555957 | Subbaiah et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois, a body corporate and politic of the state of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of The University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Papasani V. Subbaiah (Chicago, Illinois); Poorna Yalagala (Chicago, Illinois); Sugasini Dhavamani (Chicago, Illinois) |
| ABSTRACT | Described herein are at least compounds and formulations that can be or contain a docosahexaenoic acid-lysophosphatidylcholine (DHA-LPC) and/or eicosapenteanoic acid-lysophosphatidylcholine (EPA-LPC). Also described herein are at least methods of making and using the compositions and formulations DHA-LPC and/or EPA-LPC. |
| FILED | Thursday, May 10, 2018 |
| APPL NO | 15/976481 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 31/661 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555961 | Molitoris et al. |
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| FUNDED BY |
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| APPLICANT(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana); United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana); UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Bruce A. Molitoris (Indianapolis, Indiana); Mark C. Wagner (Indianapolis, Indiana); Ruben M. Sandoval (Indianapolis, Indiana); Mark Gerard Goebl (Indianapolis, Indiana) |
| ABSTRACT | Various aspects relate to the use of C-1 gentamicin as an antibiotic effective for the treatment of a bacterial infection, a genetic disorder, or cancer in a subject. |
| FILED | Friday, June 03, 2016 |
| APPL NO | 15/579487 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/351 (20130101) A61K 31/7036 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555975 | Murray et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Joseph A. Murray (Rochester, Minnesota); Eric V. Marietta (Rochester, Minnesota); Susan H. Barton (Reston, Virginia); Veena Taneja (Rochester, Minnesota); Ashutosh Mangalam (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials related to Prevotella histicola preparations. For example, Prevotella histicola preparations in the form of an oral medicament or dietary supplement (e.g., a pill, tablet, capsule) are provided. In addition, methods and materials for using a Prevotella histicola preparation provided herein as an anti-inflammatory agent are provided. |
| FILED | Tuesday, September 26, 2017 |
| APPL NO | 15/715471 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/135 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 9/00 (20130101) A61K 9/0053 (20130101) A61K 35/74 (20130101) Original (OR) Class A61K 35/741 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555987 | Schally et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida); U.S.A., REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida); U.S.A., REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Andrew Schally (Miami Beach, Florida); Joshua M. Hare (Miami Beach, Florida); Norman Block (Hollywood, Florida); Samirah Gomes (Miami Beach, Florida); Rosemeire M. Kanashiro-Takeuchi (Miami, Florida) |
| ABSTRACT | Disclosed herein are compositions of GHRH agonists and peptides, and methods to treat disorders, such as ischemia and reperfusion injury. In one embodiment, a method of treating a reperfusion injury in a subject in need may involve administering a therapeutically effective amount of at least one GHRH agonist peptide to the subject. In additional embodiment, a method of promoting vasculogenesis in a mammal may involve administering a therapeutically effective amount of at least one GHRH agonist peptide to the subject. In a further embodiment, a method of promoting differentiation of mesenchymal stem cells into endothelial cells may involve contacting mesenchymal stem cells with at least one GHRH agonist peptide. |
| FILED | Tuesday, November 21, 2017 |
| APPL NO | 15/820079 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555989 | Hashimoto-Torii et al. |
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| APPLICANT(S) | Children's National Medical Center (Washington, District of Columbia) |
| ASSIGNEE(S) | Children's National Medical Center (Washington, District of Columbia) |
| INVENTOR(S) | Kazue Hashimoto-Torii (Bethesda, Maryland); Masaaki Torii (Bethesda, Maryland); Mohammad Shahid (Hyattsville, Maryland); Hiroki Morizono (Washington, District of Columbia) |
| ABSTRACT | Methods for treating learning disabilities associated with fetal alcohol syndrome and other neurological disorders by administering SK channel blockers, antagonists, inhibitors or modifiers like tamapin. |
| FILED | Thursday, October 13, 2016 |
| APPL NO | 15/767361 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0085 (20130101) A61K 38/1767 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555992 | Sun |
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| FUNDED BY |
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| APPLICANT(S) | Xingmin Sun (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Xingmin Sun (Tampa, Florida) |
| ABSTRACT | Described are immunogenic proteins against Clostridium difficile. Also described are compositions comprising the immunogenic proteins. Further described are methods of preventing or treating a Clostridium difficile infection in a subject in need thereof. |
| FILED | Wednesday, May 30, 2018 |
| APPL NO | 15/992497 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) A61K 39/08 (20130101) Original (OR) Class A61K 39/0275 (20130101) A61K 2039/6037 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 19/00 (20130101) C07K 2319/03 (20130101) C07K 2319/55 (20130101) C07K 2319/74 (20130101) Enzymes C12Y 204/00 (20130101) C12Y 304/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556001 | Jiang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The united States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Baoming Jiang (Atlanta, Georgia); Roger I. Glass (Atlanta, Georgia); Jean-Francois Saluzzo (La-Gaude, France) |
| ABSTRACT | Methods of thermally inactivating a rotavirus are provided according to the present invention which include exposing the rotavirus to a temperature in the range of about 50° C.-80° C., inclusive, for an incubation time sufficient to render the rotavirus incapable of replication or infection. The thermally inactivated rotavirus is antigenic and retains a substantially intact rotavirus particle structure. Vaccine compositions and methods of vaccinating a subject against rotavirus are provided which include generation and use of thermally inactivated rotavirus. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/725221 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/15 (20130101) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/5252 (20130101) A61K 2039/55505 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2720/12334 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556002 | Rao |
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| FUNDED BY |
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| APPLICANT(S) | The Catholic University of America (Washington, District of Columbia) |
| ASSIGNEE(S) | The Catholic University of America (Washington, District of Columbia) |
| INVENTOR(S) | Venigalla B. Rao (Silver Spring, Maryland) |
| ABSTRACT | Bivalent immunogenic compositions against anthrax and plague are disclosed herein. One bivalent immunogenic composition comprises a triple fusion protein containing three antigens, F1 and V from Yersinia pestis and PA antigen from Bacillus anthracia fused in-frame and retaining structural and functional integrity of all three antigens. Another bivalent immunogenic composition comprises bacteriophage nanoparticles arrayed with these three antigens on the capsid surface of the bacteriophage nanoparticles. These bivalent immunogenic compositions are able to elicit robust immune response in a subject administered said the bivalent immunogenic compositions and provide protection to the subject against sequential or simultaneous challenge with both anthrax and plague pathogens. |
| FILED | Friday, February 09, 2018 |
| APPL NO | 15/892772 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/07 (20130101) A61K 39/0291 (20130101) A61K 39/295 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 2039/57 (20130101) A61K 2039/70 (20130101) A61K 2039/627 (20130101) A61K 2039/645 (20130101) A61K 2039/5256 (20130101) A61K 2039/6075 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/005 (20130101) C07K 14/24 (20130101) C07K 14/32 (20130101) C07K 19/00 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2795/00034 (20130101) C12N 2795/00062 (20130101) C12N 2795/10122 (20130101) C12N 2795/10134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556017 | Hanes et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Justin Hanes (Baltimore, Maryland); Kannie Wai Yan Chan (Baltimore, Maryland); Michael T. McMahon (Columbia, Maryland); Ming Yang (Towson, Maryland); Tao Yu (Baltimore, Maryland) |
| ABSTRACT | Mucus-penetrating liposomal nanoparticles and methods of making and using thereof are described herein. The nanoparticles contain one or more lipids, one or more PEG-conjugated lipids, and optionally one or more additional materials that physically and/or chemically stabilize the particles. The nanoparticle have an average diameter of about 100 nm to about 300 nm, preferably from about 100 nm to about 250 nm, more preferably from about 100 nm to about 200 nm. The particles are mobile in mucus. The liposomes can further contain one or more therapeutic, prophylactic, and/or diagnostic agent to be delivered to a mucosal surface, such as the CV tract, the colon, the nose, the lungs, and/or the eyes. The liposomes can further contain one or more CEST agents to allow real time imaging of the particles in a live animal. The particles may also further contain an imaging agent, such as a fluorescent label. |
| FILED | Tuesday, February 06, 2018 |
| APPL NO | 15/890156 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 31/704 (20130101) A61K 47/6911 (20170801) Original (OR) Class A61K 49/1812 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/906 (20130101) Y10S 977/907 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556020 | Zamore et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Phillip D. Zamore (Northboro, Massachusetts); Jennifer Broderick (Worcester, Massachusetts) |
| ABSTRACT | The instant disclosure provides RNA-modulating agents that function to recruit one or more small regulatory RNA molecules (e.g., miRNA molecules, Y RNAs, and siRNAs) to a target mRNA thereby modulating (e.g., inhibiting) the translation of the target mRNA or destabilizing the mRNA. Also provided are miRNA inhibitors and diagnostic agents that have improved binding affinity for their target miRNAs. Methods for using the RNA-modulating agents, miRNA inhibitors and diagnostic agents are also provided. |
| FILED | Friday, September 25, 2015 |
| APPL NO | 14/866186 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) C12N 2320/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556021 | Lam et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Kit S. Lam (Davis, California); Juntao Luo (Sacramento, California) |
| ABSTRACT | The present invention provides a nanocarrier having an interior and an exterior, the nanocarrier comprising at least one conjugate, wherein each conjugate includes a polyethylene glycol (PEG) polymer. Each conjugate also includes at least two amphiphilic compounds having both a hydrophilic face and a hydrophobic face. In addition, each conjugate includes an oligomer, wherein at least 2 of the amphiphilic compounds are covalently attached to the oligomer which is covalently attached to the PEG. The nanocarrier is such that each conjugate self-assembles in an aqueous solvent to form the nanocarrier such that a hydrophobic pocket is formed in the interior of the nanocarrier by the orientation of the hydrophobic face of each amphiphilic compound towards each other, and wherein the PEG of each conjugate self-assembles on the exterior of the nanocarrier. |
| FILED | Monday, January 23, 2017 |
| APPL NO | 15/412912 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 9/5146 (20130101) A61K 49/0002 (20130101) Original (OR) Class A61K 49/0032 (20130101) A61K 49/0082 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556024 | Rashidian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mohammad Rashidian (Cambridge, Massachusetts); Hidde L. Ploegh (Boston, Massachusetts); Ralph Weissleder (Peabody, Massachusetts); Edmund J. Keliher (Topsfield, Massachusetts) |
| ABSTRACT | The present invention, in some aspects, provides methods, reagents, compositions, and kits for the radiolabeling of proteins, for example, of proteins useful for positron emission tomography (PET) or single-photon emission computed tomography (SPECT) (e.g., for diagnostic and therapeutic applications), using sortase-mediated transpeptidation reactions. Some aspects of this invention provide methods for the conjugation of an agent, for example, a radioactive agent or molecule to diagnostic or therapeutic peptides or proteins. Compositions comprising sortagged, radiolabeled proteins as well as reagents for generating radiolalebed proteins are also provided. Kits comprising reagents useful for the generation of radiolabeled proteins are provided, as are precursor proteins that comprise a sortase recognition motif. |
| FILED | Thursday, November 13, 2014 |
| APPL NO | 15/035924 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/1096 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 5/02 (20130101) Peptides C07K 16/2845 (20130101) C07K 2317/55 (20130101) C07K 2317/569 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/50 (20130101) Enzymes C12Y 304/2207 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 2333/95 (20130101) G01N 2800/52 (20130101) G01N 2800/7028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556113 | Villongco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents Of The University Of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Christopher T. Villongco (San Diego, California); Jeffrey H. Omens (San Diego, California); Andrew D. McCulloch (San Diego, California); David E. Krummen (Del Mar, California) |
| ABSTRACT | In some example embodiments, there may be provided a method. The method may include receiving three-dimensional image data representative of a heart; receiving electrical data representative of an electrophysiology of the heart; and generating, based on the received three-dimensional image data and the received electrical data, a computational model of the heart. Related systems and articles of manufacture may also be provided. |
| FILED | Friday, June 19, 2015 |
| APPL NO | 15/320644 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/04011 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/5247 (20130101) A61B 2576/023 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3627 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556856 | Uhrich et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Kathryn E. Uhrich (Riverside, California); Allison Faig (Madison, New Jersey) |
| ABSTRACT | The invention provides an antibacterial compound of formula I: or a salt thereof, as well as an antibacterial compound of formula II: or a salt thereof, wherein R1, R2, X, Y and n have any of the values defined in the specification. |
| FILED | Thursday, October 18, 2018 |
| APPL NO | 16/164517 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/42 (20130101) A61K 9/1272 (20130101) A61K 31/23 (20130101) A61K 31/23 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/005 (20130101) A61Q 19/10 (20130101) Acyclic or Carbocyclic Compounds C07C 233/47 (20130101) Original (OR) Class C07C 235/06 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) Technologies for Adaptation to Climate Change Y02A 50/401 (20180101) Y02A 50/473 (20180101) Y02A 50/475 (20180101) Y02A 50/478 (20180101) Y02A 50/481 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556860 | Hurley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS (Middleton, Wisconsin) |
| INVENTOR(S) | Laurence Hurley (Tucson, Arizona); Vijay Gokhale (Tucson, Arizona); HyunJin Kang (Tucson, Arizona); Kui Wu (Tucson, Arizona) |
| ABSTRACT | The present invention provides hTERT modulators and methods for producing and using the same. In particular, the present invention provide a compound of the formula as described herein. Some aspects of the invention are based on the characterization of the effect of hTERT core promoter region mutants on the 5-12 G-quadruplex structure and its stability. It is believed that some of the compounds of the invention bind selectively to the G-quadruplex in the hTERT core promoter mutant, which results in reversal of the effect of mutant promoter activation. |
| FILED | Wednesday, November 30, 2016 |
| APPL NO | 15/779132 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/505 (20130101) A61K 31/4402 (20130101) A61K 31/4995 (20130101) A61K 31/5377 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 275/54 (20130101) Original (OR) Class Heterocyclic Compounds C07D 219/08 (20130101) C07D 239/34 (20130101) C07D 239/52 (20130101) C07D 241/18 (20130101) C07D 295/088 (20130101) C07D 401/12 (20130101) C07D 403/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556873 | Chong |
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| FUNDED BY |
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| APPLICANT(S) | Hyun-Soon Chong (Chicago, Illinois) |
| ASSIGNEE(S) | ILLINOIS INSTITUTE OF TECHNOLOGY (Chicago, Illinois) |
| INVENTOR(S) | Hyun-Soon Chong (Chicago, Illinois) |
| ABSTRACT | Substituted 1,4,7-triazacyclononane-N,N′,N″-triacetic acid and 1,4,7,10-tetraazacycicododecane-N,N′,N″,N′″-tetraacetic acid compounds with a pendant amino or hydroxyl group, metal complexes thereof, compositions thereof, and methods of making and use in diagnostic imaging and treatment of cellular disorders. |
| FILED | Tuesday, August 25, 2015 |
| APPL NO | 14/834516 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/106 (20130101) Heterocyclic Compounds C07D 255/02 (20130101) Original (OR) Class C07D 413/12 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) C07F 5/00 (20130101) C07F 9/94 (20130101) Steroids C07J 43/003 (20130101) Peptides C07K 16/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556878 | Lin |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Hening Lin (Ithaca, New York) |
| ABSTRACT | A compound useful as a Sirt2 or Sirt5 inhibitor having the formula (1) wherein: R1 is a hydrocarbon group having at least two carbon atoms connected by carbon-carbon bonds, wherein said hydrocarbon group is optionally endcapped by a neutral or anionic oxygen-containing group; R2a, R2b, and R2c are independently selected from hydrogen atom and hydrocarbon groups; X0, X1, X2, and X3 are independently selected from —(CH2)n—, —NR5—, —O—, —S—, and a bond, wherein n represents 1, 2, or 3, provided that at least one of X0-X3 is —(CH2)n—; and R3 and R4 are independently selected from the group consisting of hydrogen atom, hydrocarbon groups, biological groups, and protecting groups. Also described are pharmaceutical compositions of the inhibiting compounds, and methods of treatment by administration of the inhibiting compounds. |
| FILED | Friday, June 06, 2014 |
| APPL NO | 14/896057 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 335/08 (20130101) Heterocyclic Compounds C07D 335/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556892 | Piomelli et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Fondazione Istituto Italiano Di Tecnologia (Genoa, Italy) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Fondazione Istituto Italiano di Technologia (Genoa, Italy) |
| INVENTOR(S) | Daniele Piomelli (Irvine, California); Rita Scarpelli (Rome, Italy); Marco Migliore (Genoa, Italy); Roger Heim (San Diego, California); Miguel Garcia-Guzmàn (San Diego, California) |
| ABSTRACT | Disclosed herein, inter alia, are compositions and methods for modulating the activity of N-acylethanolamine acid amidase for the treatment of a pathological state, including pain, an inflammatory condition, or a neurodegenerative disorder. |
| FILED | Tuesday, May 16, 2017 |
| APPL NO | 16/301200 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/28 (20180101) Heterocyclic Compounds C07D 413/04 (20130101) C07D 417/04 (20130101) Original (OR) Class C07D 417/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556893 | Panicker |
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| FUNDED BY |
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| APPLICANT(S) | ANGION BIOMEDICA CORP. (Uniondale, New York) |
| ASSIGNEE(S) | ANGION BIOMEDICA CORP. (Uniondale, New York) |
| INVENTOR(S) | Bijoy Panicker (Holtsville, New York) |
| ABSTRACT | The present invention provides compounds having the general structural formula (I) (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 15/989737 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/428 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 3/10 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 417/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556894 | Remiszewski et al. |
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| FUNDED BY |
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| APPLICANT(S) | FORGE Life Science, LLC (Doylestown, Pennsylvania) |
| ASSIGNEE(S) | Evrys Bio, LLC (Doylestown, Pennsylvania) |
| INVENTOR(S) | Stacy Remiszewski (Doylestown, Pennsylvania); Emre Koyuncu (Doylestown, Pennsylvania); Qun Sun (Princeton, Pennsylvania); Lillian Chiang (Princeton, New Jersey) |
| ABSTRACT | Novel compounds useful for treating and/or preventing HCMV infections are provided. |
| FILED | Monday, November 09, 2015 |
| APPL NO | 15/525504 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/427 (20130101) A61K 31/427 (20130101) A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 31/498 (20130101) A61K 31/498 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/4709 (20130101) A61K 31/4725 (20130101) A61K 31/4725 (20130101) A61K 31/5377 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 417/04 (20130101) C07D 417/06 (20130101) C07D 417/10 (20130101) C07D 417/14 (20130101) Original (OR) Class C07D 491/052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556916 | Sato et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Noriko Sato (Potomac, Maryland); Haitao Wu (Rockville, Maryland); Gary L. Griffiths (North Potomac, Maryland); Peter L. Choyke (Rockville, Maryland) |
| ABSTRACT | The invention provides a method of preparing a 89Zr-oxine complex of the formula. The invention also provides a method of labeling a cell with the 89Zr-oxine complex and a method for detecting a biological cell in a subject comprising administering the 89Zr-oxine complex to the subject. |
| FILED | Wednesday, April 01, 2015 |
| APPL NO | 15/300883 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0478 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/004 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/003 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 2458/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556920 | Vonnegut et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Chris Vonnegut (Springfield, Oregon); Airlia Shonkwiler (West Linn, Oregon); Michael Haley (Eugene, Oregon); Darren Johnson (Eugene, Oregon) |
| ABSTRACT | Disclosed embodiments concern a phosphorus-containing heterocyclic compound according to the formula One exemplary compound is Certain embodiments fluoresce with excitation by light. The compounds are useful as fluorescent probes and as bioisosteres. In some embodiments, the compounds are bioisosteres of alpha-quinolones. Also disclosed is a method for making the compounds. |
| FILED | Thursday, December 21, 2017 |
| APPL NO | 15/850388 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/395 (20130101) A61K 31/662 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/65846 (20130101) Original (OR) Class C07F 9/657172 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556929 | Philip |
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| FUNDED BY |
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| APPLICANT(S) | Emergex Vaccines Holdings Limited (Abingdon, Oxfordshire, United Kingdom) |
| ASSIGNEE(S) | Emergex Vaccines Holding Ltd. (Abingdon, Oxford, United Kingdom) |
| INVENTOR(S) | Ramila Philip (Ivyland, Pennsylvania) |
| ABSTRACT | Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHR) are significant global public health problems and understanding the overall immune response to infection will contribute to appropriate management of the disease and its potentially severe complications. Live attenuated and subunit vaccine candidates, which are under clinical evaluation, induce primarily an antibody response to the virus and minimal cross-reactive T cell responses. Currently, there are no available tools to assess protective T cell responses during infection or post vaccination. The present invention incorporates immunoproteomics to uncover novel HLA-A2 specific epitopes derived from Dengue Virus (DV)-infected cells. These epitopes are conserved with epitope-specific CTLs cross-reacting against all four DV serotypes. These epitopes have potential as new informational and diagnostic tools to characterize T cell immunity in Dengue virus (DV) infection, and serves as a universal vaccine candidate complementary to current vaccines. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/163162 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/017 (20130101) A61K 38/19 (20130101) A61K 39/12 (20130101) A61K 2039/55522 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/24134 (20130101) Technologies for Adaptation to Climate Change Y02A 50/386 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556932 | Herzog et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Roland W. Herzog (Gainesville, Florida); Henry Daniell (Media, Pennsylvania) |
| ABSTRACT | Protein replacement therapy for patients with hemophilia or other inherited protein deficiencies is often complicated by pathogenic antibody responses, including antibodies that neutralize the therapeutic protein or that predispose to potentially life-threatening anaphylactic reactions by formation of IgE. Using murine and canine hemophilia as a model, we have developed a prophylactic protocol against such responses that is non-invasive and does not include immune suppression or genetic manipulation of the patient's cells. Oral delivery of a coagulation factor expressed in chloroplasts, bioencapsulated in plant cells, effectively blocked formation of inhibitory antibodies in protein replacement therapy. Inhibitor titers were mostly undetectable and up to 100-fold lower in treated subjects when compared to controls. Moreover, this treatment eliminated fatal anaphylactic reactions that occurred after four to six exposures to intravenous coagulation factor protein. Finally, the method can effectively be used to reverse or reduce undesirable pre-existing inhibitor titers. |
| FILED | Tuesday, March 12, 2019 |
| APPL NO | 16/299928 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 36/00 (20130101) A61K 38/36 (20130101) A61K 38/37 (20130101) A61K 38/45 (20130101) A61K 38/47 (20130101) Peptides C07K 14/28 (20130101) Original (OR) Class C07K 14/755 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8214 (20130101) C12N 15/8257 (20130101) Enzymes C12Y 204/00 (20130101) C12Y 302/0102 (20130101) C12Y 302/01022 (20130101) Technologies for Adaptation to Climate Change Y02A 50/471 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556940 | Tran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Eric Tran (Portland, Oregon); Yong-Chen Lu (Rockville, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/758954 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/7051 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5748 (20130101) G01N 2333/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556943 | Knutson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); University of Washington (Seattle, Washington) |
| INVENTOR(S) | Keith L. Knutson (Jacksonville, Florida); Mary L. Disis (Renton, Washington); John D. Fikes (San Diego, California); Melanie Beebe (Apex, North Carolina); Glenn Ishioka (San Diego, California) |
| ABSTRACT | The present invention provides HLA-DR (MHC class II) binding peptides derived from the ovarian/breast cancer associated antigens, Human Epidermal Growth Factor Receptor 2 (HER-2/neu), Carcinoembryonic Antigen (CEA), Insulin Growth Factor Binding Protein 2 (IGFBP-2), and Cyclin D1. The immunogenic peptides can be used in cancer vaccines. |
| FILED | Friday, December 16, 2016 |
| APPL NO | 15/381454 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 2039/572 (20130101) Peptides C07K 7/08 (20130101) C07K 14/71 (20130101) Original (OR) Class C07K 14/4738 (20130101) C07K 14/4743 (20130101) C07K 14/4748 (20130101) C07K 14/70503 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556956 | Marasco |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Wayne A. Marasco (Wellesley, Massachusetts) |
| ABSTRACT | The present disclosure provides methods of modulating regulatory T-cell activity and function. |
| FILED | Wednesday, April 06, 2016 |
| APPL NO | 15/571202 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/39541 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2866 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/52 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557042 | Lynn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David M. Lynn (Middleton, Wisconsin); Uttam Manna (Guwahati, India) |
| ABSTRACT | The present invention provides polymer-based slippery liquid-infused porous surfaces (SLIPS) that can prevent adhesion and colonization by fungal and bacterial pathogens and also kill and/or attenuate the colonization and virulence of non-adherent pathogens in surrounding media. The present approach exploits the polymer and liquid oil phases in these slippery materials to sustain the release of small molecules such as a broad-spectrum antimicrobial agent, an antifungal agent, an antibacterial agent, an agent that modulates bacterial or fungal quorum sensing, an agent that attenuates virulence, or a combination thereof. This controlled release approach improves the inherent anti-fouling properties of SLIPS, has the potential to be general in scope, and expands the potential utility of slippery, non-fouling surfaces in both fundamental and applied contexts. |
| FILED | Tuesday, March 28, 2017 |
| APPL NO | 15/471628 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/73 (20130101) Heterocyclic Compounds C07D 235/28 (20130101) C07D 235/30 (20130101) C07D 307/12 (20130101) C07D 307/14 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) Original (OR) Class C09D 5/1625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557118 | Childs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the USA, as represented by the Secretary, Dept. of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services (Bethseda, Maryland) |
| INVENTOR(S) | Richard William Wyatt Childs (Rockville, Maryland); Yoshiyuki Takahashi (Showa-ku, Japan); Sachiko Kajigaya (Rockville, Maryland); Nanae Harashima (Rockville, Maryland) |
| ABSTRACT | Compositions and methods are provided for preventing or treating neoplastic disease in a mammalian subject. A composition is provided which comprises an enriched immune cell population reactive to a human endogenous retrovirus type E antigen on a tumor cell. A method of treating a neoplastic disease in a mammalian subject is provided which comprises administering to a mammalian subject a composition comprising an enriched immune cell population reactive to a human endogenous retrovirus type E antigen, in an amount effective to reduce or eliminate the neoplastic disease or to prevent its occurrence or recurrence. |
| FILED | Monday, January 07, 2019 |
| APPL NO | 16/241017 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/17 (20130101) A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/585 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) Original (OR) Class C12N 2740/10022 (20130101) C12N 2740/10034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557124 | Spence et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Jason Spence (Ann Arbor, Michigan); Briana Dye (Ann Arbor, Michigan) |
| ABSTRACT | The invention disclosed herein generally relates to methods and systems for converting stem cells into specific tissue(s) or organ(s) through directed differentiation. In particular, the invention disclosed herein relates to methods and systems for promoting definitive endoderm formation from pluripotent stem cells. The invention disclosed herein further relates to methods and systems for promoting ventral-anterior foregut spheroid tissue formation, 3-dimensional lung tissue formation, and lung organoid tissue formation produced in vitro from the described methods. |
| FILED | Thursday, April 21, 2016 |
| APPL NO | 15/134498 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0688 (20130101) Original (OR) Class C12N 2501/15 (20130101) C12N 2501/16 (20130101) C12N 2501/41 (20130101) C12N 2501/119 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2506/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557134 | Godfrey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts); ONTARIO INSTITUTE FOR CANCER RESEARCH MARS CENTRE (Toronto, Canada) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts); ONTARIO INSTITUTE FOR CANCER RESEARCH (Toronto, ON, Canada) |
| INVENTOR(S) | Tony Edward Godfrey (Chestnut Hill, Massachusetts); Anders Torbjoern Staahlberg (Kaallered, Sweden); Paul Krzyzanowski (Toronto, Canada) |
| ABSTRACT | Described herein are approaches for the improved detection, identification, and/or quantification of target nucleic acids. These approaches provide a means of detecting, identifying, and/or quantifying rare target nucleic acid molecules, including DNA and RNA molecules, from the same sample, and in the same reaction, by using “hairpin barcode primers,” as the term is defined herein, to incorporate unique barcodes into target nucleic acids in a PCR pre-amplification step. |
| FILED | Wednesday, February 24, 2016 |
| APPL NO | 15/552618 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6855 (20130101) C12Q 1/6874 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557145 | Martin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH (Ithaca, New York) |
| ASSIGNEE(S) | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (Ithaca, New York) |
| INVENTOR(S) | Gregory B. Martin (Ithaca, New York); Sarah R. Hind (Ithaca, New York); Susan R. Strickler (Ithaca, New York) |
| ABSTRACT | One aspect of the present invention relates to a nucleic acid construct that includes a nucleic acid molecule that encodes FLAGELLIN-SENSING 3 (“FLS3”) protein; a 5′ heterologous DNA promoter sequence; and a 3′ terminator sequence, where the nucleic acid molecule, the DNA promoter sequence, and the terminator sequence are operatively coupled to permit transcription of the nucleic acid molecule. The present invention also relates to a method of imparting disease resistance to a plant. This method involves transforming a plant or a plant seed with a nucleic acid molecule that increases expression of an FLS3 protein, where said transforming is effective in imparting disease resistance to the transformed plant or to a transgenic plant produced from the transformed plant seed. The present invention also relates to methods of expressing a nucleic acid molecule in a plant, identifying a candidate plant suitable for breeding that displays enhanced disease resistance, and enhancing efficiency of transformation of a plant by Agrobacterium. |
| FILED | Wednesday, July 08, 2015 |
| APPL NO | 15/324389 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) C12N 15/8279 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) C12Q 2600/13 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557691 | Stone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Giner, Inc. (Newton, Massachusetts) |
| ASSIGNEE(S) | GINER LIFE SCIENCES, INC. (Newton, Massachusetts) |
| INVENTOR(S) | Simon G. Stone (Arlington, Massachusetts); Linda A. Tempelman (Lincoln, Massachusetts); Melissa Schwenk (Waltham, Massachusetts) |
| ABSTRACT | Self-regulating electrolytic gas generator and implant system including the same. In one embodiment, the electrolytic gas generator is a water electrolyzer and includes a polymer electrolyte membrane with an anode on one side and a cathode on the other side. Anode and cathode seals surround the peripheries of the anode and cathode and include inlets for water and outlets for oxygen and hydrogen, respectively. A cathode current collector is placed in contact with the cathode, and an anode current collector, which may be an elastic, electrically-conductive diaphragm, is positioned proximate to the anode. The anode current collector is reversibly deformable between a first state in which it is in direct physical and electrical contact with the anode and a second state in which it distends, due to gas pressure generated at the anode, so that it is not in physical or electrical contact with the anode, causing electrolysis to cease. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 15/814124 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0075 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14276 (20130101) A61M 31/002 (20130101) A61M 2005/006 (20130101) A61M 2005/14204 (20130101) A61M 2202/0208 (20130101) A61M 2205/7536 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/04 (20130101) C25B 9/10 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557807 | Ros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Alexandra Ros (Phoenix, Arizona); Gerrit Brehm (Göttingen, Germany); Garrett Nelson (Mesa, Arizona); John Spence (Tempe, Arizona); Uwe Weierstall (Phoenix, Arizona); Austin Echelmeier (Tempe, Arizona) |
| ABSTRACT | A 3D printed hybrid nozzle device combining a microfluidic mixer with a liquid jet injector that addresses the bottleneck of investigating substrate-initiated biological reaction paths employing serial crystallography with XFELs. The hybrid nozzle provides for injecting aqueous protein crystal jets after fast mixing (<5 ms), reaching reaction time points (e.g., about 10 ms to about 150 ms) suitable to resolve enzyme kinetics. |
| FILED | Tuesday, May 22, 2018 |
| APPL NO | 16/328262 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/0062 (20130101) B01F 2215/0037 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2300/0867 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/2005 (20130101) Original (OR) Class G01N 23/20025 (20130101) G01N 2223/602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557847 | Weissleder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Ralph Weissleder (West Peabody, Massachusetts); Hakho Lee (Acton, Massachusetts); Hyungsoon Im (Peabody, Massachusetts); Cesar Castro (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed herein are compositions and methods for exosome detection with high sensitivity by using a nano-plasmonic sensor. The nano-plasmonic sensor comprises a plurality of nanoapertures suitable for transmission measurements. The detection sensitivity is on the order of 104-fold higher than western blotting and 102-fold higher than enzyme-linked immunosorbent assay (ELISA). A portable imaging system is also disclosed, enabling rapid and high-throughput detection of exosomes. The nano-plasmonic sensor and imaging system can be useful in diagnostics. |
| FILED | Tuesday, December 02, 2014 |
| APPL NO | 15/100997 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/553 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 33/57449 (20130101) G01N 2333/70596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557850 | Wicha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Max S. Wicha (Ann Arbor, Michigan); Christophe Ginestier (Marseilles, France) |
| ABSTRACT | The present invention provides methods of treating cancer by administering an IL8-CXCR1 pathway inhibitor (e.g., an anti-CXCR1 antibody or Repertaxin) alone or in combination with an additional chemotherapeutic agent such that non-tumorigenic and tumorigenic cancer cells in a subject are killed. The present invention also provides compositions and methods for detecting the presence of and isolating solid tumor stem cells in a patient (e.g., based on the presence of CXCR1 or FBXO21). |
| FILED | Wednesday, December 10, 2014 |
| APPL NO | 14/566436 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/337 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5743 (20130101) G01N 33/57407 (20130101) G01N 33/57415 (20130101) G01N 33/57434 (20130101) G01N 33/57449 (20130101) G01N 33/57492 (20130101) Original (OR) Class G01N 2333/7158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557856 | Singbartl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kai Singbartl (Pittsburgh, Pennsylvania); John A. Kellum, Jr. (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University Of Pittsburgh-Of The Commonwealth System Of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Kai Singbartl (Pittsburgh, Pennsylvania); John A. Kellum, Jr. (Pittsburgh, Pennsylvania) |
| ABSTRACT | This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, long-term dialysis. For example, prediction of long-term dialysis treatment can be determined by monitoring urine biomarkers related to the development of chronic kidney disease. For example, a normalized time course of approximately fourteen Days measuring hyaluronic acid, death receptor 5, and/or transforming growth factor β1 can be used to establish the risk of recovery versus non-recovery in patient's having suffered an acute kidney injury. |
| FILED | Friday, September 16, 2011 |
| APPL NO | 13/235005 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557857 | Beshay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OPTECH VENTURES, LLC (Torrance, California) |
| ASSIGNEE(S) | Intelligent Optical Systems, Inc. (Torrance, California) |
| INVENTOR(S) | Manal Beshay (Rancho Palos Verdes, California); Morgan Hatch (Long Beach, California) |
| ABSTRACT | Disclosed are embodiments of a lateral flow test strip (LFTS) platform which measure osteocalcin (OC) and deoxypyridinoline (Dpd) in saliva to identify early indications of bone loss and minimize bone fracture risk associated with osteoporosis. The OC assay embodiments are based on the experimentally identified optimal markers which exhibit selectivity with very low false positives, and sensitivity relevant to clinical requirements. A prospective clinical study sampling of 20 patients demonstrated excellent correlation of OC in saliva with bone mineral density (BMD). Salivary OC and Dpd levels were validated with a standard commercial ELISA kit against serum (OC) and urine (Dpd). |
| FILED | Wednesday, March 23, 2016 |
| APPL NO | 15/078519 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2333/47 (20130101) G01N 2333/78 (20130101) G01N 2333/916 (20130101) G01N 2800/108 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557859 | Wanner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Ina-Beate Wanner (Topanga, California); Joseph A. Loo (Encino, California) |
| ABSTRACT | A method for detection or monitoring status of traumatic brain injury (TBI) or spinal cord injury (SCI) in a subject is provided. In one embodiment, the method comprises contacting a specimen of bodily fluid obtained from the subject with reagents for assaying for a marker of TBI selected from aldolase C (ALDOC) and brain lipid binding protein (BLBP), or a trauma-specific break down product (BDP) of ALDOC or BLBP. The method further comprises measuring the amount of marker present in the specimen as compared to a control sample, and determining the presence of TBI or SCI when an elevated amount of marker is present in the specimen compared to the control sample. The method can comprises measuring the amount of glutamine synthetase (GS), astrocytic phosphoprotein PEA-15 (PEA15), αB-crystallin (CRYAB/HSP27), a cleavage product of ALDOC, GS, PEA15, or CRYAB, or a combination of two or more thereof. |
| FILED | Thursday, May 05, 2016 |
| APPL NO | 15/570982 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Enzymes C12Y 201/01259 (20150701) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/577 (20130101) G01N 33/6848 (20130101) G01N 33/6896 (20130101) Original (OR) Class G01N 2800/40 (20130101) G01N 2800/52 (20130101) G01N 2800/2871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557860 | Everett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Allen D. Everett (Glenwood, Maryland); Jun Yang (Baltimore, Maryland) |
| ABSTRACT | Methods and kits for determining, predicting, or diagnosing pulmonary artery hypertension (PAH) and for determining the efficacy of PAH therapy using biomarkers are provided. |
| FILED | Friday, August 21, 2015 |
| APPL NO | 15/505317 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) Original (OR) Class G01N 2333/4753 (20130101) G01N 2800/12 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557908 | Meyer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); Siemens Healthcare GmbH (Erlangen, Germany) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Craig H. Meyer (Charlottesville, Virginia); John P. Mugler, III (Charlottesville, Virginia); Samuel W. Fielden (Lewisburg, Pennsylvania); Gudrun Ruyters (Erlangen, Germany); Berthold Kiefer (Erlangen, Germany); Josef Pfeuffer (Erlangen, Germany) |
| ABSTRACT | In some aspects, the disclosed technology relates to magnetic field monitoring of spiral echo train imaging. In one embodiment, a method for spiral echo train imaging of an area of interest of a subject includes measuring k-space values and field dynamics corresponding to each echo of a spiral echo pulse train, using a dynamic field camera and a magnetic resonance imaging (MRI) system. The dynamic field camera is configured to measure characteristics of fields generated by the MRI system; the characteristics include at least one imperfection associated with the MRI system. The spiral echo pulse train corresponds to a spiral trajectory scan from the MRI system that obtains magnetic resonance imaging data using a pulse sequence which applies spiral gradients in-plane with through-plane phase encoding. The method also includes generating, based on the characteristics of the fields measured by the dynamic field camera and based on the obtained magnetic resonance imaging data, a model of the k-space trajectory corresponding to each echo of the spiral echo pulse train; and, based on the generated model of the k-space trajectory, reconstructing images that correspond to the area of interest and that are compensated for the at least one imperfection associated with the MRI system. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 15/947443 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4818 (20130101) G01R 33/5615 (20130101) Original (OR) Class G01R 33/56308 (20130101) G01R 33/56518 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559449 | Glaeser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Robert M. Glaeser (Berkeley, California); Bong-Gyoon Han (Castro Valley, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to arrangements including electron microscopy grids. In one aspect an arrangement includes an electron microscopy grid. The electron microscopy grid comprises a first surface and a second surface, with the first surface having a holey carbon film disposed thereon. A plurality of lipid molecules are disposed in a hole in the holey carbon film. Each lipid molecule of the plurality of lipid molecules has a hydrophilic head and a hydrophobic tail. A biotin-binding protein is attached to the hydrophilic heads of the plurality of lipid molecules. The biotin-binding protein is crystalline. |
| FILED | Monday, December 18, 2017 |
| APPL NO | 15/844854 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/20 (20130101) Original (OR) Class H01J 37/261 (20130101) H01J 2237/2007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559456 | Ouyang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Zheng Ouyang (West Lafayette, Indiana); Jiangjiang Liu (West Lafayette, Indiana); Yue Ren (West Lafayette, Indiana); Morgan McLuckey (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to systems and methods for analyzing an extracted sample using an immiscible extraction solvent. In certain embodiments, the invention provides a system for analyzing an analyte in a sample. The system includes an ionization probe and a mass spectrometer. The ionization probe includes a hollow body that optionally includes a distal tip. The hollow body is configured such that there is no substrate within the body and no electrode disposed on a surface of the body. An electrode is at least partially disposed within the hollow body. |
| FILED | Friday, January 30, 2015 |
| APPL NO | 15/113945 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/46 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/918 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/167 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10555697 | Obropta, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Edward W. Obropta, Jr. (Cape May Court House, New Jersey); Dava J. Newman (Marblehead, Massachusetts) |
| ABSTRACT | Described embodiments provide a system and method for measuring surface deformation and strain using digital image correlation of a surface of a test object. A data acquisition system acquires images of the surface. The surface has a unique surface pattern to facilitate image acquisition. The images are grouped into one or more image sets. Three dimensional image correlation is performed on each of the image sets to determine deformation and strain data. The deformation and strain data from the image sets are stitched into one dataset. Principal strains and lines of non-extension (LoNEs) directions are determined. One or more LoNEs streamlines and lines of maximum and minimum extensions are determined. Visualizations for the strain magnitudes, LoNE streamlines, maximum and minimum extension streamlines are generated in three dimensions. |
| FILED | Monday, October 05, 2015 |
| APPL NO | 15/514297 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Appliances or Methods for Making Clothes, e.g for Dress-making, for Tailoring, Not Otherwise Provided for A41H 1/00 (20130101) Diagnosis; Surgery; Identification A61B 5/0064 (20130101) A61B 5/0077 (20130101) A61B 5/442 (20130101) Original (OR) Class A61B 5/1121 (20130101) A61B 5/1127 (20130101) A61B 5/6828 (20130101) A61B 5/7225 (20130101) A61B 5/7278 (20130101) A61B 2562/0261 (20130101) A61B 2576/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556130 | Dolney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Derek Dolney (Huntingdon Valley, Pennsylvania); Robert Hollebeek (Berwyn, Pennsylvania) |
| ABSTRACT | A particle detection system for calibrating a particle therapy machine or validating a particle therapy plan. The detector system includes one or more two-dimensional particle detection layers for receiving a particle beam and one or more compensating layers. The compensating layer(s) are configured to adjust energy loss and scatter values introduced by the one or more two-dimensional particle detection layers to match water-equivalent values. Each compensation layer is positioned adjacent a respective one of the one or more two-dimensional particle detection layers. |
| FILED | Wednesday, July 08, 2015 |
| APPL NO | 15/324334 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1071 (20130101) A61N 5/1075 (20130101) Original (OR) Class A61N 2005/1076 (20130101) A61N 2005/1087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556707 | Taylor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joshua D. Taylor (Fredericksburg, Virginia); Jonathan U. Crook (King George, Virginia); John W. Gawalt (King George, Virginia); Jordan C. Lieberman (Fredericksburg, Virginia); Jessica L. Hildebrand (Fredericksburg, Virginia); Charles T. Miller (Fredericksburg, Virginia); Troy S. Newhart (King George, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Joshua D. Taylor (Fredericksburg, Virginia); Jonathan U. Crook (King George, Virginia); John W. Gawalt (King George, Virginia); Jordan C. Lieberman (Fredericksburg, Virginia); Jessica L. Hildebrand (Fredericksburg, Virginia); Charles T. Miller (Fredericksburg, Virginia); Troy S. Newhart (King George, Virginia) |
| ABSTRACT | A modular sensor platform is provided for installation on an unmanned aerial vehicle (UAV) for sensor operation. The platform includes an external shell that defines an internal volume, an interface module, and a mission module. The shell inserts between sections of the UAV. The interface module attaches to the shell within the volume. The mission module attaches to the shell within the volume. The interface module includes a communications package, a battery package and an air intake. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 15/813315 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/126 (20130101) B64C 2201/127 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 47/08 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0055 (20130101) G01N 33/0057 (20130101) G01N 33/0062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556803 | Wilcox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado School of Mines (Golden, Colorado) |
| ASSIGNEE(S) | Colorado School of Mines (Golden, Colorado) |
| INVENTOR(S) | Jennifer Wilcox (Golden, Colorado); Simona Liguori (Lakewood, Colorado) |
| ABSTRACT | The invention relates to a metallic membrane for nitrogen separation, the method of making the membrane and methods of using the membrane. The invention also relates to a metallic membrane for disassociation of nitrogen and subsequent reaction with hydrogen to produce ammonia at moderate conditions compared to a conventional Haber-Bosch process. |
| FILED | Monday, September 18, 2017 |
| APPL NO | 15/707007 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 69/02 (20130101) B01D 71/022 (20130101) B01D 2311/2696 (20130101) B01D 2325/10 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/2475 (20130101) B01J 35/065 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/0411 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556930 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University in St. Louis (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Fuzhong Zhang (St. Louis, Missouri); Wen Jiang (St. Louis, Missouri); Gayle Bentley (St. Louis, Missouri) |
| ABSTRACT | The present disclosure is generally related to transformed host cells and their use for the production of branched-chain acyl-ACPs, branched-chain acyl-ACP-derived chemicals and fuels, branched-chain fatty acids and producing branched-chain fatty acid-derived chemicals and fuels. More particularly, disclosed herein are transformed host cells and methods for producing branched-chain acyl-ACPs and branched-chain fatty acids in high titer and high percentages. Also disclosed are methods for producing specific branched-chain fatty acid species and producing branched-chain fatty acid-derived chemicals and fuels such as, for example, branched-chain alcohols and branched-chain fatty acid ethyl esters. |
| FILED | Friday, December 16, 2016 |
| APPL NO | 16/063497 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/245 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 15/70 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) C12P 7/6436 (20130101) C12P 21/02 (20130101) Enzymes C12Y 102/04004 (20130101) C12Y 203/01204 (20150701) C12Y 207/07063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556931 | Simon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raphael Simon (Baltimore, Maryland); Alan Cross (Chevy Chase, Maryland); Sharon Tennant (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Raphael Simon (Baltimore, Maryland); Alan Cross (Chevy Chase, Maryland); Sharon Tennant (Baltimore, Maryland) |
| ABSTRACT | The present invention is drawn to conjugates and vaccine compositions comprising a Pseudomonas flagellin or an antigenic fragment or derivative thereof linked to one or more Klebsiella surface polysaccharide antigens, such as Klebsiella pneumoniae O polysaccharide from serovars O1, O2a, O2a,c, O3, O4, O5, O7, O8 and O12. The present invention also provides serovar reagent strains to produce the conjugates and vaccine compositions and methods of inducing an immune response with the conjugates and vaccine compositions. |
| FILED | Thursday, December 14, 2017 |
| APPL NO | 15/842068 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/104 (20130101) A61K 39/0266 (20130101) A61K 47/61 (20170801) A61K 47/646 (20170801) A61K 2039/70 (20130101) Peptides C07K 14/21 (20130101) C07K 14/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557042 | Lynn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David M. Lynn (Middleton, Wisconsin); Uttam Manna (Guwahati, India) |
| ABSTRACT | The present invention provides polymer-based slippery liquid-infused porous surfaces (SLIPS) that can prevent adhesion and colonization by fungal and bacterial pathogens and also kill and/or attenuate the colonization and virulence of non-adherent pathogens in surrounding media. The present approach exploits the polymer and liquid oil phases in these slippery materials to sustain the release of small molecules such as a broad-spectrum antimicrobial agent, an antifungal agent, an antibacterial agent, an agent that modulates bacterial or fungal quorum sensing, an agent that attenuates virulence, or a combination thereof. This controlled release approach improves the inherent anti-fouling properties of SLIPS, has the potential to be general in scope, and expands the potential utility of slippery, non-fouling surfaces in both fundamental and applied contexts. |
| FILED | Tuesday, March 28, 2017 |
| APPL NO | 15/471628 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/73 (20130101) Heterocyclic Compounds C07D 235/28 (20130101) C07D 235/30 (20130101) C07D 307/12 (20130101) C07D 307/14 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) Original (OR) Class C09D 5/1625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557044 | Lynn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David Lynn (Middleton, Wisconsin); Uttam Manna (Madison, Wisconsin); Matthew Carter (Madison, Wisconsin) |
| ABSTRACT | This invention provides slippery liquid-infused porous surfaces (SLIPS) using nanoporous or microporous and chemically reactive polymer multilayers. This approach permits fabrication of slippery anti-fouling coatings on complex surfaces and provides new means to manipulate the mobilities of contacting aqueous fluids. The results expand the range of tools that can be used to manipulate the behaviors of SLIPS and open the door to new applications of this emerging class of soft materials. |
| FILED | Friday, June 24, 2016 |
| APPL NO | 15/192425 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1625 (20130101) Original (OR) Class C09D 5/1668 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557160 | Ellington et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Andrew D. Ellington (Austin, Texas); Ross Thyer (Austin, Texas) |
| ABSTRACT | Recombinant bacterial cells are provided that comprise a stable non-canonical amino acid translation pathway. In some aspects, the bacteria comprise nucleic acids encoding a non-canonical amino acid translation pathway (e.g., a tRNA for incorporation of a non-canonical amino acid, such selenocysteine); a marker polypeptide that includes the non-canonical amino acid. Recombinant tRNA and selection marker coding sequences are likewise provided. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 15/380560 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/86 (20130101) C12N 9/93 (20130101) C12N 15/11 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class Enzymes C12Y 305/02006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557367 | Blaney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Ken F. Blaney (Middleton, New Hampshire); Richard K. Hayford (Cape Neddick, Maine); Christopher M. Jarochym (Ogunquit, Maine) |
| ABSTRACT | An example active clearance control system for a gas turbine engine includes an actuator, and a case wall portion defining an aperture configured to receive the actuator. The actuator is configured to move an air seal segment, and the actuator is insertable to an installed position within the aperture through a radially outer side of the case wall portion. |
| FILED | Friday, December 19, 2014 |
| APPL NO | 15/105220 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/12 (20130101) F01D 11/20 (20130101) Original (OR) Class F01D 11/22 (20130101) F01D 25/24 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2270/64 (20130101) F05D 2270/65 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557368 | Blaney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Ken F. Blaney (Middleton, New Hampshire); Todd M. LaPierre (Middleton, New Hampshire) |
| ABSTRACT | An active clearance control system of a gas turbine engine includes a radially adjustable blade outer air seal system movable between a radially contracted Blade Outer Air Seal (BOAS) position that defines a first air volume and a radially expanded Blade Outer Air Seal (BOAS) position that defines a second air volume, the second air volume different than the first air volume. An accumulator system accommodate a difference in air volume between the first air volume and the second air volume. |
| FILED | Thursday, February 06, 2014 |
| APPL NO | 14/781179 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/22 (20130101) Original (OR) Class F01D 25/24 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/55 (20130101) F05D 2260/42 (20130101) F05D 2270/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557371 | Ruberte Sanchez |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Jose E. Ruberte Sanchez (Jupiter, Florida) |
| ABSTRACT | A variable vane assembly for a gas turbine engine includes a case having a bore and a recess. The case provides a first portion of a flow path surface. A vane includes a journal that extends along an axis from a vane end and received in the bore. An insert is arranged in the recess and provides a second portion of the flow path surface adjacent to the first flow path surface. The insert includes a pocket that slidably receives the vane end. The vane end is configured to move axially relative to the insert. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 15/649946 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/005 (20130101) F01D 17/162 (20130101) Original (OR) Class F01D 25/16 (20130101) Non-positive-displacement Pumps F04D 29/563 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/30 (20130101) F05D 2260/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557373 | Warren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Eli Cole Warren (Wethersfield, Connecticut); Kevin A Ford (Middletown, Connecticut) |
| ABSTRACT | A low profile embedded BTC probe may comprise a housing having a cavity disposed radially outward of a blade, a lower insulator disposed within the cavity, a sensor element disposed within the cavity, an upper insulator disposed within the cavity, a cap wherein the cap fills a remainder of the cavity, and a hard lead in electronic communication with the sensor element and the housing. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 15/832376 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 21/003 (20130101) Original (OR) Class Non-positive-displacement Pumps F04D 29/526 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/20 (20130101) F05D 2240/14 (20130101) F05D 2260/83 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 5/0014 (20130101) G01B 7/14 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 1/006 (20130101) G01H 11/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557550 | Saindon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mide Technology Corporation (Medford, Massachusetts) |
| ASSIGNEE(S) | Mide Technology Corporation (Woburn, Massachusetts) |
| INVENTOR(S) | Luke Clovis Saindon (Somerville, Massachusetts); Noel Jared Keegan (Medford, Massachusetts); Marthinus van Schoor (Arlington, Massachusetts) |
| ABSTRACT | A constant volume flexible joint system includes a flexible membrane for coupling across a joint and spaced radial support ribs fitted to the membrane. Axial support structures are coupled to the spaced radial support ribs preventing axial deformation of the joint due to a differential pressure. The axial support structure preferably include pivoting sockets and blocks enabling the joint to flex and the flexible membrane to contract on the inside of a bend and expand by an equal or near equal amount on the outside of the bend resulting in a constant volume joint that requires low or no torque throughout the bending motion. |
| FILED | Thursday, April 07, 2016 |
| APPL NO | 15/092851 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 11/10 (20130101) Pistons; Cylinders; Sealings F16J 3/048 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 403/453 (20150115) Y10T 403/32622 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557696 | Reuther et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | James J. Reuther (Worthington, Ohio); Paul E. Shawcross (Hilliard, Ohio); Chad M. Cucksey (Worthington, Ohio); Ronald L. Loeser (Bexley, Ohio); John R. Leach (Tucson, Arizona); Jason E. Paugh (Columbus, Ohio); Emmett Mark Tackett (West Jefferson, Ohio); James D. Gombarcik (Richwood, Ohio) |
| ABSTRACT | A self-glowing solid material comprises a man-made metal mixture containing at least one rare earth metal and an oxide of iron. The material is inducible by flame initiation to self-glow with yellow-to-red colors (577-to-700 nanometer wavelengths). A stealth tracer ammunition comprises a projectile body having a tip and a base, and a solid pellet disposed in the base. The pellet may be made from the above-mentioned self-glowing solid material or another suitable material. The pellet becomes incandescent as a result of being heated when the ammunition is fired. The incandescent pellet emits a glow observable only from behind when the ammunition travels downrange after being fired. An illuminant comprises a bimodal blend of a man-made metal mixture containing at least one rare earth metal and an oxide of iron. The bimodal blend is a blend of smaller-sized fragments and larger-sized pellets. The illuminant is capable of ignition and dispersion in response to ballistic energy to create illumination. An illumination device comprises a body having an interior cavity, the body configured to be launched as a projectile or configured to contain projectiles. An illuminant is disposed in the cavity, the illuminant comprising a bimodal blend of a suitable illuminant material. The illuminant is capable of ignition and dispersion in response to ballistic energy to create illumination. |
| FILED | Thursday, December 01, 2016 |
| APPL NO | 15/366269 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 23/008 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557705 | Kadambi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Achuta Kadambi (Los Angeles, California); Vage Taamazyan (Moscow, Russian Federation); Boxin Shi (Beijing, China PRC); Ramesh Raskar (Cambridge, Massachusetts) |
| ABSTRACT | A 3D imaging system uses a depth sensor to produce a coarse depth map, and then uses the coarse depth map as a constraint in order to correct ambiguous surface normals computed from polarization cues. The imaging system outputs an enhanced depth map that has a greater depth resolution than the coarse depth map. The enhanced depth map is also much more accurate than could be obtained from the depth sensor alone. In many cases, the imaging system extracts the polarization cues from three polarized images. Thus, in many implementations, the system takes only three extra images—in addition to data used to generate the coarse depth map—in order to dramatically enhance the coarse depth map. |
| FILED | Tuesday, February 19, 2019 |
| APPL NO | 16/278769 |
| ART UNIT | 2482 — Recording and Compression |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/24 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/507 (20170101) G06T 7/514 (20170101) G06T 2207/10028 (20130101) G06T 2207/10141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557793 | Barnes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright Patterson, AFB, Ohio) |
| INVENTOR(S) | Ronald A. Barnes (New Braunfels, Texas); Hope T. Beier (San Antonio, Texas); Bennett L. Ibey (San Antonio, Texas); Caleb C Roth (San Antonio, Texas); Joel N Bixler (San Antonio, Texas); Christopher M Valdez (San Antonio, Texas) |
| ABSTRACT | Variations in a translucent medium are imaged by detecting deflections and/or polarization shifts in a probe beam transmitted through the translucent medium. Deflections and polarization shifts may be detected using a first polarizing filter positioned between a probe beam generator and the translucent medium to polarize the probe beam in a first direction, a beam splitter positioned to receive the probe beam after it has been transmitted through the medium, and a probe beam deflection detector that receives a first split beam and provides a deflection signal associated with refractive index variations in the medium. A second polarizing filter receives a second split beam and polarizes it in a second direction, perpendicular to the first direction. An intensity sensor receives the second split beam, after it has passed through the second polarizing filter, and provides an intensity signal associated with a polarization shift in the medium. |
| FILED | Wednesday, August 08, 2018 |
| APPL NO | 16/058466 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 21/4133 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 21/006 (20130101) G02B 21/008 (20130101) G02B 21/0032 (20130101) G02B 21/0036 (20130101) G02B 21/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557818 | Gorodetsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alon Gorodetsky (Irvine, California); Long Phan (Irvine, California); Ward Walkup (Pasadena, California); David Ordinario (Irvine, California) |
| ABSTRACT | The disclosed invention relates to novel materials and associated methods for conducting protons, such materials comprising cephalopod proton-conducting proteins such as reflectins. The protonic conductivity of such cephalopod proton-conducting proteins may be modulated by the application of an electric field. The invention further encompasses protonic transistors comprising a cephalopod proton-conducting protein channel. The transistors and related devices of the invention are amenable to use in biological systems for the sensing or manipulation of protonic flows within the biological system. |
| FILED | Tuesday, October 03, 2017 |
| APPL NO | 15/724253 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4167 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0093 (20130101) H01L 51/0558 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557859 | Wanner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Ina-Beate Wanner (Topanga, California); Joseph A. Loo (Encino, California) |
| ABSTRACT | A method for detection or monitoring status of traumatic brain injury (TBI) or spinal cord injury (SCI) in a subject is provided. In one embodiment, the method comprises contacting a specimen of bodily fluid obtained from the subject with reagents for assaying for a marker of TBI selected from aldolase C (ALDOC) and brain lipid binding protein (BLBP), or a trauma-specific break down product (BDP) of ALDOC or BLBP. The method further comprises measuring the amount of marker present in the specimen as compared to a control sample, and determining the presence of TBI or SCI when an elevated amount of marker is present in the specimen compared to the control sample. The method can comprises measuring the amount of glutamine synthetase (GS), astrocytic phosphoprotein PEA-15 (PEA15), αB-crystallin (CRYAB/HSP27), a cleavage product of ALDOC, GS, PEA15, or CRYAB, or a combination of two or more thereof. |
| FILED | Thursday, May 05, 2016 |
| APPL NO | 15/570982 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Enzymes C12Y 201/01259 (20150701) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/577 (20130101) G01N 33/6848 (20130101) G01N 33/6896 (20130101) Original (OR) Class G01N 2800/40 (20130101) G01N 2800/52 (20130101) G01N 2800/2871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557923 | Watnik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Abbie T. Watnik (Washington, District of Columbia); Paul S. Lebow (Annapolis, Maryland) |
| ABSTRACT | An apparatus for illuminating or masking an object and a method of using same. The apparatus includes a spatial light modulator transmitting, a structured pulsed laser beam from a pupil plane to at least one image plane in a field of view. The apparatus further includes a lidar detector receiving reflected laser beam reflected from the at least one image plane. For example, the lidar detector detects range, position, and/or time data for at least one object of interest or at least one object of disinterest. Using the detected data, the spatial light modulator illuminates object of interest or masks an object of disinterest, depending on a user's application. |
| FILED | Monday, February 22, 2016 |
| APPL NO | 15/049401 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) G01S 7/4815 (20130101) Original (OR) Class G01S 17/89 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557977 | Tabirian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Beam Engineering for Advanced Measurements Co. (Orlando, Florida); U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | Beam Engineering for Advanced Measurements Co. (Orlando, Florida); U.S. Government as represented by the Secretary of the Army (Natick, Massachusetts) |
| INVENTOR(S) | Nelson V. Tabirian (Winter Park, Florida); Svetlana Serak (Oviedo, Florida); Olena Uskova (Winter Park, Florida); David E. Roberts (Apopka, Florida); Anna Tabirian (Winter Park, Florida); Diane Steeves (Franklin, Massachusetts); Brian Kimball (Shrewsbury, Massachusetts) |
| ABSTRACT | Methods, systems and devices for diffractive waveplate lens and mirror systems allowing electronically focusing light at different focal planes. The system can be incorporated into a variety of optical schemes for providing electrical control of transmission. In another embodiment, the system comprises diffractive waveplates of different functionality to provide a system for controlling not only focusing but other propagation properties of light including direction, phase profile, and intensity distribution. |
| FILED | Friday, December 14, 2018 |
| APPL NO | 16/220995 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/1618 (20130101) A61F 2/1654 (20130101) Optical Elements, Systems, or Apparatus G02B 3/10 (20130101) G02B 3/0081 (20130101) G02B 5/001 (20130101) G02B 5/1828 (20130101) G02B 5/1833 (20130101) Original (OR) Class G02B 5/3083 (20130101) G02B 6/024 (20130101) G02B 6/3534 (20130101) G02B 6/3592 (20130101) G02B 27/4205 (20130101) G02B 27/4211 (20130101) G02B 27/4216 (20130101) G02B 27/4261 (20130101) Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 7/10 (20130101) G02C 7/12 (20130101) G02C 7/022 (20130101) G02C 7/061 (20130101) G02C 7/086 (20130101) G02C 2202/16 (20130101) G02C 2202/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557980 | Jungwirth |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Matthew Edward Lewis Jungwirth (Golden Valley, Minnesota) |
| ABSTRACT | A method is provided. The method comprises: receiving incident light, from an object surface, on a top surface of a holographic optical field flattener (HOFF); transforming direction of light, with a hologram, if the light is incident on a portion of the HOFF at an angle equal to a non-zero field angle of the portion; and emitting transformed light from a bottom surface of the HOFF. |
| FILED | Thursday, June 22, 2017 |
| APPL NO | 15/630430 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/025 (20130101) G01C 21/165 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/7862 (20130101) Optical Elements, Systems, or Apparatus G02B 5/32 (20130101) Original (OR) Class Holographic Processes or Apparatus G03H 1/30 (20130101) G03H 1/0272 (20130101) G03H 2001/0439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10558204 | Matei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Ion Matei (Sunnyvale, California); Jeng Ping Lu (Fremont, California); Saigopal Nelaturi (Mountain View, California); Julie A. Bert (East Palo Alto, California); Lara S. Crawford (Belmont, California); Armin R. Volkel (Mountain View, California); Eugene M. Chow (Palo Alto, California) |
| ABSTRACT | The system and method described below allow for real-time control over positioning of a micro-object. A movement of at least one micro-object suspended in a medium can be induced by a generation of one or more forces by electrodes proximate to the micro-object. Prior to inducing the movement, a simulation is used to develop a model describing a parameter of an interaction between each of the electrodes and the micro-object. A function describing the forces generated by an electrode and an extent of the movement induced due to the forces is generated using the model. The function is used to design closed loop policy control scheme for moving the micro-object towards a desired position. The position of the micro-object is tracked and taken into account when generating control signals in the scheme. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 15/469433 |
| ART UNIT | 2118 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 17/02 (20130101) G05B 19/41885 (20130101) Original (OR) Class G05B 2219/32359 (20130101) Image Data Processing or Generation, in General G06T 7/74 (20170101) G06T 7/155 (20170101) G06T 7/194 (20170101) G06T 2207/20021 (20130101) G06T 2207/30164 (20130101) Pictorial Communication, e.g Television H04N 7/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10558249 | Bose et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Pradip Bose (Yorktown Heights, New York); Alper Buyuktosunoglu (White Plains, New York); Timothy Joseph Chainer (Putnam Valley, New York); Pritish Ranjan Parida (Fishkill, New York); Augusto Javier Vega (Astoria, New York) |
| ABSTRACT | Techniques for inducing non-uniform cooling are described. According to an embodiment, a system is provided. The system can comprise at least one processor device that executes components stored in a memory, wherein the components comprise: a flow control device that distributes coolant to a location of the at least one processor device; and a sensor controller component that detects a location of a thermal anomaly of the at least one processor device. The components can also comprise a cooling controller component that adjusts the flow control device to direct the coolant to the location of the thermal anomaly. |
| FILED | Tuesday, September 27, 2016 |
| APPL NO | 15/277725 |
| ART UNIT | 2118 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/50324 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 23/1932 (20130101) Electric Digital Data Processing G06F 1/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10558518 | Nair et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Prashant Jayaprakash Nair (Elmsford, New York); Alper Buyuktosunoglu (White Plains, New York); Pradip Bose (Yorktown Heights, New York) |
| ABSTRACT | A computer monitors a memory system during operation. The computer detects a first number of errors in the memory system. The computer determines that the first number of errors is below an error level threshold. The computer lowers a first group of one or more memory parameters of the memory system by a first amount. After the lowering of one or more memory parameters by the first amount, the computer detects a second number of errors in the memory system. The computer determines that the second number of errors is above the error level threshold. The computer raises a second group of one or more memory parameters of the memory system by a second amount. |
| FILED | Monday, November 13, 2017 |
| APPL NO | 15/810336 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/324 (20130101) G06F 1/3296 (20130101) G06F 3/0604 (20130101) G06F 3/0634 (20130101) G06F 3/0673 (20130101) G06F 11/073 (20130101) G06F 11/076 (20130101) G06F 11/0793 (20130101) Original (OR) Class G06F 11/1008 (20130101) G06F 11/1048 (20130101) Static Stores G11C 16/349 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10558575 | Fleming, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kermin E. Fleming, Jr. (Hudson, Massachusetts); Kent D. Glossop (Merrimack, New Hampshire); Simon C. Steely, Jr. (Hudson, New Hampshire); Jinjie Tang (Acton, Massachusetts); Alan G. Gara (Palo Alto, California) |
| ABSTRACT | Systems, methods, and apparatuses relating to a configurable spatial accelerator are described. In one embodiment, a processor includes a core with a decoder to decode an instruction into a decoded instruction and an execution unit to execute the decoded instruction to perform a first operation; a plurality of processing elements; and an interconnect network between the plurality of processing elements to receive an input of a dataflow graph comprising a plurality of nodes, wherein the dataflow graph is to be overlaid into the interconnect network and the plurality of processing elements with each node represented as a dataflow operator in the plurality of processing elements, and the plurality of processing elements is to perform a second operation when an incoming operand set arrives at the plurality of processing elements. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/396402 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3005 (20130101) G06F 9/3016 (20130101) G06F 9/3802 (20130101) G06F 9/3861 (20130101) G06F 12/0842 (20130101) G06F 12/0862 (20130101) Original (OR) Class G06F 12/0875 (20130101) G06F 2212/62 (20130101) G06F 2212/452 (20130101) G06F 2212/602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10558809 | Joyce et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Robert A. Joyce (Ithaca, New York); Matthew P. Donovan (Trumansburg, New York) |
| ABSTRACT | An example method includes monitoring execution of one or more applications on a runtime computing system that includes a plurality of processing units, receiving, from the runtime computing system during execution of the applications, monitoring information that includes at least one of function call data or application programming interface call data associated with operations performed by the plurality of processing units during execution of the applications, importing the monitoring information into a risk model, analyzing the monitoring information within the risk model to determine one or more potential vulnerabilities and one or more impacts of the one or more vulnerabilities in the runtime computing system, and outputting, for display in a graphical user interface, a graphical representation of the one or more potential vulnerabilities and the one or more impacts within the risk model. |
| FILED | Wednesday, April 12, 2017 |
| APPL NO | 15/485784 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/52 (20130101) G06F 21/577 (20130101) Original (OR) Class G06F 2221/033 (20130101) G06F 2221/034 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 11/60 (20130101) G06T 11/206 (20130101) G06T 2200/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10558892 | Andreopoulos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alexander Andreopoulos (San Jose, California); Rathinakumar Appuswamy (San Jose, California); Pallab Datta (San Jose, California); Steven K. Esser (San Jose, California); Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | Embodiments of the invention provide a method for scene understanding based on a sequence of image frames. The method comprises converting each pixel of each image frame to neural spikes, and extracting features from the sequence of image frames by processing neural spikes corresponding to pixels of the sequence of image frames. The method further comprises encoding the extracted features as neural spikes, and classifying the extracted features. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/147106 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/46 (20130101) G06K 9/52 (20130101) G06K 9/66 (20130101) G06K 9/00718 (20130101) G06K 9/00986 (20130101) G06K 9/4623 (20130101) G06K 9/4652 (20130101) G06K 9/4661 (20130101) G06K 9/4671 (20130101) G06K 9/4676 (20130101) G06K 9/6256 (20130101) Original (OR) Class G06K 9/6267 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0635 (20130101) Image Data Processing or Generation, in General G06T 7/246 (20170101) G06T 2207/10016 (20130101) G06T 2207/20081 (20130101) Pictorial Communication, e.g Television H04N 9/67 (20130101) H04N 19/136 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559058 | Riabov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Anton V. Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (Port Chester, New York); Octavian Udrea (Ossining, New York) |
| ABSTRACT | Techniques for translating graphical representations of domain knowledge are provided. In one example, a computer-implemented method comprises receiving, by a device operatively coupled to a processor, a graphical representation of domain knowledge. The graphical representation comprises information indicative of a central concept and at least one chain of events associated with the central concept. The computer-implemented method further comprises translating, by the device, the graphical representation into an artificial intelligence planning problem. The artificial intelligence planning problem is expressed in an artificial intelligence description language. The translating comprises parsing the graphical representation into groupings of terms. A first grouping of terms of the grouping of terms comprises an event from the at least one chain of events and a second grouping of terms of the grouping of terms comprises the information indicative of the central concept. The computer-implemented method also comprises validating, by the device, the artificial intelligence planning problem. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/296364 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 5/022 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 1/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559392 | Saffman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Mark Saffman (Madison, Wisconsin) |
| ABSTRACT | A system and method for controlling particles using projected light are provided. In some aspects, the method includes generating a beam of light using an optical source, and directing the beam of light to a beam filter comprising a first mask, a first lens, a second mask, and a second lens. The method also includes forming an optical pattern using the beam filter, and projecting the optical pattern on a plurality of particles to control their locations in space. |
| FILED | Friday, January 04, 2019 |
| APPL NO | 16/239997 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559518 | Chainer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Timothy J. Chainer (Putnam Valley, New York); Pritish R. Parida (Stamford, Connecticut); Fanghao Yang (Somerset, New Jersey) |
| ABSTRACT | A method of forming metallic pillars between a fluid inlet and outlet for two-phase fluid cooling. The method may include; forming an arrangement of metallic pillars between two structures, the metallic pillars are electrically connected to metallic connecting lines that run through each of the two structures, the arrangement of metallic pillars located between a fluid inlet and a fluid channel, the fluid channel having channel walls running between arrangements of the metallic pillars and a fluid outlet, whereby a fluid passes through the arrangement of metallic pillars to flow into the fluid channel. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/030909 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4882 (20130101) H01L 23/02 (20130101) H01L 23/427 (20130101) H01L 23/473 (20130101) Original (OR) Class H01L 23/3675 (20130101) H01L 25/0657 (20130101) H01L 2225/06513 (20130101) H01L 2225/06589 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559704 | Meyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jerry R. Meyer (Catonsville, Maryland); Igor Vurgaftman (Severna Park, Maryland); Chadwick Lawrence Canedy (Washington, District of Columbia); William W. Bewley (Falls Church, Virginia); Chul Soo Kim (Springfield, Virginia); Charles D. Merritt (Fairfax, Virginia); Michael V. Warren (Arlington, Virginia); Mijin Kim (Springfield, Virginia) |
| ABSTRACT | Resonant-cavity infrared photodetector (RCID) devices that include a thin absorber layer contained entirely within the resonant cavity. In some embodiments, the absorber is a single type-II InAs—GaSb interface situated between an AlSb/InAs superlattice n-type region and a p-type AlSb/GaSb region. In other embodiments, the absorber region comprises quantum wells formed on an upper surface of the n-type region. In other embodiments, the absorber region comprises a “W”-structured quantum well situated between two barrier layers, the “W”-structured quantum well comprising a hole quantum well sandwiched between two electron quantum wells. In other embodiments, the RCID includes a thin absorber region and an nBn or pBp active core within a resonant cavity. In some embodiments, the RCID is configured to absorb incident light propagating in the direction of the epitaxial growth of the RCID structure, while in other embodiments, it absorbs light propagating in the epitaxial plane of the structure. |
| FILED | Tuesday, October 23, 2018 |
| APPL NO | 16/167729 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) G01N 21/552 (20130101) G01N 21/3504 (20130101) G01N 21/7746 (20130101) Optical Elements, Systems, or Apparatus G02B 6/124 (20130101) G02B 6/12004 (20130101) G02B 2006/12061 (20130101) G02B 2006/12078 (20130101) G02B 2006/12123 (20130101) G02B 2006/12138 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/105 (20130101) H01L 31/109 (20130101) H01L 31/02325 (20130101) H01L 31/02327 (20130101) Original (OR) Class H01L 31/03046 (20130101) H01L 31/035209 (20130101) H01L 31/035236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559747 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Yufan Li (Baltimore, Maryland); Qinli Ma (Baltimore, Maryland); Chia-ling Chien (Cockeysville, Maryland) |
| ABSTRACT | A magneto-electronic device may include: a spin-orbit torque (SOT) generator layer; a magnetic memory layer; and/or sensing electrodes configured to measure a Hall effect of the magnetic memory layer. The SOT generator layer may include topological insulator material, and the magnetic memory layer may include ferromagnetic material with perpendicular magnetic anisotropy. A magneto-electronic device may include: a spin-orbit torque (SOT) generator layer; a first magnetic memory layer on the SOT generator layer; an insulating layer on the first magnetic memory layer; and/or a second magnetic memory layer on the insulating layer. The SOT generator layer may include topological insulator material. The first magnetic memory layer and the second magnetic memory layer may include ferromagnetic material with either perpendicular magnetic anisotropy or in-plane magnetic anisotropy. |
| FILED | Wednesday, April 26, 2017 |
| APPL NO | 15/497591 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/18 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/04 (20130101) H01L 43/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10560192 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jerry T. Kim (Washington, District of Columbia); Margaret Cheney (Fort Collins, Colorado) |
| ABSTRACT | In certain embodiments, a system for transmitting (electromagnetic or acoustic) wave-based signals towards a target includes a plurality of transceivers and a controller. Each transceiver transmits a probe signal towards the target and receives an associated backscatter signal corresponding to reflection of the probe signals from the target. The controller determines, for each transceiver, a Doppler frequency shift and a time delay, modifies each associated backscatter signal based on the corresponding Doppler frequency shift and time delay to generate an associated motion-compensated backscatter signal, and applies time reversal (TR) processing to each motion-compensated backscatter signal to generate an associated motion-compensated TR signal. Each transceiver transmits towards the target a transmission signal based the associated motion-compensated TR signal. In communications systems, the transmission signals are data-modulated versions of the motion-compensated TR signals. In radar and sonar systems, the transmission signals are the motion-compensated TR signals. |
| FILED | Monday, March 05, 2018 |
| APPL NO | 15/911764 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Transmission H04B 1/74 (20130101) H04B 1/0475 (20130101) H04B 10/40 (20130101) H04B 10/548 (20130101) Original (OR) Class H04B 10/2575 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D874835 | Stier |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SWISS CONFEDERATION REPRESENTED BY ARMASUISSE THE FEDERAL DEPARTMENT OF DEFENSE CIVIL PROTECTION AND SPORTS (Bern, Switzerland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andreas Stier (Bern, Switzerland) |
| ABSTRACT | |
| FILED | Wednesday, May 30, 2018 |
| APPL NO | 35/505749 |
| ART UNIT | 2918 — Design |
| CURRENT CPC | Textile or paper yard goods; sheet material D5/63 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10555689 | Marquez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Juan Sebastian Marquez (Miami, Florida); Ou Bai (Sunrise, Florida); Roozbeh Atri (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Juan Sebastian Marquez (Miami, Florida); Ou Bai (Sunrise, Florida); Roozbeh Atri (Miami, Florida) |
| ABSTRACT | A cyber-physical system (CPS) pressure based sensing system and methods for assessing stance or mobility of a test subject standing or moving are provided. The CPS pressure based sensing system can include at least one piezoresistive transducer configured to obtain a plurality of measurements with respect to the stance or movements of the test subject, and a data analyzer configured to determine patterns of the stance or movement by performing machine learning classification on the plurality of measurements obtained by the at least one piezoresistive transducer. |
| FILED | Friday, February 08, 2019 |
| APPL NO | 16/270909 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/112 (20130101) A61B 5/1038 (20130101) Original (OR) Class A61B 2562/0247 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555694 | Cooks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Zheng Ouyang (West Lafayette, Indiana); Chien-hsun Chen (West Lafayette, Indiana); Ziqing Lin (West Lafayette, Indiana); Livia Schiavinato Eberlin (Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member. |
| FILED | Tuesday, August 13, 2019 |
| APPL NO | 16/539562 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/145 (20130101) A61B 5/157 (20130101) A61B 5/1405 (20130101) A61B 5/1477 (20130101) Original (OR) Class A61B 5/150015 (20130101) A61B 5/150992 (20130101) A61B 10/0045 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/00 (20130101) A61M 25/00 (20130101) A61M 2202/0468 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) G01N 2001/028 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0022 (20130101) H01J 49/34 (20130101) H01J 49/167 (20130101) H01J 49/0404 (20130101) H01J 49/0445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555865 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Juanjuan Zhang (Pittsburgh, Pennsylvania); Steven H. Collins (Pittsburgh, Pennsylvania) |
| ABSTRACT | This document describes systems and methods for controlling an exoskeleton. The system receives a measurement of a first torque applied to a rotational joint coupling a first component to a second component, the first torque being applied by a motor via a cable. The system determines, based on the measurement of the first torque, a first portion of a second torque to apply to the rotational joint. The system determines, based on the measurement of the first torque, a second portion of the second torque to apply to the rotational joint. The system determines a value of the second torque to apply to the rotational joint based on the first portion and the second portion. The system controls the motor for applying the second torque to the rotational joint via the cable. |
| FILED | Thursday, May 25, 2017 |
| APPL NO | 15/605520 |
| ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) Original (OR) Class A61H 2003/007 (20130101) A61H 2201/1223 (20130101) A61H 2201/5007 (20130101) A61H 2201/5061 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 1/12 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 6/02 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 17/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556222 | Grubbs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Albany, New York) |
| INVENTOR(S) | Robert B. Grubbs (Miller Place, New York); Benjamin S. Hsiao (Setauket, New York); Benjamin Chu (Setauket, New York); Rui Yang (Fair Lawn, New Jersey) |
| ABSTRACT | Water filtration membranes are provided. Such membranes include polysaccharide fibers that have been modified to possess thiol groups thereon, resulting in materials that effectively bind heavy metal ions. The resulting fibers may be used by themselves or applied to a scaffold to form a membrane suitable for removing heavy metals from water, including groundwater. |
| FILED | Thursday, March 10, 2016 |
| APPL NO | 15/065972 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 67/002 (20130101) B01D 67/0093 (20130101) B01D 71/08 (20130101) B01D 71/10 (20130101) B01D 2323/36 (20130101) B01D 2323/39 (20130101) B01D 2325/12 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/265 (20130101) Original (OR) Class B01J 20/3085 (20130101) B01J 20/28038 (20130101) B01J 20/28083 (20130101) B01J 20/28085 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/444 (20130101) C02F 2101/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556803 | Wilcox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado School of Mines (Golden, Colorado) |
| ASSIGNEE(S) | Colorado School of Mines (Golden, Colorado) |
| INVENTOR(S) | Jennifer Wilcox (Golden, Colorado); Simona Liguori (Lakewood, Colorado) |
| ABSTRACT | The invention relates to a metallic membrane for nitrogen separation, the method of making the membrane and methods of using the membrane. The invention also relates to a metallic membrane for disassociation of nitrogen and subsequent reaction with hydrogen to produce ammonia at moderate conditions compared to a conventional Haber-Bosch process. |
| FILED | Monday, September 18, 2017 |
| APPL NO | 15/707007 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 69/02 (20130101) B01D 71/022 (20130101) B01D 2311/2696 (20130101) B01D 2325/10 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/2475 (20130101) B01J 35/065 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/0411 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556839 | Temme et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pivot Bio, Inc. (Berkeley, California) |
| ASSIGNEE(S) | Pivot Bio, Inc. (Berkeley, California) |
| INVENTOR(S) | Karsten Temme (Oakland, California); Alvin Tamsir (San Francisco, California); Sarah Bloch (Oakland, California); Rosemary Clark (Emeryville, California); Emily Tung (Millbrae, California) |
| ABSTRACT | Disclosed herein are methods of increasing nitrogen fixation in a non-leguminous plant. The methods can comprise exposing the plant to a plurality of bacteria. Each member of the plurality comprises one or more genetic variations introduced into one or more genes or non-coding polynucleotides of the bacteria's nitrogen fixation or assimilation genetic regulatory network, such that the bacteria are capable of fixing atmospheric nitrogen in the presence of exogenous nitrogen. The bacteria are not intergeneric microorganisms. Additionally, the bacteria, in planta, produce 1% or more of the fixed nitrogen in the plant. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/954557 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Nitrogenous Fertilisers C05C 1/00 (20130101) C05C 1/00 (20130101) C05C 3/005 (20130101) C05C 3/005 (20130101) C05C 5/005 (20130101) C05C 5/005 (20130101) C05C 11/00 (20130101) C05C 11/00 (20130101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class C05F 11/08 (20130101) C05F 11/08 (20130101) C05F 11/08 (20130101) C05F 11/08 (20130101) Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/80 (20130101) C12N 9/93 (20130101) C12N 9/0095 (20130101) Enzymes C12Y 118/06001 (20130101) C12Y 305/01002 (20130101) C12Y 603/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556852 | Bond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jesse Quentin Bond (Syracuse, New York); Anargyros Chatzidimitriou (Syracuse, New York) |
| ASSIGNEE(S) | SYRACUSE UNIVERSITY (Syracuse, New York) |
| INVENTOR(S) | Jesse Quentin Bond (Syracuse, New York); Anargyros Chatzidimitriou (Syracuse, New York) |
| ABSTRACT | A system and method for the conversion of a levulinate ester to maleic anhydride using a reducible oxide catalyst. Levulinic acid oxidation delivers maleic anhydride in good yields without viscosity and stability issues that make continuous production problematic. Due to the fact that levulinate esters are more amenable to processing, the conversion of levulinate esters to maleic anhydride represents an appropriate for the commercial production of maleic anhydride from renewable resources. |
| FILED | Friday, June 08, 2018 |
| APPL NO | 16/003330 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 23/22 (20130101) B01J 37/14 (20130101) B01J 37/0036 (20130101) B01J 37/0201 (20130101) Acyclic or Carbocyclic Compounds C07C 51/313 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556921 | Williams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Travis J. Williams (Los Angeles, California); Jeff Joseph A. Celaje (Arcadia, California); Zhiyao Lu (Duarte, California) |
| ABSTRACT | A formic acid decomposition catalyst system includes organometallic complexes having formula 1: wherein: M is a transition metal; E is P, N, or C (as in imidazolium carbene); R1, R2 are independently C1-6 alkyl groups; o is 1, 2, 3, or 4; R3 are independently hydrogen, C1-6 alkyl groups, OR14, NO2, halogen; R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R15, R16 are independently hydrogen or C1-6 alkyl groups; R14 is a C1-6 alkyl group; and X− is a negatively charge counter ion. |
| FILED | Monday, January 14, 2019 |
| APPL NO | 16/246872 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/181 (20130101) B01J 31/189 (20130101) B01J 31/2239 (20130101) B01J 31/2295 (20130101) B01J 2231/763 (20130101) B01J 2531/827 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/22 (20130101) C01B 2203/0277 (20130101) C01B 2203/1064 (20130101) C01B 2203/1211 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/004 (20130101) Original (OR) Class C07F 15/0033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557042 | Lynn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David M. Lynn (Middleton, Wisconsin); Uttam Manna (Guwahati, India) |
| ABSTRACT | The present invention provides polymer-based slippery liquid-infused porous surfaces (SLIPS) that can prevent adhesion and colonization by fungal and bacterial pathogens and also kill and/or attenuate the colonization and virulence of non-adherent pathogens in surrounding media. The present approach exploits the polymer and liquid oil phases in these slippery materials to sustain the release of small molecules such as a broad-spectrum antimicrobial agent, an antifungal agent, an antibacterial agent, an agent that modulates bacterial or fungal quorum sensing, an agent that attenuates virulence, or a combination thereof. This controlled release approach improves the inherent anti-fouling properties of SLIPS, has the potential to be general in scope, and expands the potential utility of slippery, non-fouling surfaces in both fundamental and applied contexts. |
| FILED | Tuesday, March 28, 2017 |
| APPL NO | 15/471628 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/73 (20130101) Heterocyclic Compounds C07D 235/28 (20130101) C07D 235/30 (20130101) C07D 307/12 (20130101) C07D 307/14 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) Original (OR) Class C09D 5/1625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557044 | Lynn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David Lynn (Middleton, Wisconsin); Uttam Manna (Madison, Wisconsin); Matthew Carter (Madison, Wisconsin) |
| ABSTRACT | This invention provides slippery liquid-infused porous surfaces (SLIPS) using nanoporous or microporous and chemically reactive polymer multilayers. This approach permits fabrication of slippery anti-fouling coatings on complex surfaces and provides new means to manipulate the mobilities of contacting aqueous fluids. The results expand the range of tools that can be used to manipulate the behaviors of SLIPS and open the door to new applications of this emerging class of soft materials. |
| FILED | Friday, June 24, 2016 |
| APPL NO | 15/192425 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1625 (20130101) Original (OR) Class C09D 5/1668 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557054 | Gopalan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Padma Gopalan (Madison, Wisconsin); William L. Murphy (Waunakee, Wisconsin); Samantha Kelly Schmitt (Madison, Wisconsin) |
| ABSTRACT | Random copolymers, crosslinked thin films of the random copolymers and cell culture substrates comprising the crosslinked thin films are provided. Also provided are methods of making and using the copolymers, thin films and substrates. The copolymers are polymerized from glycidyl methacrylate monomers and vinyl azlactone monomers. The crosslinked thin films are substrate independent, in that they need not be covalently bound to a substrate to form a stable film on the substrate surface. |
| FILED | Tuesday, August 01, 2017 |
| APPL NO | 15/665831 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/28 (20130101) C08F 226/06 (20130101) C08F 2220/286 (20130101) C08F 2220/325 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 133/14 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 2533/40 (20130101) C12N 2537/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557145 | Martin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH (Ithaca, New York) |
| ASSIGNEE(S) | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (Ithaca, New York) |
| INVENTOR(S) | Gregory B. Martin (Ithaca, New York); Sarah R. Hind (Ithaca, New York); Susan R. Strickler (Ithaca, New York) |
| ABSTRACT | One aspect of the present invention relates to a nucleic acid construct that includes a nucleic acid molecule that encodes FLAGELLIN-SENSING 3 (“FLS3”) protein; a 5′ heterologous DNA promoter sequence; and a 3′ terminator sequence, where the nucleic acid molecule, the DNA promoter sequence, and the terminator sequence are operatively coupled to permit transcription of the nucleic acid molecule. The present invention also relates to a method of imparting disease resistance to a plant. This method involves transforming a plant or a plant seed with a nucleic acid molecule that increases expression of an FLS3 protein, where said transforming is effective in imparting disease resistance to the transformed plant or to a transgenic plant produced from the transformed plant seed. The present invention also relates to methods of expressing a nucleic acid molecule in a plant, identifying a candidate plant suitable for breeding that displays enhanced disease resistance, and enhancing efficiency of transformation of a plant by Agrobacterium. |
| FILED | Wednesday, July 08, 2015 |
| APPL NO | 15/324389 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) C12N 15/8279 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) C12Q 2600/13 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557160 | Ellington et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Andrew D. Ellington (Austin, Texas); Ross Thyer (Austin, Texas) |
| ABSTRACT | Recombinant bacterial cells are provided that comprise a stable non-canonical amino acid translation pathway. In some aspects, the bacteria comprise nucleic acids encoding a non-canonical amino acid translation pathway (e.g., a tRNA for incorporation of a non-canonical amino acid, such selenocysteine); a marker polypeptide that includes the non-canonical amino acid. Recombinant tRNA and selection marker coding sequences are likewise provided. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 15/380560 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/86 (20130101) C12N 9/93 (20130101) C12N 15/11 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class Enzymes C12Y 305/02006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557182 | Monroe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James A. Monroe (College Station, Texas); Ibrahim Karaman (College Station, Texas); Raymundo Arroyave (College Station, Texas) |
| ABSTRACT | Systems and methods disclosed herein relate to the manufacture of metallic material with a thermal expansion coefficient in a predetermined range, comprising: deforming, a metallic material comprising a first phase and a first thermal expansion coefficient. In response to the deformation, at least some of the first phase is transformed into a second phase, wherein the second phase comprises martensite, and orienting the metallic material in at least one predetermined orientation, wherein the metallic material, subsequent to deformation, comprises a second thermal expansion coefficient, wherein the second thermal expansion coefficient is within a predetermined range, and wherein the thermal expansion is in at least one predetermined direction. In some embodiments, the metallic material comprises the second phase and is thermo-mechanically deformed to orient the grains in at least one direction. |
| FILED | Thursday, June 12, 2014 |
| APPL NO | 14/897904 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 8/065 (20130101) C21D 8/0205 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/08 (20130101) C22F 1/10 (20130101) C22F 1/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557763 | Khizroev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sakhrat Khizroev (Miami, Florida); Rakesh Guduru (Miami, Florida); Dwayne McDaniel (Miramar, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Sakhrat Khizroev (Miami, Florida); Rakesh Guduru (Miami, Florida); Dwayne McDaniel (Miramar, Florida) |
| ABSTRACT | Systems for screening and health monitoring of materials are provided. The system can include a material embedded with magneto-electric nanoparticles (MENs), a laser configured to direct incident laser light waves at a target area of the material, an optical filter disposed between the laser and the material, and an analyzer configured to detect the laser light reflected from the material. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/235881 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/12 (20130101) G01L 1/247 (20130101) Original (OR) Class Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 5/0091 (20130101) G01M 11/005 (20130101) Optical Elements, Systems, or Apparatus G02B 27/288 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0045 (20130101) H01F 1/0054 (20130101) H01F 1/344 (20130101) H01F 27/255 (20130101) H01F 27/2804 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/1132 (20130101) H01L 41/1871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557789 | Prater et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bruker Nano, Inc. (Santa Barbara, California) |
| ASSIGNEE(S) | Bruker Nano, Inc. (Santa Barbara, California) |
| INVENTOR(S) | Craig Prater (Santa Barbara, California); Kevin Kjoller (Santa Barbara, California); Doug Gotthard (Santa Barbara, California); Qichi Hu (Camarillo, California) |
| ABSTRACT | Described are techniques for obtaining spectroscopic information from sub-micron regions of a sample using a probe microscope. The current invention uses the response of an AFM cantilever at a plurality of frequencies to substantially reduce the impact of background absorption away from the sub-micron region of interest. This innovation substantially improves the quality of spectra for top down illumination of samples that are not suitable for bottoms up illumination of the prior art. |
| FILED | Wednesday, July 31, 2013 |
| APPL NO | 13/956156 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/35 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557807 | Ros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Alexandra Ros (Phoenix, Arizona); Gerrit Brehm (Göttingen, Germany); Garrett Nelson (Mesa, Arizona); John Spence (Tempe, Arizona); Uwe Weierstall (Phoenix, Arizona); Austin Echelmeier (Tempe, Arizona) |
| ABSTRACT | A 3D printed hybrid nozzle device combining a microfluidic mixer with a liquid jet injector that addresses the bottleneck of investigating substrate-initiated biological reaction paths employing serial crystallography with XFELs. The hybrid nozzle provides for injecting aqueous protein crystal jets after fast mixing (<5 ms), reaching reaction time points (e.g., about 10 ms to about 150 ms) suitable to resolve enzyme kinetics. |
| FILED | Tuesday, May 22, 2018 |
| APPL NO | 16/328262 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/0062 (20130101) B01F 2215/0037 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2300/0867 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/2005 (20130101) Original (OR) Class G01N 23/20025 (20130101) G01N 2223/602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557810 | Stokes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Malcolm Stokes (La Jolla, California); Charlotte M. Beall (La Jolla, California) |
| ABSTRACT | Methods, systems, and devices are disclosed for implementing an exemplary immersion mode ice spectrometer. In order to increase sample throughput and improve accuracy of Ice Nucleating Particle (INP) freezing temperature measurement, the exemplary immersion mode ice spectrometer both increases sample cooling rates and monitors changes in optical properties of water droplets during freezing. |
| FILED | Tuesday, October 03, 2017 |
| APPL NO | 15/724079 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 9/006 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/2823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/06 (20130101) Original (OR) Class Meteorology G01W 1/00 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 19/02 (20130101) G08B 21/187 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557820 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (Notre Dame, Indiana) |
| ASSIGNEE(S) | UNIVERSITY OF NOTRE DAME DU LAC (Notre Dame, Indiana) |
| INVENTOR(S) | Hsueh-Chia Chang (Granger, Indiana); Zdenek Slouka (South Bend, Indiana); Satyajyoti Senapati (Mishawaka, Indiana); Li-Jing Cheng (Granger, Indiana) |
| ABSTRACT | A DNA/RNA detection technology is provided. The open flow detection technique includes a substrate defining a pair of opposing microchannels, a pair of opposing electrodes in the opposing microchannels, and at least one ion exchanging nanomembrane coupled between the opposing microchannels such that the opposing microchannels are connected to each other only through the nanomembrane, wherein the nanomembrane is functionalized with a probe complementary to the macromolecule. A voltammeter is provided to measure the electrical current or potential across the nanomembrane, and detect a change in the measured electrical current or potential to quantify the presence of the macromolecule. |
| FILED | Friday, February 12, 2016 |
| APPL NO | 15/043401 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4146 (20130101) G01N 27/44704 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557855 | Korgel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); Alma Mater Studiorum Università di Bologna (Bologna, Italy) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas); Alma Mater Studiorum Universita di Bologna (Bologna, Italy) |
| INVENTOR(S) | Brian A. Korgel (Round Rock, Texas); Yixuan Yu (Austin, Texas); Paola Ceroni (Bagnara di Romagna, Italy); Giacomo Bergamini (Bologna, Italy); Mirko Locritani (Taranto, Italy) |
| ABSTRACT | Systems comprising a nanocrystal and a luminescent chromophore are disclosed herein. The luminescent chromophore can emit energy having a first wavelength. The luminescent chromophore is configured to transfer the emitted energy having a first wavelength to the nanocrystal. The luminescent chromophore can be linked to the nanocrystal via a covalent bond. Absorption of the energy having first wavelength by the nanocrystal can activate the nanocrystal and result in an increase in quantum yield. In some embodiments, the nanocrystal can include silicon, germanium, carbon, or combinations thereof. In some examples, the luminescent chromophore can be pyrene. The luminescent chromophore and the silicon containing nanocrystal can be in a ratio of about 1:1 to 100:1 in the nanocrystal system. Methods of making and using the system are also disclosed. |
| FILED | Wednesday, August 19, 2015 |
| APPL NO | 15/504909 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1011 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/588 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/92 (20130101) Y10S 977/774 (20130101) Y10S 977/896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10558583 | Narasimhan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Giri Narasimhan (Miami Beach, Florida); Giuseppe Vietri (Miami, Florida); Wendy A. Martinez (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Giri Narasimhan (Miami Beach, Florida); Giuseppe Vietri (Miami, Florida); Wendy A. Martinez (Miami, Florida) |
| ABSTRACT | Systems and methods for management of a computer-based cache are provided. A system can include a processor, a cache, a memory device, and a storage device. The processor can be configured to evict a page from the cache to a history index based upon a greater weight respectively assigned to a least frequently used (LFU) and least recently used policy (LRU) policy, detect a requested page that was evicted to the history index, and adjust the respective weights assigned to the policies based upon the requested page being in the history index. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/263690 |
| ART UNIT | 2132 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 5/06 (20130101) G06F 12/123 (20130101) Original (OR) Class G06F 12/0891 (20130101) G06F 17/18 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559392 | Saffman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Mark Saffman (Madison, Wisconsin) |
| ABSTRACT | A system and method for controlling particles using projected light are provided. In some aspects, the method includes generating a beam of light using an optical source, and directing the beam of light to a beam filter comprising a first mask, a first lens, a second mask, and a second lens. The method also includes forming an optical pattern using the beam filter, and projecting the optical pattern on a plurality of particles to control their locations in space. |
| FILED | Friday, January 04, 2019 |
| APPL NO | 16/239997 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559455 | Cooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Depanjan Sarkar (Chennai, India); Thalappil Pradeep (Madras, India); Rahul Narayanan (Chennai, India) |
| ABSTRACT | The invention generally relates to mass spectrometry probes and systems for ionizing a sample. In certain embodiments, the invention provides a mass spectrometry probe including a substrate in which a portion of the substrate is coated with a material, a portion of which protrudes from the substrate. |
| FILED | Friday, July 19, 2019 |
| APPL NO | 16/516823 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/0013 (20130101) H01J 49/16 (20130101) H01J 49/165 (20130101) Original (OR) Class H01J 49/0409 (20130101) H01J 49/0431 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559811 | Zhamu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, Gyeonggi-do, South Korea) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Gyeonggi-Do, South Korea) |
| INVENTOR(S) | Aruna Zhamu (Centerville, Ohio); Jinjun Shi (Hilliard, Ohio); Guorong Chen (Fairborn, Ohio); Qing Fang (Fairborn, Ohio); Bor Z. Jang (Centerville, Ohio) |
| ABSTRACT | A nano graphene-enhanced particulate for use as a lithium-ion battery anode active material, wherein the particulate is formed of a single sheet of graphene or a plurality of graphene sheets and a plurality of fine anode active material particles with a size smaller than 10 μm. The graphene sheets and the particles are mutually bonded or agglomerated into the particulate with at least a graphene sheet embracing the anode active material particles. The amount of graphene is at least 0.01% by weight and the amount of the anode active material is at least 0.1% by weight, all based on the total weight of the particulate. A lithium-ion battery having an anode containing these graphene-enhanced particulates exhibits a stable charge and discharge cycling response, a high specific capacity per unit mass, a high first-cycle efficiency, a high capacity per electrode volume, and a long cycle life. |
| FILED | Wednesday, January 11, 2017 |
| APPL NO | 15/403759 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/48 (20130101) H01M 4/131 (20130101) H01M 4/133 (20130101) Original (OR) Class H01M 4/139 (20130101) H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/0471 (20130101) H01M 4/483 (20130101) H01M 4/523 (20130101) H01M 4/587 (20130101) H01M 4/625 (20130101) H01M 4/5825 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559885 | Morgan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Associated Universities, Inc. (Washington, District of Columbia) |
| ASSIGNEE(S) | Associated Universities, Inc. (Washington, District of Columbia) |
| INVENTOR(S) | Matthew Alexander Morgan (Earlysville, Virginia) |
| ABSTRACT | A TEM line to double-ridged waveguide launcher and horn antenna are disclosed. The launcher uses multiple probes or one or more wide-aspect probes across the ridge gap to minimize spreading inductance and a TEM combiner or matching taper to match the impedance of the probes over a broad bandwidth. The horn uses a power-law scaling of gap height relative to the other dimensions of the horn's taper in order to provide a monotonic decrease of cutoff frequencies in all high-order modes. Both of these techniques permit the implementation of ultra-wideband designs at high frequencies where fabrication tolerances are most difficult to meet. |
| FILED | Thursday, January 24, 2019 |
| APPL NO | 16/256673 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/123 (20130101) H01P 5/103 (20130101) Antennas, i.e Radio Aerials H01Q 13/06 (20130101) H01Q 13/0275 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10560257 | Hoffstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Jeffrey Hoffstein (Providence, Rhode Island); Joseph H. Silverman (Needham, Massachusetts) |
| ABSTRACT | Systems, methods, and computer-readable storage devices storing instructions for homomorphic encryption via finite ring isomorphisms are provided. An example method includes selecting a polynomial f(x) of exact degree n with small coefficients in a ring Fq[x] and selecting a polynomial h(y) of exact degree n in a ring Fq[y]. The method includes constructing an isomorphism from the ring Fq[x]/(f(x)) to the ring Fq[y]/(h(y)) and constructing an inverse isomorphism from the ring Fq[y]/(h(y)) to the ring Fq[x]/(f(x)). The method includes encrypting a message using said isomorphism from the ring Fq[x]/(f(x)) to the ring Fq[y]/(h(y)) and transmitting the encrypted message to a remote computer. The method also includes receiving one or more encrypted response messages from the remote computer based at least in part on the transmitted message and decrypting the one or more encrypted response messages. |
| FILED | Friday, July 08, 2016 |
| APPL NO | 15/742837 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) Original (OR) Class H04L 9/0618 (20130101) H04L 2209/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10556206 | Xiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Xin Xiao (Augusta, Georgia); Henry T. Sessions (Aiken, South Carolina); Lucas M. Angelette (Augusta, Georgia); Paul R. Beaumont (Aiken, South Carolina); David W. Babineau (Aiken, South Carolina) |
| ABSTRACT | Methods and systems for the separation of isotopes from an aqueous stream are described as can be utilized in one embodiment to remove and recover tritium from contaminated water. Methods include counter-current flow of an aqueous stream on either side of a separation membrane. The separation membrane includes an isotope selective layer (e.g., graphene) and an ion conductive supporting layer (e.g., Nafion®). An electronic driving force encourages passage of isotopes selectively across the membrane to enrich the flow in the isotopes. |
| FILED | Wednesday, August 31, 2016 |
| APPL NO | 15/252805 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 59/42 (20130101) Original (OR) Class B01D 69/08 (20130101) B01D 71/021 (20130101) B01D 71/022 (20130101) B01D 71/32 (20130101) Non-metallic Elements; Compounds Thereof; C01B 4/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/66 (20130101) C02F 1/469 (20130101) C02F 2101/006 (20130101) C02F 2101/10 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556604 | Plant |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois) |
| INVENTOR(S) | Derek L. Plant (Batavia, Illinois) |
| ABSTRACT | A train safety system comprises a cable connected to at least two conducting contacts, an electrical load between said two conducting magnetic contacts, and a DC track circuit associated with railroad tracks wherein the at least two conducting plates can be connected to each of the railroad rails in order to shunt the DC track circuit and alert oncoming trains of fouling of the tracks or crossing ahead. |
| FILED | Wednesday, April 12, 2017 |
| APPL NO | 15/485411 |
| ART UNIT | 3617 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Guiding Railway Traffic; Ensuring the Safety of Railway Traffic B61L 1/185 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556917 | Dzwiniel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Trevor L. Dzwiniel (Carol Stream, Illinois); Krzysztof Pupek (Plainfield, Illinois) |
| ABSTRACT | Carbonate esters of Formula (I): (R1)(R2)(R3)Si—R4—O—C(═O)—O—R4—Si(R1)(R2)(R3) are prepared by reaction of a silyl-substituted alcohol of Formula (II): (R1)(R2)(R3)Si—R4—OH with an activated carbonyl compound of Formula (III): C(═O)Z2 in the presence of a catalyst (e.g., an bicyclic amidine, a bicyclic guanidine, or a phosphazene) in an aprotic solvent. In Formulas (I) and (II) each of R1 and R2 independently is alkyl; R3 is alkyl or —X1—Si(R5)(R6)(R7); X1 is O or alkylene; R4 is alkylene; and each R5, R6, and R7 independently is alkyl. In Formula (III), Z is 1-N-imidazolyl or 1-N-succinimidyl. In some embodiments, the catalyst used in the methods described herein comprises at least one base selected from the group consisting of a bicyclic amidine and a bicyclic guanidine. The reaction proceeds readily under both bulk and continuous flow reactor conditions. |
| FILED | Thursday, July 11, 2019 |
| APPL NO | 16/508550 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0251 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/00 (20130101) C07F 7/02 (20130101) C07F 7/08 (20130101) C07F 7/083 (20130101) Original (OR) Class C07F 7/0803 (20130101) C07F 7/0825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557152 | D'Espaux et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Leopold D'Espaux (San Francisco, California); Jay D. Keasling (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Leopold D'Espaux (San Francisco, California); Jay D. Keasling (Berkeley, California) |
| ABSTRACT | The present invention provides for a genetically modified yeast cell comprising at least six or more of the following modifications: increased expression of Mus musculus fatty acid reductase, acetyl-CoA carboxylase, fatty acid synthase 1, fatty acid synthase 2, a mutant of the bottleneck enzyme encoded by ACC1 insensitive to post-transcriptional and post-translational repression, and/or a desaturase encoded by OLE1, and reduced expression of DGA1, HFD1, ADH6, and/or GDH1. The present invention provides a method for constructing the genetically modified yeast cell, and a method for producing a fatty alcohol from the genetically modified yeast cell. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/979144 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0008 (20130101) C12N 9/93 (20130101) C12N 9/1029 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) Original (OR) Class Enzymes C12Y 102/01084 (20150701) C12Y 203/01085 (20130101) C12Y 604/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557155 | Wawrousek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Wyoming Research Corporation (Laramie, Wyoming) |
| ASSIGNEE(S) | The University of Wyoming Research Corporation (Laramie, Wyoming) |
| INVENTOR(S) | Karen E. Wawrousek (Laramie, Wyoming); Patrick Richards (Seattle, Washington); Alan E. Bland (Laramie, Wyoming) |
| ABSTRACT | Methods and systems for the biological conversion of pretreated or solubilized coal or waste coal into biofuels. Coal (10) may be pretreated perhaps in a pretreatment reactor (13). Pretreated coal or even solubilized coal may be introduced into a processing reactor such as a bioreactor (16) containing a plurality of microorganisms (9) such as oleaginous microorganisms which can convert at least some of the pretreated or solubilized coal into lipids (19) or biomass (18), which then may be used directly or as a precursor for various products such as biofuels, feedstock, or the like. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/776272 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/026 (20130101) C10L 2200/0476 (20130101) C10L 2270/026 (20130101) C10L 2290/26 (20130101) C10L 2290/44 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/649 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557391 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADVANCED COOLING TECHNOLOGIES, INC. (Lancaster, Pennsylvania) |
| ASSIGNEE(S) | ADVANCED COOLING TECHNOLOGIES, INC. (Lancaster, Pennsylvania) |
| INVENTOR(S) | Chien-Hua Chen (Lititz, Pennsylvania); Bradley Richard (Lititz, Pennsylvania); Howard Pearlman (Haddon Township, New Jersey); Joel Crawmer (Lancaster, Pennsylvania) |
| ABSTRACT | An incineration system includes an inlet channel supplying an inlet stream comprising a waste gas containing at least one volatile organic compound, a waste gas sensor measuring at least one property of the waste gas, an oxidizing gas supply controllably providing oxidizing gas to the inlet channel, an incinerator receiving the inlet stream from the inlet channel, an ignitor initiating combustion of the inlet stream in the reaction zone of the incinerator, and a controller receiving data from the waste gas sensor and controlling flow of oxidizing gas from the oxidizing gas supply into the inlet channel. The spiral heat exchanger defines a reaction zone, an incoming path from the inlet channels to the reaction zone, and an outgoing path from the reaction zone to an exhaust channel. The incoming path and the outgoing path extend in alternating concentric spirals with the incoming path being countercurrent to the outgoing path. |
| FILED | Thursday, May 18, 2017 |
| APPL NO | 15/598512 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/2013 (20130101) Original (OR) Class F01N 3/2033 (20130101) F01N 2270/04 (20130101) F01N 2330/32 (20130101) F01N 2560/02 (20130101) F01N 2900/0416 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557554 | Hamilton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Flowserve Management Company (Irving, Texas) |
| ASSIGNEE(S) | Flowserve Management Company (Irving, Texas) |
| INVENTOR(S) | Eric Hamilton (Wildomar, California); Daniel Nelson (Wildomar, California) |
| ABSTRACT | A secondary seal of a mechanical seal comprises an annular sealing gasket and backing plate surrounding a cylindrical sealing surface, all of which can be made of the same metallic material. The gasket is C-shaped in cross section, and is axially pressed during operation into a C-shaped groove formed in the backing plate, the groove being shallower and larger in inner diameter than the gasket, so that the gasket, when pressed into the groove, deforms radially inward and seals against both the backing plate and the sealing surface. The contact area between the gasket and sealing surface increases with pressure. In embodiments, when the pressure is released, the gasket retracts from the sealing surface, allowing easy disassembly and allowing axial movement of the gasket and backing plate. Highly polished surfaces of the gasket and sealing surface can allow axial motion thereof during operation to maintain the seal face gap. |
| FILED | Thursday, June 14, 2018 |
| APPL NO | 16/008214 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Pistons; Cylinders; Sealings F16J 15/38 (20130101) Original (OR) Class F16J 15/344 (20130101) F16J 15/363 (20130101) F16J 15/3452 (20130101) F16J 15/3464 (20130101) F16J 15/3472 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557949 | Rowland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Mark S Rowland (Livermore, California); Neal J Snyderman (Livermore, California) |
| ABSTRACT | A system discriminating fissile material from nonfissile material wherein a digital data acquisition unit collects data at high rate, and processes large volumes of data directly to count neutrons from the unknown source and detect excess grouped neutrons to identify fission. The system includes a Poisson neutron generator for in-beam interrogation of a possible fissile neutron source and inducing neutron emission therefrom, and a DC power supply that exhibits electrical ripple of less than one part per million. A neutron count histogram and Poisson count distribution are overlaid to provide a visual indication of the difference in correlation of natural and induced emitted neutrons from the radiation source to characterize the neutron source as fissile material or non-fissile material. |
| FILED | Monday, January 08, 2018 |
| APPL NO | 15/865062 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/005 (20130101) Measurement of Nuclear or X-radiation G01T 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557950 | Rowland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Mark S Rowland (Livermore, California); Neal J Snyderman (Livermore, California) |
| ABSTRACT | A method of discriminating fissile material from non-fissile material with a digital data acquisition system that collects data at high rate, and processes large volumes of data directly to count neutrons from the unknown source and detect excess grouped neutrons to identify fission. The system includes a Poisson neutron generator for in-beam interrogation of a possible fissile neutron source and inducing neutron emission therefrom, and a DC power supply that exhibits electrical ripple of less than one part per million. A neutron count histogram and Poisson count distribution are overlaid to provide a visual indication of the difference in correlation of natural and induced emitted neutrons from the radiation source to characterize the neutron source as fissile material or non-fissile material. |
| FILED | Monday, January 08, 2018 |
| APPL NO | 15/865099 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/005 (20130101) Measurement of Nuclear or X-radiation G01T 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10558418 | Dutu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Alexandru Dutu (Bellevue, Washington); Bradford M. Beckmann (Bellevue, Washington) |
| ABSTRACT | A technique for implementing synchronization monitors on an accelerated processing device (“APD”) is provided. Work on an APD includes workgroups that include one or more wavefronts. All wavefronts of a workgroup execute on a single compute unit. A monitor is a synchronization construct that allows workgroups to stall until a particular condition is met. Responsive to all wavefronts of a workgroup executing a wait instruction, the monitor coordinator records the workgroup in an “entry queue.” The workgroup begins saving its state to a general APD memory and, when such saving is complete, the monitor coordinator moves the workgroup to a “condition queue.” When the condition specified by the wait instruction is met, the monitor coordinator moves the workgroup to a “ready queue,” and, when sufficient resources are available on a compute unit, the APD schedules the ready workgroup for execution on a compute unit. |
| FILED | Thursday, July 27, 2017 |
| APPL NO | 15/661843 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 3/1431 (20130101) Original (OR) Class G06F 9/3855 (20130101) Image Data Processing or Generation, in General G06T 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10558606 | Das et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Shomit N. Das (Austin, Texas); Matthew Tomei (Champaign, Illinois); Shrikanth Ganapathy (Mountain View, California); John Kalamatianos (Arlington, Massachusetts) |
| ABSTRACT | Systems, apparatuses, and methods for reliably transmitting data over voltage scaled links are disclosed. A computing system includes at least first and second devices connected via a link. In one implementation, if a data block can be compressed to less than or equal to half the original size of the data block, then the data block is compressed and sent on the link in a single clock cycle rather than two clock cycles. If the data block cannot be compressed to half the original size, but if the data block can be compressed enough to include error correction code (ECC) bits without exceeding the original size, then ECC bits are added to the compressed block which is sent on the link at a reduced voltage. The ECC bits help to correct for any errors that are generated as a result of operating the link at the reduced voltage. |
| FILED | Thursday, August 30, 2018 |
| APPL NO | 16/118172 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/3296 (20130101) G06F 13/42 (20130101) Original (OR) Class Coding; Decoding; Code Conversion in General H03M 13/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10558618 | Bent et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EMC Corporation (Hopkinton, Massachusetts) |
| ASSIGNEE(S) | EMC IP Holding Company LLC (Hopkinton, Massachusetts); Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | John M. Bent (Los Alamos, New Mexico); Sorin Faibish (Newton, Massachusetts); Zhenhua Zhang (Beijing, China PRC); Jun He (Madison, Wisconsin); Aaron Torres (Seattle, Washington); Gary Grider (Los Alamos, New Mexico) |
| ABSTRACT | A computer-executable method, system, and computer program product for managing a Parallel-Logged File System (PLFS) on a data storage system, wherein the data storage system is in communication with an application that updates the data storage system with checkpoint data, the computer-executable method, system, and computer program product comprising receiving a first checkpoint including data from the application; analyzing the data in the first checkpoint to determine whether a pattern exists in the checkpoint data; and upon a positive determination, adding the pattern into PLFS. |
| FILED | Monday, September 30, 2013 |
| APPL NO | 14/041872 |
| ART UNIT | 2161 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/13 (20190101) G06F 16/1744 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559389 | Sterbentz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battell Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | James Sterbentz (Idaho Falls, Idaho); James E. Werner (Idaho Falls, Idaho) |
| ABSTRACT | A modular nuclear reactor comprises a plurality of sections arranged in a pattern and a side reflector material surrounding the plurality of sections. Each section includes a tank comprising a front plate, a back plate, side plates, a top plate, and a bottom plate. A plurality of grid plates are located within the tank. Each grid plate comprises a plurality of apertures and is vertically separated from an adjacent grid plate. The tank further includes a plurality of fuel elements extending through each grid plate. A plurality of heat pipes extend through each grid plate, the top plate, and an upper reflector. Methods of forming the modular nuclear reactor are also disclosed. |
| FILED | Monday, February 06, 2017 |
| APPL NO | 15/425414 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 3/16 (20130101) Original (OR) Class G21C 3/623 (20130101) G21C 15/257 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559431 | Ruther et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Rose E. Ruther (Oak Ridge, Tennessee); Frank M. Delnick (Maryville, Tennessee); Jagjit Nanda (Knoxville, Tennessee) |
| ABSTRACT | A supercapacitor according to the present invention includes a negative carbon-comprising electrode which does not intercalate sodium, and a positive carbon-comprising electrode. An electrolyte composition comprises sodium hexafluorophosphate and a non-aqueous solvent comprising at least one selected from the group consisting of ethylene glycol dimethyl ether, diethylene glycol dimethyl ether, triethylene glycol dimethyl ether, and tetraethylene glycol dimethyl ether. The supercapacitor has an electrochemical voltage window of from +0.0 V to 3.5 V (full cell voltage). The electrolyte has an electrochemical voltage window of from +0.05 V to 3.9 V vs. Na/Na+. A method of making and a method of operating a supercapacitor is also disclosed. |
| FILED | Wednesday, November 08, 2017 |
| APPL NO | 15/806693 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/04 (20130101) H01G 11/06 (20130101) H01G 11/24 (20130101) H01G 11/32 (20130101) H01G 11/38 (20130101) H01G 11/60 (20130101) Original (OR) Class H01G 11/62 (20130101) H01G 11/84 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559449 | Glaeser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Robert M. Glaeser (Berkeley, California); Bong-Gyoon Han (Castro Valley, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to arrangements including electron microscopy grids. In one aspect an arrangement includes an electron microscopy grid. The electron microscopy grid comprises a first surface and a second surface, with the first surface having a holey carbon film disposed thereon. A plurality of lipid molecules are disposed in a hole in the holey carbon film. Each lipid molecule of the plurality of lipid molecules has a hydrophilic head and a hydrophobic tail. A biotin-binding protein is attached to the hydrophilic heads of the plurality of lipid molecules. The biotin-binding protein is crystalline. |
| FILED | Monday, December 18, 2017 |
| APPL NO | 15/844854 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/20 (20130101) Original (OR) Class H01J 37/261 (20130101) H01J 2237/2007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559747 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Yufan Li (Baltimore, Maryland); Qinli Ma (Baltimore, Maryland); Chia-ling Chien (Cockeysville, Maryland) |
| ABSTRACT | A magneto-electronic device may include: a spin-orbit torque (SOT) generator layer; a magnetic memory layer; and/or sensing electrodes configured to measure a Hall effect of the magnetic memory layer. The SOT generator layer may include topological insulator material, and the magnetic memory layer may include ferromagnetic material with perpendicular magnetic anisotropy. A magneto-electronic device may include: a spin-orbit torque (SOT) generator layer; a first magnetic memory layer on the SOT generator layer; an insulating layer on the first magnetic memory layer; and/or a second magnetic memory layer on the insulating layer. The SOT generator layer may include topological insulator material. The first magnetic memory layer and the second magnetic memory layer may include ferromagnetic material with either perpendicular magnetic anisotropy or in-plane magnetic anisotropy. |
| FILED | Wednesday, April 26, 2017 |
| APPL NO | 15/497591 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/18 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/04 (20130101) H01L 43/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559977 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| INVENTOR(S) | Moon C. Kim (Glastonbury, Connecticut); Kaiyu Wang (Vernon, Connecticut); Stella M. Oggianu (West Hartford, Connecticut); Robert K. Thornton (Coventry, Connecticut); Yiqing Lin (Glastonbury, Connecticut) |
| ABSTRACT | A microgrid according to an exemplary aspect of the present disclosure includes, among other things, a plurality of intelligent electronic devices configured to communicate directly with one another in a first language. Each of the intelligent electronic devices includes a controller and a gateway. The gateway is configured to convert incoming messages from the first language to a second language native to the controller. The first language is different than the second language. A method is also disclosed. |
| FILED | Friday, July 10, 2015 |
| APPL NO | 15/737914 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/2614 (20130101) G05B 2219/2642 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 13/0062 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10560022 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| INVENTOR(S) | Wei Huang (Frisco, Texas); Miguel Rodriguez (Golden, Colorado); Karthik Rao (Austin, Texas) |
| ABSTRACT | An apparatus includes an integrated circuit chip with a set of circuits having two or more subsets of circuits; an external voltage regulator separate from the integrated circuit chip; two or more integrated voltage regulators on the integrated circuit chip that each provide an input voltage to a respective subset of the circuits; and a controller. The controller determines, using an integrated voltage regulator power loss model, an electrical power loss for the integrated voltage regulators for a first combination of operating points for the subsets of the circuits. The controller then determines, based on the electrical power loss, a second combination of operating points for the subsets of the circuits that includes an adjustment to an operating point for at least one of the subsets of the circuits that compensates for an electrical power loss of the corresponding integrated voltage regulator. The controller sets an operating point of each of the subsets of the circuits based on the second combination of operating points. |
| FILED | Thursday, June 13, 2019 |
| APPL NO | 16/440838 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Systems for Regulating Electric or Magnetic Variables G05F 1/56 (20130101) G05F 1/468 (20130101) G05F 1/575 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/1582 (20130101) Original (OR) Class H02M 2001/0022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10556804 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Quanbao Zhao (Pullman, Washington); Stephen W. Dvorak (Chilton, Wisconsin); Shulin Chen (Pullman, Washington); Craig Frear (Pullman, Washington); Bryan J. VanLoo (Lynden, Washington) |
| ASSIGNEE(S) | DVO, INC. (Chilton, Wisconsin); WASHINGTON STATE UNIVERSITY (Pullman, Washington); ANDGAR CORPORATION (Everett, Washington) |
| INVENTOR(S) | Quanbao Zhao (Pullman, Washington); Stephen W. Dvorak (Chilton, Wisconsin); Shulin Chen (Pullman, Washington); Craig Frear (Pullman, Washington); Bryan J. VanLoo (Lynden, Washington) |
| ABSTRACT | Methods, systems, and apparatuses for anaerobic digestion of waste fibrous material and the recovery of nutrients are provided. Methods, systems, and apparatuses disclosed herein provide mechanisms to release dissolved gases from anaerobic digester effluent. Methods, systems and apparatuses disclosed herein can recover one or more nutrients from anaerobic digested effluent using a range of temperatures, aeration rates, aeration times, pH ranges, and settling times. |
| FILED | Wednesday, December 18, 2013 |
| APPL NO | 14/133355 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0066 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/22 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10556839 | Temme et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pivot Bio, Inc. (Berkeley, California) |
| ASSIGNEE(S) | Pivot Bio, Inc. (Berkeley, California) |
| INVENTOR(S) | Karsten Temme (Oakland, California); Alvin Tamsir (San Francisco, California); Sarah Bloch (Oakland, California); Rosemary Clark (Emeryville, California); Emily Tung (Millbrae, California) |
| ABSTRACT | Disclosed herein are methods of increasing nitrogen fixation in a non-leguminous plant. The methods can comprise exposing the plant to a plurality of bacteria. Each member of the plurality comprises one or more genetic variations introduced into one or more genes or non-coding polynucleotides of the bacteria's nitrogen fixation or assimilation genetic regulatory network, such that the bacteria are capable of fixing atmospheric nitrogen in the presence of exogenous nitrogen. The bacteria are not intergeneric microorganisms. Additionally, the bacteria, in planta, produce 1% or more of the fixed nitrogen in the plant. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/954557 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Nitrogenous Fertilisers C05C 1/00 (20130101) C05C 1/00 (20130101) C05C 3/005 (20130101) C05C 3/005 (20130101) C05C 5/005 (20130101) C05C 5/005 (20130101) C05C 11/00 (20130101) C05C 11/00 (20130101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class C05F 11/08 (20130101) C05F 11/08 (20130101) C05F 11/08 (20130101) C05F 11/08 (20130101) Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/80 (20130101) C12N 9/93 (20130101) C12N 9/0095 (20130101) Enzymes C12Y 118/06001 (20130101) C12Y 305/01002 (20130101) C12Y 603/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557550 | Saindon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mide Technology Corporation (Medford, Massachusetts) |
| ASSIGNEE(S) | Mide Technology Corporation (Woburn, Massachusetts) |
| INVENTOR(S) | Luke Clovis Saindon (Somerville, Massachusetts); Noel Jared Keegan (Medford, Massachusetts); Marthinus van Schoor (Arlington, Massachusetts) |
| ABSTRACT | A constant volume flexible joint system includes a flexible membrane for coupling across a joint and spaced radial support ribs fitted to the membrane. Axial support structures are coupled to the spaced radial support ribs preventing axial deformation of the joint due to a differential pressure. The axial support structure preferably include pivoting sockets and blocks enabling the joint to flex and the flexible membrane to contract on the inside of a bend and expand by an equal or near equal amount on the outside of the bend resulting in a constant volume joint that requires low or no torque throughout the bending motion. |
| FILED | Thursday, April 07, 2016 |
| APPL NO | 15/092851 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 11/10 (20130101) Pistons; Cylinders; Sealings F16J 3/048 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 403/453 (20150115) Y10T 403/32622 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557789 | Prater et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bruker Nano, Inc. (Santa Barbara, California) |
| ASSIGNEE(S) | Bruker Nano, Inc. (Santa Barbara, California) |
| INVENTOR(S) | Craig Prater (Santa Barbara, California); Kevin Kjoller (Santa Barbara, California); Doug Gotthard (Santa Barbara, California); Qichi Hu (Camarillo, California) |
| ABSTRACT | Described are techniques for obtaining spectroscopic information from sub-micron regions of a sample using a probe microscope. The current invention uses the response of an AFM cantilever at a plurality of frequencies to substantially reduce the impact of background absorption away from the sub-micron region of interest. This innovation substantially improves the quality of spectra for top down illumination of samples that are not suitable for bottoms up illumination of the prior art. |
| FILED | Wednesday, July 31, 2013 |
| APPL NO | 13/956156 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/35 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559811 | Zhamu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, Gyeonggi-do, South Korea) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Gyeonggi-Do, South Korea) |
| INVENTOR(S) | Aruna Zhamu (Centerville, Ohio); Jinjun Shi (Hilliard, Ohio); Guorong Chen (Fairborn, Ohio); Qing Fang (Fairborn, Ohio); Bor Z. Jang (Centerville, Ohio) |
| ABSTRACT | A nano graphene-enhanced particulate for use as a lithium-ion battery anode active material, wherein the particulate is formed of a single sheet of graphene or a plurality of graphene sheets and a plurality of fine anode active material particles with a size smaller than 10 μm. The graphene sheets and the particles are mutually bonded or agglomerated into the particulate with at least a graphene sheet embracing the anode active material particles. The amount of graphene is at least 0.01% by weight and the amount of the anode active material is at least 0.1% by weight, all based on the total weight of the particulate. A lithium-ion battery having an anode containing these graphene-enhanced particulates exhibits a stable charge and discharge cycling response, a high specific capacity per unit mass, a high first-cycle efficiency, a high capacity per electrode volume, and a long cycle life. |
| FILED | Wednesday, January 11, 2017 |
| APPL NO | 15/403759 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/48 (20130101) H01M 4/131 (20130101) H01M 4/133 (20130101) Original (OR) Class H01M 4/139 (20130101) H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/0471 (20130101) H01M 4/483 (20130101) H01M 4/523 (20130101) H01M 4/587 (20130101) H01M 4/625 (20130101) H01M 4/5825 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10556804 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Quanbao Zhao (Pullman, Washington); Stephen W. Dvorak (Chilton, Wisconsin); Shulin Chen (Pullman, Washington); Craig Frear (Pullman, Washington); Bryan J. VanLoo (Lynden, Washington) |
| ASSIGNEE(S) | DVO, INC. (Chilton, Wisconsin); WASHINGTON STATE UNIVERSITY (Pullman, Washington); ANDGAR CORPORATION (Everett, Washington) |
| INVENTOR(S) | Quanbao Zhao (Pullman, Washington); Stephen W. Dvorak (Chilton, Wisconsin); Shulin Chen (Pullman, Washington); Craig Frear (Pullman, Washington); Bryan J. VanLoo (Lynden, Washington) |
| ABSTRACT | Methods, systems, and apparatuses for anaerobic digestion of waste fibrous material and the recovery of nutrients are provided. Methods, systems, and apparatuses disclosed herein provide mechanisms to release dissolved gases from anaerobic digester effluent. Methods, systems and apparatuses disclosed herein can recover one or more nutrients from anaerobic digested effluent using a range of temperatures, aeration rates, aeration times, pH ranges, and settling times. |
| FILED | Wednesday, December 18, 2013 |
| APPL NO | 14/133355 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0066 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/22 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557145 | Martin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH (Ithaca, New York) |
| ASSIGNEE(S) | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (Ithaca, New York) |
| INVENTOR(S) | Gregory B. Martin (Ithaca, New York); Sarah R. Hind (Ithaca, New York); Susan R. Strickler (Ithaca, New York) |
| ABSTRACT | One aspect of the present invention relates to a nucleic acid construct that includes a nucleic acid molecule that encodes FLAGELLIN-SENSING 3 (“FLS3”) protein; a 5′ heterologous DNA promoter sequence; and a 3′ terminator sequence, where the nucleic acid molecule, the DNA promoter sequence, and the terminator sequence are operatively coupled to permit transcription of the nucleic acid molecule. The present invention also relates to a method of imparting disease resistance to a plant. This method involves transforming a plant or a plant seed with a nucleic acid molecule that increases expression of an FLS3 protein, where said transforming is effective in imparting disease resistance to the transformed plant or to a transgenic plant produced from the transformed plant seed. The present invention also relates to methods of expressing a nucleic acid molecule in a plant, identifying a candidate plant suitable for breeding that displays enhanced disease resistance, and enhancing efficiency of transformation of a plant by Agrobacterium. |
| FILED | Wednesday, July 08, 2015 |
| APPL NO | 15/324389 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) C12N 15/8279 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) C12Q 2600/13 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10557918 | Chartier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Eric Chartier (St. Louis Park, Minnesota); Paul C. Davis (Saratoga, California); Ryan L. Hagelstrom (Chaska, Minnesota); Ian J. McLinden (Minneapolis, Minnesota); Douglas Sweet (Sunnyvale, California) |
| ABSTRACT | A method for establishing and controlling a mobile perimeter and for determining a geographic location of an emitting radio frequency (RF) emitter in a vicinity of the mobile perimeter includes at each of a plurality of RF sensors, receiving an RF transmission, processing the received RF transmission to produce RF signal data, and wirelessly transmitting the RF signal data to a central station. At the central station, a processor: executes a cross-correlation process to: compare characteristics of pairs of RF signal data; based on the compared characteristics, determine a time difference of arrival (TDOA) between RF transmissions received at each RF sensor of a pair of RF sensors, and repeats the cross-correlation process for each pair of RF sensors from which RF signal data are received. Using the TDOA values for two or more pairs of RF sensors, the processor determines a location estimate for the RF emitter. |
| FILED | Monday, July 22, 2019 |
| APPL NO | 16/518210 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/06 (20130101) Original (OR) Class G01S 5/0018 (20130101) G01S 5/021 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) H04L 67/18 (20130101) Wireless Communication Networks H04W 4/021 (20130101) H04W 4/40 (20180201) H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10555961 | Molitoris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana); United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana); UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Bruce A. Molitoris (Indianapolis, Indiana); Mark C. Wagner (Indianapolis, Indiana); Ruben M. Sandoval (Indianapolis, Indiana); Mark Gerard Goebl (Indianapolis, Indiana) |
| ABSTRACT | Various aspects relate to the use of C-1 gentamicin as an antibiotic effective for the treatment of a bacterial infection, a genetic disorder, or cancer in a subject. |
| FILED | Friday, June 03, 2016 |
| APPL NO | 15/579487 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/351 (20130101) A61K 31/7036 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10555987 | Schally et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida); U.S.A., REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida); U.S.A., REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Andrew Schally (Miami Beach, Florida); Joshua M. Hare (Miami Beach, Florida); Norman Block (Hollywood, Florida); Samirah Gomes (Miami Beach, Florida); Rosemeire M. Kanashiro-Takeuchi (Miami, Florida) |
| ABSTRACT | Disclosed herein are compositions of GHRH agonists and peptides, and methods to treat disorders, such as ischemia and reperfusion injury. In one embodiment, a method of treating a reperfusion injury in a subject in need may involve administering a therapeutically effective amount of at least one GHRH agonist peptide to the subject. In additional embodiment, a method of promoting vasculogenesis in a mammal may involve administering a therapeutically effective amount of at least one GHRH agonist peptide to the subject. In a further embodiment, a method of promoting differentiation of mesenchymal stem cells into endothelial cells may involve contacting mesenchymal stem cells with at least one GHRH agonist peptide. |
| FILED | Tuesday, November 21, 2017 |
| APPL NO | 15/820079 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10556666 | Sclafani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Anthony J. Sclafani (Alta Loma, California); Adam D. Grasch (Santa Monica, California); Christopher K. Droney (Long Beach, California); Neal A. Harrison (Lake Forest, California) |
| ABSTRACT | Disclosed herein is an aircraft that comprises a body, a wing, and a strut. The wing is coupled to and extends from the body. A strut inboard end portion is coupled to and extends from the body and a strut outboard end portion is coupled to and extends from an intermediate portion of the wing. The wing further comprises a first thinned portion adjacent the intermediate portion of the wing. An overall thickness of the first thinned portion of the wing decreases and increases in a spanwise direction along the wing. The strut further comprises a second thinned portion adjacent the outboard end portion of the strut. An overall thickness of the second thinned portion of the strut decreases and increases in a spanwise direction along the strut. |
| FILED | Friday, March 31, 2017 |
| APPL NO | 15/476089 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10560063 | Bundick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Steven N. Bundick (Pocomoke City, Maryland); Wei-Chung Huang (College Park, Maryland) |
| ABSTRACT | A method of constructing an amplifier circuit includes simulating an output of an amplifier device of the amplifier circuit over a range of impedances to yield a simulated maximum power and a simulated maximum power added efficiency at a particular frequency, fabricating a plurality of output matching networks and input matching networks with impedances above and below the impedances that yield the simulated maximum power and simulated maximum power added efficiency, empirically determining physical dimensions of an optimized output matching network and an optimized input matching network that result in actual impedances that provide an actual maximum power and maximum power added efficiency at the particular frequency, and coupling the optimized output matching network to an output of the amplifier device and coupling the optimized input matching network between an output of a driver circuit and an input of the amplifier device. |
| FILED | Wednesday, August 08, 2018 |
| APPL NO | 16/058796 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Amplifiers H03F 1/56 (20130101) H03F 3/19 (20130101) Original (OR) Class H03F 2200/387 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/38 (20130101) H03H 2007/386 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10558575 | Fleming, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kermin E. Fleming, Jr. (Hudson, Massachusetts); Kent D. Glossop (Merrimack, New Hampshire); Simon C. Steely, Jr. (Hudson, New Hampshire); Jinjie Tang (Acton, Massachusetts); Alan G. Gara (Palo Alto, California) |
| ABSTRACT | Systems, methods, and apparatuses relating to a configurable spatial accelerator are described. In one embodiment, a processor includes a core with a decoder to decode an instruction into a decoded instruction and an execution unit to execute the decoded instruction to perform a first operation; a plurality of processing elements; and an interconnect network between the plurality of processing elements to receive an input of a dataflow graph comprising a plurality of nodes, wherein the dataflow graph is to be overlaid into the interconnect network and the plurality of processing elements with each node represented as a dataflow operator in the plurality of processing elements, and the plurality of processing elements is to perform a second operation when an incoming operand set arrives at the plurality of processing elements. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/396402 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3005 (20130101) G06F 9/3016 (20130101) G06F 9/3802 (20130101) G06F 9/3861 (20130101) G06F 12/0842 (20130101) G06F 12/0862 (20130101) Original (OR) Class G06F 12/0875 (20130101) G06F 2212/62 (20130101) G06F 2212/452 (20130101) G06F 2212/602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10559058 | Riabov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Anton V. Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (Port Chester, New York); Octavian Udrea (Ossining, New York) |
| ABSTRACT | Techniques for translating graphical representations of domain knowledge are provided. In one example, a computer-implemented method comprises receiving, by a device operatively coupled to a processor, a graphical representation of domain knowledge. The graphical representation comprises information indicative of a central concept and at least one chain of events associated with the central concept. The computer-implemented method further comprises translating, by the device, the graphical representation into an artificial intelligence planning problem. The artificial intelligence planning problem is expressed in an artificial intelligence description language. The translating comprises parsing the graphical representation into groupings of terms. A first grouping of terms of the grouping of terms comprises an event from the at least one chain of events and a second grouping of terms of the grouping of terms comprises the information indicative of the central concept. The computer-implemented method also comprises validating, by the device, the artificial intelligence planning problem. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/296364 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 5/022 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 1/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10556746 | Arlt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Hans Arlt (Vienna, Virginia); Christopher R. Simpson (Olney, Maryland) |
| ABSTRACT | A pulley assembly for an automative machine and methods for adjusting the pulley assembly are disclosed. The pulley assembly may include a monolithic body, an actuation assembly, and a pulley. The monolithic body may define a recess extending from a first end surface toward a second end surface thereof. The recess may at least partially separate an upper portion of the monolithic body from a lower portion of the monolithic body. The actuation assembly may be operably coupled with the monolithic body and configured to apply a biasing force to the upper portion of the monolithic body to actuate the upper portion of the monolithic body towards or away from the lower portion of the monolithic body. The pulley may be rotatably coupled with the upper portion of the monolithic body such that the pulley moves when the upper portion of the monolithic body is actuated. |
| FILED | Wednesday, February 20, 2019 |
| APPL NO | 16/280688 |
| ART UNIT | 3651 — Material and Article Handling |
| CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 15/64 (20130101) Original (OR) Class B65G 23/06 (20130101) B65G 39/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10558941 | Dixon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Robert E. Dixon (Washington, District of Columbia); Ryan Luckay (Washington, District of Columbia) |
| ABSTRACT | A receptacle for detecting delivery and retrieval events has a door sensor, an item sensor, a scanner, and a control unit for operating the sensors, and transmitting the sensor information for processing and analysis. A system can determine whether an event was a delivery or retrieval event based on sensor information and item tracking information. A system can further include an item configured to interact with a computing device. |
| FILED | Wednesday, March 22, 2017 |
| APPL NO | 15/466475 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Household or Table Equipment A47G 29/141 (20130101) A47G 2029/145 (20130101) A47G 2029/146 (20130101) A47G 2029/149 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) G06K 19/06028 (20130101) G06K 2019/06253 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0836 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10555775 | Hoffman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian David Hoffman (Sunnyvale, California); David Q. Larkin (Menlo Park, California); Giuseppe Prisco (Mountain View, California); Guanghua G Zhang (San Jose, California); Rajesh Kumar (Sunnyvale, California) |
| ASSIGNEE(S) | Intuitive Surgical Operations, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Brian David Hoffman (Sunnyvale, California); David Q. Larkin (Menlo Park, California); Giuseppe Prisco (Mountain View, California); Guanghua G Zhang (San Jose, California); Rajesh Kumar (Sunnyvale, California) |
| ABSTRACT | Methods and system perform tool tracking during minimally invasive robotic surgery. Tool states are determined using triangulation techniques or a Bayesian filter from either or both non-endoscopically derived and endoscopically derived tool state information, or from either or both non-visually derived and visually derived tool state information. The non-endoscopically derived tool state information is derived from sensor data provided either by sensors associated with a mechanism for manipulating the tool, or sensors capable of detecting identifiable signals emanating or reflecting from the tool and indicative of its position, or external cameras viewing an end of the tool extending out of the body. The endoscopically derived tool state information is derived from image data provided by an endoscope inserted in the body so as to view the tool. |
| FILED | Monday, May 16, 2005 |
| APPL NO | 11/130471 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/04 (20130101) A61B 1/00193 (20130101) A61B 1/3132 (20130101) A61B 5/06 (20130101) A61B 5/061 (20130101) A61B 5/062 (20130101) A61B 5/725 (20130101) A61B 34/20 (20160201) Original (OR) Class A61B 34/30 (20160201) A61B 34/37 (20160201) A61B 90/36 (20160201) A61B 90/39 (20160201) A61B 90/361 (20160201) A61B 2034/102 (20160201) A61B 2034/2065 (20160201) A61B 2090/364 (20160201) A61B 2090/0818 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
| US 10556856 | Uhrich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Kathryn E. Uhrich (Riverside, California); Allison Faig (Madison, New Jersey) |
| ABSTRACT | The invention provides an antibacterial compound of formula I: or a salt thereof, as well as an antibacterial compound of formula II: or a salt thereof, wherein R1, R2, X, Y and n have any of the values defined in the specification. |
| FILED | Thursday, October 18, 2018 |
| APPL NO | 16/164517 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/42 (20130101) A61K 9/1272 (20130101) A61K 31/23 (20130101) A61K 31/23 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/005 (20130101) A61Q 19/10 (20130101) Acyclic or Carbocyclic Compounds C07C 233/47 (20130101) Original (OR) Class C07C 235/06 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) Technologies for Adaptation to Climate Change Y02A 50/401 (20180101) Y02A 50/473 (20180101) Y02A 50/475 (20180101) Y02A 50/478 (20180101) Y02A 50/481 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 10555466 | Gonyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daegan Gonyer (Madrid, New York); Shaun Jones (Colton, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daegan Gonyer (Madrid, New York); Shaun Jones (Colton, New York) |
| ABSTRACT | A growth system for growing vegetation is provided, and includes a plurality of modular growing units defining a vegetative zone; a plurality of lighting units including a lighting node for selectively emitting first and/or second wavelengths of light in the vegetative zone; an unpressurized reservoir for housing a fluid containing one or more nutrients; a nutrient feeding system for fluidly connecting each of the modular units to the reservoir in parallel; and a pump in fluid communication between the reservoir and the modular units. When a modular unit is connected to the respective quick connect valve, the nutrient feeding system directs the fluid to the modular unit, and when the modular unit is disconnected from the valve, the valve is configured for preventing the fluid from flowing from the reservoir through the valve, and the other modular units connected to the nutrient feeding system remain fluidly connected to the reservoir. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/376080 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 31/02 (20130101) Original (OR) Class Non-portable Lighting Devices; Systems Thereof; Vehicle Lighting Devices Specially Adapted for Vehicle Exteriors F21S 2/005 (20130101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 33/00 (20130101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2113/13 (20160801) F21Y 2115/10 (20160801) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/0872 (20130101) H05B 37/0218 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 60/216 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10555957 | Subbaiah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois, a body corporate and politic of the state of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of The University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Papasani V. Subbaiah (Chicago, Illinois); Poorna Yalagala (Chicago, Illinois); Sugasini Dhavamani (Chicago, Illinois) |
| ABSTRACT | Described herein are at least compounds and formulations that can be or contain a docosahexaenoic acid-lysophosphatidylcholine (DHA-LPC) and/or eicosapenteanoic acid-lysophosphatidylcholine (EPA-LPC). Also described herein are at least methods of making and using the compositions and formulations DHA-LPC and/or EPA-LPC. |
| FILED | Thursday, May 10, 2018 |
| APPL NO | 15/976481 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 31/661 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10558689 | Beller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles E. Beller (Baltimore, Maryland); Paul J. Chase, Jr. (Fairfax, Virginia); Michael Drzewucki (Woodbridge, Virginia); Edward G. Katz (Washington, District of Columbia); Christopher Phipps (Arlington, Virginia) |
| ABSTRACT | A method, computer system, and a computer program product for leveraging coherent question sequences is provided. The present invention may include receiving an initiating question. The present invention may include receiving a subsequent question. The present invention may include determining that the received subsequent question is not a rephrasing of the received initiating question. The present invention may also include determining that the received subsequent question is not beginning a new question topic based on determining that the received subsequent question is not a rephrasing of the received initiating question. The present invention may then include propagating a conversational context based on determining that that received subsequent question is not beginning a new question topic. The present invention may include generating and scoring an answer based on the propagated conversational context. The present invention may lastly include outputting the answer. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 15/814012 |
| ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 16/3329 (20190101) Original (OR) Class G06F 16/3334 (20190101) G06F 16/24522 (20190101) G06F 17/2795 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 11, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
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https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200211.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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