FedInvent™ Patents
Patent Details for Tuesday, February 25, 2020
This page was updated on Monday, March 27, 2023 at 06:01 AM GMT
Department of Health and Human Services (HHS)
| US 10568507 | Chung et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Jaebum Chung (Pasadena, California); Changhuei Yang (South Pasadena, California) |
| ABSTRACT | Certain embodiments pertain to pupil ptychography methods and systems. |
| FILED | Monday, June 12, 2017 |
| APPL NO | 15/620674 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) A61B 3/14 (20130101) Original (OR) Class A61B 3/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568522 | Khan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Shadab Khan (Lebanon, New Hampshire); Ryan Halter (Orford, New Hampshire) |
| ABSTRACT | A surgical vision system for imaging heat capacity and cooling rate of tissue has an infrared source configured to provide infrared light to tissue, the infrared light sufficient to heat tissue, and an infrared camera configured to provide images of tissue at infrared wavelengths. The system also has an image processing system configured to determine, from the infrared images of tissue, a cooling or heating rate at pixels of the images of tissue at infrared wavelengths and to display images derived from the cooling rate at the pixels. |
| FILED | Thursday, October 23, 2014 |
| APPL NO | 15/031826 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/04 (20130101) A61B 1/0005 (20130101) A61B 1/00009 (20130101) A61B 1/063 (20130101) A61B 1/128 (20130101) A61B 1/0638 (20130101) A61B 1/3132 (20130101) A61B 5/015 (20130101) A61B 5/0035 (20130101) A61B 5/0075 (20130101) A61B 5/0086 (20130101) Original (OR) Class A61B 5/6847 (20130101) A61B 2576/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568535 | Roberts et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | David W. Roberts (Lyme, New Hampshire); Keith D. Paulsen (Hanover, New Hampshire); Alexander Hartov (Enfield, New Hampshire); Songbai Ji (Hanover, New Hampshire); Xiaoyao Fan (Lebanon, New Hampshire) |
| ABSTRACT | A surgical guidance system has two cameras to provide stereo image stream of a surgical field; and a stereo viewer. The system has a 3D surface extraction module that generates a first 3D model of the surgical field from the stereo image streams; a registration module for co-registering annotating data with the first 3D model; and a stereo image enhancer for graphically overlaying at least part of the annotating data onto the stereo image stream to form an enhanced stereo image stream for display, where the enhanced stereo stream enhances a surgeon's perception of the surgical field. The registration module has an alignment refiner to adjust registration of the annotating data with the 3D model based upon matching of features within the 3D model and features within the annotating data; and in an embodiment, a deformation modeler to deform the annotating data based upon a determined tissue deformation. |
| FILED | Friday, December 02, 2016 |
| APPL NO | 15/367243 |
| ART UNIT | 2485 — Recording and Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0077 (20130101) A61B 5/0476 (20130101) A61B 5/0484 (20130101) Original (OR) Class A61B 2034/104 (20160201) A61B 2034/105 (20160201) A61B 2034/107 (20160201) A61B 2090/367 (20160201) Image Data Processing or Generation, in General G06T 3/0068 (20130101) G06T 7/33 (20170101) G06T 2207/10012 (20130101) G06T 2207/10064 (20130101) G06T 2207/10072 (20130101) G06T 2207/30016 (20130101) Pictorial Communication, e.g Television H04N 13/239 (20180501) H04N 13/257 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568537 | Halpern |
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| FUNDED BY |
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| APPLICANT(S) | Howard J. Halpern (Chicago, Illinois) |
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| INVENTOR(S) | Howard J. Halpern (Chicago, Illinois) |
| ABSTRACT | The present invention provides an apparatus and a corresponding method useful for electron paramagnetic resonance imaging, in situ and in vivo, using high-isolation transmit/receive (TX/RX) coils, which, in some embodiments, provide microenvironmental images that are representative of particular internal structures in the human body and spatially resolved images of tissue/cell protein signals responding to conditions (such as hypoxia) that show the temporal sequence of certain biological processes, and, in some embodiments, that distinguish malignant tissue from healthy tissue. In some embodiments, the TX/RX coils are in a surface, volume or surface-volume configuration. In some embodiments, the transmit coils are oriented to generate an RF magnetic field in directions substantially orthogonal to a static gradient field, and the receive coils are oriented to sense RF EPR signal in directions substantially orthogonal to the transmitted field and to the static field, to minimize coupling of the transmitted signal to the receive coils. |
| FILED | Tuesday, March 04, 2014 |
| APPL NO | 14/196982 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/60 (20130101) G01R 33/341 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568634 | Goldie et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vivonics, Inc. (Bedford, Massachusetts) |
| ASSIGNEE(S) | Vivonics, Inc. (Bedford, Massachusetts) |
| INVENTOR(S) | James H. Goldie (Lexington, Massachusetts); Brendan LaBrecque (Middleton, Massachusetts); Anna M Galea (Stow, Massachusetts); Eric Klem (Lexington, Massachusetts); Thomas Doyle (Brentwood, Tennessee); Ian Cohen (Cambridge, Massachusetts); Tim Robinson (Sandown, New Hampshire) |
| ABSTRACT | A pulmonary artery flow restrictor system includes a funnel shaped membrane with a proximal base and a restrictive distal opening which is stretchable to larger sizes. A self-expanding frame is attached to the proximal base of the membrane for securing the membrane within the pulmonary artery. |
| FILED | Tuesday, January 31, 2017 |
| APPL NO | 15/420772 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/12036 (20130101) Original (OR) Class A61B 17/12109 (20130101) A61B 17/12172 (20130101) A61B 17/12177 (20130101) A61B 2017/12054 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/82 (20130101) A61F 2002/068 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 29/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568687 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Med-X institute Shanghai Jiao Tong University (Shanghai, China PRC) |
| ASSIGNEE(S) | The Regents of the University of California (Oaklan, California); Med-X institute Shanghai Jiao Tong University (Shanghai, China PRC) |
| INVENTOR(S) | Zhongping Chen (Irvine, California); Gangjun Liu (Irvine, California); Jiawen Li (Irvine, California); Lisa X. Xu (Shanghai, China PRC); Aili Zhang (Shanghai, China PRC) |
| ABSTRACT | A multimodal medical device for the diagnosis and/or thermal treatment of a disease includes an instrument for performing thermal therapy; and an imaging system having multiple tomographic imaging modes, including optical coherence tomography (OCT), ultrasound imaging, photoacoustic (PA) imaging, fluorescence imaging and/or thermal imaging to provide guidance for accurate diagnosis and treatment of the disease. |
| FILED | Friday, January 15, 2016 |
| APPL NO | 14/997204 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/0071 (20130101) A61B 5/0095 (20130101) A61B 8/08 (20130101) A61B 18/245 (20130101) A61B 18/1492 (20130101) Original (OR) Class A61B 18/1815 (20130101) A61B 2018/0212 (20130101) A61B 2018/00345 (20130101) A61B 2018/00577 (20130101) A61B 2018/00982 (20130101) A61B 2018/1807 (20130101) A61B 2018/1861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568840 | Karp et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Jeffrey Karp (Brookline, Massachusetts); Nitin Joshi (Quincy, Massachusetts); Xueyin He (Ontario, Canada); Sachin Bhagchandani (Cambridge, Massachusetts) |
| ABSTRACT | A self-assembled gel composition with enhanced adhesion to cartilage tissue is provided. A cationic agent co-self assembles with a generally regarded as safe (GRAS), low molecular weight (<2,500 Da) gelator, forming homogeneous self-supporting gel that can encapsulate one or more therapeutic agents for controlled release. The composition adheres to connective tissue, e.g., cartilage, to a greater extent and a greater length of time than a self-assembled gel from gelators alone. The composition is used to specifically target connective tissue and deliver one or more therapeutic, prophylactic, or diagnostic agents for controlled release to improve dosing efficacy. |
| FILED | Monday, May 08, 2017 |
| APPL NO | 15/589891 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 9/70 (20130101) A61K 9/4833 (20130101) Original (OR) Class A61K 9/5015 (20130101) A61K 31/10 (20130101) A61K 31/40 (20130101) A61K 31/55 (20130101) A61K 31/167 (20130101) A61K 31/245 (20130101) A61K 31/437 (20130101) A61K 31/495 (20130101) A61K 31/7024 (20130101) A61K 31/7028 (20130101) A61K 47/14 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568844 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yunfeng Lu (Culver City, California); Irvin S. Y. Chen (Palos Veerdes Estate, California); Ming Yan (Encino, California); Min Liang (Encino, California); Masakazu Kamata (Los Angeles, California); Jing Wen (Culver City, California) |
| ABSTRACT | Novel siRNA and shRNA nanocapsules and delivery methods are disclosed herein. These siRNA and shRNA nanocapsules and delivery methods are highly robust and effective. This invention provides a platform for RNAi delivery with low toxicity and long intracellular half-life for practical therapeutic applications. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 15/721501 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) Original (OR) Class A61K 9/5138 (20130101) A61K 9/5192 (20130101) A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 47/14 (20130101) A61K 47/18 (20130101) A61K 47/20 (20130101) A61K 47/22 (20130101) A61K 47/42 (20130101) A61K 47/6925 (20170801) A61K 47/6933 (20170801) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/111 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568851 | Palczewski et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Krzysztof Palczewski (Bay Village, Ohio); Yu Chen (Mayfield Heights, Ohio) |
| ABSTRACT | A method of treating an ocular disorder in a subject includes administering to the subject a therapeutically effective amount of an agent that modulates at least one target in a signaling cascade associated with light induced retinal degeneration, aberrant all-trans-retinal accumulation, and/or generation of reactive oxygen species (ROS). |
| FILED | Friday, April 25, 2014 |
| APPL NO | 14/262141 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/52 (20130101) A61K 31/155 (20130101) Original (OR) Class A61K 31/454 (20130101) A61K 31/475 (20130101) A61K 31/495 (20130101) A61K 31/505 (20130101) A61K 31/517 (20130101) A61K 31/4164 (20130101) A61K 31/4178 (20130101) A61K 31/4453 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568854 | Bjornsson et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Hans Tomas Bjornsson (Baltimore, Maryland); Harry Dietz (Towson, Maryland); Joel Benjamin (Baltimore, Maryland) |
| ABSTRACT | A method is provided for treating a Mendelian disorder of the epigenetic machinery (e.g., Kabuki syndrome) in a subject in need thereof. In particular, the method comprises administering to the subject a ketogenic composition in an amount sufficient to produce a physiologically acceptable ketosis in the subject. A method for selecting a subject for treatment of a Mendelian disorder of the epigenetic machinery (e.g., Kabuki syndrome) is also provided. Ketogenic compositions and kits useful for practicing the methods are also provided. |
| FILED | Friday, May 29, 2015 |
| APPL NO | 15/315172 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/30 (20160801) A23L 33/40 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) Original (OR) Class A61K 31/20 (20130101) A61K 31/23 (20130101) A61K 31/55 (20130101) A61K 31/166 (20130101) A61K 31/167 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/64 (20130101) G01N 2800/52 (20130101) G01N 2800/7033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568857 | Yang |
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| FUNDED BY |
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| APPLICANT(S) | The University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | The University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Tianxin Yang (Salt Lake City, Utah) |
| ABSTRACT | Methods of treating the side effects of a toxic medical therapy using nitrated lipids are disclosed herein. In particular, the methods comprise the use of nitrated fatty acids or esters thereof to treat side effects, including organ system damage, caused by chemotherapy, radiotherapy, and the administration of other toxic agents. |
| FILED | Thursday, June 20, 2019 |
| APPL NO | 16/447821 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/201 (20130101) Original (OR) Class A61K 31/231 (20130101) A61K 31/704 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568869 | Robinson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Brian Robinson (New York, New York); Jonathan Zippin (New York, New York) |
| ABSTRACT | The invention is directed to a method of inhibiting prostate cancer cell proliferation using a substance that inhibits the activity of a soluble adenylyl cyclase (sAC) protein. The invention also is directed to methods of diagnosing and prognosticating prostate cancer in a subject by evaluating sAC gene or protein expression in the subject. |
| FILED | Wednesday, December 11, 2013 |
| APPL NO | 14/650193 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4184 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57434 (20130101) G01N 2333/988 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568883 | Karp et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Jeffrey M. Karp (Brookline, Massachusetts); Robert S. Langer (Newton, Massachusetts); Xiaolei Yin (Quincy, Massachusetts); Nitin Joshi (Boston, Massachusetts) |
| ABSTRACT | Method and compositions for inducing the self-renewal of stem/progenitor supporting cells comprised by a cochlear cell population, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells. |
| FILED | Thursday, September 03, 2015 |
| APPL NO | 14/845263 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0046 (20130101) A61K 31/19 (20130101) A61K 31/19 (20130101) A61K 31/55 (20130101) A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/422 (20130101) A61K 31/422 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/506 (20130101) A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 31/5377 (20130101) A61K 31/5517 (20130101) A61K 31/5517 (20130101) A61K 33/00 (20130101) A61K 33/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0627 (20130101) C12N 2501/11 (20130101) C12N 2501/105 (20130101) C12N 2501/115 (20130101) C12N 2501/727 (20130101) C12N 2501/999 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568886 | Straub et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Adam C. Straub (Pittsburgh, Pennsylvania); Carlos J. Camacho (Pittsburgh, Pennsylvania); Mizanur Rahaman (Pittsburgh, Pennsylvania); Fabio Reinders (Gramsbergen, Netherlands) |
| ABSTRACT | A method for regulating arterial vascular tone in a subject, comprising administering to a subject in need thereof, a therapeutically effective amount of a compound, or a pharmaceutically acceptable salt thereof, having a structure of: wherein A and B are each individually selected from O or S; a is 1 to 4; and Ar is optionally substituted aryl or optionally substituted heteroaryl. |
| FILED | Friday, September 11, 2015 |
| APPL NO | 15/510636 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/513 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568889 | Ganesh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Thota Ganesh (Alpharetta, Georgia); Jianxiong Jiang (Cincinnati, Ohio); Ray J. Dingledine (Norcross, Georgia) |
| ABSTRACT | The disclosure relates to Prostaglandin receptor EP2 antagonists, derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing conditions and diseases in which EP2 receptor activation has a physiological role, such as but not limited to, brain injury, inflammatory diseases, neuroinflamation after a seizure, pain, endometriosis, cancer, rheumatoid arthritis, skin inflammation, vascular inflammation, colitis, and neurological disorders by administering a pharmaceutical composition comprising a compound disclosed herein to a subject in need thereof. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/037374 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/551 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4192 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568895 | Miller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Jordan D. Miller (Rochester, Minnesota); Bin Zhang (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials involved in treating cardiovascular conditions such as calcific aortic valve stenosis. For example, methods and materials for using sGC agonists or a combination of sGC agonists and PDE5A inhibitors to reduce calcification of heart valves and/or vessels or to slow progression of aortic sclerosis to calcific aortic valve stenosis are provided. |
| FILED | Thursday, February 07, 2019 |
| APPL NO | 16/269628 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/197 (20130101) A61K 31/197 (20130101) A61K 31/416 (20130101) A61K 31/416 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/635 (20130101) Original (OR) Class A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 31/5377 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568908 | O'Reilly et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Richard John O'Reilly (Roxbury, Connecticut); Susan Elizabeth Prockop (New York, New York); Aisha Nasreen Hasan (Blue Bell, Pennsylvania); Ekaterina Doubrovina (Bronx, New York) |
| ABSTRACT | The invention relates to methods of treating an EBV-LPD (Epstein-Barr Virus-associated lymphoproliferative disorder) in a human patient who has failed combination chemotherapy to treat the EBV-LPD and/or radiation therapy to treat the EBV-LPD, comprising administering to the human patient a population of allogeneic T cells comprising EBV-specific T cells. |
| FILED | Wednesday, May 11, 2016 |
| APPL NO | 15/572557 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568911 | Crawford et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Keith D. Crawford (Westwood, Massachusetts); Christopher Southgate (Sudbury, Massachusetts) |
| ABSTRACT | The invention provides a quiescent stem cell having the capacity to differentiate into ectoderm, mesoderm and endoderm, and which does not express cell surface markers including MHC class I, MHC class II, CD44, CD45, CD13, CD34, CD49c, CD73, CD105, CD90, CD66A, CD66E, CXCR4, CD133 or an SSEA. The invention further provides a proliferative stem cell, which expresses genes including Oct-4, Nanog, Sox2, GDF3, P16INK4, BMI, Notch, HDAC4, TERT, Rex-1, TWIST, KLF-4 and Stella but does not express cell surface markers including MHC class I, MHC class II, CD44, CD45, CD13, CD34, CD49c, CD73, CD105, CD90, CD66A, CD66E, CXCF4, CD133 or an SSEA. The cells of the invention can be isolated from adult mammals, have embryonic cell characteristics, and can form embryoid bodies. Methods for obtaining the stem cells, as well as methods of treating diseases and differentiating the stem cells, are also provided. |
| FILED | Thursday, July 13, 2017 |
| APPL NO | 15/648738 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/14 (20130101) A61K 35/24 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) C12N 5/0639 (20130101) C12N 5/0647 (20130101) C12N 5/0653 (20130101) C12N 5/0654 (20130101) C12N 5/0655 (20130101) C12N 5/0657 (20130101) C12N 5/0658 (20130101) C12N 5/0661 (20130101) C12N 5/0662 (20130101) C12N 5/0668 (20130101) C12N 5/0676 (20130101) C12N 2500/25 (20130101) C12N 2500/36 (20130101) C12N 2500/38 (20130101) C12N 2501/11 (20130101) C12N 2501/22 (20130101) C12N 2501/26 (20130101) C12N 2501/39 (20130101) C12N 2501/40 (20130101) C12N 2501/41 (20130101) C12N 2501/105 (20130101) C12N 2501/125 (20130101) C12N 2501/135 (20130101) C12N 2501/155 (20130101) C12N 2501/235 (20130101) C12N 2501/999 (20130101) C12N 2501/2303 (20130101) C12N 2501/2306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568912 | Anversa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AAL Scientifics, Inc. (New York, New York) |
| ASSIGNEE(S) | AAL Scientifics, Inc. (New York, New York) |
| INVENTOR(S) | Piero Anversa (New York, New York); Annarosa Leri (New York, New York) |
| ABSTRACT | Disclosed herein are methods, compositions and kits for treating cardiac stem cells to be administered to a subject in need thereof, e.g., with a damaged myocardium. The methods, composition and kits of the invention can be used to treat cardiovascular diseases such as heart failure, myocardial infarction and an age-related cardiomyopathy. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804339 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/34 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 5/0662 (20130101) C12N 2501/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568928 | Hawiger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Jack J. Hawiger (Nashville, Tennessee); Jozef Zienkiewicz (Nashville, Tennessee) |
| ABSTRACT | The present invention relates to compositions and methods for treating autoimmune, microbial, metabolic, neoplastic, and posttraumatic diseases mediated by inflammation in a subject. Compositions and methods including at least one importin beta-selective nuclear transport modifier (NTM) and/or at least one importin alpha-selective NTM, and/or at least one importin alpha-specific NTM, and/or at least one inhibitor of importin alpha and importin beta complex formation may be administered to a subject to modulate the transport of transcription factors, mediated by nuclear import adaptors, into the nucleus of a cell resulting in a decrease or abrogation of inflammation. |
| FILED | Wednesday, October 19, 2016 |
| APPL NO | 15/297996 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 38/12 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 38/16 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/47 (20130101) C07K 14/50 (20130101) C07K 14/4702 (20130101) C07K 2319/00 (20130101) C07K 2319/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568929 | Antalis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Toni Antalis (Potomac, Maryland); Erik Martin (Baltimore, Maryland) |
| ABSTRACT | Engineered anthrax protective antigen (PrAg) proteins are provided wherein the native furin activation site is replaced by the activation site of a membrane-anchored serine protease. These engineered PrAg proteins retain the ability to bind to cell surface PrAg receptors and be proteolytically activated. The proteins also retain the ability to form membrane pores. These engineered PrAg proteins can be used in methods of inducing pore formation in a cell, methods of inducing translocation of a selected compound or co-factor into a cell, and methods of treating disease, such as cancer, in a subject. |
| FILED | Friday, August 19, 2016 |
| APPL NO | 15/747255 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/51 (20130101) A61K 38/164 (20130101) Original (OR) Class A61K 38/4886 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Peptides C07K 14/32 (20130101) C07K 16/38 (20130101) C07K 2319/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568945 | Lentsch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Alex B. Lentsch (Hebron, Kentucky); Michael J. Edwards (Cincinnati, Ohio); Erich Gulbins (Cincinnati, Ohio) |
| ABSTRACT | A pharmaceutical composition containing (1) a therapeutically effective amount of hepatocyte-derived exosomes; and (2) a pharmaceutically-acceptable carrier is provided. Also provided herein is a method of inducing liver regeneration in a patient in need thereof, the method including administering to the patient a therapeutic amount of hepatocyte-derived exosomes, wherein liver regeneration is induced. Methods for up-regulating synthesis of synthesis of sphingosine-1-phosphate (S1P) in a hepatocyte by contacting the hepatocyte with at least one vesicle containing sphingosine kinase 2, and, optionally, ceramide and neutral ceramidase, are also disclosed. |
| FILED | Monday, April 27, 2015 |
| APPL NO | 14/696531 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/164 (20130101) A61K 38/45 (20130101) A61K 38/50 (20130101) Original (OR) Class Enzymes C12Y 207/01091 (20130101) C12Y 305/01023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568949 | Ali et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, inc. (Boston, Massachusetts) |
| INVENTOR(S) | Omar Abdel-Rahman Ali (Cambridge, Massachusetts); Glenn Dranoff (Sudbury, Massachusetts); David J. Mooney (Sudbury, Massachusetts) |
| ABSTRACT | The present invention comprises compositions, methods, and devices for creating an stimulating an antigen-specific dendritic cell immune response. Devices and methods provide prophylactic and therapeutic immunity to subjects against cancer and infectious agents. |
| FILED | Monday, November 20, 2017 |
| APPL NO | 15/818509 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/708 (20130101) A61K 31/4745 (20130101) A61K 31/7088 (20130101) A61K 38/193 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2039/54 (20130101) A61K 2039/6093 (20130101) A61K 2039/55516 (20130101) A61K 2039/55522 (20130101) A61K 2039/55561 (20130101) A61K 2039/55588 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568956 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the U.S.A. as rep. by the Secretary of the Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Gwong-Jen J. Chang (Fort Collins, Colorado); Wayne D. Crill (Boulder, Colorado); Holly R. Hughes (Fort Collins, Colorado); Brent S. Davis (Fort Collins, Colorado) |
| ABSTRACT | Described herein are dengue virus E-glycoprotein polypeptides containing mutations that eliminate immunodominant cross-reactive epitopes associated with immune enhancement. The disclosed dengue virus E-glycoproteins optionally further include mutations that introduce a strong CD4 T cell epitope. The disclosed E-glycoprotein polypeptides, or nucleic acid molecules encoding the polypeptides, can be used, for example, in monovalent or tetravalent vaccines against dengue virus. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/107119 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/57 (20130101) A61K 2039/70 (20130101) A61K 2039/575 (20130101) A61K 2039/5258 (20130101) A61K 2039/6031 (20130101) A61K 2039/6075 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24122 (20130101) C12N 2770/24123 (20130101) C12N 2770/24134 (20130101) C12N 2770/24151 (20130101) C12N 2770/24171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568963 | Pandey et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ravindra K. Pandey (East Amherst, New York); Raoul Kopelman (Ann Arbor, Michigan); Anurag Gupta (Hamburg, New York); Munawwar Sajjad (Clarence Center, New York) |
| ASSIGNEE(S) | HEALTH RESEARCH, INC. (Buffalo, New York); HE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (Amherst, New York); REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Ravindra K. Pandey (East Amherst, New York); Raoul Kopelman (Ann Arbor, Michigan); Anurag Gupta (Hamburg, New York); Munawwar Sajjad (Clarence Center, New York) |
| ABSTRACT | A composition comprising PAA nanoparticles containing a post loaded tetrapyrollic photosensitizer and a postloaded imaging agent and methods for making and using same. |
| FILED | Friday, August 03, 2012 |
| APPL NO | 13/566411 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0057 (20130101) Original (OR) Class A61K 41/0071 (20130101) A61K 47/6933 (20170801) A61K 49/0002 (20130101) A61K 49/0032 (20130101) A61K 49/0052 (20130101) A61K 49/0093 (20130101) A61K 51/0451 (20130101) A61K 51/1244 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568969 | Totrov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York); MOLSOFT LLC (San Diego, California); ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York); Molsoft LLC (San Diego, California); Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Maxim Totrov (San Diego, California); Xunqing Jiang (Brooklyn, New York); Ruimin Pan (New York, New York); Susan Zolla-Pazner (New York, New York); Xiangpeng Kong (New York, New York) |
| ABSTRACT | The present invention relates to isolated immunogenic polypeptides and their use. In one aspect, the isolated immunogenic polypeptide includes a scaffold polypeptide having a hairpin loop modified to include one or more epitopes heterologous to the scaffold polypeptide and from an amino acid loop linked by a disulfide bond. The scaffold polypeptide directs self-assembly with two other of the scaffold polypeptides to form a trimeric structure, which constrains the one or more epitopes to a conformation that is (i) substantially similar to one or more native pathogen epitopes in trimeric conformation and (ii) capable of binding an antibody reactive to the one or more native pathogen epitopes in trimeric conformation. Another aspect relates to an isolated immunogenic polypeptide that includes a scaffold polypeptide having a native loop modified to include one or more epitopes heterologous to the scaffold polypeptide and from an amino acid loop linked by a disulfide bond. The scaffold polypeptide directs self-assembly with four other of said scaffold polypeptides to form a pentameric structure, which constrains the one or more epitopes to a conformation capable of binding an antibody reactive to one or more native pathogen epitopes. |
| FILED | Tuesday, September 05, 2017 |
| APPL NO | 15/695753 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 39/385 (20130101) A61K 47/64 (20170801) A61K 47/646 (20170801) Original (OR) Class A61K 47/6415 (20170801) A61K 2039/70 (20130101) A61K 2039/575 (20130101) A61K 2039/6037 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) Peptides C07K 2319/30 (20130101) C07K 2319/35 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) Technologies for Adaptation to Climate Change Y02A 50/484 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568974 | Rogers et al. |
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| FUNDED BY |
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| APPLICANT(S) | Exemplar Genetics, LLC (Sioux Center, Iowa) |
| ASSIGNEE(S) | EXEMPLAR GENETICS LLC (Sioux Center, Iowa) |
| INVENTOR(S) | Christopher S Rogers (North Liberty, Iowa); John R Swart (Orange City, Iowa) |
| ABSTRACT | The present invention provides transgenic, large non-human animal models of atherosclerosis and hypercholesterolemia, as well as methods of using such animal models in the identification and characterization of therapies for atherosclerosis and hypercholesterolemia. |
| FILED | Sunday, September 23, 2012 |
| APPL NO | 13/624967 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 2217/075 (20130101) A01K 2227/108 (20130101) A01K 2267/0362 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568975 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Tao Yu (Baltimore, Maryland); Himatkumar Patel (Baltimore, Maryland); Kannie M. Y. Chan (Baltimore, Maryland); Nikita Oskolkov (Reisterstown, Maryland); Michael McMahon (Columbia, Maryland); Justin Hanes (Baltimore, Maryland) |
| ABSTRACT | Surface conjugated diamagnetic Chemical Exchange Saturation Transfer (diaCEST) agent carriers and methods of making and using are described herein. The particles are safe alternatives to conventional paramagnetic or superparamagnetic metal-based MRI contrast agents that are often toxic and therefore not biocompatible. The carriers described herein can provide simultaneous monitoring of multiple particle types labeled with ‘multicolor’ diaCEST contrast agents. In some embodiments, the carriers are micro- and/or nanoparticles. In other embodiments, the carriers are liposomes. In some embodiments, the particles and/or liposomes are mucus penetrating. In other embodiments, the particles and/or liposomes are not mucus penetrating. |
| FILED | Wednesday, February 05, 2014 |
| APPL NO | 14/765881 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/1833 (20130101) A61K 49/1878 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568985 | Runge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael Brett Runge (Pine Island, Minnesota); Michael J. Yaszemski (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Michael Brett Runge (Pine Island, Minnesota); Michael J. Yaszemski (Rochester, Minnesota) |
| ABSTRACT | A polycaprolactone fumarate copolymer useful as a material for a biocompatible scaffold for tissue engineering applications is disclosed. The copolymer includes at least one caprolactone unit, at least one fumarate unit, and at least one third unit selected from the group consisting of acrylate units and styrenic units. A linking moiety forms a link between the third unit and at least one caprolactone unit or at least one fumarate unit. The linking moiety can be photodegradable. In one form, the third unit includes at least one methyl methacrylate unit. The copolymer can be used to form the wall of a nerve conduit. |
| FILED | Wednesday, July 31, 2013 |
| APPL NO | 13/955279 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) Original (OR) Class A61L 27/56 (20130101) A61L 2430/32 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/08 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569082 | Shore et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Susan Shore (Ann Arbor, Michigan); David Martel (Ann Arbor, Michigan); Seth Koehler (Baltimore, Maryland) |
| ABSTRACT | Timed stimulation of both somatosensory system and auditory system is controlled, in such a manner, that an individual's brain activity is altered through spike-timing dependent plasticity, thereby reducing or removing tinnitus. |
| FILED | Monday, June 19, 2017 |
| APPL NO | 15/627358 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/128 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 11/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/02 (20130101) A61M 2021/0027 (20130101) A61M 2021/0072 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36 (20130101) Original (OR) Class A61N 1/361 (20130101) A61N 1/36036 (20170801) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 25/75 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569104 | El Fakhri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Georges El Fakhri (Brookline, Massachusetts); Nathaniel Alpert (Plymouth, Massachusetts); Xuping Zhu (Malden, Massachusetts); Kira Grogg (Somerville, Massachusetts) |
| ABSTRACT | The present disclosure provides a system and method for method for quantifying radioactivity production during a proton treatment of a patient. In some aspects, a method includes administering, using a proton delivery system, a proton treatment using at least one therapeutic proton beam generating positron emitting radionuclides within a region of interest (ROI) of a patient, and acquiring, using an emission tomography system, emission tomography data indicative of an activity of the positron emitting radionuclides in the ROI. The method also includes quantifying, based on a kinetic model, a radioactivity production rate of at least one positron emitting radionuclide using the emission tomography data. The method further includes generating at least one map indicative of the radioactivity production rate of the at least one positron emitting radionuclide. |
| FILED | Monday, April 11, 2016 |
| APPL NO | 15/095827 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1071 (20130101) Original (OR) Class A61N 2005/1052 (20130101) A61N 2005/1087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569125 | Schindler-Ivens et al. |
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| FUNDED BY |
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| APPLICANT(S) | Marquette University (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | Marquette University (Milwaukee, Wisconsin) |
| INVENTOR(S) | Sheila Schindler-Ivens (Shorewood, Wisconsin); Brian D. Schmit (Brookfield, Wisconsin); Domenic Busa (Madison, Wisconsin) |
| ABSTRACT | Split-crank pedaling devices and methods of operation support patient use and rehabilitation, particularly for stroke patients. A split-crank pedaling device includes first and second crank assemblies. First and second motors are operably connected to the first and second crank assemblies. A first shaft sensor produces an indication of a position of the shaft of the first crank assembly. A second shaft sensor produces an indication of a position of the shaft of the second crank assembly. A controller is communicatively connected to the first and second motors and the first and second shaft sensors and calculates a phase error between the positions of the first and second shafts and a predetermined phase relationship between the first and second shafts. The controller operates at least one of the first motor or the second motor to provide a supplemental torque to one of the first crank assembly and the second crank assembly. |
| FILED | Thursday, May 03, 2018 |
| APPL NO | 15/970503 |
| ART UNIT | 3784 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 22/0017 (20151001) A63B 22/0025 (20151001) A63B 22/0605 (20130101) Original (OR) Class A63B 2022/0038 (20130101) A63B 2022/0094 (20130101) A63B 2022/0617 (20130101) A63B 2220/16 (20130101) A63B 2220/34 (20130101) A63B 2220/44 (20130101) A63B 2220/54 (20130101) A63B 2230/045 (20130101) A63B 2230/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569261 | Malcolmson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON COLLEGE (Chestnut Hill, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston College (Chestnut Hill, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Steven J. Malcolmson (Brighton, Massachusetts); Amir H. Hoveyda (Lincoln, Massachusetts); Simon J. Meek (Newtonville, Massachusetts); Richard R. Schrock (Winchester, Massachusetts) |
| ABSTRACT | The present invention provides compositions comprising metal complexes, and related methods. In some embodiments, metal complexes of the invention may be useful as catalysts for chemical reactions, including metathesis reactions, wherein the catalysts exhibit enhanced activity and stereoselectivity. In some embodiments, the invention may advantageously provide metal complexes comprising a stereogenic metal atom. Such metal complexes may be useful in enantioselective catalysis. |
| FILED | Tuesday, June 06, 2017 |
| APPL NO | 15/615644 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/181 (20130101) B01J 31/1805 (20130101) Original (OR) Class B01J 31/2208 (20130101) B01J 31/2265 (20130101) B01J 2231/54 (20130101) B01J 2531/64 (20130101) B01J 2531/66 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 11/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570077 | Donaldson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Marquette University (Milwaukee, Wisconsin); Concordia University, Inc. (Mequon, Wisconsin) |
| ASSIGNEE(S) | Marquette University (Milwaukee, Wisconsin); Concordia University Inc. (Mequon, Wisconsin) |
| INVENTOR(S) | William A. Donaldson (Milwaukee, Wisconsin); Daniel S. Sem (New Berlin, Wisconsin); Terrence S. Neumann (Milwaukee, Wisconsin) |
| ABSTRACT | Disclosed are substituted (4′-hydroxylphenyl)cycloalkane compounds and there use as selective agonists of the estrogen receptor beta isoform (ERβ). The disclosed compounds may be formulated as pharmaceutical compositions and administered to treat diseases associated with ER activity, such as proliferative diseases and disorders and/or psychiatric diseases or disorders. |
| FILED | Monday, May 23, 2016 |
| APPL NO | 15/162057 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 39/17 (20130101) Original (OR) Class C07C 39/23 (20130101) C07C 59/54 (20130101) C07C 69/732 (20130101) C07C 251/44 (20130101) C07C 2601/14 (20170501) C07C 2601/18 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570103 | Beaton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EPIGEN BIOSCIENCES, INC. (San Diego, California) |
| ASSIGNEE(S) | EPIGEN BIOSCIENCES, INC. (San Diego, California) |
| INVENTOR(S) | Graham Beaton (San Diego, California); Fabio C. Tucci (San Diego, California); Satheesh B. Ravula (San Diego, California); Chandravadan R. Shah (San Diego, California); Hiep Luu (San Marcos, California) |
| ABSTRACT | A method for treating a lysophosphatidic acid-dependent disease or condition in a subject in need thereof is provided. The method includes administering to the subject a therapeutically effective amount of a heterocyclic compound. The heterocyclic compound is a lysophosphatidic acid receptor ligand. Lysophosphatidic acid-dependent diseases and conditions include diseases involving fibrosis, such as fibrosis of the heart, kidney, liver and lung, and scleroderma; inflammatory diseases such as diabetic nephropathy and inflammatory bowel disease; ocular diseases such as diseases involving retinal degeneration; nerve diseases such as pruritus and pain. |
| FILED | Tuesday, June 05, 2018 |
| APPL NO | 16/000283 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/415 (20130101) Heterocyclic Compounds C07D 231/38 (20130101) C07D 231/52 (20130101) C07D 233/88 (20130101) C07D 239/42 (20130101) C07D 261/14 (20130101) Original (OR) Class C07D 263/48 (20130101) C07D 401/04 (20130101) C07D 413/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570104 | Bergeron, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainsville, Florida) |
| INVENTOR(S) | Raymond J. Bergeron, Jr. (Gainesville, Florida) |
| ABSTRACT | The present invention provides compounds of Formula (I), which are “metabolically programmed” metal chelators, e.g., lipophilic, absorbable (e.g., orally absorbable), and effective metal chelators that are converted in vivo to their hydrophilic, nontoxic metabolites. The present invention also provides compounds of Formula (II), which are also “metabolically programmed” metal chelators. The invention also provides pharmaceutical compositions, kits, methods, and uses that include a compound described herein. The compounds, pharmaceutical compositions, kits, and methods may be useful in treating or preventing a disease (e.g., metal overload, oxidative stress, diabetes, liver disease, heart disease, cancer, radiation injury, neurological or neurodegenerative disorder, Friedreich's ataxia (FRDA), macular degeneration, closed head injury, irritable bowel disease, reperfusion injury, metal poisoning, or infectious disease). |
| FILED | Wednesday, April 27, 2016 |
| APPL NO | 15/569750 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) Acyclic or Carbocyclic Compounds C07C 211/54 (20130101) C07C 215/50 (20130101) C07C 229/16 (20130101) Heterocyclic Compounds C07D 277/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570124 | Radu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Caius G. Radu (Los Angeles, California); Raymond M. Gipson (Los Angeles, California) |
| ABSTRACT | There are provided, inter alia, compounds useful for binding to deoxycytidine kinase, and compounds and methods useful to modulate deoxycytidine kinase. |
| FILED | Monday, January 09, 2017 |
| APPL NO | 16/068658 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 417/12 (20130101) Original (OR) Class C07D 417/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570146 | Makriyannis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Alexandros Makriyannis (Watertown, Massachusetts); Vidyanand G Shukla (Boston, Massachusetts); Shakiru O Alapafuja (Willimantic, Connecticut) |
| ABSTRACT | Disclosed are compounds that may be used to inhibit the action of fatty acid amide hydrolase (FAAH), monoacylglycerol lipase (MAGL) or dual FAAH/MAGL. More particularly, compounds of formula II have utility in a variety of therapeutic uses such as treatment of pain, inflammation, neuropathy, or appetite disorder. |
| FILED | Friday, July 24, 2015 |
| APPL NO | 15/328428 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 205/04 (20130101) C07D 211/16 (20130101) C07D 211/46 (20130101) C07D 211/54 (20130101) C07D 213/64 (20130101) C07D 213/74 (20130101) C07D 213/84 (20130101) C07D 213/85 (20130101) C07D 215/12 (20130101) C07D 233/61 (20130101) C07D 241/04 (20130101) C07D 257/04 (20130101) C07D 295/26 (20130101) C07D 295/195 (20130101) C07D 401/06 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/06 (20130101) C07D 405/06 (20130101) C07D 487/08 (20130101) C07D 491/107 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570148 | Petrukhin et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University In the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Konstantin Petrukhin (New Windsor, New York); Christopher Cioffi (Troy, New York); Graham Johnson (Sanbornton, New Hampshire); Nicoleta Dobri (New York, New York); Emily Freeman (Voorheesville, New York); Ping Chen (Slingerlands, New York); Michael Conlon (Schenectady, New York); Lei Zhu (Glenmont, New York) |
| ABSTRACT | The present invention provides a compound having the structure: (structurally represented) wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl; R6 is alkyl; A is absent or present, and when present is —C(O)— or —C(O)NH—; B is substituted or unsubstituted monocycle, bicycle, heteromonocycle, heterobicycle, benzyl, CO2H or (C1-C4 alkyl)-CO2H, wherein when B is CO2H, then A is present and is —C(O)—, or a pharmaceutically acceptable salt thereof. |
| FILED | Tuesday, April 03, 2018 |
| APPL NO | 15/944334 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/56 (20130101) Heterocyclic Compounds C07D 213/79 (20130101) C07D 213/80 (20130101) C07D 231/56 (20130101) C07D 237/24 (20130101) C07D 239/28 (20130101) C07D 249/04 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 491/052 (20130101) C07D 498/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570150 | Rao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Jianghong Rao (Sunnyvale, California); Haibin Shi (Mountain View, California) |
| ABSTRACT | The present invention discloses a probe useful for the selective detection of metallo-beta-lactamases, in particular carbapenemases, thereby distinguishing those species of bacteria that are carbapenem-resistant from bacterial strains that are sensitive. Cephalospori based probes that have the 6,7 R,R configuration are susceptible to cleavage by beta-lactamases but cannot distinguish between cleavage by metallo-beta-lactamases and other beta-lactamases. By modifying a side group of the cephalosporin, selectivity can be introduced allowing the probes to distinguish between various types of metallo-beta-lactamases. |
| FILED | Thursday, January 15, 2015 |
| APPL NO | 15/111576 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 277/64 (20130101) C07D 311/16 (20130101) C07D 501/00 (20130101) Original (OR) Class C07D 501/26 (20130101) C07D 501/48 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) C12Q 1/66 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/986 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570173 | Bogyo et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Matthew S. Bogyo (Redwood City, California); Martijn Verdoes (Nijmegen, Netherlands); Leslie Ofori (Jupiter, Florida); Nimali P. Withana (Menlo Park, California) |
| ABSTRACT | Compounds useful as contrast agents in image-guided surgery are provided. The compounds comprise a latent cationic lysosomotropic fragment that is detectable upon cleavage by lysosomal proteases within treated tissues, particularly within tumors and other diseased tissues. Also provided are compositions comprising the compounds and methods for using the compounds, for example in dynamically monitoring protease activity in vivo during image-guided tumor resection surgery. |
| FILED | Friday, January 22, 2016 |
| APPL NO | 15/545689 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0056 (20130101) A61K 51/08 (20130101) Peptides C07K 5/06086 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570179 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Richard E. Lee (Cordova, Tennessee); Ying Zhao (Memphis, Tennessee) |
| ABSTRACT | In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, September 01, 2017 |
| APPL NO | 16/329168 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/15 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 11/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570183 | Olson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Eric N. Olson (University Park, Texas); Rhonda S. Bassel-Duby (Dallas, Texas); Catherine A. Makarewich (Dallas, Texas); Benjamin R. Nelson (Dallas, Texas) |
| ABSTRACT | The present disclosure describes a new native peptide designated herein as Dwarf Open Reading Frame, or DWORF. This peptide enhances the apparent activity of the SERCA pump, is positively inotropic and lusitropic, and therefore is provided as a therapeutic agent for disorders characterized by cytosolic calcium overload. |
| FILED | Wednesday, April 19, 2017 |
| APPL NO | 15/491057 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 45/06 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570200 | Hay et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Bruce A. Hay (Pasadena, California); Juan Li (Pasadena, California) |
| ABSTRACT | The present disclosure generally relates to methods and compositions for contraception. In some embodiments, vector based approaches for contraception are provided. |
| FILED | Friday, January 31, 2014 |
| APPL NO | 14/170118 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 16/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570204 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novartis AG (Basel, Switzerland); The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin); Novartis AG (Basel, Switzerland) |
| INVENTOR(S) | Bryon Duane Johnson (Jackson, Wisconsin); Robert Millman (Boston, Massachusetts) |
| ABSTRACT | The present invention relates to methods of treating hematologic cancers using a combination of inhibitors of PD-1 or PD-L1 and TIM-3, LAG-3 or CTLA-4. In one embodiment, an inhibitor of PD-1 or PD-L1 is administered in combination with an inhibitor of TIM-3. In another embodiment, an inhibitor of PD-1 or PD-L1 is administered in combination with an inhibitor of LAG-3. In yet another embodiment, an inhibitor of PD-1 or PD-L1 is administered in combination with an inhibitor of CTLA-4. |
| FILED | Thursday, September 25, 2014 |
| APPL NO | 15/024396 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/1096 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Peptides C07K 16/2803 (20130101) C07K 16/2827 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) C07K 2317/626 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570207 | Scadden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | David T. Scadden (Weston, Massachusetts); Rahul Palchaudhuri (Cambridge, Massachusetts); Derrick J. Rossi (Newton, Massachusetts); Agnieszka D. Czechowicz (Boston, Massachusetts) |
| ABSTRACT | Disclosed herein are non-myeloablative antibody-toxin conjugates and compositions that target cell surface markers, such as the CD34, CD45 or CD117 receptors, and related methods of their use to effectively conditioning a subject's tissues (e.g., bone marrow tissue) prior to engraftment or transplant. The compositions and methods disclosed herein may be used to condition a subject's tissues in advance of, for example, hematopoietic stem cell transplant and advantageously such compositions and methods do not cause the toxicities that are commonly associated with traditional conditioning methods. |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/205205 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 38/164 (20130101) A61K 38/168 (20130101) A61K 47/6825 (20170801) A61K 47/6849 (20170801) A61K 47/6898 (20170801) Peptides C07K 4/04 (20130101) C07K 16/289 (20130101) C07K 16/2866 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) G01N 33/56966 (20130101) G01N 33/57407 (20130101) G01N 33/57434 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570208 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAYLOR RESEARCH INSTITUTE (Dallas, Texas) |
| ASSIGNEE(S) | Baylor Research Institute (Dallas, Texas) |
| INVENTOR(S) | Yong-Jun Liu (Gaithersburg, Maryland); Sandra Zurawski (Midlothian, Texas); SangKon Oh (Baltimore, Maryland); Shino Hanabuchi (Gaithersburg, Maryland); Haruyuki Fujita (Gaithersburg, Maryland); Hideki Ueno (Plano, Texas); Patrick Blanco (Verdelais, France); Hyemee Joo (Dallas, Texas) |
| ABSTRACT | Described herein are methods and compositions for treating autoimmunity and inflammatory conditions without non-specific suppression of the host immune system. In particular, the anti-OX40L antibodies described herein are unique in that they not only inhibit the differentiation of inflammatory T cells but also promote the generation and function of regulatory T cells by inducing IL-10 and inhibiting TNF-α and by reducing aberrant Th2 cell responses. Furthermore, the methods and compositions described herein eliminate or reduce aberrant T follicular helper cell—(Tfh) responses that may contribute to the pathogenicity of autoimmune disease. |
| FILED | Wednesday, December 05, 2018 |
| APPL NO | 16/210188 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) A61K 2039/545 (20130101) Peptides C07K 16/2875 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570214 | Morgan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Richard A. Morgan (Columbia, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | The invention provides chimeric antigen receptors (CARs) comprising an antigen binding domain of human antibody 139, an extracellular hinge domain, a transmembrane domain, and an intracellular domain T cell receptor signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a host and methods of treating or preventing cancer in a host are also disclosed. |
| FILED | Friday, March 03, 2017 |
| APPL NO | 15/448707 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70575 (20130101) C07K 14/70578 (20130101) C07K 14/70596 (20130101) C07K 16/32 (20130101) Original (OR) Class C07K 16/2863 (20130101) C07K 16/3053 (20130101) C07K 2317/21 (20130101) C07K 2319/00 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/30 (20130101) C07K 2319/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/71 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570216 | Roberts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BioVentures, LLC (Little Rock, Arkansas); Arkansas Children's Research Institute (Little Rock, Arkansas) |
| ASSIGNEE(S) | BioVentures, LLC (, Arkansas); Arkansas Children's Research Institute (Little Rock, Arkansas) |
| INVENTOR(S) | Dean W. Roberts (Little Rock, Arkansas); Laura James (Little Rock, Arkansas); Jack Hinson (Little Rock, Arkansas) |
| ABSTRACT | The present disclosure provides isolated antibodies that bind to acetaminophen-protein adducts that are useful in the detection and diagnosis of acetaminophen-induced toxicity. |
| FILED | Thursday, December 03, 2015 |
| APPL NO | 15/532418 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/44 (20130101) Original (OR) Class C07K 19/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/9486 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570374 | Singh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Ankur Singh (Ithaca, New York); Shalu Suri (Ithaca, New York); Todd Christopher McDevitt (Atlanta, Georgia); Hang Lu (Atlanta, Georgia); Andres Jose Garcia (Atlanta, Georgia) |
| ABSTRACT | The present invention provides for methods of isolating a stem cell or cell derived therefrom from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/148784 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0623 (20130101) C12N 5/0696 (20130101) Original (OR) Class C12N 2506/45 (20130101) C12N 2509/10 (20130101) C12N 2527/00 (20130101) C12N 2539/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570375 | Singh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Ankur Singh (Ithaca, New York); Shalu Suri (Ithaca, New York); Todd Christopher McDevitt (Atlanta, Georgia); Hang Lu (Atlanta, Georgia); Andres Jose Garcia (Atlanta, Georgia) |
| ABSTRACT | The present invention provides for methods of isolating a stem cell or cell derived therefrom from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/149918 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0623 (20130101) C12N 5/0696 (20130101) Original (OR) Class C12N 2506/45 (20130101) C12N 2509/10 (20130101) C12N 2527/00 (20130101) C12N 2539/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570381 | Paul |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Surojit Paul (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Surojit Paul (Albuquerque, New Mexico) |
| ABSTRACT | A novel peptide sequence that is a modified derivative of a neuron-specific tyrosine phosphatase is shown and described. Specifically, the novel peptide sequence is a modified derivative of striatal-enriched tyrosine phosphatase (STEP). The peptide sequence has been modified so as to be able to ameliorate and treat brain injury resulting from excessive glutamate release and/or oxidative stress. Examples of the types of brain injury which the presently disclosed peptide sequence is useful for treating includes acute brain injury resulting from stroke or traumatic brain injury and chronic disorders such as Huntington's chorea and schizophrenia. Furthermore, the presently described peptide sequence may further be useful in the treatment and amelioration of disorders associated with fear memory such as post-traumatic stress disorder. |
| FILED | Wednesday, August 29, 2018 |
| APPL NO | 16/116117 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/465 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/03048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570392 | Orkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Stuart H. Orkin (Brookline, Massachusetts); Vijay G. Sankaran (Jamaica Plain, Massachusetts) |
| ABSTRACT | The invention relates to methods and uses of modulating fetal hemoglobin expression (HbF) in a hematopoietic progenitor cells via inhibitors of BCL11A expression or activity, such as RNAi and antibodies. |
| FILED | Thursday, February 14, 2019 |
| APPL NO | 16/275534 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/15 (20130101) A01K 2217/052 (20130101) A01K 2227/105 (20130101) A01K 2267/0381 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 35/28 (20130101) A61K 49/00 (20130101) Peptides C07K 14/805 (20130101) C07K 14/4705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/8509 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2740/15043 (20130101) C12N 2800/206 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570398 | Goel et al. |
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| FUNDED BY |
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| APPLICANT(S) | BAYLOR RESEARCH INSTITUTE (Dallas, Texas) |
| ASSIGNEE(S) | Baylor Research Institute (Dallas, Texas) |
| INVENTOR(S) | Ajay Goel (Dallas, Texas); Kunitoshi Shigeyasu (Dallas, Texas) |
| ABSTRACT | Certain embodiments provide methods and compositions related to clinical management of cancer patients based on the expression level of TMCO3. Further embodiments involve methods and compositions related to treatment of cancer patients or patients determined to have an increased TMCO3 level relative to a control or a reference level that is normal or indicating favorable prognosis. |
| FILED | Thursday, March 17, 2016 |
| APPL NO | 15/559362 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Peptides C07K 16/28 (20130101) C07K 16/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57419 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570400 | Lajoie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Marc J. Lajoie (Cambridge, Massachusetts); Christopher J. Gregg (Roslindale, Massachusetts); Joshua A. Mosberg (Cambridge, Massachusetts); George M. Church (Brookline, Massachusetts) |
| ABSTRACT | A method of introducing a nucleic acid sequence into a cell is provided where the cell has impaired or inhibited or disrupted DnaG primase activity or impaired or inhibited or disrupted DnaB helicase activity, or larger or increased gaps or distance between Okazaki fragments or lowered or reduced frequency of Okazaki fragment initiation, or the cell has increased single stranded DNA (ssDNA) on the lagging strand of the replication fork including transforming the cell through recombination with a nucleic acid oligomer. |
| FILED | Tuesday, February 07, 2017 |
| APPL NO | 15/426527 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) C12N 15/72 (20130101) Original (OR) Class C12N 15/102 (20130101) C12N 15/1024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570416 | Rayner et al. |
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| FUNDED BY |
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| APPLICANT(S) | ALPHAVAX, INC. (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | ALPHAVAX, INC. (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Jon O. Rayner (Hoover, Alabama); Jonathan F. Smith (Cary, North Carolina); Bolyn Hubby (Chapel Hill, North Carolina); Elizabeth A. Reap (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides TC-83 VEE-derived replicons, alphaviral replicon particles and immunogenic compositions containing TC-83 alphaviral replicon particles which direct the expression of at least one antigen when introduced into a suitable host cell. The TC-83 VEE-derived ARPs described herein are improved in that they are subject to a lower vector-specific immune response than prior art ARPs. |
| FILED | Thursday, August 11, 2016 |
| APPL NO | 15/234949 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 48/00 (20130101) A61K 2039/575 (20130101) A61K 2039/5256 (20130101) A61K 2039/5258 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2740/16222 (20130101) C12N 2740/16234 (20130101) C12N 2770/36123 (20130101) C12N 2770/36134 (20130101) C12N 2770/36143 (20130101) C12N 2770/36152 (20130101) C12N 2770/36162 (20130101) C12N 2840/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570417 | Wunderlich et al. |
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| FUNDED BY |
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| APPLICANT(S) | Janssen Vaccines and Prevention B.V. (Leiden, Netherlands) |
| ASSIGNEE(S) | Janssen Vaccines and Prevention B.V. (Leiden, Netherlands) |
| INVENTOR(S) | Kerstin Wunderlich (Kassel, Germany); Jerôme H. H. V. Custers (Alphen aan den Rijn, Netherlands); Jort Vellinga (Voorschoten, Netherlands); Barbara Petronella Sanders (Amsterdam, Netherlands) |
| ABSTRACT | The invention provides recombinant adenovirus (rAd) and rAd vectors comprising a bidirectional mouse CMV (mCMV) promoter operably linked to a first transgene in one direction and to a second transgene in the opposite direction. The invention also provides methods of making and using such rAd and rAd vectors. |
| FILED | Tuesday, April 12, 2016 |
| APPL NO | 15/566073 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2710/10343 (20130101) C12N 2760/14134 (20130101) C12N 2760/14234 (20130101) C12N 2830/42 (20130101) C12N 2830/205 (20130101) C12N 2840/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570438 | Krueger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Immunetics, Inc. (Marlborough, Massachusetts) |
| ASSIGNEE(S) | Immunetics, Inc. (Marlborough, Massachusetts) |
| INVENTOR(S) | Neil X. Krueger (Roslindale, Massachusetts); Andrew Han (Cambridge, Massachusetts); Andrew E. Levin (Wellesley, Massachusetts); Victor Kovalenko (Saco, Maine) |
| ABSTRACT | The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-β-D-glucan in a sample. |
| FILED | Friday, January 26, 2018 |
| APPL NO | 15/880903 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) C12Q 1/22 (20130101) C12Q 1/26 (20130101) Original (OR) Class C12Q 2304/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/25 (20130101) G01N 21/255 (20130101) G01N 33/56911 (20130101) G01N 2333/195 (20130101) G01N 2333/43552 (20130101) G01N 2333/90245 (20130101) G01N 2400/24 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570442 | Gimzewski et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | James K. Gimzewski (Topanga, California); Bhubaneswar Mishra (New York, New York); Jason C. Reed (Richmond, Virginia) |
| ABSTRACT | The present invention provides methods of detecting a nucleic acid analyte in a sample. The methods generally involve modifying immobilized nucleic acids from a sample onto an insoluble support in a substantially elongated configuration, where modification generates an identifying feature that identifies the analyte; and detecting the identifying feature(s) using scanning probe microscopy, to detect the analyte. The present invention further provides a method for assigning a profile of a feature to a nucleic acid. The present invention further provides a computer program product for use in a subject method. The present invention further provides a system for detecting a nucleic acid in a sample; and a system for assigning a profile of a feature to a nucleic acid. The present invention further provides a method for immobilizing a nucleic acid onto an insoluble support; and further provides insoluble support having nucleic acid(s) immobilized thereon. The present invention further provides a method of diagnosing a disorder or condition in an individual, where the method involves use of a subject method for detecting a nucleic acid analyte. |
| FILED | Tuesday, September 24, 2013 |
| APPL NO | 14/035734 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/683 (20130101) C12Q 1/683 (20130101) C12Q 1/6834 (20130101) Original (OR) Class C12Q 1/6834 (20130101) C12Q 2521/331 (20130101) C12Q 2521/331 (20130101) C12Q 2522/101 (20130101) C12Q 2565/518 (20130101) C12Q 2565/601 (20130101) C12Q 2565/601 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570444 | Wanunu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Meni Wanunu (Boston, Massachusetts); Joseph Larkin (Dorchester, Massachusetts); Robert Henley (Boston, Massachusetts) |
| ABSTRACT | Devices and methods useful for sequencing and characterizing single nucleic acid molecules involve large arrays of nanopore zero-mode waveguides (NZMWs). The methods and devices are made possible by fabrication of nanoporous membranes of appropriate porosity for use in nucleotide sequencing. The fabrication methods eliminate the need for serial nanopore formation and make possible the mass production of highly efficient DNA and RNA single molecule sequencing devices. |
| FILED | Wednesday, May 11, 2016 |
| APPL NO | 15/572296 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570451 | Salk et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
| ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/120019 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570454 | Brody et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts); University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts); University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Jerome S. Brody (Boston, Massachusetts); Avrum Spira (Newton, Massachusetts); Adam Gustafson (Portland, Oregon); Andrea Bild (Salt Lake City, Utah) |
| ABSTRACT | The invention provides the identification of oncogenic pathways activated in cytologically normal airway cells of individuals having or at risk of having lung disease, as well as specific gene expression patterns (biomarkers) associated with pathway activation. These biomarkers and pathways may provide prognostic and/or diagnostic indicators in lung disease, e.g., lung cancer. Additionally, these pathways and biomarkers may provide therapeutic targets for the treatment of lung disease, as well as markers for the assessment of treatment efficacy. |
| FILED | Monday, September 29, 2014 |
| APPL NO | 14/500475 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/047 (20130101) A61K 31/5377 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) C12Q 1/6809 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/91205 (20130101) G01N 2800/50 (20130101) G01N 2800/7028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570455 | Su et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Sheng-Fang Su (Los Angeles, California); Gangning Liang (Los Angeles, California); Peter Jones (Los Angeles, California); Kimberly Siegmund (Los Angeles, California) |
| ABSTRACT | A method for the prediction, prognosis and/or diagnosis of bladder cancer or bladder cancer recurrence in a subject, the method includes: providing a test sample from the subject; measuring DNA methylation levels of at least a portion of two or more polynucleotides selected from the group consisting of HOXA9, SOXI, NPY, IRAK3, L1-MET, and Z02 in the test sample; calculating a risk score based on the measured DNA methylation levels, comparing the calculated risk score to a cut-off value derived from a reference DNA methylation profile based on DNA methylation levels of the one or more biomarkers derived from a control group, members of which had bladder cancer; and based on the comparison calculated risk score to the cut-off value, determining at least one of: (1) whether bladder cancer has recurred; (2) whether there is likelihood that the bladder cancer will recur; and (3) whether the patient has bladder cancer. |
| FILED | Friday, May 09, 2014 |
| APPL NO | 14/890424 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570460 | Luo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Jianhua Luo (Wexford, Pennsylvania); Yangping Yu (Wexford, Pennsylvania); Joel B. Nelson (Pittsburgh, Pennsylvania); George Konstantine Michalopoulos (Pittsburgh, Pennsylvania); Chien-Cheng Tseng (Pittsburgh, Pennsylvania); Ying Ding (San Diego, California) |
| ABSTRACT | The present invention relates to methods and compositions for determining whether a subject having prostate cancer is at greater risk of developing progressive disease, and methods of treating the subjects. It is based, at least in part, on the discovery that approximately 90% of men carrying at least one of the following fusion genes: TRMT11-GRIK2, SLC45A2-AMACR, MTOR-TP53BP1, LRRC59-FLJ60017, TMEM135-CCDC67 and CCNH-05orf30 experienced prostate cancer recurrence, metastases and/or prostate cancer-specific death after radical prostatectomy (each examples of “progressive prostate cancer”), while these outcomes occurred in only 36% of men not carrying any of these fusion genes. It is also based, at least in part, on the discovery that no patient studied survived five years without recurrence if their primary prostate cancer contained a TRMT11-GRIK2 or MTOR-TP53BP1 fusion gene. It is also based, at least in part, on the discovery that the protein encoded by the MAN2A1-FER fusion gene exhibits kinase activity. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/185372 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570464 | Andini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Nadya Andini (Fremont, California); Samuel S. Yang (Burlingame, California) |
| ABSTRACT | Methods and oligonucleotide reagents for identification of bacteria by high resolution melting (HRM) analysis are described. In particular, the invention relates to HRM analysis of hypervariable bacterial genomic DNA of the internal transcribed spacer (ITS) region for fingerprinting eubacterial pathogens. |
| FILED | Monday, May 08, 2017 |
| APPL NO | 15/589392 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6816 (20130101) C12Q 1/6851 (20130101) C12Q 1/6851 (20130101) C12Q 2563/159 (20130101) C12Q 2600/156 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) G06N 20/00 (20190101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) G16B 30/10 (20190201) G16B 40/00 (20190201) G16B 40/20 (20190201) G16B 40/30 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571371 | Marini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WAKE FOREST UNIVERSITY HEALTH SCIENCES (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | WAKE FOREST UNIVERSITY HEALTH SCIENCES (Winston-Salem, North Carolina) |
| INVENTOR(S) | Frank Marini (Winston-Salem, North Carolina); George Christ (Winston-Salem, North Carolina) |
| ABSTRACT | The disclosure provides improved materials and methods for optically clearing biological tissue that is subsequently used for deep tissue imaging analysis. Also provided is a description of a microscopic image acquisition methodology in which imagery of intact tissues are acquired to rapidly acquire microscopy data on a whole-organ scale to maximize cost effectiveness for biological microscopy and minimize time spent performing such analysis. |
| FILED | Friday, August 07, 2015 |
| APPL NO | 15/502081 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) Original (OR) Class G01N 1/36 (20130101) G01N 1/4044 (20130101) G01N 33/4833 (20130101) G01N 2001/364 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571373 | Halden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolf U. Halden (Phoenix, Arizona); Isaac B. Roll (Tempe, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Rolf U. Halden (Phoenix, Arizona); Isaac B. Roll (Tempe, Arizona) |
| ABSTRACT | A method and system for enabling the determination of kinetic rates of reaction within a fluid of interest including directing fluid flow exiting a test bed to a multi-port switching valve. The multi-port switching valve switches the fluid to a number of channels connected to a number of interchangeable in-flow extraction cartridges. Analytes of interest from the fluid flow are captured on an extraction medium to accumulate over time. Rates are determined by (i) sequentially channeling the fluid through each of the plurality of flow paths for a preselected time duration, (ii) analyzing the extraction cartridges, and computing the kinetic rate of reaction. |
| FILED | Thursday, May 11, 2017 |
| APPL NO | 15/593152 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/08 (20130101) B01D 15/14 (20130101) B01D 24/40 (20130101) B01D 35/26 (20130101) B01D 36/02 (20130101) B01D 53/025 (20130101) B01D 61/58 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/444 (20130101) Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 1/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 1/14 (20130101) G01N 1/16 (20130101) G01N 1/18 (20130101) G01N 1/405 (20130101) Original (OR) Class G01N 5/02 (20130101) G01N 15/0631 (20130101) G01N 33/186 (20130101) G01N 33/1893 (20130101) G01N 2001/1031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571428 | Ramsey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | John Michael Ramsey (Chapel Hill, North Carolina); Laurent Menard (Raleigh, North Carolina) |
| ABSTRACT | Devices and methods generate an ordered restriction map of genomic DNA extracted from whole cells, nuclei, whole chromosomes, or other sources of long DNA molecules. The devices have a fluidic microchannel that merges into a reaction nanochannel that merges into a detection nanochannel at an interface where the nanochannel diameter decreases in size by between 50% to 99%. Intact molecules of DNA are transported to the reaction nanochannel and then fragmented in the reaction nanochannel using restriction endonuclease enzymes. The reaction nanochannel is sized and configured so that the fragments stay in an original order until they are injected into the detection nanochannel. Signal at one or more locations along the detection nanochannel is detected to map fragments in the order they occur along a long DNA molecule. |
| FILED | Tuesday, April 10, 2018 |
| APPL NO | 15/949178 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 2300/0896 (20130101) B01L 2400/0418 (20130101) B01L 2400/0421 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/683 (20130101) C12Q 1/683 (20130101) C12Q 1/6869 (20130101) C12Q 2561/113 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44791 (20130101) Original (OR) Class G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571463 | Cooper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI INTERNATIONAL (Menlo Park, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | David E. Cooper (Menlo Park, California); Robert Balog (Menlo Park, California); Polly Chang (Menlo Park, California); Thomas A. Shaler (Menlo Park, California); Hua Lin (Menlo Park, California); Annalisa D'Andrea (Menlo Park, California); Travis Harrison (Menlo Park, California); Roger H. Schmidt (Menlo Park, California); Christina Swanson (Menlo Park, California); Estevan Mendoza (Menlo Park, California); Mark Steele (Menlo Park, California); Pablo E. Garcia (Menlo Park, California) |
| ABSTRACT | Materials, systems and methods are provided for qualitative assessment of exposure of a person to ionizing radiation by measuring amounts of the biomarkers, wherein a change compared with corresponding un-irradiated control reference ranges of the biomarkers, provides the assessment, wherein the biomarkers include (i) alpha-1-Antichymotrypsin (ACT), (ii) Fms-related tyrosine kinase 3 ligand (Flt3L), and (iii) one or more additional proteins. |
| FILED | Monday, July 23, 2018 |
| APPL NO | 16/042108 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/491 (20130101) G01N 33/558 (20130101) G01N 33/5302 (20130101) Original (OR) Class G01N 33/6893 (20130101) G01N 2800/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571473 | Mitra |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (Saint Louis, Missouri) |
| ASSIGNEE(S) | Washington University (Saint Louis, Missouri) |
| INVENTOR(S) | Robi D. Mitra (Fenton, Missouri) |
| ABSTRACT | Methods are disclosed for identifying one or more proteins or polypeptides comprised by a sample. The methods comprise determining binding of each polypeptide with respect to each binding pool of a plurality of binding pools, wherein each binding pool comprises one or more probes which bind a structure comprised by a protein or polypeptide. In some aspects, polypeptides can be denatured and separated into individual polypeptide strands and immobilized on a solid support prior to determining binding of the binding pools. A protein, polypeptide or polypeptide strand can be identified by searching, in at least one database, for a protein or polypeptide sequence comprising binding pool targets either identical to or most similar to the binding pool targets comprised by the protein, polypeptide or polypeptide strand to be identified. Kits for identifying proteins, polypeptides and polypeptide strands are also disclosed. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/235038 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/6845 (20130101) Original (OR) Class G01N 33/54306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571478 | Paczesny |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Sophie Paczesny (Indianapolis, Indiana) |
| ABSTRACT | A four-biomarker panel for diagnosis of chronic graft-versus-host disease (cGVHD) and methods of prognosing and/or diagnosing cGVHD using the biomarker panel are disclosed. |
| FILED | Monday, November 23, 2015 |
| APPL NO | 15/529595 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/18 (20130101) C07K 16/24 (20130101) C07K 16/244 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/6863 (20130101) G01N 33/6869 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2333/95 (20130101) G01N 2333/522 (20130101) G01N 2333/7155 (20130101) G01N 2333/96486 (20130101) G01N 2800/52 (20130101) G01N 2800/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571539 | Hammer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Reuven Hammer (Evanston, Illinois); James R. Booth (Evanston, Illinois); Reza Borhani (Evanston, Illinois); Aggelos K. Katsaggelos (Evanston, Illinois) |
| ABSTRACT | Using a plurality of distinct behavioral tasks conducted in a functional magnetic resonance imaging (fMRI) scanner, fMRI data acquired from one or more subjects performing working memory tasks can be used for diagnosing psychiatrics and neurological disorders. A classification algorithm can be used to determine a classification model, tune the model, and apply the model. An output indicative of a subject's clinical condition can then be provided and used to diagnose new cases. |
| FILED | Friday, June 12, 2015 |
| APPL NO | 15/317724 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/168 (20130101) A61B 5/7235 (20130101) A61B 5/7282 (20130101) A61B 2576/026 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4604 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 2207/10088 (20130101) G06T 2207/30016 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573191 | Michalowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Adventium Enterprises, LLC (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Andamio Games LLC (Minneapolis, Minnesota) |
| INVENTOR(S) | Martin Michalowski (Minneapolis, Minnesota); Todd P. Carpenter (St. Paul, Minnesota); Kyle S. Nelson (Minneapolis, Minnesota) |
| ABSTRACT | Systems, devices, and methods associated with interactive educational tools are described herein. One device includes instructions executable by a processor to cause a plurality of mobile devices to each represent a respective subsystem associated with an objective, cause an interaction between at least two of the plurality of mobile devices to represent a relationship between the respective subsystems represented by the at least two mobile devices, and aggregate a number of interactions between the at least two of the plurality of mobile devices to form a coordinated response associated with achieving a particular objective. |
| FILED | Monday, June 18, 2018 |
| APPL NO | 16/011575 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/125 (20130101) G09B 7/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574298 | Pierson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Timothy J. Pierson (Hanover, New Hampshire); Xiaohui Liang (West Lebanon, New Hampshire); Ronald Peterson (Brattleboro, Vermont); David Kotz (Lyme, New Hampshire) |
| ABSTRACT | Apparatus and method securely transfer first data from a source device to a target device. A wireless signal having (a) a higher speed channel conveying second data and (b) a lower speed channel conveying the first data is transmitted. The lower speed channel is formed by selectively transmitting the wireless signal from one of a first and second antennae of the source device based upon the first data. The first and second antenna are positioned a fixed distance apart and the target device uses a received signal strength indication (RSSI) of the first signal to decode the lower speed channel and receive the first data. |
| FILED | Thursday, June 23, 2016 |
| APPL NO | 15/739122 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 5/0031 (20130101) Original (OR) Class H04B 17/318 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574313 | Shepard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Skylark Wireless, LLC (Houston, Texas) |
| ASSIGNEE(S) | Skylark WL Holdings, LLC (Houston, Texas) |
| INVENTOR(S) | Clayton Wells Shepard (Houston, Texas); Evan J. Everett (Houston, Texas); Ashutosh Sabharwal (Houston, Texas); Lin Zhong (Houston, Texas) |
| ABSTRACT | Technique for full-duplex transmission in many-antenna multi-user (MU) multiple-input multiple-output (MIMO) systems is presented in this disclosure. An estimate of a self-interference channel between a plurality of transmit antennas and a plurality of receive antennas is first obtained. A precoder for self-interference reduction is generated based on minimizing a self-interference power related to the self-interference channel that is present at the plurality of receive antennas. Transmission data are modified using the precoder by projecting the transmission data onto a defined number of singular vectors of the self-interference channel that correspond to the defined number of smallest singular values of the self-interference channel. Data are received in full-duplex mode via the plurality of receive antennas simultaneously with transmitting the modified transmission data. |
| FILED | Saturday, April 23, 2016 |
| APPL NO | 15/540129 |
| ART UNIT | 2477 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 7/0452 (20130101) H04B 7/0456 (20130101) Original (OR) Class H04B 7/0615 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10575277 | Luo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Zhihong Luo (Cambridge, Massachusetts); Qiping Zhang (Hong Kong, China Hong Kong); Nicholas Selby (Cambridge, Massachusetts); Yunfei Ma (Santa Clara, California); Manish Singh (Delhi, India); Fadel Adib (Cambridge, Massachusetts) |
| ABSTRACT | A wideband, radio-frequency localization system may estimate the one-dimensional, two-dimensional or three-dimensional position and trajectory of a static or moving object. These estimates may have a high spatial accuracy and low latency. The localization may be determined based on phase or amplitude of a wideband signal in each frequency band in a set of multiple frequency bands. The localization may be based on a single shot of measurements across a wide band of radio frequencies, without frequency hopping. The measurements of the wideband signal may be taken over time and over space at multiple receivers. The localization may be based on measurements taken while a backscatter node remains in a first reflective state or in a second reflective state, rather than when the backscatter node is transitioning between reflective states. In some cases, the localization achieves sub-centimeter spatial resolution in each of three spatial dimensions. |
| FILED | Tuesday, October 16, 2018 |
| APPL NO | 16/162085 |
| ART UNIT | 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0221 (20130101) G01S 5/0278 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0007 (20130101) H04L 27/265 (20130101) Wireless Communication Networks H04W 64/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10568840 | Karp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Jeffrey Karp (Brookline, Massachusetts); Nitin Joshi (Quincy, Massachusetts); Xueyin He (Ontario, Canada); Sachin Bhagchandani (Cambridge, Massachusetts) |
| ABSTRACT | A self-assembled gel composition with enhanced adhesion to cartilage tissue is provided. A cationic agent co-self assembles with a generally regarded as safe (GRAS), low molecular weight (<2,500 Da) gelator, forming homogeneous self-supporting gel that can encapsulate one or more therapeutic agents for controlled release. The composition adheres to connective tissue, e.g., cartilage, to a greater extent and a greater length of time than a self-assembled gel from gelators alone. The composition is used to specifically target connective tissue and deliver one or more therapeutic, prophylactic, or diagnostic agents for controlled release to improve dosing efficacy. |
| FILED | Monday, May 08, 2017 |
| APPL NO | 15/589891 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 9/70 (20130101) A61K 9/4833 (20130101) Original (OR) Class A61K 9/5015 (20130101) A61K 31/10 (20130101) A61K 31/40 (20130101) A61K 31/55 (20130101) A61K 31/167 (20130101) A61K 31/245 (20130101) A61K 31/437 (20130101) A61K 31/495 (20130101) A61K 31/7024 (20130101) A61K 31/7028 (20130101) A61K 47/14 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568844 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yunfeng Lu (Culver City, California); Irvin S. Y. Chen (Palos Veerdes Estate, California); Ming Yan (Encino, California); Min Liang (Encino, California); Masakazu Kamata (Los Angeles, California); Jing Wen (Culver City, California) |
| ABSTRACT | Novel siRNA and shRNA nanocapsules and delivery methods are disclosed herein. These siRNA and shRNA nanocapsules and delivery methods are highly robust and effective. This invention provides a platform for RNAi delivery with low toxicity and long intracellular half-life for practical therapeutic applications. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 15/721501 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) Original (OR) Class A61K 9/5138 (20130101) A61K 9/5192 (20130101) A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 47/14 (20130101) A61K 47/18 (20130101) A61K 47/20 (20130101) A61K 47/22 (20130101) A61K 47/42 (20130101) A61K 47/6925 (20170801) A61K 47/6933 (20170801) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/111 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569062 | Franklin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Prytime Medical Devices, Inc. (Boerne, Texas) |
| ASSIGNEE(S) | Prytime Medical Devices, Inc. (Boerne, Texas) |
| INVENTOR(S) | Curtis J. Franklin (Lakewood, Colorado) |
| ABSTRACT | A low profile occlusion catheter having a guiding atraumatic tip that prevents entry of the balloon into collateral vessels. The occlusion catheter system is particularly well suited for use in vascular occlusion and includes a pressure monitoring line to monitor the degree and state of occlusion. |
| FILED | Tuesday, September 09, 2014 |
| APPL NO | 14/917286 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/02 (20130101) A61L 29/04 (20130101) A61L 29/06 (20130101) A61L 29/06 (20130101) A61L 29/18 (20130101) A61L 2400/16 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/008 (20130101) A61M 25/0068 (20130101) A61M 25/1006 (20130101) Original (OR) Class A61M 2025/0002 (20130101) A61M 2025/1079 (20130101) Compositions of Macromolecular Compounds C08L 77/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569423 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Anthony D. Jones (San Diego, California); Gregory W. Anderson (San Diego, California); Wayne P. Liu (Honolulu, Hawaii); Maxwell M. Kerber (San Diego, California); Michael R. Murphy (San Diego, California) |
| ABSTRACT | A target spar. A left jaw member. The left guidance portion has a left spiral curve. The left arm portion has a left arm profile, a left arm gear, and a left arm protrusion. A right jaw member. The right guidance portion has a right spiral curve. The right arm portion comprises a right arm gear and a right arm protrusion. A top plate member. A bottom plate member. A drive unit comprising an electric motor within a pressure housing. A drive shaft on the electric motor. The bottom plate member abuts the left jaw member, the right jaw member, and the top plate member. The left jaw member and the right jaw member opened and closed. At the closed position, the target spar is slidably received in the left and right jaw members, the top and bottom plate members, and abuts the left and right arm profiles. |
| FILED | Wednesday, November 28, 2018 |
| APPL NO | 16/202383 |
| ART UNIT | 3617 — Material and Article Handling |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0009 (20130101) B25J 15/0033 (20130101) Original (OR) Class Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 2008/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569839 | Thomson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Bret R. Thomson (San Diego, California); Brandon J. Wiedemeier (San Diego, California) |
| ABSTRACT | A buoy, comprising a body, an inflatable bladder, a bladder cover, a pressure vessel, a variable-volume, gas-filled chamber, a controller, a compressor, and a ballast. The bladder cover surrounds the inflatable bladder. When the inflatable bladder is deflated, the bladder cover is configured to compress the inflatable bladder so as to conform to an exterior contour of the body. The variable-volume, gas-filled chamber provides passive, variable buoyancy to the buoy. The controller is configured to control a transfer of compressible gas between the inflatable bladder and the first pressure vessel. The compressor is configured to remove gas from the inflatable bladder, compress the removed gas, and introduce the compressed gas to the first pressure vessel for storage. The ballast maintains a substantially vertical orientation of the buoy when the buoy is in water. |
| FILED | Thursday, September 27, 2018 |
| APPL NO | 16/143664 |
| ART UNIT | 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 22/18 (20130101) Original (OR) Class B63B 2207/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569865 | Birchette et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Terrence S. Birchette (Chandler, Arizona); Akif O. Bolukbasi (Mesa, Arizona) |
| ABSTRACT | An active landing gear damping system and method for decelerating a vehicle during a terrain impact event, such as an aircraft landing or crash. The system monitors aircraft state data and terrain information to predict an impact of the vehicle with the terrain. The system can then determine a target damper force for each landing gear of the vehicle and a predicted damper velocity at the time of impact. Each landing gear can include an adjustable damper valve, wherein adjustment of the damper valves varies the damping coefficient of the respective dampers. The system can adjust valves of the respective dampers to provide the target force based on the predicted damper velocity. After an impact begins, the system can continuously monitor and adjust the valve to maintain the target force. |
| FILED | Friday, August 17, 2018 |
| APPL NO | 16/104680 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 25/58 (20130101) B64C 25/60 (20130101) Original (OR) Class Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 45/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570011 | Swanson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul D. Swanson (Santee, California); Andrew Wang (San Diego, California) |
| ABSTRACT | A method for fabricating a microelectromechanical system device. Submerging a microelectromechanical system device in water. The microelectromechanical system devices include a sacrificial layer deposited on the surface of a substrate between the portion of a structural layer to be freed for movement and a base. Anodically etching the sacrificial layer from the microelectromechanical device to free the portion of the structural layer for movement. A system comprising a solution of water, a microelectromechanical system device including a sacrificial layer of chromium deposited on the surface of a substrate between a portion of a structural layer and a base. The microelectromechanical system device is submerged in the solution of water. An electrode is submerged in the water. The electrode provides a negative bias. A voltage source provides a positive bias to the sacrificial layer of chromium, anodically etching the sacrificial layer of chromium and freeing the portion of the structural layer. |
| FILED | Thursday, August 30, 2018 |
| APPL NO | 16/117456 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00476 (20130101) Original (OR) Class B81C 99/0025 (20130101) B81C 2201/0107 (20130101) B81C 2201/0139 (20130101) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570284 | Ferrari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | APG Polytech, LLC (Wilmington, Delaware) |
| ASSIGNEE(S) | APG Polytech, LLC (Wilmington, Delaware) |
| INVENTOR(S) | Gianluca Ferrari (Portograuaro, Italy); D. Jeffrey Black (Akron, Ohio) |
| ABSTRACT | Disclosed herein is an oxygen scavenging composition for containers. The oxygen scavenging composition may comprise at least one polyester component, which is a copolyester containing a metal sulfonate salt group, a transition metal catalyst, and a vegetable oil. The vegetable oil may comprise at least one molecule having a double allylic structure. The copolyester containing a metal sulfonate salt group may comprise at least one acid unit and at least one diol unit. The concentration of the double allylic structures of the vegetable oil in the composition may be greater than 5.0 meq/kg of all of the polyester components. The composition may also be void of or substantially void of a polyamide. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/735642 |
| ART UNIT | 1768 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 49/0005 (20130101) B29C 49/06 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/003 (20130101) B29K 2105/0014 (20130101) B29K 2995/0053 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7158 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 5/20 (20130101) C08K 5/098 (20130101) C08K 5/3445 (20130101) C08K 11/00 (20130101) C08K 2003/2241 (20130101) C08K 2201/012 (20130101) Compositions of Macromolecular Compounds C08L 67/02 (20130101) C08L 67/02 (20130101) C08L 67/03 (20130101) C08L 91/00 (20130101) Original (OR) Class C08L 91/00 (20130101) C08L 2201/08 (20130101) C08L 2203/10 (20130101) C08L 2203/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570541 | Kladitis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Dayton (Dayton, Ohio); Nanocomp Technologies Inc. (The Woodlands, Texas) |
| ASSIGNEE(S) | University of Dayton (Dayton, Ohio); Nanocomp Technologies, Inc. (The Woodlands, Texas) |
| INVENTOR(S) | Paul Kladitis (Clayton, Ohio); Lingchuan Li (Dayton, Ohio); Brian Rice (Mason, Ohio); Zongwu Bai (Beavercreek, Ohio); David Gailus (Merrimack, New Hampshire) |
| ABSTRACT | Carbon nanotube threads are coated with a coating solution such as dimethylformamide (DMF), ethylene glycol (EG), polyethylene glycol (PEG), PEG200 (PEG with an average molecular weight of approximately 200 grams per mole (g/mol)), PEG400 (PEG with an average molecular weight of approximately 400 g/mol), aminopropyl terminated polydimethylsiloxane (DMS 100 cP),polymide, poly(methylhydrosiloxane), polyalkylene glycol, (3-aminopropyl)trimethoxysilane, hydride functional siloxane O resin, platinum (0) -1,3-divinyl-1,1,3,3-tetramethyl-disiloxane, moisture in air, acetic acid, water, poly(dimethylsiloxane) hydroxy terminated, (3-glycidyloxypropyl)-trimethoxysilane or a combination thereof. The coated carbon nanotubes may be used to stitch in a Z-direction into a composite such as a polymer prepreg to strengthen the composite. The stitching may occur using a sewing machine. |
| FILED | Wednesday, June 28, 2017 |
| APPL NO | 15/636075 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Apparatus for Applying Fluent Materials to Surfaces, in General B05C 3/125 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/168 (20170801) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) Sewing D05B 43/00 (20130101) D05B 93/00 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/745 (20130101) Y10S 977/847 (20130101) Y10S 977/961 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570751 | Kreitzer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Paul Joseph Kreitzer (West Chester, Ohio); Bradford Alan Tracey (Cold Spring, Kentucky); Michael Everitt Isenberg (Cincinatti, Ohio); Thomas Joseph Lipinski (Monroe, Ohio); Scott Alan Schimmels (Miamisburg, Ohio); Kenneth Jay Moore (Hamilton, Ohio) |
| ABSTRACT | An airfoil assembly for a turbine engine can include an airfoil having an outer wall bounding an interior, and an insert located within the interior with a space between the insert and airfoil outer wall. A cooling hole can pass through the insert with an outlet fluidly coupled to the space between the insert and outer wall. |
| FILED | Wednesday, November 22, 2017 |
| APPL NO | 15/820613 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/189 (20130101) Original (OR) Class F01D 9/02 (20130101) F01D 25/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Jet-propulsion Plants F02K 3/06 (20130101) Non-positive-displacement Pumps F04D 29/324 (20130101) F04D 29/542 (20130101) F04D 29/582 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/80 (20130101) F05D 2260/201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570762 | Dibenedetto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Enzo Dibenedetto (Kensington, Connecticut); Matthew E. Bintz (West Hartford, Connecticut) |
| ABSTRACT | A vane strut positioning and securement system includes a housing including a washer aperture defined in an inner diameter thereof and a lock washer disposed within the washer aperture of the housing, the lock washer configured to lock a vane strut orientation under compression against a vane strut washer. The washer aperture is defined partially through a thickness of the housing, and the housing includes a strut post opening defined through the housing from the inner diameter to an outer diameter of the housing. |
| FILED | Friday, May 15, 2015 |
| APPL NO | 14/713002 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/042 (20130101) Original (OR) Class F01D 17/162 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/28 (20130101) F05D 2250/29 (20130101) F05D 2300/211 (20130101) F05D 2300/2112 (20130101) F05D 2300/2282 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 2/005 (20130101) F16B 5/02 (20130101) F16B 39/24 (20130101) F16B 39/225 (20130101) F16B 39/282 (20130101) F16B 43/00 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570763 | Himes |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Jason D. Himes (Tolland, Connecticut) |
| ABSTRACT | A seal assembly for a gas turbine engine includes a primary seal that includes an inner face that has a protrusion configured to seal relative to a seal land. The protrusion provided on segmented shoes is circumferentially spaced from one another by gaps. The shoes are positioned in a relaxed state. A removable material encases the protrusion with the shoes in the relaxed state. |
| FILED | Monday, June 22, 2015 |
| APPL NO | 14/745593 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/001 (20130101) F01D 11/003 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2300/43 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570770 | Ward |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Eric J. Ward (West Palm Beach, Florida) |
| ABSTRACT | A variable vane assembly for a gas turbine engine includes at least one synchronization ring, a plurality of variable vanes connected to the synchronization ring, a plurality of torque boxes disposed circumferentially about the synchronization ring, a drive ring coupled to each of the torque boxes such that the drive ring causes an approximately identical torque to be applied to the synchronization ring from the torque boxes simultaneously, and an actuator coupled to one of the plurality of torque boxes and operable to drive the drive ring through the torque box. |
| FILED | Monday, December 08, 2014 |
| APPL NO | 15/103676 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/162 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Non-positive-displacement Pumps F04D 29/563 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/57 (20130101) F05D 2270/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570876 | Ruffa |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Anthony A Ruffa (Hope Valley, Rhode Island) |
| ABSTRACT | An energy harvesting pendulum device is provided to oscillate in a semi-circular path on an inclined plane with a low friction surface in response to wave motion of an ocean surface. An electrical production source is mounted to an underside of the plane to convert kinetic energy of a pendulum bob of the pendulum device into electrical energy. The pendulum device can be enclosed by an enclosure floating on the ocean surface with the pendulum moving bob on the inclined plane within the enclosure. The length of the pendulum and the angle of the inclined plane are determined so that the pendulum operates in a resonant state at the ocean motion frequency. The pendulum bob can include rollers for minimal friction when contacting the inclined plane. |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/026138 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Machines or Engines for Liquids F03B 13/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570926 | Maciolek |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Robert F. Maciolek (Glen Mills, Pennsylvania) |
| ABSTRACT | A variable-geometry ducted fan may include an air duct having a longitudinal axis, the air duct including an inlet of the variable-geometry ducted fan, a fan rotatably mounted within the air duct downstream from the inlet, the fan including fan blades defining a fan area, and a variable-area nozzle coupled to the air duct downstream from the fan, the variable-area nozzle including an exhaust of the variable-geometry ducted fan having a variable exhaust area. |
| FILED | Thursday, December 03, 2015 |
| APPL NO | 14/958154 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 7/02 (20130101) B64C 11/001 (20130101) B64C 29/0033 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/04 (20130101) B64D 35/04 (20130101) Jet-propulsion Plants F02K 1/12 (20130101) Non-positive-displacement Pumps F04D 19/002 (20130101) F04D 29/547 (20130101) F04D 29/563 (20130101) Original (OR) Class Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2220/90 (20130101) F05B 2240/123 (20130101) F05B 2250/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570944 | Ruberte Sanchez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Jose E. Ruberte Sanchez (Jupiter, Florida); Joey Wong (Enfield, Connecticut); Mark J. Ricciardo (Royal Palm Beach, Florida); Russell B. Hanson (Jupiter, Florida) |
| ABSTRACT | A gas turbine engine includes a bushing that is non-round in cross-section, the bushing receivable within an aperture. A fastener passes through the bushing to retain a second component to a third component with respect to the first component. |
| FILED | Wednesday, September 14, 2016 |
| APPL NO | 15/265205 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/20 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/30 (20130101) F05D 2260/31 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 33/002 (20130101) Original (OR) Class F16B 35/048 (20130101) F16B 39/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570950 | Simpson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Framington, Connecticut) |
| INVENTOR(S) | Alex J. Simpson (Tolland, Connecticut); Edward A. Krystowski (Granby, Connecticut) |
| ABSTRACT | A bearing joint assembly includes a bearing sleeve, a first mount, a pair of second mounts and a fastener. The bearing sleeve extends axially along a centerline and includes a spherical bearing, a first collar and a second collar. The spherical bearing is axially between the first collar and the second collar. An annular channel is formed by and extends axially between the spherical bearing and the first collar. The first mount is mounted on and slidably engages the spherical bearing. The bearing sleeve is axially between the second mounts. The fastener projects through the bearing sleeve and secures the bearing sleeve to the second mounts. |
| FILED | Monday, May 23, 2016 |
| APPL NO | 15/161895 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 11/0604 (20130101) Original (OR) Class F16C 11/0695 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571074 | Matalanis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY ARICRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Claude G. Matalanis (Longmeadow, Massachusetts); Ulf J. Jonsson (South Windsor, Connecticut); John D. Cannata (Marlborough, Connecticut); Brian E. Wake (South Glastonbury, Connecticut) |
| ABSTRACT | According to one aspect, a lubricant level sensing system for an actuator is provided. The lubricant level sensing system includes a pressure port in an outer housing of the actuator, a pressure sensor, and a pathway from the pressure port to the pressure sensor. The pathway establishes fluid communication between the pressure sensor and a free volume of an internal cavity of the outer housing relative to a lubricant level in the internal cavity such that the pressure sensor detects a pressure of the free volume used to derive the lubricant level. |
| FILED | Thursday, August 27, 2015 |
| APPL NO | 15/520016 |
| ART UNIT | 3654 — Material and Article Handling |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/72 (20130101) B64C 27/615 (20130101) B64C 2027/7294 (20130101) Lubricating F16N 29/00 (20130101) Original (OR) Class F16N 2250/04 (20130101) F16N 2250/18 (20130101) Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571200 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kelvin Thermal Technologies, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | KELVIN THERMAL TECHNOLOGIES, INC. (Boulder, Colorado) |
| INVENTOR(S) | Ronggui Yang (Broomfield, New York); Yung-Cheng Lee (Boulder, Colorado); Victor M. Bright (Boulder, Colorado); Chen Li (Columbia, South Carolina); Christopher Oshman (Boulder, Colorado); Bo Shi (Nanjing, China PRC); Jen-Hau Cheng (Boulder, Colorado); George P. Peterson (Atlanta, Georgia) |
| ABSTRACT | Methods, apparatuses, and systems are disclosed for flexible thermal ground planes. A flexible thermal ground plane may include a support member. The flexible thermal ground plane may include an evaporator region or multiple evaporator regions configured to couple with the support member. The flexible thermal ground plane may include a condenser region or multiple condenser regions configured to couple with the support member. The evaporator and condenser region may include a microwicking structure. The evaporator and condenser region may include a nanowicking structure coupled with the micro-wicking structure, where the nanowicking structure includes nanorods. The evaporator and condenser region may include a nanomesh coupled with the nanorods and/or the microwicking structure. Some embodiments may include a micromesh coupled with the nanorods and/or the microwicking structure. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/436632 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/26 (20130101) B23P 2700/09 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/04 (20130101) F28D 15/046 (20130101) F28D 15/0233 (20130101) F28D 15/0241 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/427 (20130101) H01L 23/473 (20130101) H01L 23/3677 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49353 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571212 | Rivera Marchand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David Rivera Marchand (Alexandria, Virginia); Angel Diaz (Indian Head, Maryland); Daniel McCarthy (LaPlata, Maryland); Michael G. Craft (Waldorf, Maryland); Walter Hubbard (LaPlata, Maryland); Nicholas Shaker (Springfield, Virginia) |
| ABSTRACT | A process that uses a lodged projectile removal charge (LPRC) apparatus to remove a projectile jammed in a cannon's gun tube. The LPRC is positioned coaxially and offset from the projectile, and the gun tube is filled with water. The charge is detonated producing a shock wave that disintegrates the LPRC apparatus and pressurizes the water. The pressurized water produces a radial hydraulic force against an interior wall of the gun tube, an axial hydraulic force against the projectile pushing the projectile toward the chamber, and produces an opposing expansion of explosive gases that blasts out most of the water in the gun tube. The process is less likely to damage the gun tube. The LPRC may be made using a 3D printer. |
| FILED | Tuesday, September 25, 2018 |
| APPL NO | 16/350088 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cleaning in General; Prevention of Fouling in General B08B 7/0007 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 29/00 (20130101) Original (OR) Class Apparatus for Launching Projectiles or Missiles From Barrels, e.g Cannons; Launchers for Rockets or Torpedoes; Harpoon Guns F41F 3/058 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 1/02 (20130101) Blasting F42D 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571227 | Rastegar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jahangir S Rastegar (Stony Brook, New York); Richard T Murray (Patchogue, New York); Gretel Raibeck (Rockaway, New Jersey); Jay Poret (Sparta, New Jersey); Brandon Andreola (Lake Hiawatha, New Jersey); Andrew Zimmer (Wharton, New Jersey) |
| ASSIGNEE(S) | OMNITEK PARTNERS LLC (Ronkonkoma, New York) |
| INVENTOR(S) | Jahangir S Rastegar (Stony Brook, New York); Richard T Murray (Patchogue, New York); Gretel Raibeck (Rockaway, New Jersey); Jay Poret (Sparta, New Jersey); Brandon Andreola (Lake Hiawatha, New Jersey); Andrew Zimmer (Wharton, New Jersey) |
| ABSTRACT | A flare including: a casing; and a grain assembly, at least a portion of the grain assembly being slidably disposed in the casing, the grain assembly including: a shell structure; and a grain component at least partially disposed in the shell structure, the grain component including at least one combustible material and at least one reactive material positioned relative to the combustible material and configured to ignite combustion of the at least one combustible material; wherein the shell structure includes one or more fins at an aft end of the shell structure, the one or more fins being restrained into a first shape in the casing and configured to have a second shape, different from the first shape, when the restraint is removed. |
| FILED | Monday, July 10, 2017 |
| APPL NO | 15/646059 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Targets; Target Ranges; Bullet Catchers F41J 2/00 (20130101) F41J 2/02 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 4/26 (20130101) Original (OR) Class F42B 10/14 (20130101) F42B 10/16 (20130101) F42B 10/26 (20130101) F42B 15/00 (20130101) F42B 15/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571232 | Hoffman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | US. Government as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Brian R. Hoffman (Bangor, Pennsylvania) |
| ABSTRACT | A cartridge case with a case crush region that facilitates an additional amount of case crush in the axial direction, per unit of input force and energy, as compared to an identical cartridge case without such a region. The crush region may conceivably be either of a fully or partially circumferential nature with applicability to any style cartridge case, be it bottleneck or straight-walled and of any rim configuration (rimmed, semi-rimmed, rimless, rebated-rim, belted) and without prejudice to the case material (brass, stainless steel, polymer, etc.). This feature may be incorporated into the design of existing cartridge cases as well as future designs. |
| FILED | Tuesday, September 11, 2018 |
| APPL NO | 16/127474 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/34 (20130101) Original (OR) Class F42B 30/02 (20130101) F42B 33/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571234 | Morelli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | William Morelli (Spring Lake, New Jersey); Stojan Kotefski (Bloomingdale, New Jersey); Nikola Kotevski (Bloomingdale, New Jersey); Ductri Nguyen (Parsippany, New Jersey); Dominick DeMella (Hamburg, New Jersey); Paul Manz (Andover, New Jersey); Philip Magnotti (Westfield, New Jersey) |
| ABSTRACT | A venting lifting plug is provided for an unfuzed munition having a cavity with internal threads. |
| FILED | Wednesday, March 14, 2018 |
| APPL NO | 15/920636 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 39/14 (20130101) F42B 39/20 (20130101) Original (OR) Class Ammunition Fuzes; Arming or Safety Means Therefor F42C 19/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571311 | Skrabacz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Eric R. Skrabacz (Aberdeen, Maryland); Paul R. Schuster (Baltimore, Maryland) |
| ABSTRACT | A method of detecting tampering with a conveyance medium may include determining a baseline brightness level detected at opposing ends of an optical fiber segment disposed proximate to the conveyance medium, determining whether a change in brightness above a threshold level occurs, and providing an output indicating that a breach in continuity of a shielding material that shields both the conveyance medium and the optical fiber segment from exposure to ambient light has occurred in response to the change in brightness being above the threshold level. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 15/899708 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/35345 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/447 (20130101) G02B 6/504 (20130101) G02B 6/4206 (20130101) G02B 6/4298 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571483 | Bramhavar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Suraj Deepak Bramhavar (Cambridge, Massachusetts); Paul William Juodawlkis (Arlington, Massachusetts) |
| ABSTRACT | An accelerometer may comprise a proof mass, a first tether mechanically coupled to the side of the proof mass and to an anchor, and a ring resonator integrated with the tether to form a sensing tether. The ring resonator and the tether may be configured such that a strain sustained by the sensing tether causes a change of a resonance condition of the ring resonator. The accelerometer may comprise a wavelength locking loop configured to adaptively maintain a center frequency of the light energy at a resonant frequency of the sensing element, and a scale factor calibrator configured to stabilize a scale factor associated with the accelerometer. The accelerometer may further include a detection processor configured to receive the detection signal and produce an acceleration signal therefrom. The acceleration signal may correspond to an amount of change of the resonance condition with respect to a reference resonance condition. |
| FILED | Wednesday, November 08, 2017 |
| APPL NO | 15/807531 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/032 (20130101) G01P 15/093 (20130101) Original (OR) Class G01P 15/097 (20130101) G01P 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571505 | Keller, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NOKOMIS, INC. (Charleroi, Pennsylvania) |
| ASSIGNEE(S) | NOKOMIS, INC. (Charleroi, Pennsylvania) |
| INVENTOR(S) | Walter John Keller, III (Bridgeville, Pennsylvania); Andrew Richard Portune (Oakdale, Pennsylvania); Todd Eric Chornenky (Carmichaels, Pennsylvania); William Anthony Davis (Perrysburg, Ohio) |
| ABSTRACT | An apparatus for detecting a condition or authenticity of one or more electronic devices includes an enclosure having an antenna integrated therewithin, a fixture mounted within a hollow interior of the enclosure, the fixture being configured to receive the one or more electronic devices and connect one or more signals to each of the one or more electronic devices and a sensor and controller assembly connected to the antenna and configured to process a signature of an emission of a radiofrequency (RF) energy from of one or more electronic devices having the one or more signals connected thereto. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/847819 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/002 (20130101) Original (OR) Class Electric Digital Data Processing G06F 21/73 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571520 | Maliuk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | Internatioanl Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dzmitry S. Maliuk (Addison, Texas); Franco Stellari (Waldwick, New Jersey); Alan J. Weger (Mohegan Lake, New York); Peilin Song (Lagrangeville, New York) |
| ABSTRACT | A scan chain latch circuit, a method of operating a latch circuit in a scan chain, and a computer-readable medium having stored thereon a data structure defining a scan chain latch circuit for instantiation on a semiconductor die are disclosed. In an embodiment, the scan chain latch circuit comprises a first latch for holding one data value, a second latch for holding another data value, and a multiplexor. The one data value is applied to a first data input of the multiplexor and the another data value is applied to a second data input of the multiplexor. An alternating clock signal is applied to a select input of the multiplexor to control the output of the multiplexor, wherein the output of the multiplexor toggles between the two data values held in the two latches at a defined frequency. |
| FILED | Tuesday, May 09, 2017 |
| APPL NO | 15/590617 |
| ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3177 (20130101) Original (OR) Class G01R 31/31723 (20130101) G01R 31/31727 (20130101) G01R 31/318516 (20130101) G01R 31/318519 (20130101) G01R 31/318541 (20130101) G01R 31/318572 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571556 | Fleizach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gregory Knowles Fleizach (San Diego, California); Barry Hunt (San Diego, California) |
| ABSTRACT | A device for detecting frequency modulated continuous wave radar includes an antenna connected to a bandpass filter. The antenna is configured to receive frequency modulated continuous wave (FMCW) pulses within a predetermined frequency range. A frequency mixer is connected to the bandpass filter and a synthesizer and is configured to mix a signal from the synthesizer with an output of the bandpass filter to produce basebanded data. A high-pass filter is configured to isolate short pulses pertaining to the basebanded data, and a low-pass filter is configured to isolate long pulses pertaining to the basebanded data. A microprocessor is configured to set thresholds for comparison with the outputs of the high-pass filter and the low-pass filter. |
| FILED | Monday, September 18, 2017 |
| APPL NO | 15/706955 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/021 (20130101) G01S 7/352 (20130101) G01S 13/53 (20130101) G01S 13/348 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571559 | Murakowski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Phase Sensitive Innovations, Inc. (Newark, Delaware) |
| ASSIGNEE(S) | Phase Sensitive Innovations, Inc. (Newark, Delaware) |
| INVENTOR(S) | Janusz Murakowski (Bear, Delaware) |
| ABSTRACT | A vehicle such as a helicopter may scan a scene using a transmitter mounted on a rotating part like a rotor and a receiver mounted on a body of the vehicle. Based on a Doppler shift caused by the rotation of the rotating part, patterns may be recorded and used to develop a holographic image of the scene. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/591771 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/34 (20130101) G01S 13/42 (20130101) G01S 13/89 (20130101) Original (OR) Class Holographic Processes or Apparatus G03H 5/00 (20130101) G03H 2210/30 (20130101) G03H 2210/62 (20130101) G03H 2222/36 (20130101) G03H 2227/03 (20130101) G03H 2227/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571569 | Montoya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Juan C. Montoya (Belmont, Massachusetts); Antonio Sanchez-Rubio (Lexington, Massachusetts); Harold C. Payson (Lexington, Massachusetts); Robert E. Hatch (Boxborough, Massachusetts); Richard Heinrichs (Arlington, Virginia); Dale G. Fried (Dover, Massachusetts) |
| ABSTRACT | A method of imaging a scene includes generating a temporally varying optical intensity pattern from at least one continuous wave (CW) light beam. The method also includes illuminating at least one portion of the scene with the temporally varying optical intensity pattern so as to cause a photon to scatter or reflect off the at least one portion of the scene. The photon reflected or scatted from the at least one portion of the scene is detected using a single-photon detector. Based on the temporally varying optical intensity pattern and a time of flight of the photon detected, a distance between the single-photon detector and the at least one portion of the scene is estimated. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/103317 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) G01S 7/499 (20130101) G01S 7/4815 (20130101) G01S 7/4816 (20130101) G01S 7/4817 (20130101) G01S 7/4863 (20130101) G01S 17/10 (20130101) Original (OR) Class G01S 17/32 (20130101) G01S 17/42 (20130101) G01S 17/89 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571606 | Altug et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hatice Altug (Watertown, Massachusetts); Ahmet Ali Yanik (Brighton, Massachusetts); Shyamsunder Erramilli (Quincy, Massachusetts); Ronen Adato (Boston, Massachusetts); Serap Aksu (Allston, Massachusetts); Min Huang (Boston, Massachusetts); Alp Artar (Brighton, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Hatice Altug (Watertown, Massachusetts); Ahmet Ali Yanik (Brighton, Massachusetts); Shyamsunder Erramilli (Quincy, Massachusetts); Ronen Adato (Boston, Massachusetts); Serap Aksu (Allston, Massachusetts); Min Huang (Boston, Massachusetts); Alp Artar (Brighton, Massachusetts) |
| ABSTRACT | The present invention generally relates to nanoantenna arrays and fabrication methods of said nanoantenna arrays. In particular, one aspect relates to nanoantenna arrays including nanostructures of predefined shapes in predefined patterns, which results in collective excitement of surface plasmons. The nanoantenna arrays can be used for spectroscopy and nanospectroscopy. Another aspects of the present invention relate to a method of high-throughput fabrication of nanoantenna arrays includes fabricating a reusable nanostencil for nanostensil lithography (NSL) which provides a mask to deposit materials onto virtually any support, such as flexible and thin-film stretchable supports. The nanostencil lithography methods enable high quality, high-throughput fabrication of nanostructures on conducting, non-conducting and magnetic supports. The nanostencil can be prepared by etching nanoapertures of predefined patterns into a waffer or ceramic membrane. In some embodiments, a nanoantenna array includes plasmonic nanostructures or non-plasmonic nanostructures. |
| FILED | Friday, October 22, 2010 |
| APPL NO | 13/509545 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 20/00 (20130101) B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 21/658 (20130101) Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/932 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571609 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Seunghoon Han (Suwon-si, South Korea); Yu Horie (Pasadena, California); Andrei Faraon (Pasadena, California); Sungwoo Hwang (Suwon-si, South Korea) |
| ABSTRACT | An image sensor includes an optical sensor layer including a plurality of light-sensitive cells configured to sense light to generate electrical signals, and a color filter array layer disposed on the optical sensor layer and including a plurality of color filters respectively facing the plurality of light-sensitive cells. Each of the plurality of color filters includes a nanostructure in which a first material having a first refractive index and a second material having a second refractive index higher than the first refractive index are arranged. The first material and the second material are alternatively positioned at an interval less than a central wavelength of a color of the color filter. Thus, a thin image sensor having good wavelength selectivity and suitable for obtaining high resolution images is provided. |
| FILED | Wednesday, June 12, 2019 |
| APPL NO | 16/439010 |
| ART UNIT | 2696 — Selective Visual Display Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/201 (20130101) Original (OR) Class Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 33/16 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14621 (20130101) H01L 27/14625 (20130101) H01L 27/14685 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571631 | Coolbaugh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Douglas Coolbaugh (Highland, New York); Thomas Adam (Slingerlands, New York); Gerald L. Leake (Delmar, New York) |
| ABSTRACT | A photonic structure can include in one aspect one or more waveguides formed by patterning of waveguiding material adapted to propagate light energy. Such waveguiding material may include one or more of silicon (single-, poly-, or non-crystalline) and silicon nitride. |
| FILED | Monday, January 04, 2016 |
| APPL NO | 14/987710 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/13 (20130101) Original (OR) Class G02B 6/43 (20130101) G02B 6/132 (20130101) G02B 6/136 (20130101) G02B 6/1347 (20130101) G02B 6/12002 (20130101) G02B 2006/121 (20130101) G02B 2006/12104 (20130101) G02B 2006/12123 (20130101) G02B 2006/12169 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0245 (20130101) H01L 21/0262 (20130101) H01L 21/2033 (20130101) H01L 21/2053 (20130101) H01L 21/02381 (20130101) H01L 21/02505 (20130101) H01L 21/02532 (20130101) H01L 21/02573 (20130101) H01L 21/02639 (20130101) H01L 27/14625 (20130101) H01L 27/14629 (20130101) H01L 31/028 (20130101) H01L 31/105 (20130101) H01L 31/0232 (20130101) H01L 31/1808 (20130101) H01L 31/02327 (20130101) H01L 31/022408 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Y02E 10/547 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571632 | Ptasinski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joanna N. Ptasinski (San Diego, California); Stephen D. Russell (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joanna N. Ptasinski (San Diego, California); Stephen D. Russell (San Diego, California) |
| ABSTRACT | A waveguide and methods for manufacture can include a silicon wafer and a silicon substrate on the wafer that can be patterned into a silicon waveguide. A cladding can be deposited on the wafer and that waveguide using a plasma enhanced chemical vapor deposition (PECVD) process. When a PECVD process is used, the cladding portions that are in contact with that waveguide and in the immediate vicinity can have a lower density, and a lower refractive index n of less than (n<1.3). The lower uniform cladding refractive index can be uniform from the waveguide surfaces out to approximately one micrometer from the waveguide. This can further in result in an increased difference between the refractive index of the silicon waveguide and the adjacent lower refractive index cladding portions, which can further result in greater light confinement within the waveguide (i.e. reduced losses during transmission). |
| FILED | Friday, July 13, 2018 |
| APPL NO | 16/034524 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/132 (20130101) Original (OR) Class G02B 6/136 (20130101) G02B 2006/12061 (20130101) G02B 2006/12097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572207 | Kerrigan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Assured Information Security, Inc. (Rome, New York) |
| ASSIGNEE(S) | ASSURED INFORMATION SECURITY, INC. (Rome, New York) |
| INVENTOR(S) | Brendan Kerrigan (Rome, New York); Maurice Gale (Rome, New York); Rian Quinn (Highlands Ranch, Colorado); Rodney Forbes (Rome, New York); Sandy Stutsman (Westford, Massachusetts); Jonathan Farrell (Hauppauge, New York) |
| ABSTRACT | A method provides a graphical interface for a computer system and includes receiving window information from each domain of multiple domains in which applications execute. Based on the received window information, the method builds the graphical interface on a graphics device of the computer system from graphics data provided from the multiple domains to the graphics device. The graphics device includes a GPU and graphics memory having multiple graphics memory portions, where each domain is dedicated a respective different graphics memory portion and is given write access thereto. The building issues commands to the graphics device that instruct the GPU to composition together graphics data from graphics memory portion(s) to thereby composition together graphics data from each of two of more domains of the multiple domains. The method also includes issuing commands to the graphics device to output the graphical interface to a set of one or more display devices. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/019978 |
| ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 3/1431 (20130101) Original (OR) Class G06F 9/451 (20180201) G06F 9/45558 (20130101) G06F 2009/45579 (20130101) Image Data Processing or Generation, in General G06T 1/20 (20130101) G06T 1/60 (20130101) G06T 11/001 (20130101) G06T 11/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572376 | Fleming, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kermin Elliott Fleming, Jr. (Hudson, Massachusetts); Simon C. Steely, Jr. (Hudson, New Hampshire); Kent D. Glossop (Nashua, New Hampshire) |
| ABSTRACT | An integrated circuit includes a memory interface, coupled to a memory to store data corresponding to instructions, and an operations queue to buffer memory operations corresponding to the instructions. The integrated circuit may include acceleration hardware to execute a sub-program corresponding to the instructions. A set of input queues may include an address queue to receive, from the acceleration hardware, an address of the memory associated with a second memory operation of the memory operations, and a dependency queue to receive, from the acceleration hardware, a dependency token associated with the address. The dependency token indicates a dependency on data generated by a first memory operation of the memory operations. A scheduler circuit may schedule issuance of the second memory operation to the memory in response to the dependency queue receiving the dependency token and the address queue receiving the address. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/396038 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0619 (20130101) G06F 3/0659 (20130101) G06F 3/0685 (20130101) G06F 9/3838 (20130101) G06F 9/30043 (20130101) G06F 12/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572687 | Jungwirth |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Patrick W. Jungwirth (Abingdon, Maryland) |
| ABSTRACT | A microprocessor computer system for secure/high assurance/safety critical computing includes a hardware subsystem having a plurality of cache controller and cache bank modules including cache bank and memory cell hardware permission bits for managing and controlling access to system resources. A computer security framework subsystem includes a hierarchy of access layers comprising top layers and lower layers. The permission bits provide hardware level computer security primitives for a computer operating system. The top layers are completely trusted and the lower layers are moderately trusted to completely untrusted. The top layers include a trusted operating system layer that executes management and control of the system resources and permission bits. The permission bits define limits for a hardware execution security mechanism for less trusted to completely untrusted software. Exceeding bounds of the security mechanism results in a hardware exception thereby blocking all attempts to access or modify resources outside the security mechanism. |
| FILED | Thursday, March 30, 2017 |
| APPL NO | 15/474263 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0875 (20130101) G06F 12/0897 (20130101) G06F 21/78 (20130101) G06F 21/6281 (20130101) Original (OR) Class G06F 2212/1052 (20130101) G06F 2221/2141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572768 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Anthony D. Jones (San Diego, California); Wayne P. Liu (San Diego, California); Michael H. Tall (San Diego, California) |
| ABSTRACT | A method for adjusting the proportional gain value of a proportional controller for use in an unmanned underwater vehicle. The invention includes the steps of: recording at an unmanned underwater vehicle a captured image in the direction of travel; applying a first filter to the captured image; calculating a first distance from each pixel in the captured image to a specified target color; finding the selected pixel from the captured image with the minimum distance from the specified target color, normalizing the image coordinates of the selected pixel into normalized image coordinates; passing the normalized image coordinates as an error value to the proportional controller; calculating a rate of error at the proportional controller; updating the proportional gain according at the proportional controller; and applying a control signal at the proportional controller. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 15/905412 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 2008/008 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/42 (20130101) G06K 9/66 (20130101) G06K 9/4652 (20130101) G06K 9/6215 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572814 | Friesen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Mark Friesen (Middleton, Wisconsin); Mark Eriksson (Madison, Wisconsin); Susan Coppersmith (Madison, Wisconsin) |
| ABSTRACT | A quantum computing system and method for performing quantum computation is provided. In some aspects, the system includes at least one charge qubit comprising a quantum dot assembly prepared with a symmetric charge distribution, wherein the symmetric charge distribution is configured to reduce a coupling between the charge qubit and a charge noise source. The system also includes a controller for controlling the at least one charge qubit to perform a quantum computation. The system further includes an output for providing a report generated using information obtained from the quantum computation performed. |
| FILED | Friday, January 15, 2016 |
| APPL NO | 14/996918 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 15/82 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572816 | Vavilov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); University of Massachusetts (Boston, Massachusetts); University of Maryland (College Park, Maryland) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); University of Massachusetts (Boston, Massachusetts); University of Maryland, College Park (College park, Maryland) |
| INVENTOR(S) | Maxim George Vavilov (Middleton, Wisconsin); Konstantin Nesterov (Madison, Wisconsin); Vladimir Manucharyan (College Park, Maryland); Ivan Pechenezhskiy (Silver Springs, Maryland); Chen Wang (Amherst, Massachusetts) |
| ABSTRACT | A system and method for controlling qubits to perform quantum computation is provided. In some aspects, the system includes at least one superconducting quantum processor comprising a multi-qubit architecture having coupled qubits that are described by an anharmonic energy spectrum. The system also includes a microwave source connected to the at least one superconducting quantum processor, and configured to provide a microwave irradiation to at least one of the coupled qubits in the multi-qubit architecture to perform a gate on the at least one of the coupled qubits. The system further includes a controller configured to direct the microwave source to provide the microwave irradiation to at least one of the coupled qubits in the multi-qubit architecture. |
| FILED | Wednesday, December 05, 2018 |
| APPL NO | 16/210921 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Pulse Technique H03K 19/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572968 | Riabov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Anton V. Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (Port Chester, New York); Octavian Udrea (Onissing, New York) |
| ABSTRACT | Techniques for translating graphical representations of domain knowledge are provided. In one example, a computer-implemented method comprises receiving, by a device operatively coupled to a processor, a graphical representation of domain knowledge. The graphical representation comprises information indicative of a central concept and at least one chain of events associated with the central concept. The computer-implemented method further comprises translating, by the device, the graphical representation into an artificial intelligence planning problem. The artificial intelligence planning problem is expressed in an artificial intelligence description language. The translating comprises parsing the graphical representation into groupings of terms. A first grouping of terms of the grouping of terms comprises an event from the at least one chain of events and a second grouping of terms of the grouping of terms comprises the information indicative of the central concept. The computer-implemented method also comprises validating, by the device, the artificial intelligence planning problem. |
| FILED | Thursday, March 07, 2019 |
| APPL NO | 16/295731 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 16/532 (20190101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 5/022 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 1/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573056 | Burnett, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | 3D Patents, LLC (Mission Hills, Kansas) |
| ASSIGNEE(S) | 3D PATENTS, LLC (Mission Hills, Kansas) |
| INVENTOR(S) | Thomas Lawrence Burnett, III (Austin, Texas); Kendall Heath James (Austin, Texas); Ronald Craig Larcom (Cedar Park, Texas) |
| ABSTRACT | A system comprising a multi-view processing unit to provide a plurality of parallel rendering pipelines to render multiple views of a scene in parallel to render targets. The multi-view processing unit comprises a multi-view processing unit memory storing a plurality of viewpoints and a multi-view processing unit processor configured to receive a request to render a scene, load the plurality of viewpoints and implement the parallel rendering pipelines to render the scene based on the plurality of viewpoints, the plurality of parallel rendering pipeline configured to render, in parallel, image data for multiple views to a set of buffers. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 15/913529 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 15/005 (20130101) Original (OR) Class G06T 2200/04 (20130101) Pictorial Communication, e.g Television H04N 13/351 (20180501) H04N 13/398 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573605 | Tehranipoor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); The University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); The University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Mark M. Tehranipoor (Gainesville, Florida); Domenic J. Forte (Gainesville, Florida); Navid Asadizanjani (Gainesville, Florida); Qihang Shi (Farmington, Connecticut) |
| ABSTRACT | A method of assessing vulnerability of Integrated Circuit (IC) can include: preparing a list of logic nets of the IC; obtaining rectangular segments from the logic nets; finding a milling exclusion area based on a covering wire; and superimposing the found milling exclusion area onto the rectangular segments of the logic nets. The milling exclusion area is an area that microprobing attack does not succeed without cutting off at least one of the rectangular segments. |
| FILED | Tuesday, December 12, 2017 |
| APPL NO | 15/838647 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2851 (20130101) Electric Digital Data Processing G06F 21/60 (20130101) G06F 21/70 (20130101) G06F 21/87 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/00 (20130101) H01L 23/57 (20130101) Original (OR) Class H01L 23/576 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573944 | McKay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ian Salmon McKay (Seattle, Washington); Ruaridh R. Macdonald (London, United Kingdom); Thomas B. Milnes (Beverly, Massachusetts) |
| ABSTRACT | Provided is a method for generating an electrical current. The method includes: introducing water between the anode and at least one cathode of an electrochemical cell, to form an electrolyte; anaerobically oxidizing aluminum or an aluminum alloy at the anode; and electrochemically reducing water at the at least one cathode. The electrochemical cell includes: a plurality of electrode stacks, each electrode stack comprising an anode including the aluminum or aluminum alloy, and at least one cathode configured to be electrically coupled to the anode; one or more physical separators between each electrode stack adjacent to the cathode; a housing configured to hold the electrode stacks, the electrolyte, and the physical separators; and a water injection port in the housing. When the cell is in operation, the concentration of aluminum species in the electrolyte is maintained between at least 0.01 M to at most 0.7 M. |
| FILED | Tuesday, August 07, 2018 |
| APPL NO | 16/057186 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/463 (20130101) H01M 4/9041 (20130101) H01M 12/02 (20130101) H01M 12/04 (20130101) Original (OR) Class H01M 2004/027 (20130101) H01M 2004/8689 (20130101) H01M 2300/0014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573994 | Duva et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Conner Duva (Enfield, Connecticut); Jorge E. Hidalgo (Suffield, Connecticut) |
| ABSTRACT | A backshell assembly for a bulkhead electrical connector includes a lug defining a central lug bore, a nut defining a central nut bore, and a ring defining a central ring bore. The lug is configured to be coupled to the bulkhead electrical connector, the nut is configured to be coupled to the lug, and the ring is configured to be retained by the nut at least partially within at least one of the central lug bore and the central nut bore. A wire assembly to be coupled to the bulkhead electrical connector includes electromagnetic shielding, and such electromagnetic shielding is configured to be electrically grounded to the bulkhead electrical connector via the backshell assembly. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 15/962901 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 16/0215 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/502 (20130101) H01R 13/622 (20130101) Original (OR) Class H01R 13/6397 (20130101) H01R 13/6582 (20130101) H01R 13/6593 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574097 | Bergsrud et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Corey Alexis Marvin Bergsrud (Bloomington, Indiana); Alex John Zellner (Terre Haute, Indiana) |
| ABSTRACT | Systems and related methods are provided for improving cognitive function of a wireless power system designer and simulate various aspects of a wireless power system as an aid in making design selections in a tradeoff environment. Various embodiment enable such improved cognitive function by providing machine instructions that generate various graphical user interfaces which enable the wireless power system designer to visualize, compare, select, and change a variety of independent and dependent variables pertaining to a plurality of potential wireless power systems, a plurality of potential diodes, and a plurality of potential coplanar striplines for use in a plurality of operational environments as desired by the wireless power system designer. Aspects of various embodiments display design constraint warnings thereby providing visual display of design space solutions that do not violate various design constraints. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/917248 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/27 (20160201) H02J 50/40 (20160201) H02J 50/70 (20160201) H02J 50/80 (20160201) H02J 50/90 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574110 | Long et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAUNCHPOINT TECHNOLOGIES, INC. (Goleta, California) |
| ASSIGNEE(S) | LAUNCHPOINT TECHNOLOGIES, INC. (Goleta, California) |
| INVENTOR(S) | Geoffrey Alan Long (Montara, California); Bradley E. Paden (Goleta, California); Michael Richard Ricci (Camarillo, California); David Brian Paden (Goleta, California); Jonathan Gordon Sugar (Ventura, California) |
| ABSTRACT | A lightweight and efficient electrical machine element including a method of manufacture providing a stator winding for an electric machine which has a large portion of its volume containing electrically conductive strands and a small portion of its volume containing of an encapsulant material. The stator winding includes winding of a first phase by shaping a portion of a bundle of conductive strands into an overlapping, multi-layer arrangement. Winding of successive phases occurs with further bundles of conductor strands around the preceding phases constructed into similar overlapping, multi-layer arrangements. The multiple phases are impregnated with the encapsulant material using dies to press the bundles into a desired form while expelling excess encapsulant prior to the curing of the encapsulant material. The encapsulated winding is removed from the dies after the encapsulant has cured. The encapsulant coating on the strands may be activated using either heat or solvent. The stator winding may be pressed into a form which has cooling channels which increase the surface area, thus enhancing convective cooling, heat dissipation, and the electrical machine's efficiency. |
| FILED | Monday, May 02, 2016 |
| APPL NO | 15/143931 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 3/02 (20130101) H02K 3/04 (20130101) H02K 3/24 (20130101) H02K 3/28 (20130101) Original (OR) Class H02K 3/30 (20130101) H02K 3/47 (20130101) H02K 15/12 (20130101) H02K 15/0478 (20130101) H02K 21/24 (20130101) H02K 2213/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574183 | Valdes-Garcia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alberto Valdes-Garcia (Chappaqua, New York); Bodhisatwa Sadhu (Fishkill, New York) |
| ABSTRACT | A voltage controlled oscillator (VCO), a method of designing a voltage controlled oscillator, and a design structure comprising a semiconductor substrate including a voltage controlled oscillator are disclosed. In one embodiment, the VCO comprises an LC tank circuit for generating an oscillator output at an oscillator frequency, and an oscillator core including cross-coupled semiconductor devices to provide feedback to the tank circuit. The VCO further comprises a supply node, a tail node, and a noise by-pass circuit connected to the supply and tail nodes, in parallel with the tank circuit and the oscillator core. The by-pass circuit forms a low-impedance path at a frequency approximately twice the oscillator frequency to at least partially immunize the oscillator core from external noise and to reduce noise contribution from the cross-coupled semiconductor devices. |
| FILED | Wednesday, August 01, 2018 |
| APPL NO | 16/052192 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 17/505 (20130101) G06F 17/5045 (20130101) G06F 17/5063 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 1/00 (20130101) H03B 5/1212 (20130101) Original (OR) Class H03B 5/1215 (20130101) H03B 5/1228 (20130101) H03B 5/1243 (20130101) H03B 5/1281 (20130101) H03B 2200/009 (20130101) H03B 2200/0038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574240 | Jenkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Keith A. Jenkins (Sleepy Hollow, New York); Peilin Song (Lagrangeville, New York); James H. Stathis (Poughquag, New York); Franco Stellari (Waldwick, New Jersey) |
| ABSTRACT | An electronic apparatus for testing an integrated circuit (IC) that includes a ring oscillator is provided. The apparatus configures the ring oscillator to produce oscillation at a first frequency and configures the ring oscillator to produce oscillation at a second frequency. The apparatus then compares the second frequency with an integer multiple of the first frequency to determine a resistive voltage drop between a voltage applied to the IC and a local voltage at the ring oscillator. The ring oscillator has a chain of inverting elements forming a long ring and a short ring. The ring oscillator also has an oscillation selection circuit that is configured to disable the short ring so that the ring oscillator produces a fundamental oscillation based on signal propagation through the long ring and enable the short ring so that the ring oscillator produces a harmonic oscillation based on a signal propagation through the short ring and the long ring. |
| FILED | Tuesday, February 28, 2017 |
| APPL NO | 15/445587 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2824 (20130101) G01R 31/2851 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 1/00 (20130101) H03B 5/12 (20130101) H03B 5/30 (20130101) H03B 5/36 (20130101) H03B 5/1215 (20130101) Pulse Technique H03K 3/0315 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 1/00 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574288 | Dafesh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Philip Dafesh (Manhattan Beach, California); Phillip Brian Hess (Venice, California) |
| ABSTRACT | Under one aspect, a method is provided for processing a received signal, the received signal including a desired signal and an interference signal that spectrally overlaps the desired signal. The method can include obtaining an amplitude of the received signal. The method also can include obtaining an average amplitude of the received signal based on at least one prior amplitude of the received signal. The method also can include subtracting the amplitude from the average amplitude to obtain an amplitude residual. The method also can include, based upon an absolute value of the amplitude residual being less than or equal to a first threshold, inputting the received signal into an interference suppression algorithm so as to generate a first output including the desired signal with reduced contribution from the interference signal. |
| FILED | Friday, October 27, 2017 |
| APPL NO | 15/796453 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Transmission H04B 1/719 (20130101) H04B 1/1027 (20130101) H04B 1/1036 (20130101) H04B 1/7107 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574525 | Narain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vencore Labs, Inc. (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | Perspecta Labs Inc. (Basking Ridge, New Jersey) |
| INVENTOR(S) | Sanjai Narain (Basking Ridge, New Jersey); Brian Coan (Basking Ridge, New Jersey); Jon Kirsch (Basking Ridge, New Jersey) |
| ABSTRACT | A first controller in a distributed network obtains, concurrently with a second controller in the distributed network, a system requirement and a message from a logical bus. The first controller and the second controller are communicatively coupled to the logical bus, and the first controller is communicatively coupled to a first portion of the network components and the second controller is communicatively coupled to a second portion. A processor associated with the first controller solves, concurrently with the second controller, the system requirement and the solving includes applying a solver to generate new configurations of the network components. The new configurations generated by the first controller are identical to the new configurations generated by the second controller. The first controller extracts configurations relevant to the first portion of the network components and applies the configurations to the first portion of the network components. |
| FILED | Thursday, June 30, 2016 |
| APPL NO | 15/199212 |
| ART UNIT | 2459 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/403 (20130101) H04L 41/0813 (20130101) H04L 41/0823 (20130101) H04L 41/0873 (20130101) H04L 41/0893 (20130101) Original (OR) Class H04L 63/20 (20130101) H04L 67/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574688 | Hagelstrom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Eden Praire, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan L. Hagelstrom (Chaska, Minnesota); Ranga S. Ramanujan (Medina, Minnesota); Nathan E. Bahr (Eden Prairie, Minnesota) |
| ABSTRACT | A method of cyber-attack protection is provided. The method includes receiving one or more internet group management protocol (IGMP) membership report messages on one or more ports of a network switch. A table is maintained associating each of the one or more ports to the one or more group addresses of which any hosts coupled to that port are members. An IGMP group leave message is received at a first port of the network switch. A group address in the group leave message is compared to all group addresses associated in the table with the first port. If the group address in the group leave message does not match any group address associated with the first port, the group leave message is dropped without being acted on in accordance with IGMP. |
| FILED | Thursday, June 01, 2017 |
| APPL NO | 15/611106 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 61/2069 (20130101) H04L 63/1433 (20130101) H04L 63/1441 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10575113 | Badler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Norman I. Badler (Haverford, Pennsylvania); Pengfei Huang (Bellevue, Washington); Mubbasir Kapadia (Baden, Switzerland) |
| ABSTRACT | Methods and systems for sound propagation and perception for autonomous agents in dynamic environments are described. Adaptive discretization of continuous sound signals allows one to obtain a minimal, yet sufficient sound packet representation (SPR) for human-like perception, and a hierarchical clustering scheme to facilitate approximate perception. Planar sound propagation of discretized sound signals exhibit acoustic properties such as attenuation, reflection, refraction, and diffraction, as well as multiple convoluted sound signals. Agent-based sound perceptions using hierarchical clustering analysis that accommodates natural sound degradation due to audio distortion facilitate approximate human-like perception. |
| FILED | Thursday, March 01, 2018 |
| APPL NO | 15/909054 |
| ART UNIT | 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/18 (20130101) Stereophonic Systems H04S 7/30 (20130101) Original (OR) Class H04S 2400/11 (20130101) H04S 2420/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10569330 | King et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Forge Nano, Inc. (Louisville, Colorado) |
| ASSIGNEE(S) | FORGE NANO, INC. (Louisville, Colorado) |
| INVENTOR(S) | David M. King (Sudbury, Massachusetts); Paul Lichty (Louisville, Colorado) |
| ABSTRACT | The present invention provides various passive electronic components comprising a layer of coated particles, and methods for producing and using the same. Some of the passive electronic components of the invention include, but are not limited to conductors, resistors, current collectors, capacitors, piezoelectronic devices, inductors and transformers. The present invention also provides energy storage devices and electrode layers for such energy storage devices having passive, electrically-conductive particles coated with one or more thin film materials. |
| FILED | Wednesday, September 12, 2018 |
| APPL NO | 16/129642 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/00 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) B22F 1/0018 (20130101) B22F 1/025 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/34 (20130101) C23C 16/40 (20130101) C23C 16/0236 (20130101) C23C 16/403 (20130101) C23C 16/442 (20130101) C23C 16/4417 (20130101) C23C 16/45525 (20130101) C23C 16/45555 (20130101) C23C 18/1216 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/008 (20130101) H01G 4/30 (20130101) H01G 4/33 (20130101) H01G 4/0085 (20130101) H01G 4/1227 (20130101) H01G 11/24 (20130101) H01G 11/30 (20130101) H01G 11/46 (20130101) H01G 11/50 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569363 | El-Dasher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Bassem S. El-Dasher (Livermore, California); Andrew Bayramian (Manteca, California); James A. Demuth (Mountain View, California); Joseph C. Farmer (Tracy, California); Sharon G. Torres (Livermore, California) |
| ABSTRACT | A system is disclosed for performing an Additive Manufacturing (AM) fabrication process on a powdered material forming a substrate. The system may make use of a diode array for generating an optical signal sufficient to melt a powdered material of the substrate. A mask may be used for preventing a first predetermined portion of the optical signal from reaching the substrate, while allowing a second predetermined portion to reach the substrate. At least one processor may be used for controlling an output of the diode array. |
| FILED | Tuesday, May 03, 2016 |
| APPL NO | 15/145402 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 2003/1056 (20130101) B22F 2003/1057 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/042 (20151001) B23K 26/066 (20151001) B23K 26/144 (20151001) B23K 26/342 (20151001) Original (OR) Class B23K 26/0622 (20151001) B23K 26/0643 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 80/00 (20141201) Alloys C22C 32/0026 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569480 | Sander et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Jonathan Samuel Sander (Zurich, Switzerland); Yet-Ming Chiang (Weston, Massachusetts); Randall Morgan Erb (Newton, Massachusetts) |
| ABSTRACT | The use of magnetic fields in the production of porous articles is generally described. Certain embodiments comprise exposing a matrix to a magnetic field such that particles within the matrix form one or more elongated regions (e.g., one or more regions in which the particles chain). In some embodiments, after the magnetic field has been applied, the particles and/or a liquid within the matrix can be at least partially removed. Removal of the particles and/or the liquid can leave behind anisotropic pores within the remainder of the matrix material. |
| FILED | Friday, October 02, 2015 |
| APPL NO | 14/874253 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 67/202 (20130101) Original (OR) Class Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/3468 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/447 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/587 (20130101) H01M 4/625 (20130101) H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570010 | Finnegan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Patrick Sean Finnegan (Albuquerque, New Mexico); Cody M. Washburn (Albuquerque, New Mexico); David Bruce Burckel (Albuquerque, New Mexico); David R. Wheeler (Albuquerque, New Mexico); Timothy N. Lambert (Albuquerque, New Mexico); Lee Taylor Massey (Livermore, California); Jennifer Marie Strong (Rio Rancho, New Mexico); Christopher Dyck (Albuquerque, New Mexico) |
| ABSTRACT | The various technologies presented herein relate to formation of carbon micromechanical systems (CMEMS), wherein the CMEMS comprise multiple layers of carbon structures and are formed using a plurality of photoresist precursors that are processed to form carbon. The various embodiments can be utilized in producing a plurality of CMEMS with full production level fabrication, e.g., 6 inch wafers can be processed. A pyrolyzed layer of carbon is lithographically defined after pyrolysis, wherein the post-pyrolysis etch process can produce carbon structures having repeatable and accurate device geometries, with straight sidewalls. A sacrificial layer can be applied to facilitate separation of a first carbon layer from a second carbon layer, wherein, upon pyrolysis to form the second carbon layer and lithography thereof, the sacrificial layer is removed to form a CMEMS comprising a first carbon layer (e.g., comprising bottom contacts) located beneath a second carbon layer (e.g., a mechanical layer). |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/624928 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00476 (20130101) Original (OR) Class B81C 2201/0107 (20130101) B81C 2201/0109 (20130101) B81C 2201/0132 (20130101) B81C 2201/0197 (20130101) B81C 2201/0198 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570027 | Wai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chien M. Wai (Seattle, Washington); Horng-Bin Pan (Seattle, Washington); Gary A. Gill (Richland, Washington); Li-Jung Kuo (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington); University of Idaho (Moscow, Idaho) |
| INVENTOR(S) | Chien M. Wai (Seattle, Washington); Horng-Bin Pan (Seattle, Washington); Gary A. Gill (Richland, Washington); Li-Jung Kuo (Richland, Washington) |
| ABSTRACT | A fiber comprising a carbon chain backbone and amidoxime, carboxylate, and nitrile pendant groups. The fiber may be used for removing uranium from seawater and toxic metals from drinking water. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/179766 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/264 (20130101) B01J 20/28023 (20130101) B01J 20/28033 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/285 (20130101) Original (OR) Class C02F 2101/10 (20130101) C02F 2103/08 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570146 | Makriyannis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Alexandros Makriyannis (Watertown, Massachusetts); Vidyanand G Shukla (Boston, Massachusetts); Shakiru O Alapafuja (Willimantic, Connecticut) |
| ABSTRACT | Disclosed are compounds that may be used to inhibit the action of fatty acid amide hydrolase (FAAH), monoacylglycerol lipase (MAGL) or dual FAAH/MAGL. More particularly, compounds of formula II have utility in a variety of therapeutic uses such as treatment of pain, inflammation, neuropathy, or appetite disorder. |
| FILED | Friday, July 24, 2015 |
| APPL NO | 15/328428 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 205/04 (20130101) C07D 211/16 (20130101) C07D 211/46 (20130101) C07D 211/54 (20130101) C07D 213/64 (20130101) C07D 213/74 (20130101) C07D 213/84 (20130101) C07D 213/85 (20130101) C07D 215/12 (20130101) C07D 233/61 (20130101) C07D 241/04 (20130101) C07D 257/04 (20130101) C07D 295/26 (20130101) C07D 295/195 (20130101) C07D 401/06 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/06 (20130101) C07D 405/06 (20130101) C07D 487/08 (20130101) C07D 491/107 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570384 | Spodsberg |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Nikolaj Spodsberg (Bagsvaerd, Denmark) |
| ABSTRACT | The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Wednesday, September 05, 2018 |
| APPL NO | 16/122230 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/248 (20130101) C12N 9/2482 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) Enzymes C12Y 302/01008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570400 | Lajoie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Marc J. Lajoie (Cambridge, Massachusetts); Christopher J. Gregg (Roslindale, Massachusetts); Joshua A. Mosberg (Cambridge, Massachusetts); George M. Church (Brookline, Massachusetts) |
| ABSTRACT | A method of introducing a nucleic acid sequence into a cell is provided where the cell has impaired or inhibited or disrupted DnaG primase activity or impaired or inhibited or disrupted DnaB helicase activity, or larger or increased gaps or distance between Okazaki fragments or lowered or reduced frequency of Okazaki fragment initiation, or the cell has increased single stranded DNA (ssDNA) on the lagging strand of the replication fork including transforming the cell through recombination with a nucleic acid oligomer. |
| FILED | Tuesday, February 07, 2017 |
| APPL NO | 15/426527 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) C12N 15/72 (20130101) Original (OR) Class C12N 15/102 (20130101) C12N 15/1024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570404 | Ohlrogge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | John B. Ohlrogge (Okemos, Michigan); Christoph Benning (East Lansing, Michigan); Wei Ma (Lansing, Michigan); Que Kong (Lansing, Michigan) |
| ABSTRACT | The application describes stabilized WRINKLED1 transcription factors, as well as nucleic acids, and expression cassettes that encode and express such stabilized WRINKLED1 transcription factors and that are useful for increasing production of oils in plants and seeds. |
| FILED | Thursday, June 30, 2016 |
| APPL NO | 15/199357 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570415 | Doudna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Jillian Banfield (Berkeley, California); David Burstein (Berkeley, California); Lucas Benjamin Harrington (Berkeley, California); Steven C. Strutt (Berkeley, California) |
| ABSTRACT | The present disclosure provides CasX proteins, nucleic acids encoding the CasX proteins, and modified host cells comprising the CasX proteins and/or nucleic acids encoding same. CasX proteins are useful in a variety of applications, which are provided. The present disclosure provides CasX guide RNAs that bind to and provide sequence specificity to the CasX proteins, nucleic acids encoding the CasX guide RNAs, and modified host cells comprising the CasX guide RNAs and/or nucleic acids encoding same. CasX guide RNAs are useful in a variety of applications, which are provided. The present disclosure provides archaeal Cas9 polypeptides and nucleic acids encoding same, as well as their associated archaeal Cas9 guide RNAs and nucleic acids encoding same. |
| FILED | Friday, August 03, 2018 |
| APPL NO | 16/054513 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 19/00 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/1007 (20130101) C12N 9/1025 (20130101) C12N 15/52 (20130101) C12N 15/62 (20130101) C12N 15/74 (20130101) C12N 15/85 (20130101) C12N 15/88 (20130101) C12N 15/113 (20130101) C12N 15/8509 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2740/13043 (20130101) C12N 2740/16043 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570431 | Quinlan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Jason Quinlan (Woodland, California); Feng Xu (Davis, California); Matthew Sweeney (Sacramento, California) |
| ABSTRACT | The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and a heterocyclic compound. The present invention also relates to methods of using the compositions. |
| FILED | Friday, August 03, 2018 |
| APPL NO | 16/054118 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/37 (20130101) C07K 14/38 (20130101) C07K 14/385 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) C12N 9/2437 (20130101) C12N 9/2445 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/002 (20130101) C12P 5/02 (20130101) C12P 5/026 (20130101) C12P 7/10 (20130101) C12P 7/26 (20130101) C12P 7/28 (20130101) C12P 7/40 (20130101) C12P 13/04 (20130101) C12P 19/02 (20130101) C12P 19/12 (20130101) C12P 19/14 (20130101) Original (OR) Class C12P 2201/00 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 302/01004 (20130101) C12Y 302/01021 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570502 | Soules et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security (Livermore, California) |
| INVENTOR(S) | Thomas F. Soules (Livermore, California); Raymond J. Beach (Livermore, California); Scott C. Mitchell (Tracy, California); Gary DeBell (Los Altos, California) |
| ABSTRACT | In one embodiment, a method for forming an alkali resistant coating includes forming a first oxide material above a substrate and forming a second oxide material above the first oxide material to form a multilayer dielectric coating, wherein the second oxide material is on a side of the multilayer dielectric coating for contacting an alkali. In another embodiment, a method for forming an alkali resistant coating includes forming two or more alternating layers of high and low refractive index oxide materials above a substrate, wherein an innermost layer of the two or more alternating layers is on an alkali-contacting side of the alkali resistant coating, and wherein the innermost layer of the two or more alternating layers comprises at least one of: alumina, zirconia, and hafnia. |
| FILED | Monday, November 03, 2014 |
| APPL NO | 14/531875 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/08 (20130101) Original (OR) Class C23C 14/10 (20130101) C23C 14/46 (20130101) C23C 14/081 (20130101) C23C 14/082 (20130101) C23C 14/083 (20130101) C23C 14/3442 (20130101) C23C 16/401 (20130101) C23C 16/403 (20130101) C23C 16/405 (20130101) C23C 16/45555 (20130101) C23C 28/04 (20130101) C23C 28/042 (20130101) C23C 28/42 (20130101) C23C 28/44 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0346 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24942 (20150115) Y10T 428/24975 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571356 | Hun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Diana E. Hun (Lenoir City, Tennessee); Brenda A. Smith (Knoxville, Tennessee); Linda A. Lewis (Andersonville, Tennessee) |
| ABSTRACT | Provided is a Fluorescent Air Leakage Detection (FALD) system and method for locating a defect in an enclosure that uses a nontoxic fluorescent solution as a marker. The solution is aerosolized with an atomizing device and guided to defects by a gas pressure modifying device. Defects are visually located by surveying the enclosure with an ultraviolet or visible light source and identifying a location where accumulated solution fluoresces. |
| FILED | Wednesday, September 13, 2017 |
| APPL NO | 15/703154 |
| ART UNIT | 2854 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571442 | Lenzner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Matthias Lenzner (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthias Lenzner (Tucson, Arizona) |
| ABSTRACT | A technique and device to determine the spectrum of electromagnetic radiation in a certain range of wavelengths comprising: splitting said radiation into more than one beam; let these beams counter-propagate in a Sagnac-type ring interferometer; and imprinting a wavelength-dependent angular tilt onto the wavefront of each beam by at least one dispersive element which preferably is a transmission grating or grism; and re-combining the multiple beams on a detector that exhibits spatial resolution and can therefore resolve the fringes formed by interference; and perform the mathematical operations to determine the spectrum of said radiation from the obtained interferogram, wherein the dispersive element is mounted on a stage providing linear and/or rotational movement. |
| FILED | Wednesday, November 02, 2016 |
| APPL NO | 15/341104 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/00 (20130101) G01J 3/45 (20130101) G01J 3/1804 (20130101) G01J 3/4532 (20130101) G01J 3/4537 (20130101) G01J 2003/1208 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0004 (20130101) Original (OR) Class G01N 2033/0093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571453 | Cooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Fred Paul Mark Jjunju (West Lafayette, Indiana); Anyin Li (West Lafayette, Indiana); Iman S. Roqan (Thuwal, Saudi Arabia) |
| ABSTRACT | The invention generally relates to methods of analyzing crude oil. In certain embodiments, methods of the invention involve obtaining a crude oil sample, and subjecting the crude oil sample to mass spectrometry analysis. In certain embodiments, the method is performed without any sample pre-purification steps. |
| FILED | Wednesday, December 26, 2018 |
| APPL NO | 16/232574 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/724 (20130101) G01N 30/7266 (20130101) G01N 33/2823 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/04 (20130101) H01J 49/10 (20130101) H01J 49/16 (20130101) H01J 49/0031 (20130101) H01J 49/164 (20130101) H01J 49/165 (20130101) H01J 49/168 (20130101) H01J 49/0445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571460 | Sussman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Michael R. Sussman (Cross Plains, Wisconsin); J. Leon Shohet (Madison, Wisconsin); Faraz A. Choudhury (Madison, Wisconsin); Joshua M. Blatz (Monona, Wisconsin); Benjamin B. Minkoff (Madison, Wisconsin); Daniel I. Benjamin (Madison, Wisconsin) |
| ABSTRACT | This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule. |
| FILED | Friday, May 19, 2017 |
| APPL NO | 15/600352 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 2219/0809 (20130101) B01J 2219/0894 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 33/50 (20130101) Original (OR) Class G01N 33/487 (20130101) G01N 33/6848 (20130101) G01N 2333/765 (20130101) G01N 2333/90216 (20130101) G01N 2333/91215 (20130101) G01N 2440/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571535 | Takayasu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Makoto Takayasu (Lexington, Massachusetts) |
| ABSTRACT | A novel system and method for detecting a quench of a superconducting conductor and detecting abnormal behavior of a superconducting conductor using acoustic sensor technology in the coolant of a superconducting cable and/or magnet is disclosed. This system and method is not only limited to use for superconductors, but also may be used for any device disposed in liquid and gas. Acoustic sensors are installed along a coolant space of a superconducting conductor and monitor coolant conditions. By monitoring acoustic changes, temperature changes or coolant flow disruption can be detected very quickly by an acoustic sensor array. By disposition of the acoustic sensor array in a coolant flow channel, the acoustic sensor system can quickly detect a local condition, such as the thermal status (temperature) of a superconducting cable and magnet with precise spatial resolution. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/012183 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/3538 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/14 (20130101) G01N 29/2418 (20130101) G01N 2201/088 (20130101) G01N 2291/106 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/3804 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 6/02 (20130101) H01F 6/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571675 | Reed |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Integrated Dynamic Electron Solutions, Inc. (Pleasanton, California) |
| ASSIGNEE(S) | Integrated Dynamic Electron Solutions, Inc. (Pleasanton, California) |
| INVENTOR(S) | Bryan Reed (San Leandro, California) |
| ABSTRACT | Methods and systems for temporal compressive sensing are disclosed, where within each of one or more sensor array data acquisition periods, one or more sensor array measurement datasets comprising distinct linear combinations of time slice data are acquired, and where mathematical reconstruction allows for calculation of accurate representations of the individual time slice datasets. |
| FILED | Thursday, December 27, 2018 |
| APPL NO | 16/233597 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/225 (20130101) Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 11/003 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/28 (20130101) H01J 37/222 (20130101) H01J 37/265 (20130101) H01J 2237/221 (20130101) H01J 2237/226 (20130101) H01J 2237/262 (20130101) H01J 2237/2802 (20130101) H01J 2237/24455 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571803 | Darling et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Seth B. Darling (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Yu-Chih Tseng (Hamilton, Canada) |
| ABSTRACT | Simplified methods of multiple-patterning photolithography using sequential infiltration synthesis to modify the photoresist such that it withstands plasma etching better than unmodified resist and replaces one or more hard masks and/or a freezing step in MPL processes including litho-etch-litho-etch photolithography or litho-freeze-litho-etch photolithography. |
| FILED | Monday, June 12, 2017 |
| APPL NO | 15/620318 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class G03F 7/405 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0273 (20130101) H01L 21/3065 (20130101) H01L 21/3081 (20130101) H01L 21/3086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572263 | Fleischer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Bruce M. Fleischer (Bedford Hills, New York); Thomas Winters Fox (Hopewell Junction, New York); Arpith C. Jacob (Dobbs Ferry, New York); Hans Mikael Jacobson (White Plains, New York); Ravi Nair (Briarcliff Manor, New York); Kevin John Patrick O'Brien (Yorktown Heights, New York); Daniel Arthur Prener (Croton-on-Hudson, New York) |
| ABSTRACT | A processor core includes a storage device which stores a composite very large instruction word (VLIW) instruction, an instruction unit which obtains the composite VLIW instruction from the storage device and decodes the composite VLIW instruction to determine an operation to perform, and a composite VLIW instruction execution unit which executes the decoded composite VLIW instruction to perform the operation. |
| FILED | Thursday, March 31, 2016 |
| APPL NO | 15/086947 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3836 (20130101) G06F 9/3853 (20130101) Original (OR) Class G06F 9/30065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572659 | Ferragut et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Erik M. Ferragut (Oak Ridge, Tennessee); Jason A. Laska (Oak Ridge, Tennessee) |
| ABSTRACT | A cyber-security threat detection system and method stores physical data measurements from a cyber-physical system and extracts synchronized measurement vectors synchronized to one or more timing pulses. The system and method synthesizes data integrity attacks in response to the physical data measurements and applies alternating parametrized linear and non-linear operations in response to the synthesized data integrity attacks. The synthesis renders optimized model parameters used to detect multiple cyber-attacks. |
| FILED | Tuesday, September 19, 2017 |
| APPL NO | 15/709176 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/57 (20130101) G06F 21/552 (20130101) Original (OR) Class G06F 21/554 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572786 | Smartt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Keith Tolk (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Keith Tolk (Albuquerque, New Mexico) |
| INVENTOR(S) | Heidi A. Smartt (Albuquerque, New Mexico); William C. Sweatt (Albuquerque, New Mexico); Michael B. Sinclair (Albuquerque, New Mexico); Michael McDaniel (Albuquerque, New Mexico); Juan A. Romero (Bayfield, Colorado); Keith Tolk (Albuquerque, New Mexico) |
| ABSTRACT | A reflective particle tag reader system includes a read head assembly having a camera, illuminators, and a rigid frame portion for supporting the camera and the illuminators. The illuminators illuminate a focal point located opposite the camera where a reflective particle tag is placed. A computer in data communication with the camera receives and store images of the reflective particle tag that are acquired by the camera. The computer is programmed to process video images and to quantify a positional alignment parameter and an angular alignment parameter of the reader with respect to the reflective particle tag. A rapid burst of image frames is obtained in response to the positional alignment and the angular alignment parameters being within a predetermined tolerance and identity of the reflective tag is established between a first image set and a second image set. |
| FILED | Tuesday, September 25, 2018 |
| APPL NO | 16/140694 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/06112 (20130101) Original (OR) Class G06K 19/06131 (20130101) G06K 2019/0629 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573404 | Reed et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Jennifer Leanne Reed (Madison, Wisconsin); Matthew Ray Long (Madison, Wisconsin) |
| ABSTRACT | Provided are systems and methods for accurately determining flux distribution in organisms or cells without use of metabolic flux analysis data. The methods include estimating flux distributions in multiple reference strains (variants of a parental strain) using experimentally determined extracellular flux data from the reference strains, and determining a flux distribution for the parental strain from the estimated flux distributions for the reference strains and from experimentally measured extracellular fluxes for the parental strain. The systems are configured for carrying out the methods. |
| FILED | Thursday, February 04, 2016 |
| APPL NO | 15/015561 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573439 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Yanfeng Jiang (Minneapolis, Minnesota) |
| ABSTRACT | The disclosure describes multilayer hard magnetic materials including at least one layer including α″-Fe16N2 and at least one layer including α″-Fe16(NxZ1-x)2 or a mixture of α″-Fe16N2 and α″-Fe16Z2, where Z includes at least one of C, B, or O, and x is a number greater than zero and less than one. The disclosure also describes techniques for forming multilayer hard magnetic materials including at least one layer including α″-Fe16N2 and at least one layer including α″-Fe16(NxZ1-x)2 or a mixture of α″-Fe16N2 and α″-Fe16Z2 using chemical vapor deposition or liquid phase epitaxy. |
| FILED | Wednesday, August 05, 2015 |
| APPL NO | 15/501697 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/34 (20130101) C23C 16/56 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/059 (20130101) Original (OR) Class H01F 41/22 (20130101) Dynamo-electric Machines H02K 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573547 | Trujillo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Joshua Joseph Trujillo (Belton, Missouri); Robert Allen Williams (Belton, Missouri) |
| ABSTRACT | An apparatus and method for facilitating the removal of layers from a die for an integrated circuit while maintaining the planarity of the surface of the die by avoiding rounding the corners and other edges of the die. A pocket is created in a sacrificial material, such that when the die is inserted into the pocket the edges of the die are contiguous with the walls of the pocket and a top surface of the die is coplanar with a top surface of the pocket. The sacrificial material may be the same material as the die. An adhesive substance is placed in the pocket, and the die is inserted into the pocket and against the adhesive substance which aids in retaining the die in the pocket. The layers may then be removed from the die and the sacrificial material around the die without rounding the edges of the die. |
| FILED | Monday, November 05, 2018 |
| APPL NO | 16/180734 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/6835 (20130101) Original (OR) Class H01L 21/30604 (20130101) H01L 21/30625 (20130101) H01L 2221/68313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573630 | Wilkerson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Brett P. Wilkerson (Austin, Texas); Milind Bhagavat (Cupertino, California); Rahul Agarwal (San Francisco, California); Dmitri Yudanov (Austin, Texas) |
| ABSTRACT | A three-dimensional integrated circuit includes a first die having a first geometry. The first die includes a first region that operates with a first power density and a second region that operates with a second power density. The first power density is less than the second power density. The first die includes first electrical contacts disposed in the first region on a first side of the first die along a periphery of the first die. The three-dimensional integrated circuit includes a second die having a second geometry. The second die includes second electrical contacts disposed on a first side of the second die. A stacked portion of the second die is stacked within the periphery of the first die and an overhang portion of the second die extends beyond the periphery of the first die. The second electrical contacts are aligned with and coupled to the first electrical contacts. |
| FILED | Friday, April 20, 2018 |
| APPL NO | 15/958169 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/481 (20130101) H01L 23/3675 (20130101) H01L 24/03 (20130101) H01L 24/05 (20130101) H01L 24/06 (20130101) H01L 24/08 (20130101) H01L 24/09 (20130101) H01L 25/18 (20130101) Original (OR) Class H01L 25/50 (20130101) H01L 2224/0557 (20130101) H01L 2224/03002 (20130101) H01L 2224/06179 (20130101) H01L 2224/06181 (20130101) H01L 2224/08146 (20130101) H01L 2224/09179 (20130101) H01L 2924/1431 (20130101) H01L 2924/1433 (20130101) H01L 2924/1434 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573869 | Mikhaylik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sion Power Corporation (Tucson, Arizona) |
| ASSIGNEE(S) | Sion Power Corporation (Tucson, Arizona) |
| INVENTOR(S) | Yuriy V. Mikhaylik (Tucson, Arizona); Michael G. Laramie (Tucson, Arizona); David Child (Tucson, Arizona) |
| ABSTRACT | Articles and methods for protection of electrodes in electrochemical cells, including protective material precursor layers for use in electrode protective structures, are provided. Certain embodiments relate to electrode protective structures that comprise protective material precursor layers that, upon direct contact with a liquid electrolyte, cause a reaction product to form between the material of the precursor layer and a component of the electrolyte. |
| FILED | Wednesday, June 06, 2018 |
| APPL NO | 16/001054 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1646 (20130101) H01M 2/1673 (20130101) H01M 2/1686 (20130101) Original (OR) Class H01M 4/62 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/382 (20130101) H01M 10/052 (20130101) H01M 10/056 (20130101) H01M 10/0525 (20130101) H01M 10/4235 (20130101) H01M 2004/027 (20130101) H01M 2200/00 (20130101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573889 | Thackeray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Michael M. Thackeray (Naperville, Illinois); Jason R. Croy (Plainfield, Illinois); Brandon R. Long (Plainfield, Illinois); Eungje Lee (Naperville, Illinois); Joong Sun Park (Woodridge, Illinois) |
| ABSTRACT | An electrode for a lithium-ion cell comprising a ‘layered-spinel’ composite oxide material is disclosed. The ‘layered-spinel’ can be a material of formula xLiMO2.(1−x)LiyM′zO4, wherein 0<x<1; LiMO2 is a lithium metal oxide having a layered structure in which M comprises one or more transition metals and optionally lithium, and has a combined average oxidation state of +3; and LiyM′zO4 is a lithium metal oxide having a spinel structure, 1≤y≤1.33, 1.66≤z≤2, and M′ comprises one or more transition metals, and has a combined average metal oxidation state in the range of about +3.5 to about +4. |
| FILED | Tuesday, December 29, 2015 |
| APPL NO | 14/982226 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 23/005 (20130101) C01G 45/1228 (20130101) C01G 45/1242 (20130101) C01G 51/42 (20130101) C01G 53/42 (20130101) C01G 53/50 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/32 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/485 (20130101) Original (OR) Class H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/623 (20130101) H01M 4/1315 (20130101) H01M 10/052 (20130101) H01M 2300/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573932 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Heng Yang (Pasadena, California); Nicholas J. Weadock (Pasadena, California); Brent T. Fultz (Pasadena, California); Bryce W. Edwards (Pasadena, California) |
| ABSTRACT | In an aspect, an electrochemical cell comprises: a positive electrode; a negative electrode, said negative electrode having an alloy having a composition comprising V; and an electrolyte; wherein an additive is provided in said electrolyte to form primary vanadate ions upon dissociation of said additive in said electrolyte; and wherein the electrochemical cell is a metal hydride battery. In some embodiments of this aspect, the alloy is configured to sorb hydrogen during charging of said electrochemical cell and desorb hydrogen during discharging of said electrochemical cell. In some embodiments of this aspect, the electrolyte has a pH selected from the range of 13 to 15. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 15/996380 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0003 (20130101) B22F 7/08 (20130101) B22F 7/08 (20130101) B22F 9/04 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) Alloys C22C 1/02 (20130101) C22C 1/045 (20130101) C22C 32/0026 (20130101) C22C 32/0031 (20130101) C22C 2200/00 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 11/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/32 (20130101) H01M 4/242 (20130101) H01M 4/383 (20130101) H01M 10/44 (20130101) H01M 10/345 (20130101) Original (OR) Class H01M 2300/0014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574056 | Wilches Bernal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Felipe Wilches Bernal (Albuquerque, New Mexico); Jason C. Neely (Albuquerque, New Mexico); Ricky James Concepcion (Albuquerque, New Mexico); Raymond H. Byrne (Albuquerque, New Mexico); Abraham Ellis (Albuquerque, New Mexico) |
| ABSTRACT | A system and method for control of dispatchable resources on an electrical power distribution grid is disclosed. The disclosed method provides improved response to power imbalance based on a communications signal independent of system frequency. The communication signal provides a feed-forward control of dispatchable power resources. A communications network is employed to generate a signal to dispatchable resources that a power imbalance has occurred. Due to fast response power transmission network interfaces associated with the dispatchable resources, the respective resources respond in significantly less time than feedback controlled conventional generators which depend on line frequency sensing. The rapid response mitigates the impact of power imbalances and enables greater penetrations of converter-interfaced power generation units such as renewable energy sources to be connected to the grid. |
| FILED | Tuesday, October 10, 2017 |
| APPL NO | 15/729334 |
| ART UNIT | 2115 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574461 | Hughes et al. |
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| FUNDED BY |
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| APPLICANT(S) | LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Richard John Hughes (Los Alamos, New Mexico); Jane Elizabeth Nordholt (Los Alamos, New Mexico); Charles Glen Peterson (Los Alamos, New Mexico); Kush T. Tyagi (Los Alamos, New Mexico); Christopher C. Wipf (Los Alamos, New Mexico); Raymond Thorson Newell (Santa Fe, New Mexico); Kevin P. McCabe (Los Alamos, New Mexico); Nicholas Dallmann (Los Alamos, New Mexico) |
| ABSTRACT | Message authenticators for quantum-secured communications facilitate low-latency authentication with assurances of security. Low-latency message authenticators are especially valuable in infrastructure systems where security and latency constraints are difficult to satisfy with conventional non-quantum cryptography. For example, a message transmitter receives a message and derives an authentication tag for the message based at least in part on an authenticator that uses one or more quantum keys. The message transmitter outputs the message and its authentication tag. A message receiver receives a message and authentication tag for the message. The message receiver derives a comparison tag for the message based at least in part on an authenticator that uses one or more quantum keys. The message receiver checks whether the message is authentic based on a comparison of the authentication tag and the comparison tag. In example implementations, the authenticator uses stream-wise cyclic redundancy code operations. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 15/026024 |
| ART UNIT | 2495 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0852 (20130101) H04L 9/3226 (20130101) Original (OR) Class H04L 63/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10568761 | Kulstad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Cooling Therapy, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | Advanced Cooling Therapy, Inc. (Chicago, Illinois) |
| INVENTOR(S) | Erik Kulstad (Dallas, Texas); Hugh Patrick Caherty (Canton, Michigan) |
| ABSTRACT | Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed. |
| FILED | Wednesday, December 21, 2016 |
| APPL NO | 15/386375 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2017/00084 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/12 (20130101) Original (OR) Class A61F 7/123 (20130101) A61F 2007/0054 (20130101) A61F 2007/0056 (20130101) A61F 2007/0093 (20130101) A61F 2007/0095 (20130101) A61F 2007/126 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568992 | Lipke et al. |
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| FUNDED BY |
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| APPLICANT(S) | Auburn University (Auburn, Alabama) |
| ASSIGNEE(S) | Auburn University (Auburn, Alabama) |
| INVENTOR(S) | Elizabeth A. Lipke (Auburn, Alabama); Wen Jun Seeto (Auburn, Alabama) |
| ABSTRACT | The present invention relates to the production of endothelialized matrices and materials from immature endothelial cells using substrates to which particular peptides have been grafted. The resultant substrates can be used to capture and support immature endothelial cells. Further, the methods and compositions of the present invention provide viable cell delivery platforms that allow for production and provision of endothelialized medical devices and implants, including vascular grafts, stents, shunts, and valves, endothelialized surfaces and channels for in vitro testing devices, including microfluidic chips, and materials that support vascularization such as for use in engineered tissues. The present invention includes novel methods required for the successful production of cellularized substrates, systems and components used for the same, and methods of using the resultant cell and tissue compositions. |
| FILED | Thursday, April 14, 2016 |
| APPL NO | 15/099582 |
| ART UNIT | 1676 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/227 (20130101) A61L 27/3683 (20130101) A61L 31/005 (20130101) A61L 31/16 (20130101) Original (OR) Class A61L 31/047 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 2533/30 (20130101) C12N 2533/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569197 | Green et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Alexander A. Green (Boston, Massachusetts); Mark C. Hersam (Wilmette, Illinois) |
| ABSTRACT | A method of separating carbon nanotubes by electronic type includes centrifuging a carbon nanotube composition in contact with a first fluid medium comprising a first density gradient; and separating the carbon nanotube composition into two or more separation fractions. The carbon nanotube composition comprises two or more non-ionic amphiphilic surface active components and a carbon nanotube population comprising double-walled carbon nanotubes having a semiconducting outer wall (s-DWCNTs), and double-walled carbon nanotubes having a metallic outer wall (m-DWCNTs). The two or more separation fractions comprise a first separation fraction comprising a carbon nanotube subpopulation comprising a higher percentage of s-DWCNTs than the carbon nanotube population, and a second separation fraction comprising a carbon nanotube subpopulation comprising a higher percentage of m-DWCNTs than the carbon nanotube population. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/296501 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Separation B01D 21/262 (20130101) Original (OR) Class Flotation; Differential Sedimentation B03D 3/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/172 (20170801) C01B 2202/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569876 | Chakravarthy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wichita State University (Wichita, Kansas) |
| ASSIGNEE(S) | Wichita State University (Wichita, Kansas) |
| INVENTOR(S) | Animesh Chakravarthy (Wichita, Kansas); Debasish Ghose (Karnataka, India) |
| ABSTRACT | This document generally describes a safe-passage guidance strategy developed in a relative velocity framework to enable a generic aerial robot execute a precision three-dimensional maneuver through a narrow orifice in a wall. The relative sizes of the robot and the orifice can be such that the orifice is only slightly larger than the robot. The orifice can be approximated as an elliptical shape, and analytical nonlinear guidance laws incorporating state-based switching can be derived. Guidance laws can be used to maneuver the robot through both fixed and moving orifices as well as in scenarios when the orifice is closing with time. |
| FILED | Monday, March 19, 2018 |
| APPL NO | 15/925312 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Original (OR) Class B64C 2201/141 (20130101) B64C 2201/146 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0011 (20130101) G05D 1/042 (20130101) G05D 1/0088 (20130101) G05D 1/101 (20130101) G05D 1/0808 (20130101) Traffic Control Systems G08G 5/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570361 | Weitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Universität Augsburg (Augsburg, Germany) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Universität Augsburg (Augsburg, Germany) |
| INVENTOR(S) | David A. Weitz (Bolton, Massachusetts); Thomas Franke (Augsburg, Germany); Achim Wixforth (Munich, Germany); Lothar Schmid (Augsburg, Germany); Jeremy Agresti (Richmond, California); Adam R. Abate (Daly City, California) |
| ABSTRACT | Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one set of embodiments, droplets may be sorted using surface acoustic waves. The droplets may contain cells or other species. In some cases, the surface acoustic waves may be created using a surface acoustic wave generator such as an interdigitated transducer, and/or a material such as a piezoelectric substrate. The piezoelectric substrate may be isolated from the microfluidic substrate except at or proximate the location where the droplets are sorted, e.g., into first or second microfluidic channels. At such locations, the microfluidic substrate may be coupled to the piezoelectric substrate (or other material) by one or more coupling regions. In some cases, relatively high sorting rates may be achieved, e.g., at rates of at least about 1,000 Hz, at least about 10,000 Hz, or at least about 100,000 Hz, and in some embodiments, with high cell viability after sorting. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 15/604085 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2400/0421 (20130101) B01L 2400/0436 (20130101) B01L 2400/0487 (20130101) B01L 2400/0496 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class C12M 47/04 (20130101) Pipe-line Systems; Pipe-lines F17D 3/01 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0391 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570374 | Singh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Ankur Singh (Ithaca, New York); Shalu Suri (Ithaca, New York); Todd Christopher McDevitt (Atlanta, Georgia); Hang Lu (Atlanta, Georgia); Andres Jose Garcia (Atlanta, Georgia) |
| ABSTRACT | The present invention provides for methods of isolating a stem cell or cell derived therefrom from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/148784 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0623 (20130101) C12N 5/0696 (20130101) Original (OR) Class C12N 2506/45 (20130101) C12N 2509/10 (20130101) C12N 2527/00 (20130101) C12N 2539/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570375 | Singh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Ankur Singh (Ithaca, New York); Shalu Suri (Ithaca, New York); Todd Christopher McDevitt (Atlanta, Georgia); Hang Lu (Atlanta, Georgia); Andres Jose Garcia (Atlanta, Georgia) |
| ABSTRACT | The present invention provides for methods of isolating a stem cell or cell derived therefrom from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/149918 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0623 (20130101) C12N 5/0696 (20130101) Original (OR) Class C12N 2506/45 (20130101) C12N 2509/10 (20130101) C12N 2527/00 (20130101) C12N 2539/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570397 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Deleware (Newark, Delaware) |
| ASSIGNEE(S) | University of Deleware (Newark, Delaware) |
| INVENTOR(S) | Kelvin Lee (Newark, Delaware); Abraham Lenhoff (Newark, Delaware); Kristin Valente (Plymouth Meeting, Pennsylvania); Nick Levy (Philadelphia, Pennsylvania); Yatin Gokarn (San Diego, California) |
| ABSTRACT | The invention relates a method for producing a stable recombinant protein, comprising growing a non-naturally occurring host cell in a culture medium to produce a recombinant protein, and making a composition comprising the recombinant protein and a polysorbate. The production of endogenous lipoprotein lipase by the host cell is reduced. The endogenous lipoprotein lipase is present in the composition in a small amount, and is capable of degrading the polysorbate. The invention also relates to the relevant host cells and compositions, and preparation thereof. |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/897290 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/39 (20130101) A61K 38/42 (20130101) A61K 38/44 (20130101) A61K 38/45 (20130101) A61K 38/52 (20130101) A61K 38/443 (20130101) A61K 38/482 (20130101) A61K 38/488 (20130101) A61K 38/1709 (20130101) A61K 38/1741 (20130101) A61K 38/1761 (20130101) A61K 38/1774 (20130101) A61K 38/4813 (20130101) A61K 47/26 (20130101) Peptides C07K 16/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/20 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/10 (20130101) C12N 2310/14 (20130101) C12N 2310/20 (20170501) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) C12P 21/005 (20130101) Enzymes C12Y 104/03013 (20130101) C12Y 111/01015 (20130101) C12Y 205/01018 (20130101) C12Y 207/04006 (20130101) C12Y 207/11001 (20130101) C12Y 301/01034 (20130101) C12Y 304/21 (20130101) C12Y 304/16005 (20130101) C12Y 304/23005 (20130101) C12Y 502/01008 (20130101) C12Y 503/04001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570415 | Doudna et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jennifer A. Doudna (Berkeley, California); Jillian Banfield (Berkeley, California); David Burstein (Berkeley, California); Lucas Benjamin Harrington (Berkeley, California); Steven C. Strutt (Berkeley, California) |
| ABSTRACT | The present disclosure provides CasX proteins, nucleic acids encoding the CasX proteins, and modified host cells comprising the CasX proteins and/or nucleic acids encoding same. CasX proteins are useful in a variety of applications, which are provided. The present disclosure provides CasX guide RNAs that bind to and provide sequence specificity to the CasX proteins, nucleic acids encoding the CasX guide RNAs, and modified host cells comprising the CasX guide RNAs and/or nucleic acids encoding same. CasX guide RNAs are useful in a variety of applications, which are provided. The present disclosure provides archaeal Cas9 polypeptides and nucleic acids encoding same, as well as their associated archaeal Cas9 guide RNAs and nucleic acids encoding same. |
| FILED | Friday, August 03, 2018 |
| APPL NO | 16/054513 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 19/00 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/1007 (20130101) C12N 9/1025 (20130101) C12N 15/52 (20130101) C12N 15/62 (20130101) C12N 15/74 (20130101) C12N 15/85 (20130101) C12N 15/88 (20130101) C12N 15/113 (20130101) C12N 15/8509 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2740/13043 (20130101) C12N 2740/16043 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570446 | Ju et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEE OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Zengmin Li (Flushing, New York); John Robert Edwards (St. Louis, Missouri); Yasuhiro Itagaki (New York, New York) |
| ABSTRACT | This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotide analogues which comprise unique labels attached to the nucleotide analogue through a cleavable linker, and a cleavable chemical group to cap the —OH group at the 3′-position of the deoxyribose. |
| FILED | Monday, November 26, 2018 |
| APPL NO | 16/200540 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/11 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) C07H 19/14 (20130101) C07H 21/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6872 (20130101) C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/117 (20130101) C12Q 2525/186 (20130101) C12Q 2525/186 (20130101) C12Q 2535/101 (20130101) C12Q 2535/101 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2563/107 (20130101) C12Q 2563/107 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570461 | Iqbal et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Samir M. Iqbal (Euless, Texas); Swati Goyal (Fremont, California); Young-Tae Kim (Arlington, Texas); Yuan Wan (Arlington, Texas); Mohammed A. I. Mahmood (Arlington, Texas); Umair J. M. Khan (Arlington, Texas) |
| ABSTRACT | In one aspect, methods of detecting tumor cells are described herein. In some embodiments, a method of detecting tumor cells comprises providing a device, the device comprising a substrate surface and a plurality of first aptamer probes attached to the substrate surface. The method further comprises contacting a plurality of cells with the plurality of first aptamer probes attached to the substrate surface; adhering one or more of the plurality of cells to the substrate surface; and measuring a non-uniformity parameter, a Hausdorff distance, a change in the number of pseudopods, and/or a shape of at least one adhered cell. In some cases, the method further comprises using the non-uniformity parameter, Hausdorff distance, change in the number of pseudopods, and/or shape of the adhered cell to identify the adhered cell as a tumor cell or a non-tumor cell. |
| FILED | Tuesday, November 27, 2018 |
| APPL NO | 16/201784 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) G01N 33/57492 (20130101) G01N 2333/71 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570494 | Hosek et al. |
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| FUNDED BY |
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| APPLICANT(S) | Persimmon Technologies, Corp. (Wakefield, Massachusetts) |
| ASSIGNEE(S) | Persimmon Technologies Corporation (Wakefield, Massachusetts) |
| INVENTOR(S) | Martin Hosek (Lowell, Massachusetts); Sripati Sah (Wakefield, Massachusetts); Jayaraman Krishnasamy (Boxborough, Massachusetts) |
| ABSTRACT | A soft magnetic material comprises a plurality of iron-containing particles and an insulating layer on the iron-containing particles, the insulating layer comprising an oxide. The soft magnetic material is an aggregate of permeable micro-domains separated by insulation boundaries. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 14/501603 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570578 | McCray et al. |
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| FUNDED BY |
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| APPLICANT(S) | Colorado School of Mines (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John McCray (Golden, Colorado); Skuyler Herzog (Golden, Colorado); Chris Higgins (Golden, Colorado) |
| ABSTRACT | Novel streamwater remediation systems and processes are presented. The disclosed systems involve design and placement of geometric volumes of porous media of variable hydraulic conductivity within the streambed to enhance hyporheic exchange (exchange of water from the stream or constructed urban waterway compartment to the porous media, or streambed, compartment). The disclosed systems may help improve water quality in various ways, for example through the removal of contaminants from water as it passes through the streambed. In some embodiments, contaminant removal is achieved by microbes and/or reactive geomedia incorporated into the streambed structures. By pairing hydrologic/flow structures with bacteria or reactive geomedia, diverse contaminants such as metals, nutrients, organics, pathogens, and more can be sorbed, deactivated, assimilated, transformed to harmless chemicals, and otherwise removed from the water. Because the structures are designed to return water to the stream after treatment, the stream water quality is improved by the structures. |
| FILED | Monday, May 18, 2015 |
| APPL NO | 14/715088 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Hydraulic Engineering E02B 5/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571460 | Sussman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Michael R. Sussman (Cross Plains, Wisconsin); J. Leon Shohet (Madison, Wisconsin); Faraz A. Choudhury (Madison, Wisconsin); Joshua M. Blatz (Monona, Wisconsin); Benjamin B. Minkoff (Madison, Wisconsin); Daniel I. Benjamin (Madison, Wisconsin) |
| ABSTRACT | This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule. |
| FILED | Friday, May 19, 2017 |
| APPL NO | 15/600352 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 2219/0809 (20130101) B01J 2219/0894 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 33/50 (20130101) Original (OR) Class G01N 33/487 (20130101) G01N 33/6848 (20130101) G01N 2333/765 (20130101) G01N 2333/90216 (20130101) G01N 2333/91215 (20130101) G01N 2440/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571606 | Altug et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hatice Altug (Watertown, Massachusetts); Ahmet Ali Yanik (Brighton, Massachusetts); Shyamsunder Erramilli (Quincy, Massachusetts); Ronen Adato (Boston, Massachusetts); Serap Aksu (Allston, Massachusetts); Min Huang (Boston, Massachusetts); Alp Artar (Brighton, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Hatice Altug (Watertown, Massachusetts); Ahmet Ali Yanik (Brighton, Massachusetts); Shyamsunder Erramilli (Quincy, Massachusetts); Ronen Adato (Boston, Massachusetts); Serap Aksu (Allston, Massachusetts); Min Huang (Boston, Massachusetts); Alp Artar (Brighton, Massachusetts) |
| ABSTRACT | The present invention generally relates to nanoantenna arrays and fabrication methods of said nanoantenna arrays. In particular, one aspect relates to nanoantenna arrays including nanostructures of predefined shapes in predefined patterns, which results in collective excitement of surface plasmons. The nanoantenna arrays can be used for spectroscopy and nanospectroscopy. Another aspects of the present invention relate to a method of high-throughput fabrication of nanoantenna arrays includes fabricating a reusable nanostencil for nanostensil lithography (NSL) which provides a mask to deposit materials onto virtually any support, such as flexible and thin-film stretchable supports. The nanostencil lithography methods enable high quality, high-throughput fabrication of nanostructures on conducting, non-conducting and magnetic supports. The nanostencil can be prepared by etching nanoapertures of predefined patterns into a waffer or ceramic membrane. In some embodiments, a nanoantenna array includes plasmonic nanostructures or non-plasmonic nanostructures. |
| FILED | Friday, October 22, 2010 |
| APPL NO | 13/509545 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 20/00 (20130101) B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 21/658 (20130101) Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/932 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571642 | Cohen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas) |
| INVENTOR(S) | Adam Cohen (Dallas, Texas); Paul Samuel Krueger (Plano, Texas); Matt Saari (Dallas, Texas); Edmond Richer (Richardson, Texas); Bryan Cox (Marion, Arkansas); Bin Xia (Dallas, Texas); Collin Gabriel Clay (Houston, Texas) |
| ABSTRACT | An apparatus for segmenting and feeding a fiber includes at least one capillary having a lumen therethrough configured to deliver a fiber segment. An advancing advances a fiber through the capillary. Tensioning means applies tension to the fiber to induce it to break. Damaging means locally damages the fiber. |
| FILED | Tuesday, February 19, 2019 |
| APPL NO | 16/279600 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/0056 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 64/209 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201) Optical Elements, Systems, or Apparatus G02B 6/4463 (20130101) Original (OR) Class Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/022 (20130101) H01R 4/024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571673 | Lin et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Lih-Yuan Lin (Seattle, Washington); Ethan G. Keeler (Seattle, Washington) |
| ABSTRACT | Devices and techniques for a particle positioning device are generally described. In some examples, a fluid may be introduced to a channel formed on a first surface of a substrate. In various examples, the channel may comprise a periodic dielectric structure etched in a first surface of the substrate and a channel wall material. In some examples, a laser beam may be directed through the channel wall material to the periodic dielectric structure. In various further examples, the laser beam may be reflected from the periodic dielectric structure into an interior region of the channel to form a focal enhancement region of the laser beam in the interior region of the channel adjacent to the periodic dielectric structure. In various examples, a force may be exerted on a particle suspended in the fluid with an electric field gradient generated by the focal enhancement region of the laser beam. |
| FILED | Monday, April 17, 2017 |
| APPL NO | 15/488806 |
| ART UNIT | 1799 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2015/1006 (20130101) Optical Elements, Systems, or Apparatus G02B 21/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572801 | Mars et al. |
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| FUNDED BY |
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| APPLICANT(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Jason Mars (Ann Arbor, Michigan); Lingjia Tang (Ann Arbor, Michigan); Michael Laurenzano (Ann Arbor, Michigan); Johann Hauswald (Ann Arbor, Michigan); Parker Hill (Ann Arbor, Michigan) |
| ABSTRACT | Systems and methods for implementing an artificially intelligent virtual assistant includes collecting a user query; using a competency classification machine learning model to generate a competency label for the user query; using a slot identification machine learning model to segment the text of the query and label each of the slots of the query; generating a slot value for each of the slots of the query; generating a handler for each of the slot values; and using the slot values to: identify an external data source relevant to the user query, fetch user data from the external data source, and apply one or more operations to the query to generate response data; and using the response data, to generate a response to the user query. |
| FILED | Wednesday, November 22, 2017 |
| APPL NO | 15/821010 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 16/35 (20190101) G06F 16/3329 (20190101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572814 | Friesen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Mark Friesen (Middleton, Wisconsin); Mark Eriksson (Madison, Wisconsin); Susan Coppersmith (Madison, Wisconsin) |
| ABSTRACT | A quantum computing system and method for performing quantum computation is provided. In some aspects, the system includes at least one charge qubit comprising a quantum dot assembly prepared with a symmetric charge distribution, wherein the symmetric charge distribution is configured to reduce a coupling between the charge qubit and a charge noise source. The system also includes a controller for controlling the at least one charge qubit to perform a quantum computation. The system further includes an output for providing a report generated using information obtained from the quantum computation performed. |
| FILED | Friday, January 15, 2016 |
| APPL NO | 14/996918 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 15/82 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
10573768 — Physical forms of MXene materials exhibiting novel electrical and optical characteristics
| US 10573768 | Ghidiu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Michael J. Ghidiu (Bridgeton, New Jersey); Michel W. Barsoum (Moorestown, New Jersey); Yury Gogotsi (Warminster, Pennsylvania); Aaron Thomas Fafarman (Philadelphia, Pennsylvania); Andrew DeVries Dillon (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention(s) is directed to novel conductive Mn+1Xn(Ts) compositions exhibiting high volumetric capacitances, and methods of making the same. The present invention(s) is also directed to novel conductive Mn+1Xn(Ts) compositions, methods of preparing transparent conductors using these materials, and products derived from these methods. |
| FILED | Wednesday, September 23, 2015 |
| APPL NO | 15/513740 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/58 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/022466 (20130101) Original (OR) Class H01L 33/42 (20130101) H01L 51/5203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573884 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Se-Hee Lee (Superior, Colorado); Daniela Molina Piper (Boulder, Colorado); Tyler Evans (Boulder, Colorado) |
| ASSIGNEE(S) | Regents Of The University Of Colorado, A Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Se-Hee Lee (Superior, Colorado); Daniela Molina Piper (Boulder, Colorado); Tyler Evans (Boulder, Colorado) |
| ABSTRACT | Various embodiments of the present disclosure describe energy storage devices. In one example, an energy storage device includes an anode having a plurality of active material particles, a cathode having a transition metal oxide material, and an electrolyte including a room temperature ionic liquid to couple the anode to the cathode. Each of the plurality of anode active material particles have a particle size of between about one micrometer and about fifty micrometers. One or more of the plurality of anode active material particles are enclosed by and in contact with a membrane coating permeable to lithium ions. |
| FILED | Thursday, January 28, 2016 |
| APPL NO | 15/544836 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 4/134 (20130101) Original (OR) Class H01M 4/366 (20130101) H01M 4/386 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 10/44 (20130101) H01M 10/448 (20130101) H01M 10/0525 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2004/027 (20130101) H01M 2300/0045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574028 | Wei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rhode Island Council on Postsecondary Education (Warwick, Rhode Island) |
| ASSIGNEE(S) | Rhode Island Council on Postsecondary Education (Warwick, Rhode Island) |
| INVENTOR(S) | Tao Wei (West Kingston, Rhode Island); Zheyi Yao (Kingston, Rhode Island); Yan Sun (Kingston, Rhode Island) |
| ABSTRACT | The present disclosure provides a unique digitally integrated, self-trained pre-distortion curve generation method and apparatus for semiconductor lasers (SCLs) to generate linearly swept optical signals that are applicable to a wide range of sweep velocities and semiconductor laser types. The method requires no prior knowledge of the frequency response of the laser and is highly accurate. |
| FILED | Tuesday, February 26, 2019 |
| APPL NO | 16/285738 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/042 (20130101) H01S 5/0617 (20130101) H01S 5/0683 (20130101) H01S 5/06223 (20130101) Original (OR) Class H01S 5/06817 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574154 | Qiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Wei Qiao (Lincoln, Nebraska); Fa Chen (Lincoln, Nebraska); Liyan Qu (Lincoln, Nebraska) |
| ABSTRACT | A scalable universal space vector pulse-width modulation (SVPWM) scheme for multilevel inverters is disclosed. In the disclosed SVPWM scheme, the modulation triangle is quickly identified based on a coordinate transformation from an α-β coordinate system to a 120° oblique coordinate system. Then, the duty cycles and switching states of the three vertices of the modulation triangle are determined by simple algebraic computations. In a switching period, any vertex of the modulation triangle can be flexibly selected as the start point to optimize the switching sequence with flexibly adjustable duty cycle(s) for the redundant switching state(s) according to specific applications. |
| FILED | Friday, September 01, 2017 |
| APPL NO | 15/694135 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/08 (20130101) H02M 7/5395 (20130101) Original (OR) Class H02M 2001/0054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574298 | Pierson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Timothy J. Pierson (Hanover, New Hampshire); Xiaohui Liang (West Lebanon, New Hampshire); Ronald Peterson (Brattleboro, Vermont); David Kotz (Lyme, New Hampshire) |
| ABSTRACT | Apparatus and method securely transfer first data from a source device to a target device. A wireless signal having (a) a higher speed channel conveying second data and (b) a lower speed channel conveying the first data is transmitted. The lower speed channel is formed by selectively transmitting the wireless signal from one of a first and second antennae of the source device based upon the first data. The first and second antenna are positioned a fixed distance apart and the target device uses a received signal strength indication (RSSI) of the first signal to decode the lower speed channel and receive the first data. |
| FILED | Thursday, June 23, 2016 |
| APPL NO | 15/739122 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 5/0031 (20130101) Original (OR) Class H04B 17/318 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574313 | Shepard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Skylark Wireless, LLC (Houston, Texas) |
| ASSIGNEE(S) | Skylark WL Holdings, LLC (Houston, Texas) |
| INVENTOR(S) | Clayton Wells Shepard (Houston, Texas); Evan J. Everett (Houston, Texas); Ashutosh Sabharwal (Houston, Texas); Lin Zhong (Houston, Texas) |
| ABSTRACT | Technique for full-duplex transmission in many-antenna multi-user (MU) multiple-input multiple-output (MIMO) systems is presented in this disclosure. An estimate of a self-interference channel between a plurality of transmit antennas and a plurality of receive antennas is first obtained. A precoder for self-interference reduction is generated based on minimizing a self-interference power related to the self-interference channel that is present at the plurality of receive antennas. Transmission data are modified using the precoder by projecting the transmission data onto a defined number of singular vectors of the self-interference channel that correspond to the defined number of smallest singular values of the self-interference channel. Data are received in full-duplex mode via the plurality of receive antennas simultaneously with transmitting the modified transmission data. |
| FILED | Saturday, April 23, 2016 |
| APPL NO | 15/540129 |
| ART UNIT | 2477 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 7/0452 (20130101) H04B 7/0456 (20130101) Original (OR) Class H04B 7/0615 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574721 | Bazzi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Arizona Board of Regents for and on Behalf of Arizona State University (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Rida A. Bazzi (Scottsdale, Arizona); Mohsen Zohrevandi (Tempe, Arizona) |
| ABSTRACT | A system and method for securing access to sensitive content on the web is disclosed. The approach automates compartmentalization practices for accessing different kinds of content with different browser instances. The automation is transparent to the user and does not require any modification of how non-sensitive content is accessed. For sensitive content, a Fresh Browser Instance (FBI) is automatically created to access the content. In addition, the automatic FBI system may provide support for novice users with predefined sensitive content sites as well as for more experienced users who can define conflict of interest (COI) classes which allows content from sites in the same user-defined class to coexist in a browser instance. |
| FILED | Monday, December 08, 2014 |
| APPL NO | 14/563712 |
| ART UNIT | 2458 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 21/52 (20130101) G06F 21/6263 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10575277 | Luo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Zhihong Luo (Cambridge, Massachusetts); Qiping Zhang (Hong Kong, China Hong Kong); Nicholas Selby (Cambridge, Massachusetts); Yunfei Ma (Santa Clara, California); Manish Singh (Delhi, India); Fadel Adib (Cambridge, Massachusetts) |
| ABSTRACT | A wideband, radio-frequency localization system may estimate the one-dimensional, two-dimensional or three-dimensional position and trajectory of a static or moving object. These estimates may have a high spatial accuracy and low latency. The localization may be determined based on phase or amplitude of a wideband signal in each frequency band in a set of multiple frequency bands. The localization may be based on a single shot of measurements across a wide band of radio frequencies, without frequency hopping. The measurements of the wideband signal may be taken over time and over space at multiple receivers. The localization may be based on measurements taken while a backscatter node remains in a first reflective state or in a second reflective state, rather than when the backscatter node is transitioning between reflective states. In some cases, the localization achieves sub-centimeter spatial resolution in each of three spatial dimensions. |
| FILED | Tuesday, October 16, 2018 |
| APPL NO | 16/162085 |
| ART UNIT | 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0221 (20130101) G01S 5/0278 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0007 (20130101) H04L 27/265 (20130101) Wireless Communication Networks H04W 64/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10575331 | Grissa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Mohamed Grissa (Corvallis, Oregon); Attila Yavuz (Corvallis, Oregon); Bechir Hamdaoui (Corvallis, Oregon) |
| ABSTRACT | An apparatus is provided which comprises: logic to privately compare one or more received Order Preserving Encrypted (OPE) signal strength (RSS) values, from a plurality of secondary users (SUs), with a OPE threshold value; a transmitter to send the comparison result to a fusion center (FC); and a receiver to receive the OPE threshold value from the FC. |
| FILED | Thursday, February 22, 2018 |
| APPL NO | 15/902965 |
| ART UNIT | 2467 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 17/318 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/162 (20130101) Wireless Communication Networks H04W 12/02 (20130101) H04W 12/04 (20130101) H04W 16/14 (20130101) H04W 74/002 (20130101) H04W 74/0816 (20130101) Original (OR) Class H04W 88/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE47874 | Bazan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Guillermo C. Bazan (Santa Barbara, California); Brent S. Gaylord (San Diego, California); Shu Wang (Beijing, China PRC) |
| ABSTRACT | Methods, compositions and articles of manufacture for assaying a sample for a target polynucleotide are provided. A sample suspected of containing the target polynucleotide is contacted with a polycationic multichromophore and a sensor polynucleotide complementary to the target polynucleotide. The sensor polynucleotide comprises a signaling chromophore to receive energy from the excited multichromophore and increase emission in the presence of the target polynucleotide. The methods can be used in multiplex form. Kits comprising reagents for performing such methods are also provided. |
| FILED | Friday, March 23, 2018 |
| APPL NO | 15/934874 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6813 (20130101) C12Q 1/6818 (20130101) C12Q 1/6825 (20130101) C12Q 1/6834 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10569415 | Doggett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | William R. Doggett (Poquoson, Virginia); John T. Dorsey (Hampton, Virginia); Thomas C. Jones (Newport News, Virginia); Bruce D. King (Yorktown, Virginia) |
| ABSTRACT | A manipulator includes first and second link arms which are connected together by a hinge. A cable actuation and tensioning system is provided between the link arms and includes a spreader arm, a driven element attached to each link arm and a cable engaged with the respective driven element and attached to the spreader arm. At least one of the arms, or all of the arms, can telescope to shorten or lengthen the arm(s) by movement of the system. The spreader arm may also be configured to slide relative to the first and second link arms to change the position of the spreader arm relative to the first and second link arms. |
| FILED | Wednesday, August 31, 2016 |
| APPL NO | 15/253184 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/06 (20130101) B25J 9/1045 (20130101) Original (OR) Class B25J 18/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569849 | Stone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stone Aerospace, Inc. (Del Valle, Texas) |
| ASSIGNEE(S) | Stone Aerospace, Inc. (Del Valle, Texas) |
| INVENTOR(S) | William C. Stone (Del Valle, Texas); Evan Clark (Pasedena, California); Kristof Richmond (Miami, Florida); Jeremy Paulus (Santa Clara, California); Jason Kapit (Pocasset, Massachusetts); Mark Scully (Portland, Oregon); Peter Kimball (Palo Alto, California) |
| ABSTRACT | A system for automated rendezvous, docking, and capture of autonomous underwater vehicles at the conclusion of a mission comprising of comprised of a docking rod having lighted, pulsating (in both frequency and light intensity) series of LED light strips thereon, with the LEDs at a known spacing, and the autonomous underwater vehicle specially designed to detect and capture the docking rod and then be lifted structurally by a spherical end strop about which the vehicle can be pivoted and hoisted up (e.g., onto a ship). The method of recovery allows for very routine and reliable automated recovery of an unmanned underwater asset. |
| FILED | Monday, January 22, 2018 |
| APPL NO | 15/876507 |
| ART UNIT | 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 2027/165 (20130101) B63B 2231/76 (20130101) B63B 2702/12 (20130101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) Original (OR) Class B63G 2008/004 (20130101) B63G 2008/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10569939 | Younse |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Paulo J. Younse (Pasadena, California) |
| ABSTRACT | An axially sealing plug may not require modification of a hole being sealed in a tube or pipe. The plug may only require an axial load for activation (not torque), work independently of temperature, require no explosives, and be lightweight and compact. The plug may include a housing or a seal cup that includes at least one tooth on an outer surface and a ramp on an inner surface. The plug may also include a ferrule including a beveled, curved, or chamfered lower end. The ferrule is configured to be inserted inside the housing or seal cup. |
| FILED | Monday, March 21, 2016 |
| APPL NO | 15/075542 |
| ART UNIT | 3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 45/30 (20130101) Original (OR) Class B65D 53/02 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 55/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571419 | Lenagh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rosemount Aerospace Inc. (Burnsville, Minnesota) |
| ASSIGNEE(S) | Rosemount Aerospace Inc. (Burnsville, Minnesota) |
| INVENTOR(S) | Thomas Lenagh (Farmington, Minnesota); Rudy Pitera (Woodbury, Minnesota); Tomas Lorincz (Savage, Minnesota) |
| ABSTRACT | A conductivity cell includes a cylindrical flow tube holder having a closed first end and an open second end, a first end fitting positioned on the first end of the flow tube holder, a second end fitting positioned on the second end of the flow tube holder, a flow tube positioned within the flow tube holder, an end cap positioned in the open second end of the flow tube holder and adjacent the flow tube and the second end fitting, a plurality of electrodes positioned in the flow tube, a plurality of o-rings positioned on the electrodes, and a flow through hole extending from the first end fitting through the flow tube holder, the flow tube, and the end cap to the second end fitting. The plurality of electrodes are press-fit into the flow tube. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 15/604231 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/07 (20130101) G01N 27/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573344 | Merritt |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S.A., as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Scott A. Merritt (McLean, Virginia) |
| ABSTRACT | The present invention relates to a slot clock generator for high data rate pulse position modulation (PPM), including: a set of clocks with predetermined frequencies that are mutually prime in pairs, the set of clocks which synthesizes and accumulates changes in clock states at a rate corresponding to a slot rate that is greater than a slot rate of any single clock in the set. |
| FILED | Tuesday, June 20, 2017 |
| APPL NO | 15/627658 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 20/16 (20130101) Original (OR) Class Demodulation or Transference of Modulation From One Carrier to Another H03D 3/24 (20130101) Pulse Technique H03K 3/02 (20130101) Transmission H04B 1/69 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573458 | Hull et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | John R. Hull (Sammamish, Washington); Vyacheslav Khozikov (Bellevue, Washington); Shengyi Liu (Sammamish, Washington); Eugene V. Solodovnik (Lake Stevens, Washington); John Dalton Williams (Decatur, Alabama) |
| ABSTRACT | Provided is a low-weight, high-efficiency inductor design for use with or in electrical power equipment, such as inverters. A toroidal power inductor includes a support structure comprising an outer shell, an inner shell, and one or more coolant channels formed therebetween, a plurality of conductors wrapped around and supported by an exterior surface of the outer shell, and an interior cavity substantially enclosed by the inner shell of the toroidal support structure. The plurality of conductors are configured to provide an inductance for the toroidal power inductor, and the one or more coolant channels are distributed beneath the exterior surface of the outer shell to cool the plurality of conductors. An air-core power inductor may implement the conductors using high-temperature superconducting (HTS) tapes cooled by cryogenic fluid flowing within the coolant channels. |
| FILED | Wednesday, October 05, 2016 |
| APPL NO | 15/286448 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 6/04 (20130101) H01F 6/065 (20130101) H01F 37/005 (20130101) H01F 41/048 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573464 | Rolin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Terry D. Rolin (Elkmont, Alabama); Ian K. Small (Madison, Alabama); Curtis W. Hill (Meridianville, Alabama) |
| ABSTRACT | An energy storage capacitor has a solid dielectric sandwiched between two electrodes. The solid dielectric is a lanthanum-doped barium titanate-based ceramic material. A dopant is selected from the group consisting of lanthanum hydroxide and lanthanum oxide, and a co-dopant is an alkali hydroxide selected from the group consisting of potassium hydroxide, sodium hydroxide, rubidium hydroxide, and lithium hydroxide. |
| FILED | Tuesday, October 23, 2018 |
| APPL NO | 16/167861 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/4682 (20130101) C04B 35/6262 (20130101) C04B 2235/36 (20130101) C04B 2235/96 (20130101) C04B 2235/656 (20130101) C04B 2235/3201 (20130101) C04B 2235/3203 (20130101) C04B 2235/3215 (20130101) C04B 2235/3227 (20130101) C04B 2235/3236 (20130101) C04B 2235/5436 (20130101) C04B 2235/5445 (20130101) C04B 2235/5454 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/005 (20130101) H01G 4/30 (20130101) Original (OR) Class H01G 4/38 (20130101) H01G 4/224 (20130101) H01G 4/1227 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/185 (20130101) H01M 8/0217 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573465 | Rolin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Terry D. Rolin (Elkmont, Alabama); Ian K. Small (Madison, Alabama); Curtis W. Hill (Meridianville, Alabama) |
| ABSTRACT | A solid dielectric for an energy storage capacitor is a lanthanum-doped barium titanate-based ceramic material. A dopant is selected from the group consisting of lanthanum hydroxide and lanthanum oxide, and a co-dopant is an alkali hydroxide selected from the group consisting of potassium hydroxide, sodium hydroxide, rubidium hydroxide, and lithium hydroxide. |
| FILED | Tuesday, October 23, 2018 |
| APPL NO | 16/167885 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/4682 (20130101) C04B 35/6262 (20130101) C04B 2235/36 (20130101) C04B 2235/96 (20130101) C04B 2235/656 (20130101) C04B 2235/3201 (20130101) C04B 2235/3203 (20130101) C04B 2235/3215 (20130101) C04B 2235/3227 (20130101) C04B 2235/3236 (20130101) C04B 2235/5436 (20130101) C04B 2235/5445 (20130101) C04B 2235/5454 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/005 (20130101) H01G 4/30 (20130101) Original (OR) Class H01G 4/38 (20130101) H01G 4/224 (20130101) H01G 4/1227 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/185 (20130101) H01M 8/0217 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10571520 | Maliuk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | Internatioanl Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dzmitry S. Maliuk (Addison, Texas); Franco Stellari (Waldwick, New Jersey); Alan J. Weger (Mohegan Lake, New York); Peilin Song (Lagrangeville, New York) |
| ABSTRACT | A scan chain latch circuit, a method of operating a latch circuit in a scan chain, and a computer-readable medium having stored thereon a data structure defining a scan chain latch circuit for instantiation on a semiconductor die are disclosed. In an embodiment, the scan chain latch circuit comprises a first latch for holding one data value, a second latch for holding another data value, and a multiplexor. The one data value is applied to a first data input of the multiplexor and the another data value is applied to a second data input of the multiplexor. An alternating clock signal is applied to a select input of the multiplexor to control the output of the multiplexor, wherein the output of the multiplexor toggles between the two data values held in the two latches at a defined frequency. |
| FILED | Tuesday, May 09, 2017 |
| APPL NO | 15/590617 |
| ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3177 (20130101) Original (OR) Class G01R 31/31723 (20130101) G01R 31/31727 (20130101) G01R 31/318516 (20130101) G01R 31/318519 (20130101) G01R 31/318541 (20130101) G01R 31/318572 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572376 | Fleming, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kermin Elliott Fleming, Jr. (Hudson, Massachusetts); Simon C. Steely, Jr. (Hudson, New Hampshire); Kent D. Glossop (Nashua, New Hampshire) |
| ABSTRACT | An integrated circuit includes a memory interface, coupled to a memory to store data corresponding to instructions, and an operations queue to buffer memory operations corresponding to the instructions. The integrated circuit may include acceleration hardware to execute a sub-program corresponding to the instructions. A set of input queues may include an address queue to receive, from the acceleration hardware, an address of the memory associated with a second memory operation of the memory operations, and a dependency queue to receive, from the acceleration hardware, a dependency token associated with the address. The dependency token indicates a dependency on data generated by a first memory operation of the memory operations. A scheduler circuit may schedule issuance of the second memory operation to the memory in response to the dependency queue receiving the dependency token and the address queue receiving the address. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/396038 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0619 (20130101) G06F 3/0659 (20130101) G06F 3/0685 (20130101) G06F 9/3838 (20130101) G06F 9/30043 (20130101) G06F 12/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572819 | Klinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Tamir Klinger (Brooklyn, New York); Chandrasekhara K. Reddy (Kinnelon, New Jersey); Ashish Sabharwal (White Plains, New York); Horst C. Samulowitz (White Plains, New York); Gerald J. Tesauro (Croton-on-Hudson, New York); Deepak S. Turaga (Elmsford, New York) |
| ABSTRACT | A system, method, and computer program product for automatically selecting from a plurality of analytic algorithms a best performing analytic algorithm to apply to a dataset is provided. The automatically selecting from the plurality of analytic algorithms the best performing analytic algorithm to apply to the dataset enables a training a plurality of analytic algorithms on a plurality of subsets of the dataset. Then, a corresponding prediction accuracy trend is estimated across the subsets for each of the plurality of analytic algorithms to produce a plurality of accuracy trends. Next, the best performing analytic algorithm is selected and outputted from the plurality of analytic algorithms based on the corresponding prediction accuracy trend with a highest value from the plurality of accuracy trends. |
| FILED | Wednesday, July 29, 2015 |
| APPL NO | 14/812344 |
| ART UNIT | 2122 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) G06N 20/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572968 | Riabov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Anton V. Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (Port Chester, New York); Octavian Udrea (Onissing, New York) |
| ABSTRACT | Techniques for translating graphical representations of domain knowledge are provided. In one example, a computer-implemented method comprises receiving, by a device operatively coupled to a processor, a graphical representation of domain knowledge. The graphical representation comprises information indicative of a central concept and at least one chain of events associated with the central concept. The computer-implemented method further comprises translating, by the device, the graphical representation into an artificial intelligence planning problem. The artificial intelligence planning problem is expressed in an artificial intelligence description language. The translating comprises parsing the graphical representation into groupings of terms. A first grouping of terms of the grouping of terms comprises an event from the at least one chain of events and a second grouping of terms of the grouping of terms comprises the information indicative of the central concept. The computer-implemented method also comprises validating, by the device, the artificial intelligence planning problem. |
| FILED | Thursday, March 07, 2019 |
| APPL NO | 16/295731 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 16/532 (20190101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 5/022 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 1/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10570494 | Hosek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Persimmon Technologies, Corp. (Wakefield, Massachusetts) |
| ASSIGNEE(S) | Persimmon Technologies Corporation (Wakefield, Massachusetts) |
| INVENTOR(S) | Martin Hosek (Lowell, Massachusetts); Sripati Sah (Wakefield, Massachusetts); Jayaraman Krishnasamy (Boxborough, Massachusetts) |
| ABSTRACT | A soft magnetic material comprises a plurality of iron-containing particles and an insulating layer on the iron-containing particles, the insulating layer comprising an oxide. The soft magnetic material is an aggregate of permeable micro-domains separated by insulation boundaries. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 14/501603 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10571505 | Keller, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NOKOMIS, INC. (Charleroi, Pennsylvania) |
| ASSIGNEE(S) | NOKOMIS, INC. (Charleroi, Pennsylvania) |
| INVENTOR(S) | Walter John Keller, III (Bridgeville, Pennsylvania); Andrew Richard Portune (Oakdale, Pennsylvania); Todd Eric Chornenky (Carmichaels, Pennsylvania); William Anthony Davis (Perrysburg, Ohio) |
| ABSTRACT | An apparatus for detecting a condition or authenticity of one or more electronic devices includes an enclosure having an antenna integrated therewithin, a fixture mounted within a hollow interior of the enclosure, the fixture being configured to receive the one or more electronic devices and connect one or more signals to each of the one or more electronic devices and a sensor and controller assembly connected to the antenna and configured to process a signature of an emission of a radiofrequency (RF) energy from of one or more electronic devices having the one or more signals connected thereto. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/847819 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/002 (20130101) Original (OR) Class Electric Digital Data Processing G06F 21/73 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10572801 | Mars et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Jason Mars (Ann Arbor, Michigan); Lingjia Tang (Ann Arbor, Michigan); Michael Laurenzano (Ann Arbor, Michigan); Johann Hauswald (Ann Arbor, Michigan); Parker Hill (Ann Arbor, Michigan) |
| ABSTRACT | Systems and methods for implementing an artificially intelligent virtual assistant includes collecting a user query; using a competency classification machine learning model to generate a competency label for the user query; using a slot identification machine learning model to segment the text of the query and label each of the slots of the query; generating a slot value for each of the slots of the query; generating a handler for each of the slot values; and using the slot values to: identify an external data source relevant to the user query, fetch user data from the external data source, and apply one or more operations to the query to generate response data; and using the response data, to generate a response to the user query. |
| FILED | Wednesday, November 22, 2017 |
| APPL NO | 15/821010 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 16/35 (20190101) G06F 16/3329 (20190101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574277 | Terry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John David Terry (Annandale, Virginia); Anthony Reid (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John David Terry (Annandale, Virginia); Anthony Reid (Tucson, Arizona) |
| ABSTRACT | The present invention teaches a system and method for improved signal recovery for range and coverage extension in a heterogeneous cooperative network of digital chaos transmissions with OFDM component signal transmission. The invention improves upon the state of art in side channel information from the transmit side containing information on the clipped amplitude. In-band transmission of the side information is achieved by exploiting the sparsity of the resulting clip amplitude position with improved levels of compression over the prior art using Gabor Transform Multiple Symbol Encoding transmitter. The information rate of the clipped amplitude is sub-Nyquist relative to the original OFDM component signal transmission, which allows very low power spreading by a cooperative digital chaos sequences at a transmit side and recovery of the clipped amplitude at a receive side. Further, an improved noise resistance side channel performance is achieved by decoding Gabor Transform symbols for symbol recovery. |
| FILED | Monday, February 20, 2017 |
| APPL NO | 15/436957 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/69 (20130101) H04B 1/0475 (20130101) Original (OR) Class H04B 1/7136 (20130101) H04B 7/00 (20130101) H04B 7/0413 (20130101) H04B 2201/71323 (20130101) Multiplex Communication H04J 13/0018 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/08 (20130101) H04L 1/1621 (20130101) H04L 27/001 (20130101) H04L 27/2601 (20130101) H04L 27/2614 (20130101) H04L 27/2623 (20130101) H04L 69/22 (20130101) Wireless Communication Networks H04W 4/70 (20180201) H04W 12/04 (20130101) H04W 12/06 (20130101) H04W 16/26 (20130101) H04W 40/244 (20130101) H04W 48/10 (20130101) H04W 52/244 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 70/21 (20180101) Y02D 70/22 (20180101) Y02D 70/23 (20180101) Y02D 70/40 (20180101) Y02D 70/44 (20180101) Y02D 70/142 (20180101) Y02D 70/144 (20180101) Y02D 70/444 (20180101) Y02D 70/1262 (20180101) Y02D 70/1264 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10568320 | Vander Meer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Foresight Science and Technology, Inc. (Hopkinton, Massachusetts) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Foresight Science and Technology Inc. (Hopkinton, Massachusetts) |
| INVENTOR(S) | Robert K. Vander Meer (Newberry, Florida); Satya P. Chinta (Gainesville, Florida) |
| ABSTRACT | The present invention provides novel compositions and methods for using the insect neuromodulator tyramine and/or one or more derivatives thereof delivered to insect populations to control certain aspects of such populations. The amount of tyramine and/or one or more derivatives thereof delivered on a per insect basis is significantly greater than a naturally-occurring amount of tyramine normally found in insects and causes deleterious effects including mortality of certain insect life forms and disruption of the reproductive capacity of others in the population. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 15/908105 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/2011 (20130101) A01M 2200/011 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/006 (20130101) A01N 33/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10568831 | Mendenhall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Heather N. Mendenhall (Madison, Wisconsin); Richard W. Hartel (Madison, Wisconsin); JoAnne Robbins (Madison, Wisconsin); Jacqueline A. Hind (Madison, Wisconsin); Zata M. Vickers (St. Paul, Minnesota) |
| ABSTRACT | An edible composition of matter having an apparent viscosity of from about 150 cP to about 2000 cP at about 30 s−1; a yield stress of from 0 Pa to about 20 Pa at 1 s−1; and a flow index of from about 0.2 to about 0.6. The composition may include an imaging agent. The compositions are useful for providing sustenance to dysphagic subjects and for evalualuating dysphagia. |
| FILED | Thursday, March 14, 2013 |
| APPL NO | 13/804781 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 2/38 (20130101) A23L 33/10 (20160801) A23L 33/30 (20160801) A23L 33/40 (20160801) Diagnosis; Surgery; Identification A61B 5/038 (20130101) A61B 5/4205 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) Original (OR) Class A61K 9/0056 (20130101) A61K 9/0095 (20130101) A61K 47/00 (20130101) A61K 49/0404 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10570172 | Hnasko |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert M. Hnasko (Port Costa, California) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Robert M. Hnasko (Port Costa, California) |
| ABSTRACT | Self assembling peptides in combination with infectious and non-infectious proteins as inhibitors and diagnostic tools in transmissible spongiform encephalopathies and amyloid producing neuorodegenerative diseases are described herein. |
| FILED | Wednesday, September 30, 2009 |
| APPL NO | 12/571228 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/34 (20130101) A61K 38/03 (20130101) Peptides C07K 4/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 10574817 | Strom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | RESEARCH TRIANGLE INSTITUTE (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Kevin Jay Strom (Research Triangle Park, North Carolina); Mark William Pope (Research Triangle Park, North Carolina); Maurice A Martin (Research Triangle Park, North Carolina); Christopher Michael Griggs (Research Triangle Park, North Carolina); James Illiad Rineer (Research Triangle Park, North Carolina); Crystal Majors Daye (Research Triangle Park, North Carolina) |
| ABSTRACT | Computer-implemented methods and computer-readable media are disclosed for processing call-for-service data to facilitate queries and reports to enhance usefulness of call-for-service data. In one embodiment, a computer-implemented method performable by a computer system includes receiving at a computer system data for a plurality of calls-for-service. Individual data for an individual call-for-service includes one or more fields storing information relating to the call-for-service. Based on the information stored within the one or more fields of the individual data, one or more supplemental classifiers are automatically identified. The one or more supplemental classifiers are associated with the individual data. The one or more supplemental classifiers associated with the individual data enable the individual call-for-service to be identified when the one or more supplemental classifiers match one or more specified criteria. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/775683 |
| ART UNIT | 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Telephonic Communication H04M 3/5116 (20130101) Original (OR) Class H04M 3/5191 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10571360 | Lajnef et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Nizar Lajnef (Lansing, Michigan); Mohamed Rhimi (Elmouroujz, Turkey) |
| ABSTRACT | A computer-implemented method is provided for estimating the remaining life of a structure being monitored by a sensor. The method includes: receiving data from a sensor, where the data is indicative of strain experienced by a structure and is reported as a plurality of cumulative distribution functions; extracting a probability density function from the data received from the sensor; computing a damage index for the structure from parameters of the probability density function, where the damage index is indicative of damage to the structure accumulated over time; and estimating a remaining life of the structure using the damage index. |
| FILED | Tuesday, April 17, 2018 |
| APPL NO | 15/955105 |
| ART UNIT | 2854 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/16 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 5/0008 (20130101) G01M 5/0016 (20130101) G01M 5/0033 (20130101) G01M 5/0041 (20130101) Original (OR) Class G01M 15/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10571715 | Rizzo, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MASSACHUSETTS EYE and EAR INFIRMARY (Boston, Massachusetts); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts); The United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Joseph F. Rizzo, III (Newton, Massachusetts); Attila Priplata (Arlington, Massachusetts); Minnan Xu (Cambridge, Massachusetts); Conrad Wall, III (Boston, Massachusetts) |
| ABSTRACT | The disclosure features visual assistive devices that include a detection apparatus configured to receive information about an environment surrounding a user of the visual assistive device, a communication apparatus configured to transmit information to the user, and an electronic processor coupled to the detection apparatus and the communication apparatus, and configured to: receive information about an activity of the user; filter the information about the environment surrounding the user based on the activity of the user; assign a priority rank to each element of the filtered information based on the activity of the user; and transmit at least some of the elements of the filtered information, according to the assigned priority ranks, to the user using the communication apparatus. |
| FILED | Monday, November 05, 2012 |
| APPL NO | 14/356071 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/08 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/061 (20130101) A61H 2201/165 (20130101) A61H 2201/0184 (20130101) A61H 2201/501 (20130101) A61H 2201/503 (20130101) A61H 2201/5007 (20130101) A61H 2201/5048 (20130101) A61H 2201/5069 (20130101) A61H 2201/5079 (20130101) A61H 2201/5084 (20130101) A61H 2201/5092 (20130101) A61H 2201/5097 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36046 (20130101) Optical Elements, Systems, or Apparatus G02B 27/646 (20130101) Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 5/001 (20130101) Original (OR) Class G02C 11/10 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 2205/0007 (20130101) G03B 2217/005 (20130101) Pictorial Communication, e.g Television H04N 5/23258 (20130101) H04N 5/23261 (20130101) H04N 5/23267 (20130101) H04N 5/23287 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 10568992 | Lipke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Auburn University (Auburn, Alabama) |
| ASSIGNEE(S) | Auburn University (Auburn, Alabama) |
| INVENTOR(S) | Elizabeth A. Lipke (Auburn, Alabama); Wen Jun Seeto (Auburn, Alabama) |
| ABSTRACT | The present invention relates to the production of endothelialized matrices and materials from immature endothelial cells using substrates to which particular peptides have been grafted. The resultant substrates can be used to capture and support immature endothelial cells. Further, the methods and compositions of the present invention provide viable cell delivery platforms that allow for production and provision of endothelialized medical devices and implants, including vascular grafts, stents, shunts, and valves, endothelialized surfaces and channels for in vitro testing devices, including microfluidic chips, and materials that support vascularization such as for use in engineered tissues. The present invention includes novel methods required for the successful production of cellularized substrates, systems and components used for the same, and methods of using the resultant cell and tissue compositions. |
| FILED | Thursday, April 14, 2016 |
| APPL NO | 15/099582 |
| ART UNIT | 1676 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/227 (20130101) A61L 27/3683 (20130101) A61L 31/005 (20130101) A61L 31/16 (20130101) Original (OR) Class A61L 31/047 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 2533/30 (20130101) C12N 2533/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10572705 | Garey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Ronald E. Garey (Mitchellville, Maryland); Suzanne N. Dunn (Selma, North Carolina) |
| ABSTRACT | A system for providing document authenticity, securing, and tracing includes a mark, an invisible code and a serial number. A user desiring to create a secure, verifiable document can receive one or more codes or indicia to put on the physical document. |
| FILED | Friday, August 24, 2018 |
| APPL NO | 16/111748 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Electric Digital Data Processing G06F 16/93 (20190101) G06F 16/245 (20190101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) Original (OR) Class Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing G07D 7/005 (20170501) G07D 7/0043 (20170501) G07D 7/0047 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10572597 | Ackermann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Christopher F. Ackermann (Fairfax, Virginia); Charles E. Beller (Baltimore, Maryland); Stephen A. Boxwell (Franklin, Ohio); Edward G. Katz (Washington, District of Columbia); Kristen M. Summers (Takoma Park, Maryland) |
| ABSTRACT | According to one embodiment, a method, computer system, and computer program product for acronym resolution is provided. The present invention may include receiving documents; identifying explicit expansions within the documents; receiving an input from a user; retrieving passages relevant to the received input from the documents; for each acronym within the one or more relevant passages, determining whether the acronym corresponds with explicit expansions within the relevant passages; for each of the acronyms that do not correspond with explicit expansions, determining whether the acronym corresponds with implicit expansions within the relevant passages; and for each of the acronyms that do not correspond with implicit expansions, determining whether the acronym corresponds with acronyms within a universal acronym list, and transmitting the one or more resolved acronyms to a question answering system. |
| FILED | Thursday, November 30, 2017 |
| APPL NO | 15/826834 |
| ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 17/276 (20130101) G06F 17/2705 (20130101) G06F 17/2765 (20130101) G06F 17/2785 (20130101) Original (OR) Class G06F 17/2795 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10573775 | Holmes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James A. Holmes (Fayetteville, Arkansas); Matthew Francis (Elkins, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James A. Holmes (Fayetteville, Arkansas); Matthew Francis (Elkins, Arkansas) |
| ABSTRACT | A bipolar complementary metal oxide semiconductor three transistor pixel with P-type metal-oxide-semiconductor base discharge and N-type metal-oxide-semiconductor emitter blocking. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/044882 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) G01J 1/429 (20130101) G01J 2001/4473 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14614 (20130101) H01L 27/14681 (20130101) H01L 31/028 (20130101) H01L 31/1105 (20130101) Original (OR) Class H01L 31/02019 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10574251 | Stoutimore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micah John Atman Stoutimore (Kensington, Maryland); Timothy A. Manning (Silver Spring, Maryland); Mark E. Nowakowski (Millersville, Maryland); Alexander Marakov (Columbia, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Micah John Atman Stoutimore (Kensington, Maryland); Timothy A. Manning (Silver Spring, Maryland); Mark E. Nowakowski (Millersville, Maryland); Alexander Marakov (Columbia, Maryland) |
| ABSTRACT | One example includes a Josephson analog-to-digital converter (ADC) system. The system includes a control line inductively coupled to an input signal line on which an input analog signal is provided. The input signal line can be inductively coupled to the control line to propagate an induced input current that is based on the input analog signal on the control line. The system also includes at least one Josephson transmission line (JTL) stage that is biased via a DC bias current and is configured to generate an output pulse in response to the induced input current and the DC bias current exceeding a predetermined threshold current associated with the at least one JTL stage. |
| FILED | Friday, March 01, 2019 |
| APPL NO | 16/290373 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 19/195 (20130101) Coding; Decoding; Code Conversion in General H03M 1/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 25, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200225.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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