FedInvent™ Patents

Patent Details for Tuesday, March 03, 2020

This page was updated on Monday, March 27, 2023 at 06:02 AM GMT

Department of Health and Human Services (HHS)

10575515 — Methods and compositions for preserving tissues and organs

US 10575515	Yarmush et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Martin L. Yarmush (Newton, Massachusetts); Mehmet Toner (Wellesley, Massachusetts); Maria-Louisa Izamis (Boston, Massachusetts); Timothy Antonie Berendsen (Melrose, Massachusetts); Robert Marius Bieganski (Cambridge, Massachusetts); Osman Berk Usta (Watertown, Massachusetts); Basak Elif Uygun (Cambridge, Massachusetts); Mustafa Korkut Uygun (Cambridge, Massachusetts); Sinem Perk (Chicago, Illinois)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Martin L. Yarmush (Newton, Massachusetts); Mehmet Toner (Wellesley, Massachusetts); Maria-Louisa Izamis (Boston, Massachusetts); Timothy Antonie Berendsen (Melrose, Massachusetts); Robert Marius Bieganski (Cambridge, Massachusetts); Osman Berk Usta (Watertown, Massachusetts); Basak Elif Uygun (Cambridge, Massachusetts); Mustafa Korkut Uygun (Cambridge, Massachusetts); Sinem Perk (Chicago, Illinois)
ABSTRACT	The present invention generally relates to methods and compositions to determine viability of an organ for transplantation and other medical purposes. One aspect of the invention relates to a method for assessing the viability of an organ by measuring the energy parameters to determine the energy level of the organ by determining the stored cellular energy (e.g., ATP levels), and/or energy consumption over a particular time period of viability. The energy parameters can be compared to reference energy parameters as a highly accurate and reliable prediction of viable cell yield, and organ viability. Another aspect of the invention relates methods to preserve or extend the time period of viability of an organ any combination of (i) preservation perfusion of the organ to prevent ischemic damage, (ii) chemical metabolic suppression of the organ e.g., using metabolic suppressants, (iii) metabolic suppression by physical or environmental conditions, e.g., sub-zero non-freezing storage.
FILED	Wednesday, May 04, 2011
APPL NO	13/695459
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/42 (20130101) G01N 33/5091 (20130101)
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10575723 — Mapping of internal features on en face imagery

US 10575723	Kagemann, Jr. et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Lawrence E. Kagemann, Jr. (Pittsburgh, Pennsylvania); Joel Steven Schuman (Pittsburgh, Pennsylvania); Sayoko Eileen Moroi (Ann Arbor, Michigan)
ABSTRACT	The present disclosure describes systems and method for generating surgical maps that provide a surgeon with information regarding the placement of features of interest. More particularly, the system is configured to display optical coherence tomography (OCT) images to a medical professional. The medical professional can select anatomical features, biomarkers, and other features of interest within each of the OCT images. The system can then translate the location of the features of interest within the OCT images to an en face image to generate a map of the features that the medical professional can use for surgical guidance.
FILED	Wednesday, February 24, 2016
APPL NO	15/550021
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/16 (20130101) A61B 3/0025 (20130101) Original (OR) Class A61B 3/102 (20130101) A61B 3/1241 (20130101) A61B 2034/107 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/00781 (20130101)
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10575753 — White matter fibrography by synthetic magnetic resonance imaging

US 10575753	Jara
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) NIH Office of the Director (NIHOD)
APPLICANT(S)	BOSTON MEDICAL CENTER CORPORATION (Boston, Massachusetts)
ASSIGNEE(S)	BOSTON MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S)	Hernan Jara (Belmont, Massachusetts)
ABSTRACT	Methods of making a white matter fibrogram representing the connectome of the brain of a subject, comprising: (a) performing a multispectral multislice magnetic resonance scan on the brain of a subject, (b) storing image data indicative of a plurality of magnetic resonance weightings of each of a plurality of slices of the brain of the subject to provide directly acquired images, (c) processing the directly acquired images to generate a plurality of quantitative maps of the brain indicative of a plurality of qMRI parameters of the subject, (d) constructing a plurality of magnetic resonance images indicative of white matter structure from the quantitative maps, and (e) rendering a white matter fibrogram of the brain of the subject from the plurality of magnetic resonance images.
FILED	Thursday, May 30, 2019
APPL NO	16/427324
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) Original (OR) Class A61B 5/4076 (20130101) A61B 2576/026 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/5602 (20130101) G01R 33/5608 (20130101) G01R 33/56341 (20130101) Image Data Processing or Generation, in General G06T 2207/30016 (20130101)
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10575787 — Hydration sensor

US 10575787	Brown et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Elliott R. Brown (Beavercreek, Ohio); Weidong Zhang (Cary, North Carolina)
ASSIGNEE(S)	Wright State University (Dayton, Ohio)
INVENTOR(S)	Elliott R. Brown (Beavercreek, Ohio); Weidong Zhang (Cary, North Carolina)
ABSTRACT	A hydration sensor is provided that includes a circulator having a plurality of ports, an amplitude-modulated coherent source connected to a first port of the circulator, a rectifier or other power sensor connected to a second port of the circulator followed by an RF baseband low-noise amplifier, a coupling structure connected to the third port of the circulator, and a demodulator connected to the output of the rectifier. The hydration sensor can include an RF low noise amplifier between the circulator and rectifier, and/or a second amplitude modulator between the circulator and the coupling structure. The coupling structure can be either a guided-wave near-field structure or an interfacial capacitive or inductive element. In the former case, the hydration is determined by measuring the reflectivity of the guided-wave radiation, and in the latter case it is determined by measuring the change of reflectivity (through change of impedance) of the interfacial element.
FILED	Monday, April 17, 2017
APPL NO	15/489176
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/443 (20130101) A61B 5/4875 (20130101) A61B 5/7203 (20130101) A61B 5/7225 (20130101) A61B 5/7228 (20130101) Original (OR) Class
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10575788 — Compressive sensing of quasi-periodic signals using generative models

US 10575788	Gupta et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Sandeep Gupta (Phoenix, Arizona); Ayan Banerjee (Mesa, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Sandeep Gupta (Phoenix, Arizona); Ayan Banerjee (Mesa, Arizona)
ABSTRACT	Methods and systems are described for sensing and recovery of a biological signal using generative-model-based compressive sensing. A transformation is applied to sparsify the quasi-periodic signal removing morphology parameters and leaving temporal parameters. The sparsified signal is sampled and the sampled signal data is transmitted to a base station. A homotopy recovery algorithm is applied to the received sampled signal data by the base station to recover the temporal parameters of the biological signal. Generative modelling is applied using previously captured morphology parameters to generate a reconstructed signal. Finally, the reconstructed signal is adjusted and scaled based on the recovered temporal parameters to provide a reconstructed signal that is diagnostically equivalent to the original biological signal.
FILED	Wednesday, October 18, 2017
APPL NO	15/787534
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/0404 (20130101) A61B 5/0432 (20130101) A61B 5/0456 (20130101) A61B 5/681 (20130101) A61B 5/04011 (20130101) A61B 5/04014 (20130101) A61B 5/04525 (20130101) A61B 5/6823 (20130101) A61B 5/7232 (20130101) Original (OR) Class A61B 5/7264 (20130101) A61B 5/7275 (20130101) A61B 5/7278 (20130101) A61B 2560/0209 (20130101) A61B 2562/04 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) G16H 50/20 (20180101)
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10575792 — Systems and methods for cardiovascular-dynamics correlated imaging

US 10575792	Halter et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S)	THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S)	Ryan J. Halter (Lyme, New Hampshire); Keith D. Paulsen (Hanover, New Hampshire); Alexander Hartov (Enfield, New Hampshire)
ABSTRACT	A method for cardiovascular-dynamics correlated imaging includes receiving a time series of images of at least a portion of a patient, receiving a time series of cardiovascular data for the patient, evaluating correlation between the time series of images and the time series of cardiovascular data, and determining a property of the at least a portion of a patient, based upon the correlation. A system for cardiovascular-dynamics correlated imaging includes a processing device having: a processor, a memory communicatively coupled therewith, and a correlation module including machine-readable instructions stored in the memory that, when executed by the processor, perform the function of correlating a time series of images of at least a portion of a patient with a time series of cardiovascular data of the patient to determine a property of the at least a portion of a patient.
FILED	Monday, February 18, 2019
APPL NO	16/278703
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/024 (20130101) A61B 5/055 (20130101) A61B 5/0205 (20130101) A61B 5/0245 (20130101) A61B 5/0261 (20130101) A61B 5/0536 (20130101) A61B 5/02416 (20130101) A61B 5/7246 (20130101) A61B 5/7289 (20130101) Original (OR) Class A61B 5/14551 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/463 (20130101) A61B 6/469 (20130101) A61B 6/486 (20130101) A61B 6/487 (20130101) A61B 6/502 (20130101) A61B 6/503 (20130101) A61B 6/504 (20130101) A61B 6/5235 (20130101) A61B 6/5247 (20130101) A61B 6/5288 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) G06T 2207/30048 (20130101) G06T 2207/30068 (20130101)
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10575797 — Electromagnetic tracking system and methods of using same

US 10575797	Siewerdsen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Jeffrey H. Siewerdsen (Baltimore, Maryland); Jongheun Yoo (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Jeffrey H. Siewerdsen (Baltimore, Maryland); Jongheun Yoo (Baltimore, Maryland)
ABSTRACT	An electromagnetic tracking system including a patient support element and an electromagnetic field generator. The patient support element is superposed relative to the electromagnetic field generator, and the electromagnetic field generator is selectively moveable relative to the patient support element.
FILED	Friday, May 11, 2012
APPL NO	14/117100
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/061 (20130101) A61B 6/032 (20130101) A61B 6/0407 (20130101) Original (OR) Class A61B 6/508 (20130101) A61B 6/547 (20130101) A61B 6/582 (20130101) A61B 6/583 (20130101) A61B 6/4085 (20130101) A61B 6/4405 (20130101) A61B 6/4423 (20130101) A61B 6/4441 (20130101) A61B 34/20 (20160201) A61B 2034/2051 (20160201) Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 13/04 (20130101) A61G 2200/322 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/028 (20130101)
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10575851 — Atrial appendage ligation

US 10575851	Rogers et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America, as Represented by the the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S)	Toby Rogers (Washington, District of Columbia); Kaniska Ratnayaka (Washington, District of Columbia); Ozgur Kocaturk (Rockville, Maryland); Robert J. Lederman (Chevy Chase, Maryland)
ABSTRACT	This disclosure relates to devices and methods for manipulating, such as with a suction based traction device, a target anatomic structure inside the body and delivering an ligation device around the anatomic structure. In particular examples, the target structure can be an atrial appendage, and the devices and methods are for atrial appendage ligation.
FILED	Monday, October 27, 2014
APPL NO	15/030574
ART UNIT	3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/0469 (20130101) A61B 17/12013 (20130101) Original (OR) Class A61B 2017/00243 (20130101) A61B 2017/308 (20130101) A61B 2017/00867 (20130101)
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10576051 — Nitrated-fatty acids modulation of type II diabetes

US 10576051	Freeman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Bruce A. Freeman (Pittsburgh, Pennsylvania); Francisco J. Schopfer (Pittsburgh, Pennsylvania)
ABSTRACT	Nitro oleic acid and related metabolites are agonists of PPAR-γ. Surprisingly, nitro oleic acid is a more potent agonist of PPAR-γ, relative to nitro linoleic acid. Thus, nitro oleic acid and its metabolites, as well as their pharmaceutically acceptable salts and prodrug forms, are candidate therapeutics for the treatment of type-2 diabetes, which results from insulin resistance accompanying the improper functioning of PPAR-γ.
FILED	Wednesday, February 20, 2019
APPL NO	16/280704
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/20 (20130101) A61K 31/201 (20130101) Original (OR) Class A61K 31/201 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101)
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10576059 — Substituted phenylpyrrolecarboxamides with therapeutic activity in HIV

US 10576059	Debnath et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	New York Blood Center, Inc. (New York, New York); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Rockville, Maryland)
ASSIGNEE(S)	New York Blood Center, Inc. (New York, New York); The United States of America, as Represented by the Secretary, Department of Human Services (Bethesda, Maryland)
INVENTOR(S)	Asim Kumar Debnath (Fort Lee, New Jersey); Francesca Curreli (West New York, New Jersey); Peter D. Kwong (Bethesda, Maryland); Young Do Kwon (Bethesda, Maryland)
ABSTRACT	Substituted phenylpyrrolecarboxamide compounds such as those represented by Formula A can be used in the treatment of HIV infection and related conditions.
FILED	Wednesday, July 24, 2019
APPL NO	16/521327
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Acyclic or Carbocyclic Compounds C07C 25/00 (20130101) C07C 233/01 (20130101) Heterocyclic Compounds C07D 207/30 (20130101) C07D 207/34 (20130101) C07D 277/20 (20130101) C07D 403/12 (20130101) C07D 405/14 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101)
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10576066 — Histone deacetylase as a modulator of PDLI expression and activity

US 10576066	Villagra et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida)
ASSIGNEE(S)	H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida)
INVENTOR(S)	Alejandro V. Villagra (Tampa, Florida); Eduardo M. Sotomayor (Tampa, Florida)
ABSTRACT	Disclosed herein is a method for modulating Program Death Receptor Ligand 1 (PDL1) in a cancer cell, comprising contacting the cell with a composition comprising a histone deacetylase (HDAC) inhibitor. Also disclosed is a method for treating a tumor in a subject, comprising administering to the subject a therapeutically effective amount of a composition comprising a histone deacetylase (HDAC) inhibitor and a composition comprising a therapeutically effective amount of a Program Death Receptor Ligand 1 (PDL1) inhibitor, a Programmed Death 1 receptor (PD1) inhibitor, or a combination thereof.
FILED	Tuesday, June 05, 2018
APPL NO	16/000678
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/416 (20130101) A61K 31/422 (20130101) A61K 31/437 (20130101) Original (OR) Class A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/4045 (20130101) A61K 31/4406 (20130101) A61K 45/06 (20130101)
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10576091 — Tomatidine, analogs thereof, compositions comprising same, and uses for same

US 10576091	Adams et al.
FUNDED BY	Department of Veterans Affairs (DVA) DVA Office of Research and Development (DVAORD) Biomedical Laboratory Research and Development (BLRD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S)	UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S)	Christopher M. Adams (Iowa City, Iowa); Michael C. Dyle (Iowa City, Iowa); Michael Welsh (Riverside, Iowa)
ABSTRACT	In one aspect, the invention relates to methods for promoting muscle hypertrophy or decreasing adiposity by providing to an animal in need thereof an effective amount of a compound. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED	Friday, June 08, 2018
APPL NO	16/003184
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Fodder A23K 20/121 (20160501) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/10 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Steroids C07J 53/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101)
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10576093 — Neuroprotection by mitochondria-targeted metformin

US 10576093	Kanthasamy et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa); The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin)
ASSIGNEE(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa); The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin)
INVENTOR(S)	Anumantha Kanthasamy (Ames, Iowa); Balaraman Kalyanaraman (Wauwatosa, Wisconsin)
ABSTRACT	The present invention provides modified metformin compounds, particularly mito-metformin compounds, and pharmaceutical compositions thereof. Methods of using the compounds to provide neuroprotection and in the treatment and/or prevention of neurodegenerative diseases are also described.
FILED	Thursday, April 26, 2018
APPL NO	15/963648
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/662 (20130101) Original (OR) Class A61K 31/4425 (20130101)
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10576096 — Tumor-selective combination therapy

US 10576096	Hergenrother et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Board of Regents of the University of Texas System (Austin, Texas); The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Regents of the University of Texas System (Austin, Texas); The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Paul J. Hergenrother (Champaign, Illinois); David A. Boothman (Indianapolis, Indiana); Joseph S. Bair (Mullica Hill, New Jersey); Lifen Cao (Dallas, Texas); Jinming Gao (Plano, Texas); Xiumei Huang (Dallas, Texas); Xiuquan Luo (Plano, Texas); Xinpeng Ma (Dallas, Texas); Zachary R. Moore (Dallas, Texas); Elizabeth I. Parkinson (Champaign, Illinois)
ABSTRACT	The therapies described herein can be selectively lethal toward a variety of different cancer cell types and cancer conditions in a subject. The combination therapies described herein can be useful for the management, treatment, control, or adjunct treatment of diseases, where the selective legality is beneficial in chemotherapeutic therapy, particularly where the disease is accompanied by elevated levels of NQO1.
FILED	Wednesday, December 06, 2017
APPL NO	15/834052
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/131 (20130101) A61K 31/131 (20130101) A61K 31/353 (20130101) A61K 31/353 (20130101) A61K 31/706 (20130101) Original (OR) Class A61K 31/4738 (20130101) A61K 31/4738 (20130101) A61K 31/4745 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101)
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10576100 — Chitosan zinc oxide nanoparticle formulation for treating drug resistant bacteria

US 10576100	Mohapatra et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Shyam S. Mohapatra (Lutz, Florida); Alya Limayem (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Shyam S. Mohapatra (Lutz, Florida); Alya Limayem (Tampa, Florida)
ABSTRACT	A broad-based remediation mechanism against MRFs and alternative fecal indicators such as multidrug resistant Pseudomonas aeruginosa, including nanotechnology formulations and methodologies that may be used to develop novel treatment strategies against certain drug resistant bacterial strains. The current invention relates to the treatment of drug resistant bacteria from nosocomial infections, for example in hospitals and in food animals. The invention uses hybrid nanomaterials comprising oligo-chitosan and zinc oxide formulated as nanoparticles and micelles. The inventors unexpectedly found unique properties of very small oligomers of chitosan that effectively treat multi-drug resistant bacteria without compromising the balance of the beneficial flora in the physiological and ecological microenvironments in a host. Also, the combination of chitosan with zinc oxide demonstrated synergistic and unexpected effects in remediation of important food-borne bacteria including the resistant types.
FILED	Monday, October 15, 2018
APPL NO	16/159838
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 31/722 (20130101) Original (OR) Class A61K 33/30 (20130101) A61K 47/24 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/50 (20130101) C02F 2303/04 (20130101) C02F 2305/08 (20130101)
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10576115 — Oncolytic HSV vector

US 10576115	Uchida et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Hiroaki Uchida (Tokyo, Japan); Justus B. Cohen (Allison Park, Pennsylvania); Joseph C. Glorioso, III (Pittsburgh, Pennsylvania); Paola Grandi (Pittsburgh, Pennsylvania)
ABSTRACT	The present invention provides a recombinant herpes simplex virus (HSV), comprising (a) a mutation of the glycoprotein B (gB) at position 285 or 549, (b) a plurality of copies of one or more microRNA target sequences inserted into a locus of an HSV gene required for HSV replication, wherein said target sequence is the reverse complement of microRNA miR-124 and wherein said target sequence is present in the ICP4 gene, and (c) a transgene encoding a matrix metalloproteinase. The present invention also provides a method of killing a cancerous cell using a recombinant HSV according to the invention and a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a recombinant HSV according to the invention.
FILED	Wednesday, November 14, 2018
APPL NO	16/191141
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/763 (20130101) Original (OR) Class Peptides C07K 14/005 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16621 (20130101) C12N 2710/16622 (20130101) C12N 2710/16632 (20130101) C12N 2710/16641 (20130101) C12N 2710/16643 (20130101) C12N 2710/16645 (20130101) C12N 2710/16662 (20130101) C12N 2710/16671 (20130101)
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10576137 — Oligosialic acid derivatives, methods of manufacture, and immunological uses

US 10576137	Moe et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Children's Hospital and Research Center at Oakland (Oakland, California)
ASSIGNEE(S)	Children's Hospital Research Center at Oakland (Oakland, California)
INVENTOR(S)	Gregory R. Moe (Alameda, California); Brent T. Hagen (Oakland, California)
ABSTRACT	The invention relates to methods of producing, and compositions comprising, an isolated alpha (2→8) or (2→9) oligosialic acid derivative bearing a non-reducing end enriched for one or more de-N-acetyl residues and resistant to degradation by exoneuraminidase. A representative production method involves: (i) treating an alpha (2→8) or (2→9) oligosialic acid precursor having a reducing end and a non-reducing end with sodium borohydride under conditions for de-N-acetylating the non-reducing end; and (ii) isolating alpha (2→8) or (2→9) oligosialic acid derivative having one or more de-N-acetylated residues and a non-reducing end that is resistant to degradation by exoneuraminidase. Isolated alpha (2→8) or (2→9) oligosialic acid derivatives that comprise a non-reducing end de-N-acetyl residue are provided, as well as antibodies specific for the derivatives, compositions comprising the derivatives, kits, and methods of use including protection against and detection of E. coli K1 and N. meningitidis bacterial infection, and in diagnosing and treating cancer.
FILED	Monday, March 28, 2016
APPL NO	15/082905
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/095 (20130101) A61K 39/0258 (20130101) Original (OR) Class A61K 2039/6037 (20130101) A61K 2039/55505 (20130101) A61K 2039/55544 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 7/027 (20130101) C07H 13/04 (20130101) Peptides C07K 16/1217 (20130101) C07K 16/1282 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0006 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/22 (20130101) G01N 2333/245 (20130101) G01N 2400/02 (20130101)
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10576140 — Cholera toxin chimera and its use as a staph vaccine

US 10576140	Tinker
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Institute of General Medical Sciences (NIGMS) IDeA Networks of Biomedical Research Excellence (INBRE) Department of Agriculture (USDA)
APPLICANT(S)	Boise State University (Boise, Idaho)
ASSIGNEE(S)	Boise State University (Boise, Idaho)
INVENTOR(S)	Juliette Tinker (Eagle, Idaho)
ABSTRACT	The present invention relates to chimeric protein vaccines and methods of use thereof in the treatment of Staphylococcus aureus. One embodiment of the present invention provides a method of generating an immune response in a mammal, that includes administering to the mammal, a composition having a chimeric protein having at least one of: a portion of a cholera toxin, a portion of a heat-labile toxin, and a portion of a shiga toxin; and an antigen having at least one of: an antigenic material from S. aureus and an antigenic material from a S. aureus-specific polypeptide.
FILED	Wednesday, July 03, 2019
APPL NO	16/502675
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/085 (20130101) Original (OR) Class A61K 39/107 (20130101) A61K 2039/575 (20130101) A61K 2039/6037 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/25 (20130101) C07K 14/28 (20130101) C07K 14/31 (20130101) C07K 14/245 (20130101) C07K 2319/00 (20130101)
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10576165 — ST-246 liquid formulations and methods

US 10576165	Tyavanagimatt et al.
FUNDED BY	Department of Health and Human Services (HHS) Assistant Secretary for Preparedness and Response (ASPR) Biomedical Advanced Research and Development Authority (BARDA) National Institutes of Health (NIH)
APPLICANT(S)	SIGA TECHNOLOGIES, INC. (Corvallis, Oregon)
ASSIGNEE(S)	Siga Technologies Inc. (Corvallis, Oregon)
INVENTOR(S)	Shanthakumar R. Tyavanagimatt (Corvallis, Oregon); Melialani A. C. L. S. Anderson (Corvallis, Oregon); William Weimers (Corvallis, Oregon); Gopi Krishna Kasi (Lynnwood, Washington); N K Peter Samuel (Corvallis, Oregon); Tove C. Bolken (Keizer, Oregon); Dennis E. Hruby (Albany, Oregon)
ABSTRACT	The present invention provides for a novel liquid formulation for solubilizing poorly soluble ST-246 in cyclodextrins and a novel process of making the formulation.
FILED	Thursday, October 11, 2018
APPL NO	16/157343
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 31/715 (20130101) A61K 31/724 (20130101) A61K 31/724 (20130101) A61K 31/724 (20130101) A61K 31/4035 (20130101) A61K 31/4035 (20130101) A61K 47/10 (20130101) A61K 47/26 (20130101) A61K 47/40 (20130101) A61K 47/6951 (20170801) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24071 (20130101)
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10576181 — Polymer nanofiber scaffolds and uses thereof

US 10576181	Pokorski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Jonathan K Pokorski (Cleveland, Ohio); Eric Baer (Cleveland, Ohio); Sieun Kim (Cleveland, Ohio); Jia Wang (Cleveland, Ohio)
ABSTRACT	A polymer nanofiber scaffold includes a plurality of melt extruded nanofibers that are chemically modified to append surface functionality to the nanofibers.
FILED	Tuesday, July 03, 2018
APPL NO	16/026228
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/02 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/26 (20130101) Original (OR) Class A61L 15/44 (20130101) A61L 27/60 (20130101) A61L 2400/12 (20130101)
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10576187 — Layer by layer coated mesh for local release of bio-active proteins

US 10576187	Brown et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S)	Bryan Nicklaus Brown (Pittsburgh, Pennsylvania); Daniel Jordi Hachim Diaz (Pittsburgh, Pennsylvania)
ABSTRACT	The present invention relates to biomaterials coated with an active agent eluting coating, wherein implantation of the coated biomaterial results in reduced implant-related complications and/or improved integration of the biomaterial into the host tissue and further relates to kits containing the coated biomaterial. The present invention also relates to methods and kits for coating the biomaterial. It is based, at least in part, on the discovery that biomaterial coated with a cytokine eluting coating resulted in the shift of early stage macrophage polarization that were associated with positive long-term effects such as minimized capsule formation and improved tissue quality and composition as compared to uncoated biomaterials.
FILED	Wednesday, March 15, 2017
APPL NO	15/459993
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0063 (20130101) A61F 2210/0076 (20130101) A61F 2250/0067 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/2026 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/44 (20130101) A61L 17/005 (20130101) A61L 17/145 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 31/048 (20130101) Original (OR) Class A61L 31/048 (20130101) A61L 2420/02 (20130101) A61L 2420/08 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/002 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/18 (20130101) B05D 1/36 (20130101) B05D 7/56 (20130101) Compositions of Macromolecular Compounds C08L 23/10 (20130101)
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10576239 — System and methods for ambulatory generation of nitric oxide

US 10576239	Zapol et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S)	THIRD POLE, INC. (Waltham, Massachusetts)
ASSIGNEE(S)	Third Pole, Inc. (Waltham, Massachusetts)
INVENTOR(S)	David G. Zapol (San Francisco, California); Gregory W. Hall (Belmont, Massachusetts); Wolfgang Scholz (Beverly, Massachusetts); Benjamin Apollonio (Luneburg, Massachusetts); Frank Heirtzler (Londonderry, New Hampshire); Andrew Ferencz (Southborough, Massachusetts)
ABSTRACT	Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.
FILED	Monday, March 25, 2019
APPL NO	16/363505
ART UNIT	3785 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/04 (20130101) A61M 16/12 (20130101) Original (OR) Class A61M 16/022 (20170801) A61M 16/024 (20170801) A61M 16/0057 (20130101) A61M 16/0093 (20140204) A61M 16/101 (20140204) A61M 16/107 (20140204) A61M 16/202 (20140204) A61M 16/0666 (20130101) A61M 2202/0007 (20130101) A61M 2202/0057 (20130101) A61M 2202/0275 (20130101) A61M 2202/0275 (20130101) A61M 2202/0283 (20130101) A61M 2202/0283 (20130101) A61M 2205/05 (20130101) A61M 2205/054 (20130101) A61M 2205/80 (20130101) A61M 2205/125 (20130101) A61M 2205/502 (20130101) A61M 2205/3584 (20130101) A61M 2205/8206 (20130101) A61M 2209/088 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/32 (20130101)
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10576426 — Plasma separator apparatus and associated methods

US 10576426	Liu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Changchun Liu (Bala Cynwyd, Pennsylvania); Haim H. Bau (Swarthmore, Pennsylvania); Michael G. Mauk (Greenville, Delaware)
ABSTRACT	A plasma separator includes a vertical chamber with a membrane or membranes partially or fully covering the internal chamber walls and forming an inner cavity to accommodate whole blood. The plasma separator further includes a plasma collection space separated from the inner cavity with one or more membranes and a plasma removal port.
FILED	Thursday, December 18, 2014
APPL NO	15/105887
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3496 (20130101) A61M 2202/0415 (20130101) A61M 2205/70 (20130101) Separation B01D 61/147 (20130101) B01D 63/08 (20130101) B01D 63/087 (20130101) Original (OR) Class B01D 69/06 (20130101) B01D 2313/58 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/491 (20130101)
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10576446 — Enrichment of DNA sequencing libraries from samples containing small amounts of target DNA

US 10576446	Bustamante et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
INVENTOR(S)	Carlos D. Bustamante (Emerald Hills, California); Meredith L. Carpenter (San Mateo, California); Jason D. Buenrostro (Redwood City, California); William J. Greenleaf (Menlo Park, California)
ABSTRACT	Provided herein is a method for capturing DNA molecules in solution. The method may comprise: extracting DNA from a sample that comprises endogenous DNA and environmental DNA to produce extracted DNA; ligating universal adaptors to the extracted DNA; hybridizing the extracted DNA, in solution, with affinity-tagged RNA probes generated by: in vitro transcribing a library of fragmented reference genomic DNA that has been ligated to an RNA promoter adaptor, in the presence of an affinity-tagged ribonucleotide; binding the product with a capture agent that is tethered to a substrate in the presence of RNA oligonucleotides that are complementary to the adaptors, thereby capturing the hybridized DNA molecules on the substrate; washing the substrate to remove any unbound DNA molecules; and releasing the captured DNA molecules. A kit for performing the method is also provided.
FILED	Friday, May 02, 2014
APPL NO	14/653748
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/00585 (20130101) B01J 2219/00596 (20130101) B01J 2219/00722 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) C12N 15/1034 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 2525/143 (20130101) C12Q 2525/143 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2537/159 (20130101) C12Q 2537/159 (20130101) C12Q 2563/131 (20130101) C12Q 2563/131 (20130101)
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10576456 — Systems and methods of preparing stabilized lipid assemblies

US 10576456	Saavedra et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S)	Steven Scott Saavedra (Tucson, Arizona); Craig A. Aspinwall (Tucson, Arizona); Saliya N. Ratnayaka (Tucson, Arizona); Leonard Bright (Tucson, Arizona)
ABSTRACT	Direct polymerization of lipid monomers or polymer scaffolding of non-lipid monomers coupled with irradiation or redox polymerization performed at neutral pH resulted in stabilized lipid assemblies. An initiator-buffer component and NaHS03 redox mixture polymerizes reactive lipid monomers at near neutral pH conditions to preserve functionality of reconstituted membrane proteins. Improved stability of black lipid membranes (BLMs) is attained by chemical cross-linking of polymerizable, hydrophobic and commercially available non-lipid monomers partitioned into the suspended lipid membranes, and by suspending the BLMs across low surface energy apertures. Substrate apertures having low surface energy modifiers with amphiphobic properties facilitated a reproducible formation of BLMs by promoting interactions between the lipid tail and the substrate material. In addition, polymeric lipid bilayer membranes were prepared by photochemical or redox initiated polymerization of polymerizable lipid monomers, and disposed onto supporting substrates for use in chromatography columns.
FILED	Tuesday, June 30, 2015
APPL NO	15/318905
ART UNIT	1781 — Miscellaneous Articles, Stock Material
CURRENT CPC	Separation B01D 69/10 (20130101) B01D 69/105 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/286 (20130101) B01J 20/288 (20130101) B01J 20/3204 (20130101) B01J 20/3208 (20130101) B01J 20/3219 (20130101) B01J 20/3272 (20130101) Original (OR) Class B01J 20/3274 (20130101) B01J 20/3282 (20130101) B01J 20/3287 (20130101) B01J 20/3289 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/10 (20130101) B32B 3/266 (20130101) B32B 2307/20 (20130101) B32B 2307/70 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) B82Y 40/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/48 (20130101) C08F 30/08 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) G01N 2030/527 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 435/975 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24331 (20150115)
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10577303 — Reagents and methods for esterification

US 10577303	Raines et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Ronald T. Raines (Madison, Wisconsin); Nicholas Adam McGrath (Fairmont, Minnesota)
ABSTRACT	A method for esterification of one or more carboxylic acid groups in a compound containing one or more carboxylic acid groups wherein the esterification reagent is a diazo-compound of formula: wherein the R₁and R₂groups of the diazo compound are selected such that the corresponding organic compound of formula: exhibits a —C—H pKa value between 18 and 29 as measured in DMSO. Specific reagents and methods for esterification are provided. The esterification reagents provided exhibit high selectivity for esterification of carboxylic acid groups over reaction with amine, alcohol or thiol groups in the compound containing one or more carboxylic acid groups. The method can be used to selectively esterify carboxylic acid groups in peptides or proteins.
FILED	Friday, March 14, 2014
APPL NO	14/212381
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 67/18 (20130101) Original (OR) Class C07C 245/12 (20130101)
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10577349 — Quinolinones as inhibitors of translation initiation complex

US 10577349	Ronai et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California); The Royal Institution for the Advancement of Learning / McGill University (Montreal, Canada); The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland)
ASSIGNEE(S)	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California); THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (Montreal, Quebec, Canada); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
INVENTOR(S)	Ze'ev Ronai (La Jolla, California); Anthony B. Pinkerton (La Jolla, California); Yongmei Feng (La Jolla, California); Ivan Topisirovic (Quebec, Canada); Kevin Brown (Bethesda, Maryland); Christian A. Hassig (La Jolla, California)
ABSTRACT	Provided herein are compounds and pharmaceutical compositions comprising quinolinones. The quinolinones and compositions thereof are useful as eukaryotic translation initiation factor 4F (eIF4F) complex modulators.
FILED	Tuesday, March 01, 2016
APPL NO	15/554419
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Heterocyclic Compounds C07D 401/06 (20130101) C07D 401/14 (20130101) Original (OR) Class
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10577356 — Beta-arrestin-biased cannabinoid CB₁receptor agonists and methods for making and using them

US 10577356	Reggio et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	The University of North Carolina at Greensboro (Greensboro, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Greensboro (Greensboro, North Carolina)
INVENTOR(S)	Patricia H. Reggio (Greensboro, North Carolina); Derek M. Shore (Pine Hall, North Carolina); Dow P. Hurst (Greensboro, North Carolina)
ABSTRACT	The present invention provides compounds having a CB₁receptor-binding moiety and a directing moiety. In related aspects, the invention provides pharmaceutical compositions containing compounds of the invention, methods for inhibiting a pathway modulated in part by the CB₁receptor activity, and methods for treating a condition or disorder mediated in part by CB₁receptor activity. In certain embodiments, the compounds are compounds of Formula I. Methods of preparing compounds of Formula I are also described. In another aspect, the invention provides methods of identifying a selective agonist of the beta-arrestin pathway over the G-protein pathway.
FILED	Friday, October 05, 2018
APPL NO	16/153180
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 209/42 (20130101) C07D 401/12 (20130101) C07D 405/12 (20130101) Original (OR) Class C07D 405/14 (20130101) C07D 471/04 (20130101)
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10577357 — Inhibitors of LDLR-PCSK9 protein-protein interaction and methods of their use

US 10577357	Burgess
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Texas A and M University System (College Station, Texas)
ASSIGNEE(S)	The Texas A and M University System (College Station, Texas)
INVENTOR(S)	Kevin Burgess (College Station, Texas)
ABSTRACT	Compounds that disrupt the interaction between PCSK9 and LDLR, compositions that include the compounds, and methods for making and using the compounds and compositions.
FILED	Tuesday, September 19, 2017
APPL NO	16/334285
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/06 (20180101) Heterocyclic Compounds C07D 233/02 (20130101) C07D 403/14 (20130101) C07D 405/14 (20130101) Original (OR) Class
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10577368 — A3 adenosine receptor agonists

US 10577368	Jacobson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Saint Louis University (St. Louis, Missouri)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Saint Louis University (St. Louis, Missouri)
INVENTOR(S)	Kenneth A. Jacobson (Silver Spring, Maryland); Dilip K. Tosh (Rockville, Maryland); Daniela Salvemini (Chesterfield, Missouri)
ABSTRACT	Disclosed are compounds of the formula (I) and (II): which are A₃adenosine receptor agonists, pharmaceutical compositions comprising such compounds, and a method of use of these compounds, wherein X, Y, Z, R²-R⁶, and R¹⁰³-R¹⁰⁶are as defined in the specification. These compounds are selective to the A₃receptor, and are contemplated for use in the treatment or prevention of a number of diseases or conditions, for example, neuropathic pain.
FILED	Tuesday, April 10, 2018
APPL NO	15/949701
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Heterocyclic Compounds C07D 473/00 (20130101) C07D 473/34 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/02 (20130101)
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10577371 — Small molecule histone methyltransferase SUV39H1 inhibitor and uses thereof

US 10577371	Lu et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Augusta University Research Institute, Inc. (Augusta, Georgia); Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S)	Augusta University Research Institute, Inc. (Augusta, Georgia); Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Chunwan Lu (Augusta, Georgia); Iryna Lebedyeva (Augusta, Georgia); Kebin Liu (Augusta, Georgia)
ABSTRACT	Compositions for the inhibition of SUV39H1 methyltransferase activity and methods of use thereof are provided. The disclosed compositions may be used for treating certain types of cancer, inducing apoptosis in a cancer cell, increasing cell sensitivity to FasL-induced apoptosis, and overcoming cancer cell resistance to apoptosis and/or certain types of cancer immunotherapy.
FILED	Tuesday, September 18, 2018
APPL NO	16/134306
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/407 (20130101) A61K 31/407 (20130101) A61K 39/3955 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class Peptides C07K 16/2818 (20130101) C07K 2317/76 (20130101)
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10577377 — Substituted cyclopenta pyrimidine bicyclic compounds having antimitotic and/or antitumor activity and methods of use thereof

US 10577377	Gangjee
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Duquesne University of The Holy Spirit (Pittsburgh, Pennsylvania)
INVENTOR(S)	Aleem Gangjee (Allison Park, Pennsylvania)
ABSTRACT	The present invention provides substituted cyclopenta and cyclopentyl pyrimidine bicyclic compounds of Formula III, and pharmaceutically acceptable salts, prodrugs, solvates, and hydrates thereof, having antimitotic activity, anti-multidrug resistance activity, such as for example P-glycoprotein inhibition, and antitumor activity, and which inhibit paclitaxel sensitive and resistant tumor cells. Also provided are methods of utilizing these compounds for treating tumor cells and inhibiting mitosis of cancerous cells.
FILED	Thursday, March 09, 2017
APPL NO	15/453953
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Heterocyclic Compounds C07D 239/70 (20130101) C07D 487/04 (20130101) C07D 491/048 (20130101) Original (OR) Class
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10577395 — N-(hydrophobe-substituted) vancosaminyl [Ψ-[C(=NH) NH] Tpg⁴] vancomycin and [Ψ-[CH₂NH]Tpg⁴] vancomycin

US 10577395	Boger
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
ASSIGNEE(S)	THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S)	Dale L. Boger (La Jolla, California)
ABSTRACT	The total synthesis and evaluation of key analogs of vancomycin containing single atom changes in the binding pocket are disclosed as well as their peripherally modified, N-(hydrophobe-substituted) derivatives exemplified by a N-4-(4′-chlorobiphenyl)-methyl derivative and their pharmaceutically acceptable salts are disclosed. Their evaluation indicates the combined pocket and peripherally modified analogs exhibit a remarkable spectrum of antimicrobial activity and truly impressive potencies against both vancomycin-sensitive and -resistant bacteria, and likely benefit from two independent and synergistic mechanisms of action. A pharmaceutical composition containing a contemplated compound or its pharmaceutically acceptable salt is disclosed, as is a method of treating a bacterial infection in a mammal by administering an antibacterial amount of a contemplated compound or its salt as above to an infected mammal in need of treatment.
FILED	Friday, July 10, 2015
APPL NO	15/322605
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 9/008 (20130101) Original (OR) Class
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10577397 — Methods and compositions for protein delivery

US 10577397	Chatterjee et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The USA, as represented by the Secretary, Dept. of Health and Human Services (Rockville, Maryland)
ASSIGNEE(S)	The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland)
INVENTOR(S)	Deb Chatterjee (Potomac, Maryland); Stanislaw Jan Kaczmarczyk (Frederick, Maryland)
ABSTRACT	The present invention provides methods and compositions for protein delivery. The invention features virus like particles, methods of making virus like particles and methods of using virus like particles to deliver proteins to a cell, to provide protein therapy and to treat diseases or disorders. The invention also features methods of targeting a protein to a cell, methods of protein therapy and methods of treating diseases or disorders using a TUS protein, a NLS or NES identified from full length TUS.
FILED	Friday, July 20, 2018
APPL NO	16/041395
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/6901 (20170801) Peptides C07K 14/00 (20130101) C07K 14/005 (20130101) Original (OR) Class C07K 14/245 (20130101) C07K 2319/09 (20130101) C07K 2319/10 (20130101) C07K 2319/50 (20130101) C07K 2319/705 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/13043 (20130101) C12N 2760/20222 (20130101) C12N 2760/20223 (20130101) C12N 2810/6072 (20130101) C12N 2810/6081 (20130101)
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10577408 — Transduced T cells expressing human SSTR2 and application thereof

US 10577408	Jin
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Moonsoo Jin (New York, New York)
ABSTRACT	The present invention is directed to transduced T cells expressing at least 100,000 molecules of human somatostatin receptor 2 (SSTR2), which improves PET/CT imaging sensitivity. The present invention is also directed to transduced T cells expressing SSTR2 and chimeric antigen receptor (CAR). In one embodiment, the CAR is specific to human ICAM-1 and the CAR comprises a binding domain that is scFv of anti-human ICAM-1, or an I domain of the αL subunit of human lymphocyte function-associated antigen-1. In another embodiment, the CAR is specific to human CD19, and the CAR comprises a binding domain that is scFv of anti-human CD19. The present invention is further directed to using the above transduced T cells for monitoring T cell distribution in a patient by PET/CT imaging and/or treating cancer.
FILED	Friday, August 11, 2017
APPL NO	15/675419
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/1796 (20130101) A61K 39/0011 (20130101) A61K 51/083 (20130101) A61K 51/088 (20130101) A61K 2039/54 (20130101) A61K 2039/515 (20130101) Peptides C07K 14/723 (20130101) Original (OR) Class C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70553 (20130101) C07K 2319/03 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101)
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10577574 — Interconnections of multiple perfused engineered tissue constructs and microbioreactors, multi-microformulators and applications of the same

US 10577574	Wikswo et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Defense Threat Reduction Agency (DTRA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	John P. Wikswo (Brentwood, Tennessee); Frank E. Block, III (Nashville, Tennessee); Philip C. Samson (Nashville, Tennessee)
ABSTRACT	The invention relates to a system of fluidic valves and pumps and associated fluidic channels integratable into a bio-object microfluidics module. The module includes input and output buses; upstream and downstream interconnection bus control valves (CVs) coupled to the input and output buses, respectively. It may include arterial, venous, wash and waste bus lines, each connecting between the upstream and downstream interconnection bus CVs. It may also include an input CV connecting to the arterial bus line, upstream interconnection bus CV, bio-object and inlets, and an output CV connecting to the bio-object, input CV, downstream interconnection bus CV and outlets; and a pump connecting between the input CV and bio-object. The system of fluidic valves and pumps can be arranged to provide MicroFormulator functionality enabling precise mixtures of drugs, chemicals, or biochemicals to be delivered in a time-dependent fashion to biological entities housed in individual wells or chambers.
FILED	Wednesday, June 20, 2018
APPL NO	16/012900
ART UNIT	1799 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0247 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502715 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 23/44 (20130101) C12M 23/58 (20130101) C12M 29/00 (20130101) C12M 41/48 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/0045 (20130101)
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10577586 — Compositions and methods for modulating an immune response

US 10577586	Sharpe et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Arlene H. Sharpe (Cambridge, Massachusetts); Peter T. Sage (Cambridge, Massachusetts); Loise M. Francisco (Cambridge, Massachusetts)
ABSTRACT	The invention provides methods of modulating follicular regulatory T (TFR) cell-mediated immune responses, follicular helper T (TFH) cell-mediated immune responses or both, and the use of those methods in the treatment of diseases or conditions mediated by TFR or TFH cells. The invention also provides novel methods for identifying TFR and TFH cells in a population of cells. The invention also provides compositions comprising TFR cells that have enhanced suppressive activity as compared wild type TFR cells. The invention also provides compositions comprising T follicular regulatory (TFR) cells isolated from the peripheral blood of a subject wherein the composition is enriched for TFR cells. Methods of making and using the compositions of the invention to modulate an immune response are also provided.
FILED	Monday, February 05, 2018
APPL NO	15/888344
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 39/0005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 5/0637 (20130101) C12N 2501/515 (20130101) C12N 2501/599 (20130101)
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10577589 — Adenoviral assembly method

US 10577589	O'Shea et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Salk Institute for Biological Studies (La Jolla, California)
ASSIGNEE(S)	Salk Institute for Biological Studies (La Jolla, California)
INVENTOR(S)	Clodagh O'Shea (La Jolla, California); Colin Powers (La Jolla, California)
ABSTRACT	Methods of assembling modified adenoviruses, libraries of adenoviral gene modules and compositions thereof are provided herein.
FILED	Monday, November 09, 2015
APPL NO	14/935866
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/861 (20130101) C12N 2710/10043 (20130101) C12N 2710/10051 (20130101) C12N 2710/10351 (20130101) C12N 2800/30 (20130101) C12N 2800/70 (20130101)
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10577630 — Delivery and use of the CRISPR-Cas systems, vectors and compositions for hepatic targeting and therapy

US 10577630	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S)	Feng Zhang (Cambridge, Massachusetts); Le Cong (Cambridge, Massachusetts); Fei Ran (Cambridge, Massachusetts)
ABSTRACT	The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery systems and tissues or organ which are targeted as sites for delivery. Also provided are vectors and vector systems some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity and to edit or modify a target site in a genomic locus of interest to alter or improve the status of a disease or a condition.
FILED	Wednesday, December 16, 2015
APPL NO	14/971356
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/052 (20130101) A01K 2227/105 (20130101) A01K 2267/0312 (20130101) A01K 2267/0331 (20130101) A01K 2267/0362 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 48/0058 (20130101) A61K 48/0091 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/86 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 15/1082 (20130101) C12N 2710/24144 (20130101) C12N 2740/15043 (20130101) C12N 2750/14132 (20130101) C12N 2750/14143 (20130101) C12N 2750/14152 (20130101) Enzymes C12Y 301/00 (20130101)
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10577638 — Systems, devices, and methods for microbial detection and identification, and antimicrobial susceptibility testing

US 10577638	Srinivasan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Dental and Craniofacial Research (NIDCR) Non-Profit Organization (NPO) American Heart Association (AHA)
APPLICANT(S)	Anand Srinivasan (San Antonio, Texas); Anand K. Ramasubramanian (San Antonio, Texas); Jose L. Lopez-Ribot (San Antonio, Texas); Christopher R. Frei (San Antonio, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Anand Srinivasan (San Antonio, Texas); Anand K. Ramasubramanian (San Antonio, Texas); Jose L. Lopez-Ribot (San Antonio, Texas); Christopher R. Frei (San Antonio, Texas)
ABSTRACT	The present disclosure provides for systems, devices, products, and methods for detecting and identifying microbial organisms in a sample as well as testing antimicrobial susceptibility of microbial organisms.
FILED	Tuesday, September 23, 2014
APPL NO	15/023568
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Original (OR) Class
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10577651 — Method for nucleic acid sequencing

US 10577651	Williams
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (Menlo Park, California)
ASSIGNEE(S)	Pacific Biosciences of California, Inc. (Menlo Park, California)
INVENTOR(S)	John G. K. Williams (Lincolnville, Maine)
ABSTRACT	The present invention provides novel compositions, methods and apparatus for DNA sequencing that can be performed, e.g., in a two-electrode chamber. The present invention also provides a method for sequencing a nucleic acid comprising immobilizing a plurality of complexes comprising a target nucleic acid, a primer nucleic acid, and a polymerase onto a surface, contacting the surface with a plurality of charged particles comprising a nucleotide phosphate by applying an electric field, reversing the electric field to transport unbound charged particles away from the surface, and detecting the incorporation of a nucleotide phosphate into a single molecule of the primer nucleic acid.
FILED	Thursday, May 10, 2018
APPL NO	15/976701
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/005 (20130101) B01J 2219/00497 (20130101) B01J 2219/00576 (20130101) B01J 2219/00648 (20130101) B01J 2219/00722 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) C12Q 1/6825 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 2525/113 (20130101) C12Q 2525/117 (20130101) C12Q 2563/107 (20130101) C12Q 2563/149 (20130101) C12Q 2565/518 (20130101)
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10577656 — Diagnosis, prognosis and identification of potential therapeutic targets of multiple myeloma based on gene expression profiling

US 10577656	Shaughnessy, Jr. et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	BioVentures, LLC (Little Rock, Arkansas)
ASSIGNEE(S)	BIOVENTURES, LLC (Little Rock, Arkansas)
INVENTOR(S)	John D. Shaughnessy, Jr. (Roland, Arkansas); Bart Barlogie (Little Rock, Arkansas); Fenghuang Zhan (Salt Lake City, Utah)
ABSTRACT	Gene expression profiling is a powerful tool that has varied utility. It enables classification of multiple myeloma into subtypes and identifying genes directly involved in disease pathogensis and clinical manifestation. The present invention used gene expression profiling in large uniformly treated population of patients with myeloma to identify genes associated with poor prognosis. It also demonstrated that over-expression of CKS1B gene, mainly due to gene amplification that was determined by Fluorescent in-situ hybridization to impart a poor prognosis in multiple myleoma. It is further contemplated that therapeutic strategies that directly target CKS1B or related pathways may represent novel, and more specific means of treating high risk myeloma and may prevent its secondary evolution.
FILED	Friday, February 17, 2017
APPL NO	15/436230
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 25/00 (20190201) G16B 40/00 (20190201)
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10577662 — Methods for predicting anti-cancer response

US 10577662	Richardson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); THE TECHNICAL UNIVERSITY OF DENMARK (Lyngby, Denmark)
ASSIGNEE(S)	Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts); The Technical University of Denmark (Lyngby, Denmark)
INVENTOR(S)	Andrea L. Richardson (Chestnut Hill, Massachusetts); Zhigang C. Wang (Newton, Massachusetts); Daniel P. Silver (Wayland, Massachusetts); Zoltan Szallasi (Boston, Massachusetts); Nicolai Juul Birkbak (Copenhagen, Denmark); Aron Charles Eklund (Copenhagen, Denmark)
ABSTRACT	The present invention is based, in part, on the identification of novel methods for defining predictive biomarkers of response to anti-cancer drugs.
FILED	Thursday, October 20, 2016
APPL NO	15/298728
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101)
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10578580 — One-step capillary isoelectric focusing and mobilization of analytes

US 10578580	Dovichi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	UNIVERSITY OF NOTRE DAME DU LAC (South Bend, Indiana)
ASSIGNEE(S)	University of Notre Dame du Lac (South Bend, Indiana)
INVENTOR(S)	Norman Dovichi (South Bend, Indiana); Guijie Zhu (South Bend, Indiana); Liangliang Sun (South Bend, Indiana)
ABSTRACT	The invention provides a capillary isoelectric focusing (cIEF) system based on a sandwich injection method for automated chemical mobilization. This system was coupled with an electrokinetically pumped nanoelectrospray interface to a mass spectrometer. The nanoelectrospray emitter employed an acidic sheath electrolyte. To realize automated focusing and mobilization, a plug of ammonium hydroxide was first injected into the capillary, followed by a section of mixed sample and ampholyte. As focusing progressed, the NH₃H₂O section was titrated to lower pH buffer by the acidic sheath buffer. Chemical mobilization started automatically once the ammonium hydroxide was consumed by the acidic sheath flow electrolyte.
FILED	Friday, September 22, 2017
APPL NO	15/741883
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Peptides C07K 1/28 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) G01N 27/44717 (20130101) G01N 27/44743 (20130101) G01N 27/44795 (20130101) Original (OR) Class G01N 30/72 (20130101) G01N 2030/009 (20130101)
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10578608 — Tools to detect, track and target cancer cells in vivo

US 10578608	Reya
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Tannishtha Reya (San Diego, California)
ABSTRACT	Some embodiments include a genetically engineered cell comprising a nucleic acid encoding a detectable polypeptide operably linked to the Msi1 or Msi2 promoter and genetically engineered organisms comprising these genetically engineered cells.
FILED	Friday, October 14, 2016
APPL NO	15/294492
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 2217/072 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/0331 (20130101) A01K 2267/0393 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) A61K 49/0047 (20130101) Peptides C07K 14/43595 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) Enzymes C12Y 306/05002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/5011 (20130101) Original (OR) Class G01N 33/5073 (20130101) G01N 33/5088 (20130101)
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10578610 — Peptide regulators of mitochondrial fusion and methods of use

US 10578610	Mochly-Rosen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Washington University (St. Louis, Missouri)
ASSIGNEE(S)	Washington University (St. Louis, Missouri); Stanford University (Stanford, California)
INVENTOR(S)	Daria Mochly-Rosen (Menlo Park, California); Gerald W. Dorn, II (Hamilton, Ohio)
ABSTRACT	Mitofusin modulatory peptides are described which may function as activators or inhibitors of mitochondrial fusion. The sequences and compositions comprising the sequences are useful for treating diseases or disorders associated with mitofusin 1 (Mfn1) and/or mitofusin 2 (Mfn2) and mitochondrial dysfunction. Methods of treatment, pharmaceutical formulations and methods of identifying compounds that mimic the activity of the peptides for use in screening assays are also described.
FILED	Wednesday, September 20, 2017
APPL NO	15/710696
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/08 (20130101) C07K 14/705 (20130101) C07K 2319/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) Enzymes C12Y 306/05 (20130101) C12Y 310/01 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/547 (20130101) G01N 33/566 (20130101) G01N 33/582 (20130101) G01N 33/5079 (20130101) Original (OR) Class G01N 2500/00 (20130101)
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10578627 — Biochemical markers of red blood cell storage and toxicity

US 10578627	Zimring
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Bloodworks (Seattle, Washington)
ASSIGNEE(S)	Bloodworks (Seattle, Washington)
INVENTOR(S)	James Charles Zimring (Seattle, Washington)
ABSTRACT	Compositions and methods for determining post-transfusion survival or toxicity of red blood cells and the suitability of red blood cell units for transfusion by measuring the levels of one or more markers in a red blood cell sample are provided.
FILED	Wednesday, May 29, 2019
APPL NO	16/425768
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/80 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 2800/7066 (20130101)
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10578629 — Biomarkers for memory loss

US 10578629	Federoff et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	Georgetown University (Washington, District of Columbia); University of Rochester (Rochester, New York)
ASSIGNEE(S)	GEORGETOWN UNIVERSITY (Washington, District of Columbia); UNIVERSITY OF ROCHESTER (Rochester, New York)
INVENTOR(S)	Howard J. Federoff (Washington, District of Columbia); Mark E. Mapstone (Rochester, New York); Amrita K. Cheema (Washington, District of Columbia); Massimo S. Fiandaca (Washington, District of Columbia)
ABSTRACT	The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment. The methods comprise analyzing at least one plasma sample from the subject to determine a value of the subject's lipidomic profile, and comparing the value of the subject's lipidomic profile with the value of a normal lipidomic profile. A decrease in the value of the subject's lipidomic profile over normal values is indicative that the subject has an increased risk of suffering from memory impairment compared to a normal individual.
FILED	Thursday, April 21, 2016
APPL NO	15/134976
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 2405/00 (20130101) G01N 2405/04 (20130101) G01N 2570/00 (20130101) G01N 2800/52 (20130101) G01N 2800/2821 (20130101)
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10578696 — System, method and computer-accessible medium for spectroscopic localization using simultaneous acquisition of double spin and stimulated echoes

US 10578696	Gonen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	New York University (New York, New York)
ASSIGNEE(S)	New York University (New York, New York)
INVENTOR(S)	Oded Gonen (Leonardo, New Jersey); Assaf Tal (New York, New York)
ABSTRACT	Method, system and non-transitory computer-accessible medium can be provided for performing magnetic resonance spectroscopy for at least one structure. For example, with such method and/or computer-accessible medium, it is possible to receive information related to a substantially simultaneous acquisition of a stimulated echo pathway and a double spin echo associated with at least one portion of the at least one structure.
FILED	Thursday, April 02, 2015
APPL NO	14/677274
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/485 (20130101) Original (OR) Class
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10578703 — Full cycle rapid scan EPR and deconvolution

US 10578703	Tseytlin
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Colorado Seminary Watch Owns and Operates the University of Denver (Denver, Colorado)
ASSIGNEE(S)	Colorado Seminary Which Owns and Operates the University of Denver (Denver, Colorado)
INVENTOR(S)	Mark Tseytlin (Morgantown, West Virginia)
ABSTRACT	Full-cycle rapid scan (RS) electron paramagnetic resonance (EPR) can be performed without the instability of prior art methods and with a higher scan rate than traditional half-scan methods. In particular, a full scan is performed, but the constant RF driving B-field can be mathematically represented as two step functions, each corresponding to one half of a full scan cycle. This mathematical representation can be carried through the deconvolution such that two deconvolutions, one for the up cycle and one for the down cycle, can be performed. The solutions to these two deconvolutions can then be summed to give a single spectrum having a higher signal-to-noise ratio than half-cycle RS scans.
FILED	Friday, March 30, 2018
APPL NO	15/941936
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/60 (20130101) Original (OR) Class G01R 33/3607 (20130101) Electric Digital Data Processing G06F 9/445 (20130101)
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10580518 — Method and apparatus for performing similarity searching

US 10580518	Buhler et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	Washington University (St. Louis, Missouri)
ASSIGNEE(S)	WASHINGTON UNIVERSITY (St. Louis, Missouri)
INVENTOR(S)	Jeremy Daniel Buhler (St. Louis, Missouri); Roger Dean Chamberlain (St. Louis, Missouri); Mark Allen Franklin (St. Louis, Missouri); Kwame Gyang (St. Louis, Missouri); Arpith Chacko Jacob (St. Louis, Missouri); Praveen Krishnamurthy (St. Louis, Missouri); Joseph Marion Lancaster (St. Louis, Missouri)
ABSTRACT	A system and method for performing similarity searching is disclosed wherein programmable logic devices such as field programmable gate arrays (FPGAs) can be used to implement Bloom filters for identifying possible matches between a query and data. The Bloom filters can be implemented in a parallel architecture where the different parallel Bloom filters share access to the same memory units. Further, a hash table may be generated to map a set of strings to keys. In other examples, the hash table may be used to map a set of substrings to a position in a larger string.
FILED	Wednesday, January 11, 2017
APPL NO	15/403687
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Electric Digital Data Processing G06F 16/2255 (20190101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) G16B 50/00 (20190201) Original (OR) Class
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10580573 — Persistent-mode MRI magnet fabricated from reacted, monofilamentary MgB2 wires and joints

US 10580573	Hahn et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Seungyong Hahn (Tallahassee, Florida); Yukikazu Iwasa (Weston, Massachusetts); Juan Bascunan (Burlington, Massachusetts); John Peter Voccio (West Newton, Massachusetts); Jiayin Ling (Cambridge, Massachusetts); Jungbin Song (Brookline, Massachusetts); YoungJae Kim (Cambridge, Massachusetts)
ABSTRACT	A superconducting magnet and method for making a superconducting magnet are presented. The superconducting magnet is made by forming a coil from windings of a first wire comprising a reacted MgB₂monofilament, filling a cavity of a stainless steel billet with a Mg+B powder. Monofilament ends of the first wire and a similar second wire are sheared at an acute angle and inserted into the billet. A copper plug configured to partially fill the billet cavity is inserted into the billet cavity. A portion of the billet adjacent to the plug and the wires is sealed with a ceramic paste.
FILED	Monday, March 13, 2017
APPL NO	15/456928
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/3802 (20130101) G01R 33/3815 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/01 (20130101) H01F 6/06 (20130101) H01F 41/048 (20130101) Original (OR) Class Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/68 (20130101)
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10582286 — Method for treating debilitating hyperacusis

US 10582286	Eddins et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	David Alan Eddins (Odessa, Florida); Charles Craig Formby (Essex, Maryland); Stephen W. Armstrong (Burlington, Canada)
ASSIGNEE(S)	University of South Florida (Tampa, Florida); The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama); SoundsGood Labs, Inc. (, Canada)
INVENTOR(S)	David Alan Eddins (Odessa, Florida); Charles Craig Formby (Essex, Maryland); Stephen W. Armstrong (Burlington, Canada)
ABSTRACT	A system and method of treating hyperacusis is presented. The system uses a customizable, patient-specific, in-ear device combining sound attenuation with loudness suppression and a noise generator to expand the dynamic range of a patient. This device is used with novel software and counseling to provide a patient-specific treatment to hypersensitivity to sound.
FILED	Monday, June 24, 2019
APPL NO	16/450023
ART UNIT	2653 — Videophones and Telephonic Communications
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 11/08 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/1016 (20130101) Original (OR) Class H04R 25/75 (20130101) H04R 25/502 (20130101) H04R 25/505 (20130101) H04R 25/558 (20130101) H04R 2420/07 (20130101)
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Department of Defense (DOD)

10575710 — Super absorbing composite material, form factors created therefrom, and methods of production

US 10575710	Kumar et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) United States Marine Corps (USMC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	OCEANIT LABORATORIES, INC. (Honolulu, Hawaii)
ASSIGNEE(S)	OCEANIT LABORATORIES, INC. (Honolulu, Hawaii)
INVENTOR(S)	Ashavani Kumar (Honolulu, Hawaii); Sumil Singh Thapa (Honolulu, Hawaii)
ABSTRACT	Super absorbent material used for drying that integrates super absorbent non-woven fibrous mats with other material, as for example wicking material, are described. The fibrous mats consist of polymeric material embedded with particles of super absorbent polymer. The wicking material may be lightweight knitted fabric that actively absorbs and wicks liquid across the fabric surface. The materials are fabricated as single layer or multiple layers and demonstrate a variety of form factors suitable to the intended use. The super absorbent materials may incorporate additional functionalities, such as antifungal or antibacterial, for biomedical uses.
FILED	Friday, July 24, 2015
APPL NO	14/809090
ART UNIT	3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Domestic Washing or Cleaning; Suction Cleaners in General A47L 23/20 (20130101) Original (OR) Class Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/539 (20130101) A61F 2013/53908 (20130101) A61F 2013/530226 (20130101) A61F 2013/530481 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/022 (20130101) B32B 29/02 (20130101) B32B 2264/02 (20130101) B32B 2307/7145 (20130101)
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10576305 — Implants using ultrasonic backscatter for sensing physiological conditions

US 10576305	Maharbiz et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Michel M. Maharbiz (El Cerrito, California); Jose M. Carmena (Berkeley, California); Mekhail Anwar (San Francisco, California); Burak A. Ozilgen (Berkeley, California); Dongjin Seo (Albany, California); Federica Fava (Berkeley, California)
ABSTRACT	Described herein is an implantable device having a sensor configured to detect an amount of an analyte, a pH, a temperature, strain, or a pressure; and an ultrasonic transducer with a length of about 5 mm or less in the longest dimension, configured to receive current modulated based on the analyte amount, the pH, the temperature, or the pressure detected by the sensor, and emit an ultrasonic backscatter based on the received current. The implantable device can be implanted in a subject, such as an animal or a plant. Also described herein are systems including one or more implantable devices and an interrogator comprising one or more ultrasonic transducers configured to transmit ultrasonic waves to the one or more implantable devices or receive ultrasonic backscatter from the one or more implantable devices. Also described are methods of detecting an amount of an analyte, a pH, a temperature, a strain, or a pressure.
FILED	Wednesday, April 10, 2019
APPL NO	16/380944
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0031 (20130101) A61B 5/076 (20130101) A61B 5/686 (20130101) A61B 5/4836 (20130101) A61B 6/4258 (20130101) A61B 8/48 (20130101) A61B 8/085 (20130101) A61B 8/0808 (20130101) A61B 8/0875 (20130101) A61B 2505/05 (20130101) A61B 2560/0219 (20130101) A61B 2562/12 (20130101) A61B 2562/028 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 39/0208 (20130101) A61M 2205/04 (20130101) A61M 2205/825 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/372 (20130101) A61N 1/0534 (20130101) A61N 1/3605 (20130101) A61N 1/3787 (20130101) A61N 1/37205 (20130101) A61N 5/1071 (20130101) A61N 7/02 (20130101) Original (OR) Class A61N 2005/1087 (20130101) A61N 2007/0021 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/327 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 50/15 (20160201) H02J 50/90 (20160201)
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10576643 — Sensors for soft robots and soft actuators

US 10576643	Lessing et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Joshua Aaron Lessing (Cambridge, Massachusetts); George M. Whitesides (Newton, Massachusetts); Ramses V. Martinez (Somerville, Massachusetts); Dian Yang (Cambridge, Massachusetts); Bobak Mosadegh (New York, New York); Kevin C. Galloway (Somerville, Massachusetts); Firat Güder (Watertown, Massachusetts); Alok Suryavamsee Tayi (Somerville, Massachusetts)
ABSTRACT	A soft robotic device with one or more sensors is described. The sensor may be embedded in the soft body of the soft robotic device, attached to the soft body of the soft robotic device, or otherwise linked to the soft body of the soft robotic device.
FILED	Friday, August 21, 2015
APPL NO	15/503549
ART UNIT	3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) B25J 13/085 (20130101) B25J 13/087 (20130101) B25J 13/088 (20130101) B25J 15/0009 (20130101) B25J 15/12 (20130101) B25J 18/06 (20130101) Original (OR) Class
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10577082 — Cockpit control of a fixed wing aircraft

US 10577082	Baran et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S)	SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S)	Michael Paul Baran (Prospect, Connecticut); Nicholas Charles Visinski (Fairfield, Connecticut); Igor Cherepinsky (Sandy Hook, Connecticut)
ABSTRACT	A device and method for flying an aircraft is disclosed. A housing that is removably installable in a cockpit of the aircraft is installed in the cockpit. The housing includes a processor. The processor receives a flight measurement from the aircraft, determines a flight control parameter for flying the aircraft from the flight measurement, and operates a flight control device of the aircraft to implement the flight control parameter to fly the aircraft.
FILED	Friday, May 19, 2017
APPL NO	15/599735
ART UNIT	3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Aeroplanes; Helicopters B64C 13/18 (20130101) Original (OR) Class Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 23/00 (20130101)
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10577246 — Single walled carbon nanotube triode and methods of using same

US 10577246	Islam et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S)	United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S)	Ahmad Ehteshamul Islam (Beavercreek, Ohio); Benji Maruyama (Yellow Springs, Ohio)
ABSTRACT	A carbon nanotube triode apparatus includes a plurality of Horizontally Aligned Single Wall Carbon Nano Tubes (HA-SWCNT disposed on an electrically insulating thermally conductive substrate. A first contact is disposed on the substrate and electrically coupled to a first end of the HA-SWCNT. A second contact is disposed on the substrate and separated from a second end of the HA-SWCNT by a gap. A gate terminal is coincident with a plane of the substrate.
FILED	Wednesday, August 14, 2019
APPL NO	16/540318
ART UNIT	2811 — Semiconductors/Memory
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 32/158 (20170801) Original (OR) Class C01B 2202/02 (20130101) C01B 2202/08 (20130101) C01B 2202/34 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 9/025 (20130101) H01J 19/24 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0048 (20130101)
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10577401 — Nucleic acids for single-domain antibodies with thermal stability under cytoplasmic expression

US 10577401	Zabetakis et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Daniel Zabetakis (Brandywine, Maryland); George P. Anderson (Bowie, Maryland); Ellen R. Goldman (Germantown, Maryland); Kendrick Turner (Washington, District of Columbia); P. Audrey Brozozog Lee (Washington, District of Columbia)
ABSTRACT	A nucleic acid encodes a single-domain antibody (sdAb) is produced by causing a bacteria to express the sdAb into cytoplasm of the bacteria, wherein the sdAb is expressed as a fusion protein with the acid tail of α-synuclein. In embodiments, the protein is free of a periplasmic location tag. Such antibodies have the unexpected ability to refold after thermal denaturation.
FILED	Wednesday, March 27, 2019
APPL NO	16/365945
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/47 (20130101) Original (OR) Class C07K 16/16 (20130101) C07K 16/1271 (20130101) C07K 16/1278 (20130101) C07K 2317/94 (20130101) C07K 2317/569 (20130101) C07K 2319/00 (20130101)
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10577554 — Gas-filled stabilized particles and methods of use

US 10577554	Kheir et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S)	Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S)	John Kheir (Boston, Massachusetts); Brian D. Polizzotti (Boston, Massachusetts)
ABSTRACT	Provided herein are various gas-filled particles having a stabilized membrane that encapsulates the gas. Pharmaceutical compositions, methods of use and treatment, and methods of preparation are also described.
FILED	Friday, March 14, 2014
APPL NO	14/776774
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/5015 (20130101) A61K 9/5026 (20130101) A61K 9/5031 (20130101) A61K 9/5036 (20130101) A61K 47/6925 (20170801) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 10/18 (20130101) Original (OR) Class
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10577574 — Interconnections of multiple perfused engineered tissue constructs and microbioreactors, multi-microformulators and applications of the same

US 10577574	Wikswo et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Defense Threat Reduction Agency (DTRA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	John P. Wikswo (Brentwood, Tennessee); Frank E. Block, III (Nashville, Tennessee); Philip C. Samson (Nashville, Tennessee)
ABSTRACT	The invention relates to a system of fluidic valves and pumps and associated fluidic channels integratable into a bio-object microfluidics module. The module includes input and output buses; upstream and downstream interconnection bus control valves (CVs) coupled to the input and output buses, respectively. It may include arterial, venous, wash and waste bus lines, each connecting between the upstream and downstream interconnection bus CVs. It may also include an input CV connecting to the arterial bus line, upstream interconnection bus CV, bio-object and inlets, and an output CV connecting to the bio-object, input CV, downstream interconnection bus CV and outlets; and a pump connecting between the input CV and bio-object. The system of fluidic valves and pumps can be arranged to provide MicroFormulator functionality enabling precise mixtures of drugs, chemicals, or biochemicals to be delivered in a time-dependent fashion to biological entities housed in individual wells or chambers.
FILED	Wednesday, June 20, 2018
APPL NO	16/012900
ART UNIT	1799 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0247 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502715 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 23/44 (20130101) C12M 23/58 (20130101) C12M 29/00 (20130101) C12M 41/48 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/0045 (20130101)
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10577578 — Method for developing malaria sporozoites in vitro

US 10577578	Savransky et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	WALTER REED ARMY INSTITUTE OF RESEARCH DEPARTMENT OF THE ARMY (Washington, District of Columbia); Tatyana Savransky (Rockville, Maryland); Jackie Williams (Taft, Tennessee)
ASSIGNEE(S)	The Government of the United States as represented By the Secretary of the Army (Fort Detrick, Maryland)
INVENTOR(S)	Tatyana Savransky (Rockville, Maryland); Jackie Williams (Taft, Tennessee)
ABSTRACT	Described in this application is a method for producing Plasmodium sporozoites in a cell-free, mosquito-free in vitro culture-system. Compositions and methods resulting from applying the methods of the present invention are described.
FILED	Thursday, March 10, 2016
APPL NO	15/553328
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/10 (20130101) Original (OR) Class C12N 3/00 (20130101) C12N 13/00 (20130101)
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10577632 — Cell-free protein synthesis driven metabolic engineering for the production of 1-butanol

US 10577632	Jewett et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Michael Christopher Jewett (Evanston, Illinois); Ashty Stephen Karim (Chicago, Illinois)
ABSTRACT	Disclosed are cell-free systems for metabolic engineering, methods for cell-free metabolic engineering, kits for preparing the disclosed systems, and kits for performing the disclosed methods. The disclosed systems, methods, and kits may be utilized to prepare a chemical product and to optimize conditions for preparing a chemical product. The disclosed systems, methods, and kits also may be utilized for combinatorial cell-free metabolism engineering.
FILED	Tuesday, June 07, 2016
APPL NO	15/175497
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/16 (20130101) Original (OR) Class
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10577684 — Method for producing ultrafine-grained crystalline materials via electron beam processing

US 10577684	Reeves et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Mainstream Engineering Corporation (Rockledge, Florida)
ASSIGNEE(S)	Mainstream Engineering Corporation (Rockledge, Florida)
INVENTOR(S)	Ryan D. Reeves (Melbourne, Florida); Thomas M. Lasko (Merritt Island, Florida); Justin J. Hill (Merritt Island, Florida)
ABSTRACT	A process is disclosed for restructuring crystalline grain structure and grain size of a material to produce an ultrafine-grain structure. An electron beam source is configured in relation to specific properties of a material forming a solid body to selectively irradiate a surface and a subsurface of that body with electrons at desired locations on the body and to create at least one selectively localized molten pool of defined size in the body. Heat is generated sufficiently rapidly by the beam source to create thermal gradients of sufficient magnitude to permit the body outside of the pool to act as a heat sink and rapidly cool the at least one molten pool, whereby an ultrafine-grain structure and grain size is produced by freezing grain growth upon occurrence of crystal nucleation.
FILED	Monday, November 13, 2017
APPL NO	15/810895
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 15/0086 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Alloys C22C 14/00 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/183 (20130101) Original (OR) Class
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10577943 — Turbine engine airfoil insert

US 10577943	Marinelli et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Contracting Command (ACC) Redstone Arsenal (REDSTONE)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Andrea Terese Marinelli (Cambridge, Massachusetts); Robert Francis Manning (Newburyport, Massachusetts); Bhanu Mahasamudram Reddy (Boxford, Massachusetts)
ABSTRACT	An apparatus and method for improving the heat transfer coefficient for an engine component for a turbine engine such as an airfoil. The airfoil can include an outer wall defining an interior. A cooling passage can be formed in the interior defining a flow direction. An insert can be provided in the cooling passage to occupy a volume of the cooling passage to maintain a threshold Mach number for an airflow passing through the cooling passage to improve the heat transfer coefficient.
FILED	Thursday, May 11, 2017
APPL NO	15/592300
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) Original (OR) Class F01D 5/188 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/21 (20130101) F05D 2250/23 (20130101) F05D 2250/232 (20130101) F05D 2260/201 (20130101) F05D 2260/202 (20130101)
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10577976 — Mounting assembly with rotatable and/or translatable retainer pins

US 10577976	Izquierdo et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Life Cycle Management Center (AFLCMC)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Felix Izquierdo (Palm Beach Gardens, Florida); James P. Greenbaum (Bethesda, Maryland)
ABSTRACT	An assembly is provided that includes a first component, a second component, a plurality of retainers and a fastener. The first component is configured with a plurality of first apertures. The second component is configured with a plurality of second apertures. Each of the retainers includes a pin and an arm projecting out from an end of the pin. The pin of each of the retainers is mated with a respective one of the first apertures and a respective one of the second apertures. The fastener is configured to fixedly connect the arm of each of the retainers to the first component.
FILED	Monday, October 30, 2017
APPL NO	15/797307
ART UNIT	3632 — Static Structures, Supports and Furniture
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/26 (20130101) F01D 25/28 (20130101) F01D 25/243 (20130101) Original (OR) Class F01D 25/265 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/64 (20130101) F05D 2260/30 (20130101) F05D 2260/31 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 19/02 (20130101) F16B 37/044 (20130101)
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10578026 — Duct blocker seal assembly for a gas turbine engine

US 10578026	Lefevre et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Nicholas Lefevre (Vernon, Connecticut); John J. Korzendorfer (Glastonbury, Connecticut); Peter Balawajder (West Hartford, Connecticut); Paul W. Palmer (South Glastonbury, Connecticut); Paul J. Colucci (Glastonbury, Connecticut); Mahamoud Coulibaly (East Hartford, Connecticut)
ABSTRACT	A seal system for a gas turbine engine includes a cover plate with a radial flange; a seal carrier adjacent the cover plate; an outer compliant seal supported by the seal carrier; an inner compliant seal supported by the seal carrier, the inner compliant seal engaged with the radial flange; and a spring between the cover plate and the seal carrier.
FILED	Tuesday, February 13, 2018
APPL NO	15/895058
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/003 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/075 (20130101) Non-positive-displacement Pumps F04D 19/02 (20130101) F04D 27/0215 (20130101) F04D 29/083 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/90 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101)
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10578159 — Self-metering hydrostatic thrust bearing

US 10578159	Brooks
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Florida Turbine Technologies, Inc. (Jupiter, Florida)
ASSIGNEE(S)	Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S)	Stephen M Brooks (Jupiter, Florida)
ABSTRACT	A self-metering hydrostatic thrust bearing for a small gas turbine engine. The thrust bearing can provide thrust capacity in the fore and aft directions of a hydrostatic thrust bearing using a single source of air. The air supply is directed towards the loaded bearing and away from the unloaded bearing by the self-metering mechanism operated by the thrust load.
FILED	Friday, April 05, 2019
APPL NO	16/375999
ART UNIT	3656 — Material and Article Handling
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/22 (20130101) F01D 25/168 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/52 (20130101) F05D 2240/53 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 32/0614 (20130101) Original (OR) Class F16C 32/0692 (20130101)
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10578197 — Robotic arm and wrist mechanisms

US 10578197	Claffee et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA)
APPLICANT(S)	iRobot Corporation (Bedford, Massachusetts)
ASSIGNEE(S)	iRobot Corporation (Bedford, Massachusetts)
INVENTOR(S)	Mark R. Claffee (Methuen, Massachusetts); Timothy R. Ohm (Grover Beach, California); Erik Amaral (Lexington, Massachusetts); Annan M. Mozeika (Andover, Massachusetts)
ABSTRACT	A robot includes a support, a movable member coupled to the support to permit gimbal rotation about a pitch axis and a yaw axis, and first and second linear actuators connected to each of the support and the movable member and operable to rotate the movable member about the pitch axis and the yaw axis. The first linear actuator is pivotally attached to the movable member at a first pivot point. The second linear actuator is pivotally attached to the movable member at a second pivot point. The first and second pivot points are each angularly offset from the pitch axis and the yaw axis by about 45 degrees and are located on the same side of the pitch axis.
FILED	Wednesday, November 15, 2017
APPL NO	15/813933
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 17/0266 (20130101) Gearing F16H 25/20 (20130101) Original (OR) Class F16H 2025/2062 (20130101)
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10578369 — Thermal management using endothermic heat sink

US 10578369	Johnson et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S)	United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S)	Douglas J. Johnson (Kent, Ohio); Nicholas P. Niedbalski (Springfield, Ohio); Jamie S. Ervin (Springboro, Ohio); Soumya S. Patnaik (Mason, Ohio)
ABSTRACT	A thermal management system includes a slurry generator, an injector pump coupled to the slurry generator, a heat exchanger reactor coupled to the injector pump, wherein the heat exchanger reactor is adapted to subject a thermally expendable heat absorption material to a temperature above 60° C. and a pressure below 3 kPa, and wherein the expendable heat absorption material endothermically decomposes into a gaseous by-product. A vapor cycle system is coupled to the heat exchanger reactor and is operatively connected to a thermal load. A thermal energy storage system may be coupled to the vapor cycle system and the thermal load. The thermal energy storage system may isolate the heat exchanger reactor from thermal load transients of the thermal load.
FILED	Friday, February 23, 2018
APPL NO	15/903287
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Cosmonautics; Vehicles or Equipment Therefor B64G 1/423 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/06 (20130101) F28D 15/0266 (20130101) Original (OR) Class F28D 20/02 (20130101) F28D 20/003 (20130101) F28D 2021/0021 (20130101) F28D 2021/0022 (20130101) F28D 2021/0029 (20130101)
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10578440 — Atmospheric infrasonic sensing from an aircraft

US 10578440	Titovich
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Alexey Titovich (Poolesville, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Alexey Titovich (Poolesville, Maryland)
ABSTRACT	Exemplary practice of the present invention provides an air vehicle and at least one interferometric double-path fiber optic sensor connected with the air vehicle. Each fiber optic sensor includes a pair of optical fibers, viz., an optical sensing fiber and an optical reference fiber, in a parallel and propinquus relationship. The paired optical fibers of each fiber optic sensor are attached to the air vehicle either (i) circumferentially around the fuselage or (ii) lengthwise along the fuselage or (iii) span-wise along the wings and across the fuselage, and are configured whereby the sensing fiber is exposed to the atmosphere and the reference fiber is not. Each fiber optic sensor senses atmospheric infrasound but does not sense atmospheric wind noise, which is negated by incoherency associated with design lengthiness of the optical fiber pair. Noise and strain due to temperature, vibration, and propulsion are neutralized via interferometric common mode rejection.
FILED	Friday, August 04, 2017
APPL NO	15/669029
ART UNIT	3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/20 (20130101) Original (OR) Class Meteorology G01W 1/10 (20130101) G01W 2001/003 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0005 (20130101) G05D 1/101 (20130101) Traffic Control Systems G08G 5/0091 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101) H04L 67/025 (20130101)
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10578488 — Compact light dispersion system

US 10578488	Warren et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)	THE AEROSPACE CORPORATION (El Segundo, California)
ASSIGNEE(S)	The Aerospace Corporation (El Segundo, California)
INVENTOR(S)	David Wheeler Warren (Los Angeles, California); John A. Hackwell (Rancho Palos Verdes, California)
ABSTRACT	Disclosed herein are spectral imaging systems having an internally folded prism, which can have four different refracting surfaces. A first angle defines the spatial relationship between the first and second refracting surfaces. The first angle can have a range between 45-95 degrees. In some embodiments, the first angle can be 70 degrees. The spatial relationship of the third and fourth refracting surfaces can be defined by a second angle, which can be the same as the first angle. Finally, the spatial relationship of the second and third refracting surfaces can be defined by a third angle, which can have a range between 90-145 degrees. The prism index of refraction, the first, second, and third angles are selected such that TIR is achieved at two of the refracting surfaces. Additionally, these prism parameters are selected such that a 180 degrees fold of the optical path is achieved entirely within the prism.
FILED	Thursday, October 04, 2018
APPL NO	16/151999
ART UNIT	2886 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/40 (20130101) G01J 3/45 (20130101) G01J 3/0208 (20130101) G01J 3/2823 (20130101) Original (OR) Class G01J 2003/2826 (20130101)
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10578489 — Slow light imaging spectroscopy

US 10578489	Miles et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S)	Richard Miles (Princeton, New Jersey); Arthur Dogariu (Hamilton, New Jersey)
ABSTRACT	Disclosed is a process and device that enables ultra-high resolution one- and two-dimensional spatial imaging of Rayleigh, Raman and Thomson spectral features without the need for a spectrometer. The disclosed approach provides the capability for imaging of a single spectral feature such as a single rotational Raman line and the simultaneous elimination of background scattering, or for separating the rotational Raman image from the Rayleigh scattering. High collection efficiency provides the opportunity for single pulse time frozen images to be acquired.
FILED	Thursday, January 10, 2019
APPL NO	16/244619
ART UNIT	2886 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/2823 (20130101) G01J 3/4412 (20130101) Original (OR) Class
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10578528 — Compression test fixture and method therefor

US 10578528	Schaefer et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Contracting Command (ACC) National Aeronautics and Space Administration (NASA)
APPLICANT(S)	THE BOEING COMPANY (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Joseph D. Schaefer (St. Louis, Missouri); Brian P. Justusson (St. Peters, Missouri); Brian Kasperson (Seattle, Washington); David R. Barbee (St. Louis, Missouri)
ABSTRACT	A compression test fixture including a first specimen engagement member having a first channel, the first channel having a first depth; a second specimen engagement member having a second channel having a second depth that is different than the first depth; and at least one coupling member engaged to both the first specimen engagement member and the second specimen engagement member such that a gap is defined between the first specimen engagement member and the second specimen engagement member, where the first channel and the second channel support the test specimen within the gap such that at least one opposing major surface of the test specimen is visible within the gap.
FILED	Thursday, March 02, 2017
APPL NO	15/447245
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/02 (20130101) G01N 3/08 (20130101) Original (OR) Class G01N 33/00 (20130101) G01N 2033/0003 (20130101)
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10578623 — Peptide array quality control

US 10578623	Woodbury et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS OF BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Neal Woodbury (Tempe, Arizona); Stephen Johnston (Tempe, Arizona); Phillip Stafford (Phoenix, Arizona)
ABSTRACT	The present application provides arrays for use in immunosignaturing and quality control of such arrays. Also disclosed are peptide arrays and uses thereof for diagnostics, therapeutics and research.
FILED	Tuesday, May 29, 2018
APPL NO	15/991892
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) Original (OR) Class
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10578629 — Biomarkers for memory loss

US 10578629	Federoff et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	Georgetown University (Washington, District of Columbia); University of Rochester (Rochester, New York)
ASSIGNEE(S)	GEORGETOWN UNIVERSITY (Washington, District of Columbia); UNIVERSITY OF ROCHESTER (Rochester, New York)
INVENTOR(S)	Howard J. Federoff (Washington, District of Columbia); Mark E. Mapstone (Rochester, New York); Amrita K. Cheema (Washington, District of Columbia); Massimo S. Fiandaca (Washington, District of Columbia)
ABSTRACT	The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment. The methods comprise analyzing at least one plasma sample from the subject to determine a value of the subject's lipidomic profile, and comparing the value of the subject's lipidomic profile with the value of a normal lipidomic profile. A decrease in the value of the subject's lipidomic profile over normal values is indicative that the subject has an increased risk of suffering from memory impairment compared to a normal individual.
FILED	Thursday, April 21, 2016
APPL NO	15/134976
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 2405/00 (20130101) G01N 2405/04 (20130101) G01N 2570/00 (20130101) G01N 2800/52 (20130101) G01N 2800/2821 (20130101)
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10578748 — High-performance time transfer using time reversal (T3R)

US 10578748	Paek
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Eung Gi Paek (Germantown, Maryland)
ASSIGNEE(S)	Eung Gi Paek (Torrance, California)
INVENTOR(S)	Eung Gi Paek (Germantown, Maryland)
ABSTRACT	The basic concept of satellite-free time transfer using time reversal (T3R) has been invented and successfully demonstrated over long distance (about 4,000 km) with an accuracy of approximately 200 ns rms. The current invention describes new methods to drastically improve performance up to <10 ns rms—better than the current differential GPS, without satellites. The new method employs the Vernier concept utilizing the unique p-independence property of T3R irrespective of carrier frequencies. Also, a histogram method to automatically filter out extraneous data and allow high accuracy and a new method to extend the timing range of T3R beyond the pulse repetition period by removing ambiguity are proposed. A systematic way to obviate the signal blockage caused by transmit/receive window mismatch, is also proposed. Issues and solutions associated with the ionosphere are proposed, including 24-7 operation in adverse ionospheric conditions, such as the constantly changing ionosphere, multiple hops, static asymmetry, and jamming and spoofing.
FILED	Saturday, October 14, 2017
APPL NO	15/784117
ART UNIT	3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/22 (20130101) G01S 19/29 (20130101) G01S 19/44 (20130101) Original (OR) Class G01S 19/215 (20130101)
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10579092 — Global timing generator

US 10579092	Friedman et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Daniel J. Friedman (Sleepy Hollow, New York); Seongwon Kim (Old Tappan, New Jersey); Bipin Rajendran (Newark, New Jersey)
ABSTRACT	Aspects include a method for generating a signal in response to an event. The method includes receiving, from a clock signal generator, a clock signal, wherein the clock signal has a fixed clock period. The method further includes receiving an indication of a pulse and, responsive to receiving the indication of the pulse, generating an output comprising a high voltage having a starting time and an ending time. The starting time is a first time when the indication of the asynchronous event is received, and the ending time is a second time at one fixed clocked period from the starting time.
FILED	Tuesday, November 01, 2016
APPL NO	15/340401
ART UNIT	2186 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 1/08 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101)
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10579166 — Pointer acceleration system modeling

US 10579166	Malisoff et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Michael Malisoff (Baton Rouge, Louisiana); Fumin Zhang (Atlanta, Georgia); Jesse Paul Varnell (Atlanta, Georgia)
ABSTRACT	The present disclosure describes systems, methods, and apparatuses utilizing pointer acceleration system modeling. In one exemplary method, among others, such a method obtains, a closed loop pointer acceleration system model, in which the closed loop pointer acceleration system model is based on (1) a model describing user pointing motions integrated with (2) a model of pointer acceleration motions under operational conditions; obtains values for system parameters that include pointer acceleration profile parameters and operational condition parameters; and determines a set of pointer trajectories for a given acceleration profile having the pointer acceleration profile parameters and operational condition parameters.
FILED	Thursday, April 05, 2018
APPL NO	15/945895
ART UNIT	2692 — Selective Visual Display Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/038 (20130101) Original (OR) Class G06F 3/03543 (20130101) G06F 3/03547 (20130101) G06F 3/04847 (20130101)
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10579425 — Power aware scheduling of requests in 3D chip stack

US 10579425	Jacob et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Philip Jacob (Congers, New York); James P. Coghlan (Wappingers Falls, New York); Michael Grassi (Shokan, New York); Kirk Pospesel (Clinton Corners, New York); Marcel Schaal (Stuttgart, Germany); Douglas J. Joseph (Danbury, Connecticut)
ABSTRACT	A computer implemented method and system for managing power in a 3D chip stack formed of multiple memory layers each having a plurality memory banks and a plurality of Through-Silicon-Vias (TSVs) connecting the memory banks. The TSVs are arranged in a plurality of subsets, each subset of TSVs connecting a corresponding vertical stack of memory banks aligned across a plurality of memory layers. The method includes determining a power delivery budget for each subset of TSVs connecting the corresponding vertical stack of memory banks based on memory requests, keeping track of memory requests to the memory banks of each vertical stack of memory banks and scheduling the memory requests to the memory banks of each vertical stack of memory banks based on the power budget. The memory controller is configured with a scorecard scheduler to manage the memory requests based on the power budget.
FILED	Thursday, October 04, 2018
APPL NO	16/151850
ART UNIT	2196 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/48 (20130101) G06F 9/50 (20130101) G06F 9/4806 (20130101) G06F 9/4843 (20130101) G06F 9/4881 (20130101) G06F 9/4893 (20130101) Original (OR) Class G06F 9/5094 (20130101)
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10579911 — Systems and related methods employing directed energy and machine learning operable for enabling or protecting from non-destructive degradation or disruption of electro-optic(s) or sensors

US 10579911	Fitzsimmons et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Surface Warfare Center (NSWC)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S)	The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Tyler Fitzsimmons (Bloomington, Indiana); Betsy Marschand (Bloomington, Indiana); Clay Armstrong (Jasper, Indiana); Joshua Borneman (Bloomington, Indiana); Aaron Cole (Bloomington, Indiana); Lauren Christopher (Indianapolis, Indiana)
ABSTRACT	Various embodiments can include artificial learning counter surveillance (ALCS) or self-protection surveillance systems (SPSS) and related methods. Apparatuses and methods can include non-destructive electro-optic interference or protection systems as well non-destructive directed energy systems, a control system, and an analysis system for determining an optical system of interest and generating degradation or disruption effects using various equipment items and machine learning systems. Additionally, methods are also provided for determining degree of severity of degradation or disruption based on threshold definitions related to ability to use the optical system of interest for one or more specified applications.
FILED	Friday, March 09, 2018
APPL NO	15/916475
ART UNIT	2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/4257 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) Original (OR) Class G06K 9/00718 (20130101) G06K 9/6253 (20130101) Pictorial Communication, e.g Television H04N 7/181 (20130101)
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10580228 — Fault detection system and method for vehicle system prognosis

US 10580228	Korchev et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Autonomous Sustainment Technologies for Rotorcraft Operations Electrical (ASTRO-E)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Dmitriy Korchev (Irvine, California); Charles E. Martin (Thousand Oaks, California); Tsai-Ching Lu (Thousand Oaks, California); Steve Slaughter (Scottsdale, Arizona); Alice A. Murphy (Mesa, Arizona); Christopher R. Wezdenko (Mesa, Arizona)
ABSTRACT	A fault detection system including one or more sensors onboard a vehicle, the one or more sensors being configured to detect a predetermined characteristic of the vehicle and generate a plurality of sensor signals corresponding to the predetermined characteristic, and a processor onboard the vehicle and in communication with the one or more sensors, the processor being configured to generate an analysis model for the predetermined characteristic, the analysis model being trained by the processor with a training data set of fast Fourier transform vectors that are generated from the plurality of sensor signals obtained under normal operating conditions of the predetermined characteristic, and determine a health of a vehicle component corresponding to the predetermined characteristic with the analysis model.
FILED	Friday, July 07, 2017
APPL NO	15/643638
ART UNIT	3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/085 (20130101) G07C 5/0808 (20130101) Original (OR) Class G07C 5/0816 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) H04L 69/04 (20130101) H04L 69/40 (20130101)
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10580396 — Acoustically stiff wall

US 10580396	Quigley et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S)	James M. Quigley (Glenside, Pennsylvania); Christopher T. Buckingham (Haddon Heights, New Jersey)
ABSTRACT	An exemplary inventive acoustic wall panel includes a pair of congruent flat rectangular plates and a housing. The two plates adjoin at their respective vertical edges to form an angle Ø between the two plates, wherein 90°≤Ø<180°. Each plate has a material characteristic relating to acoustic reduction through the plate. Design of an inventive wall panel includes selection of the angle Ø and the respective plate materials, with an objective of producing counteractive acoustic vibratory motions in the two plates in response to sound waves impinging upon the inventive wall panel. Acoustic vibratory motion is induced in each plate whereby the respective vibratory motions tend to oppose each other, thereby reducing sound transmission across the inventive wall panel. The housing lends support to the two attached plates and facilitates connection of the inventive wall panel to another inventive wall panel or to a different structure.
FILED	Friday, April 07, 2017
APPL NO	15/481766
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/8209 (20130101) E04B 1/8409 (20130101) E04B 2001/742 (20130101) E04B 2001/829 (20130101) E04B 2001/8423 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/162 (20130101) G10K 11/175 (20130101) Original (OR) Class
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10580481 — Methods, circuits, systems, and articles of manufacture for state machine interconnect architecture using embedded DRAM

US 10580481	Sadredini et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	Elaheh Sadredini (Charlottesville, Virginia); Gholamreza Rahimi (Charlottesville, Virginia); Kevin Skadron (Charlottesville, Virginia); Mircea Stan (Charlottesville, Virginia)
ABSTRACT	A finite state machine circuit can include a plurality of rows of gain cell embedded Dynamic Random Access Memory (GC-eDRAM) cells that can be configured to store state information representing all N states expressed by a finite state machine circuit. A number of eDRAM switch cells can be electrically coupled to the plurality of rows of the GC-eDRAM cells, where the number of eDRAM switch cells can be arranged in an M×M cross-bar array where M is less than N, and the number of eDRAM switch cells can be configured to provide interconnect for all transitions between the all N states expressed by the finite state machine circuit.
FILED	Monday, January 14, 2019
APPL NO	16/246742
ART UNIT	2827 — Semiconductors/Memory
CURRENT CPC	Static Stores G11C 11/406 (20130101) G11C 11/4087 (20130101) G11C 11/4091 (20130101) G11C 11/4093 (20130101) Original (OR) Class G11C 11/4094 (20130101) Pulse Technique H03K 19/017581 (20130101)
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10580679 — Method of transfer printing and articles manufactured therefrom

US 10580679	Xia et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
ASSIGNEE(S)	THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S)	Qiangfei Xia (Amherst, Massachusetts); Peng Lin (Amherst, Massachusetts)
ABSTRACT	Disclosed herein is a method comprising disposing on a first substrate a two-dimensional exfoliatable material; patterning an exfoliatable material using a photoresist in a manner such that a portion of the photoresist remains in contact with the two-dimensional exfoliatable material after the patterning; disposing a polymer layer on the two-dimensional exfoliatable material to form a printing block; contacting a substrate with the printing block; and removing the polymer layer and the photoresist from the printing block to leave behind the patterned exfoliatable material on the substrate.
FILED	Thursday, September 22, 2016
APPL NO	15/762262
ART UNIT	1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00373 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/34 (20130101) C23C 14/042 (20130101) C23C 14/086 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 2201/123 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) G03F 7/0035 (20130101) G03F 7/40 (20130101) G03F 7/343 (20130101) G03F 7/2059 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/6835 (20130101) Original (OR) Class H01L 23/585 (20130101) H01L 2221/68363 (20130101)
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10580872 — Oxide heterostructures having spatially separated electron-hole bilayers

US 10580872	Eom et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Chang-Beom Eom (Madison, Wisconsin); Hyungwoo Lee (Madison, Wisconsin)
ABSTRACT	Oxide heterostructures that form spatially separated electron-hole bilayers are provided. Also provided are electronic devices that incorporate the oxide heterostructures. The oxide heterostructure includes a base layer of SrTiO₃, a polar layer of LaAlO₂, and a non-polar layer of SrTiO₃. Within the oxide heterostructures, a two-dimensional hole gas (2DHG) is formed at the interface between the non-polar layer and the polar layer and a two-dimensional electron gas (2DEG) is formed at the interface between the polar layer and the base layer.
FILED	Tuesday, May 16, 2017
APPL NO	15/596505
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) Original (OR) Class H01L 29/778 (20130101) H01L 29/7781 (20130101) H01L 29/66969 (20130101)
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10580924 — Graphene devices for terahertz detection and emission

US 10580924	Karabiyik et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Mustafa Karabiyik (Miami, Florida); Nezih Pala (Fort Lauderdale, Florida)
ASSIGNEE(S)	The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S)	Mustafa Karabiyik (Miami, Florida); Nezih Pala (Fort Lauderdale, Florida)
ABSTRACT	Devices and methods for Terahertz (THz) sensing/detection, imaging, spectroscopy, and communication are provided. A graphene-based field effect transistor (FET) can have a quality factor of greater than 400 and a responsivity of at least 400 Volts per Watt. A FET sensor can include a substrate, a gate disposed on the substrate, an insulation layer disposed on the gate and the substrate, a source terminal and a drain terminal disposed on the substrate, and a graphene layer disposed on the insulation layer.
FILED	Thursday, February 28, 2019
APPL NO	16/288748
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/1606 (20130101) H01L 31/028 (20130101) H01L 31/1136 (20130101) Original (OR) Class H01L 31/022408 (20130101)
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10581034 — Battery assembly

US 10581034	Bayles et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Science Applications International Corporation (McLean, Virginia)
ASSIGNEE(S)	Science Applications International Corporation (Reston, Virginia)
INVENTOR(S)	Gary A. Bayles (Millersville, Maryland); Charles R. Longabaugh (Hazleton, Indiana)
ABSTRACT	A battery assembly may include bus strips located on one or more sides and displaced ends of battery cells. The battery assembly may comprise a heater. The battery assembly may comprise one or more refractory panels. A refractory panel may comprise weakened regions corresponding to battery cells.
FILED	Wednesday, March 07, 2018
APPL NO	15/914391
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/022 (20130101) H01M 2/029 (20130101) Original (OR) Class H01M 2/204 (20130101) H01M 2/206 (20130101) H01M 2/1077 (20130101) H01M 2/1094 (20130101) H01M 2/1241 (20130101) H01M 10/486 (20130101) H01M 10/0525 (20130101) H01M 10/615 (20150401) H01M 10/653 (20150401) H01M 10/658 (20150401) H01M 10/6554 (20150401) H01M 10/6571 (20150401) H01M 2200/103 (20130101)
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10581085 — Perovskite compounds for stable, high activity solid oxide fuel cell cathodes and other applications

US 10581085	Jacobs et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Office of Cyberinfrastructure (OCI)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Ryan Matthew Jacobs (Madison, Wisconsin); Dane Morgan (Middleton, Wisconsin)
ABSTRACT	Solid oxide fuel cells (SOFCs) are provided. A SOFC may comprise a cathode, an anode, and a solid oxide electrolyte between the anode and the cathode, wherein the cathode comprises a perovskite compound. The perovskite compound may be characterized by a log k* value which is less negative than about −6.0 cm/s; an energy above the convex hull of less than about 40 meV/(formula unit); a bandgap of about 0 and a charge transfer gap of about 0.
FILED	Tuesday, December 20, 2016
APPL NO	15/384482
ART UNIT	1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9033 (20130101) Original (OR) Class H01M 2004/8689 (20130101) H01M 2008/1293 (20130101)
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10581127 — Anaerobic aluminum-water electrochemical cell

US 10581127	McKay et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Ian Salmon McKay (Seattle, Washington); Ruaridh R. Macdonald (London, United Kingdom); Thomas B. Milnes (Beverly, Massachusetts)
ABSTRACT	An anaerobic aluminum-water electrochemical cell is provided. The electrochemical cell includes: a plurality of electrode stacks, each electrode stack comprising an aluminum or aluminum alloy anode, and at least one cathode configured to be electrically coupled to the anode and having a surface characterized by an electrochemical roughness factor of at least 5 and a mean pore diameter of at least 50 μm; one or more physical separators between each electrode stack adjacent to the cathode; a housing configured to hold the electrode stacks, an electrolyte, and the physical separators; and a water injection port, in the housing, configured to introduce water into the housing.
FILED	Tuesday, August 07, 2018
APPL NO	16/057285
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/06 (20130101) H01M 4/12 (20130101) H01M 4/463 (20130101) H01M 6/04 (20130101) H01M 6/34 (20130101) H01M 6/46 (20130101) H01M 12/02 (20130101) H01M 12/04 (20130101) Original (OR) Class H01M 2004/021 (20130101) H01M 2004/027 (20130101) H01M 2300/0014 (20130101)
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10581128 — Anaerobic aluminum-water electrochemical cell

US 10581128	McKay et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Ian Salmon McKay (Seattle, Washington); Ruaridh R. Macdonald (London, United Kingdom); Thomas B. Milnes (Beverly, Massachusetts)
ABSTRACT	An anaerobic aluminum-water electrochemical cell that includes: a plurality of electrode stacks, each electrode stack featuring an aluminum or aluminum alloy anode, and at least one cathode configured to be electrically coupled to the anode; one or more physical separators between each electrode stack adjacent to the cathode; a housing configured to hold the electrode stacks, an electrolyte, and the physical separators; a water injection port, in the housing, configured to introduce water into the housing. The electrochemical cell also includes an amount of hydroxide base sufficient to form an electrolyte having a hydroxide base concentration of at least 0.05 M to at most 3 M when water is introduced between the anode and at least one cathode of the electrochemical cell. The aluminum or aluminum alloy of the anode is substantially free of titanium and boron.
FILED	Tuesday, August 07, 2018
APPL NO	16/057117
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/469 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/14 (20130101) H01M 2/0255 (20130101) H01M 4/463 (20130101) H01M 4/9041 (20130101) H01M 8/18 (20130101) H01M 8/20 (20130101) H01M 8/083 (20130101) H01M 8/227 (20130101) H01M 8/0482 (20130101) H01M 8/0693 (20130101) H01M 8/04186 (20130101) H01M 8/04283 (20130101) H01M 8/04828 (20130101) H01M 12/04 (20130101) H01M 12/08 (20130101) Original (OR) Class H01M 2300/0014 (20130101)
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10581129 — Anaerobic aluminum-water electrochemical cell

US 10581129	McKay et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Ian Salmon McKay (Seattle, Washington); Ruaridh R. Macdonald (London, United Kingdom); Thomas B. Milnes (Beverly, Massachusetts)
ABSTRACT	An anaerobic aluminum-water electrochemical cell is provided. The electrochemical cell includes: a plurality of electrode stacks, each electrode stack including an aluminum or aluminum alloy anode, and at least one cathode configured to be electrically coupled to the anode; one or more physical separators between each electrode stack adjacent to the cathode; a housing configured to hold the electrode stacks, an electrolyte, and the physical separators; a water injection port, in the housing, configured to introduce water into the housing, and an amount of hydroxide base sufficient to form an electrolyte having a hydroxide base concentration of at least 0.5% to at most 13% of the saturation concentration when water is introduced between the anode and the least one cathode. The aluminum or aluminum alloy of the anode is substantially free of titanium and boron.
FILED	Tuesday, August 07, 2018
APPL NO	16/057131
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/469 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/14 (20130101) H01M 2/0255 (20130101) H01M 4/463 (20130101) H01M 4/9041 (20130101) H01M 8/18 (20130101) H01M 8/20 (20130101) H01M 8/083 (20130101) H01M 8/227 (20130101) H01M 8/0482 (20130101) H01M 8/0693 (20130101) H01M 8/04186 (20130101) H01M 8/04283 (20130101) H01M 8/04828 (20130101) H01M 12/04 (20130101) H01M 12/08 (20130101) Original (OR) Class H01M 2300/0014 (20130101)
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10581135 — Circuits and methods for non-reciprocal circulators and transceivers using same

US 10581135	Reiskarimian et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Negar Reiskarimian (New York, New York); Harish Krishnaswamy (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Negar Reiskarimian (New York, New York); Harish Krishnaswamy (New York, New York)
ABSTRACT	In accordance with some embodiments, non-reciprocal circulators are provided, the circulators comprising: a 3λX/4-long ring section having a first end and a second end, wherein λ is an operating wavelength of the non-reciprocal circulator; and a N-path filter having a first port, a second port, and N-paths, each of the N-paths being connected to the first port and the second port. In some of these embodiments, the 3λ/4-long ring section includes a transmit port, an antenna port, and a receive port. In some of these embodiments, the transmit port is λ/4 away from the antenna port. In some of these embodiments, the antenna port is λ/4 away from the receive port. In some of these embodiments, the receive port is at the first port of the N-path filter.
FILED	Wednesday, December 07, 2016
APPL NO	15/774410
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/011 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/397 (20130101) Original (OR) Class H01P 5/222 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/00 (20130101) H03H 7/52 (20130101) H03H 11/16 (20130101) Transmission H04B 1/44 (20130101) H04B 1/525 (20130101) H04B 3/40 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/16 (20130101)
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10581176 — Thin-film sensor antenna

US 10581176	Puchades et al.
FUNDED BY	Central Intelligence Agency (CIA) Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	Ivan Puchades (Honeoye Falls, New York); Brian J. Landi (Rochester, New York); Jamie E. Rossi (Penfield, New York); Cory D. Cress (Alexandria, Virginia)
ASSIGNEE(S)	Rochester Institute of Technology (Rochester, New York)
INVENTOR(S)	Ivan Puchades (Honeoye Falls, New York); Brian J. Landi (Rochester, New York); Jamie E. Rossi (Penfield, New York); Cory D. Cress (Alexandria, Virginia)
ABSTRACT	A sensor antenna including a thin film material constructed in the shape of an antenna having a response, the material including a sheet resistance capable of being modified by an external stimulus where the antenna response varies over a range of sheet resistance values; method of making a sensor antenna; system including a sensor antenna; and method for operating a thin film sensor antenna including providing a thin film sensor antenna; exposing the sensor antenna to an external stimulus, simultaneously sensing the external stimulus while varying the sensor antenna response, measuring the change in the sensor antenna response, and correlating the measured response to a known change in the stimulus are disclosed.
FILED	Wednesday, May 10, 2017
APPL NO	15/591712
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/16 (20130101) Antennas, i.e Radio Aerials H01Q 1/368 (20130101) H01Q 21/0087 (20130101) Original (OR) Class Transmission H04B 17/12 (20150115) H04B 17/21 (20150115)
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10581178 — Integrated infrared optical antenna and polaronic organic transducer sensor

US 10581178	Vella et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S)	United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S)	Jarrett H Vella (New Carlisle, Ohio); John S Derov (Beavercreek, Ohio); Mohammad I Vakil (Beavercreek, Ohio)
ABSTRACT	An antenna array is provided including a substrate, a metal ground plane proximate the substrate, and a dielectric layer proximate the metal ground plane. A first plurality of antenna elements including polaronic organic transducer elements is proximate the dielectric layer and connected in series. A second plurality of antenna elements including polaronic organic transducer elements is proximate the dielectric layer and also connected in series. The first and second plurality of antenna elements are electrically isolated. The antenna elements of the first plurality of antenna elements are configured to detect a first wavelength, while the antenna elements of the second plurality of antenna elements are configured to detect a second wavelength, different from the first wavelength.
FILED	Monday, February 06, 2017
APPL NO	15/424961
ART UNIT	2812 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/28 (20130101) H01L 51/00 (20130101) H01L 51/0036 (20130101) Antennas, i.e Radio Aerials H01Q 21/065 (20130101) Original (OR) Class
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10581307 — Hybrid surface magnet machine

US 10581307	Sudhoff et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Scott D. Sudhoff (West Lafayette, Indiana); Steve D. Pekarek (West Lafayette, Indiana); Omar Abdul Rahman Laldin (Inglewood, California)
ABSTRACT	A hybrid electrical machine containing surface mounted magnets which includes a magnetically permeable cylindrically shaped stator assembly having at least one stator winding formed about a plurality of stator teeth, a rotor assembly concentrically disposed within the stator assembly, including a magnetically permeable rotor backiron, a rotational drive mechanism coupled to the rotor backiron, and a plurality of protruding rotor poles, each including a magnetically permeable pole support assembly, a winding provided around the pole support assembly, and a radially magnetized permanent magnet assembly disposed about the pole support assembly.
FILED	Monday, April 15, 2019
APPL NO	16/384067
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Dynamo-electric Machines H02K 16/02 (20130101) H02K 21/042 (20130101) Original (OR) Class Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 25/024 (20160201)
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10581347 — Manually operated piezoelectric energy harvesting electronic circuitry

US 10581347	Rastegar
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Armament Research, Development and Engineering Center (ARDEC)
APPLICANT(S)	Jahangir S Rastegar (Stony Brook, New York)
ASSIGNEE(S)	OMNITEK PARTNERS LLC (Ronkonkoma, New York)
INVENTOR(S)	Jahangir S Rastegar (Stony Brook, New York)
ABSTRACT	An electrical energy harvesting device for harvesting electrical energy from a pulsed impact loading event. The device including: a piezoelectric element configured to be loaded and unloaded to a first load level by the pulsed impact loading event; and a first inductor coupled to the piezoelectric element configured to be loaded and unloaded to a second load level by the pulsed impact loading event, wherein the piezoelectric element and the first inductor together operate as a first inductor/capacitor (LC) resonant circuit having a first resonance frequency and wherein the loading of the first inductor lags in time the loading of the piezoelectric element.
FILED	Tuesday, January 24, 2017
APPL NO	15/414588
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Heterocyclic Compounds C07D 207/325 (20130101) C07D 403/10 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 132/08 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 11/02 (20130101) Electric Machines Not Otherwise Provided for H02N 2/181 (20130101) Original (OR) Class H02N 2/183 (20130101)
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10581521 — Dual-mode imaging receiver

US 10581521	Shaw et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)	Gary A. Shaw (Westford, Massachusetts); Lawrence M. Candell (Arlington, Massachusetts); Pablo I. Hopman (Harvard, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Gary A. Shaw (Westford, Massachusetts); Lawrence M. Candell (Arlington, Massachusetts); Pablo I. Hopman (Harvard, Massachusetts)
ABSTRACT	A dual-mode imaging receiver (DMIR) can acquire and maintain SOA free-space optical communication (FSOC) links without a precision mechanical gimbal. Unlike other FSOC technologies, a DMIR can operate without precise spatial alignment and calibration of the transmitter's or receiver's spatial encoders (precision pointing) in static (fixed point to point) geometries. Instead, a DMIR uses electronic receive beam selection to acquire and track transmitters with coarse mechanical pointing and a single aperture. And because the DMIR can operate with just one aperture, it does not need a beacon at the transmitter since it does not transition from a wide field-of-view acquisition aperture to a narrow field-of-view detection and decoding aperture even in dynamic geometries.
FILED	Thursday, August 30, 2018
APPL NO	16/117853
ART UNIT	2637 — Optical Communications
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 2001/442 (20130101) Measurement of Nuclear or X-radiation G01T 1/24 (20130101) Transmission H04B 10/11 (20130101) Original (OR) Class H04B 10/60 (20130101) H04B 10/1121 (20130101) Pictorial Communication, e.g Television H04N 5/2258 (20130101) H04N 5/2259 (20130101) H04N 5/3415 (20130101) H04N 5/37455 (20130101) H04N 7/22 (20130101)
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10581632 — Data transfer filter

US 10581632	Linderman
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Government of the United States, as represented by the Secretary of the Air Force (Rome, New York)
ASSIGNEE(S)	Goverrnment of the United States of America as Represented by the Secretary of The Air Force (Washington, District of Columbia)
INVENTOR(S)	Mark Herron Linderman (Rome, New York)
ABSTRACT	A device has a host port, a remote terminal (RT), an incoming line driver, an outgoing line driver, and at least one of an incoming message filter and an outgoing message filter. The host port communicatively couples to a shared host bus. The RT port communicatively couples to the RT. The incoming message filter receives an incoming host message from the host port and generates a filtered host message from the incoming host message employing at least one host message rule. The outgoing message filter receives an outgoing RT message from the RT port and generates a filtered RT message from the outgoing RT message employing at least one RT message rule. The incoming line driver communicates the filtered host message to the RT port. The outgoing line driver communicates the filtered RT message to the host port.
FILED	Friday, March 31, 2017
APPL NO	15/475195
ART UNIT	2181 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 13/404 (20130101) G06F 13/4072 (20130101) G06F 13/4282 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/4013 (20130101) Original (OR) Class H04L 12/40013 (20130101) H04L 2012/4028 (20130101)
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10581893 — Modeling of attacks on cyber-physical systems

US 10581893	Warnick et al.
FUNDED BY	Department of Homeland Security (DHS) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	BRIGHAM YOUNG UNIVERSITY (Provo, Utah); Washington State University (Pullman, Washington)
ASSIGNEE(S)	Brigham Young University (BYU) (Provo, Utah); Washington State University (Pullman, Washington)
INVENTOR(S)	Sean Warnick (Provo, Utah); Sandip Roy (Pullman, Washington)
ABSTRACT	Techniques of preventing sabotage attacks in cyber-physical systems involve automatically identifying links between nodes of a graph representing cyber-physical systems as vulnerable to sabotage attacks according to a vulnerability metric for each link. The vulnerability metric used depends on the particular sabotage attack used to determine the vulnerable links. Once a computer configured to design cyber-physical systems based on vulnerability to sabotage attacks receives data representing the graph, the computer enumerates the possible links between nodes of the graph along which a sabotage attack may be performed. For each of those links, the computer computes the vulnerability metric. The computer then ranks the links according to respective values of the vulnerability metric. Based on the ranking, a designer may then perform a mitigation analysis that results in changes to the graph to reduce the vulnerability at each node accessible to a malicious actor.
FILED	Wednesday, December 06, 2017
APPL NO	15/833693
ART UNIT	2493 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 7/08 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101) Original (OR) Class H04L 63/1466 (20130101)
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10581894 — Assessing effectiveness of cybersecurity technologies

US 10581894	Zaffarano et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Siege Technologies LLC (Rome, New York)
ASSIGNEE(S)	SIEGE TECHNOLOGIES LLC (Manchester, New Hampshire)
INVENTOR(S)	Kara Zaffarano (Rome, New York); Joshua Taylor (Rome, New York); Samuel Hamilton (Falls Church, Virginia)
ABSTRACT	A method for assessing effectiveness of one or more cybersecurity technologies in a computer network includes testing each of two or more component stages of an attack model at a first computer network element twice. A first one of the tests is conducted with a first one of the cybersecurity technologies operable to protect the first computer network element, and a second one of the tests is conducted with the first cybersecurity technology not operable to protect the first computer network element. For each one of the twice-tested component stages, comparing results from the first test and the second test, wherein the comparison yields or leads to information helpful in assessing effectiveness of the first cybersecurity technology on each respective one of the twice-tested component stages at the computer network element.
FILED	Monday, April 22, 2019
APPL NO	16/390352
ART UNIT	2431 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/1433 (20130101) Original (OR) Class
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10582120 — Systems, methods, and media for providing interactive refocusing in images

US 10582120	Nayar et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Shree K. Nayar (New York, New York); Daniel Miau (Bronx, New York); Changyin Zhou (Mountain View, California)
ABSTRACT	Systems, methods, and media for providing interactive refocusing are provided, the systems comprising: a lens; an image sensor; and a processor that: causes the image sensor to capture a plurality of images over a predetermined period of time, wherein each of the plurality of images represents a scene at a different point in time; changes a depth of field between at least a pair of the plurality of images; concatenates the plurality of images to create a duration focal volume in the order in which the images were captured; computes a space-time in-focus image that represents in-focus portions from each of the plurality of images based on the duration focal volume; and computes a space-time index map that identifies an in-focus image for each location of the scene from among the plurality of images based on the duration focal volume and the space-time in-focus image.
FILED	Friday, December 14, 2018
APPL NO	16/220625
ART UNIT	2699 — Search and Capture Special Detail
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 27/0075 (20130101) G02B 27/646 (20130101) Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 2200/21 (20130101) G06T 2207/10016 (20130101) G06T 2207/10024 (20130101) G06T 2207/10148 (20130101) G06T 2207/20016 (20130101) Pictorial Communication, e.g Television H04N 5/2356 (20130101) H04N 5/23212 (20130101) H04N 5/23216 (20130101) H04N 5/23229 (20130101) Original (OR) Class
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10582181 — Panoramic vision system with parallax mitigation

US 10582181	Leiphon et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
ASSIGNEE(S)	HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
INVENTOR(S)	Ken Leiphon (Phoenix, Arizona); William Ray Hancock (Phoenix, Arizona)
ABSTRACT	A panoramic image system with parallax mitigation includes image sensors, a head tracker, a display, and a processor. Each image sensor is fixedly mounted a predetermined linear distance from a first reference axis and is disposed adjacent to at least one other image sensor and to point in a direction that is offset from its adjacent image sensor by a predetermined angle. The head tracker is configured to sense at least the angular position and movement direction of a viewer's head about a second reference axis and to supply an azimuth position signal representative thereof. The display is configured to selectively display images sensed by each of the image sensors. The processor is in operable communication with the image sensors, head tracker, and display. The processor is configured, based at least on the azimuth position signal, to command the display to display images sensed by only one image sensor.
FILED	Tuesday, March 27, 2018
APPL NO	15/936533
ART UNIT	2487 — Recording and Compression
CURRENT CPC	Pictorial Communication, e.g Television H04N 5/23238 (20130101) H04N 13/38 (20180501) H04N 13/128 (20180501) Original (OR) Class H04N 13/332 (20180501) H04N 13/371 (20180501) H04N 13/398 (20180501) H04N 2213/001 (20130101)
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10582305 — Electrostatic graphene speaker

US 10582305	Zhou et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Qin Zhou (Fremont, California); Alexander K. Zettl (Kensington, California)
ABSTRACT	This disclosure provides systems, methods, and apparatus associated with an electrostatically driven graphene speaker. In one aspect, a device includes a graphene membrane, a first frame on a first side of the graphene membrane, and a second frame on a second side of the graphene membrane. The first frame and the second frame both include substantially circular open regions that define a substantially circular portion of the graphene membrane. A first electrode is proximate the first side of the circular portion of the graphene membrane. A second electrode proximate the second side of the circular portion of the graphene membrane.
FILED	Friday, August 16, 2019
APPL NO	16/542847
ART UNIT	2651 — Videophones and Telephonic Communications
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 19/005 (20130101) Original (OR) Class H04R 29/001 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/733 (20130101)
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10582421 — Adaptive network with interconnected autonomous devices

US 10582421	Buyuktosunoglu et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Alper Buyuktosunoglu (White Plains, New York); Pradip Bose (Yorktown Heights, New York); Augusto J. Vega (Astoria, New York)
ABSTRACT	A computer program product includes a computer readable storage medium having program instructions embodied therewith. The program instructions are executable by a processor to cause the processor to perform a method that includes determining, by a first base station, that the first base station is overloaded with connections from mobile devices. Responsive to the first base station being overloaded, a status update may be received, by the first base station, from each of a plurality of base stations. A second base station may be selected, by the first base station, from among the plurality of base stations. Responsive to the first base station being overloaded, the second base station may be instructed, by the first base station, to relocate from a first position to a new position closer to the first base station. The plurality of base stations automatically relocate to load-balance connections from the plurality of mobile devices.
FILED	Thursday, April 12, 2018
APPL NO	15/951600
ART UNIT	2474 — Multiplex and VoIP
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 43/16 (20130101) Wireless Communication Networks H04W 28/08 (20130101) Original (OR) Class H04W 28/0226 (20130101)
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Department of Energy (DOE)

10576462 — Mesoporous materials and processes for preparation thereof

US 10576462	Suib et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
ASSIGNEE(S)	University of Connecticut (Farmington, Connecticut)
INVENTOR(S)	Steven L. Suib (Storrs, Connecticut); Altug Suleyman Poyraz (Willington, Connecticut); Lei Jin (Unionville, Connecticut); Chung-hao Kuo (Willington, Connecticut)
ABSTRACT	A process for preparing a mesoporous material, e.g., transition metal oxide, sulfide, selenide or telluride, Lanthanide metal oxide, sulfide, selenide or telluride, a post-transition metal oxide, sulfide, selenide or telluride and metalloid oxide, sulfide, selenide or telluride. The process comprises providing an acidic mixture comprising a metal precursor, an interface modifier, a hydrotropic or lyotropic ion precursor, and a surfactant; and heating the acidic mixture at a temperature and for a period of time sufficient to form the mesoporous material. A mesoporous material prepared by the above process. A method of controlling nano-sized wall crystallinity and mesoporosity in mesoporous materials. The method comprises providing an acidic mixture comprising a metal precursor, an interface modifier, a hydrotropic or lyotropic ion precursor, and a surfactant; and heating the acidic mixture at a temperature and for a period of time sufficient to control nano-sized wall crystallinity and mesoporosity in the mesoporous material. Mesoporous materials and a method of tuning structural properties of mesoporous materials.
FILED	Thursday, May 08, 2014
APPL NO	14/891218
ART UNIT	1788 — Miscellaneous Articles, Stock Material
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 21/066 (20130101) B01J 23/10 (20130101) B01J 23/14 (20130101) B01J 23/20 (20130101) B01J 23/24 (20130101) B01J 23/30 (20130101) B01J 23/34 (20130101) B01J 27/04 (20130101) B01J 27/14 (20130101) Original (OR) Class B01J 27/053 (20130101) B01J 27/057 (20130101) B01J 29/40 (20130101) B01J 29/045 (20130101) B01J 29/0341 (20130101) B01J 35/0013 (20130101) B01J 35/023 (20130101) B01J 35/1014 (20130101) B01J 35/1019 (20130101) B01J 35/1023 (20130101) B01J 35/1038 (20130101) B01J 35/1042 (20130101) B01J 35/1047 (20130101) B01J 35/1057 (20130101) B01J 35/1061 (20130101) B01J 37/04 (20130101) B01J 37/08 (20130101) B01J 37/10 (20130101) B01J 37/0018 (20130101) B01J 37/084 (20130101) B01J 2229/37 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/002 (20130101) C01B 19/007 (20130101) C01B 32/00 (20170801) C01B 33/12 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/0043 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 1/02 (20130101) C01G 1/12 (20130101) C01G 9/08 (20130101) C01G 11/00 (20130101) C01G 11/02 (20130101) C01G 11/006 (20130101) C01G 19/02 (20130101) C01G 25/02 (20130101) C01G 27/02 (20130101) C01G 33/00 (20130101) C01G 35/00 (20130101) C01G 37/02 (20130101) C01G 37/033 (20130101) C01G 41/00 (20130101) C01G 45/02 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/74 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) C01P 2006/12 (20130101) C01P 2006/14 (20130101) C01P 2006/16 (20130101) C01P 2006/17 (20130101) C01P 2006/37 (20130101) C01P 2006/40 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101)
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10577466 — Ordered nanoscale domains by infiltration of block copolymers

US 10577466	Darling et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UChicago Argonne, LLC (, None)
ASSIGNEE(S)	UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Seth B. Darling (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Yu-Chih Tseng (Westmont, Illinois); Qing Peng (Downers Grove, Illinois)
ABSTRACT	A method of preparing tunable inorganic patterned nanofeatures by infiltration of a block copolymer scaffold having a plurality of self-assembled periodic polymer microdomains. The method may be used sequential infiltration synthesis (SIS), related to atomic layer deposition (ALD). The method includes selecting a metal precursor that is configured to selectively react with the copolymer unit defining the microdomain but is substantially non-reactive with another polymer unit of the copolymer. A tunable inorganic features is selectively formed on the microdomain to form a hybrid organic/inorganic composite material of the metal precursor and a co-reactant. The organic component may be optionally removed to obtain an inorganic feature s with patterned nanostructures defined by the configuration of the microdomain.
FILED	Monday, October 24, 2016
APPL NO	15/332335
ART UNIT	1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/42 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/001 (20130101) Original (OR) Class Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/02 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 9/025 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0271 (20130101) H01L 51/441 (20130101) H01L 51/4213 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/166 (20130101) H01M 10/0565 (20130101) H01M 2300/0082 (20130101)
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10577511 — Stretchable hydrophobic materials and methods for making the same

US 10577511	Larimer et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Curtis J. Larimer (Richland, Washington); Raymond S. Addleman (Benton City, Washington); Michelle R. Brann (Richland, Washington); George T. Bonheyo (Sequim, Washington); Eric M. Winder (Sequim, Washington)
ABSTRACT	Hydrophobic materials, processes for their production, and uses thereof are described. The materials can be made with silica or polytetrafluoroethylene particles embedded into a liquid polymer. The hydrophobic materials are stretchable.
FILED	Thursday, January 19, 2017
APPL NO	15/410225
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Diagnosis; Surgery; Identification A61B 42/00 (20160201) A61B 42/10 (20160201) A61B 2017/00526 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/12 (20130101) B05D 5/00 (20130101) B05D 5/08 (20130101) B05D 7/02 (20130101) B05D 7/548 (20130101) B05D 2401/20 (20130101) B05D 2401/32 (20130101) B05D 2451/00 (20130101) B05D 2451/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) C08K 3/36 (20130101) C08K 3/36 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/00 (20130101) C09D 7/61 (20180101) C09D 7/62 (20180101) Original (OR) Class C09D 7/65 (20180101) C09D 107/02 (20130101) C09D 107/02 (20130101) C09D 109/04 (20130101) C09D 109/04 (20130101)
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10577518 — Aqueous dispersions, coating compositions formed with aqueous dispersions, and multi-layer coatings

US 10577518	Xu et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	PPG Industries Ohio, Inc. (Cleveland, Ohio)
ASSIGNEE(S)	PPG Industries Ohio, Inc. (Cleveland, Ohio)
INVENTOR(S)	Xiangling Xu (Pittsburgh, Pennsylvania); Hongying Zhou (Allison Park, Pennsylvania); Richard J. Sadvary (Tarentum, Pennsylvania); Shanti Swarup (Allison Park, Pennsylvania)
ABSTRACT	An aqueous dispersion includes an aqueous medium and self-crosslinkable core-shell particles dispersed in the aqueous medium. The core-shell particles include (1) a polymeric core at least partially encapsulated by (2) a polymeric shell having urethane linkages, keto and/or aldo functional groups, and hydrazide functional groups. Further, the polymeric core is covalently bonded to at least a portion of the polymeric shell.
FILED	Thursday, June 29, 2017
APPL NO	15/636687
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 222/10 (20130101) C08F 283/006 (20130101) C08F 283/008 (20130101) C08F 290/067 (20130101) Compositions of Macromolecular Compounds C08L 51/08 (20130101) C08L 2201/52 (20130101) C08L 2201/54 (20130101) C08L 2207/53 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/022 (20130101) C09D 7/61 (20180101) C09D 7/65 (20180101) C09D 7/70 (20180101) C09D 151/08 (20130101) Original (OR) Class C09D 167/00 (20130101) C09D 175/04 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 525/902 (20130101)
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10577594 — Polypeptides having arabinofuranosidase activity and polynucleotides encoding same

US 10577594	Harris et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Novozymes, Inc. (Davis, California)
ASSIGNEE(S)	Novozymes, Inc. (Davis, California)
INVENTOR(S)	Paul Vincent Harris (Carnation, Washington); Sumati Hasani (Danville, California); Fang Liu (Livermore, California)
ABSTRACT	The present invention relates to isolated polypeptides having arabinofuranosidase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding modules.
FILED	Friday, July 22, 2016
APPL NO	15/746974
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 2319/00 (20130101) C07K 2319/01 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Original (OR) Class C12N 15/52 (20130101) C12N 15/8257 (20130101) Enzymes C12Y 302/01 (20130101) C12Y 302/01055 (20130101)
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10577617 — Plants having increased biomass and methods for making the same

US 10577617	Grennan et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) Department of Agriculture (USDA)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois); The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); The Board of Regents of the University of Nebraska (Lincoln, Nebraska); The University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); The Board of Regents of the University of Nebraska (Lincoln, Nebraska); The University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S)	Aleel K. Grennan (Urbana, Illinois); Donald R. Ort (Champaign, Illinois); Stephen Patrick Moose (Urbana, Illinois); Damla D. Bilgin (San Diego, California); Thomas Clemente (Lincoln, Nebraska); Fredy Altpeter (Gainesville, Florida); Stephen P. Long (Champaign, Illinois)
ABSTRACT	The impact of plastid size change in both monocot and dicot plants has been examined. In both, when plastid size is increased there is an increase in biomass relative to the parental lines. Thus, provided herein are methods for increasing the biomass of a plant, comprising decreasing the expression of at least one plastid division protein in a plant. Optionally, the level of chlorophyll in the plant is also reduced.
FILED	Wednesday, January 13, 2016
APPL NO	14/995109
ART UNIT	1662 — Plants
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) Original (OR) Class C12N 15/8261 (20130101)
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10577622 — Polypeptides having beta-xylosidase activity and polynucleotides encoding same

US 10577622	Zhang et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Novozymes Inc. (Davis, California)
ASSIGNEE(S)	Novozymes Inc. (Davis, California)
INVENTOR(S)	Yu Zhang (Beijing, China PRC); Ye Liu (Beijing, China PRC); Junxin Duan (Beijing, China PRC); Lan Tang (Beijing, China PRC); Brett McBrayer (Sacramento, California)
ABSTRACT	The present invention relates to isolated polypeptides having beta-xylosidase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
FILED	Wednesday, August 29, 2018
APPL NO	16/115949
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/248 (20130101) C12N 9/2445 (20130101) C12N 15/1137 (20130101) C12N 15/8218 (20130101) C12N 15/8242 (20130101) Original (OR) Class C12N 15/8246 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 302/01008 (20130101) C12Y 302/01021 (20130101) C12Y 302/01037 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/17 (20130101) Y02E 50/343 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101)
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10577629 — In vitro recombination method

US 10577629	Young et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	SGI-DNA, INC. (San Diego, California)
ASSIGNEE(S)	SGI-DNA, Inc. (San Diego, California)
INVENTOR(S)	Lei Young (Gaithersburg, Maryland); Hamilton O. Smith (San Diego, California); Daniel Glenn Gibson (Carlsbad, California)
ABSTRACT	The present invention relates, e.g., to in vitro method, using isolated protein reagents, for joining two double stranded (ds) DNA molecules of interest, wherein the distal region of the first DNA molecule and the proximal region of the second DNA molecule share a region of sequence identity, comprising contacting the two DNA molecules in a reaction mixture with (a) a non-processive 5′ exonuclease; (b) a single stranded DNA binding protein (SSB) which accelerates nucleic acid annealing; (c) a non strand-displacing DNA polymerase; and (d) a ligase, under conditions effective to join the two DNA molecules to form an intact double stranded DNA molecule, in which a single copy of the region of sequence identity is retained. The method allows the joining of a number of DNA fragments, in a predetermined order and orientation, without the use of restriction enzymes.
FILED	Tuesday, December 20, 2016
APPL NO	15/385537
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/93 (20130101) C12N 9/1252 (20130101) C12N 15/10 (20130101) C12N 15/64 (20130101) C12N 15/66 (20130101) C12N 15/902 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/62 (20130101) C12Q 1/62 (20130101) C12Q 1/686 (20130101) C12Q 1/6862 (20130101) C12Q 1/6862 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) C12Q 2522/101 (20130101) C12Q 2522/101 (20130101) C12Q 2522/101 (20130101) Enzymes C12Y 207/07007 (20130101) C12Y 301/11003 (20130101) C12Y 605/01001 (20130101)
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10577633 — Enzyme scaffolds and methods of use

US 10577633	Bomble et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S)	Yannick J. Bomble (Arvada, Colorado); Michael E. Himmel (Littleton, Colorado); Jeffrey Linger (Denver, Colorado); Roman Brunecky (Arvada, Colorado); John Aikens (La Grange, Illinois)
ABSTRACT	Polypeptide scaffolds comprising enzymatic proteins are provided. The enzymatic polypeptide scaffolds comprise heterologous enzymes to form a heterologous metabolic pathway, and can be targeted to a substrate through a surface anchoring domain. The enzymatic polypeptide scaffolds leverage the high specificity and affinity protein/protein interaction between the cohesins and dockerins of microorganismal cellulosomes to form custom enzymatic arrays.
FILED	Thursday, March 23, 2017
APPL NO	15/467340
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0036 (20130101) C12N 9/1022 (20130101) C12N 11/00 (20130101) C12N 11/06 (20130101) C12N 11/18 (20130101) C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/18 (20130101) Original (OR) Class C12P 7/42 (20130101) Enzymes C12Y 101/01006 (20130101) C12Y 101/01076 (20130101) C12Y 101/01086 (20130101) C12Y 102/01 (20130101) C12Y 102/01003 (20130101) C12Y 106/03 (20130101) C12Y 106/03001 (20130101) C12Y 202/01006 (20130101)
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10577694 — Protective aluminum oxide surface coatings and low-temperature forming process for high-temperature applications

US 10577694	Choi et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Jung-Pyung Choi (Richland, Washington); Jeffry W. Stevenson (Richland, Washington)
ABSTRACT	A method of both coating a substrate with aluminum oxide and infusing the substrate with elemental aluminum is disclosed. In one example, the method includes providing a metal powder/polymer binder slurry, the slurry having a solvent, an organic binder, metal granules and a seed element, wherein the metal granules include Al; dispersing the slurry upon a Cr-containing surface; after dispersing the slurry, exposing the slurry to air and maintaining the temperature of the slurry and substrate below 110° C. to remove at least a portion of the solvent from the slurry; and, in a combined step, both exposing the binder, metal granules and substrate to air and heating the remaining slurry and substrate at a temperature less than or equal to 1000° C. to both diffuse at least a portion of the metal of the metal granules into the substrate and coat the substrate with aluminum oxide.
FILED	Wednesday, January 10, 2018
APPL NO	15/867370
ART UNIT	1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 10/18 (20130101) C23C 10/30 (20130101) C23C 10/60 (20130101) C23C 22/02 (20130101) C23C 22/82 (20130101) Original (OR) Class Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 58/14 (20130101) Methods of Steam Generation; Steam Boilers F22B 37/107 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0245 (20130101)
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10578533 — Specimen for evaluating pressure pulse cavitation in rock formations

US 10578533	Wang et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Jy-An John Wang (Oak Ridge, Tennessee); Hong Wang (Oak Ridge, Tennessee); Fei Ren (Philadelphia, Pennsylvania); Thomas S. Cox (Oak Ridge, Tennessee)
ABSTRACT	An apparatus 300 for simulating a pulsed pressure induced cavitation technique (PPCT) from a pressurized working fluid (F) provides laboratory research and development for enhanced geothermal systems (EGS), oil, and gas wells. A pump 304 is configured to deliver a pressurized working fluid (F) to a control valve 306, which produces a pulsed pressure wave in a test chamber 308. The pulsed pressure wave parameters are defined by the pump 304 pressure and control valve 306 cycle rate. When a working fluid (F) and a rock specimen 312 are included in the apparatus, the pulsed pressure wave causes cavitation to occur at the surface of the specimen 312, thus initiating an extensive network of fracturing surfaces and micro fissures, which are examined by researchers.
FILED	Wednesday, October 12, 2016
APPL NO	15/291294
ART UNIT	2861 — Printing/Measuring and Testing
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/122 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/26 (20130101) E21B 49/006 (20130101) Pipe-line Systems; Pipe-lines F17D 1/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/567 (20130101) Original (OR) Class G01N 29/2418 (20130101) G01N 33/2823 (20130101) G01N 2203/0055 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 7/18 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0391 (20150401)
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10578547 — On-chip spectroscopic sensors with optical fringe suppression

US 10578547	Green et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York); TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	William Green (Yorktown Heights, New York); Chu Cheyenne Teng (Princeton, New Jersey); Gerard Wysocki (Princeton, New Jersey); Eric Zhang (Yorktown Heights, New York)
ABSTRACT	An on-chip spectroscopic sensor includes a tunable diode laser. A laser driver for drives the tunable diode laser. An analyte test cavity receives a chemical sample and exposes the received chemical sample to light from the tunable diode laser. An optical detector detects light emerging from the analyte test cavity as a result of the laser exposure. A spectral analyzer determines a spectrum of the emerging light, matches and removes one or more known optical fringe patterns from the determined spectrum, and determines a composition or concentration of the chemical sample from the optical fringe pattern-removed spectrum.
FILED	Wednesday, March 07, 2018
APPL NO	15/914455
ART UNIT	2886 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/45 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/27 (20130101) Original (OR) Class G01N 33/0047 (20130101) G01N 2201/1211 (20130101) G01N 2201/06113 (20130101)
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10578569 — Apparatus for determining a thermal conductivity and a thermal diffusivity of a material, and related methods

US 10578569	Hurley et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)	BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho)
ASSIGNEE(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S)	David H. Hurley (Idaho Falls, Idaho); Robert S. Schley (Rigby, Idaho); Marat Khafizov (Columbus, Ohio)
ABSTRACT	A method of determining a thermal conductivity and a thermal diffusivity of a material comprises exposing a specimen comprising a substrate of a material and a metallic film over the substrate to an amplitude modulated pump laser beam comprising electromagnetic radiation having a first wavelength and a first modulation frequency to form a pump spot on the metallic film. The specimen is exposed to a probe laser beam comprising electromagnetic radiation having a second wavelength to form a probe spot on the metallic film. A phase shift between the pump laser beam and a reflected probe laser beam is measured while scanning the pump spot relative to the probe spot. A modulation frequency of the pump laser beam is changed to a second modulation frequency and the pump spot is scanned relative to the probe spot while detecting the phase shift. A phase profile of the material is measured and a continuum-based model is fit to the phase profile. Related microscopes and related methods are also disclosed.
FILED	Monday, November 07, 2016
APPL NO	15/345330
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/18 (20130101) Original (OR) Class
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10578593 — Open port sampling interface

US 10578593	Van Berkel
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Gary J. Van Berkel (Oak Ridge, Tennessee)
ABSTRACT	A system for sampling a sample material includes a probe which can have an outer probe housing with an open end. A liquid supply conduit within the housing has an outlet positioned to deliver liquid to the open end of the housing. The liquid supply conduit can be connectable to a liquid supply for delivering liquid at a first volumetric flow rate to the open end of the housing. A liquid exhaust conduit within the housing is provided for removing liquid from the open end of the housing. A liquid exhaust system can be provided for removing liquid from the liquid exhaust conduit at a second volumetric flow rate. A droplet dispenser can dispense drops of a sample or a sample-containing solvent into the open end of the housing. A sensor and a processor can be provided to monitor and maintain a liquid dome present at the open end.
FILED	Wednesday, August 08, 2018
APPL NO	16/058663
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/44 (20130101) A61B 5/443 (20130101) A61B 5/4845 (20130101) A61B 10/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/00 (20130101) G01N 1/20 (20130101) G01N 30/7233 (20130101) Original (OR) Class G01N 35/1095 (20130101) G01N 2001/028 (20130101) G01N 2001/045 (20130101) G01N 2030/027 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0404 (20130101) H01J 49/0431 (20130101)
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10578762 — Systems and methods for locating and imaging proppant in an induced fracture

US 10578762	Aldridge et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	CARBO CERAMICS INC. (Houston, Texas); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	CARBO CERAMICS, INC. (Houston, Texas); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	David F. Aldridge (Albuquerque, New Mexico); Lewis Bartel (Albuquerque, New Mexico)
ABSTRACT	Born Scattering Inversion (BSI) systems and methods are disclosed. A BSI system may be incorporated in a well system for accessing natural gas, oil and geothermal reserves in a geologic formation beneath the surface of the Earth. The BSI system may be used to generate a three-dimensional image of a proppant-filled hydraulically-induced fracture in the geologic formation. The BSI system may include computing equipment and sensors for measuring electromagnetic fields in the vicinity of the fracture before and after the fracture is generated, adjusting the parameters of a first Born approximation model of a scattered component of the surface electromagnetic fields using the measured electromagnetic fields, and generating the image of the proppant-filled fracture using the adjusted parameters.
FILED	Monday, March 26, 2018
APPL NO	15/935787
ART UNIT	2865 — Printing/Measuring and Testing
CURRENT CPC	Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/26 (20130101) G01V 3/30 (20130101) Original (OR) Class G01V 3/38 (20130101) G01V 99/00 (20130101) G01V 99/005 (20130101)
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10578763 — Modular electrode tool for improved hydraulic fracture diagnostics

US 10578763	Gabelmann et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	The Board of Regents of The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents of the University of Texas System (Austin, Texas); E-Spectrum Technologies (San Antonio, Texas)
INVENTOR(S)	Jeffrey Gabelmann (Boerne, Texas); Mark Allen Oerkfitz (San Antonio, Texas); Thomas David Hosbach (San Antonio, Texas); Mukul M. Sharma (Austin, Texas); Ali Yilmaz (Austin, Texas); Carlos Torres-Verdin (Austin, Texas)
ABSTRACT	Systems and methods for assessing physical properties of a geological formation are disclosed. The systems and methods may use electrodes that include two conductive portions separated by an isolation gap positioned along a casing in a wellbore in the formation. The electrodes may be sequentially energized to provide excitation stimulus into the formation while the remaining, non-energized electrodes may substantially simultaneously receive excitation responses to the excitation stimulus from the formation. The excitation responses may be assessed to determine one or more physical properties of fractures in the formation.
FILED	Tuesday, November 21, 2017
APPL NO	15/818911
ART UNIT	3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/267 (20130101) E21B 47/01 (20130101) E21B 47/121 (20130101) E21B 47/122 (20130101) E21B 47/124 (20130101) E21B 49/00 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/20 (20130101) G01V 3/26 (20130101) G01V 3/34 (20130101) Original (OR) Class
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10580610 — Cold cathode switching device and converter

US 10580610	Sommerer et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
ASSIGNEE(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S)	Timothy John Sommerer (Charlton, New York); Joseph Darryl Michael (Schenectady, New York); David John Smith (Clifton Park, New York); Sergey Joseph Zalubovsky (Niskayuna, New York)
ABSTRACT	A cold-cathode switching device is presented. The cold-cathode switching device includes a housing defining a chamber; an ionizable gas disposed in the chamber; and a plurality of electrodes disposed in the chamber. The plurality of electrodes includes a cathode and an anode defining a discharge gap, and wherein at least one of the cathode and anode comprises a material that is liquid at an operating temperature of the cathode or the anode.
FILED	Tuesday, May 21, 2013
APPL NO	14/776758
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 13/08 (20130101) Original (OR) Class H01J 13/52 (20130101) H01J 17/08 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/006 (20130101)
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10580614 — Compressive scanning spectroscopy

US 10580614	Stevens et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Andrew J. Stevens (Richland, Washington); Libor Kovarik (Pasco, Washington); Nigel D. Browning (Richland, Washington)
ABSTRACT	Mask-modulated spectra are incident to a sensor and are summed during a frame time. After the frame time, a compressed spectrum is read out based on the sum and decompressed to obtain spectra for some or all specimen locations. The mask-modulated spectrum that are summed are associated with different modulations produced by a common mask.
FILED	Friday, April 07, 2017
APPL NO	15/482629
ART UNIT	2881 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/28 (20130101) Original (OR) Class H01J 37/222 (20130101) H01J 37/244 (20130101) H01J 2237/221 (20130101) H01J 2237/2802 (20130101) H01J 2237/24455 (20130101) H01J 2237/24485 (20130101) H01J 2237/24578 (20130101) H01J 2237/24585 (20130101)
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10580634 — Systems and methods for relay ionization

US 10580634	Cooks et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Robert Graham Cooks (West Lafayette, Indiana); Anyin Li (West Lafayette, Indiana); Adam Hollerbach (West Lafayette, Indiana)
ABSTRACT	The invention generally relates to systems and methods for relay ionization of a sample. In certain aspects, the invention provides systems that include an ion source that generates ions, a sample emitter configured to hold a sample, and a mass spectrometer. The system is configured such that the ions generated by the ion source are directed to interact with the sample emitter, thereby causing the sample to be discharged from the sample emitter and into the mass spectrometer.
FILED	Monday, July 22, 2019
APPL NO	16/518291
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/00 (20130101) H01J 49/04 (20130101) H01J 49/165 (20130101) H01J 49/167 (20130101) H01J 49/0409 (20130101) Original (OR) Class
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10580872 — Oxide heterostructures having spatially separated electron-hole bilayers

US 10580872	Eom et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Chang-Beom Eom (Madison, Wisconsin); Hyungwoo Lee (Madison, Wisconsin)
ABSTRACT	Oxide heterostructures that form spatially separated electron-hole bilayers are provided. Also provided are electronic devices that incorporate the oxide heterostructures. The oxide heterostructure includes a base layer of SrTiO₃, a polar layer of LaAlO₂, and a non-polar layer of SrTiO₃. Within the oxide heterostructures, a two-dimensional hole gas (2DHG) is formed at the interface between the non-polar layer and the polar layer and a two-dimensional electron gas (2DEG) is formed at the interface between the polar layer and the base layer.
FILED	Tuesday, May 16, 2017
APPL NO	15/596505
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) Original (OR) Class H01L 29/778 (20130101) H01L 29/7781 (20130101) H01L 29/66969 (20130101)
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10581003 — Method for lithograghic patterning of sensitive materials

US 10581003	Melosh et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) SLAC National Accelerator Laboratory (SLAC) Federally Funded Research and Development Center (FFRDC) Operated by Stanford University (LSJU) at Menlo Park, CA
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustee of the Leland Stanford Junior Universtiy (Stanford, California)
INVENTOR(S)	Nicholas Alexander Melosh (Menlo Park, California); Matt R. Angle (Stanford, California); Mina-elraheb S. Hanna (Stanford, California); Yifan Kong (Stanford, California)
ABSTRACT	Methods for patterning highly sensitive materials, such as organic materials, organic semiconductors, biomolecular materials, and the like, with photolithographic resolution are disclosed. In some embodiments, a germanium mask (304) is formed on the surface of the sensitive material (302), thereby protecting it from subsequent processes that employ harsh chemicals that would otherwise destroy the sensitive material (302). A microlithography mask (306) is patterned on the germanium mask layer (304), after which the germanium exposed by the microlithography mask (306) is removed by dissolving it in water. After transferring the pattern of the germanium mask (304) into the sensitive material (302), the germanium and microlithography masks (304, 306) are completely removed by immersing the substrate in water, which dissolves the remaining germanium and lifts off the microlithography mask material. As a result, the only chemical to which the sensitive material (302) is exposed during the patterning process is water, thereby mitigating or avoiding damage to the material (302).
FILED	Friday, September 01, 2017
APPL NO	16/329947
ART UNIT	2895 — Semiconductors/Memory
CURRENT CPC	Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/40 (20130101) G03F 7/422 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0016 (20130101) H01L 51/0018 (20130101) H01L 51/0037 (20130101) H01L 51/0043 (20130101) H01L 51/102 (20130101) H01L 51/0541 (20130101) H01L 51/0558 (20130101) Original (OR) Class
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10581118 — Co-solvents with high coulombic efficiency in propylene carbonate based electrolytes

US 10581118	Liu et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	Gao Liu (Piedmont, California); Hui Zhao (Emeryville, California); Sang-Jae Park (Walnut Creek, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Gao Liu (Piedmont, California); Hui Zhao (Emeryville, California); Sang-Jae Park (Walnut Creek, California)
ABSTRACT	A homologous series of cyclic carbonate or propylene carbonate (PC) analog solvents with increasing length of linear alkyl substitutes were synthesized and used as co-solvents with PC for graphite based lithium ion half cells. A graphite anode reaches a capacity around 310 mAh/g in PC and its analog co-solvents with 99.95% Coulombic efficiency. Cyclic carbonate co-solvents with longer alkyl chains are able to prevent exfoliation of graphite when used as co-solvents with PC. The cyclic carbonate co-solvents of PC compete for solvation of Li ion with PC solvent, delaying PC co-intercalation. Reduction products of PC on graphite surfaces via single-electron path form a stable Solid Electrolyte Interphase (SEI), which allows the reversible cycling of graphite.
FILED	Friday, June 23, 2017
APPL NO	15/632153
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/386 (20130101) H01M 4/587 (20130101) H01M 4/5825 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 2220/20 (20130101) H01M 2300/0037 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101)
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10581481 — Communication device, spread-spectrum receiver, and related method using normalized matched filter for improving signal-to-noise ratio in harsh environments

US 10581481	Moradi et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S)	Hussein Moradi (Idaho Falls, Idaho); Jonathan D. Driggs (Salt Lake City, Utah); Arslan J. Majid (Salt Lake City, Utah); Behrouz Farhang (Salt Lake City, Utah); Taylor M. Sibbett (Cottonwood Heights, Utah)
ABSTRACT	A communication device, a method of operating a communication device, and a spread-spectrum receiver are disclosed. The method includes receiving an incoming RF signal, demodulating the incoming RF signal to generate a baseband signal, filtering the baseband signal with a normalized matched filter having filter characteristics matched to a pulse-shaping filter of the transmitter that generated the incoming RF signal, and extracting a received signal from a normalized output generated by the normalized matched filter. As a result, interferences and noise from harsh environments may be suppressed.
FILED	Tuesday, September 18, 2018
APPL NO	16/134784
ART UNIT	2631 — Digital Communications
CURRENT CPC	Transmission H04B 1/71 (20130101) H04B 1/7093 (20130101) Original (OR) Class H04B 2001/70935 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/264 (20130101)
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10582305 — Electrostatic graphene speaker

US 10582305	Zhou et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Qin Zhou (Fremont, California); Alexander K. Zettl (Kensington, California)
ABSTRACT	This disclosure provides systems, methods, and apparatus associated with an electrostatically driven graphene speaker. In one aspect, a device includes a graphene membrane, a first frame on a first side of the graphene membrane, and a second frame on a second side of the graphene membrane. The first frame and the second frame both include substantially circular open regions that define a substantially circular portion of the graphene membrane. A first electrode is proximate the first side of the circular portion of the graphene membrane. A second electrode proximate the second side of the circular portion of the graphene membrane.
FILED	Friday, August 16, 2019
APPL NO	16/542847
ART UNIT	2651 — Videophones and Telephonic Communications
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 19/005 (20130101) Original (OR) Class H04R 29/001 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/733 (20130101)
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National Science Foundation (NSF)

10576181 — Polymer nanofiber scaffolds and uses thereof

US 10576181	Pokorski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Jonathan K Pokorski (Cleveland, Ohio); Eric Baer (Cleveland, Ohio); Sieun Kim (Cleveland, Ohio); Jia Wang (Cleveland, Ohio)
ABSTRACT	A polymer nanofiber scaffold includes a plurality of melt extruded nanofibers that are chemically modified to append surface functionality to the nanofibers.
FILED	Tuesday, July 03, 2018
APPL NO	16/026228
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/02 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/26 (20130101) Original (OR) Class A61L 15/44 (20130101) A61L 27/60 (20130101) A61L 2400/12 (20130101)
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10576456 — Systems and methods of preparing stabilized lipid assemblies

US 10576456	Saavedra et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S)	Steven Scott Saavedra (Tucson, Arizona); Craig A. Aspinwall (Tucson, Arizona); Saliya N. Ratnayaka (Tucson, Arizona); Leonard Bright (Tucson, Arizona)
ABSTRACT	Direct polymerization of lipid monomers or polymer scaffolding of non-lipid monomers coupled with irradiation or redox polymerization performed at neutral pH resulted in stabilized lipid assemblies. An initiator-buffer component and NaHS03 redox mixture polymerizes reactive lipid monomers at near neutral pH conditions to preserve functionality of reconstituted membrane proteins. Improved stability of black lipid membranes (BLMs) is attained by chemical cross-linking of polymerizable, hydrophobic and commercially available non-lipid monomers partitioned into the suspended lipid membranes, and by suspending the BLMs across low surface energy apertures. Substrate apertures having low surface energy modifiers with amphiphobic properties facilitated a reproducible formation of BLMs by promoting interactions between the lipid tail and the substrate material. In addition, polymeric lipid bilayer membranes were prepared by photochemical or redox initiated polymerization of polymerizable lipid monomers, and disposed onto supporting substrates for use in chromatography columns.
FILED	Tuesday, June 30, 2015
APPL NO	15/318905
ART UNIT	1781 — Miscellaneous Articles, Stock Material
CURRENT CPC	Separation B01D 69/10 (20130101) B01D 69/105 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/286 (20130101) B01J 20/288 (20130101) B01J 20/3204 (20130101) B01J 20/3208 (20130101) B01J 20/3219 (20130101) B01J 20/3272 (20130101) Original (OR) Class B01J 20/3274 (20130101) B01J 20/3282 (20130101) B01J 20/3287 (20130101) B01J 20/3289 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/10 (20130101) B32B 3/266 (20130101) B32B 2307/20 (20130101) B32B 2307/70 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) B82Y 40/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/48 (20130101) C08F 30/08 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) G01N 2030/527 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 435/975 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24331 (20150115)
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10576514 — Devices and techniques relating to landfill gas extraction

US 10576514	Campanella et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Directorate of Technology, Innovation and Partnerships (TIP) Translational Impacts (TI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Loci Controls, Inc. (Fall River, Massachusetts)
ASSIGNEE(S)	Loci Controls, Inc. (Fall River, Massachusetts)
INVENTOR(S)	Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts)
ABSTRACT	A control system for controlling extraction of landfill gas, comprising: at least one sensor configured to measure one or more characteristics of landfill gas; at least one flow control mechanism disposed in well piping and configured to control flow of the landfill gas through the well piping; and at least one processor configured to: obtain a measured concentration of a first gas in landfill gas; determine whether the measured concentration of the first gas is either less than a first threshold concentration or greater than a second threshold concentration; when it is determined that the measured concentration is less than the first threshold concentration, control the at least one flow control mechanism to reduce flow rate of landfill gas; and when it is determined that the concentration is greater than the second threshold concentration, control the at least one flow control mechanism to increase the flow rate of landfill gas.
FILED	Friday, April 21, 2017
APPL NO	15/493174
ART UNIT	3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101)
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10576515 — Devices and techniques relating to landfill gas extraction

US 10576515	Campanella et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Directorate of Technology, Innovation and Partnerships (TIP) Translational Impacts (TI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Loci Controls, Inc. (Fall River, Massachusetts)
ASSIGNEE(S)	Loci Controls, Inc. (Fall River, Massachusetts)
INVENTOR(S)	Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts)
ABSTRACT	A control system for controlling extraction of landfill gas, the system comprising: at least one sensor; at least one flow control mechanism; and at least one processor configured to perform: obtaining a first measure of energy content in a first portion of landfill gas; controlling the at least one flow control mechanism to increase a flow rate of landfill gas; after the controlling, obtaining a second measure of energy content in a second portion of landfill gas; when it is determined that the second measure of energy content is greater than the first measure of energy content, controlling the at least one flow control mechanism to increase the flow rate of landfill gas; and when it is determined that the second measure of energy content is less than the first measure of energy content, controlling the at least one flow control mechanism to decrease the flow rate of landfill gas.
FILED	Friday, April 21, 2017
APPL NO	15/493184
ART UNIT	3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101)
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10576643 — Sensors for soft robots and soft actuators

US 10576643	Lessing et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Joshua Aaron Lessing (Cambridge, Massachusetts); George M. Whitesides (Newton, Massachusetts); Ramses V. Martinez (Somerville, Massachusetts); Dian Yang (Cambridge, Massachusetts); Bobak Mosadegh (New York, New York); Kevin C. Galloway (Somerville, Massachusetts); Firat Güder (Watertown, Massachusetts); Alok Suryavamsee Tayi (Somerville, Massachusetts)
ABSTRACT	A soft robotic device with one or more sensors is described. The sensor may be embedded in the soft body of the soft robotic device, attached to the soft body of the soft robotic device, or otherwise linked to the soft body of the soft robotic device.
FILED	Friday, August 21, 2015
APPL NO	15/503549
ART UNIT	3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) B25J 13/085 (20130101) B25J 13/087 (20130101) B25J 13/088 (20130101) B25J 15/0009 (20130101) B25J 15/12 (20130101) B25J 18/06 (20130101) Original (OR) Class
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10576701 — Production of composite parts

US 10576701	Calisch et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Sam Calisch (Cambridge, Massachusetts); Neil Gershenfeld (Cambridge, Massachusetts); Spencer Wilson (Cambridge, Massachusetts)
ABSTRACT	A process for producing a composite part includes (a) applying a loose carbon filament to a receiving portion of a first mold piece; (b) reversibly coupling the first mold piece with at least a second mold piece to form a first mold layer, wherein an interior region of the first mold layer includes a pocket configured to receive a curable resin, the pocket having a shape of the composite part; (c) infusing the curable resin into the pocket; and (d) curing the resin to form the composite part.
FILED	Monday, December 07, 2015
APPL NO	14/960825
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/32 (20130101) B29C 70/48 (20130101) Original (OR) Class B29C 70/382 (20130101) B29C 70/541 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) B29K 2105/10 (20130101) B29K 2307/04 (20130101) B29K 2823/065 (20130101)
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10577652 — Massive parallel method for decoding DNA and RNA

US 10577652	Ju et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Jingyue Ju (Englewood Cliffs, New Jersey); Zengmin Li (Flushing, New York); John Robert Edwards (St. Louis, Missouri); Yasuhiro Itagaki (New York, New York)
ABSTRACT	This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotide analogues which comprise unique labels attached to the nucleotide analogue through a cleavable linker, and a cleavable chemical group to cap the —OH group at the 3′-position of the deoxyribose.
FILED	Monday, November 26, 2018
APPL NO	16/200571
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/11 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) C07H 19/14 (20130101) C07H 21/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6872 (20130101) C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/117 (20130101) C12Q 2525/186 (20130101) C12Q 2525/186 (20130101) C12Q 2535/101 (20130101) C12Q 2535/101 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2563/107 (20130101) C12Q 2563/107 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/00 (20130101)
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10578615 — Low resource method and device for detecting analytes

US 10578615	Haselton et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	Rick Haselton (Nashville, Tennessee); David Wright (Nashville, Tennessee); Nick Adams (Nashville, Tennessee); Keersten Ricks (Nashville, Tennessee)
ABSTRACT	Systems and methods are described for isolation, separation and detection of a molecular species using a low resource device for processing of samples. Methods include isolation, separation and detection of whole cells.
FILED	Wednesday, April 08, 2015
APPL NO	15/302553
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 9/527 (20130101) B01L 2200/0668 (20130101) B01L 2300/087 (20130101) B01L 2300/0672 (20130101) B01L 2300/0867 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/558 (20130101) Original (OR) Class G01N 33/54326 (20130101) G01N 33/54333 (20130101) G01N 35/0098 (20130101)
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10579166 — Pointer acceleration system modeling

US 10579166	Malisoff et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Michael Malisoff (Baton Rouge, Louisiana); Fumin Zhang (Atlanta, Georgia); Jesse Paul Varnell (Atlanta, Georgia)
ABSTRACT	The present disclosure describes systems, methods, and apparatuses utilizing pointer acceleration system modeling. In one exemplary method, among others, such a method obtains, a closed loop pointer acceleration system model, in which the closed loop pointer acceleration system model is based on (1) a model describing user pointing motions integrated with (2) a model of pointer acceleration motions under operational conditions; obtains values for system parameters that include pointer acceleration profile parameters and operational condition parameters; and determines a set of pointer trajectories for a given acceleration profile having the pointer acceleration profile parameters and operational condition parameters.
FILED	Thursday, April 05, 2018
APPL NO	15/945895
ART UNIT	2692 — Selective Visual Display Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/038 (20130101) Original (OR) Class G06F 3/03543 (20130101) G06F 3/03547 (20130101) G06F 3/04847 (20130101)
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10579207 — Manipulating virtual environment using non-instrumented physical object

US 10579207	Piya et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Cecil Piya (West Lafayette, Indiana); Vinayak Raman Krishnamurthy (West Lafayette, Indiana); Karthik Ramani (West Lafayette, Indiana)
ABSTRACT	A method of manipulating a three-dimensional image file including a virtual object includes obtaining image information in a processing device of a non-instrumented physical object manipulated by a user, such image information including movement information; and causing virtual movement of the virtual object based on the movement information. A method of shaping a virtual object includes obtaining image information including movement information; and determining a shape of the virtual object based on the movement information. A method of modifying a virtual object includes obtaining image information including movement information; and altering a virtual surface appearance of at least a part of the virtual object based on the movement information. Systems and computer-readable media are also described.
FILED	Thursday, May 14, 2015
APPL NO	14/712695
ART UNIT	2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/04815 (20130101) Original (OR) Class
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10579495 — Systems and methods for transmitting data using encoder cooperation in the presence of state information

US 10579495	Noorzad et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	California Institute of Technology (Pasadena, California); The Research Foundation for the State University of New York (Amherst, New York)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California); The Research Foundation for the State University of New York (Amherst, New York)
INVENTOR(S)	Parham Noorzad (San Diego, California); Michelle Effros (San Marino, California); Michael Langberg (Clarence, New York)
ABSTRACT	Systems and methods for utilizing cooperation facilitators to achieve joint message and network state cooperation in accordance with various embodiments of the invention are disclosed. One embodiment of the invention includes: a plurality of transmitters; a receiver that has access to at least partial network state information and that includes a decoder configured to decode signals received via a multiple terminal channel from the plurality of transmitters using the at least partial network state information; and a cooperation facilitator. In addition, at least some of the plurality of transmitters are configured to transmit message information to the cooperation facilitator and the cooperation facilitator is configured to generate cooperation parameters based upon the message information and the manner in which state information is utilized by the receiver to decode signals received via the multiple terminal channel. In addition, the cooperation facilitator is configured to transmit cooperation parameters to the plurality of transmitters that select codewords based at least in part upon the received cooperation parameters.
FILED	Friday, May 18, 2018
APPL NO	15/984161
ART UNIT	2631 — Digital Communications
CURRENT CPC	Electric Digital Data Processing G06F 11/3006 (20130101) G06F 11/3452 (20130101) G06F 11/3466 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 13/02 (20130101)
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10580605 — Very low power microelectromechanical devices for the internet of everything

US 10580605	Tabib-Azar
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Massood Tabib-Azar (Salt Lake City, Utah)
ABSTRACT	A microelectromechanical device is disclosed and described. The microelectromechanical device can include a base having a raised support structure. The microelectromechanical device can also include a biasing electrode supported by the base. The microelectromechanical device can further include a displacement member supported by the raised support structure. The displacement member can have a movable portion extending from the raised support structure and spaced from the biasing electrode by a gap. The movable portion can be movable relative to the base by deflection of the displacement member. The displacement member can also have a piezoelectric material associated with the movable portion. In addition, the microelectromechanical device can include a voltage source electrically coupled to the piezoelectric material and the biasing electrode. The voltage source can apply a biasing voltage to the piezoelectric material and the biasing electrode to cause deflection of the displacement member toward the biasing electrode, thereby reducing the gap between the movable portion and the biasing electrode. Further deflection of the displacement member can cause an increase in voltage across the piezoelectric material and the biasing electrode sufficient to pull the movable portion into contact with the biasing electrode.
FILED	Wednesday, November 23, 2016
APPL NO	15/360508
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/0802 (20130101) G01P 2015/0828 (20130101) G01P 2015/0831 (20130101) Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 57/00 (20130101) Original (OR) Class H01H 59/0009 (20130101) H01H 2057/006 (20130101) H01H 2059/0072 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/1132 (20130101) H01L 41/1136 (20130101) Electric Machines Not Otherwise Provided for H02N 2/186 (20130101) H02N 2/188 (20130101)
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10581062 — Nanocubic Co₃O₄/few-layer graphene composites and related anode components

US 10581062	Wu et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Jinsong Wu (Wilmette, Illinois); Junming Xu (Hangzhou, China PRC); Vinayak P. Dravid (Glenview, Illinois)
ABSTRACT	Co₃O₄nanocubes as can be homogeneously assembled on a few-layer graphene sheet, such a composite as can be used in conjunction with an anode and incorporated into a high energy lithium-ion battery.
FILED	Thursday, January 14, 2016
APPL NO	14/996013
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/049 (20130101) H01M 4/131 (20130101) Original (OR) Class H01M 4/0471 (20130101) H01M 4/523 (20130101) H01M 4/625 (20130101) H01M 4/1391 (20130101)
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10581085 — Perovskite compounds for stable, high activity solid oxide fuel cell cathodes and other applications

US 10581085	Jacobs et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Office of Cyberinfrastructure (OCI)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Ryan Matthew Jacobs (Madison, Wisconsin); Dane Morgan (Middleton, Wisconsin)
ABSTRACT	Solid oxide fuel cells (SOFCs) are provided. A SOFC may comprise a cathode, an anode, and a solid oxide electrolyte between the anode and the cathode, wherein the cathode comprises a perovskite compound. The perovskite compound may be characterized by a log k* value which is less negative than about −6.0 cm/s; an energy above the convex hull of less than about 40 meV/(formula unit); a bandgap of about 0 and a charge transfer gap of about 0.
FILED	Tuesday, December 20, 2016
APPL NO	15/384482
ART UNIT	1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9033 (20130101) Original (OR) Class H01M 2004/8689 (20130101) H01M 2008/1293 (20130101)
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10581173 — On-body, inward-facing antennas

US 10581173	Grady et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Michael Dante Grady (Smyrna, Georgia); Thomas McCrea Weller (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Michael Dante Grady (Smyrna, Georgia); Thomas McCrea Weller (Tampa, Florida)
ABSTRACT	In some embodiments, an antenna includes a dielectric substrate having a first surface and a second surface opposite to the first surface, a planar central antenna element provided on the first surface, and a planar electromagnetic bandgap structure provided on the first surface and surrounding the central antenna element.
FILED	Tuesday, April 03, 2018
APPL NO	15/943986
ART UNIT	3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/22 (20130101) H01Q 1/38 (20130101) H01Q 15/006 (20130101) Original (OR) Class
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10581606 — Secure system for coupling wearable devices to computerized devices with displays

US 10581606	Liang et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S)	THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S)	Xiaohui Liang (West Lebanon, New Hampshire); Tianlong Yun (Lebanon, New Hampshire); Ronald Peterson (Brattleboro, Vermont); David Kotz (Lyme, New Hampshire)
ABSTRACT	A system has a first electronic device with optical sensor, digital radio transceiver, and processor with firmware; this device is typically portable or wearable. The system also has a computerized device with a display, a second digital radio transceiver, and a second processor with firmware. The first and computerized devices are configured to set up a digital radio link when in radio range. The second processor uses a spot on the display to optically transmit a digital message including a secret such as an encryption key or subkey and/or an authentication code adapted for authenticating an encrypting the radio link. The first device receives the digital message via its optical sensor, and uses the digital message to validate and establish encryption on the radio link. In embodiments, the system determines a location of the first device on the display and positions the transmission spot at the determined location.
FILED	Tuesday, August 18, 2015
APPL NO	15/504991
ART UNIT	2492 — Cryptography and Security
CURRENT CPC	Personal Adornments, e.g Jewellery; Coins A44C 5/0007 (20130101) Diagnosis; Surgery; Identification A61B 5/0017 (20130101) Electronic Time-pieces G04G 21/04 (20130101) Electric Digital Data Processing G06F 3/1454 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/14 (20130101) H04L 9/30 (20130101) H04L 9/0618 (20130101) H04L 9/3226 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10582305 — Electrostatic graphene speaker

US 10582305	Zhou et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Qin Zhou (Fremont, California); Alexander K. Zettl (Kensington, California)
ABSTRACT	This disclosure provides systems, methods, and apparatus associated with an electrostatically driven graphene speaker. In one aspect, a device includes a graphene membrane, a first frame on a first side of the graphene membrane, and a second frame on a second side of the graphene membrane. The first frame and the second frame both include substantially circular open regions that define a substantially circular portion of the graphene membrane. A first electrode is proximate the first side of the circular portion of the graphene membrane. A second electrode proximate the second side of the circular portion of the graphene membrane.
FILED	Friday, August 16, 2019
APPL NO	16/542847
ART UNIT	2651 — Videophones and Telephonic Communications
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 19/005 (20130101) Original (OR) Class H04R 29/001 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/733 (20130101)
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National Aeronautics and Space Administration (NASA)

10577473 — Sulfur-containing organic-inorganic hybrid gel compositions and aerogels

US 10577473	Evans et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	ASPEN AEROGELS, INC. (Northborough, Massachusetts)
ASSIGNEE(S)	Aspen Aerogels, Inc. (Northborough, Massachusetts)
INVENTOR(S)	Owen R Evans (Chelmsford, Massachusetts); Wenting Dong (Marlborough, Massachusetts); Kiranmayi Deshpande (Lake Forest, California)
ABSTRACT	Methods and materials are described for preparing organic-inorganic hybrid gel compositions where a sulfur-containing cross-linking agent covalently links the organic and inorganic components. The gel compositions are further dried to provide porous gel compositions and aerogels. The mechanical and thermal properties of the dried gel compositions are also disclosed.
FILED	Thursday, June 15, 2017
APPL NO	15/623814
ART UNIT	1768 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0065 (20130101) B01J 13/0091 (20130101) Treatment or Chemical Modification of Rubbers C08C 19/25 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/28 (20130101) Original (OR) Class C08J 9/0085 (20130101) C08J 2347/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/548 (20130101) C08K 7/02 (20130101)
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10578480 — Multi-probe system for measuring height of fluid in pipes with steady-state and turbulent flow conditions

US 10578480	Bar-Cohen et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Jet Propulsion Laboratory (JPL) Federally Funded Research and Development Center (FFRDC) Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Yoseph Bar-Cohen (Pasadena, California); Shyh-Shiuh Lih (Pasadena, California); Hyeong Jae Lee (Pasadena, California); Mircea Badescu (Pasadena, California)
ABSTRACT	A multi-probe system for real-time measurement of a fluid level in a pipe with steady-state and turbulent flow conditions is presented. The multi-probe system includes a plurality of multiplexed transducers attached in a non-destructive fashion to walls of the pipe. Multiplexing of the transducers activate and deactivate the transducers in sequence to generate independent pairs of transmit and receive wave signals through the pipe. Each transmit and receive signal pair can be used to independently establish a time-of-flight from the transducer and back to the transducer as reflected by a surface of the fluid. The transducers can be arranged as longitudinal and/or circumferential arrays on the walls of the pipe. An algorithm that determines the time-of-flight eliminates received signals having an energy level lower than or equal to a predefined minimum energy level and eliminates any time-of-flight that is shorter than a minimum threshold time.
FILED	Thursday, April 19, 2018
APPL NO	15/957495
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/2962 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2291/011 (20130101) G01N 2291/044 (20130101) G01N 2291/051 (20130101) G01N 2291/105 (20130101) G01N 2291/106 (20130101) G01N 2291/02425 (20130101) G01N 2291/02836 (20130101)
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10578528 — Compression test fixture and method therefor

US 10578528	Schaefer et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Contracting Command (ACC) National Aeronautics and Space Administration (NASA)
APPLICANT(S)	THE BOEING COMPANY (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Joseph D. Schaefer (St. Louis, Missouri); Brian P. Justusson (St. Peters, Missouri); Brian Kasperson (Seattle, Washington); David R. Barbee (St. Louis, Missouri)
ABSTRACT	A compression test fixture including a first specimen engagement member having a first channel, the first channel having a first depth; a second specimen engagement member having a second channel having a second depth that is different than the first depth; and at least one coupling member engaged to both the first specimen engagement member and the second specimen engagement member such that a gap is defined between the first specimen engagement member and the second specimen engagement member, where the first channel and the second channel support the test specimen within the gap such that at least one opposing major surface of the test specimen is visible within the gap.
FILED	Thursday, March 02, 2017
APPL NO	15/447245
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/02 (20130101) G01N 3/08 (20130101) Original (OR) Class G01N 33/00 (20130101) G01N 2033/0003 (20130101)
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10578538 — Multiple beam and convergent light illumination crossed-beam imaging

US 10578538	Bachalo et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	ARTIUM TECHNOLOGIES, INC. (Sunnyvale, California)
ASSIGNEE(S)	ARTIUM TECHNOLOGIES, INC. (Sunnyvale, California)
INVENTOR(S)	William D. Bachalo (Los Altos Hills, California); Gregory A. Payne (Richland, Washington); Khalid Ibrahim (Hatfield, Pennsylvania); Michael J. Fidrich (San Jose, California)
ABSTRACT	Methods and apparatuses to image particles are described. A plurality of illuminating light beams propagating on multiple optical paths through a particle field are generated. The plurality of illuminating light beams converge at a measurement volume. A shadow image of a particle passing through a portion of the measurement volume at a focal plane of a digital camera is imaged. Shadow images of other particles in the particle field are removed using the plurality of illuminating light beams.
FILED	Wednesday, February 17, 2016
APPL NO	15/552263
ART UNIT	2877 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/12 (20130101) G01N 15/0205 (20130101) G01N 15/0211 (20130101) G01N 15/0227 (20130101) Original (OR) Class G01N 2015/03 (20130101) G01N 2015/025 (20130101) Image Data Processing or Generation, in General G06T 7/60 (20130101) G06T 7/571 (20170101) G06T 7/593 (20170101)
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10578808 — Fiber optic rotary joint for use in an optical energy transfer and conversion system

US 10578808	Stone et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	Piedra-Sombra Corporation, Inc. (Del Valle, Texas)
ASSIGNEE(S)	Stone Aerospace, Inc. (Del Valle, Texas)
INVENTOR(S)	William C. Stone (Del Valle, Texas); Bartholomew P. Hogan (Rockville, Maryland)
ABSTRACT	A fiber optic rotary joint for use in an optical power transfer system. The fiber optic rotary joint comprising a first housing element and a second housing element rotatable with respect to the first housing element. The first and second housing elements define a chamber. Optical connectors are disposed through the housing elements and have a beam expansion block positioned in the chamber. A laser is optically connected with the fiber optic rotary joint and transmits optical energy therethrough. Collimating optics aligned with the beam expansion blocks are orientated to direct the received optical energy to a position. The optical connectors and housing elements define a continuous coolant communication path with a coolant inlet and outlet. A rotary water coupling traverses through the housing elements. In an alternative embodiment, the fiber optic rotary joint also contains an actively cooled mirror positioned optically between the collimating optics.
FILED	Wednesday, May 27, 2015
APPL NO	14/723161
ART UNIT	2883 — Optics
CURRENT CPC	Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/00 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 41/0085 (20130101) E21B 47/123 (20130101) Optical Elements, Systems, or Apparatus G02B 6/3604 (20130101) Original (OR) Class G02B 6/4268 (20130101) G02B 6/4296 (20130101) G02B 6/4415 (20130101) G02B 6/4436 (20130101) G02B 6/4458 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/30 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 50/30 (20160201) H02J 50/90 (20160201)
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10579586 — Distributed hash object archive system

US 10579586	Golpayegani et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S)	Navid Golpayegani (Greenbelt, Maryland); Curt A. Tilmes (Bel Air, Maryland); Damon N. Earp (Lanham, Maryland); Jihad S. Ashkar (Lanham, Maryland)
ABSTRACT	A method of managing objects in an archive system includes assigning a number of addresses to each of a plurality of nodes, dividing an object into a sequence of blocks, uniformly distributing the sequence of blocks across the plurality of nodes by, calculating a hash value of a unique identifier of the object to be used as an address for a first block in the sequence, storing the first block at a node to which the address is assigned, for each subsequent block in the sequence, calculating a subsequent address from a hash value of the address of an immediately previous block in the sequence and storing the subsequent block at a node to which the calculated subsequent address is assigned, iteratively calculating a hash value of the hash value of the subsequent address if the calculated subsequent address is assigned to a node where a previous block is stored, and storing the subsequent block at a node to which an address corresponding to the iteratively calculated hash value is assigned.
FILED	Wednesday, August 08, 2018
APPL NO	16/058383
ART UNIT	2133 — Memory Access and Control
CURRENT CPC	Electric Digital Data Processing G06F 16/113 (20190101) Original (OR) Class G06F 16/122 (20190101) G06F 16/9014 (20190101)
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10580296 — Advanced threat warning for autonomous vehicles

US 10580296	Pedersen et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Nissan North America, Inc. (Franklin, Tennessee); United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	Nissan North America, Inc. (Franklin, Tennessee); United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S)	Liam Pedersen (San Francisco, California); Maarten Sierhuis (San Francisco, California); Hans Utz (Campbell, California); Mauro Della Penna (San Francisco, California); Terrence Fong (Moffett Field, California); Mark Allan (Campbell, California); Maria Bualat (San Jose, California); Eric Schafer (Kentfield, California)
ABSTRACT	Methods, apparatuses, systems, and non-transitory computer readable storage media for generating risk indicators are described. The disclosed technology includes determining a vehicle route of a vehicle and external object routes of external objects. The vehicle route is determined using vehicle route data including a vehicle location and a vehicle destination. The external object routes are determined using external object route data including external object locations and external object destinations. Based on a comparison of the vehicle route data and the external object route data, external object routes that satisfy a proximity criterion are determined. Risk data for the vehicle is generated based on a vehicle state of the vehicle and external object states of the external objects corresponding to the external object routes that satisfy the proximity criterion. In response to determining that the risk data satisfies a risk criterion, at least one risk indicator is generated.
FILED	Wednesday, December 06, 2017
APPL NO	16/461200
ART UNIT	3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 2550/14 (20130101) B60W 2550/20 (20130101) B60W 2550/408 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3461 (20130101) G01C 21/3492 (20130101) G01C 21/3691 (20130101) G01C 21/3697 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0276 (20130101) G05D 2201/0213 (20130101) Traffic Control Systems G08G 1/0133 (20130101) G08G 1/163 (20130101) G08G 1/166 (20130101) G08G 1/0962 (20130101) G08G 1/0967 (20130101) Original (OR) Class G08G 1/096775 (20130101) G08G 1/096791 (20130101)
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10580633 — Systems and methods for conducting neutral loss scans in a single ion trap

US 10580633	Cooks et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Robert Graham Cooks (West Lafayette, Indiana); Dalton Snyder (West Lafayette, Indiana)
ABSTRACT	The invention generally relates to systems and methods for conducting neutral loss scans in a single ion trap. In certain aspects, the invention provides systems that include a mass spectrometer having a single ion trap, and a central processing unit (CPU), and storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to apply a scan function that excites a precursor ion, rejects the precursor ion after its excitation, and ejects a product ion in the single ion trap.
FILED	Monday, May 21, 2018
APPL NO	15/985188
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/0036 (20130101) Original (OR) Class H01J 49/0081 (20130101) H01J 49/422 (20130101) H01J 49/429 (20130101)
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10580636 — Ultrahigh resolution mass spectrometry using an electrostatic ion bottle with coupling to a quadrupole ion trap

US 10580636	Chutjian et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Jet Propulsion Laboratory (JPL) Federally Funded Research and Development Center (FFRDC) Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Ara Chutjian (La Crescenta, California); John A. MacAskill (Denver, Colorado)
ABSTRACT	An apparatus for measuring mass of one or more ions, the apparatus including an ion trap coupled to an electrostatic ion bottle (EIB).
FILED	Thursday, August 11, 2016
APPL NO	15/234848
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/424 (20130101) H01J 49/4245 (20130101) Original (OR) Class
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10580706 — Thin-film fabrication system employing mechanical stress measurement

US 10580706	Broadway
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	United States of America as Represented by NASA (Washington, District of Columbia)
ASSIGNEE(S)	United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S)	David M. Broadway (Lacey's Spring, Alabama)
ABSTRACT	A system deposits a film on a substrate while determining mechanical stress experienced by the film. A substrate is provided in a deposition chamber. A support disposed in the chamber supports a circular portion of the substrate with a first surface of the substrate facing a deposition source and a second surface being reflective. An optical displacement sensor is positioned in the deposition chamber in a spaced-apart relationship with respect to a portion of the substrate's second surface located at approximately the center of the circular portion of the substrate. When the deposition source deposits a film on the first surface, a displacement of the substrate is measured using the optical displacement sensor. A processor is programmed to use the substrate displacement to determine a radius of curvature of the substrate, and to use the radius of curvature to determine mechanical stress experienced by the film during deposition.
FILED	Monday, February 06, 2017
APPL NO	15/425740
ART UNIT	1718 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/50 (20130101) C23C 14/52 (20130101) C23C 14/5806 (20130101) C23C 16/44 (20130101) C23C 16/56 (20130101) C23C 16/458 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/16 (20130101) G01B 11/255 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 22/12 (20130101) Original (OR) Class
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10581342 — Three-level two-stage decoupled active NPC converter

US 10581342	Zhang et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Glenn Research Center (GLENN)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Di Zhang (Niskayuna, New York); Jiangbiao He (Niskayuna, New York); Sachin Madhusoodhanan (San Jose, California)
ABSTRACT	A system includes a voltage converter and a controller for controlling the operation of the voltage converter. The voltage converter includes a plurality of legs, wherein each leg includes a first and a second set of silicon (Si)-based power devices. The first set of Si-based power devices includes a first and second Si-based power devices connected to each other at a first interconnection node and the second set of Si-based power devices includes a third and fourth Si-based power devices connected to each other at a second interconnection node. The first and second set of Si-based power devices are coupled across a first and second DC voltage sources respectively. A first set of Silicon-Carbide (SiC) based power devices is coupled across the first and second interconnection nodes. The system also includes a snubber capacitor connected across the first and the second interconnection nodes.
FILED	Thursday, May 31, 2018
APPL NO	15/993945
ART UNIT	2838 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/16 (20130101) H01L 29/1608 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/34 (20130101) H02M 7/487 (20130101) Original (OR) Class H02M 7/5395 (20130101) H02M 2001/0054 (20130101) H02M 2001/346 (20130101)
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10581345 — Magnetic shape memory alloy actuator

US 10581345	Patel
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S)	Umeshkumar D. Patel (Herndon, Virginia)
ABSTRACT	The present invention relates to an actuator based on a magnetic shape memory alloy (MSMA), a new family of crystalline materials which exhibit strain deformation >10% when subjected to a magnetic field. Electromagnetic fields can be applied with very short response times, making MSMA-based actuators kHz capable. These materials have the unique property of retaining their strained state when the driving field is removed, making them unique in the world of shape memory materials, and desirable as an actuator material as they will maintain position when powered off.
FILED	Wednesday, September 20, 2017
APPL NO	15/710308
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/065 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/18 (20130101) G01B 7/24 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/12 (20130101) H01L 41/20 (20130101) Electric Machines Not Otherwise Provided for H02N 2/02 (20130101) Original (OR) Class
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10581355 — Double-fed induction linear oscillating alternator

US 10581355	Dyson
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	United States of Americas as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Rodger W. Dyson (Elyria, Ohio)
ABSTRACT	A double-fed oscillating linear alternator is provided that includes two concentric Halbach type arrays, one stationary and one movable, that do not require magnets or iron laminations to create a strong magnetic field between the two arrays where the movable array oscillates in a linear motion with respect to the stationary array. The two arrays are manufactured from magnet-less and iron-less conductive material using additive manufacturing techniques.
FILED	Friday, December 16, 2016
APPL NO	15/381801
ART UNIT	2831 — Electrical Circuits and Systems
CURRENT CPC	Dynamo-electric Machines H02K 35/00 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 9/007 (20130101) Original (OR) Class H02P 2103/20 (20150115)
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10581525 — Method and apparatus for omnidirectional optical communication

US 10581525	Velazco
FUNDED BY	National Aeronautics and Space Administration (NASA) Jet Propulsion Laboratory (JPL) Federally Funded Research and Development Center (FFRDC) Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Jose E Velazco (Pasadena, California)
ABSTRACT	An omnidirectional optical communication system. The omnidirectional optical communication system includes a multifaceted structure, a laser transmitter with a steerable mechanism, an optical detector receiver, and an angle-of-arrival system. In one aspect, the laser transmitter with a steerable mechanism, the optical detector receiver, and the angle-of-arrival system are housed in within the multifaceted structure, which enables omnidirectional optical communication. In another aspect, the omnidirectional optical communication system is used in a spacecraft for inter-spacecraft omnidirectional optical communication. In yet another aspect, the omnidirectional optical communication system is used in terrestrial applications for gigabit communications in WiFi, inter smartphones, internet of things and smart cities. In yet another aspect, the omnidirectional optical communication system further includes a global positioning system.
FILED	Wednesday, December 12, 2018
APPL NO	16/218394
ART UNIT	2636 — Optical Communications
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/782 (20130101) G01S 19/13 (20130101) Optical Elements, Systems, or Apparatus G02B 26/0833 (20130101) Transmission H04B 7/18502 (20130101) H04B 10/27 (20130101) H04B 10/66 (20130101) H04B 10/118 (20130101) Original (OR) Class H04B 10/503 (20130101)
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Department of Agriculture (USDA)

10575485 — Wheat plants having increased resistance to imidazolinone herbicides

US 10575485	Bowran et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The Department of Agriculture, Western Australia (Western Australia, Australia)
ASSIGNEE(S)	Western Australian Agriculture Authority (South Perth, Australia)
INVENTOR(S)	David Bowran (Sawyers Valley, Australia); Iain Barclay (Shelley, Australia); Kevin F. Jose (Greenwood, Australia)
ABSTRACT	The present invention is directed to plants having increased resistance to an imidazolinone herbicide. More particularly, the present invention includes wheat plants and triticale plants containing at least one IMI nucleic acid such as an imidazolinone resistant Brookton BR-8 or Krichauff K-42 cultivar. The present invention also includes seeds produced by these wheat plants and triticale plants and methods of controlling weeds in the vicinity of these wheat plants.
FILED	Thursday, June 25, 2015
APPL NO	14/750376
ART UNIT	1663 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 5/10 (20130101) A01H 6/4678 (20180501) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1022 (20130101) C12N 15/8274 (20130101)
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10575517 — Pollen field conditioning and preservation method

US 10575517	Cope et al.
FUNDED BY	Small Business Administration (SBA) Small Business Innovation Research (SBIR) Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Accelerated Ag Technologies, LLC (Ankeny, Iowa)
ASSIGNEE(S)	Accelerated Ag Technologies, LLC (Ankeny, Iowa)
INVENTOR(S)	Jason Cope (Ankeny, Iowa); George Singletary (Ankeny, Iowa); Todd Krone (Johnston, Iowa); Sara Katherine Etter (Mitchellville, Iowa)
ABSTRACT	Described are methods of preserving pollen, which may be subsequently stored. A method of the present invention includes collecting fresh pollen and introducing the pollen to a controlled environment which regulates pollen moisture content. The controlled environment may have a temperature ranging from about −10-10° C.; an adjustable and programmable relative humidity; a continuous, adjustable positive or negative air flow; and a flow of one or more continuously refreshed, selected gases which displace oxygen. In another embodiment of the method, the controlled environment may have a relative humidity from about 50-100%; a temperature from about −10-10° C.; and air pressure from about 15-150 kPa. In all embodiments of the method, an optional field conditioning step may be performed. The field conditioning step may include subjecting the pollen to an environment controlled for relative humidity, temperature, and air pressure such that the initial pollen moisture content may be adjusted to a target moisture content.
FILED	Thursday, April 13, 2017
APPL NO	15/486737
ART UNIT	1662 — Plants
CURRENT CPC	Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 7/00 (20130101) New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/02 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 3/00 (20130101) Original (OR) Class
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10576140 — Cholera toxin chimera and its use as a staph vaccine

US 10576140	Tinker
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Institute of General Medical Sciences (NIGMS) IDeA Networks of Biomedical Research Excellence (INBRE) Department of Agriculture (USDA)
APPLICANT(S)	Boise State University (Boise, Idaho)
ASSIGNEE(S)	Boise State University (Boise, Idaho)
INVENTOR(S)	Juliette Tinker (Eagle, Idaho)
ABSTRACT	The present invention relates to chimeric protein vaccines and methods of use thereof in the treatment of Staphylococcus aureus. One embodiment of the present invention provides a method of generating an immune response in a mammal, that includes administering to the mammal, a composition having a chimeric protein having at least one of: a portion of a cholera toxin, a portion of a heat-labile toxin, and a portion of a shiga toxin; and an antigen having at least one of: an antigenic material from S. aureus and an antigenic material from a S. aureus-specific polypeptide.
FILED	Wednesday, July 03, 2019
APPL NO	16/502675
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/085 (20130101) Original (OR) Class A61K 39/107 (20130101) A61K 2039/575 (20130101) A61K 2039/6037 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/25 (20130101) C07K 14/28 (20130101) C07K 14/31 (20130101) C07K 14/245 (20130101) C07K 2319/00 (20130101)
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10577617 — Plants having increased biomass and methods for making the same

US 10577617	Grennan et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) Department of Agriculture (USDA)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois); The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); The Board of Regents of the University of Nebraska (Lincoln, Nebraska); The University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); The Board of Regents of the University of Nebraska (Lincoln, Nebraska); The University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S)	Aleel K. Grennan (Urbana, Illinois); Donald R. Ort (Champaign, Illinois); Stephen Patrick Moose (Urbana, Illinois); Damla D. Bilgin (San Diego, California); Thomas Clemente (Lincoln, Nebraska); Fredy Altpeter (Gainesville, Florida); Stephen P. Long (Champaign, Illinois)
ABSTRACT	The impact of plastid size change in both monocot and dicot plants has been examined. In both, when plastid size is increased there is an increase in biomass relative to the parental lines. Thus, provided herein are methods for increasing the biomass of a plant, comprising decreasing the expression of at least one plastid division protein in a plant. Optionally, the level of chlorophyll in the plant is also reduced.
FILED	Wednesday, January 13, 2016
APPL NO	14/995109
ART UNIT	1662 — Plants
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) Original (OR) Class C12N 15/8261 (20130101)
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10577667 — Systems and methods for microbial toxin detection

US 10577667	Rasooly et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Rueven Rasooly (El Sobrante, California); Bradley J. Hernlem (Concord, California); Paula M. Do (Richmond, California)
ABSTRACT	Systems and methods for detecting microbial toxins are disclosed. The system includes an imaging device operable to detect a luminescent signal and an analysis plate having a well to hold a sample containing the microbial toxin. The luminescence is created by a cell line expressing a product capable of reacting directly or indirectly with the microbial toxin to produce the luminescent signal. The signal is processed via an image processing system operable to receive the luminescent signal detected by the imaging device and convert the luminescent signal to a quantitative measurement correlated to an amount of the microbial toxin present in the sample.
FILED	Tuesday, July 11, 2017
APPL NO	15/646177
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/14 (20130101) C12Q 1/6897 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/76 (20130101) G01N 21/763 (20130101) G01N 21/6428 (20130101) G01N 2333/31 (20130101)
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10578358 — Intermittent infrared drying for brewery-spent grain

US 10578358	McHugh et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Regrained (San Francisco, California)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Regrained, Inc. (Burlingame, California)
INVENTOR(S)	Tara H. McHugh (Albany, California); Roberto D. Avena Bustillos (Davis, California); Donald A. Olson (Isleton, California); Zhongli Pan (El Macero, California); Daniel J. Kurzrock (San Francisco, California); Jordan L. Schwartz (San Francisco, California)
ABSTRACT	The system for processing brewery spent grains (BSG) includes a specific intermittent infrared (IR) heating and stirring protocol designed to produce a unique dried BSG product that can be used whole or ground up and used as a quality flour suitable for human consumption.
FILED	Tuesday, March 27, 2018
APPL NO	15/937131
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 3/30 (20130101) Original (OR) Class F26B 17/045 (20130101) F26B 25/002 (20130101) F26B 25/04 (20130101) F26B 2200/06 (20130101)
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10578598 — Nanoreactors as thermal history indicators

US 10578598	Gunasekaran et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Sundaram Gunasekaran (Madison, Wisconsin); Yi-Cheng Wang (Madison, Wisconsin)
ABSTRACT	Nanoreactors comprising a metal precursor in a carrier are provided as well as methods of initiating, methods of preparing, and methods of using nanoreactors. In some embodiments, upon exposure to heat, the metal precursor forms nanoparticles that can be detected, e.g., by detecting a color change in the nanoreactor and/or by detecting the number and/or size and/or size distribution and/or shape of the nanoparticles. The nanoreactors can be used, in some embodiments, as time-temperature indicators for perishable goods.
FILED	Wednesday, June 08, 2016
APPL NO	15/176550
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/02 (20130101) Original (OR) Class
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Small Business Administration (SBA)

10575517 — Pollen field conditioning and preservation method

US 10575517	Cope et al.
FUNDED BY	Small Business Administration (SBA) Small Business Innovation Research (SBIR) Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Accelerated Ag Technologies, LLC (Ankeny, Iowa)
ASSIGNEE(S)	Accelerated Ag Technologies, LLC (Ankeny, Iowa)
INVENTOR(S)	Jason Cope (Ankeny, Iowa); George Singletary (Ankeny, Iowa); Todd Krone (Johnston, Iowa); Sara Katherine Etter (Mitchellville, Iowa)
ABSTRACT	Described are methods of preserving pollen, which may be subsequently stored. A method of the present invention includes collecting fresh pollen and introducing the pollen to a controlled environment which regulates pollen moisture content. The controlled environment may have a temperature ranging from about −10-10° C.; an adjustable and programmable relative humidity; a continuous, adjustable positive or negative air flow; and a flow of one or more continuously refreshed, selected gases which displace oxygen. In another embodiment of the method, the controlled environment may have a relative humidity from about 50-100%; a temperature from about −10-10° C.; and air pressure from about 15-150 kPa. In all embodiments of the method, an optional field conditioning step may be performed. The field conditioning step may include subjecting the pollen to an environment controlled for relative humidity, temperature, and air pressure such that the initial pollen moisture content may be adjusted to a target moisture content.
FILED	Thursday, April 13, 2017
APPL NO	15/486737
ART UNIT	1662 — Plants
CURRENT CPC	Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 7/00 (20130101) New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/02 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 3/00 (20130101) Original (OR) Class
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10575710 — Super absorbing composite material, form factors created therefrom, and methods of production

US 10575710	Kumar et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) United States Marine Corps (USMC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	OCEANIT LABORATORIES, INC. (Honolulu, Hawaii)
ASSIGNEE(S)	OCEANIT LABORATORIES, INC. (Honolulu, Hawaii)
INVENTOR(S)	Ashavani Kumar (Honolulu, Hawaii); Sumil Singh Thapa (Honolulu, Hawaii)
ABSTRACT	Super absorbent material used for drying that integrates super absorbent non-woven fibrous mats with other material, as for example wicking material, are described. The fibrous mats consist of polymeric material embedded with particles of super absorbent polymer. The wicking material may be lightweight knitted fabric that actively absorbs and wicks liquid across the fabric surface. The materials are fabricated as single layer or multiple layers and demonstrate a variety of form factors suitable to the intended use. The super absorbent materials may incorporate additional functionalities, such as antifungal or antibacterial, for biomedical uses.
FILED	Friday, July 24, 2015
APPL NO	14/809090
ART UNIT	3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Domestic Washing or Cleaning; Suction Cleaners in General A47L 23/20 (20130101) Original (OR) Class Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/539 (20130101) A61F 2013/53908 (20130101) A61F 2013/530226 (20130101) A61F 2013/530481 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/022 (20130101) B32B 29/02 (20130101) B32B 2264/02 (20130101) B32B 2307/7145 (20130101)
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10576514 — Devices and techniques relating to landfill gas extraction

US 10576514	Campanella et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Directorate of Technology, Innovation and Partnerships (TIP) Translational Impacts (TI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Loci Controls, Inc. (Fall River, Massachusetts)
ASSIGNEE(S)	Loci Controls, Inc. (Fall River, Massachusetts)
INVENTOR(S)	Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts)
ABSTRACT	A control system for controlling extraction of landfill gas, comprising: at least one sensor configured to measure one or more characteristics of landfill gas; at least one flow control mechanism disposed in well piping and configured to control flow of the landfill gas through the well piping; and at least one processor configured to: obtain a measured concentration of a first gas in landfill gas; determine whether the measured concentration of the first gas is either less than a first threshold concentration or greater than a second threshold concentration; when it is determined that the measured concentration is less than the first threshold concentration, control the at least one flow control mechanism to reduce flow rate of landfill gas; and when it is determined that the concentration is greater than the second threshold concentration, control the at least one flow control mechanism to increase the flow rate of landfill gas.
FILED	Friday, April 21, 2017
APPL NO	15/493174
ART UNIT	3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101)
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10576515 — Devices and techniques relating to landfill gas extraction

US 10576515	Campanella et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Directorate of Technology, Innovation and Partnerships (TIP) Translational Impacts (TI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Loci Controls, Inc. (Fall River, Massachusetts)
ASSIGNEE(S)	Loci Controls, Inc. (Fall River, Massachusetts)
INVENTOR(S)	Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts)
ABSTRACT	A control system for controlling extraction of landfill gas, the system comprising: at least one sensor; at least one flow control mechanism; and at least one processor configured to perform: obtaining a first measure of energy content in a first portion of landfill gas; controlling the at least one flow control mechanism to increase a flow rate of landfill gas; after the controlling, obtaining a second measure of energy content in a second portion of landfill gas; when it is determined that the second measure of energy content is greater than the first measure of energy content, controlling the at least one flow control mechanism to increase the flow rate of landfill gas; and when it is determined that the second measure of energy content is less than the first measure of energy content, controlling the at least one flow control mechanism to decrease the flow rate of landfill gas.
FILED	Friday, April 21, 2017
APPL NO	15/493184
ART UNIT	3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101)
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Department of Veterans Affairs (DVA)

10576091 — Tomatidine, analogs thereof, compositions comprising same, and uses for same

US 10576091	Adams et al.
FUNDED BY	Department of Veterans Affairs (DVA) DVA Office of Research and Development (DVAORD) Biomedical Laboratory Research and Development (BLRD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S)	UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S)	Christopher M. Adams (Iowa City, Iowa); Michael C. Dyle (Iowa City, Iowa); Michael Welsh (Riverside, Iowa)
ABSTRACT	In one aspect, the invention relates to methods for promoting muscle hypertrophy or decreasing adiposity by providing to an animal in need thereof an effective amount of a compound. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED	Friday, June 08, 2018
APPL NO	16/003184
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Fodder A23K 20/121 (20160501) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/10 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Steroids C07J 53/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101)
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10577371 — Small molecule histone methyltransferase SUV39H1 inhibitor and uses thereof

US 10577371	Lu et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Augusta University Research Institute, Inc. (Augusta, Georgia); Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S)	Augusta University Research Institute, Inc. (Augusta, Georgia); Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Chunwan Lu (Augusta, Georgia); Iryna Lebedyeva (Augusta, Georgia); Kebin Liu (Augusta, Georgia)
ABSTRACT	Compositions for the inhibition of SUV39H1 methyltransferase activity and methods of use thereof are provided. The disclosed compositions may be used for treating certain types of cancer, inducing apoptosis in a cancer cell, increasing cell sensitivity to FasL-induced apoptosis, and overcoming cancer cell resistance to apoptosis and/or certain types of cancer immunotherapy.
FILED	Tuesday, September 18, 2018
APPL NO	16/134306
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/407 (20130101) A61K 31/407 (20130101) A61K 39/3955 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class Peptides C07K 16/2818 (20130101) C07K 2317/76 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

National Security Agency (NSA)

10579425 — Power aware scheduling of requests in 3D chip stack

US 10579425	Jacob et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Philip Jacob (Congers, New York); James P. Coghlan (Wappingers Falls, New York); Michael Grassi (Shokan, New York); Kirk Pospesel (Clinton Corners, New York); Marcel Schaal (Stuttgart, Germany); Douglas J. Joseph (Danbury, Connecticut)
ABSTRACT	A computer implemented method and system for managing power in a 3D chip stack formed of multiple memory layers each having a plurality memory banks and a plurality of Through-Silicon-Vias (TSVs) connecting the memory banks. The TSVs are arranged in a plurality of subsets, each subset of TSVs connecting a corresponding vertical stack of memory banks aligned across a plurality of memory layers. The method includes determining a power delivery budget for each subset of TSVs connecting the corresponding vertical stack of memory banks based on memory requests, keeping track of memory requests to the memory banks of each vertical stack of memory banks and scheduling the memory requests to the memory banks of each vertical stack of memory banks based on the power budget. The memory controller is configured with a scorecard scheduler to manage the memory requests based on the power budget.
FILED	Thursday, October 04, 2018
APPL NO	16/151850
ART UNIT	2196 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/48 (20130101) G06F 9/50 (20130101) G06F 9/4806 (20130101) G06F 9/4843 (20130101) G06F 9/4881 (20130101) G06F 9/4893 (20130101) Original (OR) Class G06F 9/5094 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10579457 — Processor for achieving flow integrity and a method of providing notice of a fault in control flow

US 10579457	White
FUNDED BY	National Security Agency (NSA)
APPLICANT(S)	The Government of the United States as Represented by the Director, National Security Agency (Fort George G. Meade, Maryland)
ASSIGNEE(S)	Government of the United States, as represented by Director National Security Agency (, None)
INVENTOR(S)	Andrew H White (Baltimore, Maryland)
ABSTRACT	A processor and methods are provided for detecting fault in a control flow. The processor includes an instruction set architecture defining a pair of FLOWSET and FLOWCHECK opcodes and FLOWSET and FLOWCHECK operations. This pair of opcodes and associated operation works together with a CFI shadow stack to detect faults in an intended flow of instructions. Upon detection of a fault, a fault notice is provided. The methods of detecting fault in a control flow may be implemented using hardware or software and a shadow stack.
FILED	Friday, November 03, 2017
APPL NO	15/802927
ART UNIT	2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electric Digital Data Processing G06F 9/3005 (20130101) G06F 11/0721 (20130101) G06F 11/0772 (20130101) Original (OR) Class G06F 21/54 (20130101) G06F 21/554 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Central Intelligence Agency (CIA)

10581176 — Thin-film sensor antenna

US 10581176	Puchades et al.
FUNDED BY	Central Intelligence Agency (CIA) Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	Ivan Puchades (Honeoye Falls, New York); Brian J. Landi (Rochester, New York); Jamie E. Rossi (Penfield, New York); Cory D. Cress (Alexandria, Virginia)
ASSIGNEE(S)	Rochester Institute of Technology (Rochester, New York)
INVENTOR(S)	Ivan Puchades (Honeoye Falls, New York); Brian J. Landi (Rochester, New York); Jamie E. Rossi (Penfield, New York); Cory D. Cress (Alexandria, Virginia)
ABSTRACT	A sensor antenna including a thin film material constructed in the shape of an antenna having a response, the material including a sheet resistance capable of being modified by an external stimulus where the antenna response varies over a range of sheet resistance values; method of making a sensor antenna; system including a sensor antenna; and method for operating a thin film sensor antenna including providing a thin film sensor antenna; exposing the sensor antenna to an external stimulus, simultaneously sensing the external stimulus while varying the sensor antenna response, measuring the change in the sensor antenna response, and correlating the measured response to a known change in the stimulus are disclosed.
FILED	Wednesday, May 10, 2017
APPL NO	15/591712
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/16 (20130101) Antennas, i.e Radio Aerials H01Q 1/368 (20130101) H01Q 21/0087 (20130101) Original (OR) Class Transmission H04B 17/12 (20150115) H04B 17/21 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Homeland Security (DHS)

10581893 — Modeling of attacks on cyber-physical systems

US 10581893	Warnick et al.
FUNDED BY	Department of Homeland Security (DHS) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	BRIGHAM YOUNG UNIVERSITY (Provo, Utah); Washington State University (Pullman, Washington)
ASSIGNEE(S)	Brigham Young University (BYU) (Provo, Utah); Washington State University (Pullman, Washington)
INVENTOR(S)	Sean Warnick (Provo, Utah); Sandip Roy (Pullman, Washington)
ABSTRACT	Techniques of preventing sabotage attacks in cyber-physical systems involve automatically identifying links between nodes of a graph representing cyber-physical systems as vulnerable to sabotage attacks according to a vulnerability metric for each link. The vulnerability metric used depends on the particular sabotage attack used to determine the vulnerable links. Once a computer configured to design cyber-physical systems based on vulnerability to sabotage attacks receives data representing the graph, the computer enumerates the possible links between nodes of the graph along which a sabotage attack may be performed. For each of those links, the computer computes the vulnerability metric. The computer then ranks the links according to respective values of the vulnerability metric. Based on the ranking, a designer may then perform a mitigation analysis that results in changes to the graph to reduce the vulnerability at each node accessible to a malicious actor.
FILED	Wednesday, December 06, 2017
APPL NO	15/833693
ART UNIT	2493 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 7/08 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101) Original (OR) Class H04L 63/1466 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Non-Profit Organization (NPO)

10577638 — Systems, devices, and methods for microbial detection and identification, and antimicrobial susceptibility testing

US 10577638	Srinivasan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Dental and Craniofacial Research (NIDCR) Non-Profit Organization (NPO) American Heart Association (AHA)
APPLICANT(S)	Anand Srinivasan (San Antonio, Texas); Anand K. Ramasubramanian (San Antonio, Texas); Jose L. Lopez-Ribot (San Antonio, Texas); Christopher R. Frei (San Antonio, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Anand Srinivasan (San Antonio, Texas); Anand K. Ramasubramanian (San Antonio, Texas); Jose L. Lopez-Ribot (San Antonio, Texas); Christopher R. Frei (San Antonio, Texas)
ABSTRACT	The present disclosure provides for systems, devices, products, and methods for detecting and identifying microbial organisms in a sample as well as testing antimicrobial susceptibility of microbial organisms.
FILED	Tuesday, September 23, 2014
APPL NO	15/023568
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

U.S. Agency for International Development (USAID)

10578851 — Automated hardware and software for mobile microscopy

US 10578851	Fletcher et al.
FUNDED BY	U.S. Agency for International Development (USAID)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Daniel A. Fletcher (Berkeley, California); Michael V. D'Ambrosio (Berkeley, California); Arunan Skandarajah (Berkeley, California); Frank B. Myers, III (Oakland, California); Clay D. Reber (Berkeley, California)
ABSTRACT	An automated slide scanning system, comprising one or more optical elements, including an objective, having an optical path configured to be disposed within view of a camera of a portable device. An automated stage disposed within the optical path, the automated stage comprising a platform configured for receiving a slide containing a biological sample and having a drive mechanism for translating the stage in at least one direction with respect to said objective. A communications interface coupled to the automated stage, and is configured for receiving a command from the portable device to control operation of the mechanical stage.
FILED	Thursday, April 13, 2017
APPL NO	15/487266
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 21/0008 (20130101) G02B 21/26 (20130101) Original (OR) Class G02B 21/365 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

10578406 — Suspended floor assembly

US 10578406	Kremar et al.
FUNDED BY
APPLICANT(S)	Pratt and Miller Engineering and Fabrication, Inc. (New Hudson, Michigan)
ASSIGNEE(S)	PRATT and MILLER ENGINEERING AND FABRICATION, INC. (New Hudson, Michigan)
INVENTOR(S)	Jason Kremar (Mooresville, North Carolina); Kevin R. Kwiatkowski (Ann Arbor, Michigan); Aaron Ward (Charlotte, North Carolina); Christopher Watson (Ypsilanti, Michigan)
ABSTRACT	A vehicle has improved energy absorbing capability and occupants have increased blast survivability. The vehicle includes a suspended floor assembly. The floor assembly may be suspended by, at least in part, one or more suspensions arms that have an extendable portion. The floor assembly may also have a yaw plane energy absorber between the floor assembly and a wall of the vehicle.
FILED	Monday, April 09, 2018
APPL NO	15/948344
ART UNIT	3612 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Motor Vehicles; Trailers B62D 25/2009 (20130101) B62D 25/2072 (20130101) B62D 39/00 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 7/042 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10581177 — High frequency polymer on metal radiator

US 10581177	Isom et al.
FUNDED BY
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Robert S. Isom (Allen, Texas); Andrew J. Marquette (Redondo Beach, California); Jason G. Milne (Hawthorne, California)
ABSTRACT	In one aspect, a unit cell of a phased array antenna includes a metal plate having a hole, a first side and a second side opposite the first side, a first plurality of laminate layers disposed on the first side, a second plurality of layers disposed on the second side of the metal plate, a radiator disposed in the first plurality of layer on the first side, a feed circuit disposed in the second plurality of laminate layers on the second side and configured to provide excitation signals to the radiator and a first plurality of vias extending through the hole connecting the feed circuit to the radiator.
FILED	Thursday, December 15, 2016
APPL NO	15/379775
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 3/26 (20130101) H01Q 9/285 (20130101) H01Q 9/0407 (20130101) H01Q 9/0492 (20130101) H01Q 21/0006 (20130101) H01Q 21/22 (20130101) H01Q 21/0025 (20130101) H01Q 21/062 (20130101) Original (OR) Class H01Q 21/0087 (20130101) H01Q 25/001 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10581407 — Scalable fir filter

US 10581407	Skinner et al.
FUNDED BY
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S)	Kristina M. Skinner (Hawthorne, California); Tyler J. Thrane (El Segundo, California); Jason A. Ching (Irvine, California)
ABSTRACT	A Scalable Finite Impulse Response (“SFIR”) filter is disclosed. The SFIR filter includes a pre-processing section, a post-processing section, and a finite impulse response (“FIR”) Matrix. The FIR Matrix includes a plurality of filter taps and a plurality of signal paths in signal communication with each filter tap. The plurality of signal paths are arranged to allow re-configurable data throughput between the each filter tap and the pre-processing section and post-processing section are in signal communication with the FIR Matrix.
FILED	Tuesday, May 08, 2018
APPL NO	15/974687
ART UNIT	2182 — Computer Architecture and I/O
CURRENT CPC	Impedance Networks, e.g Resonant Circuits; Resonators H03H 17/06 (20130101) H03H 17/0211 (20130101) H03H 17/0223 (20130101) Original (OR) Class H03H 2017/0245 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, March 03, 2020.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200303.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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