FedInvent™ Patents
Patent Details for Tuesday, March 17, 2020
This page was updated on Monday, March 27, 2023 at 06:02 AM GMT
Department of Health and Human Services (HHS)
| US 10588511 | Contijoch et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Francisco Contijoch (San Diego, California); Walter R. T. Witschey (Philadelphia, Pennsylvania); Robert C. Gorman (Lower Gwynedd, Pennsylvania); Yuchi Han (Philadelphia, Pennsylvania); Joseph H. Gorman, III (Lower Gwynedd, Pennsylvania) |
| ABSTRACT | A retrospective reconstruction method uses cardiac self-gating for patients with severe arrhythmias. Self-gated myocardial systolic and diastolic motion is determined from low-spatial and high-temporal resolution images and then the MRI-dataset is retrospectively reconstructed to obtain high quality images. The method uses undersampled image reconstruction to obtain the low-spatial and high-temporal resolution images, including those of different beat morphologies. Processing of these images is utilized to generate a cardiac phase signal. This signal allows for arrhythmia detection and cardiac phase sorting. The cardiac phase signal allows for detection of end-systolic and diastolic events which allows for improved sampling efficiency. In the case of frequent and severe arrhythmia, the method utilizes data from the normal and interrupted beats to improve sampling and image quality. |
| FILED | Friday, April 24, 2015 |
| APPL NO | 15/304176 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0044 (20130101) Original (OR) Class A61B 5/055 (20130101) A61B 5/7289 (20130101) A61B 2576/023 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4824 (20130101) G01R 33/5608 (20130101) G01R 33/5611 (20130101) G01R 33/5614 (20130101) G01R 33/5676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588546 | Schindler et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| INVENTOR(S) | David D. Schindler (Russell, Ohio); Jay L. Alberts (Chagrin Falls, Ohio); Joshua R. Hirsch (Brecksville, Ohio) |
| ABSTRACT | This disclosure relates to a system and method to analyze balance and stability of a patient. Test data for the patient, representing motion of a device affixed to the patient during a test interval (e.g., at a position approximating the center of mass, such as in proximity to the torso), can be received. The test data can be processed to provide processed data (or sensor-derived data) that includes at least one of acceleration data, rotational rate data and rotational position data for the test interval. A biomechanical model can be applied to the processed data to provide center of mass (COM) motion data representing movement of the COM in multiple dimensions for the patient during the test interval. An indication of balance for the patient can be determined based on the COM motion data. The indication of balance can be used to analyze the balance and stability of the patient. |
| FILED | Thursday, June 26, 2014 |
| APPL NO | 14/316217 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1117 (20130101) A61B 5/1121 (20130101) Original (OR) Class A61B 5/4082 (20130101) A61B 5/6898 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/30 (20180101) G16H 50/50 (20180101) G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588572 | Jia et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Yali Jia (Portland, Oregon); David Huang (Portland, Oregon); Yan Li (Portland, Oregon); Acner Camino (Portland, Oregon) |
| ABSTRACT | Described herein is an algorithm to remove decorrelation noise due to bulk motion in optical coherence tomography angiography (OCTA). OCTA B-frames are divided into segments within which the bulk motion velocity could be assumed constant. This velocity is recovered using linear regression of decorrelation versus the logarithm of reflectance in axial lines (A-lines) identified as bulk tissue by percentile analysis. The fitting parameters are used to calculate a reflectance-adjusted threshold for bulk motion decorrelation. Below this threshold, voxels are identified as non-flow tissue, and their flow values are set to zeros. Above this threshold, the voxels are identified as flow voxels and bulk motion velocity is subtracted from each using a nonlinear decorrelation-velocity relationship. Compared to the median-subtraction method, the bulk motion subtraction algorithm described herein improves angiogram signal-to-noise ratio, contrast, vessel density repeatability, and bulk motion noise cleanup, while preserving the connectivity of the vascular networks in the angiogram. |
| FILED | Tuesday, November 07, 2017 |
| APPL NO | 15/805392 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) A61B 5/0066 (20130101) A61B 5/0261 (20130101) A61B 5/7207 (20130101) Original (OR) Class A61B 5/7235 (20130101) A61B 5/7275 (20130101) A61B 2576/02 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 7/11 (20170101) G06T 7/136 (20170101) G06T 7/194 (20170101) G06T 2207/10101 (20130101) G06T 2207/30041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588587 | Samsonov et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Alexey A. Samsonov (Madison, Wisconsin); Julia V. Velikina (Madison, Wisconsin) |
| ABSTRACT | A system and method for reconstructing a series of images of a subject includes acquiring medical image data from the subject with a medical imaging system and reconstructing a series of images of the subject from the acquired medical image data set. The reconstructing includes enforcing general adherence to a non-patient-specific signal model that describes a dependency of image intensity values on at least one variable that is associated with a physical or physiological property by constraining reconstruction of individual images in the series of images using the non-patient-specific model. The reconstructing also includes preserving information in the series of images that deviate from the non-patient-specific model by controlling a requirement of consistency with the non-patient-specific model. |
| FILED | Wednesday, August 23, 2017 |
| APPL NO | 15/683916 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 6/032 (20130101) A61B 6/504 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5601 (20130101) G01R 33/5611 (20130101) G01R 33/5635 (20130101) G01R 33/56308 (20130101) G01R 33/56366 (20130101) G01R 33/56509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588695 | Walsh et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Brigham and Women's Hospital (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Brigham and Women's Hospital (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Conor J. Walsh (Cambridge, Massachusetts); Ellen T. Roche (Cambridge, Massachusetts); Panagiotis Polygerinos (Somerville, Massachusetts); Lucia R. Schuster (Munich, Germany); Jeffrey Michael Karp (Brookline, Massachusetts); Yuhan Lee (Cambridge, Massachusetts); Pedro J. del Nido (Lexington, Massachusetts); Assunta Fabozzo (Jamaica Plain, Massachusetts); Ingeborg Friehs (Newton, Massachusetts); Steven Charles Wasserman (Concord, Massachusetts) |
| ABSTRACT | An insertable light-dispensing catheter device, comprising a shaft including a proximal and distal end, a light guide extending through the shaft, and a mirror displaceably extendable from the catheter into a position where the mirror receives and reflects light emitted from the light guide. The mirror can be in the form of a coating on an inflatable balloon; and the balloon, when inflated, can press a patch against a defect (e.g., a ventricular septical defect), while the light cures an adhesive that binds the patch to the structure with the defect, thereby remedying the defect. |
| FILED | Wednesday, May 13, 2015 |
| APPL NO | 15/310877 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/24 (20130101) Original (OR) Class A61B 2018/0022 (20130101) A61B 2018/00285 (20130101) A61B 2018/00351 (20130101) A61B 2018/00494 (20130101) A61B 2018/00982 (20130101) A61B 2018/2272 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588734 | MacEwan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Matthew R. MacEwan (St. Louis, Missouri); Jingwei Xie (St. Louis, Missouri); Zack Ray (St. Louis, Missouri); Younan Xia (St. Louis, Missouri) |
| ABSTRACT | A three-dimensional electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a flexible deposited fiber network of varying density including a first and second set of set of electrospun fibers. The second set of electrospun fibers is coupled to the first. A first portion of the flexible deposited fiber network includes a higher density of fibers than a second portion of the flexible deposited fiber network, and the tensile strength of first portion is higher than that of the second portion. The scaffold is sufficiently flexible to facilitate application of scaffold to uneven surfaces of the tissue substrate, and enables movement of the scaffold by the tissue substrate. The first and second set of fibers are configured to degrade within three months after application, and each fiber of the deposited fiber network has a diameter of 1-1000 nanometers. |
| FILED | Wednesday, August 14, 2019 |
| APPL NO | 16/540335 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/02 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/22 (20130101) A61L 15/42 (20130101) A61L 27/14 (20130101) A61L 27/50 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/05 (20190201) B29C 48/142 (20190201) Apparatus for Enzymology or Microbiology; C12M 25/14 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0076 (20130101) D01D 5/0092 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/728 (20130101) D04H 3/016 (20130101) D04H 3/073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588761 | Holt et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Brian Mueller Holt (Topanga, California); Sujee Jeyapalina (Salt Lake City, Utah); Roy Drake Bloebaum (Salt Lake City, Utah); Kent Nelson Bachus (Salt Lake City, Utah) |
| ABSTRACT | An abutment system for operatively coupling an implant stem to an exo-prosthesis. The abutment system includes a plurality of interlocking sleeve elements that are operatively coupled to an implant stem positioned within a prepared site of a selected bone. The interlocking sleeve elements of the abutment system are selectively removable and replaceable. |
| FILED | Friday, December 08, 2017 |
| APPL NO | 15/835954 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/78 (20130101) Original (OR) Class A61F 2/2814 (20130101) A61F 2002/502 (20130101) A61F 2002/3055 (20130101) A61F 2002/5083 (20130101) A61F 2002/7887 (20130101) A61F 2220/0041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588853 | Villanueva et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University Of Pittsburgh Of The Commonwealth System Of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Flordeliza Villanueva (Pittsburgh, Pennsylvania); Andrew Carson (New Castle, Pennsylvania); Charles F McTiernan (Pittsburgh, Pennsylvania); Jianjun Wang (Pittsburgh, Pennsylvania) |
| ABSTRACT | The invention pertains to a lipid-based microbubble stably binding a plurality of nucleic acids, and a method of delivering the microbubble and nucleic acids to a specific target site using ultrasound. The delivered nucleic acids create transgenic cells (i.e., for example, a transgenic tumor cell), wherein the transgenic cell expresses the proteins encoded by the delivered nucleic acids. This technology provides a significant improvement for microbubble-drug delivery platforms as known microbubble do not efficiently bind nucleic acids. The improvements described herein include but are not limited to identifying proper lipid proportionality ratios and/or cationic surfactant layers that provide an optimum mechanical index compatible with ultrasonics. Microbubble perfusion and/or nucleic acid delivery may be performed by a combination of imaging and ultrasound/microbubble targeted delivery to simultaneously perform low power two-dimensional imaging and high power microbubble destruction. Such systems are useful in therapeutics and/or diagnositics. For example, the data disclosed herein shows proof of principle in conjunction with the delivery of therapeutic siRNA molecules to slow tumor growth. |
| FILED | Monday, November 13, 2017 |
| APPL NO | 15/811066 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0002 (20130101) Original (OR) Class A61K 9/0009 (20130101) A61K 9/127 (20130101) A61K 9/1272 (20130101) A61K 41/0028 (20130101) A61K 48/0075 (20130101) A61K 48/0083 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) A61N 2007/0039 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 25/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/88 (20130101) C12N 15/111 (20130101) C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588854 | Gower et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Robert Gower (Columbia, South Carolina); Michael Hendley (Columbia, South Carolina) |
| ABSTRACT | Implantable devices including a biocompatible matrix configured for long term location in adipose tissue and a biologically active agent that can be carried by the matrix and delivered to the adipose tissue following implant therein. The biologically active agent can include a modulator or a precursor thereof that can directly or indirectly modify the gene expression of adipose cells, e.g., adipocytes, and thereby modify the presence or quantity of one or more expression products of the adipose tissue that may act locally on distant from the implant site in an endocrine fashion. Modulators can include small molecules (e.g., resveratrol), polynucleotides (e.g., RNAi), or polypeptides (e.g., antibodies or functional fragments thereof). |
| FILED | Wednesday, September 05, 2018 |
| APPL NO | 16/122034 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) Original (OR) Class A61K 9/5031 (20130101) A61K 31/05 (20130101) A61K 31/352 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588884 | Abaffy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Tatjana Abaffy (Durham, North Carolina); Hiro Matsunami (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides, in part, modulators of prostate-specific G-protein receptor (OR51E2/PSGR) and methods of treating, preventing, and diagnosing prostate cancer using the same. |
| FILED | Wednesday, November 01, 2017 |
| APPL NO | 15/801258 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/203 (20130101) Original (OR) Class A61K 31/352 (20130101) A61K 31/565 (20130101) A61K 31/568 (20130101) A61K 31/7016 (20130101) A61K 47/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588891 | Brnardic et al. |
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| FUNDED BY |
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| APPLICANT(S) | GlaxoSmithKline Intellectual Property (No. 2) Limited (Brentford, Middlesex, United Kingdom) |
| ASSIGNEE(S) | GlaxoSmithKline Intellectual Property Development Limited (Brentford, Middlesex, United Kingdom) |
| INVENTOR(S) | Edward J. Brnardic (Collegeville, Pennsylvania); Carl A. Brooks (Collegeville, Pennsylvania); Brian Griffin Lawhorn (Collegeville, Pennsylvania); Guosen Ye (Collegeville, Pennsylvania); Linda S. Barton (Collegeville, Pennsylvania); Brian W. Budzik (Collegeville, Pennsylvania); Jay M. Matthews (Collegeville, Pennsylvania); John Jeffrey McAtee (Collegeville, Pennsylvania); Jaclyn R. Patterson (Collegeville, Pennsylvania); Joseph E. Pero (Collegeville, Pennsylvania); Robert Sanchez (Collegeville, Pennsylvania); Matthew Robert Sender (Collegeville, Pennsylvania); Lamont Roscoe Terrell (Collegeville, Pennsylvania); David J. Behm (Collegeville, Pennsylvania); James V. Thomas (Collegeville, Pennsylvania) |
| ABSTRACT | The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists. |
| FILED | Wednesday, September 20, 2017 |
| APPL NO | 16/334391 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 9/0073 (20130101) A61K 9/2059 (20130101) A61K 9/4866 (20130101) A61K 31/40 (20130101) Original (OR) Class A61K 31/407 (20130101) A61K 31/424 (20130101) A61K 31/427 (20130101) A61K 31/429 (20130101) A61K 31/501 (20130101) A61K 31/506 (20130101) A61K 31/695 (20130101) A61K 31/4025 (20130101) A61K 31/4155 (20130101) A61K 31/4245 (20130101) A61K 31/4439 (20130101) A61K 31/5386 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 207/48 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 409/12 (20130101) C07D 413/12 (20130101) C07D 417/12 (20130101) C07D 491/107 (20130101) C07D 498/10 (20130101) C07D 513/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0812 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588902 | Smith et al. |
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| FUNDED BY |
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| APPLICANT(S) | OyaGen, Inc. (Rochester, New York); Harold C. Smith (Rochester, New York); Ryan P. Bennett (Clifton Springs, New York) |
| ASSIGNEE(S) | OyaGen, Inc. (Rochester, New York) |
| INVENTOR(S) | Harold C. Smith (Rochester, New York); Ryan P. Bennett (Clifton Springs, New York) |
| ABSTRACT | The present invention relates to the use of camptothecin derivatives as anti-HIV agents that disrupt self-association of the viral infectivity factor (Vif) found in HIV and other retroviruses. The present invention also relates to methods of identifying agents that disrupt VIf self-association and methods of using these agents, including methods of treating or preventing HIV infection. |
| FILED | Tuesday, June 24, 2014 |
| APPL NO | 14/900666 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) Original (OR) Class A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) G01N 2333/15 (20130101) G01N 2333/163 (20130101) G01N 2500/02 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588935 | Blumberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); BIOGEN MA INC. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); BIOGEN MA INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Richard S. Blumberg (Waltham, Massachusetts); Timo Rath (Cambridge, Massachusetts); Kristi Baker (Brookline, Massachusetts); Adam Mezo (Carmel, Indiana); Zachary Taylor (Crestview Hills, Kentucky); Kevin McDonnell (Lexington, Massachusetts); Rosa Maria Silva Garcia Grenha (Arlington, Massachusetts) |
| ABSTRACT | The invention provided herein includes isolated polypeptides that specifically block the interaction between neonatal Fc receptor (FcRn) and albumin. Blocking the interaction treats diseases and conditions caused by increased amounts of albumin or modified albumin that possesses pathogenic properties wherein it is deemed desirable to decrease albumin levels. Accordingly, also provided are methods of using these isolated polypeptides to treat various diseases and conditions caused by increased amounts of albumin or modified albumin that possesses pathogenic properties. The invention provided herein also includes isolated polypeptides capable of binding to a non-IgG and non-albumin competitive site on an FcRn alpha 3 domain. These can be useful for tracking FcRn without inhibiting IgG or albumin binding or function. Accordingly, the invention also includes methods and systems to track FcRn without inhibiting IgG or albumin binding or function. |
| FILED | Wednesday, March 06, 2019 |
| APPL NO | 16/293879 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/10 (20130101) Original (OR) Class A61K 47/54 (20170801) Peptides C07K 7/08 (20130101) C07K 14/001 (20130101) C07K 14/765 (20130101) C07K 14/70535 (20130101) C07K 2319/00 (20130101) C07K 2319/31 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588937 | Barasch et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Jonathan Barasch (New York, New York); Andong Qiu (Bronx, New York) |
| ABSTRACT | In one aspect the present invention is directed to mutant Neutrophil Gelatinase Associated Lipocalin (NGAL) proteins that have the ability to bind to siderophores, such as enterochelin, and to chelate and transport iron, and that are excreted in the urine. Such NGAL mutants, and complexes thereof with siderophores, can be used to clear excess iron from the body, for example in the treatment of iron overload. The NGAL mutants of the invention also have antibacterial activity and can be used in the treatment of bacterial infections, such as those of the urinary tract. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/376327 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/357 (20130101) A61K 38/1709 (20130101) Original (OR) Class Peptides C07K 14/47 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588941 | Xiong et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Na Xiong (State College, Pennsylvania); Mingcan Xia (Brookline, Massachusetts) |
| ABSTRACT | The invention provides compositions and methods for targeting CCR10 and/or the CCR10/ligand axis to modulate the immune response in a subject. |
| FILED | Friday, July 20, 2018 |
| APPL NO | 16/040592 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/195 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 14/523 (20130101) C07K 14/7158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588954 | Boyd et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARTIFICIAL CELL TECHNOLOGIES, INC. (New Haven, Connecticut) |
| ASSIGNEE(S) | ARTIFICIAL CELL TECHNOLOGIES, INC. (New Haven, Connecticut) |
| INVENTOR(S) | James Gorham Boyd (Madison, Connecticut); Thomas J. Powell (Madison, Connecticut) |
| ABSTRACT | Described herein are multilayer films that include modified polypeptide epitopes from Plasmodium falciparum, specifically a modified T* epitope. The multilayer films are capable of eliciting an immune response in a host upon administration to the host. The multilayer films can include at least one designed peptide that includes the modified T* polypeptide epitope from a Plasmodium protozoan. |
| FILED | Thursday, April 05, 2018 |
| APPL NO | 15/946257 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/146 (20130101) A61K 9/167 (20130101) A61K 9/1641 (20130101) A61K 39/015 (20130101) Original (OR) Class A61K 39/39 (20130101) Peptides C07K 7/08 (20130101) Technologies for Adaptation to Climate Change Y02A 50/412 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588964 | Blander et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Julie Magarian Blander (North Haven, Connecticut); Leif Erik Sander (Berlin, Germany) |
| ABSTRACT | The invention features vaccine adjuvants comprising prokaryotic mRNA, and methods of vaccination using the adjuvants. |
| FILED | Friday, November 10, 2017 |
| APPL NO | 15/809130 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/522 (20130101) A61K 2039/585 (20130101) Technologies for Adaptation to Climate Change Y02A 50/403 (20180101) Y02A 50/478 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588984 | de los Pinos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aura Biosciences, Inc. (Cambridge, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Aura Biosciences, Inc. (Cambridge, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Elisabet de los Pinos (Brookline, Massachusetts); John Todd Schiller (Kensington, Maryland); Rhonda C. Kines (Washington, District of Columbia); John MacDougall (Hingham, Massachusetts) |
| ABSTRACT | The present disclosure is directed to methods and compositions for the diagnosis and/or treatment of tumors, such as ocular tumors, using virus-like particles conjugated to photosensitive molecules. |
| FILED | Wednesday, September 26, 2018 |
| APPL NO | 16/143147 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 41/0057 (20130101) A61K 41/0071 (20130101) A61K 47/64 (20170801) A61K 47/6901 (20170801) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/585 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Peptides C07K 1/13 (20130101) C07K 14/025 (20130101) C07K 16/32 (20130101) C07K 16/084 (20130101) C07K 2317/33 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/20023 (20130101) C12N 2710/20033 (20130101) C12N 2710/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588997 | Pokorski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Jonathan Pokorski (Cleveland, Ohio) |
| ABSTRACT | A polymer nanofiber scaffold includes a plurality of melt extruded nanofibers that are chemically modified to append surface functionality to the nanofibers. |
| FILED | Tuesday, April 24, 2018 |
| APPL NO | 15/961712 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/02 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/26 (20130101) Original (OR) Class A61L 15/26 (20130101) A61L 15/26 (20130101) A61L 15/44 (20130101) A61L 15/425 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/56 (20130101) A61L 27/60 (20130101) A61L 2400/12 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 67/04 (20130101) C08L 71/02 (20130101) C08L 71/02 (20130101) C08L 71/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589002 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Hongbin Jiang (Export, Pennsylvania); William R. Wagner (Gibsonia, Pennsylvania); Tomo Yoshizumi (Pittsburgh, Pennsylvania); Yang Zhu (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided are novel biocompatible copolymers, compositions comprising the copolymers, and methods of using the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodeable in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers. |
| FILED | Tuesday, April 14, 2015 |
| APPL NO | 15/304016 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0024 (20130101) A61K 47/30 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) Original (OR) Class A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2430/20 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589087 | Tyler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wicab, Inc. (Middleton, Wisconsin) |
| ASSIGNEE(S) | WICAB, INC. (Middleton, Wisconsin) |
| INVENTOR(S) | Mitchell Eugene Tyler (Madison, Wisconsin); Yuri Petrovich Danilov (Middleton, Wisconsin); Paul Bach-y-Rita (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to systems and methods for management of brain and body functions and sensory perception. For example, the present invention provides systems and methods of sensory substitution and sensory enhancement (augmentation) as well as motor control enhancement. The present invention also provides systems and methods of treating diseases and conditions, as well as providing enhanced physical and mental health and performance through sensory substitution, sensory enhancement, and related effects. |
| FILED | Tuesday, April 21, 2015 |
| APPL NO | 14/692419 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/112 (20130101) A61B 5/486 (20130101) A61B 5/0492 (20130101) A61B 5/682 (20130101) A61B 5/686 (20130101) A61B 5/726 (20130101) A61B 5/1116 (20130101) A61B 5/1123 (20130101) A61B 5/1124 (20130101) A61B 5/4005 (20130101) A61B 5/4023 (20130101) A61B 5/4047 (20130101) A61B 5/4528 (20130101) A61B 5/6803 (20130101) A61B 5/7225 (20130101) A61B 5/7455 (20130101) A61B 5/7475 (20130101) A61B 5/14553 (20130101) A61B 2562/046 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0548 (20130101) Original (OR) Class A61N 1/36025 (20130101) A61N 1/36082 (20130101) A61N 1/36103 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/012 (20130101) G06F 3/015 (20130101) G06F 3/016 (20130101) G06F 3/038 (20130101) G06F 3/0383 (20130101) G06F 3/03547 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589096 | Tandon |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Nitin Tandon (Houston, Texas) |
| ABSTRACT | This invention relates generally to systems and methods for multifocal direct brain stimulation to enhance cognitive processing, such as but not limited to stimulation-induced modulation of memory. |
| FILED | Tuesday, April 25, 2017 |
| APPL NO | 15/496444 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 6/037 (20130101) A61B 6/501 (20130101) A61B 8/0808 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) A61N 1/0534 (20130101) A61N 1/36082 (20130101) Original (OR) Class A61N 1/36132 (20130101) A61N 1/36153 (20130101) A61N 1/36157 (20130101) A61N 1/36171 (20130101) A61N 1/36175 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589098 | Jung |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ranu Jung (Coral Gables, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Ranu Jung (Coral Gables, Florida) |
| ABSTRACT | Adaptive systems and methods for automatically determining and continuously updating stimulation parameters for adjusting ventilation to accommodate a patient's specific physiology, metabolic needs, and muscle state are disclosed herein. Having a closed loop implementation, the system may comprise a controller including a neuromorphic controlled adaptive feed-forward Pattern Generator/Pattern Shaper (PG/PS) assembly, which controls respiratory muscle movement using electrical stimulation. This PG/PS assembly comprises a biomimetic design where the pattern generator includes a neural network mimicking the simplified connectivity pattern of respiratory related neurons in the brain stem to produce a rhythmic breathing pattern frequency and the pattern shaper includes a neural network mimicking the simplified connectivity pattern of neurons to produce a stimulus control signal. This biomimetic design for the controller automatically customizes and continually updates stimulation parameters to achieve a desired breathing pattern and, thereby, slow the development of muscle fatigue. |
| FILED | Friday, December 15, 2017 |
| APPL NO | 15/842956 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3601 (20130101) A61N 1/3611 (20130101) A61N 1/36139 (20130101) Original (OR) Class A61N 1/37217 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589102 | Mech et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Brian V Mech (Santa Carita, California); Robert J Greenberg (Los Angeles, California); Honggang Jiang (Valencia, California) |
| ABSTRACT | An implantable micro-miniature device is disclosed. The device comprises a thin hermetic insulating coating and at least one thin metal secondary coating over the hermetic insulating layer in order to protect the insulating layer from the erosive action of body fluids or the like. In one embodiment the insulating layer is ion beam assisted deposited (IBAD) alumina and the secondary coating is titanium. The device may be a small electronic device such as a silicon integrated circuit chip. The thickness of the insulating layer may be ten microns or less and the thickness of the secondary layer may be between about 0.1 and about 15 microns. |
| FILED | Tuesday, October 04, 2016 |
| APPL NO | 15/284877 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/372 (20130101) A61N 1/375 (20130101) A61N 1/37205 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/28 (20130101) C23C 14/081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589108 | Radziemski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Piezo Energy Technologies LLC (Tucson, Arizona) |
| ASSIGNEE(S) | Piezo Energy Technologies LLC (Tucson, Arizona) |
| INVENTOR(S) | Leon J. Radziemski (Tucson, Arizona); Inder Raj Singh Makin (Mesa, Arizona); Harry Jabs (Oakland, California); Juan Carlos Lopez Tonazzi (Tucson, Arizona) |
| ABSTRACT | A system for providing energy to a bio-implantable medical device includes an acoustic energy delivery device and a bio-implantable electroacoustical energy converter. The acoustic energy delivery device generates acoustic energy with a multi-dimensional array of transmitting electroacoustical transducers. The acoustic energy is received by one or more receiving electroacoustical transducers in the bio-implantable electroacoustical energy converter. The receiving electroacoustical transducers convert the acoustic energy to electrical energy to power the bio-implantable medical device directly or indirectly. An external alignment system provides lateral and/or angular positioning of an ultrasound energy transmitter over an ultrasound energy receiver. The acoustic energy transmitter alignment system comprises either or both x-y-z plus angular positioning components, and/or a substantially multi-dimensional array of transmitters plus position sensors in both the transmitter and receiver units. |
| FILED | Wednesday, February 27, 2019 |
| APPL NO | 16/287572 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4041 (20130101) A61B 2560/0219 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/025 (20130101) A61N 1/3787 (20130101) Original (OR) Class A61N 1/37223 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/15 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589123 | Deisseroth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Karl Deisseroth (Stanford, California); Feng Zhang (Cambridge, Massachusetts); Viviana Gradinaru (La Cañada Flintridge, California) |
| ABSTRACT | Stimulation of target cells using light, e.g., in vitro, is implemented using a variety of methods and devices. One example involves a vector for delivering a light-activated NpHR-based molecule comprising a nucleic acid sequence that codes for light-activated NpHR-based molecule and a promoter. Either a high expression of the molecule manifests a toxicity level that is less than about 75%, or the light-activated NpHR-based proteins are expressed using at least two NpHR-based molecular variants. Each of the variants characterized in being useful for expressing a light-activated NpHR-based molecule that responds to light by producing an inhibitory current to dissuade depolarization of the neuron. Other aspects and embodiments are directed to systems, methods, kits, compositions of matter and molecules for ion pumps or for controlling inhibitory currents in a cell (e.g., in in vivo and in vitro environments). |
| FILED | Monday, July 24, 2017 |
| APPL NO | 15/658090 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0333 (20130101) A01K 2217/052 (20130101) A01K 2227/703 (20130101) A01K 2267/0356 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/005 (20130101) A61K 48/0058 (20130101) A61K 48/0083 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Original (OR) Class A61N 5/0613 (20130101) A61N 5/0622 (20130101) Peptides C07K 14/00 (20130101) C07K 14/195 (20130101) C07K 14/215 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) C12N 15/86 (20130101) C12N 2710/10343 (20130101) C12N 2710/16643 (20130101) C12N 2740/16043 (20130101) C12N 2740/16071 (20130101) C12N 2750/14143 (20130101) C12N 2830/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589250 | Schopf et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); SOFIE BIOSCIENCES, INC. (Culver City, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); SOFIE BIOSCIENCES, INC. (Culver City, California) |
| INVENTOR(S) | Eric Schopf (Los Angeles, California); Melissa Moore (Beverly Hills, California); R. Michael van Dam (Los Angeles, California); Brandon Maraglia (Los Angeles, California); Alexander Hsiao (Los Angeles, California) |
| ABSTRACT | A device for purifying and formulating a radiopharmaceutical compound includes an automated purification subsystem that automates the loading of a sample into a sample loop for downstream purification via HPLC. A column selector valve is provided to select from one of a plurality of columns. Fractions can be collected as well as the desired product. The device includes an automated formulation subsystem that first sends the product to a dilution reservoir prior to being pneumatically pushed onto a solid phase extraction (SPE) cartridge. Automated rinse, elution, and reconstitution are also performed with the automated formulation subsystem. The device may be directly coupled to the output of an automated radiosynthesizer. |
| FILED | Thursday, September 07, 2017 |
| APPL NO | 15/698350 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2121/00 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/004 (20130101) Original (OR) Class B01J 19/24 (20130101) B01J 2219/00164 (20130101) B01J 2219/00191 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 7/04 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/0005 (20130101) G21G 4/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589272 | El-Zahab et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bilal El-Zahab (Miami Beach, Florida); Ata Dolatmoradi (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Bilal El-Zahab (Miami Beach, Florida); Ata Dolatmoradi (Miami, Florida) |
| ABSTRACT | Devices, systems, and methods for separating cells or vesicles using a thermo-acoustophoretic approach are provided. A microfluidic device can be used for stiffness-based separation of cells or vesicles that otherwise have the same or approximately the same size, shape, and charge, where at least some of the membranes or vesicles have different compositions. The separation can be done by tuning the temperature of the cells or vesicles. |
| FILED | Monday, March 20, 2017 |
| APPL NO | 15/463164 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Separation B01D 21/283 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2300/0887 (20130101) B01L 2300/1822 (20130101) B01L 2400/0436 (20130101) B01L 2400/0451 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/02 (20130101) C12N 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590059 | Chandraratna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Io Therapeutics, Inc. (Santa Ana, California) |
| ASSIGNEE(S) | Io Therapeutics, Inc. (Houston, Texas) |
| INVENTOR(S) | Roshantha A. Chandraratna (San Juan Capistrano, California); Vidyasagar Pradeep Vuligonda (Irvine, California); Thomas Jacks (South Plainfield, New Jersey); Peter Wade (South Plainfield, New Jersey); Andrew Thompson (South Plainfield, New Jersey) |
| ABSTRACT | Provided herein are compounds useful for the preparation of compounds that have retinoid-like biological activity. Also provided herein are processes for the preparation of compounds that have retinoid-like biological activity. |
| FILED | Friday, November 16, 2018 |
| APPL NO | 16/194141 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) A61K 31/198 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 29/44 (20130101) C07C 33/36 (20130101) C07C 33/38 (20130101) C07C 51/255 (20130101) C07C 57/50 (20130101) Original (OR) Class C07C 2601/02 (20170501) C07C 2602/10 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590065 | Blagg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| ASSIGNEE(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| INVENTOR(S) | Brian S. J. Blagg (Lawrence, Kansas); Rick T. Dobrowsky (Olathe, Kansas); Mercy Anyika (Lawrence, Kansas) |
| ABSTRACT | Provided herein are compounds of the formulas: (I) wherein: n, X2, R3, R3′, R4, R4′, R5, R5′, R6, and R6′ are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds may be used for the treatment of diseases, including diabetic peripheral neuropathy or cancer. |
| FILED | Wednesday, June 24, 2015 |
| APPL NO | 15/321289 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/18 (20130101) Original (OR) Class C07C 2601/08 (20170501) C07C 2601/14 (20170501) C07C 2601/16 (20170501) Heterocyclic Compounds C07D 307/20 (20130101) C07D 309/10 (20130101) C07D 311/08 (20130101) C07D 311/16 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590074 | Newman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services, Office of Technology Transfer, National Institutes of Health (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Amy Hauck Newman (Phoenix, Maryland); Oluyomi M. Okunola-Bakare (Beltsville, Maryland); Jianjing Cao (Ellicott City, Maryland) |
| ABSTRACT | Disclosed herein are bisarylmethylthioacetamides and bisarylmethylthioethylamines useful as inhibitors of monoamine transporters. The compounds are potent and/or selective inhibitors of dopamine (DA), serotonin (5-HT), and/or norepinephrine (NE) reuptake via their respective transporters, DAT, SERT and NET. Also disclosed are methods for eliciting a wake-promoting or cognitive or attention enhancing effect and for treating substance use disorders, attention deficit (hyperactivity) disorder, depressive disorders, bipolar disorder or other neuropsychiatric disorders sleep disorders or cognitive impairment using the compounds. |
| FILED | Monday, December 04, 2017 |
| APPL NO | 15/830244 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/135 (20130101) A61K 31/135 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 317/28 (20130101) C07C 317/44 (20130101) C07C 323/25 (20130101) C07C 323/60 (20130101) Original (OR) Class C07C 2601/02 (20170501) Heterocyclic Compounds C07D 295/08 (20130101) C07D 295/088 (20130101) C07D 295/108 (20130101) C07D 295/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590126 | Bray |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THOMAS JEFFERSON UNIVERSITY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THOMAS JEFFERSON UNIVERSITY (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Paul F. Bray (Penn Valley, Pennsylvania) |
| ABSTRACT | A substance of Formula (I) for use as a medicament for the treatment of cardiovascular diseases, wherein R is nitrogen or carbon; R1 is selected from the group consisting of a hydrogen, a trifluoromethyl, a methyloxyphenyl, a phenyl, a C1-C3 phenylalkyl, a halogenated phenyl, a halogenated C1-C3 phenylalkyl, a trifluoromethyloxy, a trifluoromethyl oxyphenyl, and a C1-C3 pyridinylalkyl; R2 is selected from the group consisting of a C1-C3 alkyl alcohol optionally substituted with a C1-C3 alkoxyphenyl, a C1-C3 N-alkylmethanamine, a C1-C3 alkoxymethyl, a C1-C3 phenylalkoxymethyl, a C1-C3 cyclopropylalkoxymethyl, and a methoxyethoxymethyl; and R3 is a phenyl or a methoxypyridinyl; and R4 is selected from the group consisting of a hydrogen, a cyano, a C1-C3 sulfonyl, a nitro, and a trifluoromethyl. |
| FILED | Friday, October 14, 2016 |
| APPL NO | 15/768329 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Heterocyclic Compounds C07D 209/12 (20130101) C07D 209/14 (20130101) C07D 401/04 (20130101) C07D 401/14 (20130101) C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590137 | Matzger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Adam J. Matzger (Ann Arbor, Michigan); Kortney Kersten (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein is a new mercaptopurine form, as a hemihydrate, and methods of making and using the same. |
| FILED | Thursday, February 02, 2017 |
| APPL NO | 16/074438 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) A61P 37/00 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Heterocyclic Compounds C07D 473/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590142 | Saltiel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Alan R. Saltiel (Ann Arbor, Michigan); Hollis D. Showalter (Ann Arbor, Michigan); Scott Larsen (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein is technology relating to deuterated amlexanox and particularly, but not exclusively, to compositions comprising deuterated amlexanox, methods of producing deuterated amlexanox, and uses of deuterated amlexanox. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/953907 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 491/052 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590155 | Kong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Xiangxing Kong (Tempe, Arizona); Yanqing Tian (Tempe, Arizona); Fengyu Su (Tempe, Arizona); Liqiang Zhang (Chandler, Arizona); Deirdre Meldrum (Phoenix, Arizona) |
| ABSTRACT | Mitochondria-targeting potassium sensors and method(s) for making such sensors. The sensor shows a response to potassium and displays a 130-fold dynamic range of fluorescence intensity and high brightness. The sensors response to potassium concentrations was demonstrated to be unaffected by cellular pH value and/or concentrations of other ions. The sensors can be used for monitoring the mitochondrial potassium efflux/influx. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 16/314753 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6596 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/5079 (20130101) G01N 33/6872 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590157 | Blagg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| ASSIGNEE(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| INVENTOR(S) | Brian S. J. Blagg (Lawrence, Kansas); Bhaskar Reddy Kusuma (Lake Ronkonkoma, New York); Teather Sundstrom (Eckelson, North Dakota) |
| ABSTRACT | Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy. |
| FILED | Tuesday, June 26, 2018 |
| APPL NO | 16/018401 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 211/17 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/203 (20130101) C07H 15/207 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590160 | Sauve et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Anthony Sauve (New Rochelle, New York); Farheen Sultana Mohammad (Jackson Heights, New York) |
| ABSTRACT | The invention provides a process for the preparation of nicotinamide mononucleotide having formula (I): The method involves the protection of nicotinamide riboside by ketalization, followed by phosphorylation and then deprotection to provide nicotinamide mononucleotide. |
| FILED | Thursday, March 24, 2016 |
| APPL NO | 15/562336 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/02 (20130101) C07H 19/048 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590168 | Parker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Laurie L. Parker (Minneapolis, Minnesota); Minervo Perez (Minneapolis, Minnesota) |
| ABSTRACT | The invention provides kinase substrates and methods comprising their use. |
| FILED | Tuesday, May 23, 2017 |
| APPL NO | 15/603273 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 7/06 (20130101) Original (OR) Class C07K 14/82 (20130101) C07K 14/715 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1205 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/02 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590171 | Silvas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jesus A. Silvas (Fayetteville, Georgia); Patricia V. Aguilar (Galveston, Texas); Vsevolod L. Popov (Galveston, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Jesus A. Silvas (Fayetteville, Georgia); Patricia V. Aguilar (Galveston, Texas); Vsevolod L. Popov (Galveston, Texas) |
| ABSTRACT | Provided herein are isolated exosomes. An exome can include a nonstructural (NSs) protein of a virus, a glycoprotein (Gn protein) of a virus, or a combination thereof. The virus is a member of the Order Bunyavirales, such as a member of the genus Phlebovirus. In one embodiment, the virus is Severe Fever with Thrombocytopenia Syndrome (SFTS) virus. Also provided are methods for making and using the exosomes described herein. |
| FILED | Friday, October 27, 2017 |
| APPL NO | 15/795729 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/42 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16043 (20130101) C12N 2760/12221 (20130101) C12N 2760/12222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590172 | Chan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Yee-peng Chan (Bethesda, Maryland); Christopher Broder (Silver Spring, Maryland) |
| ABSTRACT | This invention relates to soluble forms of F glycoprotein from Hendra and Nipah virus and to compositions comprising soluble forms of F glycoprotein from Hendra and Nipah virus. This invention further relates to soluble oligomers of F glycoprotein from Hendra and Nipah virus. This invention also relates to nucleic acids encoding soluble forms of F glycoprotein from Hendra and Nipah virus. This invention also relates to diagnostic and therapeutic methods using the soluble forms of F glycoprotein from Hendra and Nipah virus. Further, this invention relates to antibodies, including neutralizing antibodies, and to vaccines for the prevention, diagnosis and treatment of infection by Hendra and Nipah viruses. |
| FILED | Monday, August 06, 2018 |
| APPL NO | 16/055429 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/505 (20130101) A61K 2039/6031 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 16/1027 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/18222 (20130101) C12N 2760/18234 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590177 | Das Gupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Tapas Das Gupta (River Forest, Illinois); Ananda Chakrabarty (Villa Park, Illinois) |
| ABSTRACT | The present invention provides modified cupredoxin derived peptides with pharmacologic activity that have improved pharmacokinetic properties, and methods to use them to treat mammals suffering from various conditions related to the pharmacologic activities. Modifications of the cupredoxin derived peptides include amino acid sequence variants and structural derivations that increase the plasma half-life of the peptide, increase the specific activity of the pharmacologic activity, decrease immunogenicity, and decrease the biotransformation of the peptides. The modified cupredoxin derived peptides can be used in methods to treat mammals for cancer, conditions elated to inappropriate angiogenesis, viral and bacterial infections, and specifically HIV and malaria, conditions related to ephrin signaling, and to deliver cargo compounds, including diagnostic compounds, to cancer cells. |
| FILED | Thursday, May 03, 2018 |
| APPL NO | 15/969920 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/04 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/164 (20130101) Peptides C07K 7/00 (20130101) C07K 14/21 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/395 (20180101) Y02A 50/411 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590178 | Xin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hong Xin (New Orleans, Louisiana) |
| ASSIGNEE(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | Hong Xin (New Orleans, Louisiana) |
| ABSTRACT | Chimeric double peptide vaccines are disclosed, useful for inducing active immunity against Candida fungal infections. The chimeric peptide comprises an Fba peptide and an Met6 peptide, covalently linked to one another, with or without an intermediate linker. Fba and Met6 are cell surface components of Candida. When used as a vaccine, the chimeric double peptide vaccine induces stronger protective immunity against fungal infection than does the Fba peptide alone, or the Met6 peptide alone, or a mixture (not covalently linked) of the two peptides. |
| FILED | Friday, June 19, 2015 |
| APPL NO | 15/320225 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0002 (20130101) A61K 39/39575 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2039/575 (20130101) A61K 2039/6037 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/40 (20130101) Original (OR) Class C07K 16/14 (20130101) C07K 2317/24 (20130101) C07K 2319/40 (20130101) C07K 2319/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590181 | Boyden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Edward S. Boyden (Cambridge, Massachusetts); Yongku Peter Cho (Vernon, Connecticut); Nathan C. Klapoetke (Ashburn, Virginia); Amy S. Chuong (Ashburn, Virginia); Fei Chen (Cambridge, Massachusetts) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of mutant light-activated ion channels and variants thereof. |
| FILED | Saturday, April 18, 2015 |
| APPL NO | 14/653040 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/405 (20130101) C07K 14/705 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/5076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590182 | Lim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Wendell A. Lim (San Francisco, California); Leonardo Morsut (San Francisco, California); Kole T. Roybal (San Francisco, California); Justin Thomas Farlow (San Francisco, California); Satoshi Toda (San Francisco, California) |
| ABSTRACT | The present disclosure provides binding-triggered transcriptional switch polypeptides, nucleic acids comprising nucleotide sequences encoding the binding-triggered transcriptional switch polypeptides, and host cells genetically modified with the nucleic acids. The present disclosure also provides chimeric Notch receptor polypeptides, nucleic acids comprising nucleotide sequences encoding the chimeric Notch receptor polypeptides, and host cells transduced and/or genetically modified with the nucleic acids. The present disclosure provides transgenic organisms comprising a nucleic acid encoding a binding triggered transcriptional switch polypeptide and/or a chimeric Notch receptor polypeptide of the present disclosure. Binding triggered transcriptional switch polypeptides and chimeric Notch receptor polypeptides of the present disclosure are useful in a variety of applications, which are also provided. |
| FILED | Tuesday, February 23, 2016 |
| APPL NO | 15/543220 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 48/00 (20130101) Peptides C07K 14/71 (20130101) C07K 14/705 (20130101) Original (OR) Class C07K 14/715 (20130101) C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 19/00 (20130101) C07K 2317/22 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) C07K 2319/32 (20130101) C07K 2319/33 (20130101) C07K 2319/60 (20130101) C07K 2319/74 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/566 (20130101) G01N 33/6863 (20130101) G01N 33/6872 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590187 | Diskin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); THE ROCKEFELLER UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); The Rockefeller University (New York, New York) |
| INVENTOR(S) | Ron Diskin (Rehovot, Israel); Pamela J. Bjorkman (Pasadena, California); Michel C. Nussenzweig (New York, New York); Johannes Scheid (New York, New York) |
| ABSTRACT | Embodiments of the present invention are directed to compositions and methods for anti-HIV (anti-CD4 binding site) potent VRC01-like (PVL) antibodies targeted to gp120 having an amino acid substitution at a residue in the anti-CD4 binding site PVL antibody that is equivalent to Phe43 in CD4, these antibodies having improved potency and breadth. |
| FILED | Thursday, December 21, 2017 |
| APPL NO | 15/851432 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16111 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590190 | Rosenthal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Annexon, Inc. (South San Francisco, California) |
| ASSIGNEE(S) | Annexon, Inc. (South San Francisco, California) |
| INVENTOR(S) | Arnon Rosenthal (Woodside, California); Michael Leviten (Emerald Hills, California) |
| ABSTRACT | The present invention provides anti-C1q antibodies and methods of using the same. |
| FILED | Friday, January 04, 2019 |
| APPL NO | 16/239685 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0004 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/40 (20130101) C07K 2317/14 (20130101) C07K 2317/20 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/734 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) G01N 2333/4716 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590201 | Siegel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Richard M. Siegel (Bethesda, Maryland); Francoise Meylan (Bethesda, Maryland); Yun-Jeong Song (Bethesda, Maryland) |
| ABSTRACT | Methods and compositions for treating inflammatory or autoimmune diseases in a subject comprising blocking the interaction between DR3 and TL1A. In the methods of treating inflammatory or autoimmune disease, the inflammatory or autoimmune disease can be an autoimmune disease with a T cell component, including asthma, multiple sclerosis, rheumatoid arthritis, type 1 diabetes, graft versus host disease or inflammatory bowel disease. |
| FILED | Tuesday, January 16, 2018 |
| APPL NO | 15/872592 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/2875 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590373 | Thon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); VILNIUS UNIVERSITY (Vilnius, Lithuania) |
| ASSIGNEE(S) | BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); VILNIUS UNIVERSITY (Vilnius, Lithuania) |
| INVENTOR(S) | Jonathan N. Thon (Brookline, Massachusetts); Joseph E. Italiano (Chestnut Hill, Massachusetts); Linas Mazutis (Boston, Massachusetts); David A. Weitz (Boston, Massachusetts) |
| ABSTRACT | Systems and methods generating physiologic models that can produce functional biological substances are provided. In some aspects, a system includes a substrate and a first and second channel formed therein. The channels extend longitudinally and are substantially parallel to each other. A series of apertures extend between the first channel and second channel to create a fluid communication path passing through columns separating the channels that extends further along the longitudinal dimension than other dimensions. The system also includes a first source configured to selectively introduce into the first channel a first biological composition at a first channel flow rate and a second source configured to selectively introduce into the second channel a second biological composition at a second channel flow rate, wherein the first channel flow rate and the second channel flow rate create a differential configured to generate physiological shear rates within a predetermined range in the channels. |
| FILED | Monday, March 30, 2015 |
| APPL NO | 15/300070 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 2200/0605 (20130101) B01L 2200/0647 (20130101) B01L 2300/163 (20130101) B01L 2300/0681 (20130101) B01L 2300/0867 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0644 (20130101) C12N 2521/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590376 | Reich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Daniel H. Reich (Baltimore, Maryland); Fan Xu (Nanjing, China PRC); Ruogang Zhao (Baltimore, Maryland); Alan S. Liu (Baltimore, Maryland); Tristin Metz (Baltimore, Maryland); Yu Shi (Baltimore, Maryland) |
| ABSTRACT | A system and method for conditioning a tissue are provided. The system includes a substrate, a plurality of microwells formed in the substrate, and a microsphere associated with each of the plurality of microwells. The system also includes a pair of flexible pillars within each of the plurality of microwells. Each flexible pillar includes a first end bonded to a respective microwell and at least one flexible pillar has a second end bonded to the microsphere. The flexible pillars are configured to deflect when exposed to a magnetic field to controllably stretch microtissue spanning the flexible pillars. |
| FILED | Friday, November 20, 2015 |
| APPL NO | 15/528233 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/508 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/12 (20130101) C12M 23/20 (20130101) C12M 23/26 (20130101) C12M 25/00 (20130101) C12M 35/04 (20130101) C12M 35/06 (20130101) Original (OR) Class C12M 41/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590392 | Kotton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Darrell N. Kotton (Newton, Massachusetts); Katherine B. McCauley (Brookline, Massachusetts); Finn Hawkins (Boston, Massachusetts) |
| ABSTRACT | The technology described herein relates to methods and kits for directed differentation of primordial NKX2-1+ lung progenitors along proximal differentiation pathways into functional airway epithelial cells and airway organoids (“bronchospheres”) or along distal lineage pathways using modulation of Wnt signaling. Other aspects relate cell lines, methods, assays and kits comprising airway epithelial cells, and assays for diagnosing a disease that affects swelling of the bronchospheres, and/or for assessing genetic lesions and/or drugs for treating the the disease, where the disease is cystic fibrosis. Other aspects relate to personalized medicine and methods of treatment of cystic fibrosis using the airway epithelial cells. |
| FILED | Tuesday, January 09, 2018 |
| APPL NO | 15/865574 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0689 (20130101) C12N 5/0696 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2501/415 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590393 | Shusta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Eric V. Shusta (Madison, Wisconsin); Sean P. Palecek (Verona, Wisconsin); Ethan S. Lippmann (Madison, Wisconsin); Samira M. Azarin (Chicago, Illinois) |
| ABSTRACT | In one embodiment, the present invention is a method of creating a fully-human blood-brain barrier (BBB) model, comprising the steps of (a) obtaining a mixture of neural cells and brain microvascular endothelial cells (BMECs), wherein the neural cells and BMECs that comprise the mixture were produced from the differentiation of human pluripotent stem cells (hPSCs); (b) purifying BMECs from the mixture of neural cells and BMECs of step (a); and (c) co-culturing the purified BMECs with a cell type selected from the group consisting of pericytes, astrocytes and differentiated neural progenitor cells (NPCs), wherein a blood brain barrier model is created. |
| FILED | Monday, March 11, 2013 |
| APPL NO | 13/793466 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 5/0623 (20130101) C12N 5/0692 (20130101) C12N 5/0697 (20130101) Original (OR) Class C12N 2500/90 (20130101) C12N 2501/115 (20130101) C12N 2501/385 (20130101) C12N 2502/08 (20130101) C12N 2502/088 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590394 | Steinmetz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Nicole Steinmetz (Cleveland, Ohio); Daniel Popkin (Cleveland, Ohio) |
| ABSTRACT | A method of non-covalently loading a plant picornavirus is described. The method includes contacting a plant picornavirus in solution with a molar excess of a cargo molecule to load the plant picornavirus with the cargo molecule, and then purifying the loaded plant picornavirus. Examples of cargo molecules include imaging agents, antitumor agents, and antiviral agents. Loaded plant picornaviruses prepared in this manner can be used to delivering cargo molecule to cells. |
| FILED | Tuesday, February 18, 2014 |
| APPL NO | 14/769247 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/473 (20130101) A61K 33/24 (20130101) A61K 35/76 (20130101) A61K 47/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2770/32041 (20130101) C12N 2770/32042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590409 | Beebe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Salus Discovery LLC (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David J. Beebe (Monona, Wisconsin); David J. Guckenberger, Jr. (Oconomowoc, Wisconsin); Hannah M. Pezzi (New Berlin, Wisconsin) |
| ABSTRACT | A method and a device are provided for facilitating the disaggregation of a plurality of solid phase substrate as the plurality of solid phase substrate are transferred from a first location to a second location. A plurality of solid phase substrate are deposited at the first location and a plurality of particles are added to the plurality of solid phase substrate. A force is generated to draw the plurality of solid phase substrate from the first location to a second location. The plurality of particles causes clumps of the plurality of solid phase substrate to break apart as the plurality of solid phase substrate are moved in response to the force. |
| FILED | Tuesday, December 06, 2016 |
| APPL NO | 15/370375 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1013 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 2523/303 (20130101) C12Q 2563/143 (20130101) C12Q 2563/149 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54333 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590417 | Guo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Peixuan Guo (Dubin, Ohio); Fengmei Pi (Columbus, Ohio); Hui Li (San Francisco, California); Shaoying Wang (Middlesex, New Jersey) |
| ABSTRACT | Disclosed herein are compositions comprising extracellular vesicles, such as exosomes, displaying an RNA nanoparticle on its surface. The RNA nanoparticle can target the extracellular vesicle to a given cell via a targeting moiety. The extracellular vesicle can also comprise a functional moiety, which can be used in treatment or diagnostics. |
| FILED | Friday, October 05, 2018 |
| APPL NO | 16/152911 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 9/513 (20130101) A61K 9/1273 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/51 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590418 | Kay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mark A. Kay (Los Altos, California); Anton McCaffrey (Pacifica, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Mark A. Kay (Los Altos, California); Anton McCaffrey (Pacifica, California) |
| ABSTRACT | Methods and compositions are provided for modulating, e.g., reducing, viral coding sequence expression in mammals and mammalian cells. In the subject methods, an effective amount of an RNAi agent, e.g., an interfering ribonucleic acid (such as an siRNA or shRNA) or a transcription template thereof, e.g., a DNA encoding an shRNA, is introduced into a target cell, e.g., by being administered to a mammal that includes the target cell, e.g., via a hydrodynamic administration protocol. Also provided are RNAi agent pharmaceutical preparations for use in the subject methods. The subject methods and compositions find use in a variety of different applications, including academic and therapeutic applications. |
| FILED | Friday, September 27, 2002 |
| APPL NO | 10/259226 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/075 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/70 (20130101) A61K 38/00 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1131 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/53 (20130101) C12N 2310/111 (20130101) Technologies for Adaptation to Climate Change Y02A 50/463 (20180101) Y02A 50/465 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590419 | Morrisey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Edward E. Morrisey (Newtown Square, Pennsylvania) |
| ABSTRACT | The invention relates to compostions and methods for promoting cellular proliferation and de-differentiation of cells into stem cells to foster tissue regeneration. Specifically, the invention relates to transiently administering a microRNA (miR) or its mimic for promoting cardiomyocyte proliferation and cardiac regeneration. |
| FILED | Friday, May 15, 2015 |
| APPL NO | 15/311765 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2227/105 (20130101) A01K 2267/0375 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/7105 (20130101) A61K 48/0058 (20130101) A61K 48/0075 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 5/0662 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2320/32 (20130101) C12N 2320/35 (20130101) C12N 2501/65 (20130101) C12N 2510/00 (20130101) C12N 2740/15043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590433 | Stamatoyannopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | George Stamatoyannopoulos (Seattle, Washington); John Stamatoyannopoulos (Seattle, Washington) |
| ABSTRACT | Provided herein are methods for identifying high potency genomic insulator elements that can be used in a vector composition e.g., that are useful for preventing unwanted expression of neighboring genes, such as proto-oncogenes, when administered to a subject in need thereof. Also provided herein are methods for treating disease and methods for administering a nucleic acid to a subject using such vectors. |
| FILED | Friday, March 13, 2015 |
| APPL NO | 15/126115 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/141 (20130101) C12N 2740/15043 (20130101) C12N 2740/16043 (20130101) C12N 2830/40 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590435 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadlephia, Pennsylvania) |
| INVENTOR(S) | Guangping Gao (Westborough, Massachusetts); James M. Wilson (Philadelphia, Pennsylvania); Mauricio R. Alvira (Philadelphia, Pennsylvania) |
| ABSTRACT | Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. |
| FILED | Wednesday, September 26, 2018 |
| APPL NO | 16/142921 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/761 (20130101) A61K 38/45 (20130101) A61K 38/177 (20130101) A61K 38/4846 (20130101) A61K 48/00 (20130101) Peptides C07K 14/005 (20130101) C07K 14/705 (20130101) C07K 14/755 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/644 (20130101) C12N 9/1018 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 15/8645 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14152 (20130101) C12N 2830/008 (20130101) C12N 2830/48 (20130101) C12N 2830/85 (20130101) Enzymes C12Y 201/03003 (20130101) C12Y 304/21021 (20130101) C12Y 304/21022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590452 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SEOUL INDUSTRY COOPERATION FOUNDATION (Seoul, South Korea) |
| ASSIGNEE(S) | UNIVERSITY OF SEOUL INDUSTRY COOPERATION FOUNDATION (Seoul, South Korea) |
| INVENTOR(S) | Jong-Bum Lee (Seoul, South Korea); Jae-Sung Lee (Namyangju-si, South Korea) |
| ABSTRACT | This invention relates to DNA-Mn hybrid particles and a method of manufacturing the same, the method including producing a circular DNA template for replication and forming particles in which DNA and Mn are bound to each other using Mn during the synthesis of a new strand of DNA from the circular DNA template for replication using a DNA polymerase, thus promoting the activity of the DNA polymerase using the coenzyme function of Mn and broadening the range of application fields of DNA as a biomaterial. |
| FILED | Wednesday, December 20, 2017 |
| APPL NO | 15/849006 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 23/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class Enzymes C12Y 207/07007 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590465 | Vogelstein et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Jian Wu (Baltimore, Maryland) |
| ABSTRACT | Assays can be used to detect mutations found in neoplasms of the pancreas, as well as for other neoplasms and other uses. Nucleic acids can be captured from body fluids such as cyst fluids. Thousands of oligonucleotides can be synthesized in parallel, amplified and ligated together. The ligated products can be further amplified. The amplified, ligated products are used to capture complementary DNA sequences, which can be analyzed, for example by massively parallel sequencing. |
| FILED | Tuesday, May 30, 2017 |
| APPL NO | 15/608243 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2563/131 (20130101) C12Q 2563/131 (20130101) C12Q 2563/149 (20130101) C12Q 2563/149 (20130101) C12Q 2565/518 (20130101) C12Q 2565/518 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590473 | Meyerson et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Matthew Meyerson (Boston, Massachusetts); Ganesh M. Shankar (Boston, Massachusetts); Joshua M. Francis (Cambridge, Massachusetts); Daniel P. Cahill (Boston, Massachusetts); Mikael L. Rinne (Boston, Massachusetts) |
| ABSTRACT | Provided are systems, kits, and methods for the quantitative detection of single nucleotide polymorphisms or variants to identify malignant neoplasms. The methods include use of modified oligonucleotide blockers with peptide nucleic acid backbones that hybridize to and block logarithmic amplification of the wild-type alleles of a target, and incorporation of locked nucleic acids into probes that are complementary to a mutant allele of the target sequence to increase specificity. The methods include detection of variants in sequences with high GC content and/or low complexity, such as the TERT promoter, IDH1, BRAF, NRAS, GNAQ, GNA11 and H3F3 A gene variants. The methods include sensitive detection and staging of cancers with low cellularity, and can be used intraoperatively such as for glioma, or to detect cell-free circulating tumor DNA, such as for melanoma. |
| FILED | Tuesday, December 22, 2015 |
| APPL NO | 15/538382 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6853 (20130101) Original (OR) Class C12Q 1/6853 (20130101) C12Q 2525/107 (20130101) C12Q 2525/107 (20130101) C12Q 2525/107 (20130101) C12Q 2525/113 (20130101) C12Q 2525/113 (20130101) C12Q 2527/107 (20130101) C12Q 2527/107 (20130101) C12Q 2531/113 (20130101) C12Q 2531/113 (20130101) C12Q 2531/113 (20130101) C12Q 2545/114 (20130101) C12Q 2545/114 (20130101) C12Q 2545/114 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591353 | Caucci et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of The University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of The University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Luca Caucci (Tucson, Arizona); Harrison Barrett (Tucson, Arizona) |
| ABSTRACT | The present invention provides methods and systems for manipulating radiance data obtained from a radiance sensor that includes a lenslet array and a photodetector array, where the manipulation of the radiance data uses one or more algorithms or mathematical transformations applied by a software program. Manipulating the measured radiance data computationally produces the same optical effects of a desired optical system without having to insert the optical system into the optical path of the electromagnetic radiation. The manipulated radiance data is then used to generate an image. |
| FILED | Sunday, February 10, 2019 |
| APPL NO | 16/271829 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) Original (OR) Class G01J 1/0437 (20130101) G01J 2001/444 (20130101) G01J 2001/448 (20130101) Optical Elements, Systems, or Apparatus G02B 27/0961 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591418 | Ma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri); Clemson University (Clemson, South Carolina) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri); Clemson University (Clemson, South Carolina) |
| INVENTOR(S) | Yinfa Ma (Rolla, Missouri); Honglan Shi (Rolla, Missouri); Qingbo Yang (Rolla, Missouri); Hai Xiao (Clemson, South Carolina) |
| ABSTRACT | A pH micro-probe, a temperature micro-probe, and an immuno-based micro-probe each include a shaft for transmuting an input light signal and a tip for inserting into a cell or other substance for measuring pH, temperature, and/or antigens. The pH micro-probe and the temperature micro-probe each include a luminescent material positioned on the tip of the micro-probe. The light signal excites the luminescent material so that the luminescent material emits a luminescent light signal. The luminescent light signal has a property value dependent on the pH or temperature being measured and reflects back through the shaft for being measured by a light signal measuring device. The immuno-based micro-probe includes a reflective material that has an effective refractive index dependent on the number of antigen-antibody bonds present on the reflective material. |
| FILED | Monday, December 11, 2017 |
| APPL NO | 15/837597 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/76 (20130101) G01N 21/80 (20130101) G01N 21/645 (20130101) G01N 21/6428 (20130101) G01N 21/7703 (20130101) Original (OR) Class G01N 31/221 (20130101) G01N 2021/772 (20130101) G01N 2021/6434 (20130101) G01N 2021/7786 (20130101) G01N 2201/08 (20130101) G01N 2201/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591458 | Parker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Kevin Kit Parker (Cambridge, Massachusetts); Johan Ulrik Lind (Boston, Massachusetts); Jennifer Ann Lewis (Cambridge, Massachusetts); Joost Johan Vlassak (Lexington, Massachusetts); Hongyan Yuan (Cangzhou, China PRC); Travis Alexander Busbee (Somerville, Massachusetts); Ian Perkins (Bridgewater, Massachusetts); Christophe Chantre (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments described herein are directed to devices for supporting growth of anisotropic muscle tissue layers and in vitro readout and quantification of force generated by the tissue layers using one or more strain-sensing elements integrated into the device. Embodiments also include multiplexed apparatuses of multiple independent devices, methods of fabricating the devices and apparatuses, and methods of using the devices and apparatuses. |
| FILED | Wednesday, February 18, 2015 |
| APPL NO | 15/116258 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/053 (20130101) A61B 5/4519 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591471 | Takada et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yoshikazu Takada (Davis, California); Yoko Takada (Davis, California); Masaaki Fujita (Osaka, Japan) |
| ABSTRACT | The present invention relates to the discovery that a secretory phospholipase A2 (sPLA2-IIA) plays an active role in mediating cellular signaling leading to an inflammatory response or cell proliferation by way of its specific binding with integrin β at site 2 of integrin β. More specifically, the invention provides a method for identifying inhibitors of inflammatory or proliferative signaling by screening for compounds that interrupt the specific binding of sPLA2 and integrin β at site 2. The invention also provides the novel use of a substance that suppresses the specific binding between sPLA2 and site 2 of integrinβ for the purpose of treating or preventing a condition involving an undesired inflammatory response or cell proliferation. |
| FILED | Thursday, November 12, 2015 |
| APPL NO | 15/526573 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/177 (20130101) Peptides C07K 14/70546 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/52 (20130101) G01N 33/533 (20130101) G01N 33/566 (20130101) G01N 33/582 (20130101) G01N 33/5306 (20130101) G01N 33/54306 (20130101) Original (OR) Class G01N 2333/92 (20130101) G01N 2333/70546 (20130101) G01N 2500/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591484 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); University of Maryland College Park (College Park, Maryland) |
| INVENTOR(S) | Hui Zhang (Ellicott City, Maryland); Shuang Yang (Ellicott City, Maryland) |
| ABSTRACT | Highly specific and novel methods for analyzing glycans and proteoglycans are provided. The present invention provides glycan-reactive isobaric Aldehyde-Reactive Tags (iARTs) and the quantification of iARTs-labeled glycans by tandem mass spectrometry. The iARTs have an amine as an active group to react with aldehyde at the reducing end of glycans through reductive amination and demonstrated complete labeling. Due to the isobaric nature of the iARTs, differentially labeled glycans do not differ in mass, and quantitative information is provided by the isotope-encoded reporter ions generated from MS/MS or MS3 spectra. Quantitative information is thus derived from signal of the reporter ions on same precursor. Uses of the information generated by the inventive methods for diagnosis and treatment are also disclosed. |
| FILED | Thursday, March 15, 2018 |
| APPL NO | 15/922534 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 237/22 (20130101) Polysaccharides; Derivatives Thereof C08B 37/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) G01N 33/58 (20130101) Original (OR) Class G01N 33/6848 (20130101) G01N 2400/00 (20130101) G01N 2560/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591495 | Ayyub et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); CHILDREN'S NATIONAL MEDICAL CENTER (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); Children's National Medical Center (Washington, District of Columbia) |
| INVENTOR(S) | Omar Bilal Ayyub (Potomac, Maryland); Adam Michael Behrens (Olney, Maryland); Peter Kofinas (North Bethesda, Maryland); Marshall Lynn Summar, II (Washington, District of Columbia); Juan Manuel Cabrera-Luque (Rockville, Maryland); Gary Cunningham (Washington, District of Columbia) |
| ABSTRACT | The present disclosure relates to a biosensor capable of measuring the total concentration of one or a plurality of ammonia or ammonium ions with the use of indophenol reagents in the presence of an ionomer. In some embodiments, the biosensor comprises a perflurinated membrane that comprises an ionomer in contact with an alkali buffer in a vessel configured to receive a sample, such as whole blood. The disclosure also relates to a method of detecting or quantifying the ammonia or ammonium ion concentration in whole blood in a point of care bio sensor without reliance on gas chromatography or any measurement that takes more than about twenty minutes. |
| FILED | Wednesday, April 27, 2016 |
| APPL NO | 15/570269 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/216 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/00 (20180101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2200/16 (20130101) B01L 2300/0636 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 33/84 (20130101) Original (OR) Class G01N 33/6806 (20130101) G01N 2021/775 (20130101) G01N 2021/7759 (20130101) G01N 2800/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591566 | Kobayashi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Naoharu Kobayashi (Minneapolis, Minnesota); Djaudat Idiyatullin (Minneapolis, Minnesota); Michael Garwood (Minneapolis, Minnesota) |
| ABSTRACT | A method for acquiring magnetic resonance imaging data from a subject. The method includes performing a series of radio frequency pulses formed of individual RF pulses applied with a constant time interval between each of the individual RF pulses to form a consistent magnetic field about at least of a region of interest in the subject, where the RF pulse has a flip angle of less than 30 degrees. The method also includes performing phase encoding gradients to achieve spatial encoding and performing an imaging acquisition process over an acquisition window to acquire imaging data. The method further includes performing phase encoding rephasing gradients and repeating the preceding steps such that a time between a center of the acquisition window and a center of a first RF pulse in a first RF pulse in a repetition of the RF pulses is equal to the constant pulse interval. |
| FILED | Friday, October 13, 2017 |
| APPL NO | 16/341677 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/243 (20130101) G01R 33/5613 (20130101) Original (OR) Class G01R 33/56563 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591570 | Ooi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Melvyn B. Ooi (College Station, Texas); Julian Maclaren (Menlo Park, California); Murat Aksoy (Menlo Park, California); Roland Bammer (Palo Alto, California); Ronald D. Watkins (Redwood City, California) |
| ABSTRACT | Wireless markers having predetermined relative positions with respect to each other are employed for motion tracking and/or correction in magnetic resonance (MR) imaging. The markers are inductively coupled to the MR receive coil(s). The correspondence between marker signals and markers can be determined by using knowledge of the marker relative positions in various ways. The marker relative positions can be known a priori, or can be obtained from a preliminary scan. This approach is applicable for imaging (both prospective and retrospective motion correction), spectroscopy, and/or intervention. |
| FILED | Tuesday, December 17, 2013 |
| APPL NO | 14/109403 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0037 (20130101) A61B 5/055 (20130101) A61B 5/1114 (20130101) A61B 5/1127 (20130101) A61B 5/1128 (20130101) A61B 5/6803 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/58 (20130101) G01R 33/56509 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591870 | Brooker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CellOptic, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | CellOptic, Inc. (Rockville, Maryland) |
| INVENTOR(S) | Gary Brooker (Rockville, Maryland); Nisan Siegel (Silver Spring, Maryland) |
| ABSTRACT | Techniques to improve image quality in holography utilizing lenses made from materials with non-quantized anisotropic electromagnetic properties, such as birefringent materials, to advantageously split an incoming beam of light into two coincident beams with different focal lengths that interfere with one another and thus create holograms free of electro-optical or pixelated devices are disclosed for microscopy and other applications. The use of thin birefringent lenses and single crystal alpha-BBO lenses are introduced. Corresponding systems, methods and apparatuses are described. |
| FILED | Friday, May 05, 2017 |
| APPL NO | 15/588096 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/13 (20130101) Optical Elements, Systems, or Apparatus G02B 1/02 (20130101) G02B 3/08 (20130101) G02B 5/3016 (20130101) G02B 5/3083 (20130101) G02B 21/0056 (20130101) G02B 21/0068 (20130101) Holographic Processes or Apparatus G03H 1/0005 (20130101) G03H 1/06 (20130101) G03H 1/041 (20130101) Original (OR) Class G03H 1/0443 (20130101) G03H 1/0866 (20130101) G03H 2001/005 (20130101) G03H 2001/0447 (20130101) G03H 2001/0452 (20130101) G03H 2222/24 (20130101) G03H 2223/17 (20130101) G03H 2223/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592310 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Peter Chao-yuan Li (McLean, Virginia); Jeffrey R. Collmann (Washington, District of Columbia); Jane W. Blake (Alexandria, Virginia); Mark G. Polyak (Alexandria, Virginia); James M. Wilson (Alexandria, Virginia); Jae In Yoon (Centreville, Virginia); Manabu Torii (Falls Church, Virginia); Carla S. Thomas (Bodega Bay, California) |
| ABSTRACT | A system and method involves detecting operational social disruptive events on a global scale, modeling data in conjunction with linguistics analysis to establish responsive actions, and generating visualization and executing models for communicating information. |
| FILED | Wednesday, April 18, 2018 |
| APPL NO | 15/955823 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) Original (OR) Class G06F 16/9535 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592687 | Kapadia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); United States of America as Represented by The Secretary of The Navy (Arlington, Virginia) |
| INVENTOR(S) | Apu Kapadia (Bloomington, Indiana); Robert E. Templeman (Bloomington, Indiana); David Crandall (Bloomington, Indiana); Mohammed Korayem (Bloomington, Indiana) |
| ABSTRACT | A method and device for classifying collected images. The method and device include instructions to compare a captured image to a known set of images to determine the location depicted therein; and applying a classification upon the image based upon the determined location depicted therein and whether the determined location indicates that the image has the potential to depict privacy sensitive information. |
| FILED | Thursday, October 09, 2014 |
| APPL NO | 15/029559 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/51 (20190101) G06F 16/5838 (20190101) G06F 16/5854 (20190101) G06F 16/5862 (20190101) G06F 16/5866 (20190101) G06F 21/6245 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/78 (20130101) G06K 9/00664 (20130101) G06K 9/00771 (20130101) G06K 9/4671 (20130101) G06K 9/6202 (20130101) G06K 9/6267 (20130101) G06K 9/6297 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593040 | Zouridakis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | George Zouridakis (Houston, Texas) |
| ABSTRACT | Provided herein are digital-implemented methods for performing simultaneous analyses on an object on the skin of an animal body, for example, a human, to classify the object as a skin cancer, an ulcer or neither. The analyses are performed simultaneously on a hand-held imaging device. |
| FILED | Tuesday, February 19, 2019 |
| APPL NO | 16/278946 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0077 (20130101) A61B 5/444 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 2209/05 (20130101) G06K 2209/053 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10024 (20130101) G06T 2207/20081 (20130101) G06T 2207/30088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593349 | Park |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
| INVENTOR(S) | Chung Hyuk Park (McLean, Virginia) |
| ABSTRACT | A system and method for emotional interaction. The system includes a robot that uses behavioral analysis automation to provide treatment and assessment of emotional communication and social skills for children with autism. The system generates a dataset including speech signals of one or more speakers, and assigns at least one of a set of labels to each of the speech signals for the one or more speakers. The set of labels includes at least three levels of emotional dimensions, the emotional dimensions include at least activation, valence, and dominance, and the at least three levels of emotional dimensions include a high state, a neutral state, and a low state. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/625747 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 17/2785 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/02 (20130101) G10L 15/22 (20130101) G10L 15/063 (20130101) G10L 15/1807 (20130101) G10L 15/1815 (20130101) G10L 25/63 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10588761 | Holt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Brian Mueller Holt (Topanga, California); Sujee Jeyapalina (Salt Lake City, Utah); Roy Drake Bloebaum (Salt Lake City, Utah); Kent Nelson Bachus (Salt Lake City, Utah) |
| ABSTRACT | An abutment system for operatively coupling an implant stem to an exo-prosthesis. The abutment system includes a plurality of interlocking sleeve elements that are operatively coupled to an implant stem positioned within a prepared site of a selected bone. The interlocking sleeve elements of the abutment system are selectively removable and replaceable. |
| FILED | Friday, December 08, 2017 |
| APPL NO | 15/835954 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/78 (20130101) Original (OR) Class A61F 2/2814 (20130101) A61F 2002/502 (20130101) A61F 2002/3055 (20130101) A61F 2002/5083 (20130101) A61F 2002/7887 (20130101) A61F 2220/0041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589045 | Kinsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Texas System (Austin, Texas); United States Government, as represented by the Secretary of the Army (Ft. Detrick, Maryland); University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Kinsky (League City, Texas); Rich Branson (Cincinnati, Ohio); George Kramer (Galveston, Texas); Muzna Khan (Webster, Texas); Jay Johanningman (Cincinnati, Ohio); Jose Salinas (San Antonio, Texas); Nehemiah Liu (San Antonio, Texas) |
| ABSTRACT | A system for assessing lung function in a patient is enclosed. The oxygen delivery system in the system (e.g., a ventilator or portable standalone system) preferably includes an oximeter sensor for receiving SpO2 from a patient. The assessing lung function in a patient includes an FiO2 adjust algorithm operable in logic circuitry in the ventilator that can control an oxygen fraction FiO2 provided to the patient in a closed loop fashion. In a preferred example, the algorithm controls FiO2 using the SpO2, but also displays a ratio of SpO2-to FiO2 (S/CLCF) as a function of time. One or more S/CLCF ratio threshold may be used to allow the clinician and/or the algorithm to understand a degree of lung injury, and to allow the algorithm to adjust FiO2 appropriately. Preferably, the algorithm keeps SpO2 to a range of 88-95%. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/725172 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/08 (20130101) A61B 5/4836 (20130101) A61B 5/4839 (20130101) A61B 5/14551 (20130101) Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 10/04 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/04 (20130101) A61M 16/06 (20130101) A61M 16/024 (20170801) Original (OR) Class A61M 16/0051 (20130101) A61M 16/0057 (20130101) A61M 16/125 (20140204) A61M 16/1005 (20140204) A61M 2202/0007 (20130101) A61M 2202/0208 (20130101) A61M 2202/0208 (20130101) A61M 2205/18 (20130101) A61M 2205/502 (20130101) A61M 2205/3303 (20130101) A61M 2205/3569 (20130101) A61M 2230/005 (20130101) A61M 2230/205 (20130101) A61M 2230/205 (20130101) A61M 2240/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589087 | Tyler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wicab, Inc. (Middleton, Wisconsin) |
| ASSIGNEE(S) | WICAB, INC. (Middleton, Wisconsin) |
| INVENTOR(S) | Mitchell Eugene Tyler (Madison, Wisconsin); Yuri Petrovich Danilov (Middleton, Wisconsin); Paul Bach-y-Rita (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to systems and methods for management of brain and body functions and sensory perception. For example, the present invention provides systems and methods of sensory substitution and sensory enhancement (augmentation) as well as motor control enhancement. The present invention also provides systems and methods of treating diseases and conditions, as well as providing enhanced physical and mental health and performance through sensory substitution, sensory enhancement, and related effects. |
| FILED | Tuesday, April 21, 2015 |
| APPL NO | 14/692419 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/112 (20130101) A61B 5/486 (20130101) A61B 5/0492 (20130101) A61B 5/682 (20130101) A61B 5/686 (20130101) A61B 5/726 (20130101) A61B 5/1116 (20130101) A61B 5/1123 (20130101) A61B 5/1124 (20130101) A61B 5/4005 (20130101) A61B 5/4023 (20130101) A61B 5/4047 (20130101) A61B 5/4528 (20130101) A61B 5/6803 (20130101) A61B 5/7225 (20130101) A61B 5/7455 (20130101) A61B 5/7475 (20130101) A61B 5/14553 (20130101) A61B 2562/046 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0548 (20130101) Original (OR) Class A61N 1/36025 (20130101) A61N 1/36082 (20130101) A61N 1/36103 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/012 (20130101) G06F 3/015 (20130101) G06F 3/016 (20130101) G06F 3/038 (20130101) G06F 3/0383 (20130101) G06F 3/03547 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589124 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Joseph Smith (Tempe, Arizona); Barry O'Brien (Chandler, Arizona); Yong-Kyun Lee (Chandler, Arizona); Edward Bawolek (Chandler, Arizona); Jennifer Blain Christen (Chandler, Arizona); Michael Goryll (Mesa, Arizona); Jitendran Muthuswamy (Chandler, Arizona); George R. Kunnen (Chandler, Arizona); David Allee (Phoenix, Arizona) |
| ABSTRACT | Systems and methods for stimulating neural tissue are disclosed. An array of optically emissive pixels is configured to deliver light to the neural tissue of a subject. Individual pixels within the array can be addressed to selectively illuminate a portion of the neural tissue when a neurological event occurs. The system can also include an array of microelectrodes in electrical communication with the array of pixels and a power source. A biocompatible substrate can be used to support the microelectrodes pixels, and the power source. A microelectrode circuit and a pixel circuit can also be supported by the biocompatible substrate. |
| FILED | Tuesday, January 13, 2015 |
| APPL NO | 15/111952 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/04001 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0601 (20130101) A61N 5/0622 (20130101) Original (OR) Class A61N 2005/0612 (20130101) A61N 2005/0626 (20130101) A61N 2005/0653 (20130101) A61N 2005/0663 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589237 | Colling, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Arthur K. Colling, Jr. (Monson, Massachusetts); Benjamin E. Bishop (South Glastonbury, Connecticut); Allison B. Thomas (Hampden, Massachusetts) |
| ABSTRACT | A discharge system includes a mixing vessel and a feedstock input in fluid communication with the mixing vessel. A solvent input is in fluid communication with the mixing vessel. A discharge output is in fluid communication with an outlet of the mixing vessel to discharge effluent. A method for generating turbulence on a liquid surface within a discharge system includes supplying a mixing vessel with feedstock fluid and solvent fluid to generate a liquid mixture and a gas pocket in the mixing vessel. The method includes supplying an impinging solvent fluid through a nozzle extending from a first end of the mixing vessel to generate a roiling surface at an interface between the gas pocket and the liquid mixture and permit uptake of gas from the gas pocket into the liquid mixture. |
| FILED | Friday, January 15, 2016 |
| APPL NO | 14/997287 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/04248 (20130101) B01F 3/04496 (20130101) B01F 3/04737 (20130101) B01F 5/0057 (20130101) B01F 5/0682 (20130101) Original (OR) Class Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/08 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/04 (20130101) F01N 13/12 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589316 | Curran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Seamus Curran (Pearland, Texas); Kang-Shyang Liao (Houston, Texas); Nigel Alley (Houston, Texas); Amrita Haldar (Houston, Texas); Alexander Wang (Houston, Texas); Renat Tatarin (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Seamus Curran (Pearland, Texas); Kang-Shyang Liao (Houston, Texas); Nigel Alley (Houston, Texas); Amrita Haldar (Houston, Texas); Alexander Wang (Houston, Texas); Renat Tatarin (Houston, Texas) |
| ABSTRACT | A process of fabricating the waterproof coating may include selecting a substrate, utilizing a sol-gel comprising a silane or silane derivative and metal oxide precursor to coat the substrate, and optionally coating the substrate with a hydrophobic chemical agent and/or other chemical agents to create a surface with nanoscopic or microscopic features. The process may utilize an all solution process or controlled environment for fabricating self-cleaning and waterproof coating that prevent wetting or staining of a substrate, or may utilize a controlled environment. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 15/609443 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/185 (20130101) B05D 5/083 (20130101) Original (OR) Class B05D 2350/60 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 13/503 (20130101) D06M 13/507 (20130101) D06M 13/513 (20130101) D06M 13/517 (20130101) D06M 23/00 (20130101) D06M 2200/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589829 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Xiaobo Tan (East Lansing, Michigan); Feitian Zhang (Greenbelt, Maryland); Jianxun Wang (Plainsboro, New Jersey); John Thon (Mason, Michigan) |
| ABSTRACT | A robotic submersible includes a housing having a body and a tail. In another aspect, a pump and a pump tank adjust the buoyancy of a submersible housing. In a further aspect, a first linear actuator controls the pump and/or a buoyancy, and/or a second linear actuator controls a position of a battery and/or adjusts a center of gravity. Another aspect includes a pump and at least one linear actuator that control gliding movements of the housing. In still a further aspect, a motor couples a tail with a body, such that the motor controls the movements of the tail to create a swimming movement. Moreover, an additional aspect provides a controller selectively operating the pump, first actuator, second actuator, and motor to control when swimming and gliding movements occur. |
| FILED | Thursday, July 20, 2017 |
| APPL NO | 15/655072 |
| ART UNIT | 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) Original (OR) Class B63G 2008/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589878 | Veto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Christopher C. Veto (Long Beach, California); Gary David Grayson (Issaquah, Washington); Victor John Barackman (Costa Mesa, California) |
| ABSTRACT | A grid stiffened structure which includes a wall which extends in a direction transverse relative to a plane and an elongated rib connected along an elongated dimension of the rib to the wall such that the elongated rib extends along the wall and forms an angle with an axis which extends in a direction perpendicular to the plane. The elongated rib defines a free sidewall which extends from the wall positioned on a first side of the elongated rib and extends in a direction about the elongated rib and transverse to the elongated dimension to the wall positioned on a second side of the elongated rib. The wall and the elongated rib are constructed of a plurality of layers of material which extend in a direction transverse to the axis. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/375640 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Cosmonautics; Vehicles or Equipment Therefor B64G 1/402 (20130101) Original (OR) Class Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/08 (20130101) F17C 13/008 (20130101) F17C 2201/0147 (20130101) F17C 2203/012 (20130101) F17C 2209/21 (20130101) F17C 2270/0194 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589983 | Kub et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as Represented by the Secretary of the Navy (Arlington, Virginia); The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Francis J. Kub (Arnold, Maryland); Karl D. Hobart (Alexandria, Virginia); Eugene A. Imhoff (Washington, District of Columbia); Rachael L. Myers-Ward (Spriingfield, Virginia); Eugene Cook (Melrose, Massachusetts); Jonathan Bernstein (Medfield, Massachusetts); Marc Weinberg (Needham, Massachusetts) |
| ABSTRACT | Electromechanical device structures are provided, as well as methods for forming them. The device structures incorporate at least a first and second substrate separated by an interface material layer, where the first substrate comprises an anchor material structure and at least one suspended material structure, optionally a spring material structure, and optionally an electrostatic sense electrode. The device structures may be formed by methods that include providing an interface material layer on one or both of the first and second substrates, bonding the interface materials to the opposing first or second substrate or to the other interface material layer, followed by forming the suspended material structure by etching. |
| FILED | Thursday, September 07, 2017 |
| APPL NO | 15/698604 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0072 (20130101) Original (OR) Class B81B 7/0016 (20130101) B81B 7/0019 (20130101) B81B 2201/0235 (20130101) B81B 2201/0242 (20130101) B81B 2201/0271 (20130101) B81B 2203/04 (20130101) B81B 2203/0109 (20130101) B81B 2203/0118 (20130101) B81B 2203/0127 (20130101) B81B 2203/0163 (20130101) B81B 2203/0307 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00666 (20130101) B81C 2201/0132 (20130101) B81C 2203/036 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/56 (20130101) G01C 19/5621 (20130101) G01C 19/5656 (20130101) G01C 19/5783 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590172 | Chan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Yee-peng Chan (Bethesda, Maryland); Christopher Broder (Silver Spring, Maryland) |
| ABSTRACT | This invention relates to soluble forms of F glycoprotein from Hendra and Nipah virus and to compositions comprising soluble forms of F glycoprotein from Hendra and Nipah virus. This invention further relates to soluble oligomers of F glycoprotein from Hendra and Nipah virus. This invention also relates to nucleic acids encoding soluble forms of F glycoprotein from Hendra and Nipah virus. This invention also relates to diagnostic and therapeutic methods using the soluble forms of F glycoprotein from Hendra and Nipah virus. Further, this invention relates to antibodies, including neutralizing antibodies, and to vaccines for the prevention, diagnosis and treatment of infection by Hendra and Nipah viruses. |
| FILED | Monday, August 06, 2018 |
| APPL NO | 16/055429 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/505 (20130101) A61K 2039/6031 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 16/1027 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/18222 (20130101) C12N 2760/18234 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590181 | Boyden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Edward S. Boyden (Cambridge, Massachusetts); Yongku Peter Cho (Vernon, Connecticut); Nathan C. Klapoetke (Ashburn, Virginia); Amy S. Chuong (Ashburn, Virginia); Fei Chen (Cambridge, Massachusetts) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of mutant light-activated ion channels and variants thereof. |
| FILED | Saturday, April 18, 2015 |
| APPL NO | 14/653040 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/405 (20130101) C07K 14/705 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/5076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590241 | Wetzel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Eric D. Wetzel (Baltimore, Maryland); Emil Jose Sandoz-Rosado (Baltimore, Maryland); Todd David Beaudet (Aberdeen, Maryland); Radhakrishnan Balu (Columbia, Maryland); John Joseph La Scala (Wilmington, Delaware); Dominika Nini Lastovickova (Aberdeen, Maryland) |
| ABSTRACT | A family of new and novel molecules for mechanically superior two-dimensional (2D) polymers is described herein. By combining stiff carbon-containing cyclic polymer nodal units with more compliant linear polymer bridge units in an ordered, 2D repeating molecular structure it is possible to tailor the mechanical properties of 2D polymers and their assemblies to provide high stiffness, strength, and toughness. Furthermore, the inherent dimensionality of 2D polymers and their ability to be stacked into ordered and chemically interactive ensembles gives them inherent benefits in a variety of barrier and structural applications over current stiff and strong linear polymer technologies. |
| FILED | Thursday, February 16, 2017 |
| APPL NO | 15/434391 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/00 (20130101) C08G 63/065 (20130101) C08G 63/78 (20130101) C08G 63/127 (20130101) C08G 63/133 (20130101) C08G 69/32 (20130101) C08G 73/18 (20130101) C08G 73/22 (20130101) C08G 73/028 (20130101) C08G 73/1067 (20130101) Original (OR) Class C08G 75/32 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590294 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Yu Teng Liang (Chicago, Illinois); Ethan B. Secor (Evanston, Illinois); Pradyumna L. Prabhumirashi (Chicago, Illinois); Kanan P. Puntambekar (Chicago, Illinois); Michael L. Geier (Chicago, Illinois); Bok Y. Ahn (Cambridge, Massachusetts); Jennifer A. Lewis (Cambridge, Massachusetts) |
| ABSTRACT | A rapid, scalable methodology for graphene dispersion and concentration with a polymer-organic solvent medium, as can be utilized without centrifugation, to enhance graphene concentration. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 15/905358 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/01 (20130101) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 5/0023 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/19 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/32 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/14 (20130101) C09D 11/36 (20130101) C09D 11/38 (20130101) Original (OR) Class C09D 11/52 (20130101) C09D 11/322 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0005 (20130101) H01L 51/0045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590350 | Reams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); GOVERNMENT OF THE UNITED STATES as represented by THE SECRETARY OF THE AIR FORCE (Wright-Patterson Air Force Base, Ohio) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); The Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson Air Force Base, Ohio) |
| INVENTOR(S) | Josiah T. Reams (Lancaster, California); Andrew Guenthner (Lancaster, California); Joseph Mabry (Lancaster, California); Kevin Lamison (Lancaster, California); Anish Tuteja (Ann Arbor, Michigan); Arun K. Kota (Fort Collins, Colorado); Gibum Kwon (Ann Arbor, Michigan) |
| ABSTRACT | In various aspects, methods and apparatuses for liquid-liquid extraction are provided. In certain aspects, an emulsion can be formed by combining a feed stream, an extractant, and a surfactant. The feed stream comprises a plurality of distinct components including a first component to be removed therefrom. The feed stream may be selected from a group consisting of: a hydrocarbon feed stream and an azeotrope. Then, a portion of the first component is extracted from the feed stream (or emulsion) by contact with a superoleophobic and hygroscopic membrane filter that facilitates passage of the first component and extractant through the superoleophobic and hygroscopic membrane filter. A purified product is collected having the portion of the first component removed. Such methods are particularly useful for refining fuels and oils and separating azeotropes and other miscible component systems. Energy-efficient, continuous single unit operation apparatuses for conducting such separation techniques are also provided. |
| FILED | Friday, January 12, 2018 |
| APPL NO | 15/870524 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Separation B01D 11/0415 (20130101) B01D 11/0492 (20130101) B01D 61/246 (20130101) B01D 69/02 (20130101) B01D 69/10 (20130101) B01D 69/12 (20130101) B01D 2325/36 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/40 (20130101) C02F 1/44 (20130101) C02F 2101/32 (20130101) C02F 2101/325 (20130101) Acyclic or Carbocyclic Compounds C07C 29/86 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 21/00 (20130101) C10G 31/09 (20130101) Original (OR) Class C10G 33/06 (20130101) C10G 2300/202 (20130101) C10G 2400/02 (20130101) C10G 2400/04 (20130101) C10G 2400/08 (20130101) C10G 2400/28 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) C10L 1/026 (20130101) C10L 2200/0476 (20130101) C10L 2270/04 (20130101) C10L 2270/026 (20130101) C10L 2290/544 (20130101) C10L 2290/547 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249953 (20150401) Y10T 428/249978 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590456 | Jewett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Do Soon Kim (Evanston, Illinois); Erik D. Carlson (Chicago, Illinois); Alexander S. Mankin (River Forest, Illinois); Cedric Orelle (Chicago, Illinois); Teresa Szal (Forest Park, Illinois); Anne E. d'Aquino (Evanston, Illinois) |
| ABSTRACT | An engineered ribosome that includes a tethered subunit arrangement is disclosed, in which the engineered ribosome supports translation of a sequence defined polymer. Methods for making and using the engineered ribosome are also disclosed, including a method for preparing a sequence defined polymer using the engineered ribosome and a method for preparing a sequence defined polymer using the engineered ribosome in a two-protein translation system. The engineered ribosomes may be utilized in methods for incorporating unnatural amino acids into a sequence defined polymer. Also disclosed are optimized polynucleotide sequences for use as tethers and Shine-Dalgarno/anti-Shine-Dalgarno sequences. |
| FILED | Tuesday, November 29, 2016 |
| APPL NO | 15/363828 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590671 | Jee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Melvin W. Jee (Whitinsville, Massachusetts); Conor R. Hennessy (Brighton, Massachusetts) |
| ABSTRACT | A modular shelter system includes a floor panel having a first curved surface along a lateral edge on a top side of the floor panel and a first inside surface located inside of the first curved surface. The modular shelter system additionally includes a wall panel having a second curved surface along a bottom end of the wall panel, wherein the second curved surface is configured to rotate relative to the first curved surface, and wherein the second curved surface is configured to mate with the first curved surface. The wall panel further has a second inside surface located inside of the second curved surface, wherein the second inside surface is configured to mate with the first inside surface when the wall panel is erected over the floor panel. |
| FILED | Tuesday, September 26, 2017 |
| APPL NO | 15/715218 |
| ART UNIT | 3638 — Static Structures, Supports and Furniture |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/34321 (20130101) E04B 2001/34389 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 1/1205 (20130101) E04H 9/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590795 | Pratt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | William S. Pratt (West Hartford, Connecticut); Anand Nagaraj (Teaneck, New Jersey); Diane C. Kjelby (Middletown, Connecticut) |
| ABSTRACT | A vane arm may comprise a first end having a first surface and a second surface opposite the first surface. A vane stem aperture may be formed through the first end of the vane arm. The first surface may define a first perimeter of the vane stem aperture. The second surface may defines a second perimeter of the vane stem aperture. The second perimeter may comprise a circular or elliptical shape. A first wedge face and second wedge face may define a portion of the vane stem aperture. |
| FILED | Tuesday, October 17, 2017 |
| APPL NO | 15/786367 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 17/162 (20130101) Original (OR) Class F01D 17/165 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/20 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/60 (20130101) F05D 2240/12 (20130101) F05D 2260/79 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590798 | Luczak |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Blake Luczak (Pittsburgh, Pennsylvania) |
| ABSTRACT | A rotor includes a rotor hub, a plurality of blades mounted in a circumferentially-spaced arrangement on the rotor hub and a plurality of platform segments circumferentially arranged, respectively, between neighboring ones of the blades. The platform segments include core gas-path defining surfaces and are mounted with a freedom to circumferentially move relative to the neighboring ones of the blades. |
| FILED | Wednesday, March 19, 2014 |
| APPL NO | 14/771580 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/26 (20130101) F01D 5/3015 (20130101) F01D 5/3084 (20130101) F01D 11/008 (20130101) F01D 25/06 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/96 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591094 | Grimes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Keith R. Grimes (Hatboro, Pennsylvania); Nuri N. Bracey (Philadelphia, Pennsylvania) |
| ABSTRACT | A two-piece replaceable union nut for repairs on shipboard high pressure air systems. The replacement union nut is employed when an existing union nut has failed (i.e. cracked or broken) or has been identified as sub-standard due to material type or some other shortcoming, but the piping, tailpiece and thread piece are still in satisfactory condition. The two pieces fit around the pipe and mate using machined notches to form a complete union nut that is constrained in all directions and dimensionally equivalent to a standard union nut. The two-piece union nut facilitates replacement of a union nut in service without the need for cutting piping and reattaching the accompanying tailpiece, and testing the system as conventionally required. |
| FILED | Wednesday, June 08, 2016 |
| APPL NO | 15/176820 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 19/02 (20130101) Original (OR) Class F16L 55/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591235 | Michlin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Alex Michlin (Whiteford, Maryland) |
| ABSTRACT | A system for reducing an extraction force required for removing a spent munition cartridge case from a weapon after firing, the system including a chamber; and a plurality of movable components in the chamber that are configured to radially expand with a corresponding expansion of a fired munition cartridge case, wherein radial expansion of the plurality of movable components causes a rearward force on the plurality of movable components and the spent munition cartridge case. The chamber may include a tapered wall, and the plurality of movable components may matingly align with the tapered wall. The plurality of movable components may align with one another. Each movable component may include a tapered outer surface comprising an angle greater than an angle of an outer surface of a pre-fired cartridge case. |
| FILED | Tuesday, March 07, 2017 |
| APPL NO | 15/451542 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 15/14 (20130101) Original (OR) Class F41A 21/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591254 | Kenney |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Arthur Kenney (Spotsylvania, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | William Arthur Kenney (Spotsylvania, Virginia) |
| ABSTRACT | A computer-implemented method is provided for implementing wind correction for a projectile launching gun aiming at a target on a gun fire control system on an aircraft. The fire control method includes obtaining first physical parameters; executing a ballistics model to obtain a flight path of the projectile; obtaining number of points for wind direction and velocity across altitudes; executing a tracker model to obtain tracker location and initial gun state; obtaining closure tolerance and cross-correlation factor; modeling wind prediction to obtain a predicted wind column; incorporating the predicted wind column for wind column prediction for a projectile effect; and applying the projectile effect to the fire-control processor to adjust aiming the gun. The first physical parameters include wind column, gun state, ammunition type and aircraft flight conditions. The ballistics model obtains a flight path of the projectile based on the first physical parameters. The tracker model is based on the number of points and the flight path. The wind prediction is based on the closure tolerance, the cross-correlation factor, the tracker location and the initial gun state. The wind direction and velocity are obtained from multiple measurements or alternatively from a single-point measurement. |
| FILED | Thursday, January 03, 2019 |
| APPL NO | 16/239105 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Weapon Sights; Aiming F41G 3/08 (20130101) Original (OR) Class F41G 3/10 (20130101) F41G 3/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591264 | Gupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | Washington State University (Pullman, Washington) |
| INVENTOR(S) | Yogendra M Gupta (Spokane, Washington); Atakan Peker (Spokane, Washington) |
| ABSTRACT | A process for producing a munitions structure includes combining two or more transition metals including one or more of Zr, Hf, Ti, Ta, or Nb, and one or more other elements as alloying additions. The process further includes heating and fusing together the two or more transition metals and the one or more alloying additions to form a homogenous molten alloy. The homogenous molten alloy is cooled in a metallic mold to form a solid object with a desired shape for the munitions structure. |
| FILED | Wednesday, March 13, 2019 |
| APPL NO | 16/352488 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 1/02 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/74 (20130101) F42B 12/207 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591267 | Sorensen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Brett R. Sorensen (Bel Air, Maryland); Christopher S. Meyer (North East, Maryland); Richard L. Summers (Conowingo, Maryland); Jason C. Angel (Bel Air, Maryland); Timothy G. Farrand (Forest Hill, Maryland); Daniel R. Scheffler (Belcamp, Maryland) |
| ABSTRACT | A cannon projectile having an elongated body with a plurality of elongated and circumferentially spaced segments. At least one tether is attached to at least one end of the segments to hold the segments together. A deployment device, when activated, enables the segments to deploy radially outwardly into a pattern controlled at least in part by the at least one tether using aerodynamic and inertial forces only. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 15/720028 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/34 (20130101) F42B 12/60 (20130101) Original (OR) Class F42B 12/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591390 | Glaros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Edgewood Chemical Biological Center (APG, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Trevor G. Glaros (North East, Maryland); John M Nilles (Elkridge, Maryland); Jennifer W Sekowski (Forest Hill, Maryland); Harold S Wylie (North East, Maryland); Elizabeth S. Dhummakupt (Abingdon, Maryland); Phillip M Mach (Edgewood, Maryland) |
| ABSTRACT | An apparatus and method to capture aerosols and vapors on substrates from a large variety of sources and matrices for analysis using paper spray mass spectrometry (PS-MS) is disclosed. A holder for a PS cartridge has better direct sampling efficiency, direct capture on substrate, and lower limits of detection thereby improving the collection and analysis of aerosols and vapors. An apparatus and method for aerosol and vapor collection, from both anthropogenic and environmental sources, for example, that is compact and compatible with hand held devices and unmanned vehicles is also disclosed. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 15/813326 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2273 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) H01J 49/0409 (20130101) H01J 49/0422 (20130101) H01J 49/0427 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591423 | Tam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kent K. Tam (Rowland Heights, California); Leon Burks, Jr. (Los Angeles, California); Mark D. Brown (San Pedro, California) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Kent K. Tam (Rowland Heights, California); Leon Burks, Jr. (Los Angeles, California); Mark D. Brown (San Pedro, California) |
| ABSTRACT | A non-destructive, inline, multi-channel fabric conductivity measurement system uses an array of opposing paired transmit/receive microwave horns on opposite sides of a fabric material moving in a production line, each horn pair corresponding to a channel in the system. A processor-based controller can control channel hopping, frequency hopping, and measurement orientation to acquire measurements of material conductivity and anisotropy, which measurements can be analyzed for defects that can be flagged in real time during production. Measurements and/or analyses can be stored to make roll-to-roll, batch-to-batch, day-to-day, or production-phase-to-production-phase comparisons useful in identifying the sources of production problems and/or the causes of corrections. |
| FILED | Wednesday, March 22, 2017 |
| APPL NO | 15/466558 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/02 (20130101) Original (OR) Class G01N 33/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591458 | Parker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Kevin Kit Parker (Cambridge, Massachusetts); Johan Ulrik Lind (Boston, Massachusetts); Jennifer Ann Lewis (Cambridge, Massachusetts); Joost Johan Vlassak (Lexington, Massachusetts); Hongyan Yuan (Cangzhou, China PRC); Travis Alexander Busbee (Somerville, Massachusetts); Ian Perkins (Bridgewater, Massachusetts); Christophe Chantre (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments described herein are directed to devices for supporting growth of anisotropic muscle tissue layers and in vitro readout and quantification of force generated by the tissue layers using one or more strain-sensing elements integrated into the device. Embodiments also include multiplexed apparatuses of multiple independent devices, methods of fabricating the devices and apparatuses, and methods of using the devices and apparatuses. |
| FILED | Wednesday, February 18, 2015 |
| APPL NO | 15/116258 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/053 (20130101) A61B 5/4519 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591632 | Howell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
| ASSIGNEE(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
| INVENTOR(S) | John C. Howell (Jerusalem, Israel); Christopher Mullarkey (Beacon, New York); Julian Martinez-Rincon (Redwood City, California) |
| ABSTRACT | Embodiments of the present invention may be generally related to methods, devices, and systems which measure a gravitational field. The methods and devices may utilize an interferometer to measure tilt of a pendulum, where the tilt of the pendulum is due to a gravitational force associated with a target object. In some embodiments, the interferometer may be a displaced, even parity, Sagnac interferometer. Additionally, the interferometer may be operated in the inverse weak value domain. In some embodiments, the pendulum and interferometric readout may measure relative gravitational fields that are transverse to Earth's gravitational field. In at least some embodiments, methods and devices may have shot noise limited sensitivity sufficient to detect one kilogram 25 meters away and may have a 1 nGal resolution after mere seconds of integration. Embodiments disclosed may be used to gravitationally map density fluctuations in a target object, including the human body. |
| FILED | Friday, September 16, 2016 |
| APPL NO | 15/759673 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 1/00 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 7/04 (20130101) G01V 7/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591650 | Shvets et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IP Equity Management, LLC (Nashville, Tennessee) |
| ASSIGNEE(S) | IP EQUITY MANAGEMENT, LLC (Austin, Texas) |
| INVENTOR(S) | Gennady Shvets (Austin, Texas); Chih-Hui Wu (Austin, Texas) |
| ABSTRACT | A solar thermophotovoltaic system includes a heat exchange pipe containing a heat exchange fluid, and a thin-film integrated spectrally-selective plasmonic absorber emitter (ISSAE) in direct contact with an outer surface of the heat exchange pipe, the ISSAE including an ultra-thin non-shiny metal layer comprising a metal strongly absorbing in a solar spectral range and strongly reflective in an infrared spectral range, the metal layer having an inner surface in direct contact with an outer surface of the heat exchange pipe. The system further includes a photovoltaic cell support structure having an inner surface in a concentric configuration surrounding at least a portion of the ISSAE; and an airgap separating the support structure and the outer surface of the metal layer. The support structure includes a plurality of photovoltaic cells arranged on a portion of the inner surface of the support structure and configured to receive emissions from the ISSAE, and a solar energy collector/concentrator configured to allow solar radiation to impinge a portion of the metal layer. |
| FILED | Wednesday, January 16, 2019 |
| APPL NO | 16/249295 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 60/00 (20180501) F24S 70/20 (20180501) Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) Original (OR) Class Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591689 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oracle International Corporation (Redwood Shores, California) |
| ASSIGNEE(S) | Oracle International Corporation (Redwood Shores, California) |
| INVENTOR(S) | Chaoqi Zhang (Atlanta, Georgia); Hiren D. Thacker (San Diego, California); Ivan Shubin (San Diego, California); Xuezhe Zheng (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California) |
| ABSTRACT | The disclosed embodiments provide an apparatus for connecting one or more optical fibers to an optoelectronic system. This apparatus includes a packaged optoelectronic module (POeM) comprising an optical connector, a silicon photonic (SiP) chip, an integrated circuit (IC) chip, at least one laser chip and a package substrate. The apparatus also includes an assembly adapter enclosing the POeM, wherein the assembly adapter includes a mechanical transfer (MT) ferrule cavity, which includes one or more coarse-alignment structures to guide an MT ferrule enclosing at least one optical fiber during assembly of the apparatus. The assembly adapter is comprised of a solder-reflow-compatible material to facilitate bonding the assembly adapter to a circuit board. |
| FILED | Monday, February 06, 2017 |
| APPL NO | 15/425887 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/423 (20130101) G02B 6/3825 (20130101) G02B 6/3849 (20130101) G02B 6/3897 (20130101) G02B 6/4238 (20130101) G02B 6/4251 (20130101) G02B 6/4257 (20130101) G02B 6/4261 (20130101) Original (OR) Class G02B 6/4269 (20130101) G02B 6/4292 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591871 | Pellizzari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico) |
| ASSIGNEE(S) | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED, BY THE SECRETARY OF THE AIR FORCE. (Washington, District of Columbia) |
| INVENTOR(S) | Casey J. Pellizzari (Prattville, Alabama); Mark F. Spencer (Albuquerque, New Mexico); Charles A. Bouman, Jr. (West Lafayette, Indiana) |
| ABSTRACT | Light reflected from an illuminated object is mixed with a reference beam and sensed at a sensor array of a digital hologram apparatus. Digital hologram data, determined from the sensed light, is dependent upon complex valued reflection coefficients of the object and upon phase perturbations in propagation paths between the object and the sensor array. Reflectance values, which may be dependent upon expected values of the absolute square of the reflection coefficients, and phase perturbations are determined for which a test function is at an extremum, where the test function contains a data fidelity term dependent upon the hologram data from a single hologram, a first regularization term dependent upon the phase perturbations and a second regularization term dependent upon the reflectance values. An image of the object may be formed from the reflectance values and a wavefront of the reflected light may be determined from the phase perturbations. |
| FILED | Monday, September 09, 2019 |
| APPL NO | 16/565335 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/32 (20130101) G03H 1/0443 (20130101) Original (OR) Class G03H 1/0866 (20130101) G03H 1/2202 (20130101) G03H 2001/0452 (20130101) G03H 2001/2247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591950 | McDonald et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian McDonald (Taft, Tennessee); Jeremy Rice (Huntsville, Alabama); John Stewart (Redstone Arsenal, Alabama) |
| ABSTRACT | The application relates to a Ramjet solid fuel having an ignition temperature of less than 400° C., the fuel comprising a bis-(ethylene oxy) methane polysulfide polymer (BMPP) and hydroxyl-terminated polybutadiene (HTPB), the copolymer having a BMPP/HTPB weight ratio of from 1/3 to 3/1; and the fuel comprising at least 85 weight % copolymer. The BMPP comprises from 5 to 8 weight percent mercaptan. Furthermore, the BMPP is selected from HS(RSS)aCH2CH((SSR)cCSH)CH2(SSR)bSH a) where R═—(CH2)2OCH2O(CH2)2— and a+b+c<7; and H(SC2H4OCH2OC2H4S)nH where n=7. b) |
| FILED | Wednesday, April 19, 2017 |
| APPL NO | 15/491433 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 5/00 (20130101) C10L 5/406 (20130101) C10L 2200/0259 (20130101) C10L 2200/0263 (20130101) C10L 2250/04 (20130101) C10L 2270/04 (20130101) Jet-propulsion Plants F02K 7/105 (20130101) F02K 9/95 (20130101) Digital Fluid-pressure Computing Devices G06D 5/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592310 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Peter Chao-yuan Li (McLean, Virginia); Jeffrey R. Collmann (Washington, District of Columbia); Jane W. Blake (Alexandria, Virginia); Mark G. Polyak (Alexandria, Virginia); James M. Wilson (Alexandria, Virginia); Jae In Yoon (Centreville, Virginia); Manabu Torii (Falls Church, Virginia); Carla S. Thomas (Bodega Bay, California) |
| ABSTRACT | A system and method involves detecting operational social disruptive events on a global scale, modeling data in conjunction with linguistics analysis to establish responsive actions, and generating visualization and executing models for communicating information. |
| FILED | Wednesday, April 18, 2018 |
| APPL NO | 15/955823 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) Original (OR) Class G06F 16/9535 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592433 | Whelihan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David Whelihan (Framingham, Massachusetts) |
| ABSTRACT | A method for processing addressable encrypted data representing addressable cleartext data uses an integrated circuit including a processor circuit. The method includes processing the addressable cleartext data in the processor circuit without storing said cleartext data outside the processor circuit. |
| FILED | Monday, December 14, 2015 |
| APPL NO | 14/967922 |
| ART UNIT | 2498 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0802 (20130101) G06F 12/1408 (20130101) Original (OR) Class G06F 21/71 (20130101) G06F 2212/60 (20130101) G06F 2212/402 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592667 | Long et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INVINCEA, INC. (Fairfax, Virginia) |
| ASSIGNEE(S) | Invincea, Inc. (Reston, Virginia) |
| INVENTOR(S) | Alexander Mason Long (Sterling, Virginia); Joshua Daniel Saxe (Washington, District of Columbia) |
| ABSTRACT | An apparatus can include a processor that can extract, from an input binary file, an image data structure, and can scale the image data structure to a predetermined size, and/or modify the image data structure to represent a grayscale image. The processor can calculate a modified pixel value for each pixel in the image data structure, and can define a binary vector based on the modified pixel value for each pixel in the image data structure. The processor can also identify a set of nearest neighbor binary vectors for the binary vector based on a comparison between the binary vector and a set of reference binary vectors stored in a malware detection database. The processor can then determine a malware status of the input binary file based on the set of nearest neighbor binary vectors satisfying a similarity criterion associated with a known malware image from a known malware file. |
| FILED | Monday, December 18, 2017 |
| APPL NO | 15/845231 |
| ART UNIT | 2493 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/565 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592687 | Kapadia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); United States of America as Represented by The Secretary of The Navy (Arlington, Virginia) |
| INVENTOR(S) | Apu Kapadia (Bloomington, Indiana); Robert E. Templeman (Bloomington, Indiana); David Crandall (Bloomington, Indiana); Mohammed Korayem (Bloomington, Indiana) |
| ABSTRACT | A method and device for classifying collected images. The method and device include instructions to compare a captured image to a known set of images to determine the location depicted therein; and applying a classification upon the image based upon the determined location depicted therein and whether the determined location indicates that the image has the potential to depict privacy sensitive information. |
| FILED | Thursday, October 09, 2014 |
| APPL NO | 15/029559 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/51 (20190101) G06F 16/5838 (20190101) G06F 16/5854 (20190101) G06F 16/5862 (20190101) G06F 16/5866 (20190101) G06F 21/6245 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/78 (20130101) G06K 9/00664 (20130101) G06K 9/00771 (20130101) G06K 9/4671 (20130101) G06K 9/6202 (20130101) G06K 9/6267 (20130101) G06K 9/6297 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593778 | Basaran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cemalettin Basaran (Medina, New York); Weixiang Zhang (Buffalo, New York); Tarek Ragab (Jonesboro, Arkansas) |
| ASSIGNEE(S) | Cemalettin Basaran (Medina, New York) |
| INVENTOR(S) | Cemalettin Basaran (Medina, New York); Weixiang Zhang (Buffalo, New York); Tarek Ragab (Jonesboro, Arkansas) |
| ABSTRACT | The present invention disclose an Electrostatic doping (ED)-based graphene nanoribbon (GNR) tunneling field-effect transistor (TFET) with tri-gate design. This device uses hydrogen-passivated GNR heterojunction as a carrier path way and functions as a power switch providing a switching speed of ˜0.3 ps−1 an ION/IOFF ratio as high as 1014 with the on-state current in the order of 103 μA/μm. This disclosed invention consists of two electrode, two electrode extensions, six metallic gate regions, and six dielectric regions. |
| FILED | Wednesday, May 15, 2019 |
| APPL NO | 16/413049 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/66015 (20130101) Original (OR) Class H01L 29/66219 (20130101) H01L 29/66977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593824 | Yoon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Woojun Yoon (Fairfax, Virginia); David Scheiman (Alexandria, Virginia); Phillip Jenkins (Cleveland Heights, Ohio); Robert J. Walters (Alexandria, Virginia) |
| ABSTRACT | A method for making an ultra-thin, flexible crystalline silicon solar cell from thick, inflexible cells. A thick, inflexible cell having a plurality of electrical contacts on the back side thereof is adhered to a mount by means of a temporary bonding adhesive tape and a thickness of the mounted stack. A thickness of the bonding tape and the back-side contacts is determined and compared to a desired thickness of the final cell. Excess material is ground from the front side of the stack to obtain a thinned stack having the desired thickness and the thinned stack is removed from the mount to produce an ultra-thin, flexible rear-contact Si solar cell having a total thickness of less than 80 μm and a bending radius of less than 20 mm. The front surface can be textured, with a passivation layer and/or a dielectric layer being deposited thereon. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/264845 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/1804 (20130101) H01L 31/1868 (20130101) Original (OR) Class H01L 31/1892 (20130101) H01L 31/02363 (20130101) H01L 31/022441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593830 | Liao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Yitao Liao (Redwood City, California); Theodore D. Moustakas (Dover, Massachusetts) |
| ABSTRACT | Semiconductor structures involving multiple quantum wells provide increased efficiency of UV and visible light emitting diodes (LEDs) and other emitter devices, particularly at high driving current. LEDs made with the new designs have reduced efficiency droop under high current injection and increased overall external quantum efficiency. The active region of the devices includes separation layers configured between the well layers, the one or more separation regions being configured to have a first mode to act as one or more barrier regions separating a plurality of carriers in a quantum confined mode in each of the quantum wells being provided on each side of the one or more separation layers and a second mode to cause spreading of the plurality of carriers across each of the quantum wells to increase an overlap integral of all of the plurality of carriers. The devices and methods of the invention provide improved efficiency for solid state lighting, including high efficiency ultraviolet LEDs. |
| FILED | Saturday, September 30, 2017 |
| APPL NO | 15/721786 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Electric Digital Data Processing G06F 17/50 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/04 (20130101) H01L 33/06 (20130101) Original (OR) Class H01L 33/0025 (20130101) H01L 33/32 (20130101) H01L 33/0062 (20130101) H01L 33/145 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/343 (20130101) H01S 5/34333 (20130101) H01S 5/34346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593871 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| INVENTOR(S) | Judy Z. Wu (Lawrence, Kansas); Jamie Wilt (Olathe, Kansas); Ryan Goul (Topeka, Kansas); Jagaran Acharya (Lawrence, Kansas) |
| ABSTRACT | Methods for forming tunnel barrier layers are provided, including a method comprising exposing a surface of a material, the surface free of oxygen, to an initial water pulse for a pulse time and at a pulse temperature, the pulse time and pulse temperature selected to maximize hydroxylation of the surface; and exposing the hydroxylated surface to alternating, separated pulses of precursors under conditions to induce reactions between the hydroxylated surface and the precursors to form a tunnel barrier layer on the surface of the material via atomic layer deposition (ALD), the tunnel barrier layer having an average thickness of no more than 1 nm and being formed without an intervening interfacial layer between the tunnel barrier layer and the surface of the material. |
| FILED | Tuesday, May 22, 2018 |
| APPL NO | 15/985979 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/223 (20130101) H01L 39/2493 (20130101) H01L 43/08 (20130101) H01L 43/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594010 | McKay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ian Salmon McKay (Seattle, Washington); Ruaridh R. Macdonald (London, United Kingdom); Thomas B. Milnes (Beverly, Massachusetts) |
| ABSTRACT | An anaerobic aluminum-water electrochemical cell includes electrode stacks, each electrode stack having an aluminum or aluminum alloy anode, and at least one solid cathode configured to be electrically coupled to the anode. The cell further includes a liquid electrolyte between the anode and the at least one cathode, one or more physical separators between each electrode stack adjacent to the cathode, a housing configured to hold the electrode stacks, the electrolyte, and the physical separators, and a water injection port, in the housing, configured to introduce water into the housing. |
| FILED | Wednesday, December 04, 2013 |
| APPL NO | 14/096810 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/463 (20130101) H01M 6/32 (20130101) H01M 6/34 (20130101) H01M 12/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594030 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Yongjae Lee (Latham, New York); Joseph Alfred Iannotti (Glenville, New York); Steven YueHin Go (Schenectady, New York) |
| ABSTRACT | A true time delay (TTD) module includes a substrate and a transmission line formed on the substrate. The transmission line includes time delay lines that define signal paths of varying lengths between a signal input and a signal output of the TTD module. A plurality of switching elements are positioned along the transmission line and are selectively controllable to define a signal transmission path between the signal input and the signal output. The switching elements include an input switching element positioned at a first end of each of the plurality of time delay lines, an output switching element positioned at a second end of each of the plurality of time delay lines, and at least one intermediate switching element positioned between the input switching element and the output switching element of at least one of the plurality of time delay lines. |
| FILED | Wednesday, February 01, 2017 |
| APPL NO | 15/421915 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/184 (20130101) H01P 9/00 (20130101) Antennas, i.e Radio Aerials H01Q 3/30 (20130101) H01Q 3/2682 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594261 | Dutta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Moumita Dutta (San Antonio, Texas); Ruyan Guo (San Antonio, Texas); Amar Bhalla (San Antonio, Texas); Soutik Betal (San Antonio, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas Systems (Austin, Texas) |
| INVENTOR(S) | Moumita Dutta (San Antonio, Texas); Ruyan Guo (San Antonio, Texas); Amar Bhalla (San Antonio, Texas); Soutik Betal (San Antonio, Texas) |
| ABSTRACT | Disclosed are various embodiments of a terahertz wave modulator. The wave modulator can include one or more layers of piezoelectric/ferroelectric single crystal or polycrystalline material. The crystalline material can be configured to resonate when a low-energy external excitation is applied. An incident terahertz waveform can be dynamically controlled when the incident terahertz waveform interacts with the at least one layer of piezoelectric crystalline material while the at least one layer of piezoelectric crystalline material is resonating. The dynamic control of the incident terahertz waveform can be with respect to at least one of a phase shift and an amplitude modulation of the waveform. |
| FILED | Tuesday, July 18, 2017 |
| APPL NO | 15/652656 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/083 (20130101) Modulation H03C 1/02 (20130101) H03C 1/46 (20130101) H03C 3/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594268 | Smith, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cree, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Thomas J. Smith, Jr. (Raeigh, North Carolina) |
| ABSTRACT | Monolithic microwave integrated circuits are provided that include a substrate, a transmit/receive selection device that is formed on the substrate, a high power amplifier formed on the substrate and coupled to a first RF port of the transmit/receive selection device, a low noise amplifier formed on the substrate and coupled to a second RF port of the transmit/receive selection device and a protection circuit that is coupled to a first control port of the transmit/receive selection device. |
| FILED | Friday, May 18, 2018 |
| APPL NO | 15/983527 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/78 (20130101) H01L 29/2003 (20130101) Amplifiers H03F 1/26 (20130101) Original (OR) Class H03F 3/193 (20130101) H03F 3/195 (20130101) H03F 3/213 (20130101) H03F 2200/294 (20130101) Transmission H04B 7/0868 (20130101) H04B 17/13 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594299 | Veeder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Senseeker Engineering Inc. (Goleta, California) |
| ASSIGNEE(S) | SENSEEKER ENGINEERING, INC. (Santa Barbara, California) |
| INVENTOR(S) | Kenton Veeder (Santa Barbara, California); Aaron Bluestone (Goleta, California); Christoph von Jutrzenka Trzebiatowski (Goleta, California); Nishant Dhawan (Santa Barbara, California) |
| ABSTRACT | The present disclosure provides an analog counter circuit for use in a minimal-sized circuitry. The analog counter circuit of the present disclosure can provide much higher resolution versus power consumption and layout area as compared to conventional digital counters. The analog counter circuit of the present disclosure can also provide much better bias supply management, step accuracy, multi-element step uniformity and lower supply spiking as compared to conventional analog counter architectures. The compact size of the disclosed counter circuit allows better integration of arrayed elements, such as, an array of image sensing pixels or an array of artificial neurons. |
| FILED | Thursday, April 12, 2018 |
| APPL NO | 15/951196 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 11/265 (20130101) Original (OR) Class Pulse Technique H03K 25/00 (20130101) Pictorial Communication, e.g Television H04N 5/378 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594319 | Friedman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanson, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Joseph S. Friedman (Rochester, New York); Michael L. Geier (Chicago, Illinois); Mark C. Hersam (Wilmette, Illinois); Alan V. Sahakian (Northbrook, Illinois) |
| ABSTRACT | A logic gate and a cascaded logic family is described that uses the unique ambipolar behavior, e.g., of carbon nanotubes. A complementary VT-drop ambipolar carbon nanotube logic can provide a decrease in device count compared to previous ambipolar carbon nanotube field effect transistor logic structures, enabling power and/or speed improvements. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/591833 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 7/501 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0048 (20130101) H01L 51/0554 (20130101) Pulse Technique H03K 19/082 (20130101) Original (OR) Class H03K 19/212 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594400 | Chung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Functional Fabrics of America, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Advanced Functional Fabrics of America, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Chia-Chun Chung (Malden, Massachusetts); Jason Cox (Ashland, Massachusetts); Yoel Fink (Brookline, Massachusetts); Mihai Ibanescu (Somerville, Massachusetts); Chhea Chhav (Dracut, Massachusetts) |
| ABSTRACT | A textile capable of detecting electromagnetic radiation includes interlaced fibers; a photodetector embedded, as a result of a fiber draw process, within a particular one of the fibers; and a first electrical conductor extending within the particular fiber and along a longitudinal axis thereof. The first electrical conductor is in electrical contact with the photodetector, and the photodetector position in the particular fiber corresponds to a lowest energy configuration relative to a pattern of flow along the longitudinal axis of the particular fiber throughout the fiber draw process. A method of manufacturing the textile and a system including the textile are also disclosed. |
| FILED | Tuesday, June 12, 2018 |
| APPL NO | 16/006343 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0017 (20130101) A61B 5/6802 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00721 (20130101) Transmission H04B 10/11 (20130101) H04B 10/112 (20130101) H04B 10/803 (20130101) H04B 10/2581 (20130101) Original (OR) Class H04B 10/2587 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594409 | Primerano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Richard Anthony Primerano (Philadelphia, Pennsylvania); Moshe Kam (Philadelphia, Pennsylvania); Kapil R. Dandekar (Philadelphia, Pennsylvania); Cole Gindhart (Philadelphia, Pennsylvania) |
| ABSTRACT | Ultrasonic through metal communication systems are an effective solution for transmitting data across a metal barrier when the structural integrity of the barrier cannot be compromised by physically penetrating it. Substantial improvements in through metal communication systems have been made in recent years, enabling high speed communications of up to 15 Mbps, as well as power transmission up to 30 W across flat walls. A system is described that allows for ultrasonic through metal communication across the wall of a steel tube. Primary challenges of 1) transducer contact, 2) curvature effect on echoes, and 3) alignment are analyzed and addressed through the use of radial mode piezoelectric transducers, transducer “horns”, and Electromagnetic Acoustic Transducers (EMATs). The resulting system shows no significant loss due to changes in alignment, allows for the use of either piezoelectric transducers or EMATs externally, and achieves max data rates of approximately 600 kbps without echo equalization. |
| FILED | Friday, December 02, 2016 |
| APPL NO | 15/368015 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Transmission H04B 11/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594705 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shouhuai Xu (Helotes, Texas); Moustafa Elsayed Saleh (San Antonio, Texas); Edward Paul Ratazzi (Rome, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shouhuai Xu (Helotes, Texas); Moustafa Elsayed Saleh (San Antonio, Texas); Edward Paul Ratazzi (Rome, New York) |
| ABSTRACT | Disclosed herein are new methods and systems for detecting obfuscated programs. We build a recursive traversal disassembler that extracts the control flow graph of binary files. This allows us to detect the presence of interleaving instructions, which is typically an indication of the opaque predicate anti-disassembly trick. Our detection system uses some novel features based on referenced instructions and the extracted control flow graph that clearly distinguishes between obfuscated and normal files. When these are combined with a few features based on file structure, we achieve a very high detection rate of obfuscated files. |
| FILED | Thursday, October 06, 2016 |
| APPL NO | 15/287705 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) Original (OR) Class H04L 63/1425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594722 | Boggs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Nathaniel Gordon Boggs (New York, New York); Salvatore J. Stolfo (New York, New York) |
| ABSTRACT | Methods, systems and media for evaluating layered computer security products are provided. In some embodiments, the method comprises: (a) identifying portions of attack data associated with an attack; (b) linking the portions of attack data; (c) testing security products using the linked attack data, at least two of the security products using different portions of the linked attack data; (d) storing the results of the testing; (e) repeating (a)-(d) for multiple attacks; receiving information identifying a subset of the security products from a remote computing device; identifying a first set of detected attacks for each of the plurality of security product using the stored results; determining a number of attacks in a union of each of the first sets of identified attacks; determining a detection rate for the identified security products based on the union and the number of tested attacks; and causing the detection rate to be presented. |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/047427 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/08 (20130101) H04L 43/028 (20130101) H04L 63/1416 (20130101) H04L 63/1425 (20130101) H04L 63/1433 (20130101) Original (OR) Class H04L 63/1491 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594976 | Lentz |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua Lentz (Niceville, Florida) |
| ABSTRACT | Systems and methods for wide field of view (FOV) image projection using a spatial light modulator (SLM) and a fast steering mirror (FSM) cooperatively managed by a projection sequence controller. The computer-implemented process determines projection regions within the FOV, creates sub-images of an input target image for each of the regions, and operates the SLM and FSM to time-division multiplex sequential projections of each of the sub-images and to direct each projection to a respective region in the FOV within an observer frame rate. The projection sequence controller determines the number projection regions within the FOV based on a projection frame time of the SLM (including a frame read-in time and a modulation time), a mirror steering time of the FSM, and the observer frame rate. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/257703 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 26/0816 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 21/2066 (20130101) Pictorial Communication, e.g Television H04N 5/7441 (20130101) H04N 5/7458 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10589214 | Widger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky) |
| INVENTOR(S) | Leland R. Widger (Lexington, Kentucky); Guojie Qi (Lexington, Kentucky); Kun Liu (Lexington, Kentucky); Jonathan Bryant (Lexington, Kentucky); Cameron A. Lippert (Lexington, Kentucky); Kunlei Liu (Lexington, Kentucky) |
| ABSTRACT | The present invention relates to methods for improving carbon capture by providing particles within an amine solvent. The particles provide for increased turbulence at the interface between the counter-flowing gas and solvent, which allows for increased amine and carbamate salt diffusion between the liquid film and bulk. |
| FILED | Thursday, February 02, 2017 |
| APPL NO | 15/423042 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/62 (20130101) B01D 53/78 (20130101) B01D 53/1425 (20130101) B01D 53/1475 (20130101) Original (OR) Class B01D 53/1493 (20130101) B01D 2252/60 (20130101) B01D 2252/202 (20130101) B01D 2252/2041 (20130101) B01D 2252/20405 (20130101) B01D 2252/20421 (20130101) B01D 2252/20431 (20130101) B01D 2252/20447 (20130101) B01D 2252/20484 (20130101) B01D 2252/20489 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589216 | Dutta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Prabir Kumar Dutta (Worthington, Ohio); Yanzuo Li (Columbus, Ohio); Bo Wang (Columbus, Ohio) |
| ABSTRACT | Membranes, methods of making the membranes, and methods of using the membranes are described herein. The membranes can comprise a gas permeable support and a continuous phase comprising a selective inorganic material disposed within the gas permeable support. In some embodiments, the membranes can exhibit a CO2:N2 selectivity of at least 10 at 24° C. The membranes can be bendable, such that when the membranes are wrapped around a 1.5-inch diameter cylinder and returned to a planar conformation, the CO2:N2 selectivity of the membranes is at least 25% of the CO2:N2 selectivity of the membranes prior to having been wrapped around the cylinder. |
| FILED | Friday, November 13, 2015 |
| APPL NO | 15/526908 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/228 (20130101) Original (OR) Class B01D 69/10 (20130101) B01D 71/028 (20130101) B01D 2053/221 (20130101) B01D 2256/22 (20130101) B01D 2257/404 (20130101) B01D 2257/504 (20130101) Non-metallic Elements; Compounds Thereof; C01B 39/04 (20130101) C01B 39/40 (20130101) C01B 39/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589225 | Olson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Midwest Energy Emissions Corp. (Corsicana, Texas) |
| ASSIGNEE(S) | Midwest Energy Emissions Corp. (Lewis Center, Ohio) |
| INVENTOR(S) | Edwin S. Olson (Grand Forks, North Dakota); Michael J. Holmes (Thompson, North Dakota); John Henry Pavlish (East Grand Forks, Minnesota) |
| ABSTRACT | A promoted activated carbon sorbent is described that is highly effective for the removal of mercury from flue gas streams. The sorbent comprises a new modified carbon form containing reactive forms of halogen and halides. Optional components may be added to increase reactivity and mercury capacity. These may be added directly with the sorbent, or to the flue gas to enhance sorbent performance and/or mercury capture. Mercury removal efficiencies obtained exceed conventional methods. The sorbent can be regenerated and reused. Sorbent treatment and preparation methods are also described. New methods for in-flight preparation, introduction, and control of the active sorbent into the mercury contaminated gas stream are described. |
| FILED | Thursday, May 14, 2015 |
| APPL NO | 14/712558 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/10 (20130101) B01D 53/64 (20130101) Original (OR) Class B01D 2253/102 (20130101) B01D 2257/602 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/02 (20130101) B01J 20/04 (20130101) B01J 20/10 (20130101) B01J 20/12 (20130101) B01J 20/20 (20130101) B01J 20/22 (20130101) B01J 20/027 (20130101) B01J 20/041 (20130101) B01J 20/043 (20130101) B01J 20/106 (20130101) B01J 20/223 (20130101) B01J 20/0262 (20130101) B01J 20/3416 (20130101) B01J 20/28004 (20130101) B01J 20/28016 (20130101) B01J 2220/42 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 95/901 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589228 | Hopkinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David P. Hopkinson (Morgantown, West Virginia); Nicholas Siefert (Pittsburgh, Pennsylvania); Robert L. Thompson (Pittsburgh, Pennsylvania); Megan Macala (Pittsburgh, Pennsylvania); Lei Hong (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | David P. Hopkinson (Morgantown, West Virginia); Nicholas Siefert (Pittsburgh, Pennsylvania); Robert L. Thompson (Pittsburgh, Pennsylvania); Megan Macala (Pittsburgh, Pennsylvania); Lei Hong (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present disclosure provides a method for the separation of a gas constituent from a gaseous mixture. The disclosure also provides polyethylene glycol disubstituted siloxane based solvents for use in the method. These solvents are of use for pre-combustion CO2 capture and are capable of replacing glycol-based solvents while offering operation at a higher temperature region. These solvents are also of use for generation of hydrogen from reformed natural gas or syngas, adjusting CO/H2 ratio for Coal & Biomass to Liquids, removal of CO2 from syngas for coal & biomass to NH3/Fertilizer, natural gas sweetening, and upgrading of landfill and biogas. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 15/989444 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/8618 (20130101) Original (OR) Class B01D 2252/2026 (20130101) B01D 2257/504 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589910 | Lavelock |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Rick L. Lavelock (Pleasant Hill, Missouri) |
| ABSTRACT | A container assembly with an expiration date alarm that preserves its battery life by only triggering its alarm when needed. The container assembly includes a container for enclosing a food item, medication, or other product that should not be used after an expiration date; a sensor for sensing when the container has been opened; an alarm; and a timing circuit coupled with the sensor and the alarm for triggering the alarm only if the container is opened after the expiration date has been reached. |
| FILED | Tuesday, December 08, 2015 |
| APPL NO | 14/963024 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 51/248 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590005 | Dandeneau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Christopher S. Dandeneau (Aiken, South Carolina); Jake W. Amoroso (Aiken, South Carolina) |
| ABSTRACT | One-step solution combustion synthesis (SCS) methods for fabricating durable crystalline transuranic-doped rare earth zirconium pyrochlores are described. Methods are fast, amenable to upscaling, and present a simple strategy for producing crystalline ceramic materials that meet the minimum attractiveness criteria for special nuclear material. The methods include analysis of reactants and reaction conditions to select proper fuel as well as proper fuel content so as to encourage formation of the crystalline product in a single-step synthesis procedure. |
| FILED | Tuesday, March 27, 2018 |
| APPL NO | 15/936615 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/20 (20130101) C01B 21/0422 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/0018 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 25/006 (20130101) C01G 56/003 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590294 | Hersam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Yu Teng Liang (Chicago, Illinois); Ethan B. Secor (Evanston, Illinois); Pradyumna L. Prabhumirashi (Chicago, Illinois); Kanan P. Puntambekar (Chicago, Illinois); Michael L. Geier (Chicago, Illinois); Bok Y. Ahn (Cambridge, Massachusetts); Jennifer A. Lewis (Cambridge, Massachusetts) |
| ABSTRACT | A rapid, scalable methodology for graphene dispersion and concentration with a polymer-organic solvent medium, as can be utilized without centrifugation, to enhance graphene concentration. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 15/905358 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/01 (20130101) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 5/0023 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/19 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/32 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/14 (20130101) C09D 11/36 (20130101) C09D 11/38 (20130101) Original (OR) Class C09D 11/52 (20130101) C09D 11/322 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0005 (20130101) H01L 51/0045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590359 | Felix |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois) |
| ASSIGNEE(S) | GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois) |
| INVENTOR(S) | Larry G. Felix (Pelham, Alabama) |
| ABSTRACT | A biomass-derived thermosetting polymer material being a product of processing a biomass feed material via a twin screw extruder having a length extending between an inlet and an outlet. Hot water from a water heater is injected into at least one inlet along the length of the twin screw extruder, the at least one inlet generally corresponding with a pressure boundary within the twin screw extruder. A pressure-sustaining valve is connected between the length of the twin screw extruder and the outlet, with the valve being adjusted to produce the biomass-derived thermosetting polymer material. |
| FILED | Wednesday, August 17, 2016 |
| APPL NO | 15/238981 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/022 (20190201) B29C 48/67 (20190201) B29C 48/92 (20190201) B29C 48/268 (20190201) B29C 48/402 (20190201) B29C 48/832 (20190201) B29C 48/834 (20190201) B29C 2948/92704 (20190201) Derivatives of Natural Macromolecular Compounds C08H 8/00 (20130101) Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 7/10 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 5/442 (20130101) C10L 9/086 (20130101) Original (OR) Class C10L 2200/0469 (20130101) C10L 2290/02 (20130101) C10L 2290/06 (20130101) C10L 2290/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) Y02E 50/30 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/145 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590398 | Negi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NMC, INC. (Los Alamos, New Mexico); LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | NMC, INC. (Los Alamos, New Mexico); LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Sangeeta Negi (Los Alamos, New Mexico); Richard Thomas Sayre (Los Alamos, New Mexico); Shawn Robert Starkenburg (Los Alamos, New Mexico) |
| ABSTRACT | Phototropin is a blue light receptor, which mediates a variety of blue-light elicited physiological processes in plants and algae. In higher plants these processes include phototropism, chloroplast movement and stomatal opening. In the green alga Chlamydomonas reinhardtii, phototropin plays a vital role in progression of the sexual life cycle and in the control of the eye spot size and light sensitivity Phototropin is also involved in blue-light mediated changes in the synthesis of chlorophylls, carotenoids, chlorophyll binding proteins. We compared the transcriptome of phototropin knock out (PHOT KO) mutant and wild-type parent to analyze differences in gene expression in high light grown cultures (500 μmol photons m−2 s−1). Our results indicate the up-regulation of genes involved in photosynthetic electron transport chain, carbon fixation pathway, starch, lipid, and cell cycle control genes. With respect to photosynthetic electron transport genes, genes encoding proteins of the cytochrome b6f and ATP synthase complex were up regulated potentially facilitating proton-coupled electron transfer. In addition genes involved in limiting steps in the Calvin cycle Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO), Sidoheptulose 1,7 bisphosphatase (SBPase), Glyceraldehyde-3-phosphate dehydrogenase (3PGDH) and that mediate cell-cycle control (CDK) were also up regulated along with starch synthase and fatty acid biosynthesis genes involved in starch and lipid synthesis. In addition, transmission electron micrographs show increased accumulation of starch granules in PHOT mutant compared to wild type, which is consistent with the higher expression of starch synthase genes. Collectively, the altered patterns of gene expression in the PHOT mutants were associated with a two-fold increase in growth and biomass accumulation compared to wild type when grown in environmental photobioreactors (Phenometrics) that simulate a pond environment. In conclusion, our studies suggest that phototropin may be a master gene regulator that suppresses rapid cell growth and promotes gametogenesis and sexual recombination in wild type strains. |
| FILED | Monday, December 04, 2017 |
| APPL NO | 15/831178 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/405 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 9/12 (20130101) Original (OR) Class C12N 9/22 (20130101) C12N 9/0051 (20130101) C12N 9/1205 (20130101) C12N 15/01 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/64 (20130101) C12P 19/04 (20130101) C12P 23/00 (20130101) Enzymes C12Y 108/01009 (20130101) C12Y 207/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590459 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); Seung-Wuk Lee (Walnut Creek, California); Woo-Jae Chung (El Cerrito, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Seung-Wuk Lee (Walnut Creek, California); Woo-Jae Chung (El Cerrito, California); Jin-woo Oh (Albany, California) |
| ABSTRACT | The present invention provides, inter alia, a device comprising a colorimetric detection layer configured to undergo a color change upon interaction with a first analyte of interest. The detection layer comprises a first plurality of self-assembled fiber bundles. At least a fraction of the fiber bundles undergo a change from a first conformation to a second conformation upon interaction with the first analyte of interest, thereby undergoing a color change. The invention also provides a method for using the system to detect an analyte of interest. |
| FILED | Monday, December 22, 2014 |
| APPL NO | 15/105547 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2795/14131 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) Original (OR) Class C12Q 1/6825 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 21/81 (20130101) G01N 21/783 (20130101) G01N 33/227 (20130101) G01N 2333/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590477 | Koh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Chung-Yan Koh (Dublin, California); Yooli Kim Light (Pleasanton, California); Matthew Ernest Piccini (Belmont, California); Anup K. Singh (Danville, California) |
| ABSTRACT | Embodiments of the present invention are directed toward devices, systems, and methods for purifying nucleic acids to conduct polymerase chain reaction (PCR) assays. In one example, a method includes generating complexes of silica beads and nucleic acids in a lysis buffer, transporting the complexes through an immiscible fluid to remove interfering compounds from the complexes, further transporting the complexes into a density medium containing components required for PCR where the nucleic acids disassociate from the silica beads, and thermocycling the contents of the density medium to achieve PCR. Signal may be detected from labeling agents in the components required for PCR. |
| FILED | Wednesday, September 27, 2017 |
| APPL NO | 15/717524 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 7/52 (20130101) B01L 2200/0668 (20130101) B01L 2300/087 (20130101) B01L 2300/0803 (20130101) B01L 2300/1827 (20130101) B01L 2400/0409 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590498 | Valdez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Carlos A. Valdez (San Ramon, California); Nicholas A. Be (Oakland, California); Brian Bennion (Tracy, California); Tim Carpenter (Livermore, California); Heather Ann Enright (Livermore, California); Felice Lightstone (Fremont, California); Mike Malfatti (San Ramon, California); Margaret Windy McNerney (Pleasanton, California); Tuan H. Nguyen (Livermore, California) |
| ABSTRACT | Described herein are oxime compounds capable of inactivating a nerve agent, blood brain barrier (BBB)-penetration, and/or reactivation of nerve agent-inhibited acetylcholinesterase (AChE) and related methods, systems and compositions for inactivation of one or more nerve agents, therapeutic and/or prophylactic treatment of an individual, and/or decomposition of nerve agent for decontamination. |
| FILED | Monday, May 15, 2017 |
| APPL NO | 15/595400 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/15 (20130101) A61K 31/221 (20130101) A61K 31/4192 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 251/58 (20130101) Heterocyclic Compounds C07D 213/20 (20130101) C07D 241/04 (20130101) Enzymes C12Y 301/01007 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590776 | Dutta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Sandip Dutta (Greenville, South Carolina); James Zhang (Greenville, South Carolina); Gary Michael Itzel (Simpsonville, South Carolina); John McConnell Delvaux (Fountain Inn, South Carolina); Matthew Troy Hafner (Honea Path, South Carolina) |
| ABSTRACT | A turbine component includes a root and an airfoil extending from the root to a tip opposite the root. The airfoil forms a leading edge and a trailing edge portion extending to a trailing edge. A plurality of axial cooling channels in the trailing edge portion of the airfoil are arranged to permit axial flow of a cooling fluid from an interior of the turbine component at the trailing edge portion to an exterior of the turbine component at the trailing edge portion. A method of making a turbine component includes forming an airfoil having a trailing edge portion with axial cooling channels. The axial cooling channels are arranged to permit axial flow of a cooling fluid from an interior to an exterior of the turbine component at the trailing edge portion. A method of cooling a turbine component is also disclosed. |
| FILED | Monday, June 06, 2016 |
| APPL NO | 15/174332 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) F01D 5/186 (20130101) Original (OR) Class F01D 5/187 (20130101) F01D 5/282 (20130101) F01D 9/041 (20130101) F01D 25/005 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/22 (20130101) F05D 2230/31 (20130101) F05D 2230/237 (20130101) F05D 2240/122 (20130101) F05D 2240/304 (20130101) F05D 2250/183 (20130101) F05D 2250/184 (20130101) F05D 2250/185 (20130101) F05D 2260/202 (20130101) F05D 2260/204 (20130101) F05D 2300/175 (20130101) F05D 2300/6033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590843 | Maxwell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Ryan M. Maxwell (Lexington, South Carolina); David R. Dixon (Warrenville, South Carolina); David W. Hawver (Aiken, South Carolina); Tommy D. Gleaton (Springfield, South Carolina) |
| ABSTRACT | A portable generator includes a combustion engine. The portable generator includes an electric generator coupled to the combustion engine. The portable generator can include a load bank. When the electric generator operates at a first voltage and generates less than a threshold amount, the load bank is coupled to the electric generator in a first configuration. When the electric generator operates at a second voltage that is different than the first voltage, the load bank is coupled to the electric generator in a second configuration that is different than the first configuration. |
| FILED | Wednesday, December 13, 2017 |
| APPL NO | 15/840481 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 63/048 (20130101) Original (OR) Class Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 9/107 (20130101) H02P 9/305 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591123 | Dimasi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BrightSpace Technologies, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | BrightSpace Technologies, Inc. (Boulder, Colorado) |
| INVENTOR(S) | Joseph A. Dimasi (Boulder, Colorado) |
| ABSTRACT | A solar light system may include two stages of optical concentration with intermediate removal of infrared radiation between the optical concentration stages. A second stage of optical concentration may prepare multiple concentrating beams of processed solar radiation with visible light with each such concentrating beam directed to a different corresponding light conduit for transmission to an interior space for interior lighting. System modularization may provide flexibility to accommodate a variety of interior lighting applications. |
| FILED | Friday, July 01, 2016 |
| APPL NO | 15/740754 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Non-portable Lighting Devices; Systems Thereof; Vehicle Lighting Devices Specially Adapted for Vehicle Exteriors F21S 11/00 (20130101) F21S 11/005 (20130101) Original (OR) Class F21S 11/007 (20130101) Optical Elements, Systems, or Apparatus G02B 6/0001 (20130101) G02B 6/0008 (20130101) G02B 6/4298 (20130101) G02B 17/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591257 | Barr et al. |
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| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Christian Barr (Kansas City, Missouri); Justin Tannehill (Kansas City, Missouri) |
| ABSTRACT | A multi-layer body armor plate includes a strike plate; a mesh layer positioned over the strike plate, the mesh layer having a number of open cells; and an outer skin layer positioned over the mesh layer so as to encapsulate the open cells of the mesh layer between the strike plate and the outer skin layer. The open cells of the mesh layer may entrap air or may be filled with expandable, buoyant foam. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/208676 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/12 (20130101) B32B 15/16 (20130101) B32B 15/046 (20130101) B32B 2260/025 (20130101) B32B 2264/04 (20130101) B32B 2307/558 (20130101) B32B 2571/02 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/08 (20130101) F41H 5/0457 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591519 | Qiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Wei Qiao (Lincoln, Nebraska); Xiang Gong (Lincoln, Nebraska) |
| ABSTRACT | A wind turbine generator fault detection method is described. The method includes acquiring current data from a wind turbine generator during operation, determining frequency demodulated signals and amplitude demodulated signals by frequency demodulating and amplitude demodulating the current data, resampling the frequency and amplitude demodulated signals corresponding to the current data, monitoring a frequency spectra of the resampled frequency and amplitude demodulated signals corresponding to the current data to identify one or more excitations in the frequency spectra. In response to identifying one or more excitations in the frequency spectra at one or more of the variable fault characteristic frequencies, the method includes generating and transmitting an alert that indicates that a wind turbine generator fault is detected. |
| FILED | Wednesday, May 29, 2013 |
| APPL NO | 13/904469 |
| ART UNIT | 2865 — Printing/Measuring and Testing |
| CURRENT CPC | Wind Motors F03D 7/0296 (20130101) F03D 17/00 (20160501) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2270/334 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 19/2509 (20130101) Original (OR) Class G01R 31/343 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591582 | Musgrove et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); James C. West (Stillwater, Oklahoma) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); James C. West (Stillwater, Oklahoma) |
| INVENTOR(S) | Cameron Musgrove (Albuquerque, New Mexico); Robert Riley (Albuquerque, New Mexico); James C. West (Stillwater, Oklahoma) |
| ABSTRACT | Various technologies for mitigating distortion in coherent image products generated from SAR data are described herein. Synthetic aperture radar (SAR) datasets generated based upon SAR returns from first and second passes of a SAR platform over a scene are received. The SAR datasets can be co-notched at matching sample indices to improve coherence of SAR images generated from the datasets. Windowed SAR data is generated by applying independent windows to subsets of each of the datasets to reduce sidelobe levels of their image impulse responses. Coherent image products are generated based upon the windowed SAR data, wherein an image quality of the coherent image products is improved as compared to coherent image products generated based upon the SAR datasets. |
| FILED | Thursday, November 17, 2016 |
| APPL NO | 15/354033 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/023 (20130101) Original (OR) Class G01S 13/9023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592207 | Sadowski et al. |
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| FUNDED BY |
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| APPLICANT(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| ASSIGNEE(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| INVENTOR(S) | Greg Sadowski (Boxborough, Massachusetts); Wayne Burleson (Boxborough, Massachusetts) |
| ABSTRACT | A conversion unit converts operands from a conventional number system that represents each binary number in the operands as one bit to redundant number system (RNS) operands that represent each binary number as a plurality of bits. An arithmetic logic unit performs an arithmetic operation on the RNS operands in a direction from a most significant bit (MSB) to a least significant bit (LSB). The arithmetic logic unit stops performing the arithmetic operation prior to performing the arithmetic operation on a target binary number indicated by a dynamic precision associated with the RNS operands. In some cases, a power supply provides power to bit slices in the arithmetic logic unit and a clock signal generator provides clock signals to the bit slices. Gate logic is configured to gate the power or the clock signals provided to a subset of the bit slices. |
| FILED | Monday, April 08, 2019 |
| APPL NO | 16/378055 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/729 (20130101) G06F 7/4824 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592424 | Beard et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arm Limited (Cambridge, United Kingdom) |
| ASSIGNEE(S) | Arm Limited (Cambridge, United Kingdom) |
| INVENTOR(S) | Jonathan Curtis Beard (Austin, Texas); Stephan Diestelhorst (Cambridge, United Kingdom) |
| ABSTRACT | A mechanism is provided for efficient coherence state modification of cached data stored in a range of addresses in a coherent data processing system in which data coherency is maintained across multiple caches. A tag search structure is maintained that identifies address tags and coherence states of cached data indexed by address tags. In response to a request from a device internal to or external from the coherence network, the tag search structure is searched to identify address tags of cached data for which the coherence state is to be modified and requests are issued in the data processing system to modify a coherence state of cached lines with the identified address tags. The request from the external device may specify a range of addresses for which a coherence state change is sought. The tag search structure may be implemented as search tree, for example. |
| FILED | Tuesday, November 21, 2017 |
| APPL NO | 15/819378 |
| ART UNIT | 2135 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/082 (20130101) G06F 12/084 (20130101) G06F 12/109 (20130101) G06F 12/1009 (20130101) Original (OR) Class G06F 12/1063 (20130101) G06F 2212/283 (20130101) G06F 2212/621 (20130101) G06F 2212/651 (20130101) G06F 2212/652 (20130101) G06F 2212/656 (20130101) G06F 2212/657 (20130101) G06F 2212/682 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592774 | Bremer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Peer-Timo Bremer (Livermore, California); Hyojin Kim (Livermore, California); Jayaraman J. Thiagarajan (Livermore, California) |
| ABSTRACT | A system for identifying in an image an object that is commonly found in a collection of images and for identifying a portion of an image that represents an object based on a consensus analysis of segmentations of the image. The system collects images of containers that contain objects for generating a collection of common objects within the containers. To process the images, the system generates a segmentation of each image. The image analysis system may also generate multiple segmentations for each image by introducing variations in the selection of voxels to be merged into a segment. The system then generates clusters of the segments based on similarity among the segments. Each cluster represents a common object found in the containers. Once the clustering is complete, the system may be used to identify common objects in images of new containers based on similarity between segments of images and the clusters. |
| FILED | Friday, August 11, 2017 |
| APPL NO | 15/675496 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6215 (20130101) G06K 9/6218 (20130101) Original (OR) Class G06K 9/6256 (20130101) Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 2207/30112 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592817 | Hamann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Hendrik F. Hamann (Yorktown Heights, New York); Youngdeok Hwang (White Plains, New York); Levente Klein (Tuckahoe, New York); Jonathan Lenchner (North Salem, New York); Siyuan Lu (Yorktown Heights, New York); Fernando J. Marianno (New York, New York); Gerald J. Tesauro (Croton-on-Hudson, New York); Theodore G. van Kessel (Millbrook, New York) |
| ABSTRACT | A parameter-based multi-model blending method and system are described. The method includes selecting a parameter of interest among parameters estimated by each of a set of individual models, running the set of individual models with a range of inputs to obtain a range of estimates of the parameters from each of the set of individual models, and identifying, for each of the set of individual models, critical parameters among the parameters estimated, the critical parameters exhibiting a specified correlation with an error in estimation of the parameter of interest. For each subspace of combinations of the critical parameters, obtaining a parameter-based blended model is based on blending the set of individual models in accordance with the subspace of the critical parameters, the subspace defining a sub-range for each of the critical parameters. |
| FILED | Monday, July 13, 2015 |
| APPL NO | 14/797777 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 16/285 (20190101) G06F 17/10 (20130101) G06F 17/5009 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592818 | Hamann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Hendrik F. Hamann (Yorktown Heights, New York); Youngdeok Hwang (White Plains, New York); Levente Klein (Tuckahoe, New York); Jonathan Lenchner (North Salem, New York); Siyuan Lu (Yorktown Heights, New York); Fernando J. Marianno (New York, New York); Gerald J. Tesauro (Croton-on-Hudson, New York); Theodore G. van Kessel (Millbrook, New York) |
| ABSTRACT | A parameter-based multi-model blending method and system are described. The method includes selecting a parameter of interest among parameters estimated by each of a set of individual models, running the set of individual models with a range of inputs to obtain a range of estimates of the parameters from each of the set of individual models, and identifying, for each of the set of individual models, critical parameters among the parameters estimated, the critical parameters exhibiting a specified correlation with an error in estimation of the parameter of interest. For each subspace of combinations of the critical parameters, obtaining a parameter-based blended model is based on blending the set of individual models in accordance with the subspace of the critical parameters, the subspace defining a sub-range for each of the critical parameters. |
| FILED | Tuesday, July 14, 2015 |
| APPL NO | 14/798824 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 16/285 (20190101) G06F 17/10 (20130101) G06F 17/5009 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592834 | Wayne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SUNPOWER CORPORATION (San Jose, California) |
| ASSIGNEE(S) | SUNPOWER CORPORATION (San Jose, California) |
| INVENTOR(S) | Gary Wayne (Berkeley, California); Alexander Frumkin (San Rafael, California); Michael Zaydman (San Rafael, California); Scott Lehman (Martinez, California); Jules Brenner (Novato, California) |
| ABSTRACT | Embodiments may include systems and methods to create and edit a representation of a worksite, to create various data objects, to classify such objects as various types of pre-defined “features” with attendant properties and layout constraints. As part of or in addition to classification, an embodiment may include systems and methods to create, associate, and edit intrinsic and extrinsic properties to these objects. A design engine may apply of design rules to the features described above to generate one or more solar collectors installation design alternatives, including generation of on-screen and/or paper representations of the physical layout or arrangement of the one or more design alternatives. Some embodiments may provide viewing, creating, and manipulating of multiple versions of a solar collector layout design for a particular installation worksite. The use of versions may allow analysis of alternative layouts, alternative feature classifications, and cost and performance data corresponding to alternative design choices. Version summary information providing a representative comparison between versions across a number of dimensions may be provided. |
| FILED | Thursday, March 02, 2017 |
| APPL NO | 15/448107 |
| ART UNIT | 3629 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 2201/00 (20180501) Electric Digital Data Processing G06F 16/219 (20190101) G06F 17/5004 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/067 (20130101) G06Q 10/06313 (20130101) Original (OR) Class G06Q 50/165 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 10/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593434 | Lahoda |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WESTINGHOUSE ELECTRIC COMPANY LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | Edward J. Lahoda (Edgewood, Pennsylvania) |
| ABSTRACT | The invention relates to compositions and methods for coating a zirconium alloy (e.g., ceramic-containing) cladding tube for use with fuel rods in a nuclear water reactor. The coating includes an intermediate oxidation resistant layer and a SiC containing layer at least partially deposited on the intermediate oxidation resistant layer. The SiC containing layer can include a plurality of fibers. The SiC containing layer may also be on the outer surface of end plugs. The invention provides improved capability for the zirconium alloy cladding to withstand normal and accident conditions in the nuclear water reactor. |
| FILED | Wednesday, March 12, 2014 |
| APPL NO | 14/205967 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 3/07 (20130101) Original (OR) Class G21C 3/10 (20130101) G21C 3/20 (20130101) G21C 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593610 | Formicone |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Integra Technologies, Inc. (El Segundo, California) |
| ASSIGNEE(S) | Integra Technologies, Inc. (El Segundo, California) |
| INVENTOR(S) | Gabriele Formicone (Chandler, Arizona) |
| ABSTRACT | A semiconductor power device including a base plate; an input lead; an output lead; a field effect transistor (FET) power die disposed over the base plate, wherein the FET power die includes a set of source fingers, a set of drain fingers, and a set of gate fingers disposed directly over an active region, wherein the gate fingers are configured to receive an input signal from the input lead, and wherein the FET power die is configured to process the input signal to generate an output signal at the drain fingers for routing to the output lead; and electrical conductors (wirebonds or ribbons) bonded to the source and/or drain directly over the active region of the FET power die. The electrical conductors produce additional thermal paths between the active region and the base plate for thermal management of the FET power die. |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/027074 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/34 (20130101) Original (OR) Class H01L 23/481 (20130101) H01L 23/492 (20130101) H01L 23/528 (20130101) H01L 23/535 (20130101) H01L 23/642 (20130101) H01L 23/49562 (20130101) H01L 23/49894 (20130101) H01L 24/48 (20130101) H01L 29/73 (20130101) H01L 29/778 (20130101) H01L 29/1608 (20130101) H01L 29/2003 (20130101) H01L 2224/48157 (20130101) H01L 2224/48177 (20130101) H01L 2224/48195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593755 | Kagan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Korea Institute of Geoscience and Mineral Resources (Daejeon, South Korea) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Korea Institute of Geoscience and Mineral Resources (Daejeon, South Korea) |
| INVENTOR(S) | Cherie R. Kagan (Bala Cynwyd, Pennsylvania); Ji-Hyuk Choi (Daejeon, South Korea); Han Wang (Philadelphia, Pennsylvania); Soong Ju Oh (Seoul, South Korea) |
| ABSTRACT | Colloidal nanocrystal electronic devices including multiple types of nanocrystal device elements including nanocrystal metallic electrodes, nanocrystal insulators, and nanocrystal insulators. Colloidal nanocrystal electronic devices may be produced by forming multiple nanocrystal electronic device elements on a substrate. |
| FILED | Thursday, April 06, 2017 |
| APPL NO | 16/091119 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/08 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02554 (20130101) H01L 21/02573 (20130101) H01L 21/02601 (20130101) H01L 21/02628 (20130101) H01L 29/43 (20130101) H01L 29/0665 (20130101) Original (OR) Class H01L 29/7869 (20130101) H01L 29/78681 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593879 | Schrade et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Constantin Schrade (Cambridge, Massachusetts); Liang Fu (Winchester, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Constantin Schrade (Cambridge, Massachusetts); Liang Fu (Winchester, Massachusetts) |
| ABSTRACT | In a weak link of two s-wave superconductors (SCs) coupled via a time-reversal-invariant (TRI) topological superconducting (TSC) island, a Josephson current can flow due to Cooper pairs tunneling in and out of spatially separated Majorana Kramers pairs (MKPs), which are doublets of Majorana bound states (MBSs). The sign of the resulting Josephson current is fixed by the joint parity of the four Majorana bound states that make up the MKPs on the TSC island. This parity-controlled Josephson effect can be used as a read-out mechanism for the joint parity in Majorana-based quantum computing. For a TSC island with four terminals, the SC leads can address a Majorana superconducting qubit (MSQ) formed by the charge ground states of the TSC island's terminals. Cooper pair splitting enables single-qubit operations, qubit read-out, as well as two-qubit entangling gates. Hence, TSC islands between SC leads may provide an alternative approach to superconducting quantum computation. |
| FILED | Thursday, January 10, 2019 |
| APPL NO | 16/244176 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 49/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593938 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Yingchao Yu (Ithaca, New York); Weidong Zhou (Ithaca, New York); Hao Chen (Ithaca, New York); Hector D. Abruna (Ithaca, New York) |
| ABSTRACT | A nanoparticle and a method for fabricating the nanoparticle utilize a decomposable material yoke located within permeable organic polymer material shell and separated from the permeable organic polymer material shell by a void space. When the decomposable material yoke comprises a sulfur material and the permeable organic polymer material shell comprises a material permeable to both a sulfur material vapor and a lithium ion within a battery electrolyte the nanoparticle may be used within an electrode for a Li/S battery absent the negative effects of battery electrode materials expansion. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 15/691112 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/134 (20130101) H01M 4/136 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/0404 (20130101) H01M 4/602 (20130101) H01M 4/1395 (20130101) H01M 4/1397 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593941 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Apple Inc. (Cupertino, California) |
| ASSIGNEE(S) | Apple Inc. (Cupertino, California) |
| INVENTOR(S) | Hongli Dai (Los Altos, California); Huiming Wu (San Jose, California); Dapeng Wang (Sunnyvale, California) |
| ABSTRACT | Mixed-metal oxides and lithiated mixed-metal oxides are disclosed that involve compounds according to, respectively, NixMnyCozMeαOβ and Li1+γNixMnyCozMeαOβ. In these compounds, Me is selected from B, Na, Mg, Al, Si, K, Ca, Sc, Ti, V, Cr, Fe, Cu, Zn, Ga, Ge, Zr, Nb, Mo, Ru, Ag, In, and combinations thereof; 0≤x≤1; 0≤y≤1; 0≤z<1; x+y+z>0; 0≤α≤0.5; and x+y+α>0. For the mixed-metal oxides, 1≤β≤5. For the lithiated mixed-metal oxides, −0.1≤γ≤1.0 and 1.9≤β≤3. The mixed-metal oxides and the lithiated mixed-metal oxides include particles having an average density greater than or equal to 90% of an ideal crystalline density. |
| FILED | Tuesday, August 07, 2018 |
| APPL NO | 16/057388 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 15/02 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 45/006 (20130101) C01G 51/00 (20130101) C01G 51/04 (20130101) C01G 51/006 (20130101) C01G 51/50 (20130101) C01G 51/66 (20130101) C01G 53/006 (20130101) C01G 53/50 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/76 (20130101) C01P 2002/77 (20130101) C01P 2004/03 (20130101) C01P 2004/51 (20130101) C01P 2004/61 (20130101) C01P 2006/10 (20130101) C01P 2006/11 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20075 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1016 (20130101) H01M 4/131 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) Original (OR) Class H01M 4/525 (20130101) H01M 4/1391 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593996 | Vaughey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | John T. Vaughey (Elmhurst, Illinois); Niya Sa (Darien, Illinois); Hao Wang (Lemont, Illinois); Baris Key (Lemont, Illinois) |
| ABSTRACT | An electrochemical cell includes a high voltage cathode configured to operate at 1.5 volts or greater, an anode including Mg0, and an electrolyte including an at least one organic solvent, at least one magnesium salt, and at least one additive agent including a Lewis base, wherein the electrolyte is halogen-free. |
| FILED | Thursday, August 24, 2017 |
| APPL NO | 15/685234 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 5/00 (20130101) Acyclic or Carbocyclic Compounds C07C 211/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/054 (20130101) H01M 10/0567 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 2300/0025 (20130101) H01M 2300/0028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594106 | Link et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Emily F. Link (Livermore, California); David A. Alessi (Livermore, California); Leon C. Haefner (Oakland, California); Jerald A. Britten (Clayton, California) |
| ABSTRACT | Grating pair architectures used for short pulse stretching, compression and pulse shaping are enabled for use at arbitrary use angles without inducing spatial frequency chirp. These symmetric out-of-plane diffractive grating arrangements are capable of adding or removing spatial, temporal and angular chirp at any incidence angle. |
| FILED | Wednesday, September 05, 2018 |
| APPL NO | 16/122769 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/005 (20130101) H01S 3/0057 (20130101) Original (OR) Class H01S 3/2325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594172 | Tangudu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Jagadeesh Tangudu (South Windsor, Connecticut); Beata I. Wawrzyniak (South Windsor, Connecticut); John A. Sharon (West Hartford, Connecticut); James T. Beals (West Hartford, Connecticut); Tahany Ibrahim El-Wardany (Bloomfield, Connecticut); Wayde R. Schmidt (Pomfret Center, Connecticut) |
| ABSTRACT | An electrical device includes an electromagnetic component configured to generate a magnetic flux. The electromagnetic component includes a soft magnetically-conductive material configured to pass magnetic flux therethrough along a flux path. The soft magnetically-conductive material includes at least one grain oriented portion having metal grains that are oriented parallel with respect to the magnetic flux. |
| FILED | Friday, November 11, 2016 |
| APPL NO | 15/349643 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 8/12 (20130101) C21D 9/0068 (20130101) Alloys C22C 38/02 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/25 (20130101) H01F 41/0213 (20130101) Dynamo-electric Machines H02K 1/02 (20130101) Original (OR) Class H02K 1/16 (20130101) H02K 1/2766 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594227 | Blasko |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Vladimir Blasko (Avon, Connecticut) |
| ABSTRACT | A matrix converter system having a current control mode operation is provided. The system includes a matrix converter having a switching matrix. The matrix converter is coupled at its low-voltage side to a generator and at its output load side to a load. A controller having a pulse width modulation (PWM) control circuit is configured to control the matrix converter via its switching matrix to increase energy within the internal inductances of the generator when the switching matrix causes a short circuit. A feed forward calculator is configured to calculate a feed forward output phase angle. The feed forward output phase angle is an estimation of an angle between an output current vector and an output voltage vector that represent feedback signals of current and voltage output by the matrix converter. The angular position of the voltage output vector is adjusted as a function of the feed forward output phase angle to align angular position or phase angle of the voltage output vector that represents the voltage output with a selected angular position or phase angle. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 16/362533 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 5/271 (20130101) H02M 5/297 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594492 | Edwards et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Nathan J. Edwards (Colorado Springs, Colorado); Jason Hamlet (Albuquerque, New Mexico); Mitchell Tyler Martin (Albuquerque, New Mexico) |
| ABSTRACT | A computing module is described herein, wherein the computing module is configured to perform acts including generating a digital signature for a printed circuit board (PCB), wherein the digital signature is based upon a sensor signal generated by a sensor that is electrically coupled to at least one of a trace of the PCB or an electrical component of the PCB. The acts further include determining that the PCB is authentic and is free of tampering based upon the digital signature. The acts additionally include outputting an indication that the PCB is authentic and is free of tampering responsive to determining that the PCB is authentic and is free of tampering. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/624907 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3247 (20130101) Original (OR) Class H04L 9/3278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10595447 | Campbell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Levi A. Campbell (Poughkeepsie, New York); Richard C. Chu (Poughkeepsie, New York); Milnes P. David (Poughkeepsie, New York); Michael J. Ellsworth, Jr. (Lagrangeville, New York); Madhusudan K. Iyengar (Foster City, California); Roger R. Schmidt (Poughkeepsie, New York); Robert E. Simons (Poughkeepsie, New York) |
| ABSTRACT | Energy efficient control of cooling system cooling of an electronic system is provided based, in part, on weighted cooling effectiveness of the components. The control includes automatically determining speed control settings for multiple adjustable cooling components of the cooling system. The automatically determining is based, at least in part, on weighted cooling effectiveness of the components of the cooling system, and the determining operates to limit power consumption of at least the cooling system, while ensuring that a target temperature associated with at least one of the cooling system or the electronic system is within a desired range by provisioning, based on the weighted cooling effectiveness, a desired target temperature change among the multiple adjustable cooling components of the cooling system. The provisioning includes provisioning applied power to the multiple adjustable cooling components via, at least in part, the determined control settings. |
| FILED | Tuesday, June 12, 2018 |
| APPL NO | 16/005823 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 23/1932 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/2079 (20130101) H05K 7/20836 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10588734 | MacEwan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Matthew R. MacEwan (St. Louis, Missouri); Jingwei Xie (St. Louis, Missouri); Zack Ray (St. Louis, Missouri); Younan Xia (St. Louis, Missouri) |
| ABSTRACT | A three-dimensional electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a flexible deposited fiber network of varying density including a first and second set of set of electrospun fibers. The second set of electrospun fibers is coupled to the first. A first portion of the flexible deposited fiber network includes a higher density of fibers than a second portion of the flexible deposited fiber network, and the tensile strength of first portion is higher than that of the second portion. The scaffold is sufficiently flexible to facilitate application of scaffold to uneven surfaces of the tissue substrate, and enables movement of the scaffold by the tissue substrate. The first and second set of fibers are configured to degrade within three months after application, and each fiber of the deposited fiber network has a diameter of 1-1000 nanometers. |
| FILED | Wednesday, August 14, 2019 |
| APPL NO | 16/540335 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/02 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/22 (20130101) A61L 15/42 (20130101) A61L 27/14 (20130101) A61L 27/50 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/05 (20190201) B29C 48/142 (20190201) Apparatus for Enzymology or Microbiology; C12M 25/14 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0076 (20130101) D01D 5/0092 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/728 (20130101) D04H 3/016 (20130101) D04H 3/073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588860 | Turos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Edward Turos (Wesley Chapel, Florida); Raphael Labruere (Creteil, France); Ryan Scott Cormier (Lutz, Florida); Renaud Sicard (Coral Gables, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Edward Turos (Wesley Chapel, Florida); Raphael Labruere (Creteil, France); Ryan Scott Cormier (Lutz, Florida); Renaud Sicard (Coral Gables, Florida) |
| ABSTRACT | The present invention comprises poly(vinyl benzoate) nanoparticle suspensions as molecular carriers. These nanoparticles can be formed by nanoprecipitation of poly(vinyl benzoate) in water using Pluronic F68 as surfactant, to create spherical nanostructures measuring about 200-250 nm in diameter which are stable in phosphate buffer and blood serum, and only slowly degrade in the presence of esterases. Kinetics experiments in phosphate buffer indicate that 78% of the coumarin-6 was encapsulated within the polymer matrix of the nanoparticle, and the residual 22% of coumarin-6 was surface-bound and quickly released. The nanoparticles are non-toxic in vitro towards human epithelial cells (IC50>1000 μg/mL) and primary bovine primary aortic endothelial cells (IC50>500 μg/mL), and exert non-observable bactericidal activity against a selection of representative test microbes (MIC>250 μg/mL). Poly(vinyl benzoate) nanoparticles are suitable carriers for molecular delivery of lipophilic small molecules such as drugs pharmaceutical and imaging agents. |
| FILED | Thursday, August 04, 2016 |
| APPL NO | 15/228686 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/10 (20130101) A61K 9/0019 (20130101) A61K 9/146 (20130101) Original (OR) Class A61K 9/5138 (20130101) A61K 47/10 (20130101) A61K 47/6933 (20170801) A61K 49/0039 (20130101) A61K 49/0043 (20130101) A61K 49/0093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588997 | Pokorski |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Jonathan Pokorski (Cleveland, Ohio) |
| ABSTRACT | A polymer nanofiber scaffold includes a plurality of melt extruded nanofibers that are chemically modified to append surface functionality to the nanofibers. |
| FILED | Tuesday, April 24, 2018 |
| APPL NO | 15/961712 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/02 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/26 (20130101) Original (OR) Class A61L 15/26 (20130101) A61L 15/26 (20130101) A61L 15/44 (20130101) A61L 15/425 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/56 (20130101) A61L 27/60 (20130101) A61L 2400/12 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 67/04 (20130101) C08L 71/02 (20130101) C08L 71/02 (20130101) C08L 71/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589087 | Tyler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wicab, Inc. (Middleton, Wisconsin) |
| ASSIGNEE(S) | WICAB, INC. (Middleton, Wisconsin) |
| INVENTOR(S) | Mitchell Eugene Tyler (Madison, Wisconsin); Yuri Petrovich Danilov (Middleton, Wisconsin); Paul Bach-y-Rita (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to systems and methods for management of brain and body functions and sensory perception. For example, the present invention provides systems and methods of sensory substitution and sensory enhancement (augmentation) as well as motor control enhancement. The present invention also provides systems and methods of treating diseases and conditions, as well as providing enhanced physical and mental health and performance through sensory substitution, sensory enhancement, and related effects. |
| FILED | Tuesday, April 21, 2015 |
| APPL NO | 14/692419 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/112 (20130101) A61B 5/486 (20130101) A61B 5/0492 (20130101) A61B 5/682 (20130101) A61B 5/686 (20130101) A61B 5/726 (20130101) A61B 5/1116 (20130101) A61B 5/1123 (20130101) A61B 5/1124 (20130101) A61B 5/4005 (20130101) A61B 5/4023 (20130101) A61B 5/4047 (20130101) A61B 5/4528 (20130101) A61B 5/6803 (20130101) A61B 5/7225 (20130101) A61B 5/7455 (20130101) A61B 5/7475 (20130101) A61B 5/14553 (20130101) A61B 2562/046 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0548 (20130101) Original (OR) Class A61N 1/36025 (20130101) A61N 1/36082 (20130101) A61N 1/36103 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/012 (20130101) G06F 3/015 (20130101) G06F 3/016 (20130101) G06F 3/038 (20130101) G06F 3/0383 (20130101) G06F 3/03547 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589252 | Locke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida) |
| INVENTOR(S) | Bruce R. Locke (Tallahassee, Florida); Robert Wandell (Tallahassee, Florida) |
| ABSTRACT | A reactor system that includes a single reactor or a plurality of parallel reactors. A method that includes injecting a mixture including liquid water and a gas, into at least one electrically-conductive inlet capillary tube of a continuously-flowing plasma reactor to generate a flowing liquid film region on one or more internal walls of the continuously-flowing plasma reactor with a gas stream flowing through the flowing liquid film region; propagating a plasma discharge along the flowing liquid film region from at least one electrically-conductive inlet capillary to an electrically-conductive outlet capillary tube at an opposing end of the continuously-flowing plasma reactor; dissociating the liquid water in the plasma discharge to form a plurality of dissociation products; producing hydrogen peroxide and nitrogen oxides from the plurality of dissociation products. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/205941 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) Original (OR) Class B01J 2219/0805 (20130101) B01J 2219/0845 (20130101) B01J 2219/0869 (20130101) B01J 2219/0884 (20130101) B01J 2219/0894 (20130101) Acyclic or Carbocyclic Compounds C07C 29/48 (20130101) C07C 29/48 (20130101) C07C 31/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589829 | Tan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Xiaobo Tan (East Lansing, Michigan); Feitian Zhang (Greenbelt, Maryland); Jianxun Wang (Plainsboro, New Jersey); John Thon (Mason, Michigan) |
| ABSTRACT | A robotic submersible includes a housing having a body and a tail. In another aspect, a pump and a pump tank adjust the buoyancy of a submersible housing. In a further aspect, a first linear actuator controls the pump and/or a buoyancy, and/or a second linear actuator controls a position of a battery and/or adjusts a center of gravity. Another aspect includes a pump and at least one linear actuator that control gliding movements of the housing. In still a further aspect, a motor couples a tail with a body, such that the motor controls the movements of the tail to create a swimming movement. Moreover, an additional aspect provides a controller selectively operating the pump, first actuator, second actuator, and motor to control when swimming and gliding movements occur. |
| FILED | Thursday, July 20, 2017 |
| APPL NO | 15/655072 |
| ART UNIT | 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) Original (OR) Class B63G 2008/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590057 | Groves et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | John T. Groves (Princeton, New Jersey); Xinyi Chen (Princeton, New Jersey) |
| ABSTRACT | Methods of C—H bond fluorination using non-heme manganese catalyst are described herein. For example, a method comprises providing a reaction mixture including a non-heme manganese catalyst, a substrate comprising an sp3 C—H bond and a fluorinating agent and converting the sp3 C—H bond to a C—F bond in the presence of the non-heme manganese catalyst or a derivative thereof. |
| FILED | Wednesday, December 14, 2016 |
| APPL NO | 16/060665 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/22 (20130101) B01J 31/32 (20130101) B01J 31/1815 (20130101) B01J 31/2256 (20130101) B01J 2231/40 (20130101) B01J 2531/72 (20130101) B01J 2531/0238 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 39/00 (20130101) C07B 59/00 (20130101) C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 17/14 (20130101) C07C 17/14 (20130101) C07C 17/14 (20130101) C07C 22/08 (20130101) C07C 25/13 (20130101) C07C 45/63 (20130101) Original (OR) Class C07C 45/63 (20130101) C07C 45/63 (20130101) C07C 45/63 (20130101) C07C 49/697 (20130101) C07C 49/755 (20130101) C07C 49/813 (20130101) C07C 67/287 (20130101) C07C 67/287 (20130101) C07C 67/287 (20130101) C07C 67/307 (20130101) C07C 67/307 (20130101) C07C 69/63 (20130101) C07C 69/65 (20130101) C07C 69/78 (20130101) C07C 231/12 (20130101) C07C 231/12 (20130101) C07C 231/12 (20130101) C07C 233/14 (20130101) C07C 233/18 (20130101) C07C 253/30 (20130101) C07C 253/30 (20130101) C07C 255/35 (20130101) C07C 269/06 (20130101) C07C 269/06 (20130101) C07C 271/16 (20130101) C07C 2601/18 (20170501) C07C 2602/08 (20170501) C07C 2602/10 (20170501) C07C 2603/32 (20170501) Heterocyclic Compounds C07D 209/48 (20130101) C07D 209/50 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 13/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590176 | Snow et al. |
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| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Christopher D. Snow (Fort Collins, Colorado); Thaddaus R. Huber (Fort Collins, Colorado) |
| ABSTRACT | The present disclosure provides compositions and methods for preparing engineered porous protein crystals comprising at least one guest molecule. |
| FILED | Tuesday, June 20, 2017 |
| APPL NO | 15/627788 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 14/195 (20130101) C07K 14/205 (20130101) Original (OR) Class C07K 14/235 (20130101) C07K 14/435 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/12 (20130101) C12N 2795/10222 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/58 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/207 (20130101) G01N 2223/612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590181 | Boyden et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Edward S. Boyden (Cambridge, Massachusetts); Yongku Peter Cho (Vernon, Connecticut); Nathan C. Klapoetke (Ashburn, Virginia); Amy S. Chuong (Ashburn, Virginia); Fei Chen (Cambridge, Massachusetts) |
| ABSTRACT | The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of mutant light-activated ion channels and variants thereof. |
| FILED | Saturday, April 18, 2015 |
| APPL NO | 14/653040 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/405 (20130101) C07K 14/705 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/5076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590294 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Yu Teng Liang (Chicago, Illinois); Ethan B. Secor (Evanston, Illinois); Pradyumna L. Prabhumirashi (Chicago, Illinois); Kanan P. Puntambekar (Chicago, Illinois); Michael L. Geier (Chicago, Illinois); Bok Y. Ahn (Cambridge, Massachusetts); Jennifer A. Lewis (Cambridge, Massachusetts) |
| ABSTRACT | A rapid, scalable methodology for graphene dispersion and concentration with a polymer-organic solvent medium, as can be utilized without centrifugation, to enhance graphene concentration. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 15/905358 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/01 (20130101) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 5/0023 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/19 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/32 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/14 (20130101) C09D 11/36 (20130101) C09D 11/38 (20130101) Original (OR) Class C09D 11/52 (20130101) C09D 11/322 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0005 (20130101) H01L 51/0045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590414 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHEASTERN UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | NORTHEASTERN UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Ke Zhang (Boston, Massachusetts); Xueguang Lu (Boston, Massachusetts) |
| ABSTRACT | The disclosed subject matter relates to brush polymer-oligonucleotide conjugates comprising oligonucleotides covalently attached to the backbone of a non-cationic, sterically congested brush polymer and the use of such polymer-oligonucleotide conjugates in antisense gene regulation and as diagnostic agents. |
| FILED | Thursday, August 04, 2016 |
| APPL NO | 15/750360 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0054 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 2261/18 (20130101) C08G 2261/78 (20130101) C08G 2261/228 (20130101) C08G 2261/1432 (20130101) C08G 2261/3324 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/1135 (20130101) C12N 2310/11 (20130101) C12N 2310/51 (20130101) C12N 2310/351 (20130101) C12N 2310/3515 (20130101) C12N 2320/11 (20130101) C12N 2320/32 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590426 | Ducat et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Daniel Christopher Ducat (Lansing, Michigan); Katherine Osteryoung (Williamston, Michigan); Joshua Scott MacCready (Lansing, Michigan) |
| ABSTRACT | Described herein are mutant cyanobacterial cell populations that have a smaller mean cell length than wild type cyanobacterial cell populations of the same species. |
| FILED | Tuesday, August 22, 2017 |
| APPL NO | 15/683411 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590459 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); Seung-Wuk Lee (Walnut Creek, California); Woo-Jae Chung (El Cerrito, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Seung-Wuk Lee (Walnut Creek, California); Woo-Jae Chung (El Cerrito, California); Jin-woo Oh (Albany, California) |
| ABSTRACT | The present invention provides, inter alia, a device comprising a colorimetric detection layer configured to undergo a color change upon interaction with a first analyte of interest. The detection layer comprises a first plurality of self-assembled fiber bundles. At least a fraction of the fiber bundles undergo a change from a first conformation to a second conformation upon interaction with the first analyte of interest, thereby undergoing a color change. The invention also provides a method for using the system to detect an analyte of interest. |
| FILED | Monday, December 22, 2014 |
| APPL NO | 15/105547 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2795/14131 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) Original (OR) Class C12Q 1/6825 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 21/81 (20130101) G01N 21/783 (20130101) G01N 33/227 (20130101) G01N 2333/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591017 | Walsh |
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| FUNDED BY |
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| APPLICANT(S) | Ohio University (Athens, Ohio) |
| ASSIGNEE(S) | Ohio University (Athens, Ohio) |
| INVENTOR(S) | Kenneth K. Walsh (Athens, Ohio) |
| ABSTRACT | A resetting semi-passive stiffness damper (RSPSD) triggering assembly and a RSPSD and method of use for damping movement of an object. Exemplary embodiments of a RSPSD triggering assembly include, for example, a rotatable disc and a spring-loaded lever arranged between the disc and a slotted channel. A sensor is provided and communicates with a bypass valve on the cylinder. A change in the direction of movement of the disc causes reciprocation of the lever in the channel, which causes the sensor to send open and close signals to the bypass valve. In some embodiments, a single disc may be replaced with two interacting discs. A RSPSD equipped with such a triggering assembly is usable to damp movement of an object of interest. |
| FILED | Monday, March 20, 2017 |
| APPL NO | 15/463636 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/98 (20130101) E04B 1/985 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 9/02 (20130101) E04H 2009/026 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 9/512 (20130101) F16F 9/3214 (20130101) F16F 9/3292 (20130101) F16F 9/5126 (20130101) Original (OR) Class F16F 15/02 (20130101) F16F 2228/001 (20130101) F16F 2228/10 (20130101) F16F 2228/066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591275 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Hui Wang (Cleveland, Ohio); Andrew Rollins (Highland Heights, Ohio); Xiaoyong Fu (Shaker Heights, Ohio) |
| ABSTRACT | This disclosure relates to an OCT apparatus configured to generate to electromagnetic (e.g., optical) signals having two different polarization states. Two or more silicon optical amplifiers (SOAs) can be configured to maintain a respective polarization state in an optical input signal provided from a light source (e.g., a broadband light source). The different polarization states can be combined by an optical combiner (e.g., a polarization maintaining fiber coupler) and provided to drive a reference arm and a sample arm implemented in an OCT system. |
| FILED | Thursday, February 01, 2018 |
| APPL NO | 15/886739 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/0084 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02011 (20130101) Original (OR) Class G01B 9/02091 (20130101) G01B 2290/60 (20130101) G01B 2290/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591392 | Torres et al. |
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| FUNDED BY |
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| APPLICANT(S) | APPLIKATE TECHNOLOGIES LLC (Weston, Connecticut) |
| ASSIGNEE(S) | APPLIKATE TECHNOLOGIES LLC (Washington, District of Columbia) |
| INVENTOR(S) | Richard Torres (East Haven, Connecticut); Michael Levene (New Haven, Connecticut) |
| ABSTRACT | A biopsy-sized tissue sample is stained for quick imaging. A significant amount of permeation enhancer is included in a mixed solution of permeant enhancer, fixative or dehydrant, and one or two fluorescent dyes to simultaneously dehydrate and dye the tissue sample. The permeation enhancer, e.g., 10% to 50% in the mixed solution, achieves an image of dyed tissue in the contacted tissue sample at a depth of at least 200 um within no more than 1.5 hours. One of the fluorescent dyes is a fluorescent nuclear dye such as DAPI, SYTOX green, acridine orange, propidium iodide, or a Hoechst dye. The other fluorescent dye is a fluorescent protein dye such as eosin or rhodamine B. The tissue sample is cleared with a clearing agent having a refractive index of at least 1.4[R2], e.g., using BABB. The mixed solution may further include Chloroform or other morphology preservative. |
| FILED | Thursday, July 03, 2014 |
| APPL NO | 14/324019 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) Original (OR) Class G01N 33/4833 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591403 | Roy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Krishnendu Roy (Atlanta, Georgia); Kirsten Parratt (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present disclosure can comprise a method for multiplexed analysis. The method can comprise acquiring interrogation data associated with a microstructure in a population and analyzing the microstructure based on the interrogation data. In some embodiments, the microstructure can have a different shape than at least another microstructure in the population and comprise a plurality of cells. Additionally, the acquiring the interrogation data can comprise acquiring interrogation data of microstructures in a population at a structure concentration of at least 100 microstructures/μL. Therefore, in some embodiments, acquiring the interrogation data can comprises flowing the population through a flow cytometer. |
| FILED | Thursday, March 16, 2017 |
| APPL NO | 16/085077 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0652 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/147 (20130101) Original (OR) Class G01N 15/1434 (20130101) G01N 15/1475 (20130101) G01N 15/1484 (20130101) G01N 21/6486 (20130101) G01N 33/50 (20130101) G01N 33/569 (20130101) G01N 2015/149 (20130101) G01N 2015/1006 (20130101) G01N 2015/1445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591435 | Conte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Sean Conte (Gaithersburg, Maryland); Gabriel G. Rodriguez-Calero (Willseyville, New York); Cen Tan (Fremont, California); Kenneth Hernandez-Burgos (Ithaca, New York); Hector D. Abruna (Ithaca, New York); Nicole Ritzert (Renfrew, Pennsylvania); Daniel C. Ralph (Ithaca, New York); Wan Li (Kensington, California) |
| ABSTRACT | Electropolymerized polymer or copolymer films on a conducting substrate (e.g., graphene) and methods of making such films. The films may be part of multilayer structures. The films can be formed by anodic or cathodic electropolymerization of monomers. The films and structures (e.g., multilayer structures) can be used in devices such as, for example, electrochromic devices, electrical-energy storage devices, photo-voltaic devices, field-effect transistor devices, electrical devices, electronic devices, energy-generation devices, and microfluidic devices. |
| FILED | Friday, April 03, 2015 |
| APPL NO | 15/301085 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 2200/12 (20130101) B01L 2300/0645 (20130101) B01L 2300/0887 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 9/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/302 (20130101) Original (OR) Class G01N 27/4146 (20130101) G01N 27/4167 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/155 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/035 (20130101) H01G 9/042 (20130101) H01G 9/145 (20130101) H01G 9/2059 (20130101) H01G 11/36 (20130101) H01G 11/38 (20130101) H01G 11/48 (20130101) H01G 11/58 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/022466 (20130101) H01L 51/0006 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/137 (20130101) H01M 4/0404 (20130101) H01M 4/0466 (20130101) H01M 4/608 (20130101) H01M 4/663 (20130101) H01M 4/1399 (20130101) H01M 6/02 (20130101) H01M 10/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/542 (20130101) Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591474 | Katchman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Benjamin Katchman (Tempe, Arizona); Karen Anderson (Scottsdale, Arizona); Joseph Smith (Tempe, Arizona); Jennifer Blain Christen (Chandler, Arizona) |
| ABSTRACT | Systems and methods for low-cost point-of-care immunoassay are provided. The system comprises an emitter, two optical interference filters, a microscope slide, a photodiode detector, a circuit, and a measuring unit. The detector is placed upon the second filter, the slide, the first filter, and then the emitter. The emitter comprises non-organic light emitting diodes (LEDs) or organic light emitting diodes (OLEDs) that emits light of a first color. The slide is spotted with biofluid from a patient. Biomarkers in the biofluid is bound with immobilized fluorophores that emit light of a second color when stimulated by the light of the first color. The first and second filters band-pass the light of the first and second colors, respectively. The detector detects light of the second color. The current outputted from the detector is converted into a relatively-large output voltage by a circuit. A measuring unit measures the ramp time of the output voltage. The ramp time is to be used to determine the concentration of the fluorophores, which in turn is related to the concentration of the biomarkers. |
| FILED | Friday, May 06, 2016 |
| APPL NO | 15/579038 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/58 (20130101) G01N 33/582 (20130101) G01N 33/6857 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 33/54386 (20130101) G01N 2333/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591902 | Jayakumar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Hrishikesh Jayakumar (West Lafayette, Indiana); Arnab Raha (West Lafayette, Indiana); Vijay Raghunathan (West Lafayette, Indiana) |
| ABSTRACT | A microcontroller system which employs an intermediate approach in hybrid FRAM-SRAM that involves memory mapping of program sections to retain the reliability benefits provided by FRAM while performing almost as efficiently as an SRAM-based system. They system utilizes an energy-aware memory mapping method which maps different program sections to the hybrid FRAM-SRAM MCU such that energy consumption is minimized without sacrificing reliability. The method comprises a memory initialization map, which performs a one-time characterization to find the optimal memory map for the functions that constitute a program. The method further comprises an energy alignment, a hardware/software method that aligns the system's powered-on time intervals to function execution boundaries, which results in further improvements in energy efficiency and performance. |
| FILED | Tuesday, January 03, 2017 |
| APPL NO | 15/397721 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 21/02 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 22/06 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/404 (20130101) G05B 19/418 (20130101) Original (OR) Class G05B 19/4142 (20130101) G05B 23/0297 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10591983 | Ho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Chen-Han Ho (Madison, Wisconsin); Karthikeyan Sankaralingam (Madison, Wisconsin); Sung Kim (Madison, Wisconsin) |
| ABSTRACT | A specialized memory access processor is placed between a main processor and accelerator hardware to handle memory access for the accelerator hardware. The architecture of the memory access processor is designed to allow lower energy memory accesses than can be obtained by the main processor in providing data to the hardware accelerator while providing the hardware accelerator with a sufficiently high bandwidth memory channel. In some embodiments, the main processor may enter a sleep state during accelerator calculations to substantially lower energy consumption. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/212676 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/3293 (20130101) Original (OR) Class G06F 9/3881 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592466 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nam Sung Kim (Champaign, Illinois); Zhenhong Liu (Champaign, Illinois) |
| ABSTRACT | A GPU architecture employs a crossbar switch to preferentially store operand vectors in a compressed form allowing reduction in the number of memory circuits that must be activated during an operand fetch and to allow existing execution units to be used for scalar execution. Scalar execution can be performed during branch divergence. |
| FILED | Thursday, May 12, 2016 |
| APPL NO | 15/152810 |
| ART UNIT | 2125 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 1/3203 (20130101) G06F 1/3243 (20130101) G06F 1/3275 (20130101) G06F 1/3287 (20130101) G06F 9/3836 (20130101) G06F 9/3887 (20130101) G06F 9/30021 (20130101) G06F 9/30058 (20130101) G06F 9/30141 (20130101) G06F 15/7839 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592687 | Kapadia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); United States of America as Represented by The Secretary of The Navy (Arlington, Virginia) |
| INVENTOR(S) | Apu Kapadia (Bloomington, Indiana); Robert E. Templeman (Bloomington, Indiana); David Crandall (Bloomington, Indiana); Mohammed Korayem (Bloomington, Indiana) |
| ABSTRACT | A method and device for classifying collected images. The method and device include instructions to compare a captured image to a known set of images to determine the location depicted therein; and applying a classification upon the image based upon the determined location depicted therein and whether the determined location indicates that the image has the potential to depict privacy sensitive information. |
| FILED | Thursday, October 09, 2014 |
| APPL NO | 15/029559 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/51 (20190101) G06F 16/5838 (20190101) G06F 16/5854 (20190101) G06F 16/5862 (20190101) G06F 16/5866 (20190101) G06F 21/6245 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/78 (20130101) G06K 9/00664 (20130101) G06K 9/00771 (20130101) G06K 9/4671 (20130101) G06K 9/6202 (20130101) G06K 9/6267 (20130101) G06K 9/6297 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592765 | Fathi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pointivo, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Pointivo, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Habib Fathi (Atlanta, Georgia); Miguel M. Serrano (Marietta, Georgia); Bradden John Gross (Atlanta, Georgia); Daniel L. Ciprari (Atlanta, Georgia) |
| ABSTRACT | Examples of various method and systems are provided for information generation from images of a building. In one example, 2D building and/or building element information can be generated from 2D images of the building that are overlapping. 3D building and building element information can be generated from the 2D building and/or building element information. The 2D image information can be combined with 3D information about the building and/or building element to generate projective geometry information. Clustered 3D information can be generated by partitioning and grouping 3D data points. An information set associated with the building and/or at least one building element can then be generated. |
| FILED | Friday, January 19, 2018 |
| APPL NO | 15/875149 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00201 (20130101) G06K 9/00208 (20130101) G06K 9/342 (20130101) Original (OR) Class G06K 9/00664 (20130101) G06K 9/6218 (20130101) G06K 2209/40 (20130101) Image Data Processing or Generation, in General G06T 7/55 (20170101) G06T 17/00 (20130101) G06T 2207/10028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593755 | Kagan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Korea Institute of Geoscience and Mineral Resources (Daejeon, South Korea) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Korea Institute of Geoscience and Mineral Resources (Daejeon, South Korea) |
| INVENTOR(S) | Cherie R. Kagan (Bala Cynwyd, Pennsylvania); Ji-Hyuk Choi (Daejeon, South Korea); Han Wang (Philadelphia, Pennsylvania); Soong Ju Oh (Seoul, South Korea) |
| ABSTRACT | Colloidal nanocrystal electronic devices including multiple types of nanocrystal device elements including nanocrystal metallic electrodes, nanocrystal insulators, and nanocrystal insulators. Colloidal nanocrystal electronic devices may be produced by forming multiple nanocrystal electronic device elements on a substrate. |
| FILED | Thursday, April 06, 2017 |
| APPL NO | 16/091119 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/08 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02554 (20130101) H01L 21/02573 (20130101) H01L 21/02601 (20130101) H01L 21/02628 (20130101) H01L 29/43 (20130101) H01L 29/0665 (20130101) Original (OR) Class H01L 29/7869 (20130101) H01L 29/78681 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593821 | Korgel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Brian A. Korgel (Round Rock, Texas); Taylor B. Harvey (Austin, Texas); Carl Jackson Stolle (Austin, Texas); Vahid Akhavan (Austin, Texas) |
| ABSTRACT | Methods of making a semiconductor layer from nanocrystals are disclosed. A film of nanocrystals capped with a ligand can be deposited onto a substrate; and the nanocrystals can be irradiated with one or more pulses of light. The pulsed light can be used to substantially remove the ligands from the nanocrystals and leave the nanocrystals unsintered or sintered, thereby providing a semiconductor layer. Layered structures comprising these semiconductor layers with an electrode are also disclosed. Devices comprising such layered structures are also disclosed. |
| FILED | Saturday, September 12, 2015 |
| APPL NO | 15/509075 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02422 (20130101) H01L 21/02485 (20130101) H01L 21/02491 (20130101) H01L 21/02502 (20130101) H01L 21/02562 (20130101) H01L 21/02568 (20130101) H01L 21/02601 (20130101) H01L 21/02628 (20130101) H01L 31/028 (20130101) H01L 31/0296 (20130101) H01L 31/0322 (20130101) H01L 31/0326 (20130101) H01L 31/0445 (20141201) Original (OR) Class H01L 31/1864 (20130101) H01L 31/02327 (20130101) H01L 31/022425 (20130101) H01L 31/022466 (20130101) H01L 31/035209 (20130101) H01L 2031/0344 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593856 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | George Mason University (Fairfax, Virginia) |
| ASSIGNEE(S) | GEORGE MASON UNIVERSITY (Fairfax, Virginia) |
| INVENTOR(S) | Qiliang Li (Fairfax, Virginia); Sheng Yu (Fairfax, Virginia); Abbas Arab (Fairfax, Virginia) |
| ABSTRACT | Devices for generating electrical energy along with methods of fabrication and methods of use are disclosed. An example device can comprise one or more layers of a transition metal dichalcogenide material. An example device can comprise a mechano-electric generator. Another example device can comprise a thermoelectric generator. |
| FILED | Thursday, May 26, 2016 |
| APPL NO | 15/574065 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02568 (20130101) H01L 31/035227 (20130101) H01L 35/00 (20130101) H01L 35/02 (20130101) H01L 35/16 (20130101) Original (OR) Class H01L 35/34 (20130101) H01L 41/18 (20130101) H01L 41/113 (20130101) Electric Machines Not Otherwise Provided for H02N 2/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593871 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| INVENTOR(S) | Judy Z. Wu (Lawrence, Kansas); Jamie Wilt (Olathe, Kansas); Ryan Goul (Topeka, Kansas); Jagaran Acharya (Lawrence, Kansas) |
| ABSTRACT | Methods for forming tunnel barrier layers are provided, including a method comprising exposing a surface of a material, the surface free of oxygen, to an initial water pulse for a pulse time and at a pulse temperature, the pulse time and pulse temperature selected to maximize hydroxylation of the surface; and exposing the hydroxylated surface to alternating, separated pulses of precursors under conditions to induce reactions between the hydroxylated surface and the precursors to form a tunnel barrier layer on the surface of the material via atomic layer deposition (ALD), the tunnel barrier layer having an average thickness of no more than 1 nm and being formed without an intervening interfacial layer between the tunnel barrier layer and the surface of the material. |
| FILED | Tuesday, May 22, 2018 |
| APPL NO | 15/985979 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/223 (20130101) H01L 39/2493 (20130101) H01L 43/08 (20130101) H01L 43/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593901 | Holloway et al. |
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| FUNDED BY |
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| APPLICANT(S) | NANOPHOTONICA, INC. (Lake Mary, Florida) |
| ASSIGNEE(S) | NanoPhotonica, Inc. (Lake Mary, Florida) |
| INVENTOR(S) | Paul H. Holloway (Gainesville, Florida); Jake Hyvonen (Gainesville, Florida); Jesse R. Manders (Gainesville, Florida); Alexandre Titov (Gainesville, Florida); Jean Tokarz (Hawthorne, Florida); Krishna Acharya (Gainesville, Florida) |
| ABSTRACT | A process for improving the external quantum efficiency of a light emitting diode (LED) is provided by exposing one or more components of an LED, a partially assembled LED, or a completely assembled LED to an amount of hydrogen or hydrogen gas, or to an atmosphere containing higher quantities of hydrogen or hydrogen gas for a period of exposure time. Kits and processes for constructing a light emitting diode having an improved external quantum efficiency is further provided, which includes exposing one or more components of an LED, a partially assembled LED, or a completely assembled LED to an amount of hydrogen or hydrogen gas, or to an atmosphere containing higher quantities of hydrogen or hydrogen gas for a period of exposure time. |
| FILED | Friday, May 20, 2016 |
| APPL NO | 15/575700 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 7/22 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) H01L 33/14 (20130101) H01L 33/36 (20130101) H01L 33/60 (20130101) H01L 33/504 (20130101) H01L 33/505 (20130101) H01L 51/502 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10593938 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Yingchao Yu (Ithaca, New York); Weidong Zhou (Ithaca, New York); Hao Chen (Ithaca, New York); Hector D. Abruna (Ithaca, New York) |
| ABSTRACT | A nanoparticle and a method for fabricating the nanoparticle utilize a decomposable material yoke located within permeable organic polymer material shell and separated from the permeable organic polymer material shell by a void space. When the decomposable material yoke comprises a sulfur material and the permeable organic polymer material shell comprises a material permeable to both a sulfur material vapor and a lithium ion within a battery electrolyte the nanoparticle may be used within an electrode for a Li/S battery absent the negative effects of battery electrode materials expansion. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 15/691112 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/134 (20130101) H01M 4/136 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/0404 (20130101) H01M 4/602 (20130101) H01M 4/1395 (20130101) H01M 4/1397 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594261 | Dutta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Moumita Dutta (San Antonio, Texas); Ruyan Guo (San Antonio, Texas); Amar Bhalla (San Antonio, Texas); Soutik Betal (San Antonio, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas Systems (Austin, Texas) |
| INVENTOR(S) | Moumita Dutta (San Antonio, Texas); Ruyan Guo (San Antonio, Texas); Amar Bhalla (San Antonio, Texas); Soutik Betal (San Antonio, Texas) |
| ABSTRACT | Disclosed are various embodiments of a terahertz wave modulator. The wave modulator can include one or more layers of piezoelectric/ferroelectric single crystal or polycrystalline material. The crystalline material can be configured to resonate when a low-energy external excitation is applied. An incident terahertz waveform can be dynamically controlled when the incident terahertz waveform interacts with the at least one layer of piezoelectric crystalline material while the at least one layer of piezoelectric crystalline material is resonating. The dynamic control of the incident terahertz waveform can be with respect to at least one of a phase shift and an amplitude modulation of the waveform. |
| FILED | Tuesday, July 18, 2017 |
| APPL NO | 15/652656 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/083 (20130101) Modulation H03C 1/02 (20130101) H03C 1/46 (20130101) H03C 3/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594319 | Friedman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanson, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Joseph S. Friedman (Rochester, New York); Michael L. Geier (Chicago, Illinois); Mark C. Hersam (Wilmette, Illinois); Alan V. Sahakian (Northbrook, Illinois) |
| ABSTRACT | A logic gate and a cascaded logic family is described that uses the unique ambipolar behavior, e.g., of carbon nanotubes. A complementary VT-drop ambipolar carbon nanotube logic can provide a decrease in device count compared to previous ambipolar carbon nanotube field effect transistor logic structures, enabling power and/or speed improvements. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/591833 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 7/501 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0048 (20130101) H01L 51/0554 (20130101) Pulse Technique H03K 19/082 (20130101) Original (OR) Class H03K 19/212 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594409 | Primerano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Richard Anthony Primerano (Philadelphia, Pennsylvania); Moshe Kam (Philadelphia, Pennsylvania); Kapil R. Dandekar (Philadelphia, Pennsylvania); Cole Gindhart (Philadelphia, Pennsylvania) |
| ABSTRACT | Ultrasonic through metal communication systems are an effective solution for transmitting data across a metal barrier when the structural integrity of the barrier cannot be compromised by physically penetrating it. Substantial improvements in through metal communication systems have been made in recent years, enabling high speed communications of up to 15 Mbps, as well as power transmission up to 30 W across flat walls. A system is described that allows for ultrasonic through metal communication across the wall of a steel tube. Primary challenges of 1) transducer contact, 2) curvature effect on echoes, and 3) alignment are analyzed and addressed through the use of radial mode piezoelectric transducers, transducer “horns”, and Electromagnetic Acoustic Transducers (EMATs). The resulting system shows no significant loss due to changes in alignment, allows for the use of either piezoelectric transducers or EMATs externally, and achieves max data rates of approximately 600 kbps without echo equalization. |
| FILED | Friday, December 02, 2016 |
| APPL NO | 15/368015 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Transmission H04B 11/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594705 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shouhuai Xu (Helotes, Texas); Moustafa Elsayed Saleh (San Antonio, Texas); Edward Paul Ratazzi (Rome, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shouhuai Xu (Helotes, Texas); Moustafa Elsayed Saleh (San Antonio, Texas); Edward Paul Ratazzi (Rome, New York) |
| ABSTRACT | Disclosed herein are new methods and systems for detecting obfuscated programs. We build a recursive traversal disassembler that extracts the control flow graph of binary files. This allows us to detect the presence of interleaving instructions, which is typically an indication of the opaque predicate anti-disassembly trick. Our detection system uses some novel features based on referenced instructions and the extracted control flow graph that clearly distinguishes between obfuscated and normal files. When these are combined with a few features based on file structure, we achieve a very high detection rate of obfuscated files. |
| FILED | Thursday, October 06, 2016 |
| APPL NO | 15/287705 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) Original (OR) Class H04L 63/1425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10588321 | Morra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Idaho (Moscow, Idaho) |
| ASSIGNEE(S) | University of Idaho (Moscow, Idaho) |
| INVENTOR(S) | Matthew J. Morra (Moscow, Idaho); Inna E. Popova (Moscow, Idaho); Jeremiah Dubie (Medford, Oregon) |
| ABSTRACT | Disclosed are embodiments of a method of using mustard meal or mustard meal extract. Certain embodiments concern controlling vegetable sprouting, such as potato sprouting. Vegetables, such as potatoes, may be exposed to products resulting from mustard meal, or an extract thereof, contacting water. Other embodiments concern a process for controlling plant pests, such as insects, nematodes, fungi, weeds, and combinations thereof, with specific embodiments being particularly useful for weed suppression. Certain embodiments comprise extracting glucosinolates from plant material, or processed plant material, selected from the family Brassicaceae, particularly from the genera Brassica and Sinapis. Extracted glucosinolates can be hydrolyzed to form active compounds, or alternatively, they can be hydrolyzed in situ, by simultaneously or sequentially applying myrosinase. The extract can be applied to plants, to the soil adjacent to the plant. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/863680 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/02 (20130101) A01N 25/02 (20130101) A01N 25/04 (20130101) A01N 65/00 (20130101) Original (OR) Class A01N 65/08 (20130101) A01N 65/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588336 | Jun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Hawaii (Honolulu, Hawaii) |
| ASSIGNEE(S) | University of Hawaii (Honolulu, Hawaii) |
| INVENTOR(S) | Soojin Jun (Honolulu, Hawaii); Jin Hong Mok (Honolulu, Hawaii); Sung Hee Park (Honolulu, Hawaii) |
| ABSTRACT | Perishable products, such as food products, can be preserved by cooling to temperatures below their freezing point without ice crystallization. In some embodiments, the perishable product is cooled to temperatures below the freezing point of water while a pulsed electric field and oscillating magnetic field are applied to the product. Apparatus for supercooling perishable products are also provided and include a pulsed electric field generator and an oscillating magnetic field generator. |
| FILED | Thursday, October 18, 2018 |
| APPL NO | 16/164628 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0252 (20130101) A01N 1/0284 (20130101) A01N 1/0294 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 3/26 (20130101) A23L 3/32 (20130101) A23L 3/36 (20130101) Original (OR) Class Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10588941 | Xiong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Na Xiong (State College, Pennsylvania); Mingcan Xia (Brookline, Massachusetts) |
| ABSTRACT | The invention provides compositions and methods for targeting CCR10 and/or the CCR10/ligand axis to modulate the immune response in a subject. |
| FILED | Friday, July 20, 2018 |
| APPL NO | 16/040592 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/195 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 14/523 (20130101) C07K 14/7158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590397 | Rayment et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ivan Rayment (Fitchburg, Wisconsin); Karl Wetterhorn (Madison, Wisconsin) |
| ABSTRACT | Compositions and methods for increasing resistance to Fusarium infection in plants are provided herein. Polynucleotides, polypeptides, and expression constructs for expressing mutant UDP-glycosyltransferase proteins, plants comprising the polynucleotides, polypeptides or expression constructs, and methods of producing transgenic plants are also provided. |
| FILED | Friday, March 02, 2018 |
| APPL NO | 15/910717 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1051 (20130101) Original (OR) Class C12N 15/8282 (20130101) Enzymes C12Y 204/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590431 | Borrell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The State of Queensland acting through the Department of Agriculture, Fisheries and Forestry (Brisbane, Australia); The Texas A and M University System (College Station, Texas); Grains Research and Development Corporation (Barton, Australia) |
| ASSIGNEE(S) | The State of Queensland (Brisbane, Australia); The Texas A and M University System (College Station, Texas); Grains Research and Development Corporation (Barton, Australia) |
| INVENTOR(S) | Andrew Kenneth Borrell (Warwick, Australia); David Robert Jordan (Warwick, Australia); John Mullet (College Station, Texas); Patricia Klein (College Station, Texas) |
| ABSTRACT | The present disclosure teaches the generation of drought tolerant plants. The present disclosure enables manipulation of a phenotypic characteristic referred to as “stay-green” to facilitate drought adaptation in plants by recombinant, mutagenic and/or breeding and selection methods. Plant management practice systems to increase crop yield and harvest efficiency in water-limited environments are also taught herein. |
| FILED | Friday, November 16, 2012 |
| APPL NO | 14/358725 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/02 (20130101) A01H 5/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/01 (20130101) C12N 15/8273 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10590000 | Hurwitz |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Frances Hurwitz (Shaker Heights, Ohio) |
| ABSTRACT | Aerogels, aerogel composites and methods of making the same are discussed. One example method can include the act of creating a boehmite colloid and adding a hydrolyzed silicon precursor to form a sol. A reinforcement can be infused with the sol and dried to form an aerogel composite. Such a method can also include the acts of performing one or more solvent exchanges and subjecting the gel composite to supercritical drying. Additionally, such a method can include the act of heat treating the aerogel composite. The aerogel composite can be used in high temperature, flexible seals capable of withstanding temperatures, pressures, and compression levels associated with aerodynamic heating generated during flight and in aerospace applications. |
| FILED | Monday, August 11, 2014 |
| APPL NO | 14/456043 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/245 (20130101) B32B 2250/02 (20130101) B32B 2266/04 (20130101) B32B 2305/08 (20130101) B32B 2311/24 (20130101) B32B 2571/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/1585 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/0004 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590044 | Raj |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Sai V. Raj (Strongsville, Ohio) |
| ABSTRACT | An engineered matrix is provided to blunt and self-heal matrix cracks to reduce oxygen ingress into a fiber reinforced composite. |
| FILED | Friday, January 20, 2017 |
| APPL NO | 15/411375 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/565 (20130101) C04B 41/009 (20130101) C04B 41/52 (20130101) Original (OR) Class C04B 41/85 (20130101) C04B 41/4515 (20130101) C04B 41/4523 (20130101) C04B 41/5071 (20130101) C04B 2235/616 (20130101) C04B 2235/3826 (20130101) C04B 2235/3891 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10590517 | Manuel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Michele Viola Manuel (Gainesville, Florida); Derek Hsen Dai Hsu (Portland, Oregon) |
| ABSTRACT | Disclosed herein is a shape memory alloy comprising 48 to 50 atomic percent nickel, 15 to 30 atomic percent hafnium, 1 to 5 atomic percent aluminum; with the remainder being titanium. Disclosed herein too is a method of manufacturing a shape memory alloy comprising mixing together to form an alloy nickel, hafnium, aluminum and titanium in amounts of 48 to 50 atomic percent nickel, 15 to 30 atomic percent hafnium, 1 to 5 atomic percent aluminum; with the remainder being titanium; solution treating the alloy at a temperature of 700 to 1300° C. for 50 to 200 hours; and aging the alloy at a temperature of 400 to 800° C. for a time period of 50 to 200 hours to form a shape memory alloy. |
| FILED | Monday, December 04, 2017 |
| APPL NO | 15/830610 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 1/00 (20130101) C22C 27/00 (20130101) C22C 30/00 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/006 (20130101) C22F 1/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10592622 | Csank et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of Americas as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey T. Csank (Parma, Ohio); Sanjay Garg (Westlake, Ohio) |
| ABSTRACT | A system and method of analyzing an engine model is disclosed. The system and method include performing a Dynamic Systems Analysis on the engine model that includes modifying a transient allowance of the engine model to determine an optimal balance between performance and operability and assessing the conservatism level of the engine model. |
| FILED | Monday, October 02, 2017 |
| APPL NO | 15/722152 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Non-positive-displacement Pumps F04D 27/001 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10588795 | Hansen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government as Represented by the Department of Veteran Affairs (Washington, District of Columbia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Andrew H. Hansen (Minneapolis, Minnesota); Gary D. Goldish (Minneapolis, Minnesota) |
| ABSTRACT | A manual wheelchair including a collapsible frame having a first lateral member that is connected to first and second braces at their respective first ends. A drive wheel axel extends along a first axis of rotation and engages a drive wheel, the first brace, and a portion of a transmission. A push rim axel extends along a second axis of rotation and engages a push rim wheel, the second brace, and a portion of the transmission, which transmits rotation of the push rim to rotation of the drive wheel. The collapsible frame additionally includes a second lateral member that is connected to the first and second braces as their respective second ends. The first and second braces are configured to release the second lateral member to collapse the manual wheelchair. |
| FILED | Monday, September 19, 2016 |
| APPL NO | 15/269868 |
| ART UNIT | 3611 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/023 (20130101) Original (OR) Class A61G 5/024 (20130101) A61G 5/026 (20130101) A61G 5/027 (20130101) Technical Subjects Covered by Former US Classification Y10T 74/20834 (20150115) Y10T 74/20864 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10589118 | Schneider |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BRAINSWAY LTD. (Jerusalem, Israel); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | BRAINSWAY LTD. (Jerusalem, Israel); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | M. Bret Schneider (Portola Valley, California) |
| ABSTRACT | Methods of stimulating a target deep brain region using multiple Transcranial Magnetic Stimulation (TMS) electromagnets positioned over a predetermined cortical regions each having a first-order connection to a target deep brain region and applying TMS so that the applied TMS induces spatial summation and thereby modulation of the target deep brain region. |
| FILED | Thursday, January 18, 2018 |
| APPL NO | 15/874784 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2/02 (20130101) Original (OR) Class A61N 2/006 (20130101) A61N 2/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10593901 | Holloway et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NANOPHOTONICA, INC. (Lake Mary, Florida) |
| ASSIGNEE(S) | NanoPhotonica, Inc. (Lake Mary, Florida) |
| INVENTOR(S) | Paul H. Holloway (Gainesville, Florida); Jake Hyvonen (Gainesville, Florida); Jesse R. Manders (Gainesville, Florida); Alexandre Titov (Gainesville, Florida); Jean Tokarz (Hawthorne, Florida); Krishna Acharya (Gainesville, Florida) |
| ABSTRACT | A process for improving the external quantum efficiency of a light emitting diode (LED) is provided by exposing one or more components of an LED, a partially assembled LED, or a completely assembled LED to an amount of hydrogen or hydrogen gas, or to an atmosphere containing higher quantities of hydrogen or hydrogen gas for a period of exposure time. Kits and processes for constructing a light emitting diode having an improved external quantum efficiency is further provided, which includes exposing one or more components of an LED, a partially assembled LED, or a completely assembled LED to an amount of hydrogen or hydrogen gas, or to an atmosphere containing higher quantities of hydrogen or hydrogen gas for a period of exposure time. |
| FILED | Friday, May 20, 2016 |
| APPL NO | 15/575700 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 7/22 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) H01L 33/14 (20130101) H01L 33/36 (20130101) H01L 33/60 (20130101) H01L 33/504 (20130101) H01L 33/505 (20130101) H01L 51/502 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10594299 | Veeder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Senseeker Engineering Inc. (Goleta, California) |
| ASSIGNEE(S) | SENSEEKER ENGINEERING, INC. (Santa Barbara, California) |
| INVENTOR(S) | Kenton Veeder (Santa Barbara, California); Aaron Bluestone (Goleta, California); Christoph von Jutrzenka Trzebiatowski (Goleta, California); Nishant Dhawan (Santa Barbara, California) |
| ABSTRACT | The present disclosure provides an analog counter circuit for use in a minimal-sized circuitry. The analog counter circuit of the present disclosure can provide much higher resolution versus power consumption and layout area as compared to conventional digital counters. The analog counter circuit of the present disclosure can also provide much better bias supply management, step accuracy, multi-element step uniformity and lower supply spiking as compared to conventional analog counter architectures. The compact size of the disclosed counter circuit allows better integration of arrayed elements, such as, an array of image sensing pixels or an array of artificial neurons. |
| FILED | Thursday, April 12, 2018 |
| APPL NO | 15/951196 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 11/265 (20130101) Original (OR) Class Pulse Technique H03K 25/00 (20130101) Pictorial Communication, e.g Television H04N 5/378 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10591617 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Yuntao Wu (Knoxville, Tennessee); Mariya Zhuravleva (Knoxville, Tennessee); Luis Stand (Knoxville, Tennessee); Charles L. Melcher (Oak Ridge, Tennessee) |
| ABSTRACT | Metal halide optical materials (e.g., scintillator materials or persistent phosphors) are described. More particularly, the optical materials include codoped perovskite-type halides, wherein the codoping ion is present at a molar ratio of 5000 parts per million (ppm) or less with respect to all cations. For example, the optical material can be a codoped trihalide having the formula ABX3 where A is one or more alkali metal, B is one or more alkali earth metal, and X is one or more halide that is doped with up to about 10 atomic percent of a dopant ion and codoped with up to about 5000 ppm of one or more isovalent or aliovalent codopant ion, such as a tetravalent ion (e.g., Zr4+), a trivalent ion (e.g., Sc3+, Y3+, Gd3+, or La3+ ion) or a divalent ion (e.g., Mg2+). The codoped material can have modified afterglow compared to a noncodoped material. |
| FILED | Thursday, May 03, 2018 |
| APPL NO | 15/970581 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/0012 (20130101) C01F 17/0031 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 25/006 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) C01P 2002/52 (20130101) C01P 2002/84 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Measurement of Nuclear or X-radiation G01T 1/201 (20130101) G01T 1/208 (20130101) G01T 1/2018 (20130101) G01T 1/2023 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 10589225 | Olson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Midwest Energy Emissions Corp. (Corsicana, Texas) |
| ASSIGNEE(S) | Midwest Energy Emissions Corp. (Lewis Center, Ohio) |
| INVENTOR(S) | Edwin S. Olson (Grand Forks, North Dakota); Michael J. Holmes (Thompson, North Dakota); John Henry Pavlish (East Grand Forks, Minnesota) |
| ABSTRACT | A promoted activated carbon sorbent is described that is highly effective for the removal of mercury from flue gas streams. The sorbent comprises a new modified carbon form containing reactive forms of halogen and halides. Optional components may be added to increase reactivity and mercury capacity. These may be added directly with the sorbent, or to the flue gas to enhance sorbent performance and/or mercury capture. Mercury removal efficiencies obtained exceed conventional methods. The sorbent can be regenerated and reused. Sorbent treatment and preparation methods are also described. New methods for in-flight preparation, introduction, and control of the active sorbent into the mercury contaminated gas stream are described. |
| FILED | Thursday, May 14, 2015 |
| APPL NO | 14/712558 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/10 (20130101) B01D 53/64 (20130101) Original (OR) Class B01D 2253/102 (20130101) B01D 2257/602 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/02 (20130101) B01J 20/04 (20130101) B01J 20/10 (20130101) B01J 20/12 (20130101) B01J 20/20 (20130101) B01J 20/22 (20130101) B01J 20/027 (20130101) B01J 20/041 (20130101) B01J 20/043 (20130101) B01J 20/106 (20130101) B01J 20/223 (20130101) B01J 20/0262 (20130101) B01J 20/3416 (20130101) B01J 20/28004 (20130101) B01J 20/28016 (20130101) B01J 2220/42 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 95/901 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10588561 | Vale et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fernando Vale (Tampe, Florida); Elliot George Neal (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Fernando Vale (Tampe, Florida); Elliot George Neal (Tampa, Florida) |
| ABSTRACT | System and method for processing, non-concurrently collected, electroencephalogram (EEG) data and resting station functional magnetic resonance imaging (rsfMRI) data, non-invasively, to create a patient-specific three-dimensional (3D) mapping of the patient's functional brain network. The mapping can be used to more precisely identify candidates of resective neurosurgery and to help create a targeted surgical plan for those patients. The methodology automatically maps the patient's unique brain network using non-concurrent EEG and resting state functional MRI (rsfMRI). Generally, the current invention merges non-concurrent EEG data and rsfMRI data to map the patient's epilepsy/seizure network. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/024020 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0476 (20130101) A61B 5/04014 (20130101) A61B 5/4064 (20130101) A61B 5/4094 (20130101) Original (OR) Class A61B 5/7235 (20130101) A61B 5/7285 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) G01R 33/4808 (20130101) G01R 33/5608 (20130101) G01R 33/56341 (20130101) Image Data Processing or Generation, in General G06T 2207/10088 (20130101) G06T 2207/30016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, March 17, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
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THE PANEL
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FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
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FILED
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APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200317.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page